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Search of human proteins with 4506185
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4506185 proteasome alpha 4 subunit isoform 1 [Homo sapiens]
(261 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|156713442 proteasome alpha 4 subunit isoform 1 [Homo sapiens] 518 e-147
gi|4506185 proteasome alpha 4 subunit isoform 1 [Homo sapiens] 518 e-147
gi|156713444 proteasome alpha 4 subunit isoform 2 [Homo sapiens] 378 e-105
gi|68303563 proteasome alpha 8 subunit isoform 2 [Homo sapiens] 169 3e-42
gi|4506189 proteasome alpha 7 subunit [Homo sapiens] 162 3e-40
gi|68303561 proteasome alpha 8 subunit isoform 1 [Homo sapiens] 162 3e-40
gi|4506181 proteasome subunit alpha type 2 [Homo sapiens] 144 6e-35
gi|68303565 proteasome alpha 8 subunit isoform 3 [Homo sapiens] 137 9e-33
gi|23110944 proteasome alpha 6 subunit [Homo sapiens] 131 5e-31
gi|23110942 proteasome alpha 5 subunit [Homo sapiens] 129 3e-30
gi|4506183 proteasome alpha 3 subunit isoform 1 [Homo sapiens] 111 7e-25
gi|4506179 proteasome alpha 1 subunit isoform 2 [Homo sapiens] 106 2e-23
gi|23110935 proteasome alpha 1 subunit isoform 1 [Homo sapiens] 106 2e-23
gi|23110939 proteasome alpha 3 subunit isoform 2 [Homo sapiens] 105 3e-23
gi|221316716 proteasome alpha 1 subunit isoform 3 [Homo sapiens] 66 3e-11
gi|4506191 proteasome beta 10 subunit proprotein [Homo sapiens] 56 4e-08
gi|169206322 PREDICTED: similar to hCG30646 [Homo sapiens] 47 2e-05
gi|239750562 PREDICTED: similar to hCG30646 [Homo sapiens] 47 2e-05
gi|239744861 PREDICTED: similar to hCG30646 [Homo sapiens] 47 2e-05
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 40 0.003
gi|239750213 PREDICTED: hypothetical protein [Homo sapiens] 39 0.003
gi|225579095 S-phase cyclin A-associated protein in the ER isofo... 37 0.017
gi|169207319 PREDICTED: hypothetical protein [Homo sapiens] 37 0.017
gi|169207756 PREDICTED: hypothetical protein [Homo sapiens] 37 0.017
gi|169207046 PREDICTED: hypothetical protein [Homo sapiens] 37 0.017
gi|225579092 S-phase cyclin A-associated protein in the ER isofo... 37 0.017
gi|11693132 UPF2 regulator of nonsense transcripts homolog [Homo... 37 0.017
gi|18375676 UPF2 regulator of nonsense transcripts homolog [Homo... 37 0.017
gi|32967605 bromodomain adjacent to zinc finger domain, 1A isofo... 37 0.017
gi|32967603 bromodomain adjacent to zinc finger domain, 1A isofo... 37 0.017
>gi|156713442 proteasome alpha 4 subunit isoform 1 [Homo sapiens]
Length = 261
Score = 518 bits (1334), Expect = e-147
Identities = 261/261 (100%), Positives = 261/261 (100%)
Query: 1 MSRRYDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVF 60
MSRRYDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVF
Sbjct: 1 MSRRYDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVF 60
Query: 61 FSEKIYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQA 120
FSEKIYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQA
Sbjct: 61 FSEKIYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQA 120
Query: 121 YTQFGGKRPFGVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYK 180
YTQFGGKRPFGVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYK
Sbjct: 121 YTQFGGKRPFGVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYK 180
Query: 181 EGEMTLKSALALAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKH 240
EGEMTLKSALALAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKH
Sbjct: 181 EGEMTLKSALALAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKH 240
Query: 241 EEEEAKAEREKKEKEQKEKDK 261
EEEEAKAEREKKEKEQKEKDK
Sbjct: 241 EEEEAKAEREKKEKEQKEKDK 261
>gi|4506185 proteasome alpha 4 subunit isoform 1 [Homo sapiens]
Length = 261
Score = 518 bits (1334), Expect = e-147
Identities = 261/261 (100%), Positives = 261/261 (100%)
Query: 1 MSRRYDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVF 60
MSRRYDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVF
Sbjct: 1 MSRRYDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVF 60
Query: 61 FSEKIYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQA 120
FSEKIYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQA
Sbjct: 61 FSEKIYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQA 120
Query: 121 YTQFGGKRPFGVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYK 180
YTQFGGKRPFGVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYK
Sbjct: 121 YTQFGGKRPFGVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYK 180
Query: 181 EGEMTLKSALALAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKH 240
EGEMTLKSALALAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKH
Sbjct: 181 EGEMTLKSALALAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKH 240
Query: 241 EEEEAKAEREKKEKEQKEKDK 261
EEEEAKAEREKKEKEQKEKDK
Sbjct: 241 EEEEAKAEREKKEKEQKEKDK 261
>gi|156713444 proteasome alpha 4 subunit isoform 2 [Homo sapiens]
Length = 190
Score = 378 bits (970), Expect = e-105
Identities = 190/190 (100%), Positives = 190/190 (100%)
Query: 72 MACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPFG 131
MACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPFG
Sbjct: 1 MACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPFG 60
Query: 132 VSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKEGEMTLKSALA 191
VSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKEGEMTLKSALA
Sbjct: 61 VSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKEGEMTLKSALA 120
Query: 192 LAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKHEEEEAKAEREK 251
LAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKHEEEEAKAEREK
Sbjct: 121 LAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKHEEEEAKAEREK 180
Query: 252 KEKEQKEKDK 261
KEKEQKEKDK
Sbjct: 181 KEKEQKEKDK 190
>gi|68303563 proteasome alpha 8 subunit isoform 2 [Homo sapiens]
Length = 250
Score = 169 bits (427), Expect = 3e-42
Identities = 93/255 (36%), Positives = 151/255 (59%), Gaps = 8/255 (3%)
Query: 1 MSRRYDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVF 60
M+ RYD T+FSP+G L+QVEYA EA+ T +GI + V+L E++++ KL DE
Sbjct: 1 MASRYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGIRGTNIVVLGVEKKSVAKLQDERT 60
Query: 61 FSEKIYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQA 120
KI L++ + + AG+T+DA V+ N R+ Q + L ++P+ E + + +KQ
Sbjct: 61 V-RKICALDDHVCMAFAGLTADARVVINRARVECQSHKLTVEDPVTVEYITRFIATLKQK 119
Query: 121 YTQFGGKRPFGVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYK 180
YTQ G+RPFG+S L +G+D +LYQ+DPSG Y WKA IG ++ L+++Y
Sbjct: 120 YTQSNGRRPFGISALIVGFDDDGISRLYQTDPSGTYHAWKANAIGRSAKTVREFLEKNYT 179
Query: 181 EGEMTLKS-ALALAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKK 239
E + S A+ LAIK L ++V + + +E+A + R +++ KEVE + +
Sbjct: 180 EDAIASDSEAIKLAIKAL---LEVVQSGGKNIELAIIRRNQ---PLKMFSAKEVELYVTE 233
Query: 240 HEEEEAKAEREKKEK 254
E+E+ +AE++K +K
Sbjct: 234 IEKEKEEAEKKKSKK 248
>gi|4506189 proteasome alpha 7 subunit [Homo sapiens]
Length = 248
Score = 162 bits (410), Expect = 3e-40
Identities = 86/251 (34%), Positives = 149/251 (59%), Gaps = 8/251 (3%)
Query: 5 YDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVFFSEK 64
YD T+FSP+G L+QVEYA EA+ T +G+ D V+L E++++ KL DE K
Sbjct: 3 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGRDIVVLGVEKKSVAKLQDERTV-RK 61
Query: 65 IYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQF 124
I L++++ + AG+T+DA ++ N R+ Q + L ++P+ E + + +KQ YTQ
Sbjct: 62 ICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQS 121
Query: 125 GGKRPFGVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDY-KEGE 183
G+RPFG+S L +G+D +LYQ+DPSG Y WKA IG + + L+++Y E
Sbjct: 122 NGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDEAI 181
Query: 184 MTLKSALALAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKHEEE 243
