Search of human proteins with 4502901

Search of human proteins with 4502901

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4502901 clathrin, light polypeptide isoform a [Homo sapiens]
         (211 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4502901 clathrin, light polypeptide isoform a [Homo sapiens]       423   e-119
gi|6005995 clathrin, light polypeptide isoform b [Homo sapiens]       412   e-115
gi|4502899 clathrin, light polypeptide A isoform a [Homo sapiens]     250   5e-67
gi|115527060 clathrin, light polypeptide A isoform c [Homo sapiens]   239   1e-63
gi|6005993 clathrin, light polypeptide A isoform b [Homo sapiens]     234   3e-62
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa...    42   3e-04
gi|88759339 aster-associated protein [Homo sapiens]                    42   4e-04
gi|4827046 U2 small nuclear RNA auxiliary factor 1-like 2 [Homo ...    42   5e-04
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi...    41   8e-04
gi|51317384 GLE1 RNA export mediator homolog isoform 1 [Homo sap...    40   0.001
gi|4557627 GLE1 RNA export mediator homolog isoform 2 [Homo sapi...    40   0.001
gi|14195601 protein phosphatase 1, regulatory (inhibitor) subuni...    40   0.002
gi|4505319 protein phosphatase 1, regulatory (inhibitor) subunit...    40   0.002
gi|154350244 hypothetical protein LOC79632 isoform 2 [Homo sapiens]    40   0.002
gi|154350226 hypothetical protein LOC79632 isoform 1 [Homo sapiens]    40   0.002
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap...    39   0.002
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap...    39   0.002
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap...    39   0.002
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi...    39   0.002
gi|55769533 PRKC, apoptosis, WT1, regulator [Homo sapiens]             39   0.002
gi|4505257 moesin [Homo sapiens]                                       39   0.002
gi|12711674 UPF3 regulator of nonsense transcripts homolog B iso...    39   0.002
gi|20270337 Leo1, Paf1/RNA polymerase II complex component, homo...    39   0.003
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik...    39   0.004
gi|190341068 forkhead-associated (FHA) phosphopeptide binding do...    39   0.004
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m...    38   0.005
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m...    38   0.005
gi|148746195 trichohyalin [Homo sapiens]                               38   0.005
gi|148886716 downstream of Stk11 [Homo sapiens]                        38   0.007
gi|32484979 adaptor-related protein complex 3, beta 1 subunit [H...    37   0.009

>gi|4502901 clathrin, light polypeptide isoform a [Homo sapiens]
          Length = 211

 Score =  423 bits (1087), Expect = e-119
 Identities = 211/211 (100%), Positives = 211/211 (100%)

Query: 1   MADDFGFFSSSESGAPEAAEEDPAAAFLAQQESEIAGIENDEGFGAPAGSHAAPAQPGPT 60
           MADDFGFFSSSESGAPEAAEEDPAAAFLAQQESEIAGIENDEGFGAPAGSHAAPAQPGPT
Sbjct: 1   MADDFGFFSSSESGAPEAAEEDPAAAFLAQQESEIAGIENDEGFGAPAGSHAAPAQPGPT 60

Query: 61  SGAGSEDMGTTVNGDVFQEANGPADGYAAIAQADRLTQEPESIRKWREEQRKRLQELDAA 120
           SGAGSEDMGTTVNGDVFQEANGPADGYAAIAQADRLTQEPESIRKWREEQRKRLQELDAA
Sbjct: 61  SGAGSEDMGTTVNGDVFQEANGPADGYAAIAQADRLTQEPESIRKWREEQRKRLQELDAA 120

Query: 121 SKVTEQEWREKAKKDLEEWNQRQSEQVEKNKINNRASEEAFVKESKEETPGTEWEKVAQL 180
           SKVTEQEWREKAKKDLEEWNQRQSEQVEKNKINNRASEEAFVKESKEETPGTEWEKVAQL
Sbjct: 121 SKVTEQEWREKAKKDLEEWNQRQSEQVEKNKINNRASEEAFVKESKEETPGTEWEKVAQL 180

Query: 181 CDFNPKSSKQCKDVSRLRSVLMSLKQTPLSR 211
           CDFNPKSSKQCKDVSRLRSVLMSLKQTPLSR
Sbjct: 181 CDFNPKSSKQCKDVSRLRSVLMSLKQTPLSR 211


>gi|6005995 clathrin, light polypeptide isoform b [Homo sapiens]
          Length = 229

 Score =  412 bits (1058), Expect = e-115
 Identities = 211/229 (92%), Positives = 211/229 (92%), Gaps = 18/229 (7%)

Query: 1   MADDFGFFSSSESGAPEAAEEDPAAAFLAQQESEIAGIENDEGFGAPAGSHAAPAQPGPT 60
           MADDFGFFSSSESGAPEAAEEDPAAAFLAQQESEIAGIENDEGFGAPAGSHAAPAQPGPT
Sbjct: 1   MADDFGFFSSSESGAPEAAEEDPAAAFLAQQESEIAGIENDEGFGAPAGSHAAPAQPGPT 60

Query: 61  SGAGSEDMGTTVNGDVFQEANGPADGYAAIAQADRLTQEPESIRKWREEQRKRLQELDAA 120
           SGAGSEDMGTTVNGDVFQEANGPADGYAAIAQADRLTQEPESIRKWREEQRKRLQELDAA
Sbjct: 61  SGAGSEDMGTTVNGDVFQEANGPADGYAAIAQADRLTQEPESIRKWREEQRKRLQELDAA 120

Query: 121 SKVTEQEWREKAKKDLEEWNQRQSEQVEKNKINNR------------------ASEEAFV 162
           SKVTEQEWREKAKKDLEEWNQRQSEQVEKNKINNR                  ASEEAFV
Sbjct: 121 SKVTEQEWREKAKKDLEEWNQRQSEQVEKNKINNRIADKAFYQQPDADIIGYVASEEAFV 180

Query: 163 KESKEETPGTEWEKVAQLCDFNPKSSKQCKDVSRLRSVLMSLKQTPLSR 211
           KESKEETPGTEWEKVAQLCDFNPKSSKQCKDVSRLRSVLMSLKQTPLSR
Sbjct: 181 KESKEETPGTEWEKVAQLCDFNPKSSKQCKDVSRLRSVLMSLKQTPLSR 229


>gi|4502899 clathrin, light polypeptide A isoform a [Homo sapiens]
          Length = 218

 Score =  250 bits (639), Expect = 5e-67
 Identities = 126/197 (63%), Positives = 148/197 (75%), Gaps = 1/197 (0%)

Query: 13  SGAPEAAEEDPAAAFLAQQESEIAGIENDEGFGAPAGSHAAPAQPGPTSGAGSEDMGTTV 72
           +G   A EEDPAAAFLAQQESEIAGIENDE F    G    P   G   G G + +   +
Sbjct: 21  NGVAGAGEEDPAAAFLAQQESEIAGIENDEAFAILDGGAPGPQPHGEPPG-GPDAVDGVM 79

Query: 73  NGDVFQEANGPADGYAAIAQADRLTQEPESIRKWREEQRKRLQELDAASKVTEQEWREKA 132
           NG+ +QE+NGP D YAAI+Q DRL  EPESIRKWREEQ +RL+ LDA S+  E EW+EKA
Sbjct: 80  NGEYYQESNGPTDSYAAISQVDRLQSEPESIRKWREEQMERLEALDANSRKQEAEWKEKA 139

Query: 133 KKDLEEWNQRQSEQVEKNKINNRASEEAFVKESKEETPGTEWEKVAQLCDFNPKSSKQCK 192
            K+LEEW  RQ EQ++K K NNRA+EEAFV +  E +PGTEWE+VA+LCDFNPKSSKQ K
Sbjct: 140 IKELEEWYARQDEQLQKTKANNRAAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQAK 199

Query: 193 DVSRLRSVLMSLKQTPL 209
           DVSR+RSVL+SLKQ PL
Sbjct: 200 DVSRMRSVLISLKQAPL 216


>gi|115527060 clathrin, light polypeptide A isoform c [Homo sapiens]
          Length = 236

 Score =  239 bits (610), Expect = 1e-63
 Identities = 126/215 (58%), Positives = 148/215 (68%), Gaps = 19/215 (8%)

Query: 13  SGAPEAAEEDPAAAFLAQQESEIAGIENDEGFGAPAGSHAAPAQPGPTSGAGSEDMGTTV 72
           +G   A EEDPAAAFLAQQESEIAGIENDE F    G    P   G   G G + +   +
Sbjct: 21  NGVAGAGEEDPAAAFLAQQESEIAGIENDEAFAILDGGAPGPQPHGEPPG-GPDAVDGVM 79

Query: 73  NGDVFQEANGPADGYAAIAQADRLTQEPESIRKWREEQRKRLQELDAASKVTEQEWREKA 132
           NG+ +QE+NGP D YAAI+Q DRL  EPESIRKWREEQ +RL+ LDA S+  E EW+EKA
Sbjct: 80  NGEYYQESNGPTDSYAAISQVDRLQSEPESIRKWREEQMERLEALDANSRKQEAEWKEKA 139

Query: 133 KKDLEEWNQRQSEQVEKNKINNR------------------ASEEAFVKESKEETPGTEW 174
            K+LEEW  RQ EQ++K K NNR                  A+EEAFV +  E +PGTEW
Sbjct: 140 IKELEEWYARQDEQLQKTKANNRVADEAFYKQPFADVIGYVAAEEAFVNDIDESSPGTEW 199

Query: 175 EKVAQLCDFNPKSSKQCKDVSRLRSVLMSLKQTPL 209
           E+VA+LCDFNPKSSKQ KDVSR+RSVL+SLKQ PL
Sbjct: 200 ERVARLCDFNPKSSKQAKDVSRMRSVLISLKQAPL 234


>gi|6005993 clathrin, light polypeptide A isoform b [Homo sapiens]
          Length = 248

 Score =  234 bits (598), Expect = 3e-62
 Identities = 126/227 (55%), Positives = 148/227 (65%), Gaps = 31/227 (13%)

Query: 13  SGAPEAAEEDPAAAFLAQQESEIAGIENDEGFGAPAGSHAAPAQPGPTSGAGSEDMGTTV 72
           +G   A EEDPAAAFLAQQESEIAGIENDE F    G    P   G   G G + +   +
Sbjct: 21  NGVAGAGEEDPAAAFLAQQESEIAGIENDEAFAILDGGAPGPQPHGEPPG-GPDAVDGVM 79

Query: 73  NGDVFQEANGPADGYAAIAQADRLTQEPESIRKWREEQRKRLQELDAASKVTEQEWREKA 132
           NG+ +QE+NGP D YAAI+Q DRL  EPESIRKWREEQ +RL+ LDA S+  E EW+EKA
Sbjct: 80  NGEYYQESNGPTDSYAAISQVDRLQSEPESIRKWREEQMERLEALDANSRKQEAEWKEKA 139

