Search of human proteins with 4506987

Search of human proteins with 4506987

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4506987 solute carrier family 18 (vesicular monoamine),
member 1 isoform a [Homo sapiens]
         (525 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|208879454 solute carrier family 18 (vesicular monoamine), mem...  1042   0.0  
gi|4506987 solute carrier family 18 (vesicular monoamine), membe...  1042   0.0  
gi|215272390 solute carrier family 18 (vesicular monoamine), mem...   956   0.0  
gi|215272392 solute carrier family 18 (vesicular monoamine), mem...   877   0.0  
gi|42476325 solute carrier family 18 (vesicular monoamine), memb...   659   0.0  
gi|118582257 vesicular acetylcholine transporter [Homo sapiens]       339   4e-93
gi|16445357 hypothetical protein LOC116843 [Homo sapiens]             106   6e-23
gi|213021148 SVOP-like isoform 1 [Homo sapiens]                        43   8e-04
gi|6912666 sialin [Homo sapiens]                                       41   0.003
gi|24431958 solute carrier family 16, member 7 [Homo sapiens]          41   0.003
gi|115583685 solute carrier family 16, member 1 [Homo sapiens]         40   0.005
gi|109288010 solute carrier family 16, member 3 [Homo sapiens]         38   0.026
gi|109288012 solute carrier family 16, member 3 [Homo sapiens]         38   0.026
gi|4759112 solute carrier family 16, member 3 [Homo sapiens]           38   0.026
gi|4759116 solute carrier family 16, member 5 [Homo sapiens]           38   0.026
gi|225703102 major facilitator superfamily domain containing 10 ...    37   0.034
gi|169217968 PREDICTED: similar to solute carrier family 16, mem...    37   0.034
gi|225703104 major facilitator superfamily domain containing 10 ...    37   0.034
gi|34916028 solute carrier family 16 (monocarboxylic acid transp...    37   0.058
gi|24308167 SV2 related protein [Homo sapiens]                         36   0.099
gi|4507021 solute carrier family 4, anion exchanger, member 1 [H...    35   0.13 
gi|4507001 solute carrier family 22 member 2 [Homo sapiens]            35   0.13 
gi|5730045 solute carrier family 16, member 2 [Homo sapiens]           35   0.13 
gi|21553331 solute carrier family 2 (facilitated glucose transpo...    35   0.17 
gi|156071474 solute carrier family 4, anion exchanger, member 2 ...    35   0.22 
gi|4503847 solute carrier family 37 (glucose-6-phosphate transpo...    33   0.49 
gi|114796626 solute carrier family 16, member 8 [Homo sapiens]         33   0.64 
gi|42542381 solute carrier family 28, member 1 isoform 1 [Homo s...    32   1.1  
gi|24497480 solute carrier family 22 member 6 isoform d [Homo sa...    32   1.9  
gi|24497478 solute carrier family 22 member 6 isoform c [Homo sa...    32   1.9  

>gi|208879454 solute carrier family 18 (vesicular monoamine), member
           1 isoform a [Homo sapiens]
          Length = 525

 Score = 1042 bits (2694), Expect = 0.0
 Identities = 525/525 (100%), Positives = 525/525 (100%)

Query: 1   MLRTILDAPQRLLKEGRASRQLVLVVVFVALLLDNMLFTVVVPIVPTFLYDMEFKEVNSS 60
           MLRTILDAPQRLLKEGRASRQLVLVVVFVALLLDNMLFTVVVPIVPTFLYDMEFKEVNSS
Sbjct: 1   MLRTILDAPQRLLKEGRASRQLVLVVVFVALLLDNMLFTVVVPIVPTFLYDMEFKEVNSS 60

Query: 61  LHLGHAGSSPHALASPAFSTIFSFFNNNTVAVEESVPSGIAWMNDTASTIPPPATEAISA 120
           LHLGHAGSSPHALASPAFSTIFSFFNNNTVAVEESVPSGIAWMNDTASTIPPPATEAISA
Sbjct: 61  LHLGHAGSSPHALASPAFSTIFSFFNNNTVAVEESVPSGIAWMNDTASTIPPPATEAISA 120

Query: 121 HKNNCLQGTGFLEEEITRVGVLFASKAVMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLS 180
           HKNNCLQGTGFLEEEITRVGVLFASKAVMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLS
Sbjct: 121 HKNNCLQGTGFLEEEITRVGVLFASKAVMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLS 180

Query: 181 TVMFAFSGTYTLLFVARTLQGIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGL 240
           TVMFAFSGTYTLLFVARTLQGIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGL
Sbjct: 181 TVMFAFSGTYTLLFVARTLQGIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGL 240

Query: 241 LVGAPFGSVMYEFVGKSAPFLILAFLALLDGALQLCILQPSKVSPESAKGTPLFMLLKDP 300
           LVGAPFGSVMYEFVGKSAPFLILAFLALLDGALQLCILQPSKVSPESAKGTPLFMLLKDP
Sbjct: 241 LVGAPFGSVMYEFVGKSAPFLILAFLALLDGALQLCILQPSKVSPESAKGTPLFMLLKDP 300

Query: 301 YILVAAGSICFANMGVAILEPTLPIWMMQTMCSPKWQLGLAFLPASVSYLIGTNLFGVLA 360
           YILVAAGSICFANMGVAILEPTLPIWMMQTMCSPKWQLGLAFLPASVSYLIGTNLFGVLA
Sbjct: 301 YILVAAGSICFANMGVAILEPTLPIWMMQTMCSPKWQLGLAFLPASVSYLIGTNLFGVLA 360

Query: 361 NKMGRWLCSLIGMLVVGTSLLCVPLAHNIFGLIGPNAGLGLAIGMVDSSMMPIMGHLVDL 420
           NKMGRWLCSLIGMLVVGTSLLCVPLAHNIFGLIGPNAGLGLAIGMVDSSMMPIMGHLVDL
Sbjct: 361 NKMGRWLCSLIGMLVVGTSLLCVPLAHNIFGLIGPNAGLGLAIGMVDSSMMPIMGHLVDL 420

Query: 421 RHTSVYGSVYAIADVAFCMGFAIGPSTGGAIVKAIGFPWLMVITGVINIVYAPLCYYLRS 480
           RHTSVYGSVYAIADVAFCMGFAIGPSTGGAIVKAIGFPWLMVITGVINIVYAPLCYYLRS
Sbjct: 421 RHTSVYGSVYAIADVAFCMGFAIGPSTGGAIVKAIGFPWLMVITGVINIVYAPLCYYLRS 480

Query: 481 PPAKEEKLAILSQDCPMETRMYATQKPTKEFPLGEDSDEEPDHEE 525
           PPAKEEKLAILSQDCPMETRMYATQKPTKEFPLGEDSDEEPDHEE
Sbjct: 481 PPAKEEKLAILSQDCPMETRMYATQKPTKEFPLGEDSDEEPDHEE 525


>gi|4506987 solute carrier family 18 (vesicular monoamine), member 1
           isoform a [Homo sapiens]
          Length = 525

 Score = 1042 bits (2694), Expect = 0.0
 Identities = 525/525 (100%), Positives = 525/525 (100%)

Query: 1   MLRTILDAPQRLLKEGRASRQLVLVVVFVALLLDNMLFTVVVPIVPTFLYDMEFKEVNSS 60
           MLRTILDAPQRLLKEGRASRQLVLVVVFVALLLDNMLFTVVVPIVPTFLYDMEFKEVNSS
Sbjct: 1   MLRTILDAPQRLLKEGRASRQLVLVVVFVALLLDNMLFTVVVPIVPTFLYDMEFKEVNSS 60

Query: 61  LHLGHAGSSPHALASPAFSTIFSFFNNNTVAVEESVPSGIAWMNDTASTIPPPATEAISA 120
           LHLGHAGSSPHALASPAFSTIFSFFNNNTVAVEESVPSGIAWMNDTASTIPPPATEAISA
Sbjct: 61  LHLGHAGSSPHALASPAFSTIFSFFNNNTVAVEESVPSGIAWMNDTASTIPPPATEAISA 120

