Guide to the Human Genome
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Search of human proteins with 4507297

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4507297 syntaxin binding protein 1 isoform a [Homo sapiens]
         (603 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4507297 syntaxin binding protein 1 isoform a [Homo sapiens]       1201   0.0  
gi|73760415 syntaxin binding protein 1 isoform b [Homo sapiens]      1148   0.0  
gi|188528689 syntaxin binding protein 2 isoform a [Homo sapiens]      760   0.0  
gi|188528901 syntaxin binding protein 2 isoform b [Homo sapiens]      751   0.0  
gi|118600975 syntaxin binding protein 3 [Homo sapiens]                586   e-167
gi|18105063 vacuolar protein sorting 45A [Homo sapiens]               115   2e-25
gi|33469966 vesicle transport-related protein isoform a [Homo sa...    80   5e-15
gi|33469978 vesicle transport-related protein isoform b [Homo sa...    64   4e-10
gi|18105056 vacuolar protein sorting 33A [Homo sapiens]                58   3e-08
gi|31542785 sec1 family domain containing 2 [Homo sapiens]             38   0.023
gi|166295179 ELG protein isoform a [Homo sapiens]                      37   0.068
gi|239747793 PREDICTED: protein immuno-reactive with anti-PTH po...    36   0.12 
gi|239741673 PREDICTED: protein immuno-reactive with anti-PTH po...    36   0.12 
gi|4504063 golgin 97 [Homo sapiens]                                    35   0.20 
gi|118918407 spectrin repeat containing, nuclear envelope 2 isof...    35   0.26 
gi|118918403 spectrin repeat containing, nuclear envelope 2 isof...    35   0.26 
gi|93277096 limbin [Homo sapiens]                                      34   0.44 
gi|56961680 coiled-coil domain containing 147 [Homo sapiens]           34   0.44 
gi|56550047 uveal autoantigen with coiled-coil domains and ankyr...    33   0.58 
gi|59850762 uveal autoantigen with coiled-coil domains and ankyr...    33   0.58 
gi|149363685 hypothetical protein LOC23379 [Homo sapiens]              33   0.99 
gi|114155142 nuclear pore complex-associated protein TPR [Homo s...    32   1.3  
gi|209364550 suppressor of S. cerevisiae gcr2 isoform 3 [Homo sa...    31   2.9  
gi|209364547 suppressor of S. cerevisiae gcr2 isoform 2 [Homo sa...    31   2.9  
gi|6005784 suppressor of S. cerevisiae gcr2 isoform 1 [Homo sapi...    31   2.9  
gi|71565160 SMC1 structural maintenance of chromosomes 1-like 2 ...    30   6.4  
gi|31442420 shroom family member 1 [Homo sapiens]                      30   6.4  
gi|237858619 polyamine modulated factor 1 binding protein 1 isof...    30   8.3  
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ...    30   8.3  

>gi|4507297 syntaxin binding protein 1 isoform a [Homo sapiens]
          Length = 603

 Score = 1201 bits (3106), Expect = 0.0
 Identities = 603/603 (100%), Positives = 603/603 (100%)

Query: 1   MAPIGLKAVVGEKIMHDVIKKVKKKGEWKVLVVDQLSMRMLSSCCKMTDIMTEGITIVED 60
           MAPIGLKAVVGEKIMHDVIKKVKKKGEWKVLVVDQLSMRMLSSCCKMTDIMTEGITIVED
Sbjct: 1   MAPIGLKAVVGEKIMHDVIKKVKKKGEWKVLVVDQLSMRMLSSCCKMTDIMTEGITIVED 60

Query: 61  INKRREPLPSLEAVYLITPSEKSVHSLISDFKDPPTAKYRAAHVFFTDSCPDALFNELVK 120
           INKRREPLPSLEAVYLITPSEKSVHSLISDFKDPPTAKYRAAHVFFTDSCPDALFNELVK
Sbjct: 61  INKRREPLPSLEAVYLITPSEKSVHSLISDFKDPPTAKYRAAHVFFTDSCPDALFNELVK 120

Query: 121 SRAAKVIKTLTEINIAFLPYESQVYSLDSADSFQSFYSPHKAQMKNPILERLAEQIATLC 180
           SRAAKVIKTLTEINIAFLPYESQVYSLDSADSFQSFYSPHKAQMKNPILERLAEQIATLC
Sbjct: 121 SRAAKVIKTLTEINIAFLPYESQVYSLDSADSFQSFYSPHKAQMKNPILERLAEQIATLC 180

Query: 181 ATLKEYPAVRYRGEYKDNALLAQLIQDKLDAYKADDPTMGEGPDKARSQLLILDRGFDPS 240
           ATLKEYPAVRYRGEYKDNALLAQLIQDKLDAYKADDPTMGEGPDKARSQLLILDRGFDPS
Sbjct: 181 ATLKEYPAVRYRGEYKDNALLAQLIQDKLDAYKADDPTMGEGPDKARSQLLILDRGFDPS 240

Query: 241 SPVLHELTFQAMSYDLLPIENDVYKYETSGIGEARVKEVLLDEDDDLWIALRHKHIAEVS 300
           SPVLHELTFQAMSYDLLPIENDVYKYETSGIGEARVKEVLLDEDDDLWIALRHKHIAEVS
Sbjct: 241 SPVLHELTFQAMSYDLLPIENDVYKYETSGIGEARVKEVLLDEDDDLWIALRHKHIAEVS 300

Query: 301 QEVTRSLKDFSSSKRMNTGEKTTMRDLSQMLKKMPQYQKELSKYSTHLHLAEDCMKHYQG 360
           QEVTRSLKDFSSSKRMNTGEKTTMRDLSQMLKKMPQYQKELSKYSTHLHLAEDCMKHYQG
Sbjct: 301 QEVTRSLKDFSSSKRMNTGEKTTMRDLSQMLKKMPQYQKELSKYSTHLHLAEDCMKHYQG 360

Query: 361 TVDKLCRVEQDLAMGTDAEGEKIKDPMRAIVPILLDANVSTYDKIRIILLYIFLKNGITE 420
           TVDKLCRVEQDLAMGTDAEGEKIKDPMRAIVPILLDANVSTYDKIRIILLYIFLKNGITE
Sbjct: 361 TVDKLCRVEQDLAMGTDAEGEKIKDPMRAIVPILLDANVSTYDKIRIILLYIFLKNGITE 420

Query: 421 ENLNKLIQHAQIPPEDSEIITNMAHLGVPIVTDSTLRRRSKPERKERISEQTYQLSRWTP 480
           ENLNKLIQHAQIPPEDSEIITNMAHLGVPIVTDSTLRRRSKPERKERISEQTYQLSRWTP
Sbjct: 421 ENLNKLIQHAQIPPEDSEIITNMAHLGVPIVTDSTLRRRSKPERKERISEQTYQLSRWTP 480

Query: 481 IIKDIMEDTIEDKLDTKHYPYISTRSSASFSTTAVSARYGHWHKNKAPGEYRSGPRLIIF 540
           IIKDIMEDTIEDKLDTKHYPYISTRSSASFSTTAVSARYGHWHKNKAPGEYRSGPRLIIF
Sbjct: 481 IIKDIMEDTIEDKLDTKHYPYISTRSSASFSTTAVSARYGHWHKNKAPGEYRSGPRLIIF 540

Query: 541 ILGGVSLNEMRCAYEVTQANGKWEVLIGSTHILTPTKFLMDLRHPDFRESSRVSFEDQAP 600
           ILGGVSLNEMRCAYEVTQANGKWEVLIGSTHILTPTKFLMDLRHPDFRESSRVSFEDQAP
Sbjct: 541 ILGGVSLNEMRCAYEVTQANGKWEVLIGSTHILTPTKFLMDLRHPDFRESSRVSFEDQAP 600

Query: 601 TME 603
           TME
Sbjct: 601 TME 603


>gi|73760415 syntaxin binding protein 1 isoform b [Homo sapiens]
          Length = 594

 Score = 1148 bits (2970), Expect = 0.0
 Identities = 578/583 (99%), Positives = 579/583 (99%)

Query: 1   MAPIGLKAVVGEKIMHDVIKKVKKKGEWKVLVVDQLSMRMLSSCCKMTDIMTEGITIVED 60
           MAPIGLKAVVGEKIMHDVIKKVKKKGEWKVLVVDQLSMRMLSSCCKMTDIMTEGITIVED
Sbjct: 1   MAPIGLKAVVGEKIMHDVIKKVKKKGEWKVLVVDQLSMRMLSSCCKMTDIMTEGITIVED 60

