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Search of human proteins with 4502923
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4502923 calponin 3 [Homo sapiens]
(329 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4502923 calponin 3 [Homo sapiens] 674 0.0
gi|21361120 calponin 1, basic, smooth muscle [Homo sapiens] 414 e-116
gi|4758018 calponin 2 isoform a [Homo sapiens] 396 e-110
gi|41327730 calponin 2 isoform b [Homo sapiens] 326 2e-89
gi|48255907 transgelin [Homo sapiens] 147 1e-35
gi|48255905 transgelin [Homo sapiens] 147 1e-35
gi|4507357 transgelin 2 [Homo sapiens] 146 2e-35
gi|56549135 transgelin 3 [Homo sapiens] 145 4e-35
gi|56549139 transgelin 3 [Homo sapiens] 145 4e-35
gi|56549137 transgelin 3 [Homo sapiens] 145 4e-35
gi|163310745 LIM and calponin homology domains 1 isoform c [Homo... 73 3e-13
gi|163310743 LIM and calponin homology domains 1 isoform b [Homo... 73 3e-13
gi|163310741 LIM and calponin homology domains 1 isoform a [Homo... 73 3e-13
gi|33598968 LIM domain only 7 isoform 1 [Homo sapiens] 62 5e-10
gi|22027528 PAK-interacting exchange factor beta isoform b [Homo... 50 2e-06
gi|22027525 Rac/Cdc42 guanine nucleotide exchange factor 6 [Homo... 50 3e-06
gi|154091020 leucine-rich repeats and calponin homology (CH) dom... 49 5e-06
gi|7108367 vav 1 guanine nucleotide exchange factor [Homo sapiens] 46 5e-05
gi|120432044 vav 3 guanine nucleotide exchange factor isoform 1 ... 45 7e-05
gi|33859670 leucine-rich repeats and calponin homology (CH) doma... 45 7e-05
gi|166064034 PAK-interacting exchange factor beta isoform c [Hom... 44 2e-04
gi|197304715 vav 2 guanine nucleotide exchange factor isoform 1 ... 44 2e-04
gi|40549448 vav 2 guanine nucleotide exchange factor isoform 2 [... 44 2e-04
gi|30181233 leucine-rich repeats and calponin homology (CH) doma... 40 0.002
gi|166064036 PAK-interacting exchange factor beta isoform d [Hom... 39 0.005
gi|4506787 IQ motif containing GTPase activating protein 1 [Homo... 37 0.024
gi|28372563 growth arrest-specific 2 like 3 [Homo sapiens] 35 0.092
gi|21281675 growth arrest-specific 2 like 2 [Homo sapiens] 35 0.12
gi|14249428 leucine-rich repeats and calponin homology (CH) doma... 35 0.12
gi|134142826 pericentriolar material 1 [Homo sapiens] 32 1.0
>gi|4502923 calponin 3 [Homo sapiens]
Length = 329
Score = 674 bits (1740), Expect = 0.0
Identities = 329/329 (100%), Positives = 329/329 (100%)
Query: 1 MTHFNKGPSYGLSAEVKNKIASKYDHQAEEDLRNWIEEVTGMSIGPNFQLGLKDGIILCE 60
MTHFNKGPSYGLSAEVKNKIASKYDHQAEEDLRNWIEEVTGMSIGPNFQLGLKDGIILCE
Sbjct: 1 MTHFNKGPSYGLSAEVKNKIASKYDHQAEEDLRNWIEEVTGMSIGPNFQLGLKDGIILCE 60
Query: 61 LINKLQPGSVKKVNESSLNWPQLENIGNFIKAIQAYGMKPHDIFEANDLFENGNMTQVQT 120
LINKLQPGSVKKVNESSLNWPQLENIGNFIKAIQAYGMKPHDIFEANDLFENGNMTQVQT
Sbjct: 61 LINKLQPGSVKKVNESSLNWPQLENIGNFIKAIQAYGMKPHDIFEANDLFENGNMTQVQT 120
Query: 121 TLVALAGLAKTKGFHTTIDIGVKYAEKQTRRFDEGKLKAGQSVIGLQMGTNKCASQAGMT 180
TLVALAGLAKTKGFHTTIDIGVKYAEKQTRRFDEGKLKAGQSVIGLQMGTNKCASQAGMT
Sbjct: 121 TLVALAGLAKTKGFHTTIDIGVKYAEKQTRRFDEGKLKAGQSVIGLQMGTNKCASQAGMT 180