Query: 121 HKNNCLQGTGFLEEEITRVGVLFASKAVMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLS 180
           HKNNCLQGTGFLEEEITRVGVLFASKAVMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLS
Sbjct: 121 HKNNCLQGTGFLEEEITRVGVLFASKAVMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLS 180

Query: 181 TVMFAFSGTYTLLFVARTLQGIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGL 240
           TVMFAFSGTYTLLFVARTLQGIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGL
Sbjct: 181 TVMFAFSGTYTLLFVARTLQGIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGL 240

Query: 241 LVGAPFGSVMYEFVGKSAPFLILAFLALLDGALQLCILQPSKVSPESAKGTPLFMLLKDP 300
           LVGAPFGSVMYEFVGKSAPFLILAFLALLDGALQLCILQPSKVSPESAKGTPLFMLLKDP
Sbjct: 241 LVGAPFGSVMYEFVGKSAPFLILAFLALLDGALQLCILQPSKVSPESAKGTPLFMLLKDP 300

Query: 301 YILVAAGSICFANMGVAILEPTLPIWMMQTMCSPKWQLGLAFLPASVSYLIGTNLFGVLA 360
           YILVAAGSICFANMGVAILEPTLPIWMMQTMCSPKWQLGLAFLPASVSYLIGTNLFGVLA
Sbjct: 301 YILVAAGSICFANMGVAILEPTLPIWMMQTMCSPKWQLGLAFLPASVSYLIGTNLFGVLA 360

Query: 361 NKMGRWLCSLIGMLVVGTSLLCVPLAHNIFGLIGPNAGLGLAIGMVDSSMMPIMGHLVDL 420
           NKMGRWLCSLIGMLVVGTSLLCVPLAHNIFGLIGPNAGLGLAIGMVDSSMMPIMGHLVDL
Sbjct: 361 NKMGRWLCSLIGMLVVGTSLLCVPLAHNIFGLIGPNAGLGLAIGMVDSSMMPIMGHLVDL 420

Query: 421 RHTSVYGSVYAIADVAFCMGFAIGPSTGGAIVKAIGFPWLMVITGVINIVYAPLCYYLRS 480
           RHTSVYGSVYAIADVAFCMGFAIGPSTGGAIVKAIGFPWLMVITGVINIVYAPLCYYLRS
Sbjct: 421 RHTSVYGSVYAIADVAFCMGFAIGPSTGGAIVKAIGFPWLMVITGVINIVYAPLCYYLRS 480

Query: 481 PPAKEEKLAILSQDCPMETRMYATQKPTKEFPLGEDSDEEPDHEE 525
           PPAKEEKLAILSQDCPMETRMYATQKPTKEFPLGEDSDEEPDHEE
Sbjct: 481 PPAKEEKLAILSQDCPMETRMYATQKPTKEFPLGEDSDEEPDHEE 525


>gi|215272390 solute carrier family 18 (vesicular monoamine), member
           1 isoform b [Homo sapiens]
          Length = 493

 Score =  956 bits (2472), Expect = 0.0
 Identities = 493/525 (93%), Positives = 493/525 (93%), Gaps = 32/525 (6%)

Query: 1   MLRTILDAPQRLLKEGRASRQLVLVVVFVALLLDNMLFTVVVPIVPTFLYDMEFKEVNSS 60
           MLRTILDAPQRLLKEGRASRQLVLVVVFVALLLDNMLFTVVVPIVPTFLYDMEFKEVNSS
Sbjct: 1   MLRTILDAPQRLLKEGRASRQLVLVVVFVALLLDNMLFTVVVPIVPTFLYDMEFKEVNSS 60

Query: 61  LHLGHAGSSPHALASPAFSTIFSFFNNNTVAVEESVPSGIAWMNDTASTIPPPATEAISA 120
           LHLGHAGSSPHALASPAFSTIFSFFNNNTVAVEESVPSGIAWMNDTASTIPPPATEAISA
Sbjct: 61  LHLGHAGSSPHALASPAFSTIFSFFNNNTVAVEESVPSGIAWMNDTASTIPPPATEAISA 120

Query: 121 HKNNCLQGTGFLEEEITRVGVLFASKAVMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLS 180
           HKNNCLQGTGFLEEEITRVGVLFASKAVMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLS
Sbjct: 121 HKNNCLQGTGFLEEEITRVGVLFASKAVMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLS 180

Query: 181 TVMFAFSGTYTLLFVARTLQGIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGL 240
           TVMFAFSGTYTLLFVARTLQGIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGL
Sbjct: 181 TVMFAFSGTYTLLFVARTLQGIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGL 240

Query: 241 LVGAPFGSVMYEFVGKSAPFLILAFLALLDGALQLCILQPSKVSPESAKGTPLFMLLKDP 300
           LVGAPFGSVMYEFVGKSAPFLILAFLALLDGALQLCILQPSKVSPESAKGTPLFMLLKDP
Sbjct: 241 LVGAPFGSVMYEFVGKSAPFLILAFLALLDGALQLCILQPSKVSPESAKGTPLFMLLKDP 300

Query: 301 YILVAAGSICFANMGVAILEPTLPIWMMQTMCSPKWQLGLAFLPASVSYLIGTNLFGVLA 360
           YILVAA                                GLAFLPASVSYLIGTNLFGVLA
Sbjct: 301 YILVAA--------------------------------GLAFLPASVSYLIGTNLFGVLA 328

Query: 361 NKMGRWLCSLIGMLVVGTSLLCVPLAHNIFGLIGPNAGLGLAIGMVDSSMMPIMGHLVDL 420
           NKMGRWLCSLIGMLVVGTSLLCVPLAHNIFGLIGPNAGLGLAIGMVDSSMMPIMGHLVDL
Sbjct: 329 NKMGRWLCSLIGMLVVGTSLLCVPLAHNIFGLIGPNAGLGLAIGMVDSSMMPIMGHLVDL 388

Query: 421 RHTSVYGSVYAIADVAFCMGFAIGPSTGGAIVKAIGFPWLMVITGVINIVYAPLCYYLRS 480
           RHTSVYGSVYAIADVAFCMGFAIGPSTGGAIVKAIGFPWLMVITGVINIVYAPLCYYLRS
Sbjct: 389 RHTSVYGSVYAIADVAFCMGFAIGPSTGGAIVKAIGFPWLMVITGVINIVYAPLCYYLRS 448

Query: 481 PPAKEEKLAILSQDCPMETRMYATQKPTKEFPLGEDSDEEPDHEE 525
           PPAKEEKLAILSQDCPMETRMYATQKPTKEFPLGEDSDEEPDHEE
Sbjct: 449 PPAKEEKLAILSQDCPMETRMYATQKPTKEFPLGEDSDEEPDHEE 493


>gi|215272392 solute carrier family 18 (vesicular monoamine), member
           1 isoform c [Homo sapiens]
          Length = 472

 Score =  877 bits (2266), Expect = 0.0
 Identities = 446/449 (99%), Positives = 446/449 (99%)

Query: 1   MLRTILDAPQRLLKEGRASRQLVLVVVFVALLLDNMLFTVVVPIVPTFLYDMEFKEVNSS 60
           MLRTILDAPQRLLKEGRASRQLVLVVVFVALLLDNMLFTVVVPIVPTFLYDMEFKEVNSS
Sbjct: 1   MLRTILDAPQRLLKEGRASRQLVLVVVFVALLLDNMLFTVVVPIVPTFLYDMEFKEVNSS 60

Query: 61  LHLGHAGSSPHALASPAFSTIFSFFNNNTVAVEESVPSGIAWMNDTASTIPPPATEAISA 120
           LHLGHAGSSPHALASPAFSTIFSFFNNNTVAVEESVPSGIAWMNDTASTIPPPATEAISA
Sbjct: 61  LHLGHAGSSPHALASPAFSTIFSFFNNNTVAVEESVPSGIAWMNDTASTIPPPATEAISA 120

Query: 121 HKNNCLQGTGFLEEEITRVGVLFASKAVMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLS 180
           HKNNCLQGTGFLEEEITRVGVLFASKAVMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLS
Sbjct: 121 HKNNCLQGTGFLEEEITRVGVLFASKAVMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLS 180

