Guide to the Human Genome
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Search of human proteins with 4503247

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4503247 ribosomal RNA processing 1 homolog [Homo sapiens]
         (461 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4503247 ribosomal RNA processing 1 homolog [Homo sapiens]          912   0.0  
gi|57863269 ribosomal RNA processing 1 homolog B [Homo sapiens]       391   e-109
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]            46   6e-05
gi|4759208 TAO kinase 2 isoform 1 [Homo sapiens]                       43   5e-04
gi|45505130 TAO kinase 2 isoform 2 [Homo sapiens]                      43   5e-04
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ...    43   7e-04
gi|41152097 DNA segment on chromosome X and Y (unique) 155 expre...    42   9e-04
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]           42   9e-04
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]           42   9e-04
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi...    42   0.001
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]            42   0.002
gi|48255931 hepatoma-derived growth factor-related protein 2 iso...    41   0.003
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         41   0.003
gi|14249158 hepatoma-derived growth factor-related protein 2 iso...    41   0.003
gi|122937227 U2-associated SR140 protein [Homo sapiens]                40   0.003
gi|148746195 trichohyalin [Homo sapiens]                               40   0.006
gi|24475863 H1 histone family, member O, oocyte-specific [Homo s...    40   0.006
gi|29568103 U1 small nuclear ribonucleoprotein 70 kDa [Homo sapi...    39   0.008
gi|52426743 cisplatin resistance-associated overexpressed protei...    39   0.008
gi|19923485 cisplatin resistance-associated overexpressed protei...    39   0.008
gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]            39   0.010
gi|14790190 spen homolog, transcriptional regulator [Homo sapiens]     39   0.010
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]           39   0.013
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]           39   0.013
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]           39   0.013
gi|122114651 ubiquitin specific peptidase 36 [Homo sapiens]            39   0.013
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]                       39   0.013
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa...    38   0.017
gi|239758013 PREDICTED: hypothetical protein [Homo sapiens]            37   0.029
gi|4826894 phosphodiesterase 1C [Homo sapiens]                         37   0.029

>gi|4503247 ribosomal RNA processing 1 homolog [Homo sapiens]
          Length = 461

 Score =  912 bits (2356), Expect = 0.0
 Identities = 461/461 (100%), Positives = 461/461 (100%)

Query: 1   MVSRVQLPPEIQLAQRLAGNEQVTRDRAVRKLRKYIVARTQRAAGGFTHDELLKVWKGLF 60
           MVSRVQLPPEIQLAQRLAGNEQVTRDRAVRKLRKYIVARTQRAAGGFTHDELLKVWKGLF
Sbjct: 1   MVSRVQLPPEIQLAQRLAGNEQVTRDRAVRKLRKYIVARTQRAAGGFTHDELLKVWKGLF 60

Query: 61  YCMWMQDKPLLQEELGRTISQLVHAFQTTEAQHLFLQAFWQTMNREWTGIDRLRLDKFYM 120
           YCMWMQDKPLLQEELGRTISQLVHAFQTTEAQHLFLQAFWQTMNREWTGIDRLRLDKFYM
Sbjct: 61  YCMWMQDKPLLQEELGRTISQLVHAFQTTEAQHLFLQAFWQTMNREWTGIDRLRLDKFYM 120

Query: 121 LMRMVLNESLKVLKMQGWEERQIEELLELLMTEILHPSSQAPNGVKSHFIEIFLEELTKV 180
           LMRMVLNESLKVLKMQGWEERQIEELLELLMTEILHPSSQAPNGVKSHFIEIFLEELTKV
Sbjct: 121 LMRMVLNESLKVLKMQGWEERQIEELLELLMTEILHPSSQAPNGVKSHFIEIFLEELTKV 180

Query: 181 GAEELTADQNLKFIDPFCRIAARTKDSLVLNNITRGIFETIVEQAPLAIEDLLNELDTQD 240
           GAEELTADQNLKFIDPFCRIAARTKDSLVLNNITRGIFETIVEQAPLAIEDLLNELDTQD
Sbjct: 181 GAEELTADQNLKFIDPFCRIAARTKDSLVLNNITRGIFETIVEQAPLAIEDLLNELDTQD 240

Query: 241 EEVASDSDESSEGGERGDALSQKRSEKPPAGSICRAEPEAGEEQAGDDRDSGGPVLQFDY 300
           EEVASDSDESSEGGERGDALSQKRSEKPPAGSICRAEPEAGEEQAGDDRDSGGPVLQFDY
Sbjct: 241 EEVASDSDESSEGGERGDALSQKRSEKPPAGSICRAEPEAGEEQAGDDRDSGGPVLQFDY 300

Query: 301 EAVANRLFEMASRQSTPSQNRKRLYKVIRKLQDLAGGIFPEDEIPEKACRRLLEGRRQKK 360
           EAVANRLFEMASRQSTPSQNRKRLYKVIRKLQDLAGGIFPEDEIPEKACRRLLEGRRQKK
Sbjct: 301 EAVANRLFEMASRQSTPSQNRKRLYKVIRKLQDLAGGIFPEDEIPEKACRRLLEGRRQKK 360

Query: 361 TKKQKRLLRLQQERGKGEKEPPSPGMERKRSRRRGVGADPEARAEAGEQPGTAERALLRD 420
           TKKQKRLLRLQQERGKGEKEPPSPGMERKRSRRRGVGADPEARAEAGEQPGTAERALLRD
Sbjct: 361 TKKQKRLLRLQQERGKGEKEPPSPGMERKRSRRRGVGADPEARAEAGEQPGTAERALLRD 420

Query: 421 QPRGRGQRGARQRRRTPRPLTSARAKAANVQEPEKKKKRRE 461
           QPRGRGQRGARQRRRTPRPLTSARAKAANVQEPEKKKKRRE
Sbjct: 421 QPRGRGQRGARQRRRTPRPLTSARAKAANVQEPEKKKKRRE 461


>gi|57863269 ribosomal RNA processing 1 homolog B [Homo sapiens]
          Length = 758

 Score =  391 bits (1004), Expect = e-109
 Identities = 215/471 (45%), Positives = 298/471 (63%), Gaps = 22/471 (4%)

Query: 8   PPEIQLAQRLAGNEQVTRDRAVRKLRKYIVARTQRAAGGFTHDELLKVWKGLFYCMWMQD 67
           P EIQ AQRLA +E+  RDRAV+KLR+YI  +TQR  GGF+ +ELLK+WKGLFYCMW+QD
Sbjct: 7   PAEIQFAQRLASSEKGIRDRAVKKLRQYISVKTQRETGGFSQEELLKIWKGLFYCMWVQD 66

Query: 68  KPLLQEELGRTISQLVHAFQTTEAQHLFLQAFWQTMNREWTGIDRLRLDKFYMLMRMVLN 127
           +PLLQEEL  TI+QLVHA   + AQHLF+Q FWQTMNREW GIDRLRLDK+YML+R+VL 
Sbjct: 67  EPLLQEELANTIAQLVHAVNNSAAQHLFIQTFWQTMNREWKGIDRLRLDKYYMLIRLVLR 126

Query: 128 ESLKVLKMQGWEERQIEELLELLMTEILHPSSQAPNGVKSHFIEIFLEELTKVGAEELTA 187
           +S +VLK  GWEE +I+  L++LM E+L P SQ+PNGV+ HFI+I+L+EL+KVG +EL A
Sbjct: 127 QSFEVLKRNGWEESRIKVFLDVLMKEVLCPESQSPNGVRFHFIDIYLDELSKVGGKELLA 186

Query: 188 DQNLKFIDPFCRIAARTKDSLVLNNITRGIFETIVEQAPLAIEDLLNELDTQ--DEEVAS 245
           DQNLKFIDPFC+IAA+TKD  ++  I RG+FE IV+Q+P   E+ + E  T+  D ++++
Sbjct: 187 DQNLKFIDPFCKIAAKTKDHTLVQTIARGVFEAIVDQSPFVPEETMEEQKTKVGDGDLSA 246

Query: 246 DSDESSEGGERGDALSQKRSEKPPAGSICRAEPEAGEEQAGDDRDSGGPVLQFDYEAVAN 305
           +    +E   R     +K +             E G +  G   D+ GP+LQFDY+AVA+
Sbjct: 247 EEIPENEVSLRRAVSKKKTALGKNHSRKDGLSDERGRDDCGTFEDT-GPLLQFDYKAVAD 305

Query: 306 RLFEMASRQSTPSQNRKRLYKVIRKLQDLAGG------IFPEDEIPEKACRRLLEGRRQK 359
           RL EM SR++TP  NRKRL K+I+K QDL+ G       F ED   ++  + L +G+ +K
Sbjct: 306 RLLEMTSRKNTPHFNRKRLSKLIKKFQDLSEGSSISQLSFAEDISADEDDQILSQGKHKK 365

Query: 360 KTKKQKRLLRLQQERGK-----GEKEPPSPGMERKRSRRRGVGADPEARAEAGEQPGTAE 414
           K  K      L++E+G       E++  S   +R+R +++     PE     G  P   +
Sbjct: 366 KGNKLLEKTNLEKEKGSRVFCVEEEDSESSLQKRRRKKKKKHHLQPENPGPGGAAPSLEQ 425

Query: 415 RALLRDQPRGRGQRGARQRRRTP-RPLTSARAKAANVQEP-----EKKKKR 459
                 +P   G +  + R   P    TS+  + +  + P       K+KR
Sbjct: 426 NR--GREPEASGLKALKARVAEPGAEATSSTGEESGSEHPPAVPMHNKRKR 474


>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 245

 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 33/114 (28%), Positives = 56/114 (49%), Gaps = 7/114 (6%)

Query: 354 EGRRQKKTKKQKRLLRLQQERGKGEKEPPSPGMERKRSRRRGVGADPEARAEAGEQPGTA 413
           EG+ +++ +++KR  R ++ER K E+E      ERK+  R+ VG   E R E  E+    
Sbjct: 129 EGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEK-ERKERK 187

Query: 414 ERALLRDQPRGRGQRGARQRRRTPRPLTSARAK------AANVQEPEKKKKRRE 461
           +R   R + +   +R  R+ R+  R     R K        N +E E+ K+ R+
Sbjct: 188 KRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERK 241



 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 36/122 (29%), Positives = 59/122 (48%), Gaps = 14/122 (11%)

Query: 341 EDEIPEKACRRLLEGRRQKKTKKQKRLLRLQQERGKGEKEPPSPGMERKRSRRRGVGADP 400
           E E   K  RR  E R++++ K++KR      ERGK EK+      ER+R +RR      
Sbjct: 54  ERESERKKERREREKRKREREKERKR------ERGKKEKKGERKKEERERKKRR-----R 102

Query: 401 EARAEAGEQPGTAERALLRDQPRGR-GQRGARQRRRTPRPLTSARAKAANVQEPEKKKKR 459
           E   + GE+    +R     + RGR  + G  + R+  R     + +    +E EK+++R
Sbjct: 103 EKENKEGEE--KEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERER 160

