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Search of human proteins with 44921615
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|44921615 exocyst complex 84-kDa subunit [Homo sapiens]
(725 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|44921615 exocyst complex 84-kDa subunit [Homo sapiens] 1436 0.0
gi|46049114 M-phase phosphoprotein 1 [Homo sapiens] 43 0.001
gi|154240686 FYVE, RhoGEF and PH domain containing 6 [Homo sapiens] 42 0.002
gi|93204881 Rab interacting lysosomal protein [Homo sapiens] 40 0.010
gi|154759293 cysteine-rich hydrophobic domain 1 [Homo sapiens] 39 0.017
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 39 0.022
gi|223671856 coiled-coil domain containing 85C [Homo sapiens] 38 0.038
gi|197313672 carnitine deficiency-associated gene expressed in v... 38 0.038
gi|8923710 carnitine deficiency-associated gene expressed in ven... 38 0.038
gi|110347449 POU domain, class 4, transcription factor 1 [Homo s... 38 0.038
gi|22547197 zinc finger protein of the cerebellum 2 [Homo sapiens] 37 0.049
gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens] 37 0.065
gi|4507693 tuberous sclerosis 1 protein isoform 1 [Homo sapiens] 37 0.084
gi|241666464 tuberous sclerosis 1 protein isoform 4 [Homo sapiens] 37 0.084
gi|241666462 tuberous sclerosis 1 protein isoform 3 [Homo sapiens] 37 0.084
gi|33620755 YEATS domain containing 2 [Homo sapiens] 36 0.11
gi|44890059 involucrin [Homo sapiens] 36 0.14
gi|210032790 hypothetical protein LOC27146 [Homo sapiens] 36 0.14
gi|13775236 scratch [Homo sapiens] 36 0.14
gi|239753428 PREDICTED: hypothetical protein [Homo sapiens] 35 0.19
gi|239747997 PREDICTED: hypothetical protein [Homo sapiens] 35 0.19
gi|22035606 mitogen-activated protein kinase kinase kinase kinas... 35 0.19
gi|22035602 mitogen-activated protein kinase kinase kinase kinas... 35 0.19
gi|51317384 GLE1 RNA export mediator homolog isoform 1 [Homo sap... 35 0.25
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 35 0.25
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 35 0.25
gi|156104874 envoplakin [Homo sapiens] 35 0.25
gi|4557627 GLE1 RNA export mediator homolog isoform 2 [Homo sapi... 35 0.25
gi|194018511 keratin 77 [Homo sapiens] 35 0.32
gi|32967601 ankyrin 3 isoform 1 [Homo sapiens] 35 0.32
>gi|44921615 exocyst complex 84-kDa subunit [Homo sapiens]
Length = 725
Score = 1436 bits (3716), Expect = 0.0
Identities = 725/725 (100%), Positives = 725/725 (100%)
Query: 1 MAMAMSDSGASRLRRQLESGGFEARLYVKQLSQQSDGDRDLQEHRQRIQALAEETAQNLK 60
MAMAMSDSGASRLRRQLESGGFEARLYVKQLSQQSDGDRDLQEHRQRIQALAEETAQNLK
Sbjct: 1 MAMAMSDSGASRLRRQLESGGFEARLYVKQLSQQSDGDRDLQEHRQRIQALAEETAQNLK 60
Query: 61 RNVYQNYRQFIETAREISYLESEMYQLSHLLTEQKSSLESIPLTLLPAAAAAGAAAASGG 120
RNVYQNYRQFIETAREISYLESEMYQLSHLLTEQKSSLESIPLTLLPAAAAAGAAAASGG
Sbjct: 61 RNVYQNYRQFIETAREISYLESEMYQLSHLLTEQKSSLESIPLTLLPAAAAAGAAAASGG 120
Query: 121 EEGVGGAGGRDHLRGQAGFFSTPGGASRDGSGPGEEGKQRTLTTLLEKVEGCRHLLETPG 180
EEGVGGAGGRDHLRGQAGFFSTPGGASRDGSGPGEEGKQRTLTTLLEKVEGCRHLLETPG
Sbjct: 121 EEGVGGAGGRDHLRGQAGFFSTPGGASRDGSGPGEEGKQRTLTTLLEKVEGCRHLLETPG 180
Query: 181 QYLVYNGDLVEYDADHMAQLQRVHGFLMNDCLLVATWLPQRRGMYRYNALYSLDGLAVVN 240