Query: 181 TVMFAFSGTYTLLFVARTLQGIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGL 240
           TVMFAFSGTYTLLFVARTLQGIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGL
Sbjct: 181 TVMFAFSGTYTLLFVARTLQGIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGL 240

Query: 241 LVGAPFGSVMYEFVGKSAPFLILAFLALLDGALQLCILQPSKVSPESAKGTPLFMLLKDP 300
           LVGAPFGSVMYEFVGKSAPFLILAFLALLDGALQLCILQPSKVSPESAKGTPLFMLLKDP
Sbjct: 241 LVGAPFGSVMYEFVGKSAPFLILAFLALLDGALQLCILQPSKVSPESAKGTPLFMLLKDP 300

Query: 301 YILVAAGSICFANMGVAILEPTLPIWMMQTMCSPKWQLGLAFLPASVSYLIGTNLFGVLA 360
           YILVAAGSICFANMGVAILEPTLPIWMMQTMCSPKWQLGLAFLPASVSYLIGTNLFGVLA
Sbjct: 301 YILVAAGSICFANMGVAILEPTLPIWMMQTMCSPKWQLGLAFLPASVSYLIGTNLFGVLA 360

Query: 361 NKMGRWLCSLIGMLVVGTSLLCVPLAHNIFGLIGPNAGLGLAIGMVDSSMMPIMGHLVDL 420
           NKMGRWLCSLIGMLVVGTSLLCVPLAHNIFGLIGPNAGLGLAIGMVDSSMMPIMGHLVDL
Sbjct: 361 NKMGRWLCSLIGMLVVGTSLLCVPLAHNIFGLIGPNAGLGLAIGMVDSSMMPIMGHLVDL 420

Query: 421 RHTSVYGSVYAIADVAFCMGFAIGPSTGG 449
           RHTSVYGSVYAIADVAFCMGFAIG S  G
Sbjct: 421 RHTSVYGSVYAIADVAFCMGFAIGYSESG 449


>gi|42476325 solute carrier family 18 (vesicular monoamine), member
           2 [Homo sapiens]
          Length = 514

 Score =  659 bits (1700), Expect = 0.0
 Identities = 331/513 (64%), Positives = 408/513 (79%), Gaps = 9/513 (1%)

Query: 11  RLLKEGRASRQLVLVVVFVALLLDNMLFTVVVPIVPTFLYDMEFKEVNSSLHLGHAGSSP 70
           R L+E R SR+L+L +VF+ALLLDNML TVVVPI+P++LY +  K   ++  +  A    
Sbjct: 10  RWLQESRRSRKLILFIVFLALLLDNMLLTVVVPIIPSYLYSI--KHEKNATEIQTARPVH 67

Query: 71  HALASPAFSTIFSFFNNNTVAVEESVPSGIAWMNDTASTIPPPATEAISAHKNNCLQGTG 130
            A  S +F +IFS+++N+T+    +          T   +    T A SA  ++C     
Sbjct: 68  TASISDSFQSIFSYYDNSTMVTGNATRDLTLHQTATQHMV----TNA-SAVPSDCPSEDK 122

Query: 131 FLEEEITRVGVLFASKAVMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLSTVMFAFSGTY 190
            L  E  +VG+LFASKA +QL+ NPF+G LTNRIGY IP+FAGF IMF+ST+MFAFS +Y
Sbjct: 123 DLLNENVQVGLLFASKATVQLITNPFIGLLTNRIGYPIPIFAGFCIMFVSTIMFAFSSSY 182

Query: 191 TLLFVARTLQGIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGLLVGAPFGSVM 250
             L +AR+LQGIGSS SSVAG+GMLASVYTDD ERG  MG ALGGLA+G+LVG PFGSV+
Sbjct: 183 AFLLIARSLQGIGSSCSSVAGMGMLASVYTDDEERGNVMGIALGGLAMGVLVGPPFGSVL 242

Query: 251 YEFVGKSAPFLILAFLALLDGALQLCILQPSKVSPESAKGTPLFMLLKDPYILVAAGSIC 310
           YEFVGK+APFL+LA L LLDGA+QL +LQPS+V PES KGTPL  LLKDPYIL+AAGSIC
Sbjct: 243 YEFVGKTAPFLVLAALVLLDGAIQLFVLQPSRVQPESQKGTPLTTLLKDPYILIAAGSIC 302

Query: 311 FANMGVAILEPTLPIWMMQTMCSPKWQLGLAFLPASVSYLIGTNLFGVLANKMGRWLCSL 370
           FANMG+A+LEP LPIWMM+TMCS KWQLG+AFLPAS+SYLIGTN+FG+LA+KMGRWLC+L
Sbjct: 303 FANMGIAMLEPALPIWMMETMCSRKWQLGVAFLPASISYLIGTNIFGILAHKMGRWLCAL 362

Query: 371 IGMLVVGTSLLCVPLAHNIFGLIGPNAGLGLAIGMVDSSMMPIMGHLVDLRHTSVYGSVY 430
           +GM++VG S+LC+P A NI+GLI PN G+G AIGMVDSSMMPIMG+LVDLRH SVYGSVY
Sbjct: 363 LGMIIVGVSILCIPFAKNIYGLIAPNFGVGFAIGMVDSSMMPIMGYLVDLRHVSVYGSVY 422

Query: 431 AIADVAFCMGFAIGPSTGGAIVKAIGFPWLMVITGVINIVYAPLCYYLRSPPAKEEKLAI 490
           AIADVAFCMG+AIGPS GGAI KAIGFPWLM I G+I+I++APLC++LRSPPAKEEK+AI
Sbjct: 423 AIADVAFCMGYAIGPSAGGAIAKAIGFPWLMTIIGIIDILFAPLCFFLRSPPAKEEKMAI 482

Query: 491 L-SQDCPMETRMYATQKPTKEFPLGEDSDEEPD 522
           L   +CP++T+MY TQ   + +P+GED + E D
Sbjct: 483 LMDHNCPIKTKMY-TQNNIQSYPIGEDEESESD 514


>gi|118582257 vesicular acetylcholine transporter [Homo sapiens]
          Length = 532

 Score =  339 bits (869), Expect = 4e-93
 Identities = 187/474 (39%), Positives = 276/474 (58%), Gaps = 33/474 (6%)

Query: 13  LKEGRASRQLVLVVVFVALLLDNMLFTVVVPIVPTFLYDMEFKEVNSSLHLGHAGSSPHA 72
           L+E R  R+LVLV+V VALLLDNML+ V+VPIVP ++            H+   G  P  
Sbjct: 25  LQEPRRQRRLVLVIVCVALLLDNMLYMVIVPIVPDYI-----------AHMRGGGEGP-- 71

Query: 73  LASPAFSTIFSFFNNNTVAVEESVPSGIAWMNDTASTIPPPATEAISAHKNNCLQGTGFL 132
                           T  V E         N +A T    A+   +    + L+     
Sbjct: 72  --------------TRTPEVWEPTLPLPTPANASAYTANTSASPTAAWPAGSALRPRYPT 117

Query: 133 EEEITRVGVLFASKAVMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLSTVMFAFSGTYTL 192
           E E  ++GVLFASKA++QLLVNP  GP  +R+ Y +P+  G  +MF STV+FAF+  Y  
Sbjct: 118 ESEDVKIGVLFASKAILQLLVNPLSGPFIDRMSYDVPLLIGLGVMFASTVLFAFAEDYAT 177

Query: 193 LFVARTLQGIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGLLVGAPFGSVMYE 252
           LF AR+LQG+GS+F+  +G+ M+A  Y ++ ER RA+G AL  ++ G LV  PFG ++YE
Sbjct: 178 LFAARSLQGLGSAFADTSGIAMIADKYPEEPERSRALGVALAFISFGSLVAPPFGGILYE 237

Query: 253 FVGKSAPFLILAFLALLDGALQLCILQPSKVSPESAK----GTPLFMLLKDPYILVAAGS 308
           F GK  PFL+LA ++L D  L L + +P   +  +      GTP+  L+ DPYI V AG+
Sbjct: 238 FAGKRVPFLVLAAVSLFDALLLLAVAKPFSAAARARANLPVGTPIHRLMLDPYIAVVAGA 297