Query: 460 RE 461
           +E
Sbjct: 161 KE 162



 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 34/120 (28%), Positives = 59/120 (49%), Gaps = 10/120 (8%)

Query: 346 EKACRRLLEGRRQKKTK----KQKRLLRLQQERGKGEKEPPSPGMERKRSRRRGVGADPE 401
           +K  R   + RR+K+ K    K+KR  + ++ERG+  KE      ERK  R+R    + E
Sbjct: 91  KKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKE--GKERERKEERKREERKERE 148

Query: 402 ARAEAGEQPGTAERALLRDQPRGRGQRGARQRRRTPRPLTSARAKAANVQEPEKKKKRRE 461
            + E  E+    ER     + R R Q G ++  R  +     + +  N +E +K+++R+E
Sbjct: 149 RKKEEREK----ERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKE 204



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 31/115 (26%), Positives = 56/115 (48%), Gaps = 17/115 (14%)

Query: 356 RRQKKTKKQKRLLRLQQERGKGEKEPPSPGMERKRSRRR-------GVGADPEARAEAGE 408
           RR+++ +K++R    ++ERGK EK+      ER+R +RR       G   +   + E  E
Sbjct: 63  RREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKE 122

Query: 409 QPGTAERALLRD--QPRGRGQRGARQRRRTPRPLTSARAKAANVQEPEKKKKRRE 461
           +  T++    R+  + R R +R  R+R++  R     R         E+KK+ R+
Sbjct: 123 RGRTSKEGKERERKEERKREERKERERKKEEREKERERK--------ERKKRERK 169



 Score = 37.4 bits (85), Expect = 0.029
 Identities = 25/108 (23%), Positives = 50/108 (46%), Gaps = 1/108 (0%)

Query: 354 EGRRQKKTKKQKRLLRLQQERGKGEKEPPSPGMERKRSRRRGVGADPEARAEAGEQPGTA 413
           E  R+ +T+K+ +  R + ER K  +E      ER++ R+R  G   +      E+    
Sbjct: 40  EREREIETRKEGKKER-ESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERK 98

Query: 414 ERALLRDQPRGRGQRGARQRRRTPRPLTSARAKAANVQEPEKKKKRRE 461
           +R   ++   G  +   +++ +  R  TS   K    +E  K+++R+E
Sbjct: 99  KRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKE 146



 Score = 35.0 bits (79), Expect = 0.14
 Identities = 37/181 (20%), Positives = 78/181 (43%), Gaps = 9/181 (4%)

Query: 255 ERGDALSQKRSEKPPAGSICRAEPEAGEEQAGDDRDSGGPVLQFDYEAVANRLFEMASRQ 314
           ER     ++R +K   G   + E E  + +   +   G        E    +  E   R 
Sbjct: 72  EREKERKRERGKKEKKGERKKEERERKKRRREKENKEGE-------EKEKRKKKEKKERG 124

Query: 315 STPSQNRKRLYKVIRKLQDLAGGIFPEDEIPEKACRRLLEGRRQKKT--KKQKRLLRLQQ 372
            T  + ++R  K  RK ++       ++E  ++  R+  + R +K+   K+++R  + ++
Sbjct: 125 RTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERK 184

Query: 373 ERGKGEKEPPSPGMERKRSRRRGVGADPEARAEAGEQPGTAERALLRDQPRGRGQRGARQ 432
           ER K E+       ER+R  RR    + + + E  ++     +   R++ RG+ +R  R+
Sbjct: 185 ERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERK 244

Query: 433 R 433
           +
Sbjct: 245 K 245


>gi|4759208 TAO kinase 2 isoform 1 [Homo sapiens]
          Length = 1049

 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 53/232 (22%), Positives = 95/232 (40%), Gaps = 19/232 (8%)

Query: 239 QDEEVASDSDESSEGGERGDALSQKRSEKPPAGSICRAEPEAGEEQAGDDRDSGGPVLQF 298
           ++EE   + +E  EG E  +    +  E              G +   DD         +
Sbjct: 379 EEEEEEEEEEEEEEGPEAREMAMMQEGEHTVTSHSSIIHRLPGSDNLYDD--------PY 430

Query: 299 DYEAVANRLFEMASRQ--STPSQNRKRLYKVIR------KLQDLAGGIFPEDEIPEKACR 350
             E   + L   A+    ST S  R+R Y   R      +   L      E E  + A R
Sbjct: 431 QPEITPSPLQPPAAPAPTSTTSSARRRAYCRNRDHFATIRTASLVSRQIQEHE-QDSALR 489

Query: 351 RLLEGRRQKKTKKQKRLLRLQQERGKGEKEPPSPGMERK-RSRRRGVGADPEARAEAGEQ 409
             L G ++ + + QK+LL L+  R +GE+E  S  ++R+  ++R G GA+ E  A   + 
Sbjct: 490 EQLSGYKRMRRQHQKQLLALES-RLRGEREEHSARLQRELEAQRAGFGAEAEKLARRHQA 548

Query: 410 PGTAERALLRDQPRGRGQRGARQRRRTPRPLTSARAKAANVQEPEKKKKRRE 461
            G  E    + + R   Q    Q+++    L  A+ +   +++ + K++ +E
Sbjct: 549 IGEKEARAAQAEERKFQQHILGQQKKELAALLEAQKRTYKLRKEQLKEELQE 600


>gi|45505130 TAO kinase 2 isoform 2 [Homo sapiens]
          Length = 1235

 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 53/232 (22%), Positives = 95/232 (40%), Gaps = 19/232 (8%)

Query: 239 QDEEVASDSDESSEGGERGDALSQKRSEKPPAGSICRAEPEAGEEQAGDDRDSGGPVLQF 298
           ++EE   + +E  EG E  +    +  E              G +   DD         +
Sbjct: 379 EEEEEEEEEEEEEEGPEAREMAMMQEGEHTVTSHSSIIHRLPGSDNLYDD--------PY 430

Query: 299 DYEAVANRLFEMASRQ--STPSQNRKRLYKVIR------KLQDLAGGIFPEDEIPEKACR 350
             E   + L   A+    ST S  R+R Y   R      +   L      E E  + A R
Sbjct: 431 QPEITPSPLQPPAAPAPTSTTSSARRRAYCRNRDHFATIRTASLVSRQIQEHE-QDSALR 489

Query: 351 RLLEGRRQKKTKKQKRLLRLQQERGKGEKEPPSPGMERK-RSRRRGVGADPEARAEAGEQ 409
             L G ++ + + QK+LL L+  R +GE+E  S  ++R+  ++R G GA+ E  A   + 
Sbjct: 490 EQLSGYKRMRRQHQKQLLALES-RLRGEREEHSARLQRELEAQRAGFGAEAEKLARRHQA 548

Query: 410 PGTAERALLRDQPRGRGQRGARQRRRTPRPLTSARAKAANVQEPEKKKKRRE 461
            G  E    + + R   Q    Q+++    L  A+ +   +++ + K++ +E
Sbjct: 549 IGEKEARAAQAEERKFQQHILGQQKKELAALLEAQKRTYKLRKEQLKEELQE 600


>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
           sapiens]
          Length = 600

 Score = 42.7 bits (99), Expect = 7e-04
 Identities = 33/125 (26%), Positives = 60/125 (48%), Gaps = 4/125 (3%)

Query: 341 EDEIPEKACRRLLEGRRQKKTKKQKRLLRLQQERGKGEKEPPSPGMERKRSRRRGVGADP 400
           E E   K  RR  + R +K+ + ++R    ++ER +          E++R+R++    + 
Sbjct: 72  ERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERET 131

Query: 401 EARAEAG---EQPGTAERALLRDQPRGRGQRGARQR-RRTPRPLTSARAKAANVQEPEKK 456
           E   E G   +  G  ER   RD  + R ++  R+R R+T R     R +  N QE  ++
Sbjct: 132 EREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRER 191

Query: 457 KKRRE 461
           +++RE
Sbjct: 192 ERQRE 196



 Score = 37.0 bits (84), Expect = 0.038
 Identities = 37/143 (25%), Positives = 60/143 (41%), Gaps = 19/143 (13%)

Query: 326 KVIRKLQDLAGGIFPEDEIPEKACRRLLEGRRQKKTKKQKRLLRLQQERGKGEKEPPSPG 385
           K++    D  G ++ E  IP      L   RR+  +++  R       RG G+    + G
Sbjct: 4   KIVPATADQLGTLWVEVTIP------LDFSRRRPGSQESPR------RRGLGQAHKDADG 51

Query: 386 MERKRSRRRGVGADPEARAEAGEQPGTAERALLRDQPRGRGQRGARQR-------RRTPR 438
            +R+R+R++      E R    E     ER   +D+ R R +   RQR       R+T R
Sbjct: 52  DDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDR 111

Query: 439 PLTSARAKAANVQEPEKKKKRRE 461
                R K  N Q+  +++  RE
Sbjct: 112 ERDRQREKERNRQKERERETERE 134



 Score = 36.2 bits (82), Expect = 0.064
 Identities = 32/122 (26%), Positives = 53/122 (43%), Gaps = 11/122 (9%)

Query: 346 EKACRRLLEGRRQKKT-------KKQKRLLRLQQERGKGEKEPPSPGMERKRSRRRGVGA 398
           +K   R  + +RQ++T       +K++R    ++ER +  K       ER+R R+R    
Sbjct: 276 QKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETER 335

Query: 399 DPEARAEAGEQPGTAERALLRDQPRGRGQRGARQ-RRRTPRPLTSARAKAANVQEPEKKK 457
           D E   E   +  T    + R++ R  G+ G RQ  R   R     R  A   +E E+ +
Sbjct: 336 DREKERERKRKRQT---EMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDR 392

Query: 458 KR 459
            R
Sbjct: 393 DR 394



 Score = 34.3 bits (77), Expect = 0.24
 Identities = 28/125 (22%), Positives = 53/125 (42%), Gaps = 5/125 (4%)

Query: 341 EDEIPEKACRRLLEGRRQKKTKKQKRLLRLQQER----GKGEKEPPSPGMERKRSRRRGV 396
           E E   +  R     R +++ +K+KR   + +ER    G+  +       ER+R R R  
Sbjct: 322 ERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQS 381

Query: 397 GADPEARAEAGEQPGTAERALLRDQPRGRGQRGARQRRRTPRPLTSARAKAANVQEPEKK 456
             + E R    ++    ER    ++ R  GQR   ++R   +   S R +    +  ++K
Sbjct: 382 AREREERERDRDRDRQKERERQTEKDRD-GQRETEKQREREKDRESERGRERGREREKQK 440

Query: 457 KKRRE 461
            + R+
Sbjct: 441 GRERD 445



 Score = 33.5 bits (75), Expect = 0.42
 Identities = 29/120 (24%), Positives = 53/120 (44%), Gaps = 17/120 (14%)

