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Search of human proteins with 4503595
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4503595 eosinophil peroxidase [Homo sapiens]
(715 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4503595 eosinophil peroxidase [Homo sapiens] 1451 0.0
gi|4557759 myeloperoxidase [Homo sapiens] 1030 0.0
gi|40549418 lactoperoxidase isoform 1 preproprotein [Homo sapiens] 727 0.0
gi|231569458 lactoperoxidase isoform 3 preproprotein [Homo sapiens] 693 0.0
gi|28558982 thyroid peroxidase isoform a [Homo sapiens] 596 e-170
gi|28558988 thyroid peroxidase isoform d [Homo sapiens] 596 e-170
gi|109150416 peroxidasin [Homo sapiens] 517 e-146
gi|28558984 thyroid peroxidase isoform b [Homo sapiens] 508 e-143
gi|126517478 peroxidasin homolog-like [Homo sapiens] 450 e-126
gi|28558990 thyroid peroxidase isoform e [Homo sapiens] 292 8e-79
gi|20149640 dual oxidase 1 precursor [Homo sapiens] 139 7e-33
gi|28872751 dual oxidase 1 precursor [Homo sapiens] 139 7e-33
gi|132566532 dual oxidase 2 precursor [Homo sapiens] 124 3e-28
gi|18104967 prostaglandin-endoperoxide synthase 1 isoform 1 prec... 39 0.022
gi|4506265 prostaglandin-endoperoxide synthase 2 precursor [Homo... 37 0.049
gi|18104969 prostaglandin-endoperoxide synthase 1 isoform 2 prec... 36 0.11
gi|96975023 ankyrin repeat and death domain containing 1A [Homo ... 32 1.6
gi|4557665 insulin-like growth factor 1 receptor precursor [Homo... 31 3.5
gi|239755538 PREDICTED: hypothetical protein [Homo sapiens] 31 4.6
gi|239749994 PREDICTED: hypothetical protein XP_002347233 [Homo ... 31 4.6
gi|239744305 PREDICTED: hypothetical protein XP_002343094 [Homo ... 31 4.6
gi|148612875 RUN and TBC1 domain containing 2 isoform 4 [Homo sa... 30 6.0
gi|148612840 RUN and TBC1 domain containing 2 isoform 3 [Homo sa... 30 6.0
gi|90577164 RUN and TBC1 domain containing 2 isoform 2 [Homo sap... 30 7.8
gi|90577167 RUN and TBC1 domain containing 2 isoform 1 [Homo sap... 30 7.8
gi|4506763 S100 calcium binding protein A3 [Homo sapiens] 30 7.8
>gi|4503595 eosinophil peroxidase [Homo sapiens]
Length = 715
Score = 1451 bits (3757), Expect = 0.0
Identities = 715/715 (100%), Positives = 715/715 (100%)
Query: 1 MHLLPALAGVLATLVLAQPCEGTDPASPGAVETSVLRDCIAEAKLLVDAAYNWTQKSIKQ 60
MHLLPALAGVLATLVLAQPCEGTDPASPGAVETSVLRDCIAEAKLLVDAAYNWTQKSIKQ
Sbjct: 1 MHLLPALAGVLATLVLAQPCEGTDPASPGAVETSVLRDCIAEAKLLVDAAYNWTQKSIKQ 60
Query: 61 RLRSGSASPMDLLSYFKQPVAATRTVVRAADYMHVALGLLEEKLQPQRSGPFNVTDVLTE 120
RLRSGSASPMDLLSYFKQPVAATRTVVRAADYMHVALGLLEEKLQPQRSGPFNVTDVLTE
Sbjct: 61 RLRSGSASPMDLLSYFKQPVAATRTVVRAADYMHVALGLLEEKLQPQRSGPFNVTDVLTE 120
Query: 121 PQLRLLSQASGCALRDQAERCSDKYRTITGRCNNKRRPLLGASNQALARWLPAEYEDGLS 180
PQLRLLSQASGCALRDQAERCSDKYRTITGRCNNKRRPLLGASNQALARWLPAEYEDGLS
Sbjct: 121 PQLRLLSQASGCALRDQAERCSDKYRTITGRCNNKRRPLLGASNQALARWLPAEYEDGLS 180
Query: 181 LPFGWTPSRRRNGFLLPLVRAVSNQIVRFPNERLTSDRGRALMFMQWGQFIDHDLDFSPE 240
LPFGWTPSRRRNGFLLPLVRAVSNQIVRFPNERLTSDRGRALMFMQWGQFIDHDLDFSPE
Sbjct: 181 LPFGWTPSRRRNGFLLPLVRAVSNQIVRFPNERLTSDRGRALMFMQWGQFIDHDLDFSPE 240
Query: 241 SPARVAFTAGVDCERTCAQLPPCFPIKIPPNDPRIKNQRDCIPFFRSAPSCPQNKNRVRN 300
SPARVAFTAGVDCERTCAQLPPCFPIKIPPNDPRIKNQRDCIPFFRSAPSCPQNKNRVRN
Sbjct: 241 SPARVAFTAGVDCERTCAQLPPCFPIKIPPNDPRIKNQRDCIPFFRSAPSCPQNKNRVRN 300
Query: 301 QINALTSFVDASMVYGSEVSLSLRLRNRTNYLGLLAINQRFQDNGRALLPFDNLHDDPCL 360
QINALTSFVDASMVYGSEVSLSLRLRNRTNYLGLLAINQRFQDNGRALLPFDNLHDDPCL
Sbjct: 301 QINALTSFVDASMVYGSEVSLSLRLRNRTNYLGLLAINQRFQDNGRALLPFDNLHDDPCL 360
Query: 361 LTNRSARIPCFLAGDTRSTETPKLAAMHTLFMREHNRLATELRRLNPRWNGDKLYNEARK 420
LTNRSARIPCFLAGDTRSTETPKLAAMHTLFMREHNRLATELRRLNPRWNGDKLYNEARK
Sbjct: 361 LTNRSARIPCFLAGDTRSTETPKLAAMHTLFMREHNRLATELRRLNPRWNGDKLYNEARK 420
Query: 421 IMGAMVQIITYRDFLPLVLGKARARRTLGHYRGYCSNVDPRVANVFTLAFRFGHTMLQPF 480
IMGAMVQIITYRDFLPLVLGKARARRTLGHYRGYCSNVDPRVANVFTLAFRFGHTMLQPF
Sbjct: 421 IMGAMVQIITYRDFLPLVLGKARARRTLGHYRGYCSNVDPRVANVFTLAFRFGHTMLQPF 480
Query: 481 MFRLDSQYRASAPNSHVPLSSAFFASWRIVYEGGIDPILRGLMATPAKLNRQDAMLVDEL 540
MFRLDSQYRASAPNSHVPLSSAFFASWRIVYEGGIDPILRGLMATPAKLNRQDAMLVDEL
Sbjct: 481 MFRLDSQYRASAPNSHVPLSSAFFASWRIVYEGGIDPILRGLMATPAKLNRQDAMLVDEL 540
Query: 541 RDRLFRQVRRIGLDLAALNMQRSRDHGLPGYNAWRRFCGLSQPRNLAQLSRVLKNQDLAR 600
RDRLFRQVRRIGLDLAALNMQRSRDHGLPGYNAWRRFCGLSQPRNLAQLSRVLKNQDLAR
Sbjct: 541 RDRLFRQVRRIGLDLAALNMQRSRDHGLPGYNAWRRFCGLSQPRNLAQLSRVLKNQDLAR 600
Query: 601 KFLNLYGTPDNIDIWIGAIAEPLLPGARVGPLLACLFENQFRRARDGDRFWWQKRGVFTK 660
KFLNLYGTPDNIDIWIGAIAEPLLPGARVGPLLACLFENQFRRARDGDRFWWQKRGVFTK
Sbjct: 601 KFLNLYGTPDNIDIWIGAIAEPLLPGARVGPLLACLFENQFRRARDGDRFWWQKRGVFTK 660
Query: 661 RQRKALSRISLSRIICDNTGITTVSRDIFRANIYPRGFVNCSRIPRLNLSAWRGT 715
RQRKALSRISLSRIICDNTGITTVSRDIFRANIYPRGFVNCSRIPRLNLSAWRGT
Sbjct: 661 RQRKALSRISLSRIICDNTGITTVSRDIFRANIYPRGFVNCSRIPRLNLSAWRGT 715
>gi|4557759 myeloperoxidase [Homo sapiens]
Length = 745
Score = 1030 bits (2663), Expect = 0.0
Identities = 501/716 (69%), Positives = 582/716 (81%), Gaps = 3/716 (0%)
Query: 1 MHLLPALAGVLATLVLAQPCEGTDPASPGAVETSVLRDCIAEAKLLVDAAYNWTQKSIKQ 60
M LL ALAG+LA L QP EG PA G V+TS++ + EAK LVD AY ++SIKQ
Sbjct: 27 MKLLLALAGLLAILATPQPSEGAAPAVLGEVDTSLVLSSMEEAKQLVDKAYKERRESIKQ 86
Query: 61 RLRSGSASPMDLLSYFKQPVAATRTVVRAADYMHVALGLLEEKLQPQRSGPFNVTDVLTE 120
