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Search of human proteins with 4507525
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4507525 translocation protein 1 [Homo sapiens]
(399 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4507525 translocation protein 1 [Homo sapiens] 817 0.0
gi|46852388 cell-cycle and apoptosis regulatory protein 1 [Homo ... 59 1e-08
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 55 9e-08
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 54 2e-07
gi|13540523 nucleosomal binding protein 1 [Homo sapiens] 54 3e-07
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f... 52 9e-07
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 52 9e-07
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 52 9e-07
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ... 52 9e-07
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 52 9e-07
gi|11225260 DNA topoisomerase I [Homo sapiens] 52 1e-06
gi|217035093 cyclic nucleotide gated channel alpha 1 isoform 1 [... 51 2e-06
gi|71143141 cyclic nucleotide gated channel alpha 1 isoform 2 [H... 51 2e-06
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 51 2e-06
gi|239750213 PREDICTED: hypothetical protein [Homo sapiens] 50 4e-06
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 50 5e-06
gi|151301171 RNA polymerase II transcription factor TAFII140 [Ho... 49 6e-06
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 49 6e-06
gi|239752449 PREDICTED: hypothetical protein [Homo sapiens] 49 8e-06
gi|19923236 nuclear antigen Sp100 isoform 2 [Homo sapiens] 49 8e-06
gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 fami... 49 1e-05
gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32 fam... 49 1e-05
gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32 fam... 49 1e-05
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 49 1e-05
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 49 1e-05
gi|4504425 high-mobility group box 1 [Homo sapiens] 48 1e-05
gi|221219020 NYD-SP11 protein [Homo sapiens] 47 2e-05
gi|169202818 PREDICTED: similar to hCG1991922 [Homo sapiens] 47 2e-05
gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo ... 47 2e-05
gi|194688135 high-mobility group box 2 [Homo sapiens] 47 3e-05
>gi|4507525 translocation protein 1 [Homo sapiens]
Length = 399
Score = 817 bits (2110), Expect = 0.0
Identities = 399/399 (100%), Positives = 399/399 (100%)
Query: 1 MAERRRHKKRIQEVGEPSKEEKAVAKYLRFNCPTKSTNMMGHRVDYFIASKAVDCLLDSK 60
MAERRRHKKRIQEVGEPSKEEKAVAKYLRFNCPTKSTNMMGHRVDYFIASKAVDCLLDSK
Sbjct: 1 MAERRRHKKRIQEVGEPSKEEKAVAKYLRFNCPTKSTNMMGHRVDYFIASKAVDCLLDSK 60
Query: 61 WAKAKKGEEALFTTRESVVDYCNRLLKKQFFHRALKVMKMKYDKDIKKEKDKGKAESGKE 120
WAKAKKGEEALFTTRESVVDYCNRLLKKQFFHRALKVMKMKYDKDIKKEKDKGKAESGKE
Sbjct: 61 WAKAKKGEEALFTTRESVVDYCNRLLKKQFFHRALKVMKMKYDKDIKKEKDKGKAESGKE 120
Query: 121 EDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGTPKKKETKKKFKLEPHDDQVFLD 180
EDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGTPKKKETKKKFKLEPHDDQVFLD
Sbjct: 121 EDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGTPKKKETKKKFKLEPHDDQVFLD 180
Query: 181 GNEVYVWIYDPVHFKTFVMGLILVIAVIAATLFPLWPAEMRVGVYYLSVGAGCFVASILL 240
GNEVYVWIYDPVHFKTFVMGLILVIAVIAATLFPLWPAEMRVGVYYLSVGAGCFVASILL
Sbjct: 181 GNEVYVWIYDPVHFKTFVMGLILVIAVIAATLFPLWPAEMRVGVYYLSVGAGCFVASILL 240
Query: 241 LAVARCILFLIIWLITGGRHHFWFLPNLTADVGFIDSFRPLYTHEYKGPKADLKKDEKSE 300
LAVARCILFLIIWLITGGRHHFWFLPNLTADVGFIDSFRPLYTHEYKGPKADLKKDEKSE
Sbjct: 241 LAVARCILFLIIWLITGGRHHFWFLPNLTADVGFIDSFRPLYTHEYKGPKADLKKDEKSE 300
Query: 301 TKKQQKSDSEEKSDSEKKEDEEGKVGPGNHGTEGSGGERHSDTDSDRREDDRSQHSSGNG 360
TKKQQKSDSEEKSDSEKKEDEEGKVGPGNHGTEGSGGERHSDTDSDRREDDRSQHSSGNG
Sbjct: 301 TKKQQKSDSEEKSDSEKKEDEEGKVGPGNHGTEGSGGERHSDTDSDRREDDRSQHSSGNG 360
Query: 361 NDFEMITKEELEQQTDGDCEEDEEEENDGETPKSSHEKS 399
NDFEMITKEELEQQTDGDCEEDEEEENDGETPKSSHEKS
Sbjct: 361 NDFEMITKEELEQQTDGDCEEDEEEENDGETPKSSHEKS 399
>gi|46852388 cell-cycle and apoptosis regulatory protein 1 [Homo
sapiens]
Length = 1150
Score = 58.5 bits (140), Expect = 1e-08
Identities = 67/313 (21%), Positives = 125/313 (39%), Gaps = 73/313 (23%)
Query: 86 LKKQFFHRALKVMKMKYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDG 145
LK Q R K +K++ K+ +KE +K + E +++D+KS E K+E+E+K+
Sbjct: 658 LKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDEDDDRKS-------EDDKEEEERKRQE 710
Query: 146 EKEESKKEETPGTPKKKETKKKFKLEPHDDQVFLDGNEVYVWIYDPVHFKTFVMGLILVI 205
E E ++E Y+ +P
Sbjct: 711 EIERQRRERR-----------------------------YILPDEP-------------- 727
Query: 206 AVIAATLFPLWPAEMRVGVYYLSVGAGCFVASILLLAVARCILFLIIWLITGGRHHFWFL 265
A + P W A+ +G F SI+ L+V L+ + + + H F
Sbjct: 728 ---AIIVHPNWAAK-----------SGKFDCSIMSLSV------LLDYRLEDNKEHS-FE 766
Query: 266 PNLTADVGFIDSFRPLYTHEYKGPKADLKKDEKSETKKQQKSDSEEKSDSEKKEDEEGKV 325
+L A++ R YK + +K++K E K+ K D E K E+++DE +
Sbjct: 767 VSLFAELFNEMLQRDFGVRIYKSLLSLPEKEDKKEKDKKSKKD-ERKDKKEERDDETDEP 825
Query: 326 GPGNHGTEGSGGERHSDTDSDRREDDRSQHSSGNGNDFEMITKEELEQQTDGDCEEDEEE 385
P + G ++ D D ++ED R S + E ++E + + E++E++
Sbjct: 826 KPKRRKS-GDDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEEDD 884
Query: 386 ENDGETPKSSHEK 398
++ E K ++
Sbjct: 885 RDEEEMTKRDDKR 897
Score = 43.1 bits (100), Expect = 4e-04
Identities = 45/189 (23%), Positives = 81/189 (42%), Gaps = 35/189 (18%)
Query: 3 ERRRHKKRIQEVGEPS--KEEKAVAKYLRFNCPTKSTNMMGHRVDYFIASKAVDCLLDSK 60
ER+R ++R EP+ AK +F+C S +++ +DY +
Sbjct: 713 ERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVL---LDYRLEDN--------- 760
Query: 61 WAKAKKGEEALFTTRESVVDYCNRLLKKQFFHRALKVMKMKYDKDIKKEKDK-------- 112
K E +LF + N +L++ F R K + +K+ KKEKDK
Sbjct: 761 --KEHSFEVSLFA------ELFNEMLQRDFGVRIYKSLLSLPEKEDKKEKDKKSKKDERK 812
Query: 113 GKAESGKEE-----DKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGTPKKKETKKK 167
K E +E K+ K + KD+K +++ KK+D K++SK ++ ++
Sbjct: 813 DKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDEYDP 872
Query: 168 FKLEPHDDQ 176
+ E +D+
Sbjct: 873 MEAEEAEDE 881
Score = 34.7 bits (78), Expect = 0.16
Identities = 22/80 (27%), Positives = 40/80 (50%), Gaps = 19/80 (23%)
Query: 103 DKDIKKEKDKGKAESGKEEDKK----SKKENIKDEKTKKEKEKKKDGEKEESKKE----- 153
DKD K+++D+ K E +++D K ++++N +DE E E+ +D E + ++E
Sbjct: 835 DKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRD 894
Query: 154 ----------ETPGTPKKKE 163
E P K+KE
Sbjct: 895 DKRDINRYCKERPSKDKEKE 914
Score = 31.6 bits (70), Expect = 1.3
Identities = 26/115 (22%), Positives = 52/115 (45%), Gaps = 13/115 (11%)
Query: 295 KDEKSETKKQQKSDSEEKSDSEKKEDEEGKVGPGNHGTEGSGGERHSDTDSDRREDDRSQ 354
K + E + ++ +++ + D E+K+D E K + T S + + +D R++ S+
Sbjct: 594 KQQLVEKLQGERKEADGEQDEEEKDDGEAK--EISTPTHWSKLDPKTMKVNDLRKELESR 651
Query: 355 HSSGNGNDFEMIT-----------KEELEQQTDGDCEEDEEEENDGETPKSSHEK 398
S G ++I KEE ++ + EEDE+++ E K E+
Sbjct: 652 ALSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDKEEEER 706
Score = 31.6 bits (70), Expect = 1.3
Identities = 64/331 (19%), Positives = 123/331 (37%), Gaps = 90/331 (27%)
Query: 101 KYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKK---EKEKKKDGEKEESKKEETPG 157
K D K D K + K K + TK+ E++K++ E E+S+KEE
Sbjct: 633 KLDPKTMKVNDLRKELESRALSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDED 692
Query: 158 TPKKKETKKKFKLEPHDDQVFLDGNEV-YVWIYDPVHFKTFVMGLILVIAVIAATLFPLW 216
+K E K+ + +++ E Y+ +P A + P W
Sbjct: 693 DDRKSEDDKEEEERKRQEEIERQRRERRYILPDEP-----------------AIIVHPNW 735
Query: 217 PAEMRVGVYYLSVGAGCFVASILLLAVARCILFLIIWLITGGRHHFW--------FLPNL 268
A+ +G F SI+ L+V L+ + + + H + F L
Sbjct: 736 AAK-----------SGKFDCSIMSLSV------LLDYRLEDNKEHSFEVSLFAELFNEML 778
Query: 269 TADVGFIDSFRPLYT--------HEYKGPKADLKKDEKSET------------------- 301
D G + ++ L + + K K D +KD+K E
Sbjct: 779 QRDFG-VRIYKSLLSLPEKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKD 837
Query: 302 KKQQKSD--SEEKSDSEKKEDEEGKVGPGNHGTEGSGGERHSDTDSDRREDDRSQHSSGN 359
KK+ + + E+K + K+D+E + E + + + +++ ED+ +
Sbjct: 838 KKEDRDERKKEDKRKDDSKDDDETE--------EDNNQDEYDPMEAEEAEDEE------D 883
Query: 360 GNDFEMITKEELEQQTDGDCEEDEEEENDGE 390
D E +TK + ++ + C+E ++ + E
Sbjct: 884 DRDEEEMTKRDDKRDINRYCKERPSKDKEKE 914
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 55.5 bits (132), Expect = 9e-08
Identities = 31/84 (36%), Positives = 49/84 (58%), Gaps = 1/84 (1%)
Query: 96 KVMKMKYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEET 155
K K K K+ K+EK++GK E +++ KK ++E ++ K+ K++++ E+ E KKE
Sbjct: 137 KRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERK 196
Query: 156 PGTPKKKETKKKFKLEPH-DDQVF 178
KKKE KK K + D QVF
Sbjct: 197 KERRKKKERKKDRKTDRQTDSQVF 220
Score = 46.6 bits (109), Expect = 4e-05
Identities = 19/69 (27%), Positives = 42/69 (60%)
Query: 99 KMKYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGT 158
K K +K ++ K +G+ E K++++K ++ K + +K K+++K ++E K+E+ G
Sbjct: 96 KRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGK 155
Query: 159 PKKKETKKK 167
++K K+K
Sbjct: 156 RERKRKKRK 164
Score = 46.2 bits (108), Expect = 5e-05
Identities = 26/71 (36%), Positives = 43/71 (60%), Gaps = 3/71 (4%)
Query: 101 KYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGTPK 160
K ++ K++K + K E GKE ++K +KE K K ++EKE++K K+E KK E +
Sbjct: 55 KRERGKKEKKKRKKRERGKERERK-RKEREKQRKERREKERRK--RKKEKKKRERKQRGR 111
Query: 161 KKETKKKFKLE 171
++ KKK + E
Sbjct: 112 RERKKKKERKE 122
Score = 45.4 bits (106), Expect = 9e-05
Identities = 22/69 (31%), Positives = 40/69 (57%)
Query: 99 KMKYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGT 158
+ K ++ +K K + + E +E KK KK+ K E+ K+ + K+K+ EK+ ++ E
Sbjct: 36 RKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERR 95
Query: 159 PKKKETKKK 167
+KKE KK+
Sbjct: 96 KRKKEKKKR 104
Score = 45.4 bits (106), Expect = 9e-05
Identities = 22/83 (26%), Positives = 48/83 (57%)
Query: 87 KKQFFHRALKVMKMKYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGE 146
K++ R K K + ++ KE+++ + E K+ ++ +KE K +K KK++E+K+ G
Sbjct: 52 KERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGR 111
Query: 147 KEESKKEETPGTPKKKETKKKFK 169
+E KK+E ++ + +++ K
Sbjct: 112 RERKKKKERKERERENKQRRERK 134
Score = 43.9 bits (102), Expect = 3e-04
Identities = 29/107 (27%), Positives = 52/107 (48%), Gaps = 2/107 (1%)
Query: 63 KAKKGEEALFTTRESVVDYCNRLLKKQFFHRALKVMKMKYDKDIK--KEKDKGKAESGKE 120
K KK E R+ R +++ R K K K ++ + +E+ K K +E
Sbjct: 65 KRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERE 124
Query: 121 EDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGTPKKKETKKK 167
+ K ++E + ++ KK++ K++ EKE K+E KK+E +KK
Sbjct: 125 RENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKK 171
Score = 42.4 bits (98), Expect = 7e-04
Identities = 22/68 (32%), Positives = 42/68 (61%), Gaps = 3/68 (4%)
Query: 107 KKEKDKGKAESGKEEDKKSKKENIKDEKT---KKEKEKKKDGEKEESKKEETPGTPKKKE 163
+KE++K + E ++E +K KKE K E+ ++E++KKK+ ++ E + ++ +KK
Sbjct: 79 RKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKR 138
Query: 164 TKKKFKLE 171
KKK + E
Sbjct: 139 RKKKRRKE 146
Score = 41.6 bits (96), Expect = 0.001
Identities = 19/73 (26%), Positives = 46/73 (63%), Gaps = 4/73 (5%)
Query: 99 KMKYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGT 158
K K +++ ++++++GK KE+ K+ K+E K+ + K+++ +K+ E+ E ++ +
Sbjct: 45 KRKREREKERKRERGK----KEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKE 100
Query: 159 PKKKETKKKFKLE 171
KK+E K++ + E
Sbjct: 101 KKKRERKQRGRRE 113
Score = 41.6 bits (96), Expect = 0.001
Identities = 21/85 (24%), Positives = 47/85 (55%)
Query: 87 KKQFFHRALKVMKMKYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGE 146
+KQ R K K + +++ + ++ + + + + K+ K+ + E+ K+E+++KK +
Sbjct: 106 RKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKK 165
Query: 147 KEESKKEETPGTPKKKETKKKFKLE 171
+E KK E +KKE ++K + E
Sbjct: 166 EEREKKRERNRKERKKERERKERRE 190
Score = 37.7 bits (86), Expect = 0.018
Identities = 19/66 (28%), Positives = 40/66 (60%), Gaps = 3/66 (4%)
Query: 107 KKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKD---GEKEESKKEETPGTPKKKE 163
++E ++ K +E+ K+ +++ K E+ KKEK+K+K G++ E K++E K++
Sbjct: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90
Query: 164 TKKKFK 169
K++ K
Sbjct: 91 EKERRK 96
Score = 36.2 bits (82), Expect = 0.054
Identities = 14/64 (21%), Positives = 38/64 (59%)
Query: 104 KDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGTPKKKE 163
++ +++K++ + E K E +K +K ++ KK K++++ E+E +KE +++E
Sbjct: 32 RESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERRE 91
Query: 164 TKKK 167
+++
Sbjct: 92 KERR 95
Score = 34.7 bits (78), Expect = 0.16
Identities = 19/69 (27%), Positives = 40/69 (57%), Gaps = 3/69 (4%)
Query: 106 IKKEKDKGKAESGKEEDKKSKKENIKDEKTKKE---KEKKKDGEKEESKKEETPGTPKKK 162
I K + ++E KE ++ K++ ++++ K+E KEKKK ++E K+ E ++K
Sbjct: 25 ISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREK 84
Query: 163 ETKKKFKLE 171
+ K++ + E
Sbjct: 85 QRKERREKE 93
Score = 32.0 bits (71), Expect = 1.0
Identities = 15/60 (25%), Positives = 36/60 (60%), Gaps = 2/60 (3%)
Query: 99 KMKYDKDIKKEKDKG--KAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETP 156
+ K +++ K+E+++ K E ++E ++ KKE K+ + KKE++K + +++ + P
Sbjct: 163 RKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQVFRP 222
Score = 29.6 bits (65), Expect = 5.0
Identities = 19/109 (17%), Positives = 45/109 (41%)
Query: 290 KADLKKDEKSETKKQQKSDSEEKSDSEKKEDEEGKVGPGNHGTEGSGGERHSDTDSDRRE 349
+++ KK+ + K++++ + E K + KKE ++ K E ER R +
Sbjct: 33 ESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREK 92
Query: 350 DDRSQHSSGNGNDFEMITKEELEQQTDGDCEEDEEEENDGETPKSSHEK 398
+ R + + + + E +++ + E E ++ K +K
Sbjct: 93 ERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKK 141