Query: 341 EDEIPEKACRRLLEGRRQKKTKKQKRLLRLQQERGKGEKEPPSPGMERKRSRRRGVGADP 400
           ED   E+   R  E   + +T+++++  R +  + K E+E      ER+R+  R    D 
Sbjct: 202 EDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQA-ERERASERETERDK 260

Query: 401 EARAEAGEQPGTAERALLRDQPRGRGQRGARQRRRTPRPLTSARAKAANVQEPEKKKKRR 460
           E   E             RD+ R R +R   + R+T R     + +    +E E+K++R+
Sbjct: 261 ERERE-------------RDRDRDRDRRQKERERQTDR---KRQRRTERDRETERKRERQ 304



 Score = 33.5 bits (75), Expect = 0.42
 Identities = 49/228 (21%), Positives = 93/228 (40%), Gaps = 30/228 (13%)

Query: 235 ELDTQDE-EVASDSDESSEGGERGDALSQKRSEKPPAGSICRAEPEAGEEQAGDDRDSGG 293
           E +T+ E E    +D   +   + +   +K++E+  A    R      E +   DRD   
Sbjct: 215 ERETETETERKRQTDRERDRQRKTEREREKQAERERASE--RETERDKERERERDRDRDR 272

Query: 294 PVLQFDYEAVANRLFEMASRQSTPSQNRKRLYKVIRKLQDLAGGIFPEDEIPEKACRRLL 353
              Q + E   +R      RQ    ++R+   K  R+ +         +   E+  +R  
Sbjct: 273 DRRQKERERQTDR-----KRQRRTERDRETERKRERQRE--------RERERERNRKRER 319

Query: 354 EGRRQKKTKKQKRLLRLQQERGKGEKEPPSPGMERKRSRRRGVGADPEARAEAGEQPGTA 413
           E  R+++ ++Q+   R  +E+ +  K      M+R+R+R+ G     E R +A  +    
Sbjct: 320 ERERERERERQRETER-DREKERERKRKRQTEMDRERNRQTG----REGRRQAERE---- 370

Query: 414 ERALLRDQPRGRGQRGARQRRRTPRPLTSARAKAANVQEPEKKKKRRE 461
                R++ R R ++ AR+R    R     R K    Q  + +  +RE
Sbjct: 371 -----RERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRE 413



 Score = 32.7 bits (73), Expect = 0.71
 Identities = 28/110 (25%), Positives = 48/110 (43%), Gaps = 15/110 (13%)

Query: 350 RRLLEGRRQKKTKKQKRLLRLQQERGKGEKEPPSPGMERKRSRRRGVGADPEARAEAGEQ 409
           +R  E  RQK+ +++K     +QER + E++         R   RG   + E   E    
Sbjct: 168 QRQTERNRQKEREREKN----RQERRERERQREKENKTEDRHSERGRERERERETET--- 220

Query: 410 PGTAERALLRDQPRGRGQRGARQRRRTPRPLTSARAKAANVQEPEKKKKR 459
               ER    D+ R R ++  R+R +       A  + A+ +E E+ K+R
Sbjct: 221 --ETERKRQTDRERDRQRKTEREREK------QAERERASERETERDKER 262


>gi|41152097 DNA segment on chromosome X and Y (unique) 155
           expressed sequence isoform 1 [Homo sapiens]
          Length = 695

 Score = 42.4 bits (98), Expect = 9e-04
 Identities = 45/164 (27%), Positives = 78/164 (47%), Gaps = 14/164 (8%)

Query: 299 DYEAVANRL---FEMASRQSTPSQNRKRLYKVIRKLQDLAGGIFPEDEIPEKACRRLLEG 355
           D +AVA  +   F+     S  S  +++L +  +KLQ+L      +    +K   +  E 
Sbjct: 245 DGKAVACNIKVSFDSTKHLSDASIKKRQLER--QKLQELE-----QQREEQKRREKEAEE 297

Query: 356 RRQKKTKKQKRLLRLQQERGKGEKEPPSPGMERKRSRRRGVGADPEARAEAGEQPGTAER 415
           R++ + +KQK L  L++ER + EK       +R R  RR      + +AE  EQ    E+
Sbjct: 298 RQRAEERKQKELEELERERKREEKLRKREQKQRDRELRRNQKKLEKLQAE--EQKQLQEK 355

Query: 416 ALLRDQPRGRGQRGARQRRRTPRPLTSARAKAANVQEPEKKKKR 459
             L ++     QR  +  R     L  +RAKA  ++E E+K+++
Sbjct: 356 IKLEERKLLLAQRNLQSIRLIAELL--SRAKAVKLREQEQKEEK 397



 Score = 29.6 bits (65), Expect = 6.0
 Identities = 28/134 (20%), Positives = 49/134 (36%), Gaps = 11/134 (8%)

Query: 338 IFPEDEIPEKACRRLLEGRRQKKTKKQKRLLRLQQERGKGEKEPPSPGMERKRSRRRGVG 397
           + PED  PEK C   +        ++ K +   +Q   + +         R+ S+ RG  
Sbjct: 531 VVPEDGSPEKRCPGGVLSCIPDNNQQPKGIPACEQNVSRKDTRSEQDKCNREPSKGRGRA 590

Query: 398 ADPEARAEAGEQPGTAERALLRDQPRGRGQR-----------GARQRRRTPRPLTSARAK 446
                      +   A RA  R+  R R +R             R+R  +P    S R+ 
Sbjct: 591 TGDGLADRHKRERSRARRASSREDGRPRKERRPHKKHAYKDDSPRRRSTSPDHTRSRRSH 650

Query: 447 AANVQEPEKKKKRR 460
           + +    E+ ++RR
Sbjct: 651 SKDRHRRERSRERR 664


>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
          Length = 2426

 Score = 42.4 bits (98), Expect = 9e-04
 Identities = 58/269 (21%), Positives = 108/269 (40%), Gaps = 24/269 (8%)

Query: 204  TKDSLVLNNITRGIFETIVEQAPLAIEDLLNELDTQDEEVASDSDESSEGGERGDALSQK 263
            T+  +V++    G  E  +E  PL  +D+  +L + +  V+ D++E     E    L+  
Sbjct: 1637 TEHDMVISTSPSGGSEADIE-GPLPAKDIHLDLPSNNNLVSKDTEEPLPVKESDQTLAAL 1695

Query: 264  RSEKPPAGSICRAEPEAGEEQAG----------DDRDSGGPVLQFDYEAVANRL--FEMA 311
             S K  +G      P   E              ++ D   P+L  D E + +     E  
Sbjct: 1696 LSPKESSGGEKEVPPPPKETLPDSGFSANIEDINEADLVRPLLPKDMERLTSLRAGIEGP 1755

Query: 312  SRQSTPSQNRKRLYKVIRKLQDLAGGIFPEDEIPEKACRRLLEGRRQKKTKKQKRLLRLQ 371
               S   ++R     V+  + + A     E++   +   ++ +    +K+KK K      
Sbjct: 1756 LLASDVGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKD--THEKSKKNKN----- 1808

Query: 372  QERGKGEKEPPSPGMERKRSRRRGVGADPEARAEAGEQPGTAERALLRDQPRGRGQRGAR 431
              R KGEKE       R RS +R   ++ ++R    E    A +   + +   R Q  +R
Sbjct: 1809 --RDKGEKEKKRDSSLRSRS-KRSKSSEHKSRKRTSESRSRARKRSSKSKSH-RSQTRSR 1864

Query: 432  QRRRTPRPLTSARAKAANVQEPEKKKKRR 460
             R R  R  + +R+K+   +   K+K++R
Sbjct: 1865 SRSRRRRRSSRSRSKSRGRRSVSKEKRKR 1893


>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
          Length = 2303

 Score = 42.4 bits (98), Expect = 9e-04
 Identities = 58/269 (21%), Positives = 108/269 (40%), Gaps = 24/269 (8%)

Query: 204  TKDSLVLNNITRGIFETIVEQAPLAIEDLLNELDTQDEEVASDSDESSEGGERGDALSQK 263
            T+  +V++    G  E  +E  PL  +D+  +L + +  V+ D++E     E    L+  
Sbjct: 1637 TEHDMVISTSPSGGSEADIE-GPLPAKDIHLDLPSNNNLVSKDTEEPLPVKESDQTLAAL 1695

Query: 264  RSEKPPAGSICRAEPEAGEEQAG----------DDRDSGGPVLQFDYEAVANRL--FEMA 311
             S K  +G      P   E              ++ D   P+L  D E + +     E  
Sbjct: 1696 LSPKESSGGEKEVPPPPKETLPDSGFSANIEDINEADLVRPLLPKDMERLTSLRAGIEGP 1755

Query: 312  SRQSTPSQNRKRLYKVIRKLQDLAGGIFPEDEIPEKACRRLLEGRRQKKTKKQKRLLRLQ 371
               S   ++R     V+  + + A     E++   +   ++ +    +K+KK K      
Sbjct: 1756 LLASDVGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKD--THEKSKKNKN----- 1808

Query: 372  QERGKGEKEPPSPGMERKRSRRRGVGADPEARAEAGEQPGTAERALLRDQPRGRGQRGAR 431
              R KGEKE       R RS +R   ++ ++R    E    A +   + +   R Q  +R
Sbjct: 1809 --RDKGEKEKKRDSSLRSRS-KRSKSSEHKSRKRTSESRSRARKRSSKSKSH-RSQTRSR 1864

Query: 432  QRRRTPRPLTSARAKAANVQEPEKKKKRR 460
             R R  R  + +R+K+   +   K+K++R
Sbjct: 1865 SRSRRRRRSSRSRSKSRGRRSVSKEKRKR 1893


>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 123

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 30/107 (28%), Positives = 52/107 (48%), Gaps = 15/107 (14%)

Query: 354 EGRRQKKTKKQKRLLRLQQERGKGEKEPPSPGMERKRSRRRGVGADPEARAEAGEQPGTA 413
           EG+R++K K++++    +++  + EK       E+KR R+R    + E R E  E+    
Sbjct: 26  EGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREE--EEEEEE 83

Query: 414 ERALLRDQPRGRGQRGARQRRRTPRPLTSARAKAANVQEPEKKKKRR 460
           E     ++  GR ++  ++RRR               +E EKKKKRR
Sbjct: 84  EEKEEEEKEEGRRRKKKKKRRR-------------KEEEEEKKKKRR 117



 Score = 32.7 bits (73), Expect = 0.71
 Identities = 27/86 (31%), Positives = 40/86 (46%), Gaps = 15/86 (17%)

Query: 309 EMASRQSTPSQNRKRLYKVIRKLQDLAGGIFPEDEIPEKACRRLLEGRRQKKTKKQKRLL 368
           E   R+    + +KR  K  +K ++       E+E  EK      EGRR+KK KK++R  
Sbjct: 48  ETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRR-- 105

Query: 369 RLQQERGKGEKEPPSPGMERKRSRRR 394
                  K E+E      E+K+ RRR
Sbjct: 106 -------KEEEE------EKKKKRRR 118