Query: 181 AYGTRRHLYDPKMQTDKPFDQTTISLQMGTNKGASQAGMLAPGTRRDIYDQKLTLQPVDN 240
AYGTRRHLYDPKMQTDKPFDQTTISLQMGTNKGASQAGMLAPGTRRDIYDQKLTLQPVDN
Sbjct: 181 AYGTRRHLYDPKMQTDKPFDQTTISLQMGTNKGASQAGMLAPGTRRDIYDQKLTLQPVDN 240
Query: 241 STISLQMGTNKVASQKGMSVYGLGRQVYDPKYCAAPTEPVIHNGSQGTGTNGSEISDSDY 300
STISLQMGTNKVASQKGMSVYGLGRQVYDPKYCAAPTEPVIHNGSQGTGTNGSEISDSDY
Sbjct: 241 STISLQMGTNKVASQKGMSVYGLGRQVYDPKYCAAPTEPVIHNGSQGTGTNGSEISDSDY 300
Query: 301 QAEYPDEYHGEYQDDYPRDYQYSDQGIDY 329
QAEYPDEYHGEYQDDYPRDYQYSDQGIDY
Sbjct: 301 QAEYPDEYHGEYQDDYPRDYQYSDQGIDY 329
>gi|21361120 calponin 1, basic, smooth muscle [Homo sapiens]
Length = 297
Score = 414 bits (1063), Expect = e-116
Identities = 201/277 (72%), Positives = 232/277 (83%), Gaps = 2/277 (0%)
Query: 3 HFNKGPSYGLSAEVKNKIASKYDHQAEEDLRNWIEEVTGMSIGPNFQLGLKDGIILCELI 62
HFN+GP+YGLSAEVKNK+A KYDHQ E++LR WIE VTG IG NF GLKDGIILCE I
Sbjct: 5 HFNRGPAYGLSAEVKNKLAQKYDHQREQELREWIEGVTGRRIGNNFMDGLKDGIILCEFI 64
Query: 63 NKLQPGSVKKVNESSLNWPQLENIGNFIKAIQAYGMKPHDIFEANDLFENGNMTQVQTTL 122
NKLQPGSVKK+NES+ NW QLENIGNFIKAI YG+KPHDIFEANDLFEN N TQVQ+TL
Sbjct: 65 NKLQPGSVKKINESTQNWHQLENIGNFIKAITKYGVKPHDIFEANDLFENTNHTQVQSTL 124
Query: 123 VALAGLAKTKGFHTTIDIGVKYAEKQTRRFDEGKLKAGQSVIGLQMGTNKCASQAGMTAY 182
+ALA +AKTKG +++GVKYAEKQ R+F+ GKL+ G+++IGLQMGTNK ASQ GMTAY
Sbjct: 125 LALASMAKTKG--NKVNVGVKYAEKQERKFEPGKLREGRNIIGLQMGTNKFASQQGMTAY 182
Query: 183 GTRRHLYDPKMQTDKPFDQTTISLQMGTNKGASQAGMLAPGTRRDIYDQKLTLQPVDNST 242
GTRRHLYDPK+ TD+P DQ TISLQMGTNKGASQAGM APGT+R I++ L ++ D
Sbjct: 183 GTRRHLYDPKLGTDQPLDQATISLQMGTNKGASQAGMTAPGTKRQIFEPGLGMEHCDTLN 242
Query: 243 ISLQMGTNKVASQKGMSVYGLGRQVYDPKYCAAPTEP 279
+SLQMG+NK ASQ+GM+VYGL RQVYDPKYC P P
Sbjct: 243 VSLQMGSNKGASQRGMTVYGLPRQVYDPKYCLTPEYP 279
>gi|4758018 calponin 2 isoform a [Homo sapiens]
Length = 309
Score = 396 bits (1018), Expect = e-110
Identities = 203/310 (65%), Positives = 232/310 (74%), Gaps = 7/310 (2%)
Query: 2 THFNKGPSYGLSAEVKNKIASKYDHQAEEDLRNWIEEVTGMSIGPNFQLGLKDGIILCEL 61
T FNKGPSYGLSAEVKN++ SKYD Q E +LR WIE +TG+SIGP+FQ GLKDG ILC L
Sbjct: 4 TQFNKGPSYGLSAEVKNRLLSKYDPQKEAELRTWIEGLTGLSIGPDFQKGLKDGTILCTL 63
Query: 62 INKLQPGSVKKVNESSLNWPQLENIGNFIKAIQAYGMKPHDIFEANDLFENGNMTQVQTT 121
+NKLQPGSV K+N S NW QLEN+ NFIKA+ +YGM P D+FEANDLFE+GNMTQVQ +
Sbjct: 64 MNKLQPGSVPKINRSMQNWHQLENLSNFIKAMVSYGMNPVDLFEANDLFESGNMTQVQVS 123
Query: 122 LVALAGLAKTKGFHTTIDIGVKYAEKQTRRFDEGKLKAGQSVIGLQMGTNKCASQAGMTA 181
L+ALAG AKTKG + +DIGVKY+EKQ R FD+ +KAGQ VIGLQMGTNKCASQ+GMTA
Sbjct: 124 LLALAGKAKTKGLQSGVDIGVKYSEKQERNFDDATMKAGQCVIGLQMGTNKCASQSGMTA 183
Query: 182 YGTRRHLYDPKMQTDKPFDQTTISLQMGTNKGASQAGMLAPGTRRDIYDQKLTLQPVDNS 241
YGTRRHLYDPK P D +TISLQMGTNK ASQ GM APGTRR IYD KL DNS
Sbjct: 184 YGTRRHLYDPKNHILPPMDHSTISLQMGTNKCASQVGMTAPGTRRHIYDTKLGTDKCDNS 243
Query: 242 TISLQMGTNKVASQKGMSVYGLGRQVYDPKYCAAPTEPVIHNGSQGTGTNGSEISDSDYQ 301
++SLQMG + A+Q G V+GLGRQ+YDPKYC P V GTG + D
Sbjct: 244 SMSLQMGYTQGANQSG-QVFGLGRQIYDPKYC--PQGTVADGAPSGTG----DCPDPGEV 296
Query: 302 AEYPDEYHGE 311
EYP Y E
Sbjct: 297 PEYPPYYQEE 306
>gi|41327730 calponin 2 isoform b [Homo sapiens]
Length = 270
Score = 326 bits (835), Expect = 2e-89
