Guide to the Human Genome
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Search of human proteins with 4502611

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4502611 cyclin A1 isoform a [Homo sapiens]
         (465 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4502611 cyclin A1 isoform a [Homo sapiens]                         942   0.0  
gi|161377468 cyclin A1 isoform b [Homo sapiens]                       935   0.0  
gi|161377472 cyclin A1 isoform c [Homo sapiens]                       847   0.0  
gi|161377470 cyclin A1 isoform c [Homo sapiens]                       847   0.0  
gi|4502613 cyclin A [Homo sapiens]                                    348   5e-96
gi|4757930 cyclin B2 [Homo sapiens]                                   184   1e-46
gi|14327896 cyclin B1 [Homo sapiens]                                  172   4e-43
gi|90669307 cyclin B3 isoform 3 [Homo sapiens]                        160   2e-39
gi|16306525 cyclin B3 isoform 1 [Homo sapiens]                        119   4e-27
gi|118572588 cyclin F [Homo sapiens]                                  112   5e-25
gi|17318559 cyclin E1 isoform 1 [Homo sapiens]                        105   7e-23
gi|17318561 cyclin E1 isoform 2 [Homo sapiens]                        105   7e-23
gi|17318565 cyclin E2 [Homo sapiens]                                  103   4e-22
gi|4502619 cyclin D3 isoform 2 [Homo sapiens]                         101   1e-21
gi|153791755 cyclin domain containing [Homo sapiens]                  100   5e-21
gi|16950655 cyclin D1 [Homo sapiens]                                   93   4e-19
gi|242247025 cyclin N-terminal domain containing 2 isoform 2 [Ho...    91   2e-18
gi|4502617 cyclin D2 [Homo sapiens]                                    88   1e-17
gi|197276674 cyclin J isoform 1 [Homo sapiens]                         78   2e-14
gi|209862835 cyclin D3 isoform 1 [Homo sapiens]                        73   6e-13
gi|40254889 cyclin J isoform 2 [Homo sapiens]                          66   8e-11
gi|197276676 cyclin J isoform 3 [Homo sapiens]                         65   1e-10
gi|40805832 cyclin G1 [Homo sapiens]                                   55   2e-07
gi|4757934 cyclin G1 [Homo sapiens]                                    55   2e-07
gi|4757936 cyclin G2 [Homo sapiens]                                    54   4e-07
gi|5802992 cyclin I [Homo sapiens]                                     46   6e-05
gi|94680985 cyclin J-like [Homo sapiens]                               46   8e-05
gi|89886237 cyclin I family, member 2 [Homo sapiens]                   45   1e-04
gi|150417989 cyclin K isoform 1 [Homo sapiens]                         40   0.003
gi|38176158 cyclin K isoform 2 [Homo sapiens]                          40   0.003

>gi|4502611 cyclin A1 isoform a [Homo sapiens]
          Length = 465

 Score =  942 bits (2434), Expect = 0.0
 Identities = 465/465 (100%), Positives = 465/465 (100%)

Query: 1   METGFPAIMYPGSFIGGWGEEYLSWEGPGLPDFVFQQQPVESEAMHCSNPKSGVVLATVA 60
           METGFPAIMYPGSFIGGWGEEYLSWEGPGLPDFVFQQQPVESEAMHCSNPKSGVVLATVA
Sbjct: 1   METGFPAIMYPGSFIGGWGEEYLSWEGPGLPDFVFQQQPVESEAMHCSNPKSGVVLATVA 60

Query: 61  RGPDACQILTRAPLGQDPPQRTVLGLLTANGQYRRTCGQGITRIRCYSGSENAFPPAGKK 120
           RGPDACQILTRAPLGQDPPQRTVLGLLTANGQYRRTCGQGITRIRCYSGSENAFPPAGKK
Sbjct: 61  RGPDACQILTRAPLGQDPPQRTVLGLLTANGQYRRTCGQGITRIRCYSGSENAFPPAGKK 120

Query: 121 ALPDCGVQEPPKQGFDIYMDELEQGDRDSCSVREGMAFEDVYEVDTGTLKSDLHFLLDFN 180
           ALPDCGVQEPPKQGFDIYMDELEQGDRDSCSVREGMAFEDVYEVDTGTLKSDLHFLLDFN
Sbjct: 121 ALPDCGVQEPPKQGFDIYMDELEQGDRDSCSVREGMAFEDVYEVDTGTLKSDLHFLLDFN 180

Query: 181 TVSPMLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDIT 240
           TVSPMLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDIT
Sbjct: 181 TVSPMLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDIT 240

Query: 241 EGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKY 300
           EGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKY
Sbjct: 241 EGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKY 300

Query: 301 EEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVR 360
           EEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVR
Sbjct: 301 EEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVR 360

Query: 361 TENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIV 420
           TENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIV
Sbjct: 361 TENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIV 420

Query: 421 PCLSELHKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLLQ 465
           PCLSELHKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLLQ
Sbjct: 421 PCLSELHKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLLQ 465


>gi|161377468 cyclin A1 isoform b [Homo sapiens]
          Length = 464

 Score =  935 bits (2417), Expect = 0.0
 Identities = 464/465 (99%), Positives = 464/465 (99%), Gaps = 1/465 (0%)

Query: 1   METGFPAIMYPGSFIGGWGEEYLSWEGPGLPDFVFQQQPVESEAMHCSNPKSGVVLATVA 60
           METGFPAIMYPGSFIGGWGEEYLSWEGPGLPDFVFQQ PVESEAMHCSNPKSGVVLATVA
Sbjct: 1   METGFPAIMYPGSFIGGWGEEYLSWEGPGLPDFVFQQ-PVESEAMHCSNPKSGVVLATVA 59

