Guide to the Human Genome
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Search of human proteins with 4502013

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4502013 adenylate kinase 2 isoform a [Homo sapiens]
         (239 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4502013 adenylate kinase 2 isoform a [Homo sapiens]                476   e-135
gi|7524346 adenylate kinase 2 isoform b [Homo sapiens]                460   e-130
gi|19923437 adenylate kinase 3 [Homo sapiens]                         174   6e-44
gi|53832001 adenylate kinase 3-like 1 isoform 7 [Homo sapiens]        156   2e-38
gi|53832003 adenylate kinase 3-like 1 isoform 5 [Homo sapiens]        156   2e-38
gi|8051579 adenylate kinase 3-like 1 isoform 6 [Homo sapiens]         156   2e-38
gi|4502011 adenylate kinase 1 [Homo sapiens]                          104   8e-23
gi|7706497 UMP-CMP kinase 1 isoform a [Homo sapiens]                   95   5e-20
gi|28144897 adenylate kinase 5 isoform 1 [Homo sapiens]                87   1e-17
gi|28144899 adenylate kinase 5 isoform 2 [Homo sapiens]                87   1e-17
gi|22749187 putative adenylate kinase-like protein C9orf98 [Homo...    82   5e-16
gi|237858799 adenylate kinase domain containing 1 isoform 1 [Hom...    62   6e-10
gi|21450759 adenylate kinase domain containing 1 isoform 2 [Homo...    62   6e-10
gi|209915597 UMP-CMP kinase 1 isoform b [Homo sapiens]                 59   3e-09
gi|148727333 adenylate kinase 7 [Homo sapiens]                         48   9e-06
gi|145699133 KPL2 protein isoform 1 [Homo sapiens]                     39   0.003
gi|24430151 proteasome 26S ATPase subunit 1 [Homo sapiens]             35   0.044
gi|4506209 proteasome 26S ATPase subunit 2 [Homo sapiens]              33   0.29 
gi|42544174 deoxythymidylate kinase (thymidylate kinase) [Homo s...    31   1.1  
gi|7706557 chromosome 9 open reading frame 78 [Homo sapiens]           30   1.8  
gi|31377591 sestrin 3 [Homo sapiens]                                   30   2.4  
gi|239757701 PREDICTED: hypothetical protein XP_002345525 [Homo ...    29   3.2  
gi|239752186 PREDICTED: hypothetical protein [Homo sapiens]            29   3.2  
gi|239746709 PREDICTED: hypothetical protein XP_002343816 [Homo ...    29   3.2  
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    29   3.2  
gi|40806170 spastin isoform 2 [Homo sapiens]                           29   3.2  
gi|11875211 spastin isoform 1 [Homo sapiens]                           29   3.2  
gi|116642889 cyclic nucleotide gated channel beta 3 [Homo sapiens]     29   3.2  
gi|75677365 dynein heavy chain domain 3 [Homo sapiens]                 29   4.1  
gi|239747656 PREDICTED: similar to mCG116201 [Homo sapiens]            28   7.0  

>gi|4502013 adenylate kinase 2 isoform a [Homo sapiens]
          Length = 239

 Score =  476 bits (1226), Expect = e-135
 Identities = 239/239 (100%), Positives = 239/239 (100%)

Query: 1   MAPSVPAAEPEYPKGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSEL 60
           MAPSVPAAEPEYPKGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSEL
Sbjct: 1   MAPSVPAAEPEYPKGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSEL 60

Query: 61  GKKLKATMDAGKLVSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKE 120
           GKKLKATMDAGKLVSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKE
Sbjct: 61  GKKLKATMDAGKLVSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKE 120

Query: 121 KLDSVIEFSIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNE 180
           KLDSVIEFSIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNE
Sbjct: 121 KLDSVIEFSIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNE 180

Query: 181 KALKIRLQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAAFSKATCKDLVMFI 239
           KALKIRLQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAAFSKATCKDLVMFI
Sbjct: 181 KALKIRLQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAAFSKATCKDLVMFI 239


>gi|7524346 adenylate kinase 2 isoform b [Homo sapiens]
          Length = 232

 Score =  460 bits (1183), Expect = e-130
 Identities = 231/231 (100%), Positives = 231/231 (100%)

Query: 1   MAPSVPAAEPEYPKGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSEL 60
           MAPSVPAAEPEYPKGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSEL
Sbjct: 1   MAPSVPAAEPEYPKGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSEL 60

Query: 61  GKKLKATMDAGKLVSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKE 120
           GKKLKATMDAGKLVSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKE
Sbjct: 61  GKKLKATMDAGKLVSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKE 120

Query: 121 KLDSVIEFSIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNE 180
           KLDSVIEFSIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNE
Sbjct: 121 KLDSVIEFSIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNE 180

Query: 181 KALKIRLQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAAFSKAT 231
           KALKIRLQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAAFSKAT
Sbjct: 181 KALKIRLQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAAFSKAT 231


>gi|19923437 adenylate kinase 3 [Homo sapiens]
          Length = 227

 Score =  174 bits (441), Expect = 6e-44
 Identities = 89/200 (44%), Positives = 134/200 (67%), Gaps = 6/200 (3%)

