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Search of human proteins with 4502611
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4502611 cyclin A1 isoform a [Homo sapiens]
(465 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4502611 cyclin A1 isoform a [Homo sapiens] 942 0.0
gi|161377468 cyclin A1 isoform b [Homo sapiens] 935 0.0
gi|161377472 cyclin A1 isoform c [Homo sapiens] 847 0.0
gi|161377470 cyclin A1 isoform c [Homo sapiens] 847 0.0
gi|4502613 cyclin A [Homo sapiens] 348 5e-96
gi|4757930 cyclin B2 [Homo sapiens] 184 1e-46
gi|14327896 cyclin B1 [Homo sapiens] 172 4e-43
gi|90669307 cyclin B3 isoform 3 [Homo sapiens] 160 2e-39
gi|16306525 cyclin B3 isoform 1 [Homo sapiens] 119 4e-27
gi|118572588 cyclin F [Homo sapiens] 112 5e-25
gi|17318559 cyclin E1 isoform 1 [Homo sapiens] 105 7e-23
gi|17318561 cyclin E1 isoform 2 [Homo sapiens] 105 7e-23
gi|17318565 cyclin E2 [Homo sapiens] 103 4e-22
gi|4502619 cyclin D3 isoform 2 [Homo sapiens] 101 1e-21
gi|153791755 cyclin domain containing [Homo sapiens] 100 5e-21
gi|16950655 cyclin D1 [Homo sapiens] 93 4e-19
gi|242247025 cyclin N-terminal domain containing 2 isoform 2 [Ho... 91 2e-18
gi|4502617 cyclin D2 [Homo sapiens] 88 1e-17
gi|197276674 cyclin J isoform 1 [Homo sapiens] 78 2e-14
gi|209862835 cyclin D3 isoform 1 [Homo sapiens] 73 6e-13
gi|40254889 cyclin J isoform 2 [Homo sapiens] 66 8e-11
gi|197276676 cyclin J isoform 3 [Homo sapiens] 65 1e-10
gi|40805832 cyclin G1 [Homo sapiens] 55 2e-07
gi|4757934 cyclin G1 [Homo sapiens] 55 2e-07
gi|4757936 cyclin G2 [Homo sapiens] 54 4e-07
gi|5802992 cyclin I [Homo sapiens] 46 6e-05
gi|94680985 cyclin J-like [Homo sapiens] 46 8e-05
gi|89886237 cyclin I family, member 2 [Homo sapiens] 45 1e-04
gi|150417989 cyclin K isoform 1 [Homo sapiens] 40 0.003
gi|38176158 cyclin K isoform 2 [Homo sapiens] 40 0.003
>gi|4502611 cyclin A1 isoform a [Homo sapiens]
Length = 465
Score = 942 bits (2434), Expect = 0.0
Identities = 465/465 (100%), Positives = 465/465 (100%)
Query: 1 METGFPAIMYPGSFIGGWGEEYLSWEGPGLPDFVFQQQPVESEAMHCSNPKSGVVLATVA 60
METGFPAIMYPGSFIGGWGEEYLSWEGPGLPDFVFQQQPVESEAMHCSNPKSGVVLATVA
Sbjct: 1 METGFPAIMYPGSFIGGWGEEYLSWEGPGLPDFVFQQQPVESEAMHCSNPKSGVVLATVA 60
Query: 61 RGPDACQILTRAPLGQDPPQRTVLGLLTANGQYRRTCGQGITRIRCYSGSENAFPPAGKK 120
RGPDACQILTRAPLGQDPPQRTVLGLLTANGQYRRTCGQGITRIRCYSGSENAFPPAGKK
Sbjct: 61 RGPDACQILTRAPLGQDPPQRTVLGLLTANGQYRRTCGQGITRIRCYSGSENAFPPAGKK 120
Query: 121 ALPDCGVQEPPKQGFDIYMDELEQGDRDSCSVREGMAFEDVYEVDTGTLKSDLHFLLDFN 180
ALPDCGVQEPPKQGFDIYMDELEQGDRDSCSVREGMAFEDVYEVDTGTLKSDLHFLLDFN
Sbjct: 121 ALPDCGVQEPPKQGFDIYMDELEQGDRDSCSVREGMAFEDVYEVDTGTLKSDLHFLLDFN 180
Query: 181 TVSPMLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDIT 240
TVSPMLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDIT
Sbjct: 181 TVSPMLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDIT 240
Query: 241 EGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKY 300
EGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKY
Sbjct: 241 EGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKY 300
Query: 301 EEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVR 360
EEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVR
Sbjct: 301 EEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVR 360
Query: 361 TENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIV 420
TENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIV
Sbjct: 361 TENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIV 420
Query: 421 PCLSELHKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLLQ 465
PCLSELHKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLLQ
Sbjct: 421 PCLSELHKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLLQ 465
>gi|161377468 cyclin A1 isoform b [Homo sapiens]
Length = 464
Score = 935 bits (2417), Expect = 0.0
Identities = 464/465 (99%), Positives = 464/465 (99%), Gaps = 1/465 (0%)
Query: 1 METGFPAIMYPGSFIGGWGEEYLSWEGPGLPDFVFQQQPVESEAMHCSNPKSGVVLATVA 60
METGFPAIMYPGSFIGGWGEEYLSWEGPGLPDFVFQQ PVESEAMHCSNPKSGVVLATVA
