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Search of human proteins with 4503129
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4503129 catenin, alpha-like 1 [Homo sapiens]
(734 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4503129 catenin, alpha-like 1 [Homo sapiens] 1419 0.0
gi|55770846 catenin, alpha 2 [Homo sapiens] 201 2e-51
gi|55770844 catenin, alpha 1 [Homo sapiens] 166 5e-41
gi|188497718 catenin, alpha 3 [Homo sapiens] 145 1e-34
gi|188497716 catenin, alpha 3 [Homo sapiens] 145 1e-34
gi|71061468 centromere protein E [Homo sapiens] 51 3e-06
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens] 44 4e-04
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens] 44 4e-04
gi|118498368 kinectin 1 isoform c [Homo sapiens] 43 0.001
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 43 0.001
gi|4504063 golgin 97 [Homo sapiens] 42 0.003
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 41 0.005
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 41 0.005
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 41 0.005
gi|109255234 centrosomal protein 290kDa [Homo sapiens] 40 0.006
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 40 0.006
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 40 0.008
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 40 0.008
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 40 0.008
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 40 0.008
gi|40807445 protein regulator of cytokinesis 1 isoform 3 [Homo s... 40 0.008
gi|40807443 protein regulator of cytokinesis 1 isoform 2 [Homo s... 40 0.008
gi|4506039 protein regulator of cytokinesis 1 isoform 1 [Homo sa... 40 0.008
gi|118498356 kinectin 1 isoform a [Homo sapiens] 39 0.017
gi|33620775 kinectin 1 isoform a [Homo sapiens] 39 0.017
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 39 0.023
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 39 0.023
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 39 0.023
gi|112734867 retinitis pigmentosa GTPase regulator interacting p... 38 0.029
gi|4507877 vinculin isoform VCL [Homo sapiens] 38 0.038
>gi|4503129 catenin, alpha-like 1 [Homo sapiens]
Length = 734
Score = 1419 bits (3674), Expect = 0.0
Identities = 734/734 (100%), Positives = 734/734 (100%)
Query: 1 MAASPGPAGVGGAGAVYGSGSSGFALDSGLEIKTRSVEQTLLPLVSQITTLINHKDNTKK 60
MAASPGPAGVGGAGAVYGSGSSGFALDSGLEIKTRSVEQTLLPLVSQITTLINHKDNTKK
Sbjct: 1 MAASPGPAGVGGAGAVYGSGSSGFALDSGLEIKTRSVEQTLLPLVSQITTLINHKDNTKK 60
Query: 61 SDKTLQAIQRVGQAVNLAVGRFVKVGEAIANENWDLKEEINIACIEAKQAGETIAALTDI 120
SDKTLQAIQRVGQAVNLAVGRFVKVGEAIANENWDLKEEINIACIEAKQAGETIAALTDI
Sbjct: 61 SDKTLQAIQRVGQAVNLAVGRFVKVGEAIANENWDLKEEINIACIEAKQAGETIAALTDI 120
Query: 121 TNLNHLESDGQITIFTDKTGVIKAARLLLSSVTKVLLLADRVVIKQIITSRNKVLATMER 180
TNLNHLESDGQITIFTDKTGVIKAARLLLSSVTKVLLLADRVVIKQIITSRNKVLATMER
Sbjct: 121 TNLNHLESDGQITIFTDKTGVIKAARLLLSSVTKVLLLADRVVIKQIITSRNKVLATMER 180
Query: 181 LEKVNSFQEFVQIFSQFGNEMVEFAHLSGDRQNDLKDEKKKAKMAAARAVLEKCTMMLLT 240
LEKVNSFQEFVQIFSQFGNEMVEFAHLSGDRQNDLKDEKKKAKMAAARAVLEKCTMMLLT
Sbjct: 181 LEKVNSFQEFVQIFSQFGNEMVEFAHLSGDRQNDLKDEKKKAKMAAARAVLEKCTMMLLT 240
Query: 241 ASKTCLRHPNCESAHKNKEGVFDRMKVALDKVIEIVTDCKPNGETDISSISIFTGIKEFK 300
ASKTCLRHPNCESAHKNKEGVFDRMKVALDKVIEIVTDCKPNGETDISSISIFTGIKEFK
Sbjct: 241 ASKTCLRHPNCESAHKNKEGVFDRMKVALDKVIEIVTDCKPNGETDISSISIFTGIKEFK 300
Query: 301 MNIEALRENLYFQSKENLSVTLEVILERMEDFTDSAYTSHEHRERILELSTQARMELQQL 360
MNIEALRENLYFQSKENLSVTLEVILERMEDFTDSAYTSHEHRERILELSTQARMELQQL
Sbjct: 301 MNIEALRENLYFQSKENLSVTLEVILERMEDFTDSAYTSHEHRERILELSTQARMELQQL 360
Query: 361 ISVWIQAQSKKTKSIAEELELSILKISHSLNELKKELHSTATQLAADLLKYHADHVVLKA 420
ISVWIQAQSKKTKSIAEELELSILKISHSLNELKKELHSTATQLAADLLKYHADHVVLKA
Sbjct: 361 ISVWIQAQSKKTKSIAEELELSILKISHSLNELKKELHSTATQLAADLLKYHADHVVLKA 420
Query: 421 LKLTGVEGNLEALAEYACKLSEQKEQLVETCRLLRHISGTEPLEITCIHAEETFQVTGQQ 480
LKLTGVEGNLEALAEYACKLSEQKEQLVETCRLLRHISGTEPLEITCIHAEETFQVTGQQ
Sbjct: 421 LKLTGVEGNLEALAEYACKLSEQKEQLVETCRLLRHISGTEPLEITCIHAEETFQVTGQQ 480
Query: 481 IISAAETLTLHPSSKIAKENLDVFCEAWESQISDMSTLLREINDVFEGRRGEKYGYLSLP 540
IISAAETLTLHPSSKIAKENLDVFCEAWESQISDMSTLLREINDVFEGRRGEKYGYLSLP
Sbjct: 481 IISAAETLTLHPSSKIAKENLDVFCEAWESQISDMSTLLREINDVFEGRRGEKYGYLSLP 540
Query: 541 KPMKNNANLKSLKPDKPDSEEQAKIAKLGLKLGLLTSDADCEIEKWEDQENEIVQYGRNM 600
KPMKNNANLKSLKPDKPDSEEQAKIAKLGLKLGLLTSDADCEIEKWEDQENEIVQYGRNM
Sbjct: 541 KPMKNNANLKSLKPDKPDSEEQAKIAKLGLKLGLLTSDADCEIEKWEDQENEIVQYGRNM 600
Query: 601 SSMAYSLYLFTRGEGPLKTSQDLIHQLEVFAAEGLKLTSSVQAFSKQLKDDDKLMLLLEI 660
SSMAYSLYLFTRGEGPLKTSQDLIHQLEVFAAEGLKLTSSVQAFSKQLKDDDKLMLLLEI
Sbjct: 601 SSMAYSLYLFTRGEGPLKTSQDLIHQLEVFAAEGLKLTSSVQAFSKQLKDDDKLMLLLEI 660
Query: 661 NKLIPLCHQLQTVTKTSLQNKVFLKVDKCITKTRSMMALLVQLLSLCYKLLKKLQMENNG 720
NKLIPLCHQLQTVTKTSLQNKVFLKVDKCITKTRSMMALLVQLLSLCYKLLKKLQMENNG
Sbjct: 661 NKLIPLCHQLQTVTKTSLQNKVFLKVDKCITKTRSMMALLVQLLSLCYKLLKKLQMENNG 720
Query: 721 WVSVTNKDTMDSKT 734
WVSVTNKDTMDSKT
Sbjct: 721 WVSVTNKDTMDSKT 734
>gi|55770846 catenin, alpha 2 [Homo sapiens]
Length = 905
Score = 201 bits (512), Expect = 2e-51
Identities = 150/506 (29%), Positives = 252/506 (49%), Gaps = 26/506 (5%)
Query: 30 LEIKTRSVEQTLLPLVSQITTLINHKD---NTKKSDKTLQAIQRVGQAVNLAVGRFVKVG 86
LEI+T +VE+ L PLV+Q+TTL+N + + KK ++ +A + +V A F++ G
Sbjct: 17 LEIRTLTVERLLEPLVTQVTTLVNTSNKGPSGKKKGRSKKA-HVLAASVEQATQNFLEKG 75
Query: 87 EAIANENWDLKEEINIACIEAKQAGETIAALTDITNLNHLESDGQITIFTDKTGVIKAAR 146
E IA E+ DLKEE+ A + ++ GET+ + E + +++AAR
Sbjct: 76 EQIAKESQDLKEELVAAVEDVRKQGETMRIASS-------EFADDPCSSVKRGTMVRAAR 128
Query: 147 LLLSSVTKVLLLADRVVIKQIITSRNKVLATMERLEKVNSFQEFVQIFSQFGNEMVEFAH 206
LLS+VT++L+LAD + ++++ V +E ++ + Q+ F +FG EMV+ +
Sbjct: 129 ALLSAVTRLLILADMADVMRLLSHLKIVEEALEAVKNATNEQDLANRFKEFGKEMVKLNY 188
Query: 207 LSGDRQNDLKDEKKKAKMAAARAVLEKCTMMLLTASKTCLRHPNCESAHKNKEGVFDRMK 266
++ RQ +LKD + +MAAAR L+K ML TAS+ LRHP+ + N++ VF +++
Sbjct: 189 VAARRQQELKDPHCRDEMAAARGALKKNATMLYTASQAFLRHPDVAATRANRDYVFKQVQ 248
Query: 267 VALDKVIEIVTDCKP----NGETDISSISIFTGIKEFKMNIEALRENLYFQS---KENLS 319
A+ + P G T I ++ + EF I + + + F + +L
Sbjct: 249 EAIAGISNAAQATSPTDEAKGHTGIGELA--AALNEFDNKI--ILDPMTFSEARFRPSLE 304
Query: 320 VTLEVILERMEDFTDSAYTSHEHRERILELSTQARMELQQLISVWIQAQSKKTKSIAEEL 379
LE I+ DS+ T + RERI+ R LQ L+S ++ +K K + L
Sbjct: 305 ERLESIISGAALMADSSCTRDDRRERIVAECNAVRQALQDLLSEYMNNTGRKEK--GDPL 362
Query: 380 ELSILKISHSLNELKKELHSTATQLAADLLKYHADHVVLKALKLTGVEGNLEALAEYACK 439
++I K++ +L+++L +D + +V L L GN + + EYA
Sbjct: 363 NIAIDKMTKKTRDLRRQLRKAVMDHISD--SFLETNVPLLVLIEAAKSGNEKEVKEYAQV 420
Query: 440 LSEQKEQLVETCRLLRHISGTEPLEITCIHAEETFQVTGQQIISAAETLTLHPSSKIAKE 499
E +LVE L IS E A Q+I+AA TL P SK+A++
Sbjct: 421 FREHANKLVEVANLACSISNNEEGVKLVRMAATQIDSLCPQVINAALTLAARPQSKVAQD 480
Query: 500 NLDVFCEAWESQISDMSTLLREINDV 525
N+DVF + WE Q+ ++ + +I V
Sbjct: 481 NMDVFKDQWEKQVRVLTEAVDDITSV 506
Score = 65.1 bits (157), Expect = 2e-10
Identities = 38/121 (31%), Positives = 61/121 (50%), Gaps = 1/121 (0%)
Query: 560 EEQAKIAKLGLKLGLLTSDADCEIEKWEDQENEIVQYGRNMSSMAYSLYLFTRGEGPLKT 619
EE+AKIA+ S D E+ KW+D N+I+ + M + + FTRG+GPLK
Sbjct: 678 EEKAKIAEQVEIFHQEKSKLDAEVAKWDDSGNDIIVLAKQMCMIMMEMTDFTRGKGPLKN 737
Query: 620 SQDLIHQLEVFAAEGLKLTSSVQAFSKQLKDDD-KLMLLLEINKLIPLCHQLQTVTKTSL 678
+ D+I+ + A G ++ +A + Q D K LL + ++ CHQL +K
Sbjct: 738 TSDVINAAKKIAEAGSRMDKLARAVADQCPDSACKQDLLAYLQRIALYCHQLNICSKVKA 797
Query: 679 Q 679
+
Sbjct: 798 E 798
>gi|55770844 catenin, alpha 1 [Homo sapiens]
Length = 906
Score = 166 bits (421), Expect = 5e-41
Identities = 139/520 (26%), Positives = 246/520 (47%), Gaps = 30/520 (5%)
Query: 19 SGSSGFALD-SGLEIKTRSVEQTLLPLVSQITTLINHKD---NTKKSDKTLQAIQRVGQA 74
+G+ F D LEI+T +VE+ L PLV+Q+TTL+N + KK ++ +A + +
Sbjct: 6 AGNINFKWDPKSLEIRTLAVERLLEPLVTQVTTLVNTNSKGPSNKKRGRSKKA-HVLAAS 64
Query: 75 VNLAVGRFVKVGEAIANENWDLKEEINIACIEAKQAGETIAALTDITNLNHLESDGQITI 134
V A F++ G+ IA E+ LKEE+ A + ++ G+ + A E
Sbjct: 65 VEQATENFLEKGDKIAKESQFLKEELVAAVEDVRKQGDLMKAAAG-------EFADDPCS 117
Query: 135 FTDKTGVIKAARLLLSSVTKVLLLADRVVIKQIITSRNKVLATMERLEKVNSFQEFVQIF 194
+ +++AAR LLS+VT++L+LAD + +++ V + +L + Q+ +
Sbjct: 118 SVKRGNMVRAARALLSAVTRLLILADMADVYKLLVQLKVVEDGILKLRNAGNEQDLGIQY 177
Query: 195 SQFGNEMVEFAHLSGDRQNDLKDEKKKAKMAAARAVLEKCTMMLLTASKTCLRHPNCESA 254
E+ + ++ RQ +LKD + +MAAAR +L+K +L TAS+ CL+HP+ +
Sbjct: 178 KALKPEVDKLNIMAAKRQQELKDVGHRDQMAAARGILQKNVPILYTASQACLQHPDVAAY 237
Query: 255 HKNKEGVFDRMKVALDKVIEIVTDCKPNGETDISSI------SIFTGIKEFKMNIEALRE 308
N++ ++ +++ A V I + D S + + F I + +
Sbjct: 238 KANRDLIYKQLQQA---VTGISNAAQATASDDASQHQGGGGGELAYALNNFDKQI--IVD 292
Query: 309 NLYFQS---KENLSVTLEVILERMEDFTDSAYTSHEHRERILELSTQARMELQQLISVWI 365
L F + +L LE I+ DS+ T + RERI+ R LQ L+S ++
Sbjct: 293 PLSFSEERFRPSLEERLESIISGAALMADSSCTRDDRRERIVAECNAVRQALQDLLSEYM 352
Query: 366 QAQSKKTKSIAEELELSILKISHSLNELKKELHSTATQLAADLLKYHADHVVLKALKLTG 425
+K +S + L +I K++ +L+++L +D + +V L L
Sbjct: 353 GNAGRKERS--DALNSAIDKMTKKTRDLRRQLRKAVMDHVSD--SFLETNVPLLVLIEAA 408
Query: 426 VEGNLEALAEYACKLSEQKEQLVETCRLLRHISGTEPLEITCIHAEETFQVTGQQIISAA 485
GN + + EYA E +L+E L IS E + + Q+I+AA
Sbjct: 409 KNGNEKEVKEYAQVFREHANKLIEVANLACSISNNEEGVKLVRMSASQLEALCPQVINAA 468
Query: 486 ETLTLHPSSKIAKENLDVFCEAWESQISDMSTLLREINDV 525
L P SK+A+EN+D+F E WE Q+ ++ + +I +
Sbjct: 469 LALAAKPQSKLAQENMDLFKEQWEKQVRVLTDAVDDITSI 508
Score = 62.0 bits (149), Expect = 2e-09
Identities = 45/166 (27%), Positives = 73/166 (43%), Gaps = 10/166 (6%)
Query: 560 EEQAKIAKLGLKLGLLTSDADCEIEKWEDQENEIVQYGRNMSSMAYSLYLFTRGEGPLKT 619
E++AKIA+ S D E+ KW+D N+I+ + M + + FTRG+GPLK
Sbjct: 679 EQKAKIAEQVASFQEEKSKLDAEVSKWDDSGNDIIVLAKQMCMIMMEMTDFTRGKGPLKN 738
Query: 620 SQDLIHQLEVFAAEGLKLTSSVQAFSKQLKDDD-KLMLLLEINKLIPLCHQLQTVTKTSL 678
+ D+I + A G ++ + + D K LL + ++ CHQL +K
Sbjct: 739 TSDVISAAKKIAEAGSRMDKLGRTIADHCPDSACKQDLLAYLQRIALYCHQLNICSKVKA 798
Query: 679 Q------NKVFLKVDKC---ITKTRSMMALLVQLLSLCYKLLKKLQ 715
+ V VD I +++M +VQ + Y K Q
Sbjct: 799 EVQNLGGELVVSGVDSAMSLIQAAKNLMNAVVQTVKASYVASTKYQ 844
>gi|188497718 catenin, alpha 3 [Homo sapiens]
Length = 895
Score = 145 bits (366), Expect = 1e-34
Identities = 125/506 (24%), Positives = 233/506 (46%), Gaps = 28/506 (5%)
Query: 30 LEIKTRSVEQTLLPLVSQITTLINHKDN--TKKSDKTLQAIQRVGQAVNLAVGRFVKVGE 87
L+++T +VE+ L PL+ Q+TTL+N N ++K ++ +A + +V A + GE
Sbjct: 16 LQVQTFTVEKLLEPLIIQVTTLVNCPQNPSSRKKGRSKRASVLLA-SVEEATWNLLDKGE 74
Query: 88 AIANENWDLKEEINIACIEAKQAGETIAALTDITNLNHLESDGQITIFTDKTGVIKAARL 147
IA E LK+E+ + E ++ E + + + V++AAR
Sbjct: 75 KIAQEATVLKDELTASLEEVRKESEALKVSAE-------RFTDDPCFLPKREAVVQAARA 127
Query: 148 LLSSVTKVLLLADRVVIKQIITSRNKVLATMERLEKVNSFQEFVQIFSQFGNEMVEFAHL 207
LL++VT++L+LAD + + ++ + T E L+ V + + + + + G E+ +L
Sbjct: 128 LLAAVTRLLILADMIDVMCLLQHVSAFQRTFESLKNVANKSDLQKTYQKLGKELENLDYL 187
Query: 208 SGDRQNDLKDEKKKAKMAAARAVLEKCTMMLLTASKTCLRHPNCESAHKNKEGVFDRMKV 267
