BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|4503559 epithelial membrane protein 1 [Homo sapiens] (157 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|4503559 epithelial membrane protein 1 [Homo sapiens] 319 7e-88 gi|4505907 peripheral myelin protein 22 [Homo sapiens] 127 3e-30 gi|24430165 peripheral myelin protein 22 [Homo sapiens] 127 3e-30 gi|24430163 peripheral myelin protein 22 [Homo sapiens] 127 3e-30 gi|4503561 epithelial membrane protein 2 [Homo sapiens] 121 3e-28 gi|4503563 epithelial membrane protein 3 [Homo sapiens] 94 6e-20 gi|239747698 PREDICTED: similar to hCG1784039 [Homo sapiens] 69 2e-12 gi|239916002 lens intrinsic membrane protein 2, 19kDa isoform 2 ... 56 1e-08 gi|50345279 claudin 18 isoform 2 [Homo sapiens] 49 1e-06 gi|7705961 claudin 18 isoform 1 [Homo sapiens] 47 9e-06 gi|21361300 lens intrinsic membrane protein 2, 19kDa isoform 1 [... 44 7e-05 gi|22748765 claudin domain containing 2 [Homo sapiens] 43 1e-04 gi|169163665 PREDICTED: similar to hCG1784039 [Homo sapiens] 40 0.001 gi|169163222 PREDICTED: hypothetical protein LOC391359 [Homo sap... 40 0.001 gi|5921465 claudin 10 isoform b [Homo sapiens] 36 0.015 gi|122937323 transmembrane protein 202 [Homo sapiens] 36 0.015 gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo sa... 35 0.020 gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo sa... 35 0.020 gi|24586686 voltage-dependent calcium channel gamma-8 subunit [H... 35 0.026 gi|183979973 claudin 19 isoform a [Homo sapiens] 33 0.076 gi|124107616 claudin 23 [Homo sapiens] 33 0.076 gi|10938016 claudin 11 [Homo sapiens] 33 0.076 gi|183979975 claudin 19 isoform b [Homo sapiens] 33 0.076 gi|5174405 voltage-dependent calcium channel gamma-2 subunit [Ho... 33 0.100 gi|5729756 voltage-dependent calcium channel gamma-3 subunit [Ho... 33 0.100 gi|153792768 claudin 6 [Homo sapiens] 32 0.22 gi|33598916 claudin 10 isoform a [Homo sapiens] 32 0.22 gi|231569235 claudin 10 isoform a_i1 [Homo sapiens] 32 0.29 gi|239756473 PREDICTED: transmembrane protein 114 [Homo sapiens] 31 0.38 gi|239752599 PREDICTED: transmembrane protein 114, partial [Homo... 31 0.38 >gi|4503559 epithelial membrane protein 1 [Homo sapiens] Length = 157 Score = 319 bits (817), Expect = 7e-88 Identities = 157/157 (100%), Positives = 157/157 (100%) Query: 1 MLVLLAGIFVVHIATVIMLFVSTIANVWLVSNTVDASVGLWKNCTNISCSDSLSYASEDA 60 MLVLLAGIFVVHIATVIMLFVSTIANVWLVSNTVDASVGLWKNCTNISCSDSLSYASEDA Sbjct: 1 MLVLLAGIFVVHIATVIMLFVSTIANVWLVSNTVDASVGLWKNCTNISCSDSLSYASEDA 60 Query: 61 LKTVQAFMILSIIFCVIALLVFVFQLFTMEKGNRFFLSGATTLVCWLCILVGVSIYTSHY 120 LKTVQAFMILSIIFCVIALLVFVFQLFTMEKGNRFFLSGATTLVCWLCILVGVSIYTSHY Sbjct: 61 LKTVQAFMILSIIFCVIALLVFVFQLFTMEKGNRFFLSGATTLVCWLCILVGVSIYTSHY 120 Query: 121 ANRDGTQYHHGYSYILGWICFCFSFIIGVLYLVLRKK 157 ANRDGTQYHHGYSYILGWICFCFSFIIGVLYLVLRKK Sbjct: 121 