Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 4506883
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4506883 semenogelin I isoform a preproprotein [Homo sapiens]
(462 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4506883 semenogelin I isoform a preproprotein [Homo sapiens] 938 0.0
gi|38049014 semenogelin I isoform b preproprotein [Homo sapiens] 681 0.0
gi|4506885 semenogelin II precursor [Homo sapiens] 647 0.0
gi|60097902 filaggrin [Homo sapiens] 59 7e-09
gi|171916097 repetin [Homo sapiens] 52 9e-07
gi|62122917 filaggrin family member 2 [Homo sapiens] 51 3e-06
gi|57864582 hornerin [Homo sapiens] 48 2e-05
gi|55749769 CWC22 spliceosome-associated protein homolog [Homo s... 46 8e-05
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 45 1e-04
gi|27734775 hypothetical protein LOC286499 [Homo sapiens] 45 2e-04
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 44 2e-04
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 44 4e-04
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 44 4e-04
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 43 5e-04
gi|4504487 histidine rich calcium binding protein precursor [Hom... 43 5e-04
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 43 7e-04
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 43 7e-04
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 43 7e-04
gi|7657138 golgi integral membrane protein 4 [Homo sapiens] 42 0.001
gi|153251865 hypothetical protein LOC84226 [Homo sapiens] 42 0.001
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 42 0.002
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 41 0.003
gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sap... 40 0.003
gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sap... 40 0.003
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 40 0.004
gi|148746195 trichohyalin [Homo sapiens] 40 0.004
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 40 0.006
gi|87299628 biorientation of chromosomes in cell division 1-like... 39 0.008
gi|62244004 modulator of estrogen induced transcription isoform ... 39 0.008
gi|63176611 modulator of estrogen induced transcription isoform ... 39 0.008
>gi|4506883 semenogelin I isoform a preproprotein [Homo sapiens]
Length = 462
Score = 938 bits (2424), Expect = 0.0
Identities = 462/462 (100%), Positives = 462/462 (100%)
Query: 1 MKPNIIFVLSLLLILEKQAAVMGQKGGSKGRLPSEFSQFPHGQKGQHYSGQKGKQQTESK 60
MKPNIIFVLSLLLILEKQAAVMGQKGGSKGRLPSEFSQFPHGQKGQHYSGQKGKQQTESK
Sbjct: 1 MKPNIIFVLSLLLILEKQAAVMGQKGGSKGRLPSEFSQFPHGQKGQHYSGQKGKQQTESK 60
Query: 61 GSFSIQYTYHVDANDHDQSRKSQQYDLNALHKTTKSQRHLGGSQQLLHNKQEGRDHDKSK 120
GSFSIQYTYHVDANDHDQSRKSQQYDLNALHKTTKSQRHLGGSQQLLHNKQEGRDHDKSK
Sbjct: 61 GSFSIQYTYHVDANDHDQSRKSQQYDLNALHKTTKSQRHLGGSQQLLHNKQEGRDHDKSK 120
Query: 121 GHFHRVVIHHKGGKAHRGTQNPSQDQGNSPSGKGISSQYSNTEERLWVHGLSKEQTSVSG 180
GHFHRVVIHHKGGKAHRGTQNPSQDQGNSPSGKGISSQYSNTEERLWVHGLSKEQTSVSG
Sbjct: 121 GHFHRVVIHHKGGKAHRGTQNPSQDQGNSPSGKGISSQYSNTEERLWVHGLSKEQTSVSG 180
Query: 181 AQKGRKQGGSQSSYVLQTEELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCP 240
AQKGRKQGGSQSSYVLQTEELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCP
Sbjct: 181 AQKGRKQGGSQSSYVLQTEELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCP 240
Query: 241 AHQDKLQHGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHY 300
AHQDKLQHGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHY
Sbjct: 241 AHQDKLQHGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHY 300
Query: 301 GENGVQKDVSQSSIYSQTEEKAQGKSQKQITIPSQEQEHSQKANKISYQSSSTEERRLHY 360
GENGVQKDVSQSSIYSQTEEKAQGKSQKQITIPSQEQEHSQKANKISYQSSSTEERRLHY
Sbjct: 301 GENGVQKDVSQSSIYSQTEEKAQGKSQKQITIPSQEQEHSQKANKISYQSSSTEERRLHY 360
Query: 361 GENGVQKDVSQRSIYSQTEKLVAGKSQIQAPNPKQEPWHGENAKGESGQSTNREQDLLSH 420
GENGVQKDVSQRSIYSQTEKLVAGKSQIQAPNPKQEPWHGENAKGESGQSTNREQDLLSH
Sbjct: 361 GENGVQKDVSQRSIYSQTEKLVAGKSQIQAPNPKQEPWHGENAKGESGQSTNREQDLLSH 420
Query: 421 EQKGRHQHGSHGGLDIVIIEQEDDSDRHLAQHLNNDRNPLFT 462
EQKGRHQHGSHGGLDIVIIEQEDDSDRHLAQHLNNDRNPLFT
Sbjct: 421 EQKGRHQHGSHGGLDIVIIEQEDDSDRHLAQHLNNDRNPLFT 462
>gi|38049014 semenogelin I isoform b preproprotein [Homo sapiens]
Length = 402
Score = 681 bits (1758), Expect = 0.0
Identities = 339/364 (93%), Positives = 345/364 (94%)
Query: 1 MKPNIIFVLSLLLILEKQAAVMGQKGGSKGRLPSEFSQFPHGQKGQHYSGQKGKQQTESK 60
MKPNIIFVLSLLLILEKQAAVMGQKGGSKGRLPSEFSQFPHGQKGQHYSGQKGKQQTESK
Sbjct: 1 MKPNIIFVLSLLLILEKQAAVMGQKGGSKGRLPSEFSQFPHGQKGQHYSGQKGKQQTESK 60
Query: 61 GSFSIQYTYHVDANDHDQSRKSQQYDLNALHKTTKSQRHLGGSQQLLHNKQEGRDHDKSK 120
GSFSIQYTYHVDANDHDQSRKSQQYDLNALHKTTKSQRHLGGSQQLLHNKQEGRDHDKSK
Sbjct: 61 GSFSIQYTYHVDANDHDQSRKSQQYDLNALHKTTKSQRHLGGSQQLLHNKQEGRDHDKSK 120
Query: 121 GHFHRVVIHHKGGKAHRGTQNPSQDQGNSPSGKGISSQYSNTEERLWVHGLSKEQTSVSG 180
GHFHRVVIHHKGGKAHRGTQNPSQDQGNSPSGKGISSQYSNTEERLWVHGLSKEQTSVSG
Sbjct: 121 GHFHRVVIHHKGGKAHRGTQNPSQDQGNSPSGKGISSQYSNTEERLWVHGLSKEQTSVSG 180
Query: 181 AQKGRKQGGSQSSYVLQTEELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCP 240
AQKGRKQGGSQSSYVLQTEELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCP
Sbjct: 181 AQKGRKQGGSQSSYVLQTEELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCP 240
Query: 241 AHQDKLQHGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHY 300
AHQDKLQHGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHY
Sbjct: 241 AHQDKLQHGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHY 300
Query: 301 GENGVQKDVSQSSIYSQTEEKAQGKSQKQITIPSQEQEHSQKANKISYQSSSTEERRLHY 360
GENGVQKDVSQSSIYSQTEEKAQGKSQ Q P QE H + A S QS++ E+ L +
Sbjct: 301 GENGVQKDVSQSSIYSQTEEKAQGKSQIQAPNPKQEPWHGENAKGESGQSTNREQDLLSH 360
Query: 361 GENG 364
+ G
Sbjct: 361 EQKG 364
>gi|4506885 semenogelin II precursor [Homo sapiens]
Length = 582
Score = 647 bits (1670), Expect = 0.0
Identities = 327/436 (75%), Positives = 365/436 (83%)
Query: 1 MKPNIIFVLSLLLILEKQAAVMGQKGGSKGRLPSEFSQFPHGQKGQHYSGQKGKQQTESK 60
MK I+FVLSLLLILEKQAAVMGQKGGSKG+LPS SQFPHGQKGQHY GQK +Q T+SK
Sbjct: 1 MKSIILFVLSLLLILEKQAAVMGQKGGSKGQLPSGSSQFPHGQKGQHYFGQKDQQHTKSK 60
Query: 61 GSFSIQYTYHVDANDHDQSRKSQQYDLNALHKTTKSQRHLGGSQQLLHNKQEGRDHDKSK 120
GSFSIQ+TYHVD NDHD +RKSQQYDLNALHK TKS++HLGGSQQLL+ KQEGRDHDKSK
Sbjct: 61 GSFSIQHTYHVDINDHDWTRKSQQYDLNALHKATKSKQHLGGSQQLLNYKQEGRDHDKSK 120
Query: 121 GHFHRVVIHHKGGKAHRGTQNPSQDQGNSPSGKGISSQYSNTEERLWVHGLSKEQTSVSG 180
GHFH +VIHHKGG+AH GTQNPSQDQGNSPSGKG+SSQ SNTE+RLWVHGLSKEQ S SG
Sbjct: 121 GHFHMIVIHHKGGQAHHGTQNPSQDQGNSPSGKGLSSQCSNTEKRLWVHGLSKEQASASG 180
Query: 181 AQKGRKQGGSQSSYVLQTEELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCP 240
AQKGR QGGSQSSYVLQTEELV NKQQRETKNSHQNKGHYQNVV+VREEHSSK+QTSL P
Sbjct: 181 AQKGRTQGGSQSSYVLQTEELVVNKQQRETKNSHQNKGHYQNVVDVREEHSSKLQTSLHP 240
Query: 241 AHQDKLQHGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHY 300
AHQD+LQHG KDIF+TQDELLVYNKNQHQTKNL+QDQ+HGRKA+KISY SS TEER+LH+
Sbjct: 241 AHQDRLQHGPKDIFTTQDELLVYNKNQHQTKNLSQDQEHGRKAHKISYPSSRTEERQLHH 300
Query: 301 GENGVQKDVSQSSIYSQTEEKAQGKSQKQITIPSQEQEHSQKANKISYQSSSTEERRLHY 360
GE VQKDVS+ SI QTEEK GKSQ Q+TI SQ+QEH K NKISYQSSSTEER L+
Sbjct: 301 GEKSVQKDVSKGSISIQTEEKIHGKSQNQVTIHSQDQEHGHKENKISYQSSSTEERHLNC 360
Query: 361 GENGVQKDVSQRSIYSQTEKLVAGKSQIQAPNPKQEPWHGENAKGESGQSTNREQDLLSH 420
GE G+QK VS+ SI QTE+ + GKSQ Q P Q +G S QS++ E+ L+
Sbjct: 361 GEKGIQKGVSKGSISIQTEEQIHGKSQNQVRIPSQAQEYGHKENKISYQSSSTEERRLNS 420
Query: 421 EQKGRHQHGSHGGLDI 436
+K + S G + I
Sbjct: 421 GEKDVQKGVSKGSISI 436
Score = 288 bits (738), Expect = 6e-78
Identities = 189/447 (42%), Positives = 244/447 (54%), Gaps = 26/447 (5%)
Query: 25 KGGSKGRLPSEFSQFPHGQKGQHYSG---QKGKQQTESKGSFSIQYTYHVDANDHDQSRK 81
KG S +E + HG + S QKG+ Q S+ S+ +Q V +++
Sbjct: 153 KGLSSQCSNTEKRLWVHGLSKEQASASGAQKGRTQGGSQSSYVLQTEELVVNKQQRETKN 212
Query: 82 SQQYDLNALHKTTKSQRHLGGSQQLLHNKQEGRDHDKSKGHF---HRVVIHHKGGKAHRG 138
S Q + + + H Q LH + R K F +++++K
Sbjct: 213 SHQNKGHYQNVVDVREEHSSKLQTSLHPAHQDRLQHGPKDIFTTQDELLVYNKN---QHQ 269
Query: 139 TQNPSQDQGNSPSGKGISSQYSNTEERLWVHGLSKEQTSVSGAQKGRKQGGSQSSYVLQT 198
T+N SQDQ + IS S TEER HG Q VS + S +QT
Sbjct: 270 TKNLSQDQEHGRKAHKISYPSSRTEERQLHHGEKSVQKDVS-----------KGSISIQT 318
Query: 199 EELVANKQQRETK--NSHQNKGHYQNVVEVREEHSSKVQTSLCPAHQDKLQHG-SKDIFS 255
EE + K Q + + Q GH +N + + SS + + +Q G SK S
Sbjct: 319 EEKIHGKSQNQVTIHSQDQEHGHKENKISYQ---SSSTEERHLNCGEKGIQKGVSKGSIS 375
Query: 256 TQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHYGENGVQKDVSQSSIY 315
Q E ++ K+Q+Q + +Q Q++G K NKISYQSSSTEERRL+ GE VQK VS+ SI
Sbjct: 376 IQTEEQIHGKSQNQVRIPSQAQEYGHKENKISYQSSSTEERRLNSGEKDVQKGVSKGSIS 435
Query: 316 SQTEEKAQGKSQKQITIPSQEQEHSQKANKISYQSSSTEERRLHYGENGVQKDVSQRSIY 375
QTEEK GKSQ Q+TIPSQ+QEH K NK+SYQSSSTEERRL+YG QKDVSQ SI
Sbjct: 436 IQTEEKIHGKSQNQVTIPSQDQEHGHKENKMSYQSSSTEERRLNYGGKSTQKDVSQSSIS 495
Query: 376 SQTEKLVAGKSQIQAPNPKQEPWHGENAKGESGQSTNREQDLLSHEQKGRHQHGSHGGLD 435
Q EKLV GKSQIQ PNP Q+ W G+NAKG+SGQS + +QDLLSHEQKGR++ S +
Sbjct: 496 FQIEKLVEGKSQIQTPNPNQDQWSGQNAKGKSGQSADSKQDLLSHEQKGRYKQESSESHN 555
Query: 436 IVIIEQEDDSDRHLAQHLNNDRNPLFT 462
IVI E E D HL Q N DRNP+ T
Sbjct: 556 IVITEHEVAQDDHLTQQYNEDRNPIST 582
>gi|60097902 filaggrin [Homo sapiens]
Length = 4061
Score = 59.3 bits (142), Expect = 7e-09
Identities = 113/472 (23%), Positives = 181/472 (38%), Gaps = 68/472 (14%)
Query: 17 KQAAVMGQKG--GSKGRLPSEF----------SQFPHGQKGQHYS-------GQKGKQQT 57
+ ++V+G G GS G S+ S HGQ G H GQ G++
Sbjct: 1701 QDSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVSAHGQAGPHQQSHQESTRGQSGERSG 1760
Query: 58 ESKGSFSIQYTYHVDAND-HDQSRKSQQYDLNALHKTTK-SQRHLGGSQQLLHNKQEGRD 115
S GSF Q + H + H ++ S + H+ + S RH QEG+D
Sbjct: 1761 RS-GSFLYQVSTHEQSESAHGRTGPSTGGRQRSRHEQARDSSRHSAS--------QEGQD 1811
Query: 116 HDKSKGHFHRVVIHHKGGKAHRGTQNPSQDQGNSPSG-KGISSQYSNTEERLWVHGLSKE 174
+GH G + G Q +Q SG G ++ ++ER V
Sbjct: 1812 --TIRGH---------PGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQERSDVSRGQSG 1860
Query: 175 QTSVSGAQKGRKQGGSQSSYVLQTEELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKV 234
SVS + KQ G S + + A+ + +++S +G R + SS
Sbjct: 1861 SRSVSRQTRNEKQSGDGSRHS-GSRHHEASSRADSSRHSQVGQGQSSGPRTSRNQGSSVS 1919
Query: 235 QTSLCPAHQDKLQHGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTE 294
Q S H + + S S L Q + + + H +A + + S+
Sbjct: 1920 QDSDSQGHSEDSERWSG---SASRNHLGSAWEQSRDGSRHPGSHHEDRAGH-GHSADSSR 1975
Query: 295 ERRLHYGENGVQKDVSQSSIYSQTEEKAQGKSQKQITIPSQEQEHSQKANKISYQSSSTE 354
+ + E+ + + S +++ + S Q+ Q + S+ + Q+SS
Sbjct: 1976 QSGTRHTESSSRGQAASSHEQARSSAGERHGSHHQL----QSADSSRHSGIGHGQASSAV 2031
Query: 355 ERRLHYGENGVQKDVSQ-RSIYSQTEKLVA-GKSQIQAPNPKQEPWHGENAKGESGQSTN 412
H G +G Q S+ S S T+ + A GK+ P Q+ H E+A+G+SG+S+
Sbjct: 2032 RDSGHRGYSGSQASDSEGHSEDSDTQSVSAQGKA-----GPHQQS-HKESARGQSGESSG 2085
Query: 413 REQDLL----SHEQKGRHQHG----SHGGLDIVIIEQEDDSDRHLAQHLNND 456
R L +HEQ HG S GG +Q DS RH A D
Sbjct: 2086 RSGSFLYQVSTHEQ-SESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEGQD 2136
Score = 55.8 bits (133), Expect = 8e-08
Identities = 89/429 (20%), Positives = 162/429 (37%), Gaps = 70/429 (16%)
Query: 41 HGQKGQHYSGQKGKQQTESKGSFSIQYTYHVDANDHDQSRKSQQYDLNALHKTTKSQRHL 100
H Q GQ S +G + + + GS ++ D++ S S+++ +A S+ H
Sbjct: 2546 HSQVGQGQS--EGPRTSRNWGS-----SFSQDSDSQGHSEDSERWSGSA------SRNHH 2592
Query: 101 GGSQ-QLLHNKQEGRDHDKSK-GHFHRVVIHHKGGKAHRGTQNPSQ-----DQGNSPSGK 153
G +Q QL + R H + + GH H + G H T + Q +Q S +G+
Sbjct: 2593 GSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGE 2652
Query: 154 GISSQYSNTEERLWVHGLSKEQTS----------VSGAQKGRKQGGSQSSYVLQTEELVA 203
S + + + G+ Q S SG+Q +G S+ S T+ + A
Sbjct: 2653 RHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDS---DTQSVSA 2709
Query: 204 NKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCPAHQDKLQHG-----SKDIFSTQD 258
+ Q + SHQ ++ HS + Q + HG ++ ++
Sbjct: 2710 HGQAGSHQQSHQESARGRS--GETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRH 2767
Query: 259 ELLVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHYGENGVQKDVSQSSIYSQT 318
E + ++H QD G + SS R+ ++ E+ V S +S T
Sbjct: 2768 EQ-AQDSSRHSASQDGQDTIRG-------HPGSSRGGRQGYHHEHSVDSSGHSGSHHSHT 2819
Query: 319 EEKAQGKSQKQITIPSQEQEHSQKANKISYQSSSTEERRLHYG----ENGVQKDVSQRSI 374
+QG+S S+ Q S+ A++ + + + H G E D+S+ S
Sbjct: 2820 T--SQGRSDA-----SRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEASTHADISRHSQ 2872
Query: 375 YSQTEKLVAGKSQIQAPNPKQ-----------EPWHGENAKGESGQSTNREQDLLSHEQK 423
Q + + +S+ Q + Q E W G ++ G + + +D H +
Sbjct: 2873 AVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRS 2932
Query: 424 GRHQHGSHG 432
+ HG
Sbjct: 2933 HQEDRAGHG 2941
Score = 55.5 bits (132), Expect = 1e-07
Identities = 99/441 (22%), Positives = 162/441 (36%), Gaps = 67/441 (15%)
Query: 41 HGQKGQHYSGQKGKQQTESKGSFSIQYTYHVDANDHDQSRKSQQYDLNALHKTTKSQRHL 100
HGQ G H + + S G ++ + H+QS + H T++
Sbjct: 1089 HGQDGPHQQSHQESARDWSGGRSGRSGSFIYQVSTHEQSESA--------HGRTRTST-- 1138
Query: 101 GGSQQLLHNKQEGRDHDKSKGHFHRVVIHHKGGKAHRGTQNPSQDQGNSPSGKGISSQYS 160
G +Q H++Q S + I G G Q +Q SG S +S