Query: 133 KKDLEEWNQRQSEQVEKNKINNR------------------------------ASEEAFV 162
            K+LEEW  RQ EQ++K K NNR                              A+EEAFV
Sbjct: 140 IKELEEWYARQDEQLQKTKANNRVADEAFYKQPFADVIGYVTNINHPCYSLEQAAEEAFV 199

Query: 163 KESKEETPGTEWEKVAQLCDFNPKSSKQCKDVSRLRSVLMSLKQTPL 209
            +  E +PGTEWE+VA+LCDFNPKSSKQ KDVSR+RSVL+SLKQ PL
Sbjct: 200 NDIDESSPGTEWERVARLCDFNPKSSKQAKDVSRMRSVLISLKQAPL 246


>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 750

 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 30/105 (28%), Positives = 57/105 (54%), Gaps = 12/105 (11%)

Query: 92  QADRLTQEPESIRK-----WREEQRKRLQELDAASKVTEQEWREKAK-KDLEEWNQRQSE 145
           Q D++ ++ E IR+     WR+E++ R QE +   +  E+ W+++ K ++ EE  Q Q E
Sbjct: 568 QEDKMWRQEEKIREQEEKVWRQEEKIREQE-EKRQEQEEKMWKQEEKIREQEEKIQEQEE 626

Query: 146 QVEKNKINNRASEEAFVKESKEETPGTEWEKVAQLCDFNPKSSKQ 190
           ++ + +   R  EE  + + +EE  G + EK   +C+   K  +Q
Sbjct: 627 KIREQEEKIREQEE--MTQEQEEKMGEQEEK---MCEQEEKMQEQ 666



 Score = 38.5 bits (88), Expect = 0.004
 Identities = 30/110 (27%), Positives = 57/110 (51%), Gaps = 11/110 (10%)

Query: 92  QADRLTQEPESIRKWRE---EQRKRLQELDAASKVTEQEWREKAKKDL----EEWNQRQS 144
           Q +++ ++ E I++W E   EQ ++++E +   K+ EQE + + ++++    EE  +RQ 
Sbjct: 298 QEEKMWRQEEKIQEWEEKIQEQEEKIREQE--EKIREQEEKMRRQEEMMWEKEEKMRRQE 355

Query: 145 EQV-EKNKINNRASEEAFVKESK-EETPGTEWEKVAQLCDFNPKSSKQCK 192
           E + EK +   R  E  + KE K        WEK  ++ +   K  +Q K
Sbjct: 356 EMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEK 405



 Score = 37.7 bits (86), Expect = 0.007
 Identities = 25/112 (22%), Positives = 53/112 (47%), Gaps = 7/112 (6%)

Query: 92  QADRLTQEPESIRKWRE---EQRKRLQELDAASKVTEQEWREKAKKDLEE----WNQRQS 144
           Q +++ ++ E IR+  E   EQ +  QE +      E++  E+ +K  E+    W Q + 
Sbjct: 617 QEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEK 676

Query: 145 EQVEKNKINNRASEEAFVKESKEETPGTEWEKVAQLCDFNPKSSKQCKDVSR 196
            + ++ KI  +  +    +E  +E     WE+  ++C+   K  +Q + + R
Sbjct: 677 IREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRR 728



 Score = 37.4 bits (85), Expect = 0.009
 Identities = 25/110 (22%), Positives = 56/110 (50%), Gaps = 11/110 (10%)

Query: 92  QADRLTQEPESIRK-----WREEQRKRLQE--LDAASKVTEQE--WREKAKKDLEE--WN 140
           Q +++ ++ E IR+     WR+E++ R QE       K+ EQE  W E+ +++ E+  W 
Sbjct: 515 QEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWR 574

Query: 141 QRQSEQVEKNKINNRASEEAFVKESKEETPGTEWEKVAQLCDFNPKSSKQ 190
           Q +  + ++ K+  +  +    +E ++E     W++  ++ +   K  +Q
Sbjct: 575 QEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQ 624



 Score = 36.2 bits (82), Expect = 0.021
 Identities = 27/107 (25%), Positives = 53/107 (49%), Gaps = 19/107 (17%)

Query: 92  QADRLTQEPESIRK-----WREEQRKRLQELDAASKVTEQE---WREKAKKDLEEWNQRQ 143
           Q +++ ++ E IRK     WR+E++ R QE     K+ EQE   WR++ K   +E   R+
Sbjct: 494 QKEKMHEQEEKIRKQEEKVWRQEEKIREQE----EKIREQEEKMWRQEEKIREQEEMWRE 549

Query: 144 SEQVEKNKINNRASEEAFVKESKEETPGTEWEKVAQLCDFNPKSSKQ 190
            E++ +        E+ + +E ++E     W +  ++ +   K  +Q
Sbjct: 550 EEKMHE-------QEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQ 589



 Score = 33.5 bits (75), Expect = 0.14
 Identities = 24/92 (26%), Positives = 46/92 (50%), Gaps = 7/92 (7%)

Query: 90  IAQADRLTQEPESIRKWREEQRKRLQELDAASKVTEQEW--REKAKKDLEEWNQRQSEQV 147
           I + +   QE E  + W++E++ R QE     K+ EQE   RE+ +K  E+    Q ++ 
Sbjct: 593 IREQEEKRQEQEE-KMWKQEEKIREQE----EKIQEQEEKIREQEEKIREQEEMTQEQEE 647

Query: 148 EKNKINNRASEEAFVKESKEETPGTEWEKVAQ 179
           +  +   +  E+    + +EET   + EK+ +
Sbjct: 648 KMGEQEEKMCEQEEKMQEQEETMWRQEEKIRE 679



 Score = 32.3 bits (72), Expect = 0.30
 Identities = 25/115 (21%), Positives = 53/115 (46%), Gaps = 8/115 (6%)

Query: 92  QADRLTQEPESIRK-----WREEQRKRLQELDAASKVTEQEWREKAKKDLEEWNQRQSEQ 146
           Q +++ ++ E +R+     W +E++ R QE     K  +   +E+   + EE  +RQ E 
Sbjct: 326 QEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEM 385

Query: 147 VEKNKINNRASEEAFVKESK---EETPGTEWEKVAQLCDFNPKSSKQCKDVSRLR 198
           + + +   R  EE   ++ K   +E    E EK+ +      + +K  +   ++R
Sbjct: 386 MWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIR 440



 Score = 31.2 bits (69), Expect = 0.67
 Identities = 25/109 (22%), Positives = 47/109 (43%), Gaps = 2/109 (1%)

Query: 90  IAQADRLTQEPESIRKWREEQRKRLQELDAASKVTEQEW--REKAKKDLEEWNQRQSEQV 147
           I + +   QE E IR+  + Q +  +      K+ EQE   RE+ KK   +  +   ++ 
Sbjct: 406 IREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEK 465

Query: 148 EKNKINNRASEEAFVKESKEETPGTEWEKVAQLCDFNPKSSKQCKDVSR 196
            + +   +  EE + +E K       W +  ++ +   K  KQ + V R
Sbjct: 466 IREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWR 514



 Score = 29.3 bits (64), Expect = 2.6
 Identities = 14/46 (30%), Positives = 27/46 (58%)

Query: 134 KDLEEWNQRQSEQVEKNKINNRASEEAFVKESKEETPGTEWEKVAQ 179
           K+L+  + +   QVE+N++ NR +++   K  ++E    EWE+  Q
Sbjct: 272 KELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQ 317



 Score = 28.9 bits (63), Expect = 3.3
 Identities = 18/93 (19%), Positives = 47/93 (50%), Gaps = 7/93 (7%)

Query: 92  QADRLTQEPESIRKWRE---EQRKRLQELDAA----SKVTEQEWREKAKKDLEEWNQRQS 144
           Q + + ++ E +R+  E   E+ ++++EL+       K+ EQE + + ++ + E  +RQ 
Sbjct: 368 QEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQE 427

Query: 145 EQVEKNKINNRASEEAFVKESKEETPGTEWEKV 177
           ++ +  +   +  E+      +E+    + EK+
Sbjct: 428 QEAKMWRQEEKIREQEEKIREQEKKMWRQEEKI 460



 Score = 28.1 bits (61), Expect = 5.7
 Identities = 19/80 (23%), Positives = 40/80 (50%), Gaps = 12/80 (15%)

Query: 92  QADRLTQEPESIR----KWREEQRKRLQELDAASKVTEQEWREKAK--------KDLEEW 139
           Q + + ++ E IR    K RE++ K  ++ +   +  E+ W ++ K        ++ EE 
Sbjct: 666 QEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEK 725

Query: 140 NQRQSEQVEKNKINNRASEE 159
            +RQ E++ + ++  R  EE
Sbjct: 726 MRRQEEKMWEQEVRLRQQEE 745


>gi|88759339 aster-associated protein [Homo sapiens]
          Length = 647

 Score = 42.0 bits (97), Expect = 4e-04
 Identities = 30/100 (30%), Positives = 52/100 (52%), Gaps = 16/100 (16%)

Query: 93  ADRLTQEPESIRKWRE-------EQRKRLQELDAASKVTEQEWREKAKKD----LEEWNQ 141
           A R  +  ++  KW+E       E+ ++ +E + A K  E+E   + KKD    +E+WN+
Sbjct: 506 AARKGEALQAFEKWKEKKMEYLKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVEKWNE 565

Query: 142 RQS---EQVEKNKINNRASEE--AFVKESKEETPGTEWEK 176
           ++    +Q EK KIN +  EE     K+ K++    E+EK
Sbjct: 566 KKEAFFKQKEKEKINEKRKEELKRAEKKDKDKQAINEYEK 605



 Score = 29.6 bits (65), Expect = 2.0
 Identities = 19/69 (27%), Positives = 36/69 (52%), Gaps = 8/69 (11%)

Query: 104 RKWREEQRKRLQELDAASKVTE----QEWREKAKKDLEEWNQRQSEQVEKNKINNRASEE 159
           ++  E+ +K+ +E +AA K       ++W+EK  + L+E N+++ E     K      EE
Sbjct: 491 KRLEEKNKKKTEEENAARKGEALQAFEKWKEKKMEYLKEKNRKEREYERAKK----QKEE 546

Query: 160 AFVKESKEE 168
             V E K++
Sbjct: 547 ETVAEKKKD 555


>gi|4827046 U2 small nuclear RNA auxiliary factor 1-like 2 [Homo
           sapiens]
          Length = 482

 Score = 41.6 bits (96), Expect = 5e-04
 Identities = 28/90 (31%), Positives = 46/90 (51%), Gaps = 6/90 (6%)

Query: 94  DRLTQEPESIRKWREEQRKRLQELDAASKVTEQEWREKAKKDLEEWNQRQSEQVEKNKIN 153
           ++  QE   I+K +EE  K+ QE +   K+ EQ W E+ +K+ EE  Q++ E+ EK +  
Sbjct: 79  EQKAQEEFRIKKEKEEAAKKRQE-EQERKLKEQ-WEEQQRKEREEEEQKRQEKKEKEEAL 136