QYLVYNGDLVEYDADHMAQLQRVHGFLMNDCLLVATWLPQRRGMYRYNALYSLDGLAVVN
Sbjct: 181 QYLVYNGDLVEYDADHMAQLQRVHGFLMNDCLLVATWLPQRRGMYRYNALYSLDGLAVVN 240
Query: 241 VKDNPPMKDMFKLLMFPESRIFQAENAKIKREWLEVLEDTKRALSEKRRREQEEAAAPRG 300
VKDNPPMKDMFKLLMFPESRIFQAENAKIKREWLEVLEDTKRALSEKRRREQEEAAAPRG
Sbjct: 241 VKDNPPMKDMFKLLMFPESRIFQAENAKIKREWLEVLEDTKRALSEKRRREQEEAAAPRG 300
Query: 301 PPQVTSKATNPFEDDEEEEPAVPEVEEEKVDLSMEWIQELPEDLDVCIAQRDFEGAVDLL 360
PPQVTSKATNPFEDDEEEEPAVPEVEEEKVDLSMEWIQELPEDLDVCIAQRDFEGAVDLL
Sbjct: 301 PPQVTSKATNPFEDDEEEEPAVPEVEEEKVDLSMEWIQELPEDLDVCIAQRDFEGAVDLL 360
Query: 361 DKLNHYLEDKPSPPPVKELRAKVEERVRQLTEVLVFELSPDRSLRGGPKATRRAVSQLIR 420
DKLNHYLEDKPSPPPVKELRAKVEERVRQLTEVLVFELSPDRSLRGGPKATRRAVSQLIR
Sbjct: 361 DKLNHYLEDKPSPPPVKELRAKVEERVRQLTEVLVFELSPDRSLRGGPKATRRAVSQLIR 420
Query: 421 LGQCTKACELFLRNRAAAVHTAIRQLRIEGATLLYIHKLCHVFFTSLLETAREFEIDFAG 480
LGQCTKACELFLRNRAAAVHTAIRQLRIEGATLLYIHKLCHVFFTSLLETAREFEIDFAG
Sbjct: 421 LGQCTKACELFLRNRAAAVHTAIRQLRIEGATLLYIHKLCHVFFTSLLETAREFEIDFAG 480
Query: 481 TDSGCYSAFVVWARSAMGMFVDAFSKQVFDSKESLSTAAECVKVAKEHCQQLGDIGLDLT 540
TDSGCYSAFVVWARSAMGMFVDAFSKQVFDSKESLSTAAECVKVAKEHCQQLGDIGLDLT
Sbjct: 481 TDSGCYSAFVVWARSAMGMFVDAFSKQVFDSKESLSTAAECVKVAKEHCQQLGDIGLDLT 540
Query: 541 FIIHALLVKDIQGALHSYKEIIIEATKHRNSEEMWRRMNLMTPEALGKLKEEMKSCGVSN 600
FIIHALLVKDIQGALHSYKEIIIEATKHRNSEEMWRRMNLMTPEALGKLKEEMKSCGVSN
Sbjct: 541 FIIHALLVKDIQGALHSYKEIIIEATKHRNSEEMWRRMNLMTPEALGKLKEEMKSCGVSN 600
Query: 601 FEQYTGDDCWVNLSYTVVAFTKQTMGFLEEALKLYFPELHMVLLESLVEIILVAVQHVDY 660
FEQYTGDDCWVNLSYTVVAFTKQTMGFLEEALKLYFPELHMVLLESLVEIILVAVQHVDY
Sbjct: 601 FEQYTGDDCWVNLSYTVVAFTKQTMGFLEEALKLYFPELHMVLLESLVEIILVAVQHVDY 660
Query: 661 SLRCEQDPEKKAFIRQNASFLYETVLPVVEKRFEEGVGKPAKQLQDLRNASRLIRVNPES 720
SLRCEQDPEKKAFIRQNASFLYETVLPVVEKRFEEGVGKPAKQLQDLRNASRLIRVNPES
Sbjct: 661 SLRCEQDPEKKAFIRQNASFLYETVLPVVEKRFEEGVGKPAKQLQDLRNASRLIRVNPES 720
Query: 721 TTSVV 725
TTSVV
Sbjct: 721 TTSVV 725
>gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]
Length = 1780
Score = 42.7 bits (99), Expect = 0.001
Identities = 94/507 (18%), Positives = 208/507 (41%), Gaps = 91/507 (17%)
Query: 247 MKDMFKLLMFPESRIFQAENAKIKREWLEVLEDTKRALSEKRRR------EQEEAAAPRG 300
M++ FK ++ N I E +EV +D+K + +R+R +Q+E A +G
Sbjct: 750 MENTFKCNDKADTSSLIINNKLICNETVEVPKDSKSKICSERKRVNENELQQDEPPAKKG 809
Query: 301 PPQVTSKATNPFEDDEEEEPAVPEVEEEKVDLSMEWIQELPEDLDVCI------AQRDFE 354
V+S T + EE P + E+E+ +V +QE E L + + + E
Sbjct: 810 SIHVSSAITEDQKKSEEVRPNIAEIEDIRV------LQENNEGLRAFLLTIENELKNEKE 863
Query: 355 GAVDLLDKLNHYLEDKPSPPPVKELRAKVEERVRQLTEVLVFELSPDRSLRGGPKATRRA 414
+L ++ H+ ++ +K ++++ ++ + EL +S +
Sbjct: 864 EKAELNKQIVHFQQELSLSEKKNLTLSKEVQQIQSNYDIAIAELHVQKS------KNQEQ 917
Query: 415 VSQLIRLGQCTKACELFLRNRAAAV---HTAIRQLRIEGATLLYIHKLCHVFFTSLLETA 471
++++L + + N + + HT I +LR TL + ++ ++ +L + +
Sbjct: 918 EEKIMKLSNEIETATRSITNNVSQIKLMHTKIDELR----TLDSVSQISNIDLLNLRDLS 973
Query: 472 REFE--------IDFAGTDSGCYSAFVVWARSAMGMFVDAFSKQVFDSKESLSTAAECVK 523
E +D G D + V + Q + + S ++ E +
Sbjct: 974 NGSEEDNLPNTQLDLLGND------------YLVSKQVKEYRIQEPNRENSFHSSIEAI- 1020
Query: 524 VAKEHCQQLGDIGLDLTFIIHAL--LVKDIQGALHSYKE--IIIEATKHRNSEEMWRRMN 579
E C+++ + I L ++ +Q + YK+ ++ +H+N +++ +