Query: 16  IRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELGKKLKATMDAGKLVS 75
           +RAV++G PG+GKGT + R+  +F + HL++GD+LR  +  G+E+G   KA +D GKL+ 
Sbjct: 8   LRAVIMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGTEIGVLAKAFIDQGKLIP 67

Query: 76  DEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIPDSLL 135
           D+++  L    L+  L +  +LLDGFPRT+ QAE LD     R  ++D+VI  ++P  ++
Sbjct: 68  DDVMTRLALHELKN-LTQYSWLLDGFPRTLPQAEALD-----RAYQIDTVINLNVPFEVI 121

Query: 136 IRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIRLQAYHTQTT 195
            +R+T R IHP SGR Y+ EFNPPK    DD+TGEPLI+R DD  + +  RL+AY  QT 
Sbjct: 122 KQRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEDQTK 181

Query: 196 PLIEYYRKRGIHSAIDASQT 215
           P++EYY+K+G+      ++T
Sbjct: 182 PVLEYYQKKGVLETFSGTET 201


>gi|53832001 adenylate kinase 3-like 1 isoform 7 [Homo sapiens]
          Length = 223

 Score =  156 bits (394), Expect = 2e-38
 Identities = 84/202 (41%), Positives = 125/202 (61%), Gaps = 6/202 (2%)

Query: 14  KGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELGKKLKATMDAGKL 73
           K +RAV+LGPPG+GKGT   R+A+NF + HL++G  LR  + + +E+G+  K  ++   L
Sbjct: 4   KLLRAVILGPPGSGKGTVCQRIAQNFGLQHLSSGHFLRENIKASTEVGEMAKQYIEKSLL 63

Query: 74  VSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIPDS 133
           V D ++  L+   LE    ++ +LLDGFPRT+ QAE LD + E     +D VI  +IP  
Sbjct: 64  VPDHVITRLMMSELENRRGQH-WLLDGFPRTLGQAEALDKICE-----VDLVISLNIPFE 117

Query: 134 LLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIRLQAYHTQ 193
            L  R++ R IHP SGR Y+ +FNPP     DD+TGEPL+++ DD  +A+  RL+ Y   
Sbjct: 118 TLKDRLSRRWIHPPSGRVYNLDFNPPHVHGIDDVTGEPLVQQEDDKPEAVAARLRQYKDV 177

Query: 194 TTPLIEYYRKRGIHSAIDASQT 215
             P+IE Y+ RG+      ++T
Sbjct: 178 AKPVIELYKSRGVLHQFSGTET 199


>gi|53832003 adenylate kinase 3-like 1 isoform 5 [Homo sapiens]
          Length = 223

 Score =  156 bits (394), Expect = 2e-38
 Identities = 84/202 (41%), Positives = 125/202 (61%), Gaps = 6/202 (2%)

Query: 14  KGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELGKKLKATMDAGKL 73
           K +RAV+LGPPG+GKGT   R+A+NF + HL++G  LR  + + +E+G+  K  ++   L
Sbjct: 4   KLLRAVILGPPGSGKGTVCQRIAQNFGLQHLSSGHFLRENIKASTEVGEMAKQYIEKSLL 63

Query: 74  VSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIPDS 133
           V D ++  L+   LE    ++ +LLDGFPRT+ QAE LD + E     +D VI  +IP  
Sbjct: 64  VPDHVITRLMMSELENRRGQH-WLLDGFPRTLGQAEALDKICE-----VDLVISLNIPFE 117

Query: 134 LLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIRLQAYHTQ 193
            L  R++ R IHP SGR Y+ +FNPP     DD+TGEPL+++ DD  +A+  RL+ Y   
Sbjct: 118 TLKDRLSRRWIHPPSGRVYNLDFNPPHVHGIDDVTGEPLVQQEDDKPEAVAARLRQYKDV 177

Query: 194 TTPLIEYYRKRGIHSAIDASQT 215
             P+IE Y+ RG+      ++T
Sbjct: 178 AKPVIELYKSRGVLHQFSGTET 199


>gi|8051579 adenylate kinase 3-like 1 isoform 6 [Homo sapiens]
          Length = 223

 Score =  156 bits (394), Expect = 2e-38
 Identities = 84/202 (41%), Positives = 125/202 (61%), Gaps = 6/202 (2%)

Query: 14  KGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELGKKLKATMDAGKL 73
           K +RAV+LGPPG+GKGT   R+A+NF + HL++G  LR  + + +E+G+  K  ++   L
Sbjct: 4   KLLRAVILGPPGSGKGTVCQRIAQNFGLQHLSSGHFLRENIKASTEVGEMAKQYIEKSLL 63

Query: 74  VSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIPDS 133
           V D ++  L+   LE    ++ +LLDGFPRT+ QAE LD + E     +D VI  +IP  
Sbjct: 64  VPDHVITRLMMSELENRRGQH-WLLDGFPRTLGQAEALDKICE-----VDLVISLNIPFE 117