RLRSGSASPM+LLSYFKQPVAATRT VRAADY+HVAL LLE KL+ PFNVTDVLT
Sbjct: 87 RLRSGSASPMELLSYFKQPVAATRTAVRAADYLHVALDLLERKLRSLWRRPFNVTDVLTP 146
Query: 121 PQLRLLSQASGCALRDQAERC--SDKYRTITGRCNNKRRPLLGASNQALARWLPAEYEDG 178
QL +LS++SGCA +D C DKYRTITG CNN+R P LGASN+A RWLPAEYEDG
Sbjct: 147 AQLNVLSKSSGCAYQDVGVTCPEQDKYRTITGMCNNRRSPTLGASNRAFVRWLPAEYEDG 206
Query: 179 LSLPFGWTPSRRRNGFLLPLVRAVSNQIVRFPNERLTSDRGRALMFMQWGQFIDHDLDFS 238
SLP+GWTP +RNGF + L RAVSN+IVRFP ++LT D+ R+LMFMQWGQ +DHDLDF+
Sbjct: 207 FSLPYGWTPGVKRNGFPVALARAVSNEIVRFPTDQLTPDQERSLMFMQWGQLLDHDLDFT 266
Query: 239 PESPARVAFTAGVDCERTCAQLPPCFPIKIPPNDPRIKNQRDCIPFFRSAPSCPQNKNRV 298
PE AR +F GV+CE +C Q PPCFP+KIPPNDPRIKNQ DCIPFFRS P+CP + +
Sbjct: 267 PEPAARASFVTGVNCETSCVQQPPCFPLKIPPNDPRIKNQADCIPFFRSCPACPGSNITI 326
Query: 299 RNQINALTSFVDASMVYGSEVSLSLRLRNRTNYLGLLAINQRFQDNGRALLPFDNLHDDP 358
RNQINALTSFVDASMVYGSE L+ LRN +N LGLLA+NQRFQDNGRALLPFDNLHDDP
Sbjct: 327 RNQINALTSFVDASMVYGSEEPLARNLRNMSNQLGLLAVNQRFQDNGRALLPFDNLHDDP 386
Query: 359 CLLTNRSARIPCFLAGDTRSTETPKLAAMHTLFMREHNRLATELRRLNPRWNGDKLYNEA 418
CLLTNRSARIPCFLAGDTRS+E P+L +MHTL +REHNRLATEL+ LNPRW+G++LY EA
Sbjct: 387 CLLTNRSARIPCFLAGDTRSSEMPELTSMHTLLLREHNRLATELKSLNPRWDGERLYQEA 446
Query: 419 RKIMGAMVQIITYRDFLPLVLGKARARRTLGHYRGYCSNVDPRVANVFTLAFRFGHTMLQ 478
RKI+GAMVQIITYRD+LPLVLG R+ L YR Y +VDPR+ANVFT AFR+GHT++Q
Sbjct: 447 RKIVGAMVQIITYRDYLPLVLGPTAMRKYLPTYRSYNDSVDPRIANVFTNAFRYGHTLIQ 506
Query: 479 PFMFRLDSQYRASAPNSHVPLSSAFFASWRIVYEGGIDPILRGLMATPAKLNRQDAMLVD 538
PFMFRLD++Y+ PN VPLS FFASWR+V EGGIDPILRGLMATPAKLNRQ+ + VD
Sbjct: 507 PFMFRLDNRYQPMEPNPRVPLSRVFFASWRVVLEGGIDPILRGLMATPAKLNRQNQIAVD 566
Query: 539 ELRDRLFRQVRRIGLDLAALNMQRSRDHGLPGYNAWRRFCGLSQPRNLAQLSRVLKNQDL 598
E+R+RLF QV RIGLDL ALNMQRSRDHGLPGYNAWRRFCGL QP + QL VL+N L
Sbjct: 567 EIRERLFEQVMRIGLDLPALNMQRSRDHGLPGYNAWRRFCGLPQPETVGQLGTVLRNLKL 626
Query: 599 ARKFLNLYGTPDNIDIWIGAIAEPLLPGARVGPLLACLFENQFRRARDGDRFWWQKRGVF 658
ARK + YGTP+NIDIW+G ++EPL RVGPLLAC+ QFR+ RDGDRFWW+ GVF
Sbjct: 627 ARKLMEQYGTPNNIDIWMGGVSEPLKRKGRVGPLLACIIGTQFRKLRDGDRFWWENEGVF 686
Query: 659 TKRQRKALSRISLSRIICDNTGITTVSR-DIFRANIYPRGFVNCSRIPRLNLSAWR 713
+ +QR+AL++ISL RIICDNTGITTVS+ +IF +N YPR FVNCS +P LNL++WR
Sbjct: 687 SMQQRQALAQISLPRIICDNTGITTVSKNNIFMSNSYPRDFVNCSTLPALNLASWR 742
>gi|40549418 lactoperoxidase isoform 1 preproprotein [Homo sapiens]
Length = 712
Score = 727 bits (1877), Expect = 0.0
Identities = 373/719 (51%), Positives = 487/719 (67%), Gaps = 19/719 (2%)
Query: 1 MHLLPALAGVLATLVLAQPCEGTDPASPGAVETSVLRDCIAEAKLLVDAAYNWTQKSIKQ 60
M +L L +LA+L+L Q T A TS + D +++AK+ V+ A+ ++ +K
Sbjct: 1 MRVLLHLPALLASLILLQAAASTTRAQ--TTRTSAISDTVSQAKVQVNKAFLDSRTRLKT 58
Query: 61 RLRSGSASPMDLLSYFKQPVAATRTVVRAADYMHVALGLLEEKLQPQRSGPFNVTDVLTE 120
+ S + + L Y K TRT +R +L L +K ++T+V T+
Sbjct: 59 AMSSETPTSRQLSEYLKHAKGRTRTAIRNGQVWEESLKRLRQKA--------SLTNV-TD 109
Query: 121 PQLRL--LSQASGCALRDQAERCS--DKYRTITGRCNNKRRPLLGASNQALARWLPAEYE 176
P L L LS GC RC YRTITG CNN+R+P LGA+N+ALARWLPAEYE
Sbjct: 110 PSLDLTSLSLEVGCGAPAPVVRCDPCSPYRTITGDCNNRRKPALGAANRALARWLPAEYE 169
Query: 177 DGLSLPFGWTPSRRRNGFLLPLVRAVSNQIVRFPNERLTSDRGRALMFMQWGQFIDHDLD 236
DGLSLPFGWTP + RNGF LPL R VSN+IV + NE D+ R+L+FMQWGQ +DHDLD
Sbjct: 170 DGLSLPFGWTPGKTRNGFPLPLAREVSNKIVGYLNEEGVLDQNRSLLFMQWGQIVDHDLD 229
Query: 237 FSPESPARVAFTAGVDCERTCAQLPPCFPIKIPPNDPRIKNQRDCIPFFRSAPSCPQN-- 294
F+P++ + + C+ C Q CFPI PPNDP+ Q C+PFFR+ CP
Sbjct: 230 FAPDTELGSSEYSKAQCDEYCIQGDNCFPIMFPPNDPKAGTQGKCMPFFRAGFVCPTPPY 289
Query: 295 KNRVRNQINALTSFVDASMVYGSEVSLSLRLRNRTNYLGLLAINQRFQDNGRALLPFDNL 354
K+ R QINALTSF+DAS VY SE SL+ RLRN ++ LGL+A+NQ D+G LP+D+
Sbjct: 290 KSLAREQINALTSFLDASFVYSSEPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPYDSK 349
Query: 355 HDDPCLLTNRSARIPCFLAGDTRSTETPKLAAMHTLFMREHNRLATELRRLNPRWNGDKL 414
PC N +AR+PCFLAGD+R++E LA HTLF+REHNRLA EL+RLNP+W+G+KL
Sbjct: 350 KPSPCEFINTTARVPCFLAGDSRASEHILLATSHTLFLREHNRLARELKRLNPQWDGEKL 409
Query: 415 YNEARKIMGAMVQIITYRDFLPLVLGKARARRTLGHYRGYCSNVDPRVANVFTLAFRFGH 474
Y EARKI+GA VQIIT+RD+LP++LG ++ + Y+GY +VDPR++NVFT AFRFGH
Sbjct: 410 YQEARKILGAFVQIITFRDYLPILLGD-HMQKWIPPYQGYSESVDPRISNVFTFAFRFGH 468
Query: 475 TMLQPFMFRLDSQYRASAPNSHVPLSSAFFASWRIVYEGGIDPILRGLMATPAKLNRQDA 534
+ MFRLD Y+ P +PL + FF +WR+V +GGIDP++RGL+A +KL +Q+
Sbjct: 469 LEVPSSMFRLDENYQPWGPEPELPLHTLFFNTWRMVKDGGIDPLVRGLLAKKSKLMKQNK 528
Query: 535 MLVDELRDRLFRQVRRI-GLDLAALNMQRSRDHGLPGYNAWRRFCGLSQPRNLAQLSRVL 593
M+ ELR++LF+ RI G DLAA+N QR RDHG PGYN+WR FC LSQP+ L +L+ VL
Sbjct: 529 MMTGELRNKLFQPTHRIHGFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEELNTVL 588
Query: 594 KNQDLARKFLNLYGTPDNIDIWIGAIAEPLLPGARVGPLLACLFENQFRRARDGDRFWWQ 653
K++ LA+K L LYGTPDNIDIWIGAIAEPL+ RVGPLLACL QF++ RDGDRFWW+
Sbjct: 589 KSKMLAKKLLGLYGTPDNIDIWIGAIAEPLVERGRVGPLLACLLGKQFQQIRDGDRFWWE 648
Query: 654 KRGVFTKRQRKALSRISLSRIICDNTGITTVSRDIFRANIYPRGFVNCSRIPRLNLSAW 712
GVFT Q+ +L ++S SR++CDNT IT V RD F AN YP FV+CS I +L+LS W
Sbjct: 649 NPGVFTNEQKDSLQKMSFSRLVCDNTRITKVPRDPFWANSYPYDFVDCSAIDKLDLSPW 707
>gi|231569458 lactoperoxidase isoform 3 preproprotein [Homo sapiens]
Length = 629
Score = 693 bits (1789), Expect = 0.0
Identities = 341/600 (56%), Positives = 432/600 (72%), Gaps = 8/600 (1%)
Query: 120 EPQLRL--LSQASGCALRDQAERCS--DKYRTITGRCNNKRRPLLGASNQALARWLPAEY 175
+P L L LS GC RC YRTITG CNN+R+P LGA+N+ALARWLPAEY