Query: 154 NRASEEAFVKESKEETPGTEWEKVAQLCDF 183
            +  ++A      E   GT W+      DF
Sbjct: 137 QKMLDQA----ENELENGTTWQNPEPPVDF 162



 Score = 30.8 bits (68), Expect = 0.88
 Identities = 25/71 (35%), Positives = 34/71 (47%), Gaps = 7/71 (9%)

Query: 105 KWREEQRKRLQE--LDAASKVTEQ-----EWREKAKKDLEEWNQRQSEQVEKNKINNRAS 157
           K  E +R+RL E  L    K  E+     E  E AKK  EE  ++  EQ E+ +   R  
Sbjct: 62  KLLERERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREE 121

Query: 158 EEAFVKESKEE 168
           EE   +E KE+
Sbjct: 122 EEQKRQEKKEK 132


>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
           sapiens]
          Length = 1031

 Score = 40.8 bits (94), Expect = 8e-04
 Identities = 24/81 (29%), Positives = 39/81 (48%), Gaps = 6/81 (7%)

Query: 94  DRLTQEPESIRKWREEQRKRLQELDAASKVTEQEWREKAKKDLEEWNQRQSEQVEKNKIN 153
           + + +  E + KWREEQRK+  E     K   +E ++  K  LE+ +  + +  E  K  
Sbjct: 158 EEMRKRKERVEKWREEQRKKAMENIGELKKEIEEMKQGKKWSLEDDDDDEDDPAEAEKEG 217

Query: 154 NRASEE------AFVKESKEE 168
           N    E      A+++E KEE
Sbjct: 218 NEMEGEELDPLDAYMEEVKEE 238


>gi|51317384 GLE1 RNA export mediator homolog isoform 1 [Homo
           sapiens]
          Length = 698

 Score = 40.0 bits (92), Expect = 0.001
 Identities = 37/144 (25%), Positives = 66/144 (45%), Gaps = 23/144 (15%)

Query: 48  AGSHAAPAQPGPTSGAGSEDMGTTVNGDVFQEANG-PADGYAAIAQADRLTQEPESIRKW 106
           A S  +PA P   +G   +D        V Q + G   +G   + +     +  E +R W
Sbjct: 91  ASSAFSPASPATPNGTKGKDESQHTESMVLQSSRGIKVEGCVRMYELVHRMKGTEGLRLW 150

Query: 107 REEQRKRLQEL-DAASKVTEQ--EWRE----KAKKDLEEWNQRQSEQV----EKNKINN- 154
           +EEQ +++Q L + AS+  ++  EW+E    K  +DL E  ++ S +     EK K  + 
Sbjct: 151 QEEQERKVQALSEMASEQLKRFDEWKELKQHKEFQDLREVMEKSSREALGHQEKLKAEHR 210

Query: 155 ----------RASEEAFVKESKEE 168
                     R +E+  VK++++E
Sbjct: 211 HRAKILNLKLREAEQQRVKQAEQE 234


>gi|4557627 GLE1 RNA export mediator homolog isoform 2 [Homo
           sapiens]
          Length = 659

 Score = 40.0 bits (92), Expect = 0.001
 Identities = 37/144 (25%), Positives = 66/144 (45%), Gaps = 23/144 (15%)

Query: 48  AGSHAAPAQPGPTSGAGSEDMGTTVNGDVFQEANG-PADGYAAIAQADRLTQEPESIRKW 106
           A S  +PA P   +G   +D        V Q + G   +G   + +     +  E +R W
Sbjct: 91  ASSAFSPASPATPNGTKGKDESQHTESMVLQSSRGIKVEGCVRMYELVHRMKGTEGLRLW 150

Query: 107 REEQRKRLQEL-DAASKVTEQ--EWRE----KAKKDLEEWNQRQSEQV----EKNKINN- 154
           +EEQ +++Q L + AS+  ++  EW+E    K  +DL E  ++ S +     EK K  + 
Sbjct: 151 QEEQERKVQALSEMASEQLKRFDEWKELKQHKEFQDLREVMEKSSREALGHQEKLKAEHR 210

Query: 155 ----------RASEEAFVKESKEE 168
                     R +E+  VK++++E
Sbjct: 211 HRAKILNLKLREAEQQRVKQAEQE 234


>gi|14195601 protein phosphatase 1, regulatory (inhibitor) subunit
           12B isoform b [Homo sapiens]
          Length = 998

 Score = 39.7 bits (91), Expect = 0.002
 Identities = 25/83 (30%), Positives = 44/83 (53%), Gaps = 2/83 (2%)

Query: 96  LTQEPESIRKWREEQRKRLQELDAASKVTEQEWREKAKKDLEEWNQRQSEQVEKNKINNR 155
           L Q+ +++ +  +E R +L E D  SK+    ++ K K   EE   +  E  E+NK ++ 
Sbjct: 300 LLQKKQNVLRSEKETRNKLIESDLNSKIQSGFFKNKEKMLYEEETPKSQEMEEENKESSS 359

Query: 156 ASEEAFVKESKEETPGTEWEKVA 178
           +S E   +E ++E   +E EK A
Sbjct: 360 SSSEE--EEGEDEASESETEKEA 380


>gi|4505319 protein phosphatase 1, regulatory (inhibitor) subunit
           12B isoform a [Homo sapiens]
          Length = 982

 Score = 39.7 bits (91), Expect = 0.002
 Identities = 25/83 (30%), Positives = 44/83 (53%), Gaps = 2/83 (2%)

Query: 96  LTQEPESIRKWREEQRKRLQELDAASKVTEQEWREKAKKDLEEWNQRQSEQVEKNKINNR 155
           L Q+ +++ +  +E R +L E D  SK+    ++ K K   EE   +  E  E+NK ++ 
Sbjct: 300 LLQKKQNVLRSEKETRNKLIESDLNSKIQSGFFKNKEKMLYEEETPKSQEMEEENKESSS 359

Query: 156 ASEEAFVKESKEETPGTEWEKVA 178
           +S E   +E ++E   +E EK A
Sbjct: 360 SSSEE--EEGEDEASESETEKEA 380


>gi|154350244 hypothetical protein LOC79632 isoform 2 [Homo sapiens]
          Length = 971

 Score = 39.7 bits (91), Expect = 0.002
 Identities = 25/85 (29%), Positives = 45/85 (52%), Gaps = 1/85 (1%)

Query: 92  QADRLTQEPESIRKWREEQRKRLQELDAASKVTEQEWREKAKKDLE-EWNQRQSEQVEKN 150
           +  RLTQE E + +  +++ K L+E    +  T +E +EK ++ LE    Q+ S +++  
Sbjct: 605 ERQRLTQELEELEEQHQQRHKSLKEAHVLAFQTMEEEKEKEQRALENHLQQKHSAELQSL 664

Query: 151 KINNRASEEAFVKESKEETPGTEWE 175
           K  +R S E F  E ++E     +E
Sbjct: 665 KDAHRESMEGFRIEMEQELQTLRFE 689



 Score = 27.7 bits (60), Expect = 7.4
 Identities = 16/55 (29%), Positives = 35/55 (63%), Gaps = 5/55 (9%)

Query: 108 EEQRKRLQELDA---ASKVTEQEWREKAKKDLEEWNQRQSEQVEKNKINNRASEE 159
           EEQ++++ EL+     +K T+QE+ E+  K+L+  ++ + E  + N+ +++  EE
Sbjct: 313 EEQKQQILELEKKVNEAKRTQQEYYERELKNLQ--SRLEEEVTQLNEAHSKTLEE 365


>gi|154350226 hypothetical protein LOC79632 isoform 1 [Homo sapiens]
          Length = 1140

 Score = 39.7 bits (91), Expect = 0.002
 Identities = 25/85 (29%), Positives = 45/85 (52%), Gaps = 1/85 (1%)

Query: 92  QADRLTQEPESIRKWREEQRKRLQELDAASKVTEQEWREKAKKDLE-EWNQRQSEQVEKN 150
           +  RLTQE E + +  +++ K L+E    +  T +E +EK ++ LE    Q+ S +++  
Sbjct: 725 ERQRLTQELEELEEQHQQRHKSLKEAHVLAFQTMEEEKEKEQRALENHLQQKHSAELQSL 784

Query: 151 KINNRASEEAFVKESKEETPGTEWE 175
           K  +R S E F  E ++E     +E
Sbjct: 785 KDAHRESMEGFRIEMEQELQTLRFE 809



 Score = 27.7 bits (60), Expect = 7.4
 Identities = 16/55 (29%), Positives = 35/55 (63%), Gaps = 5/55 (9%)

Query: 108 EEQRKRLQELDA---ASKVTEQEWREKAKKDLEEWNQRQSEQVEKNKINNRASEE 159
           EEQ++++ EL+     +K T+QE+ E+  K+L+  ++ + E  + N+ +++  EE
Sbjct: 433 EEQKQQILELEKKVNEAKRTQQEYYERELKNLQ--SRLEEEVTQLNEAHSKTLEE 485


>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
           sapiens]
          Length = 1293

 Score = 39.3 bits (90), Expect = 0.002
 Identities = 25/95 (26%), Positives = 48/95 (50%), Gaps = 10/95 (10%)

Query: 92  QADRLTQEPESIRKWREEQRKRLQELDAASKVTEQEWREKAKKDL-------EEWNQRQS 144
           Q +   Q+ E +R+ +EE+RKR +E + A +  E+  R + ++++       EE  Q+Q 
Sbjct: 752 QEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQE 811

Query: 145 EQVEKNKINNRASEEAFVKES---KEETPGTEWEK 176
           E + + +   R  EE   +E    K+E    +W +
Sbjct: 812 EALRRLEERRREEEERRKQEELLRKQEEEAAKWAR 846



 Score = 35.4 bits (80), Expect = 0.036
 Identities = 36/148 (24%), Positives = 67/148 (45%), Gaps = 9/148 (6%)

Query: 55  AQPGPTSGAGSEDM--GTTVNGDVFQEANGPADGYAAIAQADRLTQEPESIRKWREEQRK 112
           +QP    G    D+   TT  G   ++        AA  + +R  +E E   K  EE+RK
Sbjct: 693 SQPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQER--REAEMRAKREEEERK 750

Query: 113 RLQELDAASK--VTEQEWREKAKKDLEEWNQRQSEQVEKNKINNRASEEAFVKESKEETP 170
           R +EL    +  +  Q+  E+ +++ EE  +R+ E+  + +   R  E A  ++ +EE  
Sbjct: 751 RQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQ---REQEIALRRQREEEER 807

Query: 171 GTEWEKVAQLCDFNPKSSKQCKDVSRLR 198
             + E + +L +   +  ++ K    LR
Sbjct: 808 QQQEEALRRLEERRREEEERRKQEELLR 835



 Score = 30.4 bits (67), Expect = 1.1
 Identities = 21/75 (28%), Positives = 40/75 (53%), Gaps = 14/75 (18%)