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 54.3 bits (129), Expect = 2e-07
Identities = 33/74 (44%), Positives = 45/74 (60%), Gaps = 6/74 (8%)
Query: 104 KDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESK------KEETPG 157
+D K+EK+K K E K+EDK K+ K +K + +KE KK+ +KEE K K+ETP
Sbjct: 647 EDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPP 706
Query: 158 TPKKKETKKKFKLE 171
KKE KK+ K E
Sbjct: 707 KEVKKEVKKEEKKE 720
Score = 48.5 bits (114), Expect = 1e-05
Identities = 36/90 (40%), Positives = 47/90 (52%), Gaps = 2/90 (2%)
Query: 87 KKQFFHRALKVMKMKYDKD-IKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDG 145
KK+ + K + K DK IKKE+ K E KE K+ KKE K+ K + +KE
Sbjct: 649 KKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKE 708
Query: 146 EKEESKKEETPGTPK-KKETKKKFKLEPHD 174
K+E KKEE K +KE KK+ K P D
Sbjct: 709 VKKEVKKEEKKEVKKEEKEPKKEIKKLPKD 738
Score = 45.1 bits (105), Expect = 1e-04
Identities = 32/90 (35%), Positives = 49/90 (54%), Gaps = 7/90 (7%)
Query: 98 MKMKYDKDIKKEKDKG-----KAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEK--EES 150
+K + K+IKKE+ K K E+ +E KK K+ K E K+EKE KK+ +K +++
Sbjct: 680 VKKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDA 739
Query: 151 KKEETPGTPKKKETKKKFKLEPHDDQVFLD 180
KK TP + KK K K+ ++ V D
Sbjct: 740 KKSSTPLSEAKKPAALKPKVPKKEESVKKD 769
Score = 44.7 bits (104), Expect = 2e-04
Identities = 30/65 (46%), Positives = 34/65 (52%), Gaps = 2/65 (3%)
Query: 108 KEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGTPKKKETKKK 167
KEK K K EDKK +KE K E KKE K +KEE K+E KKE KK+
Sbjct: 634 KEKTVKKETKVKPEDKKEEKEKPKKEVAKKED--KTPIKKEEKPKKEEVKKEVKKEIKKE 691
Query: 168 FKLEP 172
K EP
Sbjct: 692 EKKEP 696
Score = 43.9 bits (102), Expect = 3e-04
Identities = 27/69 (39%), Positives = 37/69 (53%), Gaps = 3/69 (4%)
Query: 103 DKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGTPKKK 162
+K K K E +++ K K E+ K+EK K +KE K +K KKEE PKK+
Sbjct: 622 EKQATDVKPKAAKEKTVKKETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKEE---KPKKE 678
Query: 163 ETKKKFKLE 171
E KK+ K E
Sbjct: 679 EVKKEVKKE 687
Score = 34.7 bits (78), Expect = 0.16
Identities = 26/118 (22%), Positives = 56/118 (47%), Gaps = 3/118 (2%)
Query: 60 KWAKAKKGEEALFTTRESVVDYCNRLLKKQFFHRALKVMKMKYDKDIKKEKDKGKAESGK 119
K K K+ ++ + + + ++ ++K+ +V K+ + + K + K K K
Sbjct: 531 KQTKLKQRADSRESLKPAAKPLPSKSVRKESKEETPEVTKVNHVEKPPKVESKEKVMVKK 590
Query: 120 EEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEET---PGTPKKKETKKKFKLEPHD 174
++ K++ + EK KE+ + E ++K+ T P K+K KK+ K++P D
Sbjct: 591 DKPIKTETKPSVTEKEVPSKEEPSPVKAEVAEKQATDVKPKAAKEKTVKKETKVKPED 648
Score = 34.7 bits (78), Expect = 0.16
Identities = 28/79 (35%), Positives = 43/79 (54%), Gaps = 4/79 (5%)
Query: 96 KVMKMKYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKE-KKKDGEKEESKKEE 154
K +K + K++KKE+ + K E K+ K +KK + + KK K K +KEES K++
Sbjct: 711 KEVKKEEKKEVKKEEKEPKKEI-KKLPKDAKKSSTPLSEAKKPAALKPKVPKKEESVKKD 769
Query: 155 T--PGTPKKKETKKKFKLE 171
+ G PK+K K K E
Sbjct: 770 SVAAGKPKEKGKIKVIKKE 788
Score = 33.1 bits (74), Expect = 0.45
Identities = 26/95 (27%), Positives = 44/95 (46%), Gaps = 4/95 (4%)
Query: 296 DEKSETKK-QQKSDSEEKSDSEKKEDEEGKVGPGNHGTEGSGGERHSDTDSDRREDDRSQ 354
+E SET ++K+++EE + E+ +E V H ++ D+ RE S
Sbjct: 934 EESSETGDYEEKAETEEAEEPEEDGEEHVCVSASKHSPTEDEESAKAEADAYIREKRESV 993
Query: 355 HSSGNGNDFEM---ITKEELEQQTDGDCEEDEEEE 386
S + + +M I K E EQ + EED+ E+
Sbjct: 994 ASGDDRAEEDMDEAIEKGEAEQSEEEADEEDKAED 1028
Score = 31.2 bits (69), Expect = 1.7
Identities = 23/66 (34%), Positives = 32/66 (48%), Gaps = 2/66 (3%)
Query: 104 KDIKKE-KDKGKAESGKEEDKKSKKENIKDEKTKK-EKEKKKDGEKEESKKEETPGTPKK 161
K +KK+ K+K K + + K S D K+K K G KE S K +PKK
Sbjct: 2233 KALKKDLKEKTKTKKPGTKTKSSSPVKKSDGKSKPLAASPKPAGLKESSDKVSRVASPKK 2292
Query: 162 KETKKK 167
KE+ +K
Sbjct: 2293 KESVEK 2298
Score = 30.8 bits (68), Expect = 2.3
Identities = 14/43 (32%), Positives = 30/43 (69%), Gaps = 1/43 (2%)
Query: 103 DKDIKKEKDKGKAESGKEE-DKKSKKENIKDEKTKKEKEKKKD 144
++D+ + +KG+AE +EE D++ K E+ ++E+ + EK + +D
Sbjct: 1001 EEDMDEAIEKGEAEQSEEEADEEDKAEDAREEEYEPEKMEAED 1043
Score = 30.0 bits (66), Expect = 3.8
Identities = 14/38 (36%), Positives = 23/38 (60%)
Query: 287 KGPKADLKKDEKSETKKQQKSDSEEKSDSEKKEDEEGK 324
K K ++KK+EK E KK+ K ++ K ++ + EE K
Sbjct: 682 KEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKK 719
>gi|13540523 nucleosomal binding protein 1 [Homo sapiens]
Length = 282
Score = 53.5 bits (127), Expect = 3e-07
Identities = 36/116 (31%), Positives = 60/116 (51%), Gaps = 7/116 (6%)
Query: 284 HEYKGPKADLKKDEKSETK-KQQKSDSEEKSDSEKKEDEEGKVGPGNHGTEGSGGERHSD 342
+E KG KDEK E K+ K+ +E+ D+++KED GK G G G E+ D
Sbjct: 138 NEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKED--GKKGEDGKGNGEDGKEKGED 195
Query: 343 TDSDRREDDRSQHSSGNGNDFEMITKEELEQQTDGDCEEDEEEENDGETPKSSHEK 398
++ E+DR + G N+ + K + ++ D +EDE+E DG+ + +E+
Sbjct: 196 ---EKEEEDRKETGDGKENE-DGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEE 247
Score = 52.0 bits (123), Expect = 9e-07
Identities = 38/116 (32%), Positives = 62/116 (53%), Gaps = 9/116 (7%)
Query: 287 KGPKADLKKD-EKSETKKQQKSDSEEKSDSEKKEDEEGKVGPGNHGTEGSG-GERHSDTD 344
KG A K+D +K E K D +EK + EK+E++ + G G +G G++ D
Sbjct: 166 KGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKD 225
Query: 345 SDRREDDRSQHSSGN---GNDFEM-ITKEELEQQTDGDCEEDEEEENDG--ETPKS 394
+ED++ + GN+ E KE+L+++ +G EEDE +E+DG E P+S
Sbjct: 226 VKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGK-EEDEIKEDDGKKEEPQS 280
Score = 45.8 bits (107), Expect = 7e-05
Identities = 27/105 (25%), Positives = 52/105 (49%), Gaps = 12/105 (11%)
Query: 295 KDEKSETKKQQKSDSEEKSDSEKKE-DEEGKVGPGNHGTEGSGGERHSDTDSDRREDDRS 353
K+E+ + K+ ++ +EEK ++ K++ DE+G+ G E G + ++ + +
Sbjct: 124 KNEEEDQKEDEEDQNEEKGEAGKEDKDEKGE----EDGKEDKNGNEKGEDAKEKEDGKKG 179
Query: 354 QHSSGNGNDFEMITKEELEQQTDGDCEEDEEEENDGETPKSSHEK 398
+ GNG D + ++E E EED +E DG+ + EK
Sbjct: 180 EDGKGNGEDGKEKGEDEKE-------EEDRKETGDGKENEDGKEK 217
Score = 45.1 bits (105), Expect = 1e-04
Identities = 27/77 (35%), Positives = 49/77 (63%), Gaps = 5/77 (6%)
Query: 104 KDIKKEKDKGKAESGKE-EDKKSK--KENIKDEKTKKEKEKKKDGEKEESKKEETPGTPK 160
+D K+E+D+ + GKE ED K K K+ KD K K+++++++DG+++E EE G K
Sbjct: 194 EDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAG--K 251
Query: 161 KKETKKKFKLEPHDDQV 177
+KE K+ + +D++
Sbjct: 252 EKEDLKEEEEGKEEDEI 268
Score = 42.0 bits (97), Expect = 0.001
Identities = 32/89 (35%), Positives = 45/89 (50%), Gaps = 6/89 (6%)
Query: 101 KYDKDIKKEKDKGKAESGKE--EDKKSKKENIKDEKTKKE----KEKKKDGEKEESKKEE 154
K DKD K E+D + ++G E ED K K++ K E K KEK +D ++EE +KE
Sbjct: 146 KEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKET 205
Query: 155 TPGTPKKKETKKKFKLEPHDDQVFLDGNE 183
G + +K K E D +V D E
Sbjct: 206 GDGKENEDGKEKGDKKEGKDVKVKEDEKE 234
Score = 40.4 bits (93), Expect = 0.003
Identities = 21/58 (36%), Positives = 39/58 (67%), Gaps = 2/58 (3%)
Query: 101 KYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKE--KKKDGEKEESKKEETP 156
K KD+K ++D+ + E GKE++ +++E K+++ KE+E K++D KE+ K+E P
Sbjct: 221 KEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKKEEP 278
Score = 39.7 bits (91), Expect = 0.005
Identities = 26/82 (31%), Positives = 44/82 (53%), Gaps = 5/82 (6%)
Query: 104 KDIKKEKDKGKAESGKE--EDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGTPKK 161
+D K+++D K E GK ED K K E+ K+E+ +KE K+ E + K ++ G K
Sbjct: 168 EDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVK 227
Query: 162 KETKKKFKLEPHDDQVFLDGNE 183
+ +K + + +D+ GNE
Sbjct: 228 VKEDEKEREDGKEDE---GGNE 246
Score = 37.4 bits (85), Expect = 0.024
Identities = 25/84 (29%), Positives = 46/84 (54%), Gaps = 8/84 (9%)
Query: 104 KDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEK----EKKKDGEKEESKKEETPGTP 159
K+ ++++++ K E+GKE+ + +E+ K++K EK ++K+DG+K E K
Sbjct: 131 KEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGK 190
Query: 160 KKKETKKKFKLEPHDDQVFLDGNE 183
+K E +K E D + DG E
Sbjct: 191 EKGEDEK----EEEDRKETGDGKE 210
Score = 35.4 bits (80), Expect = 0.092
Identities = 21/65 (32%), Positives = 36/65 (55%), Gaps = 1/65 (1%)
Query: 103 DKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGTPKKK 162
+K +K++ +EED+K +E+ +EK + KE K D + EE KE+ G K +
Sbjct: 110 EKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDK-DEKGEEDGKEDKNGNEKGE 168
Query: 163 ETKKK 167
+ K+K
Sbjct: 169 DAKEK 173
Score = 35.0 bits (79), Expect = 0.12
Identities = 26/104 (25%), Positives = 49/104 (47%), Gaps = 13/104 (12%)
Query: 297 EKSETKKQQKSDSEEKSDSEKKEDEEGKVGPGNHGTEGSGGERHSDTDSDRREDDRSQHS 356
EK KK+ + + + ++KEDEE + + +G G+ D ++ E+D +
Sbjct: 110 EKGGEKKEAVAAEVKNEEEDQKEDEEDQ-----NEEKGEAGKEDKD---EKGEEDGKEDK 161
Query: 357 SGNGNDFEMITKEELEQQTDG-----DCEEDEEEENDGETPKSS 395
+GN + KE+ ++ DG D +E E+E + E K +
Sbjct: 162 NGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKET 205
Score = 35.0 bits (79), Expect = 0.12
Identities = 31/95 (32%), Positives = 48/95 (50%), Gaps = 13/95 (13%)
Query: 101 KYDKDIKKEKD-KGKAESGKE--EDKKSK---------KENIKDEKTKKEKEKKKDGEKE 148
K +D KK +D KG E GKE ED+K + KEN +D K K +K++ KD + +
Sbjct: 171 KEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKEN-EDGKEKGDKKEGKDVKVK 229
Query: 149 ESKKEETPGTPKKKETKKKFKLEPHDDQVFLDGNE 183
E +KE G + +++ E D + +G E
Sbjct: 230 EDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKE 264
Score = 32.0 bits (71), Expect = 1.0
Identities = 28/94 (29%), Positives = 51/94 (54%), Gaps = 12/94 (12%)
Query: 97 VMKMKYDKDIKKEKDK-GKAESGKEEDKKSKKENIKDEKTKKEKEKKK------DGEKEE 149
V++ Y+++ K + K +A + ++E + K+ENI+D T+K EKK+ E+E+
Sbjct: 71 VVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDA-TEKGGEKKEAVAAEVKNEEED 129
Query: 150 SKKEETPGTPKKKETKKKFKLEPHDDQVFLDGNE 183
K++E +K E K+ K E ++ DG E
Sbjct: 130 QKEDEEDQNEEKGEAGKEDKDEKGEE----DGKE 159
>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
[Homo sapiens]
Length = 1412
Score = 52.0 bits (123), Expect = 9e-07
Identities = 28/69 (40%), Positives = 40/69 (57%), Gaps = 3/69 (4%)
Query: 101 KYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKE---KEKKKDGEKEESKKEETPG 157
K + + + +K G E G + + KSKKE K +K KK+ KEKKK +K +K E+P
Sbjct: 1338 KDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPS 1397
Query: 158 TPKKKETKK 166
KKK+ KK
Sbjct: 1398 QKKKKKKKK 1406
Score = 36.2 bits (82), Expect = 0.054
Identities = 22/52 (42%), Positives = 33/52 (63%), Gaps = 7/52 (13%)
Query: 99 KMKYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKT---KKEKEKKKDGEK 147
K + K K++KDK K KE+ KK+KK + KD ++ KK+K+KKK E+
Sbjct: 1363 KKEKKKSDKRKKDKEK----KEKKKKAKKASTKDSESPSQKKKKKKKKTAEQ 1410
Score = 35.4 bits (80), Expect = 0.092
Identities = 26/81 (32%), Positives = 42/81 (51%), Gaps = 17/81 (20%)
Query: 99 KMKYDK---DIKKEKDKGK--AESGKEEDKKSKKENIK-----DEKTKKEKEKKKDGEKE 148
K K DK D+K++K KG ++ K+E ++ ++ + D+ K K++KK +K
Sbjct: 1313 KAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKR 1372
Query: 149 ESKKEETPGTPKKKETKKKFK 169
+ KE KKE KKK K
Sbjct: 1373 KKDKE-------KKEKKKKAK 1386
Score = 30.8 bits (68), Expect = 2.3
Identities = 39/154 (25%), Positives = 53/154 (34%), Gaps = 34/154 (22%)
Query: 48 IASKAVDCLLDSKW---------AKAKKGEEALFTTRESVVDYCNRLLKKQFFHRALKV- 97
+ S CLL W + K E L R+ VVD +K + R K+
Sbjct: 1215 LQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLS 1274
Query: 98 --MKMKYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKE------KEKK------K 143
KK+K G E G+ K K K++ KEKK
Sbjct: 1275 GDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGS 1334
Query: 144 DGEKEESKKEETPG----------TPKKKETKKK 167
G K+E ++E G PK K+ KKK
Sbjct: 1335 QGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKK 1368
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 52.0 bits (123), Expect = 9e-07
Identities = 28/69 (40%), Positives = 40/69 (57%), Gaps = 3/69 (4%)
Query: 101 KYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKE---KEKKKDGEKEESKKEETPG 157
K + + + +K G E G + + KSKKE K +K KK+ KEKKK +K +K E+P
Sbjct: 1377 KDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPS 1436
Query: 158 TPKKKETKK 166
KKK+ KK
Sbjct: 1437 QKKKKKKKK 1445
Score = 36.2 bits (82), Expect = 0.054
Identities = 22/52 (42%), Positives = 33/52 (63%), Gaps = 7/52 (13%)
Query: 99 KMKYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKT---KKEKEKKKDGEK 147
K + K K++KDK K KE+ KK+KK + KD ++ KK+K+KKK E+
Sbjct: 1402 KKEKKKSDKRKKDKEK----KEKKKKAKKASTKDSESPSQKKKKKKKKTAEQ 1449
Score = 35.4 bits (80), Expect = 0.092
Identities = 26/81 (32%), Positives = 42/81 (51%), Gaps = 17/81 (20%)
Query: 99 KMKYDK---DIKKEKDKGK--AESGKEEDKKSKKENIK-----DEKTKKEKEKKKDGEKE 148
K K DK D+K++K KG ++ K+E ++ ++ + D+ K K++KK +K
Sbjct: 1352 KAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKR 1411
Query: 149 ESKKEETPGTPKKKETKKKFK 169
+ KE KKE KKK K
Sbjct: 1412 KKDKE-------KKEKKKKAK 1425
Score = 30.8 bits (68), Expect = 2.3
Identities = 39/154 (25%), Positives = 53/154 (34%), Gaps = 34/154 (22%)
Query: 48 IASKAVDCLLDSKW---------AKAKKGEEALFTTRESVVDYCNRLLKKQFFHRALKV- 97
+ S CLL W + K E L R+ VVD +K + R K+
Sbjct: 1254 LQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLS 1313
Query: 98 --MKMKYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKE------KEKK------K 143
KK+K G E G+ K K K++ KEKK
Sbjct: 1314 GDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGS 1373
Query: 144 DGEKEESKKEETPG----------TPKKKETKKK 167
G K+E ++E G PK K+ KKK
Sbjct: 1374 QGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKK 1407
>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
[Homo sapiens]
Length = 1488
Score = 52.0 bits (123), Expect = 9e-07
Identities = 28/69 (40%), Positives = 40/69 (57%), Gaps = 3/69 (4%)