Sbjct: 26 DPSLDLTSLSLEVGCGAPAPVVRCDPCSPYRTITGDCNNRRKPALGAANRALARWLPAEY 85
Query: 176 EDGLSLPFGWTPSRRRNGFLLPLVRAVSNQIVRFPNERLTSDRGRALMFMQWGQFIDHDL 235
EDGLSLPFGWTP + RNGF LPL R VSN+IV + NE D+ R+L+FMQWGQ +DHDL
Sbjct: 86 EDGLSLPFGWTPGKTRNGFPLPLAREVSNKIVGYLNEEGVLDQNRSLLFMQWGQIVDHDL 145
Query: 236 DFSPESPARVAFTAGVDCERTCAQLPPCFPIKIPPNDPRIKNQRDCIPFFRSAPSCPQN- 294
DF+P++ + + C+ C Q CFPI PPNDP+ Q C+PFFR+ CP
Sbjct: 146 DFAPDTELGSSEYSKAQCDEYCIQGDNCFPIMFPPNDPKAGTQGKCMPFFRAGFVCPTPP 205
Query: 295 -KNRVRNQINALTSFVDASMVYGSEVSLSLRLRNRTNYLGLLAINQRFQDNGRALLPFDN 353
K+ R QINALTSF+DAS VY SE SL+ RLRN ++ LGL+A+NQ D+G LP+D+
Sbjct: 206 YKSLAREQINALTSFLDASFVYSSEPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPYDS 265
Query: 354 LHDDPCLLTNRSARIPCFLAGDTRSTETPKLAAMHTLFMREHNRLATELRRLNPRWNGDK 413
PC N +AR+PCFLAGD+R++E LA HTLF+REHNRLA EL+RLNP+W+G+K
Sbjct: 266 KKPSPCEFINTTARVPCFLAGDSRASEHILLATSHTLFLREHNRLARELKRLNPQWDGEK 325
Query: 414 LYNEARKIMGAMVQIITYRDFLPLVLGKARARRTLGHYRGYCSNVDPRVANVFTLAFRFG 473
LY EARKI+GA VQIIT+RD+LP++LG ++ + Y+GY +VDPR++NVFT AFRFG
Sbjct: 326 LYQEARKILGAFVQIITFRDYLPILLGD-HMQKWIPPYQGYSESVDPRISNVFTFAFRFG 384
Query: 474 HTMLQPFMFRLDSQYRASAPNSHVPLSSAFFASWRIVYEGGIDPILRGLMATPAKLNRQD 533
H + MFRLD Y+ P +PL + FF +WR+V +GGIDP++RGL+A +KL +Q+
Sbjct: 385 HLEVPSSMFRLDENYQPWGPEPELPLHTLFFNTWRMVKDGGIDPLVRGLLAKKSKLMKQN 444
Query: 534 AMLVDELRDRLFRQVRRI-GLDLAALNMQRSRDHGLPGYNAWRRFCGLSQPRNLAQLSRV 592
M+ ELR++LF+ RI G DLAA+N QR RDHG PGYN+WR FC LSQP+ L +L+ V
Sbjct: 445 KMMTGELRNKLFQPTHRIHGFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEELNTV 504
Query: 593 LKNQDLARKFLNLYGTPDNIDIWIGAIAEPLLPGARVGPLLACLFENQFRRARDGDRFWW 652
LK++ LA+K L LYGTPDNIDIWIGAIAEPL+ RVGPLLACL QF++ RDGDRFWW
Sbjct: 505 LKSKMLAKKLLGLYGTPDNIDIWIGAIAEPLVERGRVGPLLACLLGKQFQQIRDGDRFWW 564
Query: 653 QKRGVFTKRQRKALSRISLSRIICDNTGITTVSRDIFRANIYPRGFVNCSRIPRLNLSAW 712
+ GVFT Q+ +L ++S SR++CDNT IT V RD F AN YP FV+CS I +L+LS W
Sbjct: 565 ENPGVFTNEQKDSLQKMSFSRLVCDNTRITKVPRDPFWANSYPYDFVDCSAIDKLDLSPW 624
>gi|28558982 thyroid peroxidase isoform a [Homo sapiens]
Length = 933
Score = 596 bits (1537), Expect = e-170
Identities = 314/708 (44%), Positives = 428/708 (60%), Gaps = 25/708 (3%)
Query: 29 GAVETSVLRDCIAEAKLLVDAA-YNWTQKSIKQRLRSGSASPMDLLSYFKQPVAATRTVV 87
G E S + + E+K LVD A Y Q+++K+R G SP LLS+ K P + +
Sbjct: 32 GKPEESRVSSVLEESKRLVDTAMYATMQRNLKKR---GILSPAQLLSFSKLPEPTSGVIA 88
Query: 88 RAADYMHVALGLLEEKLQPQRSGPFNVTDVLTEPQLRLLSQASGCALRDQAERC-----S 142
RAA+ M ++ ++ K+ + + TD L+E L +++ SGC +C +
Sbjct: 89 RAAEIMETSIQAMKRKVNLKTQQSQHPTDALSEDLLSIIANMSGCLPYMLPPKCPNTCLA 148
Query: 143 DKYRTITGRCNNKRRPLLGASNQALARWLPAEYEDGLSLPFGWTPSRRRNGFLLPLVRAV 202
+KYR ITG CNN+ P GASN ALARWLP YEDG S P GW P NGF LP VR V
Sbjct: 149 NKYRPITGACNNRDHPRWGASNTALARWLPPVYEDGFSQPRGWNPGFLYNGFPLPPVREV 208
Query: 203 SNQIVRFPNERLTSDRGRALMFMQWGQFIDHDLDFSPESPARVAFTAGVDCERTCAQLPP 262
+ +++ NE +T D + + M WGQ+IDHD+ F+P+S ++ AF G DC+ TC P
Sbjct: 209 TRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHDIAFTPQSTSKAAFGGGADCQMTCENQNP 268
Query: 263 CFPIKIPPNDPRIKNQRDCIPFFRSAPSCPQNKNRV----------RNQINALTSFVDAS 312
CFPI++P + R C+PF+RS+ +C R Q+N LTSF+DAS
Sbjct: 269 CFPIQLP-EEARPAAGTACLPFYRSSAACGTGDQGALFGNLSTANPRQQMNGLTSFLDAS 327
Query: 313 MVYGSEVSLSLRLRNRTNYLGLLAINQRFQDNGRALLPFDNLHDDPCLLTNRS----ARI 368
VYGS +L +LRN T+ GLL ++ R +D+GRA LPF R
Sbjct: 328 TVYGSSPALERQLRNWTSAEGLLRVHARLRDSGRAYLPFVPPRAPAACAPEPGIPGETRG 387
Query: 369 PCFLAGDTRSTETPKLAAMHTLFMREHNRLATELRRLNPRWNGDKLYNEARKIMGAMVQI 428
PCFLAGD R++E P L A+HTL++REHNRLA L+ LN W+ D +Y EARK++GA+ QI
Sbjct: 388 PCFLAGDGRASEVPSLTALHTLWLREHNRLAAALKALNAHWSADAVYQEARKVVGALHQI 447
Query: 429 ITYRDFLPLVLGKARARRTLGHYRGYCSNVDPRVANVF-TLAFRFGHTMLQPFMFRLDSQ 487
IT RD++P +LG ++ +G Y GY S +P V+NVF T AFRFGH + P + RLD+
Sbjct: 448 ITLRDYIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDAS 507
Query: 488 YRASAPNSHVPLSSAFFASWRIVYEGGIDPILRGLMATPAKLNRQDAMLVDELRDRLFRQ 547
++ + L AFF+ W ++ GG+DP++RGL+A PAKL QD ++ +EL +RLF
Sbjct: 508 FQEHPDLPGLWLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERLFVL 567
Query: 548 VRRIGLDLAALNMQRSRDHGLPGYNAWRRFCGLSQPRNLAQLSRVLKNQDLARKFLNLYG 607
LDLA++N+QR RDHGLPGYN WR FCGL + A LS + ++ +A K L+LY
Sbjct: 568 SNSSTLDLASINLQRGRDHGLPGYNEWREFCGLPRLETPADLSTAIASRSVADKILDLYK 627
Query: 608 TPDNIDIWIGAIAEPLLPGARVGPLLACLFENQFRRARDGDRFWWQKRGVFTKRQRKALS 667
PDNID+W+G +AE LP AR GPL ACL Q + RDGD FWW+ VFT QR+ L
Sbjct: 628 HPDNIDVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSHVFTDAQRRELE 687
Query: 668 RISLSRIICDNTGITTVSRDIFRANIYPRGFVNCSRIPRLNLSAWRGT 715
+ SLSR+ICDNTG+T V D F+ +P F +C I +NL AWR T
Sbjct: 688 KHSLSRVICDNTGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAWRET 735
>gi|28558988 thyroid peroxidase isoform d [Homo sapiens]
Length = 889
Score = 596 bits (1537), Expect = e-170
Identities = 314/708 (44%), Positives = 428/708 (60%), Gaps = 25/708 (3%)
Query: 29 GAVETSVLRDCIAEAKLLVDAA-YNWTQKSIKQRLRSGSASPMDLLSYFKQPVAATRTVV 87
G E S + + E+K LVD A Y Q+++K+R G SP LLS+ K P + +
Sbjct: 32 GKPEESRVSSVLEESKRLVDTAMYATMQRNLKKR---GILSPAQLLSFSKLPEPTSGVIA 88
Query: 88 RAADYMHVALGLLEEKLQPQRSGPFNVTDVLTEPQLRLLSQASGCALRDQAERC-----S 142
RAA+ M ++ ++ K+ + + TD L+E L +++ SGC +C +
Sbjct: 89 RAAEIMETSIQAMKRKVNLKTQQSQHPTDALSEDLLSIIANMSGCLPYMLPPKCPNTCLA 148