Query: 89   AIAQADRLTQEPESIRKWREEQRKRLQELDAASKVTEQEWREK------------AKKDL 136
            ++A+  +L +E E  R+ REEQR++ +EL  A +  +Q+ ++K              K L
Sbjct: 939  SLAEIQKLEEERE--RQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSL 996

Query: 137  EEWNQRQSEQVEKNK 151
             E  Q ++ Q++K +
Sbjct: 997  LEIQQEEARQMQKQQ 1011



 Score = 28.9 bits (63), Expect = 3.3
 Identities = 14/55 (25%), Positives = 29/55 (52%)

Query: 92  QADRLTQEPESIRKWREEQRKRLQELDAASKVTEQEWREKAKKDLEEWNQRQSEQ 146
           + +RL  E E+ R   EE+ ++ +EL+   +      R++ ++ L    Q+Q +Q
Sbjct: 856 EENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQ 910


>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
           sapiens]
          Length = 1320

 Score = 39.3 bits (90), Expect = 0.002
 Identities = 25/95 (26%), Positives = 48/95 (50%), Gaps = 10/95 (10%)

Query: 92  QADRLTQEPESIRKWREEQRKRLQELDAASKVTEQEWREKAKKDL-------EEWNQRQS 144
           Q +   Q+ E +R+ +EE+RKR +E + A +  E+  R + ++++       EE  Q+Q 
Sbjct: 779 QEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQE 838

Query: 145 EQVEKNKINNRASEEAFVKES---KEETPGTEWEK 176
           E + + +   R  EE   +E    K+E    +W +
Sbjct: 839 EALRRLEERRREEEERRKQEELLRKQEEEAAKWAR 873



 Score = 35.4 bits (80), Expect = 0.036
 Identities = 36/148 (24%), Positives = 67/148 (45%), Gaps = 9/148 (6%)

Query: 55  AQPGPTSGAGSEDM--GTTVNGDVFQEANGPADGYAAIAQADRLTQEPESIRKWREEQRK 112
           +QP    G    D+   TT  G   ++        AA  + +R  +E E   K  EE+RK
Sbjct: 720 SQPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQER--REAEMRAKREEEERK 777

Query: 113 RLQELDAASK--VTEQEWREKAKKDLEEWNQRQSEQVEKNKINNRASEEAFVKESKEETP 170
           R +EL    +  +  Q+  E+ +++ EE  +R+ E+  + +   R  E A  ++ +EE  
Sbjct: 778 RQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQ---REQEIALRRQREEEER 834

Query: 171 GTEWEKVAQLCDFNPKSSKQCKDVSRLR 198
             + E + +L +   +  ++ K    LR
Sbjct: 835 QQQEEALRRLEERRREEEERRKQEELLR 862



 Score = 30.4 bits (67), Expect = 1.1
 Identities = 21/75 (28%), Positives = 40/75 (53%), Gaps = 14/75 (18%)

Query: 89   AIAQADRLTQEPESIRKWREEQRKRLQELDAASKVTEQEWREK------------AKKDL 136
            ++A+  +L +E E  R+ REEQR++ +EL  A +  +Q+ ++K              K L
Sbjct: 966  SLAEIQKLEEERE--RQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSL 1023

Query: 137  EEWNQRQSEQVEKNK 151
             E  Q ++ Q++K +
Sbjct: 1024 LEIQQEEARQMQKQQ 1038



 Score = 28.9 bits (63), Expect = 3.3
 Identities = 14/55 (25%), Positives = 29/55 (52%)

Query: 92  QADRLTQEPESIRKWREEQRKRLQELDAASKVTEQEWREKAKKDLEEWNQRQSEQ 146
           + +RL  E E+ R   EE+ ++ +EL+   +      R++ ++ L    Q+Q +Q
Sbjct: 883 EENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQ 937


>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
           sapiens]
          Length = 1299

 Score = 39.3 bits (90), Expect = 0.002
 Identities = 25/95 (26%), Positives = 48/95 (50%), Gaps = 10/95 (10%)

Query: 92  QADRLTQEPESIRKWREEQRKRLQELDAASKVTEQEWREKAKKDL-------EEWNQRQS 144
           Q +   Q+ E +R+ +EE+RKR +E + A +  E+  R + ++++       EE  Q+Q 
Sbjct: 758 QEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQE 817

Query: 145 EQVEKNKINNRASEEAFVKES---KEETPGTEWEK 176
           E + + +   R  EE   +E    K+E    +W +
Sbjct: 818 EALRRLEERRREEEERRKQEELLRKQEEEAAKWAR 852



 Score = 35.4 bits (80), Expect = 0.036
 Identities = 36/148 (24%), Positives = 67/148 (45%), Gaps = 9/148 (6%)

Query: 55  AQPGPTSGAGSEDM--GTTVNGDVFQEANGPADGYAAIAQADRLTQEPESIRKWREEQRK 112
           +QP    G    D+   TT  G   ++        AA  + +R  +E E   K  EE+RK
Sbjct: 699 SQPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQER--REAEMRAKREEEERK 756

Query: 113 RLQELDAASK--VTEQEWREKAKKDLEEWNQRQSEQVEKNKINNRASEEAFVKESKEETP 170
           R +EL    +  +  Q+  E+ +++ EE  +R+ E+  + +   R  E A  ++ +EE  
Sbjct: 757 RQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQ---REQEIALRRQREEEER 813

Query: 171 GTEWEKVAQLCDFNPKSSKQCKDVSRLR 198
             + E + +L +   +  ++ K    LR
Sbjct: 814 QQQEEALRRLEERRREEEERRKQEELLR 841



 Score = 30.4 bits (67), Expect = 1.1
 Identities = 21/75 (28%), Positives = 40/75 (53%), Gaps = 14/75 (18%)

Query: 89   AIAQADRLTQEPESIRKWREEQRKRLQELDAASKVTEQEWREK------------AKKDL 136
            ++A+  +L +E E  R+ REEQR++ +EL  A +  +Q+ ++K              K L
Sbjct: 945  SLAEIQKLEEERE--RQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSL 1002

Query: 137  EEWNQRQSEQVEKNK 151
             E  Q ++ Q++K +
Sbjct: 1003 LEIQQEEARQMQKQQ 1017



 Score = 28.9 bits (63), Expect = 3.3
 Identities = 14/55 (25%), Positives = 29/55 (52%)

Query: 92  QADRLTQEPESIRKWREEQRKRLQELDAASKVTEQEWREKAKKDLEEWNQRQSEQ 146
           + +RL  E E+ R   EE+ ++ +EL+   +      R++ ++ L    Q+Q +Q
Sbjct: 862 EENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQ 916


>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
           sapiens]
          Length = 1299

 Score = 39.3 bits (90), Expect = 0.002
 Identities = 25/95 (26%), Positives = 48/95 (50%), Gaps = 10/95 (10%)

Query: 92  QADRLTQEPESIRKWREEQRKRLQELDAASKVTEQEWREKAKKDL-------EEWNQRQS 144
           Q +   Q+ E +R+ +EE+RKR +E + A +  E+  R + ++++       EE  Q+Q 
Sbjct: 758 QEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQE 817

Query: 145 EQVEKNKINNRASEEAFVKES---KEETPGTEWEK 176
           E + + +   R  EE   +E    K+E    +W +
Sbjct: 818 EALRRLEERRREEEERRKQEELLRKQEEEAAKWAR 852



 Score = 35.4 bits (80), Expect = 0.036
 Identities = 36/148 (24%), Positives = 67/148 (45%), Gaps = 9/148 (6%)

Query: 55  AQPGPTSGAGSEDM--GTTVNGDVFQEANGPADGYAAIAQADRLTQEPESIRKWREEQRK 112
           +QP    G    D+   TT  G   ++        AA  + +R  +E E   K  EE+RK
Sbjct: 699 SQPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQER--REAEMRAKREEEERK 756

Query: 113 RLQELDAASK--VTEQEWREKAKKDLEEWNQRQSEQVEKNKINNRASEEAFVKESKEETP 170
           R +EL    +  +  Q+  E+ +++ EE  +R+ E+  + +   R  E A  ++ +EE  
Sbjct: 757 RQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQ---REQEIALRRQREEEER 813

Query: 171 GTEWEKVAQLCDFNPKSSKQCKDVSRLR 198
             + E + +L +   +  ++ K    LR
Sbjct: 814 QQQEEALRRLEERRREEEERRKQEELLR 841



 Score = 30.4 bits (67), Expect = 1.1
 Identities = 21/75 (28%), Positives = 40/75 (53%), Gaps = 14/75 (18%)

Query: 89   AIAQADRLTQEPESIRKWREEQRKRLQELDAASKVTEQEWREK------------AKKDL 136
            ++A+  +L +E E  R+ REEQR++ +EL  A +  +Q+ ++K              K L
Sbjct: 945  SLAEIQKLEEERE--RQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSL 1002

Query: 137  EEWNQRQSEQVEKNK 151
             E  Q ++ Q++K +
Sbjct: 1003 LEIQQEEARQMQKQQ 1017



 Score = 28.9 bits (63), Expect = 3.3
 Identities = 14/55 (25%), Positives = 29/55 (52%)

Query: 92  QADRLTQEPESIRKWREEQRKRLQELDAASKVTEQEWREKAKKDLEEWNQRQSEQ 146
           + +RL  E E+ R   EE+ ++ +EL+   +      R++ ++ L    Q+Q +Q
Sbjct: 862 EENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQ 916


>gi|55769533 PRKC, apoptosis, WT1, regulator [Homo sapiens]
          Length = 340

 Score = 39.3 bits (90), Expect = 0.002
 Identities = 43/167 (25%), Positives = 65/167 (38%), Gaps = 32/167 (19%)

Query: 14  GAPEAAEEDPAAAFLAQQESEIAGIENDEGFGAPAGSHAAPAQPGP---TSGAGSEDMGT 70
           G+ +AA + PA A      +  A   N+     P G+ AAPA PGP       GS  +  
Sbjct: 45  GSSDAAGKPPAGAL----GTPAAAAANELNNNLPGGAPAAPAVPGPGGVNCAVGSAMLTR 100

Query: 71  TVNGDVFQEANGPADGYAAIAQADRLTQEPESI--------------------RKWREEQ 110
              G    E   PA   +A     R  +EP+ +                    RK RE++
Sbjct: 101 AAPGPRRSEDEPPAASASAAPPPQRDEEEPDGVPEKGKSSGPSARKGKGQIEKRKLREKR 160

Query: 111 RKR-LQELDAASKVTEQEWREKAKKDLEEWNQRQSEQVEKNKINNRA 156
           R   +  + AA  + E E  E  +K+     +R+    ++N I N A
Sbjct: 161 RSTGVVNIPAAECLDEYEDDEAGQKE----RKREDAITQQNTIQNEA 203


>gi|4505257 moesin [Homo sapiens]
          Length = 577

 Score = 39.3 bits (90), Expect = 0.002
 Identities = 20/68 (29%), Positives = 37/68 (54%)