Sbjct: 1139 -GRRQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHS-GSHHS 1196
Query: 161 NTEERLWVHGLSKEQTSVSGAQKGRKQGGSQSSYVLQTEELVANKQQRETKNSHQNKGHY 220
+T TS + Q GS+S+ ++ + R + + H +
Sbjct: 1197 HT-------------TSQGRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASW 1243
Query: 221 QNVV---EVREEHSSKVQTSLCPAHQDKL--QHGSKDIFSTQDELLVYNKNQHQTKNLNQ 275
+ +V +E SS +TS HQ Q + S E L + +++ + +
Sbjct: 1244 ADSSRHSQVGQEQSSGSRTS---RHQGSSVSQDSDSERHSDDSERLSGSASRNHHGSSRE 1300
Query: 276 DQQHGRKANKISYQSSSTEERRLHYGENGVQKDVSQSSIYSQTEEKAQGKS----QKQIT 331
+ G + + E+R H G D S+ S TE + G++ ++ +
Sbjct: 1301 QSRDGSR-----HPGFHQEDRASH----GHSADSSRQSGTHHTESSSHGQAVSSHEQARS 1351
Query: 332 IPSQEQ--EHSQKANKISY------QSSSTEERRLHYGENGVQKDVSQRSIYSQTEKLVA 383
P + H Q A+ + Q+SS H G +G Q S+ + V+
Sbjct: 1352 SPGERHGSRHQQSADSSRHSGIGHRQASSAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVS 1411
Query: 384 GKSQIQAPNPKQEPWHGENAKGESGQSTNREQDLL----SHEQKGRHQHG----SHGGLD 435
Q P Q+ H E+A+G+SG+S+ R + L SHEQ HG S GG
Sbjct: 1412 AHGQA---GPHQQS-HKESARGQSGESSGRSRSFLYQVSSHEQ-SESTHGQTAPSTGGRQ 1466
Query: 436 IVIIEQEDDSDRHLAQHLNND 456
EQ +S RH A D
Sbjct: 1467 GSRHEQARNSSRHSASQDGQD 1487
Score = 53.9 bits (128), Expect = 3e-07
Identities = 98/449 (21%), Positives = 158/449 (35%), Gaps = 83/449 (18%)
Query: 41 HGQKGQHYSGQKGKQQTESKGSFSIQYTYHVDANDHDQSRKSQQYDLNALHKTTKSQRHL 100
HGQ G H + + S + ++ + H+QS S + T S R
Sbjct: 3034 HGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGW-------TGPSTRGR 3086
Query: 101 GGSQQLLHNKQEGRDHDKSKGHFHRVVIHHKGGKAHRGTQNPSQDQGNSPSGKGISSQYS 160
GS+ Q+ H S+ + + I G + G Q + SG S +S
Sbjct: 3087 QGSRH--EQAQDSSRHSASQ--YGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHS-GSHHS 3141
Query: 161 NTEERLWVHGLSKEQTSVSGAQKGRKQGGSQS-SYVLQTEELVANKQQRETKNSHQNKGH 219
+T TS + R Q GS+S S + EE + + H+ H
Sbjct: 3142 HT-------------TSQGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEASTH 3188
Query: 220 -----YQNVVEVREEHSSKVQTSLCPAHQDKLQHGSKDIFSTQDELLVYNKNQHQTKNLN 274
+ V+ + E S + + QD G S E + +++ ++
Sbjct: 3189 ADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGH----SEDSERWSGSASRNHRGSVQ 3244
Query: 275 QDQQHGRKANKISYQSSSTEERRLHYGENGVQKDVSQSSIYSQTEEKAQGKS----QKQI 330
+ +HG + + S E+R H G D S+ S E + G++ ++
Sbjct: 3245 EQSRHGSR-----HPRSHHEDRAGH----GHSADRSRQSGTRHAETSSGGQAASSHEQAR 3295
Query: 331 TIPSQEQ--EHSQKANKISY------QSSSTEERRLHYGENGVQKDVSQRSIYSQTEKLV 382
+ P + H Q A+ + Q+SS H+G +G Q S+ + V
Sbjct: 3296 SSPGERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGHSEESDTQSV 3355
Query: 383 AGKSQIQAPNPKQEPWHGENAKGESGQSTNREQDLL----SHEQK-----------GRHQ 427
+G Q P Q+ H E+A+ SG + R L +HEQ GR Q
Sbjct: 3356 SGHGQ---AGPHQQS-HQESARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRRQ 3411
Query: 428 HGSHGGLDIVIIEQEDDSDRHLAQHLNND 456
H EQ DS RH A D
Sbjct: 3412 GSHH--------EQARDSSRHSASQEGQD 3432
Score = 53.1 bits (126), Expect = 5e-07
Identities = 100/477 (20%), Positives = 160/477 (33%), Gaps = 48/477 (10%)
Query: 16 EKQAAVMGQKGGSKGRLPSEFSQFP---HGQ-----KGQHYSGQKGKQQTESKGSFSIQY 67
E+ + G++ GS + ++ S+ HGQ + + G G Q ++S+G
Sbjct: 2320 EQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSD 2379
Query: 68 TYHVDANDHDQSRKSQQYDLNALHKTTKSQRHLGGS---QQLLHNKQEGRDHDKSKGHFH 124
T V A H Q+ QQ + + + GS Q H + E
Sbjct: 2380 TQSVSA--HGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGG 2437
Query: 125 RVVIHHKGGK--AHRGTQNPSQD----QGNSPSGKGISSQYSNTEERLWVHGLSKEQTSV 178
R HHK + + T QD S SG S Y +R G T+
Sbjct: 2438 RQGSHHKQARDSSRHSTSQEGQDTIHGHPGSSSGGRQGSHYEQLVDRSGHSGSHHSHTTS 2497
Query: 179 SGAQKGRKQGGSQSSYVLQTEELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSL 238
G S QT N +Q + H H++ S+V
Sbjct: 2498 QGRSDASHGHSGSRSASRQTR----NDEQSGDGSRHSGSRHHEASSRADSSGHSQVGQGQ 2553
Query: 239 CPAHQDKLQHGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEERRL 298
+ GS FS + ++++ + HG ++ S +
Sbjct: 2554 SEGPRTSRNWGSS--FSQDSDSQGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQE 2611
Query: 299 HYGENGVQKDVSQSSIYSQTEEKAQGK---SQKQITIPSQEQE---HSQKANKISY---- 348
+G D S+ S T+ + G+ S +Q + E+ H Q A+ +
Sbjct: 2612 DRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIG 2671
Query: 349 --QSSSTEERRLHYGENGVQKDVSQRSIYSQTEKLVAGKSQIQAPNPKQEPWHGENAKGE 406
Q+SS H G +G Q S +S+ + + QA + +Q H E+A+G
Sbjct: 2672 HGQASSAVRDSGHRGYSGSQ--ASDNEGHSEDSDTQSVSAHGQAGSHQQS--HQESARGR 2727
Query: 407 SGQSTNREQDLLSHEQKGRHQHGSHG-------GLDIVIIEQEDDSDRHLAQHLNND 456
SG+++ L SHG G EQ DS RH A D
Sbjct: 2728 SGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQDGQD 2784
Score = 49.7 bits (117), Expect = 6e-06
Identities = 93/445 (20%), Positives = 170/445 (38%), Gaps = 47/445 (10%)
Query: 18 QAAVMGQKGGSKGRLPS---EFSQFPHGQKGQHYSGQKGKQQTESKGSFSIQYTYHVDAN 74
Q + G G S+G E S G G H+S + ++++ S +
Sbjct: 3107 QDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTR 3166
Query: 75 DHDQSRKSQQYDLNALHKTT-------KSQRHLGGSQQLLHNKQEGRD-HDKSKGHFHRV 126
+ +QS S ++ ++ H+ + SQ G S+ ++++G S H
Sbjct: 3167 NEEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSE 3226
Query: 127 VIHHKGGKAHRGTQNPSQDQGNSPSGKGISSQYSNTEERLWVHGLSKEQTSVSGAQKGRK 186
G A R + Q+Q S G S+ E+R HG S +++ SG +
Sbjct: 3227 DSERWSGSASRNHRGSVQEQ----SRHGSRHPRSHHEDRAG-HGHSADRSRQSGTRHAET 3281
Query: 187 QGGSQSSYVLQTEELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCPAHQDKL 246
G Q++ +++Q R + H Q+ R HS + A +D
Sbjct: 3282 SSGGQAA--------SSHEQARSSPGERHGSRHQQSADSSR--HSGIPRGQASSAVRDSR 3331
Query: 247 QHGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHYGENGVQ 306
GS ++ E + + T++++ Q G ++ S+Q S+ + G +G
Sbjct: 3332 HWGSSGSQASDSE---GHSEESDTQSVSGHGQAG--PHQQSHQESARDRSGGRSGRSG-- 3384
Query: 307 KDVSQSSIYSQTEEKAQGKSQKQITIPSQEQEHSQKANKISYQSSSTEERRLHYGENGVQ 366
+ Q S + Q+ E A G++ + + ++ H ++A S S+S E + G G
Sbjct: 3385 SFLYQVSTHEQS-ESAHGRT--RTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSS 3441
Query: 367 KDVSQRSIYSQTEKLVAGKSQIQAPNPKQEPWHGENAKGESGQSTNREQDLLSHEQKG-- 424
+ Q S Y Q+ + Q + ++G+SG S + + + EQ G
Sbjct: 3442 RRGRQGSHYEQSVDRSGHSGSHHSHTTSQ--GRSDASRGQSG-SRSASRQTRNDEQSGDG 3498
Query: 425 -RHQHGSHGGLDIVIIEQEDDSDRH 448
RH H + DS RH
Sbjct: 3499 SRHSWSHHHE-----ASTQADSSRH 3518
Score = 48.9 bits (115), Expect = 1e-05
Identities = 94/452 (20%), Positives = 148/452 (32%), Gaps = 76/452 (16%)
Query: 18 QAAVMGQKGGSKGRLPSEFSQFPHGQKGQHYSGQKGKQQTESKGSFSIQYTYHVDANDHD 77
Q + G+ G GR S Q ++ G+ G +GS +H A D
Sbjct: 451 QESTRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGS------HHEQARDSS 504
Query: 78 QSRKSQQYDLNALHKTTKSQRHLGGSQQLLHNKQEGRDHDKSKGHFHRV------VIHHK 131
+ SQ+ + + S R GG Q H + R H H H +
Sbjct: 505 RHSASQEGQ-DTIRGHPGSSR--GGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQ 561
Query: 132 GGKAHRGTQNPSQDQGNSPSGKGISSQYSNTEERLWVHGLSKEQTSVSGAQKGRKQGGSQ 191
G Q +++Q SG G S E S+ G G + +Q
Sbjct: 562 SGSRSASRQTRNEEQ----SGDGTRHSGSRHHEASSQADSSRHSQVGQGQSSGPRTSRNQ 617
Query: 192 SSYVLQTEELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCPAHQDKLQHGSK 251
S V Q + + + E + ++ H+ + E + S ++ H+D+ HG
Sbjct: 618 GSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQSRDGSRHPRSH----HEDRAGHGHS 673
Query: 252 DIFSTQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHYGENGVQKDVSQ 311
S + T+N + Q +SS E+ R GE + Q
Sbjct: 674 ADSSRKS-------GTRHTQNSSSGQA-----------ASSHEQARSSAGERHGSRHQLQ 715
Query: 312 SSIYSQTEEKAQGKSQKQITIPSQEQEHSQKANKISYQSSSTEERRLHYGENGVQKDVSQ 371
S+ S+ G Q+SS H G +G Q S+
Sbjct: 716 SADSSRHSGTGHG------------------------QASSAVRDSGHRGSSGSQATDSE 751
Query: 372 RSIYSQTEKLVAGKSQIQAPNPKQEPWHGENAKGESGQSTNREQDLLSHEQKGRHQHGSH 431
+ V+G Q A + +Q H E+A+ SG+ + R L + SH
Sbjct: 752 GHSEDSDTQSVSGHGQ--AGHHQQS--HQESARDRSGERSRRSGSFLYQVSTHKQSESSH 807
Query: 432 G--GLDIVI-----IEQEDDSDRHLAQHLNND 456
G G + EQ D+ RH A D
Sbjct: 808 GWTGPSTGVRQGSHHEQARDNSRHSASQDGQD 839
Score = 47.0 bits (110), Expect = 4e-05
Identities = 87/458 (18%), Positives = 145/458 (31%), Gaps = 73/458 (15%)
Query: 23 GQKGGSKGRLPSEFSQFPHGQKGQH-YSGQKGKQQTESKGSFSIQYTYHVDANDHDQSRK 81
G++ GS + S+ Q+GQ G G + +GS Y VD + H S
Sbjct: 3408 GRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQGS---HYEQSVDRSGHSGSHH 3464
Query: 82 SQQYDLNALHKTT--KSQRHLGGSQQLLHNKQEGRDHDKSKGHFHRVVIHH--------- 130
S H T+ +S G S ++Q D G H HH
Sbjct: 3465 S--------HTTSQGRSDASRGQSGSRSASRQTRNDEQSGDGSRHSWSHHHEASTQADSS 3516
Query: 131 ---KGGKAHRGTQNPSQDQGNSPSGKGISSQYSNTEERLWV------------------- 168
+ G+ S++QG+S S S +S ER W
Sbjct: 3517 RHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSER-WSGSASRNHRGSAQEQSRDGS 3575
Query: 169 ------------HGLSKEQTSVSGAQKGRKQGGSQSSYVLQT------EELVANKQQRET 210
HG S E + SG G Q++ + E ++ QQ
Sbjct: 3576 RHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSAD 3635
Query: 211 KNSHQNKGHYQNVVEVRE---EHSSKVQTSLCPAHQDKLQHGSKDIFSTQDELLVYNKNQ 267
+ H GH Q VR+ SS Q S H + S ++
Sbjct: 3636 SSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGP----HQQS 3691
Query: 268 HQTKNLNQDQQHGRKANKISYQSSSTEERRLHYGENGVQKDVSQSSIYSQTEEKAQGKSQ 327
HQ + ++ YQ S+ E+ +G G Q S + Q + ++ +
Sbjct: 3692 HQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSAS 3751
Query: 328 KQITIPSQEQEHSQKANKISYQSSSTEERRLHYGENGVQKDVSQRSIYSQTEKLVAGKSQ 387
++ + S++ + + +R H G + RS S + +S
Sbjct: 3752 QEGQDTIRGHPGSRRGGRQGSYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQS--GSRSA 3809
Query: 388 IQAPNPKQEPWHGENAKGESGQSTNREQDLLSHEQKGR 425
+ +++ G G + + D H Q G+
Sbjct: 3810 SRETRNEEQSGDGSRHSGSRHHEASTQADSSRHSQSGQ 3847
Score = 46.6 bits (109), Expect = 5e-05
Identities = 98/437 (22%), Positives = 151/437 (34%), Gaps = 89/437 (20%)
Query: 41 HGQKGQHYSGQKGKQQTESKGSFSIQYTYHVDANDHDQSRKSQQYDLNALHK--TTKSQR 98
HG S Q G + TES A+ H+Q+R S + H+ + S R
Sbjct: 1967 HGHSADS-SRQSGTRHTESSSRGQA-------ASSHEQARSSAGERHGSHHQLQSADSSR 2018
Query: 99 HLG-GSQQLL-------HNKQEGRDHDKSKGHFHRVVIHHKGGKAHRGTQNPSQDQGNSP 150
H G G Q H G S+GH + +G P Q Q +
Sbjct: 2019 HSGIGHGQASSAVRDSGHRGYSGSQASDSEGHSED---SDTQSVSAQGKAGPHQ-QSHKE 2074
Query: 151 SGKGISSQYSNTEERLWVHGLSKEQTSVSGAQKGRKQGGSQSSYVLQTEEL---VANKQQ 207
S +G S + S + EQ+ + Q GG Q S+ Q ++ A+++
Sbjct: 2075 SARGQSGESSGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEG 2134
Query: 208 RETKNSHQ------NKGHYQNVVEVREEHSSKVQTSLCPAHQDKLQHGSKDIFSTQDELL 261
++T H +G +Q R HS H G D
Sbjct: 2135 QDTIRGHPGPSRGGRQGSHQEQSVDRSGHSGS-------HHSHTTSQGRSD--------- 2178
Query: 262 VYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHYG----ENGVQKDVSQSSIYSQ 317
++ Q R A++ +Y + + H G E D S+ S+ Q
Sbjct: 2179 -----------ASRGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQ 2227
Query: 318 TEEKAQGKSQKQITIPSQEQE---HSQKANKISYQSSSTEERRLHYGENGVQKDVSQRSI 374
+ S+ + + SQ+ + HS+ + + S +S R H+G Q R
Sbjct: 2228 GQSSGPRTSRPRGSSVSQDSDSEGHSEDSERRSGSAS-----RNHHGSAQEQSRDGSRHP 2282
Query: 375 YSQTEKLVAGKSQIQAPNPKQEPWHGENAKGESGQSTNREQDLLSHEQ---KGRHQHGSH 431
S E AG + + H EN+ G GQ+ + SHEQ +HGSH
Sbjct: 2283 RSHHEDR-AGHGHSAESSRQSGTHHAENSSG--GQAAS------SHEQARSSAGERHGSH 2333
Query: 432 GGLDIVIIEQEDDSDRH 448
+Q DS RH
Sbjct: 2334 H-------QQSADSSRH 2343
Score = 45.1 bits (105), Expect = 1e-04
Identities = 84/442 (19%), Positives = 152/442 (34%), Gaps = 53/442 (11%)
Query: 41 HGQKGQHYSGQ-----KGKQQTESKGSFSIQYTYHVDANDHDQSRKSQQYDLNALHKTTK 95
H + + +SG +G Q +S+ ++H D H S +S + T
Sbjct: 3548 HSEDSERWSGSASRNHRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQS-----GTHH 3602
Query: 96 SQRHLGGSQQLLHNKQEGRDHDKSKGHFHRVVIHHK-GGKAHRGTQNPSQDQGN-SPSGK 153
++ GG H + ++ H + + G H + +D G+ SG
Sbjct: 3603 AENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGS 3662
Query: 154 GISSQYSNTEER----LWVHGLS-----KEQTSVSGAQKGRKQGGSQSSYVLQTEELVAN 204
S ++E+ + HG + Q S G GR Y + T E +
Sbjct: 3663 QASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSES 3722
Query: 205 KQQRETKNSHQNKGHYQNVVEVREEHSSKVQ-TSLCPAHQDKLQHGSKDIFSTQDELLVY 263
R ++ +G HS+ + H + G + + Q
Sbjct: 3723 AHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSRRGGRQGSYHEQSVDRSG 3782
Query: 264 NKNQHQTKNLNQ---DQQHGRKANKISYQSSSTEER----RLHYG----ENGVQKDVSQS 312
+ H + +Q D HG+ ++ + + + EE+ H G E Q D S+
Sbjct: 3783 HSGSHHSHTTSQGRSDASHGQSGSRSASRETRNEEQSGDGSRHSGSRHHEASTQADSSRH 3842
Query: 313 SIYSQTEEKAQGKSQKQITIPSQEQEHSQKANKISYQSSSTEERRLHYGENGVQKDVSQR 372
S Q E +S++Q + SQ+ + S+ + S + S + R H +D S+
Sbjct: 3843 SQSGQGESAGSRRSRRQGSSVSQDSD-SEAYPEDSERRSESASRNHHGSSREQSRDGSRH 3901
Query: 373 --SIYSQTEKLVAGKSQIQAPNPKQEPWHGENAKGES-------------GQSTNREQDL 417
S + T V + +E H + +S S+ Q
Sbjct: 3902 PGSSHRDTASHVQSSPVQSDSSTAKEHGHFSSLSQDSAYHSGIQSRGSPHSSSSYHYQSE 3961
Query: 418 LSHEQKGRH----QHGSHGGLD 435
+ QKG+ +HGS+G D
Sbjct: 3962 GTERQKGQSGLVWRHGSYGSAD 3983
Score = 44.7 bits (104), Expect = 2e-04
Identities = 78/381 (20%), Positives = 128/381 (33%), Gaps = 61/381 (16%)
Query: 91 HKTTKSQRHLGGS-QQLLHNKQEGRDHDKSKG-HFHRVVIHHKGGKAH-----RGTQNPS 143
H + S+ H G + +Q + R HD+ + H H + G H RG S
Sbjct: 313 HSGSASRNHHGSAWEQSRDGSRHPRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTASS 372
Query: 144 QDQGNSPSGK--GISSQYSNTEERLWVHGLSKEQTSVS--------GAQKGRKQGGSQSS 193
