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Search of human proteins with 4507297
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4507297 syntaxin binding protein 1 isoform a [Homo sapiens]
(603 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4507297 syntaxin binding protein 1 isoform a [Homo sapiens] 1201 0.0
gi|73760415 syntaxin binding protein 1 isoform b [Homo sapiens] 1148 0.0
gi|188528689 syntaxin binding protein 2 isoform a [Homo sapiens] 760 0.0
gi|188528901 syntaxin binding protein 2 isoform b [Homo sapiens] 751 0.0
gi|118600975 syntaxin binding protein 3 [Homo sapiens] 586 e-167
gi|18105063 vacuolar protein sorting 45A [Homo sapiens] 115 2e-25
gi|33469966 vesicle transport-related protein isoform a [Homo sa... 80 5e-15
gi|33469978 vesicle transport-related protein isoform b [Homo sa... 64 4e-10
gi|18105056 vacuolar protein sorting 33A [Homo sapiens] 58 3e-08
gi|31542785 sec1 family domain containing 2 [Homo sapiens] 38 0.023
gi|166295179 ELG protein isoform a [Homo sapiens] 37 0.068
gi|239747793 PREDICTED: protein immuno-reactive with anti-PTH po... 36 0.12
gi|239741673 PREDICTED: protein immuno-reactive with anti-PTH po... 36 0.12
gi|4504063 golgin 97 [Homo sapiens] 35 0.20
gi|118918407 spectrin repeat containing, nuclear envelope 2 isof... 35 0.26
gi|118918403 spectrin repeat containing, nuclear envelope 2 isof... 35 0.26
gi|93277096 limbin [Homo sapiens] 34 0.44
gi|56961680 coiled-coil domain containing 147 [Homo sapiens] 34 0.44
gi|56550047 uveal autoantigen with coiled-coil domains and ankyr... 33 0.58
gi|59850762 uveal autoantigen with coiled-coil domains and ankyr... 33 0.58
gi|149363685 hypothetical protein LOC23379 [Homo sapiens] 33 0.99
gi|114155142 nuclear pore complex-associated protein TPR [Homo s... 32 1.3
gi|209364550 suppressor of S. cerevisiae gcr2 isoform 3 [Homo sa... 31 2.9
gi|209364547 suppressor of S. cerevisiae gcr2 isoform 2 [Homo sa... 31 2.9
gi|6005784 suppressor of S. cerevisiae gcr2 isoform 1 [Homo sapi... 31 2.9
gi|71565160 SMC1 structural maintenance of chromosomes 1-like 2 ... 30 6.4
gi|31442420 shroom family member 1 [Homo sapiens] 30 6.4
gi|237858619 polyamine modulated factor 1 binding protein 1 isof... 30 8.3
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 30 8.3
>gi|4507297 syntaxin binding protein 1 isoform a [Homo sapiens]
Length = 603
Score = 1201 bits (3106), Expect = 0.0
Identities = 603/603 (100%), Positives = 603/603 (100%)
Query: 1 MAPIGLKAVVGEKIMHDVIKKVKKKGEWKVLVVDQLSMRMLSSCCKMTDIMTEGITIVED 60
MAPIGLKAVVGEKIMHDVIKKVKKKGEWKVLVVDQLSMRMLSSCCKMTDIMTEGITIVED
Sbjct: 1 MAPIGLKAVVGEKIMHDVIKKVKKKGEWKVLVVDQLSMRMLSSCCKMTDIMTEGITIVED 60
Query: 61 INKRREPLPSLEAVYLITPSEKSVHSLISDFKDPPTAKYRAAHVFFTDSCPDALFNELVK 120
INKRREPLPSLEAVYLITPSEKSVHSLISDFKDPPTAKYRAAHVFFTDSCPDALFNELVK
Sbjct: 61 INKRREPLPSLEAVYLITPSEKSVHSLISDFKDPPTAKYRAAHVFFTDSCPDALFNELVK 120
Query: 121 SRAAKVIKTLTEINIAFLPYESQVYSLDSADSFQSFYSPHKAQMKNPILERLAEQIATLC 180
SRAAKVIKTLTEINIAFLPYESQVYSLDSADSFQSFYSPHKAQMKNPILERLAEQIATLC
Sbjct: 121 SRAAKVIKTLTEINIAFLPYESQVYSLDSADSFQSFYSPHKAQMKNPILERLAEQIATLC 180
Query: 181 ATLKEYPAVRYRGEYKDNALLAQLIQDKLDAYKADDPTMGEGPDKARSQLLILDRGFDPS 240
ATLKEYPAVRYRGEYKDNALLAQLIQDKLDAYKADDPTMGEGPDKARSQLLILDRGFDPS
Sbjct: 181 ATLKEYPAVRYRGEYKDNALLAQLIQDKLDAYKADDPTMGEGPDKARSQLLILDRGFDPS 240
Query: 241 SPVLHELTFQAMSYDLLPIENDVYKYETSGIGEARVKEVLLDEDDDLWIALRHKHIAEVS 300
SPVLHELTFQAMSYDLLPIENDVYKYETSGIGEARVKEVLLDEDDDLWIALRHKHIAEVS
Sbjct: 241 SPVLHELTFQAMSYDLLPIENDVYKYETSGIGEARVKEVLLDEDDDLWIALRHKHIAEVS 300
Query: 301 QEVTRSLKDFSSSKRMNTGEKTTMRDLSQMLKKMPQYQKELSKYSTHLHLAEDCMKHYQG 360
QEVTRSLKDFSSSKRMNTGEKTTMRDLSQMLKKMPQYQKELSKYSTHLHLAEDCMKHYQG
Sbjct: 301 QEVTRSLKDFSSSKRMNTGEKTTMRDLSQMLKKMPQYQKELSKYSTHLHLAEDCMKHYQG 360
Query: 361 TVDKLCRVEQDLAMGTDAEGEKIKDPMRAIVPILLDANVSTYDKIRIILLYIFLKNGITE 420
TVDKLCRVEQDLAMGTDAEGEKIKDPMRAIVPILLDANVSTYDKIRIILLYIFLKNGITE
Sbjct: 361 TVDKLCRVEQDLAMGTDAEGEKIKDPMRAIVPILLDANVSTYDKIRIILLYIFLKNGITE 420
Query: 421 ENLNKLIQHAQIPPEDSEIITNMAHLGVPIVTDSTLRRRSKPERKERISEQTYQLSRWTP 480
ENLNKLIQHAQIPPEDSEIITNMAHLGVPIVTDSTLRRRSKPERKERISEQTYQLSRWTP
Sbjct: 421 ENLNKLIQHAQIPPEDSEIITNMAHLGVPIVTDSTLRRRSKPERKERISEQTYQLSRWTP 480
Query: 481 IIKDIMEDTIEDKLDTKHYPYISTRSSASFSTTAVSARYGHWHKNKAPGEYRSGPRLIIF 540
IIKDIMEDTIEDKLDTKHYPYISTRSSASFSTTAVSARYGHWHKNKAPGEYRSGPRLIIF
Sbjct: 481 IIKDIMEDTIEDKLDTKHYPYISTRSSASFSTTAVSARYGHWHKNKAPGEYRSGPRLIIF 540
Query: 541 ILGGVSLNEMRCAYEVTQANGKWEVLIGSTHILTPTKFLMDLRHPDFRESSRVSFEDQAP 600