T + L IK L ++V + + +E+A + R+ +++L +E+E+ + + E+E
Sbjct: 182 ETDDLTIKLVIKAL---LEVVQSGGKNIELAVMRRDQS---LKILNPEEIEKYVAEIEKE 235
Query: 244 EAKAEREKKEK 254
+ + E++K++K
Sbjct: 236 KEENEKKKQKK 246
>gi|68303561 proteasome alpha 8 subunit isoform 1 [Homo sapiens]
Length = 256
Score = 162 bits (410), Expect = 3e-40
Identities = 93/261 (35%), Positives = 151/261 (57%), Gaps = 14/261 (5%)
Query: 1 MSRRYDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVF 60
M+ RYD T+FSP+G L+QVEYA EA+ T +GI + V+L E++++ KL DE
Sbjct: 1 MASRYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGIRGTNIVVLGVEKKSVAKLQDERT 60
Query: 61 FSEKIYKLNEDMACSVA------GITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTAL 114
KI L++ + + A G+T+DA V+ N R+ Q + L ++P+ E + +
Sbjct: 61 V-RKICALDDHVCMAFAVLTIFIGLTADARVVINRARVECQSHKLTVEDPVTVEYITRFI 119
Query: 115 CDIKQAYTQFGGKRPFGVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSM 174
+KQ YTQ G+RPFG+S L +G+D +LYQ+DPSG Y WKA IG ++
Sbjct: 120 ATLKQKYTQSNGRRPFGISALIVGFDDDGISRLYQTDPSGTYHAWKANAIGRSAKTVREF 179
Query: 175 LKQDYKEGEMTLKS-ALALAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEV 233
L+++Y E + S A+ LAIK L ++V + + +E+A + R +++ KEV
Sbjct: 180 LEKNYTEDAIASDSEAIKLAIKAL---LEVVQSGGKNIELAIIRRNQ---PLKMFSAKEV 233
Query: 234 EQLIKKHEEEEAKAEREKKEK 254
E + + E+E+ +AE++K +K
Sbjct: 234 ELYVTEIEKEKEEAEKKKSKK 254
>gi|4506181 proteasome subunit alpha type 2 [Homo sapiens]
Length = 234
Score = 144 bits (364), Expect = 6e-35
Identities = 82/211 (38%), Positives = 123/211 (58%), Gaps = 4/211 (1%)
Query: 3 RRYDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVFFS 62
R Y T FSP G+L Q+EYA+ A+ +GI A +GV+LA E++ L DE
Sbjct: 4 RGYSFSLTTFSPSGKLVQIEYALAAVAGGAPSVGIKAANGVVLATEKKQKSILYDERSV- 62
Query: 63 EKIYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYT 122
K+ + + + +G+ D VL + R +AQ+Y L YQEPIP QLV + + Q YT
Sbjct: 63 HKVEPITKHIGLVYSGMGPDYRVLVHRARKLAQQYYLVYQEPIPTAQLVQRVASVMQEYT 122
Query: 123 QFGGKRPFGVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKEG 182
Q GG RPFGVSLL GW++ + L+QSDPSG Y WKAT +G N + L++ Y E
Sbjct: 123 QSGGVRPFGVSLLICGWNEGRPY-LFQSDPSGAYFAWKATAMGKNYVNGKTFLEKRYNE- 180
Query: 183 EMTLKSALALAIKVLNKTMDVSKLSAEKVEI 213
++ L+ A+ AI L ++ + +++ + +E+
Sbjct: 181 DLELEDAIHTAILTLKESFE-GQMTEDNIEV 210
>gi|68303565 proteasome alpha 8 subunit isoform 3 [Homo sapiens]
Length = 212
Score = 137 bits (345), Expect = 9e-33
Identities = 82/255 (32%), Positives = 130/255 (50%), Gaps = 46/255 (18%)
Query: 1 MSRRYDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVF 60
M+ RYD T+FSP+G L+QVEYA EA+ T +GI
Sbjct: 1 MASRYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGI----------------------- 37
Query: 61 FSEKIYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQA 120
G+T+DA V+ N R+ Q + L ++P+ E + + +KQ
Sbjct: 38 ----------------RGLTADARVVINRARVECQSHKLTVEDPVTVEYITRFIATLKQK 81
Query: 121 YTQFGGKRPFGVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYK 180
YTQ G+RPFG+S L +G+D +LYQ+DPSG Y WKA IG ++ L+++Y
Sbjct: 82 YTQSNGRRPFGISALIVGFDDDGISRLYQTDPSGTYHAWKANAIGRSAKTVREFLEKNYT 141
Query: 181 EGEMTLKS-ALALAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKK 239
E + S A+ LAIK L ++V + + +E+A + R +++ KEVE + +
Sbjct: 142 EDAIASDSEAIKLAIKAL---LEVVQSGGKNIELAIIRRNQ---PLKMFSAKEVELYVTE 195
Query: 240 HEEEEAKAEREKKEK 254
E+E+ +AE++K +K
Sbjct: 196 IEKEKEEAEKKKSKK 210
>gi|23110944 proteasome alpha 6 subunit [Homo sapiens]
Length = 246
Score = 131 bits (330), Expect = 5e-31
Identities = 78/235 (33%), Positives = 125/235 (53%), Gaps = 6/235 (2%)
Query: 2 SRRYDSRTTIFSPEGRLYQVEYAMEAIGHAG-TCLGILANDGVLLAAERRNIHKLLDEVF 60
S +D TIFSPEGRLYQVEYA +AI G T + + D ++ +++ KLLD
Sbjct: 6 SAGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDSST 65
Query: 61 FSEKIYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQA 120