Sbjct: 1021 --WEECKEIVKASSKKSHQIEELEQQIEKLQAEVKGYKDENNRLKEKEHKNQDDLLKEKE 1078
Query: 580 LMTPEALGKLKEEMKSCGVSNFEQYTGDDCWVNLSYTVVAFTKQTMGFLEEALKLYFPEL 639
+ + +LKEE++ V+ +++ V K+ + L + + Y ++
Sbjct: 1079 TL----IQQLKEELQEKNVT-----------LDVQIQHVVEGKRALSELTQGVTCYKAKI 1123
Query: 640 HMVLLESLVEIILVAVQHVDYSLRCEQD-PEKKAFI-------RQNASFLYETV-----L 686
LE+++E V H S + EQD EK++ I ++ L ++V L
Sbjct: 1124 KE--LETILETQKVECSH---SAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDL 1178
Query: 687 PVVEKRFEEGVGKPAKQLQDLRNASRL 713
V E + +E + + LQD+++ +L
Sbjct: 1179 NVKELKLKEEITQLTNNLQDMKHLLQL 1205
>gi|154240686 FYVE, RhoGEF and PH domain containing 6 [Homo sapiens]
Length = 1430
Score = 42.0 bits (97), Expect = 0.002
Identities = 34/115 (29%), Positives = 51/115 (44%), Gaps = 6/115 (5%)
Query: 174 HLLETPGQYLVYNGDLVEYDADHMAQLQRVHGFLMNDCLLVATWLPQRRGMYRYNALYSL 233
H + PG+ + G L++ M Q FL ND LL T P + GMY+ N + SL
Sbjct: 1081 HEIVQPGRVFLKEGILMKLSRKVM---QPRMFFLFNDALLYTT--PVQSGMYKLNNMLSL 1135
Query: 234 DGLAVVNVKDNPPMKDMFKLLMFPESRIFQAENAKIKREWLEVLEDTKRALSEKR 288
G+ V ++ K+ S I A +A + EWLE + ++KR
Sbjct: 1136 AGMKVRKPTQEAYQNEL-KIESVERSFILSASSATERDEWLEAISRAIEEYAKKR 1189
>gi|93204881 Rab interacting lysosomal protein [Homo sapiens]
Length = 401
Score = 39.7 bits (91), Expect = 0.010
Identities = 40/153 (26%), Positives = 62/153 (40%), Gaps = 23/153 (15%)
Query: 12 RLRRQLESGGFEARLYVKQLSQQSDGDRD-LQEHRQRIQALAEET---AQNLKRNVYQNY 67
RLRR+L +G E R ++QL + +D RD L+ H + ++ +ET + L+R + N
Sbjct: 97 RLRRELRAGPQEERALLRQLKEVTDRQRDELRAHNRDLRQRGQETEALQEQLQRLLLVN- 155
Query: 68 RQFIETAREISYLESEMYQLSHLLTEQKSSLESIPLTLLPAAAAAGAAAASGGEEGVGGA 127
+L H L ++ L + AA E G A
Sbjct: 156 -----------------AELRHKLAAMQTQLRAAQDRERERQQPGEAATPQAKERARGQA 198
Query: 128 GGRDHLRGQAGFFSTPG-GASRDGSGPGEEGKQ 159
G H GQ ++T G GA + P E +Q
Sbjct: 199 GRPGHQHGQEPEWATAGAGAPGNPEDPAEAAQQ 231
>gi|154759293 cysteine-rich hydrophobic domain 1 [Homo sapiens]
Length = 224
Score = 38.9 bits (89), Expect = 0.017
Identities = 22/58 (37%), Positives = 31/58 (53%), Gaps = 1/58 (1%)
Query: 284 LSEKRRREQEEAAAPRGPPQVTSKATNPFEDDEEEEPAVPEVEEEKVDLSMEWIQELP 341
+SE E+EEAA P +S + P +DDEE+E E EEE+ + E +E P
Sbjct: 14 ISELEEEEEEEAATSSSSPSSSSSVSGP-DDDEEDEEEEEEEEEEEEEEEEEEEEEAP 70
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 38.5 bits (88), Expect = 0.022
Identities = 78/379 (20%), Positives = 146/379 (38%), Gaps = 41/379 (10%)
Query: 41 LQEHRQRIQALAEETAQNLKRNVYQNYRQFIETAREISYLESEMYQLSHLLTEQKSSLES 100
LQ ++++Q + ++ ++ R+ E E L+ + HL E +SLE
Sbjct: 167 LQREKKKLQGILSQSQD-------KSLRRIAELREE---LQMDQQAKKHLQEEFDASLEE 216
Query: 101 IP--LTLLPAAAAAGAAAASGGEEGVGGAGGRDHLRGQAGFFSTPGGASRDGSGPGEEGK 158
+++L + G V L QA F+ DG E+G
Sbjct: 217 KDQYISVLQTQVSLLKQRLRNGPMNVDVLKPLPQLEPQAEVFTKEENPESDGEPVVEDGT 276
Query: 159 Q-RTLTTLLEKVEGCRHLLETPGQYLVYNGD-----------LVEYDADHMAQLQRVHGF 206
+TL TL ++V+ +LL+ + + + + L E + + +L+++
Sbjct: 277 SVKTLETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDL 336
Query: 207 LMNDCLLVATWLPQRRGMYRYNALYSLDGLAVVNVKDNPPMKDMFKLLMFPESRIFQAEN 266
M + + T L + + L G+ + K + M + L E I Q +
Sbjct: 337 HMAEKTKLITQLRDAKNLIEQ--LEQDKGMVIAETK-----RQMHETLEMKEEEIAQLRS 389