ILGGVSLNEMRCAYEVTQANGKWEVLIGSTHILTPTKFLMDLRHPDFRESSRVSFEDQAP
Sbjct: 541 ILGGVSLNEMRCAYEVTQANGKWEVLIGSTHILTPTKFLMDLRHPDFRESSRVSFEDQAP 600
Query: 601 TME 603
TME
Sbjct: 601 TME 603
>gi|73760415 syntaxin binding protein 1 isoform b [Homo sapiens]
Length = 594
Score = 1148 bits (2970), Expect = 0.0
Identities = 578/583 (99%), Positives = 579/583 (99%)
Query: 1 MAPIGLKAVVGEKIMHDVIKKVKKKGEWKVLVVDQLSMRMLSSCCKMTDIMTEGITIVED 60
MAPIGLKAVVGEKIMHDVIKKVKKKGEWKVLVVDQLSMRMLSSCCKMTDIMTEGITIVED
Sbjct: 1 MAPIGLKAVVGEKIMHDVIKKVKKKGEWKVLVVDQLSMRMLSSCCKMTDIMTEGITIVED 60
Query: 61 INKRREPLPSLEAVYLITPSEKSVHSLISDFKDPPTAKYRAAHVFFTDSCPDALFNELVK 120
INKRREPLPSLEAVYLITPSEKSVHSLISDFKDPPTAKYRAAHVFFTDSCPDALFNELVK
Sbjct: 61 INKRREPLPSLEAVYLITPSEKSVHSLISDFKDPPTAKYRAAHVFFTDSCPDALFNELVK 120
Query: 121 SRAAKVIKTLTEINIAFLPYESQVYSLDSADSFQSFYSPHKAQMKNPILERLAEQIATLC 180
SRAAKVIKTLTEINIAFLPYESQVYSLDSADSFQSFYSPHKAQMKNPILERLAEQIATLC
Sbjct: 121 SRAAKVIKTLTEINIAFLPYESQVYSLDSADSFQSFYSPHKAQMKNPILERLAEQIATLC 180
Query: 181 ATLKEYPAVRYRGEYKDNALLAQLIQDKLDAYKADDPTMGEGPDKARSQLLILDRGFDPS 240
ATLKEYPAVRYRGEYKDNALLAQLIQDKLDAYKADDPTMGEGPDKARSQLLILDRGFDPS
Sbjct: 181 ATLKEYPAVRYRGEYKDNALLAQLIQDKLDAYKADDPTMGEGPDKARSQLLILDRGFDPS 240
Query: 241 SPVLHELTFQAMSYDLLPIENDVYKYETSGIGEARVKEVLLDEDDDLWIALRHKHIAEVS 300
SPVLHELTFQAMSYDLLPIENDVYKYETSGIGEARVKEVLLDEDDDLWIALRHKHIAEVS
Sbjct: 241 SPVLHELTFQAMSYDLLPIENDVYKYETSGIGEARVKEVLLDEDDDLWIALRHKHIAEVS 300
Query: 301 QEVTRSLKDFSSSKRMNTGEKTTMRDLSQMLKKMPQYQKELSKYSTHLHLAEDCMKHYQG 360
QEVTRSLKDFSSSKRMNTGEKTTMRDLSQMLKKMPQYQKELSKYSTHLHLAEDCMKHYQG
Sbjct: 301 QEVTRSLKDFSSSKRMNTGEKTTMRDLSQMLKKMPQYQKELSKYSTHLHLAEDCMKHYQG 360
Query: 361 TVDKLCRVEQDLAMGTDAEGEKIKDPMRAIVPILLDANVSTYDKIRIILLYIFLKNGITE 420
TVDKLCRVEQDLAMGTDAEGEKIKDPMRAIVPILLDANVSTYDKIRIILLYIFLKNGITE
Sbjct: 361 TVDKLCRVEQDLAMGTDAEGEKIKDPMRAIVPILLDANVSTYDKIRIILLYIFLKNGITE 420
Query: 421 ENLNKLIQHAQIPPEDSEIITNMAHLGVPIVTDSTLRRRSKPERKERISEQTYQLSRWTP 480
ENLNKLIQHAQIPPEDSEIITNMAHLGVPIVTDSTLRRRSKPERKERISEQTYQLSRWTP
Sbjct: 421 ENLNKLIQHAQIPPEDSEIITNMAHLGVPIVTDSTLRRRSKPERKERISEQTYQLSRWTP 480
Query: 481 IIKDIMEDTIEDKLDTKHYPYISTRSSASFSTTAVSARYGHWHKNKAPGEYRSGPRLIIF 540
IIKDIMEDTIEDKLDTKHYPYISTRSSASFSTTAVSARYGHWHKNKAPGEYRSGPRLIIF
Sbjct: 481 IIKDIMEDTIEDKLDTKHYPYISTRSSASFSTTAVSARYGHWHKNKAPGEYRSGPRLIIF 540
Query: 541 ILGGVSLNEMRCAYEVTQANGKWEVLIGSTHILTPTKFLMDLR 583
ILGGVSLNEMRCAYEVTQANGKWEVLIGSTHILTP K L L+
Sbjct: 541 ILGGVSLNEMRCAYEVTQANGKWEVLIGSTHILTPQKLLDTLK 583
>gi|188528689 syntaxin binding protein 2 isoform a [Homo sapiens]
Length = 593
Score = 760 bits (1962), Expect = 0.0
Identities = 375/587 (63%), Positives = 474/587 (80%), Gaps = 4/587 (0%)
Query: 1 MAPIGLKAVVGEKIMHDVIKKVKKKGEWKVLVVDQLSMRMLSSCCKMTDIMTEGITIVED 60
MAP GLKAVVGEKI+ VI+ VKK GEWKVL++D SMR+LSSCCKM+DI+ EGITIVED
Sbjct: 1 MAPSGLKAVVGEKILSGVIRSVKKDGEWKVLIMDHPSMRILSSCCKMSDILAEGITIVED 60
Query: 61 INKRREPLPSLEAVYLITPSEKSVHSLISDFKDPPTAKYRAAHVFFTDSCPDALFNELVK 120
INKRREP+PSLEA+YL++P+EKSV +LI DF+ PT Y+AAH+FFTD+CP+ LF+EL +
Sbjct: 61 INKRREPIPSLEAIYLLSPTEKSVQALIKDFQGTPTFTYKAAHIFFTDTCPEPLFSELGR 120
Query: 121 SRAAKVIKTLTEINIAFLPYESQVYSLDSADSFQSFYSPHKAQMKNPILERLAEQIATLC 180
SR AKV+KTL EI++AFLPYE+QV+SLD+ S + Y P +A+ + LE LA+QIATLC
Sbjct: 121 SRLAKVVKTLKEIHLAFLPYEAQVFSLDAPHSTYNLYCPFRAEERTRQLEVLAQQIATLC 180
Query: 181 ATLKEYPAVRYRGEYKDNALLAQLIQDKLDAYKADDPTMGEGPDKARSQLLILDRGFDPS 240
ATL+EYPA+RYR +D A LA + KL+A+KAD P++GEGP+K RSQLLI+DR DP
Sbjct: 181 ATLQEYPAIRYRKGPEDTAQLAHAVLAKLNAFKADTPSLGEGPEKTRSQLLIMDRAADPV 240
Query: 241 SPVLHELTFQAMSYDLLPIENDVYKYETSGIGEARVKEVLLDEDDDLWIALRHKHIAEVS 300
SP+LHELTFQAM+YDLL IE D Y+YET+G+ EAR K VLLDEDDDLW+ LRH HIA+VS
Sbjct: 241 SPLLHELTFQAMAYDLLDIEQDTYRYETTGLSEAREKAVLLDEDDDLWVELRHMHIADVS 300
Query: 301 QEVTRSLKDFSSSKRMNTGEKTTMRDLSQMLKKMPQYQKELSKYSTHLHLAEDCMKHYQG 360
++VT L+ F SKR+ T +K ++DLSQ+LKKMPQYQKEL+KYSTHLHLA+DCMKH++G
Sbjct: 301 KKVTELLRTFCESKRLTT-DKANIKDLSQILKKMPQYQKELNKYSTHLHLADDCMKHFKG 359
Query: 361 TVDKLCRVEQDLAMGTDAEGEKIKDPMRAIVPILLDANVSTYDKIRIILLYIFLKNGITE 420
+V+KLC VEQDLAMG+DAEGEKIKD M+ IVP+LLDA V YDKIR++LLYI L+NG++E
Sbjct: 360 SVEKLCSVEQDLAMGSDAEGEKIKDSMKLIVPVLLDAAVPAYDKIRVLLLYILLRNGVSE 419
Query: 421 ENLNKLIQHAQIPPEDSEIITNMAHLGVPIVTDSTLRRRSKPERKERISEQTYQLSRWTP 480
ENL KLIQHA + S +I N+ LG + S+ E +ER+ E TYQLSRWTP
Sbjct: 420 ENLAKLIQHANVQAH-SSLIRNLEQLGGTVTNPGGSGTSSRLEPRERM-EPTYQLSRWTP 477
Query: 481 IIKDIMEDTIEDKLDTKHYPYISTRSSASFSTTAVSARYGHWHKNKAPGEYRSGPRLIIF 540
+IKD+MED +ED+LD +P++S + + S AVSAR+GHWHKNKA E R+GPRLI++
Sbjct: 478 VIKDVMEDAVEDRLDRNLWPFVSDPAPTASSQAAVSARFGHWHKNKAGIEARAGPRLIVY 537