+ ++K+ E++ C + G+T+D+ R A + +Y IP + L + DI Q
Sbjct: 66 VTH-LFKITENIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQV 124
Query: 121 YTQFGGKRPFGVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSML-KQDY 179
YTQ RP G ++ IG D+ G Q+Y+ DP+G Y G+KAT G + S L K+
Sbjct: 125 YTQNAEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKVK 184
Query: 180 KEGEMTLKSALALAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVE 234
K+ + T + + AI L+ + + ++E+ +T EN K R+L + E++
Sbjct: 185 KKFDWTFEQTVETAITCLSTVLSID-FKPSEIEVGVVTVENPK--FRILTEAEID 236
>gi|23110942 proteasome alpha 5 subunit [Homo sapiens]
Length = 241
Score = 129 bits (323), Expect = 3e-30
Identities = 88/242 (36%), Positives = 140/242 (57%), Gaps = 18/242 (7%)
Query: 5 YDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVFFSEK 64
YD FSPEGRL+QVEYA+EAI T +GI ++GV LA E+R I L E EK
Sbjct: 8 YDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGIQTSEGVCLAVEKR-ITSPLMEPSSIEK 66
Query: 65 IYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQF 124
I +++ + C+++G+ +DA L ++ R+ Q + Y E + E + A+ ++ QF
Sbjct: 67 IVEIDAHIGCAMSGLIADAKTLIDKARVETQNHWFTYNETMTVESVTQAVSNLA---LQF 123
Query: 125 GGK--------RPFGVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLK 176
G + RPFGV+LL+ G D+ G QL+ DPSG + A IG+ S A S L+
Sbjct: 124 GEEDADPGAMSRPFGVALLFGGVDEK-GPQLFHMDPSGTFVQCDARAIGSASEGAQSSLQ 182
Query: 177 QDYKEGEMTLKSALALAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQL 236
+ Y + MTLK A+ ++ +L + M+ KL+A +E+AT+ + G+ + ++E+E++
Sbjct: 183 EVYHK-SMTLKEAIKSSLIILKQVME-EKLNATNIELATV--QPGQN-FHMFTKEELEEV 237
Query: 237 IK 238
IK
Sbjct: 238 IK 239
>gi|4506183 proteasome alpha 3 subunit isoform 1 [Homo sapiens]
Length = 255
Score = 111 bits (277), Expect = 7e-25
Identities = 76/258 (29%), Positives = 128/258 (49%), Gaps = 16/258 (6%)
Query: 5 YDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVFFSEK 64
YD + FSP+GR++QVEYAM+A+ ++ T +GI DGV+ E+ + KL +E +++
Sbjct: 8 YDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEE-GSNKR 66
Query: 65 IYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQF 124
++ ++ + +VAG+ +DA L + R A + + IP + L + AYT +
Sbjct: 67 LFNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLY 126
Query: 125 GGKRPFGVSLLYIGWDKHYGFQLYQSDPSG-NYGGWKATCIGNNSAAAVSMLKQDYKEGE 183
RPFG S + + + G QLY DPSG +YG W AA + K K E
Sbjct: 127 SAVRPFGCSFMLGSYSVNDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKLQMK--E 184
Query: 184 MTLKSALALAIKVLNKTMDVSKLSAEKVEIATLTR-ENGKTVIRVLKQKEVEQLIKKHEE 242
MT + + K++ D K A ++E++ + NG+ +++ K
Sbjct: 185 MTCRDIVKEVAKIIYIVHDEVKDKAFELELSWVGELTNGR-----------HEIVPKDIR 233
Query: 243 EEAKAEREKKEKEQKEKD 260
EEA+ ++ KE+ E D
Sbjct: 234 EEAEKYAKESLKEEDESD 251
>gi|4506179 proteasome alpha 1 subunit isoform 2 [Homo sapiens]
Length = 263
Score = 106 bits (264), Expect = 2e-23
Identities = 75/259 (28%), Positives = 133/259 (51%), Gaps = 10/259 (3%)
Query: 4 RYDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVFFSE 63
+YD+ T++SP+GR++Q+EYAMEA+ +G+ + +L A +R +L +
Sbjct: 5 QYDNDVTVWSPQGRIHQIEYAMEAVKQGSATVGLKSKTHAVLVALKRAQSELAAH---QK 61
Query: 64 KIYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQ 123
KI ++ + S+AG+T+DA +L N +R + P+P +LV+ + Q TQ
Sbjct: 62 KILHVDNHIGISIAGLTADARLLCNFMRQECLDSRFVFDRPLPVSRLVSLIGSKTQIPTQ 121
Query: 124 FGGKRPFGVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKE-G 182
G+RP+GV LL G+D G ++Q+ PS NY +A IG S +A + L++ E
Sbjct: 122 RYGRRPYGVGLLIAGYD-DMGPHIFQTCPSANYFDCRAMSIGARSQSARTYLERHMSEFM 180
Query: 183 EMTLKSALALAIKVLNKTMDVSK-LSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKHE 241
E L + ++ L +T+ + L+ + V I + ++ T + +V ++ E
Sbjct: 181 ECNLNELVKHGLRALRETLPAEQDLTTKNVSIGIVGKDLEFT---IYDDDDVSPFLEGLE 237
Query: 242 EE-EAKAEREKKEKEQKEK 259
E + KA+ + E EK
Sbjct: 238 ERPQRKAQPAQPADEPAEK 256
>gi|23110935 proteasome alpha 1 subunit isoform 1 [Homo sapiens]
