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Search of human proteins with 4505917
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4505917 exosome component 10 isoform 2 [Homo sapiens]
(860 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4505917 exosome component 10 isoform 2 [Homo sapiens] 1736 0.0
gi|50301240 exosome component 10 isoform 1 [Homo sapiens] 1722 0.0
gi|104526627 triadin [Homo sapiens] 46 2e-04
gi|145279204 exonuclease 3'-5' domain containing 3 [Homo sapiens] 44 5e-04
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 42 0.002
gi|56961680 coiled-coil domain containing 147 [Homo sapiens] 40 0.007
gi|38788260 bromodomain PHD finger transcription factor isoform ... 40 0.012
gi|38788274 bromodomain PHD finger transcription factor isoform ... 40 0.012
gi|239748665 PREDICTED: hypothetical protein [Homo sapiens] 39 0.021
gi|239742690 PREDICTED: hypothetical protein [Homo sapiens] 39 0.021
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] 39 0.021
gi|87116683 proline/serine-rich coiled-coil 2 [Homo sapiens] 39 0.027
gi|189409142 telomeric repeat binding factor 1 isoform 1 [Homo s... 38 0.035
gi|95147555 microtubule-associated protein 1A [Homo sapiens] 38 0.035
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 38 0.046
gi|4506467 radixin [Homo sapiens] 38 0.046
gi|54112403 chromodomain helicase DNA binding protein 7 [Homo sa... 38 0.046
gi|68508961 centromere protein C 1 [Homo sapiens] 38 0.046
gi|154354979 myosin X [Homo sapiens] 38 0.046
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 38 0.046
gi|90093355 jumonji C domain containing histone demethylase 1 ho... 37 0.060
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 37 0.060
gi|187761317 tet oncogene family member 2 isoform a [Homo sapiens] 37 0.10
gi|11067749 bromodomain containing protein 3 [Homo sapiens] 37 0.10
gi|27734775 hypothetical protein LOC286499 [Homo sapiens] 37 0.10
gi|110349719 titin isoform N2-A [Homo sapiens] 36 0.13
gi|92859701 myosin VI [Homo sapiens] 36 0.13
gi|126090663 zinc finger homeodomain 4 [Homo sapiens] 36 0.13
gi|110349717 titin isoform novex-2 [Homo sapiens] 36 0.17
gi|110349713 titin isoform novex-1 [Homo sapiens] 36 0.17
>gi|4505917 exosome component 10 isoform 2 [Homo sapiens]
Length = 860
Score = 1736 bits (4495), Expect = 0.0
Identities = 860/860 (100%), Positives = 860/860 (100%)
Query: 1 MAPPSTREPRVLSATSATKSDGEMVLPGFPDADSFVKFALGSVVAVTKASGGLPQFGDEY 60
MAPPSTREPRVLSATSATKSDGEMVLPGFPDADSFVKFALGSVVAVTKASGGLPQFGDEY
Sbjct: 1 MAPPSTREPRVLSATSATKSDGEMVLPGFPDADSFVKFALGSVVAVTKASGGLPQFGDEY 60
Query: 61 DFYRSFPGFQAFCETQGDRLLQCMSRVMQYHGCRSNIKDRSKVTELEDKFDLLVDANDVI 120
DFYRSFPGFQAFCETQGDRLLQCMSRVMQYHGCRSNIKDRSKVTELEDKFDLLVDANDVI
Sbjct: 61 DFYRSFPGFQAFCETQGDRLLQCMSRVMQYHGCRSNIKDRSKVTELEDKFDLLVDANDVI 120
Query: 121 LERVGILLDEASGVNKNQQPVLPAGLQVPKTVVSSWNRKAAEYGKKAKSETFRLLHAKNI 180
LERVGILLDEASGVNKNQQPVLPAGLQVPKTVVSSWNRKAAEYGKKAKSETFRLLHAKNI
Sbjct: 121 LERVGILLDEASGVNKNQQPVLPAGLQVPKTVVSSWNRKAAEYGKKAKSETFRLLHAKNI 180
Query: 181 IRPQLKFREKIDNSNTPFLPKIFIKPNAQKPLPQALSKERRERPQDRPEDLDVPPALADF 240
IRPQLKFREKIDNSNTPFLPKIFIKPNAQKPLPQALSKERRERPQDRPEDLDVPPALADF
Sbjct: 181 IRPQLKFREKIDNSNTPFLPKIFIKPNAQKPLPQALSKERRERPQDRPEDLDVPPALADF 240
Query: 241 IHQQRTQQVEQDMFAHPYQYELNHFTPADAVLQKPQPQLYRPIEETPCHFISSLDELVEL 300
IHQQRTQQVEQDMFAHPYQYELNHFTPADAVLQKPQPQLYRPIEETPCHFISSLDELVEL
Sbjct: 241 IHQQRTQQVEQDMFAHPYQYELNHFTPADAVLQKPQPQLYRPIEETPCHFISSLDELVEL 300
Query: 301 NEKLLNCQEFAVDLEHHSYRSFLGLTCLMQISTRTEDFIIDTLELRSDMYILNESLTDPA 360
NEKLLNCQEFAVDLEHHSYRSFLGLTCLMQISTRTEDFIIDTLELRSDMYILNESLTDPA
Sbjct: 301 NEKLLNCQEFAVDLEHHSYRSFLGLTCLMQISTRTEDFIIDTLELRSDMYILNESLTDPA 360
Query: 361 IVKVFHGADSDIEWLQKDFGLYVVNMFDTHQAARLLNLGRHSLDHLLKLYCNVDSNKQYQ 420
IVKVFHGADSDIEWLQKDFGLYVVNMFDTHQAARLLNLGRHSLDHLLKLYCNVDSNKQYQ
Sbjct: 361 IVKVFHGADSDIEWLQKDFGLYVVNMFDTHQAARLLNLGRHSLDHLLKLYCNVDSNKQYQ 420
Query: 421 LADWRIRPLPEEMLSYARDDTHYLLYIYDKMRLEMWERGNGQPVQLQVVWQRSRDICLKK 480
LADWRIRPLPEEMLSYARDDTHYLLYIYDKMRLEMWERGNGQPVQLQVVWQRSRDICLKK
Sbjct: 421 LADWRIRPLPEEMLSYARDDTHYLLYIYDKMRLEMWERGNGQPVQLQVVWQRSRDICLKK 480
Query: 481 FIKPIFTDESYLELYRKQKKHLNTQQLTAFQLLFAWRDKTARREDESYGYVLPNHMMLKI 540
FIKPIFTDESYLELYRKQKKHLNTQQLTAFQLLFAWRDKTARREDESYGYVLPNHMMLKI
Sbjct: 481 FIKPIFTDESYLELYRKQKKHLNTQQLTAFQLLFAWRDKTARREDESYGYVLPNHMMLKI 540
Query: 541 AEELPKEPQGIIACCNPVPPLVRQQINEMHLLIQQAREMPLLKSEVAAGVKKSGPLPSAE 600
AEELPKEPQGIIACCNPVPPLVRQQINEMHLLIQQAREMPLLKSEVAAGVKKSGPLPSAE
Sbjct: 541 AEELPKEPQGIIACCNPVPPLVRQQINEMHLLIQQAREMPLLKSEVAAGVKKSGPLPSAE 600
