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Search of human proteins with 4506357
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4506357 myelin protein zero-like 1 isoform a [Homo sapiens]
(269 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4506357 myelin protein zero-like 1 isoform a [Homo sapiens] 543 e-155
gi|46358426 myelin protein zero-like 1 isoform b [Homo sapiens] 409 e-114
gi|226054871 myelin protein zero-like 1 isoform c [Homo sapiens] 171 5e-43
gi|4505243 myelin protein zero [Homo sapiens] 133 1e-31
gi|21536337 myelin protein zero-like 2 precursor [Homo sapiens] 103 1e-22
gi|5032247 myelin protein zero-like 2 precursor [Homo sapiens] 103 1e-22
gi|38093645 myelin protein zero-like 3 [Homo sapiens] 90 2e-18
gi|4759066 sodium channel, voltage-gated, type II, beta [Homo sa... 69 6e-12
gi|32699028 V-set and immunoglobulin domain containing 1 [Homo s... 63 2e-10
gi|4503173 coxsackie virus and adenovirus receptor precursor [Ho... 61 9e-10
gi|148664224 adhesion molecule, interacts with CXADR antigen 1 i... 55 6e-08
gi|148664207 adhesion molecule, interacts with CXADR antigen 1 i... 55 6e-08
gi|28372555 sodium channel, voltage-gated, type IV, beta isoform... 54 1e-07
gi|62865876 immunoglobulin superfamily, member 11 isoform b [Hom... 53 2e-07
gi|62865874 immunoglobulin superfamily, member 11 isoform a [Hom... 51 1e-06
gi|4506805 sodium channel, voltage-gated, type I, beta isoform a... 47 1e-05
gi|9055238 voltage-gated sodium channel beta-3 subunit precursor... 47 2e-05
gi|93587332 voltage-gated sodium channel beta-3 subunit precurso... 47 2e-05
gi|39930610 sodium channel, voltage-gated, type I, beta isoform ... 46 4e-05
gi|5031561 transmembrane glycoprotein A33 precursor [Homo sapiens] 44 1e-04
gi|42560233 poliovirus receptor-related 1 isoform 3 [Homo sapiens] 42 6e-04
gi|42560231 poliovirus receptor-related 1 isoform 2 [Homo sapiens] 42 6e-04
gi|42560237 poliovirus receptor-related 1 isoform 1 [Homo sapiens] 42 6e-04
gi|215272334 sodium channel, voltage-gated, type IV, beta isofor... 42 7e-04
gi|21361429 V-set and immunoglobulin domain containing 2 [Homo s... 41 0.001
gi|71143132 carcinoembryonic antigen-related cell adhesion molec... 39 0.004
gi|121114300 carcinoembryonic antigen-related cell adhesion mole... 39 0.006
gi|61966777 V-set and immunoglobulin domain containing 8 [Homo s... 37 0.024
gi|21361212 cytotoxic T-lymphocyte-associated protein 4 isoform ... 35 0.053
gi|149158702 major histocompatibility complex, class I, F isofor... 35 0.069
>gi|4506357 myelin protein zero-like 1 isoform a [Homo sapiens]
Length = 269
Score = 543 bits (1398), Expect = e-155
Identities = 269/269 (100%), Positives = 269/269 (100%)
Query: 1 MAASAGAGAVIAAPDSRRWLWSVLAAALGLLTAGVSALEVYTPKEIFVANGTQGKLTCKF 60
MAASAGAGAVIAAPDSRRWLWSVLAAALGLLTAGVSALEVYTPKEIFVANGTQGKLTCKF
Sbjct: 1 MAASAGAGAVIAAPDSRRWLWSVLAAALGLLTAGVSALEVYTPKEIFVANGTQGKLTCKF 60
Query: 61 KSTSTTGGLTSVSWSFQPEGADTTVSFFHYSQGQVYLGNYPPFKDRISWAGDLDKKDASI 120
KSTSTTGGLTSVSWSFQPEGADTTVSFFHYSQGQVYLGNYPPFKDRISWAGDLDKKDASI
Sbjct: 61 KSTSTTGGLTSVSWSFQPEGADTTVSFFHYSQGQVYLGNYPPFKDRISWAGDLDKKDASI 120
Query: 121 NIENMQFIHNGTYICDVKNPPDIVVQPGHIRLYVVEKENLPVFPVWVVVGIVTAVVLGLT 180
NIENMQFIHNGTYICDVKNPPDIVVQPGHIRLYVVEKENLPVFPVWVVVGIVTAVVLGLT
Sbjct: 121 NIENMQFIHNGTYICDVKNPPDIVVQPGHIRLYVVEKENLPVFPVWVVVGIVTAVVLGLT 180
Query: 181 LLISMILAVLYRRKNSKRDYTGCSTSESLSPVKQAPRKSPSDTEGLVKSLPSGSHQGPVI 240