Length = 269
Score = 106 bits (264), Expect = 2e-23
Identities = 75/259 (28%), Positives = 133/259 (51%), Gaps = 10/259 (3%)
Query: 4 RYDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVFFSE 63
+YD+ T++SP+GR++Q+EYAMEA+ +G+ + +L A +R +L +
Sbjct: 11 QYDNDVTVWSPQGRIHQIEYAMEAVKQGSATVGLKSKTHAVLVALKRAQSELAAH---QK 67
Query: 64 KIYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQ 123
KI ++ + S+AG+T+DA +L N +R + P+P +LV+ + Q TQ
Sbjct: 68 KILHVDNHIGISIAGLTADARLLCNFMRQECLDSRFVFDRPLPVSRLVSLIGSKTQIPTQ 127
Query: 124 FGGKRPFGVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKE-G 182
G+RP+GV LL G+D G ++Q+ PS NY +A IG S +A + L++ E
Sbjct: 128 RYGRRPYGVGLLIAGYD-DMGPHIFQTCPSANYFDCRAMSIGARSQSARTYLERHMSEFM 186
Query: 183 EMTLKSALALAIKVLNKTMDVSK-LSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKHE 241
E L + ++ L +T+ + L+ + V I + ++ T + +V ++ E
Sbjct: 187 ECNLNELVKHGLRALRETLPAEQDLTTKNVSIGIVGKDLEFT---IYDDDDVSPFLEGLE 243
Query: 242 EE-EAKAEREKKEKEQKEK 259
E + KA+ + E EK
Sbjct: 244 ERPQRKAQPAQPADEPAEK 262
>gi|23110939 proteasome alpha 3 subunit isoform 2 [Homo sapiens]
Length = 248
Score = 105 bits (263), Expect = 3e-23
Identities = 76/258 (29%), Positives = 127/258 (49%), Gaps = 23/258 (8%)
Query: 5 YDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVFFSEK 64
YD + FSP+GR++QVEYAM+A+ ++ T +GI DGV+ E+ + KL +E +++
Sbjct: 8 YDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEE-GSNKR 66
Query: 65 IYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQF 124
++ ++ + +VAG+ +DA L + R A + + IP + L + AYT +
Sbjct: 67 LFNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLY 126
Query: 125 GGKRPFGVSLLYIGWDKHYGFQLYQSDPSG-NYGGWKATCIGNNSAAAVSMLKQDYKEGE 183
RPFG S+ + G QLY DPSG +YG W AA + K K E
Sbjct: 127 SAVRPFGCSV-------NDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKLQMK--E 177
Query: 184 MTLKSALALAIKVLNKTMDVSKLSAEKVEIATLTR-ENGKTVIRVLKQKEVEQLIKKHEE 242
MT + + K++ D K A ++E++ + NG+ +++ K
Sbjct: 178 MTCRDIVKEVAKIIYIVHDEVKDKAFELELSWVGELTNGR-----------HEIVPKDIR 226
Query: 243 EEAKAEREKKEKEQKEKD 260
EEA+ ++ KE+ E D
Sbjct: 227 EEAEKYAKESLKEEDESD 244
>gi|221316716 proteasome alpha 1 subunit isoform 3 [Homo sapiens]
Length = 130
Score = 66.2 bits (160), Expect = 3e-11
Identities = 34/111 (30%), Positives = 63/111 (56%), Gaps = 3/111 (2%)
Query: 4 RYDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVFFSE 63
+YD+ T++SP+GR++Q+EYAMEA+ +G+ + +L A +R +L +
Sbjct: 5 QYDNDVTVWSPQGRIHQIEYAMEAVKQGSATVGLKSKTHAVLVALKRAQSEL---AAHQK 61
Query: 64 KIYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTAL 114
KI ++ + S+AG+T+DA +L N +R + P+P +LV+ +
Sbjct: 62 KILHVDNHIGISIAGLTADARLLCNFMRQECLDSRFVFDRPLPVSRLVSLI 112
>gi|4506191 proteasome beta 10 subunit proprotein [Homo sapiens]
Length = 273
Score = 55.8 bits (133), Expect = 4e-08
Identities = 50/190 (26%), Positives = 89/190 (46%), Gaps = 7/190 (3%)
Query: 33 TCLGILANDGVLLAAERRNIHKLLDEVFFSEKIYKLNEDMACSVAGITSDANVLTNELRL 92
T G++ DGV+L A+ R + + EKI+ + + C AG+ +DA + T R+
Sbjct: 41 TIAGLVFQDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADAEMTT---RM 97
Query: 93 IAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPFGVSLLYIGWDKHYGFQLYQSDP 152
+A + L ++ T ++Q ++ G G SL+ G D G QLY P
Sbjct: 98 VASKMELHALSTGREPRVATVTRILRQTLFRYQGH--VGASLIVGGVDLT-GPQLYGVHP 154
Query: 153 SGNYGGWKATCIGNNSAAAVSMLKQDYKEGEMTLKSALALAIKVLNKTMDVSKLSAEKVE 212
G+Y T +G+ AA+++L +D + MTL++A L ++ + + S V+
Sbjct: 155 HGSYSRLPFTALGSGQDAALAVL-EDRFQPNMTLEAAQGLLVEAVTAGILGDLGSGGNVD 213
Query: 213 IATLTRENGK 222
+T+ K
Sbjct: 214 ACVITKTGAK 223
>gi|169206322 PREDICTED: similar to hCG30646 [Homo sapiens]
Length = 272
Score = 47.0 bits (110), Expect = 2e-05
Identities = 44/176 (25%), Positives = 74/176 (42%), Gaps = 42/176 (23%)
Query: 2 SRRYDSRTTIFSPEGRLYQVEYAMEAIGHAG-TCLGILANDGVLLAAERRNIHKLLDEVF 60
S +D IFSP+ +LYQV+YA +AI G T + + D ++ + KLLD