Query: 601 RLENVLFGPHDCSHAPPDGYPIIPTSGSVPVQKQASLFPDEKEDNLLGTTCLIATAVITL 660
RLENVLFGPHDCSHAPPDGYPIIPTSGSVPVQKQASLFPDEKEDNLLGTTCLIATAVITL
Sbjct: 601 RLENVLFGPHDCSHAPPDGYPIIPTSGSVPVQKQASLFPDEKEDNLLGTTCLIATAVITL 660
Query: 661 FNEPSAEDSKKGPLTVAQKKAQNIMESFENPFRMISNRWKLAQVQVQKDSKEAVKKKAAE 720
FNEPSAEDSKKGPLTVAQKKAQNIMESFENPFRMISNRWKLAQVQVQKDSKEAVKKKAAE
Sbjct: 661 FNEPSAEDSKKGPLTVAQKKAQNIMESFENPFRMISNRWKLAQVQVQKDSKEAVKKKAAE 720
Query: 721 QTAAREQAKEACKAAAEQAISVRQQVVLENAAKKRERATSDPRTTEQKQEKKRLKISKKP 780
QTAAREQAKEACKAAAEQAISVRQQVVLENAAKKRERATSDPRTTEQKQEKKRLKISKKP
Sbjct: 721 QTAAREQAKEACKAAAEQAISVRQQVVLENAAKKRERATSDPRTTEQKQEKKRLKISKKP 780
Query: 781 KDPEPPEKEFTPYDYSQSDFKAFAGNSKSKVSSQFDPNKQTPSGKKCIAAKKIKQSVGNK 840
KDPEPPEKEFTPYDYSQSDFKAFAGNSKSKVSSQFDPNKQTPSGKKCIAAKKIKQSVGNK
Sbjct: 781 KDPEPPEKEFTPYDYSQSDFKAFAGNSKSKVSSQFDPNKQTPSGKKCIAAKKIKQSVGNK 840
Query: 841 SMSFPTGKSDRGFRYNWPQR 860
SMSFPTGKSDRGFRYNWPQR
Sbjct: 841 SMSFPTGKSDRGFRYNWPQR 860
>gi|50301240 exosome component 10 isoform 1 [Homo sapiens]
Length = 885
Score = 1722 bits (4459), Expect = 0.0
Identities = 860/885 (97%), Positives = 860/885 (97%), Gaps = 25/885 (2%)
Query: 1 MAPPSTREPRVLSATSATKSDGEMVLPGFPDADSFVKFALGSVVAVTKASGGLPQFGDEY 60
MAPPSTREPRVLSATSATKSDGEMVLPGFPDADSFVKFALGSVVAVTKASGGLPQFGDEY
Sbjct: 1 MAPPSTREPRVLSATSATKSDGEMVLPGFPDADSFVKFALGSVVAVTKASGGLPQFGDEY 60
Query: 61 DFYRSFPGFQAFCETQGDRLLQCMSRVMQYHGCRSNIKDRSKVTELEDKFDLLVDANDVI 120
DFYRSFPGFQAFCETQGDRLLQCMSRVMQYHGCRSNIKDRSKVTELEDKFDLLVDANDVI
Sbjct: 61 DFYRSFPGFQAFCETQGDRLLQCMSRVMQYHGCRSNIKDRSKVTELEDKFDLLVDANDVI 120
Query: 121 LERVGILLDEASGVNKNQQPVLPAGLQVPKTVVSSWNRKAAEYGKKAKSETFRLLHAKNI 180
LERVGILLDEASGVNKNQQPVLPAGLQVPKTVVSSWNRKAAEYGKKAKSETFRLLHAKNI
Sbjct: 121 LERVGILLDEASGVNKNQQPVLPAGLQVPKTVVSSWNRKAAEYGKKAKSETFRLLHAKNI 180
Query: 181 IRPQLKFREKIDNSNTPFLPKIFIKPNAQKPLPQALSKERRERPQDRPEDLDVPPALADF 240
IRPQLKFREKIDNSNTPFLPKIFIKPNAQKPLPQALSKERRERPQDRPEDLDVPPALADF
Sbjct: 181 IRPQLKFREKIDNSNTPFLPKIFIKPNAQKPLPQALSKERRERPQDRPEDLDVPPALADF 240
Query: 241 IHQQRTQQVEQDMFAHPYQYELNHFTPADAVLQKPQPQLYRPIEETPCHFISSLDELVEL 300
IHQQRTQQVEQDMFAHPYQYELNHFTPADAVLQKPQPQLYRPIEETPCHFISSLDELVEL
Sbjct: 241 IHQQRTQQVEQDMFAHPYQYELNHFTPADAVLQKPQPQLYRPIEETPCHFISSLDELVEL 300
Query: 301 NEKLLNCQEFAVDLEHHSYRSFLGLTCLMQISTRTEDFIIDTLELRSDMYILNESLTDPA 360
NEKLLNCQEFAVDLEHHSYRSFLGLTCLMQISTRTEDFIIDTLELRSDMYILNESLTDPA
Sbjct: 301 NEKLLNCQEFAVDLEHHSYRSFLGLTCLMQISTRTEDFIIDTLELRSDMYILNESLTDPA 360
Query: 361 IVKVFHGADSDIEWLQKDFGLYVVNMFDTHQAARLLNLGRHSLDHLLKLYCNVDSNKQYQ 420
IVKVFHGADSDIEWLQKDFGLYVVNMFDTHQAARLLNLGRHSLDHLLKLYCNVDSNKQYQ
Sbjct: 361 IVKVFHGADSDIEWLQKDFGLYVVNMFDTHQAARLLNLGRHSLDHLLKLYCNVDSNKQYQ 420
Query: 421 LADWRIRPLPEEMLSYARDDTHYLLYIYDKMRLEMWERGNGQPVQLQVVWQRSRDICLKK 480
LADWRIRPLPEEMLSYARDDTHYLLYIYDKMRLEMWERGNGQPVQLQVVWQRSRDICLKK
Sbjct: 421 LADWRIRPLPEEMLSYARDDTHYLLYIYDKMRLEMWERGNGQPVQLQVVWQRSRDICLKK 480
Query: 481 FIKPIFTDESYLELYRKQKKHLNTQQLTAFQLLFAWRDKTARREDESYGYVLPNHMMLKI 540
FIKPIFTDESYLELYRKQKKHLNTQQLTAFQLLFAWRDKTARREDESYGYVLPNHMMLKI
Sbjct: 481 FIKPIFTDESYLELYRKQKKHLNTQQLTAFQLLFAWRDKTARREDESYGYVLPNHMMLKI 540
Query: 541 AEELPKEPQGIIACCNPVPPLVRQQINEMHLLIQQAREMPLLKSEVAAGVKKSGPLPSAE 600
AEELPKEPQGIIACCNPVPPLVRQQINEMHLLIQQAREMPLLKSEVAAGVKKSGPLPSAE
Sbjct: 541 AEELPKEPQGIIACCNPVPPLVRQQINEMHLLIQQAREMPLLKSEVAAGVKKSGPLPSAE 600
Query: 601 RLENVLFGPHDCSHAPPDGYPIIPTSGSVPVQKQASLFPDEKEDNLLGTTCLIATAVITL 660
RLENVLFGPHDCSHAPPDGYPIIPTSGSVPVQKQASLFPDEKEDNLLGTTCLIATAVITL
Sbjct: 601 RLENVLFGPHDCSHAPPDGYPIIPTSGSVPVQKQASLFPDEKEDNLLGTTCLIATAVITL 660
Query: 661 FNEPSAEDSKKGPLTVAQKKAQNIMESFENPFRM-------------------------I 695
FNEPSAEDSKKGPLTVAQKKAQNIMESFENPFRM I
Sbjct: 661 FNEPSAEDSKKGPLTVAQKKAQNIMESFENPFRMFLPSLGHRAPVSQAAKFDPSTKIYEI 720
Query: 696 SNRWKLAQVQVQKDSKEAVKKKAAEQTAAREQAKEACKAAAEQAISVRQQVVLENAAKKR 755
SNRWKLAQVQVQKDSKEAVKKKAAEQTAAREQAKEACKAAAEQAISVRQQVVLENAAKKR
Sbjct: 721 SNRWKLAQVQVQKDSKEAVKKKAAEQTAAREQAKEACKAAAEQAISVRQQVVLENAAKKR 780
Query: 756 ERATSDPRTTEQKQEKKRLKISKKPKDPEPPEKEFTPYDYSQSDFKAFAGNSKSKVSSQF 815
ERATSDPRTTEQKQEKKRLKISKKPKDPEPPEKEFTPYDYSQSDFKAFAGNSKSKVSSQF
Sbjct: 781 ERATSDPRTTEQKQEKKRLKISKKPKDPEPPEKEFTPYDYSQSDFKAFAGNSKSKVSSQF 840
Query: 816 DPNKQTPSGKKCIAAKKIKQSVGNKSMSFPTGKSDRGFRYNWPQR 860
DPNKQTPSGKKCIAAKKIKQSVGNKSMSFPTGKSDRGFRYNWPQR
Sbjct: 841 DPNKQTPSGKKCIAAKKIKQSVGNKSMSFPTGKSDRGFRYNWPQR 885
>gi|104526627 triadin [Homo sapiens]
Length = 729
Score = 45.8 bits (107), Expect = 2e-04
Identities = 38/138 (27%), Positives = 66/138 (47%), Gaps = 10/138 (7%)
Query: 705 QVQKDSKEAVKKKAAEQTAAREQAKEACKAAAEQAISVRQQVVLENAAKKRE-----RAT 759
+ +K KE +KKK+ ++TA + KE KA+ + +V+ + + AAKK E + T