LLISMILAVLYRRKNSKRDYTGCSTSESLSPVKQAPRKSPSDTEGLVKSLPSGSHQGPVI
Sbjct: 181 LLISMILAVLYRRKNSKRDYTGCSTSESLSPVKQAPRKSPSDTEGLVKSLPSGSHQGPVI 240
Query: 241 YAQLDHSGGHHSDKINKSESVVYADIRKN 269
YAQLDHSGGHHSDKINKSESVVYADIRKN
Sbjct: 241 YAQLDHSGGHHSDKINKSESVVYADIRKN 269
>gi|46358426 myelin protein zero-like 1 isoform b [Homo sapiens]
Length = 209
Score = 409 bits (1051), Expect = e-114
Identities = 202/205 (98%), Positives = 203/205 (99%)
Query: 1 MAASAGAGAVIAAPDSRRWLWSVLAAALGLLTAGVSALEVYTPKEIFVANGTQGKLTCKF 60
MAASAGAGAVIAAPDSRRWLWSVLAAALGLLTAGVSALEVYTPKEIFVANGTQGKLTCKF
Sbjct: 1 MAASAGAGAVIAAPDSRRWLWSVLAAALGLLTAGVSALEVYTPKEIFVANGTQGKLTCKF 60
Query: 61 KSTSTTGGLTSVSWSFQPEGADTTVSFFHYSQGQVYLGNYPPFKDRISWAGDLDKKDASI 120
KSTSTTGGLTSVSWSFQPEGADTTVSFFHYSQGQVYLGNYPPFKDRISWAGDLDKKDASI
Sbjct: 61 KSTSTTGGLTSVSWSFQPEGADTTVSFFHYSQGQVYLGNYPPFKDRISWAGDLDKKDASI 120
Query: 121 NIENMQFIHNGTYICDVKNPPDIVVQPGHIRLYVVEKENLPVFPVWVVVGIVTAVVLGLT 180
NIENMQFIHNGTYICDVKNPPDIVVQPGHIRLYVVEKENLPVFPVWVVVGIVTAVVLGLT
Sbjct: 121 NIENMQFIHNGTYICDVKNPPDIVVQPGHIRLYVVEKENLPVFPVWVVVGIVTAVVLGLT 180
Query: 181 LLISMILAVLYRRKNSKRDYTGCST 205
LLISMILAVLYRRKNSKRDYTG +
Sbjct: 181 LLISMILAVLYRRKNSKRDYTGAQS 205
>gi|226054871 myelin protein zero-like 1 isoform c [Homo sapiens]
Length = 119
Score = 171 bits (434), Expect = 5e-43
Identities = 86/86 (100%), Positives = 86/86 (100%)
Query: 1 MAASAGAGAVIAAPDSRRWLWSVLAAALGLLTAGVSALEVYTPKEIFVANGTQGKLTCKF 60
MAASAGAGAVIAAPDSRRWLWSVLAAALGLLTAGVSALEVYTPKEIFVANGTQGKLTCKF
Sbjct: 1 MAASAGAGAVIAAPDSRRWLWSVLAAALGLLTAGVSALEVYTPKEIFVANGTQGKLTCKF 60
Query: 61 KSTSTTGGLTSVSWSFQPEGADTTVS 86
KSTSTTGGLTSVSWSFQPEGADTTVS
Sbjct: 61 KSTSTTGGLTSVSWSFQPEGADTTVS 86
Score = 73.6 bits (179), Expect = 2e-13
Identities = 41/59 (69%), Positives = 42/59 (71%), Gaps = 7/59 (11%)
Query: 218 KSPSDTEGLVKSL----PSGSH---QGPVIYAQLDHSGGHHSDKINKSESVVYADIRKN 269
KS S T GL P G+ GPVIYAQLDHSGGHHSDKINKSESVVYADIRKN
Sbjct: 61 KSTSTTGGLTSVSWSFQPEGADTTVSGPVIYAQLDHSGGHHSDKINKSESVVYADIRKN 119
>gi|4505243 myelin protein zero [Homo sapiens]
Length = 258
Score = 133 bits (335), Expect = 1e-31
Identities = 85/232 (36%), Positives = 119/232 (51%), Gaps = 25/232 (10%)
Query: 23 VLAAAL--GLLTAGVSALEVYTPKEIFVANGTQGKLTCKFKSTSTTGGLTSVSWSFQPEG 80
+LA L L+ + A+ VYT +E+ A G++ L C F S+ S +W +QPEG
Sbjct: 23 ILAVLLFSSLVLSPAQAIVVYTDREVHGAVGSRVTLHCSFWSSEWVSDDISFTWRYQPEG 82
Query: 81 ADTTVSFFHYSQGQVYLGNYPPFKDRISWAGDLDKKDASINIENMQFIHNGTYICDVKNP 140
+S FHY++GQ Y+ FK+RI W GD KD SI I N+ + NGT+ CDVKNP
Sbjct: 83 GRDAISIFHYAKGQPYIDEVGTFKERIQWVGDPRWKDGSIVIHNLDYSDNGTFTCDVKNP 142
Query: 141 PDIVVQPGHIRLYVVEKENLPVFPVWVVVGIVTAVVLGLTLLISMILAV-----LYRRKN 195
PDIV + + LYV EK +P VV+G V VLG+ LL+ ++ V L R+
Sbjct: 143 PDIVGKTSQVTLYVFEK--VPT-RYGVVLGAVIGGVLGVVLLLLLLFYVVRYCWLRRQAA 199
Query: 196 SKRDYTGCSTSESLSPVKQAPRKSPSDTEGLVKSLPSGSHQGPVIYAQLDHS 247
+R + + P K A ++ Q PV+YA LDHS
Sbjct: 200 LQRRLSAMEKGKLHKPGKDASKR---------------GRQTPVLYAMLDHS 236
>gi|21536337 myelin protein zero-like 2 precursor [Homo sapiens]
Length = 215
Score = 103 bits (258), Expect = 1e-22
Identities = 59/162 (36%), Positives = 91/162 (56%), Gaps = 6/162 (3%)
Query: 35 VSALEVYTPKEIFVANGTQGKLTCKFKSTSTTGGLTSVSWSFQP--EGADTTVSFFHYSQ 92
++A+E+YT + + NGT +L C F S + G +V+W+F+P G + V ++H
Sbjct: 24 IAAVEIYTSRVLEAVNGTDARLKCTFSSFAPVGDALTVTWNFRPLDGGPEQFVFYYHIDP 83
Query: 93 GQVYLGNYPPFKDRISWAGDLDKKDASINIENMQFIHNGTYICDVKNPPDIVVQPGHIRL 152