Query: 61  RGPDACQILTRAPLGQDPPQRTVLGLLTANGQYRRTCGQGITRIRCYSGSENAFPPAGKK 120
           RGPDACQILTRAPLGQDPPQRTVLGLLTANGQYRRTCGQGITRIRCYSGSENAFPPAGKK
Sbjct: 60  RGPDACQILTRAPLGQDPPQRTVLGLLTANGQYRRTCGQGITRIRCYSGSENAFPPAGKK 119

Query: 121 ALPDCGVQEPPKQGFDIYMDELEQGDRDSCSVREGMAFEDVYEVDTGTLKSDLHFLLDFN 180
           ALPDCGVQEPPKQGFDIYMDELEQGDRDSCSVREGMAFEDVYEVDTGTLKSDLHFLLDFN
Sbjct: 120 ALPDCGVQEPPKQGFDIYMDELEQGDRDSCSVREGMAFEDVYEVDTGTLKSDLHFLLDFN 179

Query: 181 TVSPMLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDIT 240
           TVSPMLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDIT
Sbjct: 180 TVSPMLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDIT 239

Query: 241 EGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKY 300
           EGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKY
Sbjct: 240 EGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKY 299

Query: 301 EEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVR 360
           EEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVR
Sbjct: 300 EEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVR 359

Query: 361 TENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIV 420
           TENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIV
Sbjct: 360 TENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIV 419

Query: 421 PCLSELHKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLLQ 465
           PCLSELHKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLLQ
Sbjct: 420 PCLSELHKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLLQ 464


>gi|161377472 cyclin A1 isoform c [Homo sapiens]
          Length = 421

 Score =  847 bits (2187), Expect = 0.0
 Identities = 421/421 (100%), Positives = 421/421 (100%)

Query: 45  MHCSNPKSGVVLATVARGPDACQILTRAPLGQDPPQRTVLGLLTANGQYRRTCGQGITRI 104
           MHCSNPKSGVVLATVARGPDACQILTRAPLGQDPPQRTVLGLLTANGQYRRTCGQGITRI
Sbjct: 1   MHCSNPKSGVVLATVARGPDACQILTRAPLGQDPPQRTVLGLLTANGQYRRTCGQGITRI 60

Query: 105 RCYSGSENAFPPAGKKALPDCGVQEPPKQGFDIYMDELEQGDRDSCSVREGMAFEDVYEV 164
           RCYSGSENAFPPAGKKALPDCGVQEPPKQGFDIYMDELEQGDRDSCSVREGMAFEDVYEV
Sbjct: 61  RCYSGSENAFPPAGKKALPDCGVQEPPKQGFDIYMDELEQGDRDSCSVREGMAFEDVYEV 120

Query: 165 DTGTLKSDLHFLLDFNTVSPMLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEI 224
           DTGTLKSDLHFLLDFNTVSPMLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEI
Sbjct: 121 DTGTLKSDLHFLLDFNTVSPMLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEI 180

Query: 225 RHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRG 284
           RHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRG
Sbjct: 181 RHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRG 240

Query: 285 KLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTT 344
           KLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTT
Sbjct: 241 KLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTT 300

Query: 345 NQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFW 404
           NQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFW
Sbjct: 301 NQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFW 360

Query: 405 PETLAAFTGYSLSEIVPCLSELHKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLL 464
           PETLAAFTGYSLSEIVPCLSELHKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLL
Sbjct: 361 PETLAAFTGYSLSEIVPCLSELHKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLL 420

Query: 465 Q 465
           Q
Sbjct: 421 Q 421


>gi|161377470 cyclin A1 isoform c [Homo sapiens]
          Length = 421

 Score =  847 bits (2187), Expect = 0.0
 Identities = 421/421 (100%), Positives = 421/421 (100%)

Query: 45  MHCSNPKSGVVLATVARGPDACQILTRAPLGQDPPQRTVLGLLTANGQYRRTCGQGITRI 104
           MHCSNPKSGVVLATVARGPDACQILTRAPLGQDPPQRTVLGLLTANGQYRRTCGQGITRI
Sbjct: 1   MHCSNPKSGVVLATVARGPDACQILTRAPLGQDPPQRTVLGLLTANGQYRRTCGQGITRI 60

Query: 105 RCYSGSENAFPPAGKKALPDCGVQEPPKQGFDIYMDELEQGDRDSCSVREGMAFEDVYEV 164
           RCYSGSENAFPPAGKKALPDCGVQEPPKQGFDIYMDELEQGDRDSCSVREGMAFEDVYEV
Sbjct: 61  RCYSGSENAFPPAGKKALPDCGVQEPPKQGFDIYMDELEQGDRDSCSVREGMAFEDVYEV 120

Query: 165 DTGTLKSDLHFLLDFNTVSPMLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEI 224
           DTGTLKSDLHFLLDFNTVSPMLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEI
Sbjct: 121 DTGTLKSDLHFLLDFNTVSPMLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEI 180

Query: 225 RHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRG 284
           RHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRG
Sbjct: 181 RHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRG 240

Query: 285 KLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTT 344
           KLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTT
Sbjct: 241 KLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTT 300

Query: 345 NQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFW 404
           NQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFW
Sbjct: 301 NQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFW 360

Query: 405 PETLAAFTGYSLSEIVPCLSELHKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLL 464
           PETLAAFTGYSLSEIVPCLSELHKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLL
Sbjct: 361 PETLAAFTGYSLSEIVPCLSELHKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLL 420