+ RQ DLK ++ ++A ARA L++ + +L + CL H + S +K+ V + ++
Sbjct: 188 AFKRQQDLKSPNQRDEIAGARASLKENSPLLHSICSACLEHSDVASLKASKDTVCEEIQN 247
Query: 268 ALDKVI-------EIVTDCKPNGETDISSISIFTGIKEFKMNIEALRENLYFQSKENLSV 320
AL+ + + T +P T S++ + +N + E + + +L
Sbjct: 248 ALNVISNASQGIQNMTTPPEPQAATLGSALDELENL--IVLNPLTVTEE---EIRPSLEK 302
Query: 321 TLEVILERMEDFTDSAYTSHEHRERILELSTQARMELQQLISVWIQAQSKKTKSIAEELE 380
LE I+ DS+ T HRERI+ R LQ L+S ++ KK +S L
Sbjct: 303 RLEAIISGAALLADSSCTRDLHRERIIAECNAIRQALQDLLSEYMNNAGKKERS--NTLN 360
Query: 381 LSILKISHSLNELKKELHSTATQLAADLLKYHADHVVLKALKLTGVEGNLEALAEYACKL 440
+++ + +L+++L +D + V L L G + + EYA
Sbjct: 361 IALDNMCKKTRDLRRQLRKAIIDHVSD--SFLDTTVPLLVLIEAAKNGREKEIKEYAAIF 418
Query: 441 SEQKEQLVETCRLLRHISGTEP-LEITCIHAEETFQVTGQQIISAAETLTLHPSSKIAKE 499
E +LVE L +S E ++I I A + QII+AA L P S+ K
Sbjct: 419 HEHTSRLVEVANLACSMSTNEDGIKIVKIAANH-LETLCPQIINAALALAARPKSQAVKN 477
Query: 500 NLDVFCEAWESQISDMSTLLREINDV 525
++++ WE+ I ++ + +I +
Sbjct: 478 TMEMYKRTWENHIHVLTEAVDDITSI 503
Score = 62.4 bits (150), Expect = 1e-09
Identities = 44/162 (27%), Positives = 79/162 (48%), Gaps = 11/162 (6%)
Query: 557 PDSEEQAKIAKLGLKLGLLTSDADCEIEKWEDQENEIVQYGRNMSSMAYSLYLFTRGEGP 616
P++E++ KIA+ + S D EIE W+D N+I+ +NM + + FTRG+GP
Sbjct: 666 PEAEKE-KIAEQVADFKKVKSKLDAEIEIWDDTSNDIIVLAKNMCMIMMEMTDFTRGKGP 724
Query: 617 LKTSQDLIHQLEVFAAEGLKLTSSVQAFSKQLKDDD-KLMLLLEINKLIPLCHQLQ--TV 673
LK + D+I+ ++ + G ++ + + Q D K LL + ++ HQL+ +
Sbjct: 725 LKHTTDVIYAAKMISESGSRMDVLARQIANQCPDPSCKQDLLAYLEQIKFYSHQLKICSQ 784
Query: 674 TKTSLQN-------KVFLKVDKCITKTRSMMALLVQLLSLCY 708
K +QN V I +++M +VQ + + Y
Sbjct: 785 VKAEIQNLGGELIMSALDSVTSLIQAAKNLMNAVVQTVKMSY 826
>gi|188497716 catenin, alpha 3 [Homo sapiens]
Length = 895
Score = 145 bits (366), Expect = 1e-34
Identities = 125/506 (24%), Positives = 233/506 (46%), Gaps = 28/506 (5%)
Query: 30 LEIKTRSVEQTLLPLVSQITTLINHKDN--TKKSDKTLQAIQRVGQAVNLAVGRFVKVGE 87
L+++T +VE+ L PL+ Q+TTL+N N ++K ++ +A + +V A + GE
Sbjct: 16 LQVQTFTVEKLLEPLIIQVTTLVNCPQNPSSRKKGRSKRASVLLA-SVEEATWNLLDKGE 74
Query: 88 AIANENWDLKEEINIACIEAKQAGETIAALTDITNLNHLESDGQITIFTDKTGVIKAARL 147
IA E LK+E+ + E ++ E + + + V++AAR
Sbjct: 75 KIAQEATVLKDELTASLEEVRKESEALKVSAE-------RFTDDPCFLPKREAVVQAARA 127
Query: 148 LLSSVTKVLLLADRVVIKQIITSRNKVLATMERLEKVNSFQEFVQIFSQFGNEMVEFAHL 207
LL++VT++L+LAD + + ++ + T E L+ V + + + + + G E+ +L
Sbjct: 128 LLAAVTRLLILADMIDVMCLLQHVSAFQRTFESLKNVANKSDLQKTYQKLGKELENLDYL 187
Query: 208 SGDRQNDLKDEKKKAKMAAARAVLEKCTMMLLTASKTCLRHPNCESAHKNKEGVFDRMKV 267
+ RQ DLK ++ ++A ARA L++ + +L + CL H + S +K+ V + ++
Sbjct: 188 AFKRQQDLKSPNQRDEIAGARASLKENSPLLHSICSACLEHSDVASLKASKDTVCEEIQN 247
Query: 268 ALDKVI-------EIVTDCKPNGETDISSISIFTGIKEFKMNIEALRENLYFQSKENLSV 320
AL+ + + T +P T S++ + +N + E + + +L
Sbjct: 248 ALNVISNASQGIQNMTTPPEPQAATLGSALDELENL--IVLNPLTVTEE---EIRPSLEK 302
Query: 321 TLEVILERMEDFTDSAYTSHEHRERILELSTQARMELQQLISVWIQAQSKKTKSIAEELE 380
LE I+ DS+ T HRERI+ R LQ L+S ++ KK +S L
Sbjct: 303 RLEAIISGAALLADSSCTRDLHRERIIAECNAIRQALQDLLSEYMNNAGKKERS--NTLN 360
Query: 381 LSILKISHSLNELKKELHSTATQLAADLLKYHADHVVLKALKLTGVEGNLEALAEYACKL 440
+++ + +L+++L +D + V L L G + + EYA
Sbjct: 361 IALDNMCKKTRDLRRQLRKAIIDHVSD--SFLDTTVPLLVLIEAAKNGREKEIKEYAAIF 418
Query: 441 SEQKEQLVETCRLLRHISGTEP-LEITCIHAEETFQVTGQQIISAAETLTLHPSSKIAKE 499
E +LVE L +S E ++I I A + QII+AA L P S+ K
Sbjct: 419 HEHTSRLVEVANLACSMSTNEDGIKIVKIAANH-LETLCPQIINAALALAARPKSQAVKN 477
Query: 500 NLDVFCEAWESQISDMSTLLREINDV 525
++++ WE+ I ++ + +I +
Sbjct: 478 TMEMYKRTWENHIHVLTEAVDDITSI 503
Score = 62.4 bits (150), Expect = 1e-09
Identities = 44/162 (27%), Positives = 79/162 (48%), Gaps = 11/162 (6%)
Query: 557 PDSEEQAKIAKLGLKLGLLTSDADCEIEKWEDQENEIVQYGRNMSSMAYSLYLFTRGEGP 616
P++E++ KIA+ + S D EIE W+D N+I+ +NM + + FTRG+GP
Sbjct: 666 PEAEKE-KIAEQVADFKKVKSKLDAEIEIWDDTSNDIIVLAKNMCMIMMEMTDFTRGKGP 724
Query: 617 LKTSQDLIHQLEVFAAEGLKLTSSVQAFSKQLKDDD-KLMLLLEINKLIPLCHQLQ--TV 673
LK + D+I+ ++ + G ++ + + Q D K LL + ++ HQL+ +
Sbjct: 725 LKHTTDVIYAAKMISESGSRMDVLARQIANQCPDPSCKQDLLAYLEQIKFYSHQLKICSQ 784
Query: 674 TKTSLQN-------KVFLKVDKCITKTRSMMALLVQLLSLCY 708
K +QN V I +++M +VQ + + Y
Sbjct: 785 VKAEIQNLGGELIMSALDSVTSLIQAAKNLMNAVVQTVKMSY 826
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 51.2 bits (121), Expect = 3e-06
Identities = 156/739 (21%), Positives = 281/739 (38%), Gaps = 144/739 (19%)
Query: 31 EIKTRSVEQTLLPLVSQITTLINHKDNTKKSDKTLQAIQRVGQAVNLAVGRFVKVGEAIA 90
E+ +E L L ++ + K K L+ +Q+ + + +++ EA
Sbjct: 1171 ELTLEHMETERLELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATG 1230
Query: 91 NENWDLKEEINIACIEAKQAGETIAAL--------TDITNLNHLESDGQITIFTDKTGVI 142
+ KEE+ IA I K+ ETI L I N LE T ++ V+
Sbjct: 1231 LQT---KEELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQDLEKSH--TKLQEEIPVL 1285
Query: 143 KAARLLLSSVTKVLLLADRVVIKQIIT--SRNKVLATMERLEKVNSFQEFVQIFSQFGNE 200
+ LL +V +V + + +++T S K T+ R+E E +++ +F
Sbjct: 1286 HEEQELLPNVKEVSETQETMNELELLTEQSTTKDSTTLARIE-----MERLRLNEKFQES 1340
Query: 201 MVEFAHLSGDRQN--------DLKDEKKK-------AKMAAARAVLEKCTMM-------- 237
E L+ +R N ++K ++ K AK+ +++ E+ M
Sbjct: 1341 QEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQSLNMKEKDNETT 1400
Query: 238 ----------------------LLTASKTCLR-HPNCESAHKNKEGVFDRMKVALDKVIE 274
+L SK H +S K K+ + +V + +
Sbjct: 1401 KIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQ 1460
Query: 275 IVTDCKP----NGETDISSISIFTGIKEFKMNIEALRENLYFQSKE--NLSVTLEVILER 328
+ + K + ET+ +KE + I LR NL + E + LE I ++
Sbjct: 1461 LKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEKETEISTIQKQLEAINDK 1520
Query: 329 MEDFTDSAYTSHE--HRERILELSTQARMELQQLISVWIQAQSKKTKSIAEELELSILKI 386
+++ Y E + ++I E+ + EL+Q + K S + +E +L++
Sbjct: 1521 LQNKIQEIYEKEEQFNIKQISEVQEKVN-ELKQF-----KEHRKAKDSALQSIESKMLEL 1574
Query: 387 SHSLNELKKELH------------STATQLAADLLKYHADHVVLKA----------LKLT 424
++ L E ++E+ A Q+ D LK + +V K LK+T
Sbjct: 1575 TNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLKENTKEIVAKMKESQEKEYQFLKMT 1634
Query: 425 GVEGNLEALAEYACKLSEQKEQLVETCRLLRHISGTEPLEITCI---HAEETFQVTGQQ- 480
V E + C++ KEQ ET +L TE + +T I + EE VT ++
Sbjct: 1635 AVNETQEKM----CEIEHLKEQF-ETQKLNLENIETENIRLTQILHENLEEMRSVTKERD 1689
Query: 481 -IISAAETLTLHPSSKIAKENL-DVFCEAWESQ--ISDMSTLLREINDVFEGRRG---EK 533
+ S ETL + KENL + E Q + + L+E + + RG EK
Sbjct: 1690 DLRSVEETLKVERDQ--LKENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEK 1747
Query: 534 YGYLSLPKPMKNNANLKSLKPDKPDSEEQAKIAKLGLK---------LGLLTSDADCEIE 584
+S + ++N +LK +E+ +IA + LK G+++ D
Sbjct: 1748 TNEISNMQKDLEHSN-DALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSN 1806
Query: 585 KWEDQENEIVQYGRNMSSMAYSLYLFTRGEGPLKTSQDLIHQLEVFAAEGLKLTSSVQAF 644
+D EN + + LK ++ + L+ E K S ++
Sbjct: 1807 MQKDLENSNAKLQEKIQE--------------LKANEHQLITLKKDVNETQKKVSEMEQL 1852
Query: 645 SKQLKDDDKLMLLLEINKL 663
KQ+KD + LEI L
Sbjct: 1853 KKQIKDQSLTLSKLEIENL 1871
Score = 43.1 bits (100), Expect = 0.001
Identities = 141/766 (18%), Positives = 300/766 (39%), Gaps = 126/766 (16%)
Query: 21 SSGFALDSGLEIKTRSVEQTLLPLVSQITTLINHKDNTKKSDKTLQAIQRVGQAVNLAVG 80
SS AL + L KT+ +++ + ++ + K+ + D TLQ ++R + +
Sbjct: 859 SSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQ 918
Query: 81 RFVKVGEAIANENWDLKEEINIACIEAKQAGETIAALTDITNLNHLESDGQITIFTDKTG 140
+ ++ + + E DLK+ IE Q I D N+N +++ Q+
Sbjct: 919 QTLEEVKTLTQEKDDLKQLQESLQIERDQLKSDI---HDTVNMN-IDTQEQL-------- 966
Query: 141 VIKAARLLLSSVTKVLLLADRVVIKQIITSRNKVLATMERLEKVNSFQEFVQIFSQFGNE 200
RN + + + E +N+ + S+ E
Sbjct: 967 ------------------------------RNALESLKQHQETINTLK------SKISEE 990
Query: 201 MVEFAHLSGDRQNDLKDE-KKKAKMAAARAVLEKCTMMLLTA----SKTCLRHPNCESAH 255
+ H+ + + KDE ++K + LE LTA ++ + S
Sbjct: 991 VSRNLHME-ENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLI 1049
Query: 256 KNKEGVFDRMKVALDKVIEIVTDCKPNGETDISS---ISIFTGIKEFKMNIEALRENLYF 312
+ K + ++ + + ++ TD K N E I + + + + + I A +N
Sbjct: 1050 QEKNELQQMLESVIAEKEQLKTDLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAI 1109
Query: 313 QSKENLSVTLEVILERMEDFTDSAYTSHEHRERILELSTQARMELQQLISVW--IQAQSK 370
+ + LS T + + E E + + E ++++L + + E+Q+ I+ ++ + K
Sbjct: 1110 KKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQ-EEMSEMQKKINEIENLKNELK 1168
Query: 371 KTKSIAEELELSILKISHSLNELKKELHSTATQ--LAADLLK---YHADHV--VLKALKL 423
+ E +E L+++ LNE +E+ S + + +L K DH+ ++ ++
Sbjct: 1169 NKELTLEHMETERLELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEA 1228
Query: 424 TGVE-------------GNLEALAEYACKLSEQKEQLVETCRLLRHISGTEPLEITCIHA 470
TG++ + E + E +SE+ Q++ T L + + + EI +H
Sbjct: 1229 TGLQTKEELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQE-EIPVLHE 1287
Query: 471 EETFQVTGQQIISAAETLTLHPSSKIAKENLDVFCEAWESQISDMSTLLR------EIND 524
E+ +++ ET+ L++ E +S D +TL R +N+
Sbjct: 1288 EQELLPNVKEVSETQETM----------NELELLTE--QSTTKDSTTLARIEMERLRLNE 1335
Query: 525 VFEGRRGEKYGYLSLPKPMKNNANLKSLKPDKPDS------EEQAKI----AKLGLKLGL 574
F+ + E SL K N +K K D E AKI +K L +
Sbjct: 1336 KFQESQEE---IKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQSLNM 1392
Query: 575 LTSDAD-----CEIEKWEDQENEIVQYGRNMSSMAYSLY-LFTRGEGPLKTSQDLIHQLE 628
D + E+E+++ +++ +++ M ++ L + K DL E
Sbjct: 1393 KEKDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQE 1452
Query: 629 VFAAEGLKLTSSV-QAFSKQLKDDDKLMLLLEINKLIPLCHQLQTVTKTSLQNKVFLKVD 687
V +E +L ++ + +K L+ +++L K+ C + Q T L+ + K
Sbjct: 1453 VLQSESDQLKENIKEIVAKHLETEEEL-------KVAHCCLKEQEETINELRVNLSEKET 1505
Query: 688 KCITKTRSMMALLVQLLSLCYKLLKKLQMENNGWVSVTNKDTMDSK 733
+ T + + A+ +L + ++ +K + N +S + + K
Sbjct: 1506 EISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNELK 1551
Score = 36.6 bits (83), Expect = 0.086
Identities = 111/563 (19%), Positives = 207/563 (36%), Gaps = 95/563 (16%)
Query: 37 VEQTLLPLVSQITTLINHKDNTKKSDKTLQAIQRVGQAVNLAVGRFVKVGEAIANENWDL 96
+E +L L ++ + + K LQ +Q V Q+ + + +K I ++ +
Sbjct: 1419 IEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIK---EIVAKHLET 1475
Query: 97 KEEINIACIEAKQAGETIAALTDITNLNHLESDGQITIFTDKTGVIKAARLLLSSVTKVL 156
+EE+ +A K+ ETI L +N E + +I+ + I L + + ++
Sbjct: 1476 EEELKVAHCCLKEQEETINEL----RVNLSEKETEISTIQKQLEAINDK--LQNKIQEIY 1529
Query: 157 LLADRVVIKQIITSRNKV---------------------LATMERLEKVNSFQEFVQIFS 195
++ IKQI + KV +E ++ QE +QI
Sbjct: 1530 EKEEQFNIKQISEVQEKVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMI 1589
Query: 196 QFGNEMVEFAHLSGDRQNDLKDEKKKAKMAAARAVLEKCTMMLLTASKTCLRHPNCESAH 255
+ EM ++ LK+ K+ +A + EK L + + CE H
Sbjct: 1590 KEKEEMKRVQEALQIERDQLKENTKEI-VAKMKESQEKEYQFLKMTAVNETQEKMCEIEH 1648
Query: 256 KNKEGVFDRMKVALDKV----IEIVTDCKPNGETDISSISIFTGIKEFKMNIEALRENLY 311
++ F+ K+ L+ + I + N E S ++ + ++ R+ L
Sbjct: 1649 LKEQ--FETQKLNLENIETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQL- 1705
Query: 312 FQSKENLSVTLEVILERMEDFTDSAYTSHEHRERI------------------------- 346
KENL T+ LE+ E+ EH+E I