Query: 309 ICFANMGVAILEPTLPIWMMQTMCSPKWQLGLAFLPASVSYLIGTNLFGVLANKMG--RW 366
           +   N+ +A LEPT+  WM  TM + +W++G+A+LPA V +++G  L   LA +    +W
Sbjct: 298 LTTCNIPLAFLEPTIATWMKHTMAASEWEMGMAWLPAFVPHVLGVYLTVRLAARYPHLQW 357

Query: 367 LCSLIGMLVVGTSLLCVPLAHNIFGLIGPNAGLGLAIGMVDSSMMPIMGHLVDLRHTSVY 426
           L   +G+ V+G S   VP   +   L+    GL   I +VD++++P +  LVD+RH SVY
Sbjct: 358 LYGALGLAVIGASSCIVPACRSFAPLVVSLCGLCFGIALVDTALLPTLAFLVDVRHVSVY 417

Query: 427 GSVYAIADVAFCMGFAIGPSTGGAIVKAIGFPWLMVITGVINIVYAPLCYYLRS 480
           GSVYAIAD+++ + +A+GP   G IV ++GF  L +  G+ N++YAP+   LR+
Sbjct: 418 GSVYAIADISYSVAYALGPIVAGHIVHSLGFEQLSLGMGLANLLYAPVLLLLRN 471


>gi|16445357 hypothetical protein LOC116843 [Homo sapiens]
          Length = 456

 Score =  106 bits (264), Expect = 6e-23
 Identities = 92/358 (25%), Positives = 157/358 (43%), Gaps = 42/358 (11%)

Query: 137 TRVGVLFASKAVMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLSTVMFAFSGTY------ 190
           T +G++F   A+ +LL +   G     IG      AG  +    T++F            
Sbjct: 70  TIIGMIFGCFALFELLASLVFGNYLVHIGAKFMFVAGMFVSGGVTILFGVLDRVPDGPVF 129

Query: 191 -TLLFVARTLQGIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGL----ALGLLVGAP 245
             + F+ R +  +  + +  A   +LA  + ++      + T LG L     LGL++G P
Sbjct: 130 IAMCFLVRVMDAVSFAAAMTASSSILAKAFPNN------VATVLGSLETFSGLGLILGPP 183

Query: 246 FGSVMYEFVGKSAPFLILAFLALLDGALQLCILQPSKVSPESAKGTPLFMLLKDPYILVA 305
            G  +Y+  G   PF++L  + LL   L + IL   +  P       L  L K   I   
Sbjct: 184 VGGFLYQSFGYEVPFIVLGCVVLLMVPLNMYILPNYESDPGEHSFWKLIALPKVGLIAFV 243

Query: 306 AGSI--CFANMGVAILEPTLPIWMMQTMCSPKWQLGLAFLPASVSYLIGTNLFGVLANK- 362
             S+  CF       L+PTL +++++    P   +GL FL  ++SY I + LFG+L++K 
Sbjct: 244 INSLSSCFG-----FLDPTLSLFVLEKFNLPAGYVGLVFLGMALSYAISSPLFGLLSDKR 298

Query: 363 --MGRWLCSLIGMLVVGTSLLC--VPLAH---NIFGLIGPNAGLGLAIGMVDSSMMPIMG 415
             + +WL     ++  G  +L   VP+ H    ++ L+      GL+ GM   S++P   
Sbjct: 299 PPLRKWLLVFGNLITAGCYMLLGPVPILHIKSQLWLLVLILVVSGLSAGM---SIIPTFP 355

Query: 416 HLVDLRH-------TSVYGSVYAIADVAFCMGFAIGPSTGGAIVKAIGFPWLMVITGV 466
            ++   H        S  G V  +    + +G  +GP+ GG + + IGF W   I G+
Sbjct: 356 EILSCAHENGFEEGLSTLGLVSGLFSAMWSIGAFMGPTLGGFLYEKIGFEWAAAIQGL 413



 Score = 35.0 bits (79), Expect = 0.17
 Identities = 46/202 (22%), Positives = 86/202 (42%), Gaps = 17/202 (8%)

Query: 287 SAKGTPLFMLLKDPYILVAAGSICFANMGV-AILEPTLPIWMMQTMCSPKWQLGLAFLPA 345
           SA  TP ++  +  ++L++A S+   +M   +IL P  P    +   S    +G+ F   
Sbjct: 21  SAGETPGWLSREQVFVLISAASVNLGSMMCYSILGPFFPKEAEKKGAS-NTIIGMIFGCF 79

Query: 346 SVSYLIGTNLFGVLANKMGRWLCSLIGMLVVG--TSLLCV-------PLAHNIFGLIGPN 396
           ++  L+ + +FG     +G     + GM V G  T L  V       P+   +  L+   
Sbjct: 80  ALFELLASLVFGNYLVHIGAKFMFVAGMFVSGGVTILFGVLDRVPDGPVFIAMCFLVRVM 139

Query: 397 AGLGLAIGMVDSSMMPIMGHLVDLRHTSVYGSVYAIADVAFCMGFAIGPSTGGAIVKAIG 456
             +  A  M  SS   I+         +V GS+   +     +G  +GP  GG + ++ G
Sbjct: 140 DAVSFAAAMTASSS--ILAKAFPNNVATVLGSLETFSG----LGLILGPPVGGFLYQSFG 193

Query: 457 FPWLMVITGVINIVYAPLCYYL 478
           +    ++ G + ++  PL  Y+
Sbjct: 194 YEVPFIVLGCVVLLMVPLNMYI 215


>gi|213021148 SVOP-like isoform 1 [Homo sapiens]
          Length = 492

 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 42/216 (19%), Positives = 80/216 (37%), Gaps = 13/216 (6%)

Query: 259 PFLILAFLALLDGALQLCILQPSKVSPESAKGTPLFMLLKDPYILVAAGSICFANMGVAI 318
           P  IL+   L  G  +  + +P   + E A  T  F        L+   +     M + +
Sbjct: 8   PVTILSLRKLSLGTAEPQVKEPKTFTVEDAVETIGFGRFHIALFLIMGSTGVVEAMEIML 67

Query: 319 LEPTLPI----WMMQTMCSPKWQLGLAFLPASVSYLIGTNLFGVLANKMGRWLCSLIGML 374
           +    P+    W ++      WQ+ L        Y++ + LFG+LA++ GRW   LI  L
Sbjct: 68  IAVVSPVIRCEWQLEN-----WQVALVTTMVFFGYMVFSILFGLLADRYGRWKILLISFL 122

Query: 375 VVGTSLLCVPLAHNIFGLIGPNAGLGLAIGMVDSSMMPIMGHLVDLRHTSVYGSVYAIAD 434
                 L    A +    +     +G  +      ++       +   T   G +  ++ 
Sbjct: 123 WGAYFSLLTSFAPSYIWFVFLRTMVGCGVSGHSQGLI----IKTEFLPTKYRGYMLPLSQ 178

Query: 435 VAFCMGFAIGPSTGGAIVKAIGFPWLMVITGVINIV 470
           V +  G  +       I+  IG+ WL+ +  +  I+
Sbjct: 179 VFWLAGSLLIIGLASVIIPTIGWRWLIRVASIPGII 214


>gi|6912666 sialin [Homo sapiens]
          Length = 495

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 71/342 (20%), Positives = 139/342 (40%), Gaps = 30/342 (8%)

Query: 73  LASPAFSTIFSFFNNNTVAVEESVPSGIAWMNDTASTIPPPATEAISAHKNNCLQGTGFL 132
           LA   F  +++   N +VA+ + V S     ++  S   P  +  I  H N    G  + 
Sbjct: 45  LAFFGFFIVYALRVNLSVALVDMVDSNTTLEDNRTSKACPEHSAPIKVHHNQT--GKKYQ 102

