Guide to the Human Genome
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Name: CTLA4 Sequence: fasta or formatted (223aa) NCBI GI: 21361212
Description:

cytotoxic T-lymphocyte-associated protein 4 isoform a precursor

Referenced in:

T cells
Non-Receptor Tyrosine Kinase Pathways

Other entries for this name:
alt prot [174aa] cytotoxic T-lymphocyte-associated protein 4 isoform b precursor
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             7.6         17           2
 C cysteine            4.0          9           1
 D aspartate           3.1          7           2
 E glutamate           4.0          9           1
 F phenylalanine       5.8         13           2
 G glycine             5.8         13           1
 H histidine           0.9          2           1
 I isoleucine          4.9         11           1
 K lysine              4.0          9           2
 L leucine            11.2         25           2
 M methionine          3.6          8           2
 N asparagine          2.7          6           1
 P proline             7.2         16           3
 Q glutamine           4.5         10           1
 R arginine            3.1          7           1
 S serine              6.7         15           2
 T threonine           7.6         17           2
 V valine              7.6         17           2
 W tryptophan          0.9          2           1
 Y tyrosine            4.5         10           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   cytotoxic T-lymphocyte-associated protein 4 isoform ... 
CTLA4                 0.667   cytotoxic T-lymphocyte-associated protein 4 isoform ...
CD28                  0.111   CD28 antigen precursor 
NCR3                  0.042   natural cytotoxicity triggering receptor 3 isoform a...
NCR3                  0.039   natural cytotoxicity triggering receptor 3 isoform ...
NCR3                  0.039   natural cytotoxicity triggering receptor 3 isoform ...
LOC652493             0.025   PREDICTED: similar to pre-B lymphocyte gene 1 [Homo...
MPZL1                 0.023   myelin protein zero-like 1 isoform b 
MPZL1                 0.023   myelin protein zero-like 1 isoform a 
HSPG2                 0.023   heparan sulfate proteoglycan 2 
TMC7                  0.019   transmembrane channel-like 7 isoform b 
TMC7                  0.019   transmembrane channel-like 7 isoform a 
ICOS                  0.016   inducible T-cell co-stimulator precursor 
VSIG1                 0.016   V-set and immunoglobulin domain containing 1 
SCN2B                 0.016   sodium channel, voltage-gated, type II, beta 
IGSF1                 0.016   immunoglobulin superfamily, member 1 isoform 1 [Homo...
LOC100293440          0.012   PREDICTED: similar to Ig lambda chain 
CD79B                 0.012   CD79B antigen isoform 3 precursor 
CD79B                 0.012   CD79B antigen isoform 1 precursor 
NTM                   0.009   neurotrimin isoform 4 
NTM                   0.009   neurotrimin isoform 3 
LOC100293142          0.009   PREDICTED: similar to hCG2040019 
NTM                   0.009   neurotrimin isoform 2 
NTM                   0.009   neurotrimin isoform 1 
HAVCR1                0.009   hepatitis A virus cellular receptor 1 
HAVCR1                0.009   hepatitis A virus cellular receptor 1 
LOC100291786          0.009   PREDICTED: similar to hCG2043206 
LOC440871             0.009   PREDICTED: similar to hCG2043206 
HSDL1                 0.009   hydroxysteroid dehydrogenase like 1 isoform a [Homo...
LOC650405             0.007   PREDICTED: similar to hCG2042707 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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