Sbjct: 1706 ---KENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSN 1762
Query: 347 -------LELSTQARM------ELQQLISVWIQAQSKKTKSIA---EELELSILKISHSL 390
L++ + R+ E Q+ I S+KT ++ ++LE S K+ +
Sbjct: 1763 DALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKI 1822
Query: 391 NELKKELHS--------TATQLAADLLKYHADHVVLKALKLTGVE-GNLEALAEYACKLS 441
ELK H TQ ++ + ++L L+ +E NL + L
Sbjct: 1823 QELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQKLHENLE 1882
Query: 442 EQKEQLVETCRLLRHISGTEPLEITCIHAEETFQVTGQQIISAAETL-TLHPSSKIAKEN 500
E K + E L R E L++ +E+ Q T + + + L T SK KE
Sbjct: 1883 EMKSVMKERDNLRR---VEETLKLERDQLKESLQETKARDLEIQQELKTARMLSKEHKET 1939
Query: 501 LDVFCEAWESQISDMSTLLREIN 523
+D E + +S + ++++
Sbjct: 1940 VDKLREKISEKTIQISDIQKDLD 1962
Score = 30.4 bits (67), Expect = 6.1
Identities = 51/204 (25%), Positives = 82/204 (40%), Gaps = 31/204 (15%)
Query: 296 IKEFKMNIEALRENLYFQSKENLSVTLEVILERMED------------------FTDSAY 337
++E + I+ L+E + Q EN+ + L LE +ED +SA+
Sbjct: 584 LREKEDQIKKLQEYIDSQKLENIKMDLSYSLESIEDPKQMKQTLFDAETVALDAKRESAF 643
Query: 338 TSHEH---RERILELSTQARMELQQLISVWIQAQSKKTKSIAEELELSILKISHSLNELK 394
E+ +E++ EL+T + + Q ++KK + E EL + NE+
Sbjct: 644 LRSENLELKEKMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKEL-----QSAFNEIT 698
Query: 395 KELHSTATQLAADL---LKYHADHVVLKALKLTGVEGNLEALAEYACKLSEQKEQLVETC 451
K ++ DL L+ L+ VE N EAL E LSE K E
Sbjct: 699 KLTSLIDGKVPKDLLCNLELEGKITDLQKELNKEVEEN-EALREEVILLSELKSLPSEVE 757
Query: 452 RLLRHISG-TEPLEITCIHAEETF 474
RL + I +E L I ++ F
Sbjct: 758 RLRKEIQDKSEELHIITSEKDKLF 781
>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
Length = 3907
Score = 44.3 bits (103), Expect = 4e-04
Identities = 105/516 (20%), Positives = 211/516 (40%), Gaps = 63/516 (12%)
Query: 205 AHLSGDRQNDLKDEKKKAKMAAARAVLEKCTMMLLTASKTCLRHPNCESAHKNKEGVFDR 264
AH S DLK E A + +R LE +T K L E K K V DR
Sbjct: 561 AHKSLSTVEDLKAEIVSA--SESRKELELKHEAEVTNYKIKL-----EMLEKEKNAVLDR 613
Query: 265 MKVALDKVIE-IVTDCKPNGETDISSISIFTGIKEFKMNIEALRENLYFQSKENLSVTLE 323
M + + +E + T + E ++S + I E ++NIE L++NL K+ +
Sbjct: 614 MAESQEAELERLRTQLLFSHEEELSKLKEDLEI-EHRINIEKLKDNLGIHYKQQIDGLQN 672
Query: 324 VILERMEDFTDSAYTSHEHRERILELSTQARMELQQLISVWIQAQSKKTKSIAEELELSI 383
+ +++E T ++ ++ Q +E+ +L + Q S +EE+ L I
Sbjct: 673 EMSQKIE-------TMQFEKDNLITKQNQLILEISKLKDL----QQSLVNSKSEEMTLQI 721
Query: 384 LKISHSLNELKKELHSTATQLAADLLKYHADHVVLKALKLTGVEGNLEALAEYACKLSEQ 443
++ + L++E T L+ + LK L + + E L E+
Sbjct: 722 NELQKEIEILRQEEKEKGT------LEQEVQELQLKTELLE------KQMKEKENDLQEK 769
Query: 444 KEQLVETCRLLRHISGTEPLEITCIHAEETFQVTGQQIISAAETLTLHPSSKIAKENLDV 503
QL +L+ T ++ IH V+ ++ + +++ + ++ +++
Sbjct: 770 FAQLEAENSILKDEKKTLE-DMLKIHTP----VSQEERLIFLDSIKSKSKDSVWEKEIEI 824
Query: 504 FCEAWESQISDMSTLLREINDVFEGRRG-----EKYGYLSLPKPMKNNANLKSLKPDKPD 558
E E D+ ++N+ E +R EK ++ + + A L +K D D
Sbjct: 825 LIEENE----DLKQQCIQLNEEIEKQRNTFSFAEKNFEVNYQELQEEYACLLKVKDDLED 880
Query: 559 SEEQAKIAKLGLKLGLLTSDADCEIEKWEDQENEIVQYGRNMSSMAYSLYLFTRGEGPLK 618
S+ + ++ + KL L + + + + + + + +A +L + GE K
Sbjct: 881 SKNKQEL-EYKSKLKALNEELHLQRINPTTVKMKSSVFDEDKTFVAETLEM---GEVVEK 936
Query: 619 TSQDLIHQLEVFAAEGLKLTSSVQAFSKQLK---------DDDKLMLLLEINKLIPLCHQ 669
+ +L+ +LEV E L+L+ + S+QLK +++ L E ++ C +
Sbjct: 937 DTTELMEKLEVTKREKLELSQRLSDLSEQLKQKHGEISFLNEEVKSLKQEKEQVSLRCRE 996
Query: 670 LQTVTKTSLQNKVFLKVDKCITKTRSMMALLVQLLS 705
L+ + + + V C T+ S++ +V + S
Sbjct: 997 LEII----INHNRAENVQSCDTQVSSLLDGVVTMTS 1028
Score = 37.4 bits (85), Expect = 0.050
Identities = 92/458 (20%), Positives = 168/458 (36%), Gaps = 66/458 (14%)
Query: 322 LEVILERMEDFTDSAYTSHEHRERILELSTQARMELQQLISVWIQAQSKKTKSIAE---- 377
LE LE+M F D EH + + Q + +++ + +T+ + +
Sbjct: 2058 LEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLANH 2117
Query: 378 ---------ELELSILKISHSLNELKKELH---------STATQLAADLLKYHADHV--- 416
EL LS ++ + E +E+ A ++AD + D
Sbjct: 2118 LKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKHFG 2177
Query: 417 VLKALKLTGVEGNLEALAEYACKLSEQKEQLVETCRLLRHISGTEPLEITCIHAEETFQV 476
++A +E L+A + + ++ L E R + E+ +H Q+
Sbjct: 2178 AVEAKPELSLEVQLQAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLH----MQL 2233
Query: 477 TGQQIISAAETLTLHPSSKIAKENLD----VFCEAWESQISDMSTLLREINDVFEGRRGE 532
Q+ S L +K+ K++++ E+ D L + + + + E
Sbjct: 2234 EIQKKESTTRLQELEQENKLFKDDMEKLGLAIKESDAMSTQDQHVLFGKFAQIIQEKEVE 2293
Query: 533 KYGYLSLPKPMKNNANLKSLKPDKPDSEEQAKIAKLGLKLGLLTSDADC-------EIEK 585
L+ + K LK +K E+ I L ++ L SD +C EIE+
Sbjct: 2294 -IDQLN-EQVTKLQQQLKITTDNKVIEEKNELIRDLETQIECLMSDQECVKRNREEEIEQ 2351
Query: 586 W----EDQENEIVQYGRNMSSMAYSLYLFTRGEGPLKTSQDLIHQLEVFAAEGLKLTSSV 641
E + E+ G+ S A+SL + + L HQL+V AE L L V
Sbjct: 2352 LNEVIEKLQQELANIGQKTSMNAHSL---------SEEADSLKHQLDVVIAEKLALEQQV 2402
Query: 642 Q------AFSKQLKDDDKLMLLLEINKLIPLCHQLQTVTKTSL--QNKVFLKVDKCITKT 693
+ F K + + + +L L + ++V K +N V + +D
Sbjct: 2403 ETANEEMTFMKNVLKETNFKMNQLTQELFSLKRERESVEKIQSIPENSVNVAIDHLSKDK 2462
Query: 694 RSMMALLVQ--LLSLCYKLLKKLQMENNGWVSVTNKDT 729
+ +L + L SL + K E NG S+ N +T
Sbjct: 2463 PELEVVLTEDALKSLENQTYFK-SFEENGKGSIINLET 2499
>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
Length = 3899
Score = 44.3 bits (103), Expect = 4e-04
Identities = 105/516 (20%), Positives = 211/516 (40%), Gaps = 63/516 (12%)
Query: 205 AHLSGDRQNDLKDEKKKAKMAAARAVLEKCTMMLLTASKTCLRHPNCESAHKNKEGVFDR 264
AH S DLK E A + +R LE +T K L E K K V DR
Sbjct: 561 AHKSLSTVEDLKAEIVSA--SESRKELELKHEAEVTNYKIKL-----EMLEKEKNAVLDR 613
Query: 265 MKVALDKVIE-IVTDCKPNGETDISSISIFTGIKEFKMNIEALRENLYFQSKENLSVTLE 323
M + + +E + T + E ++S + I E ++NIE L++NL K+ +
Sbjct: 614 MAESQEAELERLRTQLLFSHEEELSKLKEDLEI-EHRINIEKLKDNLGIHYKQQIDGLQN 672
Query: 324 VILERMEDFTDSAYTSHEHRERILELSTQARMELQQLISVWIQAQSKKTKSIAEELELSI 383
+ +++E T ++ ++ Q +E+ +L + Q S +EE+ L I
Sbjct: 673 EMSQKIE-------TMQFEKDNLITKQNQLILEISKLKDL----QQSLVNSKSEEMTLQI 721
Query: 384 LKISHSLNELKKELHSTATQLAADLLKYHADHVVLKALKLTGVEGNLEALAEYACKLSEQ 443
++ + L++E T L+ + LK L + + E L E+
Sbjct: 722 NELQKEIEILRQEEKEKGT------LEQEVQELQLKTELLE------KQMKEKENDLQEK 769
Query: 444 KEQLVETCRLLRHISGTEPLEITCIHAEETFQVTGQQIISAAETLTLHPSSKIAKENLDV 503
QL +L+ T ++ IH V+ ++ + +++ + ++ +++
Sbjct: 770 FAQLEAENSILKDEKKTLE-DMLKIHTP----VSQEERLIFLDSIKSKSKDSVWEKEIEI 824
Query: 504 FCEAWESQISDMSTLLREINDVFEGRRG-----EKYGYLSLPKPMKNNANLKSLKPDKPD 558
E E D+ ++N+ E +R EK ++ + + A L +K D D
Sbjct: 825 LIEENE----DLKQQCIQLNEEIEKQRNTFSFAEKNFEVNYQELQEEYACLLKVKDDLED 880
Query: 559 SEEQAKIAKLGLKLGLLTSDADCEIEKWEDQENEIVQYGRNMSSMAYSLYLFTRGEGPLK 618
S+ + ++ + KL L + + + + + + + +A +L + GE K
Sbjct: 881 SKNKQEL-EYKSKLKALNEELHLQRINPTTVKMKSSVFDEDKTFVAETLEM---GEVVEK 936
Query: 619 TSQDLIHQLEVFAAEGLKLTSSVQAFSKQLK---------DDDKLMLLLEINKLIPLCHQ 669
+ +L+ +LEV E L+L+ + S+QLK +++ L E ++ C +
Sbjct: 937 DTTELMEKLEVTKREKLELSQRLSDLSEQLKQKHGEISFLNEEVKSLKQEKEQVSLRCRE 996
Query: 670 LQTVTKTSLQNKVFLKVDKCITKTRSMMALLVQLLS 705
L+ + + + V C T+ S++ +V + S
Sbjct: 997 LEII----INHNRAENVQSCDTQVSSLLDGVVTMTS 1028
Score = 40.4 bits (93), Expect = 0.006
Identities = 97/451 (21%), Positives = 168/451 (37%), Gaps = 60/451 (13%)
Query: 322 LEVILERMEDFTDSAYTSHEHRERILELSTQARMELQQLISVWIQA----QSKKTKSIAE 377
LE LE+M F D EH + + Q ++E Q + Q Q+++ + +A
Sbjct: 2058 LEKQLEKMRKFLDEQAIDREHERDVFQQEIQ-KLEQQLKVVPRFQPISEHQTREVEQLAN 2116
Query: 378 ELELSILKISHSL-------------NELKKELHSTATQLAADLLKYHADHV-VLKALKL 423
L+ K S L NE ++L +L LL H ++A
Sbjct: 2117 HLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALLVEDRKHFGAVEAKPE 2176
Query: 424 TGVEGNLEALAEYACKLSEQKEQLVETCRLLRHISGTEPLEITCIHAEETFQVTGQQIIS 483
+E L+A + + ++ L E R + E+ +H Q+ Q+ S
Sbjct: 2177 LSLEVQLQAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLH----MQLEIQKKES 2232
Query: 484 AAETLTLHPSSKIAKENLD----VFCEAWESQISDMSTLLREINDVFEGRRGEKYGYLSL 539
L +K+ K++++ E+ D L + + + + E L+
Sbjct: 2233 TTRLQELEQENKLFKDDMEKLGLAIKESDAMSTQDQHVLFGKFAQIIQEKEVE-IDQLN- 2290
Query: 540 PKPMKNNANLKSLKPDKPDSEEQAKIAKLGLKLGLLTSDADC-------EIEKW----ED 588
+ K LK +K E+ I L ++ L SD +C EIE+ E
Sbjct: 2291 EQVTKLQQQLKITTDNKVIEEKNELIRDLETQIECLMSDQECVKRNREEEIEQLNEVIEK 2350
Query: 589 QENEIVQYGRNMSSMAYSLYLFTRGEGPLKTSQDLIHQLEVFAAEGLKLTSSVQ------ 642
+ E+ G+ S A+SL + + L HQL+V AE L L V+
Sbjct: 2351 LQQELANIGQKTSMNAHSL---------SEEADSLKHQLDVVIAEKLALEQQVETANEEM 2401
Query: 643 AFSKQLKDDDKLMLLLEINKLIPLCHQLQTVTKTSL--QNKVFLKVDKCITKTRSMMALL 700
F K + + + +L L + ++V K +N V + +D + +L
Sbjct: 2402 TFMKNVLKETNFKMNQLTQELFSLKRERESVEKIQSIPENSVNVAIDHLSKDKPELEVVL 2461
Query: 701 VQ--LLSLCYKLLKKLQMENNGWVSVTNKDT 729
+ L SL + K E NG S+ N +T
Sbjct: 2462 TEDALKSLENQTYFK-SFEENGKGSIINLET 2491
>gi|118498368 kinectin 1 isoform c [Homo sapiens]
Length = 1300
Score = 43.1 bits (100), Expect = 0.001
Identities = 72/315 (22%), Positives = 137/315 (43%), Gaps = 31/315 (9%)
Query: 365 IQAQSKKTKSIAEELELSILKISH---SLNELKKELHSTATQLA-ADLLKYHADHVVLKA 420
I + K KS+ E LE +LK+++ ++ +LK+E+ + ++ L K + K
Sbjct: 803 IHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKV 862
Query: 421 LKLTG-VEGNLEALAEYACKLSEQKEQLVETCRLLRHISGTEPLEITCIHAEETFQVTGQ 479
+L ++G E + L E+++ L T + L+ + E E H +E Q +
Sbjct: 863 QELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQ--EENESLKAHVQEVAQHNLK 920
Query: 480 QIISAAETLTLHPSSKIAKEN----LDVFCEAWESQISDMSTLLREINDVFEGRRGEKYG 535
+ SA++ L K KEN L+ + ES +S + LL+++ D E
Sbjct: 921 EASSASQFEELEIVLK-EKENELKRLEAMLKERESDLSSKTQLLQDVQD-------ENKL 972
Query: 536 YLSLPKPMK--NNANLKSLKPD----KPDSEEQAKIAKLGLKLGLLTSDADCEIEKWEDQ 589
+ S + +K N S P K SE + +I+ L +L L + + +K ++
Sbjct: 973 FKSQIEQLKQQNYQQASSFPPHEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNER 1032
Query: 590 ENEIVQYGRNMSSMAYSLYLFTRGEGPLKTSQ-DLIHQLEVFAAEGLKLTS---SVQAFS 645
+ ++ + + LF + P S + +H E A E + TS V+
Sbjct: 1033 QQQVEAV--ELEAKEVLKKLFPKVSVPSNLSYGEWLHGFEKKAKECMAGTSGSEEVKVLE 1090
Query: 646 KQLKDDDKLMLLLEI 660
+LK+ D++ LL++
Sbjct: 1091 HKLKEADEMHTLLQL 1105
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 43.1 bits (100), Expect = 0.001
Identities = 106/474 (22%), Positives = 196/474 (41%), Gaps = 79/474 (16%)
Query: 30 LEIKTRSVEQTLLPLVSQITTLINHKDNTKKSDKTLQAIQRVGQA-VNLAVGRFVKVGEA 88
L++K +E+ L V+ T L + D TK+ + QA+Q+ A + A +V
Sbjct: 458 LQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQ 517
Query: 89 IANENWDL--------KEEINIACIEAK--------QAGE-TIAALTDITNLNHLESDGQ 131
I +++ + K + NI+ +E + QAGE A L + NH + Q
Sbjct: 518 IGDKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQE-Q 576
Query: 132 ITIFTDKTGVIKAARLLLSSVTKVLLLADRVVIKQIITSRNKVLATMERLEKVNSFQEFV 191
+T T+K L + ++ A + Q+ + + A +R V S + V
Sbjct: 577 VTQLTEK----------LKNQSESHKQAQENLHDQVQEQKAHLRAAQDR---VLSLETSV 623
Query: 192 QIFSQFGNEMVEFAHLSGDRQNDLKDEKKKAKMAAARAVLEKCTMMLLTASKTCLRH--P 249
+ NE E Q D++ + K + +A A TA + L++
Sbjct: 624 NELNSQLNESKEKV-----SQLDIQIKAKTELLLSAEAA--------KTAQRADLQNHLD 670
Query: 250 NCESAHKNKEGVFDRMKVALDKVIEIVTDCKPNGETDISSISIFTGIKEFKMNIEALREN 309