Query: 541 ILGGVSLNEMRCAYEVTQA-NGKWEVLIGSTHILTPTKFLMDLRHPD 586
++GGV+++EMR AYEVT+A GKWEVLIGS+HILTPT+FL DL+ D
Sbjct: 538 VMGGVAMSEMRAAYEVTRATEGKWEVLIGSSHILTPTRFLDDLKALD 584
>gi|188528901 syntaxin binding protein 2 isoform b [Homo sapiens]
Length = 590
Score = 751 bits (1940), Expect = 0.0
Identities = 373/587 (63%), Positives = 472/587 (80%), Gaps = 7/587 (1%)
Query: 1 MAPIGLKAVVGEKIMHDVIKKVKKKGEWKVLVVDQLSMRMLSSCCKMTDIMTEGITIVED 60
MAP GLKAVVGEKI+ VI+ VKK GEWKVL++D SMR+LSSCCKM+DI+ EGITIVED
Sbjct: 1 MAPSGLKAVVGEKILSGVIRSVKKDGEWKVLIMDHPSMRILSSCCKMSDILAEGITIVED 60
Query: 61 INKRREPLPSLEAVYLITPSEKSVHSLISDFKDPPTAKYRAAHVFFTDSCPDALFNELVK 120
INKRREP+PSLEA+YL++P+EK+ LI DF+ PT Y+AAH+FFTD+CP+ LF+EL +
Sbjct: 61 INKRREPIPSLEAIYLLSPTEKA---LIKDFQGTPTFTYKAAHIFFTDTCPEPLFSELGR 117
Query: 121 SRAAKVIKTLTEINIAFLPYESQVYSLDSADSFQSFYSPHKAQMKNPILERLAEQIATLC 180
SR AKV+KTL EI++AFLPYE+QV+SLD+ S + Y P +A+ + LE LA+QIATLC
Sbjct: 118 SRLAKVVKTLKEIHLAFLPYEAQVFSLDAPHSTYNLYCPFRAEERTRQLEVLAQQIATLC 177
Query: 181 ATLKEYPAVRYRGEYKDNALLAQLIQDKLDAYKADDPTMGEGPDKARSQLLILDRGFDPS 240
ATL+EYPA+RYR +D A LA + KL+A+KAD P++GEGP+K RSQLLI+DR DP
Sbjct: 178 ATLQEYPAIRYRKGPEDTAQLAHAVLAKLNAFKADTPSLGEGPEKTRSQLLIMDRAADPV 237
Query: 241 SPVLHELTFQAMSYDLLPIENDVYKYETSGIGEARVKEVLLDEDDDLWIALRHKHIAEVS 300
SP+LHELTFQAM+YDLL IE D Y+YET+G+ EAR K VLLDEDDDLW+ LRH HIA+VS
Sbjct: 238 SPLLHELTFQAMAYDLLDIEQDTYRYETTGLSEAREKAVLLDEDDDLWVELRHMHIADVS 297
Query: 301 QEVTRSLKDFSSSKRMNTGEKTTMRDLSQMLKKMPQYQKELSKYSTHLHLAEDCMKHYQG 360
++VT L+ F SKR+ T +K ++DLSQ+LKKMPQYQKEL+KYSTHLHLA+DCMKH++G
Sbjct: 298 KKVTELLRTFCESKRLTT-DKANIKDLSQILKKMPQYQKELNKYSTHLHLADDCMKHFKG 356
Query: 361 TVDKLCRVEQDLAMGTDAEGEKIKDPMRAIVPILLDANVSTYDKIRIILLYIFLKNGITE 420
+V+KLC VEQDLAMG+DAEGEKIKD M+ IVP+LLDA V YDKIR++LLYI L+NG++E
Sbjct: 357 SVEKLCSVEQDLAMGSDAEGEKIKDSMKLIVPVLLDAAVPAYDKIRVLLLYILLRNGVSE 416
Query: 421 ENLNKLIQHAQIPPEDSEIITNMAHLGVPIVTDSTLRRRSKPERKERISEQTYQLSRWTP 480
ENL KLIQHA + S +I N+ LG + S+ E +ER+ E TYQLSRWTP
Sbjct: 417 ENLAKLIQHANVQAH-SSLIRNLEQLGGTVTNPGGSGTSSRLEPRERM-EPTYQLSRWTP 474
Query: 481 IIKDIMEDTIEDKLDTKHYPYISTRSSASFSTTAVSARYGHWHKNKAPGEYRSGPRLIIF 540
+IKD+MED +ED+LD +P++S + + S AVSAR+GHWHKNKA E R+GPRLI++
Sbjct: 475 VIKDVMEDAVEDRLDRNLWPFVSDPAPTASSQAAVSARFGHWHKNKAGIEARAGPRLIVY 534
Query: 541 ILGGVSLNEMRCAYEVTQA-NGKWEVLIGSTHILTPTKFLMDLRHPD 586
++GGV+++EMR AYEVT+A GKWEVLIGS+HILTPT+FL DL+ D
Sbjct: 535 VMGGVAMSEMRAAYEVTRATEGKWEVLIGSSHILTPTRFLDDLKALD 581
>gi|118600975 syntaxin binding protein 3 [Homo sapiens]
Length = 592
Score = 586 bits (1511), Expect = e-167
Identities = 303/589 (51%), Positives = 433/589 (73%), Gaps = 22/589 (3%)
Query: 1 MAPIGLKAVVGEKIMHDVIKKVKKKGEWKVLVVDQLSMRMLSSCCKMTDIMTEGITIVED 60
+A GLK+VV +KI V KK+GEWK++++D+ + ++L+SCCKMTD++ EGIT+VE+
Sbjct: 5 VAERGLKSVVWQKIKATVFDDCKKEGEWKIMLLDEFTTKLLASCCKMTDLLEEGITVVEN 64
Query: 61 INKRREPLPSLEAVYLITPSEKSVHSLISDFKDPPTAKYRAAHVFFTDSCPDALFNELVK 120
I K REP+ ++A+Y ITP+ KSV + DF KY+AA+++FTD CPD LFN+ +K
Sbjct: 65 IYKNREPVRQMKALYFITPTSKSVDCFLHDFASKSENKYKAAYIYFTDFCPDNLFNK-IK 123
Query: 121 SRAAKVIKTLTEINIAFLPYESQVYSLDSADSFQSFYSPH--KAQMKNPILERLAEQIAT 178
+ +K I+ EINI+F+P+ESQVY+LD D+F YSP A+ K+ I+E +A+QI T
Sbjct: 124 ASCSKSIRRCKEINISFIPHESQVYTLDVPDAFYYCYSPDPGNAKGKDAIMETMADQIVT 183
Query: 179 LCATLKEYPAVRYRGEYKDNAL-LAQLIQDKL-DAYKADDPTMGEGPDKARSQLLILDRG 236
+CATL E P VRY+ + DNA LAQL++ KL D YK D+ ++ +G K SQLLI+DRG
Sbjct: 184 VCATLDENPGVRYKSKPLDNASKLAQLVEKKLEDYYKIDEKSLIKG--KTHSQLLIIDRG 241
Query: 237 FDPSSPVLHELTFQAMSYDLLPIENDVYKYETSGIGEARVKEVLLDEDDDLWIALRHKHI 296
FDP S VLHELTFQAM+YDLLPIEND YKY+T G + KE +L+E+DDLW+ +RH+HI
Sbjct: 242 FDPVSTVLHELTFQAMAYDLLPIENDTYKYKTDG----KEKEAILEEEDDLWVRIRHRHI 297
Query: 297 AEVSQEVTRSLKDFSSSKRMNTGEKTTMRDLSQMLKKMPQYQKELSKYSTHLHLAEDCMK 356
A V +E+ + +K+ SS+K+ G KT++ L+Q++KKMP ++K+++K HL+LAEDCM
Sbjct: 298 AVVLEEIPKLMKEISSTKKATEG-KTSLSALTQLMKKMPHFRKQITKQVVHLNLAEDCMN 356
Query: 357 HYQGTVDKLCRVEQDLAMGTDAEGEKIKDPMRAIVPILLDANVSTYDKIRIILLYIFLKN 416
++ ++KLC+ EQDLA+GTDAEG+K+KD MR ++P+LL+ N DKIR ILLYIF N
Sbjct: 357 KFKLNIEKLCKTEQDLALGTDAEGQKVKDSMRVLLPVLLNKNHDNCDKIRAILLYIFSIN 416
Query: 417 GITEENLNKLIQHAQIPPEDSEIITNMAHLGVPIVTDSTLRRRSKPERKERISEQTYQLS 476
G TEENL++LIQ+ +I E S++I N ++LGVPIV S ++ KP RK+R +E+T+QLS
Sbjct: 417 GTTEENLDRLIQNVKIENE-SDMIRNWSYLGVPIVPQS---QQGKPLRKDRSAEETFQLS 472
Query: 477 RWTPIIKDIMEDTIEDKLDTKHYPYISTRSSASFSTTAVSARYGHWHKNKAP--GEYRSG 534
RWTP IKDIMED I+++LD+K +PY S + + AVSAR K +A + ++G
Sbjct: 473 RWTPFIKDIMEDAIDNRLDSKEWPYCSQCPAVWNGSGAVSAR----QKPRANYLEDRKNG 528