Sbjct: 1 METGFPAIMYPGSFIGGWGEEYLSWEGPGLPDFVFQQ-PVESEAMHCSNPKSGVVLATVA 59
Query: 61 RGPDACQILTRAPLGQDPPQRTVLGLLTANGQYRRTCGQGITRIRCYSGSENAFPPAGKK 120
RGPDACQILTRAPLGQDPPQRTVLGLLTANGQYRRTCGQGITRIRCYSGSENAFPPAGKK
Sbjct: 60 RGPDACQILTRAPLGQDPPQRTVLGLLTANGQYRRTCGQGITRIRCYSGSENAFPPAGKK 119
Query: 121 ALPDCGVQEPPKQGFDIYMDELEQGDRDSCSVREGMAFEDVYEVDTGTLKSDLHFLLDFN 180
ALPDCGVQEPPKQGFDIYMDELEQGDRDSCSVREGMAFEDVYEVDTGTLKSDLHFLLDFN
Sbjct: 120 ALPDCGVQEPPKQGFDIYMDELEQGDRDSCSVREGMAFEDVYEVDTGTLKSDLHFLLDFN 179
Query: 181 TVSPMLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDIT 240
TVSPMLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDIT
Sbjct: 180 TVSPMLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDIT 239
Query: 241 EGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKY 300
EGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKY
Sbjct: 240 EGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKY 299
Query: 301 EEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVR 360
EEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVR
Sbjct: 300 EEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVR 359
Query: 361 TENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIV 420
TENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIV
Sbjct: 360 TENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIV 419
Query: 421 PCLSELHKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLLQ 465
PCLSELHKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLLQ
Sbjct: 420 PCLSELHKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLLQ 464
>gi|161377472 cyclin A1 isoform c [Homo sapiens]
Length = 421
Score = 847 bits (2187), Expect = 0.0
Identities = 421/421 (100%), Positives = 421/421 (100%)
Query: 45 MHCSNPKSGVVLATVARGPDACQILTRAPLGQDPPQRTVLGLLTANGQYRRTCGQGITRI 104
MHCSNPKSGVVLATVARGPDACQILTRAPLGQDPPQRTVLGLLTANGQYRRTCGQGITRI
Sbjct: 1 MHCSNPKSGVVLATVARGPDACQILTRAPLGQDPPQRTVLGLLTANGQYRRTCGQGITRI 60
Query: 105 RCYSGSENAFPPAGKKALPDCGVQEPPKQGFDIYMDELEQGDRDSCSVREGMAFEDVYEV 164
RCYSGSENAFPPAGKKALPDCGVQEPPKQGFDIYMDELEQGDRDSCSVREGMAFEDVYEV
Sbjct: 61 RCYSGSENAFPPAGKKALPDCGVQEPPKQGFDIYMDELEQGDRDSCSVREGMAFEDVYEV 120
Query: 165 DTGTLKSDLHFLLDFNTVSPMLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEI 224
DTGTLKSDLHFLLDFNTVSPMLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEI
Sbjct: 121 DTGTLKSDLHFLLDFNTVSPMLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEI 180
Query: 225 RHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRG 284
RHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRG
Sbjct: 181 RHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRG 240
Query: 285 KLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTT 344
KLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTT
Sbjct: 241 KLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTT 300
Query: 345 NQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFW 404
NQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFW
Sbjct: 301 NQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFW 360
Query: 405 PETLAAFTGYSLSEIVPCLSELHKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLL 464
PETLAAFTGYSLSEIVPCLSELHKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLL
Sbjct: 361 PETLAAFTGYSLSEIVPCLSELHKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLL 420
Query: 465 Q 465
Q
Sbjct: 421 Q 421
>gi|161377470 cyclin A1 isoform c [Homo sapiens]
Length = 421
Score = 847 bits (2187), Expect = 0.0
Identities = 421/421 (100%), Positives = 421/421 (100%)
Query: 45 MHCSNPKSGVVLATVARGPDACQILTRAPLGQDPPQRTVLGLLTANGQYRRTCGQGITRI 104
MHCSNPKSGVVLATVARGPDACQILTRAPLGQDPPQRTVLGLLTANGQYRRTCGQGITRI
Sbjct: 1 MHCSNPKSGVVLATVARGPDACQILTRAPLGQDPPQRTVLGLLTANGQYRRTCGQGITRI 60
Query: 105 RCYSGSENAFPPAGKKALPDCGVQEPPKQGFDIYMDELEQGDRDSCSVREGMAFEDVYEV 164
RCYSGSENAFPPAGKKALPDCGVQEPPKQGFDIYMDELEQGDRDSCSVREGMAFEDVYEV
Sbjct: 61 RCYSGSENAFPPAGKKALPDCGVQEPPKQGFDIYMDELEQGDRDSCSVREGMAFEDVYEV 120
Query: 165 DTGTLKSDLHFLLDFNTVSPMLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEI 224
DTGTLKSDLHFLLDFNTVSPMLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEI
Sbjct: 121 DTGTLKSDLHFLLDFNTVSPMLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEI 180
Query: 225 RHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRG 284
RHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRG
Sbjct: 181 RHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRG 240
Query: 285 KLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTT 344
KLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTT
Sbjct: 241 KLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTT 300
Query: 345 NQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFW 404
NQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFW
Sbjct: 301 NQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFW 360
Query: 405 PETLAAFTGYSLSEIVPCLSELHKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLL 464
PETLAAFTGYSLSEIVPCLSELHKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLL
Sbjct: 361 PETLAAFTGYSLSEIVPCLSELHKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLL 420
Query: 465 Q 465
Q
Sbjct: 421 Q 421
>gi|4502613 cyclin A [Homo sapiens]
Length = 432
Score = 348 bits (894), Expect = 5e-96
Identities = 190/338 (56%), Positives = 238/338 (70%), Gaps = 12/338 (3%)
Query: 135 FDIYMDELEQGDRDSCSVREGMAFEDVYEVDT-----GTLKS--DLHFLLDFNTVSPMLV 187
F I++DE E+ + + + + ED ++ G K L + +D + SP +
Sbjct: 99 FTIHVDEAEKEAQKKPAESQKIEREDALAFNSAISLPGPRKPLVPLDYPMDGSFESPHTM 158
Query: 188 DSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTIL 247
D S++ + E S+ V +Y E+I+ YLRE E++ +PK YMKKQPDIT MR IL
Sbjct: 159 DMSIVLEDEKPVSVN----EVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAIL 214
Query: 248 VDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPE 307
VDWLVEVGEEYKL+ ETL+LAVN++DRFLS MSVLRGKLQLVGTAAMLLASK+EEIYPPE
Sbjct: 215 VDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPE 274
Query: 308 VDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQY-LRRQGVCVRTENLAK 366
V EFVYITDDTYTK+Q+L+MEHL+LKVL FDL PT NQFL QY L +Q + E+LA
Sbjct: 275 VAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAM 334
Query: 367 YVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSEL 426
++ ELSL++ADP+LKYLPS+IA AAF LA YTV WPE+L TGY+L + PCL +L
Sbjct: 335 FLGELSLIDADPYLKYLPSVIAGAAFHLALYTVTGQSWPESLIRKTGYTLESLKPCLMDL 394
Query: 427 HKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLL 464
H+ YL P QQ+IREKYK SKY VSL+ PP L L
Sbjct: 395 HQTYLKAPQHAQQSIREKYKNSKYHGVSLLNPPETLNL 432
>gi|4757930 cyclin B2 [Homo sapiens]
Length = 398
Score = 184 bits (468), Expect = 1e-46
Identities = 107/270 (39%), Positives = 164/270 (60%), Gaps = 5/270 (1%)
Query: 190 SLLSQSEDISSLGTDVINV-TEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILV 248
+LL + EDI + + + ++Y ++IYQYLR+ E+ H++ + DI MR ILV
Sbjct: 112 ALLCKIEDIDNEDWENPQLCSDYVKDIYQYLRQLEVLQSINPHFLDGR-DINGRMRAILV 170
Query: 249 DWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEV 308
DWLV+V +++L ETLY+ V +DRFL V R KLQLVG A+LLASKYEE++ P +
Sbjct: 171 DWLVQVHSKFRLLQETLYMCVGIMDRFLQVQPVSRKKLQLVGITALLLASKYEEMFSPNI 230
Query: 309 DEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYV 368
++FVYITD+ YT Q+ +ME L+LK L F+L P FL + + V V LAKY+
Sbjct: 231 EDFVYITDNAYTSSQIREMETLILKELKFELGRPLPLHFLRRASKAGEVDVEQHTLAKYL 290
Query: 369 AELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSELHK 428
EL+L++ D + Y PS +AAAA CL+ + + W +TGY+ +E++ + + K
Sbjct: 291 MELTLIDYD-MVHYHPSKVAAAASCLSQKVLGQGKWNLKQQYYTGYTENEVLEVMQHMAK 349
Query: 429 AYLDIPHRPQQ--AIREKYKASKYLCVSLM 456
+ + + AI+ KY +SK L +S++
Sbjct: 350 NVVKVNENLTKFIAIKNKYASSKLLKISMI 379
>gi|14327896 cyclin B1 [Homo sapiens]
Length = 433
Score = 172 bits (437), Expect = 4e-43
Identities = 96/257 (37%), Positives = 149/257 (57%), Gaps = 4/257 (1%)
Query: 202 GTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLR 261
G D +EY ++IY YLR+ E + Y+ + ++T MR IL+DWLV+V +++L
Sbjct: 161 GADPNLCSEYVKDIYAYLRQLEEEQAVRPKYLLGR-EVTGNMRAILIDWLVQVQMKFRLL 219
Query: 262 AETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTK 321
ET+Y+ V+ +DRF+ V + LQLVG AM +ASKYEE+YPPE+ +F ++TD+TYTK
Sbjct: 220 QETMYMTVSIIDRFMQNNCVPKKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVTDNTYTK 279