Query: 101 KYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKE---KEKKKDGEKEESKKEETPG 157
K + + + +K G E G + + KSKKE K +K KK+ KEKKK +K +K E+P
Sbjct: 1414 KDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPS 1473
Query: 158 TPKKKETKK 166
KKK+ KK
Sbjct: 1474 QKKKKKKKK 1482
Score = 36.2 bits (82), Expect = 0.054
Identities = 22/52 (42%), Positives = 33/52 (63%), Gaps = 7/52 (13%)
Query: 99 KMKYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKT---KKEKEKKKDGEK 147
K + K K++KDK K KE+ KK+KK + KD ++ KK+K+KKK E+
Sbjct: 1439 KKEKKKSDKRKKDKEK----KEKKKKAKKASTKDSESPSQKKKKKKKKTAEQ 1486
Score = 35.4 bits (80), Expect = 0.092
Identities = 26/81 (32%), Positives = 42/81 (51%), Gaps = 17/81 (20%)
Query: 99 KMKYDK---DIKKEKDKGK--AESGKEEDKKSKKENIK-----DEKTKKEKEKKKDGEKE 148
K K DK D+K++K KG ++ K+E ++ ++ + D+ K K++KK +K
Sbjct: 1389 KAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKR 1448
Query: 149 ESKKEETPGTPKKKETKKKFK 169
+ KE KKE KKK K
Sbjct: 1449 KKDKE-------KKEKKKKAK 1462
Score = 30.8 bits (68), Expect = 2.3
Identities = 39/154 (25%), Positives = 53/154 (34%), Gaps = 34/154 (22%)
Query: 48 IASKAVDCLLDSKW---------AKAKKGEEALFTTRESVVDYCNRLLKKQFFHRALKV- 97
+ S CLL W + K E L R+ VVD +K + R K+
Sbjct: 1291 LQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLS 1350
Query: 98 --MKMKYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKE------KEKK------K 143
KK+K G E G+ K K K++ KEKK
Sbjct: 1351 GDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGS 1410
Query: 144 DGEKEESKKEETPG----------TPKKKETKKK 167
G K+E ++E G PK K+ KKK
Sbjct: 1411 QGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKK 1444
>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b [Homo
sapiens]
Length = 1411
Score = 52.0 bits (123), Expect = 9e-07
Identities = 28/69 (40%), Positives = 40/69 (57%), Gaps = 3/69 (4%)
Query: 101 KYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKE---KEKKKDGEKEESKKEETPG 157
K + + + +K G E G + + KSKKE K +K KK+ KEKKK +K +K E+P
Sbjct: 1337 KDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPS 1396
Query: 158 TPKKKETKK 166
KKK+ KK
Sbjct: 1397 QKKKKKKKK 1405
Score = 36.2 bits (82), Expect = 0.054
Identities = 22/52 (42%), Positives = 33/52 (63%), Gaps = 7/52 (13%)
Query: 99 KMKYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKT---KKEKEKKKDGEK 147
K + K K++KDK K KE+ KK+KK + KD ++ KK+K+KKK E+
Sbjct: 1362 KKEKKKSDKRKKDKEK----KEKKKKAKKASTKDSESPSQKKKKKKKKTAEQ 1409
Score = 35.4 bits (80), Expect = 0.092
Identities = 26/81 (32%), Positives = 42/81 (51%), Gaps = 17/81 (20%)
Query: 99 KMKYDK---DIKKEKDKGK--AESGKEEDKKSKKENIK-----DEKTKKEKEKKKDGEKE 148
K K DK D+K++K KG ++ K+E ++ ++ + D+ K K++KK +K
Sbjct: 1312 KAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKR 1371
Query: 149 ESKKEETPGTPKKKETKKKFK 169
+ KE KKE KKK K
Sbjct: 1372 KKDKE-------KKEKKKKAK 1385
Score = 30.8 bits (68), Expect = 2.3
Identities = 39/154 (25%), Positives = 53/154 (34%), Gaps = 34/154 (22%)
Query: 48 IASKAVDCLLDSKW---------AKAKKGEEALFTTRESVVDYCNRLLKKQFFHRALKV- 97
+ S CLL W + K E L R+ VVD +K + R K+
Sbjct: 1214 LQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLS 1273
Query: 98 --MKMKYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKE------KEKK------K 143
KK+K G E G+ K K K++ KEKK
Sbjct: 1274 GDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGS 1333
Query: 144 DGEKEESKKEETPG----------TPKKKETKKK 167
G K+E ++E G PK K+ KKK
Sbjct: 1334 QGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKK 1367
>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a [Homo
sapiens]
Length = 1450
Score = 52.0 bits (123), Expect = 9e-07
Identities = 28/69 (40%), Positives = 40/69 (57%), Gaps = 3/69 (4%)
Query: 101 KYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKE---KEKKKDGEKEESKKEETPG 157
K + + + +K G E G + + KSKKE K +K KK+ KEKKK +K +K E+P
Sbjct: 1376 KDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPS 1435
Query: 158 TPKKKETKK 166
KKK+ KK
Sbjct: 1436 QKKKKKKKK 1444
Score = 36.2 bits (82), Expect = 0.054
Identities = 22/52 (42%), Positives = 33/52 (63%), Gaps = 7/52 (13%)
Query: 99 KMKYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKT---KKEKEKKKDGEK 147
K + K K++KDK K KE+ KK+KK + KD ++ KK+K+KKK E+
Sbjct: 1401 KKEKKKSDKRKKDKEK----KEKKKKAKKASTKDSESPSQKKKKKKKKTAEQ 1448
Score = 35.4 bits (80), Expect = 0.092
Identities = 26/81 (32%), Positives = 42/81 (51%), Gaps = 17/81 (20%)
Query: 99 KMKYDK---DIKKEKDKGK--AESGKEEDKKSKKENIK-----DEKTKKEKEKKKDGEKE 148
K K DK D+K++K KG ++ K+E ++ ++ + D+ K K++KK +K
Sbjct: 1351 KAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKR 1410
Query: 149 ESKKEETPGTPKKKETKKKFK 169
+ KE KKE KKK K
Sbjct: 1411 KKDKE-------KKEKKKKAK 1424
Score = 30.8 bits (68), Expect = 2.3
Identities = 39/154 (25%), Positives = 53/154 (34%), Gaps = 34/154 (22%)
Query: 48 IASKAVDCLLDSKW---------AKAKKGEEALFTTRESVVDYCNRLLKKQFFHRALKV- 97
+ S CLL W + K E L R+ VVD +K + R K+
Sbjct: 1253 LQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLS 1312
Query: 98 --MKMKYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKE------KEKK------K 143
KK+K G E G+ K K K++ KEKK
Sbjct: 1313 GDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGS 1372
Query: 144 DGEKEESKKEETPG----------TPKKKETKKK 167
G K+E ++E G PK K+ KKK
Sbjct: 1373 QGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKK 1406
>gi|11225260 DNA topoisomerase I [Homo sapiens]
Length = 765
Score = 51.6 bits (122), Expect = 1e-06
Identities = 34/96 (35%), Positives = 50/96 (52%), Gaps = 16/96 (16%)
Query: 104 KDIKKEKDKGKAESGKEEDKKSKKENIKDEKTK-------KEKEKKKDGEKEESKKEETP 156
K+ KKEKD+ K++ E K S+K++ + EKTK K K+K KD +KE+ K+E+
Sbjct: 36 KEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKHKDKHKDRDKEKRKEEKVR 95
Query: 157 GTPKKKETKKK---------FKLEPHDDQVFLDGNE 183
+ K K+K K EP DD F+ E
Sbjct: 96 ASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKE 131
Score = 37.7 bits (86), Expect = 0.018
Identities = 28/119 (23%), Positives = 53/119 (44%), Gaps = 25/119 (21%)
Query: 278 FRPLYTHEYKGPKADL----KKDEKSETKKQQKSDSEEKSDSEKKEDEEGKVGPGNHGTE 333
FR +H++K D K+ +K + +++ K + E DSEKK E+ K G+
Sbjct: 16 FRLNDSHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKT-KHKDGSS 74
Query: 334 GSGGERHSDTDSDRREDDRSQHSSGNGNDFEMITKEELEQQTDGDCEEDEEEENDGETP 392
++H D D ++R++++ + S GD + +E+EN +P
Sbjct: 75 EKHKDKHKDRDKEKRKEEKVRAS--------------------GDAKIKKEKENGFSSP 113
Score = 37.4 bits (85), Expect = 0.024
Identities = 24/72 (33%), Positives = 36/72 (50%), Gaps = 2/72 (2%)
Query: 95 LKVMKMKYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEE 154
+K +K D+D K K +++KK K E +D K KK K K KD K+ + +
Sbjct: 133 IKPLKRPRDEDDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKD--KKVPEPDN 190
Query: 155 TPGTPKKKETKK 166
PKK+E +K
Sbjct: 191 KKKKPKKEEEQK 202
Score = 36.2 bits (82), Expect = 0.054
Identities = 20/80 (25%), Positives = 39/80 (48%)
Query: 103 DKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGTPKKK 162
D K+K K + KE K+ +E K ++ + +KK EKE++K ++ K
Sbjct: 20 DSHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKHKD 79
Query: 163 ETKKKFKLEPHDDQVFLDGN 182
+ K + K + +++V G+
Sbjct: 80 KHKDRDKEKRKEEKVRASGD 99
Score = 36.2 bits (82), Expect = 0.054
Identities = 24/70 (34%), Positives = 33/70 (47%), Gaps = 10/70 (14%)
Query: 108 KEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGE----------KEESKKEETPG 157
KE K E+D K + IK E TKKEK++K + E K++ KK P
Sbjct: 130 KEDIKPLKRPRDEDDADYKPKKIKTEDTKKEKKRKLEEEEDGKLKKPKNKDKDKKVPEPD 189
Query: 158 TPKKKETKKK 167
KKK K++
Sbjct: 190 NKKKKPKKEE 199
Score = 35.4 bits (80), Expect = 0.092
Identities = 27/91 (29%), Positives = 38/91 (41%), Gaps = 18/91 (19%)
Query: 103 DKDIKKEKDKGKAESGKEED------------------KKSKKENIKDEKTKKEKEKKKD 144
D IKKEK+ G + + +D K+ + E+ D K KK K +
Sbjct: 99 DAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKEDIKPLKRPRDEDDADYKPKKIKTEDTK 158
Query: 145 GEKEESKKEETPGTPKKKETKKKFKLEPHDD 175
EK+ +EE G KK + K K K P D
Sbjct: 159 KEKKRKLEEEEDGKLKKPKNKDKDKKVPEPD 189
Score = 32.3 bits (72), Expect = 0.78
Identities = 24/74 (32%), Positives = 39/74 (52%), Gaps = 11/74 (14%)
Query: 105 DIKKEKDKGKAESGKEEDKKSKKEN-IKDEKTKKEKEKK-------KDGEKEESKKEET- 155
D + E D +S K +DK +E+ K+ K +K++EK KD EK+ +KE+T
Sbjct: 9 DSQIEADFRLNDSHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTK 68
Query: 156 --PGTPKKKETKKK 167
G+ +K + K K
Sbjct: 69 HKDGSSEKHKDKHK 82
Score = 31.2 bits (69), Expect = 1.7
Identities = 20/55 (36%), Positives = 30/55 (54%)
Query: 99 KMKYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKE 153
K K K ++E K K K++DKK + + K +K KKE+E+K +EE E
Sbjct: 159 KEKKRKLEEEEDGKLKKPKNKDKDKKVPEPDNKKKKPKKEEEQKWKWWEEERYPE 213
Score = 30.4 bits (67), Expect = 2.9
Identities = 19/71 (26%), Positives = 32/71 (45%), Gaps = 11/71 (15%)
Query: 339 RHSDTDSDR----------REDDRSQHSSGNGNDFEMITKE-ELEQQTDGDCEEDEEEEN 387
+H D DR ++ ++S+HS+ D E KE E + DG E+ +++
Sbjct: 23 KHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKHKDKHK 82
Query: 388 DGETPKSSHEK 398
D + K EK
Sbjct: 83 DRDKEKRKEEK 93
>gi|217035093 cyclic nucleotide gated channel alpha 1 isoform 1
[Homo sapiens]
Length = 759
Score = 51.2 bits (121), Expect = 2e-06
Identities = 29/87 (33%), Positives = 46/87 (52%), Gaps = 15/87 (17%)
Query: 103 DKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGTPKKK 162
D++ +++K K K + K +DK K + + +K KK+KEKKK EK + KKEE
Sbjct: 168 DQEPEEKKKKKKEKKSKSDDKNENKNDPEKKKKKKDKEKKKKEEKSKDKKEE-------- 219
Query: 163 ETKKKFKLEPHDDQVFLDGNEVYVWIY 189
E K+ ++P GN Y W++
Sbjct: 220 EKKEVVVIDP-------SGNTYYNWLF 239
Score = 29.6 bits (65), Expect = 5.0
Identities = 16/62 (25%), Positives = 33/62 (53%), Gaps = 7/62 (11%)
Query: 295 KDEKSETKKQQKSDSEEKSD--SEKKEDEEGKVGPGNHGTEGSGGERHSDTDSDRREDDR 352
KD++ E KK++K + + KSD +E K D E K + ++ + D++E+++
Sbjct: 167 KDQEPEEKKKKKKEKKSKSDDKNENKNDPEKK-----KKKKDKEKKKKEEKSKDKKEEEK 221
Query: 353 SQ 354
+
Sbjct: 222 KE 223
Score = 29.3 bits (64), Expect = 6.6
Identities = 14/37 (37%), Positives = 24/37 (64%), Gaps = 1/37 (2%)
Query: 287 KGPKADLKKDEKSET-KKQQKSDSEEKSDSEKKEDEE 322
K K+D K + K++ KK++K D E+K EK +D++
Sbjct: 181 KKSKSDDKNENKNDPEKKKKKKDKEKKKKEEKSKDKK 217
Score = 28.9 bits (63), Expect = 8.6
Identities = 14/40 (35%), Positives = 27/40 (67%), Gaps = 7/40 (17%)
Query: 292 DLKKDEKSETKKQQKSDSEEKSDSE-------KKEDEEGK 324
D + +EK + KK++KS S++K++++ KK+D+E K
Sbjct: 168 DQEPEEKKKKKKEKKSKSDDKNENKNDPEKKKKKKDKEKK 207
>gi|71143141 cyclic nucleotide gated channel alpha 1 isoform 2 [Homo
sapiens]
Length = 690
Score = 51.2 bits (121), Expect = 2e-06
Identities = 29/87 (33%), Positives = 46/87 (52%), Gaps = 15/87 (17%)
Query: 103 DKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGTPKKK 162
D++ +++K K K + K +DK K + + +K KK+KEKKK EK + KKEE
Sbjct: 99 DQEPEEKKKKKKEKKSKSDDKNENKNDPEKKKKKKDKEKKKKEEKSKDKKEE-------- 150
Query: 163 ETKKKFKLEPHDDQVFLDGNEVYVWIY 189
E K+ ++P GN Y W++
Sbjct: 151 EKKEVVVIDP-------SGNTYYNWLF 170
Score = 29.6 bits (65), Expect = 5.0
Identities = 16/62 (25%), Positives = 33/62 (53%), Gaps = 7/62 (11%)
Query: 295 KDEKSETKKQQKSDSEEKSD--SEKKEDEEGKVGPGNHGTEGSGGERHSDTDSDRREDDR 352
KD++ E KK++K + + KSD +E K D E K + ++ + D++E+++
Sbjct: 98 KDQEPEEKKKKKKEKKSKSDDKNENKNDPEKK-----KKKKDKEKKKKEEKSKDKKEEEK 152
Query: 353 SQ 354
+
Sbjct: 153 KE 154
Score = 29.3 bits (64), Expect = 6.6
Identities = 14/37 (37%), Positives = 24/37 (64%), Gaps = 1/37 (2%)
Query: 287 KGPKADLKKDEKSET-KKQQKSDSEEKSDSEKKEDEE 322
K K+D K + K++ KK++K D E+K EK +D++
Sbjct: 112 KKSKSDDKNENKNDPEKKKKKKDKEKKKKEEKSKDKK 148
Score = 28.9 bits (63), Expect = 8.6
Identities = 14/40 (35%), Positives = 27/40 (67%), Gaps = 7/40 (17%)
Query: 292 DLKKDEKSETKKQQKSDSEEKSDSE-------KKEDEEGK 324
D + +EK + KK++KS S++K++++ KK+D+E K
Sbjct: 99 DQEPEEKKKKKKEKKSKSDDKNENKNDPEKKKKKKDKEKK 138
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 50.8 bits (120), Expect = 2e-06
Identities = 25/69 (36%), Positives = 45/69 (65%)
Query: 99 KMKYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGT 158
K K K KE +K K + +E+ +K K++ K+E+ ++E+E++++ EKEE +KEE
Sbjct: 38 KEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRR 97
Query: 159 PKKKETKKK 167
KKK+ ++K
Sbjct: 98 KKKKKRRRK 106
Score = 48.5 bits (114), Expect = 1e-05
Identities = 23/84 (27%), Positives = 52/84 (61%)
Query: 93 RALKVMKMKYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKK 152
R K + + +K+ KK+ + + KEE++K +K K +K ++E+E++++ E+EE ++
Sbjct: 29 RKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEE 88
Query: 153 EETPGTPKKKETKKKFKLEPHDDQ 176
EE ++K+ KK+ + E +++
Sbjct: 89 EEKEEGRRRKKKKKRRRKEEEEEK 112
Score = 47.8 bits (112), Expect = 2e-05
Identities = 24/78 (30%), Positives = 48/78 (61%)
Query: 99 KMKYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGT 158
K K K + E+ + E+ +EE+K+ K++ + EK K++++KKK E E+ K++E
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60
Query: 159 PKKKETKKKFKLEPHDDQ 176
+K++ KKK + E +++
Sbjct: 61 KRKRKRKKKKEEEEREEE 78
Score = 47.0 bits (110), Expect = 3e-05
Identities = 23/67 (34%), Positives = 42/67 (62%)
Query: 101 KYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGTPK 160
K K +K K+K K + K++ K+++K K+E+ KK K K+K ++EE ++EE +
Sbjct: 25 KEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEE 84
Query: 161 KKETKKK 167
+KE ++K
Sbjct: 85 EKEEEEK 91
Score = 45.4 bits (106), Expect = 9e-05
Identities = 23/72 (31%), Positives = 46/72 (63%), Gaps = 1/72 (1%)
Query: 99 KMKYDKDIKKEKDKGKAESG-KEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPG 157
K K K+ +K K+K + E K + KK K+E ++E+ ++E+E+K++ EKEE ++ +
Sbjct: 42 KKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKK 101
Query: 158 TPKKKETKKKFK 169
++KE +++ K
