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Search of human proteins with 4504643
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4504643 interleukin 12 receptor, beta 2 precursor [Homo
sapiens]
(862 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4504643 interleukin 12 receptor, beta 2 precursor [Homo sapiens] 1788 0.0
gi|28610147 interleukin 6 signal transducer isoform 1 precursor ... 167 3e-41
gi|4503081 colony stimulating factor 3 receptor isoform a precur... 158 2e-38
gi|27437045 colony stimulating factor 3 receptor isoform d precu... 155 2e-37
gi|24496783 colony stimulating factor 3 receptor isoform c precu... 154 4e-37
gi|27437042 colony stimulating factor 3 receptor isoform b precu... 152 2e-36
gi|4557040 oncostatin M receptor [Homo sapiens] 137 3e-32
gi|4504993 leukemia inhibitory factor receptor precursor [Homo s... 126 1e-28
gi|189083786 leukemia inhibitory factor receptor precursor [Homo... 126 1e-28
gi|4759328 class I cytokine receptor [Homo sapiens] 125 2e-28
gi|115430248 gp130-like monocyte receptor [Homo sapiens] 122 2e-27
gi|28610149 interleukin 6 signal transducer isoform 2 precursor ... 91 6e-18
gi|24430212 interleukin 23 receptor precursor [Homo sapiens] 78 4e-14
gi|4758062 cytokine receptor-like factor 1 [Homo sapiens] 74 6e-13
gi|21359935 Down syndrome cell adhesion molecule like 1 [Homo sa... 73 1e-12
gi|119220552 sidekick 1 [Homo sapiens] 72 2e-12
gi|222352127 sidekick 2 [Homo sapiens] 65 4e-10
gi|81158226 neuronal cell adhesion molecule isoform A precursor ... 65 4e-10
gi|81158224 neuronal cell adhesion molecule isoform B precursor ... 65 4e-10
gi|4506309 protein tyrosine phosphatase, receptor type, D isofor... 62 2e-09
gi|18860890 protein tyrosine phosphatase, receptor type, D isofo... 62 2e-09
gi|18860892 protein tyrosine phosphatase, receptor type, D isofo... 62 2e-09
gi|93141047 collagen, type XII, alpha 1 long isoform precursor [... 62 3e-09
gi|51093381 leptin receptor isoform 3 [Homo sapiens] 61 5e-09
gi|51093379 leptin receptor isoform 2 [Homo sapiens] 61 5e-09
gi|40254464 leptin receptor isoform 1 [Homo sapiens] 61 5e-09
gi|20127422 Down syndrome cell adhesion molecule isoform CHD2-42... 60 1e-08
gi|110349719 titin isoform N2-A [Homo sapiens] 56 1e-07
gi|110349717 titin isoform novex-2 [Homo sapiens] 56 1e-07
gi|110349713 titin isoform novex-1 [Homo sapiens] 56 1e-07
>gi|4504643 interleukin 12 receptor, beta 2 precursor [Homo sapiens]
Length = 862
Score = 1788 bits (4631), Expect = 0.0
Identities = 862/862 (100%), Positives = 862/862 (100%)
Query: 1 MAHTFRGCSLAFMFIITWLLIKAKIDACKRGDVTVKPSHVILLGSTVNITCSLKPRQGCF 60
MAHTFRGCSLAFMFIITWLLIKAKIDACKRGDVTVKPSHVILLGSTVNITCSLKPRQGCF
Sbjct: 1 MAHTFRGCSLAFMFIITWLLIKAKIDACKRGDVTVKPSHVILLGSTVNITCSLKPRQGCF 60
Query: 61 HYSRRNKLILYKFDRRINFHHGHSLNSQVTGLPLGTTLFVCKLACINSDEIQICGAEIFV 120
HYSRRNKLILYKFDRRINFHHGHSLNSQVTGLPLGTTLFVCKLACINSDEIQICGAEIFV
Sbjct: 61 HYSRRNKLILYKFDRRINFHHGHSLNSQVTGLPLGTTLFVCKLACINSDEIQICGAEIFV 120
Query: 121 GVAPEQPQNLSCIQKGEQGTVACTWERGRDTHLYTEYTLQLSGPKNLTWQKQCKDIYCDY 180
GVAPEQPQNLSCIQKGEQGTVACTWERGRDTHLYTEYTLQLSGPKNLTWQKQCKDIYCDY
Sbjct: 121 GVAPEQPQNLSCIQKGEQGTVACTWERGRDTHLYTEYTLQLSGPKNLTWQKQCKDIYCDY 180
Query: 181 LDFGINLTPESPESNFTAKVTAVNSLGSSSSLPSTFTFLDIVRPLPPWDIRIKFQKASVS 240
LDFGINLTPESPESNFTAKVTAVNSLGSSSSLPSTFTFLDIVRPLPPWDIRIKFQKASVS
Sbjct: 181 LDFGINLTPESPESNFTAKVTAVNSLGSSSSLPSTFTFLDIVRPLPPWDIRIKFQKASVS 240
Query: 241 RCTLYWRDEGLVLLNRLRYRPSNSRLWNMVNVTKAKGRHDLLDLKPFTEYEFQISSKLHL 300
RCTLYWRDEGLVLLNRLRYRPSNSRLWNMVNVTKAKGRHDLLDLKPFTEYEFQISSKLHL
Sbjct: 241 RCTLYWRDEGLVLLNRLRYRPSNSRLWNMVNVTKAKGRHDLLDLKPFTEYEFQISSKLHL 300
Query: 301 YKGSWSDWSESLRAQTPEEEPTGMLDVWYMKRHIDYSRQQISLFWKNLSVSEARGKILHY 360
YKGSWSDWSESLRAQTPEEEPTGMLDVWYMKRHIDYSRQQISLFWKNLSVSEARGKILHY
Sbjct: 301 YKGSWSDWSESLRAQTPEEEPTGMLDVWYMKRHIDYSRQQISLFWKNLSVSEARGKILHY 360
Query: 361 QVTLQELTGGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAG 420
QVTLQELTGGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAG
Sbjct: 361 QVTLQELTGGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAG 420
Query: 421 LLAPRQVSANSEGMDNILVTWQPPRKDPSAVQEYVVEWRELHPGGDTQVPLNWLRSRPYN 480
LLAPRQVSANSEGMDNILVTWQPPRKDPSAVQEYVVEWRELHPGGDTQVPLNWLRSRPYN
Sbjct: 421 LLAPRQVSANSEGMDNILVTWQPPRKDPSAVQEYVVEWRELHPGGDTQVPLNWLRSRPYN 480
Query: 481 VSALISENIKSYICYEIRVYALSGDQGGCSSILGNSKHKAPLSGPHINAITEEKGSILIS 540
VSALISENIKSYICYEIRVYALSGDQGGCSSILGNSKHKAPLSGPHINAITEEKGSILIS
Sbjct: 481 VSALISENIKSYICYEIRVYALSGDQGGCSSILGNSKHKAPLSGPHINAITEEKGSILIS 540
Query: 541 WNSIPVQEQMGCLLHYRIYWKERDSNSQPQLCEIPYRVSQNSHPINSLQPRVTYVLWMTA 600
WNSIPVQEQMGCLLHYRIYWKERDSNSQPQLCEIPYRVSQNSHPINSLQPRVTYVLWMTA
Sbjct: 541 WNSIPVQEQMGCLLHYRIYWKERDSNSQPQLCEIPYRVSQNSHPINSLQPRVTYVLWMTA 600
Query: 601 LTAAGESSHGNEREFCLQGKANWMAFVAPSICIAIIMVGIFSTHYFQQKVFVLLAALRPQ 660
LTAAGESSHGNEREFCLQGKANWMAFVAPSICIAIIMVGIFSTHYFQQKVFVLLAALRPQ
Sbjct: 601 LTAAGESSHGNEREFCLQGKANWMAFVAPSICIAIIMVGIFSTHYFQQKVFVLLAALRPQ 660
Query: 661 WCSREIPDPANSTCAKKYPIAEEKTQLPLDRLLIDWPTPEDPEPLVISEVLHQVTPVFRH 720
WCSREIPDPANSTCAKKYPIAEEKTQLPLDRLLIDWPTPEDPEPLVISEVLHQVTPVFRH
Sbjct: 661 WCSREIPDPANSTCAKKYPIAEEKTQLPLDRLLIDWPTPEDPEPLVISEVLHQVTPVFRH 720
Query: 721 PPCSNWPQREKGIQGHQASEKDMMHSASSPPPPRALQAESRQLVDLYKVLESRGSDPKPE 780
PPCSNWPQREKGIQGHQASEKDMMHSASSPPPPRALQAESRQLVDLYKVLESRGSDPKPE
Sbjct: 721 PPCSNWPQREKGIQGHQASEKDMMHSASSPPPPRALQAESRQLVDLYKVLESRGSDPKPE 780
Query: 781 NPACPWTVLPAGDLPTHDGYLPSNIDDLPSHEAPLADSLEELEPQHISLSVFPSSSLHPL 840
NPACPWTVLPAGDLPTHDGYLPSNIDDLPSHEAPLADSLEELEPQHISLSVFPSSSLHPL
Sbjct: 781 NPACPWTVLPAGDLPTHDGYLPSNIDDLPSHEAPLADSLEELEPQHISLSVFPSSSLHPL 840
Query: 841 TFSCGDKLTLDQLKMRCDSLML 862
TFSCGDKLTLDQLKMRCDSLML
Sbjct: 841 TFSCGDKLTLDQLKMRCDSLML 862
>gi|28610147 interleukin 6 signal transducer isoform 1 precursor
[Homo sapiens]
Length = 918
Score = 167 bits (424), Expect = 3e-41
Identities = 168/640 (26%), Positives = 264/640 (41%), Gaps = 63/640 (9%)
Query: 60 FHYSRRNKLILYKFDRRINFHHGHSLNSQVTGLPLGTTLFVCKLACINSDEIQICGAEIF 119
F + I+ + + F SLN Q+T C + E + G I
Sbjct: 72 FTIPKEQYTIINRTASSVTFTDIASLNIQLT----------CNILTFGQLEQNVYGITII 121
Query: 120 VGVAPEQPQNLSCIQKGEQGTVACTWERGRDTHLYTEYTLQLSGPKNLTWQKQCKDIYCD 179
G+ PE+P+NLSCI E + C W+ GR+THL T +TL+ + + K
Sbjct: 122 SGLPPEKPKNLSCIVN-EGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKR---- 176
Query: 180 YLDFGINLTPESPES---NFTAKVTAVNSLGSSSSLPSTFTFLDIVRPLPPWDIRIKFQK 236
D + T + N V A N+LG +S F + V+P PP ++ + +
Sbjct: 177 --DTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSE 234
Query: 237 ASVSRCTLYWRDEGL----VLLNRLRYRPSNSRLWNMV---NVTKAKGRHDLLDLKPFTE 289
S L W + + +L ++YR ++ W+ + + + + DLKPFTE
Sbjct: 235 ELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTE 294
Query: 290 YEFQISSKLHLYKGSWSDWSESLRAQTPEEEPTGMLDVWYMKRHIDYSRQQ----ISLFW 345
Y F+I KG WSDWSE T E+ P+ WY ID S Q + L W
Sbjct: 295 YVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWY---KIDPSHTQGYRTVQLVW 351
Query: 346 KNLSVSEARGKILHYQVTLQELTGGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGS 405
K L EA GKIL Y+VT LT K+ QN T + + TV + ++ N G
Sbjct: 352 KTLPPFEANGKILDYEVT---LTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGK 408
Query: 406 SLPTRINIMNLCEAGLLAPRQVSANSEGMDNIL-VTWQPPRKDPSAVQEYVVEWRELHPG 464
S + + C+ P + + DN+L V W PR+ +V++Y++EW L
Sbjct: 409 S-DAAVLTIPACDFQATHP-VMDLKAFPKDNMLWVEWTTPRE---SVKKYILEWCVL--S 461
Query: 465 GDTQVPLNWLRSRPYNVSALISENIKSYICYEIRVYALSGD-QGGCSSILGNSKHKAPLS 523
+W + + N+ CY I V + D G SI K P
Sbjct: 462 DKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSK 521
Query: 524 GPHINAITEEKGSILISWNSIPVQEQMGCLLHYRIYWKERDSNSQPQLCEIPYRVSQNSH 583
GP + K ++ W+ +PV Q G + +Y I+++ N + S +
Sbjct: 522 GPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE----TAVNVDSSHTEY 577
Query: 584 PINSLQPRVTYVLWMTALTAAGESSHGNEREFC----LQGKANWMAFVAPSICIAIIMVG 639
++SL Y++ M A T G G E F QG+ A V P +C+A ++
Sbjct: 578 TLSSLTSDTLYMVRMAAYTDEG-GKDGPEFTFTTPKFAQGEIE--AIVVP-VCLAFLLTT 633
Query: 640 IFSTHYFQQKVFVLLAALRPQWCSREIPDPANSTCAKKYP 679
+ + K ++ + P +PDP+ S A+ P
Sbjct: 634 LLGVLFCFNKRDLIKKHIWP-----NVPDPSKSHIAQWSP 668
>gi|4503081 colony stimulating factor 3 receptor isoform a precursor
[Homo sapiens]
Length = 836
Score = 158 bits (399), Expect = 2e-38
Identities = 212/854 (24%), Positives = 338/854 (39%), Gaps = 104/854 (12%)
Query: 8 CSLAFMFIITWLLIKAKIDACKRGDVTVKPSHVILLGSTVNITCSLKPRQGCFHYSRRNK 67
CSL + +I LL+ ++ C G ++V + ++ LG + +C +K Q C H +
Sbjct: 7 CSLTWAALII-LLLPGSLEEC--GHISVS-APIVHLGDPITASCIIK--QNCSHLDPEPQ 60
Query: 68 LI------LYKFDRRINFHHGHSLNSQVTGLPLGTTLFVCKLACIN-SDEIQICG-AEIF 119
++ L R+ G + LP C+N + +QI E+
Sbjct: 61 ILWRLGAELQPGGRQQRLSDG--TQESIITLPHLNHTQAFLSCCLNWGNSLQILDQVELR 118
Query: 120 VGVAPEQPQNLSCIQKGEQGTVACTWERGRDTHLYTEYTLQLSGPKNLTWQKQCKDIYCD 179
G P P NLSC+ ++ C WE G +THL T +TL K+ + C+
Sbjct: 119 AGYPPAIPHNLSCLMNLTTSSLICQWEPGPETHLPTSFTL-----KSFKSRGNCQTQGDS 173
Query: 180 YLDFGINLTPESPES-------------NFTAKVTAVNSLGSSSSLPSTFTFLDIVRPLP 226
LD P+ +S N V A N+LG+S S +D+V+ P
Sbjct: 174 ILD----CVPKDGQSHCCIPRKHLLLYQNMGIWVQAENALGTSMSPQLCLDPMDVVKLEP 229
Query: 227 PW----DIRIKFQKASVSRCTLYWR--DEGLVLLNR--LRYRPSNSRL-WNMVNVTKAKG 277
P D + L W GL + + LR++P W +V +
Sbjct: 230 PMLRTMDPSPEAAPPQAGCLQLCWEPWQPGLHINQKCELRHKPQRGEASWALVGPLPLEA 289
Query: 278 -RHDLLDLKPFTEYEFQISSKLHLYKGSWSDWSESLRAQTPEEEPTGMLDVWYMKRHIDY 336
+++L L P T Y QI G WSDWS SL +T E PT LD W+ +R +D
Sbjct: 290 LQYELCGLLPATAYTLQIRCIRWPLPGHWSDWSPSLELRTTERAPTVRLDTWWRQRQLD- 348
Query: 337 SRQQISLFWKNLSVSEARGKILHYQVTLQEL-TGGKAMTQNITGHTSWTTVIPRTGNWAV 395
+ + LFWK + + E G+I Y V+ + G + T S T +P V
Sbjct: 349 -PRTVQLFWKPVPLEEDSGRIQGYVVSWRPSGQAGAILPLCNTTELSCTFHLPSEAQ-EV 406
Query: 396 AVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKDPSAVQEYV 455
A+ A NS G+S PT + E+ A ++ A + ++ V W+PP P Q YV
Sbjct: 407 ALVAYNSAGTSRPTPV---VFSESRGPALTRLHAMARDPHSLWVGWEPPNPWP---QGYV 460
Query: 456 VEWRELHPGGDTQVPLNW-LRSRPYNVSALISENIKSYICYEIRVYALSGDQGGCSS-IL 513
+EW L P + W + L+ ENI+ + YEI V L D G S +
Sbjct: 461 IEW-GLGPPSASNSNKTWRMEQNGRATGFLLKENIRPFQLYEIIVTPLYQDTMGPSQHVY 519
Query: 514 GNSKHKAPLSGPHINAITEEKGSILISWNSIPVQEQMGCLLHYRIYWKERDSNSQPQLCE 573
S+ AP P ++ K + W P + L HY I+W +N+Q Q
Sbjct: 520 AYSQEMAPSHAPELHLKHIGKTWAQLEWVPEPPELGKSPLTHYTIFW----TNAQNQSFS 575
Query: 574 IPYRVSQNSHPINSLQPRVTYVLWMTALTAAGESSHGNEREFCLQGKANWMAFVAPSICI 633
S ++ L+P Y + + A + AG ++ L + + + + +
Sbjct: 576 AILNASSRGFVLHGLEPASLYHIHLMAASQAGATNSTVLTLMTLTPEGSELHIILGLFGL 635
Query: 634 AIIMVGIFSTHYFQQKVFVLLAALRPQWCSREIPDPANSTCAKKYP--IAEEKTQLP--- 688
+++ + T + + P W S +PDPA+S+ P + E+ QLP
Sbjct: 636 LLLLTCLCGTAW----LCCSPNRKNPLWPS--VPDPAHSSLGSWVPTIMEEDAFQLPGLG 689
Query: 689 ------------LDRLLIDWPTPEDPEPLVISEVLHQVTPVFRHPP--CSNWPQREKGIQ 734
++ + W + E + ++ T V + P S PQ + G
Sbjct: 690 TPPITKLTVLEEDEKKPVPWESHNSSETCGLPTLVQ--TYVLQGDPRAVSTQPQSQSG-T 746
Query: 735 GHQASEKDMMHSASSPPPPRALQAESRQLVDLYKVLESRGSDPKPENPACPW-TVLPAGD 793
Q ++ S +SP P L+ +S Q + G P P++ W P G
Sbjct: 747 SDQVLYGQLLGSPTSPGPGHYLRCDSTQPL-------LAGLTPSPKSYENLWFQASPLGT 799
Query: 794 LPTHDGYLPSNIDD 807
L T PS DD
Sbjct: 800 LVTP---APSQEDD 810
>gi|27437045 colony stimulating factor 3 receptor isoform d
precursor [Homo sapiens]
Length = 783
Score = 155 bits (392), Expect = 2e-37
Identities = 183/717 (25%), Positives = 292/717 (40%), Gaps = 73/717 (10%)
Query: 8 CSLAFMFIITWLLIKAKIDACKRGDVTVKPSHVILLGSTVNITCSLKPRQGCFHYSRRNK 67
CSL + +I LL+ ++ C G ++V + ++ LG + +C +K Q C H +
Sbjct: 7 CSLTWAALII-LLLPGSLEEC--GHISVS-APIVHLGDPITASCIIK--QNCSHLDPEPQ 60
Query: 68 LI------LYKFDRRINFHHGHSLNSQVTGLPLGTTLFVCKLACIN-SDEIQICG-AEIF 119
++ L R+ G + LP C+N + +QI E+
Sbjct: 61 ILWRLGAELQPGGRQQRLSDG--TQESIITLPHLNHTQAFLSCCLNWGNSLQILDQVELR 118
Query: 120 VGVAPEQPQNLSCIQKGEQGTVACTWERGRDTHLYTEYTLQLSGPKNLTWQKQCKDIYCD 179
G P P NLSC+ ++ C WE G +THL T +TL K+ + C+
Sbjct: 119 AGYPPAIPHNLSCLMNLTTSSLICQWEPGPETHLPTSFTL-----KSFKSRGNCQTQGDS 173
Query: 180 YLDFGINLTPESPES-------------NFTAKVTAVNSLGSSSSLPSTFTFLDIVRPLP 226
LD P+ +S N V A N+LG+S S +D+V+ P
Sbjct: 174 ILD----CVPKDGQSHCCIPRKHLLLYQNMGIWVQAENALGTSMSPQLCLDPMDVVKLEP 229
Query: 227 PW----DIRIKFQKASVSRCTLYWR--DEGLVLLNR--LRYRPSNSRL-WNMVNVTKAKG 277
P D + L W GL + + LR++P W +V +
Sbjct: 230 PMLRTMDPSPEAAPPQAGCLQLCWEPWQPGLHINQKCELRHKPQRGEASWALVGPLPLEA 289
Query: 278 -RHDLLDLKPFTEYEFQISSKLHLYKGSWSDWSESLRAQTPEEEPTGMLDVWYMKRHIDY 336
+++L L P T Y QI G WSDWS SL +T E PT LD W+ +R +D
Sbjct: 290 LQYELCGLLPATAYTLQIRCIRWPLPGHWSDWSPSLELRTTERAPTVRLDTWWRQRQLD- 348
Query: 337 SRQQISLFWKNLSVSEARGKILHYQVTLQEL-TGGKAMTQNITGHTSWTTVIPRTGNWAV 395
+ + LFWK + + E G+I Y V+ + G + T S T +P V
Sbjct: 349 -PRTVQLFWKPVPLEEDSGRIQGYVVSWRPSGQAGAILPLCNTTELSCTFHLPSEAQ-EV 406
Query: 396 AVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKDPSAVQEYV 455
A+ A NS G+S PT + E+ A ++ A + ++ V W+PP P Q YV
Sbjct: 407 ALVAYNSAGTSRPTPV---VFSESRGPALTRLHAMARDPHSLWVGWEPPNPWP---QGYV 460
Query: 456 VEWRELHPGGDTQVPLNW-LRSRPYNVSALISENIKSYICYEIRVYALSGDQGGCSS-IL 513
+EW L P + W + L+ ENI+ + YEI V L D G S +
Sbjct: 461 IEW-GLGPPSASNSNKTWRMEQNGRATGFLLKENIRPFQLYEIIVTPLYQDTMGPSQHVY 519
Query: 514 GNSKHKAPLSGPHINAITEEKGSILISWNSIPVQEQMGCLLHYRIYWKERDSNSQPQLCE 573
S+ AP P ++ K + W P + L HY I+W +N+Q Q
Sbjct: 520 AYSQEMAPSHAPELHLKHIGKTWAQLEWVPEPPELGKSPLTHYTIFW----TNAQNQSFS 575
Query: 574 IPYRVSQNSHPINSLQPRVTYVLWMTALTAAGESSHGNEREFCLQGKANWMAFVAPSICI 633
S ++ L+P Y + + A + AG ++ L + + + + +
Sbjct: 576 AILNASSRGFVLHGLEPASLYHIHLMAASQAGATNSTVLTLMTLTPEGSELHIILGLFGL 635
Query: 634 AIIMVGIFSTHYFQQKVFVLLAALRPQWCSREIPDPANSTCAKKYP--IAEEKTQLP 688
+++ + T + + P W S +PDPA+S+ P + E+ QLP
Sbjct: 636 LLLLTCLCGTAW----LCCSPNRKNPLWPS--VPDPAHSSLGSWVPTIMEEDAFQLP 686
>gi|24496783 colony stimulating factor 3 receptor isoform c
precursor [Homo sapiens]
Length = 863
Score = 154 bits (388), Expect = 4e-37
Identities = 181/715 (25%), Positives = 289/715 (40%), Gaps = 71/715 (9%)
Query: 8 CSLAFMFIITWLLIKAKIDACKRGDVTVKPSHVILLGSTVNITCSLKPRQGCFHYSRRNK 67
CSL + +I LL+ ++ C G ++V + ++ LG + +C +K Q C H +
Sbjct: 7 CSLTWAALII-LLLPGSLEEC--GHISVS-APIVHLGDPITASCIIK--QNCSHLDPEPQ 60
Query: 68 LI------LYKFDRRINFHHGHSLNSQVTGLPLGTTLFVCKLACIN-SDEIQICG-AEIF 119
++ L R+ G + LP C+N + +QI E+
Sbjct: 61 ILWRLGAELQPGGRQQRLSDG--TQESIITLPHLNHTQAFLSCCLNWGNSLQILDQVELR 118
Query: 120 VGVAPEQPQNLSCIQKGEQGTVACTWERGRDTHLYTEYTLQLSGPKNLTWQKQCKDIYCD 179
G P P NLSC+ ++ C WE G +THL T +TL K+ + C+
Sbjct: 119 AGYPPAIPHNLSCLMNLTTSSLICQWEPGPETHLPTSFTL-----KSFKSRGNCQTQGDS 173
Query: 180 YLDFGINLTPESPES-------------NFTAKVTAVNSLGSSSSLPSTFTFLDIVRPLP 226
LD P+ +S N V A N+LG+S S +D+V+ P
Sbjct: 174 ILD----CVPKDGQSHCCIPRKHLLLYQNMGIWVQAENALGTSMSPQLCLDPMDVVKLEP 229
Query: 227 PW----DIRIKFQKASVSRCTLYWR--DEGLVLLNR--LRYRPSNSRL-WNMVNVTKAKG 277
P D + L W GL + + LR++P W +V +
Sbjct: 230 PMLRTMDPSPEAAPPQAGCLQLCWEPWQPGLHINQKCELRHKPQRGEASWALVGPLPLEA 289
Query: 278 -RHDLLDLKPFTEYEFQISSKLHLYKGSWSDWSESLRAQTPEEEPTGMLDVWYMKRHIDY 336
+++L L P T Y QI G WSDWS SL +T E PT LD W+ +R +D
Sbjct: 290 LQYELCGLLPATAYTLQIRCIRWPLPGHWSDWSPSLELRTTERAPTVRLDTWWRQRQLD- 348
Query: 337 SRQQISLFWKNLSVSEARGKILHYQVTLQEL-TGGKAMTQNITGHTSWTTVIPRTGNWAV 395
+ + LFWK + + E G+I Y V+ + G + T S T +P V
Sbjct: 349 -PRTVQLFWKPVPLEEDSGRIQGYVVSWRPSGQAGAILPLCNTTELSCTFHLPSEAQ-EV 406
Query: 396 AVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKDPSAVQEYV 455
A+ A NS G+S PT + E+ A ++ A + ++ V W+PP P Q YV
Sbjct: 407 ALVAYNSAGTSRPTPV---VFSESRGPALTRLHAMARDPHSLWVGWEPPNPWP---QGYV 460
Query: 456 VEWRELHPGGDTQVPLNW-LRSRPYNVSALISENIKSYICYEIRVYALSGDQGGCSS-IL 513
+EW L P + W + L+ ENI+ + YEI V L D G S +
Sbjct: 461 IEW-GLGPPSASNSNKTWRMEQNGRATGFLLKENIRPFQLYEIIVTPLYQDTMGPSQHVY 519
Query: 514 GNSKHKAPLSGPHINAITEEKGSILISWNSIPVQEQMGCLLHYRIYWKERDSNSQPQLCE 573
S+ AP P ++ K + W P + L HY I+W +N+Q Q
Sbjct: 520 AYSQEMAPSHAPELHLKHIGKTWAQLEWVPEPPELGKSPLTHYTIFW----TNAQNQSFS 575
Query: 574 IPYRVSQNSHPINSLQPRVTYVLWMTALTAAGESSHGNEREFCLQGKANWMAFVAPSICI 633
S ++ L+P Y + + A + AG ++ L + + + + +
Sbjct: 576 AILNASSRGFVLHGLEPASLYHIHLMAASQAGATNSTVLTLMTLTPEGSELHIILGLFGL 635
Query: 634 AIIMVGIFSTHYFQQKVFVLLAALRPQWCSREIPDPANSTCAKKYPIAEEKTQLP 688
+++ + T + + P W S +PDPA+S+ P E+ P
Sbjct: 636 LLLLTCLCGTAW----LCCSPNRKNPLWPS--VPDPAHSSLGSWVPTIMEELPGP 684
>gi|27437042 colony stimulating factor 3 receptor isoform b
precursor [Homo sapiens]
Length = 769
Score = 152 bits (383), Expect = 2e-36
Identities = 168/635 (26%), Positives = 261/635 (41%), Gaps = 65/635 (10%)
Query: 8 CSLAFMFIITWLLIKAKIDACKRGDVTVKPSHVILLGSTVNITCSLKPRQGCFHYSRRNK 67
CSL + +I LL+ ++ C G ++V + ++ LG + +C +K Q C H +
Sbjct: 7 CSLTWAALII-LLLPGSLEEC--GHISVS-APIVHLGDPITASCIIK--QNCSHLDPEPQ 60
Query: 68 LI------LYKFDRRINFHHGHSLNSQVTGLPLGTTLFVCKLACIN-SDEIQICG-AEIF 119
++ L R+ G + LP C+N + +QI E+
Sbjct: 61 ILWRLGAELQPGGRQQRLSDG--TQESIITLPHLNHTQAFLSCCLNWGNSLQILDQVELR 118
Query: 120 VGVAPEQPQNLSCIQKGEQGTVACTWERGRDTHLYTEYTLQLSGPKNLTWQKQCKDIYCD 179
G P P NLSC+ ++ C WE G +THL T +TL K+ + C+
Sbjct: 119 AGYPPAIPHNLSCLMNLTTSSLICQWEPGPETHLPTSFTL-----KSFKSRGNCQTQGDS 173
Query: 180 YLDFGINLTPESPES-------------NFTAKVTAVNSLGSSSSLPSTFTFLDIVRPLP 226
LD P+ +S N V A N+LG+S S +D+V+ P
Sbjct: 174 ILD----CVPKDGQSHCCIPRKHLLLYQNMGIWVQAENALGTSMSPQLCLDPMDVVKLEP 229
Query: 227 PW----DIRIKFQKASVSRCTLYWR--DEGLVLLNR--LRYRPSNSRL-WNMVNVTKAKG 277
P D + L W GL + + LR++P W +V +
Sbjct: 230 PMLRTMDPSPEAAPPQAGCLQLCWEPWQPGLHINQKCELRHKPQRGEASWALVGPLPLEA 289
Query: 278 -RHDLLDLKPFTEYEFQISSKLHLYKGSWSDWSESLRAQTPEEEPTGMLDVWYMKRHIDY 336
+++L L P T Y QI G WSDWS SL +T E PT LD W+ +R +D
Sbjct: 290 LQYELCGLLPATAYTLQIRCIRWPLPGHWSDWSPSLELRTTERAPTVRLDTWWRQRQLD- 348
Query: 337 SRQQISLFWKNLSVSEARGKILHYQVTLQEL-TGGKAMTQNITGHTSWTTVIPRTGNWAV 395
+ + LFWK + + E G+I Y V+ + G + T S T +P V
Sbjct: 349 -PRTVQLFWKPVPLEEDSGRIQGYVVSWRPSGQAGAILPLCNTTELSCTFHLPSEAQ-EV 406
Query: 396 AVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKDPSAVQEYV 455
A+ A NS G+S PT + E+ A ++ A + ++ V W+PP P Q YV
Sbjct: 407 ALVAYNSAGTSRPTPV---VFSESRGPALTRLHAMARDPHSLWVGWEPPNPWP---QGYV 460
Query: 456 VEWRELHPGGDTQVPLNW-LRSRPYNVSALISENIKSYICYEIRVYALSGDQGGCSS-IL 513
+EW L P + W + L+ ENI+ + YEI V L D G S +
Sbjct: 461 IEW-GLGPPSASNSNKTWRMEQNGRATGFLLKENIRPFQLYEIIVTPLYQDTMGPSQHVY 519
Query: 514 GNSKHKAPLSGPHINAITEEKGSILISWNSIPVQEQMGCLLHYRIYWKERDSNSQPQLCE 573
S+ AP P ++ K + W P + L HY I+W +N+Q Q
Sbjct: 520 AYSQEMAPSHAPELHLKHIGKTWAQLEWVPEPPELGKSPLTHYTIFW----TNAQNQSFS 575
Query: 574 IPYRVSQNSHPINSLQPRVTYVLWMTALTAAGESS 608
S ++ L+P Y + + A + AG ++
Sbjct: 576 AILNASSRGFVLHGLEPASLYHIHLMAASQAGATN 610
>gi|4557040 oncostatin M receptor [Homo sapiens]
Length = 979
Score = 137 bits (346), Expect = 3e-32
Identities = 158/639 (24%), Positives = 267/639 (41%), Gaps = 90/639 (14%)
Query: 81 HGHSLNSQVTGLPLGTTLFV--------CKLACINSDEIQICGAEIFVGVAPEQPQNLSC 132
HG L+ VT L + F+ C+ + N E + G +FV E+P++ SC
Sbjct: 187 HGEQLDPHVTAFNLNSVPFIRNKGTNIYCEASQGNVSE-GMKGIVLFVSKVLEEPKDFSC 245
Query: 133 IQKGEQGTVACTWERGRDTHL------YTEYTL--QLSGPKNLTWQKQCKDIYCDYLDFG 184
+ + T+ CTW+ G DT L YTL SG K L K +C++
Sbjct: 246 -ETEDFKTLHCTWDPGTDTALGWSKQPSQSYTLFESFSGEKKLCTHKN----WCNW---- 296
Query: 185 INLTPESPES-NFTAKVTAVNSLGSSSSLPSTFTFLDIVRPLPPWDIRIKFQKASVSRCT 243
+T +S E+ NFT + A N L S+ F V + P+ + F+ + +
Sbjct: 297 -QITQDSQETYNFT--LIAENYL-RKRSVNILFNLTHRVYLMNPFSVN--FENVNATNAI 350
Query: 244 LYWRDEGL----VLLNRLRYRPSNSRLWNMVNVTKAKGRHDLLDLKPFTEYEFQI--SSK 297
+ W+ + L ++ + V++ K G + L +L+P TEY ++ +
Sbjct: 351 MTWKVHSIRNNFTYLCQIELHGEGKMMQYNVSI-KVNGEYFLSELEPATEYMARVRCADA 409
Query: 298 LHLYKGSWSDWSESLRAQTPEEEPTGMLDVWYMKRHIDYSRQQISLFWKNLSVSEARGKI 357
H +K WS+WS T E P+ DVW + ++ ++LFWK LS A GKI
Sbjct: 410 SHFWK--WSEWSGQ-NFTTLEAAPSEAPDVWRIVS-LEPGNHTVTLFWKPLSKLHANGKI 465
Query: 358 LHYQVTLQELTG-GKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNL 416
L Y V ++ L + +I + T +I ++ + V A NS G+S P + +++
Sbjct: 466 LFYNVVVENLDKPSSSELHSIPAPANSTKLILDRCSYQICVIANNSVGAS-PASVIVISA 524
Query: 417 CEAGLLAPRQVSANSEGMDNILVTWQPPRKDPSAVQEYVVEWRELHPGGDTQVPLNWLRS 476
+ A +EG ++W+P P V YVV+W + D W
Sbjct: 525 DPENKEVEEERIAGTEG--GFSLSWKP---QPGDVIGYVVDWCDHTQ--DVLGDFQWKNV 577
Query: 477 RPYNVSALISEN-IKSYICYEIRVYALSGDQGGC--SSILGNSKHKAPLSGPHINAITEE 533