Query: 134 LLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIRLQAYHTQ 193
            L  R++ R IHP SGR Y+ +FNPP     DD+TGEPL+++ DD  +A+  RL+ Y   
Sbjct: 118 TLKDRLSRRWIHPPSGRVYNLDFNPPHVHGIDDVTGEPLVQQEDDKPEAVAARLRQYKDV 177

Query: 194 TTPLIEYYRKRGIHSAIDASQT 215
             P+IE Y+ RG+      ++T
Sbjct: 178 AKPVIELYKSRGVLHQFSGTET 199


>gi|4502011 adenylate kinase 1 [Homo sapiens]
          Length = 194

 Score =  104 bits (259), Expect = 8e-23
 Identities = 65/205 (31%), Positives = 107/205 (52%), Gaps = 32/205 (15%)

Query: 20  LLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELGKKLKATMDAGKLVSDEMV 79
           ++G PG+GKGTQ  ++ + +   HL+TGD+LR+ V+SGS  GKKL   M+ G+LV  E V
Sbjct: 13  VVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRSEVSSGSARGKKLSEIMEKGQLVPLETV 72

Query: 80  VELIEKNLETPL-CKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIPDSLLIRR 138
           ++++   +   +    GFL+DG+PR V+Q E      E+R  +   ++        + +R
Sbjct: 73  LDMLRDAMVAKVNTSKGFLIDGYPREVQQGEE----FERRIGQPTLLLYVDAGPETMTQR 128

Query: 139 ITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIRLQAYHTQTTPLI 198
           +  R                       + +G     R DDNE+ +K RL+ Y+  T P+I
Sbjct: 129 LLKR----------------------GETSG-----RVDDNEETIKKRLETYYKATEPVI 161

Query: 199 EYYRKRGIHSAIDASQTPDVVFASI 223
            +Y KRGI   ++A  + D VF+ +
Sbjct: 162 AFYEKRGIVRKVNAEGSVDSVFSQV 186


>gi|7706497 UMP-CMP kinase 1 isoform a [Homo sapiens]
          Length = 228

 Score = 95.1 bits (235), Expect = 5e-20
 Identities = 67/225 (29%), Positives = 108/225 (48%), Gaps = 33/225 (14%)

Query: 10  PEYPKGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLR-AMVASGSELGKKLKATM 68
           P   K +   +LG PGAGKGTQ  R+ E +   HL+ G++LR       S+ G+ ++  +
Sbjct: 30  PRLMKPLVVFVLGGPGAGKGTQCARIVEKYGYTHLSAGELLRDERKNPDSQYGELIEKYI 89

Query: 69  DAGKLVSDEMVVELIEKNLETPLC----KNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDS 124
             GK+V  E+ + L+++ ++  +     KN FL+DGFPR     +  +  M+  K  +  
Sbjct: 90  KEGKIVPVEITISLLKREMDQTMAANAQKNKFLIDGFPRNQDNLQGWNKTMD-GKADVSF 148

Query: 125 VIEFSIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALK 184
           V+ F   + + I R   R      G+S                       RSDDN ++L+
Sbjct: 149 VLFFDCNNEICIERCLER------GKS---------------------SGRSDDNRESLE 181

Query: 185 IRLQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAAFSK 229
            R+Q Y   T P+I+ Y + G    IDAS++ D VF  ++  F K
Sbjct: 182 KRIQTYLQSTKPIIDLYEEMGKVKKIDASKSVDEVFDEVVQIFDK 226


>gi|28144897 adenylate kinase 5 isoform 1 [Homo sapiens]
          Length = 562

 Score = 87.0 bits (214), Expect = 1e-17
 Identities = 63/208 (30%), Positives = 98/208 (47%), Gaps = 32/208 (15%)

Query: 20  LLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELGKKLKATMDAGKLVSDEMV 79
           ++G PG+GKGTQ  +L E +   HL+TG++LR  +AS SE  K ++  M+ G LV   +V
Sbjct: 381 IIGGPGSGKGTQCEKLVEKYGFTHLSTGELLREELASESERSKLIRDIMERGDLVPSGIV 440

Query: 80  VELIEKNLETPL-CKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIPDSLLIRR 138
           +EL+++ +   L    GFL+DG+PR V+Q E       +R      VI        +  R
Sbjct: 441 LELLKEAMVASLGDTRGFLIDGYPREVKQGEEFG----RRIGDPQLVICMDCSADTMTNR 496

Query: 139 ITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIRLQAYHTQTTPLI 198
           +  R              +    P+             DD  K +  RL+AY+  + P+I
Sbjct: 497 LLQR--------------SRSSLPV-------------DDTTKTIAKRLEAYYRASIPVI 529

Query: 199 EYYRKRGIHSAIDASQTPDVVFASILAA 226
            YY  +     I+A  TP+ VF  +  A
Sbjct: 530 AYYETKTQLHKINAEGTPEDVFLQLCTA 557



 Score = 77.0 bits (188), Expect = 1e-14
 Identities = 54/220 (24%), Positives = 99/220 (45%), Gaps = 33/220 (15%)