ANRDGTQYHHGYSYILGWICFCFSFIIGVLYLVLRKK 157 >gi|4505907 peripheral myelin protein 22 [Homo sapiens] Length = 160 Score = 127 bits (320), Expect = 3e-30 Identities = 64/161 (39%), Positives = 104/161 (64%), Gaps = 6/161 (3%) Query: 1 MLVLLAGIFVVHIATVIMLFVSTIANVWLVSNTVDASVGLWKNCTNISCSD---SLSYAS 57 ML+LL I V+H+A +++LFVSTI + W+V N + LW+NC+ S + S + Sbjct: 1 MLLLLLSIIVLHVAVLVLLFVSTIVSQWIVGN--GHATDLWQNCSTSSSGNVHHCFSSSP 58 Query: 58 EDALKTVQAFMILSIIFCVIALLVFVFQLFTMEKGNRFFLSGATTLVCWLCILVGVSIYT 117 + L++VQA MILSIIF +++L +F QLFT+ KG RF+++G ++ LC++ +IYT Sbjct: 59 NEWLQSVQATMILSIIFSILSLFLFFCQLFTLTKGGRFYITGIFQILAGLCVMSAAAIYT 118 Query: 118 -SHYANRDGTQYHHGYSYILGWICFCFSFIIGVLYLVLRKK 157 H + Y +G++YIL W+ F + + GV+Y++LRK+ Sbjct: 119 VRHPEWHLNSDYSYGFAYILAWVAFPLALLSGVIYVILRKR 159 >gi|24430165 peripheral myelin protein 22 [Homo sapiens] Length = 160 Score = 127 bits (320), Expect = 3e-30 Identities = 64/161 (39%), Positives = 104/161 (64%), Gaps = 6/161 (3%) Query: 1 MLVLLAGIFVVHIATVIMLFVSTIANVWLVSNTVDASVGLWKNCTNISCSD---SLSYAS 57 ML+LL I V+H+A +++LFVSTI + W+V N + LW+NC+ S + S + Sbjct: 1 MLLLLLSIIVLHVAVLVLLFVSTIVSQWIVGN--GHATDLWQNCSTSSSGNVHHCFSSSP 58 Query: 58 EDALKTVQAFMILSIIFCVIALLVFVFQLFTMEKGNRFFLSGATTLVCWLCILVGVSIYT 117 + L++VQA MILSIIF +++L +F QLFT+ KG RF+++G ++ LC++ +IYT Sbjct: 59 NEWLQSVQATMILSIIFSILSLFLFFCQLFTLTKGGRFYITGIFQILAGLCVMSAAAIYT 118 Query: 118 -SHYANRDGTQYHHGYSYILGWICFCFSFIIGVLYLVLRKK 157 H + Y +G++YIL W+ F + + GV+Y++LRK+ Sbjct: 119 VRHPEWHLNSDYSYGFAYILAWVAFPLALLSGVIYVILRKR 159 >gi|24430163 peripheral myelin protein 22 [Homo sapiens] Length = 160 Score = 127 bits (320), Expect = 3e-30 Identities = 64/161 (39%), Positives = 104/161 (64%), Gaps = 6/161 (3%) Query: 1 MLVLLAGIFVVHIATVIMLFVSTIANVWLVSNTVDASVGLWKNCTNISCSD---SLSYAS 57 ML+LL I V+H+A +++LFVSTI + W+V N + LW+NC+ S + S + Sbjct: 1 MLLLLLSIIVLHVAVLVLLFVSTIVSQWIVGN--GHATDLWQNCSTSSSGNVHHCFSSSP 58 Query: 58 EDALKTVQAFMILSIIFCVIALLVFVFQLFTMEKGNRFFLSGATTLVCWLCILVGVSIYT 117 + L++VQA MILSIIF +++L +F QLFT+ KG RF+++G ++ LC++ +IYT Sbjct: 59 NEWLQSVQATMILSIIFSILSLFLFFCQLFTLTKGGRFYITGIFQILAGLCVMSAAAIYT 118 Query: 118 -SHYANRDGTQYHHGYSYILGWICFCFSFIIGVLYLVLRKK 157 H + Y +G++YIL W+ F + + GV+Y++LRK+ Sbjct: 119 VRHPEWHLNSDYSYGFAYILAWVAFPLALLSGVIYVILRKR 159 >gi|4503561 epithelial membrane protein 2 [Homo sapiens] Length = 167 Score = 121 bits (303), Expect = 3e-28 Identities = 68/171 (39%), Positives = 98/171 (57%), Gaps = 19/171 (11%) Query: 1 MLVLLAGIFVVHIATVIMLFVSTIANVWLVSNTVDASVGLWKNCTNISCSDSL--SYASE 58 MLVLLA I HI + +LF++T+ N W V + A V W+ CTN + + S+ Sbjct: 1 MLVLLAFIIAFHITSAALLFIATVDNAWWVGDEFFADV--WRICTNNTNCTVINDSFQEY 58 Query: 59 DALKTVQAFMILSIIFCVIALLVFVFQLFTMEKGNRFFLSGATTLVCWLCILVGVSIYTS 118 L+ VQA MILS I C IA +FV QLF +++G RF L+ L+ LC+++ SIYT Sbjct: 59 STLQAVQATMILSTILCCIAFFIFVLQLFRLKQGERFVLTSIIQLMSCLCVMIAASIYTD 118 Query: 119 ------------HYANRDGTQYHHGYSYILGWICFCFSFIIGVLYLVLRKK 157 + R+G+ +GYSYIL W+ F +FI G++YL+LRK+ Sbjct: 119 RREDIHDKNAKFYPVTREGS---YGYSYILAWVAFACTFISGMMYLILRKR 166 >gi|4503563 epithelial membrane protein 3 [Homo sapiens] Length = 163 Score = 93.6 bits (231), Expect = 6e-20 Identities = 55/166 (33%), Positives = 91/166 (54%), Gaps = 13/166 (7%) Query: 1 MLVLLAGIFVVHIATVIMLFVSTIANVWLVSNTVDASVGLWKNCT--NISCSDSLSYASE 58 M +LL + +HI +I+LFV+T+ W + S+ LW +CT N + + + S SE Sbjct: 1 MSLLLLVVSALHILILILLFVATLDKSWWTLPGKE-SLNLWYDCTWNNDTKTWACSNVSE 59 Query: 59 DA-LKTVQAFMILSIIFCVIALLVFVFQLFTMEKGNRFFLSGATTLVCWLCILVGVSIYT 117 + LK VQ M+LS+I C ++ ++F+FQL+TM +G F+ +G L + + G IY Sbjct: 60 NGWLKAVQVLMVLSLILCCLSFILFMFQLYTMRRGGLFYATGLCQLCTSVAVFTGALIYA 119 Query: 118 SHYAN------RDGTQYHHGYSYILGWICFCFSFIIGVLYLVLRKK 157 H R G+ GY + L W+ F + + G++Y+ LRK+ Sbjct: 120 IHAEEILEKHPRGGS---FGYCFALAWVAFPLALVSGIIYIHLRKR 162 >gi|239747698 PREDICTED: similar to hCG1784039 [Homo sapiens] Length = 161 Score = 68.6 bits (166), Expect = 2e-12 Identities = 51/165 (30%), Positives = 81/165 (49%), Gaps = 21/165 (12%) Query: 1 MLVLLAGIFVVHIATVIMLFVSTIANVWLVSNTVDASVGLWKNCT-NISCS---DSLSYA 56 MLVLL HI + +LF++TI N W V N A V W+ CT N C+ DS Sbjct: 1 MLVLLTFTVAFHITSAALLFIATIDNAWWVGNEFFADV--WRICTKNTKCTVINDSFKEY 58 Query: 57 SEDALKTVQAFMILSIIFCVIALLVFVFQLFTMEKGNRFFLSGATTLVCWLCILVGVSIY 116 S + + ++ ++ A + ++ T L AT + +LC+++ SIY Sbjct: 59 SMGRARWLTP--VIPALWEAEACGLXGQEIETSLANIMKLLHHAT--MSYLCLMIAASIY 114 Query: 117 TS--------HYANRDGTQYHHGYSYILGWICFCFSFIIGVLYLV 153 T +Y ++G+ +GYSYIL W+ F F+FI ++YL+ Sbjct: 115 TDRRDETTDFYYLTKEGS---YGYSYILAWVAFAFTFISSMMYLI 156 >gi|239916002 lens intrinsic membrane protein 2, 19kDa isoform 2 [Homo sapiens] Length = 173 Score = 56.2 bits (134), Expect = 1e-08 Identities = 43/158 (27%), Positives = 74/158 (46%), Gaps = 19/158 (12%) Query: 7 GIFVVHIATVIMLFVSTIANVWLVSNTVD--ASVGLWKNCTNISC---SDSLSYASEDAL 61 G+F + T I+L V+ + W+ A GLW+ C C +DS++Y + Sbjct: 8 GLFCAWVGT-ILLVVAMATDHWMQYRLSGSFAHQGLWRYCLGNKCYLQTDSIAYWN---- 62 Query: 62 KTVQAFMILSIIFCVIALLVFVFQLF----TMEKGNRFFLSGATTLVCWLCILVGVSIYT 117 +AFMILS + C I+ ++ F T + +R F +G L +++ ++IYT Sbjct: 63 -ATRAFMILSAL-CAISGIIMGIMAFAHQPTFSRISRPFSAGIMFFSSTLFVVLALAIYT 120 Query: 118 S---HYANRDGTQYHHGYSYILGWICFCFSFIIGVLYL 152 + R + +SYILGW+ +F G+ Y+ Sbjct: 121 GVTVSFLGRRFGDWRFSWSYILGWVAVLMTFFAGIFYM 158 >gi|50345279 claudin 18 isoform 2 [Homo sapiens] Length = 261 Score = 49.3 bits (116), Expect = 1e-06 Identities = 48/184 (26%), Positives = 75/184 (40%), Gaps = 39/184 (21%) Query: 9 FVVHIATVIMLFVSTIANVW----LVSNTVDASV---GLWKNCTNIS-----CSDSLSYA 56 FVV + + + +T + W L +N V A GLW++C S C + Sbjct: 11 FVVSLIGIAGIIAATCMDQWSTQDLYNNPVTAVFNYQGLWRSCVRESSGFTECRGYFTLL 70 Query: 57 SEDA-LKTVQAFMILSIIFCVIALLVFVFQLFTME--------KGNRFFLSGATTLVCWL 107 A L+ V+A MI+ I+ I LLV +F L + K N SG +V L