P S +IS + + + Y+ R+Y LS + C G S+ AP PH+ T
Sbjct: 578 GPNTTSTVISTDAFRPGVRYDFRIYGLSTKRIACLLEKKTGYSQELAPSDNPHVLVDTLT 637
Query: 534 KGSILISWNSIPVQEQMGCLLHYRIYWKERDSNSQPQLCE---------IPYRV---SQN 581
S +SW + Q G + Y +Y K + P+ + Y++ +
Sbjct: 638 SHSFTLSWKDYSTESQPGFIQGYHVYLKSKARQCHPRFEKAVLSDGSECCKYKIDNPEEK 697
Query: 582 SHPINSLQPRVTYVLWMTALTAAGESSHGNEREFCLQGKANWMA--FVAPSI-CIAIIMV 638
+ +++L+P Y ++T T+AGE + + + M + P + C+ +IMV
Sbjct: 698 ALIVDNLKPESFYEFFITPFTSAGEGPSATFTKVTTPDEHSSMLIHILLPMVFCVLLIMV 757
Query: 639 GIFSTHYFQQKVFVLLAALRPQW----CSREIPDPANST 673
+ L+ QW C +IPDP S+
Sbjct: 758 ---------------MCYLKSQWIKETCYPDIPDPYKSS 781
>gi|4504993 leukemia inhibitory factor receptor precursor [Homo
sapiens]
Length = 1097
Score = 126 bits (316), Expect = 1e-28
Identities = 156/596 (26%), Positives = 251/596 (42%), Gaps = 70/596 (11%)
Query: 110 EIQICGAEIFVGVAPEQPQNLSCIQKGEQGTVACTWERGRDTHLY----TEYTLQLSGPK 165
E I G IF G P+ PQ L+C + + + C+W GR T L T YTL S
Sbjct: 319 EDNIFGTVIFAGYPPDTPQQLNC-ETHDLKEIICSWNPGRVTALVGPRATSYTLVESFSG 377
Query: 166 NLTWQKQCKDIYCDYLDFGINLTPESPESNFTAKVTAVNSLGSSSSLPSTFTFLDIVRPL 225
K+ + + + P NFT + A N LG S S + V P
Sbjct: 378 KYVRLKRAEAPTNESYQLLFQMLPNQEIYNFT--LNAHNPLGRSQST-ILVNITEKVYPH 434
Query: 226 PPWDIRIKFQKASVSRCTLYWRDEG----LVLLNRLRYRPSNSRLWNMVNVTKAKGRHD- 280
P ++K ++ + L W G + L + + SNS + NVT KG +
Sbjct: 435 TPTSFKVKDINSTAVK--LSWHLPGNFAKINFLCEIEIKKSNS-VQEQRNVT-IKGVENS 490
Query: 281 -----LLDLKPFTEYEFQISSKLHLYKGSWSDWSESLRAQTPEEEPTGMLDVWYMKRHID 335
L L P+T Y F+I + WS WS + T E P+ D W R
Sbjct: 491 SYLVALDKLNPYTLYTFRIRCSTETF-WKWSKWSNKKQHLTTEASPSKGPDTW---REWS 546
Query: 336 YSRQQISLFWKNLSVSEARGKILHYQVTLQELTGGKAMTQNITGHTSWTTVIPRTGNWAV 395
+ + ++WK L ++EA GKIL Y V+ +++++ I + ++ +
Sbjct: 547 SDGKNLIIYWKPLPINEANGKILSYNVSCSSDEETQSLSE-IPDPQHKAEIRLDKNDYII 605
Query: 396 AVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKDPSAVQEYV 455
+V A NS GSS P++I M + L + V IL+TW DP+ +YV
Sbjct: 606 SVVAKNSVGSSPPSKIASMEIPNDDLKIEQVVGMGK----GILLTWH---YDPNMTCDYV 658
Query: 456 VEWRELHPGGDTQVPLNWLRSRPYNVSALI--SENIKSYICYEIRVYALSGDQGG--CSS 511
++W + ++W R P N + + S+ + I Y +Y +QG S
Sbjct: 659 IKW--CNSSRSEPCLMDW-RKVPSNSTETVIESDEFRPGIRYNFFLYGCR-NQGYQLLRS 714
Query: 512 ILGNSKHKAPLSGPHINAITEEKGSILISWNSIPVQEQMGCLLHYRIYW--KERDSNSQP 569
++G + AP+ P+ SIL+ W IPV+E G L Y Y+ ERD++
Sbjct: 715 MIGYIEELAPIVAPNFTVEDTSADSILVKWEDIPVEELRGFLRGYLFYFGKGERDTSKMR 774
Query: 570 QL----CEIPYR----VSQNSHPINSLQPRVTYVLWMTALTAAGESSHGNEREFCLQGKA 621
L +I + +SQ + I LQ + +Y L + A T G G E+ + K
Sbjct: 775 VLESGRSDIKVKNITDISQKTLRIADLQGKTSYHLVLRAYTDGGV---GPEKSMYVVTKE 831
Query: 622 NWMA-FVAPSICIAI-IMVGIFSTHYFQQKVFVLLAALRPQWCSR----EIPDPAN 671
N + +A I +A+ ++VG+ ++ +L + +W +IP+P N
Sbjct: 832 NSVGLIIAILIPVAVAVIVGVVTS---------ILCYRKREWIKETFYPDIPNPEN 878
>gi|189083786 leukemia inhibitory factor receptor precursor [Homo
sapiens]
Length = 1097
Score = 126 bits (316), Expect = 1e-28
Identities = 156/596 (26%), Positives = 251/596 (42%), Gaps = 70/596 (11%)
Query: 110 EIQICGAEIFVGVAPEQPQNLSCIQKGEQGTVACTWERGRDTHLY----TEYTLQLSGPK 165
E I G IF G P+ PQ L+C + + + C+W GR T L T YTL S
Sbjct: 319 EDNIFGTVIFAGYPPDTPQQLNC-ETHDLKEIICSWNPGRVTALVGPRATSYTLVESFSG 377
Query: 166 NLTWQKQCKDIYCDYLDFGINLTPESPESNFTAKVTAVNSLGSSSSLPSTFTFLDIVRPL 225
K+ + + + P NFT + A N LG S S + V P
Sbjct: 378 KYVRLKRAEAPTNESYQLLFQMLPNQEIYNFT--LNAHNPLGRSQST-ILVNITEKVYPH 434
Query: 226 PPWDIRIKFQKASVSRCTLYWRDEG----LVLLNRLRYRPSNSRLWNMVNVTKAKGRHD- 280
P ++K ++ + L W G + L + + SNS + NVT KG +
Sbjct: 435 TPTSFKVKDINSTAVK--LSWHLPGNFAKINFLCEIEIKKSNS-VQEQRNVT-IKGVENS 490
Query: 281 -----LLDLKPFTEYEFQISSKLHLYKGSWSDWSESLRAQTPEEEPTGMLDVWYMKRHID 335
L L P+T Y F+I + WS WS + T E P+ D W R
Sbjct: 491 SYLVALDKLNPYTLYTFRIRCSTETF-WKWSKWSNKKQHLTTEASPSKGPDTW---REWS 546
Query: 336 YSRQQISLFWKNLSVSEARGKILHYQVTLQELTGGKAMTQNITGHTSWTTVIPRTGNWAV 395
+ + ++WK L ++EA GKIL Y V+ +++++ I + ++ +
Sbjct: 547 SDGKNLIIYWKPLPINEANGKILSYNVSCSSDEETQSLSE-IPDPQHKAEIRLDKNDYII 605
Query: 396 AVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKDPSAVQEYV 455
+V A NS GSS P++I M + L + V IL+TW DP+ +YV
Sbjct: 606 SVVAKNSVGSSPPSKIASMEIPNDDLKIEQVVGMGK----GILLTWH---YDPNMTCDYV 658
Query: 456 VEWRELHPGGDTQVPLNWLRSRPYNVSALI--SENIKSYICYEIRVYALSGDQGG--CSS 511
++W + ++W R P N + + S+ + I Y +Y +QG S
Sbjct: 659 IKW--CNSSRSEPCLMDW-RKVPSNSTETVIESDEFRPGIRYNFFLYGCR-NQGYQLLRS 714
Query: 512 ILGNSKHKAPLSGPHINAITEEKGSILISWNSIPVQEQMGCLLHYRIYW--KERDSNSQP 569
++G + AP+ P+ SIL+ W IPV+E G L Y Y+ ERD++
Sbjct: 715 MIGYIEELAPIVAPNFTVEDTSADSILVKWEDIPVEELRGFLRGYLFYFGKGERDTSKMR 774
Query: 570 QL----CEIPYR----VSQNSHPINSLQPRVTYVLWMTALTAAGESSHGNEREFCLQGKA 621
L +I + +SQ + I LQ + +Y L + A T G G E+ + K
Sbjct: 775 VLESGRSDIKVKNITDISQKTLRIADLQGKTSYHLVLRAYTDGGV---GPEKSMYVVTKE 831
Query: 622 NWMA-FVAPSICIAI-IMVGIFSTHYFQQKVFVLLAALRPQWCSR----EIPDPAN 671
N + +A I +A+ ++VG+ ++ +L + +W +IP+P N
Sbjct: 832 NSVGLIIAILIPVAVAVIVGVVTS---------ILCYRKREWIKETFYPDIPNPEN 878
>gi|4759328 class I cytokine receptor [Homo sapiens]
Length = 636
Score = 125 bits (313), Expect = 2e-28
Identities = 131/497 (26%), Positives = 204/497 (41%), Gaps = 40/497 (8%)
Query: 232 IKFQKASVSRCTLYWRD----EGLVLLNRLRYRPSNSRLWNMVNV---TKAKGRHDLLDL 284
+ F + T++W VL+ + YR W ++ T ++ DL
Sbjct: 137 VDFSEDDPLEATVHWAPPTWPSHKVLICQFHYRRCQEAAWTLLEPELKTIPLTPVEIQDL 196
Query: 285 KPFTEYEFQISSKLHLYKGSWSDWSESLRAQTPEEEPTGMLDVWYMKRHIDY-SRQQISL 343
+ T Y+ ++ + W +WS L QTP P DVW ++ L
Sbjct: 197 ELATGYKVYGRCRMEKEEDLWGEWSPILSFQTPPSAPK---DVWVSGNLCGTPGGEEPLL 253
Query: 344 FWKNLSVSEARGKILHYQVTLQELTGGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSK 403
WK A G + + GG+ ++ G T ++IP WA VSA N+
Sbjct: 254 LWK------APGPCVQVSYKVWFWVGGRELSPE--GITCCCSLIPSGAEWA-RVSAVNA- 303
Query: 404 GSSLPTRINIMNLCEAGLLAPRQVSANS-EGMDNILVTWQPPRKDPSAVQEYVVEWRELH 462
+S N+ +C APR V+ +S G +LVTWQP +P E+VV+W
Sbjct: 304 -TSWEPLTNLSLVCLDSASAPRSVAVSSIAGSTELLVTWQPGPGEPL---EHVVDWAR-- 357
Query: 463 PGGDTQVPLNWLRSRPYNVSALISENIKSYICYEIRVYALSGDQ-GGCSSILGNSKHKAP 521
GD LNW+R P N+SAL+ N + Y I V A+S SS+ G + AP
Sbjct: 358 -DGDPLEKLNWVRLPPGNLSALLPGNFTVGVPYRITVTAVSASGLASASSVWGFREELAP 416
Query: 522 LSGPHINAITEEK-GSILISWNSIPVQEQMGCLLHYRIYWKERDSNSQPQLCEIPYRVSQ 580
L GP + + + G+ I+W +P + G L HY + S + P +C VS
Sbjct: 417 LVGPTLWRLQDAPPGTPAIAWGEVPRHQLRGHLTHYTLC---AQSGTSPSVC---MNVSG 470
Query: 581 NSHPINSLQ-PRVTYVLWMTALTAAGESSHGNEREFCLQGKA-NWMAFVAPSICIAIIMV 638
N+ + P LW+TA T AG+ G L W + ++
Sbjct: 471 NTQSVTLPDLPWGPCELWVTASTIAGQGPPGPILRLHLPDNTLRWKVLPGILFLWGLFLL 530
Query: 639 GIFSTHYFQQKVFVLLAALRPQWCSREIPDPANSTCAKKYPIAEEKTQLPLDRLLIDWPT 698
G + + + L + P+W ++PDPANS+ + + + Q PL L I
Sbjct: 531 GCGLSLATSGRCYHLRHKVLPRWVWEKVPDPANSSSGQPHMEQVPEAQ-PLGDLPILEVE 589
Query: 699 PEDPEPLVISEVLHQVT 715
+P P++ S Q T
Sbjct: 590 EMEPPPVMESSQPAQAT 606
>gi|115430248 gp130-like monocyte receptor [Homo sapiens]
Length = 764
Score = 122 bits (305), Expect = 2e-27
Identities = 150/624 (24%), Positives = 253/624 (40%), Gaps = 72/624 (11%)
Query: 124 PEQPQNLSCIQKGEQGTVACTWERGRDTHLYTEYTLQLS---GPK--NLTWQKQCKDIYC 178
P +P+N+SC+ + + CTW G++T YT+YT++ + G K N T +
Sbjct: 54 PAKPENISCVYYYRKN-LTCTWSPGKETS-YTQYTVKRTYAFGEKHDNCTTNSSTSENRA 111
Query: 179 DYLDFGINLTPESPESNFTAKVTAVNSLGSSSSLPSTFTFLDIVRPLPPWDIRIKFQKAS 238
F +T N+T +V A N G S + + +I + PP R+K
Sbjct: 112 SCSFFLPRITIPD---NYTIEVEAENGDGVIKSHMTYWRLENIAKTEPPKIFRVKPVLGI 168
Query: 239 VSRCTLYWRDEGLV-----LLNRLRYRPSNSRLWNMVNVTKAKG----RHDLLDLKPFTE 289
+ W L L LR+R NS W VN K + ++L L+PFTE
Sbjct: 169 KRMIQIEWIKPELAPVSSDLKYTLRFRTVNSTSWMEVNFAKNRKDKNQTYNLTGLQPFTE 228
Query: 290 YEFQISSKLHLYKGSWSDWSESLRAQTPEEEPTGMLDVWYMKRHIDYS-RQQISLFWKNL 348
Y + + K WSDWS+ T EE P G L++W + + + R+ + L WK
Sbjct: 229 YVIALRCAVKESK-FWSDWSQEKMGMTEEEAPCG-LELWRVLKPAEADGRRPVRLLWKKA 286
Query: 349 SVSEARGKILHYQV----------TLQELTGGKAMTQNITGHTSWTTVIPRTGNWAVAVS 398
+ K L Y + T T + + ++ G + W ++I
Sbjct: 287 RGAPVLEKTLGYNIWYYPESNTNLTETMNTTNQQLELHLGGESFWVSMI----------- 335
Query: 399 AANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKDPSAVQEYVVEW 458
+ NS G S + I + E + A D ++V WQ D V +++EW
Sbjct: 336 SYNSLGKSPVATLRIPAIQEKSFQCIEVMQA-CVAEDQLVVKWQSSALD---VNTWMIEW 391
Query: 459 RELHPGGDTQ-VPLNWLRSRPYNVSALISENIKSYICYEIRVYALSGDQ-GGCSSILGNS 516
P D++ L+W + + +K + CY I VY + D+ G SI +
Sbjct: 392 ---FPDVDSEPTTLSWESVSQATNWTIQQDKLKPFWCYNISVYPMLHDKVGEPYSIQAYA 448
Query: 517 KHKAPLSGPHINAITEEKGSILISWNSIPVQEQMGCLLHYRIYWKERDSNSQPQLCEIPY 576
K P GP ++ I+W IP E+ G + +Y I+++ +
Sbjct: 449 KEGVPSEGPETKVENIGVKTVTITWKEIPKSERKGIICNYTIFYQAEGGKGFSK----TV 504
Query: 577 RVSQNSHPINSLQPRVTYVLWMTALTAAGESSHGNEREFCLQGKANWMAFVAPSICIAII 636
S + + SL+ + +Y++ + A T+AG ++G F + + + S+ +
Sbjct: 505 NSSILQYGLESLKRKTSYIVQVMASTSAG-GTNGTSINFKTLSFSVFEIILITSLIGGGL 563
Query: 637 MVGIFSTHYFQQKVFVLLAALRPQWCSREIPDPANSTCA--------KKYPIAEEKTQLP 688
++ I T + K L L C +P+PA S+ A K + E +
Sbjct: 564 LILIILTVAYGLKKPNKLTHL----CWPTVPNPAESSIATWHGDDFKDKLNLKESDDSVN 619
Query: 689 L-DRLLIDWPTPEDPEPLVISEVL 711
DR+L TP D LVI +++
Sbjct: 620 TEDRILKPCSTPSD--KLVIDKLV 641
>gi|28610149 interleukin 6 signal transducer isoform 2 precursor
[Homo sapiens]
Length = 329
Score = 90.5 bits (223), Expect = 6e-18
Identities = 74/270 (27%), Positives = 115/270 (42%), Gaps = 27/270 (10%)
Query: 60 FHYSRRNKLILYKFDRRINFHHGHSLNSQVTGLPLGTTLFVCKLACINSDEIQICGAEIF 119
F + I+ + + F SLN Q+T C + E + G I
Sbjct: 72 FTIPKEQYTIINRTASSVTFTDIASLNIQLT----------CNILTFGQLEQNVYGITII 121
Query: 120 VGVAPEQPQNLSCIQKGEQGTVACTWERGRDTHLYTEYTLQLSGPKNLTWQKQCKDIYCD 179
G+ PE+P+NLSCI E + C W+ GR+THL T +TL+ + + K
Sbjct: 122 SGLPPEKPKNLSCIVN-EGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKR---- 176
Query: 180 YLDFGINLTPESPES---NFTAKVTAVNSLGSSSSLPSTFTFLDIVRPLPPWDIRIKFQK 236
D + T + N V A N+LG +S F + V+P PP ++ + +
Sbjct: 177 --DTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSE 234
Query: 237 ASVSRCTLYWRDEGL----VLLNRLRYRPSNSRLWNMV---NVTKAKGRHDLLDLKPFTE 289
S L W + + +L ++YR ++ W+ + + + + DLKPFTE
Sbjct: 235 ELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTE 294
Query: 290 YEFQISSKLHLYKGSWSDWSESLRAQTPEE 319
Y F+I KG WSDWSE T E+
Sbjct: 295 YVFRIRCMKEDGKGYWSDWSEEASGITYED 324
>gi|24430212 interleukin 23 receptor precursor [Homo sapiens]
Length = 629
Score = 77.8 bits (190), Expect = 4e-14
Identities = 74/305 (24%), Positives = 127/305 (41%), Gaps = 30/305 (9%)
Query: 31 GDVTVKPSHVILLGSTVNITCSLKPRQGCFHYSRRNKLILYKFDRRINFHHGHSLNSQVT 90
G + V+P+ + +G ++I C Q + KL YK + F +N
Sbjct: 32 GHIWVEPATIFKMGMNISIYC-----QAAIKNCQPRKLHFYKNGIKERFQITR-INKTTA 85
Query: 91 GLPLGTTL-----FVCKLACINS-DEIQICGAEIFVGVAPEQPQNLSCIQKGEQGTVACT 144
L L C C E ICG +I G P+ P ++C+ G + CT
Sbjct: 86 RLWYKNFLEPHASMYCTAECPKHFQETLICGKDISSGYPPDIPDEVTCVIYEYSGNMTCT 145
Query: 145 WERGRDTHLYTEYTLQLSGPKNLTWQKQCKDIYCDYLDFGINLTPESPE--SNFTAKVTA 202
W G+ T++ T+Y + + K+L +++ + + Y IN++ +S + + V A
Sbjct: 146 WNAGKLTYIDTKYVVHV---KSLETEEEQQYLTSSY----INISTDSLQGGKKYLVWVQA 198
Query: 203 VNSLGSSSSLPSTFTFLDIVRPLPPWDIRIKFQKASVSRCTLYWRDEGLV--LLNRLRYR 260
N+LG S DIV P R + A+V + +YW + + + +RY+
Sbjct: 199 ANALGMEESKQLQIHLDDIVIPSAAVISRAETINATVPKTIIYWDSQTTIEKVSCEMRYK 258
Query: 261 PSNSRLWNM----VNVTKAKGRHDLLDLKPFTEYEFQISSKLHLYKGSWSDWSESLRAQT 316
+ ++ WN+ N T + L+P +Y FQ+ + K W WS +T
Sbjct: 259 ATTNQTWNVKEFDTNFTYV--QQSEFYLEPNIKYVFQVRCQ-ETGKRYWQPWSSLFFHKT 315
Query: 317 PEEEP 321
PE P
Sbjct: 316 PETVP 320
>gi|4758062 cytokine receptor-like factor 1 [Homo sapiens]
Length = 422
Score = 73.9 bits (180), Expect = 6e-13
Identities = 68/239 (28%), Positives = 104/239 (43%), Gaps = 25/239 (10%)
Query: 103 LACINSDEIQICGAEIFVGVAPEQPQNLSCIQKGEQGTVACTWERGR--DTHLYTEYTLQ 160
L C D + G+ ++VG+ PE+P N+SC K + + C W G +T L+T Y+L+
Sbjct: 114 LVCHARDGSILAGSCLYVGLPPEKPVNISCWSKNMK-DLTCRWTPGAHGETFLHTNYSLK 172
Query: 161 LSGPKNLTWQKQCKDIYC-DYLDFGINLTPESPE----SNFTAKVTAVNSLGSSSSLPST 215
L W Q D C +Y G + + + + V A N LGS+ S T
Sbjct: 173 Y----KLRWYGQ--DNTCEEYHTVGPHSCHIPKDLALFTPYEIWVEATNRLGSARSDVLT 226
Query: 216 FTFLDIVRPLPPWDIRIKFQKASVSRCTLYW------RDEGLVLLNRLRYRPSNSRLWNM 269
LD+V PP D+ + + ++ W +D ++RYR +S W +
Sbjct: 227 LDILDVVTTDPPPDVHVSRVGGLEDQLSVRWVSPPALKDFLFQAKYQIRYRVEDSVDWKV 286
Query: 270 VNVTKAKGRHDLLDLKPFTEYEFQI-SSKLHLY----KGSWSDWSESLRAQTPEEEPTG 323
V+ + L LKP T Y Q+ + +Y G WS+WS A TP E G
Sbjct: 287 VDDVSNQTSCRLAGLKPGTVYFVQVRCNPFGIYGSKKAGIWSEWSHPTAASTPRSERPG 345
>gi|21359935 Down syndrome cell adhesion molecule like 1 [Homo
sapiens]
Length = 2113
Score = 72.8 bits (177), Expect = 1e-12
Identities = 119/510 (23%), Positives = 199/510 (39%), Gaps = 43/510 (8%)
Query: 128 QNLSCIQKGEQGTVACTWERGRDTHLYTEYTLQLSGPKNLTWQKQCKDIYCDYLDFGINL 187
+ L+C +GE+ + WE+G DT + + ++ + KD D + + L
Sbjct: 866 KELNCTARGER-PIIIRWEKG-DTVIDPDRVMR--------YAIATKD-NGDEVVSTLKL 914
Query: 188 TPESPESNFTAKVTAVNSLGSSSSLPSTFTFLDIVRPLPPWDIRIKFQKASVSRCTLYWR 247
P + A+NS G L L + P P ++ I+ KA R
Sbjct: 915 KPADRGDSVFFSCHAINSYGEDRGLIQ----LTVQEPPDPPELEIREVKARSMNLRWTQR 970
Query: 248 DEGLVLLNRLRYRPSN-SRLWNMV----NVTKAKGRHDLLDLKPFTEYEFQISSKLHLYK 302
+G ++ N S W+ N++ + +++DL P + Y ++ S K
Sbjct: 971 FDGNSIITGFDIEYKNKSDSWDFKQSTRNISPTINQANIVDLHPASVYSIRMYS---FNK 1027
Query: 303 GSWSDWSESLRAQTPEEEPTGM-LDVWYMKRHIDYSRQQISLFWKNLSVSEARGKILHYQ 361
S+ S+ L T E P G +DV + Q I + WK G I YQ
Sbjct: 1028 IGRSEPSKELTISTEEAAPDGPPMDVTLQP----VTSQSIQVTWKAPKKELQNGVIRGYQ 1083
Query: 362 VTLQELTGGKAMTQNI-----TGHTSWTTV--IPRTGNWAVAVSAANSKGSS-LPTRINI 413
+ +E + G +I TG + T+ + + + V V A N G+ + IN
Sbjct: 1084 IGYRENSPGSNGQYSIVEMKATGDSEVYTLDNLKKFAQYGVVVQAFNRAGTGPSSSEINA 1143
Query: 414 MNLCEAGLLAPRQVSANSEGMDNILVTW-QPPRKDPSAVQE-YVVEWRELHPGGDTQVPL 471
L + P V A S D +++W +PPR + V + Y V + L+ G+
Sbjct: 1144 TTLEDVPSQPPENVRALSITSDVAVISWSEPPRSTLNGVLKGYRVIFWSLYVDGEWGEMQ 1203
Query: 472 NWLRSRPYNVSALISENIKSYICYEIRVYALSGDQGGCSSILGNSKHKAPLSGPHINAIT 531
N +R V E +Y ++ Y +GD S + +K P I A+
Sbjct: 1204 NITTTRE-RVELRGMEKFTNY-SVQVLAYTQAGDGVRSSVLYIQTKEDVPGPPAGIKAVP 1261
Query: 532 EEKGSILISWNSIPVQEQMGCLLHYRIYWKERDSNSQPQLCEIPYRVSQNSHPINSLQPR 591
S+++SW +P + G + Y I+ S QP E Q + I L
Sbjct: 1262 SSASSVVVSW--LPPTKPNGVIRKYTIFCSSPGSG-QPAPSEYETSPEQLFYRIAHLNRG 1318
Query: 592 VTYVLWMTALTAAGESSHGNEREFCLQGKA 621
Y+LW+ A+T+AG + + GKA
Sbjct: 1319 QQYLLWVAAVTSAGRGNSSEKVTIEPAGKA 1348
Score = 38.9 bits (89), Expect = 0.021
Identities = 55/222 (24%), Positives = 92/222 (41%), Gaps = 14/222 (6%)
Query: 219 LDIVRPLPPWDIRIKFQKASVSRCTLYW--RDEGLVLLNR--LRYRPSNSRLWNMVNVTK 274
++++ +PP R+ K S S TL W D G + L+Y NS W V ++
Sbjct: 1436 VNLLVQVPPDQPRLTVSKTSASSITLTWIPGDNGGSSIRGFVLQYSVDNSEEWKDVFISS 1495
Query: 275 AKGRHDLLDLKPFTEYEFQISSKLHLYKGSWSDWSESLRAQTPEEEPTGMLDVWYMKRHI 334
++ L LK T Y+ ++++K + G SE + A+T EP+ D ++ HI
Sbjct: 1496 SERSFKLDSLKCGTWYKVKLAAKNSVGSGR---ISEIIEAKTHGREPSFSKD-QHLFTHI 1551
Query: 335 DYSRQQISLFWKNLSVSEARGKILHYQVTLQELTGGKAMTQNITGHTSWTTVIPRTGNW- 393
+ + +++L N +L Y+ + + + N +G T + R W
Sbjct: 1552 NSTHARLNLQGWNNGGCPITAIVLEYRP--KGTWAWQGLRANSSGEVFLTEL--REATWY 1607
Query: 394 AVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMD 435
+ + A NS G T L G P SA EG D
Sbjct: 1608 ELRMRACNSAGCGNET-AQFATLDYDGSTIPPIKSAQGEGDD 1648
>gi|119220552 sidekick 1 [Homo sapiens]
Length = 2213
Score = 72.4 bits (176), Expect = 2e-12
Identities = 101/475 (21%), Positives = 198/475 (41%), Gaps = 57/475 (12%)
Query: 196 FTAKVTAVNSLGSSSSLPSTFTFLDIVR---PLPPWDIRIKFQKASVSRCTLYWRD---- 248
+ +V A +G+ +PST L+ + P PP +R+ F + ++ + W+
Sbjct: 1349 YELQVLAFTRIGNG--VPSTPLILERTKDDAPGPP--VRLVFPEVRLTSVRIVWQPPEEP 1404
Query: 249 EGLVLLNRLRYRPSNS--RLWNMVNVTKAKGRHDLLDLKPFTEYEFQISSKLHLYKGSWS 306
G++L ++ YR ++S + V V + DL P + Y F++S+K
Sbjct: 1405 NGIILGYQIAYRLASSSPHTFTTVEVGATVRQFTATDLAPESAYIFRLSAKTR------Q 1458
Query: 307 DWSESLRAQ--TPEEEPTGMLDVWYMKRHIDYSRQQISLFWKNLSVSEARGKILHYQVTL 364
W E L A T E+ + + + + + L W + S+ I ++ + +
Sbjct: 1459 GWGEPLEATVITTEKRERPAPPRELLVPQAEVTARSLRLQW--VPGSDGASPIRYFTMQV 1516
Query: 365 QELTGGKAMTQNIT-GHTSWTTVIPRTG---NWAVAVSAANSKGSS--LPTRINIMNLCE 418
+EL G+ T + + H + V+ R ++ + + A N G S + L +
Sbjct: 1517 RELPRGEWQTYSSSISHEATACVVDRLRPFTSYKLRLKATNDIGDSDFSSETEAVTTLQD 1576
Query: 419 AGLLAPRQVSANSEGMDNILVTWQPPRKDP--SAVQEYVVEWRELHPGGDTQVPLNWLRS 476
P VSA ++L+ WQPPR + +Q Y + +REL + L++
Sbjct: 1577 VPGEPPGSVSATPHTTSSVLIQWQPPRDESLNGLLQGYRIYYRELEYEAGSGTEAKTLKN 1636
Query: 477 --------------RPYNVSALIS----ENIKSYICYEI--RVYALSGDQGGCSSILGNS 516
+ N S+ + ++K Y YE+ Y + G+ + +
Sbjct: 1637 PIALHAELTAQSSFKTVNSSSTSTMCELTHLKKYRRYEVIMTAYNIIGESPASAPVEVFV 1696
Query: 517 KHKAPLSGPHINAITEEKGSIL-ISWNSIPVQEQMGCLLHYRIYWKERDSNSQPQLCEIP 575
AP P +T S L ++W+ P + Q G + Y+IY+ E DS ++ + ++
Sbjct: 1697 GEAAPAMAPQNVQVTPLTASQLEVTWDPPPPESQNGNIQGYKIYYWEADSQNETEKMKVL 1756
Query: 576 YRVSQNSHPINSLQPRVTYVLWMTALTAAGESSHGNEREFCLQGKANWMAFVAPS 630
+ + + + +L Y++ ++A AAG+ + + QG+ + A APS
Sbjct: 1757 F-LPEPVVRLKNLTSHTKYLVSISAFNAAGDGPKSDPQ----QGRTHQAAPGAPS 1806
Score = 52.0 bits (123), Expect = 2e-06
Identities = 46/193 (23%), Positives = 91/193 (47%), Gaps = 16/193 (8%)
Query: 422 LAPRQVSANSEGMDNILVTWQPP-----RKDPSAVQEYVVEWR-ELHPGGDTQVPLNWLR 475
+AP V+ + ++ + W P +P +V + WR +L QV + L
Sbjct: 1175 VAPTSVTVRTASETSLRLRWVPLPDSQYNGNPESVGYRIKYWRSDLQSSAVAQVVSDRLE 1234
Query: 476 SRPYNVSALISENIKSYICYEIRVYALSGDQGGCSS--ILGNSKHKAPLSGP-HINAITE 532
R + + E ++ ++ YE+++ A + G S + G ++ P + P +++A
Sbjct: 1235 -REFTI-----EELEEWMEYELQMQAFNAVGAGPWSEVVRGRTRESVPSAAPENVSAEAV 1288
Query: 533 EKGSILISWNSIPVQEQMGCLLHYRIYWKERDSNSQPQLCEIPYRVSQNSHPINSLQPRV 592
IL++W S+P Q+Q G +L Y+I ++ +D + +P+ + +Q S + L+ V
Sbjct: 1289 SSTQILLTWTSVPEQDQNGLILGYKILFRAKDLDPEPRSHIVRGNHTQ-SALLAGLRKFV 1347
Query: 593 TYVLWMTALTAAG 605
Y L + A T G
Sbjct: 1348 LYELQVLAFTRIG 1360
Score = 34.7 bits (78), Expect = 0.39
Identities = 54/284 (19%), Positives = 111/284 (39%), Gaps = 21/284 (7%)
Query: 191 SPESNFTAKVTAVNSLGSSSSLPSTFTFLDIVRPLPPWDIRIKFQKASVSRCTLYWRDEG 250
+P +++ ++ VN +G S PS+ + P + + AS + L W
Sbjct: 1139 TPYTHYRFRMKQVNIVGPSPYSPSSRVIQTLQAPPDVAPTSVTVRTASETSLRLRWVPLP 1198
Query: 251 LVLLN--------RLRYRPSNSRLWNMVNVTKAKGRHDLL--DLKPFTEYEFQISSKLHL 300
N R++Y S+ + + V + + +L+ + EYE Q+ + +
Sbjct: 1199 DSQYNGNPESVGYRIKYWRSDLQSSAVAQVVSDRLEREFTIEELEEWMEYELQMQAFNAV 1258
Query: 301 YKGSWSDWSESLRAQTPEEEPTGMLDVWYMKRHIDYSRQQISLFWKNLSVSEARGKILHY 360
G WS E +R +T E P+ + + S QI L W ++ + G IL Y
Sbjct: 1259 GAGPWS---EVVRGRTRESVPSAAPENVSAEA---VSSTQILLTWTSVPEQDQNGLILGY 1312
Query: 361 QVTLQELTGGKAMTQNIT--GHTSWTTV--IPRTGNWAVAVSAANSKGSSLPTRINIMNL 416
++ + +I HT + + + + + V A G+ +P+ I+
Sbjct: 1313 KILFRAKDLDPEPRSHIVRGNHTQSALLAGLRKFVLYELQVLAFTRIGNGVPSTPLILER 1372
Query: 417 CEAGLLAPR-QVSANSEGMDNILVTWQPPRKDPSAVQEYVVEWR 459
+ P ++ + ++ + WQPP + + Y + +R
Sbjct: 1373 TKDDAPGPPVRLVFPEVRLTSVRIVWQPPEEPNGIILGYQIAYR 1416
>gi|222352127 sidekick 2 [Homo sapiens]
Length = 2172
Score = 64.7 bits (156), Expect = 4e-10
Identities = 53/220 (24%), Positives = 103/220 (46%), Gaps = 15/220 (6%)
Query: 397 VSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQP-PRKDPSAVQE-- 453
V+ + S P+R I L +AP VS + ++ + W P P + + E
Sbjct: 1074 VNIVGTSPPSQPSR-KIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESV 1132
Query: 454 -YVVEWRELHPGGDTQVPLNWLR-SRPYNVSALISENIKSYICYEIRVYALSGDQGG--C 509
Y +++ G T + R R Y + E+++ + Y ++V A + G
Sbjct: 1133 GYKIKYSRSDGHGKTLSHVVQDRVERDYTI-----EDLEEWTEYRVQVQAFNAIGSGPWS 1187
Query: 510 SSILGNSKHKAPLSGP-HINAITEEKGSILISWNSIPVQEQMGCLLHYRIYWKERDSNSQ 568
+++G ++ P SGP +++A+ S+L+ W+ +P ++ G +L Y++ +KE+DS++Q
Sbjct: 1188 QTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQ 1247
Query: 569 PQLCEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAGESS 608
P+ + S S + L V Y + + A T G+ S
Sbjct: 1248 PRFWLVEGN-SSRSAQLTGLGKYVLYEVQVLAFTRIGDGS 1286
Score = 58.5 bits (140), Expect = 3e-08
Identities = 102/461 (22%), Positives = 187/461 (40%), Gaps = 54/461 (11%)
Query: 207 GSSSSLPSTFTFLDIVRPLPPWDIRIKFQKASVSRCTLYWRD----EGLVLLNRLRYRPS 262
GS S P LD V P PP + I F + + L W+ G++L ++ +R
Sbjct: 1285 GSPSHPPILERTLDDV-PGPP--MGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHR-L 1340
Query: 263 NSRLWNMVNV---TKAKGRHDLLDLKPFTEYEFQISSKLHLYKGSWSDWSESLRAQTPEE 319
N+ N V + ++ LKP + Y F+I+++ KG W + +E+L T E+
