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Search of human proteins with 4505021
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4505021 low density lipoprotein receptor-related protein
associated protein 1 precursor [Homo sapiens]
(357 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4505021 low density lipoprotein receptor-related protein asso... 717 0.0
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens] 45 8e-05
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 44 2e-04
gi|239757009 PREDICTED: ankyrin repeat domain 20 family, member ... 44 2e-04
gi|239751523 PREDICTED: ankyrin repeat domain 20 family, member ... 44 2e-04
gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens] 43 4e-04
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 42 6e-04
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 42 8e-04
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 42 8e-04
gi|38044112 restin isoform b [Homo sapiens] 42 8e-04
gi|4506751 restin isoform a [Homo sapiens] 42 8e-04
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 42 0.001
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 42 0.001
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens] 41 0.002
gi|56961680 coiled-coil domain containing 147 [Homo sapiens] 40 0.002
gi|42740899 CTAGE family, member 5 isoform 3 [Homo sapiens] 40 0.003
gi|42740897 CTAGE family, member 5 isoform 1 [Homo sapiens] 40 0.003
gi|42740901 CTAGE family, member 5 isoform 4 [Homo sapiens] 40 0.003
gi|42740905 CTAGE family, member 5 isoform 2 [Homo sapiens] 40 0.003
gi|81295809 pericentrin [Homo sapiens] 40 0.004
gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens] 40 0.004
gi|23097308 spectrin repeat containing, nuclear envelope 1 isofo... 39 0.007
gi|154277116 spectrin repeat containing, nuclear envelope 1 isof... 39 0.007
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 39 0.009
gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens] 38 0.012
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 38 0.016
gi|29171753 PTPRF interacting protein alpha 1 isoform a [Homo sa... 37 0.021
gi|4505983 PTPRF interacting protein alpha 1 isoform b [Homo sap... 37 0.021
gi|66773344 hypothetical protein LOC140710 [Homo sapiens] 36 0.046
gi|32455252 phosphoinositide-3-kinase, regulatory subunit 1 (alp... 36 0.061
>gi|4505021 low density lipoprotein receptor-related protein
associated protein 1 precursor [Homo sapiens]
Length = 357
Score = 717 bits (1850), Expect = 0.0
Identities = 357/357 (100%), Positives = 357/357 (100%)
Query: 1 MAPRRVRSFLRGLPALLLLLLFLGPWPAASHGGKYSREKNQPKPSPKRESGEEFRMEKLN 60
MAPRRVRSFLRGLPALLLLLLFLGPWPAASHGGKYSREKNQPKPSPKRESGEEFRMEKLN
Sbjct: 1 MAPRRVRSFLRGLPALLLLLLFLGPWPAASHGGKYSREKNQPKPSPKRESGEEFRMEKLN 60
Query: 61 QLWEKAQRLHLPPVRLAELHADLKIQERDELAWKKLKLDGLDEDGEKEARLIRNLNVILA 120
QLWEKAQRLHLPPVRLAELHADLKIQERDELAWKKLKLDGLDEDGEKEARLIRNLNVILA
Sbjct: 61 QLWEKAQRLHLPPVRLAELHADLKIQERDELAWKKLKLDGLDEDGEKEARLIRNLNVILA 120
Query: 121 KYGLDGKKDARQVTSNSLSGTQEDGLDDPRLEKLWHKAKTSGKFSGEELDKLWREFLHHK 180
KYGLDGKKDARQVTSNSLSGTQEDGLDDPRLEKLWHKAKTSGKFSGEELDKLWREFLHHK
Sbjct: 121 KYGLDGKKDARQVTSNSLSGTQEDGLDDPRLEKLWHKAKTSGKFSGEELDKLWREFLHHK 180
Query: 181 EKVHEYNVLLETLSRTEEIHENVISPSDLSDIKGSVLHSRHTELKEKLRSINQGLDRLRR 240
EKVHEYNVLLETLSRTEEIHENVISPSDLSDIKGSVLHSRHTELKEKLRSINQGLDRLRR
Sbjct: 181 EKVHEYNVLLETLSRTEEIHENVISPSDLSDIKGSVLHSRHTELKEKLRSINQGLDRLRR 240
Query: 241 VSHQGYSTEAEFEEPRVIDLWDLAQSANLTDKELEAFREELKHFEAKIEKHNHYQKQLEI 300
VSHQGYSTEAEFEEPRVIDLWDLAQSANLTDKELEAFREELKHFEAKIEKHNHYQKQLEI
Sbjct: 241 VSHQGYSTEAEFEEPRVIDLWDLAQSANLTDKELEAFREELKHFEAKIEKHNHYQKQLEI 300
Query: 301 AHEKLRHAESVGDGERVSRSREKHALLEGRTKELGYTVKKHLQDLSGRISRARHNEL 357
AHEKLRHAESVGDGERVSRSREKHALLEGRTKELGYTVKKHLQDLSGRISRARHNEL
Sbjct: 301 AHEKLRHAESVGDGERVSRSREKHALLEGRTKELGYTVKKHLQDLSGRISRARHNEL 357
>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
Length = 3899
Score = 45.4 bits (106), Expect = 8e-05
Identities = 63/282 (22%), Positives = 128/282 (45%), Gaps = 11/282 (3%)
Query: 36 SREKNQPKPSPKRESGE--EFRMEKLNQLWEKAQRLHLPPVRLA-ELHADLKIQ-ERDEL 91
S+E+ Q + E E EFR+ +L Q R H V EL ++++Q ERD +
Sbjct: 2131 SKEQLQRDIQERNEEIEKLEFRVRELEQALLVEDRKHFGAVEAKPELSLEVQLQAERDAI 2190
Query: 92 AWKKLKLDGLDEDGEKEARLIRNLNVILAKYGLDGKKDARQVTSNSLSGTQEDGLDDPRL 151
K+ ++ L+E E+ + N N + + + + ++ T+ QE+ L +
Sbjct: 2191 DRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDM 2250
Query: 152 EKLWHKAKTSGKFSGEELDKLWREFLH-HKEKVHEYNVLLETLSRTEEIHENVISPSDLS 210
EKL K S S ++ L+ +F +EK E + L E +++ ++ + + + +
Sbjct: 2251 EKLGLAIKESDAMSTQDQHVLFGKFAQIIQEKEVEIDQLNEQVTKLQQ-QLKITTDNKVI 2309
Query: 211 DIKGSVLHSRHTELKEKLRSINQGLDRLRRVSHQGYSTEAEFEEPRVIDLWDLAQSANLT 270
+ K ++ T++ E L S + + R R + + E E +L ++ Q ++
Sbjct: 2310 EEKNELIRDLETQI-ECLMSDQECVKRNREEEIEQLN---EVIEKLQQELANIGQKTSMN 2365
Query: 271 DKELEAFREELKH-FEAKIEKHNHYQKQLEIAHEKLRHAESV 311
L + LKH + I + ++Q+E A+E++ ++V
Sbjct: 2366 AHSLSEEADSLKHQLDVVIAEKLALEQQVETANEEMTFMKNV 2407
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 44.3 bits (103), Expect = 2e-04
Identities = 55/307 (17%), Positives = 130/307 (42%), Gaps = 43/307 (14%)
Query: 38 EKNQPKPSPKRESGEEFRMEKLNQLWEKAQRLHLPPVRLAE-LHADLKIQERDELAWKKL 96
EK + + E E+ R ++ +WEK +++ L E +H KI+E++E ++
Sbjct: 363 EKMRRQEEMMWEKEEKMRRQE-EMMWEKEEKIR----ELEEKMHEQEKIREQEEKRQEEE 417
Query: 97 KLDGLDEDGEKEARLIRNLNVILAKYGLDGKKDARQVTSNSLSGTQEDGLDDPRLEKLWH 156
K+ ++ E+EA++ R I ++ ++ +++ EK+
Sbjct: 418 KIREQEKRQEQEAKMWRQEEKI--------REQEEKIREQEKKMWRQE-------EKIHE 462
Query: 157 KAKTSGKFSGEELDKLWREFLHHKEKVHEYNVLLETLSRTEEIHENVISPSDLSDIKGSV 216
+ K + +E +++WR+ +EK+HE + + E E + + +
Sbjct: 463 QEKIREEEKRQEQEEMWRQ----EEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEK 518
Query: 217 LHSRHTELKEKLRSINQGLDRLRRVSHQGYSTEAEFEEPRVID----------LWDLAQS 266
+ + +++E+ + + +++R E E+ ++ + +W Q
Sbjct: 519 IREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMW--RQE 576
Query: 267 ANLTDKELEAFREELKHFEAKIEKHNHYQKQLEIAHEKLRHAESVGDGERVSRSREKHAL 326
+ ++E + +R+E K E + EK ++++ EK+R E E++ EK
Sbjct: 577 EKIREQEEKVWRQEEKIREQE-EKRQEQEEKMWKQEEKIREQE-----EKIQEQEEKIRE 630
Query: 327 LEGRTKE 333
E + +E
Sbjct: 631 QEEKIRE 637
Score = 30.8 bits (68), Expect = 1.9
Identities = 52/310 (16%), Positives = 118/310 (38%), Gaps = 65/310 (20%)
