BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|44662836 breast cancer anti-estrogen resistance 1 [Homo sapiens] (870 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|44662836 breast cancer anti-estrogen resistance 1 [Homo sapiens] 1769 0.0 gi|5453680 neural precursor cell expressed, developmentally down... 516 e-146 gi|215422375 neural precursor cell expressed, developmentally do... 514 e-145 gi|239745060 PREDICTED: similar to breast cancer anti-estrogen r... 443 e-124 gi|239750776 PREDICTED: similar to breast cancer anti-estrogen r... 442 e-124 gi|239756225 PREDICTED: similar to breast cancer anti-estrogen r... 441 e-123 gi|239745044 PREDICTED: similar to breast cancer anti-estrogen r... 441 e-123 gi|55769585 HEF-like protein [Homo sapiens] 199 9e-51 gi|5031681 embryonal Fyn-associated substrate isoform 1 [Homo sa... 148 2e-35 gi|14589876 embryonal Fyn-associated substrate isoform 2 [Homo s... 140 4e-33 gi|78486553 neural precursor cell expressed, developmentally dow... 130 4e-30 gi|47132519 Ras association and pleckstrin homology domains 1 is... 74 8e-13 gi|242117953 SH3 domain-containing protein C1orf113 isoform 1 [H... 72 2e-12 gi|242117948 SH3 domain-containing protein C1orf113 isoform 2 [H... 72 2e-12 gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 72 2e-12 gi|182765466 FCH and double SH3 domains 2 [Homo sapiens] 70 1e-11 gi|163965366 nascent polypeptide-associated complex alpha subuni... 70 1e-11 gi|149158690 HLA-B associated transcript-2 [Homo sapiens] 67 5e-11 gi|110349719 titin isoform N2-A [Homo sapiens] 67 7e-11 gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [... 67 7e-11 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 64 5e-10 gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 64 6e-10 gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 64 6e-10 gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 64 6e-10 gi|116284392 mucin 2 precursor [Homo sapiens] 64 8e-10 gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 64 8e-10 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 63 1e-09 gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom... 62 2e-09 gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom... 62 2e-09 gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap... 62 2e-09 >gi|44662836 breast cancer anti-estrogen resistance 1 [Homo sapiens] Length = 870 Score = 1769 bits (4581), Expect = 0.0 Identities = 870/870 (100%), Positives = 870/870 (100%) Query: 1 MNHLNVLAKALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNRL 60 MNHLNVLAKALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNRL Sbjct: 1 MNHLNVLAKALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNRL 60 Query: 61 KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPAPPASQYTPMLPNTYQPQPDSVYLVPTP 120 KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPAPPASQYTPMLPNTYQPQPDSVYLVPTP Sbjct: 61 KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPAPPASQYTPMLPNTYQPQPDSVYLVPTP 120 Query: 121 SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVPPGPGGPAQDIYQ 180 SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVPPGPGGPAQDIYQ Sbjct: 121 SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVPPGPGGPAQDIYQ 180 Query: 181 VPPSAGMGHDIYQVPPSMDTRSWEGTKPPAKVVVPTRVGQGYVYEAAQPEQDEYDIPRHL 240 VPPSAGMGHDIYQVPPSMDTRSWEGTKPPAKVVVPTRVGQGYVYEAAQPEQDEYDIPRHL Sbjct: 181 VPPSAGMGHDIYQVPPSMDTRSWEGTKPPAKVVVPTRVGQGYVYEAAQPEQDEYDIPRHL 240 Query: 241 LAPGPQDIYDVPPVRGLLPSQYGQEVYDTPPMAVKGPNGRDPLLEVYDVPPSVEKGLPPS 300 LAPGPQDIYDVPPVRGLLPSQYGQEVYDTPPMAVKGPNGRDPLLEVYDVPPSVEKGLPPS Sbjct: 241 LAPGPQDIYDVPPVRGLLPSQYGQEVYDTPPMAVKGPNGRDPLLEVYDVPPSVEKGLPPS 300 Query: 301 NHHAVYDVPPSVSKDVPDGPLLREETYDVPPAFAKAKPFDPARTPLVLAAPPPDSPPAED 360 NHHAVYDVPPSVSKDVPDGPLLREETYDVPPAFAKAKPFDPARTPLVLAAPPPDSPPAED Sbjct: 301 NHHAVYDVPPSVSKDVPDGPLLREETYDVPPAFAKAKPFDPARTPLVLAAPPPDSPPAED 360 Query: 361 VYDVPPPAPDLYDVPPGLRRPGPGTLYDVPRERVLPPEVADGGVVDSGVYAVPPPAEREA 420 VYDVPPPAPDLYDVPPGLRRPGPGTLYDVPRERVLPPEVADGGVVDSGVYAVPPPAEREA Sbjct: 361 VYDVPPPAPDLYDVPPGLRRPGPGTLYDVPRERVLPPEVADGGVVDSGVYAVPPPAEREA 420 Query: 421 PAEGKRLSASSTGSTRSSQSASSLEVAGPGREPLELEVAVEALARLQQGVSATVAHLLDL 480 PAEGKRLSASSTGSTRSSQSASSLEVAGPGREPLELEVAVEALARLQQGVSATVAHLLDL Sbjct: 421 PAEGKRLSASSTGSTRSSQSASSLEVAGPGREPLELEVAVEALARLQQGVSATVAHLLDL 480 Query: 481 AGSAGATGSWRSPSEPQEPLVQDLQAAVAAVQSAVHELLEFARSAVGNAAHTSDRALHAK 540 AGSAGATGSWRSPSEPQEPLVQDLQAAVAAVQSAVHELLEFARSAVGNAAHTSDRALHAK Sbjct: 481 AGSAGATGSWRSPSEPQEPLVQDLQAAVAAVQSAVHELLEFARSAVGNAAHTSDRALHAK 540 Query: 541 LSRQLQKMEDVHQTLVAHGQALDAGRGGSGATLEDLDRLVACSRAVPEDAKQLASFLHGN 600 LSRQLQKMEDVHQTLVAHGQALDAGRGGSGATLEDLDRLVACSRAVPEDAKQLASFLHGN Sbjct: 541 LSRQLQKMEDVHQTLVAHGQALDAGRGGSGATLEDLDRLVACSRAVPEDAKQLASFLHGN 600 Query: 601 ASLLFRRTKATAPGPEGGGTLHPNPTDKTSSIQSRPLPSPPKFTSQDSPDGQYENSEGGW 660 ASLLFRRTKATAPGPEGGGTLHPNPTDKTSSIQSRPLPSPPKFTSQDSPDGQYENSEGGW Sbjct: 601 ASLLFRRTKATAPGPEGGGTLHPNPTDKTSSIQSRPLPSPPKFTSQDSPDGQYENSEGGW 660 Query: 661 MEDYDYVHLQGKEEFEKTQKELLEKGSITRQGKSQLELQQLKQFERLEQEVSRPIDHDLA 720 MEDYDYVHLQGKEEFEKTQKELLEKGSITRQGKSQLELQQLKQFERLEQEVSRPIDHDLA Sbjct: 661 MEDYDYVHLQGKEEFEKTQKELLEKGSITRQGKSQLELQQLKQFERLEQEVSRPIDHDLA 720 Query: 721 NWTPAQPLAPGRTGGLGPSDRQLLLFYLEQCEANLTTLTNAVDAFFTAVATNQPPKIFVA 780 NWTPAQPLAPGRTGGLGPSDRQLLLFYLEQCEANLTTLTNAVDAFFTAVATNQPPKIFVA Sbjct: 721 NWTPAQPLAPGRTGGLGPSDRQLLLFYLEQCEANLTTLTNAVDAFFTAVATNQPPKIFVA 780 Query: 781 HSKFVILSAHKLVFIGDTLSRQAKAADVRSQVTHYSNLLCDLLRGIVATTKAAALQYPSP 840 HSKFVILSAHKLVFIGDTLSRQAKAADVRSQVTHYSNLLCDLLRGIVATTKAAALQYPSP Sbjct: 781 HSKFVILSAHKLVFIGDTLSRQAKAADVRSQVTHYSNLLCDLLRGIVATTKAAALQYPSP 840 Query: 841 SAAQDMVERVKELGHSTQQFRRVLGQLAAA 870 SAAQDMVERVKELGHSTQQFRRVLGQLAAA Sbjct: 841 SAAQDMVERVKELGHSTQQFRRVLGQLAAA 870 >gi|5453680 neural precursor cell expressed, developmentally down-regulated 9 isoform 1 [Homo sapiens] Length = 834 Score = 516 bits (1328), Expect = e-146 Identities = 372/940 (39%), Positives = 491/940 (52%), Gaps = 180/940 (19%) Query: 1 MNHLNVLAKALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNRL 60 M + N++A+ALYDNV E +EL+FRKGDI+TV+EQ+T GL+GWWLCSLHGRQGIVPGNR+ Sbjct: 1 MKYKNLMARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRV 60 Query: 61 KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPAPPASQYTPMLPNTYQPQPDSVYLVPTP 120 K+L+G P ++ QP GL + T+ Sbjct: 61 KLLIG--------PMQETASSHEQPASGL-------------MQQTF------------- 86 Query: 121 SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVPPGPGGPAQDIYQ 180 QQ LYQVP P +P +YQVPP Q IYQ Sbjct: 87 --GQQKLYQVPNPQA-----------------------APRDTIYQVPPSYQN--QGIYQ 119 Query: 181 VPPSAG-MGHDIYQVPPSMDTRSWEGTKPP---AKVVVPTRVGQGYVYEAAQPEQDEYDI 236 VP G ++YQVPPS+ RS GT P KV+ P R G GYVYE Q Sbjct: 120 VPTGHGTQEQEVYQVPPSVQ-RSIGGTSGPHVGKKVITPVRTGHGYVYEYPSRYQ----- 173 Query: 237 PRHLLAPGPQDIYDVPPVRGLLPSQYGQEVYDTPPMAVKGPNGRDPLLE-----VYDVPP 291 +D+YD+PP S Q VYD PP + KGP P+ E VYD+PP Sbjct: 174 ---------KDVYDIPP------SHTTQGVYDIPPSSAKGPVFSVPVGEIKPQGVYDIPP 218 Query: 292 SVEKGLPPSNHHAVYDVPPSVSKDVPDGPLLREETYDVPPAFAKAKPFDPARTPLVLAAP 351 + KG VY +PPS +D LRE+ YD PP +A D R V P Sbjct: 219 T--KG--------VYAIPPSACRDEAG---LREKDYDFPPPMRQAGRPD-LRPEGVYDIP 264 Query: 352 PPDSPPA-EDVY-----DVP----PPAPDLYDVPPGLRRPGPGT-------LYDVPR--E 392 P + PA +D++ D+P P A + P P G YDVPR + Sbjct: 265 PTCTKPAGKDLHVKYNCDIPGAAEPVARRHQSLSPNHPPPQLGQSVGSQNDAYDVPRGVQ 324 Query: 393 RVLPP----EVADGGVVDSGVYAVP---PP---AEREAPAEGKRLSASSTGSTRSSQSAS 442 + PP E A+ D GVY VP PP R+ RLS SSTGSTRS+ S S Sbjct: 325 FLEPPAETSEKANPQERD-GVYDVPLHNPPDAKGSRDLVDGINRLSFSSTGSTRSNMSTS 383 Query: 443 SLEV------AGPGREP---LELEVAVEALARLQQGVSATVAHLLDLAGSAGATGSWRSP 493 S A P ++ L+ + A+E L RLQQ + V+ L+ L T WR Sbjct: 384 STSSKESSLSASPAQDKRLFLDPDTAIERLQRLQQALEMGVSSLMALV-----TTDWRCY 438 Query: 494 SEPQEPLVQDLQAAVAAVQSAVHELLEFARSAVGNAAHTSDRALHAKLSRQLQKMEDVHQ 553 E + +++ AV V+ + E L F + AV NAA + LH K+ R+LQ++ED HQ Sbjct: 439 GY-MERHINEIRTAVDKVELFLKEYLHFVKGAVANAACLPELILHNKMKRELQRVEDSHQ 497 Query: 554 TLVAHGQALDAGRGGSGATL--------EDLDRLVACSRAVPEDAKQLASFLHGNASLLF 605 L L+ +DLDR V ++ VP+DAKQL + ++ NA LF Sbjct: 498 ILSQTSHDLNECSWSLNILAINKPQNKCDDLDRFVMVAKTVPDDAKQLTTTINTNAEALF 557 Query: 606 RRTKATAP---GPEG-------------GGTLHPNPTDKTSSIQSRPLPSPPKFTSQDSP 649 R + GPE G LHP D + ++ LP P + + +P Sbjct: 558 RPGPGSLHLKNGPESIMNSTEYPHGGSQGQLLHPG--DHKAQAHNKALP--PGLSKEQAP 613 Query: 650 D-GQYENSEGGWMEDYDYVHLQGKEEFEKTQKELLEKGSITRQGKSQLELQQLKQFERLE 708 D + SE WM+DYDYVHLQGKEEFE+ QKELLEK +I +Q K QLE QL QF+ LE Sbjct: 614 DCSSSDGSERSWMDDYDYVHLQGKEEFERQQKELLEKENIMKQNKMQLEHHQLSQFQLLE 673 Query: 709 QEVSRPIDHDLANWTPAQPLAPGRTGGLGPSDRQLLLFYLEQCEANLTTLTNAVDAFFTA 768 QE+++P+++D++ W P+Q L P G+ DRQLL FY +QCE + +L NA+DA F+ Sbjct: 674 QEITKPVENDISKWKPSQSL-PTTNSGVSAQDRQLLCFYYDQCETHFISLLNAIDALFSC 732 Query: 769 VATNQPPKIFVAHSKFVILSAHKLVFIGDTLSRQAKAADVRSQVTHYSNLLCDLLRGIVA 828 V++ QPP+IFVAHSKFVILSAHKLVFIGDTL+RQ A D+R++V + SN LC+ L+ IV Sbjct: 733 VSSAQPPRIFVAHSKFVILSAHKLVFIGDTLTRQVTAQDIRNKVMNSSNQLCEQLKTIVM 792 Query: 829 TTKAAALQYPSPSAAQDMVERVKELGHSTQQFRRVLGQLA 868 TK AAL YPS +A Q+MV +V +L + Q F+R L ++A Sbjct: 793 