Query: 61  INKRREPLPSLEAVYLITPSEKSVHSLISDFKDPPTAKYRAAHVFFTDSCPDALFNELVK 120
           INKRREPLPSLEAVYLITPSEKSVHSLISDFKDPPTAKYRAAHVFFTDSCPDALFNELVK
Sbjct: 61  INKRREPLPSLEAVYLITPSEKSVHSLISDFKDPPTAKYRAAHVFFTDSCPDALFNELVK 120

Query: 121 SRAAKVIKTLTEINIAFLPYESQVYSLDSADSFQSFYSPHKAQMKNPILERLAEQIATLC 180
           SRAAKVIKTLTEINIAFLPYESQVYSLDSADSFQSFYSPHKAQMKNPILERLAEQIATLC
Sbjct: 121 SRAAKVIKTLTEINIAFLPYESQVYSLDSADSFQSFYSPHKAQMKNPILERLAEQIATLC 180

Query: 181 ATLKEYPAVRYRGEYKDNALLAQLIQDKLDAYKADDPTMGEGPDKARSQLLILDRGFDPS 240
           ATLKEYPAVRYRGEYKDNALLAQLIQDKLDAYKADDPTMGEGPDKARSQLLILDRGFDPS
Sbjct: 181 ATLKEYPAVRYRGEYKDNALLAQLIQDKLDAYKADDPTMGEGPDKARSQLLILDRGFDPS 240

Query: 241 SPVLHELTFQAMSYDLLPIENDVYKYETSGIGEARVKEVLLDEDDDLWIALRHKHIAEVS 300
           SPVLHELTFQAMSYDLLPIENDVYKYETSGIGEARVKEVLLDEDDDLWIALRHKHIAEVS
Sbjct: 241 SPVLHELTFQAMSYDLLPIENDVYKYETSGIGEARVKEVLLDEDDDLWIALRHKHIAEVS 300

Query: 301 QEVTRSLKDFSSSKRMNTGEKTTMRDLSQMLKKMPQYQKELSKYSTHLHLAEDCMKHYQG 360
           QEVTRSLKDFSSSKRMNTGEKTTMRDLSQMLKKMPQYQKELSKYSTHLHLAEDCMKHYQG
Sbjct: 301 QEVTRSLKDFSSSKRMNTGEKTTMRDLSQMLKKMPQYQKELSKYSTHLHLAEDCMKHYQG 360

Query: 361 TVDKLCRVEQDLAMGTDAEGEKIKDPMRAIVPILLDANVSTYDKIRIILLYIFLKNGITE 420
           TVDKLCRVEQDLAMGTDAEGEKIKDPMRAIVPILLDANVSTYDKIRIILLYIFLKNGITE
Sbjct: 361 TVDKLCRVEQDLAMGTDAEGEKIKDPMRAIVPILLDANVSTYDKIRIILLYIFLKNGITE 420

Query: 421 ENLNKLIQHAQIPPEDSEIITNMAHLGVPIVTDSTLRRRSKPERKERISEQTYQLSRWTP 480
           ENLNKLIQHAQIPPEDSEIITNMAHLGVPIVTDSTLRRRSKPERKERISEQTYQLSRWTP
Sbjct: 421 ENLNKLIQHAQIPPEDSEIITNMAHLGVPIVTDSTLRRRSKPERKERISEQTYQLSRWTP 480

Query: 481 IIKDIMEDTIEDKLDTKHYPYISTRSSASFSTTAVSARYGHWHKNKAPGEYRSGPRLIIF 540
           IIKDIMEDTIEDKLDTKHYPYISTRSSASFSTTAVSARYGHWHKNKAPGEYRSGPRLIIF
Sbjct: 481 IIKDIMEDTIEDKLDTKHYPYISTRSSASFSTTAVSARYGHWHKNKAPGEYRSGPRLIIF 540

Query: 541 ILGGVSLNEMRCAYEVTQANGKWEVLIGSTHILTPTKFLMDLR 583
           ILGGVSLNEMRCAYEVTQANGKWEVLIGSTHILTP K L  L+
Sbjct: 541 ILGGVSLNEMRCAYEVTQANGKWEVLIGSTHILTPQKLLDTLK 583


>gi|188528689 syntaxin binding protein 2 isoform a [Homo sapiens]
          Length = 593

 Score =  760 bits (1962), Expect = 0.0
 Identities = 375/587 (63%), Positives = 474/587 (80%), Gaps = 4/587 (0%)

Query: 1   MAPIGLKAVVGEKIMHDVIKKVKKKGEWKVLVVDQLSMRMLSSCCKMTDIMTEGITIVED 60
           MAP GLKAVVGEKI+  VI+ VKK GEWKVL++D  SMR+LSSCCKM+DI+ EGITIVED
Sbjct: 1   MAPSGLKAVVGEKILSGVIRSVKKDGEWKVLIMDHPSMRILSSCCKMSDILAEGITIVED 60

Query: 61  INKRREPLPSLEAVYLITPSEKSVHSLISDFKDPPTAKYRAAHVFFTDSCPDALFNELVK 120
           INKRREP+PSLEA+YL++P+EKSV +LI DF+  PT  Y+AAH+FFTD+CP+ LF+EL +
Sbjct: 61  INKRREPIPSLEAIYLLSPTEKSVQALIKDFQGTPTFTYKAAHIFFTDTCPEPLFSELGR 120

Query: 121 SRAAKVIKTLTEINIAFLPYESQVYSLDSADSFQSFYSPHKAQMKNPILERLAEQIATLC 180
           SR AKV+KTL EI++AFLPYE+QV+SLD+  S  + Y P +A+ +   LE LA+QIATLC
Sbjct: 121 SRLAKVVKTLKEIHLAFLPYEAQVFSLDAPHSTYNLYCPFRAEERTRQLEVLAQQIATLC 180

Query: 181 ATLKEYPAVRYRGEYKDNALLAQLIQDKLDAYKADDPTMGEGPDKARSQLLILDRGFDPS 240
           ATL+EYPA+RYR   +D A LA  +  KL+A+KAD P++GEGP+K RSQLLI+DR  DP 
Sbjct: 181 ATLQEYPAIRYRKGPEDTAQLAHAVLAKLNAFKADTPSLGEGPEKTRSQLLIMDRAADPV 240

Query: 241 SPVLHELTFQAMSYDLLPIENDVYKYETSGIGEARVKEVLLDEDDDLWIALRHKHIAEVS 300
           SP+LHELTFQAM+YDLL IE D Y+YET+G+ EAR K VLLDEDDDLW+ LRH HIA+VS
Sbjct: 241 SPLLHELTFQAMAYDLLDIEQDTYRYETTGLSEAREKAVLLDEDDDLWVELRHMHIADVS 300

Query: 301 QEVTRSLKDFSSSKRMNTGEKTTMRDLSQMLKKMPQYQKELSKYSTHLHLAEDCMKHYQG 360
           ++VT  L+ F  SKR+ T +K  ++DLSQ+LKKMPQYQKEL+KYSTHLHLA+DCMKH++G
Sbjct: 301 KKVTELLRTFCESKRLTT-DKANIKDLSQILKKMPQYQKELNKYSTHLHLADDCMKHFKG 359

Query: 361 TVDKLCRVEQDLAMGTDAEGEKIKDPMRAIVPILLDANVSTYDKIRIILLYIFLKNGITE 420
           +V+KLC VEQDLAMG+DAEGEKIKD M+ IVP+LLDA V  YDKIR++LLYI L+NG++E
Sbjct: 360 SVEKLCSVEQDLAMGSDAEGEKIKDSMKLIVPVLLDAAVPAYDKIRVLLLYILLRNGVSE 419

Query: 421 ENLNKLIQHAQIPPEDSEIITNMAHLGVPIVTDSTLRRRSKPERKERISEQTYQLSRWTP 480
           ENL KLIQHA +    S +I N+  LG  +         S+ E +ER+ E TYQLSRWTP
Sbjct: 420 ENLAKLIQHANVQAH-SSLIRNLEQLGGTVTNPGGSGTSSRLEPRERM-EPTYQLSRWTP 477

Query: 481 IIKDIMEDTIEDKLDTKHYPYISTRSSASFSTTAVSARYGHWHKNKAPGEYRSGPRLIIF 540
           +IKD+MED +ED+LD   +P++S  +  + S  AVSAR+GHWHKNKA  E R+GPRLI++
Sbjct: 478 VIKDVMEDAVEDRLDRNLWPFVSDPAPTASSQAAVSARFGHWHKNKAGIEARAGPRLIVY 537