Q G FKDR+SW G+ ++ DASI + +QF NGTY C VKNPPD+ G IRL
Sbjct: 84 FQPMSGR---FKDRVSWDGNPERYDASILLWKLQFDDNGTYTCQVKNPPDVDGVIGEIRL 140
Query: 153 YVVEKENLPVFPVWVVVGIVTAVVLGLTLLISMILAVLYRRK 194
VV ++ + I +A L + ++I ++L YR+K
Sbjct: 141 SVVHTVRFSEIH-FLALAIGSACALMIIIVIVVVLFQHYRKK 181
>gi|5032247 myelin protein zero-like 2 precursor [Homo sapiens]
Length = 215
Score = 103 bits (258), Expect = 1e-22
Identities = 59/162 (36%), Positives = 91/162 (56%), Gaps = 6/162 (3%)
Query: 35 VSALEVYTPKEIFVANGTQGKLTCKFKSTSTTGGLTSVSWSFQP--EGADTTVSFFHYSQ 92
++A+E+YT + + NGT +L C F S + G +V+W+F+P G + V ++H
Sbjct: 24 IAAVEIYTSRVLEAVNGTDARLKCTFSSFAPVGDALTVTWNFRPLDGGPEQFVFYYHIDP 83
Query: 93 GQVYLGNYPPFKDRISWAGDLDKKDASINIENMQFIHNGTYICDVKNPPDIVVQPGHIRL 152
Q G FKDR+SW G+ ++ DASI + +QF NGTY C VKNPPD+ G IRL
Sbjct: 84 FQPMSGR---FKDRVSWDGNPERYDASILLWKLQFDDNGTYTCQVKNPPDVDGVIGEIRL 140
Query: 153 YVVEKENLPVFPVWVVVGIVTAVVLGLTLLISMILAVLYRRK 194
VV ++ + I +A L + ++I ++L YR+K
Sbjct: 141 SVVHTVRFSEIH-FLALAIGSACALMIIIVIVVVLFQHYRKK 181
>gi|38093645 myelin protein zero-like 3 [Homo sapiens]
Length = 235
Score = 89.7 bits (221), Expect = 2e-18
Identities = 63/178 (35%), Positives = 89/178 (50%), Gaps = 6/178 (3%)
Query: 35 VSALEVYTPKEIFVANGTQGKLTCKFKSTSTTGGLTSVSWSFQPEGADTTVSFFHYSQGQ 94
V +LE+ + G + KL C FKSTS ++ W+++P + TVS FHY Q
Sbjct: 29 VFSLEIRADAHVRGYVGEKIKLKCTFKSTSDVTDKLTIDWTYRPPSSSHTVSIFHYQSFQ 88
Query: 95 VYLGNYPPFKDRISWAGDLDKKDASINIENMQFIHNGTYICDVKNPPDIVVQPGHIRLYV 154
Y F+DRISW G++ K DASI+I N NGT+ C VKNPPD+ L V
Sbjct: 89 -YPTTAGTFRDRISWVGNVYKGDASISISNPTIKDNGTFSCAVKNPPDVHHNIPMTELTV 147
Query: 155 VEK----ENLPVFPVWVVVGIVTAVVLGLTLLISMILAVLYRRKNSKRDYTGCSTSES 208
E+ V + ++V + +AVV+ L LL+ M +K S+ Y S S
Sbjct: 148 TERGFGTMLSSVALLSILVFVPSAVVVAL-LLVRMGRKAAGLKKRSRSGYKKSSIEVS 204
>gi|4759066 sodium channel, voltage-gated, type II, beta [Homo
sapiens]
Length = 215
Score = 68.6 bits (166), Expect = 6e-12
Identities = 49/173 (28%), Positives = 80/173 (46%), Gaps = 3/173 (1%)
Query: 37 ALEVYTPKEIFVANGTQGKLTCKFKSTSTTGGLT-SVSWSFQPEGADTTVSFFHYSQGQV 95
++EV P + V NG+ +L C F S T S++W++Q + F + +
Sbjct: 29 SMEVTVPATLNVLNGSDARLPCTFNSCYTVNHKQFSLNWTYQECNNCSEEMFLQFRMKII 88
Query: 96 YLGNYPPFKDRISWAGDLDKKDASINIENMQFIHNGTYICDVKNPPDIVVQPGHIRLYV- 154
L F+DR+ ++G+ K D S+ + N+Q G Y C + NPPD G I L V
Sbjct: 89 NL-KLERFQDRVEFSGNPSKYDVSVMLRNVQPEDEGIYNCYIMNPPDRHRGHGKIHLQVL 147
Query: 155 VEKENLPVFPVWVVVGIVTAVVLGLTLLISMILAVLYRRKNSKRDYTGCSTSE 207
+E+ V V+VG L + +L+ M++ + R+K K T E
Sbjct: 148 MEEPPERDSTVAVIVGASVGGFLAVVILVLMVVKCVRRKKEQKLSTDDLKTEE 200
>gi|32699028 V-set and immunoglobulin domain containing 1 [Homo
sapiens]
Length = 387
Score = 63.2 bits (152), Expect = 2e-10
Identities = 51/148 (34%), Positives = 73/148 (49%), Gaps = 9/148 (6%)
Query: 21 WSVLAAALGLLTAGVSALEVYTPKE-IFVANGTQGKLTCKFKSTSTTGGLTSVSWSFQPE 79
W V L L VS ++V P + V G+ L C + +T + S+ WSF +
Sbjct: 6 WKVFLI-LSCLAGQVSVVQVTIPDGFVNVTVGSNVTLICIYTTTVASREQLSIQWSFFHK 64
Query: 80 GADTTVSFFHYSQGQ-VYLGNYPPFKDRISWAGDLDKKDASINIENMQFIHNGTYICDVK 138
+S + GQ V +G FKDRI+ G D +ASI I +MQ +G YICDV
Sbjct: 65 KEMEPISIYFSQGGQAVAIGQ---FKDRIT--GSNDPGNASITISHMQPADSGIYICDVN 119
Query: 139 NPPDIVVQ-PGHIRLYVVEKENLPVFPV 165
NPPD + Q G + + V+ K + P+ V
Sbjct: 120 NPPDFLGQNQGILNVSVLVKPSKPLCSV 147
>gi|4503173 coxsackie virus and adenovirus receptor precursor [Homo
sapiens]
Length = 365
Score = 61.2 bits (147), Expect = 9e-10
Identities = 42/136 (30%), Positives = 60/136 (44%), Gaps = 12/136 (8%)