Query: 267 AKIKREWLEVLEDTKRALSEKRRREQEEAAAPRGPPQVTSKATNPF--EDDEEEEPAVPE 324
+IK+ + E+ + + R EE Q T +A E DE+ +
Sbjct: 390 -RIKQMTTQG-EELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKT 447
Query: 325 VEEEKVDLSMEWIQELPEDLDVCIAQRDFEGAVDLLDKLNHYLEDKPSPPPVKELRAKVE 384
EEE++ L E + E +DV ++ E + L KL+ +K +EL K++
Sbjct: 448 SEEERISLQQELSRVKQEVVDV--MKKSSEEQIAKLQKLH----EKELARKEQELTKKLQ 501
Query: 385 ERVRQLTEVLVFELSPDRS 403
R R+ E + L +S
Sbjct: 502 TREREFQEQMKVALEKSQS 520
>gi|223671856 coiled-coil domain containing 85C [Homo sapiens]
Length = 419
Score = 37.7 bits (86), Expect = 0.038
Identities = 33/114 (28%), Positives = 48/114 (42%), Gaps = 8/114 (7%)
Query: 41 LQEHRQRIQALAEETAQNLKRNVYQNYRQFIETAREISYLESEMYQLSHLLTEQKSSLES 100
L + RQ+ + LA E + + + + + +++ LE+ LL E E
Sbjct: 91 LDDDRQKGRKLAREWQRFGRHAAGAVWHEVARSQQKLRELEARQ---EALLRENLELKEL 147
Query: 101 IPLTLLPAAAAAGAAAASGGEEGVGGAGGRDHLRGQAGFF-----STPGGASRD 149
+ L AA A AASGG G GGAG R + QA PG +RD
Sbjct: 148 VLLLDEERAALAATGAASGGGGGGGGAGSRSSIDSQASLSGPLSGGAPGAGARD 201
>gi|197313672 carnitine deficiency-associated gene expressed in
ventricle 3 isoform a [Homo sapiens]
Length = 213
Score = 37.7 bits (86), Expect = 0.038
Identities = 25/57 (43%), Positives = 30/57 (52%), Gaps = 8/57 (14%)
Query: 108 AAAAAGAAAASGGEEGVGGAGGRDHLRGQAGFFSTPGG---ASRDGSGPGEEGKQRT 161
AA+AAGAA ++GG G GA G G AG + PG AS +GPG K T
Sbjct: 28 AASAAGAAGSAGGSSGAAGAAG-----GGAGAGTRPGDGGTASAGAAGPGAATKAVT 79
>gi|8923710 carnitine deficiency-associated gene expressed in
ventricle 3 isoform b [Homo sapiens]
Length = 258
Score = 37.7 bits (86), Expect = 0.038
Identities = 25/57 (43%), Positives = 30/57 (52%), Gaps = 8/57 (14%)
Query: 108 AAAAAGAAAASGGEEGVGGAGGRDHLRGQAGFFSTPGG---ASRDGSGPGEEGKQRT 161
AA+AAGAA ++GG G GA G G AG + PG AS +GPG K T
Sbjct: 28 AASAAGAAGSAGGSSGAAGAAG-----GGAGAGTRPGDGGTASAGAAGPGAATKAVT 79
>gi|110347449 POU domain, class 4, transcription factor 1 [Homo
sapiens]
Length = 419
Score = 37.7 bits (86), Expect = 0.038
Identities = 24/61 (39%), Positives = 27/61 (44%), Gaps = 14/61 (22%)
Query: 98 LESIPLTLLPAAAAAGAAAASGG-EEGVGGAGGRDHLRGQAGFFSTPGGASRDGSGPGEE 156
+ S L L+ A AGAAA GG +G GG GG PGG G GPG
Sbjct: 120 ISSPSLALMAGAGGAGAAAGGGGAHDGPGGGGG-------------PGGGGGPGGGPGGG 166
Query: 157 G 157
G
Sbjct: 167 G 167
>gi|22547197 zinc finger protein of the cerebellum 2 [Homo sapiens]
Length = 532
Score = 37.4 bits (85), Expect = 0.049
Identities = 28/67 (41%), Positives = 30/67 (44%), Gaps = 10/67 (14%)
Query: 93 EQKSSLESIPLTLLPAAAAAGAAAA-----SGGEEGVGGAGGRDHLRGQAGFFSTPGGAS 147
E +SS P AAAAA AAAA GG G GGAGG G G + GG
Sbjct: 446 EPQSSSNLSPAAAAAAAAAAAAAAAVSAVHRGGGSGSGGAGG-----GSGGGSGSGGGGG 500
Query: 148 RDGSGPG 154
G G G
Sbjct: 501 GAGGGGG 507
>gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens]
Length = 474
Score = 37.0 bits (84), Expect = 0.065
Identities = 23/65 (35%), Positives = 32/65 (49%), Gaps = 2/65 (3%)
Query: 109 AAAAGAAAASGGEEG--VGGAGGRDHLRGQAGFFSTPGGASRDGSGPGEEGKQRTLTTLL 166
++++ AA++ GE+G VGG+GG H G G S GG SG G K +
Sbjct: 141 SSSSAAASSKPGEKGDKVGGSGGGGHGGGGGGGSSNAGGGGGGASGGGANSKPAQKKSCG 200
Query: 167 EKVEG 171
KV G
Sbjct: 201 SKVAG 205
>gi|4507693 tuberous sclerosis 1 protein isoform 1 [Homo sapiens]