Query: 9   EPEYPKGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELGK--KLKA 66
           +P  P+    +++G PG+GKGTQ+ ++AE +   +++ G++LR  + S S   K   +  
Sbjct: 126 DPTRPRPKIILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSTSSNRKWSLIAK 185

Query: 67  TMDAGKLVSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVI 126
            +  G+L   E  +  I++ L     + G ++DGFPR V QA   +D             
Sbjct: 186 IITTGELAPQETTITEIKQKLMQIPDEEGIVIDGFPRDVAQALSFED------------- 232

Query: 127 EFSIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIR 186
           +   PD ++      + +  +  +   ++  P                  DDN KA + R
Sbjct: 233 QICTPDLVVFLACANQRLKERLLKRAEQQGRP------------------DDNVKATQRR 274

Query: 187 LQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAA 226
           L  +     PL++Y++++G+    DA +  D VF  I  A
Sbjct: 275 LMNFKQNAAPLVKYFQEKGLIMTFDADRDEDEVFYDISMA 314


>gi|28144899 adenylate kinase 5 isoform 2 [Homo sapiens]
          Length = 536

 Score = 87.0 bits (214), Expect = 1e-17
 Identities = 63/208 (30%), Positives = 98/208 (47%), Gaps = 32/208 (15%)

Query: 20  LLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELGKKLKATMDAGKLVSDEMV 79
           ++G PG+GKGTQ  +L E +   HL+TG++LR  +AS SE  K ++  M+ G LV   +V
Sbjct: 355 IIGGPGSGKGTQCEKLVEKYGFTHLSTGELLREELASESERSKLIRDIMERGDLVPSGIV 414

Query: 80  VELIEKNLETPL-CKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIPDSLLIRR 138
           +EL+++ +   L    GFL+DG+PR V+Q E       +R      VI        +  R
Sbjct: 415 LELLKEAMVASLGDTRGFLIDGYPREVKQGEEFG----RRIGDPQLVICMDCSADTMTNR 470

Query: 139 ITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIRLQAYHTQTTPLI 198
           +  R              +    P+             DD  K +  RL+AY+  + P+I
Sbjct: 471 LLQR--------------SRSSLPV-------------DDTTKTIAKRLEAYYRASIPVI 503

Query: 199 EYYRKRGIHSAIDASQTPDVVFASILAA 226
            YY  +     I+A  TP+ VF  +  A
Sbjct: 504 AYYETKTQLHKINAEGTPEDVFLQLCTA 531



 Score = 77.0 bits (188), Expect = 1e-14
 Identities = 54/220 (24%), Positives = 99/220 (45%), Gaps = 33/220 (15%)

Query: 9   EPEYPKGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELGK--KLKA 66
           +P  P+    +++G PG+GKGTQ+ ++AE +   +++ G++LR  + S S   K   +  
Sbjct: 100 DPTRPRPKIILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSTSSNRKWSLIAK 159

Query: 67  TMDAGKLVSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVI 126
            +  G+L   E  +  I++ L     + G ++DGFPR V QA   +D             
Sbjct: 160 IITTGELAPQETTITEIKQKLMQIPDEEGIVIDGFPRDVAQALSFED------------- 206

Query: 127 EFSIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIR 186
           +   PD ++      + +  +  +   ++  P                  DDN KA + R
Sbjct: 207 QICTPDLVVFLACANQRLKERLLKRAEQQGRP------------------DDNVKATQRR 248

Query: 187 LQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAA 226
           L  +     PL++Y++++G+    DA +  D VF  I  A
Sbjct: 249 LMNFKQNAAPLVKYFQEKGLIMTFDADRDEDEVFYDISMA 288


>gi|22749187 putative adenylate kinase-like protein C9orf98 [Homo
           sapiens]
          Length = 479

 Score = 81.6 bits (200), Expect = 5e-16
 Identities = 55/208 (26%), Positives = 105/208 (50%), Gaps = 12/208 (5%)

Query: 17  RAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELGKKLKATMDAGKLVSD 76
           R +LLGP G+GK  QA  LA+ + + ++  G +L+  VA  +  G+ ++   +    V D
Sbjct: 270 RVLLLGPVGSGKSLQAALLAQKYRLVNVCCGQLLKEAVADRTTFGELIQPFFEKEMAVPD 329

Query: 77  EMVVELIEKNLETPLC-KNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIPDSLL 135
            ++++++ + L+   C + G++L G PR + QA +L+ L        + V   ++P   +
Sbjct: 330 SLLMKVLSQRLDQQDCIQKGWVLHGVPRDLDQAHLLNRL----GYNPNRVFFLNVPFDSI 385

Query: 136 IRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIRLQAYHTQTT 195
           + R+T R I P +G  YH  + PP  P  +      L++   D E+ +K+++  ++  + 
Sbjct: 386 MERLTLRRIDPVTGERYHLMYKPP--PTME--IQARLLQNPKDAEEQVKLKMDLFYRNSA 441

Query: 196 PLIEYYRKRGIHSAIDASQTPDVVFASI 223
            L + Y   G    ++  Q P  VF  I
Sbjct: 442 DLEQLY---GSAITLNGDQDPYTVFEYI 466