Query: 322 RQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLK 381
Q+ +ME +L+ L F L P FL + + V V LAKY+ EL++L+ D +
Sbjct: 280 HQIRQMEMKILRALNFGLGRPLPLHFLRRASKIGEVDVEQHTLAKYLMELTMLDYD-MVH 338
Query: 382 YLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSELHKAYLDIPH--RPQQ 439
+ PS IAA AFCLA ++ W TL + Y+ ++P + L K + +
Sbjct: 339 FPPSQIAAGAFCLALKILDNGEWTPTLQHYLSYTEESLLPVMQHLAKNVVMVNQGLTKHM 398
Query: 440 AIREKYKASKYLCVSLM 456
++ KY SK+ +S +
Sbjct: 399 TVKNKYATSKHAKISTL 415
>gi|90669307 cyclin B3 isoform 3 [Homo sapiens]
Length = 1395
Score = 160 bits (406), Expect = 2e-39
Identities = 94/254 (37%), Positives = 146/254 (57%), Gaps = 2/254 (0%)
Query: 192 LSQSEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWL 251
++ EDI +D YA+EI+ Y++E E + YM +Q +IT MR ILVDWL
Sbjct: 1110 ITPREDIDEDSSDPSFNPMYAKEIFSYMKEREEQFI-LTDYMNRQIEITSDMRAILVDWL 1168
Query: 252 VEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEF 311
VEV +++ ETLYLAV +D +L + KLQL+G A ++A+K+EE P VD+F
Sbjct: 1169 VEVQVSFEMTHETLYLAVKLVDLYLMKAVCKKDKLQLLGATAFMIAAKFEEHNSPRVDDF 1228
Query: 312 VYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAEL 371
VYI DD Y + ++L ME +L VL D+ +P FL +Y R ++T L++Y+ E+
Sbjct: 1229 VYICDDNYQRSEVLSMEINILNVLKCDINIPIAYHFLRRYARCIHTNMKTLTLSRYICEM 1288
Query: 372 SLLEADPFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSELHKAYL 431
+L E +++ S +AAA+ LA Y +W L ++GYS+SE+ P + +L+K
Sbjct: 1289 TLQEYH-YVQEKASKLAAASLLLALYMKKLGYWVPFLEHYSGYSISELHPLVRQLNKLLT 1347
Query: 432 DIPHRPQQAIREKY 445
+ +A+ KY
Sbjct: 1348 FSSYDSLKAVYYKY 1361
>gi|16306525 cyclin B3 isoform 1 [Homo sapiens]
Length = 291
Score = 119 bits (299), Expect = 4e-27
Identities = 67/188 (35%), Positives = 109/188 (57%), Gaps = 1/188 (0%)
Query: 258 YKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDD 317
+++ ETLYLAV +D +L + KLQL+G A ++A+K+EE P VD+FVYI DD
Sbjct: 71 FEMTHETLYLAVKLVDLYLMKAVCKKDKLQLLGATAFMIAAKFEEHNSPRVDDFVYICDD 130
Query: 318 TYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELSLLEAD 377
Y + ++L ME +L VL D+ +P FL +Y R ++T L++Y+ E++L E
Sbjct: 131 NYQRSEVLSMEINILNVLKCDINIPIAYHFLRRYARCIHTNMKTLTLSRYICEMTLQEYH 190
Query: 378 PFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSELHKAYLDIPHRP 437
+++ S +AAA+ LA Y +W L ++GYS+SE+ P + +L+K +
Sbjct: 191 -YVQEKASKLAAASLLLALYMKKLGYWVPFLEHYSGYSISELHPLVRQLNKLLTFSSYDS 249
Query: 438 QQAIREKY 445
+A+ KY
Sbjct: 250 LKAVYYKY 257
>gi|118572588 cyclin F [Homo sapiens]
Length = 786
Score = 112 bits (281), Expect = 5e-25
Identities = 91/333 (27%), Positives = 153/333 (45%), Gaps = 20/333 (6%)
Query: 128 QEPPKQGFDIYMDELEQGDRDSCSVREGMAFEDVYEVDTGTLKSDLHF---LLDFNTVSP 184
+E +Q D++ + QG C + +E D LH L D+
Sbjct: 200 EEKQQQAHDLFEEAAHQG----CLTSSYLLWESDRRTDVSDPGRCLHSFRKLRDYAAKGC 255
Query: 185 MLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMR 244
SL + + LG +V +E +++Q + K Q + + MR
Sbjct: 256 WEAQLSLAKACANANQLGLEVRASSEIVCQLFQASQAVS-----KQQVFSVQKGLNDTMR 310
Query: 245 TILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIY 304
IL+DWLVEV + L+L V +DR+L V R +LQL+G A M++ +++
Sbjct: 311 YILIDWLVEVATMKDFTSLCLHLTVECVDRYLRRRLVPRYRLQLLGIACMVICTRFISKE 370
Query: 305 PPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENL 364
+ E V++TD+TY L++M ++ L + VPT + L V +RT++L
Sbjct: 371 ILTIREAVWLTDNTYKYEDLVRMMGEIVSALEGKIRVPTVVDYKEVLLTLVPVELRTQHL 430
Query: 365 AKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNK-HFWPETLAAFTGYSLSEIVPCL 423
++ ELSLL Y P+ +AAAA LA T + W L TG+S +++PC+
Sbjct: 431 CSFLCELSLLHTS-LSAYAPARLAAAALLLARLTHGQTQPWTTQLWDLTGFSYEDLIPCV 489
Query: 424 SELHKA--YLDIPHRPQQ----AIREKYKASKY 450
LHK + D P +Q A++++++ +Y
Sbjct: 490 LSLHKKCFHDDAPKDYRQVSLTAVKQRFEDKRY 522
>gi|17318559 cyclin E1 isoform 1 [Homo sapiens]
Length = 410
Score = 105 bits (263), Expect = 7e-23
Identities = 52/142 (36%), Positives = 92/142 (64%), Gaps = 1/142 (0%)
Query: 213 EEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFL 272
EE+++ + E + H++++ P + MR IL+DWL+EV E YKL ET YLA +F
Sbjct: 114 EEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFF 173