Length = 1164
Score = 36.6 bits (83), Expect = 0.084
Identities = 26/91 (28%), Positives = 44/91 (48%), Gaps = 3/91 (3%)
Query: 13 LRRQLESGGFEARLYVKQLSQQSDGDRDLQEHRQRIQALAEETAQNLKRNVYQNYRQFIE 72
L RQL G LY++QL + D + + ++A + + + +V Q ++
Sbjct: 848 LNRQLLVLGEVNELYLEQLQNKHS---DTTKEVEMMKAAYRKELEKNRSHVLQQTQRLDT 904
Query: 73 TAREISYLESEMYQLSHLLTEQKSSLESIPL 103
+ + I LES + + HLL EQK LE + L
Sbjct: 905 SQKRILELESHLAKKDHLLLEQKKYLEDVKL 935
>gi|241666464 tuberous sclerosis 1 protein isoform 4 [Homo sapiens]
Length = 1113
Score = 36.6 bits (83), Expect = 0.084
Identities = 26/91 (28%), Positives = 44/91 (48%), Gaps = 3/91 (3%)
Query: 13 LRRQLESGGFEARLYVKQLSQQSDGDRDLQEHRQRIQALAEETAQNLKRNVYQNYRQFIE 72
L RQL G LY++QL + D + + ++A + + + +V Q ++
Sbjct: 797 LNRQLLVLGEVNELYLEQLQNKHS---DTTKEVEMMKAAYRKELEKNRSHVLQQTQRLDT 853
Query: 73 TAREISYLESEMYQLSHLLTEQKSSLESIPL 103
+ + I LES + + HLL EQK LE + L
Sbjct: 854 SQKRILELESHLAKKDHLLLEQKKYLEDVKL 884
>gi|241666462 tuberous sclerosis 1 protein isoform 3 [Homo sapiens]
Length = 1163
Score = 36.6 bits (83), Expect = 0.084
Identities = 26/91 (28%), Positives = 44/91 (48%), Gaps = 3/91 (3%)
Query: 13 LRRQLESGGFEARLYVKQLSQQSDGDRDLQEHRQRIQALAEETAQNLKRNVYQNYRQFIE 72
L RQL G LY++QL + D + + ++A + + + +V Q ++
Sbjct: 847 LNRQLLVLGEVNELYLEQLQNKHS---DTTKEVEMMKAAYRKELEKNRSHVLQQTQRLDT 903
Query: 73 TAREISYLESEMYQLSHLLTEQKSSLESIPL 103
+ + I LES + + HLL EQK LE + L
Sbjct: 904 SQKRILELESHLAKKDHLLLEQKKYLEDVKL 934
>gi|33620755 YEATS domain containing 2 [Homo sapiens]
Length = 1422
Score = 36.2 bits (82), Expect = 0.11
Identities = 20/61 (32%), Positives = 29/61 (47%)
Query: 108 AAAAAGAAAASGGEEGVGGAGGRDHLRGQAGFFSTPGGASRDGSGPGEEGKQRTLTTLLE 167
+AA+ G+ A GG G GG G G T GG ++ +GPG + T T+ +
Sbjct: 795 SAASGGSGAGGGGGGGGGGGSGSGGGGSTGGGGGTAGGGTQSTAGPGGISQHLTYTSYIL 854
Query: 168 K 168
K
Sbjct: 855 K 855
>gi|44890059 involucrin [Homo sapiens]
Length = 585
Score = 35.8 bits (81), Expect = 0.14
Identities = 21/76 (27%), Positives = 42/76 (55%), Gaps = 3/76 (3%)
Query: 26 LYVKQLSQQSDGDRDLQEHRQRIQALAEETAQNLKRNVYQNYRQFIETAREISYLESEMY 85
L +KQL +Q + L+E +++ L ++ Q +++ Q Q + R++ +LE ++
Sbjct: 371 LQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQ--LKHLVQQEGQLEQQERQVEHLEQQVG 428
Query: 86 QLSHLLTEQKSSLESI 101
QL H L EQ+ L+ +
Sbjct: 429 QLKH-LEEQEGQLKHL 443
Score = 32.7 bits (73), Expect = 1.2
Identities = 66/329 (20%), Positives = 124/329 (37%), Gaps = 58/329 (17%)
Query: 30 QLSQQSDGDRDLQEHRQRIQALAEETAQNLKRNVYQNYRQFI--ETAREISYLESEMYQL 87
+L QQ +G +L E ++ L+E+ LK +Q + + E ++ YLE + QL
Sbjct: 234 ELPQQQEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQL 293
Query: 88 SHLLTEQKSSLESIPLTLL------------PAAAAAGAAAASGGEEGVG-------GAG 128
HL +Q+ +P + P EE G G
Sbjct: 294 KHL--DQQEKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEG 351
Query: 129 GRDHLRGQAGFFSTPGGASRDGSGPGEEGKQRTLTTLLEKVEG-CRHLLETPGQ--YLVY 185
+HL Q G P + + KQ+ LE+ EG +HL++ GQ +LV
Sbjct: 352 QLEHLEHQEGQLGLP---EQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQ 408
Query: 186 NGDLVEYDADHMAQLQRVHGFLMNDCLLVATWLPQRRGMYRYNALYSLDGLAVVNVKDNP 245
+E + L++ G L + L ++ G ++
Sbjct: 409 QEGQLEQQERQVEHLEQQVGQLKH--------LEEQEGQLKH------------------ 442