Query: 133 EEEITRVGVLFASKAVMQLLVNPFVGPLTNRIGYHIPM---FAGFVIMFLSTVMFAFSGT 189
            +  T+ G +  S     ++     G + ++IG  + +     G  ++ L T + A  G 
Sbjct: 103 WDAETQ-GWILGSFFYGYIITQIPGGYVASKIGGKMLLGFGILGTAVLTLFTPIAADLGV 161

Query: 190 YTLLFVARTLQGIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGLLVGAPFGSV 249
             L+ V R L+G+G   +  A   M +S +    ER + +  +  G  LG ++  P   +
Sbjct: 162 GPLI-VLRALEGLGEGVTFPAMHAMWSS-WAPPLERSKLLSISYAGAQLGTVISLPLSGI 219

Query: 250 MYEFVGKSAPFLILAFLALLDGALQLCILQPSKVSPESAKGTPLFMLLKDPYILVAAGSI 309
           +  ++  +  F     + +    L + ++  +   P+  K    +   +  YIL +  + 
Sbjct: 220 ICYYMNWTYVFYFFGTIGIFWFLLWIWLVSDT---PQKHKRISHY---EKEYILSSLRNQ 273

Query: 310 CFANMGVAILE--PTLPIW-MMQTMCSPKWQLG--LAFLPASVSYLIGTNLF--GVLANK 362
             +   V  +    +LP+W ++    S  W     L  LP  +  ++  N+   G L++ 
Sbjct: 274 LSSQKSVPWVPILKSLPLWAIVVAHFSYNWTFYTLLTLLPTYMKEILRFNVQENGFLSSL 333

Query: 363 --MGRWLCSLIGMLVVGT-------SLLCVPLAHNIFGLIGP 395
             +G WLC ++              S LCV    ++ G+IGP
Sbjct: 334 PYLGSWLCMILSGQAADNLRAKWNFSTLCVRRIFSLIGMIGP 375


>gi|24431958 solute carrier family 16, member 7 [Homo sapiens]
          Length = 478

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 33/127 (25%), Positives = 59/127 (46%), Gaps = 4/127 (3%)

Query: 155 PFVGPLTNRIGYHIPMFAGFVIMFLSTVMFAFSGTYTLLFVART-LQGIGSSFSSVAGLG 213
           P    L N+ G    + AG ++  L  V+ +FS +   L++    + G+G +F+    L 
Sbjct: 74  PVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFITGLGLAFNLQPALT 133

Query: 214 MLASVYTDDHERGRAMGTALGGLALGLLVGAPFGSVMYEFVGKSAPFLILAFLALLDGAL 273
           ++   +    +R  A G A+ G  + L   APF   ++   G    FLIL  L LL+  +
Sbjct: 134 IIGKYFY--RKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLILGSL-LLNACV 190

Query: 274 QLCILQP 280
              +++P
Sbjct: 191 AGSLMRP 197


>gi|115583685 solute carrier family 16, member 1 [Homo sapiens]
          Length = 500

 Score = 40.0 bits (92), Expect = 0.005
 Identities = 39/142 (27%), Positives = 59/142 (41%), Gaps = 7/142 (4%)

Query: 155 PFVGPLTNRIGYHIPMFAGFVIMFLSTVMFAFSGTYTLLFVA-RTLQGIGSSFSSVAGLG 213
           P    L N+ G  I M  G  +     +  +F  T   L+V    + G+G +F+    L 
Sbjct: 74  PISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIGGLGLAFNLNPALT 133

Query: 214 MLASVYTDDHERGRAMGTALGGLALGLLVGAPFGSVMYEFVGKSAPFLILAFLAL---LD 270
           M+   +     R  A G A+ G  + L   AP   V +   G    FLIL  L L   + 
Sbjct: 134 MIGKYFYK--RRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLILGGLLLNCCVA 191

Query: 271 GALQLCI-LQPSKVSPESAKGT 291
           GAL   I  +P+K   + +K +
Sbjct: 192 GALMRPIGPKPTKAGKDKSKAS 213


>gi|109288010 solute carrier family 16, member 3 [Homo sapiens]
          Length = 465

 Score = 37.7 bits (86), Expect = 0.026
 Identities = 41/170 (24%), Positives = 73/170 (42%), Gaps = 11/170 (6%)

Query: 131 FLEEEITRVGVLFASKAVMQLLVNPFV---GPL----TNRIGYHIPMFAGFVIMFLSTVM 183
           F +E I   G+ ++  A +  ++   +   GPL     NR G    M  G +   L  V 
Sbjct: 45  FFKELIQEFGIGYSDTAWISSILLAMLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVA 104

Query: 184 FAFSGTYTLLFVAR-TLQGIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGLLV 242
            +F  +   +++    + G+G + +    L ML   ++    R  A G A  G  + L  
Sbjct: 105 ASFCRSIIQVYLTTGVITGLGLALNFQPSLIMLNRYFSK--RRPMANGLAAAGSPVFLCA 162

Query: 243 GAPFGSVMYEFVGKSAPFLILAFLALLDGALQLCILQPSKVSPESAKGTP 292
            +P G ++ +  G    FLIL  L LL+  +   +++P  V+ +   G P
Sbjct: 163 LSPLGQLLQDRYGWRGGFLILGGL-LLNCCVCAALMRPLVVTAQPGSGPP 211


>gi|109288012 solute carrier family 16, member 3 [Homo sapiens]
          Length = 465

 Score = 37.7 bits (86), Expect = 0.026
 Identities = 41/170 (24%), Positives = 73/170 (42%), Gaps = 11/170 (6%)

Query: 131 FLEEEITRVGVLFASKAVMQLLVNPFV---GPL----TNRIGYHIPMFAGFVIMFLSTVM 183
           F +E I   G+ ++  A +  ++   +   GPL     NR G    M  G +   L  V 
Sbjct: 45  FFKELIQEFGIGYSDTAWISSILLAMLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVA 104

Query: 184 FAFSGTYTLLFVAR-TLQGIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGLLV 242
            +F  +   +++    + G+G + +    L ML   ++    R  A G A  G  + L  
Sbjct: 105 ASFCRSIIQVYLTTGVITGLGLALNFQPSLIMLNRYFSK--RRPMANGLAAAGSPVFLCA 162

Query: 243 GAPFGSVMYEFVGKSAPFLILAFLALLDGALQLCILQPSKVSPESAKGTP 292
            +P G ++ +  G    FLIL  L LL+  +   +++P  V+ +   G P
Sbjct: 163 LSPLGQLLQDRYGWRGGFLILGGL-LLNCCVCAALMRPLVVTAQPGSGPP 211


>gi|4759112 solute carrier family 16, member 3 [Homo sapiens]
          Length = 465

 Score = 37.7 bits (86), Expect = 0.026
 Identities = 41/170 (24%), Positives = 73/170 (42%), Gaps = 11/170 (6%)

Query: 131 FLEEEITRVGVLFASKAVMQLLVNPFV---GPL----TNRIGYHIPMFAGFVIMFLSTVM 183
           F +E I   G+ ++  A +  ++   +   GPL     NR G    M  G +   L  V 
Sbjct: 45  FFKELIQEFGIGYSDTAWISSILLAMLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVA 104

Query: 184 FAFSGTYTLLFVAR-TLQGIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGLLV 242
            +F  +   +++    + G+G + +    L ML   ++    R  A G A  G  + L  
Sbjct: 105 ASFCRSIIQVYLTTGVITGLGLALNFQPSLIMLNRYFSK--RRPMANGLAAAGSPVFLCA 162

Query: 243 GAPFGSVMYEFVGKSAPFLILAFLALLDGALQLCILQPSKVSPESAKGTP 292
            +P G ++ +  G    FLIL  L LL+  +   +++P  V+ +   G P
Sbjct: 163 LSPLGQLLQDRYGWRGGFLILGGL-LLNCCVCAALMRPLVVTAQPGSGPP 211


>gi|4759116 solute carrier family 16, member 5 [Homo sapiens]
          Length = 505

 Score = 37.7 bits (86), Expect = 0.026
 Identities = 36/146 (24%), Positives = 64/146 (43%), Gaps = 10/146 (6%)