ATKMAALHYPSTTALQEMVHQVTDLSRNAQLFKRSLLEMA 832 >gi|215422375 neural precursor cell expressed, developmentally down-regulated 9 isoform 3 [Homo sapiens] Length = 834 Score = 514 bits (1323), Expect = e-145 Identities = 371/936 (39%), Positives = 489/936 (52%), Gaps = 180/936 (19%) Query: 5 NVLAKALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNRLKILV 64 N++A+ALYDNV E +EL+FRKGDI+TV+EQ+T GL+GWWLCSLHGRQGIVPGNR+K+L+ Sbjct: 5 NLMARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKLLI 64 Query: 65 GMYDKKPAGPGPGPPATPAQPQPGLHAPAPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQ 124 G P ++ QP GL + T+ Q Sbjct: 65 G--------PMQETASSHEQPASGL-------------MQQTF---------------GQ 88 Query: 125 QGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVPPGPGGPAQDIYQVPPS 184 Q LYQVP P +P +YQVPP Q IYQVP Sbjct: 89 QKLYQVPNPQA-----------------------APRDTIYQVPPSYQN--QGIYQVPTG 123 Query: 185 AG-MGHDIYQVPPSMDTRSWEGTKPP---AKVVVPTRVGQGYVYEAAQPEQDEYDIPRHL 240 G ++YQVPPS+ RS GT P KV+ P R G GYVYE Q Sbjct: 124 HGTQEQEVYQVPPSVQ-RSIGGTSGPHVGKKVITPVRTGHGYVYEYPSRYQ--------- 173 Query: 241 LAPGPQDIYDVPPVRGLLPSQYGQEVYDTPPMAVKGPNGRDPLLE-----VYDVPPSVEK 295 +D+YD+PP S Q VYD PP + KGP P+ E VYD+PP+ K Sbjct: 174 -----KDVYDIPP------SHTTQGVYDIPPSSAKGPVFSVPVGEIKPQGVYDIPPT--K 220 Query: 296 GLPPSNHHAVYDVPPSVSKDVPDGPLLREETYDVPPAFAKAKPFDPARTPLVLAAPPPDS 355 G VY +PPS +D LRE+ YD PP +A D R V PP + Sbjct: 221 G--------VYAIPPSACRDEAG---LREKDYDFPPPMRQAGRPD-LRPEGVYDIPPTCT 268 Query: 356 PPA-EDVY-----DVP----PPAPDLYDVPPGLRRPGPGT-------LYDVPR--ERVLP 396 PA +D++ D+P P A + P P G YDVPR + + P Sbjct: 269 KPAGKDLHVKYNCDIPGAAEPVARRHQSLSPNHPPPQLGQSVGSQNDAYDVPRGVQFLEP 328 Query: 397 P----EVADGGVVDSGVYAVP---PP---AEREAPAEGKRLSASSTGSTRSSQSASSLEV 446 P E A+ D GVY VP PP R+ RLS SSTGSTRS+ S SS Sbjct: 329 PAETSEKANPQERD-GVYDVPLHNPPDAKGSRDLVDGINRLSFSSTGSTRSNMSTSSTSS 387 Query: 447 ------AGPGREP---LELEVAVEALARLQQGVSATVAHLLDLAGSAGATGSWRSPSEPQ 497 A P ++ L+ + A+E L RLQQ + V+ L+ L T WR Sbjct: 388 KESSLSASPAQDKRLFLDPDTAIERLQRLQQALEMGVSSLMALV-----TTDWRCYGY-M 441 Query: 498 EPLVQDLQAAVAAVQSAVHELLEFARSAVGNAAHTSDRALHAKLSRQLQKMEDVHQTLVA 557 E + +++ AV V+ + E L F + AV NAA + LH K+ R+LQ++ED HQ L Sbjct: 442 ERHINEIRTAVDKVELFLKEYLHFVKGAVANAACLPELILHNKMKRELQRVEDSHQILSQ 501 Query: 558 HGQALDAGRGGSGATL--------EDLDRLVACSRAVPEDAKQLASFLHGNASLLFRRTK 609 L+ +DLDR V ++ VP+DAKQL + ++ NA LFR Sbjct: 502 TSHDLNECSWSLNILAINKPQNKCDDLDRFVMVAKTVPDDAKQLTTTINTNAEALFRPGP 561 Query: 610 ATAP---GPEG-------------GGTLHPNPTDKTSSIQSRPLPSPPKFTSQDSPD-GQ 652 + GPE G LHP D + ++ LP P + + +PD Sbjct: 562 GSLHLKNGPESIMNSTEYPHGGSQGQLLHPG--DHKAQAHNKALP--PGLSKEQAPDCSS 617 Query: 653 YENSEGGWMEDYDYVHLQGKEEFEKTQKELLEKGSITRQGKSQLELQQLKQFERLEQEVS 712 + SE WM+DYDYVHLQGKEEFE+ QKELLEK +I +Q K QLE QL QF+ LEQE++ Sbjct: 618 SDGSERSWMDDYDYVHLQGKEEFERQQKELLEKENIMKQNKMQLEHHQLSQFQLLEQEIT 677 Query: 713 RPIDHDLANWTPAQPLAPGRTGGLGPSDRQLLLFYLEQCEANLTTLTNAVDAFFTAVATN 772 +P+++D++ W P+Q L P G+ DRQLL FY +QCE + +L NA+DA F+ V++ Sbjct: 678 KPVENDISKWKPSQSL-PTTNSGVSAQDRQLLCFYYDQCETHFISLLNAIDALFSCVSSA 736 Query: 773 QPPKIFVAHSKFVILSAHKLVFIGDTLSRQAKAADVRSQVTHYSNLLCDLLRGIVATTKA 832 QPP+IFVAHSKFVILSAHKLVFIGDTL+RQ A D+R++V + SN LC+ L+ IV TK Sbjct: 737 QPPRIFVAHSKFVILSAHKLVFIGDTLTRQVTAQDIRNKVMNSSNQLCEQLKTIVMATKM 796 Query: 833 AALQYPSPSAAQDMVERVKELGHSTQQFRRVLGQLA 868 AAL YPS +A Q+MV +V +L + Q F+R L ++A Sbjct: 797 AALHYPSTTALQEMVHQVTDLSRNAQLFKRSLLEMA 832 >gi|239745060 PREDICTED: similar to breast cancer anti-estrogen resistance 1 [Homo sapiens] Length = 353 Score = 443 bits (1140), Expect = e-124 Identities = 206/211 (97%), Positives = 207/211 (98%) Query: 1 MNHLNVLAKALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNRL 60 MNHLNVLAKALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGI+PGN L Sbjct: 1 MNHLNVLAKALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIMPGNHL 60 Query: 61 KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPAPPASQYTPMLPNTYQPQPDSVYLVPTP 120 KILVGMYDKKPAGPGPGPPATPAQPQPGLHAP PPASQYTPMLPNTYQPQPDSVYLVPTP Sbjct: 61 KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTP 120 Query: 121 SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVPPGPGGPAQDIYQ 180 SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQV PGPGGPAQDIYQ Sbjct: 121 SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQ 180 Query: 181 VPPSAGMGHDIYQVPPSMDTRSWEGTKPPAK 211 VPPSAGMGHDIYQVP SMDTRSWEGTKPPAK Sbjct: 181 VPPSAGMGHDIYQVPSSMDTRSWEGTKPPAK 211 Score = 40.0 bits (92), Expect = 0.009 Identities = 54/200 (27%), Positives = 76/200 (38%), Gaps = 42/200 (21%) Query: 255 RGLLPSQYGQ---EVYDTPPMAVKGPNGRDPLLEVYDVPPSVEKGLPPSNHHA-----VY 306 +G++P + + +YD P GP G P P + +PP++ + Y Sbjct: 52 QGIMPGNHLKILVGMYDKKPA---GP-GPGPPATPAQPQPGLHAPVPPASQYTPMLPNTY 107 Query: 307 DVPPSVSKDVPDGPLLREETYDVP---------PA-----FAKAKPFDPARTP---LVLA 349 P VP ++ Y VP PA F+K P P +P L Sbjct: 108 QPQPDSVYLVPTPSKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQV 167 Query: 350 APPPDSPPAEDVYDVPPPA---PDLYDVPPGL-------RRPGPGTLYDVPRERVLPPEV 399 +P P P A+D+Y VPP A D+Y VP + +P P V R LPP Sbjct: 168 SPGPGGP-AQDIYQVPPSAGMGHDIYQVPSSMDTRSWEGTKP-PAKCASVSSPRCLPPR- 224 Query: 400 ADGGVVDSGVYAVPPPAERE 419 G +Y P PA E Sbjct: 225 GLGSPSFLLIYLSPAPARGE 244 >gi|239750776 PREDICTED: similar to breast cancer anti-estrogen resistance 1 [Homo sapiens] Length = 224 Score = 442 bits (1138), Expect = e-124 Identities = 207/212 (97%), Positives = 207/212 (97%) Query: 1 MNHLNVLAKALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNRL 60 MNHLNVLAKALY NVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGN L Sbjct: 1 MNHLNVLAKALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHL 60 Query: 61 KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPAPPASQYTPMLPNTYQPQPDSVYLVPTP 120 KILVGMYDKKPAGPGPGPPATPAQPQPGLHAP PPASQYTPMLPNTYQPQPDSVYLVPTP Sbjct: 61 KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTP 120 Query: 121 SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVPPGPGGPAQDIYQ 180 SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQV PGPGGPAQDIYQ Sbjct: 121 SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQ 180 Query: 181 VPPSAGMGHDIYQVPPSMDTRSWEGTKPPAKV 212 VPPSAGMGHDIYQVP SMDTRSWEGTKPPAKV Sbjct: 181 VPPSAGMGHDIYQVPSSMDTRSWEGTKPPAKV 212 Score = 36.6 bits (83), Expect = 0.10 Identities = 39/138 (28%), Positives = 54/138 (39%), Gaps = 30/138 (21%) Query: 266 VYDTPPMAVKGPNGRDPLLEVYDVPPSVEKGLPPSNHHA-----VYDVPPSVSKDVPDGP 320 +YD P GP G P P + +PP++ + Y P VP Sbjct: 66 MYDKKPA---GP-GPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPS 121 Query: 321 LLREETYDVP---------PA-----FAKAKPFDPARTP---LVLAAPPPDSPPAEDVYD 363 ++ Y VP PA F+K P P +P L +P P P A+D+Y Sbjct: 122 KAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGP-AQDIYQ 180 Query: 364 VPPPA---PDLYDVPPGL 378 VPP A D+Y VP + Sbjct: 181 VPPSAGMGHDIYQVPSSM 198 >gi|239756225 PREDICTED: similar to breast cancer anti-estrogen resistance 1 [Homo sapiens] Length = 232 Score = 441 bits (1134), Expect = e-123 Identities = 206/211 (97%), Positives = 206/211 (97%) Query: 1 MNHLNVLAKALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNRL 60 MNHLNVLAKALY NVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGN L Sbjct: 1 MNHLNVLAKALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHL 60 Query: 61 KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPAPPASQYTPMLPNTYQPQPDSVYLVPTP 120 KILVGMYDKKPAGPGPGPPATPAQPQPGLHAP PPASQYTPMLPNTYQPQPDSVYLVPTP Sbjct: 61 KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTP 120 Query: 121 SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVPPGPGGPAQDIYQ 180 SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQV PGPGGPAQDIYQ Sbjct: 121 SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQ 180 Query: 181 VPPSAGMGHDIYQVPPSMDTRSWEGTKPPAK 211 VPPSAGMGHDIYQVP SMDTRSWEGTKPPAK Sbjct: 181 VPPSAGMGHDIYQVPSSMDTRSWEGTKPPAK 211 Score = 36.6 bits (83), Expect = 0.10 Identities = 39/138 (28%), Positives = 54/138 (39%), Gaps = 30/138 (21%) Query: 266 VYDTPPMAVKGPNGRDPLLEVYDVPPSVEKGLPPSNHHA-----VYDVPPSVSKDVPDGP 320 +YD P GP G P P + +PP++ + Y P VP Sbjct: 66 MYDKKPA---GP-GPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPS 121 Query: 321 LLREETYDVP---------PA-----FAKAKPFDPARTP---LVLAAPPPDSPPAEDVYD 363 ++ Y VP PA F+K P P +P L +P P P A+D+Y Sbjct: 122 KAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGP-AQDIYQ 180 Query: 364 VPPPA---PDLYDVPPGL 378 VPP A D+Y VP + Sbjct: 181 VPPSAGMGHDIYQVPSSM 198 >gi|239745044 PREDICTED: similar to breast cancer anti-estrogen resistance 1 [Homo sapiens] Length = 368 Score = 441 bits (1134), Expect = e-123 Identities = 206/211 (97%), Positives = 206/211 (97%) Query: 1 MNHLNVLAKALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNRL 60 MNHLNVLAKALY NVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGN L Sbjct: 1 MNHLNVLAKALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHL 60 Query: 61 KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPAPPASQYTPMLPNTYQPQPDSVYLVPTP 120 KILVGMYDKKPAGPGPGPPATPAQPQPGLHAP PPASQYTPMLPNTYQPQPDSVYLVPTP Sbjct: 61 KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTP 120 Query: 121 SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVPPGPGGPAQDIYQ 180 SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQV PGPGGPAQDIYQ Sbjct: 121 SKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGPAQDIYQ 180 Query: 181 VPPSAGMGHDIYQVPPSMDTRSWEGTKPPAK 211 VPPSAGMGHDIYQVP SMDTRSWEGTKPPAK Sbjct: 181 VPPSAGMGHDIYQVPSSMDTRSWEGTKPPAK 211 Score = 39.7 bits (91), Expect = 0.012 Identities = 52/186 (27%), Positives = 69/186 (37%), Gaps = 39/186 (20%) Query: 266 VYDTPPMAVKGPNGRDPLLEVYDVPPSVEKGLPPSNHHA-----VYDVPPSVSKDVPDGP 320 +YD P GP G P P + +PP++ + Y P VP Sbjct: 66 MYDKKPA---GP-GPGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPS 121 Query: 321 LLREETYDVP---------PA-----FAKAKPFDPARTP---LVLAAPPPDSPPAEDVYD 363 ++ Y VP PA F+K P P +P L +P P P A+D+Y Sbjct: 122 KAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVSPGPGGP-AQDIYQ 180 Query: 364 VPPPA---PDLYDVPPGL-------RRPGPGTLYDVPRERVLPPEVADGGVVDSGVYAVP 413 VPP A D+Y VP + +P P V R LPP G +Y P Sbjct: 181 VPPSAGMGHDIYQVPSSMDTRSWEGTKP-PAKCASVSSPRCLPPR-GLGSPSFLLIYLSP 238 Query: 414 PPAERE 419 PA E Sbjct: 239 APARGE 244 >gi|55769585 HEF-like protein [Homo sapiens] Length = 786 Score = 199 bits (506), Expect = 9e-51 Identities = 228/903 (25%), Positives = 356/903 (39%), Gaps = 173/903 (19%) Query: 6 VLAKALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNRLKILVG 65 +LA+ALYDN + DEL+F +GDI+T+LEQ +GWW C LHGRQG+ P NRL+IL Sbjct: 14 LLARALYDNCPDCSDELAFSRGDILTILEQHVPESEGWWKCLLHGRQGLAPANRLQILTE 73 Query: 66 MYDKKPAGPG-PGPPATPAQPQPGLHAPAPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQ 124 + +P P G PA + P P P P Q S P P AQ Sbjct: 74 VAADRPCPPFLRGLEEAPASSEETYQVPTLP----RPPTPGPVYEQMRSWAEGPQPPTAQ 129 Query: 125 QGLYQVPGPSPQFQSPPAKQTSTFSKQ---TPHHP----FPSPATDLYQVPPGPGGPA-- 175 +Y+ P P P ++T +F KQ T P P+ + +Y VP GP Sbjct: 130 --VYEFPDP-PTSARIICEKTLSFPKQAILTLPRPVRASLPTLPSQVYDVPTQHRGPVVL 186 Query: 176 -----QDIYQVPPS---AGMGHDIYQVPPSMDTRSWEGTKPPAKVVVPTRVGQGYVYEAA 227 Q +Y +P S AG+ PP G P V R G Sbjct: 187 KEPEKQQLYDIPASPKKAGLH------PPDSQA---SGQGVPLISVTTLRRGGYSTLPNP 237 Query: 228 QPEQDEYDIPRHLLAPGPQDIYDVPPVRGLLPSQYGQEVYDTPPMAVKGPNGRDPLLEVY 287 Q + YD P ++PG + + P+ + + P+GR L Sbjct: 238 QKSEWIYDTP---VSPGKASVRNT-PLTSFAEESRPHALPSSSSTFYNPPSGRSRSL--- 290 Query: 288 DVPPSVEKGLPPSNHHAVYDVPPSVSKDVPDG--PLLREETYDVPPAFAKAKPFDPARTP 345 P + +P ++ ++ PS VP G PL + +Y VP +F Sbjct: 291 --TPQLNNNVPMQKKLSLPEI-PSYGFLVPRGTFPLDEDVSYKVPSSF------------ 335 Query: 346 LVLAAPPPDSPPAEDVYDVPPPAPDLYDVPPGLRRPGPGTLYDVPRERVLPPEVADGGVV 405 L+ ++ P ++YD+P ++ +E EV++ Sbjct: 336 LIPRVEQQNTKP--NIYDIP---------------KATSSVSQAGKELEKAKEVSENSAG 378 Query: 406 DSGVY-------AVPPPAEREAPAEGKRLSASSTGSTRSSQSASSLEVAGPGRE-PLELE 457 + + P P + R S S+ ST S+ +SS +E L+L+ Sbjct: 379 HNSSWFSRRTTSPSPEPDRLSGSSSDSRASIVSSCSTTSTDDSSSSSSEESAKELSLDLD 438 Query: 458 VAVEALARLQQGVSATVAHLLDLAGSAGATGSWRSPSEPQEPLVQDLQAAVAAVQSAVHE 517 VA E + LQ V ++VA L+ + WR + E + + + ++ +V E Sbjct: 439 VAKETVMALQHKVVSSVAGLM-----LFVSRKWRF-RDYLEANIDAIHRSTDHIEESVRE 492 Query: 518 LLEFARSAVGNAAHTSDRALHAKLSRQLQKMEDVHQTLVAHGQALDAGRGGSGATL---- 573 L+FAR G A + +D L ++ Q+Q + + ++ L+ ++LD R L Sbjct: 493 FLDFARGVHGTACNLTDSNLQNRIRDQMQTISNSYRILLETKESLD-NRNWPLEVLVTDS 551 Query: 574 -----EDLDRLVACSRAVPEDAKQLASFLHGNASLLFRR------TKATAPGPEGGGTLH 622 +DL+R V +R +PED K+ AS + N LLF+R T P E + Sbjct: 552 VQNSPDDLERFVMVARMLPEDIKRFASIVIANGRLLFKRNCEKEETVQLTPNAEFKCEKY 611 Query: 623 PNPTDKTSSIQSRPLPSPPKFTSQDSPDGQYENSEGGWMEDYDYVHLQGKEEFEKTQKEL 682 P + + + PS K+ ++ EL Sbjct: 612 IQPPQRETESHQKSTPST-------------------------------KQREDEHSSEL 640 Query: 683 LEKGSITRQGKSQLELQQLKQFERLEQEVSRPIDHDLANWTPAQPLAPGRTGGLGPSDRQ 742 L+K G++ PL P + P + Sbjct: 641 LKKNRANICGQN------------------------------PGPLIPQPSSQQTPERKP 670 Query: 743 LLLFYLEQCEANLTTLTNAVDAFFTAVATNQPPKIFVAHSKFVILSAHKLVFIGDTLSRQ 802 L E C L A+ AF +++++QP +I + SK VI+ KLV DTL + Sbjct: 671 RL---SEHCRLYFGALFKAISAFHGSLSSSQPAEI-ITQSKLVIMVGQKLV---DTLCME 723 Query: 803 AKAADVRSQVTHYSNLLCDLLRGIVATTKAAALQYPSPSAAQDMVERVKELGHSTQQFRR 862 + DVR+++ S+ LC LL+ + TK A L YPSP+A + ++L T+QFR Sbjct: 724 TQERDVRNEILRGSSHLCSLLKDVALATKNAVLTYPSPAALGHLQAEAEKLEQHTRQFRG 783 Query: 863 VLG 865 LG Sbjct: 784 TLG 786 >gi|5031681 embryonal Fyn-associated substrate isoform 1 [Homo sapiens] Length = 561 Score = 148 bits (373), Expect = 2e-35 Identities = 174/580 (30%), Positives = 235/580 (40%), Gaps = 117/580 (20%) Query: 329 VPPAFAKAKPFDPARTPLVLAAPP--PDSP-PAED-------VYDVPPPA-PDLYDVPP- 376 VP K P PA P + A P P SP PA D VY VPPPA P PP Sbjct: 58 VPANRVKLLPAGPAPKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPCPTSGPPA 117 Query: 377 GLRRPGPGTLYDVPR----ERVLPPEVADGGVVDSGVYAVPPPAEREAPAEGKRLSASST 432 G P P +Y +PR + P + + VY VPP A R P+ G +S Sbjct: 118 GPCPPSPDLIYKIPRASGTQLAAPRDALE-------VYDVPPTALR-VPSSGPYDCPASF 169 Query: 433 GSTRSSQSASSLEVAGPGRE--PLELEVAVEALARLQQGVSATVAHLLDLAGSAGATGSW 490 S + + PG + P ++ + + A L+ DL G Sbjct: 170 -----SHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEP----------DLEWEGG----- 209 Query: 491 RSPSEPQEPLVQDLQAAVAAVQ--SAVHELLEFARSAVGNAAHTSDRALHAKL-SRQLQK 547 R P P +L+ A A + A ELL A G T + L + Sbjct: 210 REPGPPIYAAPSNLKRASALLNLYEAPEELL-----ADGEGGGTDEGIYDVPLLGPEAPP 264 Query: 548 MEDVHQTLVAHGQALDAGRGGSGATLEDLDRLVACSRAVPEDAKQLASFLHGNASLLFRR 607 + L +H Q + L +L+A S P + +A L RR Sbjct: 265 SPEPPGALASHDQ-------------DTLAQLLARSPPPPHRPRL------PSAESLSRR 305 Query: 608 TKATAPGPEGGGTLH-PNPTD-KTSSIQSRPLPSPPKFTS----------------QDSP 649 P PE P+P + SIQ RPLP PP +D P Sbjct: 306 PLPALPVPEAPSPSPVPSPAPGRKGSIQDRPLPPPPPRLPGYGGPKVEGDPEGREMEDDP 365 Query: 650 DGQYENSEGGWM-EDYDYVHLQGKEEFEKTQKELLEKGSITRQGKSQLELQQLKQFERLE 708 G + EG M E+YDYVHL+G +K Q + T G +L + + Sbjct: 366 AGHHNEYEGIPMAEEYDYVHLKG---MDKAQGSRPPDQACT--GDPELPERGMP------ 414 Query: 709 QEVSRPIDHDLANWTPAQPLAPGRTGGLGPSDRQLLLFYLEQCEANLTTLTNAVDAFFTA 768 P + L+PG + D QLL FY QC+++ + L AV A ++ Sbjct: 415 --------------APQEALSPGEPLVVSTGDLQLLYFYAGQCQSHYSALQAAVAALMSS 460 Query: 769 VATNQPPKIFVAHSKFVILSAHKLVFIGDTLSRQAKAADVRSQVTHYSNLLCDLLRGIVA 828 NQPP++FV HSK V+++AH+LVF+GDTL R A +A +R+QV L LR V Sbjct: 461 TQANQPPRLFVPHSKRVVVAAHRLVFVGDTLGRLAASAPLRAQVRAAGTALGQALRATVL 520 Query: 829 TTKAAALQYPSPSAAQDMVERVKELGHSTQQFRRVLGQLA 868 K AAL YPS A Q+MV+ V EL QF +L LA Sbjct: 521 AVKGAALGYPSSPAIQEMVQCVTELAGQALQFTTLLTSLA 560 Score = 134 bits (336), Expect = 5e-31 Identities = 126/405 (31%), Positives = 172/405 (42%), Gaps = 88/405 (21%) Query: 7 LAKALYDNVAESPDELSFRKGDIMTVLEQD-TQGLDGWWLCSLHGRQGIVPGNRLKILVG 65 LA+ALYDN AESP ELSFR+GD++ VL+++ GLDGW LCSLHG+QGIVP NR+K+L Sbjct: 9 LARALYDNTAESPQELSFRRGDVLRVLQREGAGGLDGWCLCSLHGQQGIVPANRVKLL-- 66 Query: 66 MYDKKPAGPGPGPPATPAQP-QPGLHAPAPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQ 124 PAGP P P +PA P QPG PAP S + VY+VP P++ Sbjct: 67 -----PAGPAPKPSLSPASPAQPGSPYPAPDHSN-----------EDQEVYVVPPPAR-- 108 Query: 125 QGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVPPGPG------GPAQDI 178 P P+ PPA P P +Y++P G A ++ Sbjct: 109 ------PCPT---SGPPA------------GPCPPSPDLIYKIPRASGTQLAAPRDALEV 147 Query: 179 YQVPPSAGMGHDIYQVPPSMDTRSWEGTKPPAKVVVPTRVGQGYVYEAAQPEQDEYDIPR 238 Y VPP+A +VP S P V P G+ + YD+P Sbjct: 148 YDVPPTA------LRVPSSGPYDCPASFSHPLTRVAPQPPGE---------DDAPYDVP- 191 Query: 239 HLLAPGPQDIYDVPPVRGLLPSQYGQEVYDTPPMAVKGPNGRDPLLEVYDVPPS-VEKGL 297 L P P + P + + G +Y P + LL +Y+ P + G Sbjct: 192 --LTPKPPAELE-PDLEWEGGREPGPPIYAAPSNLKRA----SALLNLYEAPEELLADGE 244 Query: 298 PPSNHHAVYDVPPSVSKDVPDGPLLREETYDVPPAFAKAKPFDPARTPLVLAAPPPDS-- 355 +YDV P + + P P PP + D L + PPP Sbjct: 245 GGGTDEGIYDV-PLLGPEAPPSP--------EPPGALASHDQDTLAQLLARSPPPPHRPR 295 Query: 356 -PPAEDVYDVPPPAPDLYDV--PPGLRRPGPGTLYDVPRERVLPP 397 P AE + P PA + + P + P PG + ++R LPP Sbjct: 296 LPSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKGSI-QDRPLPP 339 >gi|14589876 embryonal Fyn-associated substrate isoform 2 [Homo sapiens] Length = 468 Score = 140 bits (354), Expect = 4e-33 Identities = 160/541 (29%), Positives = 220/541 (40%), Gaps = 107/541 (19%) Query: 358 AEDVYDVPPPA-PDLYDVPP-GLRRPGPGTLYDVPR----ERVLPPEVADGGVVDSGVYA 411 A VY VPPPA P PP G P P +Y +PR + P + + VY Sbjct: 4 ATSVYVVPPPARPCPTSGPPAGPCPPSPDLIYKIPRASGTQLAAPRDALE-------VYD 56 Query: 412 VPPPAEREAPAEGKRLSASSTGSTRSSQSASSLEVAGPGRE--PLELEVAVEALARLQQG 469 VPP A R P+ G +S S + + PG + P ++ + + A L+ Sbjct: 57 VPPTALR-VPSSGPYDCPASF-----SHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEP- 109 Query: 470 VSATVAHLLDLAGSAGATGSWRSPSEPQEPLVQDLQAAVAAVQ--SAVHELLEFARSAVG 527 DL G R P P +L+ A A + A ELL A G Sbjct: 110 ---------DLEWEGG-----REPGPPIYAAPSNLKRASALLNLYEAPEELL-----ADG 150 Query: 528 NAAHTSDRALHAKL-SRQLQKMEDVHQTLVAHGQALDAGRGGSGATLEDLDRLVACSRAV 586 T + L + + L +H Q + L +L+A S Sbjct: 151 EGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQ-------------DTLAQLLARSPPP 197 Query: 587 PEDAKQLASFLHGNASLLFRRTKATAPGPEGGGTLH-PNPTD-KTSSIQSRPLPSPPKFT 644 P + +A L RR P PE P+P + SIQ RPLP PP Sbjct: 198 PHRPRL------PSAESLSRRPLPALPVPEAPSPSPVPSPAPGRKGSIQDRPLPPPPPRL 251 Query: 645 S----------------QDSPDGQYENSEGGWM-EDYDYVHLQGKEEFEKTQKELLEKGS 