Query: 31 HGGKYSREKNQPKPSPKRESGEEFRMEKLNQLWEKAQRLHLPPVRLAE-----------L 79
H + RE+ + + ++ +E R E+ ++W + +++ ++ E +
Sbjct: 401 HEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKI 460
Query: 80 HADLKI------QERDELAWKKLKLDGLDEDGEKEARLIRNLNVILAKYGLDGKKDARQV 133
H KI QE++E+ ++ K+ +E ++ ++ I +K +V
Sbjct: 461 HEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKI--------RKQEEKV 512
Query: 134 TSNSLSGTQEDGLDDPRLEKLWHKAKTSGKFSGEELDKLWREFLHHKEKVHEYNVLLETL 193
+++ + EK+W + + E +++WRE +EK+HE + E
Sbjct: 513 WRQEEKIREQEEKIREQEEKMWRQEEKI-----REQEEMWRE----EEKMHEQEKIWEEE 563
Query: 194 SRTEEIHENVISPSDLSDIKGSVLHSRHTELKEKLRSINQGLDRLRRVSHQGYSTEAEFE 253
R E+ + +EK+R + + R + E E
Sbjct: 564 KRQEQ-------------------EDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQE 604
Query: 254 EPRVIDLWDLAQSANLTDKELEAFREELKHFEAKIEKHNHYQKQLEIAHEKLRHAESVGD 313
E +W + +++++ E+++ E KI + ++ E EK+ E
Sbjct: 605 E----KMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQE---EKMGEQE---- 653
Query: 314 GERVSRSREK 323
E++ EK
Sbjct: 654 -EKMCEQEEK 662
>gi|239757009 PREDICTED: ankyrin repeat domain 20 family, member A5
[Homo sapiens]
Length = 823
Score = 44.3 bits (103), Expect = 2e-04
Identities = 59/259 (22%), Positives = 113/259 (43%), Gaps = 24/259 (9%)
Query: 96 LKLDGLDEDGE--KEARLIRNLNVILAKYGLDGKKDARQVTSNSLSGTQEDG---LDDPR 150
+K D L+++ + K+ ++ + N L K K + +T + QE ++ R
Sbjct: 531 MKNDNLEKENKYLKDIKIAKETNAALEKCI---KLNEEMITKTAFWYQQELNDLKAENTR 587
Query: 151 LEKLWHKAKTSGKFSGEELD----KLWREFLHHKEKVHEYNVLLETLSRTEEIHENVISP 206
L K K S K E++ +L H E V L L RT++I E V
Sbjct: 588 LNSELLKEKESKKKLEAEIESYQSRLAAAISKHSENVKTERNLKLALERTQDISEQVKMS 647
Query: 207 SDLSDIKG---------SVLHSRHTELKEKLRSINQGLDRLRRVSHQGYSTEAEFEEPRV 257
SD+S+I+ S + + LK+K R L R + ++ + + + ++
Sbjct: 648 SDISEIEDKNXFLTEQLSKMQIKFNTLKDKFRKTRDTL-RKKSLALETVQNDLSQTQQQI 706
Query: 258 IDLWDLAQSANLTDKELEAFREELKHFEAKIEKHNHY-QKQLEIAHEKLRHAESVGDGER 316
++ ++ QSA + ++ ++++ N + ++QL H+K H E V + +R
Sbjct: 707 KEMKEMYQSAEAKVSKSTGKWNCVEERICQLQRENPWLEQQLVDVHQKEDHKEIVINIQR 766
Query: 317 -VSRSREKHALLEGRTKEL 334
SR+K +LE + K+L
Sbjct: 767 GFIESRKKDLMLEEKNKKL 785
>gi|239751523 PREDICTED: ankyrin repeat domain 20 family, member A5
[Homo sapiens]
Length = 823
Score = 44.3 bits (103), Expect = 2e-04
Identities = 59/259 (22%), Positives = 113/259 (43%), Gaps = 24/259 (9%)
Query: 96 LKLDGLDEDGE--KEARLIRNLNVILAKYGLDGKKDARQVTSNSLSGTQEDG---LDDPR 150
+K D L+++ + K+ ++ + N L K K + +T + QE ++ R
Sbjct: 531 MKNDNLEKENKYLKDIKIAKETNAALEKCI---KLNEEMITKTAFWYQQELNDLKAENTR 587
Query: 151 LEKLWHKAKTSGKFSGEELD----KLWREFLHHKEKVHEYNVLLETLSRTEEIHENVISP 206
L K K S K E++ +L H E V L L RT++I E V
Sbjct: 588 LNSELLKEKESKKKLEAEIESYQSRLAAAISKHSENVKTERNLKLALERTQDISEQVKMS 647
Query: 207 SDLSDIKG---------SVLHSRHTELKEKLRSINQGLDRLRRVSHQGYSTEAEFEEPRV 257
SD+S+I+ S + + LK+K R L R + ++ + + + ++
Sbjct: 648 SDISEIEDKNXFLTEQLSKMQIKFNTLKDKFRKTRDTL-RKKSLALETVQNDLSQTQQQI 706
Query: 258 IDLWDLAQSANLTDKELEAFREELKHFEAKIEKHNHY-QKQLEIAHEKLRHAESVGDGER 316
++ ++ QSA + ++ ++++ N + ++QL H+K H E V + +R
Sbjct: 707 KEMKEMYQSAEAKVSKSTGKWNCVEERICQLQRENPWLEQQLVDVHQKEDHKEIVINIQR 766
Query: 317 -VSRSREKHALLEGRTKEL 334
SR+K +LE + K+L
Sbjct: 767 GFIESRKKDLMLEEKNKKL 785
>gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]
Length = 1317
Score = 43.1 bits (100), Expect = 4e-04
Identities = 82/366 (22%), Positives = 150/366 (40%), Gaps = 70/366 (19%)
Query: 37 REKNQPKPSPKRESGEEF--------RMEKLNQLWEKAQRLHLPPVRLAELHADLKIQER 88
RE+ + + KR+ E F R+++LN EKA++ + EL D +E+
Sbjct: 685 REQQEIELQKKRQEEETFLRVQEELQRLKELNNN-EKAEKFQI----FQEL--DQLQKEK 737
Query: 89 DELAWKKLKLDG--LDEDGEKEARLIRNLNVILAKYGLDGKKDARQVTSNS-LSGTQEDG 145
DE + KL+L+ L+E +++ L+ +L L + K++ Q+ + +E+
Sbjct: 738 DE-QYAKLELEKKRLEEQEKEQVMLVAHLEEQLRE-----KQEMIQLLRRGEVQWVEEEK 791
Query: 146 LDDPRLEKLW---HKAKTSGKFSGEELDKLWREFLHHKEK------------VHEYNVLL 190
D + + +A+ G GEEL+K F K + V + ++L
Sbjct: 792 RDLEGIRESLLRVKEARAGGDEDGEELEKAQLRFFEFKRRQLVKLVNLEKDLVQQKDILK 851
Query: 191 ETLSRTEEIHENVISPSDLSDIKGSVLHSRHTELKEKLRSINQGLDRLRRVSHQGYSTEA 250
+ + +EI E + D K S L +H E + + Q ++++ V ++ E
Sbjct: 852 KEVQEEQEILECLKCEHD----KESRLLEKHDESVTDVTEVPQDFEKIKPVEYRLQYKER 907
Query: 251 EF-------------EEPRVIDLWD-----LAQSANLTDKELEAFREELKHFEAKIEKHN 292
+ E+ R ++ D L + +KE+E E+L ++A +
Sbjct: 908 QLQYLLQNHLPTLLEEKQRAFEILDRGPLSLDNTLYQVEKEMEEKEEQLAQYQANANQLQ 967
Query: 293 HYQKQLEIAHEKLRHAESVGDGERVSRSREKHALLEGRTKELGYTVKKHLQDLSGRISR- 351
Q E R E V R +EK +LE R K+ +++ L L R S
Sbjct: 968 KLQATFEFTANIARQEEKV-------RKKEKE-ILESREKQQREALERALARLERRHSAL 1019
Query: 352 ARHNEL 357
RH+ L
Sbjct: 1020 QRHSTL 1025
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 42.4 bits (98), Expect = 6e-04
Identities = 63/329 (19%), Positives = 132/329 (40%), Gaps = 31/329 (9%)
Query: 38 EKNQPKPSPKRESGEEFRMEKLNQLWEKAQRLHLPPVRLAE-LHADLKIQERDELAWKKL 96
EK + + E E+ R ++ +WEK +++ L E +H KI+E++E ++
Sbjct: 410 EKMRRQEEMMWEKEEKMRRQE-EMMWEKEEKIR----ELEEKMHEQEKIREQEEKRQEEE 464
Query: 97 KLDGLDEDGEKEARLIRNLNVILAKYGLDGKKDARQVTSNSLSGTQEDGLDDPR---LEK 153
K+ ++ E+EA++ R I + +++ + QE ++ + E+
Sbjct: 465 KIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEE 524
Query: 154 LWHKAKTSGKFSGEELDKLWREFLHHKEKVHEYNVLL----ETLSRTEEIHENVISPSDL 209
+W + + E +++WR+ KEK+HE + E + R EE +
Sbjct: 525 MWRQEEKI-----REQEEIWRQ----KEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIRE 575
Query: 210 SDIKGSVLHSRHTELKEKLRSINQGLDRLRRVSHQGYSTEAEFEEPRVIDLWDLAQSANL 269
+ K + E +EK+R + + ++ + E EE + +
Sbjct: 576 QEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEK 635
Query: 270 TDKELEAFREELKHFEAKIEKHNHYQKQLEIAHEKLRHAES---------VGDGERVSRS 320
++ E RE+ K + EK ++ ++ EK+ E E++ R
Sbjct: 636 MRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQ 695
Query: 321 REKHALLEGRTKELGYTVKKHLQDLSGRI 349
EK E R ++ +++H + L I
Sbjct: 696 EEKMWEQEVRLRQQEEKMQEHQEHLEAAI 724
Score = 32.7 bits (73), Expect = 0.51
Identities = 46/289 (15%), Positives = 121/289 (41%), Gaps = 23/289 (7%)
Query: 31 HGGKYSREKNQPKPSPKRESGEEFRMEKLNQLWEKAQRLHLPPVRLAELHADLKIQERDE 90
H + RE+ + + ++ +E R E+ ++W + +++ + KI+E++E
Sbjct: 448 HEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIR---------EQEEKIREQEE 498
Query: 91 LAWK-KLKLDGLDEDGEKEARLIRNLNVILAKYGLDGK-KDARQVTSNSLSGTQEDGLDD 148
W+ + K+ ++ E+E R + + + K ++ ++ +++