Sbjct: 326 ETKKKEKEDIKKKSEKETAIDVEKKEPGKASETKQGTVK--IAAQAAAKKDEKKEDSKKT 383
Query: 760 SDPRTTEQKQEKKRLKISKKPKDPEPPEKEFTPYDYSQSDFKAFAGNSKSKVSSQFDPNK 819
P EQ + KK+ K K + + P+KE + S KA +K ++ + K
Sbjct: 384 KKPAEVEQPKGKKQEKKEKHVEPAKSPKKEHSV--PSDKQVKAKTERAKEEIGA-VSIKK 440
Query: 820 QTPSGKKCIAAKKIKQSV 837
P K+ K ++Q +
Sbjct: 441 AVPGKKEEKTTKTVEQEI 458
Score = 33.5 bits (75), Expect = 0.87
Identities = 41/159 (25%), Positives = 69/159 (43%), Gaps = 27/159 (16%)
Query: 667 EDSKKGPLTVAQKKAQNI----MESFENPFRMISNRWKLAQVQVQKDSKEAVKKKAAEQT 722
ED+ KG + + + I E E P R I Q +V KE K+K
Sbjct: 126 EDTDKGEIDEPPLRKKEIHKDKTEKQEKPERKI-------QTKVTHKEKEKGKEKV---- 174
Query: 723 AAREQAKEACKAAAEQAISVRQQVVLENAAKKRERATSDPRTTEQKQE--KKRLKISKKP 780
RE+ K KA ++ I +++ + AK++++A +T E+ +E KK +K K+
Sbjct: 175 --REKEKPEKKATHKEKIEKKEKPETKTLAKEQKKA----KTAEKSEEKTKKEVKGGKQE 228
Query: 781 KDPEPPEK----EFTPYDYSQSDFKAFAGNSKSKVSSQF 815
K + K + TP + + K A SK + Q+
Sbjct: 229 KVKQTAAKVKEVQKTPSKPKEKEDKEKAAVSKHEQKDQY 267
>gi|145279204 exonuclease 3'-5' domain containing 3 [Homo sapiens]
Length = 876
Score = 44.3 bits (103), Expect = 5e-04
Identities = 47/201 (23%), Positives = 88/201 (43%), Gaps = 32/201 (15%)
Query: 282 PIEETPCHFISSLDELVELNEKLLNC-QEFAVDLEHHSYRSFLGLT--CLMQISTRTEDF 338
PI H ++S ++L LL C Q VD+E G L+Q++ F
Sbjct: 367 PIPRENVHLLASWEDLTRHEGALLQCHQVVGVDVEWTPVFVAGGRPRPSLLQVAVEGHVF 426
Query: 339 IIDTLEL---------RSDMYILNESLTDPAIVKVFHGADSDIEWL----------QKDF 379
++D L L ++ ++ + L+DP+I K+ +G D++ L +K
Sbjct: 427 LLDVLALSQPPTGQGAQAFSRLVAQLLSDPSITKLGYGMVGDLQKLGTSCPALAHVEKQI 486
Query: 380 GLYVVNMFDTHQAARLLNLGRHSLDH---------LLKLYCNVDSNKQYQLADWRIRPLP 430
L +++ H+ R+ ++ ++D L++ +K QL++W RPL
Sbjct: 487 -LGGMDLLLVHRQMRVASVPAPAVDRARELRGLSLLVQQVLGTALDKTQQLSNWDRRPLC 545
Query: 431 EEMLSYARDDTHYLLYIYDKM 451
EE + YA D + LL ++ +
Sbjct: 546 EEQVIYAAADAYCLLEVHQAL 566
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 42.0 bits (97), Expect = 0.002
Identities = 36/138 (26%), Positives = 65/138 (47%), Gaps = 18/138 (13%)
Query: 663 EPSAEDSKKGPLTVAQKKAQNIMESFENPFRMISNRWKLAQVQVQKDSKEAVKKKAAEQT 722
EP+ E K+ + +++A++ + P + A+V+V++D+K K + A++
Sbjct: 879 EPAVEKPKESKVEAKKEEAED-KKKVPTPEKEAP-----AKVEVKEDAKPKEKTEVAKKE 932
Query: 723 AAREQAKEACKAAAEQAISVRQQVVLENAAKKRE-------RATSDPRT-----TEQKQE 770
+AKE K A ++ + ++ E AKK E +A D +T ++ K E
Sbjct: 933 PDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAE 992
Query: 771 KKRLKISKKPKDPEPPEK 788
K S KD +PPEK
Sbjct: 993 KAEKSSSTDQKDSKPPEK 1010
Score = 38.5 bits (88), Expect = 0.027
Identities = 34/144 (23%), Positives = 59/144 (40%), Gaps = 5/144 (3%)
Query: 702 AQVQVQKDSKEAVKKKAAEQTAAREQAKEACKAAAEQAISVRQQVVLENAAKKRERATSD 761
A+ + + +K VK++A A+ KE K+ AE + + + AK E+A S
Sbjct: 596 AEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSP 655
Query: 762 PRTTEQKQEKKRLKISKKPKDPE----PPEKEFTPYDYSQSDFKAFAGNSKSKVSSQFDP 817
+ + EK + + + K PE P + E + ++S K A S K S
Sbjct: 656 EKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEA-KSPEKAKSPVKE 714
Query: 818 NKQTPSGKKCIAAKKIKQSVGNKS 841
++P K ++ K KS
Sbjct: 715 EAKSPEKAKSPVKEEAKTPEKAKS 738
Score = 37.0 bits (84), Expect = 0.078
Identities = 40/191 (20%), Positives = 79/191 (41%), Gaps = 5/191 (2%)
Query: 664 PSAEDSKKGPLTVAQKKAQ-NIMESFENPFRMISNRWKLAQVQVQKDSK--EAVKKKAAE 720
P+ E++K + +K + E ++P + + + A+ V+ ++K E K E
Sbjct: 641 PTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKE 700
Query: 721 QTAAREQAKEACKAAAEQAISVRQQVVLENAAKKRERATSDPRTTEQKQEKKRLKISKKP 780
+ + E+AK K A+ + V E AK E+A S + + EK + K
Sbjct: 701 EAKSPEKAKSPVKEEAKSPEKAKSPVKEE--AKTPEKAKSPVKEEAKSPEKAKSPEKAKT 758
Query: 781 KDPEPPEKEFTPYDYSQSDFKAFAGNSKSKVSSQFDPNKQTPSGKKCIAAKKIKQSVGNK 840
D + PE + + ++S F +KS V + ++ S K A K+ +
Sbjct: 759 LDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKE 818
Query: 841 SMSFPTGKSDR 851
+ P + ++
Sbjct: 819 EVKSPVKEEEK 829
Score = 35.4 bits (80), Expect = 0.23
Identities = 43/164 (26%), Positives = 64/164 (39%), Gaps = 20/164 (12%)
Query: 704 VQVQKDSKEAVKKKAAEQTAAREQA---KEACKAAAEQAISVRQQVVLENAAK-KRERAT 759
V+ + S E K E A E+ KE K+ ++ ++ V E K + E+A
Sbjct: 789 VKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAP 848
Query: 760 SDPRTTEQKQEKKR---LKISKKPKDPEPPEKEFTPYDYSQSDFKAFAGNSKSKVSSQFD 816
+ P+T E+K KK K + KPK E E S+ + K K KV +
Sbjct: 849 ATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPT--- 905
Query: 817 PNKQTPS----------GKKCIAAKKIKQSVGNKSMSFPTGKSD 850
P K+ P+ +K AKK K S P K +
Sbjct: 906 PEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKE 949
Score = 35.0 bits (79), Expect = 0.30