+Q S G+ G Q S R G + ++VS G+Q +G S++S
Sbjct: 373 HEQARSSPGERHGSGHQQSADSSRHSATGRGQASSAVSDRGHRGSSGSQASDSEGHSENS 432
Query: 194 YVLQTEELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCPAHQDKLQHGSKDI 253
T+ + + + + SHQ ++ SS Q S Q HG
Sbjct: 433 ---DTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVST--HEQPDSAHGRTG- 486
Query: 254 FSTQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHYGENGVQKDVSQSS 313
T + H +A S S+S E + G G + Q S
Sbjct: 487 ----------------TSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGS 530
Query: 314 IYSQTEEKAQGKSQKQITIPSQ---EQEHSQKANKISYQSSSTEERR----LHYG----E 362
+ Q+ ++ SQ + H Q ++ + + + EE+ H G E
Sbjct: 531 HHEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHE 590
Query: 363 NGVQKDVSQRSIYSQTEKL-----------VAGKSQIQAPNPKQEPWHGENAKGESGQST 411
Q D S+ S Q + V+ S Q + E W G ++ G +
Sbjct: 591 ASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQ 650
Query: 412 NREQDLLSHEQKGRHQHGSHG 432
+ +D H + HG
Sbjct: 651 EQSRDGSRHPRSHHEDRAGHG 671
Score = 40.8 bits (94), Expect = 0.003
Identities = 91/440 (20%), Positives = 148/440 (33%), Gaps = 55/440 (12%)
Query: 41 HGQKGQHYSGQKGKQQTESKGSFSIQYTYHVDANDHDQSRKSQQYDLNALHKTTKSQRHL 100
H + + +SG + S S + H ++ D++ D + T +Q
Sbjct: 630 HSEDSERWSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQNSS 689
Query: 101 GGSQQLLHNKQEGRDHDKSKGHFHRVVIHHKGGKAHRGTQNPSQDQGNSPSGKGISSQYS 160
G H + ++ H R + H GT + SG SS
Sbjct: 690 SGQAASSHEQARSSAGER---HGSRHQLQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQ 746
Query: 161 NTEERLWVHGLSKEQTSVSG-AQKGRKQGGSQSSYVLQTEE--------LVANKQQRETK 211
T+ H + SVSG Q G Q Q S ++ E L ++++
Sbjct: 747 ATDSE--GHSEDSDTQSVSGHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSE 804
Query: 212 NSH----------QNKGHYQNVVEVREEHSSKVQTSLC--PAHQDKLQHGSKDIFSTQDE 259
+SH Q H Q R S Q ++ P + + GS S
Sbjct: 805 SSHGWTGPSTGVRQGSHHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVDRS 864
Query: 260 LLVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEER----RLHYG----ENGVQKDVSQ 311
+ + H T D G+ ++ + +++ EE+ H G E D+S+
Sbjct: 865 GHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEASSHADISR 924
Query: 312 SSIYSQTEEKAQGKSQKQITIPSQEQE---HSQKANKISYQSSSTEERRLHYGENGVQKD 368
S Q + + S++Q + SQ+ + HS+ + + S +S R H G Q
Sbjct: 925 HSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSAS-----RNHRGSAQEQSR 979
Query: 369 VSQRSIYSQTEKLVAGKSQIQAPNPKQEPWHGENAKGESGQSTNREQDLLSHEQKGRHQH 428
R S E + P H E + G GQ+ + SHEQ
Sbjct: 980 HGSRHPRSHHEDRAGHGHSADSSRQSGTP-HAETSSG--GQAAS------SHEQARSSPG 1030
Query: 429 GSHGGLDIVIIEQEDDSDRH 448
HG +Q DS RH
Sbjct: 1031 ERHGSRH----QQSADSSRH 1046
>gi|171916097 repetin [Homo sapiens]
Length = 784
Score = 52.4 bits (124), Expect = 9e-07
Identities = 59/288 (20%), Positives = 114/288 (39%), Gaps = 32/288 (11%)
Query: 172 SKEQTSVSGAQKGRKQGGSQSSYVLQTEELVANKQQRETKNSHQNKGHYQNVVEVREEHS 231
S+++ GAQ + G + + + EE N + + + H Q + R+ H
Sbjct: 99 SQQERGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDSHHGQPERQDRDSHH 158
Query: 232 SKVQTSLCPAHQDKLQHGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQSS 291
+ + +H + + +D Q E + + Q++ +QD G+ K+S++S+
Sbjct: 159 GQSEKQDRDSHHSQPERQDRDSHHNQSERQDKDFSFDQSERQSQDSSSGK---KVSHKST 215
Query: 292 STEER----------------RLHYGEN----GVQKDVSQSSIYSQTEEKAQGKSQKQIT 331
S + + HYG++ + + Q+S ++QT ++ G Q
Sbjct: 216 SGQAKWQGHIFALNRCEKPIQDSHYGQSERHTQQSETLGQASHFNQTNQQKSGSYCGQSE 275
Query: 332 IPSQE---QEHSQKANKISYQSSSTEERRLHYGENGVQKDVSQRSIYSQTEKLVAGKSQI 388
QE + ++ Y + +++ HYG+ Q Q S YSQT++
Sbjct: 276 RLGQELGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQ---GQSSHYSQTDRQGQSSHYS 332
Query: 389 QAPNPKQEPWHGE-NAKGE--SGQSTNREQDLLSHEQKGRHQHGSHGG 433
Q Q +G+ + KG+ TNR+ + Q R SH G
Sbjct: 333 QPDRQGQSSHYGQMDRKGQCYHYDQTNRQGQGSHYSQPNRQGQSSHYG 380
Score = 52.0 bits (123), Expect = 1e-06
Identities = 90/422 (21%), Positives = 146/422 (34%), Gaps = 45/422 (10%)
Query: 23 GQKGGSKGRLPSEFSQFPHGQKGQ--HYSGQKGKQ-------QTESKGSFSIQYTYHVDA 73
G G RL E ++GQ HY GQ +Q QT+ +G S
Sbjct: 268 GSYCGQSERLGQELGCGQTDRQGQSSHY-GQTDRQDQSYHYGQTDRQGQSS-------HY 319
Query: 74 NDHDQSRKSQQYDLNALHKTTKSQRHLGGSQQLLHNKQEGRDHDKSKGHFHRVVIHHKGG 133
+ D+ +S Y + + Q H Q R S H + +G
Sbjct: 320 SQTDRQGQSSHYSQPDRQGQSSHYGQMDRKGQCYHYDQTNRQGQGS----HYSQPNRQGQ 375
Query: 134 KAHRGTQNPSQDQGN---SPSGKGISSQYSNTEERLWVHGLSKEQTSVSGAQKGRKQGGS 190
+H G Q +QDQ + + SS Y TE + S+ G+ G+
Sbjct: 376 SSHYG-QPDTQDQSSHYGQTDRQDQSSHYGQTERQGQSSHYSQMDRQGQGSHYGQTDRQG 434
Query: 191 QSSYVLQTEELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCPAHQDKLQHGS 250
QSS+ Q + N +T Q+ + Q + + H S+ +H K+
Sbjct: 435 QSSHYGQPDRQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQGQSSHYGKIDRQD 494
Query: 251 KDIFSTQDELLVYNKNQHQTKNLNQDQQHG---RKANKISYQSSSTEERRLHYGENGVQK 307
+ Q + + + QT Q +G R+ Y + + HYG+ Q
Sbjct: 495 QSYHYGQPDGQGQSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQSSHYGQTDRQ- 553
Query: 308 DVSQSSIYSQTEEKAQGKSQKQITIPSQEQEHSQKANKISYQSSSTEERRLHY-GENGVQ 366
QSS Y QT+ + Q Q Q ++ I Q+ + + ++ G G +
Sbjct: 554 --GQSSHYGQTDRQGQSYHY------GQTDRQGQSSHYIQSQTGEIQGQNKYFQGTEGTR 605
Query: 367 KDVSQRSIYSQTEKLVAGKSQIQAPNPKQEPWHGENAKGESGQSTNREQDLLSHEQKGRH 426
K S Q+ + +G+ Q P + G+ + Q N Q E H
Sbjct: 606 K----ASYVEQSGR--SGRLSQQTPGQEGYQNQGQGFQSRDSQQ-NGHQVWEPEEDSQHH 658
Query: 427 QH 428
QH
Sbjct: 659 QH 660
>gi|62122917 filaggrin family member 2 [Homo sapiens]
Length = 2391
Score = 50.8 bits (120), Expect = 3e-06
Identities = 98/449 (21%), Positives = 143/449 (31%), Gaps = 44/449 (9%)
Query: 23 GQKGGSKGRLPSEFSQFPHGQKGQHYSGQKGKQQTESKGSFSIQYTYHVDANDHDQSRKS 82
GQ G G+ S Q +GQ G S G Q S + + H + QS
Sbjct: 1059 GQSSGF-GQYESRSRQSSYGQHGSGSSQSSGYGQHGSNSGQTSGFGQHRPGSG--QSSGF 1115
Query: 83 QQYDLNALHKTTKSQRHLGGSQQLLHNKQEGRDHDKSKGHFHRVVIHHKGGKAHRGTQNP 142
QY + + Q G + + E R S G G H P
Sbjct: 1116 GQYGSGSGQSSGFGQHGSGTGKSSGFAQHEYRSGQSSYGQHGTGSSQSSGCGQHESGSGP 1175
Query: 143 SQDQGNSPSGKGISSQYSNTEERLWVHGLSK---EQTSVSGAQKGRKQGGSQS----SYV 195
+ G SG S +S++ + + G S + S SG G QG SQ S V
Sbjct: 1176 TTSFGQHVSG---SDNFSSSGQHISDSGQSTGFGQYGSGSGQSTGLGQGESQQVESGSTV 1232
Query: 196 LQTEELVANKQQRETKNSHQNKGHYQNVVE--VREEHSSKVQTSLCPAHQDKLQHGSKDI 253
+E + T++S +G R SS+ + S H K+ H +
Sbjct: 1233 HGRQETTHGQTINTTRHSQSGQGQSTQTGSRVTRRRRSSQSENSDSEVHS-KVSHRHSEH 1291
Query: 254 FSTQ------DELLVYNKNQHQTKNLNQDQ-QHGRKANKISYQSSSTEERRLHYGENGVQ 306
TQ + Q T D +HG + S Q+ S R + +
Sbjct: 1292 IHTQAGSHYPKSGSTVRRRQGTTHGQRGDTTRHGHSGHGQSTQTGSRTSGRQRFSHS--- 1348
Query: 307 KDVSQSSIYSQTEEKAQGKSQKQITIPSQEQEHSQKANKISYQSSSTEER-RLHYGENGV 365
D + S ++S + SQEQ HSQ ++ S+ ER YG+ G
Sbjct: 1349 -DATDSEVHSGVSHRPH----------SQEQTHSQAGSQHGESESTVHERHETTYGQTGE 1397
Query: 366 QKDVSQRSIYSQTEK--LVAGKSQIQAPNPKQEPWHGENAKGESGQSTNREQDLLSHEQK 423
T++ G+ H + Q Q H +
Sbjct: 1398 ATGHGHSGHGQSTQRGSRTTGRRGSGHSESSDSEVHSGGSHRPQSQEQTHGQAGSQHGES 1457
Query: 424 GRHQHGSHGGLDIVIIEQEDDSDRHLAQH 452
G HG HG Q D+ RH H
Sbjct: 1458 GSTVHGRHG----TTHGQTGDTTRHAHYH 1482
Score = 37.4 bits (85), Expect = 0.029
Identities = 76/439 (17%), Positives = 149/439 (33%), Gaps = 49/439 (11%)
Query: 36 FSQFPHGQKGQHYSGQKGKQQTESKGSF-SIQYTYH---VDANDHDQSRKSQQYDLNALH 91
F Q+ G GQ QQ ES + Q T H ++ H QS + Q +
Sbjct: 1205 FGQYGSGSGQSTGLGQGESQQVESGSTVHGRQETTHGQTINTTRHSQSGQGQSTQTGSRV 1264
Query: 92 KTTKSQRHLGGSQQLLHNKQEGRD----HDKSKGHFHRV--VIHHKGGKAHRGTQNPSQD 145
+ S +H+K R H ++ H+ + + + G H G + +
Sbjct: 1265 TRRRRSSQSENSDSEVHSKVSHRHSEHIHTQAGSHYPKSGSTVRRRQGTTH-GQRGDTTR 1323
Query: 146 QGNSPSGKGISSQYSNTEERLWVHGLSKEQTSVSGA-------QKGRKQGGSQSSYVLQT 198
G+S G+ + + + + H + + SG ++ Q GSQ ++
Sbjct: 1324 HGHSGHGQSTQTGSRTSGRQRFSHSDATDSEVHSGVSHRPHSQEQTHSQAGSQHG---ES 1380
Query: 199 EELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCPAHQD----KLQHGSKDIF 254
E V + + + + GH + + S+ H + ++ G
Sbjct: 1381 ESTVHERHETTYGQTGEATGHGHSGHGQSTQRGSRTTGRRGSGHSESSDSEVHSGGSHRP 1440
Query: 255 STQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHYGENGVQ-------- 306
+Q++ +QH HGR +T H+G++ +
Sbjct: 1441 QSQEQTHGQAGSQHGESG---STVHGRHGTTHGQTGDTTRHAHYHHGKSTQRGSSTTGRR 1497
Query: 307 ----KDVSQSSIYSQTEEKAQGKSQKQITIPSQEQEHS-QKANKISYQSSSTEERRLHYG 361
+ S S ++S G + Q E E ++I++ + R + G
Sbjct: 1498 GSGHSESSDSEVHSGGSHTHSGHTHGQSGSQHGESESIIHDRHRITHGQTGDTTRHSYSG 1557
Query: 362 -----ENGVQKDVSQRSIYSQTEKLVAGKSQIQAPNPKQEPWHGENAKGESGQSTNREQD 416
+ G + QR+ +S++ P+ ++ + ++ E + T E+
Sbjct: 1558 HEQTTQTGSRTTGRQRTSHSESTDSEVHSGGSHRPHSREHTYGQAGSQHEEPEFTVHERH 1617
Query: 417 LLSHEQKG---RHQHGSHG 432
+H Q G H H HG
Sbjct: 1618 GTTHGQIGDTTGHSHSGHG 1636
Score = 34.7 bits (78), Expect = 0.19
Identities = 74/312 (23%), Positives = 104/312 (33%), Gaps = 48/312 (15%)
Query: 18 QAAVMGQKGGSKGRLPSEFSQFP----HGQKGQHYSGQKGKQQTESKGSFSIQYT-YHVD 72
Q+A GQ G G+ S F Q GQH SG GS S Q + +
Sbjct: 816 QSAGFGQHGSGSGQ-SSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTSGFGQH 874
Query: 73 ANDHDQSRKSQQYDLNALHKTTKSQRHLGGSQQLLHNKQEGRDHDKSKGHFHRVVIHHKG 132
+ Q Q+ + + Q G Q + E R H S G G
Sbjct: 875 RSSSGQYSGFGQHGSGSGQSSGFGQHGTGSGQYSGFGQHESRSHQSSYGQHGSGSSQSSG 934
Query: 133 GKAHRGTQNPSQDQGNSPSGKGISSQYSNTEERLWVHGLSKEQTSVSGAQKGRKQGGSQS 192
H + + G SG G SS + HG Q+ SG + G S
Sbjct: 935 YGQHGSSSGQTFGFGQHRSGSGQSSGFGQ-------HGSGSGQS--SGFGQHESGSGKSS 985
Query: 193 SYVLQTEELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCPAHQDKL------ 246
+ + + S Q+ G+ Q+ SS QT+ H+
Sbjct: 986 GFGQHESRSSQSNYGQHGSGSSQSSGYGQH-------GSSSGQTTGFGQHRSSSGQYSGF 1038
Query: 247 -QHGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHYGENGV 305
QHGS S+ QH T + G+ + Y+S S R+ YG++G
Sbjct: 1039 GQHGSGSDQSS-------GFGQHGTGS-------GQSSGFGQYESRS---RQSSYGQHG- 1080
Query: 306 QKDVSQSSIYSQ 317
SQSS Y Q
Sbjct: 1081 -SGSSQSSGYGQ 1091
Score = 31.6 bits (70), Expect = 1.6
Identities = 82/398 (20%), Positives = 130/398 (32%), Gaps = 72/398 (18%)
Query: 41 HGQKGQHYSGQKGKQQTESKGSFSIQYTYHVDANDHDQSRKSQQYDLNALHKTTKSQRHL 100
HG G S Q+G + T + S +Y+ D+ H S S + +A +
Sbjct: 2007 HGHSGHGQSTQRGSRTTGRRASGHSEYS---DSEGH--SGVSHTHSGHAHGQAGSQHGES 2061
Query: 101 GGSQQLLHNKQEGRDHDKSKGHFHRVVIHHKGGKAHRGTQNPSQDQGNSPSGKGISSQYS 160
G S H G+ D ++ H + TQ S+ G SG S+ S
Sbjct: 2062 GSSVHERHGTTHGQTGDTTR---------HAHSGHGQSTQRGSRTAGRRGSG---HSESS 2109
Query: 161 NTEERLWVHGLSKEQTSVSGAQKGRKQGGSQSSYVLQTEELVANKQQRETKNSHQNKGHY 220
++E VH S + R Q G S + + + + T+ H GH
Sbjct: 2110 DSE----VHSGVSHTHSGHTYGQARSQHGESGSAIHGRQGTIHGQTGDTTR--HGQSGHG 2163
Query: 221 QNVVEVREEHSSKVQTSLCPAHQDKLQHG-SKDIFSTQDELLVYNKNQHQTKNLNQDQQ- 278
Q+ QT + + H S D + ++ + H Q
Sbjct: 2164 QS-----------TQTGSRTTGRQRSSHSESSDSEVHSEASPTHSGHTHSQAGSRHGQSG 2212
Query: 279 ---HGRKANKISYQSSSTEERRLHYGENGVQKDVSQSSIYSQTEEKAQGKSQKQITIPSQ 335
HGR+ +T R HYG Y Q+ ++ T +
Sbjct: 2213 SSGHGRQGTTHGQTGDTT--RHAHYG-------------YGQSTQRGSR------TTGRR 2251
Query: 336 EQEHSQKANKISYQSSSTEERRLHYGENGVQKDVSQRSIYSQTEKLVAGKSQIQAPNPKQ 395
HS+ ++ + S H G Q QR Q V G+ +
Sbjct: 2252 GSGHSESSDSEVHSWGS----HTHSGHIQGQAGSQQR----QPGSTVHGRLETTHGQTGD 2303
Query: 396 EPWHGENAKGES---GQSTNREQDLLSHEQKGRHQHGS 430
HG + G+S G ++R SH + R +HGS
Sbjct: 2304 TTRHGHSGYGQSTQTGSRSSRASHFQSHSSE-RQRHGS 2340
Score = 29.3 bits (64), Expect = 7.9
Identities = 89/437 (20%), Positives = 146/437 (33%), Gaps = 64/437 (14%)
Query: 46 QHYSGQ--KGKQQTESKGSFSIQYTYHVDANDHDQSRKSQQYDLNALHKTTKSQRHLGGS 103
Q+ GQ G Q+ G + + H+ + + ++ ++ +K ++ GS
Sbjct: 364 QNCGGQWRTGSSQSSCCGQYGSGGSQSCSNGQHEYGSCGRFSNSSSSNEFSKCDQYGSGS 423
Query: 104 QQLLHNKQEGRDHDKSKGHFHRVVIHHKGGKAHRGTQNPS--QDQGNSPSGK----GISS 157
Q +Q G +S G V + H T + S DQ S SGK G
Sbjct: 424 SQSTSFEQHGTGLSQSSGFEQHVCGSGQTCGQHESTSSQSLGYDQHGSSSGKTSGFGQHG 483
Query: 158 QYSNTEERLWVHGLSKEQTS---VSGAQKGRKQGGSQSSYVLQTEELVANKQQRETKNSH 214
S G Q+S G+ G+ G Q V + R ++S+
Sbjct: 484 SGSGQSSGFGQCGSGSGQSSGFGQHGSVSGQSSGFGQHGSVSGQSSGFGQHESRSRQSSY 543
Query: 215 QNKGHYQNVVEVREEHSSKVQTSLCPAHQDKLQHGSKDIFSTQDELLVYNKNQHQTKNLN 274
G + ++ S+ + Q L G F Y Q+
Sbjct: 544 GQHGSGSSQSSGYGQYGSRETSGF---GQHGLGSGQSTGFGQ------YGSGSGQSSGFG 594
Query: 275 QDQ----------QHGRKANKISY-QSSSTEERRLHYGENGVQKDV---------SQSSI 314
Q QH ++ + SY Q SS + YG++G ++ SQS+
Sbjct: 595 QHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTG 654
Query: 315 YSQTEEKAQGKSQKQITIPSQEQ-----EHSQKANKISY-QSSSTEERRLHYGENGVQKD 368
+ Q + S + Q +H ++ SY Q + YG++G
Sbjct: 655 FGQYGSGSGQSSGFGQHVSGSGQSSGFGQHESRSGHSSYGQHGFGSSQSSGYGQHGSSS- 713
Query: 369 VSQRSIYSQTEKLVAGKSQI---QAPNPKQEPWHGENAKGE------------SGQSTNR 413
Q S + Q E L +G+S Q G++ G SGQS+
Sbjct: 714 -GQTSGFGQHE-LSSGQSSSFGQHGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYG 771
Query: 414 EQDLLSHEQKGRHQHGS 430
+ S + G QHGS
Sbjct: 772 QHSSGSSQSSGYGQHGS 788
>gi|57864582 hornerin [Homo sapiens]
Length = 2850
Score = 48.1 bits (113), Expect = 2e-05
Identities = 100/437 (22%), Positives = 147/437 (33%), Gaps = 47/437 (10%)
Query: 17 KQAAVMGQKGGSKGRLPSEFSQFPHG----QKGQHYSGQKGKQQTESKGSFSIQYTYHVD 72
+Q+ GQ G G+ PS S+ HG Q + G + S+G + + H
Sbjct: 2401 RQSLGHGQHGSGSGQSPSP-SRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYE-SGSGHSS 2458