Sbjct: 90 STGFDRHLIIFSPKVQLYQVQYAFKAINQGGLTSVAVRKKDCAVIVTHKIVPDKLLDS-- 147
Query: 61 FSEKIYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQA 120
++K+ ++ + G+T+D+ ++ QY+ A C
Sbjct: 148 -RTHLFKMTKNTGRVITGVTADSR---------SREQRAQYK---------AANC----K 184
Query: 121 YTQFGGKRPFGVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLK 176
Y F + G ++Y+ D +G Y G+KAT G A + S L+
Sbjct: 185 YNIF----------------EELGPRVYKCDAAGYYCGFKATAAGVKQAESTSFLE 224
>gi|239750562 PREDICTED: similar to hCG30646 [Homo sapiens]
Length = 272
Score = 47.0 bits (110), Expect = 2e-05
Identities = 44/176 (25%), Positives = 74/176 (42%), Gaps = 42/176 (23%)
Query: 2 SRRYDSRTTIFSPEGRLYQVEYAMEAIGHAG-TCLGILANDGVLLAAERRNIHKLLDEVF 60
S +D IFSP+ +LYQV+YA +AI G T + + D ++ + KLLD
Sbjct: 90 STGFDRHLIIFSPKVQLYQVQYAFKAINQGGLTSVAVRKKDCAVIVTHKIVPDKLLDS-- 147
Query: 61 FSEKIYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQA 120
++K+ ++ + G+T+D+ ++ QY+ A C
Sbjct: 148 -RTHLFKMTKNTGRVITGVTADSR---------SREQRAQYK---------AANC----K 184
Query: 121 YTQFGGKRPFGVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLK 176
Y F + G ++Y+ D +G Y G+KAT G A + S L+
Sbjct: 185 YNIF----------------EELGPRVYKCDAAGYYCGFKATAAGVKQAESTSFLE 224
>gi|239744861 PREDICTED: similar to hCG30646 [Homo sapiens]
Length = 272
Score = 47.0 bits (110), Expect = 2e-05
Identities = 44/176 (25%), Positives = 74/176 (42%), Gaps = 42/176 (23%)
Query: 2 SRRYDSRTTIFSPEGRLYQVEYAMEAIGHAG-TCLGILANDGVLLAAERRNIHKLLDEVF 60
S +D IFSP+ +LYQV+YA +AI G T + + D ++ + KLLD
Sbjct: 90 STGFDRHLIIFSPKVQLYQVQYAFKAINQGGLTSVAVRKKDCAVIVTHKIVPDKLLDS-- 147
Query: 61 FSEKIYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQA 120
++K+ ++ + G+T+D+ ++ QY+ A C
Sbjct: 148 -RTHLFKMTKNTGRVITGVTADSR---------SREQRAQYK---------AANC----K 184
Query: 121 YTQFGGKRPFGVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLK 176
Y F + G ++Y+ D +G Y G+KAT G A + S L+
Sbjct: 185 YNIF----------------EELGPRVYKCDAAGYYCGFKATAAGVKQAESTSFLE 224
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 39.7 bits (91), Expect = 0.003
Identities = 28/97 (28%), Positives = 51/97 (52%), Gaps = 13/97 (13%)
Query: 169 AAAVSMLKQDYKEGEMTL----KSALALAIKVLNKTMDVSKLSAEKVEIATLTRENGKTV 224
+AAV ++ +E E + K+A A +K L++ + + + EI RE
Sbjct: 456 SAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIRERERE----- 510
Query: 225 IRVLKQKEVEQLIKKHEEEEAKAEREKKEKEQKEKDK 261
K++E E+ ++K +E+E + EREK + Q+EK+K
Sbjct: 511 ----KEREREKELEKEQEQEREKEREKDRERQQEKEK 543
Score = 31.6 bits (70), Expect = 0.73
Identities = 15/33 (45%), Positives = 23/33 (69%)
Query: 229 KQKEVEQLIKKHEEEEAKAEREKKEKEQKEKDK 261
K+ E EQ ++ E+E K E+EK+ + QKEK+K
Sbjct: 543 KELEKEQEKQREMEKERKQEKEKELERQKEKEK 575
Score = 29.6 bits (65), Expect = 2.8
Identities = 12/33 (36%), Positives = 26/33 (78%)
Query: 229 KQKEVEQLIKKHEEEEAKAEREKKEKEQKEKDK 261
KQ+E+E+ K+ +E+E + ++EK+++ QK K++
Sbjct: 551 KQREMEKERKQEKEKELERQKEKEKELQKMKEQ 583
Score = 28.5 bits (62), Expect = 6.2
Identities = 12/31 (38%), Positives = 23/31 (74%)
Query: 229 KQKEVEQLIKKHEEEEAKAEREKKEKEQKEK 259
+QKE E+ ++K +E+E + E EK+ ++ +EK
Sbjct: 569 RQKEKEKELQKMKEQEKECELEKEREKLEEK 599
>gi|239750213 PREDICTED: hypothetical protein [Homo sapiens]
Length = 248
Score = 39.3 bits (90), Expect = 0.003
Identities = 26/89 (29%), Positives = 46/89 (51%), Gaps = 1/89 (1%)
Query: 173 SMLKQDYKEGEMTLKSALALAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKE 232
S K+ K+ K +K KT K + + + T T++ T + K+KE
Sbjct: 21 SAWKRGRKKKTTKKKKKKKTTMKKKKKTTTKKKTTTKTKKRTTTTKKTTTTTTKE-KEKE 79
Query: 233 VEQLIKKHEEEEAKAEREKKEKEQKEKDK 261
E+ +K +E+E + E+EKK+K++K+K K
Sbjct: 80 KEKEKEKEKEKEKEKEKEKKKKKKKKKKK 108
Score = 37.0 bits (84), Expect = 0.017
Identities = 23/82 (28%), Positives = 42/82 (51%), Gaps = 5/82 (6%)
Query: 180 KEGEMTLKSALALAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKK 239