Query: 143 DKYRTITGRCNNKRRPLLGASNQALARWLPAEYEDGLSLPFGWTPSRRRNGFLLPLVRAV 202
+KYR ITG CNN+ P GASN ALARWLP YEDG S P GW P NGF LP VR V
Sbjct: 149 NKYRPITGACNNRDHPRWGASNTALARWLPPVYEDGFSQPRGWNPGFLYNGFPLPPVREV 208
Query: 203 SNQIVRFPNERLTSDRGRALMFMQWGQFIDHDLDFSPESPARVAFTAGVDCERTCAQLPP 262
+ +++ NE +T D + + M WGQ+IDHD+ F+P+S ++ AF G DC+ TC P
Sbjct: 209 TRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHDIAFTPQSTSKAAFGGGADCQMTCENQNP 268
Query: 263 CFPIKIPPNDPRIKNQRDCIPFFRSAPSCPQNKNRV----------RNQINALTSFVDAS 312
CFPI++P + R C+PF+RS+ +C R Q+N LTSF+DAS
Sbjct: 269 CFPIQLP-EEARPAAGTACLPFYRSSAACGTGDQGALFGNLSTANPRQQMNGLTSFLDAS 327
Query: 313 MVYGSEVSLSLRLRNRTNYLGLLAINQRFQDNGRALLPFDNLHDDPCLLTNRS----ARI 368
VYGS +L +LRN T+ GLL ++ R +D+GRA LPF R
Sbjct: 328 TVYGSSPALERQLRNWTSAEGLLRVHARLRDSGRAYLPFVPPRAPAACAPEPGIPGETRG 387
Query: 369 PCFLAGDTRSTETPKLAAMHTLFMREHNRLATELRRLNPRWNGDKLYNEARKIMGAMVQI 428
PCFLAGD R++E P L A+HTL++REHNRLA L+ LN W+ D +Y EARK++GA+ QI
Sbjct: 388 PCFLAGDGRASEVPSLTALHTLWLREHNRLAAALKALNAHWSADAVYQEARKVVGALHQI 447
Query: 429 ITYRDFLPLVLGKARARRTLGHYRGYCSNVDPRVANVF-TLAFRFGHTMLQPFMFRLDSQ 487
IT RD++P +LG ++ +G Y GY S +P V+NVF T AFRFGH + P + RLD+
Sbjct: 448 ITLRDYIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDAS 507
Query: 488 YRASAPNSHVPLSSAFFASWRIVYEGGIDPILRGLMATPAKLNRQDAMLVDELRDRLFRQ 547
++ + L AFF+ W ++ GG+DP++RGL+A PAKL QD ++ +EL +RLF
Sbjct: 508 FQEHPDLPGLWLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERLFVL 567
Query: 548 VRRIGLDLAALNMQRSRDHGLPGYNAWRRFCGLSQPRNLAQLSRVLKNQDLARKFLNLYG 607
LDLA++N+QR RDHGLPGYN WR FCGL + A LS + ++ +A K L+LY
Sbjct: 568 SNSSTLDLASINLQRGRDHGLPGYNEWREFCGLPRLETPADLSTAIASRSVADKILDLYK 627
Query: 608 TPDNIDIWIGAIAEPLLPGARVGPLLACLFENQFRRARDGDRFWWQKRGVFTKRQRKALS 667
PDNID+W+G +AE LP AR GPL ACL Q + RDGD FWW+ VFT QR+ L
Sbjct: 628 HPDNIDVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSHVFTDAQRRELE 687
Query: 668 RISLSRIICDNTGITTVSRDIFRANIYPRGFVNCSRIPRLNLSAWRGT 715
+ SLSR+ICDNTG+T V D F+ +P F +C I +NL AWR T
Sbjct: 688 KHSLSRVICDNTGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAWRET 735
>gi|109150416 peroxidasin [Homo sapiens]
Length = 1479
Score = 517 bits (1331), Expect = e-146
Identities = 288/694 (41%), Positives = 397/694 (57%), Gaps = 28/694 (4%)
Query: 40 IAEAKLLVDAAYNWTQKSIKQRLRSGSASPMDLLSYFKQPVAA-TRTVVRAADYMHVALG 98
I EA VD A N T+ + S SP DLL+ F+ P T RA + L
Sbjct: 628 IVEAIATVDRAINSTRTHL---FDSRPRSPNDLLALFRYPRDPYTVEQARAGEIFERTLQ 684
Query: 99 LLEEKLQPQRSGPFNVT-----DVLTEPQLRLLSQASGCALRDQAERCSD-----KYRTI 148
L++E +Q N T D+++ L L++ SGC + CSD KYRT
Sbjct: 685 LIQEHVQHGLMVDLNGTSYHYNDLVSPQYLNLIANLSGCTAHRRVNNCSDMCFHQKYRTH 744
Query: 149 TGRCNNKRRPLLGASNQALARWLPAEYEDGLSLPFGWTPSRRRNGFLLPLVRAVSNQIVR 208
G CNN + P+ GAS A R L + YE+G + P G P R NG LP+ R VS ++
Sbjct: 745 DGTCNNLQHPMWGASLTAFERLLKSVYENGFNTPRGINPHRLYNGHALPMPRLVSTTLIG 804
Query: 209 FPNERLTSDRGRALMFMQWGQFIDHDLDFSPESPARVAFTAGVDCERTCAQLPPCFPIKI 268
E +T D M MQWGQF+DHDLD + + ++ F+ G C C+ PPCF + I
Sbjct: 805 --TETVTPDEQFTHMLMQWGQFLDHDLDSTVVALSQARFSDGQHCSNVCSNDPPCFSVMI 862
Query: 269 PPNDPRIKNQRDCIPFFRSAPSCPQNKNRV-------RNQINALTSFVDASMVYGSEVSL 321
PPND R ++ C+ F RS+P C + R QIN LTS++DAS VYGS
Sbjct: 863 PPNDSRARSGARCMFFVRSSPVCGSGMTSLLMNSVYPREQINQLTSYIDASNVYGSTEHE 922
Query: 322 SLRLRNRTNYLGLLAINQRFQDNGRALLPFDNLHDDPCLLTNRSARIPCFLAGDTRSTET 381
+ +R+ ++ GLL Q +G+ LLPF C+ + IPCFLAGD R+ E
Sbjct: 923 ARSIRDLASHRGLLR-QGIVQRSGKPLLPFATGPPTECMRDENESPIPCFLAGDHRANEQ 981
Query: 382 PKLAAMHTLFMREHNRLATELRRLNPRWNGDKLYNEARKIMGAMVQIITYRDFLPLVLGK 441
L +MHTL+ REHNR+ATEL +LNP W+GD +Y E RKI+GA +Q ITY+ +LP +LG+
Sbjct: 982 LGLTSMHTLWFREHNRIATELLKLNPHWDGDTIYYETRKIVGAEIQHITYQHWLPKILGE 1041
Query: 442 ARARRTLGHYRGYCSNVDPRVANVF-TLAFRFGHTMLQPFMFRLDSQYRASAPNSHVPLS 500
RTLG Y GY ++ + N F T AFRFGHT++ P ++RLD ++ A + H+PL
Sbjct: 1042 V-GMRTLGEYHGYDPGINAGIFNAFATAAFRFGHTLVNPLLYRLDENFQPIAQD-HLPLH 1099
Query: 501 SAFFASWRIVYEGGIDPILRGLMATPAKLNRQDAMLVDELRDRLFRQVRRIGLDLAALNM 560
AFF+ +RIV EGGIDP+LRGL K+ +L EL +RLF + LDLAA+N+
Sbjct: 1100 KAFFSPFRIVNEGGIDPLLRGLFGVAGKMRVPSQLLNTELTERLFSMAHTVALDLAAINI 1159
Query: 561 QRSRDHGLPGYNAWRRFCGLSQPRNLAQLSRVLKNQDLARKFLNLYGTPDNIDIWIGAIA 620
QR RDHG+P Y+ +R +C LS L +KN ++ K LYG+ NID++ +
Sbjct: 1160 QRGRDHGIPPYHDYRVYCNLSAAHTFEDLKNEIKNPEIREKLKRLYGSTLNIDLFPALVV 1219
Query: 621 EPLLPGARVGPLLACLFENQFRRARDGDRFWWQKRGVFTKRQRKALSRISLSRIICDNT- 679
E L+PG+R+GP L CL QF+R RDGDR W++ GVF+ Q + + SL+RI+CDN
Sbjct: 1220 EDLVPGSRLGPTLMCLLSTQFKRLRDGDRLWYENPGVFSPAQLTQIKQTSLARILCDNAD 1279
Query: 680 GITTVSRDIFRANIYPRGFVNCSRIPRLNLSAWR 713
IT V D+FR +P G+ +C IPR++L W+
Sbjct: 1280 NITRVQSDVFRVAEFPHGYGSCDEIPRVDLRVWQ 1313
>gi|28558984 thyroid peroxidase isoform b [Homo sapiens]
Length = 876
Score = 508 bits (1307), Expect = e-143
Identities = 285/708 (40%), Positives = 387/708 (54%), Gaps = 82/708 (11%)
Query: 29 GAVETSVLRDCIAEAKLLVDAA-YNWTQKSIKQRLRSGSASPMDLLSYFKQPVAATRTVV 87
G E S + + E+K LVD A Y Q+++K+R G SP LLS+ K P + +
Sbjct: 32 GKPEESRVSSVLEESKRLVDTAMYATMQRNLKKR---GILSPAQLLSFSKLPEPTSGVIA 88
Query: 88 RAADYMHVALGLLEEKLQPQRSGPFNVTDVLTEPQLRLLSQASGCALRDQAERC-----S 142
RAA+ M ++ ++ K+ + + TD L+E L +++ SGC +C +
Sbjct: 89 RAAEIMETSIQAMKRKVNLKTQQSQHPTDALSEDLLSIIANMSGCLPYMLPPKCPNTCLA 148