Sbjct: 102 KRRRKEEEEEKK 113
Score = 45.1 bits (105), Expect = 1e-04
Identities = 22/69 (31%), Positives = 45/69 (65%), Gaps = 6/69 (8%)
Query: 99 KMKYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGT 158
K K + KKE+++ + E +EE++K ++E + + KK+K++++ E+EE KK+
Sbjct: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKK----- 115
Query: 159 PKKKETKKK 167
++++TKKK
Sbjct: 116 -RRRKTKKK 123
Score = 44.3 bits (103), Expect = 2e-04
Identities = 26/83 (31%), Positives = 47/83 (56%), Gaps = 2/83 (2%)
Query: 96 KVMKMKYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKE--KEKKKDGEKEESKKE 153
K K K + + +E ++ + E KE +K K++ + EK KK+ KE +K EKEE +K+
Sbjct: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61
Query: 154 ETPGTPKKKETKKKFKLEPHDDQ 176
KKKE +++ + E +++
Sbjct: 62 RKRKRKKKKEEEEREEEEEEEEE 84
Score = 42.4 bits (98), Expect = 7e-04
Identities = 23/84 (27%), Positives = 51/84 (60%), Gaps = 5/84 (5%)
Query: 96 KVMKMKYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEE-----S 150
K + + +K +KEK K E+ K ++K+ +++ K ++ KK++E++++ E+EE
Sbjct: 28 KRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKE 87
Query: 151 KKEETPGTPKKKETKKKFKLEPHD 174
++E+ G +KK+ K++ K E +
Sbjct: 88 EEEKEEGRRRKKKKKRRRKEEEEE 111
Score = 42.0 bits (97), Expect = 0.001
Identities = 25/97 (25%), Positives = 48/97 (49%), Gaps = 8/97 (8%)
Query: 302 KKQQKSDSEEKSDSEKKEDEEGKVGPGNHGTEGSGGERHSDTDSDRREDDRSQHSSGNGN 361
KK++K ++EE ++E+ E+EE K EG E+ + ++ + +++ +
Sbjct: 3 KKKKKKETEETEETEETEEEEEK--------EGKRKEKRKEKRKEKEKKKKTKETEKRKE 54
Query: 362 DFEMITKEELEQQTDGDCEEDEEEENDGETPKSSHEK 398
E K + +++ + EE EEEE + E K EK
Sbjct: 55 KEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEK 91
Score = 40.8 bits (94), Expect = 0.002
Identities = 17/71 (23%), Positives = 46/71 (64%)
Query: 99 KMKYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGT 158
K K ++ +K++ + + + +EE+++ ++E ++EK ++EKE+ + +K++ ++ +
Sbjct: 51 KRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEE 110
Query: 159 PKKKETKKKFK 169
KKK+ ++K K
Sbjct: 111 EKKKKRRRKTK 121
Score = 40.4 bits (93), Expect = 0.003
Identities = 20/73 (27%), Positives = 44/73 (60%)
Query: 103 DKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGTPKKK 162
+++ K+ K K K + ++E +K KK +++ +KE+E+KK K + KKEE +++
Sbjct: 21 EEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEE 80
Query: 163 ETKKKFKLEPHDD 175
E +++ + E ++
Sbjct: 81 EEEEEKEEEEKEE 93
Score = 38.9 bits (89), Expect = 0.008
Identities = 21/102 (20%), Positives = 50/102 (49%), Gaps = 5/102 (4%)
Query: 297 EKSETKKQQKSDSEEKSDSEKKEDEEGKVGPGNHGTEGSGGERHSDTDSDRREDDRSQHS 356
+K + KK++ ++EE ++E++E++EGK ++ ++++R++ +
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60
Query: 357 SGNGNDFEMITKEELEQQTDGDCEEDEEEENDGETPKSSHEK 398
+ +EE E++ EE+EEEE + E + +
Sbjct: 61 KRKRKRKKKKEEEEREEE-----EEEEEEEKEEEEKEEGRRR 97
Score = 37.7 bits (86), Expect = 0.018
Identities = 17/74 (22%), Positives = 45/74 (60%)
Query: 103 DKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGTPKKK 162
+++ +KE + + K ++K+ KK+ + EK K+++E++K +++ KK+E +++
Sbjct: 20 EEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEE 79
Query: 163 ETKKKFKLEPHDDQ 176
E +++ K E ++
Sbjct: 80 EEEEEEKEEEEKEE 93
Score = 36.2 bits (82), Expect = 0.054
Identities = 23/109 (21%), Positives = 50/109 (45%), Gaps = 4/109 (3%)
Query: 290 KADLKKDEKSETKKQQKSDSEEKSDSEKKEDEEGKVGPGNHGTEGSGGERHSDTDSDRRE 349
K KK E ET++ ++++ EE+ + ++KE + K E + ++ ++ E
Sbjct: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEK----RKEKEKKKKTKETEKRKEKEE 57
Query: 350 DDRSQHSSGNGNDFEMITKEELEQQTDGDCEEDEEEENDGETPKSSHEK 398
+++ + E +EE E++ + EE++EE + K K
Sbjct: 58 EEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRK 106
Score = 35.0 bits (79), Expect = 0.12
Identities = 18/68 (26%), Positives = 33/68 (48%)
Query: 287 KGPKADLKKDEKSETKKQQKSDSEEKSDSEKKEDEEGKVGPGNHGTEGSGGERHSDTDSD 346
K K K+ EK E +K++K ++K + E++E+EE + E G R
Sbjct: 44 KKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKR 103
Query: 347 RREDDRSQ 354
RR+++ +
Sbjct: 104 RRKEEEEE 111
Score = 34.3 bits (77), Expect = 0.20
Identities = 19/90 (21%), Positives = 44/90 (48%), Gaps = 1/90 (1%)
Query: 285 EYKGPKADLKKDEKSETKKQQKSDSEEKSDSEKKEDEEGKVGPGNHGTEGSGGERHSDTD 344
E +G + + +K+++ E +K++K+ EK EK+E+E+ + E E + +
Sbjct: 24 EKEGKRKEKRKEKRKEKEKKKKTKETEKR-KEKEEEEKKRKRKRKKKKEEEEREEEEEEE 82
Query: 345 SDRREDDRSQHSSGNGNDFEMITKEELEQQ 374
+ +E++ + + KEE E++
Sbjct: 83 EEEKEEEEKEEGRRRKKKKKRRRKEEEEEK 112
Score = 32.0 bits (71), Expect = 1.0
Identities = 24/112 (21%), Positives = 52/112 (46%), Gaps = 13/112 (11%)
Query: 287 KGPKADLKKDEKSETKKQQKSDSEEKSDSEKKEDEEGKVGPGNHGTEGSGGERHSDTDSD 346
K K + +E ET++ ++ + +E EK++ E+ K T+ + + + +
Sbjct: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRK-EKRKEKEKKKKTKETEKRKEKEEEEK 60
Query: 347 RREDDRSQHSSGNGNDFEMITKEELEQQTDGDCEEDEEEENDGETPKSSHEK 398
+R+ R + KEE E++ + + EE+E+EE + E + +K
Sbjct: 61 KRKRKRKK------------KKEEEEREEEEEEEEEEKEEEEKEEGRRRKKK 100
Score = 30.8 bits (68), Expect = 2.3
Identities = 15/70 (21%), Positives = 35/70 (50%)
Query: 283 THEYKGPKADLKKDEKSETKKQQKSDSEEKSDSEKKEDEEGKVGPGNHGTEGSGGERHSD 342
T + K + + KK ++ KK+++ + EE+ + E++E EE + G + R +
Sbjct: 49 TEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEE 108
Query: 343 TDSDRREDDR 352
+ +++ R
Sbjct: 109 EEEKKKKRRR 118
>gi|239750213 PREDICTED: hypothetical protein [Homo sapiens]
Length = 248
Score = 50.1 bits (118), Expect = 4e-06
Identities = 28/75 (37%), Positives = 41/75 (54%)
Query: 96 KVMKMKYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEET 155
K K K K+K K + KK+ K+++ +KEKEK+K+ EKE+ K++E
Sbjct: 39 KTTMKKKKKTTTKKKTTTKTKKRTTTTKKTTTTTTKEKEKEKEKEKEKEKEKEKEKEKEK 98
Query: 156 PGTPKKKETKKKFKL 170
KKK+ KKK KL
Sbjct: 99 KKKKKKKKKKKKKKL 113
Score = 45.8 bits (107), Expect = 7e-05
Identities = 36/100 (36%), Positives = 49/100 (49%), Gaps = 6/100 (6%)
Query: 93 RALKVMKMKYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTK----KEKEKKKDGEKE 148
R K K K K +K K K + K+ K+KK +KT KEKEK+K+ EKE
Sbjct: 27 RKKKTTKKKKKKKTTMKKKK-KTTTKKKTTTKTKKRTTTTKKTTTTTTKEKEKEKEKEKE 85
Query: 149 -ESKKEETPGTPKKKETKKKFKLEPHDDQVFLDGNEVYVW 187
E +KE+ KKK+ KKK K + + G E+ W
Sbjct: 86 KEKEKEKEKEKEKKKKKKKKKKKKKKKLNAKVCGLEIASW 125
Score = 40.4 bits (93), Expect = 0.003
Identities = 26/96 (27%), Positives = 46/96 (47%), Gaps = 3/96 (3%)
Query: 58 DSKWAKAKKGEEALFTTRESVVDYCNRLLKKQFFHRALKVMKMKYDKDIKKEKDKGKAES 117
+S W K+G + T ++ + KK + K KK E
Sbjct: 20 ESAW---KRGRKKKTTKKKKKKKTTMKKKKKTTTKKKTTTKTKKRTTTTKKTTTTTTKEK 76
Query: 118 GKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKE 153
KE++K+ +KE K+++ +KEK+KKK +K++ KK+
Sbjct: 77 EKEKEKEKEKEKEKEKEKEKEKKKKKKKKKKKKKKK 112
Score = 33.5 bits (75), Expect = 0.35
Identities = 23/65 (35%), Positives = 31/65 (47%), Gaps = 2/65 (3%)
Query: 103 DKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGTPKKK 162
DK + EK E + KK+ K +K KK KKK +K +KK+ T T K+
Sbjct: 5 DKGVAMEKVHVITEKESAWKRGRKKKTTKKKKKKKTTMKKK--KKTTTKKKTTTKTKKRT 62
Query: 163 ETKKK 167
T KK
Sbjct: 63 TTTKK 67
Score = 32.3 bits (72), Expect = 0.78
Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 4/75 (5%)
Query: 106 IKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESK----KEETPGTPKK 161
I +++ K K+ KK KK+ +K KK KKK K + + K+ T T K+
Sbjct: 16 ITEKESAWKRGRKKKTTKKKKKKKTTMKKKKKTTTKKKTTTKTKKRTTTTKKTTTTTTKE 75
Query: 162 KETKKKFKLEPHDDQ 176
KE +K+ + E ++
Sbjct: 76 KEKEKEKEKEKEKEK 90
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 49.7 bits (117), Expect = 5e-06
Identities = 22/67 (32%), Positives = 44/67 (65%)
Query: 101 KYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGTPK 160
K K+ ++++++ + E + E KK ++E ++ K +K++E+K+ GEKEE +KE+ K
Sbjct: 128 KEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERK 187
Query: 161 KKETKKK 167
K+E +K
Sbjct: 188 KRERNRK 194
Score = 47.0 bits (110), Expect = 3e-05
Identities = 26/81 (32%), Positives = 48/81 (59%), Gaps = 2/81 (2%)
Query: 87 KKQFFHRALKVMKMKYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGE 146
K++ + K + K +++ KK + + + + G+E++K+ KKE K E+ + KE K+
Sbjct: 78 KRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKE--KKERGRTSKEGKERER 135
Query: 147 KEESKKEETPGTPKKKETKKK 167
KEE K+EE +KKE ++K
Sbjct: 136 KEERKREERKERERKKEEREK 156
Score = 46.2 bits (108), Expect = 5e-05
Identities = 23/64 (35%), Positives = 40/64 (62%)
Query: 104 KDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGTPKKKE 163
K ++E++K K E KE ++ K+ K E+ K+E+E+KK ++E+K+ E KKKE
Sbjct: 60 KKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKE 119
Query: 164 TKKK 167
K++
Sbjct: 120 KKER 123
Score = 46.2 bits (108), Expect = 5e-05
Identities = 23/74 (31%), Positives = 43/74 (58%)
Query: 104 KDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGTPKKKE 163
K ++EK+ + E ++ KK KKE + K KE+E+K++ ++EE K+ E ++KE
Sbjct: 98 KKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKE 157
Query: 164 TKKKFKLEPHDDQV 177
++K + + QV
Sbjct: 158 RERKERKKRERKQV 171
Score = 45.8 bits (107), Expect = 7e-05
Identities = 42/165 (25%), Positives = 75/165 (45%), Gaps = 17/165 (10%)
Query: 3 ERRRHKKRIQEVGEPSKEEKAVAKYLRFNCPTKSTNMMGHRVDYFIASKAVDCLLDSKWA 62
ER+R + + ++ GE KEE+ K R + N G + + + SK
Sbjct: 76 ERKRERGKKEKKGERKKEERERKKRRR-----EKENKEGEEKEKRKKKEKKERGRTSKEG 130
Query: 63 KAKKGEEALFTTRESVVDYCNRLLKKQFFHRALKVMKMKYDKDIKKEKDKGKAESGKEED 122
K ++ +E R +K+ + + K + K+ KK + K E +E
Sbjct: 131 KERERKEER-----------KREERKERERKKEEREKERERKERKKRERKQVGEKEEERK 179
Query: 123 KKSKKENIKDEKTKKEKEKKKD-GEKEESKKEETPGTPKKKETKK 166
+K +KE K E+ +KE++K+++ E+ E KKE +KKE +K
Sbjct: 180 EKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQK 224
Score = 45.4 bits (106), Expect = 9e-05
Identities = 17/60 (28%), Positives = 41/60 (68%)
Query: 107 KKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGTPKKKETKK 166
+K++++ + E KE ++K ++E K+ K K+E++K++ +++ + +E+ G ++KE KK
Sbjct: 186 RKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
Score = 45.1 bits (105), Expect = 1e-04
Identities = 23/73 (31%), Positives = 46/73 (63%), Gaps = 1/73 (1%)
Query: 99 KMKYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGT 158
K + ++ +KE+++ K E KE ++K +K+ + + +KE E++K+ E++E KK E
Sbjct: 136 KEERKREERKERERKKEEREKERERKERKKRERKQVGEKE-EERKEKERKERKKRERNRK 194
Query: 159 PKKKETKKKFKLE 171
+KKE ++K + E
Sbjct: 195 ERKKERERKERRE 207
Score = 44.3 bits (103), Expect = 2e-04
Identities = 27/80 (33%), Positives = 46/80 (57%), Gaps = 4/80 (5%)
Query: 99 KMKYDKDIKKEKDKG--KAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETP 156
K + +K+ K+E+ K K E KEE ++ K+ K+ K +EKEK+K EK+E +
Sbjct: 70 KREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKE 129
Query: 157 GTPKKKETKKKFKLEPHDDQ 176
G K++E K++ K E ++
Sbjct: 130 G--KERERKEERKREERKER 147
Score = 42.0 bits (97), Expect = 0.001
Identities = 21/70 (30%), Positives = 43/70 (61%), Gaps = 1/70 (1%)
Query: 101 KYDKDIKKEKDKGKAESGKEE-DKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGTP 159
K +++ +++K++ + E K E +K+ K+E K EK + K+++++ +K +KE G
Sbjct: 52 KKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEE 111
Query: 160 KKKETKKKFK 169
K+K KK+ K
Sbjct: 112 KEKRKKKEKK 121
Score = 40.8 bits (94), Expect = 0.002
Identities = 26/114 (22%), Positives = 53/114 (46%), Gaps = 5/114 (4%)
Query: 285 EYKGPKADLKKDEKSETKKQQKSDSEEKSDSEKKEDEEGKVGPGNHGTEGSGGERHSDTD 344
E KG + +++ K ++++ + EEK +KKE +E G EG ER +
Sbjct: 85 EKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKE----RGRTSKEGKERERKEERK 140
Query: 345 SDRREDDRSQHSSGNGNDFEMITKEELEQQTDGDCEEDEEEENDGETPKSSHEK 398
+ R+ +R + + E +++ E++ G+ EE+ +E+ E K +
Sbjct: 141 REERK-ERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNR 193
Score = 37.7 bits (86), Expect = 0.018
Identities = 17/70 (24%), Positives = 45/70 (64%), Gaps = 1/70 (1%)
Query: 107 KKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGTPKKKETKK 166
++E++ + GK+E ++S+++ + E+ K+++E++K+ ++E KKE+ K++ +K
Sbjct: 40 EREREIETRKEGKKE-RESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERK 98
Query: 167 KFKLEPHDDQ 176
K + E + +
Sbjct: 99 KRRREKENKE 108
Score = 35.0 bits (79), Expect = 0.12
Identities = 21/104 (20%), Positives = 48/104 (46%), Gaps = 15/104 (14%)
Query: 290 KADLKKDEKSETKKQQKSDSEEKSDSEKKEDEEGKVGPGNHGTEGSGGERHSDTDSDRRE 349
K + K++E+ E +++++ +E+ E+K+ E +VG + + +R+E
Sbjct: 136 KEERKREERKERERKKEEREKERERKERKKRERKQVG---------------EKEEERKE 180
Query: 350 DDRSQHSSGNGNDFEMITKEELEQQTDGDCEEDEEEENDGETPK 393
+R + N E + E +++ + E ++EE E K
Sbjct: 181 KERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQK 224
Score = 32.7 bits (73), Expect = 0.59
Identities = 19/61 (31%), Positives = 31/61 (50%), Gaps = 2/61 (3%)
Query: 294 KKDEKSETKKQQKSDSEEKSDSEKKEDEEGKVGPGNHGTEGSGGERHSDTDSDRREDDRS 353
K+ E+ E KK++++ E K + E+KE E K E ER D ++ RE +R
Sbjct: 179 KEKERKERKKRERNRKERKKERERKERRERK--KERKKKEERKKERQKDRQTNWREKERG 236
Query: 354 Q 354
+
Sbjct: 237 K 237
Score = 32.3 bits (72), Expect = 0.78
Identities = 29/119 (24%), Positives = 53/119 (44%), Gaps = 16/119 (13%)
Query: 294 KKDEKSETKKQQKSDSE-----EKSDSEKKEDEEGKVGPGNHGTEGSGGERHSDTDSDRR 348
+++ + ET+K+ K + E E+ + EK++ E K G + GER + R
Sbjct: 40 EREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKK--EERER 97
Query: 349 EDDRSQHSSGNGNDFEMITKEELEQ--QTDGDCEEDE-------EEENDGETPKSSHEK 398
+ R + + G + E K+E ++ +T + +E E EE + E K EK
Sbjct: 98 KKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREK 156
Score = 30.4 bits (67), Expect = 2.9
Identities = 24/129 (18%), Positives = 49/129 (37%), Gaps = 17/129 (13%)
Query: 287 KGPKADLKKDEKSETKKQQKSDSEEKSDSEKKE-----------------DEEGKVGPGN 329
K +++ KK+ + K++++ + E K + KKE ++E K G