Query: 465 Q 465
           Q
Sbjct: 421 Q 421


>gi|4502613 cyclin A [Homo sapiens]
          Length = 432

 Score =  348 bits (894), Expect = 5e-96
 Identities = 190/338 (56%), Positives = 238/338 (70%), Gaps = 12/338 (3%)

Query: 135 FDIYMDELEQGDRDSCSVREGMAFEDVYEVDT-----GTLKS--DLHFLLDFNTVSPMLV 187
           F I++DE E+  +   +  + +  ED    ++     G  K    L + +D +  SP  +
Sbjct: 99  FTIHVDEAEKEAQKKPAESQKIEREDALAFNSAISLPGPRKPLVPLDYPMDGSFESPHTM 158

Query: 188 DSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTIL 247
           D S++ + E   S+      V +Y E+I+ YLRE E++ +PK  YMKKQPDIT  MR IL
Sbjct: 159 DMSIVLEDEKPVSVN----EVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAIL 214

Query: 248 VDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPE 307
           VDWLVEVGEEYKL+ ETL+LAVN++DRFLS MSVLRGKLQLVGTAAMLLASK+EEIYPPE
Sbjct: 215 VDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPE 274

Query: 308 VDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQY-LRRQGVCVRTENLAK 366
           V EFVYITDDTYTK+Q+L+MEHL+LKVL FDL  PT NQFL QY L +Q    + E+LA 
Sbjct: 275 VAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAM 334

Query: 367 YVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSEL 426
           ++ ELSL++ADP+LKYLPS+IA AAF LA YTV    WPE+L   TGY+L  + PCL +L
Sbjct: 335 FLGELSLIDADPYLKYLPSVIAGAAFHLALYTVTGQSWPESLIRKTGYTLESLKPCLMDL 394

Query: 427 HKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLL 464
           H+ YL  P   QQ+IREKYK SKY  VSL+ PP  L L
Sbjct: 395 HQTYLKAPQHAQQSIREKYKNSKYHGVSLLNPPETLNL 432


>gi|4757930 cyclin B2 [Homo sapiens]
          Length = 398

 Score =  184 bits (468), Expect = 1e-46
 Identities = 107/270 (39%), Positives = 164/270 (60%), Gaps = 5/270 (1%)

Query: 190 SLLSQSEDISSLGTDVINV-TEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILV 248
           +LL + EDI +   +   + ++Y ++IYQYLR+ E+      H++  + DI   MR ILV
Sbjct: 112 ALLCKIEDIDNEDWENPQLCSDYVKDIYQYLRQLEVLQSINPHFLDGR-DINGRMRAILV 170

Query: 249 DWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEV 308
           DWLV+V  +++L  ETLY+ V  +DRFL    V R KLQLVG  A+LLASKYEE++ P +
Sbjct: 171 DWLVQVHSKFRLLQETLYMCVGIMDRFLQVQPVSRKKLQLVGITALLLASKYEEMFSPNI 230

Query: 309 DEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYV 368
           ++FVYITD+ YT  Q+ +ME L+LK L F+L  P    FL +  +   V V    LAKY+
Sbjct: 231 EDFVYITDNAYTSSQIREMETLILKELKFELGRPLPLHFLRRASKAGEVDVEQHTLAKYL 290

Query: 369 AELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSELHK 428
            EL+L++ D  + Y PS +AAAA CL+   + +  W      +TGY+ +E++  +  + K
Sbjct: 291 MELTLIDYD-MVHYHPSKVAAAASCLSQKVLGQGKWNLKQQYYTGYTENEVLEVMQHMAK 349

Query: 429 AYLDIPHRPQQ--AIREKYKASKYLCVSLM 456
             + +     +  AI+ KY +SK L +S++
Sbjct: 350 NVVKVNENLTKFIAIKNKYASSKLLKISMI 379


>gi|14327896 cyclin B1 [Homo sapiens]
          Length = 433

 Score =  172 bits (437), Expect = 4e-43
 Identities = 96/257 (37%), Positives = 149/257 (57%), Gaps = 4/257 (1%)

Query: 202 GTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLR 261
           G D    +EY ++IY YLR+ E     +  Y+  + ++T  MR IL+DWLV+V  +++L 
Sbjct: 161 GADPNLCSEYVKDIYAYLRQLEEEQAVRPKYLLGR-EVTGNMRAILIDWLVQVQMKFRLL 219

Query: 262 AETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTK 321
            ET+Y+ V+ +DRF+    V +  LQLVG  AM +ASKYEE+YPPE+ +F ++TD+TYTK
Sbjct: 220 QETMYMTVSIIDRFMQNNCVPKKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVTDNTYTK 279

Query: 322 RQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLK 381
            Q+ +ME  +L+ L F L  P    FL +  +   V V    LAKY+ EL++L+ D  + 
Sbjct: 280 HQIRQMEMKILRALNFGLGRPLPLHFLRRASKIGEVDVEQHTLAKYLMELTMLDYD-MVH 338

Query: 382 YLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSELHKAYLDIPH--RPQQ 439
           + PS IAA AFCLA   ++   W  TL  +  Y+   ++P +  L K  + +        
Sbjct: 339 FPPSQIAAGAFCLALKILDNGEWTPTLQHYLSYTEESLLPVMQHLAKNVVMVNQGLTKHM 398

Query: 440 AIREKYKASKYLCVSLM 456
            ++ KY  SK+  +S +
Sbjct: 399 TVKNKYATSKHAKISTL 415


>gi|90669307 cyclin B3 isoform 3 [Homo sapiens]
          Length = 1395

 Score =  160 bits (406), Expect = 2e-39
 Identities = 94/254 (37%), Positives = 146/254 (57%), Gaps = 2/254 (0%)