 Score = 29.3 bits (64), Expect = 7.9
 Identities = 25/103 (24%), Positives = 47/103 (45%), Gaps = 11/103 (10%)

Query: 359 KKTKKQKRLLRLQQERGKGEKEPPSPGMERKRSRRRGVGADPEARAEAGEQPGTAERALL 418
           KK KK+K+     +E  + E+E    G +RK  R+       E R E  ++  T E    
Sbjct: 1   KKKKKKKKETEETEETEETEEEEEKEG-KRKEKRK-------EKRKEKEKKKKTKETEKR 52

Query: 419 RDQPRGRGQRGARQRRRTPRPLTSARAKAANVQEPEKKKKRRE 461
           +++     +   R+R+R  +     R +    +E EK+++ +E
Sbjct: 53  KEKEE---EEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKE 92


>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 275

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 30/118 (25%), Positives = 55/118 (46%), Gaps = 2/118 (1%)

Query: 346 EKACRRLLEGRRQKKTKKQKRLLRLQQERGKGEKEPPSPGMERKRSRRRGVGADPEARAE 405
           E+   R  E  +++K K++KR    ++ER + E+E        K  R+R        R +
Sbjct: 49  EREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQ 108

Query: 406 AG--EQPGTAERALLRDQPRGRGQRGARQRRRTPRPLTSARAKAANVQEPEKKKKRRE 461
            G  E+    ER     + + R +R  ++RR+  R     R K    +E ++KK+++E
Sbjct: 109 RGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKE 166



 Score = 39.7 bits (91), Expect = 0.006
 Identities = 30/109 (27%), Positives = 55/109 (50%), Gaps = 5/109 (4%)

Query: 356 RRQKKTKKQKRLLRLQQERGKGEKEPPSP---GMERKRSRRRGVGADPEARAEAGEQPGT 412
           RR+++ +K++R    ++ERGK EK+       G ER+R R+       E R E   +   
Sbjct: 40  RREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKE-RREKERRKRK 98

Query: 413 AERALLRDQPRGRGQRGARQRRRTPRPLTSARAKAANVQEPEKKKKRRE 461
            E+     + RGR +R  +++ R  R   + + +    ++  KKK+R+E
Sbjct: 99  KEKKKRERKQRGRRER-KKKKERKERERENKQRRERKRKKRRKKKRRKE 146



 Score = 37.7 bits (86), Expect = 0.022
 Identities = 33/163 (20%), Positives = 69/163 (42%), Gaps = 10/163 (6%)

Query: 309 EMASRQSTPSQNRKRLYKVIRKLQDLAGGIFPEDEIPEKACRRLLEGRRQKKTKKQKRLL 368
           E   R+    + R+R  K  +K +    G   E +  E+  +R     ++++ +K+++  
Sbjct: 44  EKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKK 103

Query: 369 RLQQERGKGEKEPPSPGMER----------KRSRRRGVGADPEARAEAGEQPGTAERALL 418
           R +++RG+ E++      ER          KR +RR      E + E        +R   
Sbjct: 104 RERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKR 163

Query: 419 RDQPRGRGQRGARQRRRTPRPLTSARAKAANVQEPEKKKKRRE 461
           + + R + +   R+ R+  R     R +    ++  +KKK R+
Sbjct: 164 KKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERK 206



 Score = 36.6 bits (83), Expect = 0.049
 Identities = 23/91 (25%), Positives = 45/91 (49%), Gaps = 1/91 (1%)

Query: 371 QQERGKGEKEPPSPGMERKRSRRRGVGADPEARAEAGEQPGTAERALLRDQPRGRGQRGA 430
           + ER K  +E      ER++ R+R  G   + + +  E+    ER   +++ + R +R  
Sbjct: 33  ESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKR-KEREKQRKERRE 91

Query: 431 RQRRRTPRPLTSARAKAANVQEPEKKKKRRE 461
           ++RR+  +       K    +E +KKK+R+E
Sbjct: 92  KERRKRKKEKKKRERKQRGRRERKKKKERKE 122



 Score = 35.8 bits (81), Expect = 0.084
 Identities = 27/111 (24%), Positives = 52/111 (46%), Gaps = 9/111 (8%)

Query: 356 RRQKKTKKQKRLLRLQQERGKGEKEPPSPGMERKRSRRRGVGADPEARAEAGEQPGTAER 415
           +R+ + KK++R    ++   + E++      E+K+ ++R  G + E + +  E+     R
Sbjct: 31  QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90

Query: 416 ALLR------DQPRGRGQRGARQRRRTPRPLTSARAKAANVQEPEKKKKRR 460
              R       + R R QRG R+R++        R    N Q  E+K+K+R
Sbjct: 91  EKERRKRKKEKKKRERKQRGRRERKKKKERKERER---ENKQRRERKRKKR 138



 Score = 30.0 bits (66), Expect = 4.6
 Identities = 30/132 (22%), Positives = 57/132 (43%), Gaps = 8/132 (6%)

Query: 309 EMASRQSTPSQNRKRLYKVIRKLQDLAGGIFPEDEIPEKACRRLLEGRRQKKTKKQKRLL 368
           E   ++    + RKR  +  ++ +   G    + +   K   R  + RR++K KK+++  
Sbjct: 83  EKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKK 142

Query: 369 R-----LQQERGKGE---KEPPSPGMERKRSRRRGVGADPEARAEAGEQPGTAERALLRD 420
           R      ++ERGK E   K+      E+KR R R        R E  E+    ++   + 
Sbjct: 143 RRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKK 202

Query: 421 QPRGRGQRGARQ 432
           + R + ++  RQ
Sbjct: 203 KERKKDRKTDRQ 214


>gi|48255931 hepatoma-derived growth factor-related protein 2
           isoform 1 [Homo sapiens]
          Length = 671

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 68/294 (23%), Positives = 113/294 (38%), Gaps = 63/294 (21%)

Query: 203 RTKDSLVLNNITRGIFETIVEQAPLAIEDLLNELDTQDEEVASDSDESSEGGERGDALSQ 262
           ++ D+  L   T  +  ++ ++A  A  DL     +  EE  S+S   SE     D   +
Sbjct: 148 KSSDNSGLKRKTPALKMSVSKRARKASSDLDQASVSPSEEENSESSSESEKTSDQDFTPE 207

Query: 263 KRS------EKPPAGSICRAEPEAGEEQAGDDRDSGGPVLQFDYEAVANRLFEMASRQST 316
           K++        P  G   +  P A +  +  D D   P    +  A+A      +S  S+
Sbjct: 208 KKAAVRAPRRGPLGGRKKKKAPSASDSDSKADSDGAKP----EPVAMARSASSSSSSSSS 263

Query: 317 ---------PSQNRKRLYKVIRKLQDLAGGIFPEDEIP---------------------- 345
                    P + RK   K + K +    G  P+ E P                      
Sbjct: 264 SDSDVSVKKPPRGRKPAEKPLPKPR----GRKPKPERPPSSSSSDSDSDEVDRISEWKRR 319

Query: 346 EKACRRLLEGRRQKKTKKQKRLLRLQQERGKGEKEPPSPGMERKRSRRRGVGADPEARAE 405
           ++A RR LE RR+++ +++ R LR Q++  K          ER+R R     AD   R E
Sbjct: 320 DEARRRELEARRRREQEEELRRLREQEKEEK----------ERRRER-----AD---RGE 361

Query: 406 AGEQPGTAERALLRDQPRGRGQRGARQRRRTPRPLTSARAKAANVQEPEKKKKR 459
           A    G +    LR+      +RG + R R P   + +  +A   +E +K  K+
Sbjct: 362 AERGSGGSSGDELREDDEPVKKRGRKGRGRGPPSSSDSEPEAELEREAKKSAKK 415



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 50/222 (22%), Positives = 87/222 (39%), Gaps = 36/222 (16%)

Query: 244 ASDSDESSEGGERGDALSQKRSEKPPAGSICRAEPEAGEEQAGDDRDSGGPVLQFDYEAV 303
           +SDSD S +   RG   ++K   KP      + +PE     +  D DS            
Sbjct: 263 SSDSDVSVKKPPRGRKPAEKPLPKPRGR---KPKPERPPSSSSSDSDSDE---------- 309

Query: 304 ANRLFEMASRQSTPSQNRKRLYKVIRKLQDLAGGIFPEDEIPEKACRRLLEGRRQKKTKK 363
            +R+ E   R       R+R  +  R+ +             E+  RRL E  +++K ++
Sbjct: 310 VDRISEWKRRDEA----RRRELEARRRREQ------------EEELRRLREQEKEEKERR 353

Query: 364 QKRLLRLQQERGKGE------KEPPSPGMER-KRSRRRGVGADPEARAEAGEQPGTAERA 416
           ++R  R + ERG G       +E   P  +R ++ R RG  +  ++  EA  +    + A
Sbjct: 354 RERADRGEAERGSGGSSGDELREDDEPVKKRGRKGRGRGPPSSSDSEPEAELEREAKKSA 413

Query: 417 LLRDQPRGRGQRGARQRRRTPRPLTSARAKAANVQEPEKKKK 458
                      R   Q+ +  RP    +AK   V+   K+ +
Sbjct: 414 KKPQSSSTEPARKPGQKEKRVRPEEKQQAKPVKVERTRKRSE 455


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 54/251 (21%), Positives = 94/251 (37%), Gaps = 21/251 (8%)

Query: 222 VEQAPLAIEDLLNELDTQDEEVASDSDESSEGGERGDALSQKRSEKPPAGSICRAEPEAG 281
           +EQ  LA   +  + + +D+    + + S E  ER  +  +++S  P      R+ P   
Sbjct: 136 IEQEKLA--SMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRR--RSSPVRR 191

Query: 282 EEQAGDDRD------SGGPVLQFDYEAVANRLFEMASRQSTPSQNRKRLYKVIRKLQDLA 335
           E +    R       S  P    + +     L E + +   PS         I K+    
Sbjct: 192 ERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPE 251

Query: 336 GGIFPEDEIPEKACRRLLEGRRQKKTKKQKRLLRLQQERGKGEKEPPSPGMERKRSRRRG 395
               P++  PEK  ++      ++K K + R     + R +     PS    R+R R R 
Sbjct: 252 PIPEPKEPSPEKNSKK-----EKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRS 306

Query: 396 VGADPEARAEAGEQPGTAERALLRDQP----RGRGQRGARQRRRTPRPL--TSARAKAAN 449
               P  R     +P    R   R  P      R +   R+RRR+   L  +S+ + ++ 
Sbjct: 307 RSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSR 366

Query: 450 VQEPEKKKKRR 460
            + P KK  +R
Sbjct: 367 SRSPPKKPPKR 377



 Score = 33.5 bits (75), Expect = 0.42
 Identities = 22/74 (29%), Positives = 30/74 (40%), Gaps = 1/74 (1%)