Sbjct: 1341 NTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTR--KG-WGEAAEAL-VVTTEK 1396
Query: 320 EPTGMLDVWYMKRHIDYSRQQISLFWKNLSVSEARGKILHYQVTLQELTGGK-AMTQNIT 378
M + D + + L W+ S+ + +Y + +EL G+ A+
Sbjct: 1397 RDRPQPPSRPMVQQEDVRARSVLLSWE--PGSDGLSPVRYYTIQTRELPSGRWALHSASV 1454
Query: 379 GHTSWTTVIPRTG---NWAVAVSAANSKGSS--LPTRINIMNLCEAGLLAPRQVSANSEG 433
H + + ++ R ++ V A N G S ++ L A AP +S
Sbjct: 1455 SHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHT 1514
Query: 434 MDNILVTWQPPRKDP--SAVQEYVVEWREL--------------HPGGDTQVPLNWLRSR 477
++L+ WQPP +D + + + +REL +PG + R
Sbjct: 1515 TTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMR 1574
Query: 478 PYNVSALIS---ENIKSYICYEIRVYALSGDQGGCSS-----ILGNSKHKAPLSGPHINA 529
+ +L +N+ + YEIR+ + G SS +G + A ++
Sbjct: 1575 NLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHG 1634
Query: 530 ITEEKGSILISWNSIPVQEQMGCLLHYRIYWKERDSNSQPQLCEIPYRVSQNSHPINSLQ 589
T + + ++W P+ Q G + Y+IY+ E + + + + +++NS + +L
Sbjct: 1635 ATATQ--LDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLF-LAENSVKLKNLT 1691
Query: 590 PRVTYVLWMTALTAAGESSHGNEREFCLQGKANWMAFVAPS 630
Y++ + A AAG+ R QG+ A APS
Sbjct: 1692 GYTAYMVSVAAFNAAGD----GPRSTPTQGQTQQAAPSAPS 1728
Score = 52.4 bits (124), Expect = 2e-06
Identities = 91/419 (21%), Positives = 162/419 (38%), Gaps = 72/419 (17%)
Query: 192 PESNFTAKVTAVNSLG---SSSSLPSTFTFLDIVRPLPPWDIRIKFQKASVSRCTLYWRD 248
PES + ++TA G ++ +L T D RP PP ++ + L W +
Sbjct: 1367 PESVYLFRITAQTRKGWGEAAEALVVTTEKRD--RPQPPSRPMVQQEDVRARSVLLSW-E 1423
Query: 249 EGLVLLNRLRY-----RPSNSRLWNMVNVTKAKGRHDLL--DLKPFTEYEFQISSKLHLY 301
G L+ +RY R S W + + + + + LKPFT Y+F++ + +
Sbjct: 1424 PGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIG 1483
Query: 302 KGSWSDWSESLRA--QTPEEEPTGMLDVWYMKRHIDYSRQQISLFWKNLSVSEARGKILH 359
+S+ SESL P+E PT +L V ++ + + W+ + + G +L
Sbjct: 1484 DSEFSEESESLTTLQAAPDEAPT-ILSV------TPHTTTSVLIRWQPPAEDKINGILLG 1536
Query: 360 YQVTLQELTGGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLPT---------- 409
+++ +EL + + + G T P WA S + + S P+
Sbjct: 1537 FRIRYREL-----LYEGLRGFTLRGINNP-GATWAELTSMYSMRNLSRPSLTQYELDNLN 1590
Query: 410 -------RINIMNLCEAG---------------LLAPRQVSANSEGMDNILVTWQPPRKD 447
R+++ N G APR V + + VTW+PP D
Sbjct: 1591 KHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLD 1650
Query: 448 P--SAVQEYVVEWRELHPGGDTQ-VPLNWLRSRPYNVSALISENIKSYICYEIRVYAL-- 502
+Q Y + + E G T+ V +L + +N+ Y Y + V A
Sbjct: 1651 SQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKL-----KNLTGYTAYMVSVAAFNA 1705
Query: 503 SGDQGGCSSILGNSKHKAPLSGPHINAITEEKGSILISWNSIPVQEQMGCLLHYRIYWK 561
+GD + G ++ AP + + S+ +SW + Q G L YR+ ++
Sbjct: 1706 AGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEA--PQFPNGILEGYRLVYE 1762
Score = 40.4 bits (93), Expect = 0.007
Identities = 83/450 (18%), Positives = 167/450 (37%), Gaps = 45/450 (10%)
Query: 191 SPESNFTAKVTAVNSLGSSSSLPSTFTFLDIVRPLPPWDIRIKFQKASVSRCTLYWRDEG 250
+P + ++ ++ VN +G+S + + P + + AS + L W
Sbjct: 1062 NPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLP 1121
Query: 251 LVLLN--------RLRYRPSNSRLWNMVNVTKAKGRHD--LLDLKPFTEYEFQISSKLHL 300
+ N +++Y S+ + +V + + D + DL+ +TEY Q+ + +
Sbjct: 1122 EMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAI 1181
Query: 301 YKGSWSDWSES-LRAQTPEEEPTGMLDVWYMKRHIDYSRQQISLFWKNLSVSEARGKILH 359
G WS R P PT + + + + + W + ++ G +L
Sbjct: 1182 GSGPWSQTVVGRTRESVPSSGPTNV-------SALATTSSSMLVRWSEVPEADRNGLVLG 1234
Query: 360 YQVTLQEL-TGGKAMTQNITGHTSWTTVIPRTGNWA---VAVSAANSKGSSLPTRINIMN 415
Y+V +E + + + G++S + + G + V V A G P+ I+
Sbjct: 1235 YKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILE 1294
Query: 416 LC-------EAGLLAPRQVSANSEGMDNILVTWQPPRKDPSAVQEYVVEWR-ELHPGGDT 467
G+L P +V S + + WQPP + Y + R
Sbjct: 1295 RTLDDVPGPPMGILFP-EVRTTS-----VRLIWQPPAAPNGIILAYQITHRLNTTTANTA 1348
Query: 468 QVPLNWLRSRPYNVSALISENIKSYICYEIRVYALSGDQGGCSSILGNSKHK---APLSG 524
V + +R Y + L E++ + I G +++ ++ + P S
Sbjct: 1349 TVEVLAPSARQYTATGLKPESV---YLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSR 1405
Query: 525 PHINAITEEKGSILISWNSIPVQEQMGCLLHYRIYWKERDSNSQPQLCEIPYRVSQNSHP 584
P + S+L+SW P + + + +Y I +E S + L + +S
Sbjct: 1406 PMVQQEDVRARSVLLSWE--PGSDGLSPVRYYTIQTRELPS-GRWALHSASVSHNASSFI 1462
Query: 585 INSLQPRVTYVLWMTALTAAGESSHGNERE 614
++ L+P +Y + A G+S E E
Sbjct: 1463 VDRLKPFTSYKFRVKATNDIGDSEFSEESE 1492
Score = 39.3 bits (90), Expect = 0.016
Identities = 69/334 (20%), Positives = 127/334 (38%), Gaps = 23/334 (6%)
Query: 284 LKPFTEYEFQISSKLHLYKGSWSDWSESLRAQTPEEEPTGMLDVWYMKRHIDYSRQQISL 343
L P Y+F++ + + KG +S +E R PEE PT + Q I +
Sbjct: 655 LVPARSYQFRLCAVNDVGKGQFSKDTE--RVSLPEEPPTAPPQNVIASGR---TNQSIMI 709
Query: 344 FWKNLSVSEARGKILHYQVT--LQELTGG---KAMTQNITGHTSWTTVIPRTGNWAVAVS 398
W+ S G + Y + L L G K +T + +I T N+ + V+
Sbjct: 710 QWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWT-NYEIEVA 768
Query: 399 AANSKGSSL-PTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKDPSAVQEYVVE 457
A NS G + +++ L + P V A + I TW P P +
Sbjct: 769 AYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAP--SPQFINGINQG 826
Query: 458 WRELHPGGDTQVPLNWLRSRPY---NVSALISENIKSYICY--EIRVYALSGDQGGCSSI 512
++ + + + + + +RP ++ +K + Y + + GD +
Sbjct: 827 YKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQ 886
Query: 513 LGNSKHKAPLSGPHINAITEEKGSILISWNSIPVQEQMGCLLHYRIYWKERDSNSQPQLC 572
L + P H++ S+ +SW E+ G L YRI W+E + +
Sbjct: 887 LVRTHEDVPGPVGHLSFSEILDTSLKVSWQE--PGEKNGILTGYRISWEEYNRTNTRVTH 944
Query: 573 EIPYRVSQNSHPINSLQPRVTYVLWMTALTAAGE 606
+P + + + L TY + + A+T+ G+
Sbjct: 945 YLPNVTLE--YRVTGLTALTTYTIEVAAMTSKGQ 976
Score = 33.9 bits (76), Expect = 0.67
Identities = 63/327 (19%), Positives = 122/327 (37%), Gaps = 41/327 (12%)
Query: 340 QISLFWKNLSVSEARGKILHYQVTLQELTGGK--------------AMTQNITGHTSWTT 385
Q+ + W+ + G I Y++ E G +N+TG+T++
Sbjct: 1639 QLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMV 1698
Query: 386 VIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPR 445
+ A +AA S PT+ +A AP V + ++ V+W+ P+
Sbjct: 1699 SV-------AAFNAAGDGPRSTPTQGQTQ---QAAPSAPSSVKFSELTTTSVNVSWEAPQ 1748
Query: 446 KDPSAVQEYVVEWRELHP--GGDTQVPLNWLRSRPYNVSALISENIKSYICYEIRVYALS 503
++ Y + + P G V ++ + P + +++ + Y R+ A +
Sbjct: 1749 FPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKV---KDLAEGVTYRFRIRAKT 1805
Query: 504 GDQGGC--SSILGNSKHKAPLSGPHINAITEEKGSILISWNSIPVQEQMGCLLHYRIYWK 561
G +++ AP P + I +I I W+S G + Y I +
Sbjct: 1806 FTYGPEIEANVTTGPGEGAP-GPPGVPIIVRYSSAIAIHWSS--GDPGKGPITRYVIEAR 1862
Query: 562 ERDSNSQPQLC-EIPYRVSQNSHPINSLQPRVTYVLWMTALTAAGESSHGNEREFCLQGK 620
D L +IP VS + ++ L+P V+Y + A+ G + + + K
Sbjct: 1863 PSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQK 1922
Query: 621 AN------WMAFVAPSICIAIIMVGIF 641
AN W V + + I++ +F
Sbjct: 1923 ANPFYEEWWFLVVIALVGLIFILLLVF 1949
>gi|81158226 neuronal cell adhesion molecule isoform A precursor
[Homo sapiens]
Length = 1304
Score = 64.7 bits (156), Expect = 4e-10
Identities = 61/239 (25%), Positives = 102/239 (42%), Gaps = 24/239 (10%)
Query: 392 NWAVAVSAANSKGSSLPTRINIMNLCEAGL--LAPRQVSANSEGMDNILVTWQPPR--KD 447
N++ V A NS G SLP+ + L +A P V DN+++TW+P +
Sbjct: 716 NYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFES 775
Query: 448 PSAVQEYVVEWRELHPGGDTQVPLNWLRSRPYNVSALISENIKSYICYEIRVYALSGDQG 507
+Y V WR+ GD + W NVS I +++ Y I+V AL+ D G
Sbjct: 776 NGPGLQYKVSWRQ--KDGDDE----WTSVVVANVSKYIVSGTPTFVPYLIKVQALN-DMG 828
Query: 508 GCSS---ILGNSKHKAPLSGP---HINAITEEKGSILISWNSIPVQEQMGCLLHYRIYWK 561
++G+S P+ P +N + + W+ +P++ G L YRIY+
Sbjct: 829 FAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEV--HWDPVPLKSIRGHLQGYRIYYW 886
Query: 562 ERDSNSQPQLCEIPYRV-----SQNSHPINSLQPRVTYVLWMTALTAAGESSHGNEREF 615
+ S+S+ I ++ S+ + L+P Y L + + GE +R F
Sbjct: 887 KTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVF 945
Score = 40.8 bits (94), Expect = 0.005
Identities = 68/345 (19%), Positives = 131/345 (37%), Gaps = 25/345 (7%)
Query: 282 LDLKPFTEYEFQISSKLHLYKGSWSDWSESL--RAQTPEEEPTGMLDVWYMKRHIDYSRQ 339
L L P+ Y F++ + + K S+ SE +A P++ PT + +
Sbjct: 709 LKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAV-------EGLGSEPD 761
Query: 340 QISLFWKNLSVSEARGKILHYQVTLQELTGGKAMTQNITGHTSWTTV--IPRTGNWAVAV 397
+ + WK L+ E+ G L Y+V+ ++ G T + + S V P + + V
Sbjct: 762 NLVITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTSVVVANVSKYIVSGTPTFVPYLIKV 821
Query: 398 SAANSKGSSLPTRINIMNLC--EAGLLAPRQVSANSEGMDNILVTWQP-PRKD-PSAVQE 453
A N G + P +M + ++AP V N V W P P K +Q
Sbjct: 822 QALNDMGFA-PEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQG 880
Query: 454 Y-VVEWRELHPG--GDTQVPLNWLRSRPYNVSALISENIKSYICYEIRVYALSGDQGGCS 510
Y + W+ + L + ++ ++ + Y + V ++G G +
Sbjct: 881 YRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGML-PGLEPFSHYTLNVRVVNGKGEGPA 939
Query: 511 S--ILGNSKHKAPLSGPHINAITEEKGSILISWNSIPVQEQMGCLLHYRIYWKERDSNSQ 568
S + N+ P + + + S+ + W+ P G L Y + ++ +S +
Sbjct: 940 SPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWD--PPSHPNGILTEYTLKYQPINSTHE 997
Query: 569 -PQLCEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAGESSHGNE 612
L ++ ++ + +L Y + A T+AG S E
Sbjct: 998 LGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITE 1042
Score = 35.0 bits (79), Expect = 0.30
Identities = 34/190 (17%), Positives = 79/190 (41%), Gaps = 16/190 (8%)
Query: 385 TVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPP 444
T + T +V+ SA S + PT + ++ P + + ++ ++W P
Sbjct: 615 TCVANTTLDSVSASAVLSVVAPTPTPAPVYDVPNP----PFDLELTDQLDKSVQLSWTPG 670
Query: 445 RKDPSAVQEYVVEWRE-LHPGGDTQVPLNWLRSRPYNVSALISE-NIKSYICYEIRVYAL 502
+ S + ++++E+ + +H G W + + ++ + Y+ Y RV A+
Sbjct: 671 DDNNSPITKFIIEYEDAMHKPG------LWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAV 724
Query: 503 SGDQGGCSSILGN---SKHKAPLSGPH-INAITEEKGSILISWNSIPVQEQMGCLLHYRI 558
+ S +K P P + + E +++I+W + E G L Y++
Sbjct: 725 NSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKV 784
Query: 559 YWKERDSNSQ 568
W+++D + +
Sbjct: 785 SWRQKDGDDE 794
>gi|81158224 neuronal cell adhesion molecule isoform B precursor
[Homo sapiens]
Length = 1183
Score = 64.7 bits (156), Expect = 4e-10
Identities = 61/239 (25%), Positives = 102/239 (42%), Gaps = 24/239 (10%)
Query: 392 NWAVAVSAANSKGSSLPTRINIMNLCEAGL--LAPRQVSANSEGMDNILVTWQPPR--KD 447
N++ V A NS G SLP+ + L +A P V DN+++TW+P +
Sbjct: 700 NYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFES 759
Query: 448 PSAVQEYVVEWRELHPGGDTQVPLNWLRSRPYNVSALISENIKSYICYEIRVYALSGDQG 507
+Y V WR+ GD + W NVS I +++ Y I+V AL+ D G
Sbjct: 760 NGPGLQYKVSWRQ--KDGDDE----WTSVVVANVSKYIVSGTPTFVPYLIKVQALN-DMG 812
Query: 508 GCSS---ILGNSKHKAPLSGP---HINAITEEKGSILISWNSIPVQEQMGCLLHYRIYWK 561
++G+S P+ P +N + + W+ +P++ G L YRIY+
Sbjct: 813 FAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEV--HWDPVPLKSIRGHLQGYRIYYW 870
Query: 562 ERDSNSQPQLCEIPYRV-----SQNSHPINSLQPRVTYVLWMTALTAAGESSHGNEREF 615
+ S+S+ I ++ S+ + L+P Y L + + GE +R F
Sbjct: 871 KTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVF 929
Score = 42.0 bits (97), Expect = 0.002
Identities = 81/427 (18%), Positives = 161/427 (37%), Gaps = 31/427 (7%)
Query: 204 NSLGSSSSLPSTFTFLDIVRPLPPWDIRIKFQKASVSRCTLYWRDEGLVLLNR--LRYRP 261
N+ S S + + +D+ P PP+D+ + Q + + D+ + + + Y
Sbjct: 613 NTTLDSVSASAVLSVVDV--PNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYED 670
Query: 262 SNSR--LWNMVNVTKAKGRHDLLDLKPFTEYEFQISSKLHLYKGSWSDWSESL--RAQTP 317
+ + LW+ L L P+ Y F++ + + K S+ SE +A P
Sbjct: 671 AMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEP 730
Query: 318 EEEPTGMLDVWYMKRHIDYSRQQISLFWKNLSVSEARGKILHYQVTLQELTGGKAMTQNI 377
++ PT + + + + WK L+ E+ G L Y+V+ ++ G T +
Sbjct: 731 DKNPTAV-------EGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTSVV 783
Query: 378 TGHTSWTTV--IPRTGNWAVAVSAANSKGSSLPTRINIMNLC--EAGLLAPRQVSANSEG 433
+ S V P + + V A N G + P +M + ++AP V N
Sbjct: 784 VANVSKYIVSGTPTFVPYLIKVQALNDMGFA-PEPAVVMGHSGEDLPMVAPGNVRVNVVN 842
Query: 434 MDNILVTWQP-PRKD-PSAVQEY-VVEWRELHPG--GDTQVPLNWLRSRPYNVSALISEN 488
V W P P K +Q Y + W+ + L + ++
Sbjct: 843 STLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGML-PG 901
Query: 489 IKSYICYEIRVYALSGDQGGCSS--ILGNSKHKAPLSGPHINAITEEKGSILISWNSIPV 546
++ + Y + V ++G G +S + N+ P + + + S+ + W+ P
Sbjct: 902 LEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWD--PP 959
Query: 547 QEQMGCLLHYRIYWKERDSNSQ-PQLCEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAG 605
G L Y + ++ +S + L ++ ++ + +L Y + A T+AG
Sbjct: 960 SHPNGILTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAG 1019
Query: 606 ESSHGNE 612
S E
Sbjct: 1020 SGSQITE 1026
>gi|4506309 protein tyrosine phosphatase, receptor type, D isoform 1
precursor [Homo sapiens]
Length = 1912
Score = 62.4 bits (150), Expect = 2e-09
Identities = 84/364 (23%), Positives = 157/364 (43%), Gaps = 40/364 (10%)
Query: 257 LRYRPSNSR-LWNMVNVTKAKGRHDLLDLKPFTEYEFQISSKLHLYKGSWSDWSESLRAQ 315
++++P NS L+ ++ A R+ + L P+++YEF++ + ++ +G S E + Q
Sbjct: 356 IQHKPKNSEELYKEIDGV-ATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPS---EPVLTQ 411
Query: 316 TPEEEPTGMLDVWYMKRHID---YSRQQISLFWKNLSVSEARGKILHYQV--TLQELTGG 370
T E+ P+ R + S I + WK E G+I Y+V T+
Sbjct: 412 TSEQAPSSA------PRDVQARMLSSTTILVQWKE--PEEPNGQIQGYRVYYTMDPTQHV 463
Query: 371 KAMTQNITGHTSWTTV---IPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLA-PRQ 426
++ + TT+ +P+ ++V V A S G P +I + + G+ P
Sbjct: 464 NNWMKHNVADSQITTIGNLVPQK-TYSVKVLAFTSIGDG-PLSSDIQVITQTGVPGQPLN 521
Query: 427 VSANSEGMDNILVTWQPPRKDPSAVQEYVVEWRELHPGGDTQVPLNWLRSRPYNVSALIS 486
A E +IL++W PPR D + Y + +++ G + ++ + Y + L
Sbjct: 522 FKAEPESETSILLSWTPPRSD--TIANYELVYKDGEHGEEQRITIE--PGTSYRLQGLKP 577
Query: 487 ENIKSYICYEIRVYALSGDQGGCSS--ILGNSKHKAPLSGPH-INAITEEKGSILISWNS 543
++ Y R+ A S G S+ I + P + P I+ + SIL+SW
Sbjct: 578 NSL-----YYFRLAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQP 632
Query: 544 IPVQEQMGCLLHYRIYWKERDSNSQP--QLCEIPYRVSQNSHPINSLQPRVTYVLWMTAL 601
PV++Q G + Y I + D ++ IP ++ + + L+ Y + +TA
Sbjct: 633 PPVEKQNGIITEYSIKYTAVDGEDDKPHEILGIPSDTTK--YLLEQLEKWTEYRITVTAH 690
Query: 602 TAAG 605
T G
Sbjct: 691 TDVG 694
>gi|18860890 protein tyrosine phosphatase, receptor type, D isoform
2 precursor [Homo sapiens]
Length = 1899
Score = 62.4 bits (150), Expect = 2e-09
Identities = 84/364 (23%), Positives = 157/364 (43%), Gaps = 40/364 (10%)
Query: 257 LRYRPSNSR-LWNMVNVTKAKGRHDLLDLKPFTEYEFQISSKLHLYKGSWSDWSESLRAQ 315
++++P NS L+ ++ A R+ + L P+++YEF++ + ++ +G S E + Q
Sbjct: 343 IQHKPKNSEELYKEIDGV-ATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPS---EPVLTQ 398
Query: 316 TPEEEPTGMLDVWYMKRHID---YSRQQISLFWKNLSVSEARGKILHYQV--TLQELTGG 370
T E+ P+ R + S I + WK E G+I Y+V T+
Sbjct: 399 TSEQAPSSA------PRDVQARMLSSTTILVQWKE--PEEPNGQIQGYRVYYTMDPTQHV 450
Query: 371 KAMTQNITGHTSWTTV---IPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLA-PRQ 426
++ + TT+ +P+ ++V V A S G P +I + + G+ P
Sbjct: 451 NNWMKHNVADSQITTIGNLVPQK-TYSVKVLAFTSIGDG-PLSSDIQVITQTGVPGQPLN 508
Query: 427 VSANSEGMDNILVTWQPPRKDPSAVQEYVVEWRELHPGGDTQVPLNWLRSRPYNVSALIS 486
A E +IL++W PPR D + Y + +++ G + ++ + Y + L
Sbjct: 509 FKAEPESETSILLSWTPPRSD--TIANYELVYKDGEHGEEQRITIE--PGTSYRLQGLKP 564
Query: 487 ENIKSYICYEIRVYALSGDQGGCSS--ILGNSKHKAPLSGPH-INAITEEKGSILISWNS 543
++ Y R+ A S G S+ I + P + P I+ + SIL+SW
Sbjct: 565 NSL-----YYFRLAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQP 619
Query: 544 IPVQEQMGCLLHYRIYWKERDSNSQP--QLCEIPYRVSQNSHPINSLQPRVTYVLWMTAL 601
PV++Q G + Y I + D ++ IP ++ + + L+ Y + +TA
Sbjct: 620 PPVEKQNGIITEYSIKYTAVDGEDDKPHEILGIPSDTTK--YLLEQLEKWTEYRITVTAH 677
Query: 602 TAAG 605
T G
Sbjct: 678 TDVG 681
>gi|18860892 protein tyrosine phosphatase, receptor type, D isoform
3 precursor [Homo sapiens]
Length = 1903
Score = 62.4 bits (150), Expect = 2e-09
Identities = 84/364 (23%), Positives = 157/364 (43%), Gaps = 40/364 (10%)
Query: 257 LRYRPSNSR-LWNMVNVTKAKGRHDLLDLKPFTEYEFQISSKLHLYKGSWSDWSESLRAQ 315
++++P NS L+ ++ A R+ + L P+++YEF++ + ++ +G S E + Q
Sbjct: 356 IQHKPKNSEELYKEIDGV-ATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPS---EPVLTQ 411
Query: 316 TPEEEPTGMLDVWYMKRHID---YSRQQISLFWKNLSVSEARGKILHYQV--TLQELTGG 370
T E+ P+ R + S I + WK E G+I Y+V T+
Sbjct: 412 TSEQAPSSA------PRDVQARMLSSTTILVQWKE--PEEPNGQIQGYRVYYTMDPTQHV 463
Query: 371 KAMTQNITGHTSWTTV---IPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLA-PRQ 426
++ + TT+ +P+ ++V V A S G P +I + + G+ P
Sbjct: 464 NNWMKHNVADSQITTIGNLVPQK-TYSVKVLAFTSIGDG-PLSSDIQVITQTGVPGQPLN 521
Query: 427 VSANSEGMDNILVTWQPPRKDPSAVQEYVVEWRELHPGGDTQVPLNWLRSRPYNVSALIS 486
A E +IL++W PPR D + Y + +++ G + ++ + Y + L
Sbjct: 522 FKAEPESETSILLSWTPPRSD--TIANYELVYKDGEHGEEQRITIE--PGTSYRLQGLKP 577
Query: 487 ENIKSYICYEIRVYALSGDQGGCSS--ILGNSKHKAPLSGPH-INAITEEKGSILISWNS 543
++ Y R+ A S G S+ I + P + P I+ + SIL+SW
Sbjct: 578 NSL-----YYFRLAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQP 632
Query: 544 IPVQEQMGCLLHYRIYWKERDSNSQP--QLCEIPYRVSQNSHPINSLQPRVTYVLWMTAL 601
PV++Q G + Y I + D ++ IP ++ + + L+ Y + +TA
Sbjct: 633 PPVEKQNGIITEYSIKYTAVDGEDDKPHEILGIPSDTTK--YLLEQLEKWTEYRITVTAH 690
Query: 602 TAAG 605
T G
Sbjct: 691 TDVG 694
>gi|93141047 collagen, type XII, alpha 1 long isoform precursor [Homo
sapiens]
Length = 3063
Score = 61.6 bits (148), Expect = 3e-09
Identities = 89/422 (21%), Positives = 169/422 (40%), Gaps = 38/422 (9%)
Query: 187 LTPESPESNFTAKVTAVNSLGSSSSLPSTFTFLDIVRPLPPWDIRIKFQKASVSRCTLYW 246
L+ PE+ + VTA G S L T ++ P ++++ + + T +
Sbjct: 688 LSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGA--PRNLKVTDETTDSFKIT-WT 744
Query: 247 RDEGLVLLNRLRYRPSNSRLWNMVNVTKAKGRHDLLDLKPFTEYEFQISSKLHLYKGSWS 306
+ G VL R+ YRP V + R L +L P T+YE + + + G +
Sbjct: 745 QAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEY--FSGPGT 802
Query: 307 DWSESLRAQTPEEEPTGMLDVWYMKRHIDYSRQQISLFWKNLSVSEARGKILHYQVTLQE 366
+ + + P + R D + + L W S A GK+ Y VT
Sbjct: 803 PLTGNAATEEVRGNPRDL-------RVSDPTTSTMKLSW-----SGAPGKVKQYLVTYTP 850
Query: 367 LTGGKAMTQNITGHTSWTTV--IPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAP 424
+ GG+ + G T+ T + + +A++V+A + G+ L E G +P
Sbjct: 851 VAGGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERG--SP 908
Query: 425 RQVSANSEGMDNILVTWQPPRKDPSAVQEYVVEWRELHPGGDTQVPLNWLRSRPYNVSAL 484
+ + +I W P V+ Y V W+ L+ DT ++ P +
Sbjct: 909 QDLVTKDITDTSIGAYW---TSAPGMVRGYRVSWKSLYDDVDTGE-----KNLPEDAIHT 960
Query: 485 ISENIKSYICYEIRVYALSGDQGGCSSILGNSKHKAPLSGPHINAITEEKGSILISWNSI 544
+ EN++ Y I V+A + G + G++ + + E + ++ ++W
Sbjct: 961 MIENLQPETKYRISVFA-TYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPA 1019
Query: 545 PVQEQMGCLLHYRIYWKERDSNSQPQLCEIPYRVSQNSHPINSLQPRVTYVLWMTALTAA 604
P G +++YR+ ++ Q + ++P V+ S + LQP+ TY + + +
Sbjct: 1020 P-----GKVVNYRVVYRPHGRGKQ-MVAKVPPTVT--STVLKRLQPQTTYDITVLPIYKM 1071
Query: 605 GE 606
GE
Sbjct: 1072 GE 1073
Score = 51.2 bits (121), Expect = 4e-06
Identities = 76/355 (21%), Positives = 135/355 (38%), Gaps = 48/355 (13%)
Query: 260 RPSNSRLWNMVNVTKAKGRHDLLDLKPFTEYEFQISSKLHLYKGSWSDWSESLRAQT-PE 318
RP RL VN + L DL P TEY + + LH + ++R T P
Sbjct: 1517 RPKEVRLGPTVNDMQ------LTDLVPNTEYAVTVQAVLH----DLTSEPVTVREVTLPL 1566
Query: 319 EEPTGMLDVWYMKRHIDYSRQQISLFWKNLSVSEARGKILHYQVTLQELTGGKAMTQNIT 378
P + + D + +++FW+ + + R I+ Y+ +++ +
Sbjct: 1567 PRPQDL-------KLRDVTHSTMNVFWEPVP-GKVRKYIVRYKTPEEDVK--EVEVDRSE 1616
Query: 379 GHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNIL 438
TS + +T + V+VSA + +G S P + AP + +
Sbjct: 1617 TSTSLKDLFSQT-LYTVSVSAVHDEGESPPVTAQETT---RPVPAPTNLKITEVTSEGFR 1672
Query: 439 VTWQPPRKDPSAVQEYVVEWRELHPGGDTQVPLNWLRSRPYNVSALISENIKSYICYEIR 498
TW D S Y + W + LN + + L+ EN+ YE+
Sbjct: 1673 GTWDHGASDVSL---YRITWAPFGSSDKMETILNG------DENTLVFENLNPNTIYEVS 1723
Query: 499 VYALSGDQGGCSSILGNSK------HKAPLSGP-HINAITEEKGSILISWNSIPVQEQMG 551
+ A+ D+ ++G+ + +AP SGP ++ S+ + W+ G
Sbjct: 1724 ITAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWD-----PASG 1778
Query: 552 CLLHYRIYWKERDSNSQPQLCEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAGE 606
+ YRI ++ Q I R QNS + L+P Y + +++L GE
Sbjct: 1779 RVQKYRITYQPSTGEGNEQTTTIGGR--QNSVVLQKLKPDTPYTITVSSLYPDGE 1831
Score = 36.2 bits (82), Expect = 0.13
Identities = 40/165 (24%), Positives = 74/165 (44%), Gaps = 15/165 (9%)