 Score = 67.0 bits (162), Expect = 1e-11
 Identities = 63/210 (30%), Positives = 97/210 (46%), Gaps = 16/210 (7%)

Query: 17  RAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELGKKLKATMDAGKLVSD 76
           R V+LGPP +GK T A  L ++     L   +++    +  +   ++L       K V  
Sbjct: 59  RIVILGPPASGKTTIAMWLCKHLNSSLLTLENLILNEFSYTATEARRLYLQR---KTVPS 115

Query: 77  EMVVELIEKNLETPLC-KNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIPDSLL 135
            ++V+LI++ L    C K G++LDG P T  QA  +  L    +     VI  S PD++L
Sbjct: 116 ALLVQLIQERLAEEDCIKQGWILDGIPETREQALRIQTLGITPRH----VIVLSAPDTVL 171

Query: 136 IRRITGRLIHPKSGRSYHEEFN-PPKEPMKDDITGEPLIRRSDDNEKALKIRLQAYHTQT 194
           I R  G+ I P++G  YH  F+ PP+  +++      L+   D +E     +L  YH   
Sbjct: 172 IERNLGKRIDPQTGEIYHTTFDWPPESEIQN-----RLMVPEDISELETAQKLLEYHRNI 226

Query: 195 TPLIEYYRKRGIHSAIDASQTPDVVFASIL 224
             +I  Y K  I   I A Q    VF   L
Sbjct: 227 VRVIPSYPK--ILKVISADQPCVDVFYQAL 254


>gi|237858799 adenylate kinase domain containing 1 isoform 1 [Homo
           sapiens]
          Length = 1911

 Score = 61.6 bits (148), Expect = 6e-10
 Identities = 49/193 (25%), Positives = 92/193 (47%), Gaps = 22/193 (11%)

Query: 14  KGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELGKKLKATMDAGKL 73
           K +  V+ G PG GK T A  + + +    +    +L   +A+ +E G  L++ + +G+ 
Sbjct: 29  KPVCFVVFGKPGVGKTTLARYITQAWKCIRVEALPILEEQIAAETESGVMLQSMLISGQS 88

Query: 74  VSDEMVVELIEKNLETP-LCKNGFLLDGFP-------RTVRQAEMLDDLMEKRKEKLDSV 125
           + DE+V++L+ + L +P +C  G+++   P        T++Q E++ +L      K D +
Sbjct: 89  IPDELVIKLMLEKLNSPEVCHFGYIITEIPSLSQDAMTTLQQIELIKNL----NLKPDVI 144

Query: 126 IEFSIPDSLLIRRITGRLIHPKSGRSY-HEEFNP---------PKEPMKDDITGEPLIRR 175
           I    PD  L +RI+G+  H  +G  Y  ++++P          KE  KD    E     
Sbjct: 145 INIKCPDYDLCQRISGQRQHNNTGYIYSRDQWDPEVIENHRKKKKEAQKDGKGEEEEEEE 204

Query: 176 SDDNEKALKIRLQ 188
             + E+A    +Q
Sbjct: 205 EQEEEEAFIAEMQ 217



 Score = 60.5 bits (145), Expect = 1e-09
 Identities = 39/137 (28%), Positives = 70/137 (51%), Gaps = 9/137 (6%)

Query: 6    PAAEPEYPKGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVAS--GSELGKK 63
            P  +P  P  IR +++GPP +GK T A ++   + + HL+ G  LR ++ +   +EL   
Sbjct: 1404 PKPKPTVP--IRIIIVGPPKSGKTTVAKKITSEYGLKHLSIGGALRYVLNNHPETELALM 1461

Query: 64   LKATMDAGKLVSDEMVVELIEKNLETPLCKN-GFLLDGFPRTVRQAEMLDDLMEKRKEKL 122
            L   +  G    DE+ ++ +E +L   +C   G ++DG+P T  Q     +L+E R    
Sbjct: 1462 LNWHLHKGMTAPDELAIQALELSLMESVCNTAGVVIDGYPVTKHQM----NLLEARSIIP 1517

Query: 123  DSVIEFSIPDSLLIRRI 139
              + E S+P   + +R+
Sbjct: 1518 MVIFELSVPSKEIFKRL 1534



 Score = 33.9 bits (76), Expect = 0.13
 Identities = 36/154 (23%), Positives = 58/154 (37%), Gaps = 49/154 (31%)

Query: 9    EPEYPKGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMV-------------- 54
            EP     +R  L+GP G+GK     +LAE   + H+   ++L+  +              
Sbjct: 985  EPLKAPPLRICLVGPQGSGKTMCGRQLAEKLNIFHIQFEEVLQEKLLLKTEKKVGPEFEE 1044

Query: 55   ------ASGSELGK------------KLKATMDAGKLVSDEMVVE--------------- 81
                  A+  EL +              K  +   +L  +E V++               
Sbjct: 1045 DSENEQAAKQELEELAIQANVKVEEENTKKQLPEVQLTEEEEVIKSSLMENEPLPPEILE 1104