Query: 246 PMKDMFKLLMFPESRIFQAENAKIKREWLEVLEDTKRALS--EKRRREQEEAAAPRGPPQ 303
++ L PE ++ Q +N + + + LE+ E + + EK+ + E G P+
Sbjct: 443 -LEQQQGQLEVPEQQVGQPKNLEQEEKQLELPEQQEGQVKHLEKQEAQLELPEQQVGQPK 501
Query: 304 VTSKATNPFEDDEEEEPAVPEVEEEKVDL 332
+ E E+++ + +E+++ L
Sbjct: 502 HLEQQEKHLEHPEQQDGQLKHLEQQEGQL 530
>gi|210032790 hypothetical protein LOC27146 [Homo sapiens]
Length = 1060
Score = 35.8 bits (81), Expect = 0.14
Identities = 41/159 (25%), Positives = 65/159 (40%), Gaps = 19/159 (11%)
Query: 4 AMSDSGASRLRRQLESGGF-EARLYVKQLSQQSDGDRDLQE--HRQRIQALAEETAQNLK 60
A ++ R R LE E + ++L ++S +Q HR +QAL E+ Q L+
Sbjct: 657 AQLEASHQRALRMLEKARHQELKATEERLKKESSHSLQIQHQTHRLELQALEEKARQELQ 716
Query: 61 RNVYQNYRQFIETAREISYLESEMYQLSHLLTEQKSSLESIPLTLLPAAAAAGAAAASGG 120
+ R + A + L E+ + + + LE++ L A G AS
Sbjct: 717 E---ERERMQAQQALLLESLRQELSEQQAACSGHQKDLEALQAEL----RALGRQQASSQ 769
Query: 121 EEGVGGAGGRDHL-----RGQAGFFSTPGGASRDGSGPG 154
G +DH+ RG G +P GA+ GSG G
Sbjct: 770 CPG----DSKDHIIATEERGGPGQAGSPPGAAGQGSGEG 804
>gi|13775236 scratch [Homo sapiens]
Length = 348
Score = 35.8 bits (81), Expect = 0.14
Identities = 24/68 (35%), Positives = 32/68 (47%), Gaps = 1/68 (1%)
Query: 91 LTEQKSSLESIPLTLLPAAAAAGAAAASGGEEGVGGAGGRDHLRGQAGFFSTPGGASRDG 150
+T+ +S ++ A + A AAA G G GGAGGR G G T GA +
Sbjct: 119 ITDGRSRRKASNAGSAAAPSTASAAAPDGDAGGGGGAGGRSLGSGPGGRGGTRAGAGTEA 178
Query: 151 -SGPGEEG 157
+GPG G
Sbjct: 179 RAGPGAAG 186
>gi|239753428 PREDICTED: hypothetical protein [Homo sapiens]
Length = 117
Score = 35.4 bits (80), Expect = 0.19
Identities = 25/68 (36%), Positives = 30/68 (44%), Gaps = 5/68 (7%)
Query: 105 LLPAAAAAGAAAASGGEEGVGGAGGRDHLR----GQAGFFSTPGGASRDGSGPGEEGKQR 160
L P A + G E G GG GG H R GQAG + G R+GSG GE
Sbjct: 29 LPPRCQVARGSQEEGRERGTGG-GGWSHRRVLSLGQAGRRAAGWGGGREGSGSGETPAAS 87
Query: 161 TLTTLLEK 168
+ LL +
Sbjct: 88 AASLLLRQ 95
>gi|239747997 PREDICTED: hypothetical protein [Homo sapiens]
Length = 117
Score = 35.4 bits (80), Expect = 0.19
Identities = 25/68 (36%), Positives = 30/68 (44%), Gaps = 5/68 (7%)
Query: 105 LLPAAAAAGAAAASGGEEGVGGAGGRDHLR----GQAGFFSTPGGASRDGSGPGEEGKQR 160
L P A + G E G GG GG H R GQAG + G R+GSG GE
Sbjct: 29 LPPRCQVARGSQEEGRERGTGG-GGWSHRRVLSLGQAGRRAAGWGGGREGSGSGETPAAS 87
Query: 161 TLTTLLEK 168
+ LL +
Sbjct: 88 AASLLLRQ 95
>gi|22035606 mitogen-activated protein kinase kinase kinase kinase 4
isoform 3 [Homo sapiens]
Length = 1212
Score = 35.4 bits (80), Expect = 0.19
Identities = 33/123 (26%), Positives = 58/123 (47%), Gaps = 10/123 (8%)
Query: 270 KREWLEVLEDTKRALSEKRRREQE----EAAAPRGPPQVTSKATNPFE--DDEEEEPAVP 323
+++ +E ++ +R L E++RRE+E + R Q + E EEEE
Sbjct: 395 RQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRA 454
Query: 324 EVEEEKVDLSMEWIQELPED----LDVCIAQRDFEGAVDLLDKLNHYLEDKPSPPPVKEL 379
E E+ +V+ E+I+ E+ L+V Q E A+ L D + + PPP ++
Sbjct: 455 EEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQAMLLHDHRRPHPQHSQQPPPPQQE 514
Query: 380 RAK 382
R+K
Sbjct: 515 RSK 517
>gi|22035602 mitogen-activated protein kinase kinase kinase kinase 4
isoform 1 [Homo sapiens]
Length = 1166
Score = 35.4 bits (80), Expect = 0.19
Identities = 33/123 (26%), Positives = 58/123 (47%), Gaps = 10/123 (8%)