Query: 385 GMERKRSRRRGVGADPEARAEAGEQPGTAERALLRDQPRGRGQRGARQRRRTPRPLTSAR 444
           G    RS R      P  R     +P  A +      P  RG   + QRR++P P T   
Sbjct: 663 GSSPSRSTREARSPQPNKRHSPSPRP-RAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPI 721

Query: 445 AKAANVQEPEKKKK 458
            + +   EP+K KK
Sbjct: 722 RRVSRTPEPKKIKK 735


>gi|14249158 hepatoma-derived growth factor-related protein 2
           isoform 2 [Homo sapiens]
          Length = 670

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 68/294 (23%), Positives = 113/294 (38%), Gaps = 63/294 (21%)

Query: 203 RTKDSLVLNNITRGIFETIVEQAPLAIEDLLNELDTQDEEVASDSDESSEGGERGDALSQ 262
           ++ D+  L   T  +  ++ ++A  A  DL     +  EE  S+S   SE     D   +
Sbjct: 148 KSSDNSGLKRKTPALKMSVSKRARKASSDLDQASVSPSEEENSESSSESEKTSDQDFTPE 207

Query: 263 KRS------EKPPAGSICRAEPEAGEEQAGDDRDSGGPVLQFDYEAVANRLFEMASRQST 316
           K++        P  G   +  P A +  +  D D   P    +  A+A      +S  S+
Sbjct: 208 KKAAVRAPRRGPLGGRKKKKAPSASDSDSKADSDGAKP----EPVAMARSASSSSSSSSS 263

Query: 317 ---------PSQNRKRLYKVIRKLQDLAGGIFPEDEIP---------------------- 345
                    P + RK   K + K +    G  P+ E P                      
Sbjct: 264 SDSDVSVKKPPRGRKPAEKPLPKPR----GRKPKPERPPSSSSSDSDSDEVDRISEWKRR 319

Query: 346 EKACRRLLEGRRQKKTKKQKRLLRLQQERGKGEKEPPSPGMERKRSRRRGVGADPEARAE 405
           ++A RR LE RR+++ +++ R LR Q++  K          ER+R R     AD   R E
Sbjct: 320 DEARRRELEARRRREQEEELRRLREQEKEEK----------ERRRER-----AD---RGE 361

Query: 406 AGEQPGTAERALLRDQPRGRGQRGARQRRRTPRPLTSARAKAANVQEPEKKKKR 459
           A    G +    LR+      +RG + R R P   + +  +A   +E +K  K+
Sbjct: 362 AERGSGGSSGDELREDDEPVKKRGRKGRGRGPPSSSDSEPEAELEREAKKSAKK 415



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 50/222 (22%), Positives = 87/222 (39%), Gaps = 36/222 (16%)

Query: 244 ASDSDESSEGGERGDALSQKRSEKPPAGSICRAEPEAGEEQAGDDRDSGGPVLQFDYEAV 303
           +SDSD S +   RG   ++K   KP      + +PE     +  D DS            
Sbjct: 263 SSDSDVSVKKPPRGRKPAEKPLPKPRGR---KPKPERPPSSSSSDSDSDE---------- 309

Query: 304 ANRLFEMASRQSTPSQNRKRLYKVIRKLQDLAGGIFPEDEIPEKACRRLLEGRRQKKTKK 363
            +R+ E   R       R+R  +  R+ +             E+  RRL E  +++K ++
Sbjct: 310 VDRISEWKRRDEA----RRRELEARRRREQ------------EEELRRLREQEKEEKERR 353

Query: 364 QKRLLRLQQERGKGE------KEPPSPGMER-KRSRRRGVGADPEARAEAGEQPGTAERA 416
           ++R  R + ERG G       +E   P  +R ++ R RG  +  ++  EA  +    + A
Sbjct: 354 RERADRGEAERGSGGSSGDELREDDEPVKKRGRKGRGRGPPSSSDSEPEAELEREAKKSA 413

Query: 417 LLRDQPRGRGQRGARQRRRTPRPLTSARAKAANVQEPEKKKK 458
                      R   Q+ +  RP    +AK   V+   K+ +
Sbjct: 414 KKPQSSSTEPARKPGQKEKRVRPEEKQQAKPVKVERTRKRSE 455


>gi|122937227 U2-associated SR140 protein [Homo sapiens]
          Length = 1029

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 51/230 (22%), Positives = 88/230 (38%), Gaps = 16/230 (6%)

Query: 235  ELDTQDEEVASDSDESSEGGERGDALSQKRSEKPPAGSICRAEPEAGEEQAGDDRDSGGP 294
            E   Q+EE   + D  S   E     S    E+       +   E  EE+    R+    
Sbjct: 792  ENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYS-EMSEEKRAKLREIELK 850

Query: 295  VLQFDYEAVANRLFEMASRQSTPSQNRKRLYKVIRK--LQDLAGGIFPEDEIPEKACRRL 352
            V++F  E       E   R   P Q+ +   +  R   LQ         +   +K  +  
Sbjct: 851  VMKFQDE------LESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDKKDKEK 904

Query: 353  LEGRRQKKTKKQKRLLRLQQERGKGEKEPPSPGMERKRSRRRGVGADPEA----RAEAGE 408
            LE R + K +K +     ++ER +     PSP   R  S RR     P++    R+E   
Sbjct: 905  LESRSKDKKEKDE-CTPTRKERKRRHSTSPSPS--RSSSGRRVKSPSPKSERSERSERSH 961

Query: 409  QPGTAERALLRDQPRGRGQRGARQRRRTPRPLTSARAKAANVQEPEKKKK 458
            +  +  R+  +D PR   ++  R    +  P  S R+++ + ++  KK +
Sbjct: 962  KESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSRRSRSRSPKKSGKKSR 1011


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 39.7 bits (91), Expect = 0.006
 Identities = 46/237 (19%), Positives = 96/237 (40%), Gaps = 19/237 (8%)

Query: 235  ELDTQDEEVASDSDESSEGGERGDALSQKRSEKPPAGSICRAEPEAGEEQAGDDRDSGGP 294
            +L  ++E++  +  E     ER     + +  +     +   EPE    Q  + +     
Sbjct: 935  QLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEE 994

Query: 295  VLQFDYEAVANRLFEMASRQSTPSQNRK------------RLYKVIRKLQDLAGGIFPED 342
             LQ + E +     E   RQ    Q RK            R  +  R+LQ+       E+
Sbjct: 995  ELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEE 1054

Query: 343  EIPEKACRRLLEGRRQKKTKKQKRLLRLQQERGKGEKEPPSPGMERKRSRRRGVGADPEA 402
            E+ ++  + L E R  ++ ++ +R  R ++E  + E++      E++R + R      E 
Sbjct: 1055 ELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQER------ER 1108

Query: 403  RAEAGEQPGTAERALLRDQPRGRGQRGARQRRRTPRPLTSARAKAANVQEPEKKKKR 459
            +    E+    E  LLR++   R ++   ++ R    +     +    +EPEK++++
Sbjct: 1109 QCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLR-EEPEKRRRQ 1164



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 60/240 (25%), Positives = 99/240 (41%), Gaps = 18/240 (7%)

Query: 230 EDLLNELDTQ--DEEVASDSDESSEGGERGDALSQKRSEKPPAGSICRAEPEAGEEQAGD 287
           ++ L + D Q  DEE+     E  E  ER     Q +S K         E +    +  +
Sbjct: 158 QERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLE 217

Query: 288 DRDSGGPVLQFDYEAVANRLFEMASRQSTPSQNRKR---LYKVIRKLQD----LAGGIFP 340
            R  G    Q       +R+F+    +    + RKR   L K   KLQ+        +  
Sbjct: 218 LRRKGREEKQQQRRERQDRVFQ----EEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQE 273

Query: 341 EDEIPEKACRRLLEGRRQKKTKKQKRLLRLQQERGKGEKEPPSPGMERKRSRRRGVGADP 400
           E+E   K  R+ L   RQ++ ++Q+RL R QQ R K E+E      ER+  + R      
Sbjct: 274 EEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQER-----R 328

Query: 401 EARAEAGEQPGTAERALLRDQPRGRGQRGARQRRRTPRPLTSARAKAANVQEPEKKKKRR 460
           E + E  EQ    E+   R+Q   R Q   R+ ++  R     R +    +E + +++++
Sbjct: 329 EQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQ 388



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 49/229 (21%), Positives = 92/229 (40%), Gaps = 28/229 (12%)

Query: 239 QDEEVASDSDESSEGGERGDALSQKRSEKPPAGSICRAEPEAGEEQAGDDRDSGGPVLQF 298
           Q+EE     +E  E  ER +   ++R ++       R E +   EQ  + R+        
Sbjct: 310 QEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERRE-------- 361

Query: 299 DYEAVANRLFEMASRQSTPSQNRKRLYKVIRKLQDLAGGIFPEDEIPEKACRRLLEGRRQ 358
             + +     E    Q    + + R  + +R+ Q L           E+  RR  + RR+
Sbjct: 362 --QQLRREQEEERREQQLRREQQLRREQQLRREQQLRR---------EQQLRREQQLRRE 410

Query: 359 KKTKKQKRLLRLQQERGKGEKEPPSPGMERKRSRRRGVGADPEAR--------AEAGEQP 410
           ++ +++++L R QQ R + E+E      E++R  +R      E R         E  EQ 
Sbjct: 411 QQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQE 470

Query: 411 GTAERALLRDQPRGRGQRGARQRRRTPRPLTSARAKAANVQEPEKKKKR 459
              ++ L RDQ   R +R  +      R     R +    ++ E++++R
Sbjct: 471 -RRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQR 518



 Score = 34.7 bits (78), Expect = 0.19
 Identities = 32/126 (25%), Positives = 61/126 (48%), Gaps = 5/126 (3%)

Query: 341 EDEIPEKACRRLLEGRRQKKTKKQKRLLRLQQERGKGEKEPPSPGMERKRSRRRG--VGA 398
           E+E  E+  RR  + RR+++ ++++RL R ++E    ++      + R++  RR   +  
Sbjct: 493 EEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKR 552

Query: 399 DPEAR--AEAGEQPGTAERALLRDQPRGRGQRGARQR-RRTPRPLTSARAKAANVQEPEK 455
           + E R   E  EQ    E+   RDQ   R +   +QR +R        R K   V+  E+
Sbjct: 553 EEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQ 612

Query: 456 KKKRRE 461
           +++R +
Sbjct: 613 EERREQ 618



 Score = 34.7 bits (78), Expect = 0.19
 Identities = 58/236 (24%), Positives = 101/236 (42%), Gaps = 25/236 (10%)

Query: 235 ELDTQDEEVASDSDESSEGGERGDALSQKRSEKPPAGSICRAEPEAGEEQAGDDRDSG-G 293
           E +   + + S+     E  ER + L ++  EK       R E E  E++   +++    
Sbjct: 524 EEERLQQRLRSEQQLRREQEERREQLLKREEEK-------RLEQERREQRLKREQEERRD 576