Query: 143 DKYRTITGRCNNKRRPLLGASNQALARWLPAEYEDGLSLPFGWTPSRRRNGFLLPLVRAV 202
+KYR ITG CNN+ P GASN ALARWLP YEDG S P GW P NGF LP VR V
Sbjct: 149 NKYRPITGACNNRDHPRWGASNTALARWLPPVYEDGFSQPRGWNPGFLYNGFPLPPVREV 208
Query: 203 SNQIVRFPNERLTSDRGRALMFMQWGQFIDHDLDFSPESPARVAFTAGVDCERTCAQLPP 262
+ +++ NE +T D + + M WGQ+IDHD+ F+P+S ++ AF G DC+ TC P
Sbjct: 209 TRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHDIAFTPQSTSKAAFGGGADCQMTCENQNP 268
Query: 263 CFPIKIPPNDPRIKNQRDCIPFFRSAPSCPQNKNRV----------RNQINALTSFVDAS 312
CFPI++P + R C+PF+RS+ +C R Q+N LTSF+DAS
Sbjct: 269 CFPIQLP-EEARPAAGTACLPFYRSSAACGTGDQGALFGNLSTANPRQQMNGLTSFLDAS 327
Query: 313 MVYGSEVSLSLRLRNRTNYLGLLAINQRFQDNGRALLPFDNLHDDPCLLTNRS----ARI 368
VYGS +L +LRN T+ GLL ++ R +D+GRA LPF R
Sbjct: 328 TVYGSSPALERQLRNWTSAEGLLRVHARLRDSGRAYLPFVPPRAPAACAPEPGIPGETRG 387
Query: 369 PCFLAGDTRSTETPKLAAMHTLFMREHNRLATELRRLNPRWNGDKLYNEARKIMGAMVQI 428
PCFLAGD R++E P L A+HTL++REHNRLA L+ LN W+ D +Y EARK++GA+ QI
Sbjct: 388 PCFLAGDGRASEVPSLTALHTLWLREHNRLAAALKALNAHWSADAVYQEARKVVGALHQI 447
Query: 429 ITYRDFLPLVLGKARARRTLGHYRGYCSNVDPRVANVF-TLAFRFGHTMLQPFMFRLDSQ 487
IT RD++P +LG ++ +G Y GY S +P V+NVF T AFRFGH + P + RLD+
Sbjct: 448 ITLRDYIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDAS 507
Query: 488 YRASAPNSHVPLSSAFFASWRIVYEGGIDPILRGLMATPAKLNRQDAMLVDELRDRLFRQ 547
++ + L AFF+ W + LRG
Sbjct: 508 FQEHPDLPGLWLHQAFFSPWTL---------LRG-------------------------- 532
Query: 548 VRRIGLDLAALNMQRSRDHGLPGYNAWRRFCGLSQPRNLAQLSRVLKNQDLARKFLNLYG 607
GYN WR FCGL + A LS + ++ +A K L+LY
Sbjct: 533 ----------------------GYNEWREFCGLPRLETPADLSTAIASRSVADKILDLYK 570
Query: 608 TPDNIDIWIGAIAEPLLPGARVGPLLACLFENQFRRARDGDRFWWQKRGVFTKRQRKALS 667
PDNID+W+G +AE LP AR GPL ACL Q + RDGD FWW+ VFT QR+ L
Sbjct: 571 HPDNIDVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSHVFTDAQRRELE 630
Query: 668 RISLSRIICDNTGITTVSRDIFRANIYPRGFVNCSRIPRLNLSAWRGT 715
+ SLSR+ICDNTG+T V D F+ +P F +C I +NL AWR T
Sbjct: 631 KHSLSRVICDNTGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAWRET 678
>gi|126517478 peroxidasin homolog-like [Homo sapiens]
Length = 1463
Score = 450 bits (1157), Expect = e-126
Identities = 272/703 (38%), Positives = 374/703 (53%), Gaps = 36/703 (5%)
Query: 31 VETSVLRDCIAEAKLLVDAAYNWTQKSIKQRLRSGSASPMDLLSYFKQPVAATRTVVRAA 90
VE+S+L +A VD+A N T++ + + S+ + Y + P+ + RA
Sbjct: 610 VESSIL-----DAVQRVDSAINSTRRHLFSQKPHTSSDLLAQFHYPRDPLIVE--MARAG 662
Query: 91 DYMHVALGLLEEKLQPQ-----RSGPFNVTDVLTEPQLRLLSQASGCALRDQAERCSD-- 143
+ L L+ E+++ F D+++ L L++ SGC R CS+
Sbjct: 663 EIFEHTLQLIRERVKQGLTVDLEGKEFRYNDLVSPRSLSLIANLSGCTARRPLPNCSNRC 722
Query: 144 ---KYRTITGRCNNKRRPLLGASNQALARWLPAEYEDGLSLPFGW-TPSRRRNGFLLPLV 199
KYR G CNN ++P GA+ A AR L Y DG+ P G P R LP
Sbjct: 723 FHAKYRAHDGTCNNLQQPTWGAALTAFARLLQPAYRDGIRAPRGLGLPVGSRQP--LPPP 780
Query: 200 RAVSNQIVRFPNERLTSDRGRALMFMQWGQFIDHDLDFSPESPARVAFTAGVDCERTCAQ 259
R V+ R +T D M M WG F++HDLD + + + F+ G C C
Sbjct: 781 RLVATVWARAA--AVTPDHSYTRMLMHWGWFLEHDLDHTVPALSTARFSDGRPCSSVCTN 838
Query: 260 LPPCFPIKIPPNDPRIKNQRDCIPFFRSAPSCPQNKNRV-------RNQINALTSFVDAS 312
PPCFP+ DPR C+ F RS+P+C + R QIN T+++D S
Sbjct: 839 DPPCFPMNTRHADPR-GTHAPCMLFARSSPACASGRPSATVDSVYAREQINQQTAYIDGS 897
Query: 313 MVYGSEVSLSLRLRNRTNYLGLLAINQRFQDNGRALLPFDNLHDDPCLLTNRSARIPCFL 372
VYGS S LR+ + GLL + +G+ LLPF C + + PCFL
Sbjct: 898 NVYGSSERESQALRDPSVPRGLLKTGFPWPPSGKPLLPFSTGPPTECARQEQES--PCFL 955
Query: 373 AGDTRSTETPKLAAMHTLFMREHNRLATELRRLNPRWNGDKLYNEARKIMGAMVQIITYR 432
AGD R+ E LAAMHTL+ REHNR+ATEL LNP W G+ +Y EARKI+GA +Q ITY
Sbjct: 956 AGDHRANEHLALAAMHTLWFREHNRVATELSALNPHWEGNTVYQEARKIVGAELQHITYS 1015
Query: 433 DFLPLVLGKARARRTLGHYRGYCSNVDPRVANVF-TLAFRFGHTMLQPFMFRLDSQYRAS 491
+LP VLG R G YRGY NV+ + N F T AFRFGHT++ P ++RL++
Sbjct: 1016 HWLPKVLGDPGTRMLRG-YRGYNPNVNAGIINSFATAAFRFGHTLINPILYRLNATL-GE 1073
Query: 492 APNSHVPLSSAFFASWRIVYEGGIDPILRGLMATPAKLNRQDAMLVDELRDRLFRQVRRI 551
H+P A F+ RI+ EGGIDP+LRGL AK +L EL RLF
Sbjct: 1074 ISEGHLPFHKALFSPSRIIKEGGIDPVLRGLFGVAAKWRAPSYLLSPELTQRLFSAAYSA 1133
Query: 552 GLDLAALNMQRSRDHGLPGYNAWRRFCGLSQPRNLAQLSRVLKNQDLARKFLNLYGTPDN 611
+D AA +QR RDHG+P Y +R FC L+ +N L +K+ ++ +K LYG+P +
Sbjct: 1134 AVDSAATIIQRGRDHGIPPYVDFRVFCNLTSVKNFEDLQNEIKDSEIRQKLRKLYGSPGD 1193
Query: 612 IDIWIGAIAEPLLPGARVGPLLACLFENQFRRARDGDRFWWQKRGVFTKRQRKALSRISL 671
ID+W + E L+PG RVGP L CLF QF+R RDGDRFW++ GVFT Q L + SL
Sbjct: 1194 IDLWPALMVEDLIPGTRVGPTLMCLFVTQFQRLRDGDRFWYENPGVFTPAQLTQLKQASL 1253
Query: 672 SRIICDN-TGITTVSRDIFRANIYPRGFVNCSRIPRLNLSAWR 713
SR++CDN I V D+F YP+ ++NCS IP+++L W+
Sbjct: 1254 SRVLCDNGDSIQQVQADVFVKAEYPQDYLNCSEIPKVDLRVWQ 1296
>gi|28558990 thyroid peroxidase isoform e [Homo sapiens]
Length = 760
Score = 292 bits (747), Expect = 8e-79
Identities = 141/291 (48%), Positives = 189/291 (64%), Gaps = 1/291 (0%)
Query: 426 VQIITYRDFLPLVLGKARARRTLGHYRGYCSNVDPRVANVF-TLAFRFGHTMLQPFMFRL 484
+QIIT RD++P +LG ++ +G Y GY S +P V+NVF T AFRFGH + P + RL
Sbjct: 272 IQIITLRDYIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRL 331
Query: 485 DSQYRASAPNSHVPLSSAFFASWRIVYEGGIDPILRGLMATPAKLNRQDAMLVDELRDRL 544
D+ ++ + L AFF+ W ++ GG+DP++RGL+A PAKL QD ++ +EL +RL
Sbjct: 332 DASFQEHPDLPGLWLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERL 391
Query: 545 FRQVRRIGLDLAALNMQRSRDHGLPGYNAWRRFCGLSQPRNLAQLSRVLKNQDLARKFLN 604