++A ++K+ +++ LD+V + D + + S + + KE +++E E
Sbjct: 671 TAQNALQDKQQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEY---KEKYLSLEQKTEE 727
Query: 310 LYFQSKENLSVTLEVILER---MEDFTDSAYTSHEHRERILELSTQARMELQQLISVWIQ 366
L Q K+ + +LEV + ++D + + R ELS Q ME + + S +
Sbjct: 728 LEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLD 787
Query: 367 AQSK-------KTKSIAEELELSIL-----------KISHSLNELKKELHSTATQLAADL 408
Q K K K +E E IL KI H EL + +T T+L
Sbjct: 788 LQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQH--EELNNRIQTTVTELQKVK 845
Query: 409 LKYHADHVVLKAL--KLTGVEGNLE-ALAEYACKLSEQKEQLVE---TCRLLRH 456
++ A L + KL+ V +L+ + +E+ + + K +++ TC+ L+H
Sbjct: 846 MEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKH 899
Score = 35.0 bits (79), Expect = 0.25
Identities = 73/369 (19%), Positives = 144/369 (39%), Gaps = 53/369 (14%)
Query: 258 KEGVFDRMKVALDKVIEIVTDCKPNGETDISS---------ISIFTGIKEFKMNIEALRE 308
KE + + DK+ + V+D N +++ + + KE K ++ E
Sbjct: 848 KEALMTELSTVKDKLSK-VSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQME 906
Query: 309 NLYFQSKENLSVTLEVILERMEDFTDSAYTSHEH---RERILELSTQARMELQQLISVWI 365
N + KE L +LE E + E + L+ + + +LQ I+
Sbjct: 907 NTLKEQKE-LKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELK 965
Query: 366 QAQSKKTKSIAE---ELELSILKISHSLNELKKELHSTATQLAADLLKYHADHVVLKALK 422
Q+ +K K I EL++++L+ + N+L+++L A +LAA+ K ++
Sbjct: 966 QSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKI--------SVL 1017
Query: 423 LTGVEGNLEALAEYACKLSEQKEQLVETCRLLRHISGTEPLEITCIHAEETFQVTGQQII 482
E + E + ++ +L+ T + L+ + EE + + +I
Sbjct: 1018 QNNYEKSQETFKQLQSDFYGRESELLATRQDLKSV-------------EEKLSLAQEDLI 1064
Query: 483 SAAETL----TLHPSSKIAKENLDVFCEAWESQISDMSTLLREINDVFEGRRGEKYGYLS 538
S + L K AK L+ E Q+ + L++I + EK S
Sbjct: 1065 SNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQLQERCKALQDI-------QKEK----S 1113
Query: 539 LPKPMKNNANLKSLKPDKPDSEEQAKIAKLGLKLGLLTSDADCEIEKWEDQENEIVQYGR 598
L + N K + ++ ++ +I KL +L ++ EI +D + ++Q
Sbjct: 1114 LKEKELVNEKSKLAEIEEIKCRQEKEITKLNEELKSHKLESIKEITNLKDAKQLLIQQKL 1173
Query: 599 NMSSMAYSL 607
+ A SL
Sbjct: 1174 ELQGKADSL 1182
>gi|4504063 golgin 97 [Homo sapiens]
Length = 767
Score = 41.6 bits (96), Expect = 0.003
Identities = 114/570 (20%), Positives = 215/570 (37%), Gaps = 101/570 (17%)
Query: 162 VVIKQIITSRNKVLATMERLEKVNSFQEFVQIFSQFGNEMVEFAHLSGDRQNDLKDEKKK 221
++ Q+ +N+ + +R ++++ + F Q E+ + H+ LK E+
Sbjct: 148 ILTAQLQEMKNQSMNLFQRRDEMDELEGFQQ------QELSKIKHML------LKKEESL 195
Query: 222 AKMAAARAVLEKCTMMLLTASKTCLRHPNCESAHKNKEGVFDRMKVALDKVIEIVTDCKP 281
KM LE T L + + S K R L++ + V K
Sbjct: 196 GKMEQE---LEARTRELSRTQEELMNSNQMSSDLSQKLEELQRHYSTLEEQRDHVIASKT 252
Query: 282 NGETDISSISIFTGIKEFKMNIEALRENLYF---------QSKENLSVTLEVILERMEDF 332
E+ I T +++ + ++AL + L Q KE++ L+ + +E
Sbjct: 253 GAESKI------TALEQKEQELQALIQQLSIDLQKVTAETQEKEDVITHLQEKVASLEKR 306
Query: 333 TDSAYTSHEHRERILELSTQARMELQQLISVWIQAQSKKTKSIAEELELSILKISHSLNE 392
+ + EH + +L+ T A L+ + A+S + K+I LE + ++ +L
Sbjct: 307 LEQNLSGEEHVQELLKEKTLAEQNLEDTRQQLLAARSSQAKAI-NTLETRVRELEQTLQA 365
Query: 393 LKKELHSTATQLAAD--------LLKYHADHVVLKALKL--------TGVEGNLEAL--- 433
+++L + +AA + HV +AL L +E + AL
Sbjct: 366 SEEQLQQSKGIVAAQETQIQELAAANQESSHVQQQALALEQQFLERTQALEAQIVALERT 425
Query: 434 -------AEYACKLSEQKEQLVETCR------LLRHISGTEPLEITCIHAEETFQVTGQQ 480
AE + EQ+ ++ CR L H + L+ EE Q ++
Sbjct: 426 RAADQTTAEQGMRQLEQENAALKECRNEYERSLQNHQFELKKLK------EEWSQ---RE 476
Query: 481 IISAAETLTLHPSSKIAKE------NLDVFCEAWESQISDMS-TLLREINDVFEGRRGEK 533
I+S A L K +E NL + E + + + LL++ ++ + RG
Sbjct: 477 IVSVAMAQALEEVRKQREEFQQQAANLTAIIDEKEQNLREKTEVLLQKEQEILQLERGHN 536
Query: 534 YGYLSLPKPMKNNANLKSLKPDKPDSEEQAKIAKLGLKLGLLTSDADCEIEKWEDQENEI 593
L + + L++LK +EE A +A+ + LL + E E+ +
Sbjct: 537 SALLQIHQLQAELEALRTLK-----AEEAAVVAE---QEDLLRLRGPLQAEALSVNESHV 588
Query: 594 VQYGRNMSSMAYSLYLFTRGEGPLKTSQDLIHQLEVFAAEGLKLTSSVQAFSKQLKDDDK 653
R M + L T G P EV A + +L Q +QL + +K
Sbjct: 589 T--SRAMQDPVFQLP--TAGRTP---------NGEVGAMDLTQLQKEKQDLEQQLLEKNK 635
Query: 654 LMLLLEINKLIPLCHQLQTVTKTSLQNKVF 683
+ ++ +++ L LQ K N++F
Sbjct: 636 TIKQMQ-QRMLELRKTLQKELKIRPDNELF 664
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 40.8 bits (94), Expect = 0.005
Identities = 101/504 (20%), Positives = 201/504 (39%), Gaps = 89/504 (17%)
Query: 218 EKKKAKMAAARAVLEKCTMMLLTASKTCLRHPNCES-----AHKNKEGVFDRMKVALDKV 272
E K + A L++ T+ LT K L+ + ++ A ++K + K+ L++
Sbjct: 976 ENKVKNLTEEMAGLDE-TIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQ 1034
Query: 273 IEIVTDCKPNGETDISSISIFTGIKEFKMNIEALRENLYFQSKENLSVTLEVILERMEDF 332
++ D + + E + K+ +M++E ++K L L++ E D
Sbjct: 1035 VD---DLEGSLEQE----------KKIRMDLE--------RAKRKLEGDLKLAQESTMDI 1073
Query: 333 -TDSAYTSHEHRERILELS-TQARMELQQLISVWIQAQSKKTKSIAEELELSI------- 383
D + +++ E+S Q+++E +Q + + +Q + K+ ++ EELE I
Sbjct: 1074 ENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASR 1133
Query: 384 -------LKISHSLNELKKELHSTATQLAADLLKYHADHVVLKALKLTGVEGNLEALAEY 436
+S L E+ + L +A + + ++ E L+ A
Sbjct: 1134 AKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATA 1193
Query: 437 ACKLSEQKEQLVETCRLLRHISGTEPLEITCIHAEETFQVTGQQIISAAETLTLHPSSKI 496
A + + + E L I + ++ + ++ + S ET++
Sbjct: 1194 ATLRKKHADSVAE---LGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSK------ 1244
Query: 497 AKENLDVFCEAWESQISDMSTLLRE----INDVF--EGRRGEKYGYLSLPKPMKN----- 545
AK NL+ C A E Q+S++ T E IND+ R + G S K+
Sbjct: 1245 AKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQ 1304
Query: 546 -----NANLKSLKPDKPDSEEQAKIAKLGLKLGLLTSDADCEI--EKWEDQENEIVQYGR 598
A + ++ K EE+ K AK L L +S DC++ E++E+++ + R
Sbjct: 1305 LSRGKQAFTQQIEELKRQLEEEIK-AKSALAHALQSSRHDCDLLREQYEEEQEAKAELQR 1363
Query: 599 NMSSMAYSLYLFTRGEGPLKTSQDLIHQLEVFAAEGLKLTSSVQAFSKQLKDDDKLMLLL 658
MS + + K D I + E +L + + +++L+D ++
Sbjct: 1364 AMSKANSEV-----AQWRTKYETDAIQRTE-------ELEEAKKKLAQRLQDAEE----- 1406
Query: 659 EINKLIPLCHQLQTVTKTSLQNKV 682
+ + C L+ TK LQN+V
Sbjct: 1407 HVEAVNAKCASLEK-TKQRLQNEV 1429
Score = 30.4 bits (67), Expect = 6.1
Identities = 47/245 (19%), Positives = 95/245 (38%), Gaps = 30/245 (12%)
Query: 371 KTKSIAEELELSILKISHSLNELKKELHSTATQLAADLLKYHADHVVLKAL----KLTGV 426
KT++ +ELE ++ + N+L+ ++ + A LA + D ++ + K+ V
Sbjct: 869 KTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLAD--AEERCDQLIKTKIQLEAKIKEV 926
Query: 427 EGNLEALAEYACKLSEQKEQLVETCRLLRHISGTEPLEITCIHAEETFQVTGQQIISAAE 486
E E +L+ +K +L + C L+ + LE+T E+ T ++ + E
Sbjct: 927 TERAEDEEEINAELTAKKRKLEDECSELK--KDIDDLELTLAKVEKEKHATENKVKNLTE 984
Query: 487 TLT--LHPSSKIAKENLDVFCEAWESQISDMSTLLREINDVFEGRRGEKYGYLSLPKPMK 544
+ +K+ KE EA + + D+ ++N + K
Sbjct: 985 EMAGLDETIAKLTKEK-KALQEAHQQTLDDLQAEEDKVNTL-----------------TK 1026
Query: 545 NNANLKSLKPDKPDSEEQAKIAKLGLKLGLLTSDADCEI--EKWEDQENEIVQYGRNMSS 602
L+ D S EQ K ++ L+ + D ++ E D EN+ Q +
Sbjct: 1027 AKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKK 1086
Query: 603 MAYSL 607
+ +
Sbjct: 1087 KEFEM 1091
Score = 30.4 bits (67), Expect = 6.1
Identities = 33/144 (22%), Positives = 60/144 (41%), Gaps = 8/144 (5%)
Query: 385 KISHSLNELKKELHSTATQLAADLLKYHADHVVLKALKLTGVEGNLEALAEYACKLSEQK 444
K+ LNE++ +L+ A L Y +LK +L +L+ L EQ
Sbjct: 1621 KMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQL-----HLDDALRSQEDLKEQL 1675
Query: 445 EQLVETCRLLRHISGTEPLEITCIHAEETFQVTGQQIISAAETLTLHPSSKIAKENLDVF 504
+ LL+ + E L T E + ++ Q+++ A+E + L + + N
Sbjct: 1676 AMVERRANLLQ--AEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKK 1733
Query: 505 CEAWESQI-SDMSTLLREINDVFE 527
E SQI +M +++E + E
Sbjct: 1734 LETDISQIQGEMEDIIQEARNAEE 1757
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 40.8 bits (94), Expect = 0.005
Identities = 92/471 (19%), Positives = 185/471 (39%), Gaps = 76/471 (16%)
Query: 218 EKKKAKMAAARAVLEKCTMMLLTASKTCLRHPNCES-----AHKNKEGVFDRMKVALDKV 272
E K + A L++ T+ LT K L+ + ++ A ++K + K+ L++
Sbjct: 978 ENKVKNLTEEMAGLDE-TIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQ 1036
Query: 273 IEIVTDCKPNGETDISSISIFTGIKEFKMNIEALRENLYFQSKENLSVTLEVILERMEDF 332
++ D + + E + K+ +M++E ++K L L++ E + D
Sbjct: 1037 VD---DLEGSLEQE----------KKLRMDLE--------RAKRKLEGDLKLAQESIMDI 1075
Query: 333 TDSAYTSHEH-RERILELST-QARMELQQLISVWIQAQSKKTKSIAEELELSI------- 383
+ E +++ E+S Q+++E +Q + + +Q + K+ ++ EELE I
Sbjct: 1076 ENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASR 1135
Query: 384 -------LKISHSLNELKKELHSTATQLAADLLKYHADHVVLKALKLTGVEGNLEALAEY 436
+S L E+ + L +A + + ++ E L+ A
Sbjct: 1136 AKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATA 1195
Query: 437 ACKLSEQKEQLVETCRLLRHISGTEPLEITCIHAEETFQVTGQQIISAAETLTLHPSSKI 496
A + + + E L I + ++ + ++ + S ET++
Sbjct: 1196 ATLRKKHADSVAE---LGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSK------ 1246
Query: 497 AKENLDVFCEAWESQISDMSTLLRE----INDVF--EGRRGEKYGYLSLPKPMK------ 544
AK NL+ C E Q+S++ + E IND+ GR + G S K
Sbjct: 1247 AKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQ 1306
Query: 545 ----NNANLKSLKPDKPDSEEQAKIAKLGLKLGLLTSDADCEI--EKWEDQENEIVQYGR 598
A + ++ K EE+ K AK L L +S DC++ E++E+++ + R
Sbjct: 1307 LSRGKQAFTQQIEELKRQLEEEIK-AKNALAHALQSSRHDCDLLREQYEEEQESKAELQR 1365
Query: 599 NMSSMAYSLYLFTRGEGPLKTSQDLIHQLEVFAAEGLKLTSSVQAFSKQLK 649
+S + + K D I + E KL +QA + ++
Sbjct: 1366 ALSKANTEV-----AQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVE 1411
Score = 30.0 bits (66), Expect = 8.0
Identities = 113/578 (19%), Positives = 211/578 (36%), Gaps = 65/578 (11%)
Query: 59 KKSDKTLQAIQRVGQAVNLAVGRFVKVGEAIANENWDLK---EEINIAC--IEAKQAG-- 111
KK + LQA + +AVN K + + NE DL E N AC ++ KQ
Sbjct: 1397 KKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFD 1456
Query: 112 ETIAALTDITNLNHLESDGQITIFTDKTGVIKAARLLLSSVTKVLLLADRVVIK-QIITS 170
+ +A H E + K AR L + + K+ + + + + +
Sbjct: 1457 KILAEWKQKCEETHAELEAS----------QKEARSLGTELFKIKNAYEESLDQLETLKR 1506
Query: 171 RNKVL------ATMERLEKVNSFQEFVQIFSQFGNEMVEFAHLSGDRQNDLKDEKKKAKM 224
NK L T + E E +I Q E E + + L+ E+ K
Sbjct: 1507 ENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGK--- 1563
Query: 225 AAARAVLEKCTMMLLTASKTCLRHPNCESAHKNKEGVFDRMKVALDKVIEIVTDC---KP 281
R LE + K + + +N + + M+ LD I D K
Sbjct: 1564 -ILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKK 1622
Query: 282 NGETDISSISIFTGIKEFKMNIEALRENLYFQSKENLSVTLEVILERMEDFTDSAYTSHE 341
E D++ + I +M EALR N T ++ + D+ + +
Sbjct: 1623 KMEGDLNEMEIQLNHAN-RMAAEALR---------NYRNTQGILKDTQIHLDDALRSQED 1672
Query: 342 HRERILELSTQARM---ELQQLISVWIQAQSKKTKSIAEELELSILKISHSLNELKKELH 398
+E++ + +A + E+++L + Q+++++ IAE+ L + L+ L
Sbjct: 1673 LKEQLAMVERRANLLQAEIEELRAT--LEQTERSRKIAEQELLDASERVQLLHTQNTSLI 1730
Query: 399 STATQLAADLLKYHADHVVLKALKLTGVEGNLEALAEYACKLSEQKEQLVETCRLLRHIS 458
+T +L D+ + + + E +A+ + A E K++ + L R
Sbjct: 1731 NTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKK 1790