Sbjct: 499 KMWRQEEKIHEQEKIREEEKRQEQE-----EMWRQEEKIREQEEIWRQKEKIHEQEEKIR 553
Query: 149 PRLEKLW---HKAKTSGKFSGEELDKLWREFLHHKEKVHEYNVLLETLSRTEEIHENVIS 205
+ EK+W K + E+ +K+WR+ +E+ + E + EE+ +
Sbjct: 554 KQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEE 613
Query: 206 PSDLSDIKGSVLHSRHTELKEKLRSINQGL---DRLRRVSHQGYSTEAEFEEPRVIDLWD 262
+ K + E +EK+R + + ++ R + + E + + +W+
Sbjct: 614 KMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWE 673
Query: 263 LAQSANLTDKELEAFREELKHFEAKI-EKHNHYQKQLEIAHEKLRHAES 310
+ +++++ E+++ E K+ E+ ++Q E E H E+
Sbjct: 674 QEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEA 722
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 42.0 bits (97), Expect = 8e-04
Identities = 55/312 (17%), Positives = 131/312 (41%), Gaps = 25/312 (8%)
Query: 52 EEFRMEKLNQL-WEKAQRLHLPPVRLAE-LHADLKIQERDELAWKKLKLDGLDEDGEKEA 109
+E +M +L ++ WEK +++ L E +H KI+E++E ++ K+ ++ E+EA
Sbjct: 361 KEEKMRRLEEMMWEKEEKIR----ELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEA 416
Query: 110 RLIRNLNVILAKYGLDGKKDARQVTSNSLSGTQEDGLDDPR---LEKLWHKAKTSGKFSG 166
++ R I + +++ + QE ++ + E++W + +
Sbjct: 417 KMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKI----- 471
Query: 167 EELDKLWREFLHHKEKVHEYNVLLETLSRTEEIHENVISPSDLSDIKGSVLHSRHTELKE 226
E +++WR+ KEK+HE + + + E + + + + + +++E
Sbjct: 472 REQEEIWRQ----KEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIRE 527
Query: 227 KLRSINQGLDRLRRVSHQGYSTEAEFEEPRVIDLWDLAQSANLTDKELEAFREELKHFEA 286
+ I + +++R E + E + Q ++ E RE+ +
Sbjct: 528 QEEKIREQEEKIREQEEMMQEQEEKMGEQE-----EKMQEQEKMRRQEEKIREQEEKIRE 582
Query: 287 KIEKHNHYQKQLEIAHEKLRHAESV--GDGERVSRSREKHALLEGRTKELGYTVKKHLQD 344
+ EK ++++ EK+R E + E++ EK E + +E +++ +
Sbjct: 583 QKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEK 642
Query: 345 LSGRISRARHNE 356
+ + R R E
Sbjct: 643 MWEQEVRLRQQE 654
Score = 32.3 bits (72), Expect = 0.67
Identities = 44/294 (14%), Positives = 118/294 (40%), Gaps = 28/294 (9%)
Query: 31 HGGKYSREKNQPKPSPKRESGEEFRMEKLNQLWEKAQRLHLPPVRLAELHADLKIQERDE 90
H + RE+ + + ++ +E R E+ ++W + +++ + KI+E+++
Sbjct: 387 HEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIR---------EQEEKIREQEK 437
Query: 91 LAWK-KLKLDGLDEDGEKEARLIRNLNVILAKYGLDGKKDARQVTSNSLSGTQEDGLDDP 149
W+ + K+ ++ E+E R + + + K ++ E
Sbjct: 438 KMWRQEEKIHEQEKIREEEKRQEQE-----EMWRQEEKIREQEEIWRQKEKMHEQEKIRK 492
Query: 150 RLEKLW---HKAKTSGKFSGEELDKLWRE---FLHHKEKVHEYNVLLETLSRTEEIHENV 203
+ EK+W K + E+ +K+WR+ +EK+ E + + E
Sbjct: 493 QEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEK 552
Query: 204 ISPSDLSDIKGSVLHSRHTELKEKLRSINQGLDRLRRVSHQGYSTEAEFEEPRVI----- 258
+ + + + + +++E+ I + +++R + + E + E +
Sbjct: 553 MGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQE 612
Query: 259 -DLWDLAQSANLTDKELEAFREELKHFEAKI-EKHNHYQKQLEIAHEKLRHAES 310
+W+ + +++++ E+++ E K+ E+ ++Q E E H E+
Sbjct: 613 EKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEA 666
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 42.0 bits (97), Expect = 8e-04
Identities = 51/292 (17%), Positives = 129/292 (44%), Gaps = 16/292 (5%)
Query: 37 REKNQPKPSPKRESGEEFRMEKLNQLWEKAQRLHLPPVRL--AELHADLKIQERDELAW- 93
R++ + K+ +E E+ +Q+WE+ +++ ++ E + K QE+++ W
Sbjct: 521 RDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWD 580
Query: 94 KKLKLDGLDEDGEKEARLIRNLNVILAKYGLDGKKDARQVTSNSLSGTQEDGLDDPRLEK 153
++ K+ + E+E ++ ++ + +++ + QE+ + + EK
Sbjct: 581 QEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQE-EK 639
Query: 154 LWHKAKTSGKFSGEELDKLWRE--FLHHKEKVHEYNVLLETLSRTEEIHENVISPSDLSD 211
+W + + E+ +K+W + KEK+ E+ + E + +E E + +
Sbjct: 640 MWEQEEKMW----EQEEKMWEQQRLPEQKEKLWEHEKMQEQ-EKMQEQEEKIWEQEKME- 693
Query: 212 IKGSVLHSRHTELKEKLRSINQGLDRLRRVSHQGYSTEAEFEEPRVIDLWDLAQSANLTD 271
K + + T +EK+R +R +++ + + E+ + + Q + +
Sbjct: 694 -KKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWE 752
Query: 272 KELEAFREELKHFEAKIEKHNHYQKQLEIAHEKLRHAESVGDGERVSRSREK 323
+E + + +E K +E ++ QK+ HEK++ E + + E R +E+
Sbjct: 753 QEEKMWEQEEKMWE---QQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEE 801
Score = 40.8 bits (94), Expect = 0.002
Identities = 56/289 (19%), Positives = 127/289 (43%), Gaps = 27/289 (9%)
Query: 38 EKNQPKPSPKRESGEEFRMEKLNQLWEKAQRLHLPPVRLAELHADLKIQERDELAWKKL- 96
E+ + K + EE E+ + W++ QRL P + +L K+QE++E W++
Sbjct: 463 EETMREQEEKMQKQEENMWEQEEKEWQQ-QRL---PEQKEKLWEQEKMQEQEEKIWEQEE 518
Query: 97 KLDGLDEDGEKEARLIRNLNVILAKYGLDGKKDARQVTSNSLSGTQEDGLDDPRLEKLWH 156
K+ +E +E ++ R + ++ Q+ QE+ + D +K+W
Sbjct: 519 KIRDQEEMWGQEKKMWRQEKM---------REQEDQMWE------QEEKMRDQE-QKMWD 562
Query: 157 KAKTSGKFSGEELDKLWREFLHHKEKVHEYNVLLETLSRTEEIHENVISPSDLSDIKGSV 216
+ + K + E+ K W + +EK+ E + E + E E + + +
Sbjct: 563 QEERMEKKTQEQEKKTWDQ----EEKMREEERMREREKKMREEEEMMREQEEKMQEQEEK 618
Query: 217 LHSRHTELKEKLRSINQGLDRLRRVSHQGYSTEAE-FEEPRVIDLWD-LAQSANLTDKEL 274
+ + ++ E+ + + +++ + + E + +E+ R+ + + L + + ++E
Sbjct: 619 MQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEK 678
Query: 275 EAFREELKHFEAKIEKHNHYQKQLEIAHEKLRHAESVGDGERVSRSREK 323
+EE + K+EK Q++ EK+R ES+ + E+ R E+
Sbjct: 679 MQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEE 727
Score = 28.9 bits (63), Expect = 7.4
Identities = 48/287 (16%), Positives = 115/287 (40%), Gaps = 29/287 (10%)
Query: 37 REKNQPKPSPKRESGEEFRMEKLNQLWEKAQRLHLPPVRLAELHADLKIQERDELAWKKL 96
+E+ + K EE E+ ++W + +RL ++ E + K+++++E W++
Sbjct: 346 QEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMRE--QEQKMRDQEERMWEQ- 402
Query: 97 KLDGLDEDGEKEARLIRNLNVILAKYGLDGKKDARQVTSNSLSGTQEDGLDDPRLEKLWH 156
DE ++ +R + + ++ Q +E ++ R+ +
Sbjct: 403 -----DERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREK 457
Query: 157 KAKTSGKFSGEELDKLWREFLHHKEKVHEYNVLLETLSRTEEIHENVISPSDLSDIKGSV 216
K + + E+ +K+ ++ +E + E R E E + + + + +
Sbjct: 458 KMREEEETMREQEEKMQKQ----EENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKI 513
Query: 217 LHSRHTELKEKLRSINQGLDRLRRVSHQGYSTEAEFEEPRVIDLWDLAQSANLTDKELEA 276
E +EK+R + + +++ Q E E + +W+ Q + D+E +
Sbjct: 514 -----WEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQ------MWE--QEEKMRDQEQKM 560
Query: 277 FREELKHFEAKIEKHNHYQKQLEIAHEKLRHAESVGDGERVSRSREK 323
+ +E E +K +K+ EK+R E + + E+ R E+
Sbjct: 561 WDQE----ERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEE 603
>gi|38044112 restin isoform b [Homo sapiens]