Query: 353 ARGKILHYQVTLQELTGGKAMTQNITGHTSWTTVIPRTG---NWAVAVSAANSKGSSLPT 409
A GK+++Y+V + GK M + T +TV+ R + + V G
Sbjct: 1019 APGKVVNYRVVYRPHGRGKQMVAKVPP-TVTSTVLKRLQPQTTYDITVLPIYKMGEGKLR 1077
Query: 410 RINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKDPSAVQEYVVEWRELHPGGDTQV 469
+ + + +PR + + M + VTW+P P V+ Y V + HP GD +
Sbjct: 1078 QGS--GTTASRFKSPRNLKTSDPTMSSFRVTWEPA---PGEVKGYKVTF---HPTGDDR- 1128
Query: 470 PLNWLRSRPYNVSALISENIKSYICYEIRVYALSGDQGGCSSILG 514
L L PY+ + ++ E +++ Y++ V+ + D G S ++G
Sbjct: 1129 RLGELVVGPYD-NTVVLEELRAGTTYKVNVFGMF-DGGESSPLVG 1171
Score = 30.4 bits (67), Expect = 7.4
Identities = 49/206 (23%), Positives = 84/206 (40%), Gaps = 22/206 (10%)
Query: 256 RLRYRPSNSRLWNMVNVTKAKGRHDLLDLKPFTEYEFQISSKLHLYKGSWSDWSESLRAQ 315
++ Y P + V++ + L DLKP TEY + S + ++SE L+
Sbjct: 1416 KVEYYPVSGGKRQEFYVSRMETSTVLKDLKPETEYVVNVYSVVE------DEYSEPLKG- 1468
Query: 316 TPEEEPTGMLDVWYMKRHIDYSRQQISLFWKNLSVSEARGKILHYQ-VTLQELTGGKAMT 374
T + P ++ + D + + W+ V A G IL Y+ V E T K +
Sbjct: 1469 TEKTLPVPVVSL----NIYDVGPTTMHVQWQ--PVGGATGYILSYKPVKDTEPTRPKEVR 1522
Query: 375 QNIT-GHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEG 433
T T ++P T +AV V A +S P + + L L P+ +
Sbjct: 1523 LGPTVNDMQLTDLVPNT-EYAVTVQAVLHDLTSEPVTVREVTL---PLPRPQDLKLRDVT 1578
Query: 434 MDNILVTWQPPRKDPSAVQEYVVEWR 459
+ V W+P P V++Y+V ++
Sbjct: 1579 HSTMNVFWEPV---PGKVRKYIVRYK 1601
>gi|51093381 leptin receptor isoform 3 [Homo sapiens]
Length = 958
Score = 60.8 bits (146), Expect = 5e-09
Identities = 88/409 (21%), Positives = 159/409 (38%), Gaps = 38/409 (9%)
Query: 105 CINSDEIQICGAEIFVGVAPEQPQNLSCIQKGEQGTVACTWERGRDTHLYTEYTLQLSGP 164
C N E AE++V + N+SC G + C W L E TLQL
Sbjct: 412 CCNEHECHHRYAELYV---IDVNINISCETDGYLTKMTCRWSTSTIQSL-AESTLQLRYH 467
Query: 165 KNLTWQKQCKDIY-------CDYLDFGIN---LTPESPESNFTAKVTAVNSLGSSSSLPS 214
++ + I+ C G P S +T + +SLGS S P+
Sbjct: 468 RSSLYCSDIPSIHPISEPKDCYLQSDGFYECIFQPIFLLSGYTMWIRINHSLGSLDSPPT 527
Query: 215 TFTFLDIVRPLPPWDIRIKFQKASVSRCTLYWRDEGLVLLN---RLRYRPSNSRL-WNMV 270
+V+PLPP ++ + ++ + W N ++RY S + W M
Sbjct: 528 CVLPDSVVKPLPPSSVKAEI-TINIGLLKISWEKPVFPENNLQFQIRYGLSGKEVQWKMY 586
Query: 271 NVTKAKGRHDLLDLKPF-TEYEFQISSKLHLYKGSWSDWSESLRAQTPE-EEPTGMLDVW 328
V AK + L + Y Q+ K G WS+WS + + P + W
Sbjct: 587 EVYDAKSKSVSLPVPDLCAVYAVQVRCKRLDGLGYWSNWSNPAYTVVMDIKVPMRGPEFW 646
Query: 329 YMKRHIDYSRQQ-ISLFWKNLSVSEARGKILHYQVTLQELTGGKAMTQNITGHTSWTTVI 387
+ +++ ++L WK L +++ + Y + G ++++ HT +T +
Sbjct: 647 RIINGDTMKKEKNVTLLWKPLMKNDSLCSVQRYVINHHTSCNG-TWSEDVGNHTKFTFLW 705
Query: 388 PRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKD 447
+ V V A NS G+S+ + + + + +SA ++V+W D
Sbjct: 706 TEQAH-TVTVLAINSIGASVANFNLTFSWPMSKVNIVQSLSAYPLNSSCVIVSWILSPSD 764
Query: 448 PSAVQEYVVEWRELHPGGDTQVPLNWLRSRPYNVSALISENIKSYICYE 496
+ +++EW+ L+ G+ + WLR IS ++K Y ++
Sbjct: 765 -YKLMYFIIEWKNLNEDGE----IKWLR---------ISSSVKKYYIHD 799
>gi|51093379 leptin receptor isoform 2 [Homo sapiens]
Length = 896
Score = 60.8 bits (146), Expect = 5e-09
Identities = 88/409 (21%), Positives = 159/409 (38%), Gaps = 38/409 (9%)
Query: 105 CINSDEIQICGAEIFVGVAPEQPQNLSCIQKGEQGTVACTWERGRDTHLYTEYTLQLSGP 164
C N E AE++V + N+SC G + C W L E TLQL
Sbjct: 412 CCNEHECHHRYAELYV---IDVNINISCETDGYLTKMTCRWSTSTIQSL-AESTLQLRYH 467
Query: 165 KNLTWQKQCKDIY-------CDYLDFGIN---LTPESPESNFTAKVTAVNSLGSSSSLPS 214
++ + I+ C G P S +T + +SLGS S P+
Sbjct: 468 RSSLYCSDIPSIHPISEPKDCYLQSDGFYECIFQPIFLLSGYTMWIRINHSLGSLDSPPT 527
Query: 215 TFTFLDIVRPLPPWDIRIKFQKASVSRCTLYWRDEGLVLLN---RLRYRPSNSRL-WNMV 270
+V+PLPP ++ + ++ + W N ++RY S + W M
Sbjct: 528 CVLPDSVVKPLPPSSVKAEI-TINIGLLKISWEKPVFPENNLQFQIRYGLSGKEVQWKMY 586
Query: 271 NVTKAKGRHDLLDLKPF-TEYEFQISSKLHLYKGSWSDWSESLRAQTPE-EEPTGMLDVW 328
V AK + L + Y Q+ K G WS+WS + + P + W
Sbjct: 587 EVYDAKSKSVSLPVPDLCAVYAVQVRCKRLDGLGYWSNWSNPAYTVVMDIKVPMRGPEFW 646
Query: 329 YMKRHIDYSRQQ-ISLFWKNLSVSEARGKILHYQVTLQELTGGKAMTQNITGHTSWTTVI 387
+ +++ ++L WK L +++ + Y + G ++++ HT +T +
Sbjct: 647 RIINGDTMKKEKNVTLLWKPLMKNDSLCSVQRYVINHHTSCNG-TWSEDVGNHTKFTFLW 705
Query: 388 PRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKD 447
+ V V A NS G+S+ + + + + +SA ++V+W D
Sbjct: 706 TEQAH-TVTVLAINSIGASVANFNLTFSWPMSKVNIVQSLSAYPLNSSCVIVSWILSPSD 764
Query: 448 PSAVQEYVVEWRELHPGGDTQVPLNWLRSRPYNVSALISENIKSYICYE 496
+ +++EW+ L+ G+ + WLR IS ++K Y ++
Sbjct: 765 -YKLMYFIIEWKNLNEDGE----IKWLR---------ISSSVKKYYIHD 799
>gi|40254464 leptin receptor isoform 1 [Homo sapiens]
Length = 1165
Score = 60.8 bits (146), Expect = 5e-09
Identities = 88/409 (21%), Positives = 159/409 (38%), Gaps = 38/409 (9%)
Query: 105 CINSDEIQICGAEIFVGVAPEQPQNLSCIQKGEQGTVACTWERGRDTHLYTEYTLQLSGP 164
C N E AE++V + N+SC G + C W L E TLQL
Sbjct: 412 CCNEHECHHRYAELYV---IDVNINISCETDGYLTKMTCRWSTSTIQSL-AESTLQLRYH 467
Query: 165 KNLTWQKQCKDIY-------CDYLDFGIN---LTPESPESNFTAKVTAVNSLGSSSSLPS 214
++ + I+ C G P S +T + +SLGS S P+
Sbjct: 468 RSSLYCSDIPSIHPISEPKDCYLQSDGFYECIFQPIFLLSGYTMWIRINHSLGSLDSPPT 527
Query: 215 TFTFLDIVRPLPPWDIRIKFQKASVSRCTLYWRDEGLVLLN---RLRYRPSNSRL-WNMV 270
+V+PLPP ++ + ++ + W N ++RY S + W M
Sbjct: 528 CVLPDSVVKPLPPSSVKAEI-TINIGLLKISWEKPVFPENNLQFQIRYGLSGKEVQWKMY 586
Query: 271 NVTKAKGRHDLLDLKPF-TEYEFQISSKLHLYKGSWSDWSESLRAQTPE-EEPTGMLDVW 328
V AK + L + Y Q+ K G WS+WS + + P + W
Sbjct: 587 EVYDAKSKSVSLPVPDLCAVYAVQVRCKRLDGLGYWSNWSNPAYTVVMDIKVPMRGPEFW 646
Query: 329 YMKRHIDYSRQQ-ISLFWKNLSVSEARGKILHYQVTLQELTGGKAMTQNITGHTSWTTVI 387
+ +++ ++L WK L +++ + Y + G ++++ HT +T +
Sbjct: 647 RIINGDTMKKEKNVTLLWKPLMKNDSLCSVQRYVINHHTSCNG-TWSEDVGNHTKFTFLW 705
Query: 388 PRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKD 447
+ V V A NS G+S+ + + + + +SA ++V+W D
Sbjct: 706 TEQAH-TVTVLAINSIGASVANFNLTFSWPMSKVNIVQSLSAYPLNSSCVIVSWILSPSD 764
Query: 448 PSAVQEYVVEWRELHPGGDTQVPLNWLRSRPYNVSALISENIKSYICYE 496
+ +++EW+ L+ G+ + WLR IS ++K Y ++
Sbjct: 765 -YKLMYFIIEWKNLNEDGE----IKWLR---------ISSSVKKYYIHD 799
>gi|20127422 Down syndrome cell adhesion molecule isoform CHD2-42
precursor [Homo sapiens]
Length = 2012
Score = 59.7 bits (143), Expect = 1e-08
Identities = 107/507 (21%), Positives = 192/507 (37%), Gaps = 48/507 (9%)
Query: 129 NLSCIQKGEQGTVACTWERGRDTHLYTEYTLQLSGPKNLTWQKQCKDIYCDYLDFGINLT 188
N + +G++ ++CT + + E ++ P+ + K++ + + + +
Sbjct: 795 NTTLATQGQKKEMSCTAHGEKPIIVRWEKEDRIINPEMARYLVSTKEVGEEVIST-LQIL 853
Query: 189 PESPESNFTAKVTAVNSLGSSSSLPSTFTFLDIVRPLPPWDIRIKFQKASVSRCTLYWR- 247
P E + A+NS G + L + P P +I IK KA TL W
Sbjct: 854 PTVREDSGFFSCHAINSYGEDRGIIQ----LTVQEPPDPPEIEIKDVKART--ITLRWTM 907
Query: 248 --DEGLVLLNRLRYRPSNSRLWNMVNVTKAKGRH----DLLDLKPFTEYEFQISSKLHLY 301
D + + S W+ TK ++D+ P + Y ++ +K +
Sbjct: 908 GFDGNSPITGYDIECKNKSDSWDSAQRTKDVSPQLNSATIIDIHPSSTYSIRMYAKNRIG 967
Query: 302 KGSWSDWSESLRAQTPEEEPTGMLDVWYMKRHIDYSRQQISLFWKNLSVSEARGKILHYQ 361
K S+ S L E P G +++ S Q I + WK G I YQ
Sbjct: 968 K---SEPSNELTITADEAAPDGPPQEVHLE---PISSQSIRVTWKAPKKHLQNGIIRGYQ 1021
Query: 362 VTLQEL-TGGKAMTQNITGHTSWTTVIPRTGN------WAVAVSAANSKGSSLPTR-INI 413
+ +E TGG I+ TS + + N + + V A N G+ ++ I
Sbjct: 1022 IGYREYSTGGNFQFNIISVDTSGDSEVYTLDNLNKFTQYGLVVQACNRAGTGPSSQEIIT 1081
Query: 414 MNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKDP--SAVQEY-VVEWRELHPGGDTQVP 470
L + P V A + ++I ++W K+ +Q + V+ W L G
Sbjct: 1082 TTLEDVPSYPPENVQAIATSPESISISWSTLSKEALNGILQGFRVIYWANLMDG-----E 1136
Query: 471 LNWLRSRPYNVSALISENIKSYICYEIRVYALS--GDQGGCSSILGNSKHKAPLSGPHIN 528
L +++ +L + ++ Y Y I+V A + GD I +K P +
Sbjct: 1137 LGEIKNITTTQPSLELDGLEKYTNYSIQVLAFTRAGDGVRSEQIFTRTKEDVPGPPAGVK 1196
Query: 529 AITEEKGSILISWNSIPVQEQMGCLLHYRIYWKERDSNSQPQ-LCEIPYRVSQNSHPINS 587
A + +SW +P + G + Y ++ S+ P + E S+ I +
Sbjct: 1197 AAAASASMVFVSW--LPPLKLNGIIRKYTVFC----SHPYPTVISEFEASPDSFSYRIPN 1250
Query: 588 LQPRVTYVLWMTALTAAGESSHGNERE 614
L Y +W+ A+T+AG GN E
Sbjct: 1251 LSRNRQYSVWVVAVTSAG---RGNSSE 1274
Score = 32.7 bits (73), Expect = 1.5
Identities = 29/107 (27%), Positives = 51/107 (47%), Gaps = 7/107 (6%)
Query: 219 LDIVRPLPPWDIRIKFQKASVSRCTLYWR--DEGLVLLNR--LRYRPSNSRLWNMVNVTK 274
L++ +PP R+ K + S TL W D G + L+Y NS W ++
Sbjct: 1372 LNLQVQVPPDQPRLTVSKTTSSSITLSWLPGDNGGSSIRGYILQYSEDNSEQWGSFPISP 1431
Query: 275 AKGRHDLLDLKPFTEYEFQISSKLHLYKGSWSDWSESLRAQTPEEEP 321
++ + L +LK T Y+F ++++ + G SE + A+T +EP
Sbjct: 1432 SERSYRLENLKCGTWYKFTLTAQNGVGPGR---ISEIIEAKTLGKEP 1475
Score = 30.4 bits (67), Expect = 7.4
Identities = 16/50 (32%), Positives = 23/50 (46%), Gaps = 1/50 (2%)
Query: 246 WRDEGLVLLN-RLRYRPSNSRLWNMVNVTKAKGRHDLLDLKPFTEYEFQI 294
W D G + + L YRP + +W T + L DL+ T YE Q+
Sbjct: 1499 WNDGGCPITSFTLEYRPFGTTVWTTAQRTSLSKSYILYDLQEATWYELQM 1548
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 56.2 bits (134), Expect = 1e-07
Identities = 73/311 (23%), Positives = 133/311 (42%), Gaps = 24/311 (7%)
Query: 200 VTAVNSLGSSSSLPSTFTFLDIVRPLPPWDIRIKFQKASVSRCTLYWRDE----GLVLLN 255
VTA NS G+++ + + + +P PP ++F + S + W G + N
Sbjct: 24384 VTATNSAGTATE---NLSVIVLEKPGPPVG-PVRFDEVSADFVVISWEPPAYTGGCQISN 24439
Query: 256 RL-RYRPSNSRLWNMVNVTKAKGRHDLLDLKPFTEYEFQISSKLHLYKGSWSDWSESLRA 314
+ R + + W+MV+ T A+ + LK TEY+F+I ++ K + D S+++
Sbjct: 24440 YIVEKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAPLD-SKAVIV 24498
Query: 315 QTPEEEPTGMLDVWYMKRHIDYSRQQISLFWKNLSVSEARGKILHYQVTLQE---LTGGK 371
Q P +EP G ++ S+ Q+ + W V++ KI+ Y + +E + K
Sbjct: 24499 QYPFKEP-GPPGTPFV---TSISKDQMLVQWHE-PVNDGGTKIIGYHLEQKEKNSILWVK 24553
Query: 372 AMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANS 431
I TT + + VSA N G P++++ + P + A
Sbjct: 24554 LNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAIV 24613
Query: 432 EGMDNILVTWQPPRKD-PSAVQEYVVEWRELHPGGDTQVPLNWLRSRPYNVSALISENIK 490
+N+ + W+ P D S + Y+VE ++L G + + + VS L+ +
Sbjct: 24614 ITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQ-- 24671
Query: 491 SYICYEIRVYA 501
YE RV A
Sbjct: 24672 ---RYEFRVIA 24679
Score = 52.0 bits (123), Expect = 2e-06
Identities = 77/334 (23%), Positives = 133/334 (39%), Gaps = 27/334 (8%)
Query: 183 FGINLTPESPESNFTAKVTAVNS---LGSSSSLPSTFTFLDIV---RPLPPWDIRIKFQK 236
F +T E+ N VTA + +++S +T F++IV RP PP +
Sbjct: 26523 FNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTG-PVVISD 26581
Query: 237 ASVSRCTLYWR----DEGLVLLNR-LRYRPSNSRLWNMVNVTKAKGRHDLLDLKPFTEYE 291
+ TL W D G + N L R +++ +W V+ T A+ ++ L EY+
Sbjct: 26582 ITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQ 26641
Query: 292 FQISSKLHLYKGSWSDWSESLRAQTPEEEPTGMLDVWYMKRHIDYSRQQISLFWKNLSVS 351
F+I ++ D S + + P P W + +R+ I++ W VS
Sbjct: 26642 FRIKAENRFGISDHID-SACVTVKLPYTTPGPPSTPWV----TNVTRESITVGWHE-PVS 26695
Query: 352 EARGKILHYQVTLQE---LTGGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLP 408
++ Y + +++ + KA I T I + V A N+ G P
Sbjct: 26696 NGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGVGKP 26755
Query: 409 TRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKD-PSAVQEYVVEWRELHPGGDT 467
+ + L PR V +++ ++WQ P D S + Y+VE R+L G T
Sbjct: 26756 SHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWT 26815
Query: 468 QVPLNWLRSRPYNVSALISENIKSYICYEIRVYA 501
+ + + +S L + YE RV+A
Sbjct: 26816 KASFTNVTETQFIISGLTQNS-----QYEFRVFA 26844
Score = 48.5 bits (114), Expect = 3e-05
Identities = 69/312 (22%), Positives = 130/312 (41%), Gaps = 29/312 (9%)
Query: 203 VNSLGSSSSLPSTFTFLDIVRPLPPWDIRIKFQKASVSRCTLYWR----DEGLVLLNRL- 257
V S+ T + + +P PP +K + + TL W D G + N +
Sbjct: 22220 VKLTNSAGEAIETLNVIVLDKPGPPTG-PVKMDEVTADSITLSWGPPKYDGGSSINNYIV 22278
Query: 258 RYRPSNSRLWNMVNVTKAKGRHDLLDLKPFTEYEFQISSKLHLYKGSWSDWSESLRAQTP 317
R +++ W +V+ T A+ LK EY+F+I+++ K ++ + SE AQ P
Sbjct: 22279 EKRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGKSTYLN-SEPTVAQYP 22337
Query: 318 EEEP----TGMLDVWYMKRHIDYSRQQISLFWKNLSVSEARGKILHYQVTLQELTGGKAM 373
+ P T ++ + SR + + W N +S+ +++ Y + +E +
Sbjct: 22338 FKVPGPPGTPVVTL--------SSRDSMEVQW-NEPISDGGSRVIGYHLERKERNSILWV 22388
Query: 374 TQNIT--GHTSW-TTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSAN 430
N T T + TT + + VSA N G P++++ + P + A
Sbjct: 22389 KLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAI 22448
Query: 431 SEGMDNILVTWQPPRKD-PSAVQEYVVEWRELHPGGDTQVPLNWLRSRPYNVSALISENI 489
+++ + W+ P D S + Y+VE +EL G + + + V+ L+ ++
Sbjct: 22449 IVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDH- 22507
Query: 490 KSYICYEIRVYA 501
YE RV A
Sbjct: 22508 ----RYEFRVIA 22515
Score = 46.2 bits (108), Expect = 1e-04
Identities = 76/334 (22%), Positives = 137/334 (41%), Gaps = 41/334 (12%)
Query: 185 INLTPESPESNFTAKVTAVNSLGSSSSLPSTFTFLDIVRPLPPWDIRIKFQKASVSRCTL 244
+++ S E T ++ NS GS + +P T LD RP PP IRI + S T+
Sbjct: 25452 LSIKEASKEDVGTYELCVSNSAGSIT-VPITIIVLD--RPGPPGPIRI--DEVSCDSITI 25506
Query: 245 YWR----DEGLVLLNRL-RYRPSNSRLWNMVNVTKAKGRHDLLDLKPFTEYEFQISSKLH 299
W D G + N + + + S W++V+ A+ ++ L +EY+F++ ++
Sbjct: 25507 SWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENR 25566
Query: 300 LYKGSWSDWSESLRAQTP--EEEPTGMLDVWYMKRHIDYSRQQISLFWKNLSVSEARGKI 357
K S+S+ S ++ A+ P P G V + ++ + + W+ + V++ ++
Sbjct: 25567 YGKSSYSE-SSAVVAEYPFSPPGPPGTPKV------VHATKSTMLVTWQ-VPVNDGGSRV 25618
Query: 358 LHYQVTLQE---LTGGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKG----SSLPTR 410
+ Y + +E + KA I + + + V A N G S
Sbjct: 25619 IGYHLEYKERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEP 25678
Query: 411 INIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKDPSA-VQEYVVEWRELHPGGDTQV 469
+ + C+ P Q + ++ + W P D A + Y+VE REL G
Sbjct: 25679 VPARDPCD----PPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDG----- 25729
Query: 470 PLNWLRSRPYNVSALISE--NIKSYICYEIRVYA 501
WL+ N+ E + YE RV+A
Sbjct: 25730 --RWLKCNYTNIQETYFEVTELTEDQRYEFRVFA 25761
Score = 42.4 bits (98), Expect = 0.002
Identities = 34/127 (26%), Positives = 64/127 (50%), Gaps = 10/127 (7%)
Query: 200 VTAVNSLGSSSSLPSTFTFLDIVRPLPPWDIRIKFQKASVSRCTLYWRDE----GLVLLN 255
+T N +G ++ + + + +P PP +KF S TL W G + N
Sbjct: 23302 ITVANVVGQKTA---SIEIVTLDKPDPPKG-PVKFDDVSAESITLSWNPPLYTGGCQITN 23357
Query: 256 RL-RYRPSNSRLWNMVNVTKAKGRHDLLDLKPFTEYEFQISSKLHLYKGSWSDWSESLRA 314
+ + R + + +W++V+ T A+ + LK TEY+F+I ++ + Y S++ S+ + A
Sbjct: 23358 YIVQKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFAE-NRYGQSFALESDPIVA 23416
Query: 315 QTPEEEP 321
Q P +EP
Sbjct: 23417 QYPYKEP 23423
Score = 40.8 bits (94), Expect = 0.005
Identities = 56/231 (24%), Positives = 103/231 (44%), Gaps = 19/231 (8%)
Query: 200 VTAVNSLGSSSSLPSTFTFLDIVRPLPPWDIRIKFQKASVSRCTLYWR----DEGLVLLN 255
+T NS GS S+ + LD P PP D+++K + + + TL W D G + N
Sbjct: 21931 LTVENSSGSKSAFVNV-RVLDT--PGPPQDLKVK--EVTKTSVTLTWDPPLLDGGSKIKN 21985
Query: 256 RL-RYRPSNSRLWNMVNVTKAKGRHDLLDLKPFTEYEFQISSKLHLYKGSWSDWSESLRA 314
+ R S + ++ V K + L+ Y F++ ++ G ++ +ES++A
Sbjct: 21986 YIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKA 22045
Query: 315 QTPEEEPTGMLDVWYMKRHIDYSRQQISLFWKNLSVSEARGKILHYQVTLQELTGGKAMT 374
+ P G + + +D +R +SL W+ + +IL Y V +Q K T
Sbjct: 22046 -SERPLPPGKITL------MDVTRNSVSLSWEKPE-HDGGSRILGYIVEMQTKGSDKWAT 22097
Query: 375 QNITGHTSWT-TVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAP 424
T T T + + ++ VSA N KG S P ++++ + + ++ P
Sbjct: 22098 CATVKVTEATITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKDLVIPP 22148
Score = 39.7 bits (91), Expect = 0.012
Identities = 81/353 (22%), Positives = 136/353 (38%), Gaps = 33/353 (9%)
Query: 127 PQNLSCIQKGEQGTVACTWER-----GRDTHLYTEYTLQLSGPKNLTWQKQCKDIYCDYL 181
P + + K + ++ W R G D + Y L+ K+L W K K+ D
Sbjct: 27068 PPGIPEVTKITKNSMTVVWSRPIADGGSDI---SGYFLEKRDKKSLGWFKVLKETIRDTR 27124
Query: 182 DFGINLTPESPESNFTAKVTAVNSLGSSS-SLPSTFTFL--DIVRPLPPWDIRIKFQKAS 238
LT S ++ +V AVN+ G S PS F I P PP IRI ++
Sbjct: 27125 QKVTGLTENS---DYQYRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIA--DST 27179
Query: 239 VSRCTLYWR----DEGLVLLNRL-RYRPSNSRLWNMVNVTKAKGR---HDLLDLKPFTEY 290
S TL W D G + + R W V+ TK + R + + +LKP Y
Sbjct: 27180 KSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVS-TKGEVRTTEYVVSNLKPGVNY 27238
Query: 291 EFQISSKLHLYKGSWSDWSESLRAQTPEEEPTGMLDVWYMKRHIDYSRQQISLFWKNLSV 350
F++S+ +G + +E ++A+ E P LDV I + + + + +
Sbjct: 27239 YFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQVL---IPF 27295
Query: 351 SEARGKILHYQVTLQELTGGKAMTQNITGHTSWTTV--IPRTGNWAVAVSAANSKGSSLP 408
+ ++ + L + T +S T+ + R ++ N G
Sbjct: 27296 KGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKS 27355
Query: 409 TRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKD-PSAVQEYVVEWRE 460
+ +++ L QV S G + + W PP D S + YV+E R+
Sbjct: 27356 STVSVKVLDTPAACQKLQVKHVSRG--TVTLLWDPPLIDGGSPIINYVIEKRD 27406
Score = 38.1 bits (87), Expect = 0.035
Identities = 74/344 (21%), Positives = 116/344 (33%), Gaps = 53/344 (15%)
Query: 182 DFGINLTPESPESNFTAKVTAVNSLGSSSSLPSTFTFLDIVRPLPPWDIRIKFQKASVSR 241
+F + E+ E F +G + L +I+ P P D+ +K + R
Sbjct: 18561 EFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEP-PEIDLDASMRKLVIVR 18619
Query: 242 CTLYWRDEGLVLLNRLRYRPSNSRLWNMVNVTKA--KGRHDLLDLKPFTEYEFQISSKLH 299
R L +R RP+ W V + KG+ DL+D F
Sbjct: 18620 AGCPIR-----LFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMAFL----------- 18663
Query: 300 LYKGSWSDWSESLRAQTPEEEPTGMLDVWYMKRHIDYSRQQISLFWKNLSVSEARGKILH 359
+ S D +S + P G V+ R +D +L VS+ H
Sbjct: 18664 VIPNSTRD--DSGKYSLTLVNPAGEKAVFVNVRVLDTPGPV-----SDLKVSDVTKTSCH 18716
Query: 360 YQVTLQELTGGKAMTQNIT-----GHTSWTTVIPRT------------GN-WAVAVSAAN 401
E GG +T I +W+TV P GN + V+A N
Sbjct: 18717 VSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVN 18776
Query: 402 SKGSSLPTRINIMNLCEAGLLAP---RQVSANSEGMDNILVTWQPPRKDPSA-VQEYVVE 457
G +PT + L L P R++ ++ + W PP +D A + Y+
Sbjct: 18777 EYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITS 18836
Query: 458 WRELHPGGDTQVPLNWLRSRPYNVSALISENIKSYICYEIRVYA 501
+RE D W +L+ +K Y+ RV A
Sbjct: 18837 YREEEQPAD-----RWTEYSVVKDLSLVVTGLKEGKKYKFRVAA 18875
Score = 37.7 bits (86), Expect = 0.046
Identities = 43/183 (23%), Positives = 74/183 (40%), Gaps = 18/183 (9%)
Query: 124 PEQPQNLSCIQKGEQGTVACTWERGRDT--HLYTEYTLQLSGPKNLTWQKQCKDIYCDYL 181
PE P N + + +V+ +W R +D T Y ++ W + K +
Sbjct: 30329 PEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTM 30388
Query: 182 DFGINLTPESPESNFTAKVTAVNSLGSSSSLPSTFTFL---DIVRPLPPWDIRI-KFQKA 237
+T P++ + ++ A N +G S + P++ + +P P ++ I K
Sbjct: 30389 ---YTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKD 30445
Query: 238 SVSRCTLYWR----DEGLVLLNR-LRYRPSNSRLWNMVNVTKAKGRHDLL-DLKPFTEYE 291
SV TL W D G +L + YR S W N + K + + L TEYE
Sbjct: 30446 SV---TLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYE 30502
Query: 292 FQI 294
F++
Sbjct: 30503 FRV 30505
Score = 37.4 bits (85), Expect = 0.060
Identities = 90/379 (23%), Positives = 149/379 (39%), Gaps = 44/379 (11%)
Query: 196 FTAKVTAVNSLGSSSSLPSTFTFL---DIVRPLPP-WDIRIKFQKASVS-RCTLYWRDEG 250
++ +V AVN G S + L + P PP W I K + + T+ +D G
Sbjct: 14053 YSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGG 14112
Query: 251 LVLLNRL-RYRPSNSRLWNMVNVTKAKGRHDLLDLKPFTEYEFQISSKLHLYKGSWSDWS 309
+ N + R + W V+ T + + L + Y F+++++ + + +++
Sbjct: 14113 SPITNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIE 14172
Query: 310 ESLRAQ---TPEEEPTGMLDVWYMKRHIDYSRQQISLFWKNLSVSEARGKILHYQVTLQE 366
+S+ A+ T P + V KRH+D L W+ R I Y + +E
Sbjct: 14173 DSVLAKDTFTTPGPPYALAVVDVTKRHVD-------LKWEPPKNDGGR-PIQRYVIEKKE 14224
Query: 367 LTGGKAMTQNITGHTSW----TTVIPRTGNWAVAVSAANSKG---SSLPTRINIMNLCEA 419
G + + T T VI T V A N G S PT I + +
Sbjct: 14225 RLGTRWVKAGKTAGPDCNFRVTDVIEGT-EVQFQVRAENEAGVGHPSEPTEILSIEDPTS 14283
Query: 420 GLLAPRQVSANSEGMDNILVTWQPPRKD-PSAVQEYVVEWRELHPGGDTQVPLNWLR--S 476
P + G +I + W+PP K+ S + Y V E+ P G + W+R S
Sbjct: 14284 PPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHV---EMCPVGTEK----WMRVNS 14336
Query: 477 RPY-NVSALISENIKSYICYEIRVYALSG-DQGGCSSILGNSKHKAPLSGPHIN------ 528
RP ++ + E + Y +RV A++ S I N K P P I+
Sbjct: 14337 RPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHDI 14396
Query: 529 -AITEEKGSILISWNSIPV 546
I EK SI + + ++PV
Sbjct: 14397 IVIEGEKLSIPVPFRAVPV 14415
Score = 36.6 bits (83), Expect = 0.10
Identities = 59/287 (20%), Positives = 108/287 (37%), Gaps = 25/287 (8%)
Query: 335 DYSRQQISLFWKNLSVSEARGKILHYQVTLQELTGGKAMTQNITGHTSWTTV----IPRT 390
+ ++ + + WK + + KI +Y + +E+ GK + +T ++ TT +