Sbjct: 53 KERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEK 112
Query: 330 HGTEGSGGERHSDTDSDRREDDRSQHSSGNGNDFEMITKEELEQQTDGDCEEDEEEENDG 389
+ + T + +E +R + KEE E++ + + E + G
Sbjct: 113 EKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVG 172
Query: 390 ETPKSSHEK 398
E + EK
Sbjct: 173 EKEEERKEK 181
>gi|151301171 RNA polymerase II transcription factor TAFII140 [Homo
sapiens]
Length = 929
Score = 49.3 bits (116), Expect = 6e-06
Identities = 27/65 (41%), Positives = 43/65 (66%), Gaps = 6/65 (9%)
Query: 108 KEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGTPKKKETKKK 167
+EK+K K E K++DKK KK+ + EK KKEKE++K+ + E +++E K+K +K
Sbjct: 691 EEKEKVK-EKEKKKDKKEKKKKKEKEKEKKEKEREKEKREREKREKE-----KEKHKHEK 744
Query: 168 FKLEP 172
K+EP
Sbjct: 745 IKVEP 749
Score = 42.4 bits (98), Expect = 7e-04
Identities = 33/135 (24%), Positives = 62/135 (45%), Gaps = 9/135 (6%)
Query: 50 SKAVDCLLDSKWAKAKKGEEAL------FTTRESVVDYCNRLLKKQFFHRALKVMKMKYD 103
S +D +D KAK G + + + SV L K + + ++
Sbjct: 463 SWTMDASIDEVVRKAKLGTPSNMPPNFPYISSPSVSPPTPEPLHKVYEEKTKLPSSVEVK 522
Query: 104 KDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGTPKKKE 163
K +KKE + K+ D++ +K+ KD+ +K+K K+K+ +KE ++ + P KE
Sbjct: 523 KKLKKELKTKMKKKEKQRDREREKDKNKDKSKEKDKVKEKEKDKETGRETKYPWKEFLKE 582
Query: 164 TKK---KFKLEPHDD 175
+ KFK++ +D
Sbjct: 583 EEADPYKFKIKEFED 597
Score = 42.4 bits (98), Expect = 7e-04
Identities = 28/95 (29%), Positives = 47/95 (49%), Gaps = 1/95 (1%)
Query: 63 KAKKGEEALFTTRESVVDYCNRLLKKQFFHRALKVMKMK-YDKDIKKEKDKGKAESGKEE 121
K K+ E+ T RE+ + L +++ K+ + + D +K + + E K +
Sbjct: 558 KVKEKEKDKETGRETKYPWKEFLKEEEADPYKFKIKEFEDVDPKVKLKDGLVRKEKEKHK 617
Query: 122 DKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETP 156
DKK +E K +K K+EKEK KD +E+ K P
Sbjct: 618 DKKKDREKGKKDKDKREKEKVKDKGREDKMKAPAP 652
Score = 40.4 bits (93), Expect = 0.003
Identities = 21/49 (42%), Positives = 32/49 (65%), Gaps = 1/49 (2%)
Query: 126 KKENIKD-EKTKKEKEKKKDGEKEESKKEETPGTPKKKETKKKFKLEPH 173
+KE +K+ EK K +KEKKK EKE+ KKE+ K++ K++ + E H
Sbjct: 692 EKEKVKEKEKKKDKKEKKKKKEKEKEKKEKEREKEKREREKREKEKEKH 740
Score = 39.3 bits (90), Expect = 0.006
Identities = 26/70 (37%), Positives = 43/70 (61%), Gaps = 5/70 (7%)
Query: 85 LLKKQFFHRALKVMKMKYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKD 144
+L ++ F KV + + KD KKEK K K KE++KK +KE K+++ ++++EK+K+
Sbjct: 684 VLPEKLFEEKEKVKEKEKKKD-KKEKKKKKE---KEKEKK-EKEREKEKREREKREKEKE 738
Query: 145 GEKEESKKEE 154
K E K E
Sbjct: 739 KHKHEKIKVE 748
Score = 37.0 bits (84), Expect = 0.031
Identities = 40/164 (24%), Positives = 64/164 (39%), Gaps = 51/164 (31%)
Query: 96 KVMKMKYDKDIKKEKDKGKAESGKEEDKKSKKEN-------------------------- 129
K+ K + +D ++EKDK K +S KE+DK +KE
Sbjct: 532 KMKKKEKQRDREREKDKNKDKS-KEKDKVKEKEKDKETGRETKYPWKEFLKEEEADPYKF 590
Query: 130 -------------IKDEKTKKEKEKKKD-------GEKEESKKEETPGTPKKKETKKKFK 169
+KD +KEKEK KD G+K++ K+E+ K +E K K
Sbjct: 591 KIKEFEDVDPKVKLKDGLVRKEKEKHKDKKKDREKGKKDKDKREKEKVKDKGREDKMKAP 650
Query: 170 LEPHDDQVFLDGNEVYVWIYDPVHFKTFVMGLILVIAVIAATLF 213
P + L E+ + ++ P L ++ V+ LF
Sbjct: 651 APP----LVLPPKELALPLFSPATASRVPAMLPSLLPVLPEKLF 690
Score = 35.8 bits (81), Expect = 0.070
Identities = 21/41 (51%), Positives = 29/41 (70%), Gaps = 2/41 (4%)
Query: 128 ENIKDEKTK-KEKEKKKDGEKEESKKEETPGTPKKKETKKK 167
E + +EK K KEKEKKKD +KE+ KK+E K+KE +K+
Sbjct: 687 EKLFEEKEKVKEKEKKKD-KKEKKKKKEKEKEKKEKEREKE 726
Score = 32.7 bits (73), Expect = 0.59
Identities = 27/82 (32%), Positives = 40/82 (48%), Gaps = 13/82 (15%)
Query: 107 KKEKDKGKAESGKEEDKKSKKENIKDEKTK-KEKEKKKDGEKEESKKEETPGTPKKKETK 165
K ++K K S E KK KKE KTK K+KEK++D E+E+ K K ++K
Sbjct: 507 KVYEEKTKLPSSVEVKKKLKKEL----KTKMKKKEKQRDREREKDKN--------KDKSK 554
Query: 166 KKFKLEPHDDQVFLDGNEVYVW 187
+K K++ + Y W
Sbjct: 555 EKDKVKEKEKDKETGRETKYPW 576
Score = 32.3 bits (72), Expect = 0.78
Identities = 15/40 (37%), Positives = 25/40 (62%)
Query: 285 EYKGPKADLKKDEKSETKKQQKSDSEEKSDSEKKEDEEGK 324
E K K + KK ++ E +K++K +EK + EK+E E+ K
Sbjct: 700 EKKKDKKEKKKKKEKEKEKKEKEREKEKREREKREKEKEK 739
Score = 30.4 bits (67), Expect = 2.9
Identities = 14/50 (28%), Positives = 28/50 (56%)
Query: 275 IDSFRPLYTHEYKGPKADLKKDEKSETKKQQKSDSEEKSDSEKKEDEEGK 324
+ S P+ + K +K+ EK + KK++K E++ + ++KE E+ K
Sbjct: 678 LPSLLPVLPEKLFEEKEKVKEKEKKKDKKEKKKKKEKEKEKKEKEREKEK 727
Score = 30.4 bits (67), Expect = 2.9
Identities = 13/44 (29%), Positives = 27/44 (61%)
Query: 281 LYTHEYKGPKADLKKDEKSETKKQQKSDSEEKSDSEKKEDEEGK 324
L+ + K + + KKD+K + KK++K +++ + EK++ E K
Sbjct: 689 LFEEKEKVKEKEKKKDKKEKKKKKEKEKEKKEKEREKEKREREK 732
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 49.3 bits (116), Expect = 6e-06
Identities = 28/99 (28%), Positives = 50/99 (50%), Gaps = 3/99 (3%)
Query: 295 KDEKSETKKQQKSDSEEKSDSEKKEDEEGKVGPGNHGTEGSGGERHSDTDSDRREDDRSQ 354
++E+ E + +++ + EE+ + E +E+EEG+V G EG G + + + E ++
Sbjct: 991 EEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEG 1050
Query: 355 HSSGNGNDFEMITKEELEQQTDGDCEEDEEEENDGETPK 393
N + E +EE + Q G E+E E DGE K
Sbjct: 1051 EGEENRRNREEEEEEEGKYQETG---EEENERQDGEEYK 1086
Score = 47.8 bits (112), Expect = 2e-05
Identities = 30/104 (28%), Positives = 46/104 (44%), Gaps = 1/104 (0%)
Query: 295 KDEKSETKKQQKSDSEEKSDSEKKEDEEGKVGPGNHGTEGSGGERHSDTDSDRREDD-RS 353
K+EK E + Q EE+++ +E EEG G EG G + + + E++
Sbjct: 783 KEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEG 842
Query: 354 QHSSGNGNDFEMITKEELEQQTDGDCEEDEEEENDGETPKSSHE 397
+ G G + E K E E + EE EE E +GE + E
Sbjct: 843 EEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGE 886
Score = 45.1 bits (105), Expect = 1e-04
Identities = 32/121 (26%), Positives = 58/121 (47%), Gaps = 14/121 (11%)
Query: 285 EYKGPKADLKKDEKSETKKQQKSDSEEKSDSEKK---EDEEGKVGPGNHGTEGSGGERHS 341
E +G + + K E+ E +++ + + EE E++ E+EEG+ G EG G E
Sbjct: 813 EVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGE 872
Query: 342 DTDSDRREDDRSQHSSGNGNDFEMITKEELEQQTDGDCEED-----EEEENDGETPKSSH 396
+ + + E++ G G E E E++ +G+ EE+ EEEE +G+ +
Sbjct: 873 EGEGEGEEEE------GEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGE 926
Query: 397 E 397
E
Sbjct: 927 E 927
Score = 43.9 bits (102), Expect = 3e-04
Identities = 31/102 (30%), Positives = 49/102 (48%), Gaps = 12/102 (11%)
Query: 297 EKSETKKQQKSDSEEKSDSEKKEDEEGKVGPGNHG-TEGSGGERHSDTDSDRREDDRSQH 355
E K++ + EE++ E+K +EEG G G TEG G E+ + + E +
Sbjct: 765 EGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEE--- 821
Query: 356 SSGNGNDFEMITKEELEQQTDGDCEEDEEEENDGETPKSSHE 397
G G +EE E++ +G+ EE E EE +GE + E
Sbjct: 822 --GKGE------REEEEEEGEGEEEEGEGEEEEGEGEEEEGE 855
Score = 43.5 bits (101), Expect = 3e-04
Identities = 30/101 (29%), Positives = 47/101 (46%), Gaps = 5/101 (4%)
Query: 297 EKSETKKQQKSDSEEKSDSEKKEDEEGKVGPGNHGTEGSGGERHSDTDSDRREDDRSQHS 356
E +E ++ +K D EE+ E+KE E+G N E G E H + + E DR +
Sbjct: 695 ELAEKEEWKKRDGEEQ---EQKEREQGHQKERNQEMEEGGEEEHG--EGEEEEGDREEEE 749
Query: 357 SGNGNDFEMITKEELEQQTDGDCEEDEEEENDGETPKSSHE 397
G E EE+E + + + E ++EE G+ K E
Sbjct: 750 EKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEE 790
Score = 43.5 bits (101), Expect = 3e-04
Identities = 31/119 (26%), Positives = 55/119 (46%), Gaps = 7/119 (5%)
Query: 285 EYKGPKADLKKDEKSETKKQQKSDSE---EKSDSEKKEDEEGKVGPGNHGTE---GSGGE 338
E KG + + +++ + E ++ + + E E+ + E K +EEG+ G G E G G E
Sbjct: 821 EGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEE 880
Query: 339 RHSDTDSDRREDDRSQHSSGNGNDFEMITKEELEQQTDGDCEEDEEEENDGETPKSSHE 397
+ + + + + G G E E E++ +G EE E EE +GE + E
Sbjct: 881 EEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEE-EGEEGEGEGEEEEGE 938
Score = 43.1 bits (100), Expect = 4e-04
Identities = 28/114 (24%), Positives = 52/114 (45%), Gaps = 1/114 (0%)
Query: 285 EYKGPKADLKKDEKSETKKQQKSDSEEKSDSEKKEDEEGKVGPGNHGTEGSGGERHSDTD 344
E +G D + + + E + + + E + + E++ + EG+ G G E GE +
Sbjct: 936 EGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEG 995
Query: 345 SDRREDDRSQHSSGNGNDFEMITKEELEQQTDGDCEEDEEEENDGETPKSSHEK 398
+ E++ G G + E + E+E + +G+ E E EE +GE EK
Sbjct: 996 EEEGEEEGEGEEEGEG-EGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREK 1048
Score = 42.7 bits (99), Expect = 6e-04
Identities = 28/117 (23%), Positives = 53/117 (45%), Gaps = 7/117 (5%)
Query: 287 KGPKADLKKDEKSETKKQQKSDSEEKSDSEKKEDEEGKVGPGNHGTEGSG------GERH 340
+G + + ++ + +++ EE+ D E++E++EG+ G E G GER
Sbjct: 717 QGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERK 776
Query: 341 SDTDSDRREDDRSQHSSGNGNDFEMITKEELEQQTDGDCEEDEEEENDGETPKSSHE 397
+ + + E + G G + E + E E++ G+ E E EE GE + E
Sbjct: 777 KEERAGKEEKGEEEGDQGEGEEEETEGRGE-EKEEGGEVEGGEVEEGKGEREEEEEE 832
Score = 42.0 bits (97), Expect = 0.001
Identities = 30/114 (26%), Positives = 53/114 (46%), Gaps = 10/114 (8%)
Query: 294 KKDEKSETKKQQKSDSEEKSDSE------KKEDEEGKVGPGNHGTEGSGGERHSDTDSDR 347
++ E+ E KK++++ EEK + E ++E+ EG+ G E GGE
Sbjct: 768 REKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGERE 827
Query: 348 REDDRSQHSSGNGNDFEMITKEELEQQTDGDCEEDEEE---ENDGETPKSSHEK 398
E++ + G E + E E++ +G EE+ EE E +GE + E+
Sbjct: 828 EEEEEGEGEEEEGEGEEEEGEGE-EEEGEGKGEEEGEEGEGEEEGEEGEGEGEE 880
Score = 42.0 bits (97), Expect = 0.001
Identities = 28/114 (24%), Positives = 50/114 (43%), Gaps = 7/114 (6%)
Query: 285 EYKGPKADLKKDEKSETKKQQKSDSEEKSDSEKKEDEEGKVGPGNHGTEGSGGERHSDTD 344
E +G + + + K E + ++ EE + E + +EE G G EG G E + +
Sbjct: 844 EEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGE 903
Query: 345 SDRREDDRSQHSSGNGNDFEMITKEELEQQTDGDCEEDEEEENDGETPKSSHEK 398
+ + + G G EE ++ +G+ EE EE E +GE + E+
Sbjct: 904 GEEEGEGEGEEEEGEGKG------EEEGEEGEGEGEE-EEGEGEGEDGEGEGEE 950
Score = 42.0 bits (97), Expect = 0.001
Identities = 32/111 (28%), Positives = 53/111 (47%), Gaps = 8/111 (7%)
Query: 285 EYKGPKADLKKDEKSETKKQQKSDSEEKSDSEKKEDEEGKVGPGNHGTEGSGGERHSDTD 344
E +G + + E E + + K + E + + E+EEG+ G G G EG G E + +
Sbjct: 899 EGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGE-GEGEDG-EGEGEEEEGEWE 956
Query: 345 SDRREDDRSQHSSGNGNDFEMITKEELEQQTDGDCEEDE-----EEENDGE 390
+ E + G G E + E E++ +G+ EE+E EEE +GE
Sbjct: 957 GEEEEGEGEGEEEGEGEGEEGEGEGE-EEEGEGEGEEEEGEEEGEEEGEGE 1006
Score = 41.2 bits (95), Expect = 0.002
Identities = 31/116 (26%), Positives = 58/116 (50%), Gaps = 13/116 (11%)
Query: 290 KADLKKDEKSETKKQQKSDSEE------KSDSE-KKEDEEGKVGPGNHGTEGSGGERHSD 342
+ D +++E+ E + +++ + EE K + E KKE+ GK G EG GE +
Sbjct: 742 EGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEE--EGDQGEGEEE 799
Query: 343 TDSDRREDDRSQHSSGNGNDFEMITKEELEQQTDGDCEEDEEEENDGETPKSSHEK 398
+++ R +++ + G + E E E++ +G E EEEE +GE + E+
Sbjct: 800 -ETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEG---EGEEEEGEGEEEEGEGEE 851
Score = 41.2 bits (95), Expect = 0.002
Identities = 18/54 (33%), Positives = 37/54 (68%)
Query: 110 KDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGTPKKKE 163
K++G+ E + E +K + E K+E+ KE++ +++G++ E ++EET G ++KE
Sbjct: 756 KEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKE 809
Score = 39.7 bits (91), Expect = 0.005
Identities = 32/129 (24%), Positives = 56/129 (43%), Gaps = 15/129 (11%)
Query: 285 EYKGPKADLKKDEKSETKKQQKSDSEEKSDSEKK----------EDEEGKVGPGNHGTEG 334
E K +++ E E K +++ + EE E++ E+EEG+ G EG
Sbjct: 806 EEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEG 865
Query: 335 SGGE--RHSDTDSDRREDDRSQHSSGNGNDFEMITKEELEQQTDGDCEEDEEE---ENDG 389
G E + + + E + G G E + E E++ +G+ EE+E E E +G
Sbjct: 866 EGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEG 925
Query: 390 ETPKSSHEK 398
E + E+
Sbjct: 926 EEGEGEGEE 934
Score = 39.3 bits (90), Expect = 0.006
Identities = 35/127 (27%), Positives = 58/127 (45%), Gaps = 15/127 (11%)
Query: 285 EYKGPKADLKKDEKSETKKQQKSDSEEKSDSEKKEDEEGK------VGPGNHGTEGSG-- 336
E KG + + + + E ++ + EE+ + E +E+ EG+ G G EG G
Sbjct: 855 EGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEE 914
Query: 337 --GERHSDTDSDRRE-DDRSQHSSGNGNDFEMITKEELEQQTDGDCEEDE---EEENDGE 390
GE + + + E + + G G D E +EE E + +G+ EE E EEE +GE
Sbjct: 915 EEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEE-EGEWEGEEEEGEGEGEEEGEGE 973
Query: 391 TPKSSHE 397
+ E
Sbjct: 974 GEEGEGE 980
Score = 38.9 bits (89), Expect = 0.008
Identities = 31/111 (27%), Positives = 53/111 (47%), Gaps = 11/111 (9%)
Query: 295 KDEKSETKKQQKSDSEEKSDSEKKEDEEGKVGPGNHGT----EGSGGERH-SDTDSDRRE 349
+ EK+E +D E S+ + K E + GP G EGS G H D + ++ E
Sbjct: 619 RKEKTEILSDDLTDKAEVSEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGE 678
Query: 350 DDRSQ---HSSGNGNDFEMITKEELEQQTDGDCEEDEEEENDGETPKSSHE 397
D+ + G G E+ KEE +++ DG+ E++++E G + + E
Sbjct: 679 KDKGRGEMERPGEGEK-ELAEKEEWKKR-DGE-EQEQKEREQGHQKERNQE 726
Score = 38.9 bits (89), Expect = 0.008
Identities = 28/105 (26%), Positives = 50/105 (47%), Gaps = 4/105 (3%)
Query: 295 KDEKSETKKQQKSDSE-EKSDSEKKEDEEGKVGPGNHGTEGSGGERHSDTDSDRREDDRS 353
++E+ E + +++ + E E+ + E K +EEG+ G G E GE D + ++
Sbjct: 896 EEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGE---DGEGEGEEEE 952
Query: 354 QHSSGNGNDFEMITKEELEQQTDGDCEEDEEEENDGETPKSSHEK 398
G + E +EE E + + E EEEE +GE + E+
Sbjct: 953 GEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEE 997
Score = 38.5 bits (88), Expect = 0.011
Identities = 26/74 (35%), Positives = 45/74 (60%), Gaps = 4/74 (5%)
Query: 107 KKEKDKGKAESGKEEDKKSKKEN-IKDEKTKKEKEKKKDGEKE--ESKKEETPGTPKKKE 163
+KE+++ E G+EE + ++E ++E+ +KE E K++GE E E ++E+ G KK+E
Sbjct: 720 QKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEE 779
Query: 164 -TKKKFKLEPHDDQ 176
K+ K E DQ
Sbjct: 780 RAGKEEKGEEEGDQ 793
Score = 38.1 bits (87), Expect = 0.014
Identities = 27/109 (24%), Positives = 54/109 (49%), Gaps = 9/109 (8%)
Query: 295 KDEKSETKKQQKSDSE-EKSDSEKKEDEEGKVGPGNHGTEGSGGERHSDTDSDRREDDRS 353
++E+ E + +++ + E E+ + E + +EEG+ EG G E + + + E++