Query: 37 ALEVYTPKEIFV-ANGTQGKLTCKFKSTSTTGGLTSVSWSFQP-EGADTTVSFFHYSQGQ 94
+L + TP+E+ A G L CKF + G + W P + YS +
Sbjct: 19 SLSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVIILYSGDK 78
Query: 95 VYLGNYPPFKDRISW-AGDLDKKDASINIENMQFIHNGTYICDVKNPPD---------IV 144
+Y YP K R+ + + DL DASIN+ N+Q GTY C VK P ++
Sbjct: 79 IYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVL 138
Query: 145 VQPGHIRLYVVEKENL 160
V+P R YV E +
Sbjct: 139 VKPSGARCYVDGSEEI 154
Score = 30.4 bits (67), Expect = 1.7
Identities = 20/92 (21%), Positives = 44/92 (47%), Gaps = 12/92 (13%)
Query: 108 SWAGDLDKKDASINIENMQFIHNGTYICDVKNPPDIVVQPGHIRLYVVEKENLPVFPVWV 167
SW ++ + I+++N ++GTY C V+N + +RL VV N
Sbjct: 187 SWLAEMTS--SVISVKNASSEYSGTYSCTVRN--RVGSDQCLLRLNVVPPSN-------- 234
Query: 168 VVGIVTAVVLGLTLLISMILAVLYRRKNSKRD 199
G++ ++G L +++I +++ + +R+
Sbjct: 235 KAGLIAGAIIGTLLALALIGLIIFCCRKKRRE 266
>gi|148664224 adhesion molecule, interacts with CXADR antigen 1
isoform 2 [Homo sapiens]
Length = 384
Score = 55.1 bits (131), Expect = 6e-08
Identities = 45/193 (23%), Positives = 84/193 (43%), Gaps = 25/193 (12%)
Query: 43 PKEIFVANGTQGKLTCKFKSTSTTGGLTSVSWSFQPEGADTTVSFFHYSQGQV---YLGN 99
PKE+ V G ++ C F+ST +T V W F A + F +Y + ++ Y +
Sbjct: 130 PKELMVHVGGLIQMGCVFQSTEVKH-VTKVEWIFSGRRAKEEIVFRYYHKLRMSVEYSQS 188
Query: 100 YPPFKDRISWAGDLDKKDASINIENMQFIHNGTYICDV----------------KNPPDI 143
+ F++R++ GD+ + D SI ++ ++ G Y C + P
Sbjct: 189 WGHFQNRVNLVGDIFRNDGSIMLQGVRESDGGNYTCSIHLGNLVFKKTIVLHVSPEEPRT 248
Query: 144 VVQPGHIRLYVVEKENLPVFPVWVVVGIVTAVVLGLTLLISMILAVLYRRKNSKRDYTGC 203
+V P +R V+ L ++VGIV A +L L +LI ++ + +
Sbjct: 249 LVTPAALRPLVLGGNQLV-----IIVGIVCATILLLPVLILIVKKTCGNKSSVNSTVLVK 303
Query: 204 STSESLSPVKQAP 216
+T ++ +K+ P
Sbjct: 304 NTKKTNPEIKEKP 316
Score = 49.7 bits (117), Expect = 3e-06
Identities = 36/131 (27%), Positives = 66/131 (50%), Gaps = 6/131 (4%)
Query: 29 GLLTAGVSALEVYTPKEIFVANGTQGKLTCKFKSTSTTGGLTSVSWSFQP-EGADTTVSF 87
G + G++ L V +P E+ V G + C F+ST + + W+ P E A
Sbjct: 4 GDYSLGLNDLNV-SPPELTVHVGDSALMGCVFQSTEDKC-IFKIDWTLSPGEHAKDEYVL 61
Query: 88 FHYSQGQVYLGNYPPFKDRISWAGDLDKKDASINIENMQFIHNGTYICDVKNPPDIVVQP 147
++YS V +G F++R+ GD+ D S+ ++++Q GTYIC+++ + V
Sbjct: 62 YYYSNLSVPIGR---FQNRVHLMGDILCNDGSLLLQDVQEADQGTYICEIRLKGESQVFK 118
Query: 148 GHIRLYVVEKE 158
+ L+V+ +E
Sbjct: 119 KAVVLHVLPEE 129
>gi|148664207 adhesion molecule, interacts with CXADR antigen 1
isoform 1 [Homo sapiens]
Length = 394
Score = 55.1 bits (131), Expect = 6e-08
Identities = 45/193 (23%), Positives = 84/193 (43%), Gaps = 25/193 (12%)
Query: 43 PKEIFVANGTQGKLTCKFKSTSTTGGLTSVSWSFQPEGADTTVSFFHYSQGQV---YLGN 99
PKE+ V G ++ C F+ST +T V W F A + F +Y + ++ Y +
Sbjct: 140 PKELMVHVGGLIQMGCVFQSTEVKH-VTKVEWIFSGRRAKEEIVFRYYHKLRMSVEYSQS 198
Query: 100 YPPFKDRISWAGDLDKKDASINIENMQFIHNGTYICDV----------------KNPPDI 143
+ F++R++ GD+ + D SI ++ ++ G Y C + P
Sbjct: 199 WGHFQNRVNLVGDIFRNDGSIMLQGVRESDGGNYTCSIHLGNLVFKKTIVLHVSPEEPRT 258
Query: 144 VVQPGHIRLYVVEKENLPVFPVWVVVGIVTAVVLGLTLLISMILAVLYRRKNSKRDYTGC 203
+V P +R V+ L ++VGIV A +L L +LI ++ + +
Sbjct: 259 LVTPAALRPLVLGGNQLV-----IIVGIVCATILLLPVLILIVKKTCGNKSSVNSTVLVK 313
Query: 204 STSESLSPVKQAP 216
+T ++ +K+ P
Sbjct: 314 NTKKTNPEIKEKP 326
Score = 49.3 bits (116), Expect = 4e-06
Identities = 35/126 (27%), Positives = 64/126 (50%), Gaps = 6/126 (4%)
Query: 34 GVSALEVYTPKEIFVANGTQGKLTCKFKSTSTTGGLTSVSWSFQP-EGADTTVSFFHYSQ 92
G++ L V +P E+ V G + C F+ST + + W+ P E A ++YS