Query: 541 ILGGVSLNEMRCAYEVTQA-NGKWEVLIGSTHILTPTKFLMDLRHPD 586
           ++GGV+++EMR AYEVT+A  GKWEVLIGS+HILTPT+FL DL+  D
Sbjct: 538 VMGGVAMSEMRAAYEVTRATEGKWEVLIGSSHILTPTRFLDDLKALD 584


>gi|188528901 syntaxin binding protein 2 isoform b [Homo sapiens]
          Length = 590

 Score =  751 bits (1940), Expect = 0.0
 Identities = 373/587 (63%), Positives = 472/587 (80%), Gaps = 7/587 (1%)

Query: 1   MAPIGLKAVVGEKIMHDVIKKVKKKGEWKVLVVDQLSMRMLSSCCKMTDIMTEGITIVED 60
           MAP GLKAVVGEKI+  VI+ VKK GEWKVL++D  SMR+LSSCCKM+DI+ EGITIVED
Sbjct: 1   MAPSGLKAVVGEKILSGVIRSVKKDGEWKVLIMDHPSMRILSSCCKMSDILAEGITIVED 60

Query: 61  INKRREPLPSLEAVYLITPSEKSVHSLISDFKDPPTAKYRAAHVFFTDSCPDALFNELVK 120
           INKRREP+PSLEA+YL++P+EK+   LI DF+  PT  Y+AAH+FFTD+CP+ LF+EL +
Sbjct: 61  INKRREPIPSLEAIYLLSPTEKA---LIKDFQGTPTFTYKAAHIFFTDTCPEPLFSELGR 117

Query: 121 SRAAKVIKTLTEINIAFLPYESQVYSLDSADSFQSFYSPHKAQMKNPILERLAEQIATLC 180
           SR AKV+KTL EI++AFLPYE+QV+SLD+  S  + Y P +A+ +   LE LA+QIATLC
Sbjct: 118 SRLAKVVKTLKEIHLAFLPYEAQVFSLDAPHSTYNLYCPFRAEERTRQLEVLAQQIATLC 177

Query: 181 ATLKEYPAVRYRGEYKDNALLAQLIQDKLDAYKADDPTMGEGPDKARSQLLILDRGFDPS 240
           ATL+EYPA+RYR   +D A LA  +  KL+A+KAD P++GEGP+K RSQLLI+DR  DP 
Sbjct: 178 ATLQEYPAIRYRKGPEDTAQLAHAVLAKLNAFKADTPSLGEGPEKTRSQLLIMDRAADPV 237

Query: 241 SPVLHELTFQAMSYDLLPIENDVYKYETSGIGEARVKEVLLDEDDDLWIALRHKHIAEVS 300
           SP+LHELTFQAM+YDLL IE D Y+YET+G+ EAR K VLLDEDDDLW+ LRH HIA+VS
Sbjct: 238 SPLLHELTFQAMAYDLLDIEQDTYRYETTGLSEAREKAVLLDEDDDLWVELRHMHIADVS 297

Query: 301 QEVTRSLKDFSSSKRMNTGEKTTMRDLSQMLKKMPQYQKELSKYSTHLHLAEDCMKHYQG 360
           ++VT  L+ F  SKR+ T +K  ++DLSQ+LKKMPQYQKEL+KYSTHLHLA+DCMKH++G
Sbjct: 298 KKVTELLRTFCESKRLTT-DKANIKDLSQILKKMPQYQKELNKYSTHLHLADDCMKHFKG 356

Query: 361 TVDKLCRVEQDLAMGTDAEGEKIKDPMRAIVPILLDANVSTYDKIRIILLYIFLKNGITE 420
           +V+KLC VEQDLAMG+DAEGEKIKD M+ IVP+LLDA V  YDKIR++LLYI L+NG++E
Sbjct: 357 SVEKLCSVEQDLAMGSDAEGEKIKDSMKLIVPVLLDAAVPAYDKIRVLLLYILLRNGVSE 416

Query: 421 ENLNKLIQHAQIPPEDSEIITNMAHLGVPIVTDSTLRRRSKPERKERISEQTYQLSRWTP 480
           ENL KLIQHA +    S +I N+  LG  +         S+ E +ER+ E TYQLSRWTP
Sbjct: 417 ENLAKLIQHANVQAH-SSLIRNLEQLGGTVTNPGGSGTSSRLEPRERM-EPTYQLSRWTP 474

Query: 481 IIKDIMEDTIEDKLDTKHYPYISTRSSASFSTTAVSARYGHWHKNKAPGEYRSGPRLIIF 540
           +IKD+MED +ED+LD   +P++S  +  + S  AVSAR+GHWHKNKA  E R+GPRLI++
Sbjct: 475 VIKDVMEDAVEDRLDRNLWPFVSDPAPTASSQAAVSARFGHWHKNKAGIEARAGPRLIVY 534

Query: 541 ILGGVSLNEMRCAYEVTQA-NGKWEVLIGSTHILTPTKFLMDLRHPD 586
           ++GGV+++EMR AYEVT+A  GKWEVLIGS+HILTPT+FL DL+  D
Sbjct: 535 VMGGVAMSEMRAAYEVTRATEGKWEVLIGSSHILTPTRFLDDLKALD 581


>gi|118600975 syntaxin binding protein 3 [Homo sapiens]
          Length = 592

 Score =  586 bits (1511), Expect = e-167
 Identities = 303/589 (51%), Positives = 433/589 (73%), Gaps = 22/589 (3%)

Query: 1   MAPIGLKAVVGEKIMHDVIKKVKKKGEWKVLVVDQLSMRMLSSCCKMTDIMTEGITIVED 60
           +A  GLK+VV +KI   V    KK+GEWK++++D+ + ++L+SCCKMTD++ EGIT+VE+
Sbjct: 5   VAERGLKSVVWQKIKATVFDDCKKEGEWKIMLLDEFTTKLLASCCKMTDLLEEGITVVEN 64

Query: 61  INKRREPLPSLEAVYLITPSEKSVHSLISDFKDPPTAKYRAAHVFFTDSCPDALFNELVK 120
           I K REP+  ++A+Y ITP+ KSV   + DF      KY+AA+++FTD CPD LFN+ +K
Sbjct: 65  IYKNREPVRQMKALYFITPTSKSVDCFLHDFASKSENKYKAAYIYFTDFCPDNLFNK-IK 123

Query: 121 SRAAKVIKTLTEINIAFLPYESQVYSLDSADSFQSFYSPH--KAQMKNPILERLAEQIAT 178
           +  +K I+   EINI+F+P+ESQVY+LD  D+F   YSP    A+ K+ I+E +A+QI T
Sbjct: 124 ASCSKSIRRCKEINISFIPHESQVYTLDVPDAFYYCYSPDPGNAKGKDAIMETMADQIVT 183

Query: 179 LCATLKEYPAVRYRGEYKDNAL-LAQLIQDKL-DAYKADDPTMGEGPDKARSQLLILDRG 236
           +CATL E P VRY+ +  DNA  LAQL++ KL D YK D+ ++ +G  K  SQLLI+DRG
Sbjct: 184 VCATLDENPGVRYKSKPLDNASKLAQLVEKKLEDYYKIDEKSLIKG--KTHSQLLIIDRG 241

Query: 237 FDPSSPVLHELTFQAMSYDLLPIENDVYKYETSGIGEARVKEVLLDEDDDLWIALRHKHI 296
           FDP S VLHELTFQAM+YDLLPIEND YKY+T G    + KE +L+E+DDLW+ +RH+HI
Sbjct: 242 FDPVSTVLHELTFQAMAYDLLPIENDTYKYKTDG----KEKEAILEEEDDLWVRIRHRHI 297

Query: 297 AEVSQEVTRSLKDFSSSKRMNTGEKTTMRDLSQMLKKMPQYQKELSKYSTHLHLAEDCMK 356
           A V +E+ + +K+ SS+K+   G KT++  L+Q++KKMP ++K+++K   HL+LAEDCM 
Sbjct: 298 AVVLEEIPKLMKEISSTKKATEG-KTSLSALTQLMKKMPHFRKQITKQVVHLNLAEDCMN 356

Query: 357 HYQGTVDKLCRVEQDLAMGTDAEGEKIKDPMRAIVPILLDANVSTYDKIRIILLYIFLKN 416
            ++  ++KLC+ EQDLA+GTDAEG+K+KD MR ++P+LL+ N    DKIR ILLYIF  N
Sbjct: 357 KFKLNIEKLCKTEQDLALGTDAEGQKVKDSMRVLLPVLLNKNHDNCDKIRAILLYIFSIN 416

Query: 417 GITEENLNKLIQHAQIPPEDSEIITNMAHLGVPIVTDSTLRRRSKPERKERISEQTYQLS 476
           G TEENL++LIQ+ +I  E S++I N ++LGVPIV  S   ++ KP RK+R +E+T+QLS
Sbjct: 417 GTTEENLDRLIQNVKIENE-SDMIRNWSYLGVPIVPQS---QQGKPLRKDRSAEETFQLS 472