Query: 270 KREWLEVLEDTKRALSEKRRREQE----EAAAPRGPPQVTSKATNPFE--DDEEEEPAVP 323
+++ +E ++ +R L E++RRE+E + R Q + E EEEE
Sbjct: 395 RQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRA 454
Query: 324 EVEEEKVDLSMEWIQELPED----LDVCIAQRDFEGAVDLLDKLNHYLEDKPSPPPVKEL 379
E E+ +V+ E+I+ E+ L+V Q E A+ L D + + PPP ++
Sbjct: 455 EEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQAMLLHDHRRPHPQHSQQPPPPQQE 514
Query: 380 RAK 382
R+K
Sbjct: 515 RSK 517
>gi|51317384 GLE1 RNA export mediator homolog isoform 1 [Homo
sapiens]
Length = 698
Score = 35.0 bits (79), Expect = 0.25
Identities = 35/162 (21%), Positives = 70/162 (43%), Gaps = 25/162 (15%)
Query: 263 QAENAKIKREWLEVL----EDTKRALSEKRRREQEEAAAPRGPPQVTSKATNPFEDDEEE 318
QAE + RE ++L ++ RA +KRR+++EEA Q+ + +
Sbjct: 308 QAEAERALREMRDLLMNLGQEITRACEDKRRQDEEEAQVKLQEAQMQQ------GPEAHK 361
Query: 319 EPAVP----------EVEEEKVDLSMEWIQELPEDLDVCIAQRDFEGAVDLLDKLNHYLE 368
EP P +++ + D++M+W Q+L + C+ FEG + D ++
Sbjct: 362 EPPAPSQGPGGKQNEDLQVKVQDITMQWYQQLQDASMQCVL--TFEGLTNSKDSQAKKIK 419
Query: 369 ---DKPSPPPVKELRAKVEERVRQLTEVLVFELSPDRSLRGG 407
K + PV ++ +++++ + + LS GG
Sbjct: 420 MDLQKAATIPVSQISTIAGSKLKEIFDKIHSLLSGKPVQSGG 461
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 35.0 bits (79), Expect = 0.25
Identities = 23/74 (31%), Positives = 36/74 (48%), Gaps = 3/74 (4%)
Query: 258 ESRIFQAENAKIKREWLEVLEDTKRALSEKRRR---EQEEAAAPRGPPQVTSKATNPFED 314
+S + +A A + + + E+ K A EK E+EE AA + P + T+ E
Sbjct: 466 KSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEG 525
Query: 315 DEEEEPAVPEVEEE 328
++EEE E EEE
Sbjct: 526 EKEEEEGQEEEEEE 539
Score = 30.0 bits (66), Expect = 7.9
Identities = 26/89 (29%), Positives = 45/89 (50%), Gaps = 5/89 (5%)
Query: 257 PESRIFQAENAKIKREWLEVLEDTKRALSEKRRREQEEAAAPRGP-PQVTSKA-TNPFED 314
P+S + + + + + +E E K +S+ E+ ++ P+ P + SKA E
Sbjct: 644 PKSPVEEKGKSPVPKSPVE--EKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQ 701
Query: 315 DEEEEPAVPEV-EEEKVDLSMEWIQELPE 342
EEEE V E +EEKV+ E +++PE
Sbjct: 702 KEEEEKEVKEAPKEEKVEKKEEKPKDVPE 730
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 35.0 bits (79), Expect = 0.25
Identities = 23/74 (31%), Positives = 36/74 (48%), Gaps = 3/74 (4%)
Query: 258 ESRIFQAENAKIKREWLEVLEDTKRALSEKRRR---EQEEAAAPRGPPQVTSKATNPFED 314
+S + +A A + + + E+ K A EK E+EE AA + P + T+ E
Sbjct: 90 KSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEG 149
Query: 315 DEEEEPAVPEVEEE 328
++EEE E EEE
Sbjct: 150 EKEEEEGQEEEEEE 163
Score = 30.0 bits (66), Expect = 7.9
Identities = 26/89 (29%), Positives = 45/89 (50%), Gaps = 5/89 (5%)
Query: 257 PESRIFQAENAKIKREWLEVLEDTKRALSEKRRREQEEAAAPRGP-PQVTSKA-TNPFED 314
P+S + + + + + +E E K +S+ E+ ++ P+ P + SKA E
Sbjct: 268 PKSPVEEKGKSPVPKSPVE--EKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQ 325
Query: 315 DEEEEPAVPEV-EEEKVDLSMEWIQELPE 342
EEEE V E +EEKV+ E +++PE
Sbjct: 326 KEEEEKEVKEAPKEEKVEKKEEKPKDVPE 354
>gi|156104874 envoplakin [Homo sapiens]
Length = 2033
Score = 35.0 bits (79), Expect = 0.25
Identities = 34/136 (25%), Positives = 55/136 (40%), Gaps = 30/136 (22%)
Query: 259 SRIFQAENAKIKREWLEVLEDTKRALSEKRRREQEEAAAPRGPPQVTSKATNPFEDDEEE 318
S + + + ++++W +++ D E +Q E + ++ N EDD E