Identities = 177/310 (57%), Positives = 202/310 (65%), Gaps = 46/310 (14%)
Query: 2 THFNKGPSYGLSAEVKNKIASKYDHQAEEDLRNWIEEVTGMSIGPNFQLGLKDGIILCEL 61
T FNKGPSYGLSAEVKN++ SKYD Q E +LR WIE +TG+SIGP+FQ GLKDG ILC L
Sbjct: 4 TQFNKGPSYGLSAEVKNRLLSKYDPQKEAELRTWIEGLTGLSIGPDFQKGLKDGTILCTL 63
Query: 62 INKLQPGSVKKVNESSLNWPQLENIGNFIKAIQAYGMKPHDIFEANDLFENGNMTQVQTT 121
+NKLQPGSV K+N S NW QLEN+ NFIKA+ +YGM P D+FEANDLFE+GNMTQVQ +
Sbjct: 64 MNKLQPGSVPKINRSMQNWHQLENLSNFIKAMVSYGMNPVDLFEANDLFESGNMTQVQVS 123
Query: 122 LVALAGLAKTKGFHTTIDIGVKYAEKQTRRFDEGKLKAGQSVIGLQMGTNKCASQAGMTA 181
L+ALAG +MGTNKCASQ+GMTA
Sbjct: 124 LLALAG---------------------------------------KMGTNKCASQSGMTA 144
Query: 182 YGTRRHLYDPKMQTDKPFDQTTISLQMGTNKGASQAGMLAPGTRRDIYDQKLTLQPVDNS 241
YGTRRHLYDPK P D +TISLQMGTNK ASQ GM APGTRR IYD KL DNS
Sbjct: 145 YGTRRHLYDPKNHILPPMDHSTISLQMGTNKCASQVGMTAPGTRRHIYDTKLGTDKCDNS 204
Query: 242 TISLQMGTNKVASQKGMSVYGLGRQVYDPKYCAAPTEPVIHNGSQGTGTNGSEISDSDYQ 301
++SLQMG + A+Q G V+GLGRQ+YDPKYC P V GTG + D
Sbjct: 205 SMSLQMGYTQGANQSG-QVFGLGRQIYDPKYC--PQGTVADGAPSGTG----DCPDPGEV 257
Query: 302 AEYPDEYHGE 311
EYP Y E
Sbjct: 258 PEYPPYYQEE 267
>gi|48255907 transgelin [Homo sapiens]
Length = 201
Score = 147 bits (372), Expect = 1e-35
Identities = 86/197 (43%), Positives = 118/197 (59%), Gaps = 13/197 (6%)
Query: 5 NKGPSYGLSAEVKNKIASKYDHQAEEDLRNWIEEVTGMSIGP------NFQLGLKDGIIL 58
NKGPSYG+S EV++KI KYD + EE L WI G +G FQ+ LK+G+IL
Sbjct: 3 NKGPSYGMSREVQSKIEKKYDEELEERLVEWIIVQCGPDVGRPDRGRLGFQVWLKNGVIL 62
Query: 59 CELINKLQPGSVKKV----NESSLNWPQLENIGNFIKAIQAYGMKPHDIFEANDLFENGN 114
+L+N L P K V N S+ + Q+E + F+KA + YG+ D+F+ DLFE +
Sbjct: 63 SKLVNSLYPDGSKPVKVPENPPSMVFKQMEQVAQFLKAAEDYGVIKTDMFQTVDLFEGKD 122
Query: 115 MTQVQTTLVALAGLAKTKG---FHTTIDIGVKYAEKQTRRFDEGKLKAGQSVIGLQMGTN 171
M VQ TL+AL LA TK + + +K A++ R F E +L+ G+ VIGLQMG+N
Sbjct: 123 MAAVQRTLMALGSLAVTKNDGHYRGDPNWFMKKAQEHKREFTESQLQEGKHVIGLQMGSN 182
Query: 172 KCASQAGMTAYGTRRHL 188
+ ASQAGMT YG R +
Sbjct: 183 RGASQAGMTGYGRPRQI 199
Score = 32.7 bits (73), Expect = 0.46
Identities = 15/25 (60%), Positives = 19/25 (76%)
Query: 243 ISLQMGTNKVASQKGMSVYGLGRQV 267
I LQMG+N+ ASQ GM+ YG RQ+
Sbjct: 175 IGLQMGSNRGASQAGMTGYGRPRQI 199
>gi|48255905 transgelin [Homo sapiens]
Length = 201
Score = 147 bits (372), Expect = 1e-35
Identities = 86/197 (43%), Positives = 118/197 (59%), Gaps = 13/197 (6%)
Query: 5 NKGPSYGLSAEVKNKIASKYDHQAEEDLRNWIEEVTGMSIGP------NFQLGLKDGIIL 58
NKGPSYG+S EV++KI KYD + EE L WI G +G FQ+ LK+G+IL
Sbjct: 3 NKGPSYGMSREVQSKIEKKYDEELEERLVEWIIVQCGPDVGRPDRGRLGFQVWLKNGVIL 62
Query: 59 CELINKLQPGSVKKV----NESSLNWPQLENIGNFIKAIQAYGMKPHDIFEANDLFENGN 114
+L+N L P K V N S+ + Q+E + F+KA + YG+ D+F+ DLFE +
Sbjct: 63 SKLVNSLYPDGSKPVKVPENPPSMVFKQMEQVAQFLKAAEDYGVIKTDMFQTVDLFEGKD 122
Query: 115 MTQVQTTLVALAGLAKTKG---FHTTIDIGVKYAEKQTRRFDEGKLKAGQSVIGLQMGTN 171
M VQ TL+AL LA TK + + +K A++ R F E +L+ G+ VIGLQMG+N
Sbjct: 123 MAAVQRTLMALGSLAVTKNDGHYRGDPNWFMKKAQEHKREFTESQLQEGKHVIGLQMGSN 182
Query: 172 KCASQAGMTAYGTRRHL 188
+ ASQAGMT YG R +
Sbjct: 183 RGASQAGMTGYGRPRQI 199
Score = 32.7 bits (73), Expect = 0.46