Query: 477 RWTPIIKDIMEDTIEDKLDTKHYPYISTRSSASFSTTAVSARYGHWHKNKAP--GEYRSG 534
           RWTP IKDIMED I+++LD+K +PY S   +    + AVSAR     K +A    + ++G
Sbjct: 473 RWTPFIKDIMEDAIDNRLDSKEWPYCSQCPAVWNGSGAVSAR----QKPRANYLEDRKNG 528

Query: 535 PRLIIFILGGVSLNEMRCAYEVTQANGKWEVLIGSTHILTPTKFLMDLR 583
            +LI+F++GG++ +E+RCAYEV+QA+   EV+IGSTH+LTP K L D++
Sbjct: 529 SKLIVFVIGGITYSEVRCAYEVSQAHKSCEVIIGSTHVLTPKKLLDDIK 577


>gi|18105063 vacuolar protein sorting 45A [Homo sapiens]
          Length = 570

 Score =  115 bits (287), Expect = 2e-25
 Identities = 119/587 (20%), Positives = 262/587 (44%), Gaps = 67/587 (11%)

Query: 29  KVLVVDQLSMRMLSSCCKMTDIMTEGITIVEDINKR-REPLPSLEAVYLITPSEKSVHSL 87
           KVL++D+ +  ++S     ++I+ + + + E I+ + RE +  L+A+  + P++++V  +
Sbjct: 23  KVLLMDKETTGIVSMVYTQSEILQKEVYLFERIDSQNREIMKHLKAICFLRPTKENVDYI 82

Query: 88  ISDFKDPPTAKYRAAHVFFTDSCPDALFNELVKSRAAKVIKTLTEINIAFLPYESQVYSL 147
           I + + P   KY    ++F++    +    L ++   +V+  + E    ++     ++SL
Sbjct: 83  IQELRRP---KYTIYFIYFSNVISKSDVKSLAEADEQEVVAEVQEFYGDYIAVNPHLFSL 139

Query: 148 DSADSFQSF-YSPHKAQMKNPILERLAEQIATLCATLKEYPAVRYRGEYKDNALLAQLIQ 206
           +     Q   + P +       L R  + +  L  +LK+ P +RY+   +    LA+ ++
Sbjct: 140 NILGCCQGRNWDPAQ-------LSRTTQGLTALLLSLKKCPMIRYQLSSEAAKRLAECVK 192

Query: 207 DKLDA-YKADDPTMGEGPDKARSQLLILDRGFDPSSPVLHELTFQAMSYDLLPIEND-VY 264
             +   Y+  +    E P      LLILDR  D  +P+L++ T+QAM ++LL I N+ + 
Sbjct: 193 QVITKEYELFEFRRTEVPPL----LLILDRCDDAITPLLNQWTYQAMVHELLGINNNRID 248

Query: 265 KYETSGIGEARVKEVLLDEDDDLWIALRHKHIAEVSQEVTRSLKDFSSSKRMNTGEKTTM 324
                GI +   + VL  E+D+ +    + + AE+   +   ++DF   K     +  ++
Sbjct: 249 LSRVPGISKDLREVVLSAENDEFYANNMYLNFAEIGSNIKNLMEDFQKKKPKEQQKLESI 308

Query: 325 RDLSQMLKKMPQYQKELSKYSTHLHLAEDCMKHY-QGTVDKLCRVEQDLAMGTDAEGEKI 383
            D+   ++  PQ++K     S H+ +  +  +   +  + ++  VEQ+LA   D      
Sbjct: 309 ADMKAFVENYPQFKKMSGTVSKHVTVVGELSRLVSERNLLEVSEVEQELACQNDH----- 363

Query: 384 KDPMRAIVPILLDANVSTYDKIRIILLYIFLKNGITEENLNKL---IQHAQIPPEDSEII 440
              ++ I  +L +  V+ +D  R+++LY       +  +L  L   +++  +  +  +++
Sbjct: 364 SSALQNIKRLLQNPKVTEFDAARLVMLYALHYERHSSNSLPGLMMDLRNKGVSEKYRKLV 423

Query: 441 TNMAHLGVPIVTDSTLRRRSKPERKERISEQTYQ--------LSRWTPIIKDIMEDTIED 492
           + +   G   V  S L     P+    I++Q  +         ++  P + + ++  I+ 
Sbjct: 424 SAVVEYGGKRVRGSDL---FSPKDAVAITKQFLKGLKGVENVYTQHQPFLHETLDHLIKG 480

Query: 493 KLDTKHYPYISTRSSASFSTTAVSARYGHWHKNKAPGEYRSGPR-LIIFILGGVSLNEMR 551
           +L    YPY+                         P   R  P+ +I+F++GG +  E  
Sbjct: 481 RLKENLYPYL------------------------GPSTLRDRPQDIIVFVIGGATYEEAL 516

Query: 552 CAYEVTQANGKWEVLIGSTHILTPTKFLMDL----RHPDFRESSRVS 594
             Y + +      +++G T +     FL ++     H   +ESS+V+
Sbjct: 517 TVYNLNRTTPGVRIVLGGTTVHNTKSFLEEVLASGLHSRSKESSQVT 563


>gi|33469966 vesicle transport-related protein isoform a [Homo
           sapiens]
          Length = 642

 Score = 80.1 bits (196), Expect = 5e-15
 Identities = 89/455 (19%), Positives = 194/455 (42%), Gaps = 62/455 (13%)

Query: 4   IGLKAVVGEKIMHDVIKKVKKKGEWKVLVVDQLSMRMLSSCCKMTDIMTEGITIVEDINK 63
           + LK ++   + H  IK    +  WKVL+ D+    ++S    + ++   GIT+   ++ 
Sbjct: 21  VALKRMLNFNVPH--IKNSTGEPVWKVLIYDRFGQDIISPLLSVKELRDMGITLHLLLHS 78

Query: 64  RREPLPSLEAVYLITPSEKSVHSLISDFKDPPTAKYRAAHV-FFTDSCPDALFNELVKSR 122
            R+P+P + AVY + P+E+++  +  D ++     Y    +   + S  + + N  + + 
Sbjct: 79  DRDPIPDVPAVYFVMPTEENIDRMCQDLRNQLYESYYLNFISAISRSKLEDIANAALAAS 138

Query: 123 AAKVIKTLTEINIAFLPYESQVYSLDSAD----SFQSFYSPHKAQMK-NPILERLAEQIA 177
           A   +  + +  + F+  E  ++ L + +    S+++   P     +   +++ + + + 
Sbjct: 139 AVTQVAKVFDQYLNFITLEDDMFVLCNQNKELVSYRAINRPDITDTEMETVMDTIVDSLF 198

Query: 178 TLCATLKEYPAVRYRGEYKDNALLAQLIQDKLDAYKADD-----------PTMGEGPDKA 226
               TL   P +R           A+++  KLD    ++            T+G G    
Sbjct: 199 CFFVTLGAVPIIRC-----SRGTAAEMVAVKLDKKLRENLRDARNSLFTGDTLGAGQFSF 253

Query: 227 RSQLLIL-DRGFDPSSPVLHELTFQAMSYDLLPIE-NDVYKYETSGIGEA---------R 275
           +  LL+L DR  D ++P+ H  T+QA+ +D+L    N V   E+SG+  +          
Sbjct: 254 QRPLLVLVDRNIDLATPLHHTWTYQALVHDVLDFHLNRVNLEESSGVENSPAGARPKRKN 313

Query: 276 VKEVLLDEDDDLWIALRHKHIAEVSQEVTRSLKDFSSS----KRMNT---------GEKT 322
            K   L   D  W   +     EV++ V + L+ + +     KR+ +         G  +
Sbjct: 314 KKSYDLTPVDKFWQKHKGSPFPEVAESVQQELESYRAQEDEVKRLKSIMGLEGEDEGAIS 373

Query: 323 TMRD----LSQMLKKMPQYQKELSKYSTHLHLAEDCMKHYQG-TVDKLCRVEQDLAMGTD 377
            + D    L+  +  +P+  ++      H ++A   ++H +   +D     E+ +   T 
Sbjct: 374 MLSDNTAKLTSAVSSLPELLEKKRLIDLHTNVATAVLEHIKARKLDVYFEYEEKIMSKTT 433

Query: 378 AEGEKIKDPMRAIVPILLDANVST-YDKIRIILLY 411
            +        ++++ I+ D +  T  DK+R+ L+Y
Sbjct: 434 LD--------KSLLDIISDPDAGTPEDKMRLFLIY 460