Length = 1392
Score = 42.0 bits (97), Expect = 8e-04
Identities = 61/258 (23%), Positives = 115/258 (44%), Gaps = 17/258 (6%)
Query: 99 DGLDEDGEKEARLIRNLNVILAKYGLDGKKDARQVTSNSLSGTQEDGLDDPRLEKLWHKA 158
D L++ E E + ++ L V+ AK + K TS L T+E LD L K +
Sbjct: 684 DTLNKLQEAEIK-VKELEVLQAKCN-EQTKVIDNFTSQ-LKATEEKLLDLDALRKASSEG 740
Query: 159 KTSGKFSGEELDKLWREFLHHK-EKVHEYNVLLETLSRTEEIHENVISPSDLSDIKGSVL 217
K+ K ++L+ ++ H + EK E + + S T E+ + ++L + V
Sbjct: 741 KSEMKKLRQQLEAAEKQIKHLEIEKNAESS---KASSITRELQGRELKLTNLQENLSEVS 797
Query: 218 HSRHTELKEKLRSINQGLDRLRRVSHQGYSTEAEFEEPRVIDLWDLAQSANLTDKELEAF 277
+ T L+++L+ + + + S + S + +E V L + N+ +LE
Sbjct: 798 QVKET-LEKELQILKE---KFAEASEEAVSVQRSMQET-VNKLHQKEEQFNMLSSDLEKL 852
Query: 278 REELKHFEAKIEKHNHYQKQLEIAHEKLRHAESVGDGERVSRSREKHALLEGRTKELGYT 337
RE L EAK + + ++QL A EKL + E + S + + L EL
Sbjct: 853 RENLADMEAKFREKDEREEQLIKAKEKLEN----DIAEIMKMSGDNSSQLTKMNDELRLK 908
Query: 338 VKKHLQDLSGRISRARHN 355
++ +++L ++++A N
Sbjct: 909 -ERDVEELQLKLTKANEN 925
Score = 32.0 bits (71), Expect = 0.87
Identities = 33/173 (19%), Positives = 77/173 (44%), Gaps = 13/173 (7%)
Query: 180 KEKVHEYNVLLETLSRTEEIHENVISPSDLSDIKGSVLHSRHTELKEKLRSINQGLDRLR 239
KEK + + L + E+ H L +++ ++ + E+K K + Q +
Sbjct: 658 KEKENSLEAIRSKLDKAEDQH--------LVEMEDTLNKLQEAEIKVKELEVLQAKCNEQ 709
Query: 240 RVSHQGYSTEAEFEEPRVIDLWDLAQSANLTDKELEAFREELKHFEAKIEKHNHYQKQLE 299
++++ + E +++DL L ++++ E++ R++L+ E +I KH +K E
Sbjct: 710 TKVIDNFTSQLKATEEKLLDLDALRKASSEGKSEMKKLRQQLEAAEKQI-KHLEIEKNAE 768
Query: 300 IAHEKLRHAESVGDGERVSRSREKHALLEGRTKELGYTVKKHLQDLSGRISRA 352
+ E G +++ +E + ++ T++K LQ L + + A
Sbjct: 769 SSKASSITRELQGRELKLTNLQENLS----EVSQVKETLEKELQILKEKFAEA 817
>gi|4506751 restin isoform a [Homo sapiens]
Length = 1427
Score = 42.0 bits (97), Expect = 8e-04
Identities = 61/258 (23%), Positives = 115/258 (44%), Gaps = 17/258 (6%)
Query: 99 DGLDEDGEKEARLIRNLNVILAKYGLDGKKDARQVTSNSLSGTQEDGLDDPRLEKLWHKA 158
D L++ E E + ++ L V+ AK + K TS L T+E LD L K +
Sbjct: 719 DTLNKLQEAEIK-VKELEVLQAKCN-EQTKVIDNFTSQ-LKATEEKLLDLDALRKASSEG 775
Query: 159 KTSGKFSGEELDKLWREFLHHK-EKVHEYNVLLETLSRTEEIHENVISPSDLSDIKGSVL 217
K+ K ++L+ ++ H + EK E + + S T E+ + ++L + V
Sbjct: 776 KSEMKKLRQQLEAAEKQIKHLEIEKNAESS---KASSITRELQGRELKLTNLQENLSEVS 832
Query: 218 HSRHTELKEKLRSINQGLDRLRRVSHQGYSTEAEFEEPRVIDLWDLAQSANLTDKELEAF 277
+ T L+++L+ + + + S + S + +E V L + N+ +LE
Sbjct: 833 QVKET-LEKELQILKE---KFAEASEEAVSVQRSMQET-VNKLHQKEEQFNMLSSDLEKL 887
Query: 278 REELKHFEAKIEKHNHYQKQLEIAHEKLRHAESVGDGERVSRSREKHALLEGRTKELGYT 337
RE L EAK + + ++QL A EKL + E + S + + L EL
Sbjct: 888 RENLADMEAKFREKDEREEQLIKAKEKLEN----DIAEIMKMSGDNSSQLTKMNDELRLK 943
Query: 338 VKKHLQDLSGRISRARHN 355
++ +++L ++++A N
Sbjct: 944 -ERDVEELQLKLTKANEN 960
Score = 32.0 bits (71), Expect = 0.87
Identities = 33/173 (19%), Positives = 77/173 (44%), Gaps = 13/173 (7%)
Query: 180 KEKVHEYNVLLETLSRTEEIHENVISPSDLSDIKGSVLHSRHTELKEKLRSINQGLDRLR 239
KEK + + L + E+ H L +++ ++ + E+K K + Q +
Sbjct: 693 KEKENSLEAIRSKLDKAEDQH--------LVEMEDTLNKLQEAEIKVKELEVLQAKCNEQ 744
Query: 240 RVSHQGYSTEAEFEEPRVIDLWDLAQSANLTDKELEAFREELKHFEAKIEKHNHYQKQLE 299
++++ + E +++DL L ++++ E++ R++L+ E +I KH +K E
Sbjct: 745 TKVIDNFTSQLKATEEKLLDLDALRKASSEGKSEMKKLRQQLEAAEKQI-KHLEIEKNAE 803
Query: 300 IAHEKLRHAESVGDGERVSRSREKHALLEGRTKELGYTVKKHLQDLSGRISRA 352
+ E G +++ +E + ++ T++K LQ L + + A
Sbjct: 804 SSKASSITRELQGRELKLTNLQENLS----EVSQVKETLEKELQILKEKFAEA 852
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 41.6 bits (96), Expect = 0.001
Identities = 50/276 (18%), Positives = 122/276 (44%), Gaps = 18/276 (6%)
Query: 61 QLWEKAQRLHLPPVRLAELHADLKIQERDELAWKKLKLDGLDEDG--EKEARLIRNLNVI 118
++W + +++ ++ E +LKI+E++E W++ + E+ E+E ++ R I
Sbjct: 298 KMWRQEEKIQEQEEKMCE--QELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKI 355
Query: 119 LAKYGLDGKKDARQVTSNSLSGTQEDGLDDPRLEKLWHKAKTSGKFSGEELDKLWREFLH 178
+ +++ + Q++ + + E++W + + + + +K+WR+
Sbjct: 356 REQEEKIREQEEKMWRQEEKIREQDEKIQEQE-EEMWRQEEKIREQEEKRQEKMWRQEKK 414
Query: 179 HKEKVHEYNVLLETLSRTEEIHENVISPSDLSDIKGSVLHSRHTELKEKLRSINQGLDRL 238
+E+ + E + R EE + + K + + E +EK++ + + R
Sbjct: 415 MREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQ 474
Query: 239 RRVSHQGYSTEAEFEEPRVIDLWDLAQSANLTDKELEAFREELKHFEAKIEKHNHYQKQL 298
+ E + + ++ L Q + ++E + +R+E K +E + EK ++++
Sbjct: 475 EEKIQE--QEEKTWRQEKL-----LKQEEKIWEQEEKMWRQEEKMWEQE-EKMQEQEEKM 526
Query: 299 EIAHEKLRHAESVGDGERVSRSREKHALLEGRTKEL 334
+ EK+R E R+ + EK E R +EL
Sbjct: 527 QRQEEKMREQE-----VRLWQQEEKMQEQEVRLQEL 557
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 41.6 bits (96), Expect = 0.001
Identities = 50/276 (18%), Positives = 122/276 (44%), Gaps = 18/276 (6%)
Query: 61 QLWEKAQRLHLPPVRLAELHADLKIQERDELAWKKLKLDGLDEDG--EKEARLIRNLNVI 118
++W + +++ ++ E +LKI+E++E W++ + E+ E+E ++ R I
Sbjct: 298 KMWRQEEKIQEQEEKMCE--QELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKI 355
Query: 119 LAKYGLDGKKDARQVTSNSLSGTQEDGLDDPRLEKLWHKAKTSGKFSGEELDKLWREFLH 178
+ +++ + Q++ + + E++W + + + + +K+WR+
Sbjct: 356 REQEEKIREQEEKMWRQEEKIREQDEKIQEQE-EEMWRQEEKIREQEEKRQEKMWRQEKK 414
Query: 179 HKEKVHEYNVLLETLSRTEEIHENVISPSDLSDIKGSVLHSRHTELKEKLRSINQGLDRL 238
+E+ + E + R EE + + K + + E +EK++ + + R
Sbjct: 415 MREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQ 474
Query: 239 RRVSHQGYSTEAEFEEPRVIDLWDLAQSANLTDKELEAFREELKHFEAKIEKHNHYQKQL 298
+ E + + ++ L Q + ++E + +R+E K +E + EK ++++
Sbjct: 475 EEKIQE--QEEKTWRQEKL-----LKQEEKIWEQEEKMWRQEEKMWEQE-EKMQEQEEKM 526
Query: 299 EIAHEKLRHAESVGDGERVSRSREKHALLEGRTKEL 334
+ EK+R E R+ + EK E R +EL
Sbjct: 527 QRQEEKMREQE-----VRLWQQEEKMQEQEVRLQEL 557
>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
Length = 3907
Score = 40.8 bits (94), Expect = 0.002
Identities = 64/290 (22%), Positives = 132/290 (45%), Gaps = 19/290 (6%)
Query: 36 SREKNQPKPSPKRESGE--EFRMEKLNQL-------WEKAQ-RLHLPPVRLA-ELHADLK 84
S+E+ Q + E E EFR+ +L Q ++K + R H V EL +++
Sbjct: 2131 SKEQLQRDIQERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKHFGAVEAKPELSLEVQ 2190
Query: 85 IQ-ERDELAWKKLKLDGLDEDGEKEARLIRNLNVILAKYGLDGKKDARQVTSNSLSGTQE 143
+Q ERD + K+ ++ L+E E+ + N N + + + + ++ T+ QE
Sbjct: 2191 LQAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQE 2250
Query: 144 DGLDDPRLEKLWHKAKTSGKFSGEELDKLWREFLH-HKEKVHEYNVLLETLSRTEEIHEN 202