Sbjct: 71 GLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTLTSGIMFIVSGL 130 Query: 108 CILVGVSIY------------TSHYANRDG------TQYHHGYSYILGWICFCFSFIIGV 149 C + GVS++ + Y G T+Y G + +GW+ + I GV Sbjct: 131 CAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGWVAGGLTLIGGV 190 Query: 150 LYLV 153 + + Sbjct: 191 MMCI 194 >gi|7705961 claudin 18 isoform 1 [Homo sapiens] Length = 261 Score = 46.6 bits (109), Expect = 9e-06 Identities = 45/184 (24%), Positives = 73/184 (39%), Gaps = 39/184 (21%) Query: 9 FVVHIATVIMLFVSTIANVWLVSNTVDASV-------GLWKNCTNIS-----CSDSLSYA 56 F++ I + +T ++W + D V GLW++C S C + Sbjct: 11 FLLSILGLAGCIAATGMDMWSTQDLYDNPVTSVFQYEGLWRSCVRQSSGFTECRPYFTIL 70 Query: 57 SEDA-LKTVQAFMILSIIFCVIALLVFVFQLFTME--------KGNRFFLSGATTLVCWL 107 A L+ V+A MI+ I+ I LLV +F L + K N SG +V L Sbjct: 71 GLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTLTSGIMFIVSGL 130 Query: 108 CILVGVSIY------------TSHYANRDG------TQYHHGYSYILGWICFCFSFIIGV 149 C + GVS++ + Y G T+Y G + +GW+ + I GV Sbjct: 131 CAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGWVAGGLTLIGGV 190 Query: 150 LYLV 153 + + Sbjct: 191 MMCI 194 >gi|21361300 lens intrinsic membrane protein 2, 19kDa isoform 1 [Homo sapiens] Length = 215 Score = 43.5 bits (101), Expect = 7e-05 Identities = 28/104 (26%), Positives = 50/104 (48%), Gaps = 8/104 (7%) Query: 56 ASEDALKTVQAFMILSIIFCVIALLVFVFQLF----TMEKGNRFFLSGATTLVCWLCILV 111 A++ +AFMILS + C I+ ++ F T + +R F +G L +++ Sbjct: 98 ATQAYWNATRAFMILSAL-CAISGIIMGIMAFAHQPTFSRISRPFSAGIMFFSSTLFVVL 156 Query: 112 GVSIYTS---HYANRDGTQYHHGYSYILGWICFCFSFIIGVLYL 152 ++IYT + R + +SYILGW+ +F G+ Y+ Sbjct: 157 ALAIYTGVTVSFLGRRFGDWRFSWSYILGWVAVLMTFFAGIFYM 200 >gi|22748765 claudin domain containing 2 [Homo sapiens] Length = 167 Score = 42.7 bits (99), Expect = 1e-04 Identities = 36/147 (24%), Positives = 67/147 (45%), Gaps = 8/147 (5%) Query: 7 GIFVVHIATVIMLFVSTIANVWLVSNTVDASVGLWKNCTNISCSDSLSYASEDALKTVQA 66 GI + +A V+M+ +ST N W + + GLW+ C + CS S + L A Sbjct: 11 GILLSLVANVLMV-LSTATNYW--TRQQEGHSGLWQECNHGICS---SIPCQTTLAVTVA 64 Query: 67 FMILSIIFCVIALLVFVFQLFTMEKGNRFFLSGATTLVCWLCILVGVSIYTSHYANRDGT 126 M+L++ V+ +++ + + R + A + L +L + YT A ++ Sbjct: 65 CMVLAVGVGVVGMVMGLRIRCDEGESLRGQTTSAFLFLGGLLLLTALIGYTVKNAWKNNV 124 Query: 127 QYHHGYSYILGWICFCFSFIIGVLYLV 153 + +SY GW+ FS + G +L+ Sbjct: 125 FF--SWSYFSGWLALPFSILAGFCFLL 149 >gi|169163665 PREDICTED: similar to hCG1784039 [Homo sapiens] Length = 93 Score = 39.7 bits (91), Expect = 0.001 Identities = 15/35 (42%), Positives = 25/35 (71%), Gaps = 3/35 (8%) Query: 119 HYANRDGTQYHHGYSYILGWICFCFSFIIGVLYLV 153 +Y ++G+ +GYSYIL W+ F F+FI ++YL+ Sbjct: 57 YYLTKEGS---YGYSYILAWVAFAFTFISSMMYLI 88 Score = 38.9 bits (89), Expect = 0.002 Identities = 20/45 (44%), Positives = 25/45 (55%), Gaps = 2/45 (4%) Query: 1 MLVLLAGIFVVHIATVIMLFVSTIANVWLVSNTVDASVGLWKNCT 45 MLVLL