687 +D P G + EG M E+YDYVHL+G +K Q + Sbjct: 252 PGYGGPKVEGDPEGREMEDDPAGHHNEYEGIPMAEEYDYVHLKG---MDKAQGSRPPDQA 308 Query: 688 ITRQGKSQLELQQLKQFERLEQEVSRPIDHDLANWTPAQPLAPGRTGGLGPSDRQLLLFY 747 T G +L + + P + L+PG + D QLL FY Sbjct: 309 CT--GDPELPERGMP--------------------APQEALSPGEPLVVSTGDLQLLYFY 346 Query: 748 LEQCEANLTTLTNAVDAFFTAVATNQPPKIFVAHSKFVILSAHKLVFIGDTLSRQAKAAD 807 QC+++ + L AV A ++ NQPP++FV HSK V+++AH+LVF+GDTL R A +A Sbjct: 347 AGQCQSHYSALQAAVAALMSSTQANQPPRLFVPHSKRVVVAAHRLVFVGDTLGRLAASAP 406 Query: 808 VRSQVTHYSNLLCDLLRGIVATTKAAALQYPSPSAAQDMVERVKELGHSTQQFRRVLGQL 867 +R+QV L LR V K AAL YPS A Q+MV+ V EL QF +L L Sbjct: 407 LRAQVRAAGTALGQALRATVLAVKGAALGYPSSPAIQEMVQCVTELAGQALQFTTLLTSL 466 Query: 868 A 868 A Sbjct: 467 A 467 Score = 42.7 bits (99), Expect = 0.001 Identities = 93/383 (24%), Positives = 131/383 (34%), Gaps = 94/383 (24%) Query: 71 PAGPGP--GPPATPAQPQPGLHAPAPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQGLY 128 PA P P GPPA P P P L P AS P D++ + P A Sbjct: 13 PARPCPTSGPPAGPCPPSPDLIYKIPRASGTQLAAPR------DALEVYDVPPTA----L 62 Query: 129 QVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVPPGPGGPAQDIYQVP-PSAGM 187 +VP P + P + F P T + PPG D+ P P A + Sbjct: 63 RVPSSGP-YDCPAS--------------FSHPLTRVAPQPPGEDDAPYDVPLTPKPPAEL 107 Query: 188 GHDIYQVPPSMDTRSWEGTKPPAKVV--VPTRVGQGYVYEAAQPEQDEYDIPRHLLAPG- 244 D+ WEG + P + P+ + + A + Y+ P LLA G Sbjct: 108 EPDL----------EWEGGREPGPPIYAAPSNL------KRASALLNLYEAPEELLADGE 151 Query: 245 ----PQDIYDVPPVRGLLPSQYGQEVYDTP-PMAVKGPNGRDPLLEVY--DVPPSVEKGL 297 + IYDVP + G E +P P + +D L ++ PP L Sbjct: 152 GGGTDEGIYDVPLL--------GPEAPPSPEPPGALASHDQDTLAQLLARSPPPPHRPRL 203 Query: 298 PPSNHHAVYDVPPSVSKDVPDGPLLREETYDVP-PAFAKAKPFDPARTPLVLAAPPPDSP 356 P + + +P + VP+ P VP PA P R + P P P Sbjct: 204 PSAESLSRRPLP---ALPVPEAP----SPSPVPSPA--------PGRKGSIQDRPLPPPP 248 Query: 357 PAEDVYDVP-----PPAPDLYDVPPGLRRPGPG----TLYDVPRERVL-------PPEVA 400 P Y P P ++ D P G G YD + + PP+ A Sbjct: 249 PRLPGYGGPKVEGDPEGREMEDDPAGHHNEYEGIPMAEEYDYVHLKGMDKAQGSRPPDQA 308 Query: 401 DGGVVDSGVYAVPPPAEREAPAE 423 G + +P P E +P E Sbjct: 309 CTGDPELPERGMPAPQEALSPGE 331 >gi|78486553 neural precursor cell expressed, developmentally down-regulated 9 isoform 2 [Homo sapiens] Length = 174 Score = 130 bits (328), Expect = 4e-30 Identities = 75/159 (47%), Positives = 96/159 (60%), Gaps = 15/159 (9%) Query: 1 MNHLNVLAKALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNRL 60 M + N++A+ALYDNV E +EL+FRKGDI+TV+EQ+T GL+GWWLCSLHGRQGIVPGNR+ Sbjct: 1 MKYKNLMARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRV 60 Query: 61 KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPAPPASQYTPMLPNTYQPQPDSVYLVPTP 120 K+L+ GP ++ QP GL Q +PN D++Y VP P Sbjct: 61 KLLI--------GPMQETASSHEQPASGL-MQQTFGQQKLYQVPNPQAAPRDTIYQVP-P 110 Query: 121 SKAQQGLYQVP---GPSPQ--FQSPPAKQTSTFSKQTPH 154 S QG+YQVP G Q +Q PP+ Q S PH Sbjct: 111 SYQNQGIYQVPTGHGTQEQEVYQVPPSVQRSIGGTSGPH 149 Score = 38.1 bits (87), Expect = 0.036 Identities = 30/91 (32%), Positives = 40/91 (43%), Gaps = 5/91 (5%) Query: 124 QQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSP--ATDLYQVPPGPGGPAQDIYQV 181 +QG+ VPG + P ++T++ +Q LYQVP P IYQV Sbjct: 51 RQGI--VPGNRVKLLIGPMQETASSHEQPASGLMQQTFGQQKLYQVPNPQAAPRDTIYQV 108 Query: 182 PPSAGMGHDIYQVPPSMDTRSWEGTKPPAKV 212 PPS IYQVP T+ E + P V Sbjct: 109 PPSY-QNQGIYQVPTGHGTQEQEVYQVPPSV 138 Score = 32.7 bits (73), Expect = 1.5 Identities = 25/73 (34%), Positives = 36/73 (49%), Gaps = 16/73 (21%) Query: 253 PVRGLLPSQYGQE-VYDTP-PMAVKGPNGRDPLLEVYDVPPSVE-KGL--PPSNH----H 303 P GL+ +GQ+ +Y P P A P +Y VPPS + +G+ P+ H Sbjct: 77 PASGLMQQTFGQQKLYQVPNPQAA-------PRDTIYQVPPSYQNQGIYQVPTGHGTQEQ 129 Query: 304 AVYDVPPSVSKDV 316 VY VPPSV + + Sbjct: 130 EVYQVPPSVQRSI 142 Score = 30.8 bits (68), Expect = 5.7 Identities = 23/68 (33%), Positives = 31/68 (45%), Gaps = 13/68 (19%) Query: 230 EQDEYDIPRHLLAPGPQDIYDVPPVRGLLPSQYGQEVYDTPPMAVKGPNGRDPLLEVYDV 289 +Q Y +P AP IY VPP S Q +Y P G ++ EVY V Sbjct: 88 QQKLYQVPNPQAAPR-DTIYQVPP------SYQNQGIYQVPT----GHGTQEQ--EVYQV 134 Query: 290 PPSVEKGL 297 PPSV++ + Sbjct: 135 PPSVQRSI 142 >gi|47132519 Ras association and pleckstrin homology domains 1 isoform 1 [Homo sapiens] Length = 1250 Score = 73.6 bits (179), Expect = 8e-13 Identities = 103/473 (21%), Positives = 152/473 (32%), Gaps = 46/473 (9%) Query: 61 KILVGMYDKKPAGPGPGPPATPAQPQPGLHAPAPPASQYTPMLPNTYQP---QPDSVYLV 117 KI+ +P+ P P PP P P P P PP + + P + ++ + Sbjct: 614 KIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRL 673 Query: 118 PTPSKAQQGLYQVPGP--------SPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVPP 169 S+ L++ P P PQ PP P P P+P + + Q+ P Sbjct: 674 QNASQHSGALFKPPTPPVMQSQSVKPQILVPP---NGVVPPPPPPPPPPTPGSAMAQLKP 730 Query: 170 GPGGPAQDIYQVPPSAGMGHDIYQV----PPSMDTRSWEGTKPPAKVVVPTRVGQGYVYE 225 P P+ + PP H + + PP+ PP +P + + Sbjct: 731 APCAPSLPQFSAPPPPLKIHQVQHITQVAPPT------PPPPPPIPAPLPPQAPPKPLVT 784 Query: 226 AAQPEQDEYDIPRHLLAPGPQDIYDVPPVR--GLLPSQYGQEVYDTPPMAVKGPNGRDPL 283 P + P A P VPP + P+ Y TPP+ V P Sbjct: 785 IPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQ 844 Query: 284 LEVYDVPPSVEKGLPPSNHHAVYDVPPSVSKDVPDGPLLREETYDVPPAFAKAKPFDPAR 343 PPS +P PP + + L+ +V P A P Sbjct: 845 SFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKW 904 Query: 344 TPLVLAAPPPD--SPPAEDVYDVPPPAPDLYDVPPGLRRPGPGTLYDVPRERVLPPEVAD 401 P + P PD PP E PPP P PP P P T P + P + Sbjct: 905 QPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPP---PPPPPTASPTPDKSGSPGKKTS 961 Query: 402 GGVVDSGVYAVPPP--------------AEREAPAEGKRLSASSTGSTRSSQSASSLEVA 447 G P P E + P+ +S + + S S +L Sbjct: 962 KTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPP 1021 Query: 448 GPGREPLELEVA-VEALARLQQGVSATVAHLLDLAGSAGATGSWRSPSEPQEP 499 +P +L ++ V LQQG + A +L G PS+ P Sbjct: 1022 AAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFP 1074 Score = 52.8 bits (125), Expect = 1e-06 Identities = 103/474 (21%), Positives = 142/474 (29%), Gaps = 124/474 (26%) Query: 71 PAGPGPGPPATPAQPQPGLHAPAPPASQYTPM--LPNTYQPQPDSVYLVPTPSKAQQGLY 128 P P P PP P+Q P + AP +Y+ + L N Q +++ PTP + Sbjct: 639 PPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQ-HSGALFKPPTPP-----VM 692 Query: 129 QVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVPPGPGGPAQDIYQVPPSAGMG 188 Q PQ PP P P P+P + + Q+ P P P+ + PP Sbjct: 693 QSQSVKPQILVPP---NGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKI 749 Query: 189 HDIYQV----PPSMDTRSWEGTKPPAKVVVPTRVGQGYVYEAAQPEQDEYDIPRHLLAPG 244 H + + PP+ PP +P + + P + P A Sbjct: 750 HQVQHITQVAPPTPPP------PPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAP 803 Query: 245 PQDIYDVPPVRG--LLPSQYGQEVYDTPPMAVKGPN-----------GRDPLLEVYDVPP 291 P VPP + P+ Y TPP+ V P PL V V Sbjct: 804 PTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVK 863 Query: 292 SVEKGLPPS------NHHAVYDVPPSVSKDVPDG----PLLREETYDVP-PAFAKAKP-- 338 + PP + VP +V+ P P + + VP P F P Sbjct: 864 QIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPES 923 Query: 339 ---FDPARTPLVLAAPPPDSPPAEDVYDV------------------PPPAPDLYDV--- 374 F P V A PPP P A D PPP P Sbjct: 924 SLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKS 983 Query: 375 -----PPGLRRPGPGTLYDV---------PRERVLPPEVADG-------------GVVDS 407 P +RP +L P + LPP A GV+ Sbjct: 984 SSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQ 1043 Query: 408 GVYAV--------------------------PPPAEREAPAEGKRLSASSTGST 435 G + PPP E E P + A +G+T Sbjct: 1044 GCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNT 1097 Score = 45.8 bits (107), Expect = 2e-04 Identities = 92/375 (24%), Positives = 128/375 (34%), Gaps = 85/375 (22%) Query: 72 AGPGPGPPATPAQPQPGLHAPAPPASQYTPMLPNTYQPQPDSVYLVPTPS-KAQQGLYQV 130 A P P PP PA+ QP A P S TP +P VP P+ QQ Sbjct: 802 APPTPTPPVPPAKKQPAFPASYIPPSPPTPPVP------------VPPPTLPKQQSFCAK 849 Query: 131 PGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVPPGPGGPAQDIYQVPPSAGMGHD 190 P PSP SP + Q P P P PA + + P P A Sbjct: 850 PPPSPL--SPVPSVVKQIASQFPPPPTP-PAMESQPLKPVPANVAP-------------- 892 Query: 191 IYQVPPSMDTR-SWEGTKPPAKVVVPTRVGQGYVYEAAQPEQDEYDIPRHLLAPGPQDIY 249 Q PP++ + W+ P+ + VP+ P + P +P P Sbjct: 893 --QSPPAVKAKPKWQ----PSSIPVPSPDFP------PPPPESSLVFPPPPPSPVPAPPP 940 Query: 250 DVPPVRGLLPSQYGQEVYDTPPMAVKGPNGRDPLLEVYDVPPSVEKGLP-PSNHHAVYDV 308 PP P + G T + P G+ P PP+ ++ S+ A + Sbjct: 941 PPPPTASPTPDKSGSPGKKTSKTS--SPGGKKP-------PPTPQRNSSIKSSSGAEHPE 991 Query: 309 P--PSV----SKDVPDGPLLREETYDVPPAFAKAKP----FDPARTPLVL-----AAPPP 353 P PSV SK P +PP A KP P VL +A P Sbjct: 992 PKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAP 1051 Query: 354 -------------DSPPAEDVYDVPPPAPDLYDVPPGLRRPGPGTLYDVPRERVLPPEVA 400 SPP++ + PPP +L +PP + P + P+ V+ P+ Sbjct: 1052 VLSGRGKDSVVEFPSPPSDSDFPPPPPETEL-PLPP-IEIPAVFSGNTSPKVAVVNPQPQ 1109 Query: 401 DGGVVDSGVYAVPPP 415 + V PPP Sbjct: 1110 QWSKM--SVKKAPPP 1122 >gi|242117953 SH3 domain-containing protein C1orf113 isoform 1 [Homo sapiens] Length = 756 Score = 72.0 bits (175), Expect = 2e-12 Identities = 97/386 (25%), Positives = 143/386 (37%), Gaps = 63/386 (16%) Query: 9 KALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNRLKILVGMYD 68 + L+D E+PDEL+ R+GD++ VL + T+ GWW GR+G+ P N + Sbjct: 187 RVLFDYQPEAPDELALRRGDVVKVLSKTTED-KGWWEGECQGRRGVFPDNFVL------- 238 Query: 69 KKPAGPGPGPPATPAQPQPGLHAPAPPASQYTPMLPNTYQPQ----------PDSVYLVP 118 P PP P+ + + P + ++P T P P Sbjct: 239 -------PPPPIKKLVPRKVVSRESAPIKEPKKLMPKTSLPTVKKLATATTGPSKAKTSR 291 Query: 119 TPSKAQQGL-YQVPGPSPQFQS-----PPAKQTST-------FSKQTPHHPFPSPATDLY 165 TPS+ Q L + GP+ FQS P K++ T S Q H P A + Sbjct: 292 TPSRDSQKLTSRDSGPNGGFQSGGSYHPGRKRSKTQTPQQRSVSSQEEEHSSPVKAPSVK 351 Query: 166 QVPPGPGGPAQDIYQVPPSAGMGHDI---YQVPPSM------DTRSWEGTKPPAKVVVPT 216 + P + P +A I +VP D S G K+ P Sbjct: 352 RTPMPDKTATPERPPAPENAPSSKKIPAPDKVPSPEKTLTLGDKASIPGNSTSGKIPAPD 411 Query: 217 RVGQGYVYEAAQPEQDEYDIPRHLLAPGPQDIYDVPPVRGLLPSQYGQEVYDTPPMAVKG 276 +V E +D+ IP + + P D P + S + PPM K Sbjct: 412 KVP---TPEKMVTPEDKASIPENSIIPEETLTVDKPSTPERVFSVEESPALEAPPMD-KV 467 Query: 277 PNGRDPLLEVYDVPPSVEKGLPPSNHHAVYDVPPSVSKDVPDGPLLREETYDVPPAF-AK 335 PN + + + D P++EK L P + + S D+ EE F AK Sbjct: 468 PNPK--MAPLGDEAPTLEKVLTPE----LSEEEVSTRDDIQFHHFSSEEALQKVKYFVAK 521 Query: 336 AKPF--DPARTPLVLAAPPPDSPPAE 359 P + A TP APPP P +E Sbjct: 522 EDPSSQEEAHTP---EAPPPQPPSSE 544 Score = 41.2 bits (95), Expect = 0.004 Identities = 96/429 (22%), Positives = 150/429 (34%), Gaps = 77/429 (17%) Query: 17 ESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNRLKIL------VGMYDKK 70 E DEL + G+I+ ++++ DGWWL +G+ G P N +++L +G D Sbjct: 97 EQADELKLQAGEIVEMIKEIE---DGWWLGKKNGQLGAFPSNFVELLDSGPPSLGNPDMP 153 Query: 71 PAGPGPGPPATPAQPQPGLHAPAPPASQYTPMLPNT------YQPQ-PDSVYL------- 116 PGP P + L +PP T P YQP+ PD + L Sbjct: 154 SVSPGPQRPPKLS----SLAYDSPPDYLQTVSHPEVYRVLFDYQPEAPDELALRRGDVVK 209 Query: 117 VPTPSKAQQGLYQ--------------VPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPAT 162 V + + +G ++ V P P + P K S S P T Sbjct: 210 VLSKTTEDKGWWEGECQGRRGVFPDNFVLPPPPIKKLVPRKVVSRESAPIKEPKKLMPKT 269 Query: 163 DL---YQVPPGPGGPAQDIYQVPPSAGMGHDIYQVPPSMDTRSWEGTKPPAKVVVPTRVG 219 L ++ GP++ PS + G+ P + T+ Sbjct: 270 SLPTVKKLATATTGPSKAKTSRTPSRDSQKLTSRDSGPNGGFQSGGSYHPGRKRSKTQTP 329 Query: 220 QGYVYEAAQPEQDEYDIPRHLLAPG----PQDIYDVPPVRGLLPSQYGQEVYDTPPMAVK 275 Q + +++E+ P + AP P P R P P V Sbjct: 330 Q---QRSVSSQEEEHSSP--VKAPSVKRTPMPDKTATPERPPAPENAPSSKKIPAPDKVP 384 Query: 276 GPNGRDPLLEVYDVPPSVEKGLPPSNHHAVYD---VPPSVSKDVPDGPLLREETYDVPPA 332 P L + +P + G P+ V P +P+ ++ EET V Sbjct: 385 SPEKTLTLGDKASIPGNSTSGKIPAPDKVPTPEKMVTPEDKASIPENSIIPEETLTVD-- 442 Query: 333 FAKAKPFDPARTPLVLAAPPPDSPPAEDVYDVPPPAPDLYDVPPGLRRPGPGTLYDVPRE 392 KP P R V +P ++PP + V + P AP L D P L E Sbjct: 443 ----KPSTPERVFSVEESPALEAPPMDKVPN-PKMAP-LGDEAPTL-------------E 483 Query: 393 RVLPPEVAD 401 +VL PE+++ Sbjct: 484 KVLTPELSE 492 >gi|242117948 SH3 domain-containing protein C1orf113 isoform 2 [Homo sapiens] Length = 645 Score = 72.0 bits (175), Expect = 2e-12 Identities = 97/386 (25%), Positives = 143/386 (37%), Gaps = 63/386 (16%) Query: 9 KALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNRLKILVGMYD 68 + L+D E+PDEL+ R+GD++ VL + T+ GWW GR+G+ P N + Sbjct: 76 RVLFDYQPEAPDELALRRGDVVKVLSKTTED-KGWWEGECQGRRGVFPDNFVL------- 127 Query: 69 KKPAGPGPGPPATPAQPQPGLHAPAPPASQYTPMLPNTYQPQ----------PDSVYLVP 118 P PP P+ + + P + ++P T P P Sbjct: 128 -------PPPPIKKLVPRKVVSRESAPIKEPKKLMPKTSLPTVKKLATATTGPSKAKTSR 180 Query: 119 TPSKAQQGL-YQVPGPSPQFQS-----PPAKQTST-------FSKQTPHHPFPSPATDLY 165 TPS+ Q L + GP+ FQS P K++ T S Q H P A + Sbjct: 181 TPSRDSQKLTSRDSGPNGGFQSGGSYHPGRKRSKTQTPQQRSVSSQEEEHSSPVKAPSVK 240 Query: 166 QVPPGPGGPAQDIYQVPPSAGMGHDI---YQVPPSM------DTRSWEGTKPPAKVVVPT 216 + P + P +A I +VP D S G K+ P Sbjct: 241 RTPMPDKTATPERPPAPENAPSSKKIPAPDKVPSPEKTLTLGDKASIPGNSTSGKIPAPD 300 Query: 217 RVGQGYVYEAAQPEQDEYDIPRHLLAPGPQDIYDVPPVRGLLPSQYGQEVYDTPPMAVKG 276 +V E +D+ IP + + P D P + S + PPM K Sbjct: 301 KVP---TPEKMVTPEDKASIPENSIIPEETLTVDKPSTPERVFSVEESPALEAPPMD-KV 356 Query: 277 PNGRDPLLEVYDVPPSVEKGLPPSNHHAVYDVPPSVSKDVPDGPLLREETYDVPPAF-AK 335 PN + + + D P++EK L P + + S D+ EE F AK Sbjct: 357 PNPK--MAPLGDEAPTLEKVLTPE----LSEEEVSTRDDIQFHHFSSEEALQKVKYFVAK 410 Query: 336 AKPF--DPARTPLVLAAPPPDSPPAE 359 P + A TP APPP P +E Sbjct: 411 EDPSSQEEAHTP---EAPPPQPPSSE 433 Score = 33.9 bits (76), Expect = 0.67 Identities = 90/405 (22%), Positives = 137/405 (33%), Gaps = 74/405 (18%) Query: 41 DGWWLCSLHGRQGIVPGNRLKIL------VGMYDKKPAGPGPGPPATPAQPQPGLHAPAP 94 DGWWL +G+ G P N +++L +G D PGP P + L +P Sbjct: 7 DGWWLGKKNGQLGAFPSNFVELLDSGPPSLGNPDMPSVSPGPQRPPKLS----SLAYDSP 62 Query: 95 PASQYTPMLPNT------YQPQ-PDSVYL-------VPTPSKAQQGLYQ----------- 129 P T P YQP+ PD + L V + + +G ++ Sbjct: 63 PDYLQTVSHPEVYRVLFDYQPEAPDELALRRGDVVKVLSKTTEDKGWWEGECQGRRGVFP 122 Query: 130 ---VPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDL---YQVPPGPGGPAQDIYQVPP 183 V P P + P K S S P T L ++ GP++ P Sbjct: 123 DNFVLPPPPIKKLVPRKVVSRESAPIKEPKKLMPKTSLPTVKKLATATTGPSKAKTSRTP 182 Query: 184 SAGMGHDIYQVPPSMDTRSWEGTKPPAKVVVPTRVGQGYVYEAAQPEQDEYDIPRHLLAP 243 S + G+ P + T+ Q + +++E+ P + AP Sbjct: 183 SRDSQKLTSRDSGPNGGFQSGGSYHPGRKRSKTQTPQ---QRSVSSQEEEHSSP--VKAP 237 Query: 244 G----PQDIYDVPPVRGLLPSQYGQEVYDTPPMAVKGPNGRDPLLEVYDVPPSVEKGLPP 299 P P R P P V P L + +P + G P Sbjct: 238 SVKRTPMPDKTATPERPPAPENAPSSKKIPAPDKVPSPEKTLTLGDKASIPGNSTSGKIP 297 Query: 300 SNHHAVYD---VPPSVSKDVPDGPLLREETYDVPPAFAKAKPFDPARTPLVLAAPPPDSP 356 + V P +P+ ++ EET V KP P R V +P ++P Sbjct: 298 APDKVPTPEKMVTPEDKASIPENSIIPEETLTVD------KPSTPERVFSVEESPALEAP 351 Query: 357 PAEDVYDVPPPAPDLYDVPPGLRRPGPGTLYDVPRERVLPPEVAD 401 P + V + P AP L D P L E+VL PE+++ Sbjct: 352 PMDKVPN-PKMAP-LGDEAPTL-------------EKVLTPELSE 381 >gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 855 Score = 72.0 bits (175), Expect = 2e-12 Identities = 114/456 (25%), Positives = 156/456 (34%), Gaps = 75/456 (16%) Query: 69 KKPAGPGPGP----PATPAQPQPGLHAPAPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQ 124 +K A P GP P P L + APP TP + + L P A Sbjct: 289 RKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAP 348 Query: 125 QGLYQVPGPSPQFQSPPAKQTSTFSK---QTPHHPFPSPATDLYQVPPGPGGPAQDI--Y 179 L +P P +PP++ T++ Q H PSP PP PA + Sbjct: 349 PSLQTLPSPP---ATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPL 405 Query: 180 QVPPSAGMGHDIYQVPPSMDTRSWEGT-KPPAKVVVPTRVGQG-YVYEAAQPEQDEYDIP 237 Q PPS PP+ S T P A + + Q + + P Q + P Sbjct: 406 QAPPS----------PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPP 455 Query: 238 RH-LLAPGPQDIYDVPPVRGLLPSQYGQEVYDTPPM---AVKGPNGRDPLLEVYDVPPSV 293 ++P PP P Q +PPM A P PL P + Sbjct: 456 ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPL-----AAPPL 510 Query: 294 EKGLPPSNHHAVYDVPPSVSKDVPDGPLLREETYDVPPAFAKAKPFDP-ARTPL-VLAAP 351 + PP PP + P P +F PF P A P+ LA P Sbjct: 511 QLAKPPPQAPPALATPPLQALPSP------------PASFPGQAPFSPSASLPMSPLATP 558 Query: 352 PPDSPP--AEDVYDVP--PPAPDLYDVPPGLRRPGPGTLYDVPRERVLPPEVADGGVVDS 407 PP +PP A + VP PPA P PGP T PR L +A G Sbjct: 559 PPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPR---LTLALAPG----- 610 Query: 408 GVYAVPPPAEREAPA---EGKRLSASSTGSTRSSQSA----SSLEVAGPGREPLELEVAV 460 PPP +P+ G L+ S+ +T + + S E P + E+A Sbjct: 611 -----PPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAA 665 Query: 461 EALARLQQGVSATVAHLLDLAGSAGATGSWRSPSEP 496 A +G + +A G+ GA W + P Sbjct: 666 CHPAAWSRGPAPPLA----FRGAPGAPLPWPPATGP 697 Score = 63.5 bits (153), Expect = 8e-10 Identities = 90/351 (25%), Positives = 123/351 (35%), Gaps = 64/351 (18%) Query: 76 PGPPATPAQPQP-GLHAPAPPASQYTPMLPNTYQ---PQPDSVYLVPTPSKAQQGLYQVP 131 P PA P+QP+P GL A PP Q TP + P S P+PS A Q Q P Sbjct: 263 PRAPAHPSQPKPKGLQALRPP--QVTPPRKDAAPALGPLSSSPLATPSPSAALQS--QAP 318 Query: 132 GPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVPPGPGGPAQDIYQVPPSAGMGHDI 191 P + P + T TP L PP P P Sbjct: 319 ---PTLPATPHSSSLTCQLATP----------LPLAPPSPSAP----------------- 348 Query: 192 YQVPPSMDTRSWEGTKPPAKVVVPTRVGQGYVYEAAQPEQDEYDIPRHLLAPGPQDIYDV 251 PS+ T PP++ T +G + + +P L+P Sbjct: 349 ----PSLQTLPSPPATPPSQAT--TSLGSPTL------QATHSFLPSPPLSPLATPPPQA 396 Query: 252 PPVRGLLPSQYGQEVYDTPPMA-VKGPNGRDP------LLEVYDVPPSVEKGLPPSNHHA 304 PP L P Q +PP++ + P+ + P LL+ PP P + A Sbjct: 397 PPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA 456 Query: 305 VYDVPPSVSKDVPDGPLLREETYDVPPAFAKAKPFDPARTPLVLAAPPPDSPPAEDVYDV 364 V PS + P L VPP+ + P P+ TP A PP +PP + + Sbjct: 457 SPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQ-LAKP 515 Query: 365 PPPAPDLYDVPPGLRRPGPGTLYDVPRERVLPPEVADGGVVDSGVYAVPPP 415 PP AP PP P P + P + P + + A PPP Sbjct: 516 PPQAPPALATPPLQALPSPPASF--PGQAPFSPSAS----LPMSPLATPPP 560 Score = 62.4 bits (150), Expect = 2e-09 Identities = 112/432 (25%), Positives = 145/432 (33%), Gaps = 58/432 (13%) Query: 76 PGPPATPAQPQPGLHAP-APPASQY-------TPMLPNTYQPQPDSVYLVPTPSKAQQGL 127 P P A PA P L AP +PPAS +P PN +V+L+ P Sbjct: 392 PPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNAL-----AVHLLQAPFS----- 441 Query: 128 YQVPGPSPQFQ---SPPAKQTSTFSKQTPHHPFPSPATDLYQVPPGPGGPAQDIYQVPPS 184 P PSP Q SPPA + S P PS A QVPP P PA PP Sbjct: 442 ---PPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP--PAS-----PPM 491 Query: 185 AGMGHDIYQVPPSMDTRSWEGTKPPAKVVVPTRVGQGYVYEAAQPEQDEYDIPRHLLAPG 