Identities = 15/25 (60%), Positives = 19/25 (76%)
Query: 243 ISLQMGTNKVASQKGMSVYGLGRQV 267
I LQMG+N+ ASQ GM+ YG RQ+
Sbjct: 175 IGLQMGSNRGASQAGMTGYGRPRQI 199
>gi|4507357 transgelin 2 [Homo sapiens]
Length = 199
Score = 146 bits (369), Expect = 2e-35
Identities = 85/196 (43%), Positives = 116/196 (59%), Gaps = 12/196 (6%)
Query: 5 NKGPSYGLSAEVKNKIASKYDHQAEEDLRNWIEEVTGMSIG------PNFQLGLKDGIIL 58
N+GP+YGLS EV+ KI +YD E+ L WI +G NFQ LKDG +L
Sbjct: 3 NRGPAYGLSREVQQKIEKQYDADLEQILIQWITTQCRKDVGRPQPGRENFQNWLKDGTVL 62
Query: 59 CELINKLQP---GSVKKVNESSLNWPQLENIGNFIKAIQAYGMKPHDIFEANDLFENGNM 115
CELIN L P VKK+ S++ + Q+E I F++A + YG+ DIF+ DL+E NM
Sbjct: 63 CELINALYPEGQAPVKKIQASTMAFKQMEQISQFLQAAERYGINTTDIFQTVDLWEGKNM 122
Query: 116 TQVQTTLVALAGLAKTKG---FHTTIDIGVKYAEKQTRRFDEGKLKAGQSVIGLQMGTNK 172
VQ TL+ L GLA + F + K +++ R F + +L+ G++VIGLQMGTN+
Sbjct: 123 ACVQRTLMNLGGLAVARDDGLFSGDPNWFPKKSKENPRNFSDNQLQEGKNVIGLQMGTNR 182
Query: 173 CASQAGMTAYGTRRHL 188
ASQAGMT YG R +
Sbjct: 183 GASQAGMTGYGMPRQI 198
>gi|56549135 transgelin 3 [Homo sapiens]
Length = 199
Score = 145 bits (367), Expect = 4e-35
Identities = 88/203 (43%), Positives = 119/203 (58%), Gaps = 26/203 (12%)
Query: 5 NKGPSYGLSAEVKNKIASKYDHQAEEDLRNWI-----EEVTGMSIG-PNFQLGLKDGIIL 58
N+GPSYGLS EV+ KI KYD E L +WI E++ G +FQ L DG +L
Sbjct: 3 NRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGTVL 62
Query: 59 CELINKLQPGS---VKKVNESSLNWPQLENIGNFIKAIQAYGMKPHDIFEANDLFENGNM 115
C+LIN L P + K++ES + + Q+E I F+KA + YG++ DIF+ DL+E +M
Sbjct: 63 CKLINSLYPPGQEPIPKISESKMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGKDM 122
Query: 116 TQVQTTLVALAGLAKTKG----------FHTTIDIGVKYAEKQTRRFDEGKLKAGQSVIG 165
VQ TL+AL +A TK FH + A++ R F E +L+ GQ+VIG
Sbjct: 123 AAVQRTLMALGSVAVTKDDGCYRGEPSWFH-------RKAQQNRRGFSEEQLRQGQNVIG 175
Query: 166 LQMGTNKCASQAGMTAYGTRRHL 188
LQMG+NK ASQAGMT YG R +
Sbjct: 176 LQMGSNKGASQAGMTGYGMPRQI 198
Score = 35.8 bits (81), Expect = 0.054
Identities = 16/27 (59%), Positives = 21/27 (77%)
Query: 241 STISLQMGTNKVASQKGMSVYGLGRQV 267
+ I LQMG+NK ASQ GM+ YG+ RQ+
Sbjct: 172 NVIGLQMGSNKGASQAGMTGYGMPRQI 198
>gi|56549139 transgelin 3 [Homo sapiens]
Length = 199
Score = 145 bits (367), Expect = 4e-35
Identities = 88/203 (43%), Positives = 119/203 (58%), Gaps = 26/203 (12%)
Query: 5 NKGPSYGLSAEVKNKIASKYDHQAEEDLRNWI-----EEVTGMSIG-PNFQLGLKDGIIL 58
N+GPSYGLS EV+ KI KYD E L +WI E++ G +FQ L DG +L
Sbjct: 3 NRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGTVL 62
Query: 59 CELINKLQPGS---VKKVNESSLNWPQLENIGNFIKAIQAYGMKPHDIFEANDLFENGNM 115
C+LIN L P + K++ES + + Q+E I F+KA + YG++ DIF+ DL+E +M
Sbjct: 63 CKLINSLYPPGQEPIPKISESKMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGKDM 122
Query: 116 TQVQTTLVALAGLAKTKG----------FHTTIDIGVKYAEKQTRRFDEGKLKAGQSVIG 165
VQ TL+AL +A TK FH + A++ R F E +L+ GQ+VIG
Sbjct: 123 AAVQRTLMALGSVAVTKDDGCYRGEPSWFH-------RKAQQNRRGFSEEQLRQGQNVIG 175
Query: 166 LQMGTNKCASQAGMTAYGTRRHL 188
LQMG+NK ASQAGMT YG R +
Sbjct: 176 LQMGSNKGASQAGMTGYGMPRQI 198
Score = 35.8 bits (81), Expect = 0.054
Identities = 16/27 (59%), Positives = 21/27 (77%)