Query: 459 GTE----PLEITCIHAEETFQVTGQQIISAAETLTLHPSSKIAKENLDVFCEAWESQISD 514
E L++ AE+ G++ I E ++ E + +
Sbjct: 1791 NMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQ-----KRNAEAVKG 1845
Query: 515 MSTLLREINDVFEGRRGEKYGYLSLPKPM-KNNANLKSLKPDKPDSEEQ-----AKIAKL 568
+ R + ++ ++ L L + K A +KS K ++EEQ AK KL
Sbjct: 1846 LRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKL 1905
Query: 569 GLKLGLLTSDADCEIEKWEDQENEIVQYGRNMSSMAYS 606
+L +A+ + E Q N++ R + + S
Sbjct: 1906 QHEL----EEAEERADIAESQVNKLRVKSREVHTKVIS 1939
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 40.8 bits (94), Expect = 0.005
Identities = 92/471 (19%), Positives = 185/471 (39%), Gaps = 76/471 (16%)
Query: 218 EKKKAKMAAARAVLEKCTMMLLTASKTCLRHPNCES-----AHKNKEGVFDRMKVALDKV 272
E K + A L++ T+ LT K L+ + ++ A ++K + K+ L++
Sbjct: 978 ENKVKNLTEEMAGLDE-TIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQ 1036
Query: 273 IEIVTDCKPNGETDISSISIFTGIKEFKMNIEALRENLYFQSKENLSVTLEVILERMEDF 332
++ D + + E + K+ +M++E ++K L L++ E + D
Sbjct: 1037 VD---DLEGSLEQE----------KKLRMDLE--------RAKRKLEGDLKLAQESIMDI 1075
Query: 333 TDSAYTSHEH-RERILELST-QARMELQQLISVWIQAQSKKTKSIAEELELSI------- 383
+ E +++ E+S Q+++E +Q + + +Q + K+ ++ EELE I
Sbjct: 1076 ENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASR 1135
Query: 384 -------LKISHSLNELKKELHSTATQLAADLLKYHADHVVLKALKLTGVEGNLEALAEY 436
+S L E+ + L +A + + ++ E L+ A
Sbjct: 1136 AKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATA 1195
Query: 437 ACKLSEQKEQLVETCRLLRHISGTEPLEITCIHAEETFQVTGQQIISAAETLTLHPSSKI 496
A + + + E L I + ++ + ++ + S ET++
Sbjct: 1196 ATLRKKHADSVAE---LGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSK------ 1246
Query: 497 AKENLDVFCEAWESQISDMSTLLRE----INDVF--EGRRGEKYGYLSLPKPMK------ 544
AK NL+ C E Q+S++ + E IND+ GR + G S K
Sbjct: 1247 AKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQ 1306
Query: 545 ----NNANLKSLKPDKPDSEEQAKIAKLGLKLGLLTSDADCEI--EKWEDQENEIVQYGR 598
A + ++ K EE+ K AK L L +S DC++ E++E+++ + R
Sbjct: 1307 LSRGKQAFTQQIEELKRQLEEEIK-AKNALAHALQSSRHDCDLLREQYEEEQESKAELQR 1365
Query: 599 NMSSMAYSLYLFTRGEGPLKTSQDLIHQLEVFAAEGLKLTSSVQAFSKQLK 649
+S + + K D I + E KL +QA + ++
Sbjct: 1366 ALSKANTEV-----AQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVE 1411
Score = 30.0 bits (66), Expect = 8.0
Identities = 113/578 (19%), Positives = 211/578 (36%), Gaps = 65/578 (11%)
Query: 59 KKSDKTLQAIQRVGQAVNLAVGRFVKVGEAIANENWDLK---EEINIAC--IEAKQAG-- 111
KK + LQA + +AVN K + + NE DL E N AC ++ KQ
Sbjct: 1397 KKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFD 1456
Query: 112 ETIAALTDITNLNHLESDGQITIFTDKTGVIKAARLLLSSVTKVLLLADRVVIK-QIITS 170
+ +A H E + K AR L + + K+ + + + + +
Sbjct: 1457 KILAEWKQKCEETHAELEAS----------QKEARSLGTELFKIKNAYEESLDQLETLKR 1506
Query: 171 RNKVL------ATMERLEKVNSFQEFVQIFSQFGNEMVEFAHLSGDRQNDLKDEKKKAKM 224
NK L T + E E +I Q E E + + L+ E+ K
Sbjct: 1507 ENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGK--- 1563
Query: 225 AAARAVLEKCTMMLLTASKTCLRHPNCESAHKNKEGVFDRMKVALDKVIEIVTDC---KP 281
R LE + K + + +N + + M+ LD I D K
Sbjct: 1564 -ILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKK 1622
Query: 282 NGETDISSISIFTGIKEFKMNIEALRENLYFQSKENLSVTLEVILERMEDFTDSAYTSHE 341
E D++ + I +M EALR N T ++ + D+ + +
Sbjct: 1623 KMEGDLNEMEIQLNHAN-RMAAEALR---------NYRNTQGILKDTQIHLDDALRSQED 1672
Query: 342 HRERILELSTQARM---ELQQLISVWIQAQSKKTKSIAEELELSILKISHSLNELKKELH 398
+E++ + +A + E+++L + Q+++++ IAE+ L + L+ L
Sbjct: 1673 LKEQLAMVERRANLLQAEIEELRAT--LEQTERSRKIAEQELLDASERVQLLHTQNTSLI 1730
Query: 399 STATQLAADLLKYHADHVVLKALKLTGVEGNLEALAEYACKLSEQKEQLVETCRLLRHIS 458
+T +L D+ + + + E +A+ + A E K++ + L R
Sbjct: 1731 NTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKK 1790
Query: 459 GTE----PLEITCIHAEETFQVTGQQIISAAETLTLHPSSKIAKENLDVFCEAWESQISD 514
E L++ AE+ G++ I E ++ E + +
Sbjct: 1791 NMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQ-----KRNAEAVKG 1845
Query: 515 MSTLLREINDVFEGRRGEKYGYLSLPKPM-KNNANLKSLKPDKPDSEEQ-----AKIAKL 568
+ R + ++ ++ L L + K A +KS K ++EEQ AK KL
Sbjct: 1846 LRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKL 1905
Query: 569 GLKLGLLTSDADCEIEKWEDQENEIVQYGRNMSSMAYS 606
+L +A+ + E Q N++ R + + S
Sbjct: 1906 QHEL----EEAEERADIAESQVNKLRVKSREVHTKVIS 1939
>gi|109255234 centrosomal protein 290kDa [Homo sapiens]
Length = 2479
Score = 40.4 bits (93), Expect = 0.006
Identities = 123/614 (20%), Positives = 228/614 (37%), Gaps = 107/614 (17%)
Query: 29 GLEIKTRSVEQTLLPLVSQITTLINHKDNTKKSDKTLQAIQR--------VGQAVNLAVG 80
G+ K + E + L Q+ TL KD K+DK +QR V Q + +
Sbjct: 1924 GIRNKLKEKEGEVFTLTKQLNTL---KDLFAKADKEKLTLQRKLKTTGMTVDQVLGIRAL 1980
Query: 81 RFVKVGEAIANENWDLKEEINIACIEAKQAGETIAALTDI--------TNLNHLESDGQI 132
K E + N DL+ +I + A QA + + D+ L+ LE
Sbjct: 1981 ESEKELEELKKRNLDLENDI--LYMRAHQALPRDSVVEDLHLQNRYLQEKLHALEKQFSK 2038
Query: 133 TIFTDKT--GVIK---AARLLLSSVTKVLLLADRVVIKQIITSRNKVLATMERLEKVNSF 187
++ + G+ R + L ++ + +K + NK L ++ +V
Sbjct: 2039 DTYSKPSISGIESDDHCQREQELQKENLKLSSENIELKFQLEQANKDLPRLKN--QVRDL 2096
Query: 188 QEFVQIFSQFGNEMV-EFAHLSGDRQNDLKDEKKKAKMAAARAVLEKCTM---MLLTASK 243
+E + + E+ + H+ G ++ + + + + V+EK L AS
Sbjct: 2097 KEMCEFLKKEKAEVQRKLGHVRGSGRSGKTIPELEKTIGLMKKVVEKVQRENEQLKKASG 2156
Query: 244 --TCLRHPNCESAHKNKEGVFDRMKVALDKVIEIVTDCKPNGETDISSISIFTGIKEFKM 301
T + N E ++ + +++K L + + + K G I + +
Sbjct: 2157 ILTSEKMANIEQENEKLKAELEKLKAHLGHQLSMHYESKTKGTEKIIAEN---------- 2206
Query: 302 NIEALRENLYFQSKENLSVTLEVILERMEDFTDSAYTSHEHRERILELSTQARMELQQLI 361
E LR+ L + + + + L + +E + E + L+ + +L+
Sbjct: 2207 --ERLRKEL--KKETDAAEKLRIAKNNLEILNEKMTVQLEETGKRLQFAESRGPQLEG-- 2260
Query: 362 SVWIQAQSKKTKSIA---------EELELSILKISHSLNELKKELHSTATQLAADLLKYH 412
A SK KSI +ELE I K + S+ +LK +L AT+ + KY+
Sbjct: 2261 -----ADSKSWKSIVVTRMYETKLKELETDIAKKNQSITDLK-QLVKEATEREQKVNKYN 2314
Query: 413 AD---------HVVLKALKLTGVEGNLEALAEYACKLSEQKEQLVETCRLLRHISGTEPL 463
D HV A G++ L+ L +L ++K +L+ + SG E
Sbjct: 2315 EDLEQQIKILKHVPEGAETEQGLKRELQVLRLANHQLDKEKAELIHQIEANKDQSGAEST 2374
Query: 464 EITCIHAEETFQVTGQQI-ISAAETLTLHPSSKIAKENLDVFCEAWESQISDMSTLLREI 522
+E + Q+ +S E L K K+ L+ F ++ +I D+
Sbjct: 2375 IPDADQLKEKIKDLETQLKMSDLEKQHLKEEIKKLKKELENFDPSFFEEIEDL------- 2427
Query: 523 NDVFEGRRGEKYGYLSLPKPMKNNANLKSLKPDKPDSEEQAKIAKLGLKLGLLTSDADCE 582
KY Y + +K N L+ K+ KL +LG+ +
Sbjct: 2428 ----------KYNY---KEEVKKNILLEE------------KVKKLSEQLGVELTSPVAA 2462
Query: 583 IEKWEDQENEIVQY 596
E++ED+E V +
Sbjct: 2463 SEEFEDEEESPVNF 2476
Score = 33.5 bits (75), Expect = 0.72
Identities = 100/462 (21%), Positives = 187/462 (40%), Gaps = 86/462 (18%)
Query: 303 IEALRENLYFQSKENLSVTLEVILERMEDFTDSAYTSHEHRERILELSTQ--ARMELQQL 360
+E L+ L + K+ +++ +LE + T +A ERI+ ++Q A + +QQ+
Sbjct: 1727 VERLKSQLALKEKQQKALS-RALLELRAEMTAAA------EERIISATSQKEAHLNVQQI 1779
Query: 361 ISVWIQAQSKKTKSIAEELELSILKISHSLNELKKELHSTATQLAADLLKYHADHVVLKA 420
+ +++ K+ E+L ++LK+ +L K +S L DL ++ + K
Sbjct: 1780 VD----RHTRELKTQVEDLNENLLKLKEALKTSKNRENSLTDNL-NDL-----NNELQK- 1828
Query: 421 LKLTGVEGNLEALAEYACKLSEQKEQLVETCRLLRHISGTEPLEITCIHAEETFQVTGQQ 480
K L E + E K Q+ L+ T+ + + + Q
Sbjct: 1829 -KQKAYNKILREKEEIDQENDELKRQIKRLTSGLQGKPLTDNKQSLIEELQRKVKKLENQ 1887
Query: 481 IISAAETLTLHP-SSKIAKENLDVFCEA--WESQISDMSTLLREINDVFEGRRGEKYGYL 537
+ E + L P K AKE L + E W+++I + L+E + GE +
Sbjct: 1888 LEGKVEEVDLKPMKEKNAKEELIRWEEGKKWQAKIEGIRNKLKE-------KEGEVF--- 1937
Query: 538 SLPKPMKNNANLKSLKPDKPDSEEQAKIAKLGLK----LGLLTSDADCEIEKWE----DQ 589
+L K + +L + K DK Q K+ G+ LG+ +++ E+E+ + D
Sbjct: 1938 TLTKQLNTLKDLFA-KADKEKLTLQRKLKTTGMTVDQVLGIRALESEKELEELKKRNLDL 1996
Query: 590 ENEIVQYGRNMS----SMAYSLYLFTRGEGPLKTSQDLIHQLEVFAAEGLKLTSSVQAFS 645
EN+I+ + + S+ L+L R Q+ +H LE ++ S+
Sbjct: 1997 ENDILYMRAHQALPRDSVVEDLHLQNR------YLQEKLHALEKQFSKDTYSKPSISG-- 2048
Query: 646 KQLKDDDKLMLLLEINK--------LIPLCHQLQTVTK--TSLQNKV--------FLKVD 687
++ DD E+ K I L QL+ K L+N+V FLK +
Sbjct: 2049 --IESDDHCQREQELQKENLKLSSENIELKFQLEQANKDLPRLKNQVRDLKEMCEFLKKE 2106
Query: 688 KCITKTR-----------SMMALLVQLLSLCYKLLKKLQMEN 718
K + + + L + + L K+++K+Q EN
Sbjct: 2107 KAEVQRKLGHVRGSGRSGKTIPELEKTIGLMKKVVEKVQREN 2148
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 40.4 bits (93), Expect = 0.006
Identities = 50/219 (22%), Positives = 94/219 (42%), Gaps = 19/219 (8%)
Query: 29 GLEIKTRSVEQTLLPLVSQITTLINHKDNTKKS-----------DKTLQAIQRVGQAVNL 77
GLE R EQ L Q+ TL + + ++ ++ L+ +R Q
Sbjct: 803 GLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVE 862
Query: 78 AVGRFVKVGEAIANENWDLKEEINIACIEAKQAGETIAALTDITNLNHLESDGQITIFTD 137
A+ R + EA+A E+ L ++ + A++ G T++ L +G +
Sbjct: 863 ALERAAREKEALAKEHAGLAVQL----VAAEREGRTLSEEATRLRLEKEALEGSLFEVQR 918
Query: 138 KTGVIKAARLLLSSVTKVLLLADRVVIKQIITSRNKVLATMER--LEKVNSFQEFVQIFS 195
+ ++A R L + + LLLA + ++ R +++AT E+ L+K Q+ VQ
Sbjct: 919 QLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQEKASLDKELMAQKLVQAER 978
Query: 196 QFGNEMVEFAHLSGDRQNDLKDEKKKA--KMAAARAVLE 232
+ + E + L+ EK+ A ++ A RA L+
Sbjct: 979 EAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQ 1017
Score = 31.6 bits (70), Expect = 2.8
Identities = 93/449 (20%), Positives = 179/449 (39%), Gaps = 66/449 (14%)
Query: 322 LEVILERMEDFTDSAYTSHEHRERIL-------ELSTQARMELQQLISVWIQAQSKKTKS 374
LE L+R+ D TD A +HE +R + EL ++ + L + V Q Q+++ +
Sbjct: 566 LEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHSLQV-AQQQAEELRQ 624
Query: 375 IAEELELSILKISHSLNELKKELHSTATQLAADLLKYHADHVVLKAL--KLTGVEGNLEA 432
E+L+ + ++ + L++E A + H L+ L K + + L
Sbjct: 625 EREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVE 684
Query: 433 LAEYACKLSEQKEQL-VETCRLLRHISGTE------PLEITCIHAEETFQVTGQQIISAA 485
+ E + + Q++ L E + ++ E L +T + AEE +SA
Sbjct: 685 VREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSAL 744
Query: 486 ETLTLHPSSKIAKENLDV------------FCEAWESQISDMSTLLREINDVFEGRRGEK 533
+ +A++ LD+ + + Q +T+ RE + E R E+
Sbjct: 745 -------NESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQ 797
Query: 534 -------YGYLSLPKPMKN--NANLKSLKPDKPDSEEQAKIAKLGLKLG-------LLTS 577
G L + + + L +L+ ++ +EQ +A+L +L
Sbjct: 798 EVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQ--LAQLSRQLSGREQELEQARR 855
Query: 578 DADCEIEKWEDQENEIVQYGRNMSSMAYSLYLFTRGEGPLKTSQDLIHQLEVFAAEG--- 634
+A ++E E E + + +A L R EG + + +LE A EG
Sbjct: 856 EAQRQVEALERAAREKEALAKEHAGLAVQLVAAER-EGRTLSEEATRLRLEKEALEGSLF 914
Query: 635 --LKLTSSVQAFSKQLKDDDKLMLLLE---INKLIPLCHQ-LQTVTKTSLQNKVFLKVDK 688
+ + ++A +QL+ + + +LL + +L L Q + T K SL + L K
Sbjct: 915 EVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQEKASLDKE--LMAQK 972
Query: 689 CITKTRSMMALLVQLLSLCYKLLKKLQME 717
+ R A L + + + L++LQ E
Sbjct: 973 LVQAEREAQASLREQRAAHEEDLQRLQRE 1001
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 40.0 bits (92), Expect = 0.008
Identities = 65/342 (19%), Positives = 139/342 (40%), Gaps = 29/342 (8%)