Sbjct: 879 EEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEE-- 936
Query: 354 QHSSGNGNDFEMITKEELEQ----QTDGDCEEDEEEENDGETPKSSHEK 398
G G D E +EE + + +G+ E +EE E +GE + E+
Sbjct: 937 --GEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEE 983
Score = 37.0 bits (84), Expect = 0.031
Identities = 29/119 (24%), Positives = 53/119 (44%), Gaps = 8/119 (6%)
Query: 285 EYKGPKADLKKDEKSETKKQQKSDSEEKSDSEKKEDEEGK------VGPGNHGTEGSGGE 338
E +G + + + + + E + + + + E E+ E+ EG+ G G G EG G E
Sbjct: 892 EGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDG-EGEGEE 950
Query: 339 RHSDTDSDRREDDRSQHSSGNGNDFEMITKEELEQQTDGDCEEDEEEENDGETPKSSHE 397
+ + + E + G G E + E E++ +G+ EE+E EE E + E
Sbjct: 951 EEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGE-EEEGEGEGEEEEGEEEGEEEGEGEEE 1008
Score = 37.0 bits (84), Expect = 0.031
Identities = 26/107 (24%), Positives = 47/107 (43%), Gaps = 1/107 (0%)
Query: 285 EYKGPKADLKKDEKSETKKQQKSDSEEKSDSEKK-EDEEGKVGPGNHGTEGSGGERHSDT 343
E +G ++ E+ E + +++ E D E + E+EEG+ EG G E
Sbjct: 914 EEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGE 973
Query: 344 DSDRREDDRSQHSSGNGNDFEMITKEELEQQTDGDCEEDEEEENDGE 390
+ + + G G + E + E E + + + E + EEE +GE
Sbjct: 974 GEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGE 1020
Score = 36.6 bits (83), Expect = 0.041
Identities = 20/77 (25%), Positives = 47/77 (61%), Gaps = 2/77 (2%)
Query: 107 KKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGTPKKKETKK 166
+++++ G+ E G+ E+ K ++E ++E+ + +E++ +GE+EE + EE G K +E +
Sbjct: 806 EEKEEGGEVEGGEVEEGKGERE--EEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGE 863
Query: 167 KFKLEPHDDQVFLDGNE 183
+ + E ++ +G E
Sbjct: 864 EGEGEEEGEEGEGEGEE 880
Score = 36.2 bits (82), Expect = 0.054
Identities = 21/79 (26%), Positives = 43/79 (54%), Gaps = 20/79 (25%)
Query: 109 EKDKGKAESGKEEDKKSKKENIKDEKTK-------------------KEKEKKKDGE-KE 148
EK++ K G+E+++K +++ + E+ + +E+E++K+GE KE
Sbjct: 698 EKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKE 757
Query: 149 ESKKEETPGTPKKKETKKK 167
E + EE G +K+E ++K
Sbjct: 758 EGEGEEVEGEREKEEGERK 776
Score = 36.2 bits (82), Expect = 0.054
Identities = 23/80 (28%), Positives = 48/80 (60%), Gaps = 8/80 (10%)
Query: 108 KEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKD---GEKEESKKEETPGTPKKKET 164
+E+++ K GKEE + E ++ E+ K+E E+KK+ G++E+ ++E G +++ET
Sbjct: 745 REEEEEKEGEGKEE---GEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEET 801
Query: 165 KKKFKLEPHDDQVFLDGNEV 184
+ + + + +V +G EV
Sbjct: 802 EGRGEEKEEGGEV--EGGEV 819
Score = 35.8 bits (81), Expect = 0.070
Identities = 27/114 (23%), Positives = 49/114 (42%), Gaps = 17/114 (14%)
Query: 301 TKKQQKSDSEEKSDSEKKEDEEGKVGPGNHGTEGSGGERHSDTDSDRREDDRSQHSSGNG 360
T ++ S +E D E+++ E+ K G G G G + ++ + ++ D Q
Sbjct: 658 TCEEGSSGAEHWQDEEREKGEKDK-GRGEMERPGEGEKELAEKEEWKKRDGEEQEQKERE 716
Query: 361 NDFEMITKEELEQ----------QTDGDCEEDEE------EENDGETPKSSHEK 398
+ +E+E+ + +GD EE+EE EE +GE + EK
Sbjct: 717 QGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREK 770
Score = 35.4 bits (80), Expect = 0.092
Identities = 18/68 (26%), Positives = 40/68 (58%), Gaps = 2/68 (2%)
Query: 108 KEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGTPKKKETKKK 167
+E++KG+ + G+ E ++ + + E +KE+ KK+DGE++E K+ E ++ + ++
Sbjct: 672 EEREKGEKDKGRGEMERPGEG--EKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEE 729
Query: 168 FKLEPHDD 175
E H +
Sbjct: 730 GGEEEHGE 737
Score = 35.4 bits (80), Expect = 0.092
Identities = 27/104 (25%), Positives = 48/104 (46%), Gaps = 21/104 (20%)
Query: 101 KYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEK------------------- 141
K + + KKE+ GK E G+EE + + E + E +EKE+
Sbjct: 770 KEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEE 829
Query: 142 --KKDGEKEESKKEETPGTPKKKETKKKFKLEPHDDQVFLDGNE 183
+ +GE+EE + EE G +++E + K + E + + +G E
Sbjct: 830 EEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEE 873
Score = 34.3 bits (77), Expect = 0.20
Identities = 14/61 (22%), Positives = 37/61 (60%)
Query: 109 EKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGTPKKKETKKKF 168
E ++G+ E +EE ++ +E K+ + ++ + +++ E+EE K +ET +++ +++
Sbjct: 1026 EGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEY 1085
Query: 169 K 169
K
Sbjct: 1086 K 1086
Score = 33.1 bits (74), Expect = 0.45
Identities = 19/60 (31%), Positives = 38/60 (63%), Gaps = 4/60 (6%)
Query: 112 KGKAESGKEEDKKSKKENIKDE-KTKKEKEKKKDGEKEESKKEET---PGTPKKKETKKK 167
+G+ E G+EE ++ +KE +E + +E+E++++G+ +E+ +EE G KK +K K
Sbjct: 1033 EGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYKKVSKIK 1092
Score = 32.7 bits (73), Expect = 0.59
Identities = 20/66 (30%), Positives = 40/66 (60%), Gaps = 5/66 (7%)
Query: 107 KKEKDKGKAES---GKEEDKKSKKENIK--DEKTKKEKEKKKDGEKEESKKEETPGTPKK 161
K EKDKG+ E G+ E + ++KE K D + +++KE+++ +KE +++ E G +
Sbjct: 676 KGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEH 735
Query: 162 KETKKK 167
E +++
Sbjct: 736 GEGEEE 741
Score = 32.7 bits (73), Expect = 0.59
Identities = 19/72 (26%), Positives = 43/72 (59%), Gaps = 4/72 (5%)
Query: 96 KVMKMKYDKDIKKEKDKGKAESGKEEDKKSKKENI----KDEKTKKEKEKKKDGEKEESK 151
+V + K +++ ++E+ +G+ E G+ E+++ + E K E+ +E E +++GE+ E +
Sbjct: 818 EVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGE 877
Query: 152 KEETPGTPKKKE 163
EE G + +E
Sbjct: 878 GEEEEGEGEGEE 889
Score = 32.3 bits (72), Expect = 0.78
Identities = 16/60 (26%), Positives = 36/60 (60%), Gaps = 2/60 (3%)
Query: 109 EKDKGKAESGKEEDKKSKKENIKDEKTKKEK--EKKKDGEKEESKKEETPGTPKKKETKK 166
EK+ + E K+ D + +++ +++ +KE+ E ++ GE+E + EE G +++E K+
Sbjct: 693 EKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKE 752
Score = 31.2 bits (69), Expect = 1.7
Identities = 23/75 (30%), Positives = 38/75 (50%), Gaps = 15/75 (20%)
Query: 108 KEKDKGKAESGKE-------EDKKSKKENIKDEKTKK--------EKEKKKDGEKEESKK 152
K K G+AE G E E+ S E+ +DE+ +K E E+ +GEKE ++K
Sbjct: 640 KAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEK 699
Query: 153 EETPGTPKKKETKKK 167
EE +++ +K+
Sbjct: 700 EEWKKRDGEEQEQKE 714
Score = 31.2 bits (69), Expect = 1.7
Identities = 18/60 (30%), Positives = 39/60 (65%), Gaps = 4/60 (6%)
Query: 108 KEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESK---KEETPGTPKKKET 164
+E+++G+ E G+ E ++ + E ++E ++ +E++K+GE EE++ +EE K +ET
Sbjct: 1014 EEEEEGEVE-GEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQET 1072
Score = 30.0 bits (66), Expect = 3.8
Identities = 21/78 (26%), Positives = 45/78 (57%), Gaps = 2/78 (2%)
Query: 108 KEKDKGKAESGKEEDKKSKKENIKDE-KTKKEKEKKKDGEKEESKKE-ETPGTPKKKETK 165
K +++G+ G+EE ++ + E ++E + + E+E + +GE+EE + E E G + +E +
Sbjct: 857 KGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEE 916
Query: 166 KKFKLEPHDDQVFLDGNE 183
+ K E ++ +G E
Sbjct: 917 GEGKGEEEGEEGEGEGEE 934
Score = 30.0 bits (66), Expect = 3.8
Identities = 14/46 (30%), Positives = 29/46 (63%)
Query: 109 EKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEE 154
E ++G+ E +EE + +E +E+ ++E E +++GE E ++EE
Sbjct: 973 EGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEE 1018
Score = 29.6 bits (65), Expect = 5.0
Identities = 17/79 (21%), Positives = 42/79 (53%), Gaps = 3/79 (3%)
Query: 108 KEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESK---KEETPGTPKKKET 164
+E+ +G+ E +E + + + E + E +E+E +++GE+ E + +E +++E
Sbjct: 1006 EEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEE 1065
Query: 165 KKKFKLEPHDDQVFLDGNE 183
+ K++ ++ DG E
Sbjct: 1066 EGKYQETGEEENERQDGEE 1084
Score = 29.3 bits (64), Expect = 6.6
Identities = 14/68 (20%), Positives = 40/68 (58%)
Query: 109 EKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGTPKKKETKKKF 168
E+++G+ E +E + + ++E + + ++ +E + +GE+EE + E G + +E + ++
Sbjct: 896 EEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEW 955
Query: 169 KLEPHDDQ 176
+ E + +
Sbjct: 956 EGEEEEGE 963
Score = 29.3 bits (64), Expect = 6.6
Identities = 16/60 (26%), Positives = 36/60 (60%), Gaps = 3/60 (5%)
Query: 107 KKEKDKGKAES---GKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGTPKKKE 163
++E+ +G+ E G+ E+ + + E + E +E+E +++GE+E +EE G +++E
Sbjct: 958 EEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEE 1017
Score = 28.9 bits (63), Expect = 8.6
Identities = 17/61 (27%), Positives = 34/61 (55%), Gaps = 5/61 (8%)
Query: 112 KGKAESGKEE-----DKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGTPKKKETKK 166
+G+ E G+EE + + + E +E+ + E E + +GE+ E + EE G + +E +K
Sbjct: 989 EGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREK 1048
Query: 167 K 167
+
Sbjct: 1049 E 1049
>gi|239752449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 170
Score = 48.9 bits (115), Expect = 8e-06
Identities = 23/61 (37%), Positives = 40/61 (65%)
Query: 104 KDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGTPKKKE 163
++ KKEK+K K + K++ KK KK+ K +K KK+K+KK+ +++ +K + KKK+
Sbjct: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKK 161
Query: 164 T 164
T
Sbjct: 162 T 162
Score = 47.0 bits (110), Expect = 3e-05
Identities = 24/56 (42%), Positives = 36/56 (64%)
Query: 114 KAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGTPKKKETKKKFK 169
K E KE+ KK KK+ K +K KK+K+KKK +K++ K++ +KK+ KKK K
Sbjct: 105 KKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160
Score = 45.8 bits (107), Expect = 7e-05
Identities = 22/62 (35%), Positives = 39/62 (62%)
Query: 106 IKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGTPKKKETK 165
+ + ++K + E K++ KK KK+ K +K KK+K+KKK +K + K++ KK++ K
Sbjct: 99 LPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKK 158
Query: 166 KK 167
KK
Sbjct: 159 KK 160
Score = 45.4 bits (106), Expect = 9e-05
Identities = 22/54 (40%), Positives = 36/54 (66%)
Query: 116 ESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGTPKKKETKKKFK 169
E KE++K+ KK+ K +K KK+K+KKK +K++ KK+ +K++ KKK K
Sbjct: 103 EEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRK 156
Score = 44.7 bits (104), Expect = 2e-04
Identities = 21/64 (32%), Positives = 40/64 (62%)
Query: 99 KMKYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGT 158
K + +K+ KK+K K K + K++ KK KK+ K +K K+++++K+ +K+ KK++ G
Sbjct: 105 KKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTGN 164
Query: 159 PKKK 162
K
Sbjct: 165 EGAK 168
Score = 44.3 bits (103), Expect = 2e-04
Identities = 26/76 (34%), Positives = 42/76 (55%), Gaps = 7/76 (9%)
Query: 92 HRALKVMKMKYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESK 151
H L + + +K K+++ K K + K++ KK KK+ K +K KK+K K+K K + K
Sbjct: 93 HLPLHGLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRK 152
Query: 152 KEETPGTPKKKETKKK 167
K K+K+ KKK
Sbjct: 153 K-------KRKKKKKK 161
Score = 42.4 bits (98), Expect = 7e-04
Identities = 21/65 (32%), Positives = 39/65 (60%)
Query: 119 KEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGTPKKKETKKKFKLEPHDDQVF 178
+ E+KK K++ K +K KK+K+KKK +K++ KK++ K+K +K+ + + +
Sbjct: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKK 160
Query: 179 LDGNE 183
GNE
Sbjct: 161 KTGNE 165
Score = 42.4 bits (98), Expect = 7e-04
Identities = 24/65 (36%), Positives = 35/65 (53%)
Query: 93 RALKVMKMKYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKK 152
R K K K K KK+K K K + K++ KK KK+ K ++ +K K K+K K++ KK
Sbjct: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKK 161
Query: 153 EETPG 157
G
Sbjct: 162 TGNEG 166
Score = 38.9 bits (89), Expect = 0.008
Identities = 21/61 (34%), Positives = 34/61 (55%)
Query: 87 KKQFFHRALKVMKMKYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGE 146
KK+ K K K K KK+K K K + K++ +K K++ + K K++K+KKK G
Sbjct: 105 KKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTGN 164
Query: 147 K 147
+
Sbjct: 165 E 165
Score = 38.1 bits (87), Expect = 0.014
Identities = 21/57 (36%), Positives = 31/57 (54%)
Query: 96 KVMKMKYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKK 152
K K K K KK+K K K + K++ KK K++ + K KK+++KKK E K
Sbjct: 112 KKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTGNEGAK 168
Score = 35.4 bits (80), Expect = 0.092
Identities = 17/40 (42%), Positives = 26/40 (65%)
Query: 130 IKDEKTKKEKEKKKDGEKEESKKEETPGTPKKKETKKKFK 169
+ + KKEKEK+K +K++ KK++ KKK+ KKK K
Sbjct: 99 LPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKK 138
Score = 30.4 bits (67), Expect = 2.9
Identities = 14/53 (26%), Positives = 31/53 (58%)
Query: 272 VGFIDSFRPLYTHEYKGPKADLKKDEKSETKKQQKSDSEEKSDSEKKEDEEGK 324
+ F D+ L+ + P+ + KK+++ E KK++K ++K +KK+ ++ K
Sbjct: 83 IAFCDAGPSLHLPLHGLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKK 135
Score = 30.4 bits (67), Expect = 2.9
Identities = 19/55 (34%), Positives = 26/55 (47%)
Query: 87 KKQFFHRALKVMKMKYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEK 141
KK+ + K K K K KK+K K + K + K+ KK K +KT E K
Sbjct: 114 KKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTGNEGAK 168
>gi|19923236 nuclear antigen Sp100 isoform 2 [Homo sapiens]
Length = 879
Score = 48.9 bits (115), Expect = 8e-06
Identities = 26/67 (38%), Positives = 40/67 (59%), Gaps = 7/67 (10%)
Query: 88 KQFFHRALKVMKMKYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEK 147
KQF+ + +K KY KDI + KGK S +KK +K EK+KK+KE+++D E
Sbjct: 815 KQFYEKKAAKLKEKYKKDIAAYRAKGKPNS-------AKKRVVKAEKSKKKKEEEEDEED 867
Query: 148 EESKKEE 154
E+ ++ E
Sbjct: 868 EQEEENE 874
Score = 31.6 bits (70), Expect = 1.3
Identities = 12/33 (36%), Positives = 23/33 (69%)
Query: 290 KADLKKDEKSETKKQQKSDSEEKSDSEKKEDEE 322
K + K EKS+ KK+++ D E++ + E +ED++
Sbjct: 846 KKRVVKAEKSKKKKEEEEDEEDEQEEENEEDDD 878
Score = 29.3 bits (64), Expect = 6.6
Identities = 11/34 (32%), Positives = 23/34 (67%)
Query: 289 PKADLKKDEKSETKKQQKSDSEEKSDSEKKEDEE 322
P + K+ K+E K++K + E++ D +++E+EE