Query: 82   --LIEKNLETPLCKNGFLLDGFPRTVRQAEMLDD 113
              L E  L+ P+   GF+LDGFPR   +A+ L D
Sbjct: 1105 VILSEWWLKEPIRSTGFILDGFPRYPEEAQFLGD 1138


>gi|21450759 adenylate kinase domain containing 1 isoform 2 [Homo
           sapiens]
          Length = 421

 Score = 61.6 bits (148), Expect = 6e-10
 Identities = 49/193 (25%), Positives = 92/193 (47%), Gaps = 22/193 (11%)

Query: 14  KGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELGKKLKATMDAGKL 73
           K +  V+ G PG GK T A  + + +    +    +L   +A+ +E G  L++ + +G+ 
Sbjct: 29  KPVCFVVFGKPGVGKTTLARYITQAWKCIRVEALPILEEQIAAETESGVMLQSMLISGQS 88

Query: 74  VSDEMVVELIEKNLETP-LCKNGFLLDGFP-------RTVRQAEMLDDLMEKRKEKLDSV 125
           + DE+V++L+ + L +P +C  G+++   P        T++Q E++ +L      K D +
Sbjct: 89  IPDELVIKLMLEKLNSPEVCHFGYIITEIPSLSQDAMTTLQQIELIKNL----NLKPDVI 144

Query: 126 IEFSIPDSLLIRRITGRLIHPKSGRSY-HEEFNP---------PKEPMKDDITGEPLIRR 175
           I    PD  L +RI+G+  H  +G  Y  ++++P          KE  KD    E     
Sbjct: 145 INIKCPDYDLCQRISGQRQHNNTGYIYSRDQWDPEVIENHRKKKKEAQKDGKGEEEEEEE 204

Query: 176 SDDNEKALKIRLQ 188
             + E+A    +Q
Sbjct: 205 EQEEEEAFIAEMQ 217


>gi|209915597 UMP-CMP kinase 1 isoform b [Homo sapiens]
          Length = 179

 Score = 59.3 bits (142), Expect = 3e-09
 Identities = 56/220 (25%), Positives = 83/220 (37%), Gaps = 72/220 (32%)

Query: 10  PEYPKGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELGKKLKATMD 69
           P   K +   +LG PGAGKGTQ  R                                   
Sbjct: 30  PRLMKPLVVFVLGGPGAGKGTQCAR----------------------------------- 54

Query: 70  AGKLVSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFS 129
                    +VE +++ +     KN FL+DGFPR     +  +  M+  K  +  V+ F 
Sbjct: 55  ---------IVEEMDQTMAANAQKNKFLIDGFPRNQDNLQGWNKTMD-GKADVSFVLFFD 104

Query: 130 IPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIRLQA 189
             + + I R   R      G+S                       RSDDN ++L+ R+Q 
Sbjct: 105 CNNEICIERCLER------GKS---------------------SGRSDDNRESLEKRIQT 137

Query: 190 YHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAAFSK 229
           Y   T P+I+ Y + G    IDAS++ D VF  ++  F K
Sbjct: 138 YLQSTKPIIDLYEEMGKVKKIDASKSVDEVFDEVVQIFDK 177


>gi|148727333 adenylate kinase 7 [Homo sapiens]
          Length = 723

 Score = 47.8 bits (112), Expect = 9e-06
 Identities = 35/136 (25%), Positives = 65/136 (47%), Gaps = 32/136 (23%)

Query: 16  IRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVAS------------------- 56
           I+  +LGPP  GK + A  LA  + + H+   D++   +A                    
Sbjct: 368 IKICILGPPAVGKSSIAKELANYYKLHHIQLKDVISEAIAKLEAIVAPNDVGEGEEEVEE 427

Query: 57  ---------GSELGKKLKATMD--AGKLVSDEMVVELIEKNLETPLCKN-GFLLDGFPRT 104
                      EL   +K +M+  AG+L  D+ ++  +++ L++  C+N G++LDGFP+T
Sbjct: 428 EEEEENVEDAQELLDGIKESMEQNAGQL-DDQYIIRFMKEKLKSMPCRNQGYILDGFPKT 486

Query: 105 VRQAEMLDDLMEKRKE 120
             QA+ L +  ++ +E
Sbjct: 487 YDQAKDLFNQEDEEEE 502


>gi|145699133 KPL2 protein isoform 1 [Homo sapiens]
          Length = 1822

 Score = 39.3 bits (90), Expect = 0.003
 Identities = 19/68 (27%), Positives = 36/68 (52%)

Query: 58  SELGKKLKATMDAGKLVSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEK 117
           ++LG K +  +  GK + D ++V++I   +         +LDGFP T+ QA++L++ +  
Sbjct: 684 AQLGAKSEQLLKKGKSIPDVLLVDIIVNAINEIPVNQDCILDGFPMTLNQAQLLEEALTG 743

Query: 118 RKEKLDSV 125
               L  V
Sbjct: 744 CNRNLTEV 751


>gi|24430151 proteasome 26S ATPase subunit 1 [Homo sapiens]
          Length = 440

 Score = 35.4 bits (80), Expect = 0.044
 Identities = 47/204 (23%), Positives = 80/204 (39%), Gaps = 47/204 (23%)