HI + +LF++TI N W V N A V W+ CT Sbjct: 1 MLVLLTFTVAFHITSAALLFIATIDNAWWVGNEFFADV--WRICT 43 >gi|169163222 PREDICTED: hypothetical protein LOC391359 [Homo sapiens] Length = 93 Score = 39.7 bits (91), Expect = 0.001 Identities = 15/35 (42%), Positives = 25/35 (71%), Gaps = 3/35 (8%) Query: 119 HYANRDGTQYHHGYSYILGWICFCFSFIIGVLYLV 153 +Y ++G+ +GYSYIL W+ F F+FI ++YL+ Sbjct: 57 YYLTKEGS---YGYSYILAWVAFAFTFISSMMYLI 88 Score = 38.9 bits (89), Expect = 0.002 Identities = 20/45 (44%), Positives = 25/45 (55%), Gaps = 2/45 (4%) Query: 1 MLVLLAGIFVVHIATVIMLFVSTIANVWLVSNTVDASVGLWKNCT 45 MLVLL HI + +LF++TI N W V N A V W+ CT Sbjct: 1 MLVLLTFTVAFHITSAALLFIATIDNAWWVGNEFFADV--WRICT 43 >gi|5921465 claudin 10 isoform b [Homo sapiens] Length = 228 Score = 35.8 bits (81), Expect = 0.015 Identities = 44/176 (25%), Positives = 69/176 (39%), Gaps = 40/176 (22%) Query: 9 FVVHIATVIMLFVSTIANVWLVSNTVDASV--------GLWKNCTNIS-----CSDSLSY 55 F+V I+ +++ + + W VS T+D +V LWK C S C D S Sbjct: 11 FMVSISGWVLVSSTLPTDYWKVS-TIDGTVITTATYWANLWKACVTDSTGVSNCKDFPSM 69 Query: 56 ASEDALKTVQAFMILSIIFCVIALLVFVFQLFTME----------KGNRFFLSGATTLVC 105 + D +QA L I + +F LF M+ K L+G ++ Sbjct: 70 LALDGY--IQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIACLAGIVFILS 127 Query: 106 WLCILVGVSIYTSHYANRDGTQ----------YHHGYSYILGWICFCFSFIIGVLY 151 LC + G S+ YAN+ T+ Y G + +GW I GV++ Sbjct: 128 GLCSMTGCSL----YANKITTEFFDPLFVEQKYELGAALFIGWAGASLCIIGGVIF 179 >gi|122937323 transmembrane protein 202 [Homo sapiens] Length = 273 Score = 35.8 bits (81), Expect = 0.015 Identities = 27/131 (20%), Positives = 61/131 (46%), Gaps = 8/131 (6%) Query: 29 LVSNTVDASVGLWKNCTNISCSDSLSYASEDALKTVQAFMILSIIFCVIALLVFVFQLFT 88 ++ N ++ GLW C + C S + L+ +AF ++S+ F ++ L ++F + Sbjct: 84 VIKNGLELYAGLWTLCNHELCW-SHTPKPPYYLQYSRAFFLISV-FTILTGLGWLFSSWI 141 Query: 89 MEKG----NRFFLSGATTLVCWLCILVGVSIYTS--HYANRDGTQYHHGYSYILGWICFC 142 + +G N + + C+L+ ++++ + H+ RD + ++Y L W Sbjct: 142 LNRGSMTTNLDLKVSMLSFISATCLLLCLNLFVAQVHWHTRDAMESDLLWTYYLNWCSDI 201 Query: 143 FSFIIGVLYLV 153 F G++ L+ Sbjct: 202 FYMFAGIISLL 212 >gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo sapiens] Length = 1170 Score = 35.4 bits (80), Expect = 0.020 Identities = 18/53 (33%), Positives = 31/53 (58%), Gaps = 1/53 (1%) Query: 62 KTVQAFMILSIIFCVIALLVFVFQLFTMEKGNRFFLSGATTLVCWL-CILVGV 113 K V + + +IIFC + L F+ Q+F +E G + F + +L WL C+ +G+ Sbjct: 985 KNVFSGIYRNIIFCSVVLGTFICQIFIVEFGGKPFSCTSLSLSQWLWCLFIGI 1037 >gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo sapiens] Length = 1205 Score = 35.4 bits (80), Expect = 0.020 Identities = 18/53 (33%), Positives = 31/53 (58%), Gaps = 1/53 (1%) Query: 62 KTVQAFMILSIIFCVIALLVFVFQLFTMEKGNRFFLSGATTLVCWL-CILVGV 113 K V + + +IIFC + L F+ Q+F +E G + F + +L WL C+ +G+ Sbjct: 985 KNVFSGIYRNIIFCSVVLGTFICQIFIVEFGGKPFSCTSLSLSQWLWCLFIGI 1037 >gi|24586686 voltage-dependent