Query: 73 ANDHDQSRKSQ-----QYDLNALHKTTKSQRHLGGSQQLLHNKQEGRDHDKSKGHFHRVV 127
H +SR Q Q+ ++ H +T Q H S Q Q G +S H
Sbjct: 2459 GLGHRESRSGQSSGYGQHGSSSGHSSTHGQ-HGSTSGQSSSCGQHGASSGQSSSHGQ--- 2514
Query: 128 IHHKGGKAHRGTQNPSQDQGNSPSGKGISSQYSNTEERLWVHGLSKEQTSVSGAQKGRKQ 187
H G G G SP G G S HG ++S SG Q G
Sbjct: 2515 -HGSGSSQSSGYGRQGSGSGQSP-GHGQRGSGSRQSPSYGRHGSGSGRSSSSG-QHGSGL 2571
Query: 188 GGSQSSYVLQTEELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCPAHQDKLQ 247
G S ++ ++ + S + G+ Q+ + + S + Q
Sbjct: 2572 GESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQ 2631
Query: 248 HGSKDIFSTQDELLVYNKNQHQTKN-----LNQDQQHGRKANKISYQSSSTEERRLHYGE 302
HGS S+ Q ++ L HG+ + S +SSS G
Sbjct: 2632 HGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSG-SGRSSSRGPYESRLGH 2690
Query: 303 NGV----QKDVSQSSIYSQTEEKAQGKSQKQITIPSQEQEHSQKANKISYQSSSTEERRL 358
+ V + SS YSQ G Q S +++ + SST +
Sbjct: 2691 SSVFGQHESGSGHSSAYSQ-----HGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSS- 2744
Query: 359 HYGENGVQKDVSQRSIYSQTEKLVAGKSQIQAPNPKQEPWHGENAKGESGQSTNREQDLL 418
YG G SQ S Y + AG Q + HG + G S+ +
Sbjct: 2745 SYGHRG--SGSSQSSGYGRHG---AGSGQSLS--------HGRHGSGSGQSSSYGQHGSG 2791
Query: 419 SHEQKGRHQHGSHGGLD 435
S + G QHGS G D
Sbjct: 2792 SGQSSGYSQHGSGSGQD 2808
Score = 44.7 bits (104), Expect = 2e-04
Identities = 90/413 (21%), Positives = 139/413 (33%), Gaps = 65/413 (15%)
Query: 19 AAVMGQKGGSKGRLPSEFSQFPHGQKGQHYSGQKGKQQTESKGSFSIQYTYHVDANDHDQ 78
++V GQ G S +SQ HG H+ Q T + S T+ + + Q
Sbjct: 2221 SSVFGQHESGSGH-SSAYSQ--HGSGSGHFCSQGQHGSTSGQSS-----TFDQEGSSTGQ 2272
Query: 79 SRKSQQYDLNALHKTTKSQRHLGGSQQLLHNKQEGRDHDKSKGHFHRVVIHHKGGKAHRG 138
S Q+ + ++ Q+ G Q + GR H GH H G
Sbjct: 2273 SSSHGQHGSGSSQSSSYGQQGSGSGQ----SPSRGR-HGSGSGHSSSYGQHGSGS----- 2322
Query: 139 TQNPSQDQGNSPSGKGISSQYSNTEERLWVHGLSKEQTSVSGAQKGRKQGGSQSSYVLQT 198
S G SG G SS + + E W + S SG +Q GS+S
Sbjct: 2323 --GWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQ---- 2376
Query: 199 EELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCPAHQDKLQHGSKDIFSTQD 258
+++ +R +S + + Q H S + SL QHGS S
Sbjct: 2377 ----SSRGERHGSSSGSSSSYGQ--------HGSGSRQSLGHG-----QHGSGSGQSPSP 2419
Query: 259 ELLVYNKNQHQTKNLN-QDQQHGRKANKISYQSSSTEERRLHYGENGVQKDVSQSSIYSQ 317
+ Q+ + + G +++ Y+S S L + E+ QSS Y Q
Sbjct: 2420 SRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRES----RSGQSSGYGQ 2475
Query: 318 TEEKAQGKSQKQITIPSQEQEHSQKANKISYQSSSTEERRLHYGENGVQKDVSQRSIYSQ 377
G S + Q S +++ +S+ + H G++G SQ S Y +
Sbjct: 2476 -----HGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSH-GQHG--SGSSQSSGYGR 2527
Query: 378 TEKLVAGKSQIQAPNPKQEPWHGENAKGESGQSTNREQDLLSHEQKGRHQHGS 430
Q Q P HG+ G + S QHGS
Sbjct: 2528 -----------QGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGS 2569
Score = 44.3 bits (103), Expect = 2e-04
Identities = 93/426 (21%), Positives = 144/426 (33%), Gaps = 55/426 (12%)
Query: 17 KQAAVMGQKGGSKGRLPSEFSQFPHG----QKGQHYSGQKGKQQTESKGSFSIQYTYHVD 72
+Q+ GQ G G+ PS S+ HG Q + G + S+G + + H
Sbjct: 1461 RQSLGHGQHGSGSGQSPSP-SRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYE-SGSSHSS 1518
Query: 73 ANDHDQSRKSQ-----QYDLNALHKTTKSQRHLGGSQQLLHNKQEGRDHDKSKGHFHRVV 127
H +SR Q Q+ ++ H +T Q H S Q Q G +S H
Sbjct: 1519 GLGHRESRSGQSSGYGQHGSSSGHSSTHGQ-HGSTSGQSSSCGQHGASSGQSSSHGQ--- 1574
Query: 128 IHHKGGKAHRGTQNPSQDQGNSPSGKGISSQYSNTEERLWVHGLSKEQTSVSGAQKGRKQ 187
H G G G SP G G S HG ++S SG Q G
Sbjct: 1575 -HGSGSSQSSGYGRQGSGSGQSP-GHGQRGSGSRQSPSYGRHGSGSGRSSSSG-QHGSGL 1631
Query: 188 GGSQSSYVLQTEELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCPAHQDKLQ 247
G S ++ ++ + S + G+ Q+ + + S + Q
Sbjct: 1632 GESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQ 1691
Query: 248 HGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHYGENGVQK 307
HGS S+ + Q Q GR + + + SS +G++G
Sbjct: 1692 HGSGSRQSSG--------HGRQGSGSGQSPSRGRHGSGLGHSSS--------HGQHGSGS 1735
Query: 308 DVSQSSIYSQTEEKAQGKSQKQITIPSQEQEHSQKANKISYQSSSTEERRLHYGENGVQK 367
S S E G S ++ Q + S ++ S S + H+ G
Sbjct: 1736 GRSSSR---GPYESRSGHS----SVFGQHESGSGHSSAYSQHGSGSG----HFCSQGQHG 1784
Query: 368 DVSQRSIYSQTEKLVAGKSQIQAPNPKQEPWHGENAKGESGQSTNREQDLLSHEQKGRHQ 427
S +S E G+S HG++ G S S+ +Q S + R +
Sbjct: 1785 STSGQSSTFDQEGSSTGQSSS----------HGQHGSGSSQSSSYGQQGSGSGQSPSRGR 1834
Query: 428 HGSHGG 433
HGS G
Sbjct: 1835 HGSGSG 1840
Score = 43.9 bits (102), Expect = 3e-04
Identities = 98/442 (22%), Positives = 150/442 (33%), Gaps = 48/442 (10%)
Query: 18 QAAVMGQKGGSKGRLPSEFSQFPHGQKGQHYSGQKGKQQTESKGSFSIQYTYHVDANDHD 77
QA+ GQ G+ S+ HG H+S Q T + S S Q+ +
Sbjct: 813 QASGFGQHESGSGQGYSQ-----HGSASGHFSSQGRHGSTSGQSSSSGQHD-----SSSG 862
Query: 78 QSRKSQQYDLNALHKTTKSQRHLGGSQQLLHNKQEGRD---------HDKSKGHFHRVVI 128
QS Q++ +A H + RH GS Q + Q G H G
Sbjct: 863 QSSSYGQHE-SASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGR 921
Query: 129 HHKG-----GKAHRGTQNPSQDQGNSPSGKGISSQYSNTEERLWVHGLSKEQTSVSGAQK 183
H G G H+ + S SG G SS Y R S++ S SG+
Sbjct: 922 HGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSS 981
Query: 184 GRKQGGSQSSYVL-QTEELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCP-- 240
Q GS S L + + Q G Q+ S +S P
Sbjct: 982 SYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYE 1041
Query: 241 ---AHQDKLQHGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGRKANKISY--QSSSTEE 295
H L H S + Y ++ + + + QHG + + S Q ++
Sbjct: 1042 SGSGHSSGLGHRE----SRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSG 1097
Query: 296 RRLHYGENGVQKDVSQSSIYS-QTEEKAQGKSQKQITIPSQEQEHSQKANKISYQSSSTE 354
+ +G++G SQSS Y Q Q Q S++ + S +SSS+
Sbjct: 1098 QSSSHGQHG--SGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSG 1155
Query: 355 ERRLHYGENG----VQKDVSQRSIYSQTEKLVAGKSQIQAPNPKQEPWHGENAKGESGQS 410
+ GE+ + Q S YSQ +G S + + G++++GE S
Sbjct: 1156 QHGSGLGESSGFGHHESSSGQSSSYSQ-HGSGSGHSSGYGQHGSRS---GQSSRGERHGS 1211
Query: 411 TNREQDLLSHEQKGRHQHGSHG 432
++ G Q HG
Sbjct: 1212 SSGSSSHYGQHGSGSRQSSGHG 1233
Score = 43.5 bits (101), Expect = 4e-04
Identities = 93/423 (21%), Positives = 143/423 (33%), Gaps = 66/423 (15%)
Query: 19 AAVMGQKGGSKGRLPSEFSQFPHGQKGQHYSGQKGKQQTESKGSFSIQYTYHVDANDHDQ 78
++V GQ G S +SQ HG H+ Q T + S T+ + + Q
Sbjct: 1751 SSVFGQHESGSGH-SSAYSQ--HGSGSGHFCSQGQHGSTSGQSS-----TFDQEGSSTGQ 1802
Query: 79 SRKSQQYDLNALHKTTKSQRHLGGSQQLLHNKQEGRDHDKSKGHFHRVVIHHKGGKAHRG 138
S Q+ + ++ Q+ G Q + GR H GH H G
Sbjct: 1803 SSSHGQHGSGSSQSSSYGQQGSGSGQ----SPSRGR-HGSGSGHSSSYGQHGSGS----- 1852
Query: 139 TQNPSQDQGNSPSGKGISSQYSNTEERLWVHGLSKEQTSVSGAQKGRKQGGSQSSYVLQT 198
S G SG G SS + + E W + S SG +Q GS+S +
Sbjct: 1853 --GWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRG 1910
Query: 199 EELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCPAHQDKLQHGSKDIFSTQD 258
E Q + S + G +H S + SL QHGS S
Sbjct: 1911 E------QHGSSSGSSSSYG----------QHGSGSRQSLGHG-----QHGSGSGQSPSP 1949
Query: 259 ELLVYNKNQHQTKNLN-QDQQHGRKANKISYQSSSTEERRLHYGENGVQKDVSQSSIYSQ 317
+ Q+ + G +++ Y+S S L + E+ QSS Y Q
Sbjct: 1950 SRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRES----RSGQSSGYGQ 2005
Query: 318 TEEKAQGKSQKQITIPSQEQEHSQKANKISYQSSSTEERRLHYGENGVQKDVSQRSIYSQ 377
G S + Q S +++ +S+ + H G++G SQ S Y +
Sbjct: 2006 -----HGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSH-GQHG--SGSSQSSGYGR 2057
Query: 378 TEKLVAGKSQIQAP-------NPKQEPWHGENAKGESGQSTNREQDLLSHEQKGRHQHGS 430
G Q+P +Q P +G + G S++ + E G H S
Sbjct: 2058 -----QGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHES 2112
Query: 431 HGG 433
G
Sbjct: 2113 SSG 2115
Score = 43.1 bits (100), Expect = 5e-04
Identities = 111/511 (21%), Positives = 173/511 (33%), Gaps = 110/511 (21%)
Query: 18 QAAVMGQKGGSKGRLPSE------------FSQFPHGQKGQHYSGQKGKQQTESKG---- 61
Q++ GQ+G G+ PS + Q G SG+ G +S G
Sbjct: 1815 QSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHH 1874
Query: 62 -SFSIQ---YTYHVDANDHD-----------QSRKSQQYDLNALHKTTKSQRHLGGSQQL 106
S S Q YT H + H QS + +Q+ ++ ++ Q G Q L
Sbjct: 1875 ESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSL 1934
Query: 107 LHNKQ---EGRDHDKSKGHFHRVVIHHKGGKAHRGTQNP-------SQDQGNSPSGKGIS 156
H + G+ S+G H G + P S +G SG G S
Sbjct: 1935 GHGQHGSGSGQSPSPSRGR-------HGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHS 1987
Query: 157 SQYSNTEER------LWVHGLSKEQTSVSG------------AQKGRKQGGSQSSYVLQT 198
S + E R HG S +S G Q G G S S +
Sbjct: 1988 SGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGS 2047
Query: 199 EELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCPAHQDKLQHG----SKDIF 254
++ R+ S Q+ GH Q R+ S S QHG F
Sbjct: 2048 GSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGF 2107
Query: 255 ----STQDELLVYNKNQHQTKNLNQDQQHGRKANKIS----YQSSSTEERRLHYGENGVQ 306
S+ + Y+++ + + + QHG ++ + S + SSS R YG++G
Sbjct: 2108 GHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSR--YGQHG-- 2163
Query: 307 KDVSQSSIYSQT-----EEKAQGKSQKQITIPSQEQEHSQKANKIS----YQSSSTEERR 357
QSS + + ++G+ S +H + + S Y+S S
Sbjct: 2164 SGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSV 2223
Query: 358 LHYGENGVQKDVSQRSIYSQ------------TEKLVAGKSQI---QAPNPKQEPWHGEN 402
E+G S YSQ +G+S + + Q HG++
Sbjct: 2224 FGQHESGS----GHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQH 2279
Query: 403 AKGESGQSTNREQDLLSHEQKGRHQHGSHGG 433
G S S+ +Q S + R +HGS G
Sbjct: 2280 GSGSSQSSSYGQQGSGSGQSPSRGRHGSGSG 2310
Score = 42.7 bits (99), Expect = 7e-04
Identities = 91/415 (21%), Positives = 137/415 (33%), Gaps = 51/415 (12%)
Query: 23 GQKGGSKGRLPSEF---SQFPHGQK-GQHYSGQKGKQQTESKGSFSIQY-TYHVDANDHD 77
GQ G GR S S+ H GQH SG GS S + + +
Sbjct: 1259 GQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSG 1318
Query: 78 QSRKSQQYDLNALHKTTKSQRHLGGSQQLLHNKQ-EGRDHDKSKGHFHRVVIHHKGGKAH 136
QS Q + ++ R G SQ + + G S+G H H
Sbjct: 1319 QSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQH 1378
Query: 137 RGTQNPSQDQGNSPSGKGISSQYSNTEERLWVHGLSKEQTSVSGAQKGRKQGGSQSSYVL 196
S G SG G SS + + E W + S SG +Q GS+S
Sbjct: 1379 GSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQ-- 1436
Query: 197 QTEELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCPAHQDKLQHGSKDIFST 256
+++ +R +S + + Q H S + SL QHGS S
Sbjct: 1437 ------SSRGERHGSSSGSSSSYGQ--------HGSGSRQSLGHG-----QHGSGSGQSP 1477
Query: 257 QDELLVYNKNQHQTKNLN-QDQQHGRKANKISYQSSSTEERRLHYGENGVQKDVSQSSIY 315
+ Q+ + + G +++ Y+S S+ L + E+ QSS Y
Sbjct: 1478 SPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRES----RSGQSSGY 1533
Query: 316 SQTEEKAQGKSQKQITIPSQEQEHSQKANKISYQSSSTEERRLHYGENGVQKDVSQRSIY 375
Q G S + Q S +++ +S+ + H G++G SQ S Y
Sbjct: 1534 GQ-----HGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSH-GQHG--SGSSQSSGY 1585
Query: 376 SQTEKLVAGKSQIQAPNPKQEPWHGENAKGESGQSTNREQDLLSHEQKGRHQHGS 430
+ Q Q P HG+ G + S QHGS
Sbjct: 1586 GR-----------QGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGS 1629
Score = 40.8 bits (94), Expect = 0.003
Identities = 100/500 (20%), Positives = 168/500 (33%), Gaps = 101/500 (20%)
Query: 18 QAAVMGQKGGSKGRLPSEFSQFPHGQKGQHYSGQKGKQQTESKGSF-------------- 63
Q++ GQ G G+ P+ +GQ G SGQ T GS
Sbjct: 188 QSSGRGQCGSGSGQSPN------YGQHGSG-SGQSSSNDTHGSGSGQSSGFSQHKSSSGQ 240
Query: 64 SIQYTYHVDANDHDQS-----RKSQQYDLNALHKTTKSQ-----RHLGGSQQLLHNKQEG 113
S Y+ H + H +S Q H+++ +H GS+Q L + ++G
Sbjct: 241 SSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQG 300
Query: 114 RDHDKSKGHFHRVVIHHKGGKAHRGTQNP-------SQDQGNSPSGKGISSQYSNTEERL 166
+S H + H G H + S +G+ SG G +S + E
Sbjct: 301 SGSRQSPSH-----VRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGS 355
Query: 167 WVHGLSKEQTSVSGAQKGRKQGGSQSSYVLQTEELVANKQQRETKNSHQNKGHYQNVVEV 226
+ S SG + Q GS S + + ++ +Q + H++ + +
Sbjct: 356 GQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSG--- 412
Query: 227 REEHSSKVQTSLCPAHQDKL----------QHGSKDIFSTQDELLV-------------- 262
R +HSS S P H + QHG+ S+ V
Sbjct: 413 RGQHSSGSGQS--PGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHES 470
Query: 263 -------YNKNQHQTKNLNQDQQHGRKANKISY--QSSSTEERRLHYGENGVQKDVS--- 310
Y ++ + + + QHG ++ + S + S+ YG++G S
Sbjct: 471 SSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGH 530
Query: 311 --QSSIYSQTEEKAQGKSQKQITIPSQEQEHSQKANKIS----YQSSSTEERRLHYGEN- 363
S Q+ ++G+ + S H + + S Y+S S L + E+
Sbjct: 531 SRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESR 590
Query: 364 -------GVQKDVSQRSIYSQTEKLVAGKSQI---QAPNPKQEPWHGENAKGESGQSTNR 413
G S S +G+S Q HG++ G S S
Sbjct: 591 SGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYG 650
Query: 414 EQDLLSHEQKGRHQHGSHGG 433
+Q S + R +HGS G
Sbjct: 651 QQGSGSGQSPSRGRHGSDFG 670
Score = 40.4 bits (93), Expect = 0.003
Identities = 102/455 (22%), Positives = 148/455 (32%), Gaps = 100/455 (21%)
Query: 38 QFPHGQKGQHYSGQK----------GKQQTESKGSFSIQYTYHVDANDHDQSRKSQ---- 83
Q P +G+H SG + G ++ S+G + + H H +SR Q
Sbjct: 539 QSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYE-SGSGHSSGLGHQESRSGQSSGY 597
Query: 84 -QYDLNALHKTTKSQRHLGGSQQLLHNKQEGRDHDKSKGHFHRVVIHHKGGKAHRGTQNP 142
Q+ ++ H +T Q H S Q Q G +S H H G