Query: 535 PRLIIFILGGVSLNEMRCAYEVTQANGKWEVLIGSTHILTPTKFLMDLR 583
+LI+F++GG++ +E+RCAYEV+QA+ EV+IGSTH+LTP K L D++
Sbjct: 529 SKLIVFVIGGITYSEVRCAYEVSQAHKSCEVIIGSTHVLTPKKLLDDIK 577
>gi|18105063 vacuolar protein sorting 45A [Homo sapiens]
Length = 570
Score = 115 bits (287), Expect = 2e-25
Identities = 119/587 (20%), Positives = 262/587 (44%), Gaps = 67/587 (11%)
Query: 29 KVLVVDQLSMRMLSSCCKMTDIMTEGITIVEDINKR-REPLPSLEAVYLITPSEKSVHSL 87
KVL++D+ + ++S ++I+ + + + E I+ + RE + L+A+ + P++++V +
Sbjct: 23 KVLLMDKETTGIVSMVYTQSEILQKEVYLFERIDSQNREIMKHLKAICFLRPTKENVDYI 82
Query: 88 ISDFKDPPTAKYRAAHVFFTDSCPDALFNELVKSRAAKVIKTLTEINIAFLPYESQVYSL 147
I + + P KY ++F++ + L ++ +V+ + E ++ ++SL
Sbjct: 83 IQELRRP---KYTIYFIYFSNVISKSDVKSLAEADEQEVVAEVQEFYGDYIAVNPHLFSL 139
Query: 148 DSADSFQSF-YSPHKAQMKNPILERLAEQIATLCATLKEYPAVRYRGEYKDNALLAQLIQ 206
+ Q + P + L R + + L +LK+ P +RY+ + LA+ ++
Sbjct: 140 NILGCCQGRNWDPAQ-------LSRTTQGLTALLLSLKKCPMIRYQLSSEAAKRLAECVK 192
Query: 207 DKLDA-YKADDPTMGEGPDKARSQLLILDRGFDPSSPVLHELTFQAMSYDLLPIEND-VY 264
+ Y+ + E P LLILDR D +P+L++ T+QAM ++LL I N+ +
Sbjct: 193 QVITKEYELFEFRRTEVPPL----LLILDRCDDAITPLLNQWTYQAMVHELLGINNNRID 248
Query: 265 KYETSGIGEARVKEVLLDEDDDLWIALRHKHIAEVSQEVTRSLKDFSSSKRMNTGEKTTM 324
GI + + VL E+D+ + + + AE+ + ++DF K + ++
Sbjct: 249 LSRVPGISKDLREVVLSAENDEFYANNMYLNFAEIGSNIKNLMEDFQKKKPKEQQKLESI 308
Query: 325 RDLSQMLKKMPQYQKELSKYSTHLHLAEDCMKHY-QGTVDKLCRVEQDLAMGTDAEGEKI 383
D+ ++ PQ++K S H+ + + + + + ++ VEQ+LA D
Sbjct: 309 ADMKAFVENYPQFKKMSGTVSKHVTVVGELSRLVSERNLLEVSEVEQELACQNDH----- 363
Query: 384 KDPMRAIVPILLDANVSTYDKIRIILLYIFLKNGITEENLNKL---IQHAQIPPEDSEII 440
++ I +L + V+ +D R+++LY + +L L +++ + + +++
Sbjct: 364 SSALQNIKRLLQNPKVTEFDAARLVMLYALHYERHSSNSLPGLMMDLRNKGVSEKYRKLV 423
Query: 441 TNMAHLGVPIVTDSTLRRRSKPERKERISEQTYQ--------LSRWTPIIKDIMEDTIED 492
+ + G V S L P+ I++Q + ++ P + + ++ I+
Sbjct: 424 SAVVEYGGKRVRGSDL---FSPKDAVAITKQFLKGLKGVENVYTQHQPFLHETLDHLIKG 480
Query: 493 KLDTKHYPYISTRSSASFSTTAVSARYGHWHKNKAPGEYRSGPR-LIIFILGGVSLNEMR 551
+L YPY+ P R P+ +I+F++GG + E
Sbjct: 481 RLKENLYPYL------------------------GPSTLRDRPQDIIVFVIGGATYEEAL 516
Query: 552 CAYEVTQANGKWEVLIGSTHILTPTKFLMDL----RHPDFRESSRVS 594
Y + + +++G T + FL ++ H +ESS+V+
Sbjct: 517 TVYNLNRTTPGVRIVLGGTTVHNTKSFLEEVLASGLHSRSKESSQVT 563
>gi|33469966 vesicle transport-related protein isoform a [Homo
sapiens]
Length = 642
Score = 80.1 bits (196), Expect = 5e-15
Identities = 89/455 (19%), Positives = 194/455 (42%), Gaps = 62/455 (13%)
Query: 4 IGLKAVVGEKIMHDVIKKVKKKGEWKVLVVDQLSMRMLSSCCKMTDIMTEGITIVEDINK 63
+ LK ++ + H IK + WKVL+ D+ ++S + ++ GIT+ ++
Sbjct: 21 VALKRMLNFNVPH--IKNSTGEPVWKVLIYDRFGQDIISPLLSVKELRDMGITLHLLLHS 78
Query: 64 RREPLPSLEAVYLITPSEKSVHSLISDFKDPPTAKYRAAHV-FFTDSCPDALFNELVKSR 122
R+P+P + AVY + P+E+++ + D ++ Y + + S + + N + +
Sbjct: 79 DRDPIPDVPAVYFVMPTEENIDRMCQDLRNQLYESYYLNFISAISRSKLEDIANAALAAS 138
Query: 123 AAKVIKTLTEINIAFLPYESQVYSLDSAD----SFQSFYSPHKAQMK-NPILERLAEQIA 177
A + + + + F+ E ++ L + + S+++ P + +++ + + +
Sbjct: 139 AVTQVAKVFDQYLNFITLEDDMFVLCNQNKELVSYRAINRPDITDTEMETVMDTIVDSLF 198
Query: 178 TLCATLKEYPAVRYRGEYKDNALLAQLIQDKLDAYKADD-----------PTMGEGPDKA 226
TL P +R A+++ KLD ++ T+G G
Sbjct: 199 CFFVTLGAVPIIRC-----SRGTAAEMVAVKLDKKLRENLRDARNSLFTGDTLGAGQFSF 253
Query: 227 RSQLLIL-DRGFDPSSPVLHELTFQAMSYDLLPIE-NDVYKYETSGIGEA---------R 275
+ LL+L DR D ++P+ H T+QA+ +D+L N V E+SG+ +
Sbjct: 254 QRPLLVLVDRNIDLATPLHHTWTYQALVHDVLDFHLNRVNLEESSGVENSPAGARPKRKN 313
Query: 276 VKEVLLDEDDDLWIALRHKHIAEVSQEVTRSLKDFSSS----KRMNT---------GEKT 322
K L D W + EV++ V + L+ + + KR+ + G +
Sbjct: 314 KKSYDLTPVDKFWQKHKGSPFPEVAESVQQELESYRAQEDEVKRLKSIMGLEGEDEGAIS 373
Query: 323 TMRD----LSQMLKKMPQYQKELSKYSTHLHLAEDCMKHYQG-TVDKLCRVEQDLAMGTD 377
+ D L+ + +P+ ++ H ++A ++H + +D E+ + T
Sbjct: 374 MLSDNTAKLTSAVSSLPELLEKKRLIDLHTNVATAVLEHIKARKLDVYFEYEEKIMSKTT 433
Query: 378 AEGEKIKDPMRAIVPILLDANVST-YDKIRIILLY 411
+ ++++ I+ D + T DK+R+ L+Y
Sbjct: 434 LD--------KSLLDIISDPDAGTPEDKMRLFLIY 460
>gi|33469978 vesicle transport-related protein isoform b [Homo
sapiens]
Length = 575
Score = 63.9 bits (154), Expect = 4e-10
Identities = 78/405 (19%), Positives = 171/405 (42%), Gaps = 60/405 (14%)
Query: 54 GITIVEDINKRREPLPSLEAVYLITPSEKSVHSLISDFKDPPTAKYRAAHV-FFTDSCPD 112
GIT+ ++ R+P+P + AVY + P+E+++ + D ++ Y + + S +
Sbjct: 2 GITLHLLLHSDRDPIPDVPAVYFVMPTEENIDRMCQDLRNQLYESYYLNFISAISRSKLE 61
Query: 113 ALFNELVKSRAAKVIKTLTEINIAFLPYESQVYSLDSAD----SFQSFYSPHKAQMK-NP 167
+ N + + A + + + + F+ E ++ L + + S+++ P +