+ L +EKL K S S ++ L+ +F +EK E + L E +++ ++
Sbjct: 2251 NKLFKDDMEKLGLAIKESDAMSTQDQHVLFGKFAQIIQEKEVEIDQLNEQVTKLQQ-QLK 2309
Query: 203 VISPSDLSDIKGSVLHSRHTELKEKLRSINQGLDRLRRVSHQGYSTEAEFEEPRVIDLWD 262
+ + + + + K ++ T++ E L S + + R R + + E E +L +
Sbjct: 2310 ITTDNKVIEEKNELIRDLETQI-ECLMSDQECVKRNREEEIEQLN---EVIEKLQQELAN 2365
Query: 263 LAQSANLTDKELEAFREELKH-FEAKIEKHNHYQKQLEIAHEKLRHAESV 311
+ Q ++ L + LKH + I + ++Q+E A+E++ ++V
Sbjct: 2366 IGQKTSMNAHSLSEEADSLKHQLDVVIAEKLALEQQVETANEEMTFMKNV 2415
>gi|56961680 coiled-coil domain containing 147 [Homo sapiens]
Length = 872
Score = 40.4 bits (93), Expect = 0.002
Identities = 68/324 (20%), Positives = 138/324 (42%), Gaps = 44/324 (13%)
Query: 38 EKNQPKP---SPKRESGEEFRME--KLNQLWEKA-QRLHLPPVRLAELHAD---LKIQ-- 86
++NQ K K E + R++ KLN++ E+ ++LH + AE+ LK Q
Sbjct: 300 QENQQKALELKAKEEEVHQMRLDIGKLNKIREQIHKKLHHTEDQKAEVEQHKETLKNQIV 359
Query: 87 --ERD-ELAWKKLKLDGLDEDGEKEARLIRNLNVILAKYGLDGKKDA---RQVTSNSLSG 140
ER+ E + K+ +LD D R I N N++ A + D + +L G
Sbjct: 360 GLEREVEASKKQAELDRKAMDELLRERDILNKNMLKAVNATQKQTDLVKLHEQAKRNLEG 419
Query: 141 TQEDGLDDPRLEK--LWHKAKTSGKFSGEELDKLWREFLHHKE-KVHEYNV------LLE 191
++ D+ + ++ ++H K ++ + D + ++ ++ KV E + + E
Sbjct: 420 EIQNYKDEAQKQRKIIFHLEKERDRYINQASDLTQKVLMNMEDIKVRETQIFDYRKKIAE 479
Query: 192 T---LSRTEEIHENVISPSDLSDIKGSVLHSRHTELKEKLRSINQGLDRLRR--VSHQGY 246
+ L + + ++E V S +L T++K KL+ + +D L+ + +
Sbjct: 480 SEIKLKQQQNLYEAVRSDRNLYSKNLVEAQDEITDMKRKLKIMIHQVDELKEDISAKESA 539
Query: 247 STEAEFEEPRVIDLWDLAQSANLTDKELEAFREELKHFEAKIEKHNHYQKQLEIAHEKLR 306
+ E+ R+ +KE E + EL+ + + H+ ++ E KL
Sbjct: 540 LVKLHLEQQRI-------------EKEKETLKAELQKLRQQALETKHFIEKQEAEERKLL 586
Query: 307 HAESVGDGERVSRSREKHALLEGR 330
+ DGER+ + +E ++ R
Sbjct: 587 RIIAEADGERLRQKKELDQVISER 610
>gi|42740899 CTAGE family, member 5 isoform 3 [Homo sapiens]
Length = 761
Score = 40.0 bits (92), Expect = 0.003
Identities = 41/180 (22%), Positives = 79/180 (43%), Gaps = 16/180 (8%)
Query: 132 QVTSNSLSGTQEDGLDDPRLEKLWHKAKTSGKFSGEELDKLWREFLHHKEKVHEYNVLLE 191
++ S S +G D L+KL H AK + E E+ Y L E
Sbjct: 294 EMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTLE-----------GERNQIYIQLSE 342
Query: 192 TLSRTEEIHENVIS-PSDLSDIKGSVLH--SRHTELKEKLRSINQGLDRLRRVSHQGYST 248
EE+ E++ + ++ + ++ H + + +L++KL+ + + H+ +
Sbjct: 343 VDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTV 402
Query: 249 EAEFEEPRVIDLWDLAQSANLTDKELEAFREELKHFEAKIEKHNH-YQKQLEIAHEKLRH 307
E + + L + + + +ELE +R+ K E ++E+ H YQ Q+ I+HEK H
Sbjct: 403 EENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSYQGQI-ISHEKKAH 461
>gi|42740897 CTAGE family, member 5 isoform 1 [Homo sapiens]
Length = 804
Score = 40.0 bits (92), Expect = 0.003
Identities = 41/180 (22%), Positives = 79/180 (43%), Gaps = 16/180 (8%)
Query: 132 QVTSNSLSGTQEDGLDDPRLEKLWHKAKTSGKFSGEELDKLWREFLHHKEKVHEYNVLLE 191
++ S S +G D L+KL H AK + E E+ Y L E
Sbjct: 294 EMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTLE-----------GERNQIYIQLSE 342
Query: 192 TLSRTEEIHENVIS-PSDLSDIKGSVLH--SRHTELKEKLRSINQGLDRLRRVSHQGYST 248
EE+ E++ + ++ + ++ H + + +L++KL+ + + H+ +
Sbjct: 343 VDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTV 402
Query: 249 EAEFEEPRVIDLWDLAQSANLTDKELEAFREELKHFEAKIEKHNH-YQKQLEIAHEKLRH 307
E + + L + + + +ELE +R+ K E ++E+ H YQ Q+ I+HEK H
Sbjct: 403 EENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSYQGQI-ISHEKKAH 461
>gi|42740901 CTAGE family, member 5 isoform 4 [Homo sapiens]
Length = 775
Score = 40.0 bits (92), Expect = 0.003
Identities = 41/180 (22%), Positives = 79/180 (43%), Gaps = 16/180 (8%)
Query: 132 QVTSNSLSGTQEDGLDDPRLEKLWHKAKTSGKFSGEELDKLWREFLHHKEKVHEYNVLLE 191
++ S S +G D L+KL H AK + E E+ Y L E
Sbjct: 265 EMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTLE-----------GERNQIYIQLSE 313
Query: 192 TLSRTEEIHENVIS-PSDLSDIKGSVLH--SRHTELKEKLRSINQGLDRLRRVSHQGYST 248
EE+ E++ + ++ + ++ H + + +L++KL+ + + H+ +
Sbjct: 314 VDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTV 373
Query: 249 EAEFEEPRVIDLWDLAQSANLTDKELEAFREELKHFEAKIEKHNH-YQKQLEIAHEKLRH 307
E + + L + + + +ELE +R+ K E ++E+ H YQ Q+ I+HEK H
Sbjct: 374 EENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSYQGQI-ISHEKKAH 432
>gi|42740905 CTAGE family, member 5 isoform 2 [Homo sapiens]
Length = 792
Score = 40.0 bits (92), Expect = 0.003
Identities = 41/180 (22%), Positives = 79/180 (43%), Gaps = 16/180 (8%)
Query: 132 QVTSNSLSGTQEDGLDDPRLEKLWHKAKTSGKFSGEELDKLWREFLHHKEKVHEYNVLLE 191
++ S S +G D L+KL H AK + E E+ Y L E
Sbjct: 282 EMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTLE-----------GERNQIYIQLSE 330
Query: 192 TLSRTEEIHENVIS-PSDLSDIKGSVLH--SRHTELKEKLRSINQGLDRLRRVSHQGYST 248
EE+ E++ + ++ + ++ H + + +L++KL+ + + H+ +
Sbjct: 331 VDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTV 390
Query: 249 EAEFEEPRVIDLWDLAQSANLTDKELEAFREELKHFEAKIEKHNH-YQKQLEIAHEKLRH 307
E + + L + + + +ELE +R+ K E ++E+ H YQ Q+ I+HEK H
Sbjct: 391 EENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSYQGQI-ISHEKKAH 449
>gi|81295809 pericentrin [Homo sapiens]
Length = 3336
Score = 39.7 bits (91), Expect = 0.004
Identities = 73/329 (22%), Positives = 134/329 (40%), Gaps = 54/329 (16%)
Query: 56 MEKLNQLWEKAQRLHLPPVRLAELHA-------DLKIQERDELAWKKLKLDGLDEDGEKE 108
++ L + WE + L L +R EL A DL+ Q + ELA ++ +L+ + +D +
Sbjct: 343 VKTLKEDWESEKDLCLENLR-KELSAKHQSEMEDLQNQFQKELAEQRAELEKIFQDKNQA 401
Query: 109 ARLIRNLNV------------ILAKYG---------LDGKKDARQVTSNSLSGTQED--G 145
R +RNL + +++G + +Q+ +L + ED
Sbjct: 402 ERALRNLESHHQAAIEKLREDLQSEHGRCLEDLEFKFKESEKEKQLELENLQASYEDLKA 461
Query: 146 LDDPRLEKLWHKAKTSGKFSGEELDKLWREFLHHKEKVHEYNVLLETLSRTEEI-HENVI 204
+ +LW + S + S +EL +L + L +V + LE L + E+ HE+ +
Sbjct: 462 QSQEEIRRLWSQL-DSARTSRQELSELHEQLLARTSRVED----LEQLKQREKTQHESEL 516
Query: 205 SPSDLSDIKGSVLHSRHTELKEKLRSINQGL-----DRLRRVSHQGYSTEAEFEEPRVID 259
L L +E L + Q L D L G S E+P
Sbjct: 517 --EQLRIYFEKKLRDAEKTYQEDLTLLQQRLQGAREDALLDSVEVGLSCVGLEEKP---- 570
Query: 260 LWDLAQSANLTDKELEAFREELKHFEAKIEKHNHYQKQLEIAHEKLRHAESVGDGERVSR 319
+ + ++ + E E +E L F+A++E+ + +Q + + ++H V D V
Sbjct: 571 --EKGRKDHVDELEPERHKESLPRFQAELEESHRHQLEALESPLCIQHEGHVSDRCCVET 628
Query: 320 SREKHAL----LEGRTKELGYTVKKHLQD 344
S H EG ++EL + + +QD
Sbjct: 629 SALGHEWRLEPSEGHSQELPWVHLQGVQD 657
>gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]