Query: 315 KENLSVTLEVILERMEDFTDSAYTSHEHRERILE--LSTQARMELQQLISVWIQAQSKKT 372
K+ L L + R+E+ D R+++ + L + ++E ++ +Q +
Sbjct: 917 KQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTA 976
Query: 373 KSIAEELELSILKISHSLNELKKE---LHSTATQLAADLLKYHADHVVLKALKLTGVEGN 429
++ ++LE IL + N+L KE L + L +L + KA LT ++
Sbjct: 977 EAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEE-----KAKNLTKLKNK 1031
Query: 430 LEAL-AEYACKLSEQKEQLVETCRLLRHISGTEPLEITCIHAEETFQVTGQQIISAAETL 488
E++ +E +L ++++ E +L R + G + + H Q+ Q A+
Sbjct: 1032 HESMISELEVRLKKEEKSRQELEKLKRKLEG----DASDFHE----QIADLQ----AQIA 1079
Query: 489 TLHPSSKIAKENLDVFCEAWESQISDMSTLLREINDVFEGRRGEKYGYLSLPKPMKNNAN 548
L +E L + +I+ + L++I ++ EG + L + +N A
Sbjct: 1080 ELKMQLAKKEEELQAALARLDDEIAQKNNALKKIREL-EGHISDLQEDLDSERAARNKA- 1137
Query: 549 LKSLKPDKPDSEEQAKIAKLGLKLGLLTSDADCEIEKWEDQENEIVQYGRNMSSMAYSLY 608
+ K D E+ + K L+ L ++ E+ +QE +++ + + ++
Sbjct: 1138 ----EKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQ 1193
Query: 609 LFTRGEGPLKTSQDLIHQLEVFAAEGLKLTSSVQAFSKQLKD 650
+ + + ++L QLE F L + Q K+ D
Sbjct: 1194 VQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENAD 1235
Score = 36.2 bits (82), Expect = 0.11
Identities = 109/570 (19%), Positives = 227/570 (39%), Gaps = 79/570 (13%)
Query: 165 KQIITSRNKVLATMERLEKV-NSFQEFVQIFSQFGNEM-VEFAHLSGDRQNDLKDEKKKA 222
+++ +++ T ER +K N +E Q SQ E + L + + + E+ +
Sbjct: 852 EEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRV 911
Query: 223 KMAAARAVLEKCTMMLLTASKTCLRHPNCESAHKNKEGVFDRMKVA---LDKVIEIVTDC 279
++AA + LE+ +L + L E + ++ +R K+A LD ++ +
Sbjct: 912 RLAAKKQELEE----ILHEMEARLE----EEEDRGQQLQAERKKMAQQMLDLEEQLEEEE 963
Query: 280 KPNGETDISSISIFTGIKEFKMNIEALRENLYFQSKENLSVTLEVILERMEDFTDSAYTS 339
+ + ++ IK+ + I + + SKE +++ ER+ D T +
Sbjct: 964 AARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKER-----KLLEERISDLTTNLAEE 1018
Query: 340 HEHRERILELST---------QARMELQQLISVWIQAQSKKTKSIAEELELSILKISHSL 390
E + + +L + R++ ++ ++ +K + A + I + +
Sbjct: 1019 EEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQI 1078
Query: 391 NELKKELHSTATQLAADLLKYHADHVVLK---ALKLTGVEGNLEALAEYACKLSEQKEQL 447
ELK +L +L A L + D + K K+ +EG++ L E L ++
Sbjct: 1079 AELKMQLAKKEEELQAALARLD-DEIAQKNNALKKIRELEGHISDLQE---DLDSERAAR 1134
Query: 448 VETCRLLRHISGTEPLEITCIHAEETFQVTGQQIISAAETLTLHPSSKIAKENLDVFCEA 507
+ + R + E LE E+T T Q A+ + K+ LD +
Sbjct: 1135 NKAEKQKRDLG--EELEALKTELEDTLDSTATQQELRAKR---EQEVTVLKKALDEETRS 1189
Query: 508 WESQISDMSTL-LREINDVFEGRRGEKYGYLSLPKPMKNNANLKSLKPDKPDSEEQAKIA 566
E+Q+ +M + + ++ E K +L K N ++L+ + D + ++
Sbjct: 1190 HEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDK------NKQTLEKENADLAGELRV- 1242
Query: 567 KLGLKLGLLTSDADCEIEKWEDQENEIVQYGRNMSSMAYSLYLFTRGEGPLKTSQDLIHQ 626
LG + + + +K E Q E+ + GE D +H+
Sbjct: 1243 -----LGQAKQEVEHKKKKLEAQVQELQSKCSD-------------GERARAELNDKVHK 1284
Query: 627 LE---------VFAAEG--LKLTSSVQAFSKQLKDDDKLMLLLEINKLIPLCHQLQTV-- 673
L+ + AEG +KL V + S QL+D +L L E + + + +L+ +
Sbjct: 1285 LQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQEL-LQEETRQKLNVSTKLRQLEE 1343
Query: 674 TKTSLQNKVFLKVDKCITKTRSMMALLVQL 703
+ SLQ+++ +++ R + L +QL
Sbjct: 1344 ERNSLQDQLDEEMEAKQNLERHISTLNIQL 1373
Score = 35.4 bits (80), Expect = 0.19
Identities = 56/256 (21%), Positives = 106/256 (41%), Gaps = 39/256 (15%)
Query: 326 LERMEDFTDSAYTSHEHRERILELSTQARMELQQLISVWIQAQSK---KTKSIAEELELS 382
LE D + + + E+ + M+LQ+ ++ +A+ + + + +AEEL S
Sbjct: 1661 LEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASS 1720
Query: 383 ILKISHSLNELKKELHSTATQLAADLLKYHADHVVLKALKLTGVEGNLEALAEYACKLSE 442
L ++L + K+ L + QL +L + +GN+EA+++ K ++
Sbjct: 1721 -LSGRNALQDEKRRLEARIAQLEEELEEE---------------QGNMEAMSDRVRKATQ 1764
Query: 443 QKEQL-----VETCRLLRHISGTEPLEITCIHAEETFQVTGQQIISAAETLTLHPSSKIA 497
Q EQL E ++ S + LE + S ++ +KIA
Sbjct: 1765 QAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIA 1824
Query: 498 KENLDVFCEAWESQISDMS---------TLLREINDVFEGRRGEKYGYLSLPKPMKNNAN 548
+ V EA E Q + S +L ++ D E + E+Y + K NA
Sbjct: 1825 QLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVED--ERKMAEQY----KEQAEKGNAR 1878
Query: 549 LKSLKPDKPDSEEQAK 564
+K LK ++EE+++
Sbjct: 1879 VKQLKRQLEEAEEESQ 1894
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 40.0 bits (92), Expect = 0.008
Identities = 65/342 (19%), Positives = 139/342 (40%), Gaps = 29/342 (8%)
Query: 315 KENLSVTLEVILERMEDFTDSAYTSHEHRERILE--LSTQARMELQQLISVWIQAQSKKT 372
K+ L L + R+E+ D R+++ + L + ++E ++ +Q +
Sbjct: 924 KQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTA 983
Query: 373 KSIAEELELSILKISHSLNELKKE---LHSTATQLAADLLKYHADHVVLKALKLTGVEGN 429
++ ++LE IL + N+L KE L + L +L + KA LT ++
Sbjct: 984 EAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEE-----KAKNLTKLKNK 1038
Query: 430 LEAL-AEYACKLSEQKEQLVETCRLLRHISGTEPLEITCIHAEETFQVTGQQIISAAETL 488
E++ +E +L ++++ E +L R + G + + H Q+ Q A+
Sbjct: 1039 HESMISELEVRLKKEEKSRQELEKLKRKLEG----DASDFHE----QIADLQ----AQIA 1086
Query: 489 TLHPSSKIAKENLDVFCEAWESQISDMSTLLREINDVFEGRRGEKYGYLSLPKPMKNNAN 548
L +E L + +I+ + L++I ++ EG + L + +N A
Sbjct: 1087 ELKMQLAKKEEELQAALARLDDEIAQKNNALKKIREL-EGHISDLQEDLDSERAARNKA- 1144
Query: 549 LKSLKPDKPDSEEQAKIAKLGLKLGLLTSDADCEIEKWEDQENEIVQYGRNMSSMAYSLY 608
+ K D E+ + K L+ L ++ E+ +QE +++ + + ++
Sbjct: 1145 ----EKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQ 1200
Query: 609 LFTRGEGPLKTSQDLIHQLEVFAAEGLKLTSSVQAFSKQLKD 650
+ + + ++L QLE F L + Q K+ D
Sbjct: 1201 VQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENAD 1242
Score = 36.2 bits (82), Expect = 0.11
Identities = 109/570 (19%), Positives = 227/570 (39%), Gaps = 79/570 (13%)
Query: 165 KQIITSRNKVLATMERLEKV-NSFQEFVQIFSQFGNEM-VEFAHLSGDRQNDLKDEKKKA 222
+++ +++ T ER +K N +E Q SQ E + L + + + E+ +
Sbjct: 859 EEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRV 918
Query: 223 KMAAARAVLEKCTMMLLTASKTCLRHPNCESAHKNKEGVFDRMKVA---LDKVIEIVTDC 279
++AA + LE+ +L + L E + ++ +R K+A LD ++ +
Sbjct: 919 RLAAKKQELEE----ILHEMEARLE----EEEDRGQQLQAERKKMAQQMLDLEEQLEEEE 970
Query: 280 KPNGETDISSISIFTGIKEFKMNIEALRENLYFQSKENLSVTLEVILERMEDFTDSAYTS 339
+ + ++ IK+ + I + + SKE +++ ER+ D T +
Sbjct: 971 AARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKER-----KLLEERISDLTTNLAEE 1025
Query: 340 HEHRERILELST---------QARMELQQLISVWIQAQSKKTKSIAEELELSILKISHSL 390
E + + +L + R++ ++ ++ +K + A + I + +
Sbjct: 1026 EEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQI 1085
Query: 391 NELKKELHSTATQLAADLLKYHADHVVLK---ALKLTGVEGNLEALAEYACKLSEQKEQL 447
ELK +L +L A L + D + K K+ +EG++ L E L ++
Sbjct: 1086 AELKMQLAKKEEELQAALARLD-DEIAQKNNALKKIRELEGHISDLQE---DLDSERAAR 1141
Query: 448 VETCRLLRHISGTEPLEITCIHAEETFQVTGQQIISAAETLTLHPSSKIAKENLDVFCEA 507
+ + R + E LE E+T T Q A+ + K+ LD +
Sbjct: 1142 NKAEKQKRDLG--EELEALKTELEDTLDSTATQQELRAKR---EQEVTVLKKALDEETRS 1196
Query: 508 WESQISDMSTL-LREINDVFEGRRGEKYGYLSLPKPMKNNANLKSLKPDKPDSEEQAKIA 566
E+Q+ +M + + ++ E K +L K N ++L+ + D + ++
Sbjct: 1197 HEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDK------NKQTLEKENADLAGELRV- 1249
Query: 567 KLGLKLGLLTSDADCEIEKWEDQENEIVQYGRNMSSMAYSLYLFTRGEGPLKTSQDLIHQ 626
LG + + + +K E Q E+ + GE D +H+
Sbjct: 1250 -----LGQAKQEVEHKKKKLEAQVQELQSKCSD-------------GERARAELNDKVHK 1291
Query: 627 LE---------VFAAEG--LKLTSSVQAFSKQLKDDDKLMLLLEINKLIPLCHQLQTV-- 673
L+ + AEG +KL V + S QL+D +L L E + + + +L+ +
Sbjct: 1292 LQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQEL-LQEETRQKLNVSTKLRQLEE 1350
Query: 674 TKTSLQNKVFLKVDKCITKTRSMMALLVQL 703
+ SLQ+++ +++ R + L +QL
Sbjct: 1351 ERNSLQDQLDEEMEAKQNLERHISTLNIQL 1380
Score = 35.4 bits (80), Expect = 0.19
Identities = 56/256 (21%), Positives = 106/256 (41%), Gaps = 39/256 (15%)
Query: 326 LERMEDFTDSAYTSHEHRERILELSTQARMELQQLISVWIQAQSK---KTKSIAEELELS 382
LE D + + + E+ + M+LQ+ ++ +A+ + + + +AEEL S
Sbjct: 1668 LEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASS 1727
Query: 383 ILKISHSLNELKKELHSTATQLAADLLKYHADHVVLKALKLTGVEGNLEALAEYACKLSE 442
L ++L + K+ L + QL +L + +GN+EA+++ K ++
Sbjct: 1728 -LSGRNALQDEKRRLEARIAQLEEELEEE---------------QGNMEAMSDRVRKATQ 1771
Query: 443 QKEQL-----VETCRLLRHISGTEPLEITCIHAEETFQVTGQQIISAAETLTLHPSSKIA 497
Q EQL E ++ S + LE + S ++ +KIA
Sbjct: 1772 QAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIA 1831
Query: 498 KENLDVFCEAWESQISDMS---------TLLREINDVFEGRRGEKYGYLSLPKPMKNNAN 548
+ V EA E Q + S +L ++ D E + E+Y + K NA
Sbjct: 1832 QLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVED--ERKMAEQY----KEQAEKGNAR 1885
Query: 549 LKSLKPDKPDSEEQAK 564
+K LK ++EE+++
Sbjct: 1886 VKQLKRQLEEAEEESQ 1901
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 40.0 bits (92), Expect = 0.008
Identities = 65/342 (19%), Positives = 139/342 (40%), Gaps = 29/342 (8%)
Query: 315 KENLSVTLEVILERMEDFTDSAYTSHEHRERILE--LSTQARMELQQLISVWIQAQSKKT 372
K+ L L + R+E+ D R+++ + L + ++E ++ +Q +
Sbjct: 924 KQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTA 983
Query: 373 KSIAEELELSILKISHSLNELKKE---LHSTATQLAADLLKYHADHVVLKALKLTGVEGN 429
++ ++LE IL + N+L KE L + L +L + KA LT ++
Sbjct: 984 EAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEE-----KAKNLTKLKNK 1038
Query: 430 LEAL-AEYACKLSEQKEQLVETCRLLRHISGTEPLEITCIHAEETFQVTGQQIISAAETL 488
E++ +E +L ++++ E +L R + G + + H Q+ Q A+
Sbjct: 1039 HESMISELEVRLKKEEKSRQELEKLKRKLEG----DASDFHE----QIADLQ----AQIA 1086
Query: 489 TLHPSSKIAKENLDVFCEAWESQISDMSTLLREINDVFEGRRGEKYGYLSLPKPMKNNAN 548
L +E L + +I+ + L++I ++ EG + L + +N A
Sbjct: 1087 ELKMQLAKKEEELQAALARLDDEIAQKNNALKKIREL-EGHISDLQEDLDSERAARNKA- 1144
Query: 549 LKSLKPDKPDSEEQAKIAKLGLKLGLLTSDADCEIEKWEDQENEIVQYGRNMSSMAYSLY 608
+ K D E+ + K L+ L ++ E+ +QE +++ + + ++
Sbjct: 1145 ----EKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQ 1200
Query: 609 LFTRGEGPLKTSQDLIHQLEVFAAEGLKLTSSVQAFSKQLKD 650
+ + + ++L QLE F L + Q K+ D
Sbjct: 1201 VQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENAD 1242
Score = 37.0 bits (84), Expect = 0.066
Identities = 70/313 (22%), Positives = 128/313 (40%), Gaps = 52/313 (16%)
Query: 326 LERMEDFTDSAYTSHEHRERILELSTQARMELQQLISVWIQAQSK---KTKSIAEELELS 382
LE D + + + E+ + M+LQ+ ++ +A+ + + + +AEEL S
Sbjct: 1668 LEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASS 1727
Query: 383 ILKISHSLNELKKELHSTATQLAADLLKYHADHVVLKALKLTGVEGNLEALAEYACKLSE 442
L ++L + K+ L + QL +L + +GN+EA+++ K ++
Sbjct: 1728 -LSGRNALQDEKRRLEARIAQLEEELEEE---------------QGNMEAMSDRVRKATQ 1771
Query: 443 QKEQL-----VETCRLLRHISGTEPLEITCIHAEETFQVTGQQIISAAETLTLHPSSKIA 497
Q EQL E ++ S + LE + S ++ +KIA
Sbjct: 1772 QAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIA 1831
Query: 498 KENLDVFCEAWESQISDMS---------TLLREINDVFEGRRGEKYGYLSLPKPMKNNAN 548
+ V EA E Q + S +L ++ D E + E+Y + K NA
Sbjct: 1832 QLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVED--ERKMAEQY----KEQAEKGNAR 1885