Sbjct: 842 PNSAKKRVVKAEKSKKKKEEEEDEEDEQEEENEE 875
>gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 family,
member E isoform 1 [Homo sapiens]
Length = 268
Score = 48.5 bits (114), Expect = 1e-05
Identities = 29/100 (29%), Positives = 45/100 (45%), Gaps = 6/100 (6%)
Query: 296 DEKSETKKQQKSDSEEKSDSEKKEDEEGKVGPGNHGTEGSGGERHSDTDSDRREDDRSQH 355
D++ + + +E D + +E+EE + GP E E D D D ED+
Sbjct: 149 DQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGS- 207
Query: 356 SSGNGND---FEMITKEELEQQTDGD--CEEDEEEENDGE 390
G G + + KEE++ + D D EE EEEE + E
Sbjct: 208 ELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEE 247
Score = 32.3 bits (72), Expect = 0.78
Identities = 15/65 (23%), Positives = 32/65 (49%), Gaps = 3/65 (4%)
Query: 333 EGSGGERHSDTDSDRREDDRSQHSSGNGNDFEMITKEELEQQTDGDCEEDEEEENDGETP 392
E E D D D +++ ++ +G +E +EE E++ + + E+++E+E E
Sbjct: 154 EAPDSEEEDDEDGDEDDEEEEENEAGPPEGYE---EEEEEEEEEDEDEDEDEDEAGSELG 210
Query: 393 KSSHE 397
+ E
Sbjct: 211 EGEEE 215
Score = 30.0 bits (66), Expect = 3.8
Identities = 24/109 (22%), Positives = 49/109 (44%), Gaps = 14/109 (12%)
Query: 288 GPKADLKKDEKSETKKQQKSDSEEKSDSEKKEDEEGKVGPGNHGTEGSGGERHSDTDSDR 347
G + D +++E + + EE+ + E ++++E + G+ EG S +
Sbjct: 166 GDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEE 225
Query: 348 REDDRSQHSSGNGNDFEMITKEELEQQTDG--------DCEEDEEEEND 388
+D+ + +D+ +EE E++ G D E+D EEE+D
Sbjct: 226 IQDEE------DDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD 268
Score = 28.9 bits (63), Expect = 8.6
Identities = 12/29 (41%), Positives = 18/29 (62%)
Query: 370 ELEQQTDGDCEEDEEEENDGETPKSSHEK 398
E E DGD +++EEEEN+ P+ E+
Sbjct: 159 EEEDDEDGDEDDEEEEENEAGPPEGYEEE 187
>gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32
family, member E isoform 2 [Homo sapiens]
Length = 227
Score = 48.5 bits (114), Expect = 1e-05
Identities = 29/100 (29%), Positives = 45/100 (45%), Gaps = 6/100 (6%)
Query: 296 DEKSETKKQQKSDSEEKSDSEKKEDEEGKVGPGNHGTEGSGGERHSDTDSDRREDDRSQH 355
D++ + + +E D + +E+EE + GP E E D D D ED+
Sbjct: 108 DQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGS- 166
Query: 356 SSGNGND---FEMITKEELEQQTDGD--CEEDEEEENDGE 390
G G + + KEE++ + D D EE EEEE + E
Sbjct: 167 ELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEE 206
Score = 32.3 bits (72), Expect = 0.78
Identities = 15/65 (23%), Positives = 32/65 (49%), Gaps = 3/65 (4%)
Query: 333 EGSGGERHSDTDSDRREDDRSQHSSGNGNDFEMITKEELEQQTDGDCEEDEEEENDGETP 392
E E D D D +++ ++ +G +E +EE E++ + + E+++E+E E
Sbjct: 113 EAPDSEEEDDEDGDEDDEEEEENEAGPPEGYE---EEEEEEEEEDEDEDEDEDEAGSELG 169
Query: 393 KSSHE 397
+ E
Sbjct: 170 EGEEE 174
Score = 30.0 bits (66), Expect = 3.8
Identities = 24/109 (22%), Positives = 49/109 (44%), Gaps = 14/109 (12%)
Query: 288 GPKADLKKDEKSETKKQQKSDSEEKSDSEKKEDEEGKVGPGNHGTEGSGGERHSDTDSDR 347
G + D +++E + + EE+ + E ++++E + G+ EG S +
Sbjct: 125 GDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEE 184
Query: 348 REDDRSQHSSGNGNDFEMITKEELEQQTDG--------DCEEDEEEEND 388
+D+ + +D+ +EE E++ G D E+D EEE+D
Sbjct: 185 IQDEE------DDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD 227
Score = 28.9 bits (63), Expect = 8.6
Identities = 12/29 (41%), Positives = 18/29 (62%)
Query: 370 ELEQQTDGDCEEDEEEENDGETPKSSHEK 398
E E DGD +++EEEEN+ P+ E+
Sbjct: 118 EEEDDEDGDEDDEEEEENEAGPPEGYEEE 146
>gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32
family, member E isoform 3 [Homo sapiens]
Length = 220
Score = 48.5 bits (114), Expect = 1e-05
Identities = 29/100 (29%), Positives = 45/100 (45%), Gaps = 6/100 (6%)
Query: 296 DEKSETKKQQKSDSEEKSDSEKKEDEEGKVGPGNHGTEGSGGERHSDTDSDRREDDRSQH 355
D++ + + +E D + +E+EE + GP E E D D D ED+
Sbjct: 101 DQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGS- 159
Query: 356 SSGNGND---FEMITKEELEQQTDGD--CEEDEEEENDGE 390
G G + + KEE++ + D D EE EEEE + E
Sbjct: 160 ELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEE 199
Score = 32.3 bits (72), Expect = 0.78
Identities = 15/65 (23%), Positives = 32/65 (49%), Gaps = 3/65 (4%)
Query: 333 EGSGGERHSDTDSDRREDDRSQHSSGNGNDFEMITKEELEQQTDGDCEEDEEEENDGETP 392
E E D D D +++ ++ +G +E +EE E++ + + E+++E+E E
Sbjct: 106 EAPDSEEEDDEDGDEDDEEEEENEAGPPEGYE---EEEEEEEEEDEDEDEDEDEAGSELG 162
Query: 393 KSSHE 397
+ E
Sbjct: 163 EGEEE 167
Score = 30.0 bits (66), Expect = 3.8
Identities = 24/109 (22%), Positives = 49/109 (44%), Gaps = 14/109 (12%)
Query: 288 GPKADLKKDEKSETKKQQKSDSEEKSDSEKKEDEEGKVGPGNHGTEGSGGERHSDTDSDR 347
G + D +++E + + EE+ + E ++++E + G+ EG S +
Sbjct: 118 GDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEE 177
Query: 348 REDDRSQHSSGNGNDFEMITKEELEQQTDG--------DCEEDEEEEND 388
+D+ + +D+ +EE E++ G D E+D EEE+D
Sbjct: 178 IQDEE------DDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD 220
Score = 28.9 bits (63), Expect = 8.6
Identities = 12/29 (41%), Positives = 18/29 (62%)
Query: 370 ELEQQTDGDCEEDEEEENDGETPKSSHEK 398
E E DGD +++EEEEN+ P+ E+
Sbjct: 111 EEEDDEDGDEDDEEEEENEAGPPEGYEEE 139
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 48.5 bits (114), Expect = 1e-05
Identities = 25/96 (26%), Positives = 56/96 (58%), Gaps = 3/96 (3%)
Query: 74 TRESVVDYCNRLLKKQFFHRALKVMKMKYDKDIKKEKDKGKAESGKEEDKKSKKENIKDE 133
+R+ D ++ +K+ + + + +K+ +KEK++GK K+ DK+ +K+ KD+
Sbjct: 373 SRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGK---NKDRDKEREKDREKDK 429
Query: 134 KTKKEKEKKKDGEKEESKKEETPGTPKKKETKKKFK 169
+ +E+E++K+ EK+ K++E +K+ K + K
Sbjct: 430 EKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSK 465
Score = 46.6 bits (109), Expect = 4e-05
Identities = 24/64 (37%), Positives = 39/64 (60%), Gaps = 3/64 (4%)
Query: 103 DKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGTPKKK 162
D+D ++EKD+ E KE+D++ ++E ++ KEKEK++D EKE K K+K
Sbjct: 416 DRDKEREKDR---EKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRK 472
Query: 163 ETKK 166
+ KK
Sbjct: 473 KDKK 476
Score = 45.8 bits (107), Expect = 7e-05
Identities = 27/113 (23%), Positives = 53/113 (46%), Gaps = 5/113 (4%)
Query: 292 DLKKDEKSETKKQQK---SDSEEKSDSEKKEDEEGKVGPGNHGTEGSGGERHSDTDSDRR 348
D +KD + + K++++ D E++ + EK+ ++E + G + +R D + DR
Sbjct: 375 DKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRE 434
Query: 349 EDDRSQHSSGNGNDFEMITKEELEQQTDGDCEEDEEEEND--GETPKSSHEKS 399
+ +H + E +E E++ D E DE+ + D TP S+ S
Sbjct: 435 REREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNAS 487
Score = 45.8 bits (107), Expect = 7e-05
Identities = 26/94 (27%), Positives = 51/94 (54%), Gaps = 1/94 (1%)
Query: 87 KKQFFHRALKVMKMKYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGE 146
K++ +K + +KD +KE+++ K E KE+++ K+ K+ + +EK+K+KD E
Sbjct: 376 KRKDTREKIKEKERVKEKDREKEREREK-EREKEKERGKNKDRDKEREKDREKDKEKDRE 434
Query: 147 KEESKKEETPGTPKKKETKKKFKLEPHDDQVFLD 180
+E K+ E +K++ + K K D +D
Sbjct: 435 REREKEHEKDRDKEKEKEQDKEKEREKDRSKEID 468
Score = 42.7 bits (99), Expect = 6e-04
Identities = 25/94 (26%), Positives = 48/94 (51%), Gaps = 2/94 (2%)
Query: 83 NRLLKKQFFHRALKVMKMKYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKK 142
NR +Q R K K K +E+ K ++ S + +K +E IK+++ KEK+++
Sbjct: 339 NRSRSRQKDRRRSKSPHKKRSKS--RERRKSRSRSHSRDKRKDTREKIKEKERVKEKDRE 396
Query: 143 KDGEKEESKKEETPGTPKKKETKKKFKLEPHDDQ 176
K+ E+E+ +++E K K++ K D +
Sbjct: 397 KEREREKEREKEKERGKNKDRDKEREKDREKDKE 430
Score = 41.2 bits (95), Expect = 0.002
Identities = 19/57 (33%), Positives = 37/57 (64%), Gaps = 3/57 (5%)
Query: 103 DKDIKKEKDKGKA---ESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETP 156
D++ KEKD+ + E K+ DK+ +KE K+++ +K++ K+ D ++++ KK TP
Sbjct: 424 DREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTP 480
Score = 35.0 bits (79), Expect = 0.12
Identities = 22/83 (26%), Positives = 44/83 (53%), Gaps = 5/83 (6%)
Query: 96 KVMKMKYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKE--KKKDGEKEESKKE 153
K + +D +K+ + E + ++K +KE ++++ +KEKE K KD +KE K
Sbjct: 366 KSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDR 425
Query: 154 ETPGTPKKKETKKKFKLEPHDDQ 176
E K+K+ +++ + E D+
Sbjct: 426 E---KDKEKDREREREKEHEKDR 445
Score = 35.0 bits (79), Expect = 0.12
Identities = 23/113 (20%), Positives = 44/113 (38%), Gaps = 2/113 (1%)
Query: 286 YKGPKADLKKDEKSETKKQQKSDSEEKSDSEKKEDEEGKVGPGNHGTEGSGGERHSDTDS 345
Y + + ++ + S ++ K P + + E+ D S
Sbjct: 484 YNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHIS 543
Query: 346 DRREDDRSQHSSGNGNDFEMITKEELEQQTDGDCEEDEEEENDGETPKSSHEK 398
+RRE +RS + ND + KE+LE+ + E++ +E D K +K
Sbjct: 544 ERRERERSTSMRKSSNDRD--GKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDK 594
Score = 34.7 bits (78), Expect = 0.16
Identities = 17/79 (21%), Positives = 37/79 (46%)
Query: 104 KDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGTPKKKE 163
KD K+EK++ +E ++ + +++ KEK +K +E + + P + KE
Sbjct: 531 KDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKE 590
Query: 164 TKKKFKLEPHDDQVFLDGN 182
K ++++ +GN
Sbjct: 591 VDDKDAPRTEENKIQHNGN 609
Score = 33.5 bits (75), Expect = 0.35
Identities = 27/97 (27%), Positives = 46/97 (47%), Gaps = 12/97 (12%)
Query: 287 KGPKADLKKDEKSETKKQQKSDSEEKSDS-----EKKEDEEGKVGPGNHGTE--GSGGER 339
K K + ++D SE +++++S S KS + EK E + H E S +
Sbjct: 531 KDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKE 590
Query: 340 HSDTDSDRREDDRSQHSSGNGNDFEMITKEELEQQTD 376
D D+ R E+++ QH NGN + +E L +T+
Sbjct: 591 VDDKDAPRTEENKIQH---NGNC--QLNEENLSTKTE 622
Score = 32.3 bits (72), Expect = 0.78
Identities = 15/67 (22%), Positives = 35/67 (52%), Gaps = 3/67 (4%)
Query: 101 KYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGTPK 160
+++KD KEK+K E KE++++ + DEK KK+K+ + + + + +
Sbjct: 440 EHEKDRDKEKEK---EQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRE 496
Query: 161 KKETKKK 167
++ + +
Sbjct: 497 RRRRRSR 503
Score = 32.0 bits (71), Expect = 1.0
Identities = 18/75 (24%), Positives = 38/75 (50%), Gaps = 5/75 (6%)
Query: 96 KVMKMKYDKDIKKEKDKGK-AESGKEEDKKS----KKENIKDEKTKKEKEKKKDGEKEES 150
K + + DK+ ++EKD+ K + +++DKKS + N +E+++ + S
Sbjct: 447 KEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSS 506
Query: 151 KKEETPGTPKKKETK 165
+ T T K+K ++
Sbjct: 507 RSPRTSKTIKRKSSR 521
Score = 31.6 bits (70), Expect = 1.3
Identities = 22/115 (19%), Positives = 51/115 (44%), Gaps = 4/115 (3%)
Query: 287 KGPKADLKKDEKSE--TKKQQKSDSEEKSDSEKKEDEEGKVGPGNHGTEGSGGERHSDTD 344
K + D K+++ E +K+++ D ++ D ++K+D++ + P ++ S R S +
Sbjct: 439 KEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSY--NASRRSRSSSRE 496
Query: 345 SDRREDDRSQHSSGNGNDFEMITKEELEQQTDGDCEEDEEEENDGETPKSSHEKS 399
RR S S + + ++ ++ E+E D + + E+S
Sbjct: 497 RRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERS 551
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 48.5 bits (114), Expect = 1e-05
Identities = 25/96 (26%), Positives = 56/96 (58%), Gaps = 3/96 (3%)
Query: 74 TRESVVDYCNRLLKKQFFHRALKVMKMKYDKDIKKEKDKGKAESGKEEDKKSKKENIKDE 133
+R+ D ++ +K+ + + + +K+ +KEK++GK K+ DK+ +K+ KD+
Sbjct: 257 SRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGK---NKDRDKEREKDREKDK 313
Query: 134 KTKKEKEKKKDGEKEESKKEETPGTPKKKETKKKFK 169
+ +E+E++K+ EK+ K++E +K+ K + K
Sbjct: 314 EKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSK 349
Score = 46.6 bits (109), Expect = 4e-05
Identities = 24/64 (37%), Positives = 39/64 (60%), Gaps = 3/64 (4%)
Query: 103 DKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGTPKKK 162
D+D ++EKD+ E KE+D++ ++E ++ KEKEK++D EKE K K+K
Sbjct: 300 DRDKEREKDR---EKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRK 356
Query: 163 ETKK 166
+ KK
Sbjct: 357 KDKK 360
Score = 45.8 bits (107), Expect = 7e-05
Identities = 27/113 (23%), Positives = 53/113 (46%), Gaps = 5/113 (4%)
Query: 292 DLKKDEKSETKKQQK---SDSEEKSDSEKKEDEEGKVGPGNHGTEGSGGERHSDTDSDRR 348
D +KD + + K++++ D E++ + EK+ ++E + G + +R D + DR
Sbjct: 259 DKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRE 318
Query: 349 EDDRSQHSSGNGNDFEMITKEELEQQTDGDCEEDEEEEND--GETPKSSHEKS 399
+ +H + E +E E++ D E DE+ + D TP S+ S
Sbjct: 319 REREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNAS 371
Score = 45.8 bits (107), Expect = 7e-05
Identities = 26/94 (27%), Positives = 51/94 (54%), Gaps = 1/94 (1%)
Query: 87 KKQFFHRALKVMKMKYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGE 146
K++ +K + +KD +KE+++ K E KE+++ K+ K+ + +EK+K+KD E
Sbjct: 260 KRKDTREKIKEKERVKEKDREKEREREK-EREKEKERGKNKDRDKEREKDREKDKEKDRE 318
Query: 147 KEESKKEETPGTPKKKETKKKFKLEPHDDQVFLD 180
+E K+ E +K++ + K K D +D
Sbjct: 319 REREKEHEKDRDKEKEKEQDKEKEREKDRSKEID 352
Score = 42.7 bits (99), Expect = 6e-04
Identities = 25/94 (26%), Positives = 48/94 (51%), Gaps = 2/94 (2%)
Query: 83 NRLLKKQFFHRALKVMKMKYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKK 142
NR +Q R K K K +E+ K ++ S + +K +E IK+++ KEK+++
Sbjct: 223 NRSRSRQKDRRRSKSPHKKRSKS--RERRKSRSRSHSRDKRKDTREKIKEKERVKEKDRE 280
Query: 143 KDGEKEESKKEETPGTPKKKETKKKFKLEPHDDQ 176
K+ E+E+ +++E K K++ K D +
Sbjct: 281 KEREREKEREKEKERGKNKDRDKEREKDREKDKE 314
Score = 41.2 bits (95), Expect = 0.002
Identities = 19/57 (33%), Positives = 37/57 (64%), Gaps = 3/57 (5%)
Query: 103 DKDIKKEKDKGKA---ESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETP 156
D++ KEKD+ + E K+ DK+ +KE K+++ +K++ K+ D ++++ KK TP
Sbjct: 308 DREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTP 364
Score = 35.0 bits (79), Expect = 0.12
Identities = 22/83 (26%), Positives = 44/83 (53%), Gaps = 5/83 (6%)
Query: 96 KVMKMKYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKE--KKKDGEKEESKKE 153
K + +D +K+ + E + ++K +KE ++++ +KEKE K KD +KE K
Sbjct: 250 KSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDR 309
Query: 154 ETPGTPKKKETKKKFKLEPHDDQ 176
E K+K+ +++ + E D+
Sbjct: 310 E---KDKEKDREREREKEHEKDR 329
Score = 35.0 bits (79), Expect = 0.12