>gi|33469978 vesicle transport-related protein isoform b [Homo
           sapiens]
          Length = 575

 Score = 63.9 bits (154), Expect = 4e-10
 Identities = 78/405 (19%), Positives = 171/405 (42%), Gaps = 60/405 (14%)

Query: 54  GITIVEDINKRREPLPSLEAVYLITPSEKSVHSLISDFKDPPTAKYRAAHV-FFTDSCPD 112
           GIT+   ++  R+P+P + AVY + P+E+++  +  D ++     Y    +   + S  +
Sbjct: 2   GITLHLLLHSDRDPIPDVPAVYFVMPTEENIDRMCQDLRNQLYESYYLNFISAISRSKLE 61

Query: 113 ALFNELVKSRAAKVIKTLTEINIAFLPYESQVYSLDSAD----SFQSFYSPHKAQMK-NP 167
            + N  + + A   +  + +  + F+  E  ++ L + +    S+++   P     +   
Sbjct: 62  DIANAALAASAVTQVAKVFDQYLNFITLEDDMFVLCNQNKELVSYRAINRPDITDTEMET 121

Query: 168 ILERLAEQIATLCATLKEYPAVRYRGEYKDNALLAQLIQDKLDAYKADD----------- 216
           +++ + + +     TL   P +R           A+++  KLD    ++           
Sbjct: 122 VMDTIVDSLFCFFVTLGAVPIIRC-----SRGTAAEMVAVKLDKKLRENLRDARNSLFTG 176

Query: 217 PTMGEGPDKARSQLLIL-DRGFDPSSPVLHELTFQAMSYDLLPIE-NDVYKYETSGIGEA 274
            T+G G    +  LL+L DR  D ++P+ H  T+QA+ +D+L    N V   E+SG+  +
Sbjct: 177 DTLGAGQFSFQRPLLVLVDRNIDLATPLHHTWTYQALVHDVLDFHLNRVNLEESSGVENS 236

Query: 275 ---------RVKEVLLDEDDDLWIALRHKHIAEVSQEVTRSLKDFSSS----KRMNT--- 318
                      K   L   D  W   +     EV++ V + L+ + +     KR+ +   
Sbjct: 237 PAGARPKRKNKKSYDLTPVDKFWQKHKGSPFPEVAESVQQELESYRAQEDEVKRLKSIMG 296

Query: 319 ------GEKTTMRD----LSQMLKKMPQYQKELSKYSTHLHLAEDCMKHYQG-TVDKLCR 367
                 G  + + D    L+  +  +P+  ++      H ++A   ++H +   +D    
Sbjct: 297 LEGEDEGAISMLSDNTAKLTSAVSSLPELLEKKRLIDLHTNVATAVLEHIKARKLDVYFE 356

Query: 368 VEQDLAMGTDAEGEKIKDPMRAIVPILLDANVST-YDKIRIILLY 411
            E+ +   T  +        ++++ I+ D +  T  DK+R+ L+Y
Sbjct: 357 YEEKIMSKTTLD--------KSLLDIISDPDAGTPEDKMRLFLIY 393


>gi|18105056 vacuolar protein sorting 33A [Homo sapiens]
          Length = 596

 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 96/490 (19%), Positives = 192/490 (39%), Gaps = 66/490 (13%)

Query: 132 EINIAFLPYESQVYSLDSADSFQSFYSPHKAQMKNPILERLAEQIATLCATLKEYPAVRY 191
           E ++  +P++  + S++S  +F+  Y     +     L   A+ + TL A     P +  
Sbjct: 139 EYSLDLIPFDGDLLSMESEGAFKECY----LEGDQTSLYHAAKGLMTLQALYGTIPQIFG 194

Query: 192 RGEYKDNALLAQLIQDKLDAYKADDPTMGEGPDKARSQLLILDRGFDPSSPVLHELTFQA 251
           +GE       A+ + + +   K +              LL+LDR  D  +P+  +LT++ 
Sbjct: 195 KGE------CARQVANMMIRMKREFTGSQNSIFPVFDNLLLLDRNVDLLTPLATQLTYEG 248

Query: 252 MSYDLLPIENDVYKY-------ETSGIG----EARVKEVLLDEDDDLWIALRHKHIAEVS 300
           +  ++  I+N   K        +  G G        K++ L+  ++L+  +R K+   V 
Sbjct: 249 LIDEIYGIQNSYVKLPPEKFAPKKQGDGGKDLPTEAKKLQLNSAEELYAEIRDKNFNAVG 308

Query: 301 QEVTRSLKDFSSSKRMNTGEKTTMRDLSQMLKKMPQYQKELSKYSTHLHLAE--DCMKHY 358
             +++  K  S++       K T+ ++ Q + ++P  Q      + H  +AE    +   
Sbjct: 309 SVLSKKAKIISAAFEERHNAK-TVGEIKQFVSQLPHMQAARGSLANHTSIAELIKDVTTS 367

Query: 359 QGTVDKLCRVEQDLAMGTDAEGEKIKDPMRAIVPILLDANVSTYDKIRIILLYIFLKNGI 418
           +   DKL  VEQ+   G D       D +   +   +    S    +R++ L     +G+
Sbjct: 368 EDFFDKL-TVEQEFMSGIDT------DKVNNYIEDCIAQKHSLIKVLRLVCLQSVCNSGL 420

Query: 419 TEENLNKLIQHAQIPPEDSEIIT--NMAHLGV-----------PIVTDSTLRRRSKPERK 465
            ++ L+   +          I+T  N+   G+           P +   TLR       +
Sbjct: 421 KQKVLDYYKREILQTYGYEHILTLHNLEKAGLLKPQTGGRNNYPTIR-KTLRLWMDDVNE 479

Query: 466 ERISEQTYQLSRWTPIIKDIME-------DTIEDKLDTKHYPYISTRSSASFSTTAVSAR 518
           +  ++ +Y  S + P+   + +        +IE+ L     P+   R             
Sbjct: 480 QNPTDISYVYSGYAPLSVRLAQLLSRPGWRSIEEVLRILPGPHFEERQPLPTGL------ 533

Query: 519 YGHWHKNKAPGEYRSGPRLIIFILGGVSLNEMRCAYEVTQ-ANGKWEVLIGSTHILTPTK 577
                K + PGE R     +IF LGGV+  E+     ++Q  +G  E +I +T ++  T 
Sbjct: 534 ----QKKRQPGENRV---TLIFFLGGVTFAEIAALRFLSQLEDGGTEYVIATTKLMNGTS 586

Query: 578 FLMDLRHPDF 587
           ++  L    F
Sbjct: 587 WIEALMEKPF 596


>gi|31542785 sec1 family domain containing 2 [Homo sapiens]
          Length = 684

 Score = 38.1 bits (87), Expect = 0.023
 Identities = 82/357 (22%), Positives = 147/357 (41%), Gaps = 75/357 (21%)

Query: 287 LWIALRHKHIAEVSQEVTRSLKDFSSSK----RMNTGEKTTMRDLSQMLKKMPQYQKELS 342
           LW AL +    E   EV R L + +S +    +M+ G  T      Q++  +  ++  L 
Sbjct: 343 LWEALLNTKHKEAVMEVRRHLVEAASRENLPIKMSMGRVTP----GQLMSYIQLFKNNLK 398

Query: 343 KYSTHLHLAE------DCMKHYQGTV-DKLCRVEQDL--AMGTDAEGEKIKDPMRAIVPI 393
               H  L +        +KH Q    D     E+ L  ++G  A    +   +  I P+
Sbjct: 399 ALMNHCGLLQLGLATAQTLKHPQTAKWDNFLAFERLLLQSIGESAMSVVLNQLLPMIKPV 458

Query: 394 LLDANVS-TYDKIRIILLYIFLKNGI---------TEENLNKLIQHAQIPPEDSEI---- 439
               N   + +++ I+L+YI+   G           EE + K +  AQ+  E+S +    
Sbjct: 459 TQRTNEDYSPEELLILLIYIYSVTGELTVDKDLCEAEEKVKKAL--AQVFCEESGLSPLL 516

Query: 440 --IT------NMAHLGVPIVTD---STLR----RRSKPERKERI---SEQTYQLSRWTPI 481
             IT      N+      I  D   ++LR     RS  ++ + +      T+Q S + P+
Sbjct: 517 QKITDWDSSINLTFHKSKIAVDELFTSLRDIAGARSLLKQFKSVYVPGNHTHQAS-YKPL 575