Identities = 42/206 (20%), Positives = 74/206 (35%), Gaps = 28/206 (13%)
Query: 663 EPSAEDSKKGPLTVAQKKAQN----IMESFENPFRMISNRWKLAQVQVQKDSKEAVKKKA 718
E + + K P+ K + E ++P + S + + + S E K
Sbjct: 597 EAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPE 656
Query: 719 AEQTAAREQAKEACKAAAEQAISVRQQVVLE------------NAAKKRERATSDPRTTE 766
E+ + E+AK KA A+ + V E AK E+A S +
Sbjct: 657 KEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEA 716
Query: 767 QKQEKKRLKISKKPKDPE-----------PPEKEFTPYDYSQSDFKAFAGNSKSKVSSQF 815
+ EK + + ++ K PE PEK +P D K+ + +K ++
Sbjct: 717 KSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEAR- 775
Query: 816 DPNKQTPSGKKCIAAKKIKQSVGNKS 841
P + P K +++K KS
Sbjct: 776 SPADKFPEKAKSPVKEEVKSPEKAKS 801
Score = 34.7 bits (78), Expect = 0.39
Identities = 35/151 (23%), Positives = 64/151 (42%), Gaps = 10/151 (6%)
Query: 706 VQKDSKEAV-KKKAAEQTAAREQAKEACKAAAEQAISVRQQVVLENAAKKRERATSDPRT 764
V+K KE V ++ E+T E+ E + A++ ++ E A+ E T P
Sbjct: 447 VEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPA 506
Query: 765 TEQKQEKKRLKI-----SKKPKDPEPPEKEFTPYDYSQSDFKA-FAGNSKSKVSSQFDPN 818
E +K K +K P + + PEKE S ++ K+ S +K ++ P
Sbjct: 507 EEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAK---SPAEVKSPEKAKSPAKEEAKSPPE 563
Query: 819 KQTPSGKKCIAAKKIKQSVGNKSMSFPTGKS 849
++P ++ + ++K KS + KS
Sbjct: 564 AKSPEKEEAKSPAEVKSPEKAKSPAKEEAKS 594
Score = 30.0 bits (66), Expect = 9.6
Identities = 48/222 (21%), Positives = 85/222 (38%), Gaps = 37/222 (16%)
Query: 663 EPSAEDSKKGPLTVAQKKAQNIMESFENPFRMISNRWKLAQVQVQKDSKEAVKKKAA--- 719
E + + K PL K + + E + K +V+V++ K+A ++KA
Sbjct: 792 EVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATP 851
Query: 720 ----------EQTAAREQAKEACKAAAEQAISVRQQVVLENAAKKRE------------R 757
E+ +E K + E A+ ++ +E AKK E
Sbjct: 852 KTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVE--AKKEEAEDKKKVPTPEKE 909
Query: 758 ATSDPRTTEQKQEKKRLKISK------KPKDPEPP--EKEFTPYDYSQSDFKAFAGNSKS 809
A + E + K++ +++K K K+P P +KE P + KA K
Sbjct: 910 APAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKP 969
Query: 810 KVSSQFDPNKQTPSGK--KCIAAKKIKQSVGNKSMSFPTGKS 849
K ++ + +T S + K A K K S ++ S P K+
Sbjct: 970 KTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKA 1011
>gi|56961680 coiled-coil domain containing 147 [Homo sapiens]
Length = 872
Score = 40.4 bits (93), Expect = 0.007
Identities = 34/153 (22%), Positives = 69/153 (45%), Gaps = 4/153 (2%)
Query: 662 NEPSAEDSKKGPLTVAQKKAQNIMESFENPFRMISNRWKLAQVQVQKDSKEAVKKKAAEQ 721
NE S E KK L K+ Q M+S + + + + ++ ++QK ++ ++K +
Sbjct: 209 NEASREFRKKEKLEKELKQIQADMDSRQTEIKALQQYVQKSKEELQKLEQQLKEQKILNE 268
Query: 722 TAAREQAKEACKAAAEQAISVRQQVVLENAAKKRERATSDPRTTEQKQEKKRLKISKKPK 781
AA+E + + A Q + + +V E +++ ++ + + E++ + RL I K K
Sbjct: 269 RAAKELEQFQMRNAKLQQENEQHSLVCEQLSQENQQKALELKAKEEEVHQMRLDIGKLNK 328
Query: 782 DPEPPEKEFTPYDYSQSDFKAFAGNSKSKVSSQ 814
E K+ + D KA K + +Q
Sbjct: 329 IREQIHKKL----HHTEDQKAEVEQHKETLKNQ 357
>gi|38788260 bromodomain PHD finger transcription factor isoform 2
[Homo sapiens]
Length = 2903
Score = 39.7 bits (91), Expect = 0.012
Identities = 30/106 (28%), Positives = 54/106 (50%), Gaps = 3/106 (2%)
Query: 678 QKKAQNIMESFENPFRMISNR-WKLAQVQVQKDSKEAVKKKAAEQTAAREQAKEACKAAA 736
QKK+ E EN ++ N+ K ++ K+ K+A KK+ E++ ++++K+ +
Sbjct: 2536 QKKSMTPAEREENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQKRSKQNATKLS 2595
Query: 737 EQAISVRQQVVLENAAKKRERATSDPRTTEQKQEKKRLKISKKPKD 782
++Q+ E KKR D + Q++ K+ LKI KK KD
Sbjct: 2596 ALLFKHKEQLRAE-ILKKRALLDKDLQIEVQEELKRDLKI-KKEKD 2639
>gi|38788274 bromodomain PHD finger transcription factor isoform 1
[Homo sapiens]
Length = 2920
Score = 39.7 bits (91), Expect = 0.012
Identities = 30/106 (28%), Positives = 54/106 (50%), Gaps = 3/106 (2%)
Query: 678 QKKAQNIMESFENPFRMISNR-WKLAQVQVQKDSKEAVKKKAAEQTAAREQAKEACKAAA 736
QKK+ E EN ++ N+ K ++ K+ K+A KK+ E++ ++++K+ +
Sbjct: 2553 QKKSMTPAEREENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQKRSKQNATKLS 2612
Query: 737 EQAISVRQQVVLENAAKKRERATSDPRTTEQKQEKKRLKISKKPKD 782
++Q+ E KKR D + Q++ K+ LKI KK KD
Sbjct: 2613 ALLFKHKEQLRAE-ILKKRALLDKDLQIEVQEELKRDLKI-KKEKD 2656
>gi|239748665 PREDICTED: hypothetical protein [Homo sapiens]
Length = 223
Score = 38.9 bits (89), Expect = 0.021
Identities = 31/107 (28%), Positives = 49/107 (45%), Gaps = 19/107 (17%)
Query: 267 PADAVLQKP-QPQLYRPIEETPCHFISS-----------------LDELVELNEKLLNCQ 308
PA L P Q L+ P ETP F++S L L+ + +L Q
Sbjct: 70 PAQGSLLSPAQVGLFLPRRETPIPFVTSNKDIPAASPSCATSCYLLPSLLPHSSAILRNQ 129
Query: 309 EFAVDLEHHSYRSFLGLTCLMQISTRTEDFIIDTLELRSDMYILNES 355