F LDLA++N+QR RDHGLPGYN WR FCGL + A LS + ++ +A K L+
Sbjct: 392 FVLSNSSTLDLASINLQRGRDHGLPGYNEWREFCGLPRLETPADLSTAIASRSVADKILD 451
Query: 605 LYGTPDNIDIWIGAIAEPLLPGARVGPLLACLFENQFRRARDGDRFWWQKRGVFTKRQRK 664
LY PDNID+W+G +AE LP AR GPL ACL Q + RDGD FWW+ VFT QR+
Sbjct: 452 LYKHPDNIDVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSHVFTDAQRR 511
Query: 665 ALSRISLSRIICDNTGITTVSRDIFRANIYPRGFVNCSRIPRLNLSAWRGT 715
L + SLSR+ICDNTG+T V D F+ +P F +C I +NL AWR T
Sbjct: 512 ELEKHSLSRVICDNTGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAWRET 562
Score = 187 bits (475), Expect = 3e-47
Identities = 101/246 (41%), Positives = 142/246 (57%), Gaps = 9/246 (3%)
Query: 29 GAVETSVLRDCIAEAKLLVDAA-YNWTQKSIKQRLRSGSASPMDLLSYFKQPVAATRTVV 87
G E S + + E+K LVD A Y Q+++K+R G SP LLS+ K P + +
Sbjct: 32 GKPEESRVSSVLEESKRLVDTAMYATMQRNLKKR---GILSPAQLLSFSKLPEPTSGVIA 88
Query: 88 RAADYMHVALGLLEEKLQPQRSGPFNVTDVLTEPQLRLLSQASGCALRDQAERC-----S 142
RAA+ M ++ ++ K+ + + TD L+E L +++ SGC +C +
Sbjct: 89 RAAEIMETSIQAMKRKVNLKTQQSQHPTDALSEDLLSIIANMSGCLPYMLPPKCPNTCLA 148
Query: 143 DKYRTITGRCNNKRRPLLGASNQALARWLPAEYEDGLSLPFGWTPSRRRNGFLLPLVRAV 202
+KYR ITG CNN+ P GASN ALARWLP YEDG S P GW P NGF LP VR V
Sbjct: 149 NKYRPITGACNNRDHPRWGASNTALARWLPPVYEDGFSQPRGWNPGFLYNGFPLPPVREV 208
Query: 203 SNQIVRFPNERLTSDRGRALMFMQWGQFIDHDLDFSPESPARVAFTAGVDCERTCAQLPP 262
+ +++ NE +T D + + M WGQ+IDHD+ F+P+S ++ AF G DC+ TC P
Sbjct: 209 TRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHDIAFTPQSTSKAAFGGGADCQMTCENQNP 268
Query: 263 CFPIKI 268
CFPI+I
Sbjct: 269 CFPIQI 274
>gi|20149640 dual oxidase 1 precursor [Homo sapiens]
Length = 1551
Score = 139 bits (351), Expect = 7e-33
Identities = 154/548 (28%), Positives = 247/548 (45%), Gaps = 62/548 (11%)
Query: 150 GRCNNKRRPLLGASNQALARWLPAEYEDGLSLPFGWTPSRRRNGFLLPLVRAVSNQIVRF 209
G NN G+ L R +PA Y DG+ P G LP R +SN I R
Sbjct: 34 GWYNNLMEHRWGSKGSRLQRLVPASYADGVYQPLGEPH--------LPNPRDLSNTISRG 85
Query: 210 PNERLTSDRGRALMFMQWGQFIDHDLDFSPESPARVAFTAGVDCERTCAQLPPCFPIKIP 269
P L S R R ++ + +G + DL S E+P A I+IP
Sbjct: 86 P-AGLASLRNRTVLGVFFGYHVLSDL-VSVETPGCPA---------------EFLNIRIP 128
Query: 270 PNDPRIK-NQRD--CIPFFRSA--PSCPQNKNRVRNQINALTSFVDASMVYGSEVSLSLR 324
P DP +QR +PF RS P ++ + R+ N +T ++D S +YGS S S
Sbjct: 129 PGDPMFDPDQRGDVVLPFQRSRWDPETGRSPSNPRDPANQVTGWLDGSAIYGSSHSWSDA 188
Query: 325 LRNRTNYLGLLAINQRF-QDNGRALLPFDNLHDDPCLLTNRSARIPCFLAGDTRSTETPK 383
LR+ + + F +D+ LL + DP N + F G R P
Sbjct: 189 LRSFSRGQLASGPDPAFPRDSQNPLLMW--AAPDPATGQNGPRGLYAF--GAERGNREPF 244
Query: 384 LAAMHTLFMREHNRLATELRRLNPRWNGDKLYNEARKIMGAMVQIITYRDFLPLVLGKAR 443
L A+ L+ R HN A L R +P W ++L+ ARK + A Q I ++LP L
Sbjct: 245 LQALGLLWFRYHNLWAQRLARQHPDWEDEELFQHARKRVIATYQNIAVYEWLPSFL---- 300
Query: 444 ARRTLGHYRGYCSNVDPRVANVFTLAF-RFGHTMLQPFMFRLDSQ-------YRASAPNS 495
++TL Y GY +DP +++ F A +F TM+ P ++ ++ R S+ +
Sbjct: 301 -QKTLPEYTGYRPFLDPSISSEFVAASEQFLSTMVPPGVYMRNASCHFQGVINRNSSVSR 359
Query: 496 HVPLSSAFFASWRIVYEGG--IDPILRGLMATPAKLNRQDAMLVDELRDRLFRQVRRIGL 553
+ + +++++ + +D +L G+ + A+ R+D +LV+++RD ++
Sbjct: 360 ALRVCNSYWSREHPSLQSAEDVDALLLGMASQIAE--REDHVLVEDVRDFWPGPLKFSRT 417
Query: 554 DLAALNMQRSRDHGLPGYNAWRRFCGLSQPRNLAQLSRVL--KNQDLARKFLNLYGTPDN 611
D A +QR RD GLP Y R GLS ++ L N + LY N
Sbjct: 418 DHLASCLQRGRDLGLPSYTKARAALGLSPITRWQDINPALSRSNDTVLEATAALY----N 473
Query: 612 IDI-WIGAIAEPLLPGAR-VGPLLACLFENQFRRARDGDRFWWQ--KRGVFTKRQRKALS 667
D+ W+ + LL R GPL + + QF R RDGDR+W++ + G+F+K++ + +
Sbjct: 474 QDLSWLELLPGGLLESHRDPGPLFSTIVLEQFVRLRDGDRYWFENTRNGLFSKKEIEEIR 533
Query: 668 RISLSRII 675
+L ++
Sbjct: 534 NTTLQDVL 541
>gi|28872751 dual oxidase 1 precursor [Homo sapiens]
Length = 1551
Score = 139 bits (351), Expect = 7e-33
Identities = 154/548 (28%), Positives = 247/548 (45%), Gaps = 62/548 (11%)
Query: 150 GRCNNKRRPLLGASNQALARWLPAEYEDGLSLPFGWTPSRRRNGFLLPLVRAVSNQIVRF 209
G NN G+ L R +PA Y DG+ P G LP R +SN I R
Sbjct: 34 GWYNNLMEHRWGSKGSRLQRLVPASYADGVYQPLGEPH--------LPNPRDLSNTISRG 85
Query: 210 PNERLTSDRGRALMFMQWGQFIDHDLDFSPESPARVAFTAGVDCERTCAQLPPCFPIKIP 269
P L S R R ++ + +G + DL S E+P A I+IP
Sbjct: 86 P-AGLASLRNRTVLGVFFGYHVLSDL-VSVETPGCPA---------------EFLNIRIP 128
Query: 270 PNDPRIK-NQRD--CIPFFRSA--PSCPQNKNRVRNQINALTSFVDASMVYGSEVSLSLR 324
P DP +QR +PF RS P ++ + R+ N +T ++D S +YGS S S
Sbjct: 129 PGDPMFDPDQRGDVVLPFQRSRWDPETGRSPSNPRDPANQVTGWLDGSAIYGSSHSWSDA 188
Query: 325 LRNRTNYLGLLAINQRF-QDNGRALLPFDNLHDDPCLLTNRSARIPCFLAGDTRSTETPK 383
LR+ + + F +D+ LL + DP N + F G R P
Sbjct: 189 LRSFSRGQLASGPDPAFPRDSQNPLLMW--AAPDPATGQNGPRGLYAF--GAERGNREPF 244
Query: 384 LAAMHTLFMREHNRLATELRRLNPRWNGDKLYNEARKIMGAMVQIITYRDFLPLVLGKAR 443
L A+ L+ R HN A L R +P W ++L+ ARK + A Q I ++LP L
Sbjct: 245 LQALGLLWFRYHNLWAQRLARQHPDWEDEELFQHARKRVIATYQNIAVYEWLPSFL---- 300
Query: 444 ARRTLGHYRGYCSNVDPRVANVFTLAF-RFGHTMLQPFMFRLDSQ-------YRASAPNS 495
++TL Y GY +DP +++ F A +F TM+ P ++ ++ R S+ +
Sbjct: 301 -QKTLPEYTGYRPFLDPSISSEFVAASEQFLSTMVPPGVYMRNASCHFQGVINRNSSVSR 359
Query: 496 HVPLSSAFFASWRIVYEGG--IDPILRGLMATPAKLNRQDAMLVDELRDRLFRQVRRIGL 553
+ + +++++ + +D +L G+ + A+ R+D +LV+++RD ++
Sbjct: 360 ALRVCNSYWSREHPSLQSAEDVDALLLGMASQIAE--REDHVLVEDVRDFWPGPLKFSRT 417
Query: 554 DLAALNMQRSRDHGLPGYNAWRRFCGLSQPRNLAQLSRVL--KNQDLARKFLNLYGTPDN 611