Query: 482 IKDIMEDTIE----DKLDTKHYPYISTRSSASFSTTAVSARYGHWHK--NKAPGEYRSGP 535
           +K ++E+       D +D +H         +S  T  +   +  + K     P +Y   P
Sbjct: 576 LKQVVEEIFHPERPDSVDIEHM--------SSGLTDLLKTGFSMFMKVSRPHPSDY---P 624

Query: 536 RLIIFILGGVSLNEMRCAYE-VTQANGKWEVLIGSTHILTPTK-----FLMDLRHPD 586
            LI+F++GGV+++E++   + V       +V++ ST +L P       F  D  HPD
Sbjct: 625 LLILFVVGGVTVSEVKMVKDLVASLKPGTQVIVLSTRLLKPLNIPELLFATDRLHPD 681


>gi|166295179 ELG protein isoform a [Homo sapiens]
          Length = 620

 Score = 36.6 bits (83), Expect = 0.068
 Identities = 26/105 (24%), Positives = 49/105 (46%), Gaps = 15/105 (14%)

Query: 49  DIMTEGITIVEDINKRREPLPSLEAVYLITPSEKSVHSLISDFKDPPTAKYRAAHVFFTD 108
           ++    + +  D+ K+  P   LE +Y+    E S   + S FK+     Y  AH+ + D
Sbjct: 103 NLAQRNVALDRDMMKKAIPKVRLETIYICGVDEMSTQDVFSYFKE-----YPPAHIEWLD 157

Query: 109 --SCPDALFNELVKSRAAKVIKTLTEINIAFLPYESQVYSLDSAD 151
             SC     +E+  +RA         IN++ LP + ++ S D+++
Sbjct: 158 DTSCNVVWLDEMTATRAL--------INMSSLPAQDKIRSRDASE 194


>gi|239747793 PREDICTED: protein immuno-reactive with anti-PTH
           polyclonal antibodies [Homo sapiens]
          Length = 868

 Score = 35.8 bits (81), Expect = 0.12
 Identities = 33/147 (22%), Positives = 59/147 (40%), Gaps = 17/147 (11%)

Query: 238 DPSSPVLHELTFQAMSYDLLPIENDVYKYETSGIGEARVKEVLLDEDDDLWIALRHKHIA 297
           D    +LHE          L +E D  K +       +  E++  + +DL  AL+     
Sbjct: 455 DEKEDLLHENRLMQDEIARLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALKRNE-- 512

Query: 298 EVSQEVTRSLKDFSSSKRMNTGEKTTMRD-LSQMLKKMPQYQKELSKYSTHLHLA----- 351
              + +  ++  +S      T E TT+R  L +  +   + + E+  Y   L+ A     
Sbjct: 513 ---ETLAETIACYSGQLAALTDENTTLRSKLEKQRESGQRLETEMQSYRCRLNAALCDHD 569

Query: 352 ------EDCMKHYQGTVDKLCRVEQDL 372
                  D    +QGTVDK C ++++L
Sbjct: 570 QSHSSKRDQELAFQGTVDKCCHLQENL 596


>gi|239741673 PREDICTED: protein immuno-reactive with anti-PTH
            polyclonal antibodies [Homo sapiens]
          Length = 1430

 Score = 35.8 bits (81), Expect = 0.12
 Identities = 33/147 (22%), Positives = 59/147 (40%), Gaps = 17/147 (11%)

Query: 238  DPSSPVLHELTFQAMSYDLLPIENDVYKYETSGIGEARVKEVLLDEDDDLWIALRHKHIA 297
            D    +LHE          L +E D  K +       +  E++  + +DL  AL+     
Sbjct: 1017 DEKEDLLHENRLMQDEIARLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALKRNE-- 1074

Query: 298  EVSQEVTRSLKDFSSSKRMNTGEKTTMRD-LSQMLKKMPQYQKELSKYSTHLHLA----- 351
               + +  ++  +S      T E TT+R  L +  +   + + E+  Y   L+ A     
Sbjct: 1075 ---ETLAETIACYSGQLAALTDENTTLRSKLEKQRESGQRLETEMQSYRCRLNAALCDHD 1131

Query: 352  ------EDCMKHYQGTVDKLCRVEQDL 372
                   D    +QGTVDK C ++++L
Sbjct: 1132 QSHSSKRDQELAFQGTVDKCCHLQENL 1158


>gi|4504063 golgin 97 [Homo sapiens]
          Length = 767

 Score = 35.0 bits (79), Expect = 0.20
 Identities = 50/222 (22%), Positives = 103/222 (46%), Gaps = 35/222 (15%)

Query: 148 DSADSFQSFYSPHKAQMKNPILERLAEQIATLCATLKEYPA-VRYRGEYKDNALLA---- 202
           DS D F S  S  +  + + +L R  EQI  L A L +Y   VR   + K+   +A    
Sbjct: 40  DSGDDFASDGSSSREDLSSQLLRR-NEQIRKLEARLSDYAEQVRNLQKIKEKLEIALEKH 98

Query: 203 -----QLIQDKLDAYKADDPTMGEG-------PDKARSQLLI-LDRGFDPSSPVLHELTF 249
                +  Q++ + ++A+   M EG        D+  S+ +  L++  +  +  L E+  
Sbjct: 99  QDSSMRKFQEQNETFQANRAKMAEGLALALARKDQEWSEKMDQLEKEKNILTAQLQEMKN 158

Query: 250 QAMSYDLLPIENDVYKYETSGIGE---ARVKEVLLDEDDDLWIALRHKHIAEVSQEVTRS 306
           Q+M+      E D    E  G  +   +++K +LL +++ L      + +   ++E++R+
Sbjct: 159 QSMNLFQRRDEMD----ELEGFQQQELSKIKHMLLKKEESL--GKMEQELEARTRELSRT 212

Query: 307 LKDFSSSKRMNTGEKTTMRDLSQMLKKMPQYQKELSKYSTHL 348
            ++  +S +M++       DLSQ L+++ ++   L +   H+
Sbjct: 213 QEELMNSNQMSS-------DLSQKLEELQRHYSTLEEQRDHV 247


>gi|118918407 spectrin repeat containing, nuclear envelope 2 isoform 5
            [Homo sapiens]
          Length = 6907

 Score = 34.7 bits (78), Expect = 0.26
 Identities = 39/163 (23%), Positives = 63/163 (38%), Gaps = 25/163 (15%)

Query: 224  DKARSQLLILDRGFDPSSPVLHELTFQAMSYDLLPIENDVYKYETSGIGEARVKEVLLDE 283
            D    Q+ I +R  +P + VL EL      +DL  ++N + KY+T   G           
Sbjct: 1266 DSIAKQIEICNRLEEPGNFVLKELH----PFDLHAMQNIILKYKTQFEGM---------- 1311

Query: 284  DDDLWIALRHKHIAEVSQEVTRSLKDFSSSKRMNTGEKTTMRDLSQMLKKMPQYQKELSK 343
                       H  + S++  ++L+DF +S R        + DLS    ++ Q      K
Sbjct: 1312 ----------NHRVQRSEDTLKALEDFLASLRTAKLSAEPVTDLSASDTQVAQENTLTVK 1361

Query: 344  YST-HLHLAEDCMKHYQGTVDKLCRVEQDLAMGTDAEGEKIKD 385
                 +HL +D  KH    +  L    +D   G D   E + D
Sbjct: 1362 NKEGEIHLMKDKAKHLDKCLKMLDMSFKDAERGDDTSCENLLD 1404


>gi|118918403 spectrin repeat containing, nuclear envelope 2 isoform 1
            [Homo sapiens]
          Length = 6885

 Score = 34.7 bits (78), Expect = 0.26
 Identities = 39/163 (23%), Positives = 63/163 (38%), Gaps = 25/163 (15%)

Query: 224  DKARSQLLILDRGFDPSSPVLHELTFQAMSYDLLPIENDVYKYETSGIGEARVKEVLLDE 283
            D    Q+ I +R  +P + VL EL      +DL  ++N + KY+T   G           
Sbjct: 1266 DSIAKQIEICNRLEEPGNFVLKELH----PFDLHAMQNIILKYKTQFEGM---------- 1311

Query: 284  DDDLWIALRHKHIAEVSQEVTRSLKDFSSSKRMNTGEKTTMRDLSQMLKKMPQYQKELSK 343
                       H  + S++  ++L+DF +S R        + DLS    ++ Q      K
Sbjct: 1312 ----------NHRVQRSEDTLKALEDFLASLRTAKLSAEPVTDLSASDTQVAQENTLTVK 1361

Query: 344  YST-HLHLAEDCMKHYQGTVDKLCRVEQDLAMGTDAEGEKIKD 385
                 +HL +D  KH    +  L    +D   G D   E + D
Sbjct: 1362 NKEGEIHLMKDKAKHLDKCLKMLDMSFKDAERGDDTSCENLLD 1404