Query: 273 DRFLSCM-SVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLL 331
DR+++ +V++ LQL+G +++ +A+K EEIYPP++ +F Y+TD + ++L ME ++
Sbjct: 174 DRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMI 233
Query: 332 LKVLAFDLTVPTTNQFLLQYLR 353
+K L + L+ T +L Y++
Sbjct: 234 MKALKWRLSPLTIVSWLNVYMQ 255
>gi|17318561 cyclin E1 isoform 2 [Homo sapiens]
Length = 395
Score = 105 bits (263), Expect = 7e-23
Identities = 52/142 (36%), Positives = 92/142 (64%), Gaps = 1/142 (0%)
Query: 213 EEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFL 272
EE+++ + E + H++++ P + MR IL+DWL+EV E YKL ET YLA +F
Sbjct: 99 EEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFF 158
Query: 273 DRFLSCM-SVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLL 331
DR+++ +V++ LQL+G +++ +A+K EEIYPP++ +F Y+TD + ++L ME ++
Sbjct: 159 DRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMI 218
Query: 332 LKVLAFDLTVPTTNQFLLQYLR 353
+K L + L+ T +L Y++
Sbjct: 219 MKALKWRLSPLTIVSWLNVYMQ 240
>gi|17318565 cyclin E2 [Homo sapiens]
Length = 404
Score = 103 bits (256), Expect = 4e-22
Identities = 54/143 (37%), Positives = 88/143 (61%), Gaps = 1/143 (0%)
Query: 212 AEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNF 271
++E++ + + E R+ H+ D+ MR+IL+DWL+EV E Y L ET YLA +F
Sbjct: 110 SKEVWLNMLKKESRYVHDKHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDF 169
Query: 272 LDRF-LSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHL 330
DRF L+ + + LQL+G ++ +ASK EEIY P++ EF Y+TD ++ +L+ME +
Sbjct: 170 FDRFMLTQKDINKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELI 229
Query: 331 LLKVLAFDLTVPTTNQFLLQYLR 353
+LK L ++L T +L +L+
Sbjct: 230 ILKALKWELCPVTIISWLNLFLQ 252
>gi|4502619 cyclin D3 isoform 2 [Homo sapiens]
Length = 292
Score = 101 bits (252), Expect = 1e-21
Identities = 76/226 (33%), Positives = 112/226 (49%), Gaps = 9/226 (3%)
Query: 213 EEIYQYLREAEIRHRPKAHYMK-KQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNF 271
+ + Q L E R+ P+A Y + Q +I MR +L W++EV EE + E LA+N+
Sbjct: 25 QRVLQSLLRLEERYVPRASYFQCVQREIKPHMRKMLAYWMLEVCEEQRCEEEVFPLAMNY 84
Query: 272 LDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLL 331
LDR+LSC+ + +LQL+G MLLASK E P +++ TD + RQL E L+
Sbjct: 85 LDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPRQLRDWEVLV 144
Query: 332 LKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAE--LSLLEAD-PFLKYLPSLIA 388
L L +DL + FL L R + + L K A+ L+L D F Y PS+IA
Sbjct: 145 LGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKKHAQTFLALCATDYTFAMYPPSMIA 204
Query: 389 -----AAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSELHKA 429
AA L +++ E LA TG + + C ++ A
Sbjct: 205 TGSIGAAVQGLGACSMSGDELTELLAGITGTEVDCLRACQEQIEAA 250
>gi|153791755 cyclin domain containing [Homo sapiens]
Length = 350
Score = 99.8 bits (247), Expect = 5e-21
Identities = 62/201 (30%), Positives = 102/201 (50%), Gaps = 10/201 (4%)
Query: 204 DVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAE 263
D+ +Y + Y + + E P+ + +QP +T R L+ WL+ V ++ L E
Sbjct: 94 DLQTFRDYGQSCYAFRKAQESHFHPR-EALARQPQVTAESRCKLLSWLIPVHRQFGLSFE 152
Query: 264 TLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQ 323
+L L VN LDRFL+ V QL+G ++L+A K E++PP V + + + ++++Q
Sbjct: 153 SLCLTVNTLDRFLTTTPVAADCFQLLGVTSLLIACKQVEVHPPRVKQLLALCCGAFSRQQ 212
Query: 324 LLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQ--------GVCVRTENLAKYVAELSLLE 375
L +E ++L L F L PT + FL + + + + LA+ VAELSL +
Sbjct: 213 LCNLECIVLHKLHFTLGAPTISFFLEHFTHARVEAGQAEASEALEAQALARGVAELSLAD 272
Query: 376 ADPFLKYLPSLIAAAAFCLAN 396
F Y PSL+A LA+
Sbjct: 273 Y-AFTSYSPSLLAICCLALAD 292
>gi|16950655 cyclin D1 [Homo sapiens]
Length = 295
Score = 93.2 bits (230), Expect = 4e-19
Identities = 59/192 (30%), Positives = 100/192 (52%), Gaps = 4/192 (2%)
Query: 213 EEIYQYLREAEIRHRPKAHYMK-KQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNF 271
+ + + + +AE P Y K Q ++ MR I+ W++EV EE K E LA+N+
Sbjct: 25 DRVLRAMLKAEETCAPSVSYFKCVQKEVLPSMRKIVATWMLEVCEEQKCEEEVFPLAMNY 84
Query: 272 LDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLL 331