Sbjct: 62 DIANAALAASAVTQVAKVFDQYLNFITLEDDMFVLCNQNKELVSYRAINRPDITDTEMET 121
Query: 168 ILERLAEQIATLCATLKEYPAVRYRGEYKDNALLAQLIQDKLDAYKADD----------- 216
+++ + + + TL P +R A+++ KLD ++
Sbjct: 122 VMDTIVDSLFCFFVTLGAVPIIRC-----SRGTAAEMVAVKLDKKLRENLRDARNSLFTG 176
Query: 217 PTMGEGPDKARSQLLIL-DRGFDPSSPVLHELTFQAMSYDLLPIE-NDVYKYETSGIGEA 274
T+G G + LL+L DR D ++P+ H T+QA+ +D+L N V E+SG+ +
Sbjct: 177 DTLGAGQFSFQRPLLVLVDRNIDLATPLHHTWTYQALVHDVLDFHLNRVNLEESSGVENS 236
Query: 275 ---------RVKEVLLDEDDDLWIALRHKHIAEVSQEVTRSLKDFSSS----KRMNT--- 318
K L D W + EV++ V + L+ + + KR+ +
Sbjct: 237 PAGARPKRKNKKSYDLTPVDKFWQKHKGSPFPEVAESVQQELESYRAQEDEVKRLKSIMG 296
Query: 319 ------GEKTTMRD----LSQMLKKMPQYQKELSKYSTHLHLAEDCMKHYQG-TVDKLCR 367
G + + D L+ + +P+ ++ H ++A ++H + +D
Sbjct: 297 LEGEDEGAISMLSDNTAKLTSAVSSLPELLEKKRLIDLHTNVATAVLEHIKARKLDVYFE 356
Query: 368 VEQDLAMGTDAEGEKIKDPMRAIVPILLDANVST-YDKIRIILLY 411
E+ + T + ++++ I+ D + T DK+R+ L+Y
Sbjct: 357 YEEKIMSKTTLD--------KSLLDIISDPDAGTPEDKMRLFLIY 393
>gi|18105056 vacuolar protein sorting 33A [Homo sapiens]
Length = 596
Score = 57.8 bits (138), Expect = 3e-08
Identities = 96/490 (19%), Positives = 192/490 (39%), Gaps = 66/490 (13%)
Query: 132 EINIAFLPYESQVYSLDSADSFQSFYSPHKAQMKNPILERLAEQIATLCATLKEYPAVRY 191
E ++ +P++ + S++S +F+ Y + L A+ + TL A P +
Sbjct: 139 EYSLDLIPFDGDLLSMESEGAFKECY----LEGDQTSLYHAAKGLMTLQALYGTIPQIFG 194
Query: 192 RGEYKDNALLAQLIQDKLDAYKADDPTMGEGPDKARSQLLILDRGFDPSSPVLHELTFQA 251
+GE A+ + + + K + LL+LDR D +P+ +LT++
Sbjct: 195 KGE------CARQVANMMIRMKREFTGSQNSIFPVFDNLLLLDRNVDLLTPLATQLTYEG 248
Query: 252 MSYDLLPIENDVYKY-------ETSGIG----EARVKEVLLDEDDDLWIALRHKHIAEVS 300
+ ++ I+N K + G G K++ L+ ++L+ +R K+ V
Sbjct: 249 LIDEIYGIQNSYVKLPPEKFAPKKQGDGGKDLPTEAKKLQLNSAEELYAEIRDKNFNAVG 308
Query: 301 QEVTRSLKDFSSSKRMNTGEKTTMRDLSQMLKKMPQYQKELSKYSTHLHLAE--DCMKHY 358
+++ K S++ K T+ ++ Q + ++P Q + H +AE +
Sbjct: 309 SVLSKKAKIISAAFEERHNAK-TVGEIKQFVSQLPHMQAARGSLANHTSIAELIKDVTTS 367
Query: 359 QGTVDKLCRVEQDLAMGTDAEGEKIKDPMRAIVPILLDANVSTYDKIRIILLYIFLKNGI 418
+ DKL VEQ+ G D D + + + S +R++ L +G+
Sbjct: 368 EDFFDKL-TVEQEFMSGIDT------DKVNNYIEDCIAQKHSLIKVLRLVCLQSVCNSGL 420
Query: 419 TEENLNKLIQHAQIPPEDSEIIT--NMAHLGV-----------PIVTDSTLRRRSKPERK 465
++ L+ + I+T N+ G+ P + TLR +
Sbjct: 421 KQKVLDYYKREILQTYGYEHILTLHNLEKAGLLKPQTGGRNNYPTIR-KTLRLWMDDVNE 479
Query: 466 ERISEQTYQLSRWTPIIKDIME-------DTIEDKLDTKHYPYISTRSSASFSTTAVSAR 518
+ ++ +Y S + P+ + + +IE+ L P+ R
Sbjct: 480 QNPTDISYVYSGYAPLSVRLAQLLSRPGWRSIEEVLRILPGPHFEERQPLPTGL------ 533
Query: 519 YGHWHKNKAPGEYRSGPRLIIFILGGVSLNEMRCAYEVTQ-ANGKWEVLIGSTHILTPTK 577
K + PGE R +IF LGGV+ E+ ++Q +G E +I +T ++ T
Sbjct: 534 ----QKKRQPGENRV---TLIFFLGGVTFAEIAALRFLSQLEDGGTEYVIATTKLMNGTS 586
Query: 578 FLMDLRHPDF 587
++ L F
Sbjct: 587 WIEALMEKPF 596
>gi|31542785 sec1 family domain containing 2 [Homo sapiens]
Length = 684
Score = 38.1 bits (87), Expect = 0.023
Identities = 82/357 (22%), Positives = 147/357 (41%), Gaps = 75/357 (21%)
Query: 287 LWIALRHKHIAEVSQEVTRSLKDFSSSK----RMNTGEKTTMRDLSQMLKKMPQYQKELS 342
LW AL + E EV R L + +S + +M+ G T Q++ + ++ L
Sbjct: 343 LWEALLNTKHKEAVMEVRRHLVEAASRENLPIKMSMGRVTP----GQLMSYIQLFKNNLK 398
Query: 343 KYSTHLHLAE------DCMKHYQGTV-DKLCRVEQDL--AMGTDAEGEKIKDPMRAIVPI 393
H L + +KH Q D E+ L ++G A + + I P+
Sbjct: 399 ALMNHCGLLQLGLATAQTLKHPQTAKWDNFLAFERLLLQSIGESAMSVVLNQLLPMIKPV 458
Query: 394 LLDANVS-TYDKIRIILLYIFLKNGI---------TEENLNKLIQHAQIPPEDSEI---- 439
N + +++ I+L+YI+ G EE + K + AQ+ E+S +
Sbjct: 459 TQRTNEDYSPEELLILLIYIYSVTGELTVDKDLCEAEEKVKKAL--AQVFCEESGLSPLL 516
Query: 440 --IT------NMAHLGVPIVTD---STLR----RRSKPERKERI---SEQTYQLSRWTPI 481
IT N+ I D ++LR RS ++ + + T+Q S + P+
Sbjct: 517 QKITDWDSSINLTFHKSKIAVDELFTSLRDIAGARSLLKQFKSVYVPGNHTHQAS-YKPL 575
Query: 482 IKDIMEDTIE----DKLDTKHYPYISTRSSASFSTTAVSARYGHWHK--NKAPGEYRSGP 535
+K ++E+ D +D +H +S T + + + K P +Y P
Sbjct: 576 LKQVVEEIFHPERPDSVDIEHM--------SSGLTDLLKTGFSMFMKVSRPHPSDY---P 624
Query: 536 RLIIFILGGVSLNEMRCAYE-VTQANGKWEVLIGSTHILTPTK-----FLMDLRHPD 586
LI+F++GGV+++E++ + V +V++ ST +L P F D HPD
Sbjct: 625 LLILFVVGGVTVSEVKMVKDLVASLKPGTQVIVLSTRLLKPLNIPELLFATDRLHPD 681
>gi|166295179 ELG protein isoform a [Homo sapiens]
Length = 620
Score = 36.6 bits (83), Expect = 0.068
Identities = 26/105 (24%), Positives = 49/105 (46%), Gaps = 15/105 (14%)
Query: 49 DIMTEGITIVEDINKRREPLPSLEAVYLITPSEKSVHSLISDFKDPPTAKYRAAHVFFTD 108
++ + + D+ K+ P LE +Y+ E S + S FK+ Y AH+ + D
Sbjct: 103 NLAQRNVALDRDMMKKAIPKVRLETIYICGVDEMSTQDVFSYFKE-----YPPAHIEWLD 157
Query: 109 --SCPDALFNELVKSRAAKVIKTLTEINIAFLPYESQVYSLDSAD 151