>gi|93277096 limbin [Homo sapiens]
          Length = 1308

 Score = 33.9 bits (76), Expect = 0.44
 Identities = 46/233 (19%), Positives = 99/233 (42%), Gaps = 37/233 (15%)

Query: 263 VYKYETSGIGEARVKEVLLDEDDDLWIALRHKHIAEVSQE--------VTRSLKDFSSSK 314
           + K+E +G  +    E+LL+       +++ K   ++ QE        +T+  ++     
Sbjct: 624 IQKHERAGYLDEDQMEMLLERAQTEVFSIKQKLDNDLKQEKKKLHQKLITKRRRELLQKH 683

Query: 315 RMNTGEKTTMRDLSQMLKKMPQYQKELSKYSTHLHLAEDCMKHYQGTVDKLC-RVEQ--- 370
           R    E+ ++ +  + ++   QY          LH     M+ +  T+++L  R++Q   
Sbjct: 684 REQRREQASVGEAFRTVEDAGQY----------LHQKRSLMEEHGATLEELQERLDQAAL 733

Query: 371 -DLAMGTDAEGEKIKDPMRAIVPILLDANVSTYDKIRIILLYIFLKNGITEENLNKLIQH 429
            DL   T +  EK  D +R      L  +  T + ++  + ++FL+  + E       + 
Sbjct: 734 DDLRTLTLSLFEKATDELRR-----LQNSAMTQELLKRGVPWLFLQQILEEHGKEMAARA 788

Query: 430 AQIPPEDSEIITNMAHLGVPIVTDSTLRRRSKPERKERISEQTYQLSRWTPII 482
            Q+  E+ +        GV      ++R+R K +  E ++E+  +L RW  +I
Sbjct: 789 EQLEGEERD----RDQEGV-----QSVRQRLKDDAPEAVTEEQAELRRWEHLI 832


>gi|56961680 coiled-coil domain containing 147 [Homo sapiens]
          Length = 872

 Score = 33.9 bits (76), Expect = 0.44
 Identities = 31/120 (25%), Positives = 52/120 (43%), Gaps = 20/120 (16%)

Query: 253 SYDLLPIENDVYKYETSGIGEARVKEVLLDEDDDLWIALRHKHIAEVSQEVTRSLKDFSS 312
           +Y+L+   + + K   S   E   KE+LL E + L++ L+H    +   E    LK +  
Sbjct: 723 AYELIQKIHTLQKRLISKTEEVVEKELLLQEKEKLYMELKHVLARQPGPEAAEQLKLY-- 780

Query: 313 SKRMNTGEKTTMRDLSQMLKKMPQYQKELSKYSTHLHLAEDCMKHYQGTVDKLCRVEQDL 372
                   + T+ D  Q LK +          S+ L++ E   K Y+  V+KL    Q+L
Sbjct: 781 --------RRTLHDKKQQLKVL----------SSELNMYEVQSKEYKYEVEKLTNELQNL 822


>gi|56550047 uveal autoantigen with coiled-coil domains and ankyrin
            repeats isoform 2 [Homo sapiens]
          Length = 1403

 Score = 33.5 bits (75), Expect = 0.58
 Identities = 48/244 (19%), Positives = 100/244 (40%), Gaps = 17/244 (6%)

Query: 260  ENDVYKYETSGIG-EARVKEVLLDEDDDLWIALRHKHIAEVSQEVTRSLKDFSS--SKRM 316
            END  K E   +  + R K VL+++  ++  AL  K     + E+ + LKD S   ++  
Sbjct: 1016 ENDKLKKEIFTLQKDLRDKTVLIEKSHEMERALSRK-----TDELNKQLKDLSQKYTEVK 1070

Query: 317  NTGEKTTMRDLSQMLKKMPQYQKELSKYSTHLHLAEDCMKHYQGTVDKLCRVEQDLAMGT 376
            N  EK    +  Q   ++   Q  L K    L   E   K   GT++ L    + +    
Sbjct: 1071 NVKEKLVEENAKQT-SEILAVQNLLQKQHVPLEQVEALKKSLNGTIENLKEELKSMQRCY 1129

Query: 377  DAEGEKI-------KDPMRAIVPILLDANVSTYDKIRIILLYIFLKNGITEENLNKLIQH 429
            + E + +       ++   + VP+     +    +  + ++   L+    EE+ NK+ + 
Sbjct: 1130 EKEQQTVTKLHQLLENQKNSSVPLAEHLQIKEAFEKEVGIIKASLREK-EEESQNKMEEV 1188

Query: 430  AQIPPEDSEIITNMAHLGVPIVTDSTLRRRSKPERKERISEQTYQLSRWTPIIKDIMEDT 489
            +++  E       +  L    V D +  + +K + + +IS    +L+      +++ E+ 
Sbjct: 1189 SKLQSEVQNTKQALKKLETREVVDLSKYKATKSDLETQISSLNEKLANLNRKYEEVCEEV 1248

Query: 490  IEDK 493
            +  K
Sbjct: 1249 LHAK 1252


>gi|59850762 uveal autoantigen with coiled-coil domains and ankyrin
            repeats isoform 1 [Homo sapiens]
          Length = 1416

 Score = 33.5 bits (75), Expect = 0.58
 Identities = 48/244 (19%), Positives = 100/244 (40%), Gaps = 17/244 (6%)

Query: 260  ENDVYKYETSGIG-EARVKEVLLDEDDDLWIALRHKHIAEVSQEVTRSLKDFSS--SKRM 316
            END  K E   +  + R K VL+++  ++  AL  K     + E+ + LKD S   ++  
Sbjct: 1029 ENDKLKKEIFTLQKDLRDKTVLIEKSHEMERALSRK-----TDELNKQLKDLSQKYTEVK 1083

Query: 317  NTGEKTTMRDLSQMLKKMPQYQKELSKYSTHLHLAEDCMKHYQGTVDKLCRVEQDLAMGT 376
            N  EK    +  Q   ++   Q  L K    L   E   K   GT++ L    + +    
Sbjct: 1084 NVKEKLVEENAKQT-SEILAVQNLLQKQHVPLEQVEALKKSLNGTIENLKEELKSMQRCY 1142

Query: 377  DAEGEKI-------KDPMRAIVPILLDANVSTYDKIRIILLYIFLKNGITEENLNKLIQH 429
            + E + +       ++   + VP+     +    +  + ++   L+    EE+ NK+ + 
Sbjct: 1143 EKEQQTVTKLHQLLENQKNSSVPLAEHLQIKEAFEKEVGIIKASLREK-EEESQNKMEEV 1201

Query: 430  AQIPPEDSEIITNMAHLGVPIVTDSTLRRRSKPERKERISEQTYQLSRWTPIIKDIMEDT 489
            +++  E       +  L    V D +  + +K + + +IS    +L+      +++ E+ 
Sbjct: 1202 SKLQSEVQNTKQALKKLETREVVDLSKYKATKSDLETQISSLNEKLANLNRKYEEVCEEV 1261

Query: 490  IEDK 493
            +  K
Sbjct: 1262 LHAK 1265


>gi|149363685 hypothetical protein LOC23379 [Homo sapiens]
          Length = 2266

 Score = 32.7 bits (73), Expect = 0.99
 Identities = 23/112 (20%), Positives = 54/112 (48%), Gaps = 3/112 (2%)

Query: 281 LDEDDDLWIALRHKHIA--EVSQEVTRSLKDFSSSKRMNTGEKTTMRDLSQMLKKMPQYQ 338
           L+E  +  I L+ K I    +  E  +   +   ++R N+     + ++ Q +  + + Q
Sbjct: 30  LNEYVEALITLKQKIINTDNLLTEYQKKCDELQFARRENSNLHHQVEEMLQKISPLQKCQ 89

Query: 339 KELSKYSTHLHLAEDCMKHYQGTVDKLCRVEQDLAMGTDAEGEKIKDPMRAI 390
           +EL      L   +  +K YQ T  +  RV+++  + +DA+ +K++  ++ +
Sbjct: 90  EELGSLKAELEEKKSSLKLYQDTHQEYARVKEE-CLKSDAQKKKLEAKVKKL 140


>gi|114155142 nuclear pore complex-associated protein TPR [Homo
            sapiens]
          Length = 2363

 Score = 32.3 bits (72), Expect = 1.3
 Identities = 27/143 (18%), Positives = 69/143 (48%), Gaps = 9/143 (6%)