++DL S+RS LGL CL+++ T ++ TL R + I+ ++
Sbjct: 130 TASMDLGRQSWRSSLGLLCLVELITAVA-CLLKTLRSRGQLTIVEQN 175
>gi|239742690 PREDICTED: hypothetical protein [Homo sapiens]
Length = 223
Score = 38.9 bits (89), Expect = 0.021
Identities = 31/107 (28%), Positives = 49/107 (45%), Gaps = 19/107 (17%)
Query: 267 PADAVLQKP-QPQLYRPIEETPCHFISS-----------------LDELVELNEKLLNCQ 308
PA L P Q L+ P ETP F++S L L+ + +L Q
Sbjct: 70 PAQGSLLSPAQVGLFLPRRETPIPFVTSNKDIPAASPSCATSCYLLPSLLPHSSAILRNQ 129
Query: 309 EFAVDLEHHSYRSFLGLTCLMQISTRTEDFIIDTLELRSDMYILNES 355
++DL S+RS LGL CL+++ T ++ TL R + I+ ++
Sbjct: 130 TASMDLGRQSWRSSLGLLCLVELITAVA-CLLKTLRSRGQLTIVEQN 175
>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
Length = 953
Score = 38.9 bits (89), Expect = 0.021
Identities = 35/168 (20%), Positives = 69/168 (41%), Gaps = 22/168 (13%)
Query: 697 NRWKLAQVQVQKDSKEAVKKKAAEQTAAREQAKEACKAAAEQAISVRQQVVLENAAKKRE 756
NR + + + ++D + +++ E+ E+ KE + E E KR+
Sbjct: 412 NRQRERERERERDRERERRQREREREREHERDKERQRRKEEW----------ERERAKRD 461
Query: 757 RATSDPRTTEQKQEKKRLKISKKPKDPEPPEKEFTPYDYSQSDFKAFAGNSKSKVSSQFD 816
R ++++E+++ K KP+ P+PP ++ P A G + D
Sbjct: 462 EKDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEP----PKKEAATTGPQVKRADEWKD 517
Query: 817 PNKQTPSGKKCI--------AAKKIKQSVGNKSMSFPTGKSDRGFRYN 856
P +++ S KK + A ++ K S + S S + S R Y+
Sbjct: 518 PWRRSKSPKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYS 565
>gi|87116683 proline/serine-rich coiled-coil 2 [Homo sapiens]
Length = 1989
Score = 38.5 bits (88), Expect = 0.027
Identities = 27/131 (20%), Positives = 60/131 (45%), Gaps = 15/131 (11%)
Query: 696 SNRWKLAQVQVQKDSKEAVKKKAAEQ----TAAREQAKEACKAAAEQAISVRQ----QVV 747
S +W+ + QV K+SKE + K Q T+ + + + A+QA+ +Q + +
Sbjct: 383 SKKWQQKEQQVMKESKEKLTKTKTVQQKVKTSTKTHSAKKVSTTAKQALRKQQTKAWKKL 442
Query: 748 LENAAKKRERATSDPRTTEQKQEKKRLKISKKPKDPEPPEKEFTPYDYSQSDFKAFAGNS 807
+ ++R++ + E+++ +KR + +K +D E+++ + F G
Sbjct: 443 QQQKEQERQKEEDQRKQAEEEERRKREEEIRKIRDLSNQEEQY-------NRFMKLVGGK 495
Query: 808 KSKVSSQFDPN 818
+ S DP+
Sbjct: 496 RRSRSKSSDPD 506
>gi|189409142 telomeric repeat binding factor 1 isoform 1 [Homo
sapiens]
Length = 439
Score = 38.1 bits (87), Expect = 0.035
Identities = 50/232 (21%), Positives = 96/232 (41%), Gaps = 23/232 (9%)
Query: 562 VRQQINEMHLLIQQAREMPLLKSEVAAGVKKSGPLPSAERLENVLFGPHDCSHAPPDGYP 621
+ ++ +++H IQ L+K + A ++G AE + +FG + SH P
Sbjct: 161 IEKEHDKLHEEIQN-----LIKIQAIAVCMENGNFKEAEEVFERIFGDPN-SHMPFKSKL 214
Query: 622 IIPTSGSVPVQKQA--SLFPDEKEDNLLGTTCLIATAVITLFNEPSAEDSKKGPLTVAQK 679
++ S QK S F ++++ I + V + +E S+ K V +
Sbjct: 215 LMIIS-----QKDTFHSFFQHFSYNHMMEK---IKSYVNYVLSEKSSTFLMKAAAKVVES 266
Query: 680 KAQNIMESFENPFRMISNRWKLAQVQVQKDSKEAVKKKAAEQTAAREQAKEACKAAAEQA 739
K + S + P S + + D++++V K + T + E ++
Sbjct: 267 KRTRTITSQDKP----SGNDVEMETEANLDTRKSVSDKQSAVTESSEGTVSLLRSHKNLF 322
Query: 740 ISVRQQVVLENAAKKRERATSDPRTTEQKQEKKRLKISKKP---KDPEPPEK 788
+S Q + K+ER P++T++K+E +R S+ P P PEK
Sbjct: 323 LSKLQHGTQQQDLNKKERRVGTPQSTKKKKESRRATESRIPVSKSQPVTPEK 374
>gi|95147555 microtubule-associated protein 1A [Homo sapiens]
Length = 2803
Score = 38.1 bits (87), Expect = 0.035
Identities = 36/171 (21%), Positives = 75/171 (43%), Gaps = 6/171 (3%)
Query: 626 SGSVPVQKQASLFP---DEKEDNLLGTTCLIATAVITLFNEPSAEDSKKGPLTVAQKKAQ 682
SG+VP + S D KE L T A + + E E +K+ +A++ A+
Sbjct: 301 SGAVPTNLKPSKIKQRADSKES--LKATTKTAVSKLAKREEVVEEGAKEARSELAKELAK 358
Query: 683 NIMESFENPFRMISNRWKLAQVQVQK-DSKEAVKKKAAEQTAAREQAKEACKAAAEQAIS 741
++ E+ + K +V+ + ++ +A K+K + ++ KE E+
Sbjct: 359 TEKKAKESSEKPPEKPAKPERVKTESSEALKAEKRKLIKDKVGKKHLKEKISKLEEKKDK 418
Query: 742 VRQQVVLENAAKKRERATSDPRTTEQKQEKKRLKISKKPKDPEPPEKEFTP 792
++++ E K++ + + +K+EK++ + K +P K FTP
Sbjct: 419 EKKEIKKERKELKKDEGRKEEKKDAKKEEKRKDTKPELKKISKPDLKPFTP 469
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 37.7 bits (86), Expect = 0.046
Identities = 27/122 (22%), Positives = 55/122 (45%), Gaps = 1/122 (0%)
Query: 711 KEAVKKKAAEQTAAREQAKEACKAAAEQAISVRQQVVLENAAKKRERATSDPRTTEQKQE 770
K+ KKK E+T E+ +E + ++ R++ E KK+ + T + E++++
Sbjct: 2 KKKKKKKETEETEETEETEEEEEKEGKRK-EKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60
Query: 771 KKRLKISKKPKDPEPPEKEFTPYDYSQSDFKAFAGNSKSKVSSQFDPNKQTPSGKKCIAA 830
K++ K KK ++ E E+E + + + K K K + ++ K+
Sbjct: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120
Query: 831 KK 832
KK
Sbjct: 121 KK 122
Score = 30.8 bits (68), Expect = 5.6
Identities = 25/112 (22%), Positives = 47/112 (41%), Gaps = 5/112 (4%)
Query: 678 QKKAQNIMESFENPFRMISNRWKLAQVQVQKDSKEAVKKKAAEQTAAREQAKEACKAAAE 737
+KK E E K + + +K ++ KKK E +E+ +E K +