LDRFLS V + +LQL+G M +ASK +E P ++ TD++ +LL+ME LL
Sbjct: 85 LDRFLSLEPVKKSRLQLLGATCMFVASKMKETIPLTAEKLCIYTDNSIRPEELLQMELLL 144
Query: 332 LKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAE--LSLLEAD-PFLKYLPSLIA 388
+ L ++L T + F+ +L + + + + A+ ++L D F+ PS++A
Sbjct: 145 VNKLKWNLAAMTPHDFIEHFLSKMPEAEENKQIIRKHAQTFVALCATDVKFISNPPSMVA 204
Query: 389 AAAFCLANYTVN 400
A + A +N
Sbjct: 205 AGSVVAAVQGLN 216
>gi|242247025 cyclin N-terminal domain containing 2 isoform 2 [Homo
sapiens]
Length = 307
Score = 91.3 bits (225), Expect = 2e-18
Identities = 73/204 (35%), Positives = 104/204 (50%), Gaps = 14/204 (6%)
Query: 196 EDISSLGTDVINVTEYAEEIYQYL---REAEIRHRPKAHYMKKQPDITEGMRTILVDWLV 252
E +S+LG EYA +I+ + R +R P+A +T MR ++VDWLV
Sbjct: 67 EALSALGLQ--GEREYAGDIFAEVMVCRVLPLRALPRA--------VTPEMRALVVDWLV 116
Query: 253 EVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFV 312
+V E L +TLYLAV+ LD +LS V +LQL+G A + +A K EE PE
Sbjct: 117 QVHEYLGLAGDTLYLAVHLLDSYLSAGRVRLHRLQLLGVACLFVACKMEECVLPEPAFLC 176
Query: 313 YITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELS 372
++ D++++ +LL+ E +L L F L P L G + LA Y ELS
Sbjct: 177 LLSADSFSRAELLRAERRILSRLDFRLHHPGPLLCLGLLAALAGSSPQVMLLATYFLELS 236
Query: 373 LLEADPFLKYLPSLIAAAAFCLAN 396
LLEA+ + P AAAA LA+
Sbjct: 237 LLEAEA-AGWEPGRRAAAALSLAH 259
>gi|4502617 cyclin D2 [Homo sapiens]
Length = 289
Score = 88.2 bits (217), Expect = 1e-17
Identities = 63/189 (33%), Positives = 98/189 (51%), Gaps = 8/189 (4%)
Query: 213 EEIYQYLREAEIRHRPKAHYMK-KQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNF 271
+ + Q L E R+ P+ Y K Q DI MR ++ W++EV EE K E LA+N+
Sbjct: 24 DRVLQNLLTIEERYLPQCSYFKCVQKDIQPYMRRMVATWMLEVCEEQKCEEEVFPLAMNY 83
Query: 272 LDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLL 331
LDRFL+ + + LQL+G M LASK +E P ++ TD++ ++LL+ E ++
Sbjct: 84 LDRFLAGVPTPKSHLQLLGAVCMFLASKLKETSPLTAEKLCIYTDNSIKPQELLEWELVV 143
Query: 332 LKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAE--LSLLEAD-PFLKYLPSLIA 388
L L ++L T + F+ LR+ +L + A+ ++L D F Y PS+IA
Sbjct: 144 LGKLKWNLAAVTPHDFIEHILRKLPQQREKLSLIRKHAQTFIALCATDFKFAMYPPSMIA 203
Query: 389 ----AAAFC 393
AA C
Sbjct: 204 TGSVGAAIC 212
>gi|197276674 cyclin J isoform 1 [Homo sapiens]
Length = 383
Score = 77.8 bits (190), Expect = 2e-14
Identities = 72/243 (29%), Positives = 111/243 (45%), Gaps = 34/243 (13%)
Query: 210 EYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAV 269
+ A +I+Q LR E++ Y + P ++ +R D + V + L +LAV
Sbjct: 11 QLAADIHQALRYKELK---LPSYKGQSPQLS--LRRYFADLIAIVSNRFTLCPSARHLAV 65
Query: 270 NFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYP--PEVDEFVYITDDT-----YTKR 322
LD F+ + +L LV + +LLASK+EE P++++ + T TK+
Sbjct: 66 YLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQ 125
Query: 323 QLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRR-----------QGVCVRTENL-----AK 366
LL ME LLL+ ++L +PT F+ YL +C+ L A
Sbjct: 126 NLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMAKYAD 185
Query: 367 YVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHF---WPETLAAFTGYSLSEIVPCL 423
Y E+SL + FL Y PSL+AAA C+A+ + WP L T YS +V C+
Sbjct: 186 YFLEVSLQDY-AFLNYAPSLVAAA--CVASSRIILRLSPTWPTRLHRLTAYSWDFLVQCI 242
Query: 424 SEL 426
L
Sbjct: 243 ERL 245
>gi|209862835 cyclin D3 isoform 1 [Homo sapiens]
Length = 211
Score = 72.8 bits (177), Expect = 6e-13
Identities = 56/169 (33%), Positives = 82/169 (48%), Gaps = 8/169 (4%)
Query: 269 VNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKME 328
+N+LDR+LSC+ + +LQL+G MLLASK E P +++ TD + RQL E
Sbjct: 1 MNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPRQLRDWE 60
Query: 329 HLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAE--LSLLEAD-PFLKYLPS 385
L+L L +DL + FL L R + + L K A+ L+L D F Y PS
Sbjct: 61 VLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKKHAQTFLALCATDYTFAMYPPS 120
Query: 386 LIA-----AAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSELHKA 429
+IA AA L +++ E LA TG + + C ++ A
Sbjct: 121 MIATGSIGAAVQGLGACSMSGDELTELLAGITGTEVDCLRACQEQIEAA 169
>gi|40254889 cyclin J isoform 2 [Homo sapiens]
Length = 372