Query: 5   VPAAEPEY--------PKGIRAVLLGPPGAGKGTQAPRLAENFCVCHLAT--GDMLRAMV 54
           +P   PEY        PKG+  +L GPPG GK   A  +A       L     ++++  +
Sbjct: 203 LPLTHPEYYEEMGIKPPKGV--ILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYL 260

Query: 55  ASGSELGKKL--KATMDAGKLVSDEMVVEL----------IEKNLETPLCKNGFLLDGFP 102
             G +L ++L   A   A  +V  + +  +           E+ ++  + +    LDGF 
Sbjct: 261 GDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDSNSGGEREIQRTMLELLNQLDGFD 320

Query: 103 --------RTVRQAEMLDDLMEKRKEKLDSVIEFSIPDSLLIRRITGRLIHPKSGRSYHE 154
                       + E LD  +  R  ++D  IEF +PD    +RI               
Sbjct: 321 SRGDVKVIMATNRIETLDPAL-IRPGRIDRKIEFPLPDEKTKKRIF-------------- 365

Query: 155 EFNPPKEPMKDDITGEPLIRRSDD 178
           + +  +  + DD+T + LI   DD
Sbjct: 366 QIHTSRMTLADDVTLDDLIMAKDD 389


>gi|4506209 proteasome 26S ATPase subunit 2 [Homo sapiens]
          Length = 433

 Score = 32.7 bits (73), Expect = 0.29
 Identities = 39/146 (26%), Positives = 65/146 (44%), Gaps = 29/146 (19%)

Query: 11  EYPKGIRAVLLGPPGAGKGTQAPRLAE--NFCVCHLATGDMLRAMVASGSELGKKL---K 65
           E PKG+  +L GPPG GK   A  +A   + C   +   ++++  V  G+ + ++L    
Sbjct: 207 EPPKGV--LLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMA 264

Query: 66  ATMDAGKLVSDEMVVELI-----------EKNLETPLCKNGFLLDGF-PR-------TVR 106
            T  A  +  DE  ++ I           +  ++  + +    LDGF PR          
Sbjct: 265 RTKKACLIFFDE--IDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATN 322

Query: 107 QAEMLDDLMEKRKEKLDSVIEFSIPD 132
           + + LD  +  R  +LD  IEFS+PD
Sbjct: 323 RPDTLDPAL-MRPGRLDRKIEFSLPD 347


>gi|42544174 deoxythymidylate kinase (thymidylate kinase) [Homo
          sapiens]
          Length = 212

 Score = 30.8 bits (68), Expect = 1.1
 Identities = 29/83 (34%), Positives = 39/83 (46%), Gaps = 6/83 (7%)

Query: 14 KGIRAVLLGPPGAGKGTQAPRLAENFCVC-HLATGDMLRAMVASGSELGKKLKATMDAGK 72
          +G   VL G   AGK TQ+ +L E  C   H A  ++LR    S +E+GK L + +    
Sbjct: 5  RGALIVLEGVDRAGKSTQSRKLVEALCAAGHRA--ELLRFPERS-TEIGKLLSSYLQKKS 61

Query: 73 LVSDEMVVELIEKNL--ETPLCK 93
           V D  V  L   N   + PL K
Sbjct: 62 DVEDHSVHLLFSANRWEQVPLIK 84


>gi|7706557 chromosome 9 open reading frame 78 [Homo sapiens]
          Length = 289

 Score = 30.0 bits (66), Expect = 1.8
 Identities = 21/68 (30%), Positives = 32/68 (47%), Gaps = 10/68 (14%)

Query: 114 LMEKRKEKLDSVIEFSIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLI 173
           L E++ +K DS   F +P ++ +  +       +  R YHEE N P    K++    PL 
Sbjct: 198 LAEQQNKKKDSETSF-VPTNMAVNYV-------QHNRFYHEELNAPIRRNKEEPKARPL- 248

Query: 174 RRSDDNEK 181
            R  D EK
Sbjct: 249 -RVGDTEK 255


>gi|31377591 sestrin 3 [Homo sapiens]
          Length = 492

 Score = 29.6 bits (65), Expect = 2.4
 Identities = 21/77 (27%), Positives = 31/77 (40%), Gaps = 20/77 (25%)

Query: 6   PAAEPEYPKGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELG---- 61
           P  +PE   G R + +                NFCVC LA  + +     SGS  G    
Sbjct: 214 PERDPEISNGFRLISVN---------------NFCVCDLANDNNIENASLSGSNFGIVDS 258

Query: 62  -KKLKATMDAGKLVSDE 77
             +L+A M+  K + +E
Sbjct: 259 LSELEALMERMKRLQEE 275


>gi|239757701 PREDICTED: hypothetical protein XP_002345525 [Homo
           sapiens]
          Length = 180

 Score = 29.3 bits (64), Expect = 3.2
 Identities = 14/39 (35%), Positives = 19/39 (48%)

Query: 23  PPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELG 61
           PPG G+G Q           +L +G  L+ M ASG + G
Sbjct: 74  PPGTGRGPQRSPPISRMLDTNLLSGSSLQQMAASGKKAG 112