Sbjct: 6 KKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRK 65
Query: 738 QAISVRQQVVLENAAKKRERATSDPRTTEQKQEKKRLKISKKPKDPEPPEKE 789
R++ E ++ E + + E+K+E +R K KK + E E++
Sbjct: 66 -----RKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEK 112
Score = 30.4 bits (67), Expect = 7.3
Identities = 28/117 (23%), Positives = 52/117 (44%), Gaps = 11/117 (9%)
Query: 663 EPSAEDSKKGPLTVAQKKAQNIMESFENPFRMISNRWKLAQVQVQKDSKEAVKKKAAEQT 722
E E+ K+G +K+ + E + + + K + + +K ++ KKK E+
Sbjct: 18 ETEEEEEKEGKRK--EKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEER 75
Query: 723 AAREQAKEACKAAAEQAISVRQQVVLENAAKKRERATSDPRTTEQKQEKKRLKISKK 779
E+ +E K E+ R++ KKR R + E+K++K+R K KK
Sbjct: 76 EEEEEEEEEEKEEEEKEEGRRRK-----KKKKRRRKEEE----EEKKKKRRRKTKKK 123
>gi|4506467 radixin [Homo sapiens]
Length = 583
Score = 37.7 bits (86), Expect = 0.046
Identities = 30/115 (26%), Positives = 53/115 (46%), Gaps = 13/115 (11%)
Query: 705 QVQKDSKEAVKKKAAEQTAAREQAKEACKAAAEQAISVRQQVVLENAAKKRE-------- 756
+++K+ + A + K+A A +Q K + AAE A + +LE A KK+E
Sbjct: 388 RLEKERRAAEEAKSAIAKQAADQMKNQEQLAAELAEFTAKIALLEEAKKKKEEEATEWQH 447
Query: 757 RATSDPRTTEQKQEKKRLKISKKPKDPEPP-----EKEFTPYDYSQSDFKAFAGN 806
+A + E+ +E+ + +S P P PP E E +D + ++ A N
Sbjct: 448 KAFAAQEDLEKTKEELKTVMSAPPPPPPPPVIPPTENEHDEHDENNAEASAELSN 502
>gi|54112403 chromodomain helicase DNA binding protein 7 [Homo
sapiens]
Length = 2997
Score = 37.7 bits (86), Expect = 0.046
Identities = 26/89 (29%), Positives = 42/89 (47%), Gaps = 7/89 (7%)
Query: 749 ENAAKKRERATSDPRTTEQKQEKKRLKISKKPKDPEPPEKEFTPYDYSQSDFKAFAGNSK 808
E KKR +A DP+ ++ +EK K+PK+P+ P+ P + + K K
Sbjct: 640 EKKKKKRSKAKKDPKEPKEPKEK------KEPKEPKTPKAPKIPKEPKEKKAKTATPKPK 693
Query: 809 -SKVSSQFDPNKQTPSGKKCIAAKKIKQS 836
SK SS P+ + + KK + K + S
Sbjct: 694 SSKKSSNKKPDSEASALKKKVNKGKTEGS 722
Score = 33.1 bits (74), Expect = 1.1
Identities = 24/89 (26%), Positives = 42/89 (47%), Gaps = 5/89 (5%)
Query: 766 EQKQEKKRLKISKKPKDPEPPEKEFTPYDYSQSDFKAFAGNSKSKVSSQFDP----NKQT 821
E+K++KKR K K PK+P+ P+++ P + K K + P +K++
Sbjct: 639 EEKKKKKRSKAKKDPKEPKEPKEKKEPKEPKTPKAPKIPKEPKEKKAKTATPKPKSSKKS 698
Query: 822 PSGKKCIAAKKIKQSVGNKSMSFPTGKSD 850
+ K A +K+ V NK + + SD
Sbjct: 699 SNKKPDSEASALKKKV-NKGKTEGSENSD 726
>gi|68508961 centromere protein C 1 [Homo sapiens]
Length = 943
Score = 37.7 bits (86), Expect = 0.046
Identities = 34/156 (21%), Positives = 70/156 (44%), Gaps = 7/156 (4%)
Query: 659 TLFNEPSAEDSKKGPLTVAQKKAQNIMESFENPFRMISNRWKLAQVQVQKDSKEAVKKKA 718
TL N+ + K P+ +Q + ++++ N ++ + ++ SK A K
Sbjct: 357 TLANDKHSH--KPHPVETSQPSDKTVLDTSYALIGETVNNYRSTKYEMY--SKNAEKPSR 412
Query: 719 AEQTAAREQAKEACKAAAEQAISVRQ---QVVLENAAKKRERATSDPRTTEQKQEKKRLK 775
+++T ++Q ++ AE+ + V Q + + + + E + R E+ +E
Sbjct: 413 SKRTIKQKQRRKFMAKPAEEQLDVGQSKDENIHTSHITQDEFQRNSDRNMEEHEEMGNDC 472
Query: 776 ISKKPKDPEPPEKEFTPYDYSQSDFKAFAGNSKSKV 811
+SKK P +K T D +S K F+ SK+K+
Sbjct: 473 VSKKQMPPVGSKKSSTRKDKEESKKKRFSSESKNKL 508
>gi|154354979 myosin X [Homo sapiens]
Length = 2058
Score = 37.7 bits (86), Expect = 0.046
Identities = 34/143 (23%), Positives = 65/143 (45%), Gaps = 9/143 (6%)
Query: 698 RWKLAQVQVQKDSK---EAVKKKAAEQTAAREQAKEACKAAAEQAISVRQQVVLENAAKK 754
R LA+ + Q++ K E KKK E+ RE+ + + A+Q R+Q LE K
Sbjct: 809 RQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEETRKQQELEALQKS 868
Query: 755 RERATSDPRTTEQKQEKKRLKISKKPKDPEPPEKEFTPYDYSQSDFKAFAGNSKSKVSSQ 814
++ A +QK+ K+ +I + K+ E ++ + S ++ S K+ +
Sbjct: 869 QKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTE------ASLQKLQER 922
Query: 815 FDPNKQTPSGKKCIAAKKIKQSV 837
D + + C AA++ +S+
Sbjct: 923 RDQELRRLEEEACRAAQEFLESL 945
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 37.7 bits (86), Expect = 0.046
Identities = 37/174 (21%), Positives = 74/174 (42%), Gaps = 5/174 (2%)
Query: 664 PSAEDSKKGPLTVAQKKAQNIMESFENPFRMISNRWKLAQVQVQKDSKEAVKKKAAEQTA 723
PS E+ VA+K+A ++ + + K+ + + +K+ KE KK+ A++
Sbjct: 608 PSKEEPSPVKAEVAEKQATDVKPKAAKE-KTVKKETKV-KPEDKKEEKEKPKKEVAKKED 665
Query: 724 AREQAKEACKAAAEQAISVRQQVVLENAAKKRERATSDPRTTEQKQEKKRLKISKKPKDP 783
KE E V++++ E + ++ + E K+E K+ + + K+
Sbjct: 666 KTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEE 725
Query: 784 EPPEKEF--TPYDYSQSDFKAFAGNSKSKVSSQFDPNKQTPSGKKCIAAKKIKQ 835
+ P+KE P D +S + + + P K+ K +AA K K+
Sbjct: 726 KEPKKEIKKLPKDAKKSSTPLSEAKKPAALKPKV-PKKEESVKKDSVAAGKPKE 778
>gi|90093355 jumonji C domain containing histone demethylase 1
homolog D [Homo sapiens]
Length = 941
Score = 37.4 bits (85), Expect = 0.060
Identities = 56/251 (22%), Positives = 101/251 (40%), Gaps = 28/251 (11%)