Length = 1417
Score = 39.7 bits (91), Expect = 0.004
Identities = 78/342 (22%), Positives = 143/342 (41%), Gaps = 56/342 (16%)
Query: 38 EKNQPKPSPKRESGEEFRMEKLNQLWEK----AQRLHLPPVRLAELHA---DLKI---QE 87
EK K + + E EKL ++ EK A L ++ EL +KI Q
Sbjct: 936 EKQVSKLEQELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQY 995
Query: 88 RDELAWKKLKLDGLDEDGEKEARLIRNLNVILAKYGLDGKKDARQVTSNSLSGTQEDGLD 147
++EL+ + ++ L DGE +A + L++I LD K + +N++
Sbjct: 996 KEELSKMEKEIMHLKRDGENKAMHLSQLDMI-----LDQTKTELEKKTNAVK-------- 1042
Query: 148 DPRLEKLWHKAKTSGKFSGEELDKLWREFLHHKEKVHEYNVLLETLSRTEEIHENVISPS 207
LEKL H +T E + L + + E + + L TL + +E+ + V+ +
Sbjct: 1043 --ELEKLQHSTET------ELTEALQKREVLETELQNAHGELKSTLRQLQELRD-VLQKA 1093
Query: 208 DLS------DIKGSVLHSRHTEL-----KEKLRSINQGLD----RLRRVSHQGYSTEAEF 252
LS IK R ++ K++L ++Q L L++ + Q +
Sbjct: 1094 QLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQVTHLDMTI 1153
Query: 253 EEPRVIDLWDLAQSANLTDKELEAFREELKHFEAKIEKHNHYQKQLEIAHEKLRHAESV- 311
E R ++ Q + LE ELK +IE N +L+ A E+LR E +
Sbjct: 1154 REHR----GEMEQKIIKLEGTLEKSELELKECNKQIESLN---DKLQNAKEQLREKEFIM 1206
Query: 312 -GDGERVSRSREKHALLEGRTKELGYTVKKHLQDLSGRISRA 352
+ + +S+ +++ + R KE+ +K+ Q ++ + A
Sbjct: 1207 LQNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQYKEA 1248
>gi|23097308 spectrin repeat containing, nuclear envelope 1 isoform 2
[Homo sapiens]
Length = 8749
Score = 38.9 bits (89), Expect = 0.007
Identities = 57/274 (20%), Positives = 112/274 (40%), Gaps = 46/274 (16%)
Query: 74 VRLAELHADLKIQERDELAWKKLKLDGL--DEDGEKEARLIRNLNVILAKYGLDGKKDAR 131
++LAE+ DLKI+++ + K+++ E + +L ++L IL K +
Sbjct: 5327 LQLAEVALDLKIRDQIQDKIKEVEQSKATSQELSRQIQKLAKDLTTILTKLKAKTDNVVQ 5386
Query: 132 QVTSNSLSGTQEDGLDDPRLEKLWHKAKTSGKFSGEELDKLWREFLHHKEKVHEYNVLLE 191
T + G + DG + +E LD ++FL ++ + L +
Sbjct: 5387 AKTDQKVLGEELDGCNSKLME----------------LDAAVQKFLEQNGQLGK--PLAK 5428
Query: 192 TLSRTEEIHENVISPSDLSDIKGSVLHSRHTELKEKLRSINQGLDRLRRVSHQGYSTEAE 251
+ + E+H+ I ++ K + S E E L I + +++ + ++H +
Sbjct: 5429 KIGKLTELHQQTIRQAENRLSKLNQAASHLEEYNEMLELILKWIEKAKVLAHGTIA---- 5484
Query: 252 FEEPRVIDLWDLAQSANLTDKELEAFREELKHFEAKIEKHNHYQKQLEIAHEKLRHAESV 311
W+ A RE+ + +E+ +LE EKL++ SV
Sbjct: 5485 ---------WNSASQ----------LREQYILHQTLLEESKEIDSELEAMTEKLQYLTSV 5525
Query: 312 GDGERVSRSREKHALLEGRTKELGYTVKKHLQDL 345
E++S ++ A L T+EL +K LQ+L
Sbjct: 5526 YCTEKMS---QQVAELGRETEELRQMIKIRLQNL 5556
Score = 33.9 bits (76), Expect = 0.23
Identities = 52/222 (23%), Positives = 92/222 (41%), Gaps = 48/222 (21%)
Query: 167 EELDKLWREFLHHKEKVHE------------------YNVLLETLSRTE----EIHENVI 204
EE +LW++FL + + Y V E L + E ++HE +
Sbjct: 7924 EETWRLWQKFLDDYSRFEDWLKSSERTAAFPSSSGVIYTVAKEELKKFEAFQRQVHECLT 7983
Query: 205 SPSDLSDIKGSVLHSRHTE----LKEKLRSINQGLDRL--------RRVSHQGYSTEAEF 252
++ + T+ LK+ + NQ D L RR+ H E EF
Sbjct: 7984 QLELINKQYRRLARENRTDSACSLKQMVHEGNQRWDNLQKRVTSILRRLKHFIGQRE-EF 8042
Query: 253 EEPR-VIDLWDLAQSANLTDKELEAFREELKHFEAKIEKHNHYQKQLEIAHEKLRHAESV 311
E R I +W LT+ +E F E +AKI++ +Q+++ + H K+ + +
Sbjct: 8043 ETARDSILVWLTEMDLQLTN--IEHFSE--CDVQAKIKQLKAFQQEISLNHNKIE--QII 8096
Query: 312 GDGERVSRSRE--KHALLEGRTKELGYTVKKHLQDLSGRISR 351
GE++ E A++E EL +++ Q++ GR+ R
Sbjct: 8097 AQGEQLIEKSEPLDAAIIEEELDEL----RRYCQEVFGRVER 8134
Score = 32.3 bits (72), Expect = 0.67
Identities = 36/190 (18%), Positives = 82/190 (43%), Gaps = 27/190 (14%)
Query: 152 EKLWHKAKTSGKFSGEELDKLWREFLHHKEKVHEYNVLLET-LSRTEEIHENVISPSDLS 210
E+L H+ + GE L++ W F +++ E+ +E+ +S+ +I +
Sbjct: 7691 EELCHQLSLRRQQIGERLNE-WAVFSEKNKELCEWLTQMESKVSQNGDILIEEMIEKLKK 7749
Query: 211 DIKGSVLHSRHTELKEKLRSINQGLDRLRRVSHQGYSTEAEFEEPRVIDLW--------- 261
D + + ++ +++ + Q +RL + SH+ ++E E++ +V D W
Sbjct: 7750 DYQEEIAIAQENKIQ-----LQQMGERLAKASHESKASEIEYKLGKVNDRWQHLLDLIAA 7804
Query: 262 ------DLAQSANLTDKELEAFREELKHFEAKIEKHNHYQKQLEIAHEKLRHAESVGDGE 315
+ + DK + + R L H E+++ K Y E+++ + + +
Sbjct: 7805 RVKKLKETLVAVQQLDKNMSSLRTWLAHIESELAKPIVYD---SCNSEEIQ--RKLNEQQ 7859
Query: 316 RVSRSREKHA 325
+ R EKH+
Sbjct: 7860 ELQRDIEKHS 7869
>gi|154277116 spectrin repeat containing, nuclear envelope 1 isoform 1
[Homo sapiens]
Length = 8797
Score = 38.9 bits (89), Expect = 0.007
Identities = 57/274 (20%), Positives = 112/274 (40%), Gaps = 46/274 (16%)
Query: 74 VRLAELHADLKIQERDELAWKKLKLDGL--DEDGEKEARLIRNLNVILAKYGLDGKKDAR 131
++LAE+ DLKI+++ + K+++ E + +L ++L IL K +
Sbjct: 5398 LQLAEVALDLKIRDQIQDKIKEVEQSKATSQELSRQIQKLAKDLTTILTKLKAKTDNVVQ 5457
Query: 132 QVTSNSLSGTQEDGLDDPRLEKLWHKAKTSGKFSGEELDKLWREFLHHKEKVHEYNVLLE 191
T + G + DG + +E LD ++FL ++ + L +
Sbjct: 5458 AKTDQKVLGEELDGCNSKLME----------------LDAAVQKFLEQNGQLGK--PLAK 5499
Query: 192 TLSRTEEIHENVISPSDLSDIKGSVLHSRHTELKEKLRSINQGLDRLRRVSHQGYSTEAE 251
+ + E+H+ I ++ K + S E E L I + +++ + ++H +
Sbjct: 5500 KIGKLTELHQQTIRQAENRLSKLNQAASHLEEYNEMLELILKWIEKAKVLAHGTIA---- 5555
Query: 252 FEEPRVIDLWDLAQSANLTDKELEAFREELKHFEAKIEKHNHYQKQLEIAHEKLRHAESV 311
W+ A RE+ + +E+ +LE EKL++ SV
Sbjct: 5556 ---------WNSASQ----------LREQYILHQTLLEESKEIDSELEAMTEKLQYLTSV 5596
Query: 312 GDGERVSRSREKHALLEGRTKELGYTVKKHLQDL 345
E++S ++ A L T+EL +K LQ+L
Sbjct: 5597 YCTEKMS---QQVAELGRETEELRQMIKIRLQNL 5627
Score = 33.9 bits (76), Expect = 0.23
Identities = 52/222 (23%), Positives = 92/222 (41%), Gaps = 48/222 (21%)
Query: 167 EELDKLWREFLHHKEKVHE------------------YNVLLETLSRTE----EIHENVI 204
EE +LW++FL + + Y V E L + E ++HE +
Sbjct: 7995 EETWRLWQKFLDDYSRFEDWLKSSERTAAFPSSSGVIYTVAKEELKKFEAFQRQVHECLT 8054
Query: 205 SPSDLSDIKGSVLHSRHTE----LKEKLRSINQGLDRL--------RRVSHQGYSTEAEF 252
++ + T+ LK+ + NQ D L RR+ H E EF
Sbjct: 8055 QLELINKQYRRLARENRTDSACSLKQMVHEGNQRWDNLQKRVTSILRRLKHFIGQRE-EF 8113
Query: 253 EEPR-VIDLWDLAQSANLTDKELEAFREELKHFEAKIEKHNHYQKQLEIAHEKLRHAESV 311
E R I +W LT+ +E F E +AKI++ +Q+++ + H K+ + +
Sbjct: 8114 ETARDSILVWLTEMDLQLTN--IEHFSE--CDVQAKIKQLKAFQQEISLNHNKIE--QII 8167
Query: 312 GDGERVSRSRE--KHALLEGRTKELGYTVKKHLQDLSGRISR 351
GE++ E A++E EL +++ Q++ GR+ R
Sbjct: 8168 AQGEQLIEKSEPLDAAIIEEELDEL----RRYCQEVFGRVER 8205
Score = 32.3 bits (72), Expect = 0.67
Identities = 36/190 (18%), Positives = 82/190 (43%), Gaps = 27/190 (14%)
Query: 152 EKLWHKAKTSGKFSGEELDKLWREFLHHKEKVHEYNVLLET-LSRTEEIHENVISPSDLS 210
E+L H+ + GE L++ W F +++ E+ +E+ +S+ +I +
Sbjct: 7762 EELCHQLSLRRQQIGERLNE-WAVFSEKNKELCEWLTQMESKVSQNGDILIEEMIEKLKK 7820
