Guide to the Human Genome
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Name: MAP3K12 Sequence: fasta or formatted (859aa) NCBI GI: 21735552
Description:

mitogen-activated protein kinase kinase kinase 12

Referenced in:

MAP Kinase Pathways

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.8         50           2
 C cysteine            2.0         17           1
 D aspartate           5.0         43           2
 E glutamate           8.4         72           4
 F phenylalanine       2.0         17           1
 G glycine             9.8         84           3
 H histidine           2.9         25           2
 I isoleucine          3.1         27           2
 K lysine              4.9         42           2
 L leucine            10.7         92           3
 M methionine          1.9         16           1
 N asparagine          2.1         18           2
 P proline             9.4         81           4
 Q glutamine           3.0         26           3
 R arginine            6.9         59           3
 S serine             10.4         89           4
 T threonine           4.5         39           1
 V valine              4.7         40           2
 W tryptophan          1.4         12           1
 Y tyrosine            1.2         10           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   mitogen-activated protein kinase kinase kinase 12 [H... 
MAP3K13               0.472   mitogen-activated protein kinase kinase kinase 13 [Ho...
MAP3K10               0.147   mitogen-activated protein kinase kinase kinase 10 [H...
MAP3K11               0.134   mitogen-activated protein kinase kinase kinase 11 [Ho...
MAP3K9                0.127   mitogen-activated protein kinase kinase kinase 9 [Ho...
KIAA1804              0.125   mixed lineage kinase 4 
ZAK                   0.108   MLK-related kinase isoform 2 
ZAK                   0.108   MLK-related kinase isoform 1 
BRAF                  0.074   B-Raf 
MAP3K7                0.073   mitogen-activated protein kinase kinase kinase 7 iso...
MAP3K7                0.073   mitogen-activated protein kinase kinase kinase 7 iso...
MAP3K7                0.073   mitogen-activated protein kinase kinase kinase 7 iso...
MAP3K7                0.073   mitogen-activated protein kinase kinase kinase 7 isof...
BMX                   0.071   BMX non-receptor tyrosine kinase 
BMX                   0.071   BMX non-receptor tyrosine kinase 
ARAF                  0.069   v-raf murine sarcoma 3611 viral oncogene homolog [Hom...
FES                   0.067   feline sarcoma oncogene isoform 4 
FES                   0.067   feline sarcoma oncogene isoform 3 
FES                   0.067   feline sarcoma oncogene isoform 2 
FES                   0.067   feline sarcoma oncogene isoform 1 
CSK                   0.067   c-src tyrosine kinase 
CSK                   0.067   c-src tyrosine kinase 
FRK                   0.067   fyn-related kinase 
FGFR4                 0.066   fibroblast growth factor receptor 4 isoform 2 precur...
FGFR4                 0.066   fibroblast growth factor receptor 4 isoform 1 precur...
FGFR4                 0.066   fibroblast growth factor receptor 4 isoform 1 precur...
MATK                  0.066   megakaryocyte-associated tyrosine kinase isoform c [...
MATK                  0.066   megakaryocyte-associated tyrosine kinase isoform b [...
MATK                  0.066   megakaryocyte-associated tyrosine kinase isoform a [...
ABL1                  0.066   c-abl oncogene 1, receptor tyrosine kinase isoform a...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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