>gi|239752186 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 180

 Score = 29.3 bits (64), Expect = 3.2
 Identities = 14/39 (35%), Positives = 19/39 (48%)

Query: 23  PPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELG 61
           PPG G+G Q           +L +G  L+ M ASG + G
Sbjct: 74  PPGTGRGPQRSPPISRMLDTNLLSGSSLQQMAASGKKAG 112


>gi|239746709 PREDICTED: hypothetical protein XP_002343816 [Homo
           sapiens]
          Length = 180

 Score = 29.3 bits (64), Expect = 3.2
 Identities = 14/39 (35%), Positives = 19/39 (48%)

Query: 23  PPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELG 61
           PPG G+G Q           +L +G  L+ M ASG + G
Sbjct: 74  PPGTGRGPQRSPPISRMLDTNLLSGSSLQQMAASGKKAG 112


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 29.3 bits (64), Expect = 3.2
 Identities = 17/34 (50%), Positives = 18/34 (52%), Gaps = 2/34 (5%)

Query: 2   APSVPAAEPEYPKGIRAVLLGPPG--AGKGTQAP 33
           AP+ PAA P  P    A L  PPG  AG  T AP
Sbjct: 262 APAAPAAAPPPPPPAPATLARPPGHPAGPPTAAP 295


>gi|40806170 spastin isoform 2 [Homo sapiens]
          Length = 584

 Score = 29.3 bits (64), Expect = 3.2
 Identities = 21/69 (30%), Positives = 32/69 (46%), Gaps = 7/69 (10%)

Query: 5   VPAAEPEYPKGIRA-----VLLGPPGAGKGTQAPRLA--ENFCVCHLATGDMLRAMVASG 57
           +P+  PE   G+RA     +L GPPG GK   A  +A   N    +++   +    V  G
Sbjct: 328 LPSLRPELFTGLRAPARGLLLFGPPGNGKTMLAKAVAAESNATFFNISAASLTSKYVGEG 387

Query: 58  SELGKKLKA 66
            +L + L A
Sbjct: 388 EKLVRALFA 396


>gi|11875211 spastin isoform 1 [Homo sapiens]
          Length = 616

 Score = 29.3 bits (64), Expect = 3.2
 Identities = 21/69 (30%), Positives = 32/69 (46%), Gaps = 7/69 (10%)

Query: 5   VPAAEPEYPKGIRA-----VLLGPPGAGKGTQAPRLA--ENFCVCHLATGDMLRAMVASG 57
           +P+  PE   G+RA     +L GPPG GK   A  +A   N    +++   +    V  G
Sbjct: 360 LPSLRPELFTGLRAPARGLLLFGPPGNGKTMLAKAVAAESNATFFNISAASLTSKYVGEG 419

Query: 58  SELGKKLKA 66
            +L + L A
Sbjct: 420 EKLVRALFA 428


>gi|116642889 cyclic nucleotide gated channel beta 3 [Homo sapiens]
          Length = 809

 Score = 29.3 bits (64), Expect = 3.2
 Identities = 19/78 (24%), Positives = 34/78 (43%)

Query: 135 LIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIRLQAYHTQT 194
           L++R+  R    K      +  +P   P     T  P ++ SDD       RL  +  + 
Sbjct: 135 LVKRMRQRTALYKKKLVEGDLSSPEASPQTAKPTAVPPVKESDDKPTEHYYRLLWFKVKK 194

Query: 195 TPLIEYYRKRGIHSAIDA 212
            PL EY ++  + ++ID+
Sbjct: 195 MPLTEYLKRIKLPNSIDS 212


>gi|75677365 dynein heavy chain domain 3 [Homo sapiens]
          Length = 4427

 Score = 28.9 bits (63), Expect = 4.1
 Identities = 18/77 (23%), Positives = 38/77 (49%), Gaps = 7/77 (9%)

Query: 21   LGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELGKKL----KATMDAGKLVSD 76
            +GPPG G+   +PRL   F + ++      + +   G+ + +KL    +     G +V++
Sbjct: 2531 MGPPGGGRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQDFEEEVKPIGNVVTE 2590

Query: 77   ---EMVVELIEKNLETP 90
               +M   ++++ L TP
Sbjct: 2591 ATLDMYNTVVQRFLPTP 2607


>gi|239747656 PREDICTED: similar to mCG116201 [Homo sapiens]
          Length = 591

 Score = 28.1 bits (61), Expect = 7.0
 Identities = 14/37 (37%), Positives = 19/37 (51%)

Query: 11  EYPKGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATG 47
           E+PK  R   + PPG  +G +AP  A     C +A G
Sbjct: 514 EHPKDGRKGSVHPPGPPRGLRAPPRAAARAPCEMAVG 550


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.136    0.391 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,713,545
Number of Sequences: 37866
Number of extensions: 453093
Number of successful extensions: 1444
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 1377
Number of HSP's gapped (non-prelim): 61
length of query: 239
length of database: 18,247,518
effective HSP length: 99
effective length of query: 140
effective length of database: 14,498,784
effective search space: 2029829760
effective search space used: 2029829760
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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