Query: 211 DIKGSVLHSRHTELKEKLRSINQGLDRLRRVSHQGYSTEAEFEEPRVIDLW--------- 261
D + + ++ +++ + Q +RL + SH+ ++E E++ +V D W
Sbjct: 7821 DYQEEIAIAQENKIQ-----LQQMGERLAKASHESKASEIEYKLGKVNDRWQHLLDLIAA 7875
Query: 262 ------DLAQSANLTDKELEAFREELKHFEAKIEKHNHYQKQLEIAHEKLRHAESVGDGE 315
+ + DK + + R L H E+++ K Y E+++ + + +
Sbjct: 7876 RVKKLKETLVAVQQLDKNMSSLRTWLAHIESELAKPIVYD---SCNSEEIQ--RKLNEQQ 7930
Query: 316 RVSRSREKHA 325
+ R EKH+
Sbjct: 7931 ELQRDIEKHS 7940
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 38.5 bits (88), Expect = 0.009
Identities = 53/302 (17%), Positives = 119/302 (39%), Gaps = 45/302 (14%)
Query: 38 EKNQPKPSPKRESGEEFRMEKLNQLWEKAQRLHLPPVRLAE-----------LHADLKIQ 86
EK Q + RE E+ R ++ +WEK +++ + E +H KI+
Sbjct: 302 EKIQEQEEKIREQEEKMRRQE-EMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIR 360
Query: 87 ERDELAWKKLKLDGLDEDGEKEARLIRNLNVILAKYGLDGKKDARQVTSNSLSGTQEDGL 146
E++E ++ K+ ++ E+EA++ R I + +++ G QE
Sbjct: 361 EQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQE--- 417
Query: 147 DDPRLEKLWHKAKTSGKFSGEELDKLWREFLHHKEKVHEYNVLLETLSRTEEIHENVISP 206
EK+W + EE+ + + +EK+ E + E E +
Sbjct: 418 -----EKMWEQE--------EEMQEQEEKMRRQEEKIREQE------KKIREQEEKIREQ 458
Query: 207 SDLSDIKGSVLHSRHTELKEKLRSINQGLDRLRRVSHQGYSTEAEFEEPRVIDLWDLAQS 266
++ + + + ++ E+ + + +++RR + E + E Q
Sbjct: 459 EEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIRE----------QE 508
Query: 267 ANLTDKELEAFREELKHFEAKIEKHNHYQKQLEIAHEKLRHAESVGDGERVSRSREKHAL 326
+ ++E +E K +E + EK +++++ EK+R E + V +++ +
Sbjct: 509 EKIREQEEMMQEQEEKMWEQE-EKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKM 567
Query: 327 LE 328
E
Sbjct: 568 QE 569
>gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]
Length = 1979
Score = 38.1 bits (87), Expect = 0.012
Identities = 61/266 (22%), Positives = 106/266 (39%), Gaps = 34/266 (12%)
Query: 78 ELHADLKIQERDELAWKKLKLDGLDEDGEKEARLIRNLNVILAKYGLDGKKDARQVTSNS 137
E + I E++ L + +LD +++ K LI++ + +Q +S
Sbjct: 480 EQELNQSISEKETLIAEIEELDRQNQEATKHMILIKD------------QLSKQQNEGDS 527
Query: 138 LSGTQEDGLDDPRLEKLWHKAKTSGKFSGEELDKLWREFLHHKEKVHEYNVLLETLSRT- 196
+ + L+D + K H+ + +ELD KEK+ + V L L T
Sbjct: 528 IISKLKQDLNDEK--KRVHQLEDDKMDITKELDV-------QKEKLIQSEVALNDLHLTK 578
Query: 197 ---EEIHENVISPSDLSDIKGSVLHSRHTELKEKLRSINQGLDRLRRVSHQGYSTEAEFE 253
E+ EN++ + S + + ELKE +R + L R+R Q + ++
Sbjct: 579 QKLEDKVENLVDQLNKSQESNVSIQKENLELKEHIRQNEEELSRIRNELMQSLNQDSNSN 638
Query: 254 EPRVIDLWDLAQSANLTD--KELEAFREELKH--FEAKIEKHNHYQKQLEIAHEKLRHAE 309
+ A+ NL ELE E LK F+ K+E ++L +A E +RH
Sbjct: 639 FKDTLLKEREAEVRNLKQNLSELEQLNENLKKVAFDVKME-----NEKLVLACEDVRHQL 693
Query: 310 SVGDGERVSRSREKHALLEGRTKELG 335
S EK+ ++E E G
Sbjct: 694 EECLAGNNQLSLEKNTIVETLKMEKG 719
Score = 35.0 bits (79), Expect = 0.10
Identities = 60/254 (23%), Positives = 102/254 (40%), Gaps = 56/254 (22%)
Query: 47 KRESGEEFRMEKLNQLWEKAQRLHLPPVRLAELHADLKIQERD-ELAWKKLKLDGLDEDG 105
KR E + EK + A+ L+ ++L H Q++D E+A K ++ +D D
Sbjct: 730 KRLLEEANKYEKTIEELSNARNLNTSALQLEHEHLIKLNQKKDMEIAELKKNIEQMDTD- 788
Query: 106 EKEARLIRNLNVILAKYGLDGKKDARQVTSNSLSGTQEDGLDDPRLEKLWHKAKTSGKFS 165
K+ + V S+SL + +L +L +K + +
Sbjct: 789 ---------------------HKETKDVLSSSLE-------EQKQLTQLINKKEIFIEKL 820
Query: 166 GEELDKLWREFLHHKEKVHEYNVLLETLSRTEEIHENVISPSDLSDIKGSVLHSRHTELK 225
E KL +E++ +Y+ L R EI I D S GS +K
Sbjct: 821 KERSSKL-------QEELDKYSQAL----RKNEILRQTIEEKDRS--LGS--------MK 859
Query: 226 EKLRSINQGLDRLRRVSHQGYSTEAEFEEPRVID-LWDLAQSANLTDKELEAFREELKHF 284
E+ + + L+RLR + S A +P+ +D + +LA + + E EE+KH
Sbjct: 860 EENNHLQEELERLR----EEQSRTAPVADPKTLDSVTELASEVSQLNTIKEHLEEEIKHH 915
Query: 285 EAKIEKHNHYQKQL 298
+ IE N + QL
Sbjct: 916 QKIIEDQNQSKMQL 929
Score = 29.3 bits (64), Expect = 5.7
Identities = 37/190 (19%), Positives = 78/190 (41%), Gaps = 39/190 (20%)
Query: 181 EKVHEYNVLLETLSRTEEI--------HENVISPSDLSDIKGSVLHSR----HTELKEKL 228
E+ ++Y +E LS + HE++I + D++ + L T+ KE
Sbjct: 734 EEANKYEKTIEELSNARNLNTSALQLEHEHLIKLNQKKDMEIAELKKNIEQMDTDHKETK 793
Query: 229 RSINQGLDRLRRVSHQGYSTEAEFEEPRVIDLWDLAQSANLTDKELEAFREELKHFE--- 285
++ L+ ++++ E E+ L + ++ +EL+ + + L+ E
Sbjct: 794 DVLSSSLEEQKQLTQLINKKEIFIEK--------LKERSSKLQEELDKYSQALRKNEILR 845
Query: 286 -----------AKIEKHNHYQKQLEIAHEKLRHAESVGDGERVSRSREKHALLEGRTKEL 334
+ E++NH Q++LE E+ V D + + E L +L
Sbjct: 846 QTIEEKDRSLGSMKEENNHLQEELERLREEQSRTAPVADPKTLDSVTE----LASEVSQL 901
Query: 335 GYTVKKHLQD 344
T+K+HL++
Sbjct: 902 N-TIKEHLEE 910
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 37.7 bits (86), Expect = 0.016
Identities = 53/253 (20%), Positives = 106/253 (41%), Gaps = 15/253 (5%)
Query: 88 RDELAWKKLKLDGLDEDGEKEARLIRNLNVILAKYGLDGKKDARQVTSNSLSGTQEDGLD 147
+ EL + +D + + E+E+ +++ L + Q+ S G QE +
Sbjct: 227 KKELVQVQTLMDNMTLERERESEKLKDECKKLQSQYASSEATISQLRSELAKGPQEVAVY 286
Query: 148 DPRLEKLW---HKAKTSGKFSGEELDKLWREFLHHKEKVHEYNVLLETLSRTEEIHENVI 204
L+KL ++ + E L K +++ +EK +E +V + + T +H+ +
Sbjct: 287 VQELQKLKSSVNELTQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQAT--LHQKDL 344
Query: 205 SPSDLSD---IKGSVLHSRHTELKEKLRSINQGLDRLRRVSHQGYSTEAEFEEPRVIDLW 261
L + LH H EL EK + + + L V + +AEF++ +
Sbjct: 345 DCQQLQSRLSASETSLHRIHVELSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQ-QRE 403
Query: 262 DLAQSANLTDKELEAFREELKHFEAKI-EKHNHYQKQLEIAHEKLRHAESVGDGERVSRS 320
+ Q E+ +L E ++ E H ++Q +++ EKL E ++V+
Sbjct: 404 EKEQHGLQLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDKE-----QQVADL 458
Query: 321 REKHALLEGRTKE 333
+ K + LE + KE
Sbjct: 459 QLKLSRLEEQLKE 471
Score = 36.6 bits (83), Expect = 0.035
Identities = 50/224 (22%), Positives = 92/224 (41%), Gaps = 43/224 (19%)
Query: 128 KDARQVTSNSLSGTQEDGLDDPRLEKLWHKAKTSGKFSGEELDKLWREFLHHKEKVHEYN 187
KD S+SL ++ + + K GK + +L+K +E H + E
Sbjct: 859 KDKLSKVSDSLKNSKSE----------FEKENQKGKAAILDLEKTCKELKHQLQVQME-- 906
Query: 188 VLLETLSRTEEIHENVISPSDLSDIKGSVLHSRHTELKEKLRSINQGLDRLRRVSHQGYS 247
TL +E+ +++ + S +LK +L S+ + L + + Q
Sbjct: 907 ---NTLKEQKELKKSLEKEKEASH-----------QLKLELNSMQEQLIQAQNTLKQNEK 952
Query: 248 TEAEFEEPRVIDLWDLAQSANLTDKELEAFREELK-HFEAKIEKHNHYQKQLEIAHEKLR 306
E + + ++ +L QS+ K++EA + ELK K E N Q+QL A ++L
Sbjct: 953 EEQQLQG----NINELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQEL- 1007
Query: 307 HAESVGDGERVSRSREKHALLEGRTKELGYTVKKHLQDLSGRIS 350
+ +EK ++L+ ++ T K+ D GR S