SC +E+ +RA IN++ LP + ++ S D+++
Sbjct: 158 DTSCNVVWLDEMTATRAL--------INMSSLPAQDKIRSRDASE 194
>gi|239747793 PREDICTED: protein immuno-reactive with anti-PTH
polyclonal antibodies [Homo sapiens]
Length = 868
Score = 35.8 bits (81), Expect = 0.12
Identities = 33/147 (22%), Positives = 59/147 (40%), Gaps = 17/147 (11%)
Query: 238 DPSSPVLHELTFQAMSYDLLPIENDVYKYETSGIGEARVKEVLLDEDDDLWIALRHKHIA 297
D +LHE L +E D K + + E++ + +DL AL+
Sbjct: 455 DEKEDLLHENRLMQDEIARLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALKRNE-- 512
Query: 298 EVSQEVTRSLKDFSSSKRMNTGEKTTMRD-LSQMLKKMPQYQKELSKYSTHLHLA----- 351
+ + ++ +S T E TT+R L + + + + E+ Y L+ A
Sbjct: 513 ---ETLAETIACYSGQLAALTDENTTLRSKLEKQRESGQRLETEMQSYRCRLNAALCDHD 569
Query: 352 ------EDCMKHYQGTVDKLCRVEQDL 372
D +QGTVDK C ++++L
Sbjct: 570 QSHSSKRDQELAFQGTVDKCCHLQENL 596
>gi|239741673 PREDICTED: protein immuno-reactive with anti-PTH
polyclonal antibodies [Homo sapiens]
Length = 1430
Score = 35.8 bits (81), Expect = 0.12
Identities = 33/147 (22%), Positives = 59/147 (40%), Gaps = 17/147 (11%)
Query: 238 DPSSPVLHELTFQAMSYDLLPIENDVYKYETSGIGEARVKEVLLDEDDDLWIALRHKHIA 297
D +LHE L +E D K + + E++ + +DL AL+
Sbjct: 1017 DEKEDLLHENRLMQDEIARLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALKRNE-- 1074
Query: 298 EVSQEVTRSLKDFSSSKRMNTGEKTTMRD-LSQMLKKMPQYQKELSKYSTHLHLA----- 351
+ + ++ +S T E TT+R L + + + + E+ Y L+ A
Sbjct: 1075 ---ETLAETIACYSGQLAALTDENTTLRSKLEKQRESGQRLETEMQSYRCRLNAALCDHD 1131
Query: 352 ------EDCMKHYQGTVDKLCRVEQDL 372
D +QGTVDK C ++++L
Sbjct: 1132 QSHSSKRDQELAFQGTVDKCCHLQENL 1158
>gi|4504063 golgin 97 [Homo sapiens]
Length = 767
Score = 35.0 bits (79), Expect = 0.20
Identities = 50/222 (22%), Positives = 103/222 (46%), Gaps = 35/222 (15%)
Query: 148 DSADSFQSFYSPHKAQMKNPILERLAEQIATLCATLKEYPA-VRYRGEYKDNALLA---- 202
DS D F S S + + + +L R EQI L A L +Y VR + K+ +A
Sbjct: 40 DSGDDFASDGSSSREDLSSQLLRR-NEQIRKLEARLSDYAEQVRNLQKIKEKLEIALEKH 98
Query: 203 -----QLIQDKLDAYKADDPTMGEG-------PDKARSQLLI-LDRGFDPSSPVLHELTF 249
+ Q++ + ++A+ M EG D+ S+ + L++ + + L E+
Sbjct: 99 QDSSMRKFQEQNETFQANRAKMAEGLALALARKDQEWSEKMDQLEKEKNILTAQLQEMKN 158
Query: 250 QAMSYDLLPIENDVYKYETSGIGE---ARVKEVLLDEDDDLWIALRHKHIAEVSQEVTRS 306
Q+M+ E D E G + +++K +LL +++ L + + ++E++R+
Sbjct: 159 QSMNLFQRRDEMD----ELEGFQQQELSKIKHMLLKKEESL--GKMEQELEARTRELSRT 212
Query: 307 LKDFSSSKRMNTGEKTTMRDLSQMLKKMPQYQKELSKYSTHL 348
++ +S +M++ DLSQ L+++ ++ L + H+
Sbjct: 213 QEELMNSNQMSS-------DLSQKLEELQRHYSTLEEQRDHV 247
>gi|118918407 spectrin repeat containing, nuclear envelope 2 isoform 5
[Homo sapiens]
Length = 6907
Score = 34.7 bits (78), Expect = 0.26
Identities = 39/163 (23%), Positives = 63/163 (38%), Gaps = 25/163 (15%)
Query: 224 DKARSQLLILDRGFDPSSPVLHELTFQAMSYDLLPIENDVYKYETSGIGEARVKEVLLDE 283
D Q+ I +R +P + VL EL +DL ++N + KY+T G
Sbjct: 1266 DSIAKQIEICNRLEEPGNFVLKELH----PFDLHAMQNIILKYKTQFEGM---------- 1311
Query: 284 DDDLWIALRHKHIAEVSQEVTRSLKDFSSSKRMNTGEKTTMRDLSQMLKKMPQYQKELSK 343
H + S++ ++L+DF +S R + DLS ++ Q K
Sbjct: 1312 ----------NHRVQRSEDTLKALEDFLASLRTAKLSAEPVTDLSASDTQVAQENTLTVK 1361
Query: 344 YST-HLHLAEDCMKHYQGTVDKLCRVEQDLAMGTDAEGEKIKD 385
+HL +D KH + L +D G D E + D
Sbjct: 1362 NKEGEIHLMKDKAKHLDKCLKMLDMSFKDAERGDDTSCENLLD 1404
>gi|118918403 spectrin repeat containing, nuclear envelope 2 isoform 1
[Homo sapiens]
Length = 6885
Score = 34.7 bits (78), Expect = 0.26
Identities = 39/163 (23%), Positives = 63/163 (38%), Gaps = 25/163 (15%)
Query: 224 DKARSQLLILDRGFDPSSPVLHELTFQAMSYDLLPIENDVYKYETSGIGEARVKEVLLDE 283
D Q+ I +R +P + VL EL +DL ++N + KY+T G
Sbjct: 1266 DSIAKQIEICNRLEEPGNFVLKELH----PFDLHAMQNIILKYKTQFEGM---------- 1311
Query: 284 DDDLWIALRHKHIAEVSQEVTRSLKDFSSSKRMNTGEKTTMRDLSQMLKKMPQYQKELSK 343
H + S++ ++L+DF +S R + DLS ++ Q K
Sbjct: 1312 ----------NHRVQRSEDTLKALEDFLASLRTAKLSAEPVTDLSASDTQVAQENTLTVK 1361
Query: 344 YST-HLHLAEDCMKHYQGTVDKLCRVEQDLAMGTDAEGEKIKD 385
+HL +D KH + L +D G D E + D
Sbjct: 1362 NKEGEIHLMKDKAKHLDKCLKMLDMSFKDAERGDDTSCENLLD 1404
>gi|93277096 limbin [Homo sapiens]
Length = 1308
Score = 33.9 bits (76), Expect = 0.44
Identities = 46/233 (19%), Positives = 99/233 (42%), Gaps = 37/233 (15%)
Query: 263 VYKYETSGIGEARVKEVLLDEDDDLWIALRHKHIAEVSQE--------VTRSLKDFSSSK 314
+ K+E +G + E+LL+ +++ K ++ QE +T+ ++
Sbjct: 624 IQKHERAGYLDEDQMEMLLERAQTEVFSIKQKLDNDLKQEKKKLHQKLITKRRRELLQKH 683
Query: 315 RMNTGEKTTMRDLSQMLKKMPQYQKELSKYSTHLHLAEDCMKHYQGTVDKLC-RVEQ--- 370
R E+ ++ + + ++ QY LH M+ + T+++L R++Q
Sbjct: 684 REQRREQASVGEAFRTVEDAGQY----------LHQKRSLMEEHGATLEELQERLDQAAL 733