Sbjct: 19 GLNDLNV-SPPELTVHVGDSALMGCVFQSTEDKC-IFKIDWTLSPGEHAKDEYVLYYYSN 76
Query: 93 GQVYLGNYPPFKDRISWAGDLDKKDASINIENMQFIHNGTYICDVKNPPDIVVQPGHIRL 152
V +G F++R+ GD+ D S+ ++++Q GTYIC+++ + V + L
Sbjct: 77 LSVPIGR---FQNRVHLMGDILCNDGSLLLQDVQEADQGTYICEIRLKGESQVFKKAVVL 133
Query: 153 YVVEKE 158
+V+ +E
Sbjct: 134 HVLPEE 139
>gi|28372555 sodium channel, voltage-gated, type IV, beta isoform 1
precursor [Homo sapiens]
Length = 228
Score = 54.3 bits (129), Expect = 1e-07
Identities = 68/235 (28%), Positives = 106/235 (45%), Gaps = 30/235 (12%)
Query: 6 GAGAVIAAPDSRRWLWSVLAAALGLLTAGVS-ALEVYTPK--EIFVANGTQGKLTCKFKS 62
GAG AP RWL + L LGL V+ +LEV K +I+ NGT+ L C F S
Sbjct: 3 GAGDGGKAP--ARWLGTGL---LGLFLLPVTLSLEVSVGKATDIYAVNGTEILLPCTFSS 57
Query: 63 TSTTGGLTSVSWSFQPEGADTTVSFFHYSQGQVYLGNYPPF-----KDRISWAGDLDKK- 116
L W++ A F +G V P DRI+ G +K
Sbjct: 58 CFGFEDL-HFRWTYNSSDA-----FKILIEGTVKNEKSDPKVTLKDDDRITLVGSTKEKM 111
Query: 117 -DASINIENMQFIHNGTYICDVKNPPDIVVQ-PGHIRLYVVEK----ENLPVFPVWVVVG 170
+ SI + +++F G Y C VKNP + +Q I L VV++ +N + VVG
Sbjct: 112 NNISIVLRDLEFSDTGKYTCHVKNPKENNLQHHATIFLQVVDRLEEVDNTVTLIILAVVG 171
Query: 171 IVTAVVLGLTLLISMILAVLYRRKNSKRD----YTGCSTSESLSPVKQAPRKSPS 221
V +++ + L+ +I+ +L + + K++ +G +E+ P +A K PS
Sbjct: 172 GVIGLLILILLIKKLIIFILKKTREKKKECLVSSSGNDNTENGLPGSKAEEKPPS 226
>gi|62865876 immunoglobulin superfamily, member 11 isoform b [Homo
sapiens]
Length = 431
Score = 53.1 bits (126), Expect = 2e-07
Identities = 46/125 (36%), Positives = 59/125 (47%), Gaps = 5/125 (4%)
Query: 22 SVLAAALGLLTAGVSA-LEVY-TPKEIFVANGTQGKLTCKFKSTSTTGGLTSVSWSFQP- 78
S LA L L GV+A LEV +P I VA G L C F +++ L +V W P
Sbjct: 6 SPLAPLLLLSLHGVAASLEVSESPGSIQVARGQPAVLPCTFTTSAALINL-NVIWMVTPL 64
Query: 79 EGADTTVSFFHYSQGQVYLGNYPPFKDRISWAGDLDKKDASINIENMQFIHNGTYICDVK 138
A+ Y GQ++ G P F R+ + G + + SI I N Q GTY C V
Sbjct: 65 SNANQPEQVILYQGGQMFDGA-PRFHGRVGFTGTMPATNVSIFINNTQLSDTGTYQCLVN 123
Query: 139 NPPDI 143
N PDI
Sbjct: 124 NLPDI 128
>gi|62865874 immunoglobulin superfamily, member 11 isoform a [Homo
sapiens]
Length = 430
Score = 50.8 bits (120), Expect = 1e-06
Identities = 39/114 (34%), Positives = 53/114 (46%), Gaps = 4/114 (3%)
Query: 32 TAGVSALEVY-TPKEIFVANGTQGKLTCKFKSTSTTGGLTSVSWSFQP-EGADTTVSFFH 89
T ++LEV +P I VA G L C F +++ L +V W P A+
Sbjct: 16 TGVAASLEVSESPGSIQVARGQPAVLPCTFTTSAALINL-NVIWMVTPLSNANQPEQVIL 74
Query: 90 YSQGQVYLGNYPPFKDRISWAGDLDKKDASINIENMQFIHNGTYICDVKNPPDI 143
Y GQ++ G P F R+ + G + + SI I N Q GTY C V N PDI
Sbjct: 75 YQGGQMFDGA-PRFHGRVGFTGTMPATNVSIFINNTQLSDTGTYQCLVNNLPDI 127
>gi|4506805 sodium channel, voltage-gated, type I, beta isoform a
[Homo sapiens]
Length = 218
Score = 47.4 bits (111), Expect = 1e-05
Identities = 52/180 (28%), Positives = 75/180 (41%), Gaps = 14/180 (7%)
Query: 18 RWLWSVLAAALGLLTAGVSALEVYTPKEIFVANGTQGKLTC-KFKSTSTTGGLTSVSWSF 76
R L V+ AAL G +EV + E G K+ C K S T T W+F
Sbjct: 3 RLLALVVGAALVSSACG-GCVEVDSETE--AVYGMTFKILCISCKRRSETNAETFTEWTF 59
Query: 77 QPEGADTTVSFFHYSQGQVYLGNYPPFKDRISW---AGDLDKKDASINIENMQFIHNGTY 133
+ +G + V Y + L F+ R+ W G D +D SI I N+ + H+G Y
Sbjct: 60 RQKGTEEFVKILRYENEVLQLEEDERFEGRVVWNGSRGTKDLQDLSIFITNVTYNHSGDY 119
Query: 134 ICDV------KNPPDIVVQPGHIRLYVVEKENLPVFP-VWVVVGIVTAVVLGLTLLISMI 186
C V +N I + VV+K N + V ++ V VVL + L+ MI
Sbjct: 120 ECHVYRLLFFENYEHNTSVVKKIHIEVVDKANRDMASIVSEIMMYVLIVVLTIWLVAEMI 179
>gi|9055238 voltage-gated sodium channel beta-3 subunit precursor
[Homo sapiens]
Length = 215