244 + Q PP + + KPP + P + P P A Sbjct: 492 SPSATPPPQAPPPLAAPPLQLAKPPPQ-APPALATPPLQALPSPPASFPGQAPFSPSASL 550 Query: 245 PQDIYDVPPVRGLLPSQYGQEVYDTPPMAVKGPNGRDPLLEVYDVPPSVEKGLPPSNHHA 304 P PP + P + PP P + P P + G P A Sbjct: 551 PMSPLATPPPQA--PPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSG--PRLTLA 606 Query: 305 VYDVPPSVSKDVP----DGPLLREETYDVPPAFAKAKPFDPARTPLVLAAPPPDSPPAED 360 + PP P GP L + + + +D A+PPPD+ + Sbjct: 607 LAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDA----E 662 Query: 361 VYDVPPPAPDLYDVPPGLRRPGPGTLYDVPRERVLPPEVADGGVVDSGVYAVPPPAEREA 420 + P A PP R PG +P P ADG +Y P E Sbjct: 663 LAACHPAAWSRGPAPPLAFRGAPGA--PLPWPPATGPGSADGLCT---IYETEGP-ESAT 716 Query: 421 PAEGKRLSASSTGSTRSSQSASSLEVAGPGREPLELEVAVEALARLQQGVSATVAHLLD- 479 PA G L + T ++A+ R P + + L LQ V V HLL Sbjct: 717 PAPG-ALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASV---VQHLLSR 772 Query: 480 ---LAGSAGATG 488 LA + GA G Sbjct: 773 TLLLAAAEGAAG 784 Score = 31.2 bits (69), Expect = 4.4 Identities = 39/143 (27%), Positives = 54/143 (37%), Gaps = 17/143 (11%) Query: 368 APDLYDVPPGLRRPGPGTLYDVPRERVLPPEVADGGVVDSGVYAVPPPAEREAPAEGKRL 427 AP + G RR G P + A G V G+ P A P EG R Sbjct: 150 APKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEV--GLPRPAPSARPRPPTEGPRK 207 Query: 428 SASSTG---STRSSQSASSLEVAGPGREPLELEVAVEALARLQQGVSATVAHLLDLAGSA 484 S SS +T S +A AG G + + +S++ L A S Sbjct: 208 SVSSASEHSTTEPSPAARRRPSAGGGLQ-----------RPASRSLSSSATPLSSPARSG 256 Query: 485 -GATGSWRSPSEPQEPLVQDLQA 506 A G+ R+P+ P +P + LQA Sbjct: 257 PSARGTPRAPAHPSQPKPKGLQA 279 >gi|182765466 FCH and double SH3 domains 2 [Homo sapiens] Length = 740 Score = 69.7 bits (169), Expect = 1e-11 Identities = 51/164 (31%), Positives = 76/164 (46%), Gaps = 12/164 (7%) Query: 9 KALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNRLKILVGMYD 68 KALYD ++ DELSF +G I+ +L ++ Q DG+W +GR G+ P +LV Sbjct: 573 KALYDYEGQTDDELSFPEGAIIRILNKENQDDDGFWEGEFNGRIGVFP----SVLVEELS 628 Query: 69 KKPAGPGPGPPATPAQPQPGLHAPAPPASQYTPMLPNTYQPQPD---SVYLVPTPSKAQQ 125 G P P P HA PP Y P++ P PD S+Y +PS ++ Sbjct: 629 ASENGDTPWMREIQISPSPKPHASLPPLPLY-DQPPSSPYPSPDKRSSLYFPRSPSANEK 687 Query: 126 GLY-QVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVP 168 L+ + PG S + P +++ K P P P T ++ P Sbjct: 688 SLHAESPGFSQASRHTP---ETSYGKLRPVRAAPPPPTQNHRRP 728 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 69.7 bits (169), Expect = 1e-11 Identities = 108/394 (27%), Positives = 136/394 (34%), Gaps = 70/394 (17%) Query: 65 GMYDKKPAGPGPGPPATPAQPQPGLHAPAPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQ 124 G+ P G P ATP P+ GL P P + P P P P P+P A Sbjct: 1139 GLATPPPKGAPTTPAATPPSPKGGLATPPPKGA---PTTPAATPPSPKGGLATPSPKGAP 1195 Query: 125 QGLYQVPGPSPQ--FQSPPAKQTSTFSKQTPHHP-----FPSP---ATDLYQVPPGP-GG 173 P PSP+ +P K T TP P PSP T PP P GG Sbjct: 1196 TTPAATP-PSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGG 1254 Query: 174 PAQDIYQVPPSAGMGHDIYQVPPSMD----TRSWEGTKPPAKVVVPTRVGQGYVYEAAQP 229 PA PP G PPS+ T +G PA V P+ G A P Sbjct: 1255 PA-----TPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGG----PATSP 1305 Query: 230 EQDEYDIPRHLLAPGPQDIYDVPPVRGLLPSQYGQEVYDTPPMAVKGPNGRDPLLEVYDV 289 + P P P+ PP +G TPP AV P+ + Sbjct: 1306 PKGA-PTPPAATPPSPKGSPGTPPPKGA----------PTPP-AVTPPSPKGTPTLPATT 1353 Query: 290 PPSVEKGLPPSNHHAVYDVPPSVSKDVPDGPLLREETYDVPPAF--AKAKPFDPARTPLV 347 P S KG P + PP+ + GP + + PA K P PA PL Sbjct: 1354 PSS--KGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPL- 1410 Query: 348 LAAPPPDSPPAEDVY----------DVPPPAPDLYDVPPGLRRPGPGTLYDVPRERVLPP 397 P PA V D+ PPA V P + P T P+ P Sbjct: 1411 ----SPKKAPATPVTREGAATPSKGDLTPPA-----VTPVSLKKAPAT--SAPKGGPATP 1459 Query: 398 EVADGGVVDSGVYAVPPPAEREAPAEGKRLSASS 431 D + AV PP+ +E PA + ++SS Sbjct: 1460 SSKG----DPTLPAVTPPSPKEPPAPKQVATSSS 1489 Score = 63.9 bits (154), Expect = 6e-10 Identities = 111/452 (24%), Positives = 135/452 (29%), Gaps = 81/452 (17%) Query: 55 VPGNRLKILVGMYDKKPAGPGPGPPATPAQPQPGLHAPA-------PPASQYTPMLPN-- 105 +P N L G D P PP+ P P P PP TP + N Sbjct: 836 LPENSLSFQ-GSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLP 894 Query: 106 -----TYQPQPDSVYLVPTPSKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSP 160 P P + S + + P P SP K T TP P P Sbjct: 895 FPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGP 954 Query: 161 ATDLYQ--------VPPGP-GGPAQDIYQVPPSAGMGHDIYQVPPSMD----TRSWEGTK 207 AT + PP P GGPA P G PPS T S +G Sbjct: 955 ATPSPKWAPTPPAATPPSPKGGPA-----TPSPKGAPTPPAATPPSPKGGPATPSPKGAP 1009 Query: 208 PPAKVVVPTRVGQGYVYEAAQPEQDEYDIPRHLLAPGPQDIYDVPPVRGLLPSQYGQEVY 267 P V P+ G AA P P P P+ P+ P+ Sbjct: 1010 TPPAVTPPSPKGS----PAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPT------- 1058 Query: 268 DTPPMAVKGPNG--RDPLLEVYDVPPSV----EKGLPPSNHHAVYDVPPSVSKDVPDGPL 321 TP + P G P L+ PP+ KG P + +PP+ + P G L Sbjct: 1059 -TPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGL 1117 Query: 322 LREETYDVPPAFAKAKPFDPARTPLV----LAAPPPDSPPAEDVYDVPPPAPDLYDVPP- 376 PP K P PA TP LA PPP P P P L PP Sbjct: 1118 A------TPP--HKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPK 1169 Query: 377 ---------------GLRRPGPGTLYDVPRERVLPPEVADGGVVDSGVYAVPPPAEREAP 421 GL P P P PP G S A PA Sbjct: 1170 GAPTTPAATPPSPKGGLATPSPKGAPTTP--AATPPSPKGGLATPSPKGAPTTPAATPPS 1227 Query: 422 AEGKRLSASSTGSTRSSQSASSLEVAGPGREP 453 +G + S G+ + + GP P Sbjct: 1228 PKGGLATPSPKGAPTTPAATPPSPKGGPATPP 1259 Score = 62.4 bits (150), Expect = 2e-09 Identities = 105/401 (26%), Positives = 134/401 (33%), Gaps = 57/401 (14%) Query: 78 PPATPAQPQPGLHAPAPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQGLYQVPGPSPQ- 136 P ATP P+ GL P P + P P P P P P A P PSP+ Sbjct: 1129 PAATPPSPKGGLATPPPKGA---PTTPAATPPSPKGGLATPPPKGAPTTPAATP-PSPKG 1184 Query: 137 -FQSPPAKQTSTFSKQTPHHP-----FPSP---ATDLYQVPPGPGGPAQDIYQVPPSAGM 187 +P K T TP P PSP T PP P G P G Sbjct: 1185 GLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGG----LATPSPKGA 1240 Query: 188 GHDIYQVPPSMDTRSWEGTKPPAKVVVPTRVGQGYVYEAAQPEQDEYDI--PRHLLAPGP 245 PPS + T PP P AA P + + P H AP P Sbjct: 1241 PTTPAATPPS--PKGGPATPPPKGAPTP---------PAATPPSLKGGLATPPHKGAPNP 1289 Query: 246 QDIYDVPPVRGLLPSQYGQEVYDTPPMAV----KGPNGRDPLLEVYDVPPSVEKGLPPSN 301 + P G P+ + TPP A KG G P + PP+V P Sbjct: 1290 AVVTPPSPKGG--PATSPPKGAPTPPAATPPSPKGSPGTPP-PKGAPTPPAVTPPSPKGT 1346 Query: 302 HHAVYDVPPSVSKDVPDGPLLREETYDVPPAFAKAKPFDPARTPLVLAAPPPDSPPAEDV 361 P SK P P +E PPA + PA TP P P PA Sbjct: 1347 PTLPATTPS--SKGGPTTPSSKEG--PTPPAATPSHKGGPAMTP-----PSPKRGPAIPS 1397 Query: 362 YDVPPPAPDLYDVPPGLRRPGPGTLYDVPRERVLPPEVADGGVVDSGVYAVPPPAEREAP 421 P +P + + P + P T V RE P D AV P + ++AP Sbjct: 1398 PKGDPTSPAVIPLSP---KKAPAT--PVTREGAATPSKG-----DLTPPAVTPVSLKKAP 1447 Query: 422 AEGKRLSASSTGSTRSSQSASSLEVAGPGREPLELEVAVEA 462 A +T S++ + ++ P P +VA + Sbjct: 1448 ATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSS 1488 Score = 53.5 bits (127), Expect = 8e-07 Identities = 110/453 (24%), Positives = 150/453 (33%), Gaps = 90/453 (19%) Query: 71 PAGPGP-GPPATPAQPQPGLHAPAPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQGLYQ 129 PA P G P PA P P P T P P + P+ + Sbjct: 1456 PATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKE 1515 Query: 130 VPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVPPGPGGPAQDIYQVPPSAGMGH 189 VP + P A + SK+TP P A +PP P+ + P+ Sbjct: 1516 VPATPSSRRDPIAPTATLLSKKTPATLAPKEAL----IPPAMTVPSP---KKTPAIPTPK 1568 Query: 190 DIYQVPPSMDTRSWEGTKPPAKVVVPTRVGQGYVYEAAQPEQDEYDIPRHLLAPGPQDIY 249 + P S E + PPA V P+ Y+ A P E IP + +P P++ Sbjct: 1569 EAPATPSSK-----EASSPPA--VTPS------TYKGA-PSPKELLIPPAVTSPSPKEAP 1614 Query: 250 DVPPVRGLLPSQYGQEVYDTPPMAVKGPNGRDPLLEVYDVPPSVEKGLPPSNHHAVYDVP 309 P V TPP KGP P KG P S V Sbjct: 1615 TPPAV--------------TPPSPEKGPATPAP------------KGTPTSP-----PVT 1643 Query: 310 PSVSKDVPDGPL-LREETYDVPPAFAKAKPFDPARTPL--VLAAPPPDSPP--------- 357 PS KD P P + + P +K P T L VL AP P+S P Sbjct: 1644 PSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKG 1703 Query: 358 ---AEDVYDVPPPAPDLYDVPPGLRRPGPGTLYDVPRERVLPPEVADGGVVDSGVYAVPP 414 + PP PD P + G L V +LP + D G A Sbjct: 1704 PQTKKSSATSPPICPD-----PSAKNGSKGPLSTVAPAPLLPVQ-KDSSKTAKGKDASHS 1757 Query: 415 PAEREAPAEGKRLS-ASSTGSTRSSQSASSLEVAGPGREPLELEVA---VEALARLQQGV 470 P AP E K + ++ + S V+ P+ L +A V L QQ + Sbjct: 1758 PKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFL 1817 Query: 471 SATVAHLLDLAGSAGATGSWRSPSEPQEPLVQD 503 ++ +L+ SPS+P P +D Sbjct: 1818 PSSPGLVLE------------SPSKPLAPADED 1838 Score = 32.0 bits (71), Expect = 2.6 Identities = 84/380 (22%), Positives = 126/380 (33%), Gaps = 101/380 (26%) Query: 87 PGLHAPAPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQGLYQVPGPSPQFQSPPAKQTS 146 PG PA++ LP QPQ ++ L + + + PGP+ PA Q Sbjct: 2 PGEATETVPATEQE--LP---QPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQC 56 Query: 147 TFSKQTPHHPFPSPATDLYQVPPGPGGPAQDIYQVP-PSAGMGHDIYQVPPSMDTRSWEG 205 S PFPSP+T A +VP P + G T G Sbjct: 57 PLSAANQASPFPSPST-----------IASTPLEVPFPQSSSG-----------TALPLG 94 Query: 206 TKPPAKVVVPTRVGQGYVYEAAQPEQDEYDIPRHLLAPGPQDIYDVPPVRGLLPSQYGQE 265 T P A +P +G PP+ P+ Sbjct: 95 