D A +QR RD GLP Y R GLS ++ L N + LY N
Sbjct: 418 DHLASCLQRGRDLGLPSYTKARAALGLSPITRWQDINPALSRSNDTVLEATAALY----N 473
Query: 612 IDI-WIGAIAEPLLPGAR-VGPLLACLFENQFRRARDGDRFWWQ--KRGVFTKRQRKALS 667
D+ W+ + LL R GPL + + QF R RDGDR+W++ + G+F+K++ + +
Sbjct: 474 QDLSWLELLPGGLLESHRDPGPLFSTIVLEQFVRLRDGDRYWFENTRNGLFSKKEIEEIR 533
Query: 668 RISLSRII 675
+L ++
Sbjct: 534 NTTLQDVL 541
>gi|132566532 dual oxidase 2 precursor [Homo sapiens]
Length = 1548
Score = 124 bits (311), Expect = 3e-28
Identities = 149/546 (27%), Positives = 240/546 (43%), Gaps = 61/546 (11%)
Query: 150 GRCNNKRRPLLGASNQALARWLPAEYEDGL--SLPFGWTPSRRRNGFLLPLVRAVSNQIV 207
G NN R GA L R +PA Y DG+ +L P+ RR L A + I
Sbjct: 40 GWFNNLRHHERGAVGCRLQRRVPANYADGVYQALEEPQLPNPRR------LSNAATRGIA 93
Query: 208 RFPNERLTSDRGRALMFMQWGQFIDHDLDFSPESPARVAFTAGVDCERTCAQLPPCFPIK 267
P S R ++ + +G + D+ S E+P A I+
Sbjct: 94 GLP-----SLHNRTVLGVFFGYHVLSDV-VSVETPGCPA---------------EFLNIR 132
Query: 268 IPPNDPRIK-NQRD--CIPFFRSA--PSCPQNKNRVRNQINALTSFVDASMVYGSEVSLS 322
IPP DP +QR +PF RS P ++ + R+ N +T ++D S +YGS S S
Sbjct: 133 IPPGDPVFDPDQRGDVVLPFQRSRWDPETGRSPSNPRDLANQVTGWLDGSAIYGSSHSWS 192
Query: 323 LRLRNRTNYLGLLAINQRF-QDNGRALLPFDNLHDDPCLLTNRSARIPCFLAGDTRSTET 381
LR+ + + F +D+ LL + DP N + F G R
Sbjct: 193 DALRSFSGGQLASGPDPAFPRDSQNPLLMW--AAPDPATGQNGPRGLYAF--GAERGNRE 248
Query: 382 PKLAAMHTLFMREHNRLATELRRLNPRWNGDKLYNEARKIMGAMVQIITYRDFLPLVLGK 441
P L A+ L+ R HN A L R +P W ++L+ ARK + A Q I ++LP L
Sbjct: 249 PFLQALGLLWFRYHNLWAQRLARQHPDWEDEELFQHARKRVIATYQNIAVYEWLPSFL-- 306
Query: 442 ARARRTLGHYRGYCSNVDPRVANVFTLAF-RFGHTMLQPFMF-RLDSQYRASAPNSHVPL 499
++TL Y GY +DP ++ F +A +F TM+ P ++ R S + N
Sbjct: 307 ---QKTLPEYTGYRPFLDPSISPEFVVASEQFFSTMVPPGVYMRNASCHFRKVLNKGFQS 363
Query: 500 SSAFFAS---W-----RIVYEGGIDPILRGLMATPAKLNRQDAMLVDELRDRLFRQVRRI 551
S A W + ++ +L G+ + ++L +D ++V++LRD +
Sbjct: 364 SQALRVCNNYWIRENPNLNSTQEVNELLLGMASQISEL--EDNIVVEDLRDYWPGPGKFS 421
Query: 552 GLDLAALNMQRSRDHGLPGYNAWRRFCGLSQPRNLAQLSRVLKNQDLARKFLNLYGTPDN 611
D A ++QR RD GLP Y+ GL PRN + L+ + Q L
Sbjct: 422 RTDYVASSIQRGRDMGLPSYSQALLAFGLDIPRNWSDLNPNVDPQVLEATAALYNQDLSQ 481
Query: 612 IDIWIGAIAEPLLPGARVGPLLACLFENQFRRARDGDRFWWQ--KRGVFTKRQRKALSRI 669
+++ +G + E GPL + + +QF R RDGDR+W++ + G+F+K++ + +
Sbjct: 482 LELLLGGLLE---SHGDPGPLFSAIVLDQFVRLRDGDRYWFENTRNGLFSKKEIEDIRNT 538
Query: 670 SLSRII 675
+L ++
Sbjct: 539 TLRDVL 544
>gi|18104967 prostaglandin-endoperoxide synthase 1 isoform 1
precursor [Homo sapiens]
Length = 599
Score = 38.5 bits (88), Expect = 0.022
Identities = 53/257 (20%), Positives = 106/257 (41%), Gaps = 41/257 (15%)
Query: 382 PKLAAMHTLFMREHNRLATELRRLNPRWNGDKLYNEARKIM-GAMVQIITYR-------D 433
P L TL++REHNR+ L+ +P W ++L+ R I+ G ++I+
Sbjct: 295 PGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGY 354
Query: 434 FLPLVLGKARARRTLGHYRGYCSNVDPRVANVFTLAFRFGHTMLQPFMFRLDSQYRASAP 493
FL L YR R+A F + + L P F++ SQ +
Sbjct: 355 FLQLKFDPELLFGVQFQYRN-------RIAMEFNHLYHW--HPLMPDSFKVGSQEYS--- 402
Query: 494 NSHVPLSSAFFASWRIVYEGGIDPILRGLMATPAKLNRQDAMLVDELRDRLFRQVRRIGL 553
F + ++ + G++ ++ +RQ A + R+ + + + +
Sbjct: 403 ------YEQFLFNTSMLVDYGVEALVDA-------FSRQIAGRIGGGRN-MDHHILHVAV 448
Query: 554 DLAALNMQRSRDHGLPGYNAWRRFCGLSQPRNLAQLSRVLKNQDLARKFLNLYGTPDNID 613
D+ ++ SR+ L +N +R+ G+ + +L + +++A + LYG D ++
Sbjct: 449 DV----IRESREMRLQPFNEYRKRFGMKPYTSFQEL---VGEKEMAAELEELYGDIDALE 501
Query: 614 IWIGAIAEPLLPGARVG 630
+ G + E P + G
Sbjct: 502 FYPGLLLEKCHPNSIFG 518
>gi|4506265 prostaglandin-endoperoxide synthase 2 precursor [Homo
sapiens]
Length = 604
Score = 37.4 bits (85), Expect = 0.049
Identities = 16/49 (32%), Positives = 31/49 (63%), Gaps = 1/49 (2%)
Query: 382 PKLAAMHTLFMREHNRLATELRRLNPRWNGDKLYNEARKIM-GAMVQII 429
P L T+++REHNR+ L++ +P W ++L+ +R I+ G ++I+
Sbjct: 282 PGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIV 330
>gi|18104969 prostaglandin-endoperoxide synthase 1 isoform 2
precursor [Homo sapiens]
Length = 562
Score = 36.2 bits (82), Expect = 0.11
Identities = 17/49 (34%), Positives = 29/49 (59%), Gaps = 1/49 (2%)
Query: 382 PKLAAMHTLFMREHNRLATELRRLNPRWNGDKLYNEARKIM-GAMVQII 429
P L TL++REHNR+ L+ +P W ++L+ R I+ G ++I+
Sbjct: 295 PGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIV 343
>gi|96975023 ankyrin repeat and death domain containing 1A [Homo
sapiens]
Length = 522
Score = 32.3 bits (72), Expect = 1.6
Identities = 44/185 (23%), Positives = 68/185 (36%), Gaps = 17/185 (9%)
Query: 423 GAMVQIITYRDFLPL----VLGKARARRTLGHYRGYCSNVDPRVANVFTLAFRFGHTMLQ 478
G+ V +T ++ L + G R L H G + VD + A+ LA R L
Sbjct: 248 GSTVNALTQKNLSCLHYAALSGSEDVSRVLIHAGGCANVVDHQGASPLHLAVRHNFPALV 307
Query: 479 PFMFRLDSQYRASAPNSHVPLSSAFFASWRIVYE----GGIDPILR---GLMATPAKLNR 531
+ DS A PL A +W+ + + G+D LR G A +
Sbjct: 308 RLLINSDSDVNAVDNRQQTPLHLAAEHAWQDIADMLLIAGVDLNLRDKQGKTALAVAVRS 367
Query: 532 QDAMLVDEL--RDRLFRQVRRIGLDLAALNMQRSRDHGLPGYN----AWRRFCGLSQPRN 585
LVD + DR +R + D + ++ +DH WR QPR
Sbjct: 368 NHVSLVDMIIKADRFYRWEKDHPSDPSGKSLSFKQDHRQETQQLRSVLWRLASRYLQPRE 427
Query: 586 LAQLS 590
+L+
Sbjct: 428 WKKLA 432
>gi|4557665 insulin-like growth factor 1 receptor precursor [Homo
sapiens]
Length = 1367
Score = 31.2 bits (69), Expect = 3.5
Identities = 19/52 (36%), Positives = 24/52 (46%), Gaps = 1/52 (1%)
Query: 145 YRTITGRCNNKRRPL-LGASNQALARWLPAEYEDGLSLPFGWTPSRRRNGFL 195