Query: 294 PVLQFDYEAVANRLF---EMASRQSTPSQNRKRLYKVIRKLQDLAGGIFPEDEIPEKACR 350
            +L+ + E    RL    E    Q    +  +RL +  R+ Q L      + E PE+  R
Sbjct: 577 QLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRL------KREEPEEERR 630

Query: 351 RLLEGRRQKKTKKQKRLLRLQQERGKG--EKEPPSPGMERKRSRRRGVGADPEARAEAGE 408
           + L    +++ ++Q++L R QQER +   ++E     +E++  R        +  AE  E
Sbjct: 631 QQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEE-E 689

Query: 409 QPGTAERALLRD---QPRGRGQRGARQRRRTPRPLTSARAKAANVQEPEKKKKRRE 461
           Q    ER   R    Q +   +  ARQ +   RP      +    QE E+K++RRE
Sbjct: 690 QEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRR--QEQEEKRRRRE 743



 Score = 32.7 bits (73), Expect = 0.71
 Identities = 48/220 (21%), Positives = 94/220 (42%), Gaps = 22/220 (10%)

Query: 248 DESSEGGERGDALSQKRSEKP--PAGSICRAEPEAGEEQAGDDRDSGGPVLQFDYEAVAN 305
           ++  +  ER D + Q+  EK      ++ R E    EE+  ++       LQ + E +  
Sbjct: 225 EKQQQRRERQDRVFQEEEEKEWRKRETVLRKE----EEKLQEEEPQRQRELQEEEEQLRK 280

Query: 306 ---RLFEMASRQSTPSQNRKRLYKVIRKLQDLAGGIFPEDEIPEKACRRLLEGRRQKKTK 362
              +      ++    Q R R  + +R+ Q+       E+   ++  RR  + RR+++ +
Sbjct: 281 LERQELRRERQEEEQQQQRLRREQQLRRKQE-------EERREQQEERREQQERREQQEE 333

Query: 363 KQKRLLRLQQERGKGEKEPPSPGMERKRSRRRGVGADPEARAEAGEQPGTAERALLRDQP 422
           ++++ LR +QE  + ++       ER+  + R      E   E  EQ    E+ L R+Q 
Sbjct: 334 RREQQLRREQEERREQQLRREQEEERREQQLR-----REQEEERREQQLRREQQLRREQQ 388

Query: 423 RGRGQRGAR-QRRRTPRPLTSARAKAANVQEPEKKKKRRE 461
             R Q+  R Q+ R  + L   +      Q   +++ RRE
Sbjct: 389 LRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 428



 Score = 31.6 bits (70), Expect = 1.6
 Identities = 28/123 (22%), Positives = 56/123 (45%), Gaps = 7/123 (5%)

Query: 346 EKACRRLLEGRRQKKTK------KQKRLLRLQQERGKGEKEPPSPGMERKRSRRRGVGAD 399
           E+   R  + RR+++ K      +++R L+L++E  + ++E     + R++  RR     
Sbjct: 461 EEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLK 520

Query: 400 PEARAEAGEQPGTAERALLRDQPRGRGQRGAR-QRRRTPRPLTSARAKAANVQEPEKKKK 458
            +   E  +Q   +E+ L R+Q   R Q   R + +R  +     R K    +  ++  K
Sbjct: 521 RQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLK 580

Query: 459 RRE 461
           R E
Sbjct: 581 REE 583



 Score = 31.6 bits (70), Expect = 1.6
 Identities = 48/242 (19%), Positives = 91/242 (37%), Gaps = 15/242 (6%)

Query: 235  ELDTQDEEVASDSDESSEGGERGDALSQKRSEKPPAGSICRAEPEAGEEQAGDDRDSGGP 294
            EL  ++E++  +  E     E      ++   +     + R EPE    Q  + +     
Sbjct: 1115 ELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEE 1174

Query: 295  VLQFDYEAVAN---------RLFEMASRQSTPSQNRKRLYKVIRKLQDLAGGIFPEDEIP 345
             LQ + E +           R  +    +    Q RK+ Y+   +  DL     PE E  
Sbjct: 1175 ELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENA 1234

Query: 346  EKACRRLLEGRRQKKTKK----QKRLLRLQQERGK--GEKEPPSPGMERKRSRRRGVGAD 399
             +  +   +GR  ++ ++    Q R  + QQ+     GE++      ER+R ++R     
Sbjct: 1235 VRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFP 1294

Query: 400  PEARAEAGEQPGTAERALLRDQPRGRGQRGARQRRRTPRPLTSARAKAANVQEPEKKKKR 459
             E + E  EQ     R     + +   +    ++RR        R +   +QE E++  R
Sbjct: 1295 EEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLR 1354

Query: 460  RE 461
            R+
Sbjct: 1355 RQ 1356



 Score = 29.3 bits (64), Expect = 7.9
 Identities = 38/176 (21%), Positives = 67/176 (38%), Gaps = 6/176 (3%)

Query: 219 ETIVEQAPLAIEDLLNELDTQDEEVASDSDESSEGGERGDALSQKRSEKPPAGSICRAEP 278
           E I  + P     L +E D +  +V S      EG  R     +KR  +     +   E 
Sbjct: 695 ERIKSRIPKWQWQLESEADARQSKVYS-RPRKQEGQRRRQEQEEKRRRRE--SELQWQEE 751

Query: 279 EAGEEQAGDDRDSGGPVLQFDYEAVANRLFEMASRQSTPSQNRKRLYKVIRKLQDLAGGI 338
           E    Q  ++        Q+  E  + R  +  S +    + R+R  +   + Q      
Sbjct: 752 ERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEER-QQREQRF 810

Query: 339 FPEDEIPEKACRRLLEGRRQKKTKKQKRLLRLQQERGKGEKEPPSPGMERKRSRRR 394
            PE+E  EK  RR     R+K+ +  +   +LQ+     + +    G++  + RRR
Sbjct: 811 LPEEE--EKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRR 864


>gi|24475863 H1 histone family, member O, oocyte-specific [Homo
           sapiens]
          Length = 346

 Score = 39.7 bits (91), Expect = 0.006
 Identities = 62/247 (25%), Positives = 99/247 (40%), Gaps = 46/247 (18%)

Query: 253 GGERGDALSQKRSEKPPAGSICRAEPEAGEEQAGDDRDSGGPVLQFDYEAVANRLFEMAS 312
           GG    +L   R   P    +  A  +AGE++ G    +    +   Y  V    F+   
Sbjct: 39  GGPSHSSLPVGRRHPPVLRMVLEAL-QAGEQRRGTSVAAIKLYILHKYPTVDVLRFKYLL 97

Query: 313 RQSTPSQNRKRLYKVIRKLQDLAGG--------------IFPEDEIPEKACRRLLE--GR 356
           +Q+  +  R+ L  + R L   A G              I P    P  A RR  E  G+
Sbjct: 98  KQALATGMRRGL--LARPLNSKARGATGSFKLVPKHKKKIQPRKMAPATAPRRAGEAKGK 155

Query: 357 RQKKTKKQK-------RLLRLQQERGKGEKEPPSPGMERKRSRRRGVGADPEARAEAGE- 408
             KK  + K       ++ +  +   K +K PP PG   +++R++G GA  + RA++GE 
Sbjct: 156 GPKKPSEAKEDPPNVGKVKKAAKRPAKVQKPPPKPGAATEKARKQG-GAAKDTRAQSGEA 214

Query: 409 -----QPGTAERAL-----LRDQPRGRGQRG----ARQRRRTPRPLTSARAKAANVQ--- 451
                +P  A RA      L  + + +G R     A   R+T     S++  A+ V+   
Sbjct: 215 RKVPPKPDKAMRAPSSAGGLSRKAKAKGSRSSQGDAEAYRKTKAESKSSKPTASKVKNGA 274

Query: 452 -EPEKKK 457
             P KKK
Sbjct: 275 ASPTKKK 281


>gi|29568103 U1 small nuclear ribonucleoprotein 70 kDa [Homo
           sapiens]
          Length = 437

 Score = 39.3 bits (90), Expect = 0.008
 Identities = 40/164 (24%), Positives = 63/164 (38%), Gaps = 32/164 (19%)

Query: 287 DDRDSGGPVLQFDYEAVANRLFEMASRQSTPSQNRKRLYKVIRKLQDLAGGIFPEDEIPE 346
           D+R    P+   D +    R     SR+    + R+R     R+ +  +          +
Sbjct: 220 DERPGPSPLPHRDRDRDRERERRERSRERDKERERRRSRSRDRRRRSRSR---------D 270

Query: 347 KACRRLLEGRRQKKTKKQKRLLRLQQERGKGEKEPPSPGMERKRSRRRGVGADPEARAEA 406
           K  RR    R + K + +KR     +ER + E+E        ++   RG G D    +EA
Sbjct: 271 KEERRRSRERSKDKDRDRKRRSSRSRERARRERE--------RKEELRGGGGDMAEPSEA 322

Query: 407 GEQP---------------GTAERALLRDQPRGRGQRGARQRRR 435
           G+ P               G  E+   RD+ R R  R  R+RRR
Sbjct: 323 GDAPPDDGPPGELGPDGPDGPEEKGRDRDRERRRSHRSERERRR 366


>gi|52426743 cisplatin resistance-associated overexpressed protein
           [Homo sapiens]
          Length = 432

 Score = 39.3 bits (90), Expect = 0.008
 Identities = 36/128 (28%), Positives = 57/128 (44%), Gaps = 14/128 (10%)

Query: 342 DEIPEKACRRLLEGRRQKKTKKQKRLLRLQQERGKGEKEPPSPGMERKRSRRRGV----- 396
           +E+ EK  +R  E  R ++ KK+K      QER + EKE      ER+R RRR       
Sbjct: 228 EELKEKLRKRTEEPDRDERLKKEK------QEREEREKEREREREERERKRRREEEEREK 281

Query: 397 --GADPEARAEAGEQPGTAERALLRDQPRGRGQRGARQR-RRTPRPLTSARAKAANVQEP 453
               D E R  +  +   + R   R   R R  + +R R RR  R     R+++ +  E 
Sbjct: 282 ERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSER 341

Query: 454 EKKKKRRE 461
           + + + R+
Sbjct: 342 KHRSRSRD 349


>gi|19923485 cisplatin resistance-associated overexpressed protein
           [Homo sapiens]
          Length = 432

 Score = 39.3 bits (90), Expect = 0.008
 Identities = 36/128 (28%), Positives = 57/128 (44%), Gaps = 14/128 (10%)

Query: 342 DEIPEKACRRLLEGRRQKKTKKQKRLLRLQQERGKGEKEPPSPGMERKRSRRRGV----- 396
           +E+ EK  +R  E  R ++ KK+K      QER + EKE      ER+R RRR       
Sbjct: 228 EELKEKLRKRTEEPDRDERLKKEK------QEREEREKEREREREERERKRRREEEEREK 281