Sbjct: 598 GQHGSSSGHSSTHGQ-HGSTSGQSSSCGQHGATSGQSSSHGQ----HGSGSSQSSRYGQQ 652
Query: 143 SQDQGNSPS-GK-----GISSQYSNTEERLWVHGLSKEQTSVSGAQKG--RKQGGSQSSY 194
G SPS G+ G SS Y + SVSG G K G QSS
Sbjct: 653 GSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSS- 711
Query: 195 VLQTEELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCPAHQDKLQHGSKDIF 254
Q + +SH + R+ S Q+S QHGS
Sbjct: 712 ---------GYSQHGSGSSHSSG--------YRKHGSRSGQSSRSE------QHGSSSGL 748
Query: 255 STQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQSS-----STEERRLHYGENGVQKDV 309
S+ + QH + + +Q HGR+ + + S S+ +G++G
Sbjct: 749 SS-------SYGQHGSGS-HQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSC 800
Query: 310 SQS-SIYSQTEEKAQGKSQKQITIPSQEQEHSQKANKISYQS--SSTEERRLHYGENGVQ 366
S S Y +A G Q + +H + S Q ST + G++
Sbjct: 801 SSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQH--D 858
Query: 367 KDVSQRSIYSQTEKL---VAGKSQIQAPNPKQEPWHGENAKGE----------------- 406
Q S Y Q E +G+ + Q P HG+ G
Sbjct: 859 SSSGQSSSYGQHESASHHASGRGR-HGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSS 917
Query: 407 --------SGQSTNREQDLLSHEQKGRHQHGSHGG 433
SGQS+ S + G QHGS G
Sbjct: 918 SSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSG 952
Score = 39.7 bits (91), Expect = 0.006
Identities = 102/484 (21%), Positives = 165/484 (34%), Gaps = 95/484 (19%)
Query: 23 GQKGGSKGRLPSEFSQFPHG-------QKGQHYSGQ---KGKQQTESKGSFSIQYTYHVD 72
GQ+G G+ PS HG G + SG G ES S YT H
Sbjct: 427 GQRGSGSGQSPSSGQ---HGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGS 483
Query: 73 ANDHD-----------QSRKSQQYDLNALHKTTKSQRHLGGSQQLLHNKQ---EGRDHDK 118
+ H QS + ++ +A ++ Q G Q L H++ G+
Sbjct: 484 GSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSP 543
Query: 119 SKGHFHRVVIHHKGGKAHRGTQNP-------SQDQGNSPSGKGISSQYSNTEERLWVHGL 171
S+G H+ G + P S +G SG G SS + E R
Sbjct: 544 SRGR-------HESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSG 596
Query: 172 SKEQTSVSGAQKGRKQGGSQSSYVLQTEELVANKQQRETKNSHQNKGHYQNVVEVREEHS 231
+ S SG Q GS S + A Q + H + + ++ S
Sbjct: 597 YGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSS--RYGQQGS 654
Query: 232 SKVQTSLCPAHQDKL-------QHGSKDIFSTQD--------------------ELLVYN 264
Q+ H QHGS +S+ + + Y+
Sbjct: 655 GSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYS 714
Query: 265 KNQHQTKNLNQDQQHGRKANKISY--QSSSTEERRLHYGENGVQKDVSQSSIYSQTEEKA 322
++ + + + ++HG ++ + S Q S+ YG++G QSS + + +
Sbjct: 715 QHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHG--SGSHQSSGHGR-QGSG 771
Query: 323 QGKSQKQITIPSQE---QEHSQKANKIS-------YQSSSTEERRLHYGENGVQKDVSQR 372
G S ++ S H Q + S Y+S S + E+G + SQ
Sbjct: 772 SGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQH 831
Query: 373 SIYSQ--TEKLVAGKSQIQAPNPKQEPWHGENAKGESGQSTNREQ-DLLSHEQKGRHQHG 429
S + + G + Q+ + Q SGQS++ Q + SH GR +HG
Sbjct: 832 GSASGHFSSQGRHGSTSGQSSSSGQHD-------SSSGQSSSYGQHESASHHASGRGRHG 884
Query: 430 SHGG 433
S G
Sbjct: 885 SGSG 888
Score = 32.3 bits (72), Expect = 0.93
Identities = 37/186 (19%), Positives = 75/186 (40%), Gaps = 14/186 (7%)
Query: 250 SKDIFSTQDELLVYNKNQHQTKNLNQD--QQHGRKANKISYQSSSTEERRLHYGENGVQK 307
+K + T+ L+++ Q + K + +D Q G K ++Q E+ EN Q+
Sbjct: 66 NKKVDFTEYLLMIFKLVQARNKIIGKDYCQVSGSKLRDDTHQHQE-EQEETEKEENKRQE 124
Query: 308 DVSQSSIYSQTEEKAQGKSQKQITIPSQEQEHSQKANKISYQSSSTEERRLHYGENGVQK 367
S +S E + ++ + P E + ++S+Q + + + G++
Sbjct: 125 SSFSHSSWSAGENDSYSRNVRGSLKPGTESI----SRRLSFQRDFSGQHNSYSGQSSSYG 180
Query: 368 DVSQRSIYSQTEKLVAGKSQIQAPNPKQEPWHGENAKGESGQSTNREQDLLSHEQKGRHQ 427
+ + S + + + G Q+PN +G++ G S+N S + G Q
Sbjct: 181 EQNSDS-HQSSGRGQCGSGSGQSPN------YGQHGSGSGQSSSNDTHGSGSGQSSGFSQ 233
Query: 428 HGSHGG 433
H S G
Sbjct: 234 HKSSSG 239
Score = 30.0 bits (66), Expect = 4.6
Identities = 44/207 (21%), Positives = 81/207 (39%), Gaps = 37/207 (17%)
Query: 242 HQDKLQHGS---------KDIFSTQDELLVYNKNQHQTKNL---NQDQQHGRKANKISYQ 289
+Q QHG K++ + ++ N N T ++ + D+ H +K + Y
Sbjct: 16 YQYATQHGEYDTLNKAELKELLENEFHQILKNPNDPDTVDIILQSLDRDHNKKVDFTEYL 75
Query: 290 S---SSTEERRLHYGENGVQKDVSQSSIYSQTEEKAQGKSQKQITIPSQEQEHSQKANKI 346
+ R G++ Q VS S + T + + + + ++++E+ ++ +
Sbjct: 76 LMIFKLVQARNKIIGKDYCQ--VSGSKLRDDTHQHQEEQEE------TEKEENKRQESSF 127
Query: 347 SYQSSSTEERRLHYGENGVQKDVSQRSIYSQTEKLVAGKSQIQAPNPKQEPWHGENAKGE 406
S+ S S GEN D R++ L G I Q + G++
Sbjct: 128 SHSSWSA-------GEN----DSYSRNVRGS---LKPGTESISRRLSFQRDFSGQHNSYS 173
Query: 407 SGQSTNREQDLLSHEQKGRHQHGSHGG 433
S+ EQ+ SH+ GR Q GS G
Sbjct: 174 GQSSSYGEQNSDSHQSSGRGQCGSGSG 200
>gi|55749769 CWC22 spliceosome-associated protein homolog [Homo
sapiens]
Length = 908
Score = 45.8 bits (107), Expect = 8e-05
Identities = 52/238 (21%), Positives = 98/238 (41%), Gaps = 32/238 (13%)
Query: 139 TQNPSQDQGNSPSGKGISSQYSNTEERLWVHGLSKEQTSVSGAQKGRKQGGSQSSYVLQT 198
+ + D +S S SS S++EE S S + A RK+G ++ +
Sbjct: 675 SSSSESDSSDSDSDSSDSSSESSSEES---DSSSISSHSSASANDVRKKGHGKTRSK-EV 730
Query: 199 EELVANKQ--QRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCPAHQDKLQHGS------ 250
++L+ N+Q R+ K Q GH + E RE S K H+D+ GS
Sbjct: 731 DKLIRNQQTNDRKQKERRQEHGHQETRTE-RERRSEK--------HRDQNSSGSNWRDPI 781
Query: 251 ------KDIFSTQDELLVYNKNQHQTKNLNQDQQHG-----RKANKISYQSSSTEERRLH 299
KD+ S ++ ++ Q +++ + +HG R + S+ + R+
Sbjct: 782 TKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEKHTHRIK 841
Query: 300 YGENGVQKDVSQSSIYSQTEEKAQGKSQKQITIPSQEQEHSQKANKISYQSSSTEERR 357
EN +KD S+S ++ ++ + + E S + ++ S +S ++RR
Sbjct: 842 DSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSRESKKNQDRR 899
Score = 29.6 bits (65), Expect = 6.0
Identities = 28/153 (18%), Positives = 56/153 (36%), Gaps = 9/153 (5%)
Query: 308 DVSQSSIYSQTEEKAQGKSQKQITIPSQEQEHSQKANKISYQSSSTEERRLHYGENGVQK 367
DV Q+ + A S+ + + S + SS+ N V+K
Sbjct: 660 DVEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDSSSISSHSSASANDVRK 719
Query: 368 DVSQRSIYSQTEKLVAGKSQIQAPNPKQEPWHGENAKGESGQSTNREQDLLSHEQKGRHQ 427
++ + +KL+ + ++ HG Q T E++ S + + ++
Sbjct: 720 KGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGH-------QETRTERERRSEKHRDQNS 772
Query: 428 HGSHGGLDIVIIEQEDD--SDRHLAQHLNNDRN 458
GS+ I + D S+R+ + NDR+
Sbjct: 773 SGSNWRDPITKYTSDKDVPSERNNYSRVANDRD 805
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 45.4 bits (106), Expect = 1e-04
Identities = 49/256 (19%), Positives = 104/256 (40%), Gaps = 31/256 (12%)
Query: 170 GLSKEQTSVSGAQKGR-----KQGGSQSSYVLQTEELVANKQQRETKNSHQNKGHYQNVV 224
G +EQ G Q+G+ +Q G Q + + EE + ++++ K Q G + V
Sbjct: 185 GQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQ-MGEQEEQV 243
Query: 225 EVREEHSSKVQTSLCPAHQDKLQHGSKDIFSTQDELLVYNKNQHQTKNLN---------Q 275
+ +EE K + + Q++ ++ Q+E ++ K Q + + Q
Sbjct: 244 QKQEEQVQKQEEQM--RKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQ 301
Query: 276 DQQHGRKANKISYQSSSTEERRLHYGENGVQKDVSQSSIYSQTE-----EKAQGKSQKQI 330
++Q + ++ Q E+ G+ Q + ++ Q E E+ G+ ++Q+
Sbjct: 302 EEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQM 361
Query: 331 T-----IPSQEQEHSQKANKISYQSSSTEERRLHYGENGVQKDVSQRSIYSQTEKLVAGK 385
+ QE++ ++ ++ Q ++ GE Q + + Q E++ K
Sbjct: 362 QKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQK 421
Query: 386 SQIQAPNPKQEPWHGE 401
Q++ KQE GE
Sbjct: 422 EQMR----KQEEHMGE 433
Score = 37.4 bits (85), Expect = 0.029
Identities = 49/264 (18%), Positives = 102/264 (38%), Gaps = 20/264 (7%)
Query: 170 GLSKEQTSVSGAQKG--RKQGGSQSSYVLQTEELVANKQQRETKNSHQNKGHYQNVVEVR 227
G +EQ Q+G R+Q G Q E +++E + Q + +VR
Sbjct: 129 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 188
Query: 228 EEHSSKVQTSLCPAHQDKLQHGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGRKANKIS 287
E+ + Q++ ++ Q+E + + Q + Q++Q G + ++
Sbjct: 189 EQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMR----KQEEQMGEQEEQVQ 244
Query: 288 YQSSSTEERRLHYGENGVQKDVSQSSIYSQTEE----KAQGKSQKQITIPSQEQEHSQKA 343
Q +++ + Q + + Q E+ K Q + ++Q QE++ ++
Sbjct: 245 KQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQ--TGEQEEQMREQE 302
Query: 344 NKISYQSSSTEERRLHYGENGVQKDVSQRSIYSQTEKLVAGKSQIQAPNPKQEPWHGENA 403
++ Q E+ E Q + ++ Q E++ K Q+ KQE GE
Sbjct: 303 EQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMW----KQEEQMGE-- 356
Query: 404 KGESGQSTNREQDLLSHEQKGRHQ 427
+ Q +E+ + E++ R Q
Sbjct: 357 --QEEQMQKQEEQVRKQEEQMRKQ 378
Score = 31.2 bits (69), Expect = 2.1
Identities = 34/185 (18%), Positives = 72/185 (38%), Gaps = 10/185 (5%)
Query: 182 QKGRKQGGSQSSYVLQTEELVANKQQRETKNSHQNKGHYQN---VVEVREEHSSKVQTSL 238
QK +Q Q + + EE + ++++ K Q + Q ++RE+ +
Sbjct: 251 QKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEE 310
Query: 239 CPAHQDKLQHGSKDIFSTQDELLVYNKNQ---HQTKNLNQDQQHGRKANKISYQSSST-- 293
Q++ ++ Q+E + K Q + + Q++Q G + ++ Q
Sbjct: 311 QMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRK 370
Query: 294 EERRLHYGENGVQKDVSQSSIYSQT--EEKAQGKSQKQITIPSQEQEHSQKANKISYQSS 351
+E ++ E ++K Q + E+K Q QK+ +EQ QK +
Sbjct: 371 QEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEH 430
Query: 352 STEER 356
E++
Sbjct: 431 MGEQK 435
>gi|27734775 hypothetical protein LOC286499 [Homo sapiens]
Length = 248
Score = 44.7 bits (104), Expect = 2e-04
Identities = 46/209 (22%), Positives = 94/209 (44%), Gaps = 20/209 (9%)
Query: 225 EVREEHSSKVQTSLCPAH-QDKL-QHGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGRK 282
EV+++ +K S A ++K+ ++ K++ ++++LL + N+ +K + ++ +K
Sbjct: 43 EVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLL--SGNESSSKKRERKKKRKKK 100
Query: 283 ANKISYQSSSTEERRLHYGENGVQKDVSQSSIYSQTEEKAQGKSQKQITIPSQEQEHSQK 342
+ + S SSS+ D S SS S+ EEK QGK +K+ S + S
Sbjct: 101 SCRSSSSSSSS--------------DSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSST 146
Query: 343 ANKISYQSSSTEERRLHYGENGVQKDVSQRSIYSQTEKLVAGKSQIQAPNPKQEPWHGEN 402
S S ++++ E +KDV RS+ + +K + + + + + +
Sbjct: 147 HESESESKESVKKKKKSKDETEKEKDV--RSLSKKRKKSYPDDKPLSSESSSESDYEEDV 204
Query: 403 AKGESGQSTNREQDLLSHEQKGRHQHGSH 431
+ + REQ ++K + QH H
Sbjct: 205 QAKKKRRCEEREQAKEKVKKKKKKQHKKH 233
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 44.3 bits (103), Expect = 2e-04
Identities = 54/271 (19%), Positives = 109/271 (40%), Gaps = 31/271 (11%)
Query: 205 KQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCPAHQDKLQHGSKDIFSTQDELLVYN 264
K+Q E K Q K Q R+E + Q ++K++ + ++ ++++
Sbjct: 459 KRQEEEKIREQEKRQEQEAKMWRQEEKIREQ-------EEKIREQEEKMWRQEEKIHEQE 511
Query: 265 KNQHQTKNLNQDQQHGRKANKISYQSSSTEER-RLHYGENGVQKDVS----QSSIYSQTE 319
K + + K Q++ R+ KI Q ++ ++H E ++K Q E
Sbjct: 512 KIREEEKRQEQEEMW-RQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQE 570
Query: 320 EKAQGKSQK----QITIPSQEQEHSQKANKISYQSSSTEERRLHYGENGVQKDVSQRSIY 375
EK + + +K + I QE++ ++ KI Q T+E+ GE + + +
Sbjct: 571 EKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQ 630
Query: 376 SQTEKLVAGKSQIQAPNPK----------QEPWHGENAK---GESGQSTNREQDLLSHEQ 422
Q EK+ + +I+ K QE E + + + +E+ + E+
Sbjct: 631 EQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEE 690
Query: 423 KGRHQHGSHGGLDIVIIEQEDDSDRHLAQHL 453
K R Q ++ + +QE+ H +HL
Sbjct: 691 KMRRQEEKMWEQEVRLRQQEEKMQEH-QEHL 720
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 43.5 bits (101), Expect = 4e-04
Identities = 35/177 (19%), Positives = 78/177 (44%), Gaps = 16/177 (9%)
Query: 206 QQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCPAHQDKLQHGSKDIFSTQDELLVYNK 265
++R K + +N G + +V E S + S P ++ +L + + +
Sbjct: 1262 KKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGE------SG 1315
Query: 266 NQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHYGENGVQKDVSQSSIYSQTEEKAQGK 325
+ +TK + GR K+S + S + + E+GV ++VS+ S+ E++ + +
Sbjct: 1316 EEKKTKPKEHKEVKGRNRRKVSSEDSEDSD----FQESGVSEEVSE----SEDEQRPRTR 1367
Query: 326 SQKQITIPSQEQEHSQ--KANKISYQSSSTEERRLHYGENGVQKDVSQRSIYSQTEK 380
S K+ + ++ + Q K +I Q S+ E + + E +K+ + + E+
Sbjct: 1368 SAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEE 1424
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 43.5 bits (101), Expect = 4e-04
Identities = 35/177 (19%), Positives = 78/177 (44%), Gaps = 16/177 (9%)
Query: 206 QQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCPAHQDKLQHGSKDIFSTQDELLVYNK 265
++R K + +N G + +V E S + S P ++ +L + + +
Sbjct: 1300 KKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGE------SG 1353
Query: 266 NQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHYGENGVQKDVSQSSIYSQTEEKAQGK 325
+ +TK + GR K+S + S + + E+GV ++VS+ S+ E++ + +
Sbjct: 1354 EEKKTKPKEHKEVKGRNRRKVSSEDSEDSD----FQESGVSEEVSE----SEDEQRPRTR 1405
Query: 326 SQKQITIPSQEQEHSQ--KANKISYQSSSTEERRLHYGENGVQKDVSQRSIYSQTEK 380
S K+ + ++ + Q K +I Q S+ E + + E +K+ + + E+
Sbjct: 1406 SAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEE 1462
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 43.1 bits (100), Expect = 5e-04
Identities = 56/309 (18%), Positives = 127/309 (41%), Gaps = 31/309 (10%)
Query: 163 EERLW-----VHGLSKEQTSVSGAQKGRKQGGS--QSSYVLQTEELVANKQ---QRETKN 212
E+++W +H EQ + +K ++Q Q + + EE+ K+ ++E K
Sbjct: 450 EKKMWRQEEKIH----EQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKI 505