Score = 65.9 bits (159), Expect = 8e-11
Identities = 70/240 (29%), Positives = 107/240 (44%), Gaps = 39/240 (16%)
Query: 210 EYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAV 269
+ A +I+Q LR E++ Y + P ++ +R D + V + L +LAV
Sbjct: 11 QLAADIHQALRYKELK---LPSYKGQSPQLS--LRRYFADLIAIVSNRFTLCPSARHLAV 65
Query: 270 NFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYP--PEVDEFVYITDDT-----YTKR 322
LD F+ + +L LV + +LLASK+EE P++++ + T TK+
Sbjct: 66 YLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQ 125
Query: 323 QLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRR-----------QGVCVRTENL--AKYVA 369
LL ME LLL+ ++L +PT F+ YL +C+ L AKY
Sbjct: 126 NLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMAKY-- 183
Query: 370 ELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHF---WPETLAAFTGYSLSEIVPCLSEL 426
AD FL+ SL AAA C+A+ + WP L T YS +V C+ L
Sbjct: 184 ------ADYFLEV--SLQVAAA-CVASSRIILRLSPTWPTRLHRLTAYSWDFLVQCIERL 234
>gi|197276676 cyclin J isoform 3 [Homo sapiens]
Length = 371
Score = 65.5 bits (158), Expect = 1e-10
Identities = 63/231 (27%), Positives = 101/231 (43%), Gaps = 22/231 (9%)
Query: 210 EYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAV 269
+ A +I+Q LR E++ Y + P ++ +R D + V + L +LAV
Sbjct: 11 QLAADIHQALRYKELK---LPSYKGQSPQLS--LRRYFADLIAIVSNRFTLCPSARHLAV 65
Query: 270 NFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYP--PEVDEFVYITDDT-----YTKR 322
LD F+ + +L LV + +LLASK+EE P++++ + T TK+
Sbjct: 66 YLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQ 125
Query: 323 QLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENL----AKYVAELSLLEADP 378
LL ME LLL+ ++L +PT F+ YL V +L E + L
Sbjct: 126 NLLHMELLLLETFQWNLCLPTAAHFIEYYLSE---AVHETDLHDGWPMICLEKTKLYMAK 182
Query: 379 FLKYLPSLIAAAAFCLANYTVNKHF---WPETLAAFTGYSLSEIVPCLSEL 426
+ Y + AA C+A+ + WP L T YS +V C+ L
Sbjct: 183 YADYFLEVSLQAAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQCIERL 233
>gi|40805832 cyclin G1 [Homo sapiens]
Length = 295
Score = 54.7 bits (130), Expect = 2e-07
Identities = 58/208 (27%), Positives = 96/208 (46%), Gaps = 17/208 (8%)
Query: 204 DVINVTEYAEEIYQY--LREAEIRHRPKA---HYMKKQPD----ITEGMRTILVDWLVEV 254
+V+ T+ + ++Q L E E R +PK ++ D +T +R V L+ +
Sbjct: 3 EVLTTTDSQKLLHQLNALLEQESRCQPKVCGLRLIESAHDNGLRMTARLRDFEVKDLLSL 62
Query: 255 GEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASK--YEEIYPPEVDEFV 312
+ + ET LAVN LDRFLS M V L VG + LA K EE P + +
Sbjct: 63 TQFFGFDTETFSLAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATDLI 122
Query: 313 YITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQY--LRRQGVCVRTENLAKYVAE 370
I+ +T L++ME ++L+ + + + T QFL Y L ++ + + N +
Sbjct: 123 RISQYRFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSLLQENLPLERRNSINFERL 182
Query: 371 LSLLEADP----FLKYLPSLIAAAAFCL 394
+ L+A F K PS++A + L
Sbjct: 183 EAQLKACHCRIIFSKAKPSVLALSIIAL 210
>gi|4757934 cyclin G1 [Homo sapiens]
Length = 295
Score = 54.7 bits (130), Expect = 2e-07
Identities = 58/208 (27%), Positives = 96/208 (46%), Gaps = 17/208 (8%)
Query: 204 DVINVTEYAEEIYQY--LREAEIRHRPKA---HYMKKQPD----ITEGMRTILVDWLVEV 254
+V+ T+ + ++Q L E E R +PK ++ D +T +R V L+ +
Sbjct: 3 EVLTTTDSQKLLHQLNALLEQESRCQPKVCGLRLIESAHDNGLRMTARLRDFEVKDLLSL 62
Query: 255 GEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASK--YEEIYPPEVDEFV 312
+ + ET LAVN LDRFLS M V L VG + LA K EE P + +
Sbjct: 63 TQFFGFDTETFSLAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATDLI 122
Query: 313 YITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQY--LRRQGVCVRTENLAKYVAE 370
I+ +T L++ME ++L+ + + + T QFL Y L ++ + + N +
Sbjct: 123 RISQYRFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSLLQENLPLERRNSINFERL 182
Query: 371 LSLLEADP----FLKYLPSLIAAAAFCL 394
+ L+A F K PS++A + L
Sbjct: 183 EAQLKACHCRIIFSKAKPSVLALSIIAL 210
>gi|4757936 cyclin G2 [Homo sapiens]
Length = 344
Score = 53.5 bits (127), Expect = 4e-07
Identities = 50/168 (29%), Positives = 75/168 (44%), Gaps = 16/168 (9%)
Query: 242 GMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKY- 300
G+R V+ L + + ET LAVN LDRFL+ M V L +G + LLA++