Sbjct: 1008 -----------AAEKEKISVLQNNYEKSQETFKQLQSDFYGRES 1040
Score = 28.5 bits (62), Expect = 9.7
Identities = 71/317 (22%), Positives = 128/317 (40%), Gaps = 53/317 (16%)
Query: 34 KYSREKNQPKPSPKRESGEEFRMEKLNQLWEKAQRLHLPPV-RLAELHADLKIQERDELA 92
K SR + Q K + + +++K Q ++ Q L +L E DL+
Sbjct: 461 KLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLE-------- 512
Query: 93 WKKLKLDGLDEDGEKEARLIRNLNVILAKYGLDG---KKDARQVTSNSLSGTQEDGLDDP 149
L + G+K+ + I+NL +L K + +K+ + + +G E +
Sbjct: 513 ------QVLRQIGDKDQK-IQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAV--- 562
Query: 150 RLEKLWHKAKTSGKFSGEELDKLWREFLHHKEKVHE-YNVLLETLSRTEEIHENVISPSD 208
L +L K T + + +KL + HK+ ++ + E + + V+S
Sbjct: 563 -LNQLQEKNHTLQEQVTQLTEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLS--- 618
Query: 209 LSDIKGSVLHSRHTELKEKLRSINQGLDRLRRVSHQGYSTEAEFEEPRVIDLW---DLAQ 265
+ + L+S+ E KEK+ ++ +++ + S EA R DL D AQ
Sbjct: 619 -LETSVNELNSQLNESKEKVSQLDI---QIKAKTELLLSAEAAKTAQRA-DLQNHLDTAQ 673
Query: 266 SANLTDK--ELEAFREELKHFEAKIEKHNHYQKQLEIAHEKLRHAESVGDGERVSRSREK 323
+A L DK EL +L AK++ + QLE + +EK
Sbjct: 674 NA-LQDKQQELNKITTQLDQVTAKLQDKQEHCSQLE---------------SHLKEYKEK 717
Query: 324 HALLEGRTKELGYTVKK 340
+ LE +T+EL +KK
Sbjct: 718 YLSLEQKTEELEGQIKK 734
>gi|29171753 PTPRF interacting protein alpha 1 isoform a [Homo
sapiens]
Length = 1185
Score = 37.4 bits (85), Expect = 0.021
Identities = 67/285 (23%), Positives = 125/285 (43%), Gaps = 46/285 (16%)
Query: 101 LDEDGEKEARL-IRNLNVILAKYGLDGKKDARQVTSNSLSGTQEDGLDDPRLEKLWHKAK 159
LDE + R+ + +++ + G K+ N+ T DG+ D E+ +
Sbjct: 174 LDEKVRERLRVALERCSLLEEELGATHKELMILKEQNNQKKTLTDGVLDINHEQE-NTPS 232
Query: 160 TSGKFSGEELDKLWREFLHHKEKVHEYNVLLETLSRTEEIHENVISPSDLSDIKGSVLHS 219
TSGK S + L H+E + + L E +S+ S + + S L S
Sbjct: 233 TSGKRSSDGS-------LSHEEDLAKVIELQEIISKQSR------EQSQMKERLAS-LSS 278
Query: 220 RHTELKEKLRSINQGL-------DRLRRVSHQGYSTEAEFEEPRVIDLWDLAQSA----- 267
TEL+E L + + L +L+R + + + + EE R+ L +A
Sbjct: 279 HVTELEEDLDTARKDLIKSEEMNTKLQRDVREAMAQKEDMEE-RITTLEKRYLAAQREAT 337
Query: 268 ---NLTDK-ELEAFREELKHFEAKIEKHNHYQKQLEIAHEKL----RHAESVGDGER--- 316
+L DK E E ++ H + + +K+ Q++LE+A +KL R AE++ + E
Sbjct: 338 SVHDLNDKLENEIANKDSMHRQTE-DKNRQLQERLELAEQKLQQTLRKAETLPEVEAELA 396
Query: 317 -----VSRSREKHALLEGRTKELGYTVKKHLQDLSGRISRARHNE 356
+S++ E+H +E R +++ +++ Q+L R + NE
Sbjct: 397 QRVAALSKAEERHGNIEERLRQMEAQLEEKNQELQRARQREKMNE 441
>gi|4505983 PTPRF interacting protein alpha 1 isoform b [Homo
sapiens]
Length = 1202
Score = 37.4 bits (85), Expect = 0.021
Identities = 67/285 (23%), Positives = 125/285 (43%), Gaps = 46/285 (16%)
Query: 101 LDEDGEKEARL-IRNLNVILAKYGLDGKKDARQVTSNSLSGTQEDGLDDPRLEKLWHKAK 159
LDE + R+ + +++ + G K+ N+ T DG+ D E+ +
Sbjct: 174 LDEKVRERLRVALERCSLLEEELGATHKELMILKEQNNQKKTLTDGVLDINHEQE-NTPS 232
Query: 160 TSGKFSGEELDKLWREFLHHKEKVHEYNVLLETLSRTEEIHENVISPSDLSDIKGSVLHS 219
TSGK S + L H+E + + L E +S+ S + + S L S
Sbjct: 233 TSGKRSSDGS-------LSHEEDLAKVIELQEIISKQSR------EQSQMKERLAS-LSS 278
Query: 220 RHTELKEKLRSINQGL-------DRLRRVSHQGYSTEAEFEEPRVIDLWDLAQSA----- 267
TEL+E L + + L +L+R + + + + EE R+ L +A
Sbjct: 279 HVTELEEDLDTARKDLIKSEEMNTKLQRDVREAMAQKEDMEE-RITTLEKRYLAAQREAT 337
Query: 268 ---NLTDK-ELEAFREELKHFEAKIEKHNHYQKQLEIAHEKL----RHAESVGDGER--- 316
+L DK E E ++ H + + +K+ Q++LE+A +KL R AE++ + E
Sbjct: 338 SVHDLNDKLENEIANKDSMHRQTE-DKNRQLQERLELAEQKLQQTLRKAETLPEVEAELA 396
Query: 317 -----VSRSREKHALLEGRTKELGYTVKKHLQDLSGRISRARHNE 356
+S++ E+H +E R +++ +++ Q+L R + NE
Sbjct: 397 QRVAALSKAEERHGNIEERLRQMEAQLEEKNQELQRARQREKMNE 441
>gi|66773344 hypothetical protein LOC140710 [Homo sapiens]
Length = 1016
Score = 36.2 bits (82), Expect = 0.046
Identities = 68/301 (22%), Positives = 123/301 (40%), Gaps = 46/301 (15%)
Query: 79 LHADLKIQERDELAWKKLKLDGLDEDGEKEARLIRNLNVILAKYGLDGKKDARQVTSNSL 138
LH +L++ E+ K+ +L+ +E+ E RLI LAK L + + + S
Sbjct: 75 LHKELEVVEK-----KRARLE--EENEELRQRLIETE---LAKQVLQTELERPREHSLKK 124
Query: 139 SGTQEDGLDDPR---------LEKLWHKAKTSGKFSGEELDKLWREFLHHKEKVHEYNVL 189
GT+ G D + L+ H AK ++L KL +E KE++ +Y L
Sbjct: 125 RGTRSLGKADKKTLVQEDSADLKCQLHFAKEESALMCKKLTKLAKENDSMKEELLKYRSL 184
Query: 190 LETLSRTEEIHENVISPSDLSDIKGSVLHSRHTELKEKLRSINQGLDRLRR------VSH 243
L ++ +S +L+D HSR TELK L+ + + + L R V +
Sbjct: 185 YGDL-------DSALSAEELADAP----HSRETELKVHLKLVEEEANLLSRRIVELEVEN 233
Query: 244 QGYSTEAEFEEPR-------VIDLWDLAQSANLTDKELEAFREELKHFEAKIEKHNHYQK 296
+G E + + L A + L R L+ E + E
Sbjct: 234 RGLRAEMDDMKDHGGGCGGPEARLAFSALGGGECGESLAELRRHLQFVEEEAELLRRSSA 293
Query: 297 QLEIAHEKLRHAESVGDGER---VSRSREKHALLEGRTKELGYTVKKHLQDLSGRISRAR 353
+LE ++ L + + E V+ S + ++L ++E K + +LSG++ + +
Sbjct: 294 ELEDQNKLLLNELAKFRSEHELDVALSEDSCSVLSEPSQEELAAAKLQIGELSGKVKKLQ 353
Query: 354 H 354
+
Sbjct: 354 Y 354
>gi|32455252 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
isoform 2 [Homo sapiens]
Length = 454
Score = 35.8 bits (81), Expect = 0.061
Identities = 42/208 (20%), Positives = 81/208 (38%), Gaps = 33/208 (15%)
Query: 150 RLEKLWHKAKTSGKFSGEELDKLWREFLHH--KEKVHEYNVLLET--LSRTEEIHENVIS 205
+L K++H+ G FS E ++H E + +YN L+ L + ++ +
Sbjct: 109 KLIKIFHRDGKYG-FSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVV 167
Query: 206 PSDLSDIKGSVLHSRHTELKEKLRSINQGLDRLRRVSHQGYSTEAEFEEPRVIDLWDLAQ 265
D + G LH +T+ +EK R ++ + R S Q
Sbjct: 168 KEDNIEAVGKKLHEYNTQFQEKSREYDRLYEEYTRTS----------------------Q 205
Query: 266 SANLTDKELEAFREELKHFEAKIEKHNHYQKQLEIAHEKLRHAESVGDGERVSRSREKHA 325
+ +EAF E +K FE + + Y K E + + G+ + + R +
Sbjct: 206 EIQMKRTAIEAFNETIKIFEEQCQTQERYSK------EYIEKFKREGNEKEIQRIMHNYD 259
Query: 326 LLEGRTKELGYTVKKHLQDLSGRISRAR 353
L+ R E+ + ++ +DL + + R
Sbjct: 260 KLKSRISEIIDSRRRLEEDLKKQAAEYR 287
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.133 0.381
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,022,285
Number of Sequences: 37866
Number of extensions: 667057
Number of successful extensions: 2757
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 217
Number of HSP's that attempted gapping in prelim test: 2533
Number of HSP's gapped (non-prelim): 437
length of query: 357
length of database: 18,247,518
effective HSP length: 103
effective length of query: 254
effective length of database: 14,347,320
effective search space: 3644219280
effective search space used: 3644219280
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.