K+ + T+K K T + + K T T+E K K+KE E+ +K
Sbjct: 36 KKKKTTMKKKKKTTTKKKTTTKTKKRTTTTKKTTTTTTKEKEKE-----KEKEKEKEKEK 90
Query: 240 HEEEEAKAEREKKEKEQKEKDK 261
+E+E + +++KK+K++K+K K
Sbjct: 91 EKEKEKEKKKKKKKKKKKKKKK 112
>gi|225579095 S-phase cyclin A-associated protein in the ER isoform
b [Homo sapiens]
Length = 1154
Score = 37.0 bits (84), Expect = 0.017
Identities = 17/64 (26%), Positives = 36/64 (56%)
Query: 197 LNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKHEEEEAKAEREKKEKEQ 256
LN+ + + E+ + + K + +Q VE+L+ K +E+EA+ E++++EKE+
Sbjct: 406 LNELQEERQRRQEEKQARDEAVQERKRALEAERQARVEELLMKRKEQEARIEQQRQEKEK 465
Query: 257 KEKD 260
+D
Sbjct: 466 ARED 469
>gi|169207319 PREDICTED: hypothetical protein [Homo sapiens]
Length = 828
Score = 37.0 bits (84), Expect = 0.017
Identities = 25/103 (24%), Positives = 51/103 (49%), Gaps = 6/103 (5%)
Query: 159 WKATCIGNNSAAAVSMLKQDYKEGEMTLKSALALAIKVLNKT----MDVSKLSAEKVEIA 214
WK C+ A + +K + + +++A I++LN+T ++S A+ ++
Sbjct: 457 WKMACLRKKHARWTAKIKAEIQAITEKIQNAEVRRIELLNETSFRQQEISGFVAQIEKLT 516
Query: 215 TLTRENGKTVIRVLKQKEVEQLIKKHEEEEAKAEREKKEKEQK 257
T +E K + K+K + + + K+EE K + KEKE++
Sbjct: 517 TELKEEEKAFVN--KEKMLMKELSKYEEIFVKETQINKEKEEE 557
>gi|169207756 PREDICTED: hypothetical protein [Homo sapiens]
Length = 828
Score = 37.0 bits (84), Expect = 0.017
Identities = 25/103 (24%), Positives = 51/103 (49%), Gaps = 6/103 (5%)
Query: 159 WKATCIGNNSAAAVSMLKQDYKEGEMTLKSALALAIKVLNKT----MDVSKLSAEKVEIA 214
WK C+ A + +K + + +++A I++LN+T ++S A+ ++
Sbjct: 457 WKMACLRKKHARWTAKIKAEIQAITEKIQNAEVRRIELLNETSFRQQEISGFVAQIEKLT 516
Query: 215 TLTRENGKTVIRVLKQKEVEQLIKKHEEEEAKAEREKKEKEQK 257
T +E K + K+K + + + K+EE K + KEKE++
Sbjct: 517 TELKEEEKAFVN--KEKMLMKELSKYEEIFVKETQINKEKEEE 557
>gi|169207046 PREDICTED: hypothetical protein [Homo sapiens]
Length = 828
Score = 37.0 bits (84), Expect = 0.017
Identities = 25/103 (24%), Positives = 51/103 (49%), Gaps = 6/103 (5%)
Query: 159 WKATCIGNNSAAAVSMLKQDYKEGEMTLKSALALAIKVLNKT----MDVSKLSAEKVEIA 214
WK C+ A + +K + + +++A I++LN+T ++S A+ ++
Sbjct: 457 WKMACLRKKHARWTAKIKAEIQAITEKIQNAEVRRIELLNETSFRQQEISGFVAQIEKLT 516
Query: 215 TLTRENGKTVIRVLKQKEVEQLIKKHEEEEAKAEREKKEKEQK 257
T +E K + K+K + + + K+EE K + KEKE++
Sbjct: 517 TELKEEEKAFVN--KEKMLMKELSKYEEIFVKETQINKEKEEE 557
>gi|225579092 S-phase cyclin A-associated protein in the ER isoform
a [Homo sapiens]
Length = 1400
Score = 37.0 bits (84), Expect = 0.017
Identities = 17/64 (26%), Positives = 36/64 (56%)
Query: 197 LNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKHEEEEAKAEREKKEKEQ 256
LN+ + + E+ + + K + +Q VE+L+ K +E+EA+ E++++EKE+
Sbjct: 652 LNELQEERQRRQEEKQARDEAVQERKRALEAERQARVEELLMKRKEQEARIEQQRQEKEK 711
Query: 257 KEKD 260
+D
Sbjct: 712 ARED 715
>gi|11693132 UPF2 regulator of nonsense transcripts homolog [Homo
sapiens]
Length = 1272
Score = 37.0 bits (84), Expect = 0.017
Identities = 23/60 (38%), Positives = 37/60 (61%), Gaps = 2/60 (3%)
Query: 202 DVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKHEEEEAKAEREKKEKEQKEKDK 261
D KL+A+K + E+ K + K+K+ ++ KK +EE+ KAE E K+KE++EK K
Sbjct: 39 DDIKLTAKKE--VSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKK 96
Score = 35.0 bits (79), Expect = 0.066
Identities = 26/97 (26%), Positives = 46/97 (47%), Gaps = 5/97 (5%)
Query: 163 CIGNNSAAAVSMLKQDYKEGEMTLKSALALAIKVLNKTMDVSKLSAEKVEIATLTRENGK 222
C + ++ K D K +T K ++ A + K ++ K E E E K
Sbjct: 25 CSERRTVSSKERPKDDIK---LTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVK 81
Query: 223 TVIRVLKQKEVEQLIKKHEEEEAKAEREKKEKEQKEK 259
K++E E+ KKH+EEE K + E+ +++Q+E+
Sbjct: 82 AEEESKKKEEEEK--KKHQEEERKKQEEQAKRQQEEE 116
Score = 29.6 bits (65), Expect = 2.8
Identities = 21/68 (30%), Positives = 34/68 (50%), Gaps = 3/68 (4%)
Query: 197 LNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKE---VEQLIKKHEEEEAKAEREKKE 253
L +VSK +K + + + R K +E E+ KK EEEE K +E++