Sbjct: 16923 EVTKDYMVISWKP-PLDDGGSKITNYIIEKKEV--GKDVWMPVTSASAKTTCKVSKLLEG 16979
Query: 391 GNWAVAVSAANSKGSSLPTRINIMNLCEAGLL--APRQVSANSEGMDNILVTWQPPRKDP 448
++ + A N G S P + M + + AP Q D+ LVTW P
Sbjct: 16980 KDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGG 17039
Query: 449 SAVQEYVVEWRELHPGGDTQVPLNWLRSRPYNVSALISENIKSYI--C-YEIRVYALS-- 503
+ Y++E RE + W R + + + C YE RV A +
Sbjct: 17040 KPITNYILEKRE-------TMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEI 17092
Query: 504 --GDQGGCSS-ILGNSKHKAPLSGPHINAITEEKGSILISWNSIPVQEQMGCLLHYRIYW 560
GD S + P + AI S+ ++W P + +L Y + +
Sbjct: 17093 GIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQP-PRHDGGSKILGYIVEY 17151
Query: 561 KERDSNSQPQLCEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAGES 607
++ + P + + + L+ TY + A+ AAGES
Sbjct: 17152 QKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGES 17198
Score = 36.6 bits (83), Expect = 0.10
Identities = 52/217 (23%), Positives = 91/217 (41%), Gaps = 23/217 (10%)
Query: 397 VSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKD-PSAVQEYV 455
++A NS GS T I + L + G P V N D +++W+PP +D S + Y+
Sbjct: 19368 ITAENSSGSKSAT-IKLKVLDKPG--PPASVKINKMYSDRAMLSWEPPLEDGGSEITNYI 19424
Query: 456 VEWRELHPGGDTQVPLNWLR-SRPYNVSALISENIKSYICYEIRVYALS----GDQGGCS 510
V+ RE T P NW + S +++ E + Y+ R+ A + GD
Sbjct: 19425 VDKRE------TSRP-NWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTE 19477
Query: 511 SILGNSKHKAP--LSGPHINAITEEKGSILISWNSIPVQEQMGCLLHYRIYWKERDSNSQ 568
+ + + P P I+ IT K + +SW P + + Y + +E + +
Sbjct: 19478 PAIAKNPYDPPGRCDPPVISNIT--KDHMTVSWKP-PADDGGSPITGYLLEKRETQAVNW 19534
Query: 569 PQLCEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAG 605
++ P + + + LQ Y +TA+ AG
Sbjct: 19535 TKVNRKP--IIERTLKATGLQEGTEYEFRVTAINKAG 19569
Score = 36.6 bits (83), Expect = 0.10
Identities = 41/176 (23%), Positives = 71/176 (40%), Gaps = 9/176 (5%)
Query: 391 GNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKDPSA 450
G + + VS NS GS + I I+ L G P + + D+I ++W PP D
Sbjct: 25463 GTYELCVS--NSAGS-ITVPITIIVLDRPG--PPGPIRIDEVSCDSITISWNPPEYDGGC 25517
Query: 451 -VQEYVVEWRELHPGGDTQVPLNWLRSRPYNVSALISENIKSYICYEIRVYALSGDQGGC 509
+ Y+VE +E V R+ V + +C E R S +
Sbjct: 25518 QISNYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSES-- 25575
Query: 510 SSILGNSKHKAPLSGPHINAITEEKGSILISWNSIPVQEQMGCLLHYRIYWKERDS 565
S+++ P + K ++L++W +PV + ++ Y + +KER S
Sbjct: 25576 SAVVAEYPFSPPGPPGTPKVVHATKSTMLVTW-QVPVNDGGSRVIGYHLEYKERSS 25630
Score = 36.6 bits (83), Expect = 0.10
Identities = 68/306 (22%), Positives = 116/306 (37%), Gaps = 59/306 (19%)
Query: 164 PKNLTWQKQCKDIYCDY------LDFGINLTPESPESNFTAK--VTAVNSLGSSSSLPST 215
P +TW+K K++ D D LT N T K +T N +G S +
Sbjct: 27300 PPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVS 27359
Query: 216 FTFLDIVRPLPPWDIRIKFQKASVSRCTLYWR----DEGLVLLNR-LRYRPSNSRLWNMV 270
LD P +++ + S TL W D G ++N + R + R W++V
Sbjct: 27360 VKVLDT----PAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVV 27415
Query: 271 NVTKAKGRHDLLDLKPFTEYEFQISSKLHLYKGSWSDWSESLRAQTPEEEPTGMLDVWYM 330
+ + L+DL T + F++ ++ + G + +E ++A E P + D+ M
Sbjct: 27416 SHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKA---AEVPAPIRDL-SM 27471
Query: 331 KRHIDYSRQQISLFWKNLSVSEARGKILHYQVTLQELTGGKAMTQNITGHTSWTTVIPRT 390
K D ++ + L W T + GG +T+ V+ R
Sbjct: 27472 K---DSTKTSVILSW-----------------TKPDFDGGSVITE---------YVVERK 27502
Query: 391 GNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKDPSA 450
G S A G S I + L E +L R + N +G+ + P P
Sbjct: 27503 GKGEQTWSHA---GISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSD------PVTIGPIT 27553
Query: 451 VQEYVV 456
V+E ++
Sbjct: 27554 VKELII 27559
Score = 36.2 bits (82), Expect = 0.13
Identities = 76/327 (23%), Positives = 120/327 (36%), Gaps = 50/327 (15%)
Query: 164 PKNLTWQKQCKDIYCDYLDFGINLTPESPESNFTAK-----------VTAVNSLGSSSSL 212
PK+ +W K KDI + I TP S S T K +TA N G+
Sbjct: 20409 PKS-SWSKAGKDIRPSDIT-QITSTPTS--SMLTIKYATRKDAGEYTITATNPFGTKVEH 20464
Query: 213 PSTFTFLDIVRPLPPWDIRIKFQKASVSRCTLYW----RDEGLVLLNRLRYRPSNSRL-W 267
T LD+ P PP + I S + TL W D G + + + + SRL W
Sbjct: 20465 VKV-TVLDV--PGPPGPVEIS--NVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLW 20519
Query: 268 NMVNVTKAKGRHDLLDLKPFTEYEFQISSKLHLYKGSWSDWSESLRAQTPEEEPTGMLDV 327
+V+ RH L EY F++S+ H KG + + EP M+D
Sbjct: 20520 TVVSEDIQSCRHVATKLIQGNEYIFRVSAVNHYGKG-----------EPVQSEPVKMVDR 20568
Query: 328 W------YMKRHIDYSRQQISLFWKNLSVSEARGKILHYQVTLQE---LTGGKAMTQNIT 378
+ + ++ ++ WK V + +I Y V +E L +A+ ++
Sbjct: 20569 FGPPGPPEKPEVSNVTKNTATVSWKR-PVDDGGSEITGYHVERREKKSLRWVRAIKTPVS 20627
Query: 379 GHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVS---ANSEGMD 435
T + + VSA N G P+ + L + P S
Sbjct: 20628 DLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKK 20687
Query: 436 NILVTWQPPRKDPS-AVQEYVVEWREL 461
+ + W P D + YVVE +++
Sbjct: 20688 SASLAWGKPHYDGGLEITGYVVEHQKV 20714
Score = 35.8 bits (81), Expect = 0.18
Identities = 42/195 (21%), Positives = 85/195 (43%), Gaps = 21/195 (10%)
Query: 289 EYEFQISSKLHLYKGSWSDWSESLRAQTPEEEPTGMLDVWYMKRHIDYSRQQISLFWKNL 348
EY F++S++ + G + + A++ + P L+V D +R +SL W+
Sbjct: 13159 EYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTIT----DVNRFGVSLTWEPP 13214
Query: 349 SVSEARGKILHYQVTLQELTGGK---AMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGS 405
+ +I +Y + L++ T + AMT ++ T + ++ V A N G
Sbjct: 13215 EY-DGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGV 13273
Query: 406 SLPTR----INIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKD-PSAVQEYVVEWRE 460
P+ + + + E P ++++ + ++ + W+PP KD S + Y++E
Sbjct: 13274 GKPSAATPFVKVADPIERPS-PPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYIIE--R 13330
Query: 461 LHPGGDTQVPLNWLR 475
G D NW+R
Sbjct: 13331 CEEGKD-----NWIR 13340
Score = 35.8 bits (81), Expect = 0.18
Identities = 62/283 (21%), Positives = 112/283 (39%), Gaps = 28/283 (9%)
Query: 339 QQISLFWKNLSVSEARGKILHYQVTLQELTG--GKAMTQNITGHTSWTTVIPRTGNWAVA 396
++I+L W+ + KI HY V +E + +++++ TT I + +
Sbjct: 26981 EKITLLWRP-PADDGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFR 27039
Query: 397 VSAANSKGSSLPTRINIMNLCEA-------GLLAPRQVSANSEGMDNILVTWQPPRKDP- 448
V A N G P + + A G+ +++ NS + V W P D
Sbjct: 27040 VRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNS-----MTVVWSRPIADGG 27094
Query: 449 SAVQEYVVEWRELHPGGDTQVPLNWLRSRPYNVSALISENIKSYICYEIRVYALSG-DQG 507
S + Y +E R+ G +V +R V+ L +EN Y+ RV A++ QG
Sbjct: 27095 SDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGL-TENSD----YQYRVCAVNAAGQG 27149
Query: 508 GCSSILGNSKHKAPLSGP----HINAITEEKGSILISWNSIPVQEQMGCLLHYRIYWKER 563
S K P+ P I K SI + W+ PV + + Y + ++
Sbjct: 27150 PFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSK-PVYDGGSAVTGYVVEIRQG 27208
Query: 564 DSNSQPQLCEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAGE 606
+ + V + +++L+P V Y ++A+ AG+
Sbjct: 27209 EEEEWTTV-STKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQ 27250
Score = 35.8 bits (81), Expect = 0.18
Identities = 53/246 (21%), Positives = 98/246 (39%), Gaps = 18/246 (7%)
Query: 369 GGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAP---R 425
G +++++T T T + + V+A N G + ++ C + + P
Sbjct: 29878 GWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIGSYLQSEVIE-CRSSIRIPGPPE 29936
Query: 426 QVSANSEGMDNILVTWQPPRKD-PSAVQEYVVEWRELHPGGDTQVPLNWLRSRPYNVSAL 484
+ D + +TW PP D S V Y+VE +E+ D V +N + P ++
Sbjct: 29937 TLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVR--ADRWVRVNKV---PVTMTRY 29991
Query: 485 ISENIKSYICYEIRVYAL----SGDQGGCSSILGNSKHKAPLSGPHINAITE-EKGSILI 539
S + + YE RV A+ SG S + AP P +T+ + S+ +
Sbjct: 29992 RSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSL 30051
Query: 540 SWNSIPVQEQMGCLLHYRIYWKERDSNSQPQLCEIPYRVSQNSHPINSLQPRVTYVLWMT 599
+W S+P E + Y I ++ D + + P ++ + + + L Y +
Sbjct: 30052 AW-SVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIRE--YTLTHLPQGAEYRFRVL 30108
Query: 600 ALTAAG 605
A A G
Sbjct: 30109 ACNAGG 30114
Score = 35.4 bits (80), Expect = 0.23
Identities = 46/192 (23%), Positives = 83/192 (43%), Gaps = 12/192 (6%)
Query: 423 APRQVSANSEGMDNILVTWQPPRKDPSAVQEYVVEWRELHPGGDTQVPLNWLRSRPYNVS 482
AP + +++LV W P+ + S + Y +E RE++ ++V + L + NV
Sbjct: 14905 APDKPIVEDVTSNSMLVKWNEPKDNGSPILGYWLEKREVNSTHWSRVNKSLLNALKANVD 14964
Query: 483 ALISENIKSYICYEIRVYALSGDQGGCSSILGNSK-HKAPLS--GPHINAITEEKG-SIL 538
L+ + Y RV A + G S + K P+S GP I +T+ +I
Sbjct: 14965 GLLEG-----LTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIPRVTDTSSTTIE 15019
Query: 539 ISWNSIPVQEQMGCLLHYRIYWKERDSNSQPQLCEIPYRVSQNSHPINSLQPRVTYVLWM 598
+ W P G ++ Y + + +N + E +V Q + + ++ Y L +
Sbjct: 15020 LEWEP-PAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQ--YTVKEIREGADYKLRV 15076
Query: 599 TALTAAGESSHG 610
+A+ AAGE G
Sbjct: 15077 SAVNAAGEGPPG 15088
Score = 35.4 bits (80), Expect = 0.23
Identities = 47/201 (23%), Positives = 79/201 (39%), Gaps = 25/201 (12%)
Query: 423 APRQVSANSEGMDNILVTWQPPRKD-PSAVQEYVVEWRELHPGGDTQVPLNWLRSRPYNV 481
AP+ + D+++V W+ P D S + YV+E R+ T+ + V
Sbjct: 22739 APKAPEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRV 22798
Query: 482 SALISENIKSYICYEIRVYA-----------LSGDQGGCSSILGNSKHKAPLSGPHINAI 530
+ LI + YE RV A S Q C I P + P + I
Sbjct: 22799 TGLIENH-----DYEFRVSAENAAGLSEPSPPSAYQKACDPIY----KPGPPNNPKVIDI 22849
Query: 531 TEEKGSILISWNSIPVQEQMGCLLHYRIYWKERDSNSQPQLCEIPYRVSQNSHPINSLQP 590
T + S+ +SW S P+ + GC + I K S + +C P +++ + + L
Sbjct: 22850 T--RSSVFLSW-SKPIYDG-GCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLE 22905
Query: 591 RVTYVLWMTALTAAGESSHGN 611
+ Y + A+ AG H +
Sbjct: 22906 KHEYNFRICAINKAGVGEHAD 22926
Score = 35.4 bits (80), Expect = 0.23
Identities = 37/137 (27%), Positives = 61/137 (44%), Gaps = 12/137 (8%)
Query: 397 VSAANSKGSSLPTRINIMNLCEAGLL---APRQVSANSEGMDNILVTWQPPRKDPSA-VQ 452
VSA N+ G S P ++ + + ++ AP + + + D+ +V W+PP D A ++
Sbjct: 30798 VSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIR 30857
Query: 453 EYVVEWRELHPGGDTQVPLNWLRSRPYNVSALISENIKSYICYEIRVYALS-GDQGGCSS 511
Y +E RE V +R ++V LI E ++ YE RV + G + S
Sbjct: 30858 NYYLEKREKKQNKWISVTTEEIRETVFSVKNLI-EGLE----YEFRVKCENLGGESEWSE 30912
Query: 512 ILG--NSKHKAPLSGPH 526
I K P+ PH
Sbjct: 30913 ISEPITPKSDVPIQAPH 30929
Score = 35.0 bits (79), Expect = 0.30
Identities = 39/165 (23%), Positives = 66/165 (40%), Gaps = 13/165 (7%)
Query: 664 REIPDPANSTCAKKYPIAEEKTQLPLDRLLIDWP--TPEDPEPLVISEVLHQVTPVFRHP 721
+E P PA K P+ EEK +P+ + + P PE P+ V + + P
Sbjct: 9996 KEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEA 10055
Query: 722 PCSNWPQREKGIQGHQASEKDMMHSASSPPPPRALQAESRQLVDLYKVLESRGSDPKPEN 781
P + P+ K + + + +PPP + R+ V + L P+ E
Sbjct: 10056 PPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPK---VPKKREPVPVPVAL------PQEEE 10106
Query: 782 PACPWTVLPAGD-LPTHDGYLPSNIDDLPSHEAPLADSLEELEPQ 825
++P + LP + LP + LP E L + EE+ P+
Sbjct: 10107 VLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEE-EEIPPE 10150
Score = 34.7 bits (78), Expect = 0.39
Identities = 30/101 (29%), Positives = 49/101 (48%), Gaps = 9/101 (8%)
Query: 263 NSRLWNMVNVTKAKGR-HDLLDLKPFTEYEFQISSKLHLYKGSWSDWSESLRAQTPEEEP 321
NS LW VN + GR + L +Y+F++ ++ S SD S+ A +P +P
Sbjct: 27799 NSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSP-VDP 27857
Query: 322 TGMLDVWYMKRHIDYSRQQISLFWKNLSVSEARGKILHYQV 362
G D +ID +R+ I+L W N + + KI+ Y +
Sbjct: 27858 PGTPD------YIDVTRETITLKW-NPPLRDGGSKIVGYSI 27891
Score = 34.7 bits (78), Expect = 0.39
Identities = 43/213 (20%), Positives = 81/213 (38%), Gaps = 9/213 (4%)
Query: 140 TVACTWERGRDT--HLYTEYTLQLSGPKNLTWQKQCKDIYCDYLDFGINLTPESPESNFT 197
++ TW R +Y L+ K+ W K F + E E F
Sbjct: 28167 SITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFH 28226
Query: 198 AKVTAVNSLGSSSSLPSTFTFLDIVRPLPPWDIRIKFQKASVSRCTLYWR----DEGLVL 253
+G +S + + V P P + +K S + +L W D G+ +
Sbjct: 28227 VMAENAAGVGPASGISRLIKCREPVNPPGPPTV-VKVTDTSKTTVSLEWSKPVFDGGMEI 28285
Query: 254 LNRL-RYRPSNSRLWNMVNVTKA-KGRHDLLDLKPFTEYEFQISSKLHLYKGSWSDWSES 311
+ + ++ W+ VN K R+ + DL+ EY+F++S+ KG + + +
Sbjct: 28286 IGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGT 28345
Query: 312 LRAQTPEEEPTGMLDVWYMKRHIDYSRQQISLF 344
++A P +D + + H+ + I LF
Sbjct: 28346 IKAVDRLTAPELDIDANFKQTHVVRAGASIRLF 28378
Score = 33.5 bits (75), Expect = 0.87
Identities = 30/119 (25%), Positives = 56/119 (47%), Gaps = 7/119 (5%)
Query: 427 VSANSEGMDNILVTWQPPRKD-PSAVQEYVVEWRELHPGGDTQVPLNWLRSR-PYNVSAL 484
VS + D ++++W+PP D S + Y++E +E+ G D +P+ ++ VS L
Sbjct: 16919 VSFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEV--GKDVWMPVTSASAKTTCKVSKL 16976
Query: 485 ISENIKSYICYEIRVYALSGDQGGCSSILGNSKHKAPLSGPHINAITE-EKGSILISWN 542
+ + + +Y +S D S+ + + P P +TE K S L++WN
Sbjct: 16977 LEGKDYIFRIHAENLYGIS-DPLVSDSMKAKDRFRVP-DAPDQPIVTEVTKDSALVTWN 17033
Score = 33.1 bits (74), Expect = 1.1
Identities = 52/221 (23%), Positives = 94/221 (42%), Gaps = 22/221 (9%)
Query: 200 VTAVNSLGSSSSLPSTFTFLDIVRPLPPWDIRIKFQKASVSRCTLYWR----DEGLVLLN 255
+T N LGS+++ + I P P DI K + S C L W D G +L+
Sbjct: 14459 ITLENKLGSATA---SINVKVIGLPGPCKDI--KASDITKSSCKLTWEPPEFDGGTPILH 14513
Query: 256 R-LRYRPSNSRLWNMVNVTKAKGRHDLLDLKPFTEYEFQISSKLHLYKGSWSDWSESLRA 314
L R + R + V + K + DL P EY F++ + + G + + + A
Sbjct: 14514 YVLERREAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIA 14573
Query: 315 QTPEEEPTGMLDVWYMKRHIDYSRQQISLFWKNLSVSEARGKILHYQVTLQELTGGKAMT 374
Q P++ P +DV + H + + + +++ WK + + KI+ Y ++++ G+
Sbjct: 14574 QDPKQPPDPPVDV---EVH-NPTAEAMTITWKP-PLYDGGSKIMGY--IIEKIAKGEERW 14626
Query: 375 QNITGH-----TSWTTVIPRTGNWAVAVSAANSKGSSLPTR 410
+ H T + + V A N+ G S P+R
Sbjct: 14627 KRCNEHLVPILTYTAKGLEEGKEYQFRVRAENAAGISEPSR 14667
Score = 30.8 bits (68), Expect = 5.6
Identities = 29/113 (25%), Positives = 44/113 (38%), Gaps = 25/113 (22%)
Query: 676 KKYPIAEEKTQLPLDRLLIDWPTPEDPEPLVISE----VLHQVTPVFRHP--PCSNWPQR 729
K P+AEE+ PE P P V E + + PV + P P P+
Sbjct: 10822 KPVPVAEEEE-------------PEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEP 10868
Query: 730 EKGIQGHQASEKDMMHSASSPPPPRALQAESRQLVDLYKVLESRGSDPKPENP 782
EK I EK + PPPP + + ++ + K + + KP+ P
Sbjct: 10869 EKVI------EKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVP 10915
Score = 30.8 bits (68), Expect = 5.6
Identities = 71/354 (20%), Positives = 136/354 (38%), Gaps = 31/354 (8%)
Query: 124 PEQPQNLSCIQKGEQGTVACTWERGR--DTHLYTEYTLQLSGPKNLTWQKQCKDIYCDYL 181
P P N++ G V+ TWE T Y ++L ++ W + + L
Sbjct: 13191 PGPPLNVTITDVNRFG-VSLTWEPPEYDGGAEITNYVIELRDKTSIRWDT-AMTVRAEDL 13248
Query: 182 DFGINLTPESPESNFTAKVTAVNSLG---SSSSLPSTFTFLDIVRPLPPWDIRIKFQKAS 238
+ E E +F +V A N +G S++ P I RP PP + + +
Sbjct: 13249 SATVTDVVEGQEYSF--RVRAQNRIGVGKPSAATPFVKVADPIERPSPP--VNLTSSDQT 13304
Query: 239 VSRCTLYW----RDEGLVLLNRLRYRPSNSR-LWNMVNVTKAKG-RHDLLDLKPFTEYEF 292
S L W +D G +L + R + W N+ + + L+ +Y +
Sbjct: 13305 QSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLY 13364
Query: 293 QISSKLHLYKGSWSDWSESLRAQTPEE---EPTGMLDVWYMKRHIDYS-RQQISLFWKNL 348
++S++ K SD SE L T ++ EPT +D+ K ++ I++ +
Sbjct: 13365 RVSAE---NKAGVSDPSEILGPLTADDAFVEPT--MDLSAFKDGLEVIVPNPITILVPST 13419
Query: 349 SVSEARGKILHYQVTLQELTGGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLP 408
L+ TG + + ++ + + + ++ ++
Sbjct: 13420 GYPRPTATWCFGDKVLE--TGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTIS 13477
Query: 409 TRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKD-PSAVQEYVVEWREL 461
I++ + AP+++ D++ +TW+PP D S + YVVE RE+
Sbjct: 13478 GEIDVNVIARPS--APKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREV 13529
Score = 30.4 bits (67), Expect = 7.4
Identities = 45/205 (21%), Positives = 78/205 (38%), Gaps = 27/205 (13%)
Query: 155 TEYTLQLSGPKNLTWQK---QCKDIYCDYLDFGINLTPESPESNFTAKVTAVNSLGSSSS 211
T Y ++ + WQ KD C +TP + S + +V A N++G S
Sbjct: 14116 TNYIVEKRDVRRKGWQTVDTTVKDTKC-------TVTPLTEGSLYVFRVAAENAIGQSDY 14168
Query: 212 LPSTFTFL---DIVRPLPPWDIRIKFQKASVSRCTLYW---RDEGLVLLNRLRYRPSNSR 265
+ L P PP+ + + + L W +++G + R
Sbjct: 14169 TEIEDSVLAKDTFTTPGPPYALAVV--DVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERL 14226
Query: 266 LWNMVNVTKAKG---RHDLLDLKPFTEYEFQISSKLHLYKGSWSDWSESLRAQTPEEEPT 322
V K G + D+ TE +FQ+ ++ G S+ +E L + P P+
Sbjct: 14227 GTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPS 14286
Query: 323 GMLDVWYMKRHI-DYSRQQISLFWK 346
LD+ H+ D R+ I++ WK
Sbjct: 14287 PPLDL-----HVTDAGRKHIAIAWK 14306
Score = 30.4 bits (67), Expect = 7.4
Identities = 24/81 (29%), Positives = 36/81 (44%), Gaps = 6/81 (7%)
Query: 424 PRQVSANSEGMDNILVTWQPPRKD-PSAVQEYVVEWRELHPGGDTQVPLNWLRSRPYNVS 482
P + + + +TW PP+ D S + YV+E R + +V + L SR Y V
Sbjct: 16720 PEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVK 16779
Query: 483 ALISENIKSYICYEIRVYALS 503
L K YE RV A++
Sbjct: 16780 GL-----KEGDTYEYRVSAVN 16795
Score = 30.4 bits (67), Expect = 7.4
Identities = 58/287 (20%), Positives = 110/287 (38%), Gaps = 33/287 (11%)
Query: 232 IKFQKASVSRCTLYWRDE----GLVLLNRL-RYRPSNSRLWNMVNVTKAKGRHDLLDLKP 286
I+ S C L W + G + N + R S + W +VN + + + + L
Sbjct: 28748 IEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTK 28807
Query: 287 FTEYEFQISSKLHLYKGSWSDWSESLRAQTPEEEPTGML--DVWYMKRHIDYSRQQISLF 344
+ EY F++SS+ + + S S + A+ P P+ +V+++ S +S+
Sbjct: 28808 YMEYSFRVSSE-NRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHV------SANAMSIR 28860
Query: 345 WKNLSVSEARGKILHYQVTLQELTGGKAMTQNITGHTSW---TTVIPRTGNWAVAVSAAN 401
W+ + KI+ Y V +E + +N T + + A N
Sbjct: 28861 WEE-PYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALN 28919
Query: 402 SKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKD-PSAVQEYVVEWRE 460
+ G S + + + + + AP + + + W P D S V Y++E +
Sbjct: 28920 AAGVSKASEASRPIMAQNPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKP 28979
Query: 461 LHPGGDTQVPLNWLRSRPYNVSALISENIKSYIC------YEIRVYA 501
+ GD + WL+ ++S+N + YE RV A
Sbjct: 28980 VSEVGDGR----WLKCN----YTIVSDNFFTVTALSEGDTYEFRVLA 29018
Score = 30.0 bits (66), Expect = 9.6
Identities = 26/117 (22%), Positives = 49/117 (41%), Gaps = 8/117 (6%)
Query: 682 EEKTQLPLDRLLIDWPTPEDPEPLVISEVLHQVTPVFRHPPCSNWPQREKGIQGHQASEK 741
EE+ + + + ++ E+PE V+ E LH ++ P ++EK I K
Sbjct: 9511 EEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPAEVTERQEKKI-----VLK 9565
Query: 742 DMMHSASSPPPPRALQAESRQLVDLYKV---LESRGSDPKPENPACPWTVLPAGDLP 795
+ + PPP + +++V KV + + P P+ P P +P +P
Sbjct: 9566 PKIPAKIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKVPEEPKKPVPEKKVP 9622
Score = 30.0 bits (66), Expect = 9.6
Identities = 55/255 (21%), Positives = 92/255 (36%), Gaps = 28/255 (10%)
Query: 124 PEQPQNLSCIQKGEQGTVACTWERGRDTH--LYTEYTLQLSGPKNLTWQKQCKDIYCDYL 181
P +NL + C W+ D Y L+ K + W + L
Sbjct: 18297 PGPVRNLKIVDVSSDRCTVC-WDPPEDDGGCEIQNYILEKCETKRMVWSTYSATV----L 18351
Query: 182 DFGINLTPESPESNFTAKVTAVNSLGSSSSLPSTFTFLDIV-----RPLPPWDIRIKFQK 236
G +T + + +V A N +G+ S RP PP + K
Sbjct: 18352 TPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAKTKYDKPGRPDPP-----EVTK 18406
Query: 237 ASVSRCTLYWR----DEGLVLLNR-LRYRPSNSRLWNMVNVTKAKGRH-DLLDLKPFTEY 290
S T+ W D G + L + +S W VN + R + +L P EY
Sbjct: 18407 VSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEY 18466
Query: 291 EFQISSKLHLYKGSWSDWSESLRAQTPEEEPTGMLDVWYMKRHIDYSRQQISLFWKNLSV 350
+F++ ++ + G S S + A+ P E P + R +D ++ I+L W V
Sbjct: 18467 QFRVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNF----RVVDTTKHSITLGW-GKPV 18521
Query: 351 SEARGKILHYQVTLQ 365
+ I+ Y V ++
Sbjct: 18522 YDGGAPIIGYVVEMR 18536
Score = 30.0 bits (66), Expect = 9.6
Identities = 38/175 (21%), Positives = 68/175 (38%), Gaps = 21/175 (12%)
Query: 456 VEWRELHPGGDTQVPLNWLRSRPYNVSALISEN-------------IKSYICYEIRVYAL 502
+ W E + G +++ W+ + N + EN + + Y+ R YAL
Sbjct: 28859 IRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYAL 28918
Query: 503 SGDQGGCSSILGNSKH---KAPLSGPHINAITE-EKGSILISWNSIPVQEQMGCLLHYRI 558
+ G S S+ + P+ P +T+ + ++ + W S P + ++ Y I
Sbjct: 28919 NA--AGVSKASEASRPIMAQNPVDAPGRPEVTDVTRSTVSLIW-SAPAYDGGSKVVGYII 28975
Query: 559 YWKERDSNSQPQLCEIPYR-VSQNSHPINSLQPRVTYVLWMTALTAAGESSHGNE 612
K + + Y VS N + +L TY + A AAG S G+E
Sbjct: 28976 ERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSE 29030
>gi|110349717 titin isoform novex-2 [Homo sapiens]