Score = 47.0 bits (110), Expect = 2e-05
Identities = 29/99 (29%), Positives = 42/99 (42%), Gaps = 4/99 (4%)
Query: 40 VYTPKEIFVANGTQGKLTC-KFKSTSTTGGLTSVSWSFQPEGADTTVSFFHYSQGQVYLG 98
V P E G KL C T V W ++PEG + + Y G +
Sbjct: 27 VEVPSETEAVQGNPMKLRCISCMKREEVEATTVVEWFYRPEGGKDFL-IYEYRNGHQEVE 85
Query: 99 NYPPFKDRISWAGDLDKKDASINIENMQFIHNGTYICDV 137
+ PF+ R+ W G D +D SI + N+ +G Y C+V
Sbjct: 86 S--PFQGRLQWNGSKDLQDVSITVLNVTLNDSGLYTCNV 122
>gi|93587332 voltage-gated sodium channel beta-3 subunit precursor
[Homo sapiens]
Length = 215
Score = 47.0 bits (110), Expect = 2e-05
Identities = 29/99 (29%), Positives = 42/99 (42%), Gaps = 4/99 (4%)
Query: 40 VYTPKEIFVANGTQGKLTC-KFKSTSTTGGLTSVSWSFQPEGADTTVSFFHYSQGQVYLG 98
V P E G KL C T V W ++PEG + + Y G +
Sbjct: 27 VEVPSETEAVQGNPMKLRCISCMKREEVEATTVVEWFYRPEGGKDFL-IYEYRNGHQEVE 85
Query: 99 NYPPFKDRISWAGDLDKKDASINIENMQFIHNGTYICDV 137
+ PF+ R+ W G D +D SI + N+ +G Y C+V
Sbjct: 86 S--PFQGRLQWNGSKDLQDVSITVLNVTLNDSGLYTCNV 122
>gi|39930610 sodium channel, voltage-gated, type I, beta isoform b
[Homo sapiens]
Length = 268
Score = 45.8 bits (107), Expect = 4e-05
Identities = 38/124 (30%), Positives = 53/124 (42%), Gaps = 7/124 (5%)
Query: 18 RWLWSVLAAALGLLTAGVSALEVYTPKEIFVANGTQGKLTC-KFKSTSTTGGLTSVSWSF 76
R L V+ AAL G +EV + E G K+ C K S T T W+F
Sbjct: 3 RLLALVVGAALVSSACG-GCVEVDSETE--AVYGMTFKILCISCKRRSETNAETFTEWTF 59
Query: 77 QPEGADTTVSFFHYSQGQVYLGNYPPFKDRISW---AGDLDKKDASINIENMQFIHNGTY 133
+ +G + V Y + L F+ R+ W G D +D SI I N+ + H+G Y
Sbjct: 60 RQKGTEEFVKILRYENEVLQLEEDERFEGRVVWNGSRGTKDLQDLSIFITNVTYNHSGDY 119
Query: 134 ICDV 137
C V
Sbjct: 120 ECHV 123
>gi|5031561 transmembrane glycoprotein A33 precursor [Homo sapiens]
Length = 319
Score = 44.3 bits (103), Expect = 1e-04
Identities = 39/128 (30%), Positives = 61/128 (47%), Gaps = 11/128 (8%)
Query: 20 LWSVLAAALGLLTAGVSALEVYTPKEIFVANGTQGK---LTCKFK-STSTTGGLTSVSWS 75
+W VL L + V A+ V TP+++ A+ QGK L C + STS+ GL + W
Sbjct: 5 MWPVLWT-LCAVRVTVDAISVETPQDVLRAS--QGKSVTLPCTYHTSTSSREGL--IQWD 59
Query: 76 FQPEGADTTVSFFHYSQGQVYLGNYPPFKDRISWAGDLDKKDASINIENMQFIHNGTYIC 135
V + +S G +K+R+S + + ++ DASI I+ + NGTY C
Sbjct: 60 KLLLTHTERVVIWPFSNKNYIHGEL--YKNRVSISNNAEQSDASITIDQLTMADNGTYEC 117
Query: 136 DVKNPPDI 143
V D+
Sbjct: 118 SVSLMSDL 125
>gi|42560233 poliovirus receptor-related 1 isoform 3 [Homo sapiens]
Length = 352
Score = 42.0 bits (97), Expect = 6e-04
Identities = 28/124 (22%), Positives = 50/124 (40%), Gaps = 5/124 (4%)
Query: 18 RWLWSVLAAALGLLTAGVSALEVYTPKEIFVANGTQGKLTCKFKSTSTTGGLTSVSWSFQ 77
RW W + GV + V ++ GT L C F + + +T V+W
Sbjct: 12 RW-WGLALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSVKITQVTWQKS 70
Query: 78 PEGADTTVSFFHYSQGQVYLGNYPPFKDRISWAGDLDKKDASINIENMQFIHNGTYICDV 137
G+ V+ ++ S G L P+++R+ + D +I + ++ G YIC+
Sbjct: 71 TNGSKQNVAIYNPSMGVSVLA---PYRERVEFLRP-SFTDGTIRLSRLELEDEGVYICEF 126
Query: 138 KNPP 141
P
Sbjct: 127 ATFP 130
>gi|42560231 poliovirus receptor-related 1 isoform 2 [Homo sapiens]
Length = 458
Score = 42.0 bits (97), Expect = 6e-04
Identities = 28/124 (22%), Positives = 50/124 (40%), Gaps = 5/124 (4%)
Query: 18 RWLWSVLAAALGLLTAGVSALEVYTPKEIFVANGTQGKLTCKFKSTSTTGGLTSVSWSFQ 77
RW W + GV + V ++ GT L C F + + +T V+W
Sbjct: 12 RW-WGLALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSVKITQVTWQKS 70
Query: 78 PEGADTTVSFFHYSQGQVYLGNYPPFKDRISWAGDLDKKDASINIENMQFIHNGTYICDV 137
G+ V+ ++ S G L P+++R+ + D +I + ++ G YIC+