Query: 252  MSYDLLPI-ENDVYKYETSGIGEARVKEVLLDEDDDLWIALRHKHIAEVSQEVTRSLKDF 310
            +  D+LP+ E +    E SG+ +A  K  LL+ED   W A     +++     T   +  
Sbjct: 1300 LELDILPLQEANAELSEKSGMLQAEKK--LLEEDVKRWKARNQHLVSQQKDPDTEEYRKL 1357

Query: 311  SSSKRMNTGEKTTMRDLSQMLKKMPQYQKELSKYSTHLHLAEDCMKHYQGTVDKLCRVEQ 370
             S K ++T      + + Q+ +++ + + E+++ +  L   ++ ++  +  ++K+   ++
Sbjct: 1358 LSEKEVHT------KRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKE 1411

Query: 371  DLAMGTDAEGEKIKDPMRAIVPI 393
             +    DA+   I++ ++ I  +
Sbjct: 1412 TIQKDLDAKIIDIQEKVKTITQV 1434


>gi|209364550 suppressor of S. cerevisiae gcr2 isoform 3 [Homo
           sapiens]
          Length = 601

 Score = 31.2 bits (69), Expect = 2.9
 Identities = 21/65 (32%), Positives = 32/65 (49%), Gaps = 7/65 (10%)

Query: 283 EDDDLWIALRHKHIAEVSQEVTRSLKDFSSSKRMNTGEKTTMRDLSQMLKKMPQYQKELS 342
           EDDD W+ L    + ++ QE     +  S SK     EK    DL+++ + M  +   +S
Sbjct: 367 EDDDQWLDLSPDQLDQLLQEAVGKKESESVSKE----EKEQNYDLTEVSESMKAF---IS 419

Query: 343 KYSTH 347
           K STH
Sbjct: 420 KVSTH 424


>gi|209364547 suppressor of S. cerevisiae gcr2 isoform 2 [Homo
           sapiens]
          Length = 677

 Score = 31.2 bits (69), Expect = 2.9
 Identities = 21/65 (32%), Positives = 32/65 (49%), Gaps = 7/65 (10%)

Query: 283 EDDDLWIALRHKHIAEVSQEVTRSLKDFSSSKRMNTGEKTTMRDLSQMLKKMPQYQKELS 342
           EDDD W+ L    + ++ QE     +  S SK     EK    DL+++ + M  +   +S
Sbjct: 443 EDDDQWLDLSPDQLDQLLQEAVGKKESESVSKE----EKEQNYDLTEVSESMKAF---IS 495

Query: 343 KYSTH 347
           K STH
Sbjct: 496 KVSTH 500


>gi|6005784 suppressor of S. cerevisiae gcr2 isoform 1 [Homo
           sapiens]
          Length = 644

 Score = 31.2 bits (69), Expect = 2.9
 Identities = 21/65 (32%), Positives = 32/65 (49%), Gaps = 7/65 (10%)

Query: 283 EDDDLWIALRHKHIAEVSQEVTRSLKDFSSSKRMNTGEKTTMRDLSQMLKKMPQYQKELS 342
           EDDD W+ L    + ++ QE     +  S SK     EK    DL+++ + M  +   +S
Sbjct: 410 EDDDQWLDLSPDQLDQLLQEAVGKKESESVSKE----EKEQNYDLTEVSESMKAF---IS 462

Query: 343 KYSTH 347
           K STH
Sbjct: 463 KVSTH 467


>gi|71565160 SMC1 structural maintenance of chromosomes 1-like 2
           [Homo sapiens]
          Length = 1235

 Score = 30.0 bits (66), Expect = 6.4
 Identities = 53/233 (22%), Positives = 99/233 (42%), Gaps = 39/233 (16%)

Query: 161 KAQMKNPILERLAEQIATLCATLKEYPAVRYRGEYKDNALLAQLIQDK-LDAYKADDPTM 219
           K  MK    E   +QI TL          + R +Y  N L  ++I+ K L A+  +   +
Sbjct: 686 KGLMKTLRKETDLKQIQTLIQ------GTQTRLKYSQNEL--EMIKKKHLVAFYQEQSQL 737

Query: 220 GEGPDKARSQLLILDRGFDPSSPVLHELTFQAMSYDLLPIENDVYKYETSGIGEARVKEV 279
                   SQ ++L  G       + E  FQ     +  +E+D++++    IG   ++E 
Sbjct: 738 QSELLNIESQCIMLSEGIKERQRRIKE--FQEK---IDKVEDDIFQHFCEEIGVENIRE- 791

Query: 280 LLDEDDDLWIALRHKHIAEVSQEVTRSLKDFSSSK-RMNTGEKTTMRDLSQMLKKMPQYQ 338
                        +KH+    QE+ +   +F   K R+N   + +   L + L K+   +
Sbjct: 792 -----------FENKHVKR-QQEIDQKRLEFEKQKTRLNVQLEYSRSHLKKKLNKINTLK 839

Query: 339 KELSKYST---HLHLAED-CMKHYQGTVDKLCRVEQ---DLAMGTDAEGEKIK 384
           + + K S    HL  AE+ C++    TV++L   +Q   D+ +  ++  EK++
Sbjct: 840 ETIQKGSEDIDHLKKAEENCLQ----TVNELMAKQQQLKDIRVTQNSSAEKVQ 888


>gi|31442420 shroom family member 1 [Homo sapiens]
          Length = 847

 Score = 30.0 bits (66), Expect = 6.4
 Identities = 30/115 (26%), Positives = 47/115 (40%), Gaps = 7/115 (6%)

Query: 118 LVKSRAAKVIKTLTEINIAFLPYESQVYSLDSADSFQSFYSPHKAQMKNPILERLA---- 173
           L+ SR A+V + L        P E ++  L   +        H A+ +  + E L     
Sbjct: 718 LLGSRLARVRRALARAASDSDPDEQRLRLLQRQEEDAKELKEHVARRERAVREVLVRALP 777

Query: 174 -EQIATLCATLKEYPAVRYRGEYKDNALLAQLIQDKLDAYKADDPTMGEGPDKAR 227
            E++   CA L    AV  +    D  +  +L+QD+LDA + D       P  AR
Sbjct: 778 VEELRVYCALLAGKAAVLAQQRNLDERI--RLLQDQLDAIRDDLGHHAPSPSPAR 830


>gi|237858619 polyamine modulated factor 1 binding protein 1 isoform
           a [Homo sapiens]
          Length = 1007

 Score = 29.6 bits (65), Expect = 8.3
 Identities = 23/92 (25%), Positives = 44/92 (47%), Gaps = 8/92 (8%)

Query: 275 RVKEVLLDEDDDLWIALRHKHIAEVSQEVT--RSLKDFSSSKRMNTGEKTTMRDLSQMLK 332
           R ++ L D    +  A+   H  + +Q +    S  +F SSK+ +      +R L Q+ K
Sbjct: 35  RQRKTLQDNQLCMEEAMNSSHDKKQAQALAFEESEVEFGSSKQCH------LRQLQQLKK 88

Query: 333 KMPQYQKELSKYSTHLHLAEDCMKHYQGTVDK 364
           K+   Q+EL  ++  L  +   ++ YQ  ++K
Sbjct: 89  KLLVLQQELEFHTEELQTSYYSLRQYQSILEK 120


>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
            transmembrane signal), 1 [Homo sapiens]
          Length = 3259

 Score = 29.6 bits (65), Expect = 8.3
 Identities = 34/138 (24%), Positives = 59/138 (42%), Gaps = 12/138 (8%)

Query: 248  TFQAMSYDLLPIENDVYKYETSGIGEARVKEVLLDEDDDLWIALRHKHIAEVSQEVTRSL 307
            +F A+  +   +  ++   + S I +   +   L E+  L   L H  +    +EV R  
Sbjct: 2589 SFNALQEEKQDLSKEIESLKVS-ISQLTRQVTALQEEGTL--GLYHAQLKVKEEEVHRLS 2645

Query: 308  KDFSSS-KRMNTGEKTTMRDLSQMLKKMPQYQKELSKYSTHLHLAEDCMKHYQGTVDK-- 364
              FSSS KR+   E+  +    +  KK+ + + +L K   HLH     M++   T ++  
Sbjct: 2646 ALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNETETAEERV 2705

Query: 365  ------LCRVEQDLAMGT 376
                  L  +EQ L M T
Sbjct: 2706 AELARDLVEMEQKLLMVT 2723


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.133    0.381 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,790,277
Number of Sequences: 37866
Number of extensions: 925868
Number of successful extensions: 2706
Number of sequences better than 10.0: 29
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 2671
Number of HSP's gapped (non-prelim): 46
length of query: 603
length of database: 18,247,518
effective HSP length: 108
effective length of query: 495
effective length of database: 14,157,990
effective search space: 7008205050
effective search space used: 7008205050
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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