Sbjct: 43 LTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEER 102
Query: 254 KEQKEKDK 261
K+Q+E+ K
Sbjct: 103 KKQEEQAK 110
Score = 28.5 bits (62), Expect = 6.2
Identities = 13/45 (28%), Positives = 29/45 (64%)
Query: 217 TRENGKTVIRVLKQKEVEQLIKKHEEEEAKAEREKKEKEQKEKDK 261
++E K I++ +KEV + + ++ +R+K++KE+K+KD+
Sbjct: 33 SKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDE 77
>gi|18375676 UPF2 regulator of nonsense transcripts homolog [Homo
sapiens]
Length = 1272
Score = 37.0 bits (84), Expect = 0.017
Identities = 23/60 (38%), Positives = 37/60 (61%), Gaps = 2/60 (3%)
Query: 202 DVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKHEEEEAKAEREKKEKEQKEKDK 261
D KL+A+K + E+ K + K+K+ ++ KK +EE+ KAE E K+KE++EK K
Sbjct: 39 DDIKLTAKKE--VSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKK 96
Score = 35.0 bits (79), Expect = 0.066
Identities = 26/97 (26%), Positives = 46/97 (47%), Gaps = 5/97 (5%)
Query: 163 CIGNNSAAAVSMLKQDYKEGEMTLKSALALAIKVLNKTMDVSKLSAEKVEIATLTRENGK 222
C + ++ K D K +T K ++ A + K ++ K E E E K
Sbjct: 25 CSERRTVSSKERPKDDIK---LTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVK 81
Query: 223 TVIRVLKQKEVEQLIKKHEEEEAKAEREKKEKEQKEK 259
K++E E+ KKH+EEE K + E+ +++Q+E+
Sbjct: 82 AEEESKKKEEEEK--KKHQEEERKKQEEQAKRQQEEE 116
Score = 29.6 bits (65), Expect = 2.8
Identities = 21/68 (30%), Positives = 34/68 (50%), Gaps = 3/68 (4%)
Query: 197 LNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKE---VEQLIKKHEEEEAKAEREKKE 253
L +VSK +K + + + R K +E E+ KK EEEE K +E++
Sbjct: 43 LTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEER 102
Query: 254 KEQKEKDK 261
K+Q+E+ K
Sbjct: 103 KKQEEQAK 110
Score = 28.5 bits (62), Expect = 6.2
Identities = 13/45 (28%), Positives = 29/45 (64%)
Query: 217 TRENGKTVIRVLKQKEVEQLIKKHEEEEAKAEREKKEKEQKEKDK 261
++E K I++ +KEV + + ++ +R+K++KE+K+KD+
Sbjct: 33 SKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDE 77
>gi|32967605 bromodomain adjacent to zinc finger domain, 1A isoform
b [Homo sapiens]
Length = 1524
Score = 37.0 bits (84), Expect = 0.017
Identities = 31/105 (29%), Positives = 49/105 (46%), Gaps = 15/105 (14%)
Query: 172 VSMLKQDYKEGEMTLKSALALAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQK 231
+ + ++D + TL S + A K +K + ++ + E A L RE + K+K
Sbjct: 283 IHISQEDNVANKQTLASYRSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKKEK 342
Query: 232 E--------------VEQLIKKHEEEEAKAEREK-KEKEQKEKDK 261
E E+L KK E+E K EREK +EK ++EK K
Sbjct: 343 EDKEKKREELKKIVEEERLKKKEEKERLKVEREKEREKLREEKRK 387
>gi|32967603 bromodomain adjacent to zinc finger domain, 1A isoform
a [Homo sapiens]
Length = 1556
Score = 37.0 bits (84), Expect = 0.017
Identities = 31/105 (29%), Positives = 49/105 (46%), Gaps = 15/105 (14%)
Query: 172 VSMLKQDYKEGEMTLKSALALAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQK 231
+ + ++D + TL S + A K +K + ++ + E A L RE + K+K
Sbjct: 283 IHISQEDNVANKQTLASYRSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKKEK 342
Query: 232 E--------------VEQLIKKHEEEEAKAEREK-KEKEQKEKDK 261
E E+L KK E+E K EREK +EK ++EK K
Sbjct: 343 EDKEKKREELKKIVEEERLKKKEEKERLKVEREKEREKLREEKRK 387
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.132 0.370
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,985,995
Number of Sequences: 37866
Number of extensions: 384765
Number of successful extensions: 8748
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 209
Number of HSP's successfully gapped in prelim test: 159
Number of HSP's that attempted gapping in prelim test: 5339
Number of HSP's gapped (non-prelim): 2661
length of query: 261
length of database: 18,247,518
effective HSP length: 100
effective length of query: 161
effective length of database: 14,460,918
effective search space: 2328207798
effective search space used: 2328207798
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.