Query: 371 -DLAMGTDAEGEKIKDPMRAIVPILLDANVSTYDKIRIILLYIFLKNGITEENLNKLIQH 429
DL T + EK D +R L + T + ++ + ++FL+ + E +
Sbjct: 734 DDLRTLTLSLFEKATDELRR-----LQNSAMTQELLKRGVPWLFLQQILEEHGKEMAARA 788
Query: 430 AQIPPEDSEIITNMAHLGVPIVTDSTLRRRSKPERKERISEQTYQLSRWTPII 482
Q+ E+ + GV ++R+R K + E ++E+ +L RW +I
Sbjct: 789 EQLEGEERD----RDQEGV-----QSVRQRLKDDAPEAVTEEQAELRRWEHLI 832
>gi|56961680 coiled-coil domain containing 147 [Homo sapiens]
Length = 872
Score = 33.9 bits (76), Expect = 0.44
Identities = 31/120 (25%), Positives = 52/120 (43%), Gaps = 20/120 (16%)
Query: 253 SYDLLPIENDVYKYETSGIGEARVKEVLLDEDDDLWIALRHKHIAEVSQEVTRSLKDFSS 312
+Y+L+ + + K S E KE+LL E + L++ L+H + E LK +
Sbjct: 723 AYELIQKIHTLQKRLISKTEEVVEKELLLQEKEKLYMELKHVLARQPGPEAAEQLKLY-- 780
Query: 313 SKRMNTGEKTTMRDLSQMLKKMPQYQKELSKYSTHLHLAEDCMKHYQGTVDKLCRVEQDL 372
+ T+ D Q LK + S+ L++ E K Y+ V+KL Q+L
Sbjct: 781 --------RRTLHDKKQQLKVL----------SSELNMYEVQSKEYKYEVEKLTNELQNL 822
>gi|56550047 uveal autoantigen with coiled-coil domains and ankyrin
repeats isoform 2 [Homo sapiens]
Length = 1403
Score = 33.5 bits (75), Expect = 0.58
Identities = 48/244 (19%), Positives = 100/244 (40%), Gaps = 17/244 (6%)
Query: 260 ENDVYKYETSGIG-EARVKEVLLDEDDDLWIALRHKHIAEVSQEVTRSLKDFSS--SKRM 316
END K E + + R K VL+++ ++ AL K + E+ + LKD S ++
Sbjct: 1016 ENDKLKKEIFTLQKDLRDKTVLIEKSHEMERALSRK-----TDELNKQLKDLSQKYTEVK 1070
Query: 317 NTGEKTTMRDLSQMLKKMPQYQKELSKYSTHLHLAEDCMKHYQGTVDKLCRVEQDLAMGT 376
N EK + Q ++ Q L K L E K GT++ L + +
Sbjct: 1071 NVKEKLVEENAKQT-SEILAVQNLLQKQHVPLEQVEALKKSLNGTIENLKEELKSMQRCY 1129
Query: 377 DAEGEKI-------KDPMRAIVPILLDANVSTYDKIRIILLYIFLKNGITEENLNKLIQH 429
+ E + + ++ + VP+ + + + ++ L+ EE+ NK+ +
Sbjct: 1130 EKEQQTVTKLHQLLENQKNSSVPLAEHLQIKEAFEKEVGIIKASLREK-EEESQNKMEEV 1188
Query: 430 AQIPPEDSEIITNMAHLGVPIVTDSTLRRRSKPERKERISEQTYQLSRWTPIIKDIMEDT 489
+++ E + L V D + + +K + + +IS +L+ +++ E+
Sbjct: 1189 SKLQSEVQNTKQALKKLETREVVDLSKYKATKSDLETQISSLNEKLANLNRKYEEVCEEV 1248
Query: 490 IEDK 493
+ K
Sbjct: 1249 LHAK 1252
>gi|59850762 uveal autoantigen with coiled-coil domains and ankyrin
repeats isoform 1 [Homo sapiens]
Length = 1416
Score = 33.5 bits (75), Expect = 0.58
Identities = 48/244 (19%), Positives = 100/244 (40%), Gaps = 17/244 (6%)
Query: 260 ENDVYKYETSGIG-EARVKEVLLDEDDDLWIALRHKHIAEVSQEVTRSLKDFSS--SKRM 316
END K E + + R K VL+++ ++ AL K + E+ + LKD S ++
Sbjct: 1029 ENDKLKKEIFTLQKDLRDKTVLIEKSHEMERALSRK-----TDELNKQLKDLSQKYTEVK 1083
Query: 317 NTGEKTTMRDLSQMLKKMPQYQKELSKYSTHLHLAEDCMKHYQGTVDKLCRVEQDLAMGT 376
N EK + Q ++ Q L K L E K GT++ L + +
Sbjct: 1084 NVKEKLVEENAKQT-SEILAVQNLLQKQHVPLEQVEALKKSLNGTIENLKEELKSMQRCY 1142
Query: 377 DAEGEKI-------KDPMRAIVPILLDANVSTYDKIRIILLYIFLKNGITEENLNKLIQH 429
+ E + + ++ + VP+ + + + ++ L+ EE+ NK+ +
Sbjct: 1143 EKEQQTVTKLHQLLENQKNSSVPLAEHLQIKEAFEKEVGIIKASLREK-EEESQNKMEEV 1201
Query: 430 AQIPPEDSEIITNMAHLGVPIVTDSTLRRRSKPERKERISEQTYQLSRWTPIIKDIMEDT 489
+++ E + L V D + + +K + + +IS +L+ +++ E+
Sbjct: 1202 SKLQSEVQNTKQALKKLETREVVDLSKYKATKSDLETQISSLNEKLANLNRKYEEVCEEV 1261
Query: 490 IEDK 493
+ K
Sbjct: 1262 LHAK 1265
>gi|149363685 hypothetical protein LOC23379 [Homo sapiens]
Length = 2266
Score = 32.7 bits (73), Expect = 0.99
Identities = 23/112 (20%), Positives = 54/112 (48%), Gaps = 3/112 (2%)
Query: 281 LDEDDDLWIALRHKHIA--EVSQEVTRSLKDFSSSKRMNTGEKTTMRDLSQMLKKMPQYQ 338
L+E + I L+ K I + E + + ++R N+ + ++ Q + + + Q
Sbjct: 30 LNEYVEALITLKQKIINTDNLLTEYQKKCDELQFARRENSNLHHQVEEMLQKISPLQKCQ 89
Query: 339 KELSKYSTHLHLAEDCMKHYQGTVDKLCRVEQDLAMGTDAEGEKIKDPMRAI 390
+EL L + +K YQ T + RV+++ + +DA+ +K++ ++ +
Sbjct: 90 EELGSLKAELEEKKSSLKLYQDTHQEYARVKEE-CLKSDAQKKKLEAKVKKL 140
>gi|114155142 nuclear pore complex-associated protein TPR [Homo
sapiens]
Length = 2363
Score = 32.3 bits (72), Expect = 1.3
Identities = 27/143 (18%), Positives = 69/143 (48%), Gaps = 9/143 (6%)
Query: 252 MSYDLLPI-ENDVYKYETSGIGEARVKEVLLDEDDDLWIALRHKHIAEVSQEVTRSLKDF 310
+ D+LP+ E + E SG+ +A K LL+ED W A +++ T +
Sbjct: 1300 LELDILPLQEANAELSEKSGMLQAEKK--LLEEDVKRWKARNQHLVSQQKDPDTEEYRKL 1357
Query: 311 SSSKRMNTGEKTTMRDLSQMLKKMPQYQKELSKYSTHLHLAEDCMKHYQGTVDKLCRVEQ 370
S K ++T + + Q+ +++ + + E+++ + L ++ ++ + ++K+ ++
Sbjct: 1358 LSEKEVHT------KRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKE 1411
Query: 371 DLAMGTDAEGEKIKDPMRAIVPI 393
+ DA+ I++ ++ I +
Sbjct: 1412 TIQKDLDAKIIDIQEKVKTITQV 1434
>gi|209364550 suppressor of S. cerevisiae gcr2 isoform 3 [Homo
sapiens]
Length = 601
Score = 31.2 bits (69), Expect = 2.9