Sbjct: 54 GLRNAKVEDLRSLANFFGSCTETFVLAVNILDRFLALMKVKPKHLSCIGVCSFLLAARIV 113
Query: 301 -EEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCV 359
E+ P + + I+ T + +ME ++ + L ++L T FL Y +C
Sbjct: 114 EEDCNIPSTHDVIRISQCKCTASDIKRMEKIISEKLHYELEATTALNFLHLY-HTIILCH 172
Query: 360 RTENLAKYVAELSLLEAD--------PFLKYLPSLIAAAAFCLANYTV 399
+E K + L LEA F K PS++ A CL N V
Sbjct: 173 TSER--KEILSLDKLEAQLKACNCRLIFSKAKPSVL---ALCLLNLEV 215
>gi|5802992 cyclin I [Homo sapiens]
Length = 377
Score = 46.2 bits (108), Expect = 6e-05
Identities = 33/132 (25%), Positives = 62/132 (46%), Gaps = 5/132 (3%)
Query: 220 REAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCM 279
REA++ + M +++ R ++ WL ++ ++ L ET LA + LDRFL+ +
Sbjct: 22 REAQM-WKVNVRKMPSNQNVSPSQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATV 80
Query: 280 SVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTY---TKRQLLKMEHLLLKVLA 336
L + + LA+K E + + D++ + ++L+ME ++L L
Sbjct: 81 KAHPKYLSCIAISCFFLAAKTVE-EDERIPVLKVLARDSFCGCSSSEILRMERIILDKLN 139
Query: 337 FDLTVPTTNQFL 348
+DL T FL
Sbjct: 140 WDLHTATPLDFL 151
>gi|94680985 cyclin J-like [Homo sapiens]
Length = 435
Score = 45.8 bits (107), Expect = 8e-05
Identities = 37/133 (27%), Positives = 59/133 (44%), Gaps = 23/133 (17%)
Query: 318 TYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYL-------------------RRQGVC 358
T TK++LL E LLL+ +++L +PT FL YL R+ C
Sbjct: 169 TLTKKELLSTELLLLEAFSWNLCLPTPAHFLDYYLLASVSQKDHHCHTWPTTCPRKTKEC 228
Query: 359 VRTENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTVN-KHFWPETLAAFTGYSLS 417
++ A Y E++ L+ F K+ PS++AAA + + +W L + YSL
Sbjct: 229 LK--EYAHYFLEVT-LQDHIFYKFQPSVVAAACVGASRICLQLSPYWTRDLQRISSYSLE 285
Query: 418 EIVPCLSELHKAY 430
+ C+ L Y
Sbjct: 286 HLSTCIEILLVVY 298
>gi|89886237 cyclin I family, member 2 [Homo sapiens]
Length = 369
Score = 45.1 bits (105), Expect = 1e-04
Identities = 32/117 (27%), Positives = 54/117 (46%), Gaps = 3/117 (2%)
Query: 234 KKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAA 293
K Q +I + +++ WL+ + + T LA+ R L + V L +
Sbjct: 141 KPQDEICDAFEEVVL-WLLRLQNTFYFSQSTFNLALTIFGRLLISVKVKEKYLHCATITS 199
Query: 294 MLLASKY--EEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFL 348
+ LA+K EE + P+V +F Y+ +LL+ME +L L +DL + T FL
Sbjct: 200 LRLAAKVNEEEEFIPQVKDFTKHYGSDYSPNELLRMELAILDRLHWDLYIGTPLDFL 256
>gi|150417989 cyclin K isoform 1 [Homo sapiens]
Length = 580
Score = 40.4 bits (93), Expect = 0.003
Identities = 31/117 (26%), Positives = 51/117 (43%), Gaps = 14/117 (11%)
Query: 250 WLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVD 309
++ +VG L +TL + + RF S + + G + LA K EE D
Sbjct: 56 FIFDVGTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGACCLFLAGKVEETPKKCKD 115
Query: 310 ------------EFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRR 354
+F DD K +++ +E +LL+ + FDL V QFLL+Y ++
Sbjct: 116 IIKTARSLLNDVQFGQFGDDP--KEEVMVLERILLQTIKFDLQVEHPYQFLLKYAKQ 170
>gi|38176158 cyclin K isoform 2 [Homo sapiens]
Length = 354
Score = 40.4 bits (93), Expect = 0.003
Identities = 31/117 (26%), Positives = 51/117 (43%), Gaps = 14/117 (11%)
Query: 250 WLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVD 309
++ +VG L +TL + + RF S + + G + LA K EE D
Sbjct: 56 FIFDVGTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGACCLFLAGKVEETPKKCKD 115
Query: 310 ------------EFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRR 354
+F DD K +++ +E +LL+ + FDL V QFLL+Y ++
Sbjct: 116 IIKTARSLLNDVQFGQFGDDP--KEEVMVLERILLQTIKFDLQVEHPYQFLLKYAKQ 170
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.137 0.411
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,699,862
Number of Sequences: 37866
Number of extensions: 861973
Number of successful extensions: 1901
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 1837
Number of HSP's gapped (non-prelim): 48
length of query: 465
length of database: 18,247,518
effective HSP length: 106
effective length of query: 359
effective length of database: 14,233,722
effective search space: 5109906198
effective search space used: 5109906198
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.