Query: 192  LSQSEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWL 251
            ++  EDI    +D      YA+EI+ Y++E E +      YM +Q +IT  MR ILVDWL
Sbjct: 1110 ITPREDIDEDSSDPSFNPMYAKEIFSYMKEREEQFI-LTDYMNRQIEITSDMRAILVDWL 1168

Query: 252  VEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEF 311
            VEV   +++  ETLYLAV  +D +L      + KLQL+G  A ++A+K+EE   P VD+F
Sbjct: 1169 VEVQVSFEMTHETLYLAVKLVDLYLMKAVCKKDKLQLLGATAFMIAAKFEEHNSPRVDDF 1228

Query: 312  VYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAEL 371
            VYI DD Y + ++L ME  +L VL  D+ +P    FL +Y R     ++T  L++Y+ E+
Sbjct: 1229 VYICDDNYQRSEVLSMEINILNVLKCDINIPIAYHFLRRYARCIHTNMKTLTLSRYICEM 1288

Query: 372  SLLEADPFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSELHKAYL 431
            +L E   +++   S +AAA+  LA Y     +W   L  ++GYS+SE+ P + +L+K   
Sbjct: 1289 TLQEYH-YVQEKASKLAAASLLLALYMKKLGYWVPFLEHYSGYSISELHPLVRQLNKLLT 1347

Query: 432  DIPHRPQQAIREKY 445
               +   +A+  KY
Sbjct: 1348 FSSYDSLKAVYYKY 1361


>gi|16306525 cyclin B3 isoform 1 [Homo sapiens]
          Length = 291

 Score =  119 bits (299), Expect = 4e-27
 Identities = 67/188 (35%), Positives = 109/188 (57%), Gaps = 1/188 (0%)

Query: 258 YKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDD 317
           +++  ETLYLAV  +D +L      + KLQL+G  A ++A+K+EE   P VD+FVYI DD
Sbjct: 71  FEMTHETLYLAVKLVDLYLMKAVCKKDKLQLLGATAFMIAAKFEEHNSPRVDDFVYICDD 130

Query: 318 TYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELSLLEAD 377
            Y + ++L ME  +L VL  D+ +P    FL +Y R     ++T  L++Y+ E++L E  
Sbjct: 131 NYQRSEVLSMEINILNVLKCDINIPIAYHFLRRYARCIHTNMKTLTLSRYICEMTLQEYH 190

Query: 378 PFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSELHKAYLDIPHRP 437
            +++   S +AAA+  LA Y     +W   L  ++GYS+SE+ P + +L+K      +  
Sbjct: 191 -YVQEKASKLAAASLLLALYMKKLGYWVPFLEHYSGYSISELHPLVRQLNKLLTFSSYDS 249

Query: 438 QQAIREKY 445
            +A+  KY
Sbjct: 250 LKAVYYKY 257


>gi|118572588 cyclin F [Homo sapiens]
          Length = 786

 Score =  112 bits (281), Expect = 5e-25
 Identities = 91/333 (27%), Positives = 153/333 (45%), Gaps = 20/333 (6%)

Query: 128 QEPPKQGFDIYMDELEQGDRDSCSVREGMAFEDVYEVDTGTLKSDLHF---LLDFNTVSP 184
           +E  +Q  D++ +   QG    C     + +E     D       LH    L D+     
Sbjct: 200 EEKQQQAHDLFEEAAHQG----CLTSSYLLWESDRRTDVSDPGRCLHSFRKLRDYAAKGC 255

Query: 185 MLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMR 244
                SL     + + LG +V   +E   +++Q  +        K      Q  + + MR
Sbjct: 256 WEAQLSLAKACANANQLGLEVRASSEIVCQLFQASQAVS-----KQQVFSVQKGLNDTMR 310

Query: 245 TILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIY 304
            IL+DWLVEV       +  L+L V  +DR+L    V R +LQL+G A M++ +++    
Sbjct: 311 YILIDWLVEVATMKDFTSLCLHLTVECVDRYLRRRLVPRYRLQLLGIACMVICTRFISKE 370

Query: 305 PPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENL 364
              + E V++TD+TY    L++M   ++  L   + VPT   +    L    V +RT++L
Sbjct: 371 ILTIREAVWLTDNTYKYEDLVRMMGEIVSALEGKIRVPTVVDYKEVLLTLVPVELRTQHL 430

Query: 365 AKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNK-HFWPETLAAFTGYSLSEIVPCL 423
             ++ ELSLL       Y P+ +AAAA  LA  T  +   W   L   TG+S  +++PC+
Sbjct: 431 CSFLCELSLLHTS-LSAYAPARLAAAALLLARLTHGQTQPWTTQLWDLTGFSYEDLIPCV 489

Query: 424 SELHKA--YLDIPHRPQQ----AIREKYKASKY 450
             LHK   + D P   +Q    A++++++  +Y
Sbjct: 490 LSLHKKCFHDDAPKDYRQVSLTAVKQRFEDKRY 522


>gi|17318559 cyclin E1 isoform 1 [Homo sapiens]
          Length = 410

 Score =  105 bits (263), Expect = 7e-23
 Identities = 52/142 (36%), Positives = 92/142 (64%), Gaps = 1/142 (0%)

Query: 213 EEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFL 272
           EE+++ +   E  +    H++++ P +   MR IL+DWL+EV E YKL  ET YLA +F 
Sbjct: 114 EEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFF 173

Query: 273 DRFLSCM-SVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLL 331
           DR+++   +V++  LQL+G +++ +A+K EEIYPP++ +F Y+TD   +  ++L ME ++
Sbjct: 174 DRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMI 233

Query: 332 LKVLAFDLTVPTTNQFLLQYLR 353
           +K L + L+  T   +L  Y++
Sbjct: 234 MKALKWRLSPLTIVSWLNVYMQ 255


>gi|17318561 cyclin E1 isoform 2 [Homo sapiens]
          Length = 395

 Score =  105 bits (263), Expect = 7e-23
 Identities = 52/142 (36%), Positives = 92/142 (64%), Gaps = 1/142 (0%)

Query: 213 EEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFL 272
           EE+++ +   E  +    H++++ P +   MR IL+DWL+EV E YKL  ET YLA +F 
Sbjct: 99  EEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFF 158

Query: 273 DRFLSCM-SVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLL 331
           DR+++   +V++  LQL+G +++ +A+K EEIYPP++ +F Y+TD   +  ++L ME ++
Sbjct: 159 DRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMI 218

Query: 332 LKVLAFDLTVPTTNQFLLQYLR 353
           +K L + L+  T   +L  Y++
Sbjct: 219 MKALKWRLSPLTIVSWLNVYMQ 240


>gi|17318565 cyclin E2 [Homo sapiens]
          Length = 404

 Score =  103 bits (256), Expect = 4e-22
 Identities = 54/143 (37%), Positives = 88/143 (61%), Gaps = 1/143 (0%)

Query: 212 AEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNF 271
           ++E++  + + E R+    H+     D+   MR+IL+DWL+EV E Y L  ET YLA +F
Sbjct: 110 SKEVWLNMLKKESRYVHDKHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDF 169

Query: 272 LDRF-LSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHL 330
            DRF L+   + +  LQL+G  ++ +ASK EEIY P++ EF Y+TD   ++  +L+ME +
Sbjct: 170 FDRFMLTQKDINKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELI 229

Query: 331 LLKVLAFDLTVPTTNQFLLQYLR 353
           +LK L ++L   T   +L  +L+
Sbjct: 230 ILKALKWELCPVTIISWLNLFLQ 252


>gi|4502619 cyclin D3 isoform 2 [Homo sapiens]
          Length = 292

 Score =  101 bits (252), Expect = 1e-21
 Identities = 76/226 (33%), Positives = 112/226 (49%), Gaps = 9/226 (3%)

Query: 213 EEIYQYLREAEIRHRPKAHYMK-KQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNF 271
           + + Q L   E R+ P+A Y +  Q +I   MR +L  W++EV EE +   E   LA+N+
Sbjct: 25  QRVLQSLLRLEERYVPRASYFQCVQREIKPHMRKMLAYWMLEVCEEQRCEEEVFPLAMNY 84

Query: 272 LDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLL 331
           LDR+LSC+   + +LQL+G   MLLASK  E  P  +++    TD   + RQL   E L+
Sbjct: 85  LDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPRQLRDWEVLV 144

Query: 332 LKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAE--LSLLEAD-PFLKYLPSLIA 388
           L  L +DL     + FL   L R  +    + L K  A+  L+L   D  F  Y PS+IA
Sbjct: 145 LGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKKHAQTFLALCATDYTFAMYPPSMIA 204

Query: 389 -----AAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSELHKA 429
                AA   L   +++     E LA  TG  +  +  C  ++  A
Sbjct: 205 TGSIGAAVQGLGACSMSGDELTELLAGITGTEVDCLRACQEQIEAA 250


>gi|153791755 cyclin domain containing [Homo sapiens]
          Length = 350

 Score = 99.8 bits (247), Expect = 5e-21
 Identities = 62/201 (30%), Positives = 102/201 (50%), Gaps = 10/201 (4%)

Query: 204 DVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAE 263
           D+    +Y +  Y + +  E    P+   + +QP +T   R  L+ WL+ V  ++ L  E
Sbjct: 94  DLQTFRDYGQSCYAFRKAQESHFHPR-EALARQPQVTAESRCKLLSWLIPVHRQFGLSFE 152

Query: 264 TLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQ 323
           +L L VN LDRFL+   V     QL+G  ++L+A K  E++PP V + + +    ++++Q
Sbjct: 153 SLCLTVNTLDRFLTTTPVAADCFQLLGVTSLLIACKQVEVHPPRVKQLLALCCGAFSRQQ 212

Query: 324 LLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQ--------GVCVRTENLAKYVAELSLLE 375
           L  +E ++L  L F L  PT + FL  +   +           +  + LA+ VAELSL +
Sbjct: 213 LCNLECIVLHKLHFTLGAPTISFFLEHFTHARVEAGQAEASEALEAQALARGVAELSLAD 272

Query: 376 ADPFLKYLPSLIAAAAFCLAN 396
              F  Y PSL+A     LA+
Sbjct: 273 Y-AFTSYSPSLLAICCLALAD 292


>gi|16950655 cyclin D1 [Homo sapiens]
          Length = 295

 Score = 93.2 bits (230), Expect = 4e-19
 Identities = 59/192 (30%), Positives = 100/192 (52%), Gaps = 4/192 (2%)

Query: 213 EEIYQYLREAEIRHRPKAHYMK-KQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNF 271
           + + + + +AE    P   Y K  Q ++   MR I+  W++EV EE K   E   LA+N+
Sbjct: 25  DRVLRAMLKAEETCAPSVSYFKCVQKEVLPSMRKIVATWMLEVCEEQKCEEEVFPLAMNY 84

Query: 272 LDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLL 331
           LDRFLS   V + +LQL+G   M +ASK +E  P   ++    TD++    +LL+ME LL
Sbjct: 85  LDRFLSLEPVKKSRLQLLGATCMFVASKMKETIPLTAEKLCIYTDNSIRPEELLQMELLL 144

Query: 332 LKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAE--LSLLEAD-PFLKYLPSLIA 388
           +  L ++L   T + F+  +L +       + + +  A+  ++L   D  F+   PS++A
Sbjct: 145 VNKLKWNLAAMTPHDFIEHFLSKMPEAEENKQIIRKHAQTFVALCATDVKFISNPPSMVA 204

Query: 389 AAAFCLANYTVN 400
           A +   A   +N
Sbjct: 205 AGSVVAAVQGLN 216


>gi|242247025 cyclin N-terminal domain containing 2 isoform 2 [Homo
           sapiens]
          Length = 307

 Score = 91.3 bits (225), Expect = 2e-18
 Identities = 73/204 (35%), Positives = 104/204 (50%), Gaps = 14/204 (6%)

Query: 196 EDISSLGTDVINVTEYAEEIYQYL---REAEIRHRPKAHYMKKQPDITEGMRTILVDWLV 252
           E +S+LG       EYA +I+  +   R   +R  P+A        +T  MR ++VDWLV
Sbjct: 67  EALSALGLQ--GEREYAGDIFAEVMVCRVLPLRALPRA--------VTPEMRALVVDWLV 116

Query: 253 EVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFV 312
           +V E   L  +TLYLAV+ LD +LS   V   +LQL+G A + +A K EE   PE     
Sbjct: 117 QVHEYLGLAGDTLYLAVHLLDSYLSAGRVRLHRLQLLGVACLFVACKMEECVLPEPAFLC 176

Query: 313 YITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELS 372
            ++ D++++ +LL+ E  +L  L F L  P     L       G   +   LA Y  ELS
Sbjct: 177 LLSADSFSRAELLRAERRILSRLDFRLHHPGPLLCLGLLAALAGSSPQVMLLATYFLELS 236

Query: 373 LLEADPFLKYLPSLIAAAAFCLAN 396
           LLEA+    + P   AAAA  LA+
Sbjct: 237 LLEAEA-AGWEPGRRAAAALSLAH 259


>gi|4502617 cyclin D2 [Homo sapiens]
          Length = 289

 Score = 88.2 bits (217), Expect = 1e-17
 Identities = 63/189 (33%), Positives = 98/189 (51%), Gaps = 8/189 (4%)

Query: 213 EEIYQYLREAEIRHRPKAHYMK-KQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNF 271
           + + Q L   E R+ P+  Y K  Q DI   MR ++  W++EV EE K   E   LA+N+
Sbjct: 24  DRVLQNLLTIEERYLPQCSYFKCVQKDIQPYMRRMVATWMLEVCEEQKCEEEVFPLAMNY 83

Query: 272 LDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLL 331
           LDRFL+ +   +  LQL+G   M LASK +E  P   ++    TD++   ++LL+ E ++
Sbjct: 84  LDRFLAGVPTPKSHLQLLGAVCMFLASKLKETSPLTAEKLCIYTDNSIKPQELLEWELVV 143

Query: 332 LKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAE--LSLLEAD-PFLKYLPSLIA 388
           L  L ++L   T + F+   LR+        +L +  A+  ++L   D  F  Y PS+IA
Sbjct: 144 LGKLKWNLAAVTPHDFIEHILRKLPQQREKLSLIRKHAQTFIALCATDFKFAMYPPSMIA 203

Query: 389 ----AAAFC 393
                AA C
Sbjct: 204 TGSVGAAIC 212


>gi|197276674 cyclin J isoform 1 [Homo sapiens]
          Length = 383

 Score = 77.8 bits (190), Expect = 2e-14
 Identities = 72/243 (29%), Positives = 111/243 (45%), Gaps = 34/243 (13%)

Query: 210 EYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAV 269
           + A +I+Q LR  E++      Y  + P ++  +R    D +  V   + L     +LAV
Sbjct: 11  QLAADIHQALRYKELK---LPSYKGQSPQLS--LRRYFADLIAIVSNRFTLCPSARHLAV 65

Query: 270 NFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYP--PEVDEFVYITDDT-----YTKR 322
             LD F+    +   +L LV  + +LLASK+EE     P++++   +   T      TK+
Sbjct: 66  YLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQ 125

Query: 323 QLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRR-----------QGVCVRTENL-----AK 366
            LL ME LLL+   ++L +PT   F+  YL               +C+    L     A 
Sbjct: 126 NLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMAKYAD 185

Query: 367 YVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHF---WPETLAAFTGYSLSEIVPCL 423
           Y  E+SL +   FL Y PSL+AAA  C+A+  +       WP  L   T YS   +V C+
Sbjct: 186 YFLEVSLQDY-AFLNYAPSLVAAA--CVASSRIILRLSPTWPTRLHRLTAYSWDFLVQCI 242

Query: 424 SEL 426
             L
Sbjct: 243 ERL 245


>gi|209862835 cyclin D3 isoform 1 [Homo sapiens]
          Length = 211

 Score = 72.8 bits (177), Expect = 6e-13
 Identities = 56/169 (33%), Positives = 82/169 (48%), Gaps = 8/169 (4%)

Query: 269 VNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKME 328
           +N+LDR+LSC+   + +LQL+G   MLLASK  E  P  +++    TD   + RQL   E
Sbjct: 1   MNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPRQLRDWE 60

Query: 329 HLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAE--LSLLEAD-PFLKYLPS 385
            L+L  L +DL     + FL   L R  +    + L K  A+  L+L   D  F  Y PS
Sbjct: 61  VLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKKHAQTFLALCATDYTFAMYPPS 120