calcium channel gamma-8 subunit [Homo sapiens] Length = 425 Score = 35.0 bits (79), Expect = 0.026 Identities = 30/106 (28%), Positives = 50/106 (47%), Gaps = 11/106 (10%) Query: 56 ASEDALKTVQAFMILSIIFCVIALLVFVFQLFT-MEKGNRFFLSGATTL--VCWLCILVG 112 ++E L+ V+A I I+ ++ LL V + + K R + GA L L ++G Sbjct: 117 SAEYLLRVVRASSIFPILSAILLLLGGVCVAASRVYKSKRNIILGAGILFVAAGLSNIIG 176 Query: 113 VSIYTSHYANRDGTQ--------YHHGYSYILGWICFCFSFIIGVL 150 V +Y S A G + Y +G+S+ G + F + +IGVL Sbjct: 177 VIVYISANAGEPGPKRDEEKKNHYSYGWSFYFGGLSFILAEVIGVL 222 >gi|183979973 claudin 19 isoform a [Homo sapiens] Length = 224 Score = 33.5 bits (75), Expect = 0.076 Identities = 29/122 (23%), Positives = 54/122 (44%), Gaps = 23/122 (18%) Query: 39 GLWKNCTN-----ISCS--DSLSYASEDALKTVQAFMILSIIFCVIALLVFVFQLFT--- 88 GLW +C + + C DSL A + +++ +A M+++++ +A+++ V + Sbjct: 49 GLWMSCASQSTGQVQCKLYDSL-LALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRV 107 Query: 89 -----MEKGNRFFLSGATTLVCWLCILVGVSIY----TSHYANRD---GTQYHHGYSYIL 136 + KG GA ++ LC L VS Y T + N +Y G + + Sbjct: 108 GDSNPIAKGRVAIAGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFV 167 Query: 137 GW 138 GW Sbjct: 168 GW 169 >gi|124107616 claudin 23 [Homo sapiens] Length = 292 Score = 33.5 bits (75), Expect = 0.076 Identities = 35/157 (22%), Positives = 62/157 (39%), Gaps = 24/157 (15%) Query: 16 VIMLFVSTIANVW-----LVSNTVDASV--GLWKNCTNISC-------SDSLSYASEDAL 61 +++ T+A W ++ VD + GLW C S +D Y + Sbjct: 18 LLLNLTGTLAPGWRLVKGFLNQPVDVELYQGLWDMCREQSSRERECGQTDQWGYFEAQPV 77 Query: 62 KTVQAFMILSIIFCVIALLVFVFQLFTMEKGNRFFLSGATTLVCWLCILVG---VSIYTS 118 +A M+ S+ V+ LL+ + + F L+G + +V ++ L+G VS Y Sbjct: 78 LVARALMVTSLAATVLGLLLASLGVRCWQDEPNFVLAGLSGVVLFVAGLLGLIPVSWYNH 137 Query: 119 HYANRD-------GTQYHHGYSYILGWICFCFSFIIG 148 +RD YS +LG++ C + G Sbjct: 138 FLGDRDVLPAPASPVTVQVSYSLVLGYLGSCLLLLGG 174 >gi|10938016 claudin 11 [Homo sapiens] Length = 207 Score = 33.5 bits (75), Expect = 0.076 Identities = 41/167 (24%), Positives = 68/167 (40%), Gaps = 24/167 (14%) Query: 9 FVVHIATVIMLFVSTIANVWLVS--------NTVD--ASVGLWKNCTNIS----CSDSLS 54 FV I + V+T N W+V+ +D S GLW +C + C + Sbjct: 11 FVTSFVGWIGVIVTTSTNDWVVTCGYTIPTCRKLDELGSKGLWADCVMATGLYHCKPLVD 70 Query: 55 YASEDA-LKTVQAFMILSIIFCVIALLVFVFQLFTMEKGN--------RFFLSGATTLVC 105 ++ +A MI + + + A+L+ + L + G R L+G ++ Sbjct: 71 ILILPGYVQACRALMIAASVLGLPAILLLLTVLPCIRMGQEPGVAKYRRAQLAGVLLILL 130 Query: 106 WLCILVGVSIYTSHYANRDGTQYHHGYSYILGWICFCFSFIIGVLYL 152 LC LV +I+ A+R+ T GYS GWI + G + L Sbjct: 131 ALCALVA-TIWFPVCAHRETTIVSFGYSLYAGWIGAVLCLVGGCVIL 176 >gi|183979975 claudin 19 isoform b [Homo sapiens] Length = 211 Score = 33.5 bits (75), Expect = 0.076 Identities = 29/122 (23%), Positives = 54/122 (44%), Gaps = 23/122 (18%) Query: 39 GLWKNCTN-----ISCS--DSLSYASEDALKTVQAFMILSIIFCVIALLVFVFQLFT--- 88 GLW +C + + C DSL A + +++ +A M+++++ +A+++ V + Sbjct: 