Query: 98  QEPESIRKWREEQRKRLQELDAASKVTEQEWREKAKKDLEEWNQRQSEQVEKNKINNRAS 157
           +E E I + +EE  +RL++++  +K  +QE  E+ ++ LE   +R+  Q E  K+     
Sbjct: 335 KEKEKIEREKEELMERLKQIEEQTKKAQQELEEQTRRALELEQERKRAQSEAEKLAKERQ 394

Query: 158 EEAFVKES 165
           E    KE+
Sbjct: 395 EAEEAKEA 402



 Score = 33.1 bits (74), Expect = 0.18
 Identities = 29/132 (21%), Positives = 57/132 (43%), Gaps = 27/132 (20%)

Query: 94  DRLTQEPESIRKWR---EEQRKRLQELDAASKVTEQEWREKAKKDLEEWNQRQSEQVEKN 150
           +RL Q  E  +K +   EEQ +R  EL+   K  + E  EK  K+ +E  + +   ++ +
Sbjct: 349 ERLKQIEEQTKKAQQELEEQTRRALELEQERKRAQSE-AEKLAKERQEAEEAKEALLQAS 407

Query: 151 KINNRASEEAFVK--------------ESKEETPGTEWEKVAQLCDFNPKSSKQCKDVSR 196
           +   +  E+  ++                K+E+   EW++ AQ+           +D+ +
Sbjct: 408 RDQKKTQEQLALEMAELTARISQLEMARQKKESEAVEWQQKAQMVQ---------EDLEK 458

Query: 197 LRSVLMSLKQTP 208
            R+ L +   TP
Sbjct: 459 TRAELKTAMSTP 470


>gi|12711674 UPF3 regulator of nonsense transcripts homolog B
           isoform 2 [Homo sapiens]
          Length = 470

 Score = 39.3 bits (90), Expect = 0.002
 Identities = 21/102 (20%), Positives = 50/102 (49%), Gaps = 5/102 (4%)

Query: 92  QADRLTQEPESIRKWREEQRKRLQELDAASKVTEQEWREKAKKDLEEWNQRQSEQVEKNK 151
           + +R  Q  E  RKW+EE++++ ++++   K+     R+K K + +    ++ E+ ++ +
Sbjct: 222 EIERKRQREEERRKWKEEEKRKRKDIEKLKKIDRIPERDKLKDEPKIKLLKKPEKGDEKE 281

Query: 152 INNRASEEAFVKESKEETPGTEWEKVAQLCDFNPKSSKQCKD 193
           ++ R   +   KE+  +   +      Q C    +S  + KD
Sbjct: 282 LDKREKAKKLDKENLSDERAS-----GQSCTLPKRSDSELKD 318



 Score = 27.7 bits (60), Expect = 7.4
 Identities = 21/84 (25%), Positives = 43/84 (51%), Gaps = 14/84 (16%)

Query: 95  RLTQEPESIRKWREEQRKRLQELDAASKVTEQEWREKAK---KDLEEWNQRQSEQVEKNK 151
           R+ +E    R+ RE +RKR +E +       ++W+E+ K   KD+E     + +++++  
Sbjct: 209 RMREEKREERRRREIERKRQREEE------RRKWKEEEKRKRKDIE-----KLKKIDRIP 257

Query: 152 INNRASEEAFVKESKEETPGTEWE 175
             ++  +E  +K  K+   G E E
Sbjct: 258 ERDKLKDEPKIKLLKKPEKGDEKE 281


>gi|20270337 Leo1, Paf1/RNA polymerase II complex component, homolog
           [Homo sapiens]
          Length = 666

 Score = 38.9 bits (89), Expect = 0.003
 Identities = 42/190 (22%), Positives = 71/190 (37%), Gaps = 9/190 (4%)

Query: 1   MADDFGFFSSSESGAPEAAEEDPAAAFLAQQESEIAGIENDEGFGAPAGSHAAPAQPGPT 60
           MAD    F S      E  + D  +   + QE+  +G  N  G  +         QP   
Sbjct: 1   MADMEDLFGSDADSEAERKDSDSGSDSDSDQENAASG-SNASGSESDQDERGDSGQPSNK 59

Query: 61  S--GAGSEDMGTTVNGDVFQEANGPADGYAAIAQADRLTQEPESIRKWREEQRKRLQE-- 116
              G  SED G + +      +    +   A  ++D    +P  + +    +     E  
Sbjct: 60  ELFGDDSEDEGASHHSGSDNHSERSDNRSEASERSDHEDNDPSDVDQHSGSEAPNDDEDE 119

Query: 117 ---LDAASKVTEQEWREKAKKDLEEWNQR-QSEQVEKNKINNRASEEAFVKESKEETPGT 172
               D  S  +E E  EKA  D E+W +  +S+Q +  KI N   EE      +++   +
Sbjct: 120 GHRSDGGSHHSEAEGSEKAHSDDEKWGREDKSDQSDDEKIQNSDDEERAQGSDEDKLQNS 179

Query: 173 EWEKVAQLCD 182
           + ++  Q  D
Sbjct: 180 DDDEKMQNTD 189


>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
           protein 6 [Homo sapiens]
          Length = 724

 Score = 38.5 bits (88), Expect = 0.004
 Identities = 30/114 (26%), Positives = 57/114 (50%), Gaps = 11/114 (9%)

Query: 92  QADRLTQEPESIRKWRE---EQRKRLQELDAASKVTEQEWR----EKAKKDLEEWNQRQS 144
           Q +++ ++ E IR+  E   EQ +  QE +   K+ EQE +    E+  ++ EE  +RQ 
Sbjct: 583 QEEKIREQEEKIREQEEKIREQEEMTQEQE--EKMGEQEEKMCEQEEKMQEQEEKMRRQE 640

Query: 145 EQVEKNKINNRASEEAF--VKESKEETPGTEWEKVAQLCDFNPKSSKQCKDVSR 196
           E++ + +   R  EE     +E  +E     WE+  ++C+   K  +Q + + R
Sbjct: 641 EKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRR 694



 Score = 38.1 bits (87), Expect = 0.005
 Identities = 32/113 (28%), Positives = 57/113 (50%), Gaps = 23/113 (20%)

Query: 92  QADRLTQEPESIRK-----WREEQRKRLQELDAASKVTEQE---WREKAKKDLEEWNQRQ 143
           Q +++ ++ E IRK     WR+E++   QE     K+ EQE   WR++ K  + E  ++ 
Sbjct: 541 QKEKIHEQEEKIRKQEEKMWRQEEKMHDQE----EKIREQEEKVWRQEEK--IREQEEKI 594

Query: 144 SEQVEKNKINNRASEEAFVKESKEETPGTEWEKVAQLCDFNPKSSKQCKDVSR 196
            EQ EK +      E+  + + +EE  G + EK   +C+   K  +Q + + R
Sbjct: 595 REQEEKIR------EQEEMTQEQEEKMGEQEEK---MCEQEEKMQEQEEKMRR 638



 Score = 37.0 bits (84), Expect = 0.012
 Identities = 31/103 (30%), Positives = 53/103 (51%), Gaps = 7/103 (6%)

Query: 94  DRLTQEPESIRKWREEQRKRLQELDAASKVTEQEWREKAKK--DLEEWNQRQSEQV-EKN 150
           +RL Q+ E  + WR+E++  +QE +   +  E++ RE+ +K  + EE  +RQ E + EK 
Sbjct: 353 NRLNQQQEE-KMWRQEEK--IQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKE 409

Query: 151 KINNRASEEAFVKESK-EETPGTEWEKVAQLCDFNPKSSKQCK 192
           +   R  E  + KE K        WEK  ++ +   K  +Q K
Sbjct: 410 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEK 452



 Score = 32.7 bits (73), Expect = 0.23
 Identities = 23/111 (20%), Positives = 54/111 (48%), Gaps = 13/111 (11%)

Query: 92  QADRLTQEPESIRK-----WREEQRKRLQE---LDAASKVTEQE---WREKAK-KDLEEW 139
           Q +++ ++ E +R+     W +E++ R QE    +   K+  QE   W ++ K ++LEE 
Sbjct: 387 QEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEE- 445

Query: 140 NQRQSEQVEKNKINNRASEEAFVKESKEETPGTEWEKVAQLCDFNPKSSKQ 190
              + E++ + +   +  E+   +E ++E     W +  ++ +   K  +Q
Sbjct: 446 KMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQ 496



 Score = 30.4 bits (67), Expect = 1.1
 Identities = 19/93 (20%), Positives = 47/93 (50%), Gaps = 7/93 (7%)

Query: 92  QADRLTQEPESIRKWRE---EQRKRLQELDAA----SKVTEQEWREKAKKDLEEWNQRQS 144
           Q + + ++ E +R+  E   E+ ++++EL+       K+ EQE + + ++ + E  +RQ 
Sbjct: 415 QEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQE 474

Query: 145 EQVEKNKINNRASEEAFVKESKEETPGTEWEKV 177
           ++ +  +   +  E+      +EE    + EK+
Sbjct: 475 QEAKMWRQEEKIREQEEKIREQEEKMWRQEEKI 507



 Score = 29.6 bits (65), Expect = 2.0
 Identities = 19/80 (23%), Positives = 41/80 (51%), Gaps = 12/80 (15%)

Query: 92  QADRLTQEPESIR----KWREEQRKRLQELDAASKVTEQEWREKAK--------KDLEEW 139
           Q +++ ++ E IR    K RE++ K  ++ +   +  E+ W ++ K        ++ EE 
Sbjct: 632 QEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEK 691

Query: 140 NQRQSEQVEKNKINNRASEE 159
            +RQ E++ + ++  R  EE
Sbjct: 692 MRRQEEKMWEQEVRLRQQEE 711



 Score = 29.3 bits (64), Expect = 2.6
 Identities = 14/46 (30%), Positives = 27/46 (58%)

Query: 134 KDLEEWNQRQSEQVEKNKINNRASEEAFVKESKEETPGTEWEKVAQ 179
           K+L+  + +   QVE+N++ NR +++   K  ++E    EWE+  Q
Sbjct: 333 KELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQ 378



 Score = 28.9 bits (63), Expect = 3.3
 Identities = 22/103 (21%), Positives = 44/103 (42%), Gaps = 2/103 (1%)

Query: 90  IAQADRLTQEPESIRKWREEQRKRLQELDAASKVTEQEW--REKAKKDLEEWNQRQSEQV 147
           I + +   QE E IR+  + Q +  +      K+ EQE   RE+ +K   +  +   ++ 
Sbjct: 453 IREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEK 512

Query: 148 EKNKINNRASEEAFVKESKEETPGTEWEKVAQLCDFNPKSSKQ 190
            + +   +  EE + +E K       W +  ++ +   K  KQ
Sbjct: 513 IREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQ 555


>gi|190341068 forkhead-associated (FHA) phosphopeptide binding
           domain 1 [Homo sapiens]
          Length = 1412