Query: 241 STISLQMGTNKVASQKGMSVYGLGRQV 267
+ I LQMG+NK ASQ GM+ YG+ RQ+
Sbjct: 172 NVIGLQMGSNKGASQAGMTGYGMPRQI 198
>gi|56549137 transgelin 3 [Homo sapiens]
Length = 199
Score = 145 bits (367), Expect = 4e-35
Identities = 88/203 (43%), Positives = 119/203 (58%), Gaps = 26/203 (12%)
Query: 5 NKGPSYGLSAEVKNKIASKYDHQAEEDLRNWI-----EEVTGMSIG-PNFQLGLKDGIIL 58
N+GPSYGLS EV+ KI KYD E L +WI E++ G +FQ L DG +L
Sbjct: 3 NRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGTVL 62
Query: 59 CELINKLQPGS---VKKVNESSLNWPQLENIGNFIKAIQAYGMKPHDIFEANDLFENGNM 115
C+LIN L P + K++ES + + Q+E I F+KA + YG++ DIF+ DL+E +M
Sbjct: 63 CKLINSLYPPGQEPIPKISESKMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGKDM 122
Query: 116 TQVQTTLVALAGLAKTKG----------FHTTIDIGVKYAEKQTRRFDEGKLKAGQSVIG 165
VQ TL+AL +A TK FH + A++ R F E +L+ GQ+VIG
Sbjct: 123 AAVQRTLMALGSVAVTKDDGCYRGEPSWFH-------RKAQQNRRGFSEEQLRQGQNVIG 175
Query: 166 LQMGTNKCASQAGMTAYGTRRHL 188
LQMG+NK ASQAGMT YG R +
Sbjct: 176 LQMGSNKGASQAGMTGYGMPRQI 198
Score = 35.8 bits (81), Expect = 0.054
Identities = 16/27 (59%), Positives = 21/27 (77%)
Query: 241 STISLQMGTNKVASQKGMSVYGLGRQV 267
+ I LQMG+NK ASQ GM+ YG+ RQ+
Sbjct: 172 NVIGLQMGSNKGASQAGMTGYGMPRQI 198
>gi|163310745 LIM and calponin homology domains 1 isoform c [Homo
sapiens]
Length = 1056
Score = 73.2 bits (178), Expect = 3e-13
Identities = 36/94 (38%), Positives = 59/94 (62%), Gaps = 1/94 (1%)
Query: 28 AEEDLRNWIEEVTGMSIGP-NFQLGLKDGIILCELINKLQPGSVKKVNESSLNWPQLENI 86
A + + WIE+VTG S G +F+ GL++GI+LCEL+N ++PG VKK+N L+NI
Sbjct: 23 AFSEAQKWIEQVTGRSFGDKDFRTGLENGILLCELLNAIKPGLVKKINRLPTPIAGLDNI 82
Query: 87 GNFIKAIQAYGMKPHDIFEANDLFENGNMTQVQT 120
F++ + G+K +F+ +DL + N V++
Sbjct: 83 ILFLRGCKELGLKESQLFDPSDLQDTSNRVTVKS 116
>gi|163310743 LIM and calponin homology domains 1 isoform b [Homo
sapiens]
Length = 1057
Score = 73.2 bits (178), Expect = 3e-13
Identities = 36/94 (38%), Positives = 59/94 (62%), Gaps = 1/94 (1%)
Query: 28 AEEDLRNWIEEVTGMSIGP-NFQLGLKDGIILCELINKLQPGSVKKVNESSLNWPQLENI 86
A + + WIE+VTG S G +F+ GL++GI+LCEL+N ++PG VKK+N L+NI
Sbjct: 23 AFSEAQKWIEQVTGRSFGDKDFRTGLENGILLCELLNAIKPGLVKKINRLPTPIAGLDNI 82
Query: 87 GNFIKAIQAYGMKPHDIFEANDLFENGNMTQVQT 120
F++ + G+K +F+ +DL + N V++
Sbjct: 83 ILFLRGCKELGLKESQLFDPSDLQDTSNRVTVKS 116
>gi|163310741 LIM and calponin homology domains 1 isoform a [Homo
sapiens]
Length = 1083
Score = 73.2 bits (178), Expect = 3e-13
Identities = 36/94 (38%), Positives = 59/94 (62%), Gaps = 1/94 (1%)
Query: 28 AEEDLRNWIEEVTGMSIGP-NFQLGLKDGIILCELINKLQPGSVKKVNESSLNWPQLENI 86
A + + WIE+VTG S G +F+ GL++GI+LCEL+N ++PG VKK+N L+NI
Sbjct: 23 AFSEAQKWIEQVTGRSFGDKDFRTGLENGILLCELLNAIKPGLVKKINRLPTPIAGLDNI 82
Query: 87 GNFIKAIQAYGMKPHDIFEANDLFENGNMTQVQT 120
F++ + G+K +F+ +DL + N V++
Sbjct: 83 ILFLRGCKELGLKESQLFDPSDLQDTSNRVTVKS 116
>gi|33598968 LIM domain only 7 isoform 1 [Homo sapiens]
Length = 1349
Score = 62.4 bits (150), Expect = 5e-10
Identities = 29/73 (39%), Positives = 46/73 (63%)
Query: 47 NFQLGLKDGIILCELINKLQPGSVKKVNESSLNWPQLENIGNFIKAIQAYGMKPHDIFEA 106
+F+ L++G++LC+LINKL+PG +KK+N S L+NI F+KA + G+K +F