Identities = 23/113 (20%), Positives = 44/113 (38%), Gaps = 2/113 (1%)
Query: 286 YKGPKADLKKDEKSETKKQQKSDSEEKSDSEKKEDEEGKVGPGNHGTEGSGGERHSDTDS 345
Y + + ++ + S ++ K P + + E+ D S
Sbjct: 368 YNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHIS 427
Query: 346 DRREDDRSQHSSGNGNDFEMITKEELEQQTDGDCEEDEEEENDGETPKSSHEK 398
+RRE +RS + ND + KE+LE+ + E++ +E D K +K
Sbjct: 428 ERRERERSTSMRKSSNDRD--GKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDK 478
Score = 34.7 bits (78), Expect = 0.16
Identities = 17/79 (21%), Positives = 37/79 (46%)
Query: 104 KDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGTPKKKE 163
KD K+EK++ +E ++ + +++ KEK +K +E + + P + KE
Sbjct: 415 KDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKE 474
Query: 164 TKKKFKLEPHDDQVFLDGN 182
K ++++ +GN
Sbjct: 475 VDDKDAPRTEENKIQHNGN 493
Score = 33.5 bits (75), Expect = 0.35
Identities = 27/97 (27%), Positives = 46/97 (47%), Gaps = 12/97 (12%)
Query: 287 KGPKADLKKDEKSETKKQQKSDSEEKSDS-----EKKEDEEGKVGPGNHGTE--GSGGER 339
K K + ++D SE +++++S S KS + EK E + H E S +
Sbjct: 415 KDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKE 474
Query: 340 HSDTDSDRREDDRSQHSSGNGNDFEMITKEELEQQTD 376
D D+ R E+++ QH NGN + +E L +T+
Sbjct: 475 VDDKDAPRTEENKIQH---NGNC--QLNEENLSTKTE 506
Score = 32.3 bits (72), Expect = 0.78
Identities = 15/67 (22%), Positives = 35/67 (52%), Gaps = 3/67 (4%)
Query: 101 KYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGTPK 160
+++KD KEK+K E KE++++ + DEK KK+K+ + + + + +
Sbjct: 324 EHEKDRDKEKEK---EQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRE 380
Query: 161 KKETKKK 167
++ + +
Sbjct: 381 RRRRRSR 387
Score = 32.0 bits (71), Expect = 1.0
Identities = 18/75 (24%), Positives = 38/75 (50%), Gaps = 5/75 (6%)
Query: 96 KVMKMKYDKDIKKEKDKGK-AESGKEEDKKS----KKENIKDEKTKKEKEKKKDGEKEES 150
K + + DK+ ++EKD+ K + +++DKKS + N +E+++ + S
Sbjct: 331 KEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSS 390
Query: 151 KKEETPGTPKKKETK 165
+ T T K+K ++
Sbjct: 391 RSPRTSKTIKRKSSR 405
Score = 31.6 bits (70), Expect = 1.3
Identities = 22/115 (19%), Positives = 51/115 (44%), Gaps = 4/115 (3%)
Query: 287 KGPKADLKKDEKSE--TKKQQKSDSEEKSDSEKKEDEEGKVGPGNHGTEGSGGERHSDTD 344
K + D K+++ E +K+++ D ++ D ++K+D++ + P ++ S R S +
Sbjct: 323 KEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSY--NASRRSRSSSRE 380
Query: 345 SDRREDDRSQHSSGNGNDFEMITKEELEQQTDGDCEEDEEEENDGETPKSSHEKS 399
RR S S + + ++ ++ E+E D + + E+S
Sbjct: 381 RRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERS 435
>gi|4504425 high-mobility group box 1 [Homo sapiens]
Length = 215
Score = 48.1 bits (113), Expect = 1e-05
Identities = 26/67 (38%), Positives = 42/67 (62%), Gaps = 7/67 (10%)
Query: 88 KQFFHRALKVMKMKYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEK 147
KQ + + +K KY+KDI + KGK ++ +KK +K EK+KK+KE+++D E
Sbjct: 141 KQPYEKKAAKLKEKYEKDIAAYRAKGKPDA-------AKKGVVKAEKSKKKKEEEEDEED 193
Query: 148 EESKKEE 154
EE ++EE
Sbjct: 194 EEDEEEE 200
Score = 36.2 bits (82), Expect = 0.054
Identities = 15/33 (45%), Positives = 24/33 (72%)
Query: 290 KADLKKDEKSETKKQQKSDSEEKSDSEKKEDEE 322
K + K EKS+ KK+++ D E++ D E++EDEE
Sbjct: 172 KKGVVKAEKSKKKKEEEEDEEDEEDEEEEEDEE 204
Score = 30.4 bits (67), Expect = 2.9
Identities = 12/33 (36%), Positives = 21/33 (63%)
Query: 290 KADLKKDEKSETKKQQKSDSEEKSDSEKKEDEE 322
KA+ K +K E + ++ + EE+ + E+ EDEE
Sbjct: 177 KAEKSKKKKEEEEDEEDEEDEEEEEDEEDEDEE 209
Score = 29.6 bits (65), Expect = 5.0
Identities = 18/63 (28%), Positives = 27/63 (42%), Gaps = 18/63 (28%)
Query: 289 PKADLKKDEKSETKKQQKSDSEEKSDSEKKEDEEGKVGPGNHGTEGSGGERHSDTDSDRR 348
P A K K+E K++K + E++ D E +E+EE + D D
Sbjct: 168 PDAAKKGVVKAEKSKKKKEEEEDEEDEEDEEEEE------------------DEEDEDEE 209
Query: 349 EDD 351
EDD
Sbjct: 210 EDD 212
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 47.4 bits (111), Expect = 2e-05
Identities = 24/77 (31%), Positives = 51/77 (66%), Gaps = 1/77 (1%)
Query: 109 EKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGTPKKKETKKKF 168
E +K ++ S +EE+++ ++E ++E+ ++E+E++K+ E+ E K+ E KKK+ K+K
Sbjct: 2236 ELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKK 2295
Query: 169 KLEPHD-DQVFLDGNEV 184
K E + ++VF + E+
Sbjct: 2296 KEEVQEKEEVFEEKEEI 2312
Score = 40.4 bits (93), Expect = 0.003
Identities = 19/75 (25%), Positives = 46/75 (61%)
Query: 103 DKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGTPKKK 162
+++ ++E+++ + E +EE+++ K+E +EK +++E++K +K+E KKEE +
Sbjct: 2247 EEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVF 2306
Query: 163 ETKKKFKLEPHDDQV 177
E K++ E + +
Sbjct: 2307 EEKEEIMSEEETESL 2321
Score = 40.0 bits (92), Expect = 0.004
Identities = 27/84 (32%), Positives = 47/84 (55%), Gaps = 13/84 (15%)
Query: 103 DKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKD--GEKEE--------SKK 152
++++++E+++ K E EE + K+E +EK KK+KEKKK+ EKEE +
Sbjct: 2259 EEEVREEEEERKEEEEGEEKQVEKEE---EEKKKKKKEKKKEEVQEKEEVFEEKEEIMSE 2315
Query: 153 EETPGTPKKKETKKKFKLEPHDDQ 176
EET ++E ++ LE D+
Sbjct: 2316 EETESLSDEEEEEESCSLEEEVDR 2339
Score = 39.7 bits (91), Expect = 0.005
Identities = 24/107 (22%), Positives = 51/107 (47%), Gaps = 4/107 (3%)
Query: 296 DEKSETKKQQKSDSEEKSDSEKKEDEEGKVGPGNHGTEGSGGERHSDTDSDRREDDRSQH 355
DE + + + EE+ + E++E+EE + E G E+ + + + ++ + +
Sbjct: 2235 DELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEK 2294
Query: 356 SSGNGNDFEMI--TKEEL--EQQTDGDCEEDEEEENDGETPKSSHEK 398
+ E + KEE+ E++T+ +E+EEEE+ + EK
Sbjct: 2295 KKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREK 2341
Score = 35.4 bits (80), Expect = 0.092
Identities = 20/76 (26%), Positives = 43/76 (56%)
Query: 96 KVMKMKYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEET 155
K ++ + ++ KK+K+K K E ++E+ +KE I E+ + +++ E+ S +EE
Sbjct: 2278 KQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEV 2337
Query: 156 PGTPKKKETKKKFKLE 171
+ + +K+FKL+
Sbjct: 2338 DREKEILKKEKQFKLQ 2353
Score = 33.9 bits (76), Expect = 0.27
Identities = 35/126 (27%), Positives = 64/126 (50%), Gaps = 20/126 (15%)
Query: 66 KGEEALFTTRESVVDYCNRLLKKQFFHRALKVMKMKYDKDIK--KEKDKGKAESGKEEDK 123
K +E L T + +V + L KKQ A + MK+ +K + K++ +G+ + KEE
Sbjct: 1904 KKKEKLAETEKKLVQVEDSLAKKQE-KLAQEKMKLALEKAMVQGKKRLRGELDIAKEE-- 1960
Query: 124 KSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGTPKKKET--------KKKFKLEP--- 172
K N++ ++ +EK + +G KE K ETP T ++++ ++K LE
Sbjct: 1961 --KALNLEMKRLAEEKMRLVEG-KETLSKGETPETSRQRKMTQVEQELFERKLSLEEKIL 2017
Query: 173 -HDDQV 177
H+D++
Sbjct: 2018 LHEDRI 2023
Score = 32.0 bits (71), Expect = 1.0
Identities = 33/148 (22%), Positives = 66/148 (44%), Gaps = 34/148 (22%)
Query: 57 LDSKWAKAKKGEEALFTTRESVVDYCNRLLKK-------------QFFHRALKVMKMKYD 103
L KW K + EE L + + N L +K Q A ++ ++++D
Sbjct: 1665 LAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWD 1724
Query: 104 -KDIKKEKDKGKAESGKEEDKKSK-----------KENIKDEKTK---------KEKEKK 142
+++ ++++ E GK ++K K +E + +E+TK +EKEK
Sbjct: 1725 MEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKL 1784
Query: 143 KDGEKEESKKEETPGTPKKKETKKKFKL 170
+++ ++EE G +++ +KK KL
Sbjct: 1785 AQHKEKMPEEEERLGRKREQLIEKKMKL 1812
Score = 30.4 bits (67), Expect = 2.9
Identities = 22/97 (22%), Positives = 48/97 (49%), Gaps = 3/97 (3%)
Query: 51 KAVDCL-LDSKWAKAKKGEEALFTTRESVVDYCNRLLKKQFFHRALKVMKMKYDKDIKKE 109
KA D L L+ KKG++ +F +V + + K+ + + + K ++KE
Sbjct: 1353 KARDMLGLEETQVILKKGKKVIFLEPGNVT--MGKEISKKEEKKTFQKSPKQGRKAVQKE 1410
Query: 110 KDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGE 146
+ GK + ++++ E +++ T +EK K++G+
Sbjct: 1411 RKVGKIKREMTKEERDMSEEVEEMATLEEKVVKQEGK 1447
Score = 30.4 bits (67), Expect = 2.9
Identities = 18/67 (26%), Positives = 39/67 (58%), Gaps = 3/67 (4%)
Query: 104 KDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGTPKKKE 163
K+I K+++K + ++ +K+ ++ K K K+E K+ E++ S++ E T ++K
Sbjct: 1385 KEISKKEEKKTFQKSPKQGRKAVQKERKVGKIKREMTKE---ERDMSEEVEEMATLEEKV 1441
Query: 164 TKKKFKL 170
K++ KL
Sbjct: 1442 VKQEGKL 1448
Score = 29.6 bits (65), Expect = 5.0
Identities = 23/74 (31%), Positives = 35/74 (47%), Gaps = 5/74 (6%)
Query: 97 VMKMKYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTK----KEKEKKKDGEKEESKK 152
V+K+ D D +EKD K + K + +D+K K+K KKK E + +
Sbjct: 1146 VIKLSKDVD-SQEKDISKDHIALTLKRLQKIRDKRDKKATAQKLKKKHKKKGKEAKVINE 1204
Query: 153 EETPGTPKKKETKK 166
E TP ++ TKK
Sbjct: 1205 ETTPPVMEQPVTKK 1218
Score = 29.6 bits (65), Expect = 5.0
Identities = 17/81 (20%), Positives = 38/81 (46%)
Query: 285 EYKGPKADLKKDEKSETKKQQKSDSEEKSDSEKKEDEEGKVGPGNHGTEGSGGERHSDTD 344
E +G + ++K+E+ + KK+++ EE + E+ +E+ ++ S E ++
Sbjct: 2272 EEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESC 2331
Query: 345 SDRREDDRSQHSSGNGNDFEM 365
S E DR + F++
Sbjct: 2332 SLEEEVDREKEILKKEKQFKL 2352
>gi|169202818 PREDICTED: similar to hCG1991922 [Homo sapiens]
Length = 488
Score = 47.4 bits (111), Expect = 2e-05
Identities = 26/97 (26%), Positives = 52/97 (53%), Gaps = 8/97 (8%)
Query: 88 KQFFHRALKVMKMKYDKDIKKEKDKGK--------AESGKEEDKKSKKENIKDEKTKKEK 139
KQ + + +K KY+KDI + KGK ++ K + KK ++EN +DE+ ++E+
Sbjct: 277 KQPYEKRSAKLKEKYEKDIAAYRAKGKHDAANNGVVKAAKSKKKKEEEENEEDEEDEEEE 336
Query: 140 EKKKDGEKEESKKEETPGTPKKKETKKKFKLEPHDDQ 176
+ ++D ++E+ + EE G ++ + P D +
Sbjct: 337 KDEEDEDEEDDEDEEEDGDDEQSHWQLFLACCPEDQR 373
Score = 33.5 bits (75), Expect = 0.35
Identities = 22/99 (22%), Positives = 40/99 (40%), Gaps = 14/99 (14%)
Query: 296 DEKSETKKQQKSDSEEKSDSEKKEDEEGKVGPGNHGTEGSGGERHSDTDSDRREDDRSQH 355
D+K +K+ E+ +GK N+G + + + + ED+ +
Sbjct: 275 DDKQPYEKRSAKLKEKYEKDIAAYRAKGKHDAANNGVVKAAKSKKKKEEEENEEDEEDE- 333
Query: 356 SSGNGNDFEMITKEELEQQTDGDCEEDEEEENDGETPKS 394
EE + + D D E+DE+EE DG+ +S
Sbjct: 334 -------------EEEKDEEDEDEEDDEDEEEDGDDEQS 359
Score = 32.3 bits (72), Expect = 0.78
Identities = 16/61 (26%), Positives = 29/61 (47%), Gaps = 13/61 (21%)
Query: 295 KDEKSETKKQQKSDSEEKSDSEKKEDEEGKVGPGNHGTEGSGGERHSDTDSDRREDDRSQ 354
K KS+ KK+++ + E++ D E+++DEE + + D D + DD
Sbjct: 313 KAAKSKKKKEEEENEEDEEDEEEEKDEEDE-------------DEEDDEDEEEDGDDEQS 359
Query: 355 H 355
H
Sbjct: 360 H 360
Score = 28.9 bits (63), Expect = 8.6
Identities = 17/45 (37%), Positives = 22/45 (48%)
Query: 125 SKKENIKDEKTKKEKEKKKDGEKEESKKEETPGTPKKKETKKKFK 169
S KE K + + + E +K K+E P K ETKKKFK
Sbjct: 182 SAKEKGKFGRARGKFEDMAKADKAHYKREMKTYIPPKGETKKKFK 226
>gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo
sapiens]
Length = 956
Score = 47.4 bits (111), Expect = 2e-05
Identities = 30/89 (33%), Positives = 54/89 (60%), Gaps = 5/89 (5%)
Query: 83 NRLLKKQFFHRALKVMKMKYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKK 142
N+L ++ R K +K++ +++ +KEK K +A+ KEE KK K+E EK KEKE++
Sbjct: 333 NKLRLQRDQERLGKQLKLRAERE-EKEKLKEEAKRAKEEAKKKKEE----EKELKEKERR 387
Query: 143 KDGEKEESKKEETPGTPKKKETKKKFKLE 171
+ EK+E +K E +++ +++ LE
Sbjct: 388 EKREKDEKEKAEKQRLKEERRKERQEALE 416
Score = 46.2 bits (108), Expect = 5e-05
Identities = 30/83 (36%), Positives = 48/83 (57%), Gaps = 3/83 (3%)
Query: 86 LKKQFFHRALKVMKMKYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEK-KKD 144
L KQ RA + K K ++ K+ K++ K + KEE+K+ K++ ++++ K EKEK +K
Sbjct: 344 LGKQLKLRAEREEKEKLKEEAKRAKEEAKKK--KEEEKELKEKERREKREKDEKEKAEKQ 401
Query: 145 GEKEESKKEETPGTPKKKETKKK 167
KEE +KE K E K+K
Sbjct: 402 RLKEERRKERQEALEAKLEEKRK 424
Score = 40.4 bits (93), Expect = 0.003
Identities = 22/73 (30%), Positives = 47/73 (64%), Gaps = 5/73 (6%)
Query: 99 KMKYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEKEKKKDGEKEESKKEETPGT 158
K + +K++K+++ + K E K+E +K++K+ +K+E+ K+ +E + +E+ KKEE
Sbjct: 374 KKEEEKELKEKERREKRE--KDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEE---E 428
Query: 159 PKKKETKKKFKLE 171
+ +E +K+ K E
Sbjct: 429 KRLREEEKRIKAE 441
Score = 39.3 bits (90), Expect = 0.006
Identities = 29/89 (32%), Positives = 49/89 (55%), Gaps = 12/89 (13%)
Query: 87 KKQFFHRALKVMKMKYDKDIKKEKDKGKAESGKEEDKKSKKENIK---DEKTKKEKEKKK 143
KK+ + LK K + +K K EK+K + + KEE +K ++E ++ +EK KKE+EK+
Sbjct: 373 KKKEEEKELKE-KERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRL 431
Query: 144 DGEKEESKKE--------ETPGTPKKKET 164
E++ K E + P TP+ +T
Sbjct: 432 REEEKRIKAEKAEITRFFQKPKTPQAPKT 460
Score = 33.5 bits (75), Expect = 0.35
Identities = 21/74 (28%), Positives = 40/74 (54%), Gaps = 9/74 (12%)
Query: 104 KDIKKEKDKGKAESGKEEDKKSKKENIKDEKTKKEK---EKKKDGEKEESKKEETPGTPK 160
K +K +K K +++++ K+ ++ E+ +KEK E K+ E+ + KKEE
Sbjct: 324 KFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEE------ 377
Query: 161 KKETKKKFKLEPHD 174
+KE K+K + E +
Sbjct: 378 EKELKEKERREKRE 391
>gi|194688135 high-mobility group box 2 [Homo sapiens]
Length = 209
Score = 47.0 bits (110), Expect = 3e-05
Identities = 24/69 (34%), Positives = 45/69 (65%), Gaps = 3/69 (4%)
Query: 88 KQFFHRALKVMKMKYDKDIKKEKDKGKAESGKEEDKK---SKKENIKDEKTKKEKEKKKD 144
KQ + + +K KY+KDI + KGK+E+GK+ + SKK+N +++ ++E+E+ +D
Sbjct: 141 KQPYEQKAAKLKEKYEKDIAAYRAKGKSEAGKKGPGRPTGSKKKNEPEDEEEEEEEEDED 200
Query: 145 GEKEESKKE 153
E+E+ +E
Sbjct: 201 EEEEDEDEE 209
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.131 0.378
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,178,301
Number of Sequences: 37866
Number of extensions: 923279
Number of successful extensions: 34851
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 751
Number of HSP's successfully gapped in prelim test: 613
Number of HSP's that attempted gapping in prelim test: 10390
Number of HSP's gapped (non-prelim): 14604
length of query: 399
length of database: 18,247,518
effective HSP length: 104
effective length of query: 295
effective length of database: 14,309,454
effective search space: 4221288930
effective search space used: 4221288930
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.