YR CN++ L ASN AR +PAE D + P W P + FL
Sbjct: 799 YRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTWEPRPENSIFL 850
>gi|239755538 PREDICTED: hypothetical protein [Homo sapiens]
Length = 114
Score = 30.8 bits (68), Expect = 4.6
Identities = 22/70 (31%), Positives = 34/70 (48%), Gaps = 4/70 (5%)
Query: 526 PAKLNRQDAMLVDELRDRLF---RQVRRIGLDLAALNMQRSRDHGLPGYNAWRRFCGLSQ 582
PA + A LR RLF R+ +G + N+ R +D ++AW R CG+S
Sbjct: 21 PAPRSTPAATQSSSLRMRLFQGHRKEENLGQMVREGNL-RVQDTSAHPHSAWHRSCGISP 79
Query: 583 PRNLAQLSRV 592
R ++ L R+
Sbjct: 80 QRTVSTLERL 89
>gi|239749994 PREDICTED: hypothetical protein XP_002347233 [Homo
sapiens]
Length = 114
Score = 30.8 bits (68), Expect = 4.6
Identities = 22/70 (31%), Positives = 34/70 (48%), Gaps = 4/70 (5%)
Query: 526 PAKLNRQDAMLVDELRDRLF---RQVRRIGLDLAALNMQRSRDHGLPGYNAWRRFCGLSQ 582
PA + A LR RLF R+ +G + N+ R +D ++AW R CG+S
Sbjct: 21 PAPRSTPAATQSSSLRMRLFQGHRKEENLGQMVREGNL-RVQDTSAHPHSAWHRSCGISP 79
Query: 583 PRNLAQLSRV 592
R ++ L R+
Sbjct: 80 QRTVSTLERL 89
>gi|239744305 PREDICTED: hypothetical protein XP_002343094 [Homo
sapiens]
Length = 114
Score = 30.8 bits (68), Expect = 4.6
Identities = 22/70 (31%), Positives = 34/70 (48%), Gaps = 4/70 (5%)
Query: 526 PAKLNRQDAMLVDELRDRLF---RQVRRIGLDLAALNMQRSRDHGLPGYNAWRRFCGLSQ 582
PA + A LR RLF R+ +G + N+ R +D ++AW R CG+S
Sbjct: 21 PAPRSTPAATQSSSLRMRLFQGHRKEENLGQMVREGNL-RVQDTSAHPHSAWHRSCGISP 79
Query: 583 PRNLAQLSRV 592
R ++ L R+
Sbjct: 80 QRTVSTLERL 89
>gi|148612875 RUN and TBC1 domain containing 2 isoform 4 [Homo
sapiens]
Length = 1032
Score = 30.4 bits (67), Expect = 6.0
Identities = 36/169 (21%), Positives = 68/169 (40%), Gaps = 19/169 (11%)
Query: 89 AADYM-HVALGLLEEKLQPQRSGPFNVTDV--LTEPQLRLLSQASGCALRDQAERCSDKY 145
A DY+ + ++ + PQ +V+++ L +P R S S C+ A+ S
Sbjct: 414 ATDYVFRIIYPGMQSEFVPQDLMDVSVSNLPSLWQPSPRK-SSCSSCSQSGSADGSS--- 469
Query: 146 RTITGRCNNKRRPLLGASNQALARWLPAEYEDGLSLPFGWTPSRRRNGFLLPLVRAVSNQ 205
T CN++R PL + + L + +GW R + + A+ N
Sbjct: 470 ---TNGCNHERAPLKLLCDNMKYQILSRAF-------YGWLAYCRHLSTVRTHLSALVNH 519
Query: 206 IVRFPNERLTSDRGRALMFMQWGQFIDHDLDFSPESPARVAFTAGVDCE 254
++ P+ L D G+ L W Q++ + + R+ + G+ E
Sbjct: 520 MIVSPD--LPCDAGQGLTARIWEQYLHDSTSYEEQELLRLIYYGGIQPE 566
>gi|148612840 RUN and TBC1 domain containing 2 isoform 3 [Homo
sapiens]
Length = 1093
Score = 30.4 bits (67), Expect = 6.0
Identities = 36/169 (21%), Positives = 68/169 (40%), Gaps = 19/169 (11%)
Query: 89 AADYM-HVALGLLEEKLQPQRSGPFNVTDV--LTEPQLRLLSQASGCALRDQAERCSDKY 145
A DY+ + ++ + PQ +V+++ L +P R S S C+ A+ S
Sbjct: 414 ATDYVFRIIYPGMQSEFVPQDLMDVSVSNLPSLWQPSPRK-SSCSSCSQSGSADGSS--- 469
Query: 146 RTITGRCNNKRRPLLGASNQALARWLPAEYEDGLSLPFGWTPSRRRNGFLLPLVRAVSNQ 205
T CN++R PL + + L + +GW R + + A+ N
Sbjct: 470 ---TNGCNHERAPLKLLCDNMKYQILSRAF-------YGWLAYCRHLSTVRTHLSALVNH 519
Query: 206 IVRFPNERLTSDRGRALMFMQWGQFIDHDLDFSPESPARVAFTAGVDCE 254
++ P+ L D G+ L W Q++ + + R+ + G+ E
Sbjct: 520 MIVSPD--LPCDAGQGLTARIWEQYLHDSTSYEEQELLRLIYYGGIQPE 566
>gi|90577164 RUN and TBC1 domain containing 2 isoform 2 [Homo
sapiens]
Length = 1087
Score = 30.0 bits (66), Expect = 7.8
Identities = 27/128 (21%), Positives = 49/128 (38%), Gaps = 15/128 (11%)
Query: 127 SQASGCALRDQAERCSDKYRTITGRCNNKRRPLLGASNQALARWLPAEYEDGLSLPFGWT 186
S S C+ A+ S T CN++R PL + + L + +GW
Sbjct: 509 SSCSSCSQSGSADGSS------TNGCNHERAPLKLLCDNMKYQILSRAF-------YGWL 555
Query: 187 PSRRRNGFLLPLVRAVSNQIVRFPNERLTSDRGRALMFMQWGQFIDHDLDFSPESPARVA 246
R + + A+ N ++ P+ L D G+ L W Q++ + + R+
Sbjct: 556 AYCRHLSTVRTHLSALVNHMIVSPD--LPCDAGQGLTARIWEQYLHDSTSYEEQELLRLI 613
Query: 247 FTAGVDCE 254
+ G+ E
Sbjct: 614 YYGGIQPE 621
>gi|90577167 RUN and TBC1 domain containing 2 isoform 1 [Homo
sapiens]
Length = 1148
Score = 30.0 bits (66), Expect = 7.8
Identities = 27/128 (21%), Positives = 49/128 (38%), Gaps = 15/128 (11%)
Query: 127 SQASGCALRDQAERCSDKYRTITGRCNNKRRPLLGASNQALARWLPAEYEDGLSLPFGWT 186
S S C+ A+ S T CN++R PL + + L + +GW
Sbjct: 509 SSCSSCSQSGSADGSS------TNGCNHERAPLKLLCDNMKYQILSRAF-------YGWL 555
Query: 187 PSRRRNGFLLPLVRAVSNQIVRFPNERLTSDRGRALMFMQWGQFIDHDLDFSPESPARVA 246
R + + A+ N ++ P+ L D G+ L W Q++ + + R+
Sbjct: 556 AYCRHLSTVRTHLSALVNHMIVSPD--LPCDAGQGLTARIWEQYLHDSTSYEEQELLRLI 613
Query: 247 FTAGVDCE 254
+ G+ E
Sbjct: 614 YYGGIQPE 621
>gi|4506763 S100 calcium binding protein A3 [Homo sapiens]
Length = 101
Score = 30.0 bits (66), Expect = 7.8
Identities = 15/46 (32%), Positives = 23/46 (50%), Gaps = 7/46 (15%)
Query: 132 CALRDQAERCSDKYRTITGRCNNKRRPLLGASNQALARWLPAEYED 177
C ++ A RC DKY+ C + + LL + LA W P E+ +
Sbjct: 14 CTFQEYAGRCGDKYKL----CQAELKELL---QKELATWTPTEFRE 52
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.138 0.429
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,606,766
Number of Sequences: 37866
Number of extensions: 1146446
Number of successful extensions: 3033
Number of sequences better than 10.0: 26
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 2953
Number of HSP's gapped (non-prelim): 34
length of query: 715
length of database: 18,247,518
effective HSP length: 109
effective length of query: 606
effective length of database: 14,120,124
effective search space: 8556795144
effective search space used: 8556795144
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.