Guide to the Human Genome
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Name: RAF1 Sequence: fasta or formatted (648aa) NCBI GI: 4506401
Description:

v-raf-1 murine leukemia viral oncogene homolog 1

Referenced in:

BCL2 Pathways, Caspases, and Programmed Cell Death
Inositol Pathways
MAP Kinase Pathways
Myc and Related Functions
Retroviral Oncogene Homologs
Ras
Non-Receptor Tyrosine Kinase Pathways

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.2         34           2
 C cysteine            2.2         14           2
 D aspartate           4.5         29           2
 E glutamate           4.5         29           2
 F phenylalanine       4.5         29           1
 G glycine             5.4         35           1
 H histidine           3.5         23           1
 I isoleucine          4.9         32           2
 K lysine              5.9         38           2
 L leucine             8.3         54           3
 M methionine          3.1         20           1
 N asparagine          4.3         28           2
 P proline             5.6         36           1
 Q glutamine           5.1         33           2
 R arginine            6.2         40           2
 S serine             10.2         66           3
 T threonine           6.3         41           2
 V valine              6.6         43           2
 W tryptophan          1.4          9           1
 Y tyrosine            2.3         15           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   v-raf-1 murine leukemia viral oncogene homolog 1 [Hom... 
ARAF                  0.540   v-raf murine sarcoma 3611 viral oncogene homolog [Hom...
BRAF                  0.517   B-Raf 
KSR1                  0.121   kinase suppressor of ras 
KSR2                  0.119   kinase suppressor of ras 2 
FYN                   0.098   protein-tyrosine kinase fyn isoform a 
FRK                   0.097   fyn-related kinase 
SRC                   0.097   proto-oncogene tyrosine-protein kinase SRC 
SRC                   0.097   proto-oncogene tyrosine-protein kinase SRC 
YES1                  0.096   viral oncogene yes-1 homolog 1 
FYN                   0.094   protein-tyrosine kinase fyn isoform b 
EPHA3                 0.092   ephrin receptor EphA3 isoform a precursor 
LYN                   0.090   Yamaguchi sarcoma viral (v-yes-1) oncogene homolog ...
LYN                   0.090   Yamaguchi sarcoma viral (v-yes-1) oncogene homolog is...
EPHA8                 0.090   ephrin receptor EphA8 isoform 1 precursor 
FGR                   0.088   proto-oncogene tyrosine-protein kinase FGR 
FGR                   0.088   proto-oncogene tyrosine-protein kinase FGR 
FGR                   0.088   proto-oncogene tyrosine-protein kinase FGR 
LCK                   0.088   lymphocyte-specific protein tyrosine kinase precurs...
LCK                   0.088   lymphocyte-specific protein tyrosine kinase precurs...
MAP3K12               0.088   mitogen-activated protein kinase kinase kinase 12 [H...
EPHB1                 0.087   ephrin receptor EphB1 precursor 
BLK                   0.087   B lymphoid tyrosine kinase 
HCK                   0.087   hemopoietic cell kinase isoform p61HCK 
EPHA5                 0.086   ephrin receptor EphA5 isoform b precursor 
EPHA5                 0.086   ephrin receptor EphA5 isoform a precursor 
EPHB4                 0.086   EPH receptor B4 precursor 
EPHA4                 0.086   ephrin receptor EphA4 
EPHB3                 0.085   ephrin receptor EphB3 precursor 
EPHB2                 0.084   ephrin receptor EphB2 isoform 1 precursor 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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