Query: 213 SHQNKGHYQNVVEVREEHSSKVQTSLCPAHQDKLQHGSKDIFSTQDELLVYNKNQHQTKN 272
Q + ++ ++RE+ + Q++ ++++ ++++ K + K
Sbjct: 506 RKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKR 565
Query: 273 LNQDQQHGRKANKISYQSSSTEERRLHYGENGVQKDVSQSSIYSQTEEKAQGKSQKQITI 332
Q+ + R+ KI Q + E ++ + ++ Q EEK + + +K I
Sbjct: 566 QEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQ-EEKIREQEEK---I 621
Query: 333 PSQEQEHSQKANKISYQSSSTEERRLHYG-------ENGVQKDVSQRSIYSQTEKLVAGK 385
QE++ ++ KI Q T+E+ G E + + +++ Q EK+ +
Sbjct: 622 QEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQE 681
Query: 386 SQIQAPNPK---QEPWHGENAK---GESGQSTNREQDLLSHEQKGRHQHGSHGGLDIVII 439
+I+ K QE E + + + +E+ + E+K R Q ++ +
Sbjct: 682 KKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLR 741
Query: 440 EQEDDSDRH 448
+QE+ H
Sbjct: 742 QQEEKMQEH 750
>gi|4504487 histidine rich calcium binding protein precursor [Homo
sapiens]
Length = 699
Score = 43.1 bits (100), Expect = 5e-04
Identities = 76/410 (18%), Positives = 144/410 (35%), Gaps = 72/410 (17%)
Query: 41 HGQKGQHYSGQKGKQQTESKGSFSIQYTYHVDANDHDQSRKSQQYDLNALHKTTKSQRHL 100
HG +G +G+++ E + ++ S +Y A RH
Sbjct: 180 HGHRGHDGEDDEGEEEEEE---------------EEEEEEASTEYGHQA-------HRHR 217
Query: 101 GGSQQLLHNKQEGRDHDKSKGHFHRVVIHHKGGKAHRGTQNPSQDQGNSPSGKGISSQYS 160
G H +E D D S GH H H G H + D + +S +Y
Sbjct: 218 G------HGSEE--DEDVSDGHHHHGPSHRHQG--HEEDDDDDDDDDDDDDDDDVSIEYR 267
Query: 161 NTEERLWVHGLSKEQTSVSGAQKGRKQGGSQSSYVLQTEELVANKQQRETKNSHQNKGHY 220
+ R HG+ +++ VS R S+ EE + T+ HQ H
Sbjct: 268 HQAHRHQGHGIEEDE-DVSDGHHHRDPSHRHRSH----EEDDNDDDDVSTEYGHQAHRHQ 322
Query: 221 ----QNVVEVREEHSSKVQTSLCPAHQDKLQHGSKDIFSTQDELLVYNKNQHQTKNLNQD 276
+ V V EH V H+D+ + +D+ + + + QH L +
Sbjct: 323 DHRKEEVEAVSGEHHHHVPDHRHQGHRDEEE--DEDVSTER----WHQGPQHVHHGLVDE 376
Query: 277 QQHGRKANKISYQSSSTEERRLHYGENGVQKDVSQSSIYSQTEEKAQGKSQKQITIPSQE 336
++ + ++ + R H + +D ++ + + + +++ S E
Sbjct: 377 EEEEEEITVQFGHYVASHQPRGHKSDEEDFQDEYKTEVPHHHHHRVPREEDEEV---SAE 433
Query: 337 QEHSQKANKISYQSSSTEERRLHYGENGVQKDVSQRSIYSQTEKLVAGKSQIQAPNPKQE 396
H +++ S+Q T +G+ G K++S + +V +S ++
Sbjct: 434 LGHQAPSHRQSHQDEETG-----HGQRGSIKEMSH---HPPGHTVVKDRSHLR------- 478
Query: 397 PWHGENAKGESGQSTNREQDLLSHEQKGRHQHGSHGGLDIVIIEQEDDSD 446
K +S + +E+D SHE+ G +QED+ D
Sbjct: 479 -------KDDSEEEKEKEEDPGSHEEDDESSEQGEKGTHHGSRDQEDEED 521
Score = 39.7 bits (91), Expect = 0.006
Identities = 63/335 (18%), Positives = 112/335 (33%), Gaps = 36/335 (10%)
Query: 45 GQHY---SGQKGKQQTESKGSFSIQYTYHVDANDHDQSRKSQQYDLNALHKT-TKSQRHL 100
G H+ S + + + + Y A+ H RK + ++ H RH
Sbjct: 287 GHHHRDPSHRHRSHEEDDNDDDDVSTEYGHQAHRHQDHRKEEVEAVSGEHHHHVPDHRHQ 346
Query: 101 GGSQQLLHNKQEGRDHDKSKGHFHRVVIHHKGGKAHRGTQNPS------------QDQGN 148
G ++ E D D S +H+ H G + Q +G+
Sbjct: 347 G-------HRDEEEDEDVSTERWHQGPQHVHHGLVDEEEEEEEITVQFGHYVASHQPRGH 399
Query: 149 SPSGKGISSQYSNTEERLWVHGLSKEQTSVSGAQKGRKQGGSQSSYVLQTEELVANKQQR 208
+ +Y H + +E+ A+ G + + S+ Q EE ++
Sbjct: 400 KSDEEDFQDEYKTEVPHHHHHRVPREEDEEVSAELGHQAPSHRQSH--QDEETGHGQRGS 457
Query: 209 ETKNSHQNKGHYQNVVEVREEHSSKVQTSLCPAHQDKLQHGSKDIFSTQDELLVYNKNQH 268
+ SH GH VV+ R +D H D S Q E ++ ++
Sbjct: 458 IKEMSHHPPGH--TVVKDRSHLRKDDSEEEKEKEEDPGSHEEDDESSEQGEKGTHHGSRD 515
Query: 269 QTKNLNQDQQHGRKAN--------KISYQSSSTEERRLHYGENGVQKDVSQSSIYSQTEE 320
Q ++++ HG N K + EERR E G S + EE
Sbjct: 516 QEDEEDEEEGHGLSLNQEEEEEEDKEEEEEEEDEERREERAEVGAPLSPDHSE-EEEEEE 574
Query: 321 KAQGKSQKQITIPSQEQEHSQKANKISYQSSSTEE 355
+ + + + TI + ++A S + S E+
Sbjct: 575 EGLEEDEPRFTIIPNPLDRREEAGGASSEEESGED 609
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 42.7 bits (99), Expect = 7e-04
Identities = 61/326 (18%), Positives = 127/326 (38%), Gaps = 46/326 (14%)
Query: 91 HKTTKSQRHLGGSQQLLHNKQEGRDHDKSKGHFHRVVIHHKGGKAHRGTQNPSQDQGNSP 150
H +S+ G Q+ + Q R H K K + G++H ++NPS+++ +S
Sbjct: 311 HSRARSRTRKGILSQMGRHSQS-RSHSKGKSQNQSRT--PRRGRSHNWSRNPSKERSHSH 367
Query: 151 SGKGISSQYSNTEERLWVHGLSKEQTSVSGAQKGRKQGGSQSSYVLQTEELVANKQQRET 210
S S+++ER +S + GR Q GS NKQ+ +
Sbjct: 368 S-------RSSSKER------DHRGSSSPRKESGRSQSGS------------PNKQRDHS 402
Query: 211 KNSHQNKGHYQNVVEVREEHSSKVQTSLCPAHQDKLQHGSKDIFSTQDELLVYNKNQHQT 270
++ NK R+ S+ + + + ++D ++ ++++ ++
Sbjct: 403 RSRSPNK--------ARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRS 454
Query: 271 KNLNQDQQHGRKANKISYQSSSTEERRLHYGENGVQKDVSQSSIYSQTEEKAQGKSQKQI 330
N +D R NK +S S + ++D SQ S+ + + +S +
Sbjct: 455 PNKARDHSRSRSPNKARDRSRSRSPSK--------ERDHSQLGSPSKERDHRRSRSPSKE 506
Query: 331 TIPSQEQEHSQKANKISYQSSSTEERRLHYGENGVQKDVSQRSIYSQTEKLVAGKSQIQA 390
Q + S++ + +S S E +R ++D SQ S +E+ +S+ +
Sbjct: 507 RQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSR--SPSEEREHRQSRSPS 564
Query: 391 PNPKQEPWHGENAKGESGQSTNREQD 416
+ W + + E QS + ++
Sbjct: 565 KERDRRRWRSPSKERERRQSRSSSEE 590
Score = 40.0 bits (92), Expect = 0.004
Identities = 59/304 (19%), Positives = 120/304 (39%), Gaps = 40/304 (13%)
Query: 133 GKAHRGTQNPSQDQGNSPSGKGISSQYSNTEERLWVHGLSKEQ---TSVSGAQKGRKQGG 189
G A R SQ +G+ G + LSK+ SG + +
Sbjct: 153 GMASRVRTPTSQQKGSRGKSYGRPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAV 212
Query: 190 SQSSYVLQTEELVANKQQRET---KNSHQNKGHYQNVVEVREEHSSKVQTSLCPAHQDKL 246
+ S+ QT + +K++ + +S + K + Q ++ RE+ S + S ++
Sbjct: 213 TPSTAKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQA 272
Query: 247 QHGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHYGENGVQ 306
S+ +Q +++ ++++ +Q + H R + ++ S R G
Sbjct: 273 STRSRPQSHSQ------SRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGI---- 322
Query: 307 KDVSQSSIYSQTEEKAQGKSQKQITIPSQEQEHS-----QKANKISYQSSSTEERRLHYG 361
+SQ +SQ+ ++GKSQ Q P + + H+ K S+ SS++ER H G
Sbjct: 323 --LSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERD-HRG 379
Query: 362 ENGVQKDVSQRSIYSQTEKLVAGKSQIQAPNPKQEPWHGENAKGESGQSTNREQDLLSHE 421
+ +K+ +G+SQ +PN +++ H + + +R +
Sbjct: 380 SSSPRKE--------------SGRSQSGSPNKQRD--HSRSRSPNKARDRSRSRSPYKAR 423
Query: 422 QKGR 425
+ R
Sbjct: 424 DRSR 427
Score = 40.0 bits (92), Expect = 0.004
Identities = 65/346 (18%), Positives = 139/346 (40%), Gaps = 61/346 (17%)
Query: 70 HVDANDHDQSR-KSQQYDLNALHKTTKSQRHLGG-SQQLLHNKQEGRDHD------KSKG 121
H +H ++R ++++ L+ + + ++S+ H G SQ + GR H+ K +
Sbjct: 305 HSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERS 364
Query: 122 HFHRVVIHHKGGKAHRGTQNPSQDQGNSPSG---------KGISSQYSNTEERLWVHGLS 172
H H + + HRG+ +P ++ G S SG + S + R +
Sbjct: 365 HSHSRSSSKE--RDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKA 422
Query: 173 KEQTSVSGAQKGRKQGGSQSSYVLQ--TEELVANKQQRETKNSHQNKG------------ 218
++++ K R S+S Y + + NK + +++ NK
Sbjct: 423 RDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKE 482
Query: 219 --------------HYQNVVEVREEHSSKVQTSLCPAHQDKLQHGSKDIFSTQDELLVYN 264
H ++ +E + ++S + + SK+ Q
Sbjct: 483 RDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKE 542
Query: 265 KNQHQTKNLNQDQQH------GRKANKISYQSSSTEERRLHYGENGVQKDVSQS------ 312
+++ Q+++ +++++H ++ ++ ++S S E R + ++D S+S
Sbjct: 543 RDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQ 602
Query: 313 SIYSQTEEKAQGKSQKQITIPSQEQEHSQK--ANKISYQSSSTEER 356
S YS+ ++ K+ + PS+E HSQ ++K S S ST R
Sbjct: 603 SGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPR 648
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 42.7 bits (99), Expect = 7e-04
Identities = 36/157 (22%), Positives = 68/157 (43%), Gaps = 5/157 (3%)
Query: 271 KNLNQDQQHGRKANKISYQSSSTEERRLHYGENGVQKDVSQSSIYSQTEEKAQGKSQKQI 330
KN +D + +K +K + + +R GEN V+ V + + SQ E QI
Sbjct: 174 KNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQI 233
Query: 331 TI--PSQEQEHSQKANKISYQSSSTEE--RRLHYGENGVQKDVSQRSIYSQTEKLVAGKS 386
+ P QE+E Q +++IS+ EE R ++ + +R Q +K+ ++
Sbjct: 234 SSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERA 293
Query: 387 QIQAPNPKQEPWHGENAKGESGQSTNREQDLLSHEQK 423
+I+A K E + E + E+ + E++
Sbjct: 294 RIEA-EEKAAAQERERREAEERERMREEEKRAAEERQ 329
Score = 36.6 bits (83), Expect = 0.049
Identities = 48/247 (19%), Positives = 103/247 (41%), Gaps = 36/247 (14%)
Query: 203 ANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCPAHQDKLQHGSKDIFSTQDELLV 262
A +++ K ++ G + VEV ++S + + +++ + F + +
Sbjct: 45 ARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLER----L 100
Query: 263 YNKNQHQTKNLNQDQQHGRKANK-ISYQSSSTEERRLHYGENGVQKDVSQSSIYSQTEEK 321
+ + + K L + + ++ + I+ S S RR+ Q D +++ ++ EEK
Sbjct: 101 ARREERRQKRLQEALERQKEFDPTITDASLSLPSRRM-------QNDTAENET-TEKEEK 152
Query: 322 AQGKSQKQ-------ITIPSQEQ-----EHSQKANKISYQSSSTEERRLHYGENGVQKDV 369
++ + ++ +T Q+ E ++K +K + + +R GEN V+ V
Sbjct: 153 SESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMV 212
Query: 370 SQRSIYSQTEKLVAG--KSQIQAPNPKQEP---------WHGENAKGESGQSTNREQDLL 418
+++ SQ E +V QI + PKQE H E + E + E+ L
Sbjct: 213 EEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARL 272
Query: 419 SHEQKGR 425
E++ R
Sbjct: 273 EAEERER 279
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 42.7 bits (99), Expect = 7e-04
Identities = 75/374 (20%), Positives = 145/374 (38%), Gaps = 57/374 (15%)
Query: 33 PSEFSQFPHGQKGQHYSGQKGKQQTESKGSFSIQYTYHVDANDHDQSR----KSQQY--- 85
P+E ++ K + GQKGK+Q SF + ++ D + K + Y
Sbjct: 83 PTENNEEEFTSKDKKKKGQKGKKQ-----SFDDNDSEELEDKDSKSKKTAKPKVEMYSGS 137
Query: 86 ----DLNALHKTTKSQRHLGGSQQLLHNKQEGRDHDKSKGHFHRVVIHHKGGKAHRGTQN 141
D N L K K G Q + K +G + D+ + R N
Sbjct: 138 DDDDDFNKLPKKAK------GKAQKSNKKWDGSEEDEDNSKKIK----------ERSRIN 181
Query: 142 PSQDQGNSPSGKGISSQYSNTEERLWVHGLSKEQTSVSGAQKGRKQGGSQSSYVLQT-EE 200
S + G+ S ++ + + G K Q + G +S+ ++T +
Sbjct: 182 SSGESGDE------SDEFLQSRK-----GQKKNQKNKPGPNIESGNEDDDASFKIKTVAQ 230
Query: 201 LVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCPAHQDKLQHGS-KDIFSTQDE 259
A K++RE K + K + + E E + K S Q K + + K +
Sbjct: 231 KKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTG 290
Query: 260 LLVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHYGENGVQKDVSQSSIYSQTE 319
++ ++ + +T +D G K K + +E + E +K S++++ + E
Sbjct: 291 VIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEK----EKEKKKGPSKATVKAMQE 346
Query: 320 EKAQGKSQKQITIPSQEQEHSQKANKI-SYQSSSTEERRLHY--GENGVQKDVSQRSIYS 376
A+ K +++ Q++E ++ ++ ++ EE RL E QK+ ++
Sbjct: 347 ALAKLKEEEE----RQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLK 402
Query: 377 QTEKLVAGKSQIQA 390
+ KL+ KSQ +A
Sbjct: 403 KEGKLLT-KSQREA 415
>gi|7657138 golgi integral membrane protein 4 [Homo sapiens]
Length = 696
Score = 42.0 bits (97), Expect = 0.001
Identities = 71/377 (18%), Positives = 154/377 (40%), Gaps = 56/377 (14%)
Query: 78 QSRKSQQYDLNALHKTTKSQRHLGGSQQLLHNKQEGRDHDKSKGHFHRVVIHHKGGKAHR 137
+ R+ +++ + H+ + + Q H ++E HD S R + + H
Sbjct: 326 ERREPEEHQVEEEHRKALEEEEMEQVGQAEHLEEE---HDPSPEEQDR-----EWKEQHE 377
Query: 138 GTQNPSQDQGNS-----PSGKGISSQYSNTEERLWVHGLSKEQTSVSGAQKGRKQGGSQS 192
+ + +G++ PS K + S EE+L L+ +Q V AQ+ R+ +
Sbjct: 378 QREAANLLEGHARAEVYPSAKPMIKFQSPYEEQLEQQRLAVQQ--VEEAQQLREHQEALH 435
Query: 193 SYVLQTEELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCPAHQDKLQH---- 248
LQ L +QQ++ + E R +H +++ AH D + +
Sbjct: 436 QQRLQGHLLRQQEQQQQQVAREMALQRQAELEEGRPQHQEQLRQQ---AHYDAMDNDIVQ 492
Query: 249 GSKDIFSTQDELLVYNKNQHQTK------NLNQDQQHGRK-------ANKISYQSSSTEE 295
G++D +E NQHQ + N ++ ++ G + A++ + + + +
Sbjct: 493 GAEDQGIQGEEGAYERDNQHQDEAEGDPGNRHEPREQGPREADPESEADRAAVEDINPAD 552
Query: 296 RRLHYGENGVQK--DVSQSSIYSQTEEKAQGKSQKQITIPSQEQEHSQKANKISYQSSST 353
+ GE+ ++ V + ++ + EE+ Q +++ T + +EH A Q +
Sbjct: 553 DPNNQGEDEFEEAEQVREENLPDENEEQKQSNQKQENT---EVEEHLVMAGNPDQQEDNV 609
Query: 354 EERRLHYGENGVQKDVSQRSIYSQTEKLVAGKSQIQAPNPKQEPWHGENAKGESGQSTNR 413
+E+ E VQ+D+++ K +++ E +GEN + ++ +
Sbjct: 610 DEQYQEEAEEEVQEDLTEEK-----------KRELE---HNAEETYGENDENTDDKNNDG 655
Query: 414 EQDLL--SHEQKGRHQH 428
E+ + + KGR +H
Sbjct: 656 EEQEVRDDNRPKGREEH 672
>gi|153251865 hypothetical protein LOC84226 [Homo sapiens]
Length = 1984
Score = 42.0 bits (97), Expect = 0.001
Identities = 74/378 (19%), Positives = 132/378 (34%), Gaps = 61/378 (16%)
Query: 74 NDHDQSRKSQQYDLNALHKTTKSQRHLGGSQQLLHNKQEG-------RDH----DKSKGH 122
N S +SQ+ L H + + H S++ + E R+H ++S
Sbjct: 1565 NHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSPSQRNHCSPPERSCHS 1624
Query: 123 FHRVVIHHKGGKAHRGTQ-----NPSQDQGNSPSGKGISSQYSNTEERLWVHGLSKEQTS 177
+H ++HRG +PS+ SPS + H S E+
Sbjct: 1625 LSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERS--------------HRSSSERRH 1670
Query: 178 VSGAQKGRKQGGSQSSYVLQTEELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTS 237
S +Q+ + G S+ S+ +E + QR SH+ R HS ++
Sbjct: 1671 RSPSQRSHR-GPSERSHCSPSERRHRSPSQR----SHRGPSE-------RRHHSPSKRSH 1718
Query: 238 LCPAHQDKLQHGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEERR 297
PA + + S + ++ H R S +S + R
Sbjct: 1719 RSPARRSHRSPSERSHHSPSE------RSHHSPSERRHHSPSERSHCSPSERSHCSPSER 1772
Query: 298 LHYGENGVQKDVSQSSIYSQTEEKAQGKSQKQITIPSQEQEHS----QKANKISYQSSST 353
H + S+ +S +E+ S++ PS+ + HS + + + S
Sbjct: 1773 RH-------RSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLLERSHRSP 1825
Query: 354 EERRLHYGENGVQKDVSQRSIYSQTEKLVAGKSQIQAPNPKQEPWHGENAKGESGQSTNR 413