Query: 152 LVNPFVGPLTNRIGYHIPMFAGFVIMFLSTVMFAFSGTYT-LLFVARTLQGIGSSFSSVA 210
           +  P    L  R G  + +  G V+  L  V  +FS   + L F A  + G+G  FS  +
Sbjct: 65  MAGPLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCFSFQS 124

Query: 211 GLGMLASVYTDDHERGRAMGTALG--GLALGLLVGAPFGSVMYEFVGKSAPFLILAFLAL 268
            + +L   +     R R +  AL   G++LG+ +       + E +G    FL+   +  
Sbjct: 125 SITVLGFYFV----RRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGI-F 179

Query: 269 LDGALQLCILQP--SKVSPESAKGTP 292
           L   +   I++P  + V+PE+ +  P
Sbjct: 180 LHCCICGAIIRPVATSVAPETKECPP 205


>gi|225703102 major facilitator superfamily domain containing 10
           [Homo sapiens]
          Length = 455

 Score = 37.4 bits (85), Expect = 0.034
 Identities = 57/256 (22%), Positives = 98/256 (38%), Gaps = 61/256 (23%)

Query: 23  VLVVVFVALLLDNMLFTVVVPIVPTFLYDMEFKEVNSSLHLGHAGSSPHALASPAFSTIF 82
           V+ VVF+ LLLD + FT+++P++P  L      E +   H             P +    
Sbjct: 24  VVTVVFLGLLLDLLAFTLLLPLLPGLL------ESHGRAH------------DPLYG--- 62

Query: 83  SFFNNNTVAVEESVPSGIAWMNDTASTIPPPATEAISAHKNNCLQGTGFLEEEITRVGVL 142
                       S   G+ W    A+ I  P    +    N+ L G           G++
Sbjct: 63  ------------SWQGGVDWF---ATAIGMP----VEKRYNSVLFG-----------GLI 92

Query: 143 FASKAVMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLSTVMFAFSGTYTLLFVARTLQGI 202
            ++ +V+Q L  P  G  ++ +G    M    + +  S  ++A S ++     +R + GI
Sbjct: 93  GSAFSVLQFLCAPLTGATSDCLGRRPVMLLCLMGVATSYAVWATSRSFAAFLASRLIGGI 152

Query: 203 GSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGLLVGAPFGSVMYEFVGKSAPFLI 262
                S++     A V        R+ G A+ G+A  L      G  +   +G S P  +
Sbjct: 153 SKGNVSLS----TAIVADLGSPLARSQGMAVIGVAFSL------GFTLGPMLGASLPLEM 202

Query: 263 LAFLALLDGALQLCIL 278
             + ALL  A  L  +
Sbjct: 203 APWFALLFAASDLLFI 218



 Score = 33.9 bits (76), Expect = 0.37
 Identities = 33/153 (21%), Positives = 64/153 (41%), Gaps = 9/153 (5%)

Query: 338 LGLAFLPASVSYLIGTNLFGVLANKMGRWLCSLIGMLVVGTSLLCVPLAHNIFGLIGPNA 397
           +G AF   SV   +   L G  ++ +GR    L+ ++ V TS      + +    +    
Sbjct: 92  IGSAF---SVLQFLCAPLTGATSDCLGRRPVMLLCLMGVATSYAVWATSRSFAAFLASRL 148

Query: 398 GLGLAIGMVDSSMMPIMGHLVDLRHTSVYGSVYAIADVAFCMGFAIGPSTGGAIVKAIGF 457
             G++ G V  S   +     DL          A+  VAF +GF +GP  G ++   +  
Sbjct: 149 IGGISKGNVSLSTAIV----ADLGSPLARSQGMAVIGVAFSLGFTLGPMLGASLPLEMA- 203

Query: 458 PWLMVITGVINIVYAPLCYYLRSPPAKEEKLAI 490
           PW  ++    ++++   C+   + P ++   +I
Sbjct: 204 PWFALLFAASDLLFI-FCFLPETLPLEKRAPSI 235


>gi|169217968 PREDICTED: similar to solute carrier family 16, member
           5 [Homo sapiens]
          Length = 453

 Score = 37.4 bits (85), Expect = 0.034
 Identities = 37/150 (24%), Positives = 66/150 (44%), Gaps = 10/150 (6%)

Query: 148 VMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLSTVMFAFSGTYT-LLFVARTLQGIGSSF 206
           ++ L   P    L  R G  + +  G V+  L  V  +FS   + L F A  + G+G  F
Sbjct: 9   LVALSERPLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCF 68

Query: 207 SSVAGLGMLASVYTDDHERGRAMGTALG--GLALGLLVGAPFGSVMYEFVGKSAPFLILA 264
           S  + + +L   +     R R +  AL   G++LG+ +       + E +G    FL+  
Sbjct: 69  SFQSSITVLGFYFV----RRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFG 124

Query: 265 FLALLDGALQLCILQP--SKVSPESAKGTP 292
            +  L   +   I++P  + V+PE+ +  P
Sbjct: 125 GI-FLHCCICGAIIRPVATSVAPETKECPP 153


>gi|225703104 major facilitator superfamily domain containing 10
           [Homo sapiens]
          Length = 455

 Score = 37.4 bits (85), Expect = 0.034
 Identities = 57/256 (22%), Positives = 98/256 (38%), Gaps = 61/256 (23%)

Query: 23  VLVVVFVALLLDNMLFTVVVPIVPTFLYDMEFKEVNSSLHLGHAGSSPHALASPAFSTIF 82
           V+ VVF+ LLLD + FT+++P++P  L      E +   H             P +    
Sbjct: 24  VVTVVFLGLLLDLLAFTLLLPLLPGLL------ESHGRAH------------DPLYG--- 62

Query: 83  SFFNNNTVAVEESVPSGIAWMNDTASTIPPPATEAISAHKNNCLQGTGFLEEEITRVGVL 142
                       S   G+ W    A+ I  P    +    N+ L G           G++
Sbjct: 63  ------------SWQGGVDWF---ATAIGMP----VEKRYNSVLFG-----------GLI 92

Query: 143 FASKAVMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLSTVMFAFSGTYTLLFVARTLQGI 202
            ++ +V+Q L  P  G  ++ +G    M    + +  S  ++A S ++     +R + GI
Sbjct: 93  GSAFSVLQFLCAPLTGATSDCLGRRPVMLLCLMGVATSYAVWATSRSFAAFLASRLIGGI 152

Query: 203 GSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGLLVGAPFGSVMYEFVGKSAPFLI 262
                S++     A V        R+ G A+ G+A  L      G  +   +G S P  +
Sbjct: 153 SKGNVSLS----TAIVADLGSPLARSQGMAVIGVAFSL------GFTLGPMLGASLPLEM 202

Query: 263 LAFLALLDGALQLCIL 278
             + ALL  A  L  +
Sbjct: 203 APWFALLFAASDLLFI 218



 Score = 33.9 bits (76), Expect = 0.37
 Identities = 33/153 (21%), Positives = 64/153 (41%), Gaps = 9/153 (5%)

Query: 338 LGLAFLPASVSYLIGTNLFGVLANKMGRWLCSLIGMLVVGTSLLCVPLAHNIFGLIGPNA 397
           +G AF   SV   +   L G  ++ +GR    L+ ++ V TS      + +    +    
Sbjct: 92  IGSAF---SVLQFLCAPLTGATSDCLGRRPVMLLCLMGVATSYAVWATSRSFAAFLASRL 148

Query: 398 GLGLAIGMVDSSMMPIMGHLVDLRHTSVYGSVYAIADVAFCMGFAIGPSTGGAIVKAIGF 457
             G++ G V  S   +     DL          A+  VAF +GF +GP  G ++   +  
Sbjct: 149 IGGISKGNVSLSTAIV----ADLGSPLARSQGMAVIGVAFSLGFTLGPMLGASLPLEMA- 203

Query: 458 PWLMVITGVINIVYAPLCYYLRSPPAKEEKLAI 490
           PW  ++    ++++   C+   + P ++   +I
Sbjct: 204 PWFALLFAASDLLFI-FCFLPETLPLEKRAPSI 235


>gi|34916028 solute carrier family 16 (monocarboxylic acid
           transporters), member 9 [Homo sapiens]
          Length = 509