Length = 27118
Score = 56.2 bits (134), Expect = 1e-07
Identities = 73/311 (23%), Positives = 133/311 (42%), Gaps = 24/311 (7%)
Query: 200 VTAVNSLGSSSSLPSTFTFLDIVRPLPPWDIRIKFQKASVSRCTLYWRDE----GLVLLN 255
VTA NS G+++ + + + +P PP ++F + S + W G + N
Sbjct: 18079 VTATNSAGTATE---NLSVIVLEKPGPPVG-PVRFDEVSADFVVISWEPPAYTGGCQISN 18134
Query: 256 RL-RYRPSNSRLWNMVNVTKAKGRHDLLDLKPFTEYEFQISSKLHLYKGSWSDWSESLRA 314
+ R + + W+MV+ T A+ + LK TEY+F+I ++ K + D S+++
Sbjct: 18135 YIVEKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAPLD-SKAVIV 18193
Query: 315 QTPEEEPTGMLDVWYMKRHIDYSRQQISLFWKNLSVSEARGKILHYQVTLQE---LTGGK 371
Q P +EP G ++ S+ Q+ + W V++ KI+ Y + +E + K
Sbjct: 18194 QYPFKEP-GPPGTPFV---TSISKDQMLVQWHE-PVNDGGTKIIGYHLEQKEKNSILWVK 18248
Query: 372 AMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANS 431
I TT + + VSA N G P++++ + P + A
Sbjct: 18249 LNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAIV 18308
Query: 432 EGMDNILVTWQPPRKD-PSAVQEYVVEWRELHPGGDTQVPLNWLRSRPYNVSALISENIK 490
+N+ + W+ P D S + Y+VE ++L G + + + VS L+ +
Sbjct: 18309 ITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQ-- 18366
Query: 491 SYICYEIRVYA 501
YE RV A
Sbjct: 18367 ---RYEFRVIA 18374
Score = 52.0 bits (123), Expect = 2e-06
Identities = 77/334 (23%), Positives = 133/334 (39%), Gaps = 27/334 (8%)
Query: 183 FGINLTPESPESNFTAKVTAVNS---LGSSSSLPSTFTFLDIV---RPLPPWDIRIKFQK 236
F +T E+ N VTA + +++S +T F++IV RP PP +
Sbjct: 20218 FNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTG-PVVISD 20276
Query: 237 ASVSRCTLYWR----DEGLVLLNR-LRYRPSNSRLWNMVNVTKAKGRHDLLDLKPFTEYE 291
+ TL W D G + N L R +++ +W V+ T A+ ++ L EY+
Sbjct: 20277 ITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQ 20336
Query: 292 FQISSKLHLYKGSWSDWSESLRAQTPEEEPTGMLDVWYMKRHIDYSRQQISLFWKNLSVS 351
F+I ++ D S + + P P W + +R+ I++ W VS
Sbjct: 20337 FRIKAENRFGISDHID-SACVTVKLPYTTPGPPSTPWV----TNVTRESITVGWHE-PVS 20390
Query: 352 EARGKILHYQVTLQE---LTGGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLP 408
++ Y + +++ + KA I T I + V A N+ G P
Sbjct: 20391 NGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGVGKP 20450
Query: 409 TRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKD-PSAVQEYVVEWRELHPGGDT 467
+ + L PR V +++ ++WQ P D S + Y+VE R+L G T
Sbjct: 20451 SHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWT 20510
Query: 468 QVPLNWLRSRPYNVSALISENIKSYICYEIRVYA 501
+ + + +S L + YE RV+A
Sbjct: 20511 KASFTNVTETQFIISGLTQNS-----QYEFRVFA 20539
Score = 48.5 bits (114), Expect = 3e-05
Identities = 69/312 (22%), Positives = 130/312 (41%), Gaps = 29/312 (9%)
Query: 203 VNSLGSSSSLPSTFTFLDIVRPLPPWDIRIKFQKASVSRCTLYWR----DEGLVLLNRL- 257
V S+ T + + +P PP +K + + TL W D G + N +
Sbjct: 15915 VKLTNSAGEAIETLNVIVLDKPGPPTG-PVKMDEVTADSITLSWGPPKYDGGSSINNYIV 15973
Query: 258 RYRPSNSRLWNMVNVTKAKGRHDLLDLKPFTEYEFQISSKLHLYKGSWSDWSESLRAQTP 317
R +++ W +V+ T A+ LK EY+F+I+++ K ++ + SE AQ P
Sbjct: 15974 EKRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGKSTYLN-SEPTVAQYP 16032
Query: 318 EEEP----TGMLDVWYMKRHIDYSRQQISLFWKNLSVSEARGKILHYQVTLQELTGGKAM 373
+ P T ++ + SR + + W N +S+ +++ Y + +E +
Sbjct: 16033 FKVPGPPGTPVVTL--------SSRDSMEVQW-NEPISDGGSRVIGYHLERKERNSILWV 16083
Query: 374 TQNIT--GHTSW-TTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSAN 430
N T T + TT + + VSA N G P++++ + P + A
Sbjct: 16084 KLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAI 16143
Query: 431 SEGMDNILVTWQPPRKD-PSAVQEYVVEWRELHPGGDTQVPLNWLRSRPYNVSALISENI 489
+++ + W+ P D S + Y+VE +EL G + + + V+ L+ ++
Sbjct: 16144 IVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDH- 16202
Query: 490 KSYICYEIRVYA 501
YE RV A
Sbjct: 16203 ----RYEFRVIA 16210
Score = 46.2 bits (108), Expect = 1e-04
Identities = 76/334 (22%), Positives = 137/334 (41%), Gaps = 41/334 (12%)
Query: 185 INLTPESPESNFTAKVTAVNSLGSSSSLPSTFTFLDIVRPLPPWDIRIKFQKASVSRCTL 244
+++ S E T ++ NS GS + +P T LD RP PP IRI + S T+
Sbjct: 19147 LSIKEASKEDVGTYELCVSNSAGSIT-VPITIIVLD--RPGPPGPIRI--DEVSCDSITI 19201
Query: 245 YWR----DEGLVLLNRL-RYRPSNSRLWNMVNVTKAKGRHDLLDLKPFTEYEFQISSKLH 299
W D G + N + + + S W++V+ A+ ++ L +EY+F++ ++
Sbjct: 19202 SWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENR 19261
Query: 300 LYKGSWSDWSESLRAQTP--EEEPTGMLDVWYMKRHIDYSRQQISLFWKNLSVSEARGKI 357
K S+S+ S ++ A+ P P G V + ++ + + W+ + V++ ++
Sbjct: 19262 YGKSSYSE-SSAVVAEYPFSPPGPPGTPKV------VHATKSTMLVTWQ-VPVNDGGSRV 19313
Query: 358 LHYQVTLQE---LTGGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKG----SSLPTR 410
+ Y + +E + KA I + + + V A N G S
Sbjct: 19314 IGYHLEYKERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEP 19373
Query: 411 INIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKDPSA-VQEYVVEWRELHPGGDTQV 469
+ + C+ P Q + ++ + W P D A + Y+VE REL G
Sbjct: 19374 VPARDPCD----PPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDG----- 19424
Query: 470 PLNWLRSRPYNVSALISE--NIKSYICYEIRVYA 501
WL+ N+ E + YE RV+A
Sbjct: 19425 --RWLKCNYTNIQETYFEVTELTEDQRYEFRVFA 19456
Score = 42.4 bits (98), Expect = 0.002
Identities = 34/127 (26%), Positives = 64/127 (50%), Gaps = 10/127 (7%)
Query: 200 VTAVNSLGSSSSLPSTFTFLDIVRPLPPWDIRIKFQKASVSRCTLYWRDE----GLVLLN 255
+T N +G ++ + + + +P PP +KF S TL W G + N
Sbjct: 16997 ITVANVVGQKTA---SIEIVTLDKPDPPKG-PVKFDDVSAESITLSWNPPLYTGGCQITN 17052
Query: 256 RL-RYRPSNSRLWNMVNVTKAKGRHDLLDLKPFTEYEFQISSKLHLYKGSWSDWSESLRA 314
+ + R + + +W++V+ T A+ + LK TEY+F+I ++ + Y S++ S+ + A
Sbjct: 17053 YIVQKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFAE-NRYGQSFALESDPIVA 17111
Query: 315 QTPEEEP 321
Q P +EP
Sbjct: 17112 QYPYKEP 17118
Score = 40.8 bits (94), Expect = 0.005
Identities = 56/231 (24%), Positives = 103/231 (44%), Gaps = 19/231 (8%)
Query: 200 VTAVNSLGSSSSLPSTFTFLDIVRPLPPWDIRIKFQKASVSRCTLYWR----DEGLVLLN 255
+T NS GS S+ + LD P PP D+++K + + + TL W D G + N
Sbjct: 15626 LTVENSSGSKSAFVNV-RVLDT--PGPPQDLKVK--EVTKTSVTLTWDPPLLDGGSKIKN 15680
Query: 256 RL-RYRPSNSRLWNMVNVTKAKGRHDLLDLKPFTEYEFQISSKLHLYKGSWSDWSESLRA 314
+ R S + ++ V K + L+ Y F++ ++ G ++ +ES++A
Sbjct: 15681 YIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKA 15740
Query: 315 QTPEEEPTGMLDVWYMKRHIDYSRQQISLFWKNLSVSEARGKILHYQVTLQELTGGKAMT 374
+ P G + + +D +R +SL W+ + +IL Y V +Q K T
Sbjct: 15741 -SERPLPPGKITL------MDVTRNSVSLSWEKPE-HDGGSRILGYIVEMQTKGSDKWAT 15792
Query: 375 QNITGHTSWT-TVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAP 424
T T T + + ++ VSA N KG S P ++++ + + ++ P
Sbjct: 15793 CATVKVTEATITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKDLVIPP 15843
Score = 39.7 bits (91), Expect = 0.012
Identities = 81/353 (22%), Positives = 136/353 (38%), Gaps = 33/353 (9%)
Query: 127 PQNLSCIQKGEQGTVACTWER-----GRDTHLYTEYTLQLSGPKNLTWQKQCKDIYCDYL 181
P + + K + ++ W R G D + Y L+ K+L W K K+ D
Sbjct: 20763 PPGIPEVTKITKNSMTVVWSRPIADGGSDI---SGYFLEKRDKKSLGWFKVLKETIRDTR 20819
Query: 182 DFGINLTPESPESNFTAKVTAVNSLGSSS-SLPSTFTFL--DIVRPLPPWDIRIKFQKAS 238
LT S ++ +V AVN+ G S PS F I P PP IRI ++
Sbjct: 20820 QKVTGLTENS---DYQYRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIA--DST 20874
Query: 239 VSRCTLYWR----DEGLVLLNRL-RYRPSNSRLWNMVNVTKAKGR---HDLLDLKPFTEY 290
S TL W D G + + R W V+ TK + R + + +LKP Y
Sbjct: 20875 KSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVS-TKGEVRTTEYVVSNLKPGVNY 20933
Query: 291 EFQISSKLHLYKGSWSDWSESLRAQTPEEEPTGMLDVWYMKRHIDYSRQQISLFWKNLSV 350
F++S+ +G + +E ++A+ E P LDV I + + + + +
Sbjct: 20934 YFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQVL---IPF 20990
Query: 351 SEARGKILHYQVTLQELTGGKAMTQNITGHTSWTTV--IPRTGNWAVAVSAANSKGSSLP 408
+ ++ + L + T +S T+ + R ++ N G
Sbjct: 20991 KGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKS 21050
Query: 409 TRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKD-PSAVQEYVVEWRE 460
+ +++ L QV S G + + W PP D S + YV+E R+
Sbjct: 21051 STVSVKVLDTPAACQKLQVKHVSRG--TVTLLWDPPLIDGGSPIINYVIEKRD 21101
Score = 38.1 bits (87), Expect = 0.035
Identities = 74/344 (21%), Positives = 116/344 (33%), Gaps = 53/344 (15%)
Query: 182 DFGINLTPESPESNFTAKVTAVNSLGSSSSLPSTFTFLDIVRPLPPWDIRIKFQKASVSR 241
+F + E+ E F +G + L +I+ P P D+ +K + R
Sbjct: 12256 EFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEP-PEIDLDASMRKLVIVR 12314
Query: 242 CTLYWRDEGLVLLNRLRYRPSNSRLWNMVNVTKA--KGRHDLLDLKPFTEYEFQISSKLH 299
R L +R RP+ W V + KG+ DL+D F
Sbjct: 12315 AGCPIR-----LFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMAFL----------- 12358
Query: 300 LYKGSWSDWSESLRAQTPEEEPTGMLDVWYMKRHIDYSRQQISLFWKNLSVSEARGKILH 359
+ S D +S + P G V+ R +D +L VS+ H
Sbjct: 12359 VIPNSTRD--DSGKYSLTLVNPAGEKAVFVNVRVLDTPGPV-----SDLKVSDVTKTSCH 12411
Query: 360 YQVTLQELTGGKAMTQNIT-----GHTSWTTVIPRT------------GN-WAVAVSAAN 401
E GG +T I +W+TV P GN + V+A N
Sbjct: 12412 VSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVN 12471
Query: 402 SKGSSLPTRINIMNLCEAGLLAP---RQVSANSEGMDNILVTWQPPRKDPSA-VQEYVVE 457
G +PT + L L P R++ ++ + W PP +D A + Y+
Sbjct: 12472 EYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITS 12531
Query: 458 WRELHPGGDTQVPLNWLRSRPYNVSALISENIKSYICYEIRVYA 501
+RE D W +L+ +K Y+ RV A
Sbjct: 12532 YREEEQPAD-----RWTEYSVVKDLSLVVTGLKEGKKYKFRVAA 12570
Score = 37.7 bits (86), Expect = 0.046
Identities = 43/183 (23%), Positives = 74/183 (40%), Gaps = 18/183 (9%)
Query: 124 PEQPQNLSCIQKGEQGTVACTWERGRDT--HLYTEYTLQLSGPKNLTWQKQCKDIYCDYL 181
PE P N + + +V+ +W R +D T Y ++ W + K +
Sbjct: 24024 PEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTM 24083
Query: 182 DFGINLTPESPESNFTAKVTAVNSLGSSSSLPSTFTFL---DIVRPLPPWDIRI-KFQKA 237
+T P++ + ++ A N +G S + P++ + +P P ++ I K
Sbjct: 24084 ---YTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKD 24140
Query: 238 SVSRCTLYWR----DEGLVLLNR-LRYRPSNSRLWNMVNVTKAKGRHDLL-DLKPFTEYE 291
SV TL W D G +L + YR S W N + K + + L TEYE
Sbjct: 24141 SV---TLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYE 24197
Query: 292 FQI 294
F++
Sbjct: 24198 FRV 24200
Score = 37.4 bits (85), Expect = 0.060
Identities = 90/379 (23%), Positives = 149/379 (39%), Gaps = 44/379 (11%)
Query: 196 FTAKVTAVNSLGSSSSLPSTFTFL---DIVRPLPP-WDIRIKFQKASVS-RCTLYWRDEG 250
++ +V AVN G S + L + P PP W I K + + T+ +D G
Sbjct: 7748 YSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGG 7807
Query: 251 LVLLNRL-RYRPSNSRLWNMVNVTKAKGRHDLLDLKPFTEYEFQISSKLHLYKGSWSDWS 309
+ N + R + W V+ T + + L + Y F+++++ + + +++
Sbjct: 7808 SPITNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIE 7867
Query: 310 ESLRAQ---TPEEEPTGMLDVWYMKRHIDYSRQQISLFWKNLSVSEARGKILHYQVTLQE 366
+S+ A+ T P + V KRH+D L W+ R I Y + +E
Sbjct: 7868 DSVLAKDTFTTPGPPYALAVVDVTKRHVD-------LKWEPPKNDGGR-PIQRYVIEKKE 7919
Query: 367 LTGGKAMTQNITGHTSW----TTVIPRTGNWAVAVSAANSKG---SSLPTRINIMNLCEA 419
G + + T T VI T V A N G S PT I + +
Sbjct: 7920 RLGTRWVKAGKTAGPDCNFRVTDVIEGT-EVQFQVRAENEAGVGHPSEPTEILSIEDPTS 7978
Query: 420 GLLAPRQVSANSEGMDNILVTWQPPRKD-PSAVQEYVVEWRELHPGGDTQVPLNWLR--S 476
P + G +I + W+PP K+ S + Y V E+ P G + W+R S
Sbjct: 7979 PPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHV---EMCPVGTEK----WMRVNS 8031
Query: 477 RPY-NVSALISENIKSYICYEIRVYALSG-DQGGCSSILGNSKHKAPLSGPHIN------ 528
RP ++ + E + Y +RV A++ S I N K P P I+
Sbjct: 8032 RPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHDI 8091
Query: 529 -AITEEKGSILISWNSIPV 546
I EK SI + + ++PV
Sbjct: 8092 IVIEGEKLSIPVPFRAVPV 8110
Score = 36.6 bits (83), Expect = 0.10
Identities = 59/287 (20%), Positives = 108/287 (37%), Gaps = 25/287 (8%)
Query: 335 DYSRQQISLFWKNLSVSEARGKILHYQVTLQELTGGKAMTQNITGHTSWTTV----IPRT 390
+ ++ + + WK + + KI +Y + +E+ GK + +T ++ TT +
Sbjct: 10618 EVTKDYMVISWKP-PLDDGGSKITNYIIEKKEV--GKDVWMPVTSASAKTTCKVSKLLEG 10674
Query: 391 GNWAVAVSAANSKGSSLPTRINIMNLCEAGLL--APRQVSANSEGMDNILVTWQPPRKDP 448
++ + A N G S P + M + + AP Q D+ LVTW P
Sbjct: 10675 KDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGG 10734
Query: 449 SAVQEYVVEWRELHPGGDTQVPLNWLRSRPYNVSALISENIKSYI--C-YEIRVYALS-- 503
+ Y++E RE + W R + + + C YE RV A +
Sbjct: 10735 KPITNYILEKRE-------TMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEI 10787
Query: 504 --GDQGGCSS-ILGNSKHKAPLSGPHINAITEEKGSILISWNSIPVQEQMGCLLHYRIYW 560
GD S + P + AI S+ ++W P + +L Y + +
Sbjct: 10788 GIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQP-PRHDGGSKILGYIVEY 10846
Query: 561 KERDSNSQPQLCEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAGES 607
++ + P + + + L+ TY + A+ AAGES
Sbjct: 10847 QKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGES 10893
Score = 36.6 bits (83), Expect = 0.10
Identities = 52/217 (23%), Positives = 91/217 (41%), Gaps = 23/217 (10%)
Query: 397 VSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKD-PSAVQEYV 455
++A NS GS T I + L + G P V N D +++W+PP +D S + Y+
Sbjct: 13063 ITAENSSGSKSAT-IKLKVLDKPG--PPASVKINKMYSDRAMLSWEPPLEDGGSEITNYI 13119
Query: 456 VEWRELHPGGDTQVPLNWLR-SRPYNVSALISENIKSYICYEIRVYALS----GDQGGCS 510
V+ RE T P NW + S +++ E + Y+ R+ A + GD
Sbjct: 13120 VDKRE------TSRP-NWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTE 13172
Query: 511 SILGNSKHKAP--LSGPHINAITEEKGSILISWNSIPVQEQMGCLLHYRIYWKERDSNSQ 568
+ + + P P I+ IT K + +SW P + + Y + +E + +
Sbjct: 13173 PAIAKNPYDPPGRCDPPVISNIT--KDHMTVSWKP-PADDGGSPITGYLLEKRETQAVNW 13229
Query: 569 PQLCEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAG 605
++ P + + + LQ Y +TA+ AG
Sbjct: 13230 TKVNRKP--IIERTLKATGLQEGTEYEFRVTAINKAG 13264
Score = 36.6 bits (83), Expect = 0.10
Identities = 41/176 (23%), Positives = 71/176 (40%), Gaps = 9/176 (5%)
Query: 391 GNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKDPSA 450
G + + VS NS GS + I I+ L G P + + D+I ++W PP D
Sbjct: 19158 GTYELCVS--NSAGS-ITVPITIIVLDRPG--PPGPIRIDEVSCDSITISWNPPEYDGGC 19212
Query: 451 -VQEYVVEWRELHPGGDTQVPLNWLRSRPYNVSALISENIKSYICYEIRVYALSGDQGGC 509
+ Y+VE +E V R+ V + +C E R S +
Sbjct: 19213 QISNYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSES-- 19270
Query: 510 SSILGNSKHKAPLSGPHINAITEEKGSILISWNSIPVQEQMGCLLHYRIYWKERDS 565
S+++ P + K ++L++W +PV + ++ Y + +KER S
Sbjct: 19271 SAVVAEYPFSPPGPPGTPKVVHATKSTMLVTW-QVPVNDGGSRVIGYHLEYKERSS 19325
Score = 36.6 bits (83), Expect = 0.10
Identities = 68/306 (22%), Positives = 116/306 (37%), Gaps = 59/306 (19%)
Query: 164 PKNLTWQKQCKDIYCDY------LDFGINLTPESPESNFTAK--VTAVNSLGSSSSLPST 215
P +TW+K K++ D D LT N T K +T N +G S +
Sbjct: 20995 PPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVS 21054
Query: 216 FTFLDIVRPLPPWDIRIKFQKASVSRCTLYWR----DEGLVLLNR-LRYRPSNSRLWNMV 270
LD P +++ + S TL W D G ++N + R + R W++V
Sbjct: 21055 VKVLDT----PAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVV 21110
Query: 271 NVTKAKGRHDLLDLKPFTEYEFQISSKLHLYKGSWSDWSESLRAQTPEEEPTGMLDVWYM 330
+ + L+DL T + F++ ++ + G + +E ++A E P + D+ M
Sbjct: 21111 SHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKA---AEVPAPIRDL-SM 21166
Query: 331 KRHIDYSRQQISLFWKNLSVSEARGKILHYQVTLQELTGGKAMTQNITGHTSWTTVIPRT 390
K D ++ + L W T + GG +T+ V+ R
Sbjct: 21167 K---DSTKTSVILSW-----------------TKPDFDGGSVITE---------YVVERK 21197
Query: 391 GNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKDPSA 450
G S A G S I + L E +L R + N +G+ + P P
Sbjct: 21198 GKGEQTWSHA---GISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSD------PVTIGPIT 21248
Query: 451 VQEYVV 456
V+E ++
Sbjct: 21249 VKELII 21254
Score = 36.2 bits (82), Expect = 0.13
Identities = 76/327 (23%), Positives = 120/327 (36%), Gaps = 50/327 (15%)
Query: 164 PKNLTWQKQCKDIYCDYLDFGINLTPESPESNFTAK-----------VTAVNSLGSSSSL 212
PK+ +W K KDI + I TP S S T K +TA N G+
Sbjct: 14104 PKS-SWSKAGKDIRPSDIT-QITSTPTS--SMLTIKYATRKDAGEYTITATNPFGTKVEH 14159
Query: 213 PSTFTFLDIVRPLPPWDIRIKFQKASVSRCTLYW----RDEGLVLLNRLRYRPSNSRL-W 267
T LD+ P PP + I S + TL W D G + + + + SRL W
Sbjct: 14160 VKV-TVLDV--PGPPGPVEIS--NVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLW 14214
Query: 268 NMVNVTKAKGRHDLLDLKPFTEYEFQISSKLHLYKGSWSDWSESLRAQTPEEEPTGMLDV 327
+V+ RH L EY F++S+ H KG + + EP M+D
Sbjct: 14215 TVVSEDIQSCRHVATKLIQGNEYIFRVSAVNHYGKG-----------EPVQSEPVKMVDR 14263
Query: 328 W------YMKRHIDYSRQQISLFWKNLSVSEARGKILHYQVTLQE---LTGGKAMTQNIT 378
+ + ++ ++ WK V + +I Y V +E L +A+ ++
Sbjct: 14264 FGPPGPPEKPEVSNVTKNTATVSWKR-PVDDGGSEITGYHVERREKKSLRWVRAIKTPVS 14322
Query: 379 GHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVS---ANSEGMD 435
T + + VSA N G P+ + L + P S
Sbjct: 14323 DLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKK 14382
Query: 436 NILVTWQPPRKDPS-AVQEYVVEWREL 461
+ + W P D + YVVE +++
Sbjct: 14383 SASLAWGKPHYDGGLEITGYVVEHQKV 14409
Score = 35.8 bits (81), Expect = 0.18
Identities = 42/195 (21%), Positives = 85/195 (43%), Gaps = 21/195 (10%)
Query: 289 EYEFQISSKLHLYKGSWSDWSESLRAQTPEEEPTGMLDVWYMKRHIDYSRQQISLFWKNL 348
EY F++S++ + G + + A++ + P L+V D +R +SL W+
Sbjct: 6854 EYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTIT----DVNRFGVSLTWEPP 6909
Query: 349 SVSEARGKILHYQVTLQELTGGK---AMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGS 405
+ +I +Y + L++ T + AMT ++ T + ++ V A N G
Sbjct: 6910 EY-DGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGV 6968
Query: 406 SLPTR----INIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKD-PSAVQEYVVEWRE 460
P+ + + + E P ++++ + ++ + W+PP KD S + Y++E
Sbjct: 6969 GKPSAATPFVKVADPIERPS-PPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYIIE--R 7025
Query: 461 LHPGGDTQVPLNWLR 475
G D NW+R
Sbjct: 7026 CEEGKD-----NWIR 7035
Score = 35.8 bits (81), Expect = 0.18
Identities = 62/283 (21%), Positives = 112/283 (39%), Gaps = 28/283 (9%)
Query: 339 QQISLFWKNLSVSEARGKILHYQVTLQELTG--GKAMTQNITGHTSWTTVIPRTGNWAVA 396
++I+L W+ + KI HY V +E + +++++ TT I + +
Sbjct: 20676 EKITLLWRP-PADDGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFR 20734
Query: 397 VSAANSKGSSLPTRINIMNLCEA-------GLLAPRQVSANSEGMDNILVTWQPPRKDP- 448
V A N G P + + A G+ +++ NS + V W P D
Sbjct: 20735 VRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNS-----MTVVWSRPIADGG 20789
Query: 449 SAVQEYVVEWRELHPGGDTQVPLNWLRSRPYNVSALISENIKSYICYEIRVYALSG-DQG 507
S + Y +E R+ G +V +R V+ L +EN Y+ RV A++ QG
Sbjct: 20790 SDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGL-TENSD----YQYRVCAVNAAGQG 20844
Query: 508 GCSSILGNSKHKAPLSGP----HINAITEEKGSILISWNSIPVQEQMGCLLHYRIYWKER 563
S K P+ P I K SI + W+ PV + + Y + ++
Sbjct: 20845 PFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSK-PVYDGGSAVTGYVVEIRQG 20903
Query: 564 DSNSQPQLCEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAGE 606
+ + V + +++L+P V Y ++A+ AG+
Sbjct: 20904 EEEEWTTV-STKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQ 20945
Score = 35.8 bits (81), Expect = 0.18
Identities = 53/246 (21%), Positives = 98/246 (39%), Gaps = 18/246 (7%)
Query: 369 GGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAP---R 425
G +++++T T T + + V+A N G + ++ C + + P
Sbjct: 23573 GWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIGSYLQSEVIE-CRSSIRIPGPPE 23631
Query: 426 QVSANSEGMDNILVTWQPPRKD-PSAVQEYVVEWRELHPGGDTQVPLNWLRSRPYNVSAL 484
+ D + +TW PP D S V Y+VE +E+ D V +N + P ++
Sbjct: 23632 TLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVR--ADRWVRVNKV---PVTMTRY 23686
Query: 485 ISENIKSYICYEIRVYAL----SGDQGGCSSILGNSKHKAPLSGPHINAITE-EKGSILI 539
S + + YE RV A+ SG S + AP P +T+ + S+ +
Sbjct: 23687 RSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSL 23746
Query: 540 SWNSIPVQEQMGCLLHYRIYWKERDSNSQPQLCEIPYRVSQNSHPINSLQPRVTYVLWMT 599
+W S+P E + Y I ++ D + + P ++ + + + L Y +
Sbjct: 23747 AW-SVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIRE--YTLTHLPQGAEYRFRVL 23803
Query: 600 ALTAAG 605
A A G
Sbjct: 23804 ACNAGG 23809
Score = 35.4 bits (80), Expect = 0.23
Identities = 46/192 (23%), Positives = 83/192 (43%), Gaps = 12/192 (6%)
Query: 423 APRQVSANSEGMDNILVTWQPPRKDPSAVQEYVVEWRELHPGGDTQVPLNWLRSRPYNVS 482
AP + +++LV W P+ + S + Y +E RE++ ++V + L + NV
Sbjct: 8600 APDKPIVEDVTSNSMLVKWNEPKDNGSPILGYWLEKREVNSTHWSRVNKSLLNALKANVD 8659
Query: 483 ALISENIKSYICYEIRVYALSGDQGGCSSILGNSK-HKAPLS--GPHINAITEEKG-SIL 538
L+ + Y RV A + G S + K P+S GP I +T+ +I
Sbjct: 8660 GLLEG-----LTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIPRVTDTSSTTIE 8714
Query: 539 ISWNSIPVQEQMGCLLHYRIYWKERDSNSQPQLCEIPYRVSQNSHPINSLQPRVTYVLWM 598