49 GLWMSCASQSTGQVQCKLYDSL-LALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRV 107 Query: 89 -----MEKGNRFFLSGATTLVCWLCILVGVSIY----TSHYANRD---GTQYHHGYSYIL 136 + KG GA ++ LC L VS Y T + N +Y G + + Sbjct: 108 GDSNPIAKGRVAIAGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFV 167 Query: 137 GW 138 GW Sbjct: 168 GW 169 >gi|5174405 voltage-dependent calcium channel gamma-2 subunit [Homo sapiens] Length = 323 Score = 33.1 bits (74), Expect = 0.100 Identities = 23/97 (23%), Positives = 42/97 (43%), Gaps = 6/97 (6%) Query: 60 ALKTVQAFMILSIIFCVIALLVFVFQLFTMEKGNRFFLSGATTLVCWLCILVGVSIYTSH 119 A++ F ILS+I + L F + N +G + L ++G+ +Y S Sbjct: 100 AVRASSIFPILSVILLFMGGLCIAASEFYKTRHNIILSAGIFFVSAGLSNIIGIIVYISA 159 Query: 120 YA------NRDGTQYHHGYSYILGWICFCFSFIIGVL 150 A + Y +G+S+ G + F + ++GVL Sbjct: 160 NAGDPSKSDSKKNSYSYGWSFYFGALSFIIAEMVGVL 196 >gi|5729756 voltage-dependent calcium channel gamma-3 subunit [Homo sapiens] Length = 315 Score = 33.1 bits (74), Expect = 0.100 Identities = 23/96 (23%), Positives = 40/96 (41%), Gaps = 5/96 (5%) Query: 60 ALKTVQAFMILSIIFCVIALLVFVFQLFTMEKGNRFFLSGATTLVCWLCILVGVSIYTSH 119 A++ F ILS+ L F + N +G + L ++G+ +Y S Sbjct: 100 AVRASSVFPILSVTLLFFGGLCVAASEFHRSRHNVILSAGIFFVSAGLSNIIGIIVYISA 159 Query: 120 YANRDGTQ-----YHHGYSYILGWICFCFSFIIGVL 150 A G + Y +G+S+ G F + I+GV+ Sbjct: 160 NAGDPGQRDSKKSYSYGWSFYFGAFSFIIAEIVGVV 195 >gi|153792768 claudin 6 [Homo sapiens] Length = 220 Score = 32.0 bits (71), Expect = 0.22 Identities = 37/168 (22%), Positives = 65/168 (38%), Gaps = 38/168 (22%) Query: 6 AGIFVVHIATVIMLFVSTIAN----VWLVSNTVDASV--------GLWKNCTNISCSDSL 53 AG+ ++ + ++ +V+ + + +W V+ + S+ GLW +C + + + Sbjct: 4 AGMQILGVVLTLLGWVNGLVSCALPMWKVTAFIGNSIVVAQVVWEGLWMSCV-VQSTGQM 62 Query: 54 SYASEDALKTVQAFMILSIIFCVIALLVFVFQL---------------------FTMEKG 92 D+L + + + CVIALLV +F L + G Sbjct: 63 QCKVYDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTCVEEKDSKARLVLTSG 122 Query: 93 NRFFLSGATTL--VCWLCILVGVSIYTSHYANRDGTQYHHGYSYILGW 138 F +SG TL VCW + Y A + + G S LGW Sbjct: 123 IVFVISGVLTLIPVCWTAHAIIRDFYNPLVA--EAQKRELGASLYLGW 168 >gi|33598916 claudin 10 isoform a [Homo sapiens] Length = 226 Score = 32.0 bits (71), Expect = 0.22 Identities = 37/163 (22%), Positives = 58/163 (35%), Gaps = 34/163 (20%) Query: 19 LFVSTIANVWLVSNTVDASV-------GLWKNCTNISCSDSLSYASEDALKT---VQAFM 68 L +T +N W V+ + + GLW NC + K +QA Sbjct: 19 LVAATTSNEWKVTTRASSVITATWVYQGLWMNCAGNALGSFHCRPHFTIFKVAGYIQACR 78 Query: 69 ILSIIFCVIALLVFVFQLFTME----------KGNRFFLSGATTLVCWLCILVGVSIYTS 118 L I + +F LF M+ K L+G ++ LC + G S+ Sbjct: 79 GLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIACLAGIVFILSGLCSMTGCSL--- 135 Query: 119 HYANRDGTQ----------YHHGYSYILGWICFCFSFIIGVLY 151 YAN+ T+ Y G + +GW I GV++ Sbjct: 136 -YANKITTEFFDPLFVEQKYELGAALFIGWAGASLCIIGGVIF 177 >gi|231569235 claudin 10 isoform a_i1 [Homo