 Score = 38.5 bits (88), Expect = 0.004
 Identities = 35/143 (24%), Positives = 56/143 (39%), Gaps = 12/143 (8%)

Query: 44  FGAPAGSHAAPAQPGPTSGAGSEDMGTTVNGDVFQEANGPADGY-AAIAQADRLTQEPES 102
           F   +    A    G +   G  + G        Q  N   DG     A  + +TQE   
Sbjct: 641 FSGNSAVFTAGKAAGASGREGEAERGEARARGEAQSQNQATDGREGGKALEEYITQERNR 700

Query: 103 IRKWREEQRKRLQELDA---------ASKVTEQEWREKAKKDLEEWNQRQSEQVEKNKIN 153
            ++  EE+RKR+QEL++         A  +T++  + + K+ LEE   R  E  E+    
Sbjct: 701 AKETLEEERKRMQELESLLAQQKKALAKSITQE--KNRVKEALEEEQTRVQELEERLARQ 758

Query: 154 NRASEEAFVKESKEETPGTEWEK 176
               E +   E ++     E EK
Sbjct: 759 KEVLESSIAHEKRKAKEALESEK 781


>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
           member 6-like protein 6 [Homo sapiens]
          Length = 655

 Score = 38.1 bits (87), Expect = 0.005
 Identities = 26/89 (29%), Positives = 47/89 (52%), Gaps = 10/89 (11%)

Query: 95  RLTQEPESIRKWREEQRKRLQELDAASKVTEQE---WREKAK-KDLEEWNQRQSEQVEKN 150
           R  +E    + WR+E++ R Q+     K+ EQE   WR++ K ++LEE  Q Q E++   
Sbjct: 398 REQEEKRQEKMWRQEKKMREQD----EKIREQEEEMWRQEEKIRELEEMMQDQEEKL--R 451

Query: 151 KINNRASEEAFVKESKEETPGTEWEKVAQ 179
           ++  +  EE    + +EE    + EK+ +
Sbjct: 452 EVEEKMQEEEEKMQEQEEKIQRQEEKIQE 480



 Score = 37.7 bits (86), Expect = 0.007
 Identities = 29/124 (23%), Positives = 64/124 (51%), Gaps = 21/124 (16%)

Query: 92  QADRLTQEPESIRK-----WREEQRKRLQELDAASKVTEQE---WREKAK-KDLEEWNQR 142
           Q +++ ++ E IR+     WR+E++ R QE     K+ EQE   WR++ K ++ +E  Q 
Sbjct: 330 QEEKMHEQEEKIREQEDKMWRQEEKIREQE----EKIREQEEKMWRQEEKIREQDEKIQE 385

Query: 143 QSEQVEKNKINNRASEEAFVKESKEETPGTEWEKVAQLCDFNPKSSKQCKDVSRLRSVLM 202
           Q E++ +        +E  ++E +E+     W +  ++ + + K  +Q +++ R    + 
Sbjct: 386 QEEEMWR--------QEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIR 437

Query: 203 SLKQ 206
            L++
Sbjct: 438 ELEE 441



 Score = 37.0 bits (84), Expect = 0.012
 Identities = 28/111 (25%), Positives = 60/111 (54%), Gaps = 16/111 (14%)

Query: 92  QADRLTQEPESIRK-----WREEQRKRLQELDAASKVTEQE---WREKAKKDLEEWNQRQ 143
           Q +++ ++ E IR+     WR+E++ R Q+     K+ EQE   WR++ K  + E  +++
Sbjct: 351 QEEKIREQEEKIREQEEKMWRQEEKIREQD----EKIQEQEEEMWRQEEK--IREQEEKR 404

Query: 144 SEQVEKNKINNRASEEAFVKESKEETPGTEWEKVAQLCDFNPKSSKQCKDV 194
            E++ + +   R  +E  ++E +EE    E EK+ +L +      ++ ++V
Sbjct: 405 QEKMWRQEKKMREQDEK-IREQEEEMWRQE-EKIRELEEMMQDQEEKLREV 453



 Score = 32.7 bits (73), Expect = 0.23
 Identities = 28/118 (23%), Positives = 58/118 (49%), Gaps = 13/118 (11%)

Query: 92  QADRLTQEPESIRK-----WREEQR-KRLQEL--DAASKVTEQEWR----EKAKKDLEEW 139
           Q  ++ ++ E IR+     WR+E++ + L+E+  D   K+ E E +    E+  ++ EE 
Sbjct: 411 QEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEK 470

Query: 140 NQRQSEQVEKNKINNRASEEAFVKESK-EETPGTEWEKVAQLCDFNPKSSKQCKDVSR 196
            QRQ E++++ +      E+   +E K  E     W +  ++ +   K  +Q + + R
Sbjct: 471 IQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQR 528



 Score = 30.8 bits (68), Expect = 0.88
 Identities = 25/107 (23%), Positives = 52/107 (48%), Gaps = 11/107 (10%)

Query: 96  LTQEPESIRKWREEQRKRLQE---LDAASKVTEQE---WREKAKKDLEEWNQRQSEQVEK 149
           L Q+ E  + WR+E++ + QE    +   K+ EQE   WR++ K   +E   R+ E    
Sbjct: 291 LNQQQEE-KMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMW 349

Query: 150 NKINNRASEEAFVKESKEETPGTEWEKVAQLCDFNPKSSKQCKDVSR 196
            +      +E  ++E +E+     W +  ++ + + K  +Q +++ R
Sbjct: 350 RQEEKIREQEEKIREQEEKM----WRQEEKIREQDEKIQEQEEEMWR 392


>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
           member 6-like protein 6 [Homo sapiens]
          Length = 655

 Score = 38.1 bits (87), Expect = 0.005
 Identities = 26/89 (29%), Positives = 47/89 (52%), Gaps = 10/89 (11%)

Query: 95  RLTQEPESIRKWREEQRKRLQELDAASKVTEQE---WREKAK-KDLEEWNQRQSEQVEKN 150
           R  +E    + WR+E++ R Q+     K+ EQE   WR++ K ++LEE  Q Q E++   
Sbjct: 398 REQEEKRQEKMWRQEKKMREQD----EKIREQEEEMWRQEEKIRELEEMMQDQEEKL--R 451

Query: 151 KINNRASEEAFVKESKEETPGTEWEKVAQ 179
           ++  +  EE    + +EE    + EK+ +
Sbjct: 452 EVEEKMQEEEEKMQEQEEKIQRQEEKIQE 480



 Score = 37.7 bits (86), Expect = 0.007
 Identities = 29/124 (23%), Positives = 64/124 (51%), Gaps = 21/124 (16%)

Query: 92  QADRLTQEPESIRK-----WREEQRKRLQELDAASKVTEQE---WREKAK-KDLEEWNQR 142
           Q +++ ++ E IR+     WR+E++ R QE     K+ EQE   WR++ K ++ +E  Q 
Sbjct: 330 QEEKMHEQEEKIREQEDKMWRQEEKIREQE----EKIREQEEKMWRQEEKIREQDEKIQE 385

Query: 143 QSEQVEKNKINNRASEEAFVKESKEETPGTEWEKVAQLCDFNPKSSKQCKDVSRLRSVLM 202
           Q E++ +        +E  ++E +E+     W +  ++ + + K  +Q +++ R    + 
Sbjct: 386 QEEEMWR--------QEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIR 437

Query: 203 SLKQ 206
            L++
Sbjct: 438 ELEE 441



 Score = 37.0 bits (84), Expect = 0.012
 Identities = 28/111 (25%), Positives = 60/111 (54%), Gaps = 16/111 (14%)

Query: 92  QADRLTQEPESIRK-----WREEQRKRLQELDAASKVTEQE---WREKAKKDLEEWNQRQ 143
           Q +++ ++ E IR+     WR+E++ R Q+     K+ EQE   WR++ K  + E  +++
Sbjct: 351 QEEKIREQEEKIREQEEKMWRQEEKIREQD----EKIQEQEEEMWRQEEK--IREQEEKR 404

Query: 144 SEQVEKNKINNRASEEAFVKESKEETPGTEWEKVAQLCDFNPKSSKQCKDV 194
            E++ + +   R  +E  ++E +EE    E EK+ +L +      ++ ++V
Sbjct: 405 QEKMWRQEKKMREQDEK-IREQEEEMWRQE-EKIRELEEMMQDQEEKLREV 453



 Score = 32.7 bits (73), Expect = 0.23
 Identities = 28/118 (23%), Positives = 58/118 (49%), Gaps = 13/118 (11%)

Query: 92  QADRLTQEPESIRK-----WREEQR-KRLQEL--DAASKVTEQEWR----EKAKKDLEEW 139
           Q  ++ ++ E IR+     WR+E++ + L+E+  D   K+ E E +    E+  ++ EE 
Sbjct: 411 QEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEK 470

Query: 140 NQRQSEQVEKNKINNRASEEAFVKESK-EETPGTEWEKVAQLCDFNPKSSKQCKDVSR 196
            QRQ E++++ +      E+   +E K  E     W +  ++ +   K  +Q + + R
Sbjct: 471 IQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQR 528



 Score = 30.8 bits (68), Expect = 0.88
 Identities = 25/107 (23%), Positives = 52/107 (48%), Gaps = 11/107 (10%)

Query: 96  LTQEPESIRKWREEQRKRLQE---LDAASKVTEQE---WREKAKKDLEEWNQRQSEQVEK 149
           L Q+ E  + WR+E++ + QE    +   K+ EQE   WR++ K   +E   R+ E    
Sbjct: 291 LNQQQEE-KMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMW 349

Query: 150 NKINNRASEEAFVKESKEETPGTEWEKVAQLCDFNPKSSKQCKDVSR 196
            +      +E  ++E +E+     W +  ++ + + K  +Q +++ R
Sbjct: 350 RQEEKIREQEEKIREQEEKM----WRQEEKIREQDEKIQEQEEEMWR 392


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 38.1 bits (87), Expect = 0.005
 Identities = 28/106 (26%), Positives = 51/106 (48%), Gaps = 2/106 (1%)

Query: 95  RLTQEP-ESIRKWREEQRKRLQELDAASKVTEQ-EWREKAKKDLEEWNQRQSEQVEKNKI 152
           +L +EP +  R+ R+EQ + L E +  S+  E+ E R++ ++D E W QRQ  Q  + + 
Sbjct: 128 QLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERR 187

Query: 153 NNRASEEAFVKESKEETPGTEWEKVAQLCDFNPKSSKQCKDVSRLR 198
                 ++      EE P  E  +  +L +   K  ++ +   R R
Sbjct: 188 AEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRER 233



 Score = 37.0 bits (84), Expect = 0.012
 Identities = 25/102 (24%), Positives = 49/102 (48%), Gaps = 5/102 (4%)

Query: 94   DRLTQEPESIRKWREEQRKRLQELD-----AASKVTEQEWREKAKKDLEEWNQRQSEQVE 148
            DR  +E E +R+ REEQ+   QE D        KV  QE   K  +D ++  +++ +Q  
Sbjct: 1554 DRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQL 1613