 Score = 36.6 bits (83), Expect = 0.058
 Identities = 30/119 (25%), Positives = 50/119 (42%), Gaps = 3/119 (2%)

Query: 151 LLVNPFVGPLTNRIGYH-IPMFAGFVIMFLSTVMFAFSGTYTLLFVARTLQGIGSSFSSV 209
           LL +P      +  G   + +F+GF++     +       Y L F    + G+G      
Sbjct: 63  LLASPVCSLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLGCGLLYT 122

Query: 210 AGLGMLASVYTDDHERGRAMGTALGGLALGLLVGAPFGSVMYEFVGKSAPFLILAFLAL 268
           A + +    + D   RG A+G    G ++GL + A    ++ EF G     LI+  LAL
Sbjct: 123 ATVTITCQYFDD--RRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALAL 179


>gi|24308167 SV2 related protein [Homo sapiens]
          Length = 548

 Score = 35.8 bits (81), Expect = 0.099
 Identities = 38/175 (21%), Positives = 77/175 (44%), Gaps = 28/175 (16%)

Query: 314 MGVAILEPTLPI-WMMQTMCSPKWQLGLAFLPASVSYLIGTNLFGVLANKMGRWL---CS 369
           M ++IL P L   W +     P WQ+ L      V  +  + L+G ++++ GR      S
Sbjct: 102 MILSILAPQLHCEWRL-----PSWQVALLTSVVFVGMMSSSTLWGNISDQYGRKTGLKIS 156

Query: 370 LIGMLVVGTSLLCVPLAHNIFGLIGPNAGLGLAIGMVDSSM------MPIMGHLVDLRHT 423
           ++  L  G      P+   I  L G    +G  IG V  S+      +P+      +   
Sbjct: 157 VLWTLYYGILSAFAPVYSWILVLRGL---VGFGIGGVPQSVTLYAEFLPMKARAKCILLI 213

Query: 424 SVYGSVYAIADVAFCMGFAIGPSTGGAIVKAIGFPWLMVITGVINIVYAPLCYYL 478
            V+ ++  + +V   +           ++ ++G+ WL++++ V  +++A LC++L
Sbjct: 214 EVFWAIGTVFEVVLAV----------FVMPSLGWRWLLILSAVPLLLFAVLCFWL 258


>gi|4507021 solute carrier family 4, anion exchanger, member 1 [Homo
           sapiens]
          Length = 911

 Score = 35.4 bits (80), Expect = 0.13
 Identities = 26/83 (31%), Positives = 41/83 (49%), Gaps = 13/83 (15%)

Query: 140 GVLFASKAVMQLLVNPFVGPL------------TNRIGYHIP-MFAGFVIMFLSTVMFAF 186
           G+LFA      LLV  F GPL            TN + Y +  ++ GF ++ L  ++ AF
Sbjct: 448 GILFALLGAQPLLVVGFSGPLLVFEEAFFSFCETNGLEYIVGRVWIGFWLILLVVLVVAF 507

Query: 187 SGTYTLLFVARTLQGIGSSFSSV 209
            G++ + F++R  Q I S   S+
Sbjct: 508 EGSFLVRFISRYTQEIFSFLISL 530


>gi|4507001 solute carrier family 22 member 2 [Homo sapiens]
          Length = 555

 Score = 35.4 bits (80), Expect = 0.13
 Identities = 37/153 (24%), Positives = 63/153 (41%), Gaps = 20/153 (13%)

Query: 331 MCSPKWQLGLAFLPASVSYLIGTNLFGVLANKMGRWLCSLIGMLVVGTSLLCVPLAHN-- 388
           +C+  W L L     +V + IG+   G +A++ GR LC L  +L+   + + + ++    
Sbjct: 142 VCANSWMLDLFQSSVNVGFFIGSMSIGYIADRFGRKLCLLTTVLINAAAGVLMAISPTYT 201

Query: 389 ---IFGLI-GPNAGLGLAIGMVDSSMMPIMGHLVDLRHTSVYGSVYAIADVAFCMGFAIG 444
              IF LI G  +  G  IG +      ++   V  R+    G  Y    VA+ +G  + 
Sbjct: 202 WMLIFRLIQGLVSKAGWLIGYI------LITEFVGRRYRRTVGIFY---QVAYTVGLLV- 251

Query: 445 PSTGGAIVKAIGFPWLMVITGVINIVYAPLCYY 477
               G       + WL     + N  +  L YY
Sbjct: 252 --LAGVAYALPHWRWLQFTVALPNFFF--LLYY 280



 Score = 29.6 bits (65), Expect = 7.1
 Identities = 15/55 (27%), Positives = 28/55 (50%)

Query: 157 VGPLTNRIGYHIPMFAGFVIMFLSTVMFAFSGTYTLLFVARTLQGIGSSFSSVAG 211
           +G + +R G  + +    +I   + V+ A S TYT + + R +QG+ S    + G
Sbjct: 167 IGYIADRFGRKLCLLTTVLINAAAGVLMAISPTYTWMLIFRLIQGLVSKAGWLIG 221


>gi|5730045 solute carrier family 16, member 2 [Homo sapiens]
          Length = 613

 Score = 35.4 bits (80), Expect = 0.13
 Identities = 84/404 (20%), Positives = 147/404 (36%), Gaps = 49/404 (12%)

Query: 149 MQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLSTVMFAFSGTYTL-LFVARTLQGIGSSFS 207
           M    +P V   T+R+G  I   AG  + F+     +F+ + +L  F    L G G SF+
Sbjct: 227 MIFFCSPIVSIFTDRLGCRITATAGAAVAFIGLHTSSFTSSLSLRYFTYGILFGCGCSFA 286

Query: 208 SVAGLGMLASVYTDDHERGRAMGTALGGLALGLLVGAPFGSVMYEFVGK----SAPFLIL 263
               L +L       H   R +G A G ++ G  + +     +   +G     +  F +L
Sbjct: 287 FQPSLVILG------HYFQRRLGLANGVVSAGSSIFSMSFPFLIRMLGDKIKLAQTFQVL 340

Query: 264 AFLALLDGALQLCI--LQPSKVSPESAKGTPLF--------------MLLKDPYILVAAG 307
           +    +   L L    L PS     S +G                   + +     + A 
Sbjct: 341 STFMFVLMLLSLTYRPLLPSSQDTPSKRGVRTLHQRFLAQLRKYFNMRVFRQRTYRIWAF 400

Query: 308 SICFANMGVAILEPTLPIWMMQTMCSPKWQLGLAFLPASVSYLIGTNLFGVLANK---MG 364
            I  A +G  +    L  ++ +     K    L     + S L G  + G +++    + 
Sbjct: 401 GIAAAALGYFVPYVHLMKYVEEEFSEIKETWVLLVCIGATSGL-GRLVSGHISDSIPGLK 459

Query: 365 RWLCSLIGMLVVGTSLLCVPLAHNIFGLIGPNAGLGLAIGMVDSSMMPIMGHLVDLRHTS 424
           +    ++  L++G   + +PL  +  GLI     LGL  G   + M PI   LV      
Sbjct: 460 KIYLQVLSFLLLGLMSMMIPLCRDFGGLIVVCLFLGLCDGFFITIMAPIAFELV------ 513

Query: 425 VYGSVYAIADVAFCMG-----FAIGPSTGGAIVKAIG-FPWLMVITGVINIVYAPLCYYL 478
             G + A   + + +G        GP   G +    G +       GV  I+ A + +++
Sbjct: 514 --GPMQASQAIGYLLGMMALPMIAGPPIAGLLRNCFGDYHVAFYFAGVPPIIGAVILFFV 571

Query: 479 RSPPAKEEKLAILSQDCPMETRMYATQ-KPTKEFPLGEDSDEEP 521
              P   +++    Q    + +M A    P  E   G  + EEP
Sbjct: 572 ---PLMHQRMFKKEQRDSSKDKMLAPDPDPNGELLPGSPNPEEP 612


>gi|21553331 solute carrier family 2 (facilitated glucose
           transporter), member 12 [Homo sapiens]
          Length = 617