sapiens] Length = 207 Score = 31.6 bits (70), Expect = 0.29 Identities = 36/160 (22%), Positives = 56/160 (35%), Gaps = 47/160 (29%) Query: 19 LFVSTIANVWLVSNTVDASV-------GLWKNCTNISCSDSLSYASEDALKTVQAFMILS 71 L +T +N W V+ + + GLW NC +QA L Sbjct: 19 LVAATTSNEWKVTTRASSVITATWVYQGLWMNCAGY----------------IQACRGLM 62 Query: 72 IIFCVIALLVFVFQLFTME----------KGNRFFLSGATTLVCWLCILVGVSIYTSHYA 121 I + +F LF M+ K L+G ++ LC + G S+ YA Sbjct: 63 IAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIACLAGIVFILSGLCSMTGCSL----YA 118 Query: 122 NRDGTQ----------YHHGYSYILGWICFCFSFIIGVLY 151 N+ T+ Y G + +GW I GV++ Sbjct: 119 NKITTEFFDPLFVEQKYELGAALFIGWAGASLCIIGGVIF 158 >gi|239756473 PREDICTED: transmembrane protein 114 [Homo sapiens] Length = 223 Score = 31.2 bits (69), Expect = 0.38 Identities = 36/151 (23%), Positives = 57/151 (37%), Gaps = 37/151 (24%) Query: 39 GLWKNCTNIS-CSD----------SLSYASEDALKTVQAFMIL---SIIFCVIA----LL 80 GLW+ C S C+ ++S +S L F+IL S+I V L Sbjct: 67 GLWRTCRVQSPCTPLMNPFRLENVTVSESSRQLLTMHGTFVILLPLSLILMVFGGMTGFL 126 Query: 81 VFVFQLFTMEKGNRFFLSGATTLVCWLCILVGVSIYTSHYANR--------------DGT 126 F+ Q + + L+G L + L G+S+Y ++ A D Sbjct: 127 SFLLQAYLL-----LLLTGILFLFGAMVTLAGISVYIAYSAAAFREALCLLEEKALLDQV 181 Query: 127 QYHHGYSYILGWICFCFSFIIGVLYLVLRKK 157 G+S LGWI F + G +L ++ Sbjct: 182 DISFGWSLALGWISFIAELLTGAAFLAAARE 212 >gi|239752599 PREDICTED: transmembrane protein 114, partial [Homo sapiens] Length = 217 Score = 31.2 bits (69), Expect = 0.38 Identities = 36/151 (23%), Positives = 57/151 (37%), Gaps = 37/151 (24%) Query: 39 GLWKNCTNIS-CSD----------SLSYASEDALKTVQAFMIL---SIIFCVIA----LL 80 GLW+ C S C+ ++S +S L F+IL S+I V L Sbjct: 61 GLWRTCRVQSPCTPLMNPFRLENVTVSESSRQLLTMHGTFVILLPLSLILMVFGGMTGFL 120 Query: 81 VFVFQLFTMEKGNRFFLSGATTLVCWLCILVGVSIYTSHYANR--------------DGT 126 F+ Q + + L+G L + L G+S+Y ++ A D Sbjct: 121 SFLLQAYLL-----LLLTGILFLFGAMVTLAGISVYIAYSAAAFREALCLLEEKALLDQV 175 Query: 127 QYHHGYSYILGWICFCFSFIIGVLYLVLRKK 157 G+S LGWI F + G +L ++ Sbjct: 176 DISFGWSLALGWISFIAELLTGAAFLAAARE 206 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.334 0.142 0.458 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 4,944,827 Number of Sequences: 37866 Number of extensions: 178859 Number of successful extensions: 936 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 16 Number of HSP's successfully gapped in prelim test: 33 Number of HSP's that attempted gapping in prelim test: 897 Number of HSP's gapped (non-prelim): 55 length of query: 157 length of database: 18,247,518 effective HSP length: 94 effective length of query: 63 effective length of database: 14,688,114 effective search space: 925351182 effective search space used: 925351182 T: 11 A: 40 X1: 15 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 39 (21.6 bits) S2: 57 (26.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.