Query: 386 LIA-----AAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSELHKA 429
           +IA     AA   L   +++     E LA  TG  +  +  C  ++  A
Sbjct: 121 MIATGSIGAAVQGLGACSMSGDELTELLAGITGTEVDCLRACQEQIEAA 169


>gi|40254889 cyclin J isoform 2 [Homo sapiens]
          Length = 372

 Score = 65.9 bits (159), Expect = 8e-11
 Identities = 70/240 (29%), Positives = 107/240 (44%), Gaps = 39/240 (16%)

Query: 210 EYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAV 269
           + A +I+Q LR  E++      Y  + P ++  +R    D +  V   + L     +LAV
Sbjct: 11  QLAADIHQALRYKELK---LPSYKGQSPQLS--LRRYFADLIAIVSNRFTLCPSARHLAV 65

Query: 270 NFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYP--PEVDEFVYITDDT-----YTKR 322
             LD F+    +   +L LV  + +LLASK+EE     P++++   +   T      TK+
Sbjct: 66  YLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQ 125

Query: 323 QLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRR-----------QGVCVRTENL--AKYVA 369
            LL ME LLL+   ++L +PT   F+  YL               +C+    L  AKY  
Sbjct: 126 NLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMAKY-- 183

Query: 370 ELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHF---WPETLAAFTGYSLSEIVPCLSEL 426
                 AD FL+   SL  AAA C+A+  +       WP  L   T YS   +V C+  L
Sbjct: 184 ------ADYFLEV--SLQVAAA-CVASSRIILRLSPTWPTRLHRLTAYSWDFLVQCIERL 234


>gi|197276676 cyclin J isoform 3 [Homo sapiens]
          Length = 371

 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 63/231 (27%), Positives = 101/231 (43%), Gaps = 22/231 (9%)

Query: 210 EYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAV 269
           + A +I+Q LR  E++      Y  + P ++  +R    D +  V   + L     +LAV
Sbjct: 11  QLAADIHQALRYKELK---LPSYKGQSPQLS--LRRYFADLIAIVSNRFTLCPSARHLAV 65

Query: 270 NFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYP--PEVDEFVYITDDT-----YTKR 322
             LD F+    +   +L LV  + +LLASK+EE     P++++   +   T      TK+
Sbjct: 66  YLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQ 125

Query: 323 QLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENL----AKYVAELSLLEADP 378
            LL ME LLL+   ++L +PT   F+  YL      V   +L         E + L    
Sbjct: 126 NLLHMELLLLETFQWNLCLPTAAHFIEYYLSE---AVHETDLHDGWPMICLEKTKLYMAK 182

Query: 379 FLKYLPSLIAAAAFCLANYTVNKHF---WPETLAAFTGYSLSEIVPCLSEL 426
           +  Y   +   AA C+A+  +       WP  L   T YS   +V C+  L
Sbjct: 183 YADYFLEVSLQAAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQCIERL 233


>gi|40805832 cyclin G1 [Homo sapiens]
          Length = 295

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 58/208 (27%), Positives = 96/208 (46%), Gaps = 17/208 (8%)

Query: 204 DVINVTEYAEEIYQY--LREAEIRHRPKA---HYMKKQPD----ITEGMRTILVDWLVEV 254
           +V+  T+  + ++Q   L E E R +PK      ++   D    +T  +R   V  L+ +
Sbjct: 3   EVLTTTDSQKLLHQLNALLEQESRCQPKVCGLRLIESAHDNGLRMTARLRDFEVKDLLSL 62

Query: 255 GEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASK--YEEIYPPEVDEFV 312
            + +    ET  LAVN LDRFLS M V    L  VG +   LA K   EE   P   + +
Sbjct: 63  TQFFGFDTETFSLAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATDLI 122

Query: 313 YITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQY--LRRQGVCVRTENLAKYVAE 370
            I+   +T   L++ME ++L+ + + +   T  QFL  Y  L ++ + +   N   +   
Sbjct: 123 RISQYRFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSLLQENLPLERRNSINFERL 182

Query: 371 LSLLEADP----FLKYLPSLIAAAAFCL 394
            + L+A      F K  PS++A +   L
Sbjct: 183 EAQLKACHCRIIFSKAKPSVLALSIIAL 210


>gi|4757934 cyclin G1 [Homo sapiens]
          Length = 295

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 58/208 (27%), Positives = 96/208 (46%), Gaps = 17/208 (8%)

Query: 204 DVINVTEYAEEIYQY--LREAEIRHRPKA---HYMKKQPD----ITEGMRTILVDWLVEV 254
           +V+  T+  + ++Q   L E E R +PK      ++   D    +T  +R   V  L+ +
Sbjct: 3   EVLTTTDSQKLLHQLNALLEQESRCQPKVCGLRLIESAHDNGLRMTARLRDFEVKDLLSL 62

Query: 255 GEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASK--YEEIYPPEVDEFV 312
            + +    ET  LAVN LDRFLS M V    L  VG +   LA K   EE   P   + +
Sbjct: 63  TQFFGFDTETFSLAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATDLI 122

Query: 313 YITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQY--LRRQGVCVRTENLAKYVAE 370
            I+   +T   L++ME ++L+ + + +   T  QFL  Y  L ++ + +   N   +   
Sbjct: 123 RISQYRFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSLLQENLPLERRNSINFERL 182

Query: 371 LSLLEADP----FLKYLPSLIAAAAFCL 394
            + L+A      F K  PS++A +   L
Sbjct: 183 EAQLKACHCRIIFSKAKPSVLALSIIAL 210