Query: 610 HDCSHAPPDGYPIIPTSGSVPVQKQASLFPDEKEDNLLGTTCLIATAVITLFNEPSAEDS 669
H+ S P +G+ T ++ ++S + D E G C ++ T S+ D
Sbjct: 631 HEESQKPLNGFF---TRVKSELRSRSSGYSDISESEDSGPECTALKSIFTTEESESSGDE 687
Query: 670 KKGPLTVAQKKAQNIMESFENPFRMISNRWKLAQVQVQKDSKEAVKKKAAEQTAAREQAK 729
KK +T K+ N+M +F L + Q S+ +K++ T+ E+A
Sbjct: 688 KKQEITSNFKEESNVMRNF------------LQKSQKPSRSEIPIKRECPTSTSTEEEAI 735
Query: 730 EACKAAAEQAISVRQQVVLENAAKKRER-ATSDPRTTE-QKQEKKRLKISKKPKDPEPPE 787
+ + A S Q +++ ER + DP + E ++L KP +
Sbjct: 736 QGMLSMAGLHYSTCLQRQIQSTDCSGERNSLQDPSSCHGSNHEVRQLYRYDKPVECGYHV 795
Query: 788 KEFTPYDYSQSDFKAFAGNSKSKVSSQFDPNKQTPSGKKCI---AAKKIKQSVGNKSMSF 844
K P + S K F +S+F P + S +KCI + +I Q V +++
Sbjct: 796 KTEDPDLRTSSWIKQFD-------TSRFHPQDLSRS-QKCIRKEGSSEISQRVQSRNYVD 847
Query: 845 PTGKSDRGFRY 855
+G S + +Y
Sbjct: 848 SSGSSLQNGKY 858
>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
[Homo sapiens]
Length = 651
Score = 37.4 bits (85), Expect = 0.060
Identities = 26/112 (23%), Positives = 49/112 (43%), Gaps = 2/112 (1%)
Query: 711 KEAVKKKAAEQTAAREQAKEACKAAAEQAISVRQQVVLENAAKKRERATSDPRTTEQKQE 770
K+A KK+ ++ K++ K A + + ++E K++ A P + + E
Sbjct: 111 KKAEYKKSKDEKGGTPLKKDSKKKGGSYATNPESKQIVEEKTKRQNEADKTPLKSSHENE 170
Query: 771 KKRLKISKKPKDPEPPEKEFTPYDYSQSDFKAFAGNSKSKVSSQFDPNKQTP 822
+ + S +PE + + SQ D K + NSK K +++F K P
Sbjct: 171 QSKKSKSSSETNPESQNSKTVSKNCSQKD-KKDSKNSK-KTNTEFLHTKNNP 220
Score = 32.0 bits (71), Expect = 2.5
Identities = 35/139 (25%), Positives = 61/139 (43%), Gaps = 16/139 (11%)
Query: 707 QKDSKEAVKKKAAEQTAAREQAKEACKAAAEQAIS--VRQQVVLENAAKKRERATSDPRT 764
+KD+K+ KK + ++ + AK+ K + ++ V + + E S
Sbjct: 285 KKDTKKNAKKSSDAESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDER 344
Query: 765 TEQKQEKKRLKISKKPKDPEP-PEKEFTPYDYSQSDFKAFAGNSKS-KVSSQFDPNKQTP 822
+ K++KK+LK K KD + PE D D K +S++ K +S+ D K+
Sbjct: 345 KDTKKDKKKLKKDDKKKDTKKYPEST----DTESGDAKDARNDSRNLKKASKNDDKKKD- 399
Query: 823 SGKKCIAAKKIKQSVGNKS 841
AKKI S ++S
Sbjct: 400 -------AKKITFSTDSES 411
Score = 31.6 bits (70), Expect = 3.3
Identities = 48/197 (24%), Positives = 76/197 (38%), Gaps = 38/197 (19%)
Query: 662 NEPSAEDSKKGPLTVAQKKAQNIMESFE--NPFRMISNRWKLAQVQVQKDSKEAVKKKAA 719
++ + KK T +K +N ES + + + S + K + + +KDSK+ KKK A
Sbjct: 418 SQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDA 477
Query: 720 EQTAAREQAKEACKAAAEQAISVRQQVVLENAAKKRERATSDPRTTEQKQEKKRLKISKK 779
++ A + + SD + K+ K K SKK
Sbjct: 478 KKNAESTEME------------------------------SDLELKKDKKHSKEKKGSKK 507
Query: 780 P-KDPEPPEKEFTPYDYSQSDFKAFAGNSKSKVSSQFDPNKQTPSGKKCIAAKKIKQSVG 838
K + E T ++ +S F ++K K S G K KKI +S G
Sbjct: 508 DIKKDARKDTESTDAEFDESSKTGFKTSTKIKGSDTESEESLYKPGAK----KKIDESDG 563
Query: 839 NKSMSFPTG-KSDRGFR 854
+ S G +S RGFR
Sbjct: 564 TSANSKMEGLESKRGFR 580
>gi|187761317 tet oncogene family member 2 isoform a [Homo sapiens]
Length = 2002
Score = 36.6 bits (83), Expect = 0.10
Identities = 26/97 (26%), Positives = 45/97 (46%), Gaps = 17/97 (17%)
Query: 704 VQVQKDSKEAVKKKAAEQTAAREQAKEACKAAAEQAISVRQQVVLENAAKKRERATSDPR 763
+QV + V+ A R++ EA KAAAE+ S LEN++ K E+ S P
Sbjct: 1444 IQVLSSFRRKVRMLAEPVKTCRQRKLEAKKAAAEKLSS------LENSSNKNEKEKSAPS 1497
Query: 764 TTEQKQEKKRLK-----------ISKKPKDPEPPEKE 789
T+Q + + K + ++ + P+P +K+
Sbjct: 1498 RTKQTENASQAKQLAELLRLSGPVMQQSQQPQPLQKQ 1534
>gi|11067749 bromodomain containing protein 3 [Homo sapiens]
Length = 726
Score = 36.6 bits (83), Expect = 0.10
Identities = 36/137 (26%), Positives = 61/137 (44%), Gaps = 4/137 (2%)
Query: 662 NEPSAEDSKKGPLTVAQKKAQNIMESFENPFRMISNRWKLAQVQVQKDSKEAVKKKAAEQ 721
+E S+ DS G +++A + E E + L+Q V K K+ KK+ ++
Sbjct: 443 SEESSSDS--GSSDSEEERATRLAELQEQLKAVHEQLAALSQAPVNKPKKKKEKKEKEKK 500
Query: 722 TAAREQAKEACKAAAEQAISVRQQVVLENAAKKRERA-TSDPRTTEQKQEKKRLKISKKP 780
+E+ KE K AE+ + + A +K+ A ++ TT +Q KK K +
Sbjct: 501 KKDKEKEKEKHKVKAEEEKKAKVAPPAKQAQQKKAPAKKANSTTTAGRQLKKGGKQASAS 560
Query: 781 KDPEPPEKEFTPYDYSQ 797
D E E+E P Y +
Sbjct: 561 YDSE-EEEEGLPMSYDE 576
>gi|27734775 hypothetical protein LOC286499 [Homo sapiens]
Length = 248
Score = 36.6 bits (83), Expect = 0.10
Identities = 33/180 (18%), Positives = 77/180 (42%), Gaps = 9/180 (5%)
Query: 667 EDSKKGPLTVAQKKAQNIMESFENPFRMISNRWKLAQVQVQKDSKEAVKKKAAEQTAARE 726
E+ K G +A+ + + + E+++ +R KL K KKK +++
Sbjct: 49 ENKKTGSKALAEFE-EKMNENWKKELE--KSREKLLSGNESSSKKRERKKKRKKKSCRSS 105
Query: 727 QAKEACKAAAEQAISVRQQVVLENAAKKRERAT--SDPRTTEQKQEKKRLKISKKPKDPE 784
+ + +++ + S ++ KK++ + S +T + + + + + KK K +
Sbjct: 106 SSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKD 165
Query: 785 PPEKEFTPYDYSQSDFKAFAG----NSKSKVSSQFDPNKQTPSGKKCIAAKKIKQSVGNK 840