Query: 149  KNKINNRASEEAFVKESKEETPGTEWEKVAQLCDFNPKSSKQ 190
            + + + +  E+  + + +EE      E+  +  +  P+  +Q
Sbjct: 1614 RQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQ 1655



 Score = 35.8 bits (81), Expect = 0.027
 Identities = 30/106 (28%), Positives = 48/106 (45%), Gaps = 7/106 (6%)

Query: 92   QADRLTQEPESIRKWREEQRKRLQELDAASKVTEQEWREKAKKDLEEWNQRQSEQVEKNK 151
            + + L QE E +   REEQ KR QE +   +  E+  R+K K+       R  +Q    K
Sbjct: 1172 EEEELQQEEEQLL--REEQEKRRQERERQYREEEELQRQKRKQ-----RYRDEDQRSDLK 1224

Query: 152  INNRASEEAFVKESKEETPGTEWEKVAQLCDFNPKSSKQCKDVSRL 197
                  +E  V+++K    G E E+  QL D   +  +  +D+  L
Sbjct: 1225 WQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHL 1270



 Score = 35.0 bits (79), Expect = 0.047
 Identities = 25/88 (28%), Positives = 43/88 (48%), Gaps = 9/88 (10%)

Query: 92   QADRLTQEPESIRKWREEQRKRLQELDAASKVTEQEWREKAKKDLEEWNQRQSEQVEKNK 151
            ++DR  +E E +R+ REEQ+ R Q+ D      +  W E+ +  LEE  QR  ++ ++  
Sbjct: 1792 ESDRKFREEEQLRQEREEQQLRPQQRDG-----KYRWEEE-QLQLEEQEQRLRQERDR-- 1843

Query: 152  INNRASEEAFVKESKEETPGTEWEKVAQ 179
               RA E+   +E         W++  Q
Sbjct: 1844 -QYRAEEQFATQEKSRREEQELWQEEEQ 1870



 Score = 34.7 bits (78), Expect = 0.061
 Identities = 22/76 (28%), Positives = 37/76 (48%), Gaps = 10/76 (13%)

Query: 92   QADRLTQEPESIRKWREEQRKRLQELDAASKVTEQEWREKAKKDLEEWNQRQSEQVEKNK 151
            + DR  +E E + + REEQ  R QE D   +  E   +E+ +K LE          E+ +
Sbjct: 1333 ETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLE----------EEQR 1382

Query: 152  INNRASEEAFVKESKE 167
            +  +  E  F+KE ++
Sbjct: 1383 LRRQERERKFLKEEQQ 1398



 Score = 33.9 bits (76), Expect = 0.10
 Identities = 22/89 (24%), Positives = 44/89 (49%), Gaps = 1/89 (1%)

Query: 92  QADRLTQEPESIRKWREEQRKRLQELDAASKVTEQEWREKAKKDLEEWNQRQSEQVEKNK 151
           Q  RL +E +  RK  EE+R++ +E     +  EQ+   + ++   E  +R+ +Q+ + +
Sbjct: 296 QQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQ 355

Query: 152 INNRASEEAFVKESKEETPGTEWEKVAQL 180
              R  E+   +E +EE    +  +  QL
Sbjct: 356 EEER-REQQLRREQEEERREQQLRREQQL 383



 Score = 33.9 bits (76), Expect = 0.10
 Identities = 24/77 (31%), Positives = 42/77 (54%), Gaps = 6/77 (7%)

Query: 94   DRLTQEPESIRKWREEQRKRLQELDAASKVTEQEWR--EKAKKDLEEWNQRQSEQVEKNK 151
            DR  +E E + +  EEQ+ R QE D   +  EQ+ R  E+ +K L+E  Q + +++E+  
Sbjct: 1666 DRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELER-- 1723

Query: 152  INNRASEEAFVKESKEE 168
                  EE   +E+++E
Sbjct: 1724 --KFREEEQLRQETEQE 1738



 Score = 33.1 bits (74), Expect = 0.18
 Identities = 30/106 (28%), Positives = 48/106 (45%), Gaps = 28/106 (26%)

Query: 92  QADRLTQEPESIRKWR---EEQRKR----------LQE--------LDAASKVTEQEWRE 130
           Q  R +QE    +KWR   EE+RKR          LQE        L    +  ++E RE
Sbjct: 860 QERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREERE 919

Query: 131 KAKKDLEEWNQRQSEQVEKNKINNRASEEAFVKESKEETPGTEWEK 176
           K ++  +E   R+ EQ+++        EE  ++E +E+    E E+
Sbjct: 920 KRRRQEQERQYREEEQLQQ-------EEEQLLREEREKRRRQERER 958



 Score = 32.3 bits (72), Expect = 0.30
 Identities = 24/82 (29%), Positives = 40/82 (48%), Gaps = 8/82 (9%)

Query: 96   LTQEPESIRKW-REEQRKRLQELDAASKVTEQEWREKAKKDLEEWNQRQSEQVEKNKINN 154
            L +EPE  R+  RE Q +  +EL    +   +E REK ++   E   R+ E+V++     
Sbjct: 1094 LREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQ----- 1148

Query: 155  RASEEAFVKESKEETPGTEWEK 176
               EE  ++E  E+    E E+
Sbjct: 1149 --EEEQLLREEPEKRRRQELER 1168



 Score = 32.0 bits (71), Expect = 0.39
 Identities = 24/77 (31%), Positives = 42/77 (54%), Gaps = 8/77 (10%)

Query: 107 REEQRKRLQELDAASKVTEQEWRE-KAKKDLEE---WNQRQSEQVEKNKINNRASEEAFV 162
           RE+Q +R QE +   +  EQE RE + K++ EE   W +R+ E+ E+++   R  +   +
Sbjct: 421 REQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKRE-EETERHEQERRKQQ---L 476

Query: 163 KESKEETPGTEWEKVAQ 179
           K  +EE     W K+ +
Sbjct: 477 KRDQEEERRERWLKLEE 493



 Score = 31.6 bits (70), Expect = 0.51
 Identities = 19/67 (28%), Positives = 34/67 (50%), Gaps = 2/67 (2%)

Query: 104 RKWREEQRKRLQELDAASKVTEQEWREK--AKKDLEEWNQRQSEQVEKNKINNRASEEAF 161
           R   EE+R+R  +L+   +  +QE RE+   ++  E   QR   Q E+ ++  R   E  
Sbjct: 478 RDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQ 537

Query: 162 VKESKEE 168
           ++  +EE
Sbjct: 538 LRREQEE 544



 Score = 31.2 bits (69), Expect = 0.67
 Identities = 23/114 (20%), Positives = 51/114 (44%)

Query: 98  QEPESIRKWREEQRKRLQELDAASKVTEQEWREKAKKDLEEWNQRQSEQVEKNKINNRAS 157
           QE    R+  E+Q++RL+      +  E+E RE+ ++  E+  +R+ ++  + +   R  
Sbjct: 284 QELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQ 343

Query: 158 EEAFVKESKEETPGTEWEKVAQLCDFNPKSSKQCKDVSRLRSVLMSLKQTPLSR 211
           EE   ++ + E      E+  +      +  +Q +   +LR      ++  L R
Sbjct: 344 EERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRR 397



 Score = 30.4 bits (67), Expect = 1.1
 Identities = 19/77 (24%), Positives = 39/77 (50%), Gaps = 3/77 (3%)

Query: 92   QADRLTQEPESIRKWREEQRKRLQELDAASKVTEQEWREKAKKDLEEWNQRQSEQVEKNK 151
            + DR  +E E   + +E +RK LQE     ++  QE   K +++ +   + + EQ+ + +
Sbjct: 1688 ERDRKFREEEQQLRRQERERKFLQE---EQQLRRQELERKFREEEQLRQETEQEQLRRQE 1744

Query: 152  INNRASEEAFVKESKEE 168
               +  EE  ++  +EE
Sbjct: 1745 RYRKILEEEQLRPEREE 1761



 Score = 30.0 bits (66), Expect = 1.5
 Identities = 25/102 (24%), Positives = 48/102 (47%), Gaps = 9/102 (8%)

Query: 95  RLTQEPESIRKWREEQRKRLQELDAASKVTEQEWREKAKKDLEEWNQRQSEQVEKNKINN 154
           RL QE    R  RE++ +R    D   K  E+  +++ K++ EE   R  +++++ ++  
Sbjct: 557 RLEQERREQRLKREQEERR----DQLLKREEERRQQRLKREQEE---RLEQRLKREEVER 609

Query: 155 RASEEAFVKESKEETPGTEWEKVAQLCDFNPKSSKQCKDVSR 196
              EE   +  K E P  E E+  QL     +  ++ + + R
Sbjct: 610 LEQEERREQRLKREEP--EEERRQQLLKSEEQEERRQQQLRR 649



 Score = 30.0 bits (66), Expect = 1.5
 Identities = 24/105 (22%), Positives = 43/105 (40%), Gaps = 26/105 (24%)

Query: 98   QEPESIRKWREEQRKRLQELDAASKVTEQEWREKAKKDLEEWNQRQ-------------- 143
            Q  E  ++ R+EQ ++ +E +   +  EQ  RE+ +K   +  +RQ              
Sbjct: 914  QREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQL 973

Query: 144  -SEQVEKNKINNR-----------ASEEAFVKESKEETPGTEWEK 176
              E+ EK +   R             EE  ++E +E+    EWE+
Sbjct: 974  LGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWER 1018



 Score = 29.6 bits (65), Expect = 2.0
 Identities = 23/83 (27%), Positives = 45/83 (54%), Gaps = 6/83 (7%)

Query: 92   QADRLTQEPESIRKWREEQ-RKRLQELDAASKVTEQEWR--EKAKKDLEE---WNQRQSE 145
            + ++L QE E  +  R+E+ RK L+E     +  EQ+ R  E+ +K  EE     +R+ +
Sbjct: 1727 EEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQ 1786

Query: 146  QVEKNKINNRASEEAFVKESKEE 168
            Q+   + + +  EE  +++ +EE
Sbjct: 1787 QLRSQESDRKFREEEQLRQEREE 1809



 Score = 28.9 bits (63), Expect = 3.3
 Identities = 29/96 (30%), Positives = 46/96 (47%), Gaps = 16/96 (16%)

Query: 96   LTQEPESIRKW-REEQRKRLQEL---------DAASKVTEQEW-REKAKKD--LEEWNQR 142
            L +EPE  R+  RE++ +  +EL         +   K   QEW R+  KKD   +E  Q 
Sbjct: 974  LGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQL 1033

Query: 143  QSEQVEKNKINNRA---SEEAFVKESKEETPGTEWE 175
              E+ EK ++  R     EE  +++ +E+  G E E
Sbjct: 1034 LREEREKRRLQERERQYREEEELQQEEEQLLGEERE 1069



 Score = 28.9 bits (63), Expect = 3.3
 Identities = 24/89 (26%), Positives = 49/89 (55%), Gaps = 8/89 (8%)