 Score = 35.0 bits (79), Expect = 0.17
 Identities = 25/101 (24%), Positives = 47/101 (46%), Gaps = 1/101 (0%)

Query: 141 VLFASKAVMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLSTVMFAFSGTYTLLFVARTLQ 200
           ++ +S  +  LL +   G L +R G    +     ++ L +++   S +YT+L V R   
Sbjct: 81  MVVSSLVIGALLASLTGGVLIDRYGRRTAIILSSCLLGLGSLVLILSLSYTVLIVGRIAI 140

Query: 201 GIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGLL 241
           G+  S SS+A    +A +    H RG  +      + +G+L
Sbjct: 141 GVSISLSSIATCVYIAEI-APQHRRGLLVSLNELMIVIGIL 180


>gi|156071474 solute carrier family 4, anion exchanger, member 2
           (erythrocyte membrane protein band 3-like 1) [Homo
           sapiens]
          Length = 1241

 Score = 34.7 bits (78), Expect = 0.22
 Identities = 30/109 (27%), Positives = 46/109 (42%), Gaps = 13/109 (11%)

Query: 107 ASTIPPPATEAISAHKNNCLQGTGFLEEEITRVGVLFASKAVMQLLVNPFVGPL------ 160
           A+  P      +   K   L G   L       GV+F       LLV  F GPL      
Sbjct: 718 AALSPAITFGGLLGEKTQDLIGVSELIMSTALQGVVFCLLGAQPLLVIGFSGPLLVFEEA 777

Query: 161 ------TNRIGYHIP-MFAGFVIMFLSTVMFAFSGTYTLLFVARTLQGI 202
                 +N + Y +  ++ GF ++FL+ +M A  G++ + FV+R  Q I
Sbjct: 778 FFSFCSSNHLEYLVGRVWIGFWLVFLALLMVALEGSFLVRFVSRFTQEI 826


>gi|4503847 solute carrier family 37 (glucose-6-phosphate
           transporter), member 4 [Homo sapiens]
          Length = 429

 Score = 33.5 bits (75), Expect = 0.49
 Identities = 38/151 (25%), Positives = 65/151 (43%), Gaps = 17/151 (11%)

Query: 335 KWQLGLAFLPASVSYLIGTNLFGVLANKMG-RWLCSLIGMLVVGTSLL------CVPLAH 387
           K  LG      S +Y I   + GVL+++M  RWL S  G+L+VG   +       VP+  
Sbjct: 46  KDDLGFITSSQSAAYAISKFVSGVLSDQMSARWLFSS-GLLLVGLVNIFFAWSSTVPVFA 104

Query: 388 NIFGLIGPNAGLGLAIGMVDSSMMPIMGHLVDLRHTSVYGSVYAIADVAFCMGFAIGPST 447
            ++ L G   GLG           P    L      S +G+ +AI   +  +   +GP  
Sbjct: 105 ALWFLNGLAQGLGWP---------PCGKVLRKWFEPSQFGTWWAILSTSMNLAGGLGPIL 155

Query: 448 GGAIVKAIGFPWLMVITGVINIVYAPLCYYL 478
              + ++  +   + ++G + +V + LC  L
Sbjct: 156 ATILAQSYSWRSTLALSGALCVVVSFLCLLL 186


>gi|114796626 solute carrier family 16, member 8 [Homo sapiens]
          Length = 504

 Score = 33.1 bits (74), Expect = 0.64
 Identities = 31/115 (26%), Positives = 48/115 (41%), Gaps = 3/115 (2%)

Query: 155 PFVGPLTNRIGYHIPMFAGFVIMFLSTVMFAFSGTYTLLFV-ARTLQGIGSSFSSVAGLG 213
           P    L  R G    M AG ++     ++ +F+     L++ A  L G+G + +    L 
Sbjct: 73  PVSSILVTRFGCRPVMLAGGLLASAGMILASFATRLLELYLTAGVLTGLGLALNFQPSLI 132

Query: 214 MLASVYTDDHERGRAMGTALGGLALGLLVGAPFGSVMYEFVGKSAPFLILAFLAL 268
           ML   +  +  R  A G A  G  + L   +P G  + E  G    FL+L  L L
Sbjct: 133 MLGLYF--ERRRPLANGLAAAGSPVFLSALSPLGQQLLERFGWRGGFLLLGGLLL 185


>gi|42542381 solute carrier family 28, member 1 isoform 1 [Homo
           sapiens]
          Length = 649

 Score = 32.3 bits (72), Expect = 1.1
 Identities = 35/140 (25%), Positives = 60/140 (42%), Gaps = 9/140 (6%)

Query: 134 EEITRVGVLFASKAVMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLSTVMFAFSGTYTLL 193
           E ++  G +F S+    LL+ P++  +T     H+ M  G+     +T+  +  G Y   
Sbjct: 307 ETLSVAGNIFVSQTEAPLLIRPYLADMT-LSEVHVVMTGGY-----ATIAGSLLGAYISF 360

Query: 194 FVARTLQGIGSSFSSVAGLGMLASVYTDDHER--GRAMGTALG-GLALGLLVGAPFGSVM 250
            +  T     S  ++   L +   VY +  E    R  G  L  G A  L+  A  G+ +
Sbjct: 361 GIDATSLIAASVMAAPCALALSKLVYPEVEESKFRREEGVKLTYGDAQNLIEAASTGAAI 420

Query: 251 YEFVGKSAPFLILAFLALLD 270
              V  +    ++AFLA+LD
Sbjct: 421 SVKVVANIAANLIAFLAVLD 440


>gi|24497480 solute carrier family 22 member 6 isoform d [Homo
           sapiens]
          Length = 519

 Score = 31.6 bits (70), Expect = 1.9
 Identities = 31/128 (24%), Positives = 54/128 (42%), Gaps = 16/128 (12%)

Query: 321 PTLPIWMMQTMCSPKWQLGLAFLPASVSYLIGTNLFGVLANKMGRWLCSLIGMLVVGTSL 380
           P+  +     +CS +    LA     V  L+G  +FG LA+++GR    ++  L    S 
Sbjct: 117 PSTIVTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSG 176

Query: 381 LCVPLAHNI-----FGLIGPNAGLGLAIGMVDSSM--MPI---------MGHLVDLRHTS 424
            C   A N      F L+   A  G+++  +  ++  MPI         +G++  L    
Sbjct: 177 TCAAFAPNFPIYCAFRLLSGMALAGISLNCMTLNVEWMPIHTRACVGTLIGYVYSLGQFL 236

Query: 425 VYGSVYAI 432
           + G  YA+
Sbjct: 237 LAGVAYAV 244


>gi|24497478 solute carrier family 22 member 6 isoform c [Homo
           sapiens]
          Length = 506

 Score = 31.6 bits (70), Expect = 1.9
 Identities = 31/128 (24%), Positives = 54/128 (42%), Gaps = 16/128 (12%)

Query: 321 PTLPIWMMQTMCSPKWQLGLAFLPASVSYLIGTNLFGVLANKMGRWLCSLIGMLVVGTSL 380
           P+  +     +CS +    LA     V  L+G  +FG LA+++GR    ++  L    S 
Sbjct: 117 PSTIVTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSG 176

Query: 381 LCVPLAHNI-----FGLIGPNAGLGLAIGMVDSSM--MPI---------MGHLVDLRHTS 424
            C   A N      F L+   A  G+++  +  ++  MPI         +G++  L    
Sbjct: 177 TCAAFAPNFPIYCAFRLLSGMALAGISLNCMTLNVEWMPIHTRACVGTLIGYVYSLGQFL 236

Query: 425 VYGSVYAI 432
           + G  YA+
Sbjct: 237 LAGVAYAV 244


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.139    0.421 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,435,186
Number of Sequences: 37866
Number of extensions: 862806
Number of successful extensions: 2903
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 28
Number of HSP's that attempted gapping in prelim test: 2845
Number of HSP's gapped (non-prelim): 70
length of query: 525
length of database: 18,247,518
effective HSP length: 107
effective length of query: 418
effective length of database: 14,195,856
effective search space: 5933867808
effective search space used: 5933867808
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.