EKE S+ K++ +S+S S ++ + Q ++C ++ K+ V K
Sbjct: 166 ETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKK 225
Score = 34.3 bits (77), Expect = 0.51
Identities = 29/135 (21%), Positives = 62/135 (45%), Gaps = 10/135 (7%)
Query: 709 DSKEAVKKKAAEQTAAREQAKEACKAAAEQAISVRQQVVLENAAKKRERATSDPRTTEQK 768
DS++ KK+ + + ++ ++ +++ ++ S ++ V K+++ + D E +
Sbjct: 119 DSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESV------KKKKKSKD----ETE 168
Query: 769 QEKKRLKISKKPKDPEPPEKEFTPYDYSQSDFKAFAGNSKSKVSSQFDPNKQTPSGKKCI 828
+EK +SKK K P +K + S+SD++ K + + + K+ KK
Sbjct: 169 KEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKK 228
Query: 829 AAKKIKQSVGNKSMS 843
KK + KS S
Sbjct: 229 QHKKHSKKKKKKSGS 243
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 36.2 bits (82), Expect = 0.13
Identities = 27/87 (31%), Positives = 39/87 (44%), Gaps = 17/87 (19%)
Query: 711 KEAVKKKAAEQTAAREQA-----------KEACKAAAEQAISVRQQVVLENAAKKRERAT 759
K KKK E+ E+ K+ K E+ +++VVL++ +KR
Sbjct: 10901 KAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKR---- 10956
Query: 760 SDPRTTEQKQEKKRLKISKKPKDPEPP 786
P E K E K+L+ KKP PEPP
Sbjct: 10957 --PEEEEPKVEPKKLEKVKKPAVPEPP 10981
Score = 32.7 bits (73), Expect = 1.5
Identities = 49/194 (25%), Positives = 75/194 (38%), Gaps = 13/194 (6%)
Query: 664 PSAEDSKKGPLTVAQKKAQNIME--SFENPFRMISNRWKL-AQVQVQKDSKEAVKKKAAE 720
P AE SKK TV ++K E SF P R+ R ++ A+ + +E +
Sbjct: 9453 PRAEVSKK---TVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEWSYSEEEEGVSISVY 9509
Query: 721 QTAAREQAKEACKAAAEQAISVRQQVVLENAAKKRERATSDPRTTEQKQEKK---RLKIS 777
+ RE+ +EA E + VV E +R ++P ++QEKK + KI
Sbjct: 9510 REEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPAEVTERQEKKIVLKPKIP 9569
Query: 778 KKPKDPEPPEKEFTPYDYSQSDFKAFAGNSKSKVSSQFDPNKQTPSGKKCIAAKKIKQSV 837
K ++P P + P K KV P K KK + KK+ V
Sbjct: 9570 AKIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKV----PPPKVPEEPKKPVPEKKVPPKV 9625
Query: 838 GNKSMSFPTGKSDR 851
P ++R
Sbjct: 9626 IKMEEPLPAKVTER 9639
>gi|92859701 myosin VI [Homo sapiens]
Length = 1285
Score = 36.2 bits (82), Expect = 0.13
Identities = 32/139 (23%), Positives = 67/139 (48%), Gaps = 11/139 (7%)
Query: 679 KKAQNIMESFENPFRMISNRWKLAQVQVQKDSKEAVKKKAAEQTAAREQAKEACKAAAEQ 738
K+ +N+ S + I + + Q Q+QK+ VK ++E+ + Q K+ + AE
Sbjct: 869 KQIKNLEISIDTLMAKIKSTM-MTQEQIQKEYDALVK--SSEELLSALQKKKQQEEEAE- 924
Query: 739 AISVRQQVVLENAAKKRERATSDPRTTEQKQEKKRLKI---SKKPKDPEPPEKEFTPYDY 795
R + + E K+R+R D + +++E++R+K+ +K+ ++ E +K
Sbjct: 925 ----RLRRIQEEMEKERKRREEDEKRRRKEEEERRMKLEMEAKRKQEEEERKKREDDEKR 980
Query: 796 SQSDFKAFAGNSKSKVSSQ 814
Q++ +A K + S Q
Sbjct: 981 IQAEVEAQLARQKEEESQQ 999
>gi|126090663 zinc finger homeodomain 4 [Homo sapiens]
Length = 3571
Score = 36.2 bits (82), Expect = 0.13
Identities = 22/73 (30%), Positives = 37/73 (50%), Gaps = 2/73 (2%)
Query: 204 IKPNAQKPLPQALSKERRERPQDRPEDLDVPPALADFIHQQRTQQVEQDMFAHPYQYELN 263
+K QKP + L E E ++ +D+ +P L D +++Q+ +Q H Y+Y N
Sbjct: 1298 VKNEEQKPTKEPL--EVSEWNKNSSKDVKIPDTLQDQLNEQQKRQPLSVSDRHVYKYRCN 1355
Query: 264 HFTPADAVLQKPQ 276
H + A +QK Q
Sbjct: 1356 HCSLAFKTMQKLQ 1368
>gi|110349717 titin isoform novex-2 [Homo sapiens]
Length = 27118
Score = 35.8 bits (81), Expect = 0.17
Identities = 21/58 (36%), Positives = 31/58 (53%), Gaps = 6/58 (10%)
Query: 729 KEACKAAAEQAISVRQQVVLENAAKKRERATSDPRTTEQKQEKKRLKISKKPKDPEPP 786
K+ K E+ +++VVL++ +KR P E K E K+L+ KKP PEPP
Sbjct: 4625 KKVRKLLPERKPEPKEEVVLKSVLRKR------PEEEEPKVEPKKLEKVKKPAVPEPP 4676
>gi|110349713 titin isoform novex-1 [Homo sapiens]
Length = 27051
Score = 35.8 bits (81), Expect = 0.17
Identities = 21/58 (36%), Positives = 31/58 (53%), Gaps = 6/58 (10%)
Query: 729 KEACKAAAEQAISVRQQVVLENAAKKRERATSDPRTTEQKQEKKRLKISKKPKDPEPP 786
K+ K E+ +++VVL++ +KR P E K E K+L+ KKP PEPP
Sbjct: 4558 KKVRKLLPERKPEPKEEVVLKSVLRKR------PEEEEPKVEPKKLEKVKKPAVPEPP 4609
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.390
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,138,704
Number of Sequences: 37866
Number of extensions: 1641419
Number of successful extensions: 7358
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 50
Number of HSP's successfully gapped in prelim test: 206
Number of HSP's that attempted gapping in prelim test: 6501
Number of HSP's gapped (non-prelim): 940
length of query: 860
length of database: 18,247,518
effective HSP length: 111
effective length of query: 749
effective length of database: 14,044,392
effective search space: 10519249608
effective search space used: 10519249608
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.