Sbjct: 240 SALAEQQRRILQQDWSDLMADPAGVRREYEHFKQHELLSQE-------QSVNQLEDDGER 292
Query: 319 -----EPAVPEVEEEKVDLSMEWIQELPEDLDVCIAQ----------RDFEGAVD----L 359
PAV ++ + L MEW L++CI Q R F+ D
Sbjct: 293 MVELRHPAVGPIQAHQEALKMEW----QNFLNLCICQETQLQHVEDYRRFQEEADSVSQT 348
Query: 360 LDKLNHYLEDKPSPPP 375
L KLN L+ K SP P
Sbjct: 349 LAKLNSNLDAKYSPAP 364
>gi|4557627 GLE1 RNA export mediator homolog isoform 2 [Homo
sapiens]
Length = 659
Score = 35.0 bits (79), Expect = 0.25
Identities = 35/162 (21%), Positives = 70/162 (43%), Gaps = 25/162 (15%)
Query: 263 QAENAKIKREWLEVL----EDTKRALSEKRRREQEEAAAPRGPPQVTSKATNPFEDDEEE 318
QAE + RE ++L ++ RA +KRR+++EEA Q+ + +
Sbjct: 308 QAEAERALREMRDLLMNLGQEITRACEDKRRQDEEEAQVKLQEAQMQQ------GPEAHK 361
Query: 319 EPAVP----------EVEEEKVDLSMEWIQELPEDLDVCIAQRDFEGAVDLLDKLNHYLE 368
EP P +++ + D++M+W Q+L + C+ FEG + D ++
Sbjct: 362 EPPAPSQGPGGKQNEDLQVKVQDITMQWYQQLQDASMQCVL--TFEGLTNSKDSQAKKIK 419
Query: 369 ---DKPSPPPVKELRAKVEERVRQLTEVLVFELSPDRSLRGG 407
K + PV ++ +++++ + + LS GG
Sbjct: 420 MDLQKAATIPVSQISTIAGSKLKEIFDKIHSLLSGKPVQSGG 461
>gi|194018511 keratin 77 [Homo sapiens]
Length = 578
Score = 34.7 bits (78), Expect = 0.32
Identities = 43/163 (26%), Positives = 64/163 (39%), Gaps = 23/163 (14%)
Query: 37 GDRDLQEHRQRIQALAEETAQNLKRNVYQNYRQF-----------IETAREISYLESEMY 85
G++ LQ+ Q++Q L EE Q K + + R + +E A LE E
Sbjct: 417 GEQALQDAWQKLQDL-EEALQQSKEELARLLRDYQAMLGVKLSLDVEIATYRQLLEGEES 475
Query: 86 QLSHLLTEQKS-SLESIPLTLLPAAAAAGAAAASG--GEEGVGGAGGRDHLRGQA----- 137
++S L S S+++ +++ A G+ + G G G G GGR + G A
Sbjct: 476 RMSGELQSHVSISVQNSQVSVNGGAGGGGSYGSGGYGGGSGGGYGGGRSYRGGGARGRSG 535
Query: 138 ---GFFSTPGGASRDGSGPGEEGKQRTLTTLLEKVEGCRHLLE 177
G GG S GSG G R R +LE
Sbjct: 536 GGYGSGCGGGGGSYGGSGRSGRGSSRVQIIQTSTNTSHRRILE 578
>gi|32967601 ankyrin 3 isoform 1 [Homo sapiens]
Length = 4377
Score = 34.7 bits (78), Expect = 0.32
Identities = 33/149 (22%), Positives = 61/149 (40%), Gaps = 24/149 (16%)
Query: 258 ESRIFQAENAKIKREWLEVLEDTKRALSEKRRREQEEAAAPRGPPQVTSKATNPFEDDEE 317
E I Q KI + + +++T+ R +Q++ +P+G P+ + F D
Sbjct: 3106 EKEIQQGGVKKIISQECKTVQETRGTFYTTR--QQKQPPSPQGSPEDDTLEQVSFLDSSG 3163
Query: 318 EEPAVPEVEEEKVDLSMEWIQELPEDLDVCIAQRDFEGAVDLLDKLNHYLEDKPSPPPVK 377
+ P PE + ++S E+ + P D L Y+ KPSP P
Sbjct: 3164 KSPLTPETPSSE-EVSYEFTSKTP-------------------DSLIAYIPGKPSPIPEV 3203
Query: 378 ELRAKVEERVR--QLTEVLVFELSPDRSL 404
++ EE+ + L + V E + +R +
Sbjct: 3204 SEESEEEEQAKSTSLKQTTVEETAVEREM 3232
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.133 0.383
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,643,626
Number of Sequences: 37866
Number of extensions: 1317806
Number of successful extensions: 11448
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 65
Number of HSP's successfully gapped in prelim test: 202
Number of HSP's that attempted gapping in prelim test: 9937
Number of HSP's gapped (non-prelim): 1504
length of query: 725
length of database: 18,247,518
effective HSP length: 110
effective length of query: 615
effective length of database: 14,082,258
effective search space: 8660588670
effective search space used: 8660588670
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.