>gi|4757936 cyclin G2 [Homo sapiens]
          Length = 344

 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 50/168 (29%), Positives = 75/168 (44%), Gaps = 16/168 (9%)

Query: 242 GMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKY- 300
           G+R   V+ L  +   +    ET  LAVN LDRFL+ M V    L  +G  + LLA++  
Sbjct: 54  GLRNAKVEDLRSLANFFGSCTETFVLAVNILDRFLALMKVKPKHLSCIGVCSFLLAARIV 113

Query: 301 -EEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCV 359
            E+   P   + + I+    T   + +ME ++ + L ++L   T   FL  Y     +C 
Sbjct: 114 EEDCNIPSTHDVIRISQCKCTASDIKRMEKIISEKLHYELEATTALNFLHLY-HTIILCH 172

Query: 360 RTENLAKYVAELSLLEAD--------PFLKYLPSLIAAAAFCLANYTV 399
            +E   K +  L  LEA          F K  PS++   A CL N  V
Sbjct: 173 TSER--KEILSLDKLEAQLKACNCRLIFSKAKPSVL---ALCLLNLEV 215


>gi|5802992 cyclin I [Homo sapiens]
          Length = 377

 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 33/132 (25%), Positives = 62/132 (46%), Gaps = 5/132 (3%)

Query: 220 REAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCM 279
           REA++  +     M    +++   R  ++ WL ++  ++ L  ET  LA + LDRFL+ +
Sbjct: 22  REAQM-WKVNVRKMPSNQNVSPSQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATV 80

Query: 280 SVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTY---TKRQLLKMEHLLLKVLA 336
                 L  +  +   LA+K  E     +     +  D++   +  ++L+ME ++L  L 
Sbjct: 81  KAHPKYLSCIAISCFFLAAKTVE-EDERIPVLKVLARDSFCGCSSSEILRMERIILDKLN 139

Query: 337 FDLTVPTTNQFL 348
           +DL   T   FL
Sbjct: 140 WDLHTATPLDFL 151


>gi|94680985 cyclin J-like [Homo sapiens]
          Length = 435

 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 37/133 (27%), Positives = 59/133 (44%), Gaps = 23/133 (17%)

Query: 318 TYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYL-------------------RRQGVC 358
           T TK++LL  E LLL+  +++L +PT   FL  YL                   R+   C
Sbjct: 169 TLTKKELLSTELLLLEAFSWNLCLPTPAHFLDYYLLASVSQKDHHCHTWPTTCPRKTKEC 228

Query: 359 VRTENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTVN-KHFWPETLAAFTGYSLS 417
           ++    A Y  E++ L+   F K+ PS++AAA    +   +    +W   L   + YSL 
Sbjct: 229 LK--EYAHYFLEVT-LQDHIFYKFQPSVVAAACVGASRICLQLSPYWTRDLQRISSYSLE 285

Query: 418 EIVPCLSELHKAY 430
            +  C+  L   Y
Sbjct: 286 HLSTCIEILLVVY 298


>gi|89886237 cyclin I family, member 2 [Homo sapiens]
          Length = 369

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 32/117 (27%), Positives = 54/117 (46%), Gaps = 3/117 (2%)

Query: 234 KKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAA 293
           K Q +I +    +++ WL+ +   +     T  LA+    R L  + V    L      +
Sbjct: 141 KPQDEICDAFEEVVL-WLLRLQNTFYFSQSTFNLALTIFGRLLISVKVKEKYLHCATITS 199

Query: 294 MLLASKY--EEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFL 348
           + LA+K   EE + P+V +F       Y+  +LL+ME  +L  L +DL + T   FL
Sbjct: 200 LRLAAKVNEEEEFIPQVKDFTKHYGSDYSPNELLRMELAILDRLHWDLYIGTPLDFL 256


>gi|150417989 cyclin K isoform 1 [Homo sapiens]
          Length = 580

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 31/117 (26%), Positives = 51/117 (43%), Gaps = 14/117 (11%)

Query: 250 WLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVD 309
           ++ +VG    L  +TL   + +  RF    S  +    + G   + LA K EE      D
Sbjct: 56  FIFDVGTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGACCLFLAGKVEETPKKCKD 115

Query: 310 ------------EFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRR 354
                       +F    DD   K +++ +E +LL+ + FDL V    QFLL+Y ++
Sbjct: 116 IIKTARSLLNDVQFGQFGDDP--KEEVMVLERILLQTIKFDLQVEHPYQFLLKYAKQ 170


>gi|38176158 cyclin K isoform 2 [Homo sapiens]
          Length = 354

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 31/117 (26%), Positives = 51/117 (43%), Gaps = 14/117 (11%)

Query: 250 WLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVD 309
           ++ +VG    L  +TL   + +  RF    S  +    + G   + LA K EE      D
Sbjct: 56  FIFDVGTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGACCLFLAGKVEETPKKCKD 115

Query: 310 ------------EFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRR 354
                       +F    DD   K +++ +E +LL+ + FDL V    QFLL+Y ++
Sbjct: 116 IIKTARSLLNDVQFGQFGDDP--KEEVMVLERILLQTIKFDLQVEHPYQFLLKYAKQ 170


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.137    0.411 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,699,862
Number of Sequences: 37866
Number of extensions: 861973
Number of successful extensions: 1901
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 1837
Number of HSP's gapped (non-prelim): 48
length of query: 465
length of database: 18,247,518
effective HSP length: 106
effective length of query: 359
effective length of database: 14,233,722
effective search space: 5109906198
effective search space used: 5109906198
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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