Sbjct: 71 TNGSKQNVAIYNPSMGVSVLA---PYRERVEFLRP-SFTDGTIRLSRLELEDEGVYICEF 126
Query: 138 KNPP 141
P
Sbjct: 127 ATFP 130
Score = 35.4 bits (80), Expect = 0.053
Identities = 28/100 (28%), Positives = 46/100 (46%), Gaps = 10/100 (10%)
Query: 131 GTYICDVKNPPDIVVQPGHIRLYVVEKENLPVFPVWVVVGIVTAVVLGLTLLISMILAVL 190
GTYIC+ NP I + G + + + EK P + ++ V +L++ +L V
Sbjct: 312 GTYICEATNP--IGTRSGQVEVNITEKPR-PQRGLGSAARLLAGTVAVFLILVA-VLTVF 367
Query: 191 Y---RRKNSKRDYTGCSTSESLSPVKQAPRKSPSDTEGLV 227
+ R++ S + G T + P+ Q P SPS LV
Sbjct: 368 FLYNRQQKSPPETDGAGTDQ---PLSQKPEPSPSRQSSLV 404
>gi|42560237 poliovirus receptor-related 1 isoform 1 [Homo sapiens]
Length = 517
Score = 42.0 bits (97), Expect = 6e-04
Identities = 28/124 (22%), Positives = 50/124 (40%), Gaps = 5/124 (4%)
Query: 18 RWLWSVLAAALGLLTAGVSALEVYTPKEIFVANGTQGKLTCKFKSTSTTGGLTSVSWSFQ 77
RW W + GV + V ++ GT L C F + + +T V+W
Sbjct: 12 RW-WGLALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSVKITQVTWQKS 70
Query: 78 PEGADTTVSFFHYSQGQVYLGNYPPFKDRISWAGDLDKKDASINIENMQFIHNGTYICDV 137
G+ V+ ++ S G L P+++R+ + D +I + ++ G YIC+
Sbjct: 71 TNGSKQNVAIYNPSMGVSVLA---PYRERVEFLRP-SFTDGTIRLSRLELEDEGVYICEF 126
Query: 138 KNPP 141
P
Sbjct: 127 ATFP 130
Score = 33.9 bits (76), Expect = 0.15
Identities = 21/81 (25%), Positives = 39/81 (48%), Gaps = 12/81 (14%)
Query: 131 GTYICDVKNPPDIVVQPGHIRLYVVEKENLP----------VFPVWVVVGIVTAVVLGLT 180
GTYIC+ NP I + G + + + E P P ++ G+ +++L L
Sbjct: 312 GTYICEATNP--IGTRSGQVEVNITEFPYTPSPPEHGRRAGPVPTAIIGGVAGSILLVLI 369
Query: 181 LLISMILAVLYRRKNSKRDYT 201
++ +++A+ RR K DY+
Sbjct: 370 VVGGIVVALRRRRHTFKGDYS 390
>gi|215272334 sodium channel, voltage-gated, type IV, beta isoform 3
[Homo sapiens]
Length = 118
Score = 41.6 bits (96), Expect = 7e-04
Identities = 31/112 (27%), Positives = 57/112 (50%), Gaps = 9/112 (8%)
Query: 119 SINIENMQFIHNGTYICDVKNPPDIVVQ-PGHIRLYVVEK----ENLPVFPVWVVVGIVT 173
SI + +++F G Y C VKNP + +Q I L VV++ +N + VVG V
Sbjct: 5 SIVLRDLEFSDTGKYTCHVKNPKENNLQHHATIFLQVVDRLEEVDNTVTLIILAVVGGVI 64
Query: 174 AVVLGLTLLISMILAVLYRRKNSKRD----YTGCSTSESLSPVKQAPRKSPS 221
+++ + L+ +I+ +L + + K++ +G +E+ P +A K PS
Sbjct: 65 GLLILILLIKKLIIFILKKTREKKKECLVSSSGNDNTENGLPGSKAEEKPPS 116
>gi|21361429 V-set and immunoglobulin domain containing 2 [Homo
sapiens]
Length = 327
Score = 41.2 bits (95), Expect = 0.001
Identities = 38/145 (26%), Positives = 62/145 (42%), Gaps = 15/145 (10%)
Query: 26 AALGLLTAGVSALEVYTPKE-IFVANGTQGKLTCKFKSTSTTGGLTSVSWSFQPEGADTT 84
A LG L A+EV P E + G +LTC + +++ G ++ WSF G +
Sbjct: 12 ALLGFLCLSGLAVEVKVPTEPLSTPLGKTAELTCTY--STSVGDSFALEWSFVQPGKPIS 69
Query: 85 VS--FFHYSQGQVYLGNYPPFKDRISWAGDLDKKD----ASINIENMQFIHNGTYICDVK 138
S +++ G +Y P + L A++ + ++ GTY+C V
Sbjct: 70 ESHPILYFTNGHLY-----PTGSKSKRVSLLQNPPTVGVATLKLTDVHPSDTGTYLCQVN 124
Query: 139 NPPDIVVQP-GHIRLYVVEKENLPV 162
NPPD G I L V+ + P+
Sbjct: 125 NPPDFYTNGLGLINLTVLVPPSNPL 149
>gi|71143132 carcinoembryonic antigen-related cell adhesion molecule
4 [Homo sapiens]
Length = 244
Score = 39.3 bits (90), Expect = 0.004
Identities = 30/105 (28%), Positives = 44/105 (41%), Gaps = 19/105 (18%)
Query: 155 VEKENLPVFPVWVVVGIVTAVVLGLTLLISMILAVLYR---RKNSKRDYTGCSTSESLSP 211
V + N+P PV V GIVT V++G+ L+ +++ +L R + +RD P
Sbjct: 140 VHQNNVPGLPVGAVAGIVTGVLVGVALVAALVCFLLLSRTGRASIQRDL------REQPP 193
Query: 212 VKQAPRKSPSDTEGLVKSLPSGSHQGPV----------IYAQLDH 246
P PS LPS P+ IY Q+DH
Sbjct: 194 PASTPGHGPSHRSTFSAPLPSPRTATPIYEELLYSDANIYCQIDH 238