Sbjct: 86 DFRASLENGVLLCDLINKLKPGVIKKINRLSTPIAGLDNINVFLKACEQIGLKEAQLFHP 145
Query: 107 NDLFENGNMTQVQ 119
DL + N V+
Sbjct: 146 GDLQDLSNRVTVK 158
>gi|22027528 PAK-interacting exchange factor beta isoform b [Homo
sapiens]
Length = 782
Score = 50.4 bits (119), Expect = 2e-06
Identities = 28/78 (35%), Positives = 46/78 (58%), Gaps = 3/78 (3%)
Query: 49 QLGLKDGIILCELINKLQPGSVKKVNESSLNWPQ-LENIGNFIKAIQAYGMKPHDIFEAN 107
Q LKDG++LC L+ +L PG+++KV + + L NI F++ A + F+AN
Sbjct: 32 QASLKDGVVLCRLLERLLPGTIEKVYPEPRSESECLSNIREFLRGCGA--SLRLETFDAN 89
Query: 108 DLFENGNMTQVQTTLVAL 125
DL++ N +V ++LV L
Sbjct: 90 DLYQGQNFNKVLSSLVTL 107
>gi|22027525 Rac/Cdc42 guanine nucleotide exchange factor 6 [Homo
sapiens]
Length = 776
Score = 50.1 bits (118), Expect = 3e-06
Identities = 27/75 (36%), Positives = 47/75 (62%), Gaps = 4/75 (5%)
Query: 52 LKDGIILCELINKLQPGSVKK-VNESSLNWPQLENIGNFIKAIQAYGMKPHDIFEANDLF 110
LK+G++LC+LIN+L PGSV+K + + NI +F+K + +IF+ +DL+
Sbjct: 35 LKNGVVLCKLINRLMPGSVEKFCLDPQTEADCINNINDFLKGCATLQV---EIFDPDDLY 91
Query: 111 ENGNMTQVQTTLVAL 125
N ++V +TL+A+
Sbjct: 92 SGVNFSKVLSTLLAV 106
>gi|154091020 leucine-rich repeats and calponin homology (CH) domain
containing 2 [Homo sapiens]
Length = 765
Score = 49.3 bits (116), Expect = 5e-06
Identities = 34/127 (26%), Positives = 58/127 (45%), Gaps = 11/127 (8%)
Query: 23 KYDHQAEE-----DLRNWIEEVTGMSIGPNFQLGLKDGIILCELINKLQPGSVKKVNESS 77
K +H EE LRN +E + + + L DG++LC L N ++P SV ++ S
Sbjct: 638 KMEHLREEREQIRQLRNNLESRLKVILPDDIGAALMDGVVLCHLANHIRPRSVASIHVPS 697
Query: 78 LNWPQL------ENIGNFIKAIQAYGMKPHDIFEANDLFENGNMTQVQTTLVALAGLAKT 131
P+L N+ NF+ A + G+ + + + E + +V T+ AL L T
Sbjct: 698 PAVPKLSMAKCRRNVENFLDACKKLGVSQERLCLPHHILEERGLVKVGVTVQALLELPTT 757
Query: 132 KGFHTTI 138
K ++
Sbjct: 758 KASQLSV 764
>gi|7108367 vav 1 guanine nucleotide exchange factor [Homo sapiens]
Length = 845
Score = 45.8 bits (107), Expect = 5e-05
Identities = 30/82 (36%), Positives = 50/82 (60%), Gaps = 9/82 (10%)
Query: 52 LKDGIILCELINKLQPGSVKKVNESSLNWPQ------LENIGNFIK-AIQAYGMKPHDIF 104
L+DG++LC+L+N L P ++ + E +L PQ L+NI F+ + +G+K ++F
Sbjct: 37 LRDGVLLCQLLNNLLPHAI-NLREVNLR-PQMSQFLCLKNIRTFLSTCCEKFGLKRSELF 94
Query: 105 EANDLFENGNMTQVQTTLVALA 126
EA DLF+ + +V TL AL+
Sbjct: 95 EAFDLFDVQDFGKVIYTLSALS 116
>gi|120432044 vav 3 guanine nucleotide exchange factor isoform 1
[Homo sapiens]
Length = 847
Score = 45.4 bits (106), Expect = 7e-05
Identities = 28/80 (35%), Positives = 49/80 (61%), Gaps = 5/80 (6%)
Query: 52 LKDGIILCELINKLQPGSV--KKVN--ESSLNWPQLENIGNFIKA-IQAYGMKPHDIFEA 106
L+DG++LC+L+N L+ S+ K++N + L+NI F+ A + +GM+ ++FEA
Sbjct: 37 LRDGVLLCQLLNNLRAHSINLKEINLRPQMSQFLCLKNIRTFLTACCETFGMRKSELFEA 96
Query: 107 NDLFENGNMTQVQTTLVALA 126
DLF+ + +V TL L+
Sbjct: 97 FDLFDVRDFGKVIETLSRLS 116
>gi|33859670 leucine-rich repeats and calponin homology (CH) domain
containing 1 [Homo sapiens]
Length = 728
Score = 45.4 bits (106), Expect = 7e-05
Identities = 26/88 (29%), Positives = 45/88 (51%), Gaps = 6/88 (6%)
Query: 30 EDLRNWIEEVTGMSIGPNFQLGLKDGIILCELINKLQPGSVKKVNESSLNWPQL------ 83
E LR IE +S+ + L DG++LC L+N ++P SV ++ S P+L