Query: 397 --GADPEARAEAGEQPGTAERALLRDQPRGRGQRGARQR-RRTPRPLTSARAKAANVQEP 453
               D E R  +  +   + R   R   R R  + +R R RR  R     R+++ +  E 
Sbjct: 282 ERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSER 341

Query: 454 EKKKKRRE 461
           + + + R+
Sbjct: 342 KHRSRSRD 349


>gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 202

 Score = 38.9 bits (89), Expect = 0.010
 Identities = 28/117 (23%), Positives = 58/117 (49%), Gaps = 4/117 (3%)

Query: 346 EKACRRLLEGRRQKKTKKQKRLLRLQQERGKGEKEPPSPGMERKRSRRRGVGADPEARAE 405
           E+  +R  E   +++T++Q+   R ++ + + ++E      +R R R+R    + E   +
Sbjct: 61  ERDRQRQRERETERETERQRERQRQRERKRQTDRERDK---DRDRERKRETDRNRERNRK 117

Query: 406 AG-EQPGTAERALLRDQPRGRGQRGARQRRRTPRPLTSARAKAANVQEPEKKKKRRE 461
            G E+    ER   R++ R R +   RQR+R  +  T    +    +E  KK++++E
Sbjct: 118 GGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKE 174



 Score = 35.4 bits (80), Expect = 0.11
 Identities = 32/121 (26%), Positives = 52/121 (42%), Gaps = 17/121 (14%)

Query: 346 EKACRRLLEGRRQKKTKKQKRLLRLQQERGKGEKEPPSPGMERKRSRRRGVGADPEARAE 405
           E+   R  E +RQ++ K+Q       +ER K          +R R R R  G + + + E
Sbjct: 73  ERETERQRERQRQRERKRQT-----DRERDKDRDRERKRETDRNRERNRKGGRERDKQTE 127

Query: 406 AGEQPGTAERALLRDQPRGRGQRGARQRRR-----TPRPLTSARAKAANVQEPEKKKKRR 460
                   ER   R++ R R +   RQR R       R   + R +    ++ E+KK+R+
Sbjct: 128 R-------ERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERK 180

Query: 461 E 461
           E
Sbjct: 181 E 181


>gi|14790190 spen homolog, transcriptional regulator [Homo sapiens]
          Length = 3664

 Score = 38.9 bits (89), Expect = 0.010
 Identities = 51/222 (22%), Positives = 90/222 (40%), Gaps = 26/222 (11%)

Query: 251  SEGGERGDALSQKRSEKPPAGSICRAEPEAGE--EQAGDDRDSGGPVLQFDYEAVA-NRL 307
            S+  ++ +  ++ ++EKP A +   AEP+A +  E A + +      L+ D    A ++ 
Sbjct: 1760 SKPAQKSEEANEPKAEKPDATA--DAEPDANQKAEAAPESQPPASEDLEVDPPVAAKDKK 1817

Query: 308  FEMASRQSTPSQNRKRLY---KVIRKLQDLAGGIFPEDEIPEKACRRLLEGRRQKKTKKQ 364
               + R  TP Q          V RK + +          P    ++LLE + + +    
Sbjct: 1818 PNKSKRSKTPVQAAAVSIVEKPVTRKSERIDREKLKRSNSPRGEAQKLLELKMEAE---- 1873

Query: 365  KRLLRLQQERGKGEKEPPSPGMERKRSRRRGVGA------DPEARA---EAGEQPGTAER 415
             ++ R   +    + E P P +   R+RRR V +      D E R+   E  EQP    +
Sbjct: 1874 -KITRTASKNSAADLEHPEPSLPLSRTRRRNVRSVYATMGDHENRSPVKEPVEQPRVTRK 1932

Query: 416  ALLRDQPRGRGQRGARQRRRTPRPLTSARAKAANVQEPEKKK 457
             L R+           +R R P+     R +A   +E E K+
Sbjct: 1933 RLERELQEAAAVPTTPRRGRPPK----TRRRADEEEENEAKE 1970


>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
          Length = 2003

 Score = 38.5 bits (88), Expect = 0.013
 Identities = 59/234 (25%), Positives = 99/234 (42%), Gaps = 12/234 (5%)

Query: 219  ETIVEQAPLAIEDLLNELDTQDEEV-ASDSDESSEGGERGDALSQKRSEKPPAGSICRAE 277
            E +VEQ   A E+L  +L  ++EE+ A+ +    EGG R   L   R  +    ++  A+
Sbjct: 1094 EQMVEQQQRA-EELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQ---AALAEAQ 1149

Query: 278  PEAGEEQAGDDR-DSGGPVLQFDYEAVANRLFEMASRQSTPSQNRKRLYKVIRKLQDLAG 336
             +   E+    + +     L  + EA+   L +  +  ST +Q   R  K  +++ +L  
Sbjct: 1150 EDLESERVARTKAEKQRRDLGEELEALRGELED--TLDSTNAQQELRS-KREQEVTELKK 1206

Query: 337  GIFPEDEIPEKACRRLLEGRRQKKTKKQKRLLRLQQERGKGEKEPPSPGMERKRSRRRGV 396
             +  E  I E A + L +   Q   +  ++L   Q  RGKG  E     +E + S  R  
Sbjct: 1207 TLEEETRIHEAAVQELRQRHGQALGELAEQLE--QARRGKGAWEKTRLALEAEVSELRAE 1264

Query: 397  GADPEARAEAGEQPGTAERALLRDQPRGRGQRGARQRRRTPRPLTSARAKAANV 450
             +  +   + GEQ       L   + +GR   G R R      L  A+A+  NV
Sbjct: 1265 LSSLQTARQEGEQ-RRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENV 1317


>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
          Length = 1995

 Score = 38.5 bits (88), Expect = 0.013
 Identities = 59/234 (25%), Positives = 99/234 (42%), Gaps = 12/234 (5%)

Query: 219  ETIVEQAPLAIEDLLNELDTQDEEV-ASDSDESSEGGERGDALSQKRSEKPPAGSICRAE 277
            E +VEQ   A E+L  +L  ++EE+ A+ +    EGG R   L   R  +    ++  A+
Sbjct: 1086 EQMVEQQQRA-EELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQ---AALAEAQ 1141

Query: 278  PEAGEEQAGDDR-DSGGPVLQFDYEAVANRLFEMASRQSTPSQNRKRLYKVIRKLQDLAG 336
             +   E+    + +     L  + EA+   L +  +  ST +Q   R  K  +++ +L  
Sbjct: 1142 EDLESERVARTKAEKQRRDLGEELEALRGELED--TLDSTNAQQELRS-KREQEVTELKK 1198

Query: 337  GIFPEDEIPEKACRRLLEGRRQKKTKKQKRLLRLQQERGKGEKEPPSPGMERKRSRRRGV 396
             +  E  I E A + L +   Q   +  ++L   Q  RGKG  E     +E + S  R  
Sbjct: 1199 TLEEETRIHEAAVQELRQRHGQALGELAEQLE--QARRGKGAWEKTRLALEAEVSELRAE 1256

Query: 397  GADPEARAEAGEQPGTAERALLRDQPRGRGQRGARQRRRTPRPLTSARAKAANV 450
             +  +   + GEQ       L   + +GR   G R R      L  A+A+  NV
Sbjct: 1257 LSSLQTARQEGEQ-RRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENV 1309


>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
          Length = 2036

 Score = 38.5 bits (88), Expect = 0.013
 Identities = 59/234 (25%), Positives = 99/234 (42%), Gaps = 12/234 (5%)

Query: 219  ETIVEQAPLAIEDLLNELDTQDEEV-ASDSDESSEGGERGDALSQKRSEKPPAGSICRAE 277
            E +VEQ   A E+L  +L  ++EE+ A+ +    EGG R   L   R  +    ++  A+
Sbjct: 1127 EQMVEQQQRA-EELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQ---AALAEAQ 1182

Query: 278  PEAGEEQAGDDR-DSGGPVLQFDYEAVANRLFEMASRQSTPSQNRKRLYKVIRKLQDLAG 336
             +   E+    + +     L  + EA+   L +  +  ST +Q   R  K  +++ +L  
Sbjct: 1183 EDLESERVARTKAEKQRRDLGEELEALRGELED--TLDSTNAQQELRS-KREQEVTELKK 1239

Query: 337  GIFPEDEIPEKACRRLLEGRRQKKTKKQKRLLRLQQERGKGEKEPPSPGMERKRSRRRGV 396
             +  E  I E A + L +   Q   +  ++L   Q  RGKG  E     +E + S  R  
Sbjct: 1240 TLEEETRIHEAAVQELRQRHGQALGELAEQLE--QARRGKGAWEKTRLALEAEVSELRAE 1297

Query: 397  GADPEARAEAGEQPGTAERALLRDQPRGRGQRGARQRRRTPRPLTSARAKAANV 450
             +  +   + GEQ       L   + +GR   G R R      L  A+A+  NV
Sbjct: 1298 LSSLQTARQEGEQ-RRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENV 1350


>gi|122114651 ubiquitin specific peptidase 36 [Homo sapiens]
          Length = 1123

 Score = 38.5 bits (88), Expect = 0.013
 Identities = 56/257 (21%), Positives = 97/257 (37%), Gaps = 27/257 (10%)

Query: 226 PLAIEDLLNELDTQDEEVASD-----SDESSEGGERGDALSQKRSEKPPAGSICRAEPEA 280
           P    DL + + T    VAS      +   S   +    L    S  P   S     P  
Sbjct: 712 PSPSSDLTHPMKTSHPVVASTWPVHRARAVSPAPQSSSRLQPPFSPHPTLLSSTPKPPGT 771

Query: 281 GEEQAGDDRDSGGPVLQFDYEAVANRLFEMASRQSTPSQNRKRLYKVIRKLQDLAGGIFP 340
            E ++     +  P +  D  ++ ++L E +    +PS+ RK+ +  + + Q L      
Sbjct: 772 SEPRSCSSISTALPQVNEDLVSLPHQLPEASEPPQSPSEKRKKTF--VGEPQRLGSETRL 829

Query: 341 EDEIPEKACRRLLEGRRQKKTKKQKRLLRLQQERGKGEKEPPSPGMERKRS------RRR 394
              I E       + +R+KK + +       QE G+ +++P SP   R+        RR+
Sbjct: 830 PQHIREATAAPHGKRKRKKKKRPEDTAASALQE-GQTQRQPGSPMYRREGQAQLPAVRRQ 888

Query: 395 GVGADPEARAEAGEQPG-------TAERALLRDQPRGRGQRGARQR---RRTPRPLTSAR 444
             G  P+     G+Q G        + R   R    G G+ G   +   R +  P+    
Sbjct: 889 EDGTQPQVN---GQQVGCVTDGHHASSRKRRRKGAEGLGEEGGLHQDPLRHSCSPMGDGD 945