ERR H + +S+RS +S +EK + +P + H + K + R
Sbjct: 1826 SERRSHRSFERSHRRISERS-HSPSEKSHLSPLERSRCSPSERRGHSSSGK-TCHSPSER 1883
Query: 414 EQDLLSHEQKGRHQHGSH 431
S ++GR SH
Sbjct: 1884 SHRSPSGMRQGRTSERSH 1901
Score = 37.7 bits (86), Expect = 0.022
Identities = 61/313 (19%), Positives = 126/313 (40%), Gaps = 26/313 (8%)
Query: 120 KGHFHRVVIHHKGGKAHRGTQNPSQDQGNSPSGKGISSQYSNTEERLWVHGLSKEQTSVS 179
K +HR H K H+ +PS + +P G ++++ + W + S + S
Sbjct: 1523 KRTWHR---HLKDKLTHKEHNHPSFYRERTPRGPSERTRHNPS----WRNHRSPSERSQR 1575
Query: 180 GAQKGRKQGGSQSSYVLQTEELVANKQQRETKNSHQNKGHYQ------NVVEVREEHSSK 233
+ + R SQ S+ + + ++ +R ++ Q + H + + R HS
Sbjct: 1576 SSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSPSQ-RNHCSPPERSCHSLSERGLHSPS 1634
Query: 234 VQTSLCPAHQDKLQHGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQSSST 293
++ P+ + +H S S + +++ + ++ + Q+ R ++ S+ S S
Sbjct: 1635 QRSHRGPSQR---RHHSPSERSHRSPSERSHRSSSERRHRSPSQRSHRGPSERSHCSPS- 1690
Query: 294 EERRLHYGENGVQKDVSQSSIYSQTEEKAQGKSQKQITIPSQEQEHSQKANKISYQSSST 353
ERR + S+ +S ++ + +++ PS+ HS S+ S S
Sbjct: 1691 -ERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSER--SHHSPS- 1746
Query: 354 EERRLHYGENGVQKDVSQRSIYSQTEKLVAGKSQIQAPNPKQEPWHGENAKGESGQSTNR 413
ERR H S+RS S +E+ S+ + +P ++ H + + S R
Sbjct: 1747 -ERRHHSPSERSHCSPSERSHCSPSERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERR 1805
Query: 414 EQDLLSHEQKGRH 426
L ++ RH
Sbjct: 1806 RHSPL---ERSRH 1815
Score = 32.0 bits (71), Expect = 1.2
Identities = 44/268 (16%), Positives = 95/268 (35%), Gaps = 28/268 (10%)
Query: 76 HDQSRKSQQYDLNALHKTTKSQRHLGGSQQLLHNKQEGRDHDKSKGHFHRVVIHHKGGKA 135
H S++S + H++ + H S++ H+ E R H S+ +
Sbjct: 1711 HSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPS 1770
Query: 136 HRGTQNPSQDQGNSPSGKGISSQYSNTEERLWVHGLSKEQTSVSGAQKGRKQGGSQSSYV 195
R ++PS+ + +SPS K H E++ S +++ R +S +
Sbjct: 1771 ERRHRSPSERRHHSPSEKS--------------HHSPSERSHHSPSERRRHSPLERSRHS 1816
Query: 196 LQTEELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCPAHQDKLQHGSKDIFS 255
L L + + + SH++ + R HS ++ L P + + + S
Sbjct: 1817 L----LERSHRSPSERRSHRSFERSHRRISER-SHSPSEKSHLSPLERSRCSPSERRGHS 1871
Query: 256 TQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHYGENGVQKDVSQSSIY 315
+ K H + G + + S +S + R + + ++ +
Sbjct: 1872 SS------GKTCHSPSERSHRSPSGMRQGRTSERSHRSSCERTRHSPSEMRPGRPSGRNH 1925
Query: 316 SQTEEKAQGKSQKQ---ITIPSQEQEHS 340
E+++ K+ + P + HS
Sbjct: 1926 CSPSERSRRSPLKEGLKYSFPGERPSHS 1953
Score = 30.4 bits (67), Expect = 3.5
Identities = 34/159 (21%), Positives = 62/159 (38%), Gaps = 8/159 (5%)
Query: 274 NQDQQHGRKANKISYQSSSTEERRLHYGENGVQKDVSQSSIYSQTEEKAQGKSQKQITIP 333
N ++ R ++ S +SS ERR H S+ + S +E + SQ+ P
Sbjct: 1560 NPSWRNHRSPSERSQRSSL--ERRHHSPSQRSHCSPSRKNHSSPSERSWRSPSQRNHCSP 1617
Query: 334 SQEQEHSQKANKISYQSSSTEERRLHYGENGVQK-DVSQRSIYSQTEKLVAGKSQIQAPN 392
+ HS +S + + +R H G + + S+RS S +E+ S+ + +
Sbjct: 1618 PERSCHS-----LSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSSERRHRS 1672
Query: 393 PKQEPWHGENAKGESGQSTNREQDLLSHEQKGRHQHGSH 431
P Q G + + S R + +G + H
Sbjct: 1673 PSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHH 1711
Score = 30.0 bits (66), Expect = 4.6
Identities = 25/119 (21%), Positives = 41/119 (34%), Gaps = 5/119 (4%)
Query: 33 PSEFSQFPHGQKGQHYSGQKGKQQTESKGSFSIQYTYHVDANDHDQSRKSQQYDLNALHK 92
PS+ S Q+ H ++ + + S H S++S + H
Sbjct: 1633 PSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSSERRH-----RSPSQRSHRGPSERSHC 1687
Query: 93 TTKSQRHLGGSQQLLHNKQEGRDHDKSKGHFHRVVIHHKGGKAHRGTQNPSQDQGNSPS 151
+ +RH SQ+ E R H SK + R +PS+ +SPS
Sbjct: 1688 SPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPS 1746
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 41.6 bits (96), Expect = 0.002
Identities = 57/299 (19%), Positives = 117/299 (39%), Gaps = 28/299 (9%)
Query: 163 EERLWVHGLSKEQTSVSGAQKGRKQGGSQSSYVLQTEELVANKQQRETKNSHQNKGHYQN 222
EE++W K Q Q+ ++ Q + + EE++ K++ K Q + ++
Sbjct: 287 EEKMWRQE-EKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEE---KMRRQEEMMWEK 342
Query: 223 VVEVREEHSSKVQTSLCPAHQDKLQHGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGRK 282
++RE + ++K Q K Q++ + + + K Q+++ +
Sbjct: 343 EEKIRELEEKMHEQEKIREQEEKRQEEEK--IREQEK-----RQEQEAKMWRQEEKIREQ 395
Query: 283 ANKISYQSSSTEERRLHYGENGVQKDVSQSSIYSQTEEKAQGKSQKQITIPSQEQEHSQK 342
KI Q +E+ GE +K Q + EEK + + +K I QE++ ++
Sbjct: 396 EEKIREQEEMMQEQEEKMGEQE-EKMWEQEEEMQEQEEKMRRQEEK---IREQEKKIREQ 451
Query: 343 ANKISYQSSSTEERRLHYGENGVQKDVSQRSIYSQTEKLVAGKSQIQAPNPK-------- 394
KI Q +E+ GE + + + Q EK+ + +I+ K
Sbjct: 452 EEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKI 511
Query: 395 --QEPWHGENAK---GESGQSTNREQDLLSHEQKGRHQHGSHGGLDIVIIEQEDDSDRH 448
QE E + + + +E+ + E+K R Q ++ + +QE+ H
Sbjct: 512 REQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQEH 570
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 40.8 bits (94), Expect = 0.003
Identities = 73/355 (20%), Positives = 143/355 (40%), Gaps = 22/355 (6%)
Query: 43 QKGQHYSGQKGKQQTESKGSFSIQYTYHVDANDHDQSRKSQQYDLNALHKTTKSQRHLGG 102
+K Q Y+ + K ES +IQ T H D Q + +LH+ G
Sbjct: 313 KKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQQLQSRLSASETSLHRIHVELSEKGE 372
Query: 103 SQQLLHNKQEGRDHDKSKGHF---HRVVIHHKGGKAHRGTQNPSQDQGNSPSGKGISSQY 159
+ Q L K+E + + H + + + K G Q S+ + S+
Sbjct: 373 ATQKL--KEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEI-------NQLHSKL 423
Query: 160 SNTEERLW-VHGLSKEQTSVSGAQ--KGRKQGGSQSSYVLQTEELVANKQQRETKNSHQ- 215
TE +L HG KEQ +S + +Q + + EE + K T+ HQ
Sbjct: 424 LETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQL 483
Query: 216 --NKGHYQNVVEVREEHSSKVQTSLCPAHQDKLQHGSKDIFSTQDELLVYNKNQHQTKNL 273
K +Q +++ ++K++ + Q Q G KD E L+ + + +L
Sbjct: 484 DKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALL--QKSKENISL 541
Query: 274 NQDQQHGRKANKISYQSSSTEERRLHYGENGVQKDVSQSSIYSQTEEKAQGKSQKQITIP 333
+ ++ A + + + +L + +Q+ V+Q + + + ++ ++Q+ +
Sbjct: 542 LEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQAQENLHDQ 601
Query: 334 SQEQEHSQKANKISYQSSSTEERRLHYGENGVQKDVSQRSIY--SQTEKLVAGKS 386
QEQ+ +A + S T L+ N ++ VSQ I ++TE L++ ++
Sbjct: 602 VQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQLDIQIKAKTELLLSAEA 656
Score = 37.0 bits (84), Expect = 0.038
Identities = 46/240 (19%), Positives = 93/240 (38%), Gaps = 28/240 (11%)
Query: 224 VEVREEHSSKVQTSLCPAHQDKLQHGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGRKA 283
VE + +H L ++K QHG Q E+ NQ +K L ++Q G
Sbjct: 384 VETKYQHLKAEFKQLQQQREEKEQHG----LQLQSEI-----NQLHSKLLETERQLGEAH 434
Query: 284 NKISYQSSSTEERRLHYGENGVQKDVSQSSIYSQTEEKAQGKSQKQITIPSQEQEHSQKA 343
++ Q + E+ + + + S + Q +EK ++ Q + +Q+H ++
Sbjct: 435 GRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQ 494
Query: 344 NKISYQSSSTEERRLHYGENGVQKDVSQ-----RSIYSQTEKLVAGKSQIQAPNPKQEPW 398
+ Q S+T +L +N +++ + Q + I + L K I ++E
Sbjct: 495 ---ALQQSTT--AKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKEREDL 549
Query: 399 HGENAKGESGQSTNREQDLLSH---------EQKGRHQHGSHGGLDIVIIEQEDDSDRHL 449
+ + GE + + +H +K ++Q SH + +Q + HL
Sbjct: 550 YAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQAQENLHDQVQEQKAHL 609
>gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sapiens]
Length = 1758
Score = 40.4 bits (93), Expect = 0.003
Identities = 54/280 (19%), Positives = 110/280 (39%), Gaps = 21/280 (7%)
Query: 145 DQGNSPSGKGISSQYSNTEERLWVHGLSKEQTSVSGAQKGRKQGGSQSSYVLQTEELVAN 204
++ + PS K I + + H + + S S ++KG+ + S + E N
Sbjct: 1330 EKESEPSEK-IQKFTKDVSHEIIQHEVKSSKNSAS-SEKGKTKDRDYSVLEKENPEKRKN 1387
Query: 205 KQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCPAHQDKLQHGSKDIFSTQDELLVYN 264
Q E K S+ ++ + Q + + S + +TS H +KD +D+
Sbjct: 1388 STQPE-KESNLDRLNEQGNFKSLSQSSKEARTS--DKHDSTRASSNKDFTPNRDK----- 1439
Query: 265 KNQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHYGENGVQKDVSQSSIYSQTEEKAQG 324
K + T+ + ++ K + S + + G+ ++ +K G
Sbjct: 1440 KTDYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERD------LPKKGTG 1493
Query: 325 KSQKQITIPSQEQE-HSQKANKISYQSSSTEERRLHYGENGVQKDVSQRSIYSQTEKLVA 383
S+K + PS++++ H KA +Y + E +N KD + + ++ K +
Sbjct: 1494 DSKKSNSSPSRDRKPHDHKA---TYDTKRPNEETKSVDKNPC-KDREKHVLEARNNKESS 1549
Query: 384 GKSQIQAPNPKQEPWHGENAKGESGQSTNREQDLLSHEQK 423
G + NP + E G+ +ST + + LSH +
Sbjct: 1550 GNKLLYILNPPETQVEKEQITGQIDKSTVKPKPQLSHSSR 1589
Score = 39.7 bits (91), Expect = 0.006
Identities = 59/285 (20%), Positives = 112/285 (39%), Gaps = 35/285 (12%)
Query: 132 GGKAHRGTQNPSQDQGNSPSGKGISSQYSNTEERLWVHGLSKEQTSVSGAQKGRK----- 186
GG++HR ++N + S + +Q NT+ + KE + G KG K
Sbjct: 851 GGQSHR-SRNIGSNYPEKLSARDGHNQKDNTKSK------EKESENAPGDGKGNKHKKHR 903
Query: 187 --QGGSQSSYVLQTEELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCPAHQD 244
+ G +S L E L +++ RE +NK V+ R++ ++ V+ A
Sbjct: 904 KRRKGEESEGFLNPELLETSRKSREPTGVEENKTDSLFVLPSRDD-ATPVRDEPMDAESI 962
Query: 245 KLQHGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGRKANKIS-----YQSSSTEERRLH 299
+ S+ +D+ +TK N +K N + + E R
Sbjct: 963 TFKSVSEKDKRERDKP---KAKGDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSP 1019
Query: 300 YGENGVQKDVSQSSIYSQTEEKAQGKSQKQITIPSQEQEHSQKANKISYQSSSTEERRLH 359
E ++K ++ T+ + + ++IT + + HS+ A + EE+
Sbjct: 1020 RSEPPIKKAKEETPKTDNTKSSSSSQKDEKIT-GTPRKAHSKSAKEHQETKPVKEEK--- 1075
Query: 360 YGENGVQKDVSQRSIYSQTEKLVAGKSQIQAPNPKQEPWHGENAK 404
V+KD S+ ++EKL + + + PN K +P + K
Sbjct: 1076 -----VKKDYSKDV---KSEKLTTKEEKAKKPNEKNKPLDNKGEK 1112
>gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sapiens]
Length = 1792
Score = 40.4 bits (93), Expect = 0.003
Identities = 54/280 (19%), Positives = 110/280 (39%), Gaps = 21/280 (7%)
Query: 145 DQGNSPSGKGISSQYSNTEERLWVHGLSKEQTSVSGAQKGRKQGGSQSSYVLQTEELVAN 204
++ + PS K I + + H + + S S ++KG+ + S + E N
Sbjct: 1364 EKESEPSEK-IQKFTKDVSHEIIQHEVKSSKNSAS-SEKGKTKDRDYSVLEKENPEKRKN 1421
Query: 205 KQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCPAHQDKLQHGSKDIFSTQDELLVYN 264
Q E K S+ ++ + Q + + S + +TS H +KD +D+
Sbjct: 1422 STQPE-KESNLDRLNEQGNFKSLSQSSKEARTS--DKHDSTRASSNKDFTPNRDK----- 1473
Query: 265 KNQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHYGENGVQKDVSQSSIYSQTEEKAQG 324
K + T+ + ++ K + S + + G+ ++ +K G
Sbjct: 1474 KTDYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERD------LPKKGTG 1527
Query: 325 KSQKQITIPSQEQE-HSQKANKISYQSSSTEERRLHYGENGVQKDVSQRSIYSQTEKLVA 383
S+K + PS++++ H KA +Y + E +N KD + + ++ K +
Sbjct: 1528 DSKKSNSSPSRDRKPHDHKA---TYDTKRPNEETKSVDKNPC-KDREKHVLEARNNKESS 1583
Query: 384 GKSQIQAPNPKQEPWHGENAKGESGQSTNREQDLLSHEQK 423
G + NP + E G+ +ST + + LSH +
Sbjct: 1584 GNKLLYILNPPETQVEKEQITGQIDKSTVKPKPQLSHSSR 1623
Score = 39.7 bits (91), Expect = 0.006
Identities = 59/285 (20%), Positives = 112/285 (39%), Gaps = 35/285 (12%)
Query: 132 GGKAHRGTQNPSQDQGNSPSGKGISSQYSNTEERLWVHGLSKEQTSVSGAQKGRK----- 186
GG++HR ++N + S + +Q NT+ + KE + G KG K
Sbjct: 885 GGQSHR-SRNIGSNYPEKLSARDGHNQKDNTKSK------EKESENAPGDGKGNKHKKHR 937
Query: 187 --QGGSQSSYVLQTEELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCPAHQD 244
+ G +S L E L +++ RE +NK V+ R++ ++ V+ A
Sbjct: 938 KRRKGEESEGFLNPELLETSRKSREPTGVEENKTDSLFVLPSRDD-ATPVRDEPMDAESI 996
Query: 245 KLQHGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGRKANKIS-----YQSSSTEERRLH 299
+ S+ +D+ +TK N +K N + + E R
Sbjct: 997 TFKSVSEKDKRERDKP---KAKGDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSP 1053
Query: 300 YGENGVQKDVSQSSIYSQTEEKAQGKSQKQITIPSQEQEHSQKANKISYQSSSTEERRLH 359
E ++K ++ T+ + + ++IT + + HS+ A + EE+
Sbjct: 1054 RSEPPIKKAKEETPKTDNTKSSSSSQKDEKIT-GTPRKAHSKSAKEHQETKPVKEEK--- 1109
Query: 360 YGENGVQKDVSQRSIYSQTEKLVAGKSQIQAPNPKQEPWHGENAK 404
V+KD S+ ++EKL + + + PN K +P + K
Sbjct: 1110 -----VKKDYSKDV---KSEKLTTKEEKAKKPNEKNKPLDNKGEK 1146
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 40.0 bits (92), Expect = 0.004
Identities = 50/286 (17%), Positives = 116/286 (40%), Gaps = 36/286 (12%)
Query: 79 SRKSQQYDLNALHKTTKSQRHLGGSQQLLHNKQEGRDHDKSKGHFHRVVIHHKGGKAHRG 138
SRK + + + K + H ++ H + + R+H++ K HR
Sbjct: 92 SRKEKVHHRKDEKRKEKCRHHSHSAEGGKHARVKEREHERR--------------KRHRE 137
Query: 139 TQNPSQDQGNSPSGKGISSQYSNTEERLWVHGLSKEQTSVSGAQKGRKQGGSQSSYVLQT 198
Q+ ++ + + ++ ++S ER + L +++ ++ +K+ Q +
Sbjct: 138 EQDKARREWERQKRREMAREHSR-RERDRLEQLERKRERERKMREQQKEQREQKERERRA 196
Query: 199 EELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTS-------LCPAHQDKLQHGSK 251
EE ++ R ++H +RE++S KV+ S P + +L G K
Sbjct: 197 EERRKEREARREVSAHHR--------TMREDYSDKVKASHWSRSPPRPPRERFELGDGRK 248
Query: 252 DIFSTQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHYGENGVQKDVSQ 311
+ ++E + ++++ ++ A S +S S E E +++
Sbjct: 249 PV---KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEE---EEEEEEEEEEG 302
Query: 312 SSIYSQTEEKAQGKSQKQITIPSQEQEHSQKANKISYQSSSTEERR 357
S+ EE+ + + +++ T + E+ Q A ++S + S +E R
Sbjct: 303 STSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEER 348
Score = 36.6 bits (83), Expect = 0.049
Identities = 55/323 (17%), Positives = 127/323 (39%), Gaps = 36/323 (11%)