Query: 92   QADRLTQEPESI-RKWREEQRKRLQELDAASKVTEQEWREKAKKDLEEWNQRQSEQVEKN 150
            + + L QE E + R+ RE++R+  QEL+   +  E+  +E+ +   EE  +R+ +++E+ 
Sbjct: 1112 EEEELQQEEEQLLREEREKRRR--QELERQYREEEEVQQEEEQLLREEPEKRRRQELER- 1168

Query: 151  KINNRASEEAFVKESKEETPGTEWEKVAQ 179
                +  EE  +++ +E+    E EK  Q
Sbjct: 1169 ----QYREEEELQQEEEQLLREEQEKRRQ 1193



 Score = 28.9 bits (63), Expect = 3.3
 Identities = 18/68 (26%), Positives = 38/68 (55%), Gaps = 2/68 (2%)

Query: 101  ESIRKWREEQRK-RLQELDAASKVTEQEWREKAKKDLEEWNQRQSEQVEKNKINNRASEE 159
            E  RK+REE+++ R QE +      EQ+ R++  +   E  Q   E+ E+ +++ +  + 
Sbjct: 1427 ERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQER-EEQQLHRQERDR 1485

Query: 160  AFVKESKE 167
             F++E ++
Sbjct: 1486 KFLEEEQQ 1493



 Score = 28.1 bits (61), Expect = 5.7
 Identities = 22/74 (29%), Positives = 37/74 (50%), Gaps = 9/74 (12%)

Query: 104 RKWREE--QRKRLQELDAASKVTEQEWREKA-------KKDLEEWNQRQSEQVEKNKINN 154
           RK REE  Q++R ++     +  E+EWR++        +K  EE  QRQ E  E+ +   
Sbjct: 220 RKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLR 279

Query: 155 RASEEAFVKESKEE 168
           +   +   +E +EE
Sbjct: 280 KLERQELRRERQEE 293



 Score = 28.1 bits (61), Expect = 5.7
 Identities = 21/89 (23%), Positives = 42/89 (47%), Gaps = 17/89 (19%)

Query: 94  DRLTQEPESIRKWR--------------EEQRKRLQELDAASKVTEQEWREKAKKDLEEW 139
           DR+ QE E  ++WR              EE+ +R +EL    +   +  R++ +++ +E 
Sbjct: 235 DRVFQEEEE-KEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEE 293

Query: 140 NQRQSEQVEKNKINNRASEEAFVKESKEE 168
            Q+Q     + ++  +  EE   +E +EE
Sbjct: 294 EQQQQRLRREQQLRRKQEEER--REQQEE 320



 Score = 28.1 bits (61), Expect = 5.7
 Identities = 21/78 (26%), Positives = 39/78 (50%), Gaps = 8/78 (10%)

Query: 92  QADRLTQEPESIRKWREEQRKRLQELDAASKVTEQEWREKAKKDLEEWNQRQSEQVEKNK 151
           Q  R  QE    R  REE+ +RL++     ++  +   E+ +++L E  Q Q+ +  K++
Sbjct: 646 QLRREQQERREQRLKREEEEERLEQ-----RLKREHEEERREQELAEEEQEQARERIKSR 700

Query: 152 INN---RASEEAFVKESK 166
           I     +   EA  ++SK
Sbjct: 701 IPKWQWQLESEADARQSK 718



 Score = 27.7 bits (60), Expect = 7.4
 Identities = 17/68 (25%), Positives = 34/68 (50%)

Query: 92  QADRLTQEPESIRKWREEQRKRLQELDAASKVTEQEWREKAKKDLEEWNQRQSEQVEKNK 151
           Q  R  +E    R  R+E+ +RLQ+   + +   +E  E+ ++ L+   +++ EQ  + +
Sbjct: 506 QLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQ 565

Query: 152 INNRASEE 159
              R  EE
Sbjct: 566 RLKREQEE 573



 Score = 27.7 bits (60), Expect = 7.4
 Identities = 21/85 (24%), Positives = 38/85 (44%), Gaps = 7/85 (8%)

Query: 98  QEPESIRKWR----EEQRKRLQELDAASKVTEQEWREKAKKDLEEWNQRQSEQVEKNKIN 153
           +EPE  R+ +    EEQ +R Q+     +   +E R K +++ E   QR   + E+ +  
Sbjct: 623 EEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERRE 682

Query: 154 NRASE---EAFVKESKEETPGTEWE 175
              +E   E   +  K   P  +W+
Sbjct: 683 QELAEEEQEQARERIKSRIPKWQWQ 707



 Score = 27.7 bits (60), Expect = 7.4
 Identities = 21/80 (26%), Positives = 38/80 (47%), Gaps = 1/80 (1%)

Query: 98  QEPESIRKWREEQRKRLQELDAASKVTEQEWREKAKKDLEEWNQRQSEQVEKNKINN-RA 156
           +E E  R+ RE++R++ QE     +   Q+  E+  ++  E  +RQ  + +  K    + 
Sbjct: 909 EEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQ 968

Query: 157 SEEAFVKESKEETPGTEWEK 176
            EE  + E  E+    E EK
Sbjct: 969 KEEQLLGEEPEKRRRQEREK 988



 Score = 27.7 bits (60), Expect = 7.4
 Identities = 22/74 (29%), Positives = 35/74 (47%), Gaps = 10/74 (13%)

Query: 107  REEQRKRLQELDAASKVTEQEWREKAK-------KDLEEWNQRQSEQVEKNK---INNRA 156
            RE++R+R Q+ D      EQ  RE+ K       K  EE    + E+ EK +    + + 
Sbjct: 1279 REQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKF 1338

Query: 157  SEEAFVKESKEETP 170
             EE  + + +EE P
Sbjct: 1339 REEEQLLQEREEQP 1352



 Score = 27.7 bits (60), Expect = 7.4
 Identities = 21/80 (26%), Positives = 40/80 (50%), Gaps = 11/80 (13%)

Query: 98   QEPESIRKWREEQ-------RKRLQELDAASKVTEQ-EWREKAKKDLEE-WNQRQSEQVE 148
            Q+ +   +W EEQ       ++  QE D   +  EQ   +EK++++ +E W  ++ EQ  
Sbjct: 1815 QQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELW--QEEEQKR 1872

Query: 149  KNKINNRASEEAFVKESKEE 168
            + +   +  EE   ++ KEE
Sbjct: 1873 RQERERKLREEHIRRQQKEE 1892



 Score = 27.3 bits (59), Expect = 9.7
 Identities = 16/65 (24%), Positives = 32/65 (49%)

Query: 95  RLTQEPESIRKWREEQRKRLQELDAASKVTEQEWREKAKKDLEEWNQRQSEQVEKNKINN 154
           R   E E   + R ++R+R +EL    +  + + RE+A++  EE +  Q +Q  +     
Sbjct: 809 RFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQ 868

Query: 155 RASEE 159
           R  ++
Sbjct: 869 RRDQK 873



 Score = 27.3 bits (59), Expect = 9.7
 Identities = 24/87 (27%), Positives = 45/87 (51%), Gaps = 6/87 (6%)

Query: 94   DRLTQEPESI-RKWREEQRKRLQELDAASKVTEQEWREKAKKDLEEWNQRQSEQVE---K 149
            D L QE E + R+ RE  ++RLQE +   +  E+  +E+ +   EE   R+ +++E   +
Sbjct: 1024 DELQQEEEQLLREERE--KRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYR 1081

Query: 150  NKINNRASEEAFVKESKEETPGTEWEK 176
             +   +  EE  ++E  E+    E E+
Sbjct: 1082 KEEELQQEEEQLLREEPEKRRRQERER 1108


>gi|148886716 downstream of Stk11 [Homo sapiens]
          Length = 447

 Score = 37.7 bits (86), Expect = 0.007
 Identities = 36/142 (25%), Positives = 61/142 (42%), Gaps = 10/142 (7%)

Query: 10  SSESGAPEAAEEDPAAAFLAQQESEIAGIENDEGFGAPAGSHAAPAQPGPTSGAGSEDMG 69
           +S +GA + AE  P+A+  + + + +         G P G+ A P + GP SGA     G
Sbjct: 226 NSAAGATDFAEISPSASSDSGEGTSLDAGTRSTKAGGP-GAAAGPGEAGPGSGA-----G 279

Query: 70  TTVNGDVFQEANGPADGYAAIAQADRLTQEPE----SIRKWREEQRKRLQELDAASKVTE 125
           T +        +   DG +   +  +   EP     S+      +R   Q   AAS+ TE
Sbjct: 280 TVLQFLTRLRRHASLDGASPYFKVKKWKLEPSQRAASLDTRGSPKRHHFQRQRAASESTE 339

Query: 126 QEWREKAKKDLEEWNQRQSEQV 147
           QE  +  ++D  ++  R  + V
Sbjct: 340 QEEGDAPQEDFIQYIARAGDAV 361


>gi|32484979 adaptor-related protein complex 3, beta 1 subunit [Homo
           sapiens]
          Length = 1094

 Score = 37.4 bits (85), Expect = 0.009
 Identities = 40/193 (20%), Positives = 78/193 (40%), Gaps = 15/193 (7%)

Query: 15  APEAAEEDPAAAFLAQQESEI----AGIENDEGFGAPAGSHAAPAQPGPTSGAGSEDMGT 70
           A +A +E+ A  F ++ E E     +  +++   G+ +G      + G ++   SED  +
Sbjct: 663 AGKAKQENSAKKFYSESEEEEDSSDSSSDSESESGSESGEQGESGEEGDSNEDSSEDSSS 722

Query: 71  TVNGDVFQEANGPADGYAAIAQADRLTQEPESIRKWREEQRKRLQELDAASKVTEQEWRE 130
             + +  +E+       A      +   + E   K  E+ +      D +S +      E
Sbjct: 723 EQDSESGRESGLENKRTAKRNSKAKGKSDSEDGEKENEKSKTSDSSNDESSSI------E 776

Query: 131 KAKKDLEEWNQRQSEQVEKNKINNRASEEAFVKESKEETPGTEWEKVAQLCDFNPKSSKQ 190
            +  D E  ++ +SE   +     R ++E   K  ++ TP T+   +  L DFNP S+  
Sbjct: 777 DSSSDSESESEPESESESR-----RVTKEKEKKTKQDRTPLTKDVSLLDLDDFNPVSTPV 831

Query: 191 CKDVSRLRSVLMS 203
                 L   LM+
Sbjct: 832 ALPTPALSPSLMA 844


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.305    0.122    0.343 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,972,545
Number of Sequences: 37866
Number of extensions: 455649
Number of successful extensions: 4726
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 225
Number of HSP's successfully gapped in prelim test: 434
Number of HSP's that attempted gapping in prelim test: 3112
Number of HSP's gapped (non-prelim): 1784
length of query: 211
length of database: 18,247,518
effective HSP length: 98
effective length of query: 113
effective length of database: 14,536,650
effective search space: 1642641450
effective search space used: 1642641450
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.