Sbjct: 584 EQLRESIEMRLKVSLHEDLGAALMDGVVLCHLVNHIRPRSVASIHVPSPAVPKLSMAKCR 643
Query: 84 ENIGNFIKAIQAYGMKPHDIFEANDLFE 111
N+ NF++A + G+ D+ D+ +
Sbjct: 644 RNVENFLEACRKLGVPEADLCSPCDILQ 671
>gi|166064034 PAK-interacting exchange factor beta isoform c [Homo
sapiens]
Length = 803
Score = 44.3 bits (103), Expect = 2e-04
Identities = 29/97 (29%), Positives = 47/97 (48%), Gaps = 20/97 (20%)
Query: 49 QLGLKDGIILCELINKLQPGSVKKVNESSLNWPQ-LENIGNFIKAIQAY---------GM 98
Q LKDG++LC L+ +L PG+++KV + + L NI F++ A
Sbjct: 32 QASLKDGVVLCRLLERLLPGTIEKVYPEPRSESECLSNIREFLRGCGASLRLELLFPPSQ 91
Query: 99 KPHDI----------FEANDLFENGNMTQVQTTLVAL 125
P + F+ANDL++ N +V ++LV L
Sbjct: 92 PPQHLVTTILLSASTFDANDLYQGQNFNKVLSSLVTL 128
>gi|197304715 vav 2 guanine nucleotide exchange factor isoform 1
[Homo sapiens]
Length = 878
Score = 43.9 bits (102), Expect = 2e-04
Identities = 27/89 (30%), Positives = 53/89 (59%), Gaps = 7/89 (7%)
Query: 52 LKDGIILCELINKLQPGSV--KKVN--ESSLNWPQLENIGNFIKAI-QAYGMKPHDIFEA 106
L+DG++LC+L++ L PGS+ K +N + L+NI F+K +G++ ++F+
Sbjct: 37 LRDGVLLCQLLHNLSPGSIDLKDINFRPQMSQFLCLKNIRTFLKVCHDKFGLRNSELFDP 96
Query: 107 NDLFENGNMTQVQTTL--VALAGLAKTKG 133
DLF+ + +V + + ++L +A+ KG
Sbjct: 97 FDLFDVRDFGKVISAVSRLSLHSIAQNKG 125
>gi|40549448 vav 2 guanine nucleotide exchange factor isoform 2
[Homo sapiens]
Length = 839
Score = 43.9 bits (102), Expect = 2e-04
Identities = 27/89 (30%), Positives = 53/89 (59%), Gaps = 7/89 (7%)
Query: 52 LKDGIILCELINKLQPGSV--KKVN--ESSLNWPQLENIGNFIKAI-QAYGMKPHDIFEA 106
L+DG++LC+L++ L PGS+ K +N + L+NI F+K +G++ ++F+
Sbjct: 37 LRDGVLLCQLLHNLSPGSIDLKDINFRPQMSQFLCLKNIRTFLKVCHDKFGLRNSELFDP 96
Query: 107 NDLFENGNMTQVQTTL--VALAGLAKTKG 133
DLF+ + +V + + ++L +A+ KG
Sbjct: 97 FDLFDVRDFGKVISAVSRLSLHSIAQNKG 125
>gi|30181233 leucine-rich repeats and calponin homology (CH) domain
containing 4 [Homo sapiens]
Length = 683
Score = 40.4 bits (93), Expect = 0.002
Identities = 28/100 (28%), Positives = 51/100 (51%), Gaps = 7/100 (7%)
Query: 32 LRNWIEEVTGMSIGPNFQLGLKDGIILCELINKLQPGSVKKVNESSLNWPQL------EN 85
LR +E + + L G+ILC+L N+L+P SV ++ S P+L +N
Sbjct: 544 LRQVLESRLQRPLPEDLAEALASGVILCQLANQLRPRSVPFIHVPSPAVPKLSALKARKN 603
Query: 86 IGNFIKAIQAYGMKPHDIFEANDLFENGNMTQVQTTLVAL 125
+ +F++A + G+ D+ +DL + G ++T L A+
Sbjct: 604 VESFLEACRKMGVPEADLCSPSDLLQ-GTARGLRTALEAV 642
>gi|166064036 PAK-interacting exchange factor beta isoform d [Homo
sapiens]
Length = 753
Score = 39.3 bits (90), Expect = 0.005
Identities = 22/77 (28%), Positives = 35/77 (45%), Gaps = 30/77 (38%)
Query: 49 QLGLKDGIILCELINKLQPGSVKKVNESSLNWPQLENIGNFIKAIQAYGMKPHDIFEAND 108
Q LKDG++LC L+ +L PG+++K F+AND
Sbjct: 32 QASLKDGVVLCRLLERLLPGTIEKT------------------------------FDAND 61
Query: 109 LFENGNMTQVQTTLVAL 125
L++ N +V ++LV L
Sbjct: 62 LYQGQNFNKVLSSLVTL 78
>gi|4506787 IQ motif containing GTPase activating protein 1 [Homo
sapiens]
Length = 1657
Score = 37.0 bits (84), Expect = 0.024
Identities = 26/109 (23%), Positives = 53/109 (48%), Gaps = 12/109 (11%)
Query: 30 EDLRNWIEEVTGMSIGPNFQL--GLKDGIILCELINKLQPG--SVKKVNE--------SS 77
E+ + W+E G + P +L GL++G+ L +L N P S+KK+ + +