+ W P G ++ Y + + +N + E +V Q + + ++ Y L +
Sbjct: 8715 LEWEP-PAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQ--YTVKEIREGADYKLRV 8771
Query: 599 TALTAAGESSHG 610
+A+ AAGE G
Sbjct: 8772 SAVNAAGEGPPG 8783
Score = 35.4 bits (80), Expect = 0.23
Identities = 47/201 (23%), Positives = 79/201 (39%), Gaps = 25/201 (12%)
Query: 423 APRQVSANSEGMDNILVTWQPPRKD-PSAVQEYVVEWRELHPGGDTQVPLNWLRSRPYNV 481
AP+ + D+++V W+ P D S + YV+E R+ T+ + V
Sbjct: 16434 APKAPEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRV 16493
Query: 482 SALISENIKSYICYEIRVYA-----------LSGDQGGCSSILGNSKHKAPLSGPHINAI 530
+ LI + YE RV A S Q C I P + P + I
Sbjct: 16494 TGLIENH-----DYEFRVSAENAAGLSEPSPPSAYQKACDPIY----KPGPPNNPKVIDI 16544
Query: 531 TEEKGSILISWNSIPVQEQMGCLLHYRIYWKERDSNSQPQLCEIPYRVSQNSHPINSLQP 590
T + S+ +SW S P+ + GC + I K S + +C P +++ + + L
Sbjct: 16545 T--RSSVFLSW-SKPIYDG-GCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLE 16600
Query: 591 RVTYVLWMTALTAAGESSHGN 611
+ Y + A+ AG H +
Sbjct: 16601 KHEYNFRICAINKAGVGEHAD 16621
Score = 35.4 bits (80), Expect = 0.23
Identities = 37/137 (27%), Positives = 61/137 (44%), Gaps = 12/137 (8%)
Query: 397 VSAANSKGSSLPTRINIMNLCEAGLL---APRQVSANSEGMDNILVTWQPPRKDPSA-VQ 452
VSA N+ G S P ++ + + ++ AP + + + D+ +V W+PP D A ++
Sbjct: 24493 VSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIR 24552
Query: 453 EYVVEWRELHPGGDTQVPLNWLRSRPYNVSALISENIKSYICYEIRVYALS-GDQGGCSS 511
Y +E RE V +R ++V LI E ++ YE RV + G + S
Sbjct: 24553 NYYLEKREKKQNKWISVTTEEIRETVFSVKNLI-EGLE----YEFRVKCENLGGESEWSE 24607
Query: 512 ILG--NSKHKAPLSGPH 526
I K P+ PH
Sbjct: 24608 ISEPITPKSDVPIQAPH 24624
Score = 34.7 bits (78), Expect = 0.39
Identities = 30/101 (29%), Positives = 49/101 (48%), Gaps = 9/101 (8%)
Query: 263 NSRLWNMVNVTKAKGR-HDLLDLKPFTEYEFQISSKLHLYKGSWSDWSESLRAQTPEEEP 321
NS LW VN + GR + L +Y+F++ ++ S SD S+ A +P +P
Sbjct: 21494 NSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSP-VDP 21552
Query: 322 TGMLDVWYMKRHIDYSRQQISLFWKNLSVSEARGKILHYQV 362
G D +ID +R+ I+L W N + + KI+ Y +
Sbjct: 21553 PGTPD------YIDVTRETITLKW-NPPLRDGGSKIVGYSI 21586
Score = 34.7 bits (78), Expect = 0.39
Identities = 43/213 (20%), Positives = 81/213 (38%), Gaps = 9/213 (4%)
Query: 140 TVACTWERGRDT--HLYTEYTLQLSGPKNLTWQKQCKDIYCDYLDFGINLTPESPESNFT 197
++ TW R +Y L+ K+ W K F + E E F
Sbjct: 21862 SITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFH 21921
Query: 198 AKVTAVNSLGSSSSLPSTFTFLDIVRPLPPWDIRIKFQKASVSRCTLYWR----DEGLVL 253
+G +S + + V P P + +K S + +L W D G+ +
Sbjct: 21922 VMAENAAGVGPASGISRLIKCREPVNPPGPPTV-VKVTDTSKTTVSLEWSKPVFDGGMEI 21980
Query: 254 LNRL-RYRPSNSRLWNMVNVTKA-KGRHDLLDLKPFTEYEFQISSKLHLYKGSWSDWSES 311
+ + ++ W+ VN K R+ + DL+ EY+F++S+ KG + + +
Sbjct: 21981 IGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGT 22040
Query: 312 LRAQTPEEEPTGMLDVWYMKRHIDYSRQQISLF 344
++A P +D + + H+ + I LF
Sbjct: 22041 IKAVDRLTAPELDIDANFKQTHVVRAGASIRLF 22073
Score = 33.5 bits (75), Expect = 0.87
Identities = 30/119 (25%), Positives = 56/119 (47%), Gaps = 7/119 (5%)
Query: 427 VSANSEGMDNILVTWQPPRKD-PSAVQEYVVEWRELHPGGDTQVPLNWLRSR-PYNVSAL 484
VS + D ++++W+PP D S + Y++E +E+ G D +P+ ++ VS L
Sbjct: 10614 VSFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEV--GKDVWMPVTSASAKTTCKVSKL 10671
Query: 485 ISENIKSYICYEIRVYALSGDQGGCSSILGNSKHKAPLSGPHINAITE-EKGSILISWN 542
+ + + +Y +S D S+ + + P P +TE K S L++WN
Sbjct: 10672 LEGKDYIFRIHAENLYGIS-DPLVSDSMKAKDRFRVP-DAPDQPIVTEVTKDSALVTWN 10728
Score = 33.1 bits (74), Expect = 1.1
Identities = 52/221 (23%), Positives = 94/221 (42%), Gaps = 22/221 (9%)
Query: 200 VTAVNSLGSSSSLPSTFTFLDIVRPLPPWDIRIKFQKASVSRCTLYWR----DEGLVLLN 255
+T N LGS+++ + I P P DI K + S C L W D G +L+
Sbjct: 8154 ITLENKLGSATA---SINVKVIGLPGPCKDI--KASDITKSSCKLTWEPPEFDGGTPILH 8208
Query: 256 R-LRYRPSNSRLWNMVNVTKAKGRHDLLDLKPFTEYEFQISSKLHLYKGSWSDWSESLRA 314
L R + R + V + K + DL P EY F++ + + G + + + A
Sbjct: 8209 YVLERREAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIA 8268
Query: 315 QTPEEEPTGMLDVWYMKRHIDYSRQQISLFWKNLSVSEARGKILHYQVTLQELTGGKAMT 374
Q P++ P +DV + H + + + +++ WK + + KI+ Y ++++ G+
Sbjct: 8269 QDPKQPPDPPVDV---EVH-NPTAEAMTITWKP-PLYDGGSKIMGY--IIEKIAKGEERW 8321
Query: 375 QNITGH-----TSWTTVIPRTGNWAVAVSAANSKGSSLPTR 410
+ H T + + V A N+ G S P+R
Sbjct: 8322 KRCNEHLVPILTYTAKGLEEGKEYQFRVRAENAAGISEPSR 8362
Score = 30.8 bits (68), Expect = 5.6
Identities = 71/354 (20%), Positives = 136/354 (38%), Gaps = 31/354 (8%)
Query: 124 PEQPQNLSCIQKGEQGTVACTWERGR--DTHLYTEYTLQLSGPKNLTWQKQCKDIYCDYL 181
P P N++ G V+ TWE T Y ++L ++ W + + L
Sbjct: 6886 PGPPLNVTITDVNRFG-VSLTWEPPEYDGGAEITNYVIELRDKTSIRWDT-AMTVRAEDL 6943
Query: 182 DFGINLTPESPESNFTAKVTAVNSLG---SSSSLPSTFTFLDIVRPLPPWDIRIKFQKAS 238
+ E E +F +V A N +G S++ P I RP PP + + +
Sbjct: 6944 SATVTDVVEGQEYSF--RVRAQNRIGVGKPSAATPFVKVADPIERPSPP--VNLTSSDQT 6999
Query: 239 VSRCTLYW----RDEGLVLLNRLRYRPSNSR-LWNMVNVTKAKG-RHDLLDLKPFTEYEF 292
S L W +D G +L + R + W N+ + + L+ +Y +
Sbjct: 7000 QSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLY 7059
Query: 293 QISSKLHLYKGSWSDWSESLRAQTPEE---EPTGMLDVWYMKRHIDYS-RQQISLFWKNL 348
++S++ K SD SE L T ++ EPT +D+ K ++ I++ +
Sbjct: 7060 RVSAE---NKAGVSDPSEILGPLTADDAFVEPT--MDLSAFKDGLEVIVPNPITILVPST 7114
Query: 349 SVSEARGKILHYQVTLQELTGGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLP 408
L+ TG + + ++ + + + ++ ++
Sbjct: 7115 GYPRPTATWCFGDKVLE--TGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTIS 7172
Query: 409 TRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKD-PSAVQEYVVEWREL 461
I++ + AP+++ D++ +TW+PP D S + YVVE RE+
Sbjct: 7173 GEIDVNVIARPS--APKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREV 7224
Score = 30.4 bits (67), Expect = 7.4
Identities = 45/205 (21%), Positives = 78/205 (38%), Gaps = 27/205 (13%)
Query: 155 TEYTLQLSGPKNLTWQK---QCKDIYCDYLDFGINLTPESPESNFTAKVTAVNSLGSSSS 211
T Y ++ + WQ KD C +TP + S + +V A N++G S
Sbjct: 7811 TNYIVEKRDVRRKGWQTVDTTVKDTKC-------TVTPLTEGSLYVFRVAAENAIGQSDY 7863
Query: 212 LPSTFTFL---DIVRPLPPWDIRIKFQKASVSRCTLYW---RDEGLVLLNRLRYRPSNSR 265
+ L P PP+ + + + L W +++G + R
Sbjct: 7864 TEIEDSVLAKDTFTTPGPPYALAVV--DVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERL 7921
Query: 266 LWNMVNVTKAKG---RHDLLDLKPFTEYEFQISSKLHLYKGSWSDWSESLRAQTPEEEPT 322
V K G + D+ TE +FQ+ ++ G S+ +E L + P P+
Sbjct: 7922 GTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPS 7981
Query: 323 GMLDVWYMKRHI-DYSRQQISLFWK 346
LD+ H+ D R+ I++ WK
Sbjct: 7982 PPLDL-----HVTDAGRKHIAIAWK 8001
Score = 30.4 bits (67), Expect = 7.4
Identities = 24/81 (29%), Positives = 36/81 (44%), Gaps = 6/81 (7%)
Query: 424 PRQVSANSEGMDNILVTWQPPRKD-PSAVQEYVVEWRELHPGGDTQVPLNWLRSRPYNVS 482
P + + + +TW PP+ D S + YV+E R + +V + L SR Y V
Sbjct: 10415 PEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVK 10474
Query: 483 ALISENIKSYICYEIRVYALS 503
L K YE RV A++
Sbjct: 10475 GL-----KEGDTYEYRVSAVN 10490
Score = 30.4 bits (67), Expect = 7.4
Identities = 58/287 (20%), Positives = 110/287 (38%), Gaps = 33/287 (11%)
Query: 232 IKFQKASVSRCTLYWRDE----GLVLLNRL-RYRPSNSRLWNMVNVTKAKGRHDLLDLKP 286
I+ S C L W + G + N + R S + W +VN + + + + L
Sbjct: 22443 IEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTK 22502
Query: 287 FTEYEFQISSKLHLYKGSWSDWSESLRAQTPEEEPTGML--DVWYMKRHIDYSRQQISLF 344
+ EY F++SS+ + + S S + A+ P P+ +V+++ S +S+
Sbjct: 22503 YMEYSFRVSSE-NRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHV------SANAMSIR 22555
Query: 345 WKNLSVSEARGKILHYQVTLQELTGGKAMTQNITGHTSW---TTVIPRTGNWAVAVSAAN 401
W+ + KI+ Y V +E + +N T + + A N
Sbjct: 22556 WEE-PYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALN 22614
Query: 402 SKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKD-PSAVQEYVVEWRE 460
+ G S + + + + + AP + + + W P D S V Y++E +
Sbjct: 22615 AAGVSKASEASRPIMAQNPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKP 22674
Query: 461 LHPGGDTQVPLNWLRSRPYNVSALISENIKSYIC------YEIRVYA 501
+ GD + WL+ ++S+N + YE RV A
Sbjct: 22675 VSEVGDGR----WLKCN----YTIVSDNFFTVTALSEGDTYEFRVLA 22713
Score = 30.0 bits (66), Expect = 9.6
Identities = 55/255 (21%), Positives = 92/255 (36%), Gaps = 28/255 (10%)
Query: 124 PEQPQNLSCIQKGEQGTVACTWERGRDTH--LYTEYTLQLSGPKNLTWQKQCKDIYCDYL 181
P +NL + C W+ D Y L+ K + W + L
Sbjct: 11992 PGPVRNLKIVDVSSDRCTVC-WDPPEDDGGCEIQNYILEKCETKRMVWSTYSATV----L 12046
Query: 182 DFGINLTPESPESNFTAKVTAVNSLGSSSSLPSTFTFLDIV-----RPLPPWDIRIKFQK 236
G +T + + +V A N +G+ S RP PP + K
Sbjct: 12047 TPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAKTKYDKPGRPDPP-----EVTK 12101
Query: 237 ASVSRCTLYWR----DEGLVLLNR-LRYRPSNSRLWNMVNVTKAKGRH-DLLDLKPFTEY 290
S T+ W D G + L + +S W VN + R + +L P EY
Sbjct: 12102 VSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEY 12161
Query: 291 EFQISSKLHLYKGSWSDWSESLRAQTPEEEPTGMLDVWYMKRHIDYSRQQISLFWKNLSV 350
+F++ ++ + G S S + A+ P E P + R +D ++ I+L W V
Sbjct: 12162 QFRVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNF----RVVDTTKHSITLGW-GKPV 12216
Query: 351 SEARGKILHYQVTLQ 365
+ I+ Y V ++
Sbjct: 12217 YDGGAPIIGYVVEMR 12231
Score = 30.0 bits (66), Expect = 9.6
Identities = 38/175 (21%), Positives = 68/175 (38%), Gaps = 21/175 (12%)
Query: 456 VEWRELHPGGDTQVPLNWLRSRPYNVSALISEN-------------IKSYICYEIRVYAL 502
+ W E + G +++ W+ + N + EN + + Y+ R YAL
Sbjct: 22554 IRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYAL 22613
Query: 503 SGDQGGCSSILGNSKH---KAPLSGPHINAITE-EKGSILISWNSIPVQEQMGCLLHYRI 558
+ G S S+ + P+ P +T+ + ++ + W S P + ++ Y I
Sbjct: 22614 NA--AGVSKASEASRPIMAQNPVDAPGRPEVTDVTRSTVSLIW-SAPAYDGGSKVVGYII 22670
Query: 559 YWKERDSNSQPQLCEIPYR-VSQNSHPINSLQPRVTYVLWMTALTAAGESSHGNE 612
K + + Y VS N + +L TY + A AAG S G+E
Sbjct: 22671 ERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSE 22725
>gi|110349713 titin isoform novex-1 [Homo sapiens]
Length = 27051
Score = 56.2 bits (134), Expect = 1e-07
Identities = 73/311 (23%), Positives = 133/311 (42%), Gaps = 24/311 (7%)
Query: 200 VTAVNSLGSSSSLPSTFTFLDIVRPLPPWDIRIKFQKASVSRCTLYWRDE----GLVLLN 255
VTA NS G+++ + + + +P PP ++F + S + W G + N
Sbjct: 18012 VTATNSAGTATE---NLSVIVLEKPGPPVG-PVRFDEVSADFVVISWEPPAYTGGCQISN 18067
Query: 256 RL-RYRPSNSRLWNMVNVTKAKGRHDLLDLKPFTEYEFQISSKLHLYKGSWSDWSESLRA 314
+ R + + W+MV+ T A+ + LK TEY+F+I ++ K + D S+++
Sbjct: 18068 YIVEKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAPLD-SKAVIV 18126
Query: 315 QTPEEEPTGMLDVWYMKRHIDYSRQQISLFWKNLSVSEARGKILHYQVTLQE---LTGGK 371
Q P +EP G ++ S+ Q+ + W V++ KI+ Y + +E + K
Sbjct: 18127 QYPFKEP-GPPGTPFV---TSISKDQMLVQWHE-PVNDGGTKIIGYHLEQKEKNSILWVK 18181
Query: 372 AMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANS 431
I TT + + VSA N G P++++ + P + A
Sbjct: 18182 LNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAIV 18241
Query: 432 EGMDNILVTWQPPRKD-PSAVQEYVVEWRELHPGGDTQVPLNWLRSRPYNVSALISENIK 490
+N+ + W+ P D S + Y+VE ++L G + + + VS L+ +
Sbjct: 18242 ITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQ-- 18299
Query: 491 SYICYEIRVYA 501
YE RV A
Sbjct: 18300 ---RYEFRVIA 18307
Score = 52.0 bits (123), Expect = 2e-06
Identities = 77/334 (23%), Positives = 133/334 (39%), Gaps = 27/334 (8%)
Query: 183 FGINLTPESPESNFTAKVTAVNS---LGSSSSLPSTFTFLDIV---RPLPPWDIRIKFQK 236
F +T E+ N VTA + +++S +T F++IV RP PP +
Sbjct: 20151 FNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTG-PVVISD 20209
Query: 237 ASVSRCTLYWR----DEGLVLLNR-LRYRPSNSRLWNMVNVTKAKGRHDLLDLKPFTEYE 291
+ TL W D G + N L R +++ +W V+ T A+ ++ L EY+
Sbjct: 20210 ITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQ 20269
Query: 292 FQISSKLHLYKGSWSDWSESLRAQTPEEEPTGMLDVWYMKRHIDYSRQQISLFWKNLSVS 351
F+I ++ D S + + P P W + +R+ I++ W VS
Sbjct: 20270 FRIKAENRFGISDHID-SACVTVKLPYTTPGPPSTPWV----TNVTRESITVGWHE-PVS 20323
Query: 352 EARGKILHYQVTLQE---LTGGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLP 408
++ Y + +++ + KA I T I + V A N+ G P
Sbjct: 20324 NGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGVGKP 20383
Query: 409 TRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKD-PSAVQEYVVEWRELHPGGDT 467
+ + L PR V +++ ++WQ P D S + Y+VE R+L G T
Sbjct: 20384 SHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWT 20443
Query: 468 QVPLNWLRSRPYNVSALISENIKSYICYEIRVYA 501
+ + + +S L + YE RV+A
Sbjct: 20444 KASFTNVTETQFIISGLTQNS-----QYEFRVFA 20472
Score = 48.5 bits (114), Expect = 3e-05
Identities = 69/312 (22%), Positives = 130/312 (41%), Gaps = 29/312 (9%)
Query: 203 VNSLGSSSSLPSTFTFLDIVRPLPPWDIRIKFQKASVSRCTLYWR----DEGLVLLNRL- 257
V S+ T + + +P PP +K + + TL W D G + N +
Sbjct: 15848 VKLTNSAGEAIETLNVIVLDKPGPPTG-PVKMDEVTADSITLSWGPPKYDGGSSINNYIV 15906
Query: 258 RYRPSNSRLWNMVNVTKAKGRHDLLDLKPFTEYEFQISSKLHLYKGSWSDWSESLRAQTP 317
R +++ W +V+ T A+ LK EY+F+I+++ K ++ + SE AQ P
Sbjct: 15907 EKRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGKSTYLN-SEPTVAQYP 15965
Query: 318 EEEP----TGMLDVWYMKRHIDYSRQQISLFWKNLSVSEARGKILHYQVTLQELTGGKAM 373
+ P T ++ + SR + + W N +S+ +++ Y + +E +
Sbjct: 15966 FKVPGPPGTPVVTL--------SSRDSMEVQW-NEPISDGGSRVIGYHLERKERNSILWV 16016
Query: 374 TQNIT--GHTSW-TTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSAN 430
N T T + TT + + VSA N G P++++ + P + A
Sbjct: 16017 KLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAI 16076
Query: 431 SEGMDNILVTWQPPRKD-PSAVQEYVVEWRELHPGGDTQVPLNWLRSRPYNVSALISENI 489
+++ + W+ P D S + Y+VE +EL G + + + V+ L+ ++
Sbjct: 16077 IVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDH- 16135
Query: 490 KSYICYEIRVYA 501
YE RV A
Sbjct: 16136 ----RYEFRVIA 16143
Score = 46.2 bits (108), Expect = 1e-04
Identities = 76/334 (22%), Positives = 137/334 (41%), Gaps = 41/334 (12%)
Query: 185 INLTPESPESNFTAKVTAVNSLGSSSSLPSTFTFLDIVRPLPPWDIRIKFQKASVSRCTL 244
+++ S E T ++ NS GS + +P T LD RP PP IRI + S T+
Sbjct: 19080 LSIKEASKEDVGTYELCVSNSAGSIT-VPITIIVLD--RPGPPGPIRI--DEVSCDSITI 19134
Query: 245 YWR----DEGLVLLNRL-RYRPSNSRLWNMVNVTKAKGRHDLLDLKPFTEYEFQISSKLH 299
W D G + N + + + S W++V+ A+ ++ L +EY+F++ ++
Sbjct: 19135 SWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENR 19194
Query: 300 LYKGSWSDWSESLRAQTP--EEEPTGMLDVWYMKRHIDYSRQQISLFWKNLSVSEARGKI 357
K S+S+ S ++ A+ P P G V + ++ + + W+ + V++ ++
Sbjct: 19195 YGKSSYSE-SSAVVAEYPFSPPGPPGTPKV------VHATKSTMLVTWQ-VPVNDGGSRV 19246
Query: 358 LHYQVTLQE---LTGGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKG----SSLPTR 410
+ Y + +E + KA I + + + V A N G S
Sbjct: 19247 IGYHLEYKERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEP 19306
Query: 411 INIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKDPSA-VQEYVVEWRELHPGGDTQV 469
+ + C+ P Q + ++ + W P D A + Y+VE REL G
Sbjct: 19307 VPARDPCD----PPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDG----- 19357
Query: 470 PLNWLRSRPYNVSALISE--NIKSYICYEIRVYA 501
WL+ N+ E + YE RV+A
Sbjct: 19358 --RWLKCNYTNIQETYFEVTELTEDQRYEFRVFA 19389
Score = 42.4 bits (98), Expect = 0.002
Identities = 34/127 (26%), Positives = 64/127 (50%), Gaps = 10/127 (7%)
Query: 200 VTAVNSLGSSSSLPSTFTFLDIVRPLPPWDIRIKFQKASVSRCTLYWRDE----GLVLLN 255
+T N +G ++ + + + +P PP +KF S TL W G + N
Sbjct: 16930 ITVANVVGQKTA---SIEIVTLDKPDPPKG-PVKFDDVSAESITLSWNPPLYTGGCQITN 16985
Query: 256 RL-RYRPSNSRLWNMVNVTKAKGRHDLLDLKPFTEYEFQISSKLHLYKGSWSDWSESLRA 314
+ + R + + +W++V+ T A+ + LK TEY+F+I ++ + Y S++ S+ + A
Sbjct: 16986 YIVQKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFAE-NRYGQSFALESDPIVA 17044
Query: 315 QTPEEEP 321
Q P +EP
Sbjct: 17045 QYPYKEP 17051
Score = 40.8 bits (94), Expect = 0.005
Identities = 56/231 (24%), Positives = 103/231 (44%), Gaps = 19/231 (8%)
Query: 200 VTAVNSLGSSSSLPSTFTFLDIVRPLPPWDIRIKFQKASVSRCTLYWR----DEGLVLLN 255
+T NS GS S+ + LD P PP D+++K + + + TL W D G + N
Sbjct: 15559 LTVENSSGSKSAFVNV-RVLDT--PGPPQDLKVK--EVTKTSVTLTWDPPLLDGGSKIKN 15613
Query: 256 RL-RYRPSNSRLWNMVNVTKAKGRHDLLDLKPFTEYEFQISSKLHLYKGSWSDWSESLRA 314
+ R S + ++ V K + L+ Y F++ ++ G ++ +ES++A
Sbjct: 15614 YIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKA 15673
Query: 315 QTPEEEPTGMLDVWYMKRHIDYSRQQISLFWKNLSVSEARGKILHYQVTLQELTGGKAMT 374
+ P G + + +D +R +SL W+ + +IL Y V +Q K T
Sbjct: 15674 -SERPLPPGKITL------MDVTRNSVSLSWEKPE-HDGGSRILGYIVEMQTKGSDKWAT 15725
Query: 375 QNITGHTSWT-TVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAP 424
T T T + + ++ VSA N KG S P ++++ + + ++ P
Sbjct: 15726 CATVKVTEATITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKDLVIPP 15776
Score = 39.7 bits (91), Expect = 0.012
Identities = 81/353 (22%), Positives = 136/353 (38%), Gaps = 33/353 (9%)
Query: 127 PQNLSCIQKGEQGTVACTWER-----GRDTHLYTEYTLQLSGPKNLTWQKQCKDIYCDYL 181
P + + K + ++ W R G D + Y L+ K+L W K K+ D
Sbjct: 20696 PPGIPEVTKITKNSMTVVWSRPIADGGSDI---SGYFLEKRDKKSLGWFKVLKETIRDTR 20752
Query: 182 DFGINLTPESPESNFTAKVTAVNSLGSSS-SLPSTFTFL--DIVRPLPPWDIRIKFQKAS 238
LT S ++ +V AVN+ G S PS F I P PP IRI ++
Sbjct: 20753 QKVTGLTENS---DYQYRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIA--DST 20807
Query: 239 VSRCTLYWR----DEGLVLLNRL-RYRPSNSRLWNMVNVTKAKGR---HDLLDLKPFTEY 290
S TL W D G + + R W V+ TK + R + + +LKP Y
Sbjct: 20808 KSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVS-TKGEVRTTEYVVSNLKPGVNY 20866
Query: 291 EFQISSKLHLYKGSWSDWSESLRAQTPEEEPTGMLDVWYMKRHIDYSRQQISLFWKNLSV 350
F++S+ +G + +E ++A+ E P LDV I + + + + +
Sbjct: 20867 YFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQVL---IPF 20923
Query: 351 SEARGKILHYQVTLQELTGGKAMTQNITGHTSWTTV--IPRTGNWAVAVSAANSKGSSLP 408
+ ++ + L + T +S T+ + R ++ N G
Sbjct: 20924 KGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKS 20983
Query: 409 TRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKD-PSAVQEYVVEWRE 460
+ +++ L QV S G + + W PP D S + YV+E R+
Sbjct: 20984 STVSVKVLDTPAACQKLQVKHVSRG--TVTLLWDPPLIDGGSPIINYVIEKRD 21034
Score = 38.1 bits (87), Expect = 0.035
Identities = 74/344 (21%), Positives = 116/344 (33%), Gaps = 53/344 (15%)
Query: 182 DFGINLTPESPESNFTAKVTAVNSLGSSSSLPSTFTFLDIVRPLPPWDIRIKFQKASVSR 241
+F + E+ E F +G + L +I+ P P D+ +K + R
Sbjct: 12189 EFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEP-PEIDLDASMRKLVIVR 12247
Query: 242 CTLYWRDEGLVLLNRLRYRPSNSRLWNMVNVTKA--KGRHDLLDLKPFTEYEFQISSKLH 299
R L +R RP+ W V + KG+ DL+D F
Sbjct: 12248 AGCPIR-----LFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMAFL----------- 12291
Query: 300 LYKGSWSDWSESLRAQTPEEEPTGMLDVWYMKRHIDYSRQQISLFWKNLSVSEARGKILH 359
+ S D +S + P G V+ R +D +L VS+ H
Sbjct: 12292 VIPNSTRD--DSGKYSLTLVNPAGEKAVFVNVRVLDTPGPV-----SDLKVSDVTKTSCH 12344
Query: 360 YQVTLQELTGGKAMTQNIT-----GHTSWTTVIPRT------------GN-WAVAVSAAN 401
E GG +T I +W+TV P GN + V+A N
Sbjct: 12345 VSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVN 12404
Query: 402 SKGSSLPTRINIMNLCEAGLLAP---RQVSANSEGMDNILVTWQPPRKDPSA-VQEYVVE 457
G +PT + L L P R++ ++ + W PP +D A + Y+
Sbjct: 12405 EYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITS 12464
Query: 458 WRELHPGGDTQVPLNWLRSRPYNVSALISENIKSYICYEIRVYA 501
+RE D W +L+ +K Y+ RV A
Sbjct: 12465 YREEEQPAD-----RWTEYSVVKDLSLVVTGLKEGKKYKFRVAA 12503
Score = 37.7 bits (86), Expect = 0.046
Identities = 43/183 (23%), Positives = 74/183 (40%), Gaps = 18/183 (9%)
Query: 124 PEQPQNLSCIQKGEQGTVACTWERGRDT--HLYTEYTLQLSGPKNLTWQKQCKDIYCDYL 181
PE P N + + +V+ +W R +D T Y ++ W + K +
Sbjct: 23957 PEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTM 24016
Query: 182 DFGINLTPESPESNFTAKVTAVNSLGSSSSLPSTFTFL---DIVRPLPPWDIRI-KFQKA 237
+T P++ + ++ A N +G S + P++ + +P P ++ I K
Sbjct: 24017 ---YTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKD 24073
Query: 238 SVSRCTLYWR----DEGLVLLNR-LRYRPSNSRLWNMVNVTKAKGRHDLL-DLKPFTEYE 291
SV TL W D G +L + YR S W N + K + + L TEYE
Sbjct: 24074 SV---TLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYE 24130
Query: 292 FQI 294
F++
Sbjct: 24131 FRV 24133
Score = 37.4 bits (85), Expect = 0.060
Identities = 90/379 (23%), Positives = 149/379 (39%), Gaps = 44/379 (11%)
Query: 196 FTAKVTAVNSLGSSSSLPSTFTFL---DIVRPLPP-WDIRIKFQKASVS-RCTLYWRDEG 250
++ +V AVN G S + L + P PP W I K + + T+ +D G
Sbjct: 7681 YSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGG 7740
Query: 251 LVLLNRL-RYRPSNSRLWNMVNVTKAKGRHDLLDLKPFTEYEFQISSKLHLYKGSWSDWS 309
+ N + R + W V+ T + + L + Y F+++++ + + +++
Sbjct: 7741 SPITNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIE 7800