Identities = 21/65 (32%), Positives = 32/65 (49%), Gaps = 7/65 (10%)
Query: 283 EDDDLWIALRHKHIAEVSQEVTRSLKDFSSSKRMNTGEKTTMRDLSQMLKKMPQYQKELS 342
EDDD W+ L + ++ QE + S SK EK DL+++ + M + +S
Sbjct: 367 EDDDQWLDLSPDQLDQLLQEAVGKKESESVSKE----EKEQNYDLTEVSESMKAF---IS 419
Query: 343 KYSTH 347
K STH
Sbjct: 420 KVSTH 424
>gi|209364547 suppressor of S. cerevisiae gcr2 isoform 2 [Homo
sapiens]
Length = 677
Score = 31.2 bits (69), Expect = 2.9
Identities = 21/65 (32%), Positives = 32/65 (49%), Gaps = 7/65 (10%)
Query: 283 EDDDLWIALRHKHIAEVSQEVTRSLKDFSSSKRMNTGEKTTMRDLSQMLKKMPQYQKELS 342
EDDD W+ L + ++ QE + S SK EK DL+++ + M + +S
Sbjct: 443 EDDDQWLDLSPDQLDQLLQEAVGKKESESVSKE----EKEQNYDLTEVSESMKAF---IS 495
Query: 343 KYSTH 347
K STH
Sbjct: 496 KVSTH 500
>gi|6005784 suppressor of S. cerevisiae gcr2 isoform 1 [Homo
sapiens]
Length = 644
Score = 31.2 bits (69), Expect = 2.9
Identities = 21/65 (32%), Positives = 32/65 (49%), Gaps = 7/65 (10%)
Query: 283 EDDDLWIALRHKHIAEVSQEVTRSLKDFSSSKRMNTGEKTTMRDLSQMLKKMPQYQKELS 342
EDDD W+ L + ++ QE + S SK EK DL+++ + M + +S
Sbjct: 410 EDDDQWLDLSPDQLDQLLQEAVGKKESESVSKE----EKEQNYDLTEVSESMKAF---IS 462
Query: 343 KYSTH 347
K STH
Sbjct: 463 KVSTH 467
>gi|71565160 SMC1 structural maintenance of chromosomes 1-like 2
[Homo sapiens]
Length = 1235
Score = 30.0 bits (66), Expect = 6.4
Identities = 53/233 (22%), Positives = 99/233 (42%), Gaps = 39/233 (16%)
Query: 161 KAQMKNPILERLAEQIATLCATLKEYPAVRYRGEYKDNALLAQLIQDK-LDAYKADDPTM 219
K MK E +QI TL + R +Y N L ++I+ K L A+ + +
Sbjct: 686 KGLMKTLRKETDLKQIQTLIQ------GTQTRLKYSQNEL--EMIKKKHLVAFYQEQSQL 737
Query: 220 GEGPDKARSQLLILDRGFDPSSPVLHELTFQAMSYDLLPIENDVYKYETSGIGEARVKEV 279
SQ ++L G + E FQ + +E+D++++ IG ++E
Sbjct: 738 QSELLNIESQCIMLSEGIKERQRRIKE--FQEK---IDKVEDDIFQHFCEEIGVENIRE- 791
Query: 280 LLDEDDDLWIALRHKHIAEVSQEVTRSLKDFSSSK-RMNTGEKTTMRDLSQMLKKMPQYQ 338
+KH+ QE+ + +F K R+N + + L + L K+ +
Sbjct: 792 -----------FENKHVKR-QQEIDQKRLEFEKQKTRLNVQLEYSRSHLKKKLNKINTLK 839
Query: 339 KELSKYST---HLHLAED-CMKHYQGTVDKLCRVEQ---DLAMGTDAEGEKIK 384
+ + K S HL AE+ C++ TV++L +Q D+ + ++ EK++
Sbjct: 840 ETIQKGSEDIDHLKKAEENCLQ----TVNELMAKQQQLKDIRVTQNSSAEKVQ 888
>gi|31442420 shroom family member 1 [Homo sapiens]
Length = 847
Score = 30.0 bits (66), Expect = 6.4
Identities = 30/115 (26%), Positives = 47/115 (40%), Gaps = 7/115 (6%)
Query: 118 LVKSRAAKVIKTLTEINIAFLPYESQVYSLDSADSFQSFYSPHKAQMKNPILERLA---- 173
L+ SR A+V + L P E ++ L + H A+ + + E L
Sbjct: 718 LLGSRLARVRRALARAASDSDPDEQRLRLLQRQEEDAKELKEHVARRERAVREVLVRALP 777
Query: 174 -EQIATLCATLKEYPAVRYRGEYKDNALLAQLIQDKLDAYKADDPTMGEGPDKAR 227
E++ CA L AV + D + +L+QD+LDA + D P AR
Sbjct: 778 VEELRVYCALLAGKAAVLAQQRNLDERI--RLLQDQLDAIRDDLGHHAPSPSPAR 830
>gi|237858619 polyamine modulated factor 1 binding protein 1 isoform
a [Homo sapiens]
Length = 1007
Score = 29.6 bits (65), Expect = 8.3
Identities = 23/92 (25%), Positives = 44/92 (47%), Gaps = 8/92 (8%)
Query: 275 RVKEVLLDEDDDLWIALRHKHIAEVSQEVT--RSLKDFSSSKRMNTGEKTTMRDLSQMLK 332
R ++ L D + A+ H + +Q + S +F SSK+ + +R L Q+ K
Sbjct: 35 RQRKTLQDNQLCMEEAMNSSHDKKQAQALAFEESEVEFGSSKQCH------LRQLQQLKK 88
Query: 333 KMPQYQKELSKYSTHLHLAEDCMKHYQGTVDK 364
K+ Q+EL ++ L + ++ YQ ++K
Sbjct: 89 KLLVLQQELEFHTEELQTSYYSLRQYQSILEK 120
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 29.6 bits (65), Expect = 8.3
Identities = 34/138 (24%), Positives = 59/138 (42%), Gaps = 12/138 (8%)
Query: 248 TFQAMSYDLLPIENDVYKYETSGIGEARVKEVLLDEDDDLWIALRHKHIAEVSQEVTRSL 307
+F A+ + + ++ + S I + + L E+ L L H + +EV R
Sbjct: 2589 SFNALQEEKQDLSKEIESLKVS-ISQLTRQVTALQEEGTL--GLYHAQLKVKEEEVHRLS 2645
Query: 308 KDFSSS-KRMNTGEKTTMRDLSQMLKKMPQYQKELSKYSTHLHLAEDCMKHYQGTVDK-- 364
FSSS KR+ E+ + + KK+ + + +L K HLH M++ T ++
Sbjct: 2646 ALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNETETAEERV 2705
Query: 365 ------LCRVEQDLAMGT 376
L +EQ L M T
Sbjct: 2706 AELARDLVEMEQKLLMVT 2723
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.381
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,790,277
Number of Sequences: 37866
Number of extensions: 925868
Number of successful extensions: 2706
Number of sequences better than 10.0: 29
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 2671
Number of HSP's gapped (non-prelim): 46
length of query: 603
length of database: 18,247,518
effective HSP length: 108
effective length of query: 495
effective length of database: 14,157,990
effective search space: 7008205050
effective search space used: 7008205050
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.