Query: 104 QQLLHNKQEGRDHDKSKGHFHRVV---------IHHKGGKAHRGTQNPSQDQGNSPSGKG 154
++ +H++++ + +K + H H H+ K HR Q+ ++ + +
Sbjct: 94 KEKVHHRKDEKRKEKCRHHSHSAEGGKHARVKEREHERRKRHREEQDKARREWERQKRRE 153
Query: 155 ISSQYSNTEERLWVHGLSKEQTSVSGAQKGRKQGGSQSSYVLQTEELVANKQQRETKNSH 214
++ ++S ER + L +++ ++ +K+ Q + EE ++ R ++H
Sbjct: 154 MAREHSR-RERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAH 212
Query: 215 QNKGHYQNVVEVREEHSSKVQTSLCPAHQDKLQHGSKDIFSTQDELLVYNKNQHQTKNLN 274
+RE++S KV+ S + ++ F D + + + ++L
Sbjct: 213 HRT--------MREDYSDKVKASHWSRSPPR---PPRERFELGDGRKPVKEEKMEERDLL 261
Query: 275 QDQQHGRKANKISYQSSSTEERRLHYGENGVQKDVSQSSIYSQTEEKAQGKSQKQITIPS 334
D Q S ER+ E+ + S S + EE+ + + ++ T
Sbjct: 262 SD-----------LQDISDSERKTSSAESSSAESGSGSE---EEEEEEEEEEEEGSTSEE 307
Query: 335 QEQEHSQKANKISYQSSSTEERRLHYGENGVQKDVSQ-RSIYSQTEKLVAGKSQIQAPNP 393
E+E ++ + S++EE E ++++S+ ++ LV +S+ +
Sbjct: 308 SEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSG 367
Query: 394 KQEPWHGENAKGESGQSTNREQD 416
+ E E +G S E D
Sbjct: 368 ESEEAEEEVGEGTPQSSALTEGD 390
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 40.0 bits (92), Expect = 0.004
Identities = 64/379 (16%), Positives = 143/379 (37%), Gaps = 34/379 (8%)
Query: 75 DHDQSRKSQQYDLNALHKTTKSQRHLGGSQQLLHNKQEGRDHDKSKGHFHRVVIHHKGGK 134
+ +Q RK ++ +L + + Q+ +Q L KQE ++ + R + +
Sbjct: 274 EEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEER--REQQERREQQ 331
Query: 135 AHRGTQNPSQDQGNSPSGKGISSQYSNTEERLWVHGLSKEQTSVSGAQKGRKQGGSQSSY 194
R Q ++Q + Q E+ L +EQ Q+ R++ +
Sbjct: 332 EERREQQLRREQEERREQQLRREQEEERREQQ----LRREQEEERREQQLRREQQLRREQ 387
Query: 195 VLQTEELVANKQQRETKNSHQNKGHYQNVVEVREE-----------HSSKVQTSLCPAHQ 243
L+ E+ + +QQ + + + + ++R E H K +
Sbjct: 388 QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRL 447
Query: 244 DKLQHGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQSSST---------- 293
+ Q +D ++E ++ + + + L +DQ+ R+ + +
Sbjct: 448 KREQEERRDWLKREEET-ERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQ 506
Query: 294 -----EERRLHYGENGVQKDVSQSSIYSQTEEKAQGKSQKQITIPSQEQEHSQKANKISY 348
EERR + +++ Q + S+ + + + + +++ + +E++ ++ +
Sbjct: 507 LRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQR 566
Query: 349 QSSSTEERRLHYGENGVQKDVSQRSIYSQTEKLVAGKSQIQAPNPKQEPWHGENAKGESG 408
EERR + ++ QR Q E+L + + +QE + K E
Sbjct: 567 LKREQEERRDQLLKREEERR-QQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEP 625
Query: 409 QSTNREQDLLSHEQKGRHQ 427
+ R+Q L S EQ+ R Q
Sbjct: 626 EEERRQQLLKSEEQEERRQ 644
Score = 38.1 bits (87), Expect = 0.017
Identities = 39/233 (16%), Positives = 100/233 (42%), Gaps = 10/233 (4%)
Query: 196 LQTEELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCPAHQDKLQHGS----K 251
L+ EL+ +++ + Q + V + EE + + ++ ++KLQ +
Sbjct: 210 LRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQR 269
Query: 252 DIFSTQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHYGENGVQKDVSQ 311
++ +++L + + + + ++QQ R + + EERR E Q++ +
Sbjct: 270 ELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERRE 329
Query: 312 SSIYSQTEEKAQGKSQKQITIPSQEQEHSQKANKI-SYQSSSTEERRLHYGENGVQKDVS 370
+ ++ + + +++ +EQE ++ ++ Q E++L + ++
Sbjct: 330 QQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQL 389
Query: 371 QRSIYSQTEKLVAGKSQIQAPNPKQEPWHGENAKGESGQSTNREQDLLSHEQK 423
+R + E+ + + Q++ +Q+ + + E Q REQ+ HEQK
Sbjct: 390 RREQQLRREQQLRREQQLRR---EQQLRREQQLRRE--QQLRREQEEERHEQK 437
Score = 36.6 bits (83), Expect = 0.049
Identities = 71/416 (17%), Positives = 156/416 (37%), Gaps = 45/416 (10%)
Query: 16 EKQAAVMGQKGGSKGRLPSEFSQFPHGQKG--------QHYSGQKGKQQTESKGSFSIQY 67
EK+ AV K KGR +F Q Q QH G++ ++ E + Q
Sbjct: 1230 EKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQR 1289
Query: 68 TYHVDANDH----------DQSRKSQQ------YDLNALHKTTKSQRHLGGSQQLLHNKQ 111
H + + RKSQ+ + + ++ R +QLL ++
Sbjct: 1290 DRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQERE 1349
Query: 112 EG--RDHDKSKGHFHRVVIHHKGGKAHRGTQNPSQDQGNSPSGKGISSQYSNTEERLWV- 168
E R ++ + + H + G+ + + Q Q E +
Sbjct: 1350 EQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLR 1409
Query: 169 ----HGLSKEQTSVSGAQKGRK-QGGSQSSYVLQTEELVANKQQRETKNSHQNKGHYQNV 223
+E+ +S ++ RK + Q + E ++Q+ + H+ + +
Sbjct: 1410 QDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQL 1469
Query: 224 VEVREE---HSSKVQTSLCPAHQDKLQHGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHG 280
++ REE H + Q +L+ +D + EL + + K L ++QQ
Sbjct: 1470 LQEREEQQLHRQERDRKFLEEEQ-QLRRQERDRKFREQEL---RSQEPERKFLEEEQQLH 1525
Query: 281 RKANKISYQSSSTEERRLHYGENGVQKDVSQSSIYSQTEEKAQGKSQKQITIPSQEQEHS 340
R+ + + EE++L E G Q+ + + + E+ Q + ++Q++ ++++
Sbjct: 1526 RQQRQRKFLQ---EEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFR 1582
Query: 341 QKANKISYQSSSTEERRLHYGENGVQKDVSQRSIYSQTEKLVAGKSQIQAPNPKQE 396
+ K+ Q +ER+ E +++ Q+ + + ++ Q+ +Q+
Sbjct: 1583 LEEQKVRRQE---QERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQ 1635
Score = 33.1 bits (74), Expect = 0.55
Identities = 44/264 (16%), Positives = 103/264 (39%), Gaps = 30/264 (11%)
Query: 199 EELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCPAHQDKLQHGSKDIFSTQD 258
EE +Q+RE + H ++ ++ +E + +L+ +D ++
Sbjct: 1648 EEPQLRRQEREQQLRHDRDRKFREEEQLLQE-----------GEEQQLRRQERDRKFREE 1696
Query: 259 ELLVYNKNQHQTKNLNQDQQHGRKANKISYQSSS-----TEERRLHYGENGVQKDVSQSS 313
E + + + + K L ++QQ R+ + ++ TE+ +L E +K + +
Sbjct: 1697 EQQL-RRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQER-YRKILEEEQ 1754
Query: 314 IYSQTEEKAQGKSQKQITIPSQEQEHSQKANKISYQSSSTEERRLHYGENGVQKDVSQRS 373
+ + EE+ + ++ +EQ ++ + Q S E R E ++++ ++
Sbjct: 1755 LRPEREEQQLRRQERDRKFREEEQLRQEREEQ---QLRSQESDRKFREEEQLRQEREEQQ 1811
Query: 374 IYSQT---------EKLVAGKSQIQAPNPKQEPWHGENAKGESGQSTNREQDLLSHEQKG 424
+ Q E+L + + + + + E +S EQ+L E++
Sbjct: 1812 LRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQK 1871
Query: 425 RHQHGSHGGLDIVIIEQEDDSDRH 448
R Q + I Q+ + RH
Sbjct: 1872 RRQERERKLREEHIRRQQKEEQRH 1895
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 39.7 bits (91), Expect = 0.006
Identities = 49/260 (18%), Positives = 104/260 (40%), Gaps = 40/260 (15%)
Query: 197 QTEELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCPAHQDKLQHGSKDIFST 256
Q E++ ++ RE + + + ++ ++RE+ Q Q+K++ + ++
Sbjct: 442 QEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMH-EQEKIRKQEEKVWRQ 500
Query: 257 QDELLVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHYGENGVQKDVSQSSIYS 316
++++ + + K Q+++ R+ KI Q E+ +K Q +
Sbjct: 501 EEKM-----HDQEEKIREQEEKMWRQEEKIREQEEKIREQE--------EKIREQEEMMQ 547
Query: 317 QTEEKA---QGKSQKQITIPSQEQEHSQKANKISYQSSSTEERRLHYGENGVQKDVSQRS 373
+ EEK + K Q+Q + QE++ ++ KI Q E+ +
Sbjct: 548 EQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQ--------------EEK 593
Query: 374 IYSQTEKLVAGKSQIQAPNPKQEPWHGENAKGESGQSTNREQDLLSHEQKGRHQHGSHGG 433
I+ Q EK+ + +Q K W E E +E+ + E+K R Q
Sbjct: 594 IWEQEEKIREQEEMMQEQEEKM--WEQEEKMCE------QEEKMQEQEEKMRRQEEKMWE 645
Query: 434 LDIVIIEQEDDSDRHLAQHL 453
++ + +QE+ H +HL
Sbjct: 646 QEVRLRQQEEKMQEH-QEHL 664
Score = 39.3 bits (90), Expect = 0.008
Identities = 53/313 (16%), Positives = 126/313 (40%), Gaps = 39/313 (12%)
Query: 163 EERLWVHGLSKEQTSVSGAQKGRKQGGSQSSYVLQTEELVANKQQRETKNSHQNKGHYQN 222
E LW + L+++Q Q+ + Q + + + EE + ++Q E + K Q
Sbjct: 287 ENELW-NRLNQQQEEKMWRQEEKIQEWEEK--IQEQEEKI--REQEEKIREQEEKMRRQE 341
Query: 223 VVEVREEHSSKVQTSLCPAHQDKLQHGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGRK 282
+ +E + Q + ++K++ + ++ ++++ + H+ + + + ++ ++
Sbjct: 342 EMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQE 401
Query: 283 ANKISYQSSSTE--------ERRLHYGENGVQKDVS-----QSSIYSQTEEKAQGKSQKQ 329
KI Q E E ++ E +++ + I+ Q + + + K Q+Q
Sbjct: 402 EEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQ 461
Query: 330 ITIPSQEQE--------------HSQKANKISYQSSSTEERRLHYGENGVQKDVSQRSIY 375
+ QE++ H Q+ + + +E ++H E +++ + ++
Sbjct: 462 EEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIRE--QEEKMW 519
Query: 376 SQTEKLVAGKSQIQAPNPK---QEPW--HGENAKGESGQSTNREQDLLSHEQKGRHQHGS 430
Q EK+ + +I+ K QE E GE + ++ + E+K R Q
Sbjct: 520 RQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEK 579
Query: 431 HGGLDIVIIEQED 443
I EQE+
Sbjct: 580 IREQKEKIREQEE 592
>gi|87299628 biorientation of chromosomes in cell division 1-like
[Homo sapiens]
Length = 3051
Score = 39.3 bits (90), Expect = 0.008
Identities = 76/382 (19%), Positives = 134/382 (35%), Gaps = 78/382 (20%)
Query: 77 DQSRKSQQYDLNALHKTTKSQRHLGGSQQLLHNKQEGRDHDKSKGHFHRVVIHHKGGKAH 136
++ + + L+ HK H G + LH+ + KG K
Sbjct: 729 EREKTPSEDKLSVKHKYKGDCMHKTGDETELHSSE-------------------KGLKVE 769
Query: 137 RGTQNPSQDQGNSPSGKGISSQYSNTEERLWVHGLSKEQTSVSGAQKGRKQGGSQSSYVL 196
Q SQ S K E +L V G K G S Y++
Sbjct: 770 ENIQKQSQQTKLSSDDKTERKSKHRNERKLSVLG---------------KDGKPVSEYII 814
Query: 197 QTEELVA---NKQQR-----ETKNSHQNKGHYQNVVEV----REEHSSKVQTSLCPAHQD 244
+T+E V NK++R +TK H+++ + ++ ++H +Q +D
Sbjct: 815 KTDENVRKENNKKERRLSAEKTKAEHKSRRSSDSKIQKDSLGSKQHGITLQRRSESYSED 874
Query: 245 KLQHGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHYGENG 304
K S ++ S V +K + +TK+L ++ K+ +S
Sbjct: 875 KCDMDSTNMDSNLKPEEVVHKEKRRTKSLLEE--------KLVLKS-------------- 912
Query: 305 VQKDVSQSSIYSQTEEKAQGKSQKQITIPSQEQEHSQKANKISYQSSSTEERRLHYGENG 364
K +Q E + Q + KQ T P ++E + + N Q S E + + E G
Sbjct: 913 --KSKTQGKQVKVVETELQEGATKQATTPKPDKEKNTEENDSEKQRKSKVEDK-PFEETG 969
Query: 365 VQKDVSQRSIYSQTEKLVAGKSQIQAPNPKQEPWHGENAKGESGQSTNREQDLLSHEQKG 424
V+ + +T A +Q + + + P E K + ++ R + LS K
Sbjct: 970 VEPVL-------ETASSSAHSTQKDSSHRAKLPLAKEKYKSDKDSTSTRLERKLSDGHKS 1022
Query: 425 RHQHGSHGGLDIVIIEQEDDSD 446
R S + + DD D
Sbjct: 1023 RSLKHSSKDIKKKDENKSDDKD 1044
>gi|62244004 modulator of estrogen induced transcription isoform b
[Homo sapiens]
Length = 1016
Score = 39.3 bits (90), Expect = 0.008
Identities = 62/326 (19%), Positives = 117/326 (35%), Gaps = 67/326 (20%)
Query: 72 DANDHDQSRKSQQYDLNALHKTTKSQRHLGGS---QQLLHNKQEGRDHDKSKGHFHRVVI 128
DA ++S+ Y++NA HK K + + G ++ + ++ DK K +
Sbjct: 266 DAIAQSPEKESKDYEMNANHKDGKKEDCVKGDPVEKEARESSKKAESGDKEKDTLKKGPS 325
Query: 129 HH-KGGKAHRGTQNPSQDQGNSPSGKGISSQYSNTE----ERLWVHGLSKEQTSVSGAQK 183
G+A ++ + +S KG +S S + + +WV GLS +
Sbjct: 326 STGASGQAKSSSKESKDSKTSSKDDKGSTSSTSGSSGSSTKNIWVSGLSSNTKAADLKNL 385
Query: 184 GRKQGGSQSSYVLQTEELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCPAHQ 243
K G S+ V+ N+ +V + SS + S C AH
Sbjct: 386 FGKYGKVLSAKVVT--------------NARSPGAKCYGIVTM----SSSTEVSRCIAH- 426
Query: 244 DKLQHGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGR--KANKISYQSSSTEERRLHYG 301
L++ + HG+ K+ S E ++
Sbjct: 427 -----------------------------LHRTELHGQLISVEKVKGDPSKKEMKK---- 453
Query: 302 ENGVQKDVSQSSIYSQTEEKAQGKSQK-QITIPSQEQEHSQKANKISYQSSSTEERRLHY 360
+ D SS S ++ +S K Q ++ +E+ S+K+ K + + E +
Sbjct: 454 ----ENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKDTKKIEGKDEK 509
Query: 361 GENGVQKDVSQRSIYSQTEKLVAGKS 386
+NG S+ S+ +K ++ KS
Sbjct: 510 NDNGASGQTSESIKKSEEKKRISSKS 535
>gi|63176611 modulator of estrogen induced transcription isoform a
[Homo sapiens]
Length = 1034
Score = 39.3 bits (90), Expect = 0.008
Identities = 62/326 (19%), Positives = 117/326 (35%), Gaps = 67/326 (20%)
Query: 72 DANDHDQSRKSQQYDLNALHKTTKSQRHLGGS---QQLLHNKQEGRDHDKSKGHFHRVVI 128
DA ++S+ Y++NA HK K + + G ++ + ++ DK K +
Sbjct: 284 DAIAQSPEKESKDYEMNANHKDGKKEDCVKGDPVEKEARESSKKAESGDKEKDTLKKGPS 343
Query: 129 HH-KGGKAHRGTQNPSQDQGNSPSGKGISSQYSNTE----ERLWVHGLSKEQTSVSGAQK 183
G+A ++ + +S KG +S S + + +WV GLS +
Sbjct: 344 STGASGQAKSSSKESKDSKTSSKDDKGSTSSTSGSSGSSTKNIWVSGLSSNTKAADLKNL 403
Query: 184 GRKQGGSQSSYVLQTEELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCPAHQ 243
K G S+ V+ N+ +V + SS + S C AH
Sbjct: 404 FGKYGKVLSAKVVT--------------NARSPGAKCYGIVTM----SSSTEVSRCIAH- 444
Query: 244 DKLQHGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGR--KANKISYQSSSTEERRLHYG 301
L++ + HG+ K+ S E ++
Sbjct: 445 -----------------------------LHRTELHGQLISVEKVKGDPSKKEMKK---- 471
Query: 302 ENGVQKDVSQSSIYSQTEEKAQGKSQK-QITIPSQEQEHSQKANKISYQSSSTEERRLHY 360
+ D SS S ++ +S K Q ++ +E+ S+K+ K + + E +
Sbjct: 472 ----ENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKDTKKIEGKDEK 527
Query: 361 GENGVQKDVSQRSIYSQTEKLVAGKS 386
+NG S+ S+ +K ++ KS
Sbjct: 528 NDNGASGQTSESIKKSEEKKRISSKS 553
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.306 0.123 0.343
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,223,384
Number of Sequences: 37866
Number of extensions: 878262
Number of successful extensions: 3750
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 301
Number of HSP's that attempted gapping in prelim test: 3156
Number of HSP's gapped (non-prelim): 663
length of query: 462
length of database: 18,247,518
effective HSP length: 106
effective length of query: 356
effective length of database: 14,233,722
effective search space: 5067205032
effective search space used: 5067205032
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.