Query: 549 LKSLKPDKPDSEEQAKIAKLGLKLGLLTSDADCEIEKWEDQENEIVQYGRNMSSMAYSLY 608
+K LK ++EE+++ ++ L + D E E E GR ++++ L
Sbjct: 1886 VKQLKRQLEEAEEESQ--RINANRRKLQRELD---EATESNE----AMGREVNALKSKL- 1935
Query: 609 LFTRGEGPLKTSQ 621
RG P +TSQ
Sbjct: 1936 ---RGPPPQETSQ 1945
Score = 36.2 bits (82), Expect = 0.11
Identities = 109/570 (19%), Positives = 227/570 (39%), Gaps = 79/570 (13%)
Query: 165 KQIITSRNKVLATMERLEKV-NSFQEFVQIFSQFGNEM-VEFAHLSGDRQNDLKDEKKKA 222
+++ +++ T ER +K N +E Q SQ E + L + + + E+ +
Sbjct: 859 EEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRV 918
Query: 223 KMAAARAVLEKCTMMLLTASKTCLRHPNCESAHKNKEGVFDRMKVA---LDKVIEIVTDC 279
++AA + LE+ +L + L E + ++ +R K+A LD ++ +
Sbjct: 919 RLAAKKQELEE----ILHEMEARLE----EEEDRGQQLQAERKKMAQQMLDLEEQLEEEE 970
Query: 280 KPNGETDISSISIFTGIKEFKMNIEALRENLYFQSKENLSVTLEVILERMEDFTDSAYTS 339
+ + ++ IK+ + I + + SKE +++ ER+ D T +
Sbjct: 971 AARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKER-----KLLEERISDLTTNLAEE 1025
Query: 340 HEHRERILELST---------QARMELQQLISVWIQAQSKKTKSIAEELELSILKISHSL 390
E + + +L + R++ ++ ++ +K + A + I + +
Sbjct: 1026 EEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQI 1085
Query: 391 NELKKELHSTATQLAADLLKYHADHVVLK---ALKLTGVEGNLEALAEYACKLSEQKEQL 447
ELK +L +L A L + D + K K+ +EG++ L E L ++
Sbjct: 1086 AELKMQLAKKEEELQAALARLD-DEIAQKNNALKKIRELEGHISDLQE---DLDSERAAR 1141
Query: 448 VETCRLLRHISGTEPLEITCIHAEETFQVTGQQIISAAETLTLHPSSKIAKENLDVFCEA 507
+ + R + E LE E+T T Q A+ + K+ LD +
Sbjct: 1142 NKAEKQKRDLG--EELEALKTELEDTLDSTATQQELRAKR---EQEVTVLKKALDEETRS 1196
Query: 508 WESQISDMSTL-LREINDVFEGRRGEKYGYLSLPKPMKNNANLKSLKPDKPDSEEQAKIA 566
E+Q+ +M + + ++ E K +L K N ++L+ + D + ++
Sbjct: 1197 HEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDK------NKQTLEKENADLAGELRV- 1249
Query: 567 KLGLKLGLLTSDADCEIEKWEDQENEIVQYGRNMSSMAYSLYLFTRGEGPLKTSQDLIHQ 626
LG + + + +K E Q E+ + GE D +H+
Sbjct: 1250 -----LGQAKQEVEHKKKKLEAQVQELQSKCSD-------------GERARAELNDKVHK 1291
Query: 627 LE---------VFAAEG--LKLTSSVQAFSKQLKDDDKLMLLLEINKLIPLCHQLQTV-- 673
L+ + AEG +KL V + S QL+D +L L E + + + +L+ +
Sbjct: 1292 LQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQEL-LQEETRQKLNVSTKLRQLEE 1350
Query: 674 TKTSLQNKVFLKVDKCITKTRSMMALLVQL 703
+ SLQ+++ +++ R + L +QL
Sbjct: 1351 ERNSLQDQLDEEMEAKQNLERHISTLNIQL 1380
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 40.0 bits (92), Expect = 0.008
Identities = 65/342 (19%), Positives = 139/342 (40%), Gaps = 29/342 (8%)
Query: 315 KENLSVTLEVILERMEDFTDSAYTSHEHRERILE--LSTQARMELQQLISVWIQAQSKKT 372
K+ L L + R+E+ D R+++ + L + ++E ++ +Q +
Sbjct: 917 KQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTA 976
Query: 373 KSIAEELELSILKISHSLNELKKE---LHSTATQLAADLLKYHADHVVLKALKLTGVEGN 429
++ ++LE IL + N+L KE L + L +L + KA LT ++
Sbjct: 977 EAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEE-----KAKNLTKLKNK 1031
Query: 430 LEAL-AEYACKLSEQKEQLVETCRLLRHISGTEPLEITCIHAEETFQVTGQQIISAAETL 488
E++ +E +L ++++ E +L R + G + + H Q+ Q A+
Sbjct: 1032 HESMISELEVRLKKEEKSRQELEKLKRKLEG----DASDFHE----QIADLQ----AQIA 1079
Query: 489 TLHPSSKIAKENLDVFCEAWESQISDMSTLLREINDVFEGRRGEKYGYLSLPKPMKNNAN 548
L +E L + +I+ + L++I ++ EG + L + +N A
Sbjct: 1080 ELKMQLAKKEEELQAALARLDDEIAQKNNALKKIREL-EGHISDLQEDLDSERAARNKA- 1137
Query: 549 LKSLKPDKPDSEEQAKIAKLGLKLGLLTSDADCEIEKWEDQENEIVQYGRNMSSMAYSLY 608
+ K D E+ + K L+ L ++ E+ +QE +++ + + ++
Sbjct: 1138 ----EKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQ 1193
Query: 609 LFTRGEGPLKTSQDLIHQLEVFAAEGLKLTSSVQAFSKQLKD 650
+ + + ++L QLE F L + Q K+ D
Sbjct: 1194 VQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENAD 1235
Score = 37.0 bits (84), Expect = 0.066
Identities = 70/313 (22%), Positives = 128/313 (40%), Gaps = 52/313 (16%)
Query: 326 LERMEDFTDSAYTSHEHRERILELSTQARMELQQLISVWIQAQSK---KTKSIAEELELS 382
LE D + + + E+ + M+LQ+ ++ +A+ + + + +AEEL S
Sbjct: 1661 LEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASS 1720
Query: 383 ILKISHSLNELKKELHSTATQLAADLLKYHADHVVLKALKLTGVEGNLEALAEYACKLSE 442
L ++L + K+ L + QL +L + +GN+EA+++ K ++
Sbjct: 1721 -LSGRNALQDEKRRLEARIAQLEEELEEE---------------QGNMEAMSDRVRKATQ 1764
Query: 443 QKEQL-----VETCRLLRHISGTEPLEITCIHAEETFQVTGQQIISAAETLTLHPSSKIA 497
Q EQL E ++ S + LE + S ++ +KIA
Sbjct: 1765 QAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIA 1824
Query: 498 KENLDVFCEAWESQISDMS---------TLLREINDVFEGRRGEKYGYLSLPKPMKNNAN 548
+ V EA E Q + S +L ++ D E + E+Y + K NA
Sbjct: 1825 QLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVED--ERKMAEQY----KEQAEKGNAR 1878
Query: 549 LKSLKPDKPDSEEQAKIAKLGLKLGLLTSDADCEIEKWEDQENEIVQYGRNMSSMAYSLY 608
+K LK ++EE+++ ++ L + D E E E GR ++++ L
Sbjct: 1879 VKQLKRQLEEAEEESQ--RINANRRKLQRELD---EATESNE----AMGREVNALKSKL- 1928
Query: 609 LFTRGEGPLKTSQ 621
RG P +TSQ
Sbjct: 1929 ---RGPPPQETSQ 1938
Score = 36.2 bits (82), Expect = 0.11
Identities = 109/570 (19%), Positives = 227/570 (39%), Gaps = 79/570 (13%)
Query: 165 KQIITSRNKVLATMERLEKV-NSFQEFVQIFSQFGNEM-VEFAHLSGDRQNDLKDEKKKA 222
+++ +++ T ER +K N +E Q SQ E + L + + + E+ +
Sbjct: 852 EEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRV 911
Query: 223 KMAAARAVLEKCTMMLLTASKTCLRHPNCESAHKNKEGVFDRMKVA---LDKVIEIVTDC 279
++AA + LE+ +L + L E + ++ +R K+A LD ++ +
Sbjct: 912 RLAAKKQELEE----ILHEMEARLE----EEEDRGQQLQAERKKMAQQMLDLEEQLEEEE 963
Query: 280 KPNGETDISSISIFTGIKEFKMNIEALRENLYFQSKENLSVTLEVILERMEDFTDSAYTS 339
+ + ++ IK+ + I + + SKE +++ ER+ D T +
Sbjct: 964 AARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKER-----KLLEERISDLTTNLAEE 1018
Query: 340 HEHRERILELST---------QARMELQQLISVWIQAQSKKTKSIAEELELSILKISHSL 390
E + + +L + R++ ++ ++ +K + A + I + +
Sbjct: 1019 EEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQI 1078
Query: 391 NELKKELHSTATQLAADLLKYHADHVVLK---ALKLTGVEGNLEALAEYACKLSEQKEQL 447
ELK +L +L A L + D + K K+ +EG++ L E L ++
Sbjct: 1079 AELKMQLAKKEEELQAALARLD-DEIAQKNNALKKIRELEGHISDLQE---DLDSERAAR 1134
Query: 448 VETCRLLRHISGTEPLEITCIHAEETFQVTGQQIISAAETLTLHPSSKIAKENLDVFCEA 507
+ + R + E LE E+T T Q A+ + K+ LD +
Sbjct: 1135 NKAEKQKRDLG--EELEALKTELEDTLDSTATQQELRAKR---EQEVTVLKKALDEETRS 1189
Query: 508 WESQISDMSTL-LREINDVFEGRRGEKYGYLSLPKPMKNNANLKSLKPDKPDSEEQAKIA 566
E+Q+ +M + + ++ E K +L K N ++L+ + D + ++
Sbjct: 1190 HEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDK------NKQTLEKENADLAGELRV- 1242
Query: 567 KLGLKLGLLTSDADCEIEKWEDQENEIVQYGRNMSSMAYSLYLFTRGEGPLKTSQDLIHQ 626
LG + + + +K E Q E+ + GE D +H+
Sbjct: 1243 -----LGQAKQEVEHKKKKLEAQVQELQSKCSD-------------GERARAELNDKVHK 1284
Query: 627 LE---------VFAAEG--LKLTSSVQAFSKQLKDDDKLMLLLEINKLIPLCHQLQTV-- 673
L+ + AEG +KL V + S QL+D +L L E + + + +L+ +
Sbjct: 1285 LQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQEL-LQEETRQKLNVSTKLRQLEE 1343
Query: 674 TKTSLQNKVFLKVDKCITKTRSMMALLVQL 703
+ SLQ+++ +++ R + L +QL
Sbjct: 1344 ERNSLQDQLDEEMEAKQNLERHISTLNIQL 1373
>gi|40807445 protein regulator of cytokinesis 1 isoform 3 [Homo
sapiens]
Length = 566
Score = 40.0 bits (92), Expect = 0.008
Identities = 38/151 (25%), Positives = 74/151 (49%), Gaps = 15/151 (9%)
Query: 279 CKPNGETDISSISIFTGIKEFKMNIEALRENLYFQSKENLSVTLEVILERMEDFTDSAYT 338
C P+ + D +S+ + +F+ ++ LRE + +E +S+ ++IL ME+ + T
Sbjct: 136 CMPHYDIDSASVPSLEELNQFRQHVTTLRETKASRREEFVSIKRQIIL-CMEELDHTPDT 194
Query: 339 SHEHRERILE------LSTQARMELQQLISVWIQAQSKKTKSIAEELELSILKISHSLNE 392
S E R+ + E LS + LQ+L+ ++ Q + +++ E L I ++ L
Sbjct: 195 SFE-RDVVCEDEDAFCLSLENIATLQKLLR-QLEMQKSQNEAVCEGLRTQIRELWDRLQI 252
Query: 393 LKKELHSTATQLAADLLKYHADHVVLKALKL 423
++E + AT ++ K V KAL+L
Sbjct: 253 PEEEREAVATIMSGSKAK------VRKALQL 277
>gi|40807443 protein regulator of cytokinesis 1 isoform 2 [Homo
sapiens]
Length = 606
Score = 40.0 bits (92), Expect = 0.008
Identities = 38/151 (25%), Positives = 74/151 (49%), Gaps = 15/151 (9%)
Query: 279 CKPNGETDISSISIFTGIKEFKMNIEALRENLYFQSKENLSVTLEVILERMEDFTDSAYT 338
C P+ + D +S+ + +F+ ++ LRE + +E +S+ ++IL ME+ + T
Sbjct: 136 CMPHYDIDSASVPSLEELNQFRQHVTTLRETKASRREEFVSIKRQIIL-CMEELDHTPDT 194
Query: 339 SHEHRERILE------LSTQARMELQQLISVWIQAQSKKTKSIAEELELSILKISHSLNE 392
S E R+ + E LS + LQ+L+ ++ Q + +++ E L I ++ L
Sbjct: 195 SFE-RDVVCEDEDAFCLSLENIATLQKLLR-QLEMQKSQNEAVCEGLRTQIRELWDRLQI 252
Query: 393 LKKELHSTATQLAADLLKYHADHVVLKALKL 423
++E + AT ++ K V KAL+L
Sbjct: 253 PEEEREAVATIMSGSKAK------VRKALQL 277
>gi|4506039 protein regulator of cytokinesis 1 isoform 1 [Homo
sapiens]
Length = 620
Score = 40.0 bits (92), Expect = 0.008
Identities = 38/151 (25%), Positives = 74/151 (49%), Gaps = 15/151 (9%)
Query: 279 CKPNGETDISSISIFTGIKEFKMNIEALRENLYFQSKENLSVTLEVILERMEDFTDSAYT 338
C P+ + D +S+ + +F+ ++ LRE + +E +S+ ++IL ME+ + T
Sbjct: 136 CMPHYDIDSASVPSLEELNQFRQHVTTLRETKASRREEFVSIKRQIIL-CMEELDHTPDT 194
Query: 339 SHEHRERILE------LSTQARMELQQLISVWIQAQSKKTKSIAEELELSILKISHSLNE 392
S E R+ + E LS + LQ+L+ ++ Q + +++ E L I ++ L
Sbjct: 195 SFE-RDVVCEDEDAFCLSLENIATLQKLLR-QLEMQKSQNEAVCEGLRTQIRELWDRLQI 252
Query: 393 LKKELHSTATQLAADLLKYHADHVVLKALKL 423
++E + AT ++ K V KAL+L
Sbjct: 253 PEEEREAVATIMSGSKAK------VRKALQL 277
>gi|118498356 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 38.9 bits (89), Expect = 0.017
Identities = 42/169 (24%), Positives = 79/169 (46%), Gaps = 12/169 (7%)
Query: 365 IQAQSKKTKSIAEELELSILKISH---SLNELKKELHSTATQLA-ADLLKYHADHVVLKA 420
I + K KS+ E LE +LK+++ ++ +LK+E+ + ++ L K + K
Sbjct: 803 IHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKV 862
Query: 421 LKLTG-VEGNLEALAEYACKLSEQKEQLVETCRLLRHISGTEPLEITCIHAEETFQVTGQ 479
+L ++G E + L E+++ L T + L+ + E E H +E Q +
Sbjct: 863 QELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQ--EENESLKAHVQEVAQHNLK 920
Query: 480 QIISAAETLTLHPSSKIAKEN----LDVFCEAWESQISDMSTLLREIND 524
+ SA++ L K KEN L+ + ES +S + LL+++ D
Sbjct: 921 EASSASQFEELEIVLK-EKENELKRLEAMLKERESDLSSKTQLLQDVQD 968
>gi|33620775 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 38.9 bits (89), Expect = 0.017
Identities = 42/169 (24%), Positives = 79/169 (46%), Gaps = 12/169 (7%)
Query: 365 IQAQSKKTKSIAEELELSILKISH---SLNELKKELHSTATQLA-ADLLKYHADHVVLKA 420
I + K KS+ E LE +LK+++ ++ +LK+E+ + ++ L K + K
Sbjct: 803 IHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKV 862
Query: 421 LKLTG-VEGNLEALAEYACKLSEQKEQLVETCRLLRHISGTEPLEITCIHAEETFQVTGQ 479
+L ++G E + L E+++ L T + L+ + E E H +E Q +
Sbjct: 863 QELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQ--EENESLKAHVQEVAQHNLK 920
Query: 480 QIISAAETLTLHPSSKIAKEN----LDVFCEAWESQISDMSTLLREIND 524
+ SA++ L K KEN L+ + ES +S + LL+++ D
Sbjct: 921 EASSASQFEELEIVLK-EKENELKRLEAMLKERESDLSSKTQLLQDVQD 968
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 38.5 bits (88), Expect = 0.023
Identities = 86/417 (20%), Positives = 176/417 (42%), Gaps = 51/417 (12%)
Query: 217 DEKKKAKMAAARAVLEKCTMMLLTASKTCLRHPNCESAHKNKEGVFDRMKVALDKVIEIV 276
+++K A + + E+ T + SK + + AH+ D ++V DKV ++