Query: 445 AKAANVQEPEKKKKRRE 461
            +A      +KKKK+R+
Sbjct: 946 PEAMEESPRKKKKKKRK 962


>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
          Length = 793

 Score = 38.5 bits (88), Expect = 0.013
 Identities = 61/287 (21%), Positives = 113/287 (39%), Gaps = 18/287 (6%)

Query: 175 EELTKVGAEELTADQNLKFIDPFCRIAARTKDSLVLNNITRGIFETIVEQAPLAIEDLLN 234
           E  T     ++  D    F++   R   R +  L      +  F+  +  A L++     
Sbjct: 78  EAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRM 137

Query: 235 ELDTQDEEVASDSDESSEGGERGDALSQKRSEKPPAGSICR-AEPEAGEEQAGDDRDSGG 293
           + DT + E     ++S    ER +    +   K    +  R AE    E++  ++ +   
Sbjct: 138 QNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEK 197

Query: 294 PVLQFDYEAVANRLFEMASRQSTPSQNRKRLYKVIRKLQDLAGGIFPEDEIPEKACRRLL 353
           P      E   N++  M   ++T SQ       V+  L++  G I  E+   E+   +  
Sbjct: 198 PKRGSIGE---NQVEVMVEEKTTESQEET----VVMSLKN--GQISSEEPKQEEEREQGS 248

Query: 354 EGRRQKKTKKQKRLLRLQQERGKGEKEPPSPGMERKRSRRRGVGADPEARAEAGEQPGTA 413
           +     +  +++   R + ER + E E      ER ++ +    AD  AR EA E+    
Sbjct: 249 DEISHHEKMEEEDKERAEAERARLEAEE----RERIKAEQDKKIADERARIEAEEKAAAQ 304

Query: 414 ER----ALLRDQPRGRGQRGARQRRRTPRPLTSARAKAANVQEPEKK 456
           ER    A  R++ R   +R A +R+R       A  +   ++E EK+
Sbjct: 305 ERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKR 351



 Score = 29.3 bits (64), Expect = 7.9
 Identities = 26/108 (24%), Positives = 46/108 (42%), Gaps = 10/108 (9%)

Query: 358 QKKTKKQKRLLRLQQERGKGEKEPPSPGMERKRSRRRGVGADP----EARAEAGEQPGTA 413
           +K T+ Q+  + +  + G+   E P    ER++      G+D     E   E  ++   A
Sbjct: 214 EKTTESQEETVVMSLKNGQISSEEPKQEEEREQ------GSDEISHHEKMEEEDKERAEA 267

Query: 414 ERALLRDQPRGRGQRGARQRRRTPRPLTSARAKAANVQEPEKKKKRRE 461
           ERA L  + R R +    ++    R    A  KAA  +   ++ + RE
Sbjct: 268 ERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERE 315


>gi|84043963 eukaryotic translation initiation factor 5B [Homo
           sapiens]
          Length = 1220

 Score = 38.1 bits (87), Expect = 0.017
 Identities = 47/253 (18%), Positives = 103/253 (40%), Gaps = 23/253 (9%)

Query: 230 EDLLNELDTQDEEVASDSDESSEGGERGDALSQKRSEKPPAGSICRAEPEAGE------E 283
           +D  N+L  + +  A  S++  +G E  +  S+K  E+    S   +  E+ E       
Sbjct: 140 DDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKG 199

Query: 284 QAGDDRDSGGPVLQ---------FDYEAVANRLFEMASRQSTPSQNRKRLYKVIRKLQDL 334
           Q  + ++  GP ++         F  + VA +  E   R+       K   + +++ ++L
Sbjct: 200 QKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEEL 259

Query: 335 AGGIFPEDEIPEKACRRLLEGRRQK-KTKKQKRLLRLQQERGK--GEKEPPSPGMERKRS 391
             G   +D+  +K  +R  E    K K      ++   +E+ +     E  + G ++K+ 
Sbjct: 260 ETG--KKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKD 317

Query: 392 RRRGVGADPEARAEAGEQPGTAERALLRD---QPRGRGQRGARQRRRTPRPLTSARAKAA 448
           +++  G   E   E  + P  A    +++   + +   +R  R+     + L    AK  
Sbjct: 318 KKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRK 377

Query: 449 NVQEPEKKKKRRE 461
             +  E++K+ R+
Sbjct: 378 EEERLEQEKRERK 390


>gi|239758013 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 819

 Score = 37.4 bits (85), Expect = 0.029
 Identities = 51/229 (22%), Positives = 86/229 (37%), Gaps = 21/229 (9%)

Query: 244 ASDSDESSEGGERGDA---LSQKRSEKPPAGSICRAEPEAGEEQAGDDRDSGGPVLQFDY 300
           A+   +S  G  RG     L ++      AG+  R    AGE+ A   R   GP      
Sbjct: 255 AATGGKSRVGKSRGGGDKKLRRQGQNAALAGAKRRGAATAGEKPAAKGRGGRGP------ 308

Query: 301 EAVANRLFEMASRQSTPSQNRKRLYKVIRKLQDLAGGIFPEDEIPEKACRRLLEGRRQKK 360
           +++  +          P +  ++  K         GG   +  +     R+  + RR KK
Sbjct: 309 KSLGGQNPRWGRGGKKPRRRGQKATKAAAAGTKRGGGGQQKAAVVGVKSRKK-QRRRGKK 367

Query: 361 TKKQKRLLRLQQERGKGEKEPPSPGMERKRSRRRGVGADPEARAEAGEQPGTAERALLRD 420
            ++QK      + RG G+K+       R   R++    +P  RA+  + P    R     
Sbjct: 368 PRRQKASAAGAKSRGGGDKKGLREAKRRGDGRKKPRWQNPRRRAQ--KAPAAKPRGGGSK 425

Query: 421 QPRGRGQRGARQR---------RRTPRPLTSARAKAANVQEPEKKKKRR 460
           +PR RG + A+ R         ++  R    AR KAA      +  K++
Sbjct: 426 KPRRRGPKAAKSRGGKSRSGGGKKPRRRGQKARQKAAEAGAESRGDKKQ 474



 Score = 33.9 bits (76), Expect = 0.32
 Identities = 53/233 (22%), Positives = 89/233 (38%), Gaps = 26/233 (11%)

Query: 241 EEVASDSDESSEGGERGDALSQKRS---EKPPAGSICRAEPEAGEEQAGDDRDSGGPVLQ 297
           +  A+ S     G ++  A +  +S   EKP   +   A+  +G++       S G    
Sbjct: 144 KSAAAGSKNRGAGAQKAAAAAGVKSQGGEKPQKAAAAGAKSRSGKKPRRRGAKSRGD--- 200

Query: 298 FDYEAVANRLFEMASRQSTPSQNRKRLYKVIRKLQDLAGGIFPEDEIPEKACRRLLEGRR 357
              E    R  E  SR       R++ +   R+ +  AGG        +K  ++   G++
Sbjct: 201 ---EDKKGRQREAKSRFGKTRGGRRKKH---RRPKPAAGGAKSRRGGGKKPQKQRRRGQK 254

Query: 358 QKKTKKQKRLLRLQQERGKGEKEPPSPGMERKRS--RRRGV---GADPEARAEAGEQPGT 412
                K     R+ + RG G+K+    G     +  +RRG    G  P A+   G  P +
Sbjct: 255 AATGGKS----RVGKSRGGGDKKLRRQGQNAALAGAKRRGAATAGEKPAAKGRGGRGPKS 310

Query: 413 AERALLR-----DQPRGRGQRGARQRRRTPRPLTSARAKAANVQEPEKKKKRR 460
                 R      +PR RGQ+  +      +     + KAA V    +KK+RR
Sbjct: 311 LGGQNPRWGRGGKKPRRRGQKATKAAAAGTKRGGGGQQKAAVVGVKSRKKQRR 363



 Score = 33.9 bits (76), Expect = 0.32
 Identities = 32/124 (25%), Positives = 53/124 (42%), Gaps = 26/124 (20%)

Query: 346 EKACRRLLEGRRQKKTKKQKRLLRLQQERGKGEKEPPSPGMERKRSRRRGVGADPEARAE 405
           EK  +    G + +  KK +R         +G K   S G E K+ R+R      EA++ 
Sbjct: 172 EKPQKAAAAGAKSRSGKKPRR---------RGAK---SRGDEDKKGRQR------EAKSR 213

Query: 406 AGEQPGTAERALLRDQP--------RGRGQRGARQRRRTPRPLTSARAKAANVQEPEKKK 457
            G+  G   +   R +P        RG G++  +QRRR  +  T  +++    +    KK
Sbjct: 214 FGKTRGGRRKKHRRPKPAAGGAKSRRGGGKKPQKQRRRGQKAATGGKSRVGKSRGGGDKK 273

Query: 458 KRRE 461
            RR+
Sbjct: 274 LRRQ 277



 Score = 31.6 bits (70), Expect = 1.6
 Identities = 25/88 (28%), Positives = 39/88 (44%), Gaps = 5/88 (5%)

Query: 355 GRRQKKTKKQKRLLRLQQERGKGEKEPPSPGMERKRSRRRGVGADPEARAEAGEQP---- 410
           G   KK ++QK     ++ R +G+K   + G E ++  ++  GA        GEQ     
Sbjct: 53  GSGDKKLRRQKAAAGGKKARLRGQKGAVA-GKEARQHWQKAAGAGGAENRGGGEQKAAAA 111

Query: 411 GTAERALLRDQPRGRGQRGARQRRRTPR 438
           GT        +PR RGQ+ A    + PR
Sbjct: 112 GTKSLGGRGRKPRRRGQKAAATGSKKPR 139


>gi|4826894 phosphodiesterase 1C [Homo sapiens]
          Length = 634

 Score = 37.4 bits (85), Expect = 0.029
 Identities = 28/88 (31%), Positives = 44/88 (50%), Gaps = 5/88 (5%)

Query: 223 EQAPLAIEDLLNELD--TQDEEVASDSDESSEGGERGDALSQKRSEKP--PAGSICRAEP 278
           E+A LA E+   E++  +Q EE AS   E    GE  + ++  R+ K   P G   +AE 
Sbjct: 537 EKARLAAEEQQKEMEAKSQAEEGASGKAEKKTSGETKNQVNGTRANKSDNPRGKNSKAEK 596

Query: 279 EAGEEQA-GDDRDSGGPVLQFDYEAVAN 305
            +GE+Q  GD +D      + D+  + N
Sbjct: 597 SSGEQQQNGDFKDGKNKTDKKDHSNIGN 624


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.133    0.377 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,042,815
Number of Sequences: 37866
Number of extensions: 876522
Number of successful extensions: 7014
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 61
Number of HSP's successfully gapped in prelim test: 337
Number of HSP's that attempted gapping in prelim test: 5815
Number of HSP's gapped (non-prelim): 1163
length of query: 461
length of database: 18,247,518
effective HSP length: 106
effective length of query: 355
effective length of database: 14,233,722
effective search space: 5052971310
effective search space used: 5052971310
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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