Sbjct: 48 EEAKRWMEACLGEDLPPTTELEEGLRNGVYLAKLGNFFSPKVVSLKKIYDREQTRYKATG 107
Query: 78 LNWPQLENIGNFIKAIQAYGMKPHDIFEANDLFENGNMTQVQTTLVALA 126
L++ +N+ ++ A+ G+ E D+++ NM + + AL+
Sbjct: 108 LHFRHTDNVIQWLNAMDEIGLPKIFYPETTDIYDRKNMPRCIYCIHALS 156
>gi|28372563 growth arrest-specific 2 like 3 [Homo sapiens]
Length = 694
Score = 35.0 bits (79), Expect = 0.092
Identities = 32/123 (26%), Positives = 54/123 (43%), Gaps = 19/123 (15%)
Query: 29 EEDLRNWIEEVTGMSIGPNFQLG-LKDGIILCELINKLQPGSVKKVN-ESSLNWPQ---- 82
+EDL W+ + G+ + L L +G++LC+LI+ LQ VK N E S N+P
Sbjct: 51 QEDLSIWLSGLLGIKVKAEKLLEELDNGVLLCQLIDVLQ-NMVKTCNSEESGNFPMRKVP 109
Query: 83 ------------LENIGNFIKAIQAYGMKPHDIFEANDLFENGNMTQVQTTLVALAGLAK 130
+N NF+ + G+ +FE+ L + + QV L+ + +
Sbjct: 110 CKKDAASGSFFARDNTANFLHWCRDIGVDETYLFESEGLVLHKDPRQVYLCLLEIGRIVS 169
Query: 131 TKG 133
G
Sbjct: 170 RYG 172
>gi|21281675 growth arrest-specific 2 like 2 [Homo sapiens]
Length = 880
Score = 34.7 bits (78), Expect = 0.12
Identities = 29/130 (22%), Positives = 56/130 (43%), Gaps = 23/130 (17%)
Query: 19 KIASKYDHQAEEDLRNWIEEVTGMSI-GPNFQLGLKDGIILCELINKLQPGSVKKVNESS 77
K + +Y +EDL W+ ++ G+ I NF L+ G++LC+ N + ++ + E+
Sbjct: 25 KSSEQYLEAMKEDLAEWLRDLYGLDIDAANFLQVLETGLVLCQHANVVTDAALAFLAEAP 84
Query: 78 LNWPQL---------------------ENIGNFIK-AIQAYGMKPHDIFEANDLFENGNM 115
++ +N+ NFI+ + G++ +FE DL N+
Sbjct: 85 AQAQKIPMPRVGVSCNGAAQPGTFQARDNVSNFIQWCRKEMGIQEVLMFETEDLVLRKNV 144
Query: 116 TQVQTTLVAL 125
V L+ L
Sbjct: 145 KNVVLCLLEL 154
>gi|14249428 leucine-rich repeats and calponin homology (CH) domain
containing 3 [Homo sapiens]
Length = 712
Score = 34.7 bits (78), Expect = 0.12
Identities = 22/76 (28%), Positives = 36/76 (47%), Gaps = 6/76 (7%)
Query: 8 PSYGLSAEVKNKIASKYDHQAEEDL------RNWIEEVTGMSIGPNFQLGLKDGIILCEL 61
PS + + + I + Q EE+L R IE +S+ + L DG++LC L
Sbjct: 632 PSAAPTTDSTDSITGQNSRQREEELELIDQLRKHIEYRLKVSLPCDLGAALTDGVVLCHL 691
Query: 62 INKLQPGSVKKVNESS 77
N ++P SV ++ S
Sbjct: 692 ANHVRPRSVPSIHVPS 707
>gi|134142826 pericentriolar material 1 [Homo sapiens]
Length = 2024
Score = 31.6 bits (70), Expect = 1.0
Identities = 18/78 (23%), Positives = 39/78 (50%), Gaps = 6/78 (7%)
Query: 188 LYDPKMQTDKPFDQTTISLQMGTNKGASQAGMLAPGTRRDIYDQK------LTLQPVDNS 241
LY+ + + +KPF +T S+ + + +++ L RR +D++ PVD +
Sbjct: 1212 LYEQEGEVEKPFIKTGFSVSVEKSTSSNRKNQLDTNGRRRQFDEESLESFSSMPDPVDPT 1271
Query: 242 TISLQMGTNKVASQKGMS 259
T++ T K ++Q ++
Sbjct: 1272 TVTKTFKTRKASAQASLA 1289
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.132 0.383
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,282,993
Number of Sequences: 37866
Number of extensions: 520966
Number of successful extensions: 1048
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 26
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 946
Number of HSP's gapped (non-prelim): 61
length of query: 329
length of database: 18,247,518
effective HSP length: 103
effective length of query: 226
effective length of database: 14,347,320
effective search space: 3242494320
effective search space used: 3242494320
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.