Sbjct: 969 EKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQ---TLDDLQVEEDKVNGLI 1025
Query: 277 TDCKPNGETDISSISIFTGIKEFKMNIEALRENLYFQSKENLSVTLEVILERMEDF-TDS 335
K N + + + + +++ K LR +L ++K L L++ E + D D
Sbjct: 1026 ---KINAKLEQQTDDLEGSLEQEKK----LRADLE-RAKRKLEGDLKMSQESIMDLENDK 1077
Query: 336 AYTSHEHRERILELST-QARMELQQLISVWIQAQSKKTKSIAEELELSI-------LKIS 387
+ +++ ELS QA+++ +Q+ S+ Q + K+ ++ EELE I KI
Sbjct: 1078 QQIEEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIE 1137
Query: 388 HSLNELKKELHSTATQL--AADLLKYHADHVVLKALKLTGVEGNLE--ALAEYACKLSEQ 443
++L +EL + +L A+ + + + + +LE L A + +
Sbjct: 1138 KQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLR 1197
Query: 444 KEQLVETCRLLRHISGTEPLEITCIHAEETFQVTGQQIISAAETLTLHPSSKIAKENLDV 503
K+Q L I + ++ + ++ + S E L+ +K N++
Sbjct: 1198 KKQADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSK------SKSNIER 1251
Query: 504 FCEAWESQISDM-------STLLREINDVFEGRRGEKYGYLSLPKPMKNN---------- 546
C E Q S++ + L+ ++N + + R + G LS K +
Sbjct: 1252 TCRTVEDQFSEIKAKDEQQTQLIHDLN-MQKARLQTQNGELSHRVEEKESLISQLTKSKQ 1310
Query: 547 ANLKSLKPDKPDSEEQAKIAKLGLKLGLLTSDADCEI--EKWEDQENEIVQYGRNMS 601
A + L+ K EE+ K AK + L +S DC++ E++E+++ + R +S
Sbjct: 1311 ALTQQLEELKRQMEEETK-AKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALS 1366
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 38.5 bits (88), Expect = 0.023
Identities = 76/384 (19%), Positives = 163/384 (42%), Gaps = 44/384 (11%)
Query: 284 ETDIS-SISIFTGIKEFKMNIEALRENLYFQSKENLSVTLEVILERMEDFTDSAYTSHEH 342
E D++ S+ T ++E + ++ L E + K +S + E+F S +SHE
Sbjct: 1140 EVDLNKSLKENTFLQEQLVELKMLAE----EDKRKVSELTSKLKTTDEEF-QSLKSSHEK 1194
Query: 343 RERILELSTQARMELQQLISVWIQAQSKKTKSIAEELELSILKISHS-----LNELKKEL 397
+ LE + +L + +++ + KKT+++ E ++ IS S L+ +
Sbjct: 1195 SNKSLEDKSLEFKKLSEELAIQLDICCKKTEALLEAKTNELINISSSKTNAILSRISHCQ 1254
Query: 398 HSTATQLAADLLK-YHADHVVLKALKLTGVEGNLEALAEYACKLSEQKEQLVETCRLLRH 456
H T A L+K + + +LT + L + A E+KE +++ +
Sbjct: 1255 HRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMK---- 1310
Query: 457 ISGTEPLEITCIHAEETFQVTG--QQIISAAETLTLHPSSKIAKENLD---VFCEAWESQ 511
+ E L + +E Q G QQ ++ + + K EN++ + E + +
Sbjct: 1311 -ADIESL----VTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEK 1365
Query: 512 ISDMSTLLREINDVFEGRRGEKYGYLSLPKPMKNNANLKSLKP--DKPDSEEQAKIAKLG 569
++S+L +++ D+ + +SL + A + SL+ D+ E ++ L
Sbjct: 1366 KVEISSLSKQLTDL----NVQLQNSISL---SEKEAAISSLRKQYDEEKCELLDQVQDLS 1418
Query: 570 LKLGLLTSDADCEIEKWEDQENEIVQYGRNMSSMAYSLYLFTRGEGPLKTSQDLIHQLEV 629
K+ L+ + +E+ +D N+ ++ + S FT+ + +K +L QLE+
Sbjct: 1419 FKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSR------FTQHQNTVK---ELQIQLEL 1469
Query: 630 FAAEGLKLTSSVQAFSKQLKDDDK 653
+ E + + ++L +K
Sbjct: 1470 KSKEAYEKDEQINLLKEELDQQNK 1493
Score = 37.7 bits (86), Expect = 0.038
Identities = 65/364 (17%), Positives = 160/364 (43%), Gaps = 31/364 (8%)
Query: 47 QITTLIN-HKDNTKKSDKTLQAIQRVGQAVNLAVGRFVKVGEAIANENWDLKEEINIACI 105
Q+ ++I H+ + ++++K L+ ++ Q L R + E A+ +L+ +I +
Sbjct: 735 QVDSIIKEHEVSIQRTEKALK--DQINQLELLLKERDKHLKEHQAHVE-NLEADIKRSEG 791
Query: 106 EAKQAGETIAALTDITNLNHLES---DGQITIFTDKTGVIKAARLLLSSVTKVLLLADRV 162
E +QA + + H ++ + Q+ K ++ R+LL+ + +
Sbjct: 792 ELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKD 851
Query: 163 VIKQIITSRNKVLATMERLEKVNS-FQEFVQIFSQFGNEMVEFAHLSGDRQNDLKDEKKK 221
V ++ + +V M++LEK NS ++ V+ +Q +E + ++ + EK+
Sbjct: 852 VCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKEN 911
Query: 222 AKMAAARAVLEKCTMML--LTASKTCLRHPN--CESAHKNKEGVFDRMKVALDKVIEIVT 277
+ ++ ++ L+A + + N E+ KN+E +++K ++ E +
Sbjct: 912 MILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLK 971
Query: 278 ----DCKPNGETDISSISIFTGIKEFKMNIEALRENLYFQSKENLSVTLEVILERMEDFT 333
D + + ++ + ++ KE + N + L + + S + + R+E
Sbjct: 972 KKLLDQEAKLKKELENTALELSQKEKQFNAKML------EMAQANSAGISDAVSRLET-- 1023
Query: 334 DSAYTSHEHRERILELSTQARMELQQLISVWIQAQSKKTKSIAEELELSILKISHSLNEL 393
+E+I L+ R EL +IS+W + +++ + + E E+ + + + EL
Sbjct: 1024 -------NQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAEL 1076
Query: 394 KKEL 397
K+++
Sbjct: 1077 KQKI 1080
Score = 30.0 bits (66), Expect = 8.0
Identities = 124/682 (18%), Positives = 251/682 (36%), Gaps = 134/682 (19%)
Query: 46 SQITTLINHKDNTKKSDKTLQAIQRVGQAVNLAVGRFVKVGEAIANENWDLKEEIN-IAC 104
+ + TL + K+ + L+ + Q+ EA+ + + +E+ I
Sbjct: 276 TSVKTLETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKD 335
Query: 105 IEAKQAGETIAALTDITNL-NHLESDGQITIFTDKTGVIKAARLLLSSVTKVLLLADRVV 163
+ + + I L D NL LE D + I K + + + + ++ R
Sbjct: 336 LHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQL-----RSR 390
Query: 164 IKQIITSRNKVLATMERLEKVNSFQEFVQIFS--------------QFGNEMVEFAHLSG 209
IKQ+ T ++ E+ E+ +F+E + S + ++ S
Sbjct: 391 IKQMTTQGEELREQKEKSERA-AFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSE 449
Query: 210 DRQNDLKDEKKKAKMAAARAVLEK-----CTMMLLTASKTCLRHPNCESAHKNKEGVF-D 263
+ + L+ E + K + + + L + + + +E F +
Sbjct: 450 EERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQE 509
Query: 264 RMKVALDKVIEIVTDCKPNGETDISSISIFTGIKEFKMNIEALR-ENLYFQSKENLSVTL 322
+MKVAL+K S S + I + K E+L E L Q K
Sbjct: 510 QMKVALEK-----------------SQSEYLKISQEKEQQESLALEELELQKKA------ 546
Query: 323 EVILERMEDFTDSAYTSHEHRERILELSTQARMELQQL------ISVWIQAQS------- 369
++ E D + +R RILEL + LQ+ ++V ++A+
Sbjct: 547 -ILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEI 605
Query: 370 ----KKTKSIAEEL----------ELSILKISH--SLNELKKELHSTATQLAAD---LLK 410
+K K+ E L +L +LK + + +L+++ L D + +
Sbjct: 606 TVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQ 665
Query: 411 YHADHVVLKAL-KLTGVEGNLEALAEYACKLSEQKEQLVETCRLLRHISG--TEPLEITC 467
H + + K L KL + LE+L+ ++ + + +L E +L+ + + LE
Sbjct: 666 AHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKM 725
Query: 468 IHAEETFQVTGQQIISAAETLTLHPSSKIAKENLDVFCEAWESQISDMSTLLREINDVFE 527
+ Q II E +++ + K K+ QI+ + LL+E + +
Sbjct: 726 DEQKNHHQQQVDSIIKEHE-VSIQRTEKALKD-----------QINQLELLLKERDKHLK 773
Query: 528 GRRGEKYGYLSLPKPMKNNANLKSLKPDKPDSEEQAKIAKLGLKLGLLTSDADCEIEKWE 587
++ A++++L+ D SE ++ + KL + S E+ +
Sbjct: 774 ----------------EHQAHVENLEADIKRSE--GELQQASAKLDVFQSYQSATHEQTK 815
Query: 588 DQENEIVQYGRNMSSMAYSLYLFTRGEGPLKTS---------------QDLIHQLEVFAA 632
E ++ Q + + + L T+ ++ QDL+ QLE +
Sbjct: 816 AYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNS 875
Query: 633 E-GLKLTSSVQAFSKQLKDDDK 653
E K+ S Q + +L+D +K
Sbjct: 876 EMEQKVKSLTQVYESKLEDGNK 897
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 38.5 bits (88), Expect = 0.023
Identities = 76/379 (20%), Positives = 148/379 (39%), Gaps = 42/379 (11%)
Query: 252 ESAHKNKEGVFDRMKVALDKVIEIVTDCKPNGETDISSIS-IFTGIKEFKMNIEALRENL 310
++ + + D ++ DKV I+T K E + + K+ +M++E + L
Sbjct: 1000 KALQETHQQTLDDLQAEEDKV-NILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKL 1058
Query: 311 YFQSK---------ENLSVTLEVILERMEDFTDSAYTSHEHRERILELSTQARMELQQLI 361
K EN L+ LE+ E F S S E+ +E+ Q +++ Q
Sbjct: 1059 EGDLKLAQESTMDMENDKQQLDEKLEKKE-FEISNLISKIEDEQAVEIQLQKKIKELQAR 1117
Query: 362 SVWIQAQSKKTKSIAEELELSILKISHSLNELKKELHSTATQLAADLLKYHADHVVLKAL 421
+ + + ++ + E +S L E+ + L +A + + L
Sbjct: 1118 IEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKL 1177
Query: 422 KLTGVEGNLEALAEYACKLSEQKEQLVETCRLLRHISGTEPLEITCIHAEETFQVTGQQI 481
+ E L+ A A + + + E L I + ++ + ++ +
Sbjct: 1178 RRDLEEATLQHEAMVAALRKKHADSMAE---LGEQIDNLQRVKQKLEKEKSELKMETDDL 1234
Query: 482 ISAAETLTLHPSSKIAKENLDVFCEAWESQISDMSTLLRE----INDV------------ 525
S AE ++ AK NL+ C + E Q+S++ T E IND+
Sbjct: 1235 SSNAEAISK------AKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAG 1288
Query: 526 -FEGRRGEKYGYLSLPKPMKNNANLKSLKPDKPDSEEQAKIAKLGLKLGLLTSDADCEI- 583
+ + EK +S K A+ + ++ K EE+ K AK L L +S DC++
Sbjct: 1289 EYSRQLDEKDALVSQLSRSK-QASTQQIEELKHQLEEETK-AKNALAHALQSSRHDCDLL 1346
Query: 584 -EKWEDQENEIVQYGRNMS 601
E++E+++ + R +S
Sbjct: 1347 REQYEEEQEGKAELQRALS 1365
Score = 30.8 bits (68), Expect = 4.7
Identities = 35/154 (22%), Positives = 63/154 (40%), Gaps = 33/154 (21%)
Query: 306 LRENLYFQSKENLSVTLEVILERMEDFTDSAYTSHEHRERILELSTQA---------RME 356
L E + KE + L+V E DS + E E++++ Q R E
Sbjct: 876 LEEKMVTLLKEKNDLQLQVQSE-----ADSLADAEERCEQLIKNKIQLEAKIKEVTERAE 930
Query: 357 LQQLISVWIQAQSKKTKSIAEELELSILKISHSLNELKKELHSTATQLAADLLKYHADHV 416
++ I+ + A+ +K + EL+ I + +L +++KE H+T
Sbjct: 931 EEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATEN-------------- 976
Query: 417 VLKALKLTGVEGNLEALAEYACKLSEQKEQLVET 450
K+ + + L E KLS++K+ L ET
Sbjct: 977 -----KVKNLTEEMAGLDETIAKLSKEKKALQET 1005
>gi|112734867 retinitis pigmentosa GTPase regulator interacting
protein 1 [Homo sapiens]
Length = 1286
Score = 38.1 bits (87), Expect = 0.029
Identities = 41/194 (21%), Positives = 85/194 (43%), Gaps = 10/194 (5%)
Query: 219 KKKAKMAAARAVL-EKCTMMLLTASKTCLRHPNCESAHKNKEGVFDRMKVALDKVI-EIV 276
K+K ++ + +L E+ +++T ++ E+ + +G+ AL K + E+
Sbjct: 271 KEKVELIRLKKLLHERNASLVMTKAQLTEVQEAYETLLQKNQGILSAAHEALLKQVNELR 330
Query: 277 TDCKPNGETDISSISIFTGIKEFKMNIEALRENLYFQSKEN--LSVTLEVILERMEDFTD 334
+ K + +S S + +M ++ +E + KE L+ + +LE M D +D
Sbjct: 331 AELKEESKKAVSLKSQLEDVSILQMTLKEFQERVEDLEKERKLLNDNYDKLLESMLDSSD 390
Query: 335 SAYTSHEHRERILELSTQARMELQQLISVWIQAQSK------KTKSIAEELELSILKISH 388
S+ H E I E Q +LQ + ++ + K + K+ E+L+L + I
Sbjct: 391 SSSQPHWSNELIAEQLQQQVSQLQDQLDAELEDKRKVLLELSREKAQNEDLKLEVTNILQ 450
Query: 389 SLNELKKELHSTAT 402
+ + L + AT
Sbjct: 451 KHKQEVELLQNAAT 464
>gi|4507877 vinculin isoform VCL [Homo sapiens]
Length = 1066
Score = 37.7 bits (86), Expect = 0.038
Identities = 34/163 (20%), Positives = 63/163 (38%), Gaps = 11/163 (6%)
Query: 366 QAQSKKTKSIAEELELSILKISHSLNELKKELHSTATQLAADLLKYHADHVVLKALKLTG 425
+ +S + +++A +L+ SL +LK + TQ +D+ + L A+ T
Sbjct: 563 EGESPQARALASQLQ-------DSLKDLKARMQEAMTQEVSDVFSDTTTPIKLLAVAATA 615
Query: 426 ---VEGNLEALAEYACKLSEQKEQLVETCRLLRHISGTEPLEITCIHAE-ETFQVTGQQI 481
E E A +L T + + I A +T + Q+
Sbjct: 616 PPDAPNREEVFDERAANFENHSGKLGATAEKAAAVGTANKSTVEGIQASVKTARELTPQV 675
Query: 482 ISAAETLTLHPSSKIAKENLDVFCEAWESQISDMSTLLREIND 524
+SAA L +P ++ A E+ + W + M+ L+ E D
Sbjct: 676 VSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAID 718
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.130 0.354
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,641,189
Number of Sequences: 37866
Number of extensions: 954030
Number of successful extensions: 4314
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 144
Number of HSP's that attempted gapping in prelim test: 4113
Number of HSP's gapped (non-prelim): 324
length of query: 734
length of database: 18,247,518
effective HSP length: 110
effective length of query: 624
effective length of database: 14,082,258
effective search space: 8787328992
effective search space used: 8787328992
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.