>gi|121114300 carcinoembryonic antigen-related cell adhesion
molecule 3 precursor [Homo sapiens]
Length = 252
Score = 38.5 bits (88), Expect = 0.006
Identities = 36/126 (28%), Positives = 60/126 (47%), Gaps = 12/126 (9%)
Query: 117 DASINIENMQFIHNGTYICDVKNPPDIVVQPGHIRLYVVEKENLPVFPVWVVVGIVTAVV 176
+AS+ I+N+ G Y V D+V + + +V + EN P PV V GIVT V+
Sbjct: 104 NASLLIQNVTQNDIGFYTLQVIKS-DLVNEEATGQFHVYQ-ENAPGLPVGAVAGIVTGVL 161
Query: 177 LGLTLLISMILAVLYR---RKNSKRDYTGCSTSESLSPVKQAPRKSPSDTEGLVKSLPSG 233
+G+ L+ +++ +L R + +RD + P AP + PS + S P
Sbjct: 162 VGVALVAALVCFLLLAKTGRTSIQRDL------KEQQPQALAPGRGPSHSSAFSMS-PLS 214
Query: 234 SHQGPV 239
+ Q P+
Sbjct: 215 TAQAPL 220
>gi|61966777 V-set and immunoglobulin domain containing 8 [Homo
sapiens]
Length = 414
Score = 36.6 bits (83), Expect = 0.024
Identities = 25/98 (25%), Positives = 42/98 (42%), Gaps = 5/98 (5%)
Query: 46 IFVANGTQGKLTCKFKSTSTTGGLTSVSWSFQPEGADTTVS----FFHYSQGQVYLGNYP 101
+++A G +L C + G + + +D F Y ++ G+ P
Sbjct: 32 LYLAEGDNVRLGCPYVLDPEDYGPNGLDIEWMQVNSDPAHHRENVFLSYQDKRINHGSLP 91
Query: 102 PFKDRISWAG-DLDKKDASINIENMQFIHNGTYICDVK 138
+ R+ +A D + DASIN+ N+Q TY C VK
Sbjct: 92 HLQQRVRFAASDPSQYDASINLMNLQVSDTATYECRVK 129
>gi|21361212 cytotoxic T-lymphocyte-associated protein 4 isoform a
precursor [Homo sapiens]
Length = 223
Score = 35.4 bits (80), Expect = 0.053
Identities = 38/185 (20%), Positives = 80/185 (43%), Gaps = 12/185 (6%)
Query: 16 SRRWLWSVLAAALGLLTAGVSALEVYTPKEIFVANGTQGKLTCKFKSTSTTGGLTSVSWS 75
+R W ++L L + A+ V P + ++ C++ S G T V +
Sbjct: 17 TRTWPCTLLFFLL-FIPVFCKAMHVAQPAVVLASSRGIASFVCEYASP---GKATEVRVT 72
Query: 76 FQPEGADTTVSFFHYSQGQVYLGNYPPFKDRISWAGDLDKKDASINIENMQFIHNGTYIC 135
+ AD+ V+ +GN F D G ++ I+ ++ + G YIC
Sbjct: 73 VLRQ-ADSQVT--EVCAATYMMGNELTFLDDSICTGTSSGNQVNLTIQGLRAMDTGLYIC 129
Query: 136 DVK--NPPDIVVQPGH-IRLYVVEKENLP--VFPVWVVVGIVTAVVLGLTLLISMILAVL 190
V+ PP + G+ ++YV++ E P F +W++ + + + LL ++ L+ +
Sbjct: 130 KVELMYPPPYYLGIGNGTQIYVIDPEPCPDSDFLLWILAAVSSGLFFYSFLLTAVSLSKM 189
Query: 191 YRRKN 195
++++
Sbjct: 190 LKKRS 194
>gi|149158702 major histocompatibility complex, class I, F isoform 1
precursor [Homo sapiens]
Length = 442
Score = 35.0 bits (79), Expect = 0.069
Identities = 35/129 (27%), Positives = 61/129 (47%), Gaps = 18/129 (13%)
Query: 97 LGNYPPFKDRISWAGDLDKKDASINIENMQFIHNGTYICDVKNPPDIVVQPGHIRLYV-- 154
LG YP + ++W D +++ + + +GT+ + +VV PG + Y
Sbjct: 227 LGFYPA-EITLTWQRDGEEQTQDTELVETRPAGDGTF----QKWAAVVVPPGEEQRYTCH 281
Query: 155 VEKENLPV----------FPVWVVVGIVTA-VVLGLTLLISMILAVLYRRKNSKRDYTGC 203
V+ E LP P +VGIV VVLG + +++ AV++R+K+S R+
Sbjct: 282 VQHEGLPQPLILRWEQSPQPTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSY 341
Query: 204 STSESLSPV 212
S + + S V
Sbjct: 342 SQAAAYSVV 350
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.133 0.397
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,685,422
Number of Sequences: 37866
Number of extensions: 469829
Number of successful extensions: 1707
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 59
Number of HSP's successfully gapped in prelim test: 59
Number of HSP's that attempted gapping in prelim test: 1598
Number of HSP's gapped (non-prelim): 140
length of query: 269
length of database: 18,247,518
effective HSP length: 101
effective length of query: 168
effective length of database: 14,423,052
effective search space: 2423072736
effective search space used: 2423072736
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.