Query: 310 ESLRAQ---TPEEEPTGMLDVWYMKRHIDYSRQQISLFWKNLSVSEARGKILHYQVTLQE 366
+S+ A+ T P + V KRH+D L W+ R I Y + +E
Sbjct: 7801 DSVLAKDTFTTPGPPYALAVVDVTKRHVD-------LKWEPPKNDGGR-PIQRYVIEKKE 7852
Query: 367 LTGGKAMTQNITGHTSW----TTVIPRTGNWAVAVSAANSKG---SSLPTRINIMNLCEA 419
G + + T T VI T V A N G S PT I + +
Sbjct: 7853 RLGTRWVKAGKTAGPDCNFRVTDVIEGT-EVQFQVRAENEAGVGHPSEPTEILSIEDPTS 7911
Query: 420 GLLAPRQVSANSEGMDNILVTWQPPRKD-PSAVQEYVVEWRELHPGGDTQVPLNWLR--S 476
P + G +I + W+PP K+ S + Y V E+ P G + W+R S
Sbjct: 7912 PPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHV---EMCPVGTEK----WMRVNS 7964
Query: 477 RPY-NVSALISENIKSYICYEIRVYALSG-DQGGCSSILGNSKHKAPLSGPHIN------ 528
RP ++ + E + Y +RV A++ S I N K P P I+
Sbjct: 7965 RPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHDI 8024
Query: 529 -AITEEKGSILISWNSIPV 546
I EK SI + + ++PV
Sbjct: 8025 IVIEGEKLSIPVPFRAVPV 8043
Score = 36.6 bits (83), Expect = 0.10
Identities = 59/287 (20%), Positives = 108/287 (37%), Gaps = 25/287 (8%)
Query: 335 DYSRQQISLFWKNLSVSEARGKILHYQVTLQELTGGKAMTQNITGHTSWTTV----IPRT 390
+ ++ + + WK + + KI +Y + +E+ GK + +T ++ TT +
Sbjct: 10551 EVTKDYMVISWKP-PLDDGGSKITNYIIEKKEV--GKDVWMPVTSASAKTTCKVSKLLEG 10607
Query: 391 GNWAVAVSAANSKGSSLPTRINIMNLCEAGLL--APRQVSANSEGMDNILVTWQPPRKDP 448
++ + A N G S P + M + + AP Q D+ LVTW P
Sbjct: 10608 KDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGG 10667
Query: 449 SAVQEYVVEWRELHPGGDTQVPLNWLRSRPYNVSALISENIKSYI--C-YEIRVYALS-- 503
+ Y++E RE + W R + + + C YE RV A +
Sbjct: 10668 KPITNYILEKRE-------TMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEI 10720
Query: 504 --GDQGGCSS-ILGNSKHKAPLSGPHINAITEEKGSILISWNSIPVQEQMGCLLHYRIYW 560
GD S + P + AI S+ ++W P + +L Y + +
Sbjct: 10721 GIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQP-PRHDGGSKILGYIVEY 10779
Query: 561 KERDSNSQPQLCEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAGES 607
++ + P + + + L+ TY + A+ AAGES
Sbjct: 10780 QKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGES 10826
Score = 36.6 bits (83), Expect = 0.10
Identities = 52/217 (23%), Positives = 91/217 (41%), Gaps = 23/217 (10%)
Query: 397 VSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKD-PSAVQEYV 455
++A NS GS T I + L + G P V N D +++W+PP +D S + Y+
Sbjct: 12996 ITAENSSGSKSAT-IKLKVLDKPG--PPASVKINKMYSDRAMLSWEPPLEDGGSEITNYI 13052
Query: 456 VEWRELHPGGDTQVPLNWLR-SRPYNVSALISENIKSYICYEIRVYALS----GDQGGCS 510
V+ RE T P NW + S +++ E + Y+ R+ A + GD
Sbjct: 13053 VDKRE------TSRP-NWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTE 13105
Query: 511 SILGNSKHKAP--LSGPHINAITEEKGSILISWNSIPVQEQMGCLLHYRIYWKERDSNSQ 568
+ + + P P I+ IT K + +SW P + + Y + +E + +
Sbjct: 13106 PAIAKNPYDPPGRCDPPVISNIT--KDHMTVSWKP-PADDGGSPITGYLLEKRETQAVNW 13162
Query: 569 PQLCEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAG 605
++ P + + + LQ Y +TA+ AG
Sbjct: 13163 TKVNRKP--IIERTLKATGLQEGTEYEFRVTAINKAG 13197
Score = 36.6 bits (83), Expect = 0.10
Identities = 41/176 (23%), Positives = 71/176 (40%), Gaps = 9/176 (5%)
Query: 391 GNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKDPSA 450
G + + VS NS GS + I I+ L G P + + D+I ++W PP D
Sbjct: 19091 GTYELCVS--NSAGS-ITVPITIIVLDRPG--PPGPIRIDEVSCDSITISWNPPEYDGGC 19145
Query: 451 -VQEYVVEWRELHPGGDTQVPLNWLRSRPYNVSALISENIKSYICYEIRVYALSGDQGGC 509
+ Y+VE +E V R+ V + +C E R S +
Sbjct: 19146 QISNYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSES-- 19203
Query: 510 SSILGNSKHKAPLSGPHINAITEEKGSILISWNSIPVQEQMGCLLHYRIYWKERDS 565
S+++ P + K ++L++W +PV + ++ Y + +KER S
Sbjct: 19204 SAVVAEYPFSPPGPPGTPKVVHATKSTMLVTW-QVPVNDGGSRVIGYHLEYKERSS 19258
Score = 36.6 bits (83), Expect = 0.10
Identities = 68/306 (22%), Positives = 116/306 (37%), Gaps = 59/306 (19%)
Query: 164 PKNLTWQKQCKDIYCDY------LDFGINLTPESPESNFTAK--VTAVNSLGSSSSLPST 215
P +TW+K K++ D D LT N T K +T N +G S +
Sbjct: 20928 PPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVS 20987
Query: 216 FTFLDIVRPLPPWDIRIKFQKASVSRCTLYWR----DEGLVLLNR-LRYRPSNSRLWNMV 270
LD P +++ + S TL W D G ++N + R + R W++V
Sbjct: 20988 VKVLDT----PAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVV 21043
Query: 271 NVTKAKGRHDLLDLKPFTEYEFQISSKLHLYKGSWSDWSESLRAQTPEEEPTGMLDVWYM 330
+ + L+DL T + F++ ++ + G + +E ++A E P + D+ M
Sbjct: 21044 SHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKA---AEVPAPIRDL-SM 21099
Query: 331 KRHIDYSRQQISLFWKNLSVSEARGKILHYQVTLQELTGGKAMTQNITGHTSWTTVIPRT 390
K D ++ + L W T + GG +T+ V+ R
Sbjct: 21100 K---DSTKTSVILSW-----------------TKPDFDGGSVITE---------YVVERK 21130
Query: 391 GNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKDPSA 450
G S A G S I + L E +L R + N +G+ + P P
Sbjct: 21131 GKGEQTWSHA---GISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSD------PVTIGPIT 21181
Query: 451 VQEYVV 456
V+E ++
Sbjct: 21182 VKELII 21187
Score = 36.2 bits (82), Expect = 0.13
Identities = 76/327 (23%), Positives = 120/327 (36%), Gaps = 50/327 (15%)
Query: 164 PKNLTWQKQCKDIYCDYLDFGINLTPESPESNFTAK-----------VTAVNSLGSSSSL 212
PK+ +W K KDI + I TP S S T K +TA N G+
Sbjct: 14037 PKS-SWSKAGKDIRPSDIT-QITSTPTS--SMLTIKYATRKDAGEYTITATNPFGTKVEH 14092
Query: 213 PSTFTFLDIVRPLPPWDIRIKFQKASVSRCTLYW----RDEGLVLLNRLRYRPSNSRL-W 267
T LD+ P PP + I S + TL W D G + + + + SRL W
Sbjct: 14093 VKV-TVLDV--PGPPGPVEIS--NVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLW 14147
Query: 268 NMVNVTKAKGRHDLLDLKPFTEYEFQISSKLHLYKGSWSDWSESLRAQTPEEEPTGMLDV 327
+V+ RH L EY F++S+ H KG + + EP M+D
Sbjct: 14148 TVVSEDIQSCRHVATKLIQGNEYIFRVSAVNHYGKG-----------EPVQSEPVKMVDR 14196
Query: 328 W------YMKRHIDYSRQQISLFWKNLSVSEARGKILHYQVTLQE---LTGGKAMTQNIT 378
+ + ++ ++ WK V + +I Y V +E L +A+ ++
Sbjct: 14197 FGPPGPPEKPEVSNVTKNTATVSWKR-PVDDGGSEITGYHVERREKKSLRWVRAIKTPVS 14255
Query: 379 GHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAPRQVS---ANSEGMD 435
T + + VSA N G P+ + L + P S
Sbjct: 14256 DLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKK 14315
Query: 436 NILVTWQPPRKDPS-AVQEYVVEWREL 461
+ + W P D + YVVE +++
Sbjct: 14316 SASLAWGKPHYDGGLEITGYVVEHQKV 14342
Score = 35.8 bits (81), Expect = 0.18
Identities = 42/195 (21%), Positives = 85/195 (43%), Gaps = 21/195 (10%)
Query: 289 EYEFQISSKLHLYKGSWSDWSESLRAQTPEEEPTGMLDVWYMKRHIDYSRQQISLFWKNL 348
EY F++S++ + G + + A++ + P L+V D +R +SL W+
Sbjct: 6787 EYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTIT----DVNRFGVSLTWEPP 6842
Query: 349 SVSEARGKILHYQVTLQELTGGK---AMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGS 405
+ +I +Y + L++ T + AMT ++ T + ++ V A N G
Sbjct: 6843 EY-DGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGV 6901
Query: 406 SLPTR----INIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKD-PSAVQEYVVEWRE 460
P+ + + + E P ++++ + ++ + W+PP KD S + Y++E
Sbjct: 6902 GKPSAATPFVKVADPIERPS-PPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYIIE--R 6958
Query: 461 LHPGGDTQVPLNWLR 475
G D NW+R
Sbjct: 6959 CEEGKD-----NWIR 6968
Score = 35.8 bits (81), Expect = 0.18
Identities = 62/283 (21%), Positives = 112/283 (39%), Gaps = 28/283 (9%)
Query: 339 QQISLFWKNLSVSEARGKILHYQVTLQELTG--GKAMTQNITGHTSWTTVIPRTGNWAVA 396
++I+L W+ + KI HY V +E + +++++ TT I + +
Sbjct: 20609 EKITLLWRP-PADDGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFR 20667
Query: 397 VSAANSKGSSLPTRINIMNLCEA-------GLLAPRQVSANSEGMDNILVTWQPPRKDP- 448
V A N G P + + A G+ +++ NS + V W P D
Sbjct: 20668 VRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNS-----MTVVWSRPIADGG 20722
Query: 449 SAVQEYVVEWRELHPGGDTQVPLNWLRSRPYNVSALISENIKSYICYEIRVYALSG-DQG 507
S + Y +E R+ G +V +R V+ L +EN Y+ RV A++ QG
Sbjct: 20723 SDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGL-TENSD----YQYRVCAVNAAGQG 20777
Query: 508 GCSSILGNSKHKAPLSGP----HINAITEEKGSILISWNSIPVQEQMGCLLHYRIYWKER 563
S K P+ P I K SI + W+ PV + + Y + ++
Sbjct: 20778 PFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSK-PVYDGGSAVTGYVVEIRQG 20836
Query: 564 DSNSQPQLCEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAGE 606
+ + V + +++L+P V Y ++A+ AG+
Sbjct: 20837 EEEEWTTV-STKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQ 20878
Score = 35.8 bits (81), Expect = 0.18
Identities = 53/246 (21%), Positives = 98/246 (39%), Gaps = 18/246 (7%)
Query: 369 GGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLAP---R 425
G +++++T T T + + V+A N G + ++ C + + P
Sbjct: 23506 GWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIGSYLQSEVIE-CRSSIRIPGPPE 23564
Query: 426 QVSANSEGMDNILVTWQPPRKD-PSAVQEYVVEWRELHPGGDTQVPLNWLRSRPYNVSAL 484
+ D + +TW PP D S V Y+VE +E+ D V +N + P ++
Sbjct: 23565 TLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVR--ADRWVRVNKV---PVTMTRY 23619
Query: 485 ISENIKSYICYEIRVYAL----SGDQGGCSSILGNSKHKAPLSGPHINAITE-EKGSILI 539
S + + YE RV A+ SG S + AP P +T+ + S+ +
Sbjct: 23620 RSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSL 23679
Query: 540 SWNSIPVQEQMGCLLHYRIYWKERDSNSQPQLCEIPYRVSQNSHPINSLQPRVTYVLWMT 599
+W S+P E + Y I ++ D + + P ++ + + + L Y +
Sbjct: 23680 AW-SVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIRE--YTLTHLPQGAEYRFRVL 23736
Query: 600 ALTAAG 605
A A G
Sbjct: 23737 ACNAGG 23742
Score = 35.4 bits (80), Expect = 0.23
Identities = 46/192 (23%), Positives = 83/192 (43%), Gaps = 12/192 (6%)
Query: 423 APRQVSANSEGMDNILVTWQPPRKDPSAVQEYVVEWRELHPGGDTQVPLNWLRSRPYNVS 482
AP + +++LV W P+ + S + Y +E RE++ ++V + L + NV
Sbjct: 8533 APDKPIVEDVTSNSMLVKWNEPKDNGSPILGYWLEKREVNSTHWSRVNKSLLNALKANVD 8592
Query: 483 ALISENIKSYICYEIRVYALSGDQGGCSSILGNSK-HKAPLS--GPHINAITEEKG-SIL 538
L+ + Y RV A + G S + K P+S GP I +T+ +I
Sbjct: 8593 GLLEG-----LTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIPRVTDTSSTTIE 8647
Query: 539 ISWNSIPVQEQMGCLLHYRIYWKERDSNSQPQLCEIPYRVSQNSHPINSLQPRVTYVLWM 598
+ W P G ++ Y + + +N + E +V Q + + ++ Y L +
Sbjct: 8648 LEWEP-PAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQ--YTVKEIREGADYKLRV 8704
Query: 599 TALTAAGESSHG 610
+A+ AAGE G
Sbjct: 8705 SAVNAAGEGPPG 8716
Score = 35.4 bits (80), Expect = 0.23
Identities = 47/201 (23%), Positives = 79/201 (39%), Gaps = 25/201 (12%)
Query: 423 APRQVSANSEGMDNILVTWQPPRKD-PSAVQEYVVEWRELHPGGDTQVPLNWLRSRPYNV 481
AP+ + D+++V W+ P D S + YV+E R+ T+ + V
Sbjct: 16367 APKAPEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRV 16426
Query: 482 SALISENIKSYICYEIRVYA-----------LSGDQGGCSSILGNSKHKAPLSGPHINAI 530
+ LI + YE RV A S Q C I P + P + I
Sbjct: 16427 TGLIENH-----DYEFRVSAENAAGLSEPSPPSAYQKACDPIY----KPGPPNNPKVIDI 16477
Query: 531 TEEKGSILISWNSIPVQEQMGCLLHYRIYWKERDSNSQPQLCEIPYRVSQNSHPINSLQP 590
T + S+ +SW S P+ + GC + I K S + +C P +++ + + L
Sbjct: 16478 T--RSSVFLSW-SKPIYDG-GCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLE 16533
Query: 591 RVTYVLWMTALTAAGESSHGN 611
+ Y + A+ AG H +
Sbjct: 16534 KHEYNFRICAINKAGVGEHAD 16554
Score = 35.4 bits (80), Expect = 0.23
Identities = 37/137 (27%), Positives = 61/137 (44%), Gaps = 12/137 (8%)
Query: 397 VSAANSKGSSLPTRINIMNLCEAGLL---APRQVSANSEGMDNILVTWQPPRKDPSA-VQ 452
VSA N+ G S P ++ + + ++ AP + + + D+ +V W+PP D A ++
Sbjct: 24426 VSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIR 24485
Query: 453 EYVVEWRELHPGGDTQVPLNWLRSRPYNVSALISENIKSYICYEIRVYALS-GDQGGCSS 511
Y +E RE V +R ++V LI E ++ YE RV + G + S
Sbjct: 24486 NYYLEKREKKQNKWISVTTEEIRETVFSVKNLI-EGLE----YEFRVKCENLGGESEWSE 24540
Query: 512 ILG--NSKHKAPLSGPH 526
I K P+ PH
Sbjct: 24541 ISEPITPKSDVPIQAPH 24557
Score = 34.7 bits (78), Expect = 0.39
Identities = 30/101 (29%), Positives = 49/101 (48%), Gaps = 9/101 (8%)
Query: 263 NSRLWNMVNVTKAKGR-HDLLDLKPFTEYEFQISSKLHLYKGSWSDWSESLRAQTPEEEP 321
NS LW VN + GR + L +Y+F++ ++ S SD S+ A +P +P
Sbjct: 21427 NSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSP-VDP 21485
Query: 322 TGMLDVWYMKRHIDYSRQQISLFWKNLSVSEARGKILHYQV 362
G D +ID +R+ I+L W N + + KI+ Y +
Sbjct: 21486 PGTPD------YIDVTRETITLKW-NPPLRDGGSKIVGYSI 21519
Score = 34.7 bits (78), Expect = 0.39
Identities = 43/213 (20%), Positives = 81/213 (38%), Gaps = 9/213 (4%)
Query: 140 TVACTWERGRDT--HLYTEYTLQLSGPKNLTWQKQCKDIYCDYLDFGINLTPESPESNFT 197
++ TW R +Y L+ K+ W K F + E E F
Sbjct: 21795 SITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFH 21854
Query: 198 AKVTAVNSLGSSSSLPSTFTFLDIVRPLPPWDIRIKFQKASVSRCTLYWR----DEGLVL 253
+G +S + + V P P + +K S + +L W D G+ +
Sbjct: 21855 VMAENAAGVGPASGISRLIKCREPVNPPGPPTV-VKVTDTSKTTVSLEWSKPVFDGGMEI 21913
Query: 254 LNRL-RYRPSNSRLWNMVNVTKA-KGRHDLLDLKPFTEYEFQISSKLHLYKGSWSDWSES 311
+ + ++ W+ VN K R+ + DL+ EY+F++S+ KG + + +
Sbjct: 21914 IGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGT 21973
Query: 312 LRAQTPEEEPTGMLDVWYMKRHIDYSRQQISLF 344
++A P +D + + H+ + I LF
Sbjct: 21974 IKAVDRLTAPELDIDANFKQTHVVRAGASIRLF 22006
Score = 33.5 bits (75), Expect = 0.87
Identities = 30/119 (25%), Positives = 56/119 (47%), Gaps = 7/119 (5%)
Query: 427 VSANSEGMDNILVTWQPPRKD-PSAVQEYVVEWRELHPGGDTQVPLNWLRSR-PYNVSAL 484
VS + D ++++W+PP D S + Y++E +E+ G D +P+ ++ VS L
Sbjct: 10547 VSFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEV--GKDVWMPVTSASAKTTCKVSKL 10604
Query: 485 ISENIKSYICYEIRVYALSGDQGGCSSILGNSKHKAPLSGPHINAITE-EKGSILISWN 542
+ + + +Y +S D S+ + + P P +TE K S L++WN
Sbjct: 10605 LEGKDYIFRIHAENLYGIS-DPLVSDSMKAKDRFRVP-DAPDQPIVTEVTKDSALVTWN 10661
Score = 33.1 bits (74), Expect = 1.1
Identities = 52/221 (23%), Positives = 94/221 (42%), Gaps = 22/221 (9%)
Query: 200 VTAVNSLGSSSSLPSTFTFLDIVRPLPPWDIRIKFQKASVSRCTLYWR----DEGLVLLN 255
+T N LGS+++ + I P P DI K + S C L W D G +L+
Sbjct: 8087 ITLENKLGSATA---SINVKVIGLPGPCKDI--KASDITKSSCKLTWEPPEFDGGTPILH 8141
Query: 256 R-LRYRPSNSRLWNMVNVTKAKGRHDLLDLKPFTEYEFQISSKLHLYKGSWSDWSESLRA 314
L R + R + V + K + DL P EY F++ + + G + + + A
Sbjct: 8142 YVLERREAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIA 8201
Query: 315 QTPEEEPTGMLDVWYMKRHIDYSRQQISLFWKNLSVSEARGKILHYQVTLQELTGGKAMT 374
Q P++ P +DV + H + + + +++ WK + + KI+ Y ++++ G+
Sbjct: 8202 QDPKQPPDPPVDV---EVH-NPTAEAMTITWKP-PLYDGGSKIMGY--IIEKIAKGEERW 8254
Query: 375 QNITGH-----TSWTTVIPRTGNWAVAVSAANSKGSSLPTR 410
+ H T + + V A N+ G S P+R
Sbjct: 8255 KRCNEHLVPILTYTAKGLEEGKEYQFRVRAENAAGISEPSR 8295
Score = 30.8 bits (68), Expect = 5.6
Identities = 71/354 (20%), Positives = 136/354 (38%), Gaps = 31/354 (8%)
Query: 124 PEQPQNLSCIQKGEQGTVACTWERGR--DTHLYTEYTLQLSGPKNLTWQKQCKDIYCDYL 181
P P N++ G V+ TWE T Y ++L ++ W + + L
Sbjct: 6819 PGPPLNVTITDVNRFG-VSLTWEPPEYDGGAEITNYVIELRDKTSIRWDT-AMTVRAEDL 6876
Query: 182 DFGINLTPESPESNFTAKVTAVNSLG---SSSSLPSTFTFLDIVRPLPPWDIRIKFQKAS 238
+ E E +F +V A N +G S++ P I RP PP + + +
Sbjct: 6877 SATVTDVVEGQEYSF--RVRAQNRIGVGKPSAATPFVKVADPIERPSPP--VNLTSSDQT 6932
Query: 239 VSRCTLYW----RDEGLVLLNRLRYRPSNSR-LWNMVNVTKAKG-RHDLLDLKPFTEYEF 292
S L W +D G +L + R + W N+ + + L+ +Y +
Sbjct: 6933 QSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLY 6992
Query: 293 QISSKLHLYKGSWSDWSESLRAQTPEE---EPTGMLDVWYMKRHIDYS-RQQISLFWKNL 348
++S++ K SD SE L T ++ EPT +D+ K ++ I++ +
Sbjct: 6993 RVSAE---NKAGVSDPSEILGPLTADDAFVEPT--MDLSAFKDGLEVIVPNPITILVPST 7047
Query: 349 SVSEARGKILHYQVTLQELTGGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLP 408
L+ TG + + ++ + + + ++ ++
Sbjct: 7048 GYPRPTATWCFGDKVLE--TGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTIS 7105
Query: 409 TRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKD-PSAVQEYVVEWREL 461
I++ + AP+++ D++ +TW+PP D S + YVVE RE+
Sbjct: 7106 GEIDVNVIARPS--APKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREV 7157
Score = 30.4 bits (67), Expect = 7.4
Identities = 45/205 (21%), Positives = 78/205 (38%), Gaps = 27/205 (13%)
Query: 155 TEYTLQLSGPKNLTWQK---QCKDIYCDYLDFGINLTPESPESNFTAKVTAVNSLGSSSS 211
T Y ++ + WQ KD C +TP + S + +V A N++G S
Sbjct: 7744 TNYIVEKRDVRRKGWQTVDTTVKDTKC-------TVTPLTEGSLYVFRVAAENAIGQSDY 7796
Query: 212 LPSTFTFL---DIVRPLPPWDIRIKFQKASVSRCTLYW---RDEGLVLLNRLRYRPSNSR 265
+ L P PP+ + + + L W +++G + R
Sbjct: 7797 TEIEDSVLAKDTFTTPGPPYALAVV--DVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERL 7854
Query: 266 LWNMVNVTKAKG---RHDLLDLKPFTEYEFQISSKLHLYKGSWSDWSESLRAQTPEEEPT 322
V K G + D+ TE +FQ+ ++ G S+ +E L + P P+
Sbjct: 7855 GTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPS 7914
Query: 323 GMLDVWYMKRHI-DYSRQQISLFWK 346
LD+ H+ D R+ I++ WK
Sbjct: 7915 PPLDL-----HVTDAGRKHIAIAWK 7934
Score = 30.4 bits (67), Expect = 7.4
Identities = 24/81 (29%), Positives = 36/81 (44%), Gaps = 6/81 (7%)
Query: 424 PRQVSANSEGMDNILVTWQPPRKD-PSAVQEYVVEWRELHPGGDTQVPLNWLRSRPYNVS 482
P + + + +TW PP+ D S + YV+E R + +V + L SR Y V
Sbjct: 10348 PEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVK 10407
Query: 483 ALISENIKSYICYEIRVYALS 503
L K YE RV A++
Sbjct: 10408 GL-----KEGDTYEYRVSAVN 10423
Score = 30.4 bits (67), Expect = 7.4
Identities = 58/287 (20%), Positives = 110/287 (38%), Gaps = 33/287 (11%)
Query: 232 IKFQKASVSRCTLYWRDE----GLVLLNRL-RYRPSNSRLWNMVNVTKAKGRHDLLDLKP 286
I+ S C L W + G + N + R S + W +VN + + + + L
Sbjct: 22376 IEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTK 22435
Query: 287 FTEYEFQISSKLHLYKGSWSDWSESLRAQTPEEEPTGML--DVWYMKRHIDYSRQQISLF 344
+ EY F++SS+ + + S S + A+ P P+ +V+++ S +S+
Sbjct: 22436 YMEYSFRVSSE-NRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHV------SANAMSIR 22488
Query: 345 WKNLSVSEARGKILHYQVTLQELTGGKAMTQNITGHTSW---TTVIPRTGNWAVAVSAAN 401
W+ + KI+ Y V +E + +N T + + A N
Sbjct: 22489 WEE-PYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALN 22547
Query: 402 SKGSSLPTRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKD-PSAVQEYVVEWRE 460
+ G S + + + + + AP + + + W P D S V Y++E +
Sbjct: 22548 AAGVSKASEASRPIMAQNPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKP 22607
Query: 461 LHPGGDTQVPLNWLRSRPYNVSALISENIKSYIC------YEIRVYA 501
+ GD + WL+ ++S+N + YE RV A
Sbjct: 22608 VSEVGDGR----WLKCN----YTIVSDNFFTVTALSEGDTYEFRVLA 22646
Score = 30.0 bits (66), Expect = 9.6
Identities = 55/255 (21%), Positives = 92/255 (36%), Gaps = 28/255 (10%)
Query: 124 PEQPQNLSCIQKGEQGTVACTWERGRDTH--LYTEYTLQLSGPKNLTWQKQCKDIYCDYL 181
P +NL + C W+ D Y L+ K + W + L
Sbjct: 11925 PGPVRNLKIVDVSSDRCTVC-WDPPEDDGGCEIQNYILEKCETKRMVWSTYSATV----L 11979
Query: 182 DFGINLTPESPESNFTAKVTAVNSLGSSSSLPSTFTFLDIV-----RPLPPWDIRIKFQK 236
G +T + + +V A N +G+ S RP PP + K
Sbjct: 11980 TPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAKTKYDKPGRPDPP-----EVTK 12034
Query: 237 ASVSRCTLYWR----DEGLVLLNR-LRYRPSNSRLWNMVNVTKAKGRH-DLLDLKPFTEY 290
S T+ W D G + L + +S W VN + R + +L P EY
Sbjct: 12035 VSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEY 12094
Query: 291 EFQISSKLHLYKGSWSDWSESLRAQTPEEEPTGMLDVWYMKRHIDYSRQQISLFWKNLSV 350
+F++ ++ + G S S + A+ P E P + R +D ++ I+L W V
Sbjct: 12095 QFRVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNF----RVVDTTKHSITLGW-GKPV 12149
Query: 351 SEARGKILHYQVTLQ 365
+ I+ Y V ++
Sbjct: 12150 YDGGAPIIGYVVEMR 12164
Score = 30.0 bits (66), Expect = 9.6
Identities = 38/175 (21%), Positives = 68/175 (38%), Gaps = 21/175 (12%)
Query: 456 VEWRELHPGGDTQVPLNWLRSRPYNVSALISEN-------------IKSYICYEIRVYAL 502
+ W E + G +++ W+ + N + EN + + Y+ R YAL
Sbjct: 22487 IRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYAL 22546
Query: 503 SGDQGGCSSILGNSKH---KAPLSGPHINAITE-EKGSILISWNSIPVQEQMGCLLHYRI 558
+ G S S+ + P+ P +T+ + ++ + W S P + ++ Y I
Sbjct: 22547 NA--AGVSKASEASRPIMAQNPVDAPGRPEVTDVTRSTVSLIW-SAPAYDGGSKVVGYII 22603
Query: 559 YWKERDSNSQPQLCEIPYR-VSQNSHPINSLQPRVTYVLWMTALTAAGESSHGNE 612
K + + Y VS N + +L TY + A AAG S G+E
Sbjct: 22604 ERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSE 22658
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.134 0.424
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,012,986
Number of Sequences: 37866
Number of extensions: 1900721
Number of successful extensions: 5594
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 124
Number of HSP's that attempted gapping in prelim test: 4801
Number of HSP's gapped (non-prelim): 704
length of query: 862
length of database: 18,247,518
effective HSP length: 111
effective length of query: 751
effective length of database: 14,044,392
effective search space: 10547338392
effective search space used: 10547338392
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.