TAPEAPTFLPNLIG--------------------------------PPIS---PAALALA 119 Query: 266 VYDTPPMAVKGPNGRDPLLEVYDVPPSVEKGLPPSNHHAVYDVPPSVSKDVPDGPLLREE 325 P P+ PL V P SV+K PP++ Sbjct: 120 SPMIAPTLKGTPSSSAPLALVALAPHSVQKSSA---------FPPNLLTS---------- 160 Query: 326 TYDVPPAFAKAKPFDPARTPLVLAAPPPDSPPAEDVYDVPPPAPDLYDVPPGLRRPGPGT 385 PP+ A A+ + + + L+AP S P ++ VP ++ P G P P Sbjct: 161 ----PPSVAVAE----SGSVITLSAPIAPSEPKTNLNKVP---SEVVPNPKGTPSP-PCI 208 Query: 386 LYDVPRERVLPPEVADGGVVDSGVYAVP--PPAEREAPAEGKRLSASSTGSTRSSQSASS 443 + VP V P + SGV ++P P A A + + + S Q+ S Sbjct: 209 VSTVPYHCVTPM-----ASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGS 263 Query: 444 LEVAGPGREPLELEVAVEAL 463 L + GP P L ++ ++L Sbjct: 264 LSLKGPVSPPAALSLSTQSL 283 >gi|149158690 HLA-B associated transcript-2 [Homo sapiens] Length = 2157 Score = 67.4 bits (163), Expect = 5e-11 Identities = 118/450 (26%), Positives = 153/450 (34%), Gaps = 70/450 (15%) Query: 56 PGNRLKILVGMYDKKPAGPGPGPPATPAQPQPGLHAPAPPASQYTPMLPNTYQPQPDSVY 115 P RLK P+ P P PPA P + P AP PPAS TP Q Sbjct: 500 PDKRLKAEPAAPPAAPSTPAP-PPAVPKE-LPAPPAP-PPASAPTPETEPEEPAQAPPAQ 556 Query: 116 LVPTPSKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVPP------ 169 PTP A G S S + + S Q P P P +VPP Sbjct: 557 STPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPE---EVPPPTTPPV 613 Query: 170 ---GPGGPAQDIYQVPPSAGMGHDIYQ--VPPSMDTRSWEGTKPPAKVVVPTRVGQGYVY 224 P G + PPS G+G+ YQ +PP + E + + QG Sbjct: 614 PKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAP 673 Query: 225 EAAQPEQDEYDIPRHLLAPGPQDIYDVPPVRGLLPSQYGQEVYDTPPMAVKGPNGRDPLL 284 P + + P PQ PP + L P G+ PPM + R ++ Sbjct: 674 PTPVPPSPPQPVTLGAV-PAPQ--APPPPPKALYPGALGR----PPPMPPMNFDPRWMMI 726 Query: 285 EVYDVPPSVEKGLPPSNHHAVYDVPPSVSKDVPDGPLLRE---------ETYD------- 328 Y V P + +G PP + + PP V P G + RE E +D Sbjct: 727 PPY-VDPRLLQGRPPLDFY-----PPGVH---PSGLVPRERSDSGGSSSEPFDRHAPAML 777 Query: 329 ----VPPAFAK---------AKPFD--PARTPLVLAAPPPDSPPAEDVYDVPPPAPDLYD 373 PP K A P + P +PL AA D + VPPP P L Sbjct: 778 RERGTPPVDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLAS 837 Query: 374 VP--PGLRRPGPGTLYDVPRERVLPPEVADGGVVDSGVYAVPPPAEREAPAEGKRLSASS 431 P P PGP + P E P + D PP ++E P K +A Sbjct: 838 YPGFPENGAPGP-PISRFPLEEPGPRPLPWPPGSDEVAKIQTPPPKKEPP---KEETAQL 893 Query: 432 TGSTRSSQSASSLEVAGPGREPLELEVAVE 461 TG + A + G G P E E Sbjct: 894 TGPEAGRKPARGVGSGGQGPPPPRRESRTE 923 Score = 40.4 bits (93), Expect = 0.007 Identities = 83/361 (22%), Positives = 119/361 (32%), Gaps = 50/361 (13%) Query: 47 SLHGRQGIVPGNRLKILVGMYDKKPAGPGPGPPATPAQPQP-GLHAPAPPASQYTPM-LP 104 S G G PG R G DK+ + P P + P + +P GL P PP S L Sbjct: 1410 SSSGGGGGGPGGRTG--PGRGDKR-SWPSPKNRSRPPEERPPGLPLPPPPPSSSAVFRLD 1466 Query: 105 NTYQPQPDSVYLVPTPSKAQQGLYQVPGPSPQF-----QSPPAKQTSTFSKQTPHHPFPS 159 P + ++QG PG P+ Q+P ++ P Sbjct: 1467 QVIHSNPAGIQQALAQLSSRQGSVTAPGGHPRHKPGLPQAPQGPSPRPPTRYEPQRVNSG 1526 Query: 160 PATDLYQVPPGPGGPAQDIYQVPPSAGMGHDIYQVPPSMDTRSWEGTKPPAKVVVPTRVG 219 ++D + PGP V G D V P PP + P R Sbjct: 1527 LSSDPHFEEPGP--------MVRGVGGTPRDSAGVSPF----------PPKRRERPPRKP 1568 Query: 220 QGYVYEAAQPEQDEYDIPRHLLAPGPQDIYDVPPVRGLLPSQYGQEVYDTPPMAVKGPNG 279 + E+ P + PGPQ L P + + T + + P+ Sbjct: 1569 ELLQEESLPPPHSSGFLGSKPEGPGPQAESRDTGTEALTPHIWNRLHTATSRKSYR-PSS 1627 Query: 280 RDPLLEVYDVPPSVEKGLPPSNHHAVYDVPPSVSKDVPDGPLLREETYDVPPAFAKAKPF 339 +P +E P G S + D+ S V GP + + P K Sbjct: 1628 MEPWMEPLS-PFEDVAGTEMSQSDSGVDL--SGDSQVSSGPCSQRSS---PDGGLKGAAE 1681 Query: 340 DPARTP---LVLAAPPPDSPPAEDVYDVPPPAPDLYDVPPGLRRPGPGTLYDVPRERVLP 396 P + P L A P + PP + PPPAP G ++PRE+ LP Sbjct: 1682 GPPKRPGGSSPLNAVPCEGPPGSEPPRRPPPAPH------------DGDRKELPREQPLP 1729 Query: 397 P 397 P Sbjct: 1730 P 1730 Score = 40.0 bits (92), Expect = 0.009 Identities = 95/402 (23%), Positives = 128/402 (31%), Gaps = 102/402 (25%) Query: 80 ATPAQPQ-PGLHAPAPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQGL----YQVPGPS 134 A+P +PQ P P PP P P + +P + PT QGL YQ P Sbjct: 586 ASPVEPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLP- 644 Query: 135 PQFQSPPAKQTSTFSKQ-------------TPHHPFPSPATDLYQVPP--GPGGPAQDIY 179 P+FQ +Q +Q TP P P L VP P P + +Y Sbjct: 645 PRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPVPPSPPQPVTLGAVPAPQAPPPPPKALY 704 Query: 180 -----QVPPSAGMGHDI--YQVPPSMDTRSWEGTKP---------PAKVVVPTRVGQG-- 221 + PP M D +PP +D R +G P P+ +V R G Sbjct: 705 PGALGRPPPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFYPPGVHPSGLVPRERSDSGGS 764 Query: 222 -----------YVYEAAQPEQDEY-----DI-------PRHLLAPGPQ-----------D 247 + E P D D+ PR L +P Q + Sbjct: 765 SSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSE 824 Query: 248 IYDVPPVRGLLPSQYGQEVYDTP-------------PMAVKGPNGRDPLLEVYDVPPSVE 294 VPP L S G P P + P G D + ++ PP E Sbjct: 825 TPPVPPPPPYLASYPGFPENGAPGPPISRFPLEEPGPRPLPWPPGSDEVAKIQTPPPKKE 884 Query: 295 KGLPPSNHHAVYDVPPSVSKD---VPDG-----PLLREETYDV-----PPAFAKAKPFDP 341 PP A P + K V G P RE + P + + P + Sbjct: 885 ---PPKEETAQLTGPEAGRKPARGVGSGGQGPPPPRRESRTETRWGPRPGSSRRGIPPEE 941 Query: 342 ARTPLVLAAPPPDSPPAEDVYDVPPPAPDLYDVPPGLRRPGP 383 P A P PP V ++PP + D P +P P Sbjct: 942 PGAPPRRAGPIKKPPPPTKVEELPPKPLEQGDETPKPPKPDP 983 Score = 33.1 bits (74), Expect = 1.1 Identities = 101/421 (23%), Positives = 138/421 (32%), Gaps = 117/421 (27%) Query: 93 APPASQYTPMLPN---TYQPQP---DSVYLVPTPSKAQQGLY-------------QVPGP 133 A P S+ +LP+ + +PQ DS + VP PS + Q LY Q+ G Sbjct: 1792 AIPVSRDWELLPSAAASAEPQSKNLDSGHCVPEPSSSGQRLYPEVFYGSAGPSSSQISGG 1851 Query: 134 SPQFQSPPAKQTSTFSKQTPH-HPFPSPATDLYQVPPGPGGPAQDIYQVPPSAGMGHDIY 192 + Q P + F TP HP+ S LY +PPGP PPSA + + Sbjct: 1852 AMDSQLHP--NSGGFRPGTPSLHPYRSQP--LY-LPPGPA---------PPSALLS-GLA 1896 Query: 193 QVPPSMDTRSWEGTK----PPAKVVVPTRVGQGYVYEAA---QPEQDEYDIPRHLLAPGP 245 +D + + T+ P V+ P ++Y A P D + P P Sbjct: 1897 LKGQFLDFSTMQATELGKLPAGGVLYPP---PSFLYSPAFCPSPLPDTSLLQVRQDLPSP 1953 Query: 246 QDIYDVP----PVRGLLPSQYGQEVYDTPPMAVKGPNGRDPLLEVYDVPPSVEKGLPPSN 301 D Y P G LPS G + LL P V+ LP N Sbjct: 1954 SDFYSTPLQPGGQSGFLPS---------------GAPAQQMLL------PMVDSQLPVVN 1992 Query: 302 HHAVYDVPPSVSKDVPDGPLLREETYDVPPAFAKAKPFDPARTPLVLAAPPPDSPPAEDV 361 ++ PP PP + P PA P LA PP +P + Sbjct: 1993 FGSLPPAPPPA-----------------PPPLSLL-PVGPALQPPSLAVRPPPAPATRVL 2034 Query: 362 YDVPPPAP------DLYDV-----------------PPGLRRPGPGTLYDVPRERVLPPE 398 P P +L+ V P R P G + R+ Sbjct: 2035 PSPARPFPASLGRAELHPVELKPFQDYQKLSSNLGGPGSSRTPPTGRSFSGLNSRLKATP 2094 Query: 399 VADGGV-----VDSGVYAVPPPAEREAPAEGKRLS-ASSTGSTRSSQSASSLEVAGPGRE 452 GV VD A PP A R P +R G +R ++ S PG Sbjct: 2095 STYSGVFRTQRVDLYQQASPPDALRWIPKPWERTGPPPREGPSRRAEEPGSRGDKEPGLP 2154 Query: 453 P 453 P Sbjct: 2155 P 2155 Score = 32.0 bits (71), Expect = 2.6 Identities = 37/151 (24%), Positives = 55/151 (36%), Gaps = 18/151 (11%) Query: 39 GLDGWWLCSLHGRQGIVPGNRLKILVGMYDKKPAGPGPGPPATPAQP-----QPGLHAPA 93 G G+ +Q ++P ++ V + P P P PP P QP A Sbjct: 1965 GQSGFLPSGAPAQQMLLPMVDSQLPVVNFGSLPPAPPPAPPPLSLLPVGPALQPPSLAVR 2024 Query: 94 PPASQYTPMLPNTYQPQPDSV---YLVPTPSKAQQGLYQVP----GPSPQFQSPPAKQTS 146 PP + T +LP+ +P P S+ L P K Q ++ GP P + S Sbjct: 2025 PPPAPATRVLPSPARPFPASLGRAELHPVELKPFQDYQKLSSNLGGPGSSRTPPTGRSFS 2084 Query: 147 TFSKQTPHHP------FPSPATDLYQVPPGP 171 + + P F + DLYQ P Sbjct: 2085 GLNSRLKATPSTYSGVFRTQRVDLYQQASPP 2115 >gi|110349719 titin isoform N2-A [Homo sapiens] Length = 33423 Score = 67.0 bits (162), Expect = 7e-11 Identities = 94/369 (25%), Positives = 136/369 (36%), Gaps = 57/369 (15%) Query: 69 KKPAGPGPGPPATPAQPQPGLHAPAPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQGLY 128 KKP P P P P + P P PP + P +P T P+ V P K Sbjct: 10516 KKPEAPPPKVPEAPKEVVPEKKVPVPPPKK--PEVPPTKVPE---VPKAAVPEKKVPEAI 10570 Query: 129 QVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVPPGPGG--PAQDIYQVPPSAG 186 SP + P A + K+ P P P +VP P P + + PP Sbjct: 10571 PPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKP 10630 Query: 187 MGHDIYQVPPSMDTRSWEGTKPP--AKVVVP-TRVGQGYVYEAAQPEQDEYDIPRHL-LA 242 +VPP TK P KV VP +V + + P + ++ P + L Sbjct: 10631 ------EVPP---------TKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALE 10675 Query: 243 PGPQDIYDVP----PVRGLLPSQYGQEVYDTPPMAVKGPNGRDPLLEVYDVPPSV--EKG 296 P ++ + P P + +P + P + K P P ++V +VP V EK Sbjct: 10676 EPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKP--ELPPVKVPEVPKEVVPEKK 10733 Query: 297 LP---PSNHHAVYDVPPSVSKDVPDGPLLREETYDVPPAFAKAKPFDPARTPLVLAAPPP 353 +P P A PP+ +VP +E + A K PA+ P V P Sbjct: 10734 VPLVVPKKPEA----PPAKVPEVP-----KEVVPEKKVAVPKKPEVPPAKVPEVPKKPVL 10784 Query: 354 DSPPAEDVYD-VPPPAPDLYDVPPGLRRPGPGTLYDVPRERVLPPEVADGGVVDSGVYAV 412 + PA V + P P++Y+ P + P E + P E V + V Sbjct: 10785 EEKPAVPVPERAESPPPEVYEEPEEI----------APEEEIAPEEEKPVPVAEEEEPEV 10834 Query: 413 PPPAEREAP 421 PPPA E P Sbjct: 10835 PPPAVPEEP 10843 Score = 64.7 bits (156), Expect = 4e-10 Identities = 90/394 (22%), Positives = 143/394 (36%), Gaps = 53/394 (13%) Query: 68 DKKPAGPGPGPPATPAQPQPGLHAPAPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQGL 127 +KKP P P A P P P + ++P +P P V VP ++ Sbjct: 9961 EKKPV---PVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEE-- 10015 Query: 128 YQVPGPSPQ-FQSPPAKQTSTFSKQTPHHPFPSPATDLYQVPPG---------------P 171 +VP P P+ ++PPAK K P P PA + PP P Sbjct: 10016 -KVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKP 10074 Query: 172 GGPAQDIYQVPPSAGMGHDIYQVP---PSMDTRSWEGTKPPAKVVVPTRVGQGYVYEAAQ 228 + + PP + VP P + +E P + V+P E Sbjct: 10075 TPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPEEEEVLPEEEEVL 10134 Query: 229 PEQDEYDIPRHLLAPGPQDIYDVPPVRGLLPSQYG--------QEVYDTPPMAVKGPNGR 280 PE++E +P P ++ +VPP +P + EV P+ P + Sbjct: 10135 PEEEEV-LPEEEEIPPEEE--EVPPEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPVPEIK 10191 Query: 281 DPLLEVYDVPPSVEKGLP---PSNHHAVYD-----------VPPSVSKDVPDGPLLREET 326 + E V P E+ P P V + +P V+++ + P+ EE Sbjct: 10192 KKVTEKKVVIPKKEEAPPAKVPEVPKKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEI 10251 Query: 327 YDVPPAFAKAKPFDPARTPLVLAAPPPDSPPAEDVYDVPPPAPDLYDVPPGLRRPGPGTL 386 + PP+ + + P R P V+ P++P PPA +P + P P Sbjct: 10252 PEEPPSIEEVEEVAPPRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIPEE-KVPVPVQK 10310 Query: 387 YDVPRERV--LPPEVADGGVVDSGVYAVPPPAER 418 + P +V +P +V + V+ AVPP R Sbjct: 10311 KEAPPAKVPEVPKKVPEKKVLVPKKEAVPPAKGR 10344 Score = 47.0 bits (110), Expect = 8e-05 Identities = 96/430 (22%), Positives = 148/430 (34%), Gaps = 105/430 (24%) Query: 70 KPAGPGPGPPATPAQPQPGLHAPAPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQGLYQ 129 KP P P P P + P PA P + P+ V VP K + Sbjct: 10573 KPESPPPEVPEAPKEVVPEKKVPAAPPKK----------PEVTPVK-VPEAPKEVVPEKK 10621 Query: 130 VPGPSPQF-QSPPAKQTSTFSKQTPHHPFPSPATDLYQVPPGPGGPAQDIYQVPPSAGMG 188 VP P P+ + PP K P P +PP P P ++++ P + Sbjct: 10622 VPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEA------IPPKPESPPPEVFEEPEEVALE 10675 Query: 189 HDIYQVPPSMDTRSWEGTKPPAKVVVPTRVGQGYVYEAAQPEQDEYDIPR---------- 238 +V + + P K VP + V A +PE +P Sbjct: 10676 EPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVV--AKKPELPPVKVPEVPKEVVPEKK 10733 Query: 239 -HLLAPG------------PQDIY-----------DVPPVRGLLPSQYGQEVYDTPPMAV 274 L+ P P+++ +VPP + +P + V + P Sbjct: 10734 VPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAK--VPEVPKKPVLEEKPAVP 10791 Query: 275 KGPNGRDPLLEVYDVP----------PSVEKGLPPSNHHAVYDVPPSVSKD----VPDG- 319 P EVY+ P P EK +P + PP+V ++ +P+ Sbjct: 10792 VPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKK 10851 Query: 320 -PLLREETYDVP----PAFAKAKPFDPARTPLVLAAPPPDSPPAEDVYD----------- 363 P++++ P P KP R P PPP +PP EDV + Sbjct: 10852 VPVIKKPEAPPPKEPEPEKVIEKPKLKPRPP-----PPPPAPPKEDVKEKIFQLKAIPKK 10906 Query: 364 -VP--PPAPDLYDVPPGLRRPGPGTLYDVPRERVLP---PEVADGGVVDSGVYAVPPPAE 417 VP P P+ ++ P L+ PG + ++LP PE + V+ S + P E Sbjct: 10907 KVPEKPQVPEKVELTP-LKVPGG----EKKVRKLLPERKPEPKEEVVLKSVLR--KRPEE 10959 Query: 418 REAPAEGKRL 427 E E K+L Sbjct: 10960 EEPKVEPKKL 10969 Score = 43.9 bits (102), Expect = 7e-04 Identities = 74/323 (22%), Positives = 104/323 (32%), Gaps = 53/323 (16%) Query: 130 VPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVPPGPGGPAQDIYQV-PPSAGMG 188 +P P + P K+ + P P + +VP P P + +V PP + Sbjct: 10450 IPPKKPPTKVVPRKEPPA---KVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVP 10506 Query: 189 HDIYQVPPSMDTRSWEGTKPPAKVVVPTRVGQGYVYEAAQPEQDEYDIPRHLLAPGPQDI 248 VPP+ + PP KV PE + +P + P Sbjct: 10507 EKKVPVPPAKKPEA-----PPPKV----------------PEAPKEVVPEKKVPVPPPKK 10545 Query: 249 YDVPPVR-----------GLLPSQYGQEVYDTPPMAVKGPNGRDPLLEVYDVPPSVEKGL 297 +VPP + +P + PP + P P +V PP + Sbjct: 10546 PEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVT 10605 Query: 298 PPSNHHAVYDVPPSVSKDVPDGPLLREETYDVP--PAFAKAKPFDPARTPLVLAAPPPD- 354 P A +V P VP VP P A + P P +PPP+ Sbjct: 10606 PVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEV 10665 Query: 355 ----------SPPAEDVYDVPPPAPDLYDVPPGLRRPGPGTLYDVPRERVLP----PEVA 400 PPAE V + P AP VPP P V ++ LP PEV Sbjct: 10666 FEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVP 10725 Query: 401 DGGVVDSGVYAVPPPAEREAPAE 423 V + V V P PA+ Sbjct: 10726 KEVVPEKKVPLVVPKKPEAPPAK 10748 Score = 39.7 bits (91), Expect = 0.012 Identities = 61/234 (26%), Positives = 90/234 (38%), Gaps = 22/234 (9%) Query: 252 PPVRGLLPSQYGQEVYDTP-PMAVKGPNGRDPLLEVYDVPPSVEKGLPPSNHHAVYDVPP 310 P V L +EV P P V+ P + P + VP + P A PP Sbjct: 9286 PKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAA---PP 9342 Query: 311 SVSKDVPDGPLLREETYDVPPAFAKAKPFDPARTPLVLAAPPPDSPPAEDVYDVPPPAPD 370 V +VP P+ E+ +P AK K PA+ P V + P P Sbjct: 9343 KVP-EVPKKPVPEEK---IPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPA 9398 Query: 371 LYDVP----PGLRRPGPGTLYDVPRERVLPPEV--ADGGVVDSGVYAVPPPAEREAPAEG 424 + ++P P R+P P +VP PP+V V AVP P ++AP Sbjct: 9399 VPEIPKKKVPEERKPVPRKEEEVPP----PPKVPALPKKPVPEEKVAVPVPVAKKAPPPR 9454 Query: 425 KRLSASSTGSTRSSQSASSLEVAGPGR-EPLELEVAVE---ALARLQQGVSATV 474 +S + + + L A P R E EV+ E + + ++GVS +V Sbjct: 9455 AEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEWSYSEEEEGVSISV 9508 Score = 34.3 bits (77), Expect = 0.52 Identities = 36/133 (27%), Positives = 49/133 (36%), Gaps = 22/133 (16%) Query: 69 KKPAGPGPGPPATPAQPQPGLHAPAP-----PASQYTPMLPNT-YQPQPDSVYLVPTPSK 122 KK P P P P +P P P P PA+ P +P +P P+ VP K Sbjct: 9307 KKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAA--PPKVPEVPKKPVPEEKIPVPVAKK 9364 Query: 123 AQQGLYQVPG-------------PSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVPP 169 + +VP + + +SPP K+ P P P + +VPP Sbjct: 9365 KEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAVPEIPKKKVPEERKPVPRKE-EEVPP 9423 Query: 170 GPGGPAQDIYQVP 182 P PA VP Sbjct: 9424 PPKVPALPKKPVP 9436 Score = 33.9 bits (76), Expect = 0.67 Identities = 28/101 (27%), Positives = 38/101 (37%), Gaps = 8/101 (7%) Query: 74 PGPGPPATPAQPQPGLHAPAPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQGLYQVPGP 133 P PP P P+P +P PP+ L P P + +PS + + P P Sbjct: 250 PHKTPPRIP--PKPKSRSPTPPSIAAKAQLARQQSPSP----IRHSPSPVRH--VRAPTP 301 Query: 134 SPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVPPGPGGP 174 SP PA + ST ++ P T V GP P Sbjct: 302 SPVRSVSPAARISTSPIRSVRSPLLMRKTQASTVATGPEVP 342 Score = 33.9 bits (76), Expect = 0.67 Identities = 27/104 (25%), Positives = 33/104 (31%), Gaps = 18/104 (17%) Query: 70 KPAGPGPGPPATPAQPQPGLHAPAPPASQYTPMLPNT----YQPQPDSVYLVPTPSKAQQ 125 K P P P P +P P AP P + P P +P P+ VP P K Sbjct: 9280 KRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKE-- 9337 Query: 126 GLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVPP 169 P P+ P K P P P + PP Sbjct: 9338 -----PAAPPKVPEVP-------KKPVPEEKIPVPVAKKKEAPP 9369 Score = 33.5 bits (75), Expect = 0.88 Identities = 35/121 (28%), Positives = 46/121 (38%), Gaps = 11/121 (9%) Query: 307 DVPPSVSKDVPDGPLLREETYDVPPAFAKAKPFDPARTPLVLAAPPPDSPPAEDVYDVPP 366 +V P + VP+ P P K K PA+ P V P P + PP Sbjct: 9941 EVVPVIPVKVPEVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPP 10000 Query: 367 PAPDLYDVPPGLRRPGPGTLYDVPRERVLP------PEVADGGVVDSGVYAVPPPAEREA 420 PA VP ++P P VP + + PEV V + V VP P + EA Sbjct: 10001 PA----KVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKV-PVPAPKKVEA 10055 Query: 421 P 421 P Sbjct: 10056 P 10056 Score = 30.0 bits (66), Expect = 9.7 Identities = 25/109 (22%), Positives = 42/109 (38%), Gaps = 7/109 (6%) Query: 62 ILVGMYDKKPAGPGPG--PPATPAQPQPGLHAPAPPASQYTPMLPNTYQPQPDSVYLVPT 119 +L + K+P P P +P + P PP +P + + +P Sbjct: 10948 VLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERK----IPE 11003 Query: 120 PSKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVP 168 P+K + +P P+P+ + P + T K P P P+P VP Sbjct: 11004 PTKVPEIKPAIPLPAPEPKPKPEAEVKTI-KPPPVEPEPTPIAAPVTVP 11051 >gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo sapiens] Length = 1636 Score = 67.0 bits (162), Expect = 7e-11 Identities = 120/473 (25%), Positives = 157/473 (33%), Gaps = 97/473 (20%) Query: 76 PGPPATPAQPQPGLHAPAPPASQYTPMLPNTYQPQPD-----SVYLVPTPSKAQQGLYQV 130 PGP A P P P L+ PA YTP L + P S Y+ P+ GL Sbjct: 808 PGPHAMPVAPGPALY----PAPAYTPELGLVPRSSPQHGVVSSPYVGVGPAPPVAGLPSA 863 Query: 131 PGPSPQFQSPP---AKQTSTFSKQTPHHPFPSPATDLYQVPPGPGGPAQDIYQVPPSAGM 187 P PQF P A + +T + + P PS P P P + VPP Sbjct: 864 P--PPQFSGPELAMAVRPATTTVDSIQAPIPSHTAPRPNPTPAPPPPC---FPVPPP--- 915 Query: 188 GHDIYQVPPSMDTRSWEGTKP-PAKVVVPTRVGQGYVYEAAQPEQDEYDIPRHLLAPGPQ 246 Q P+ T +P PA+ + + G+ P+ + P A GPQ Sbjct: 916 -----QPLPTPYTYPAGAKQPIPAQHHFSSGIPAGFPAPRIGPQPQPHPQPHPSQAFGPQ 970 Query: 247 DIYDVPPVR----------GLLPSQYGQEVYDTPPMAVKGPNGRDPLLEVYDVPPSVEKG 296 P++ GLLP Q P + + P P L P + Sbjct: 971 PPQQPLPLQHPHLFPPQAPGLLPPQSPYPYAPQPGVLGQPP----PPLHTQLYPGPAQDP 1026 Query: 297 LPPSNHHAVYDVPPSVSKDVPDGPLLREETYDVPPAFAKAKPFDPARTPLVLAAPPPDSP 356 LP H P P PL Y P+ +P P PL + P Sbjct: 1027 LPA--HSGALPFPSPGPPQPPHPPL----AYGPAPS---TRPMGPQAAPLTIRGPSSAGQ 1077 Query: 357 PAEDVYDVPPPAPDLYDVPPGLRRPGPGTLYDVPRERVLPPEVADGGVVDSGVYAVPPPA 416 + VP PAP PGPG + PR PP A PPP Sbjct: 1078 STPSPHLVPSPAPS----------PGPGPV--PPR----PPA------------AEPPPC 1109 Query: 417 EREAPAEGKRLSASSTGSTRSSQSASSLEV--------AGPGREPLELEVA-------VE 461 R A LS+S +QS + A GR P L + E Sbjct: 1110 LRRGAAAADLLSSSPESQHGGTQSPGGGQPLLQPTKVDAAEGRRPQALRLIERDPYEHPE 1169 Query: 462 ALARLQQGVSATVAHLLDLAGSAGATGS-WRSPSEPQEPLVQDLQAAVAAVQS 513 L +LQQ + A L G GA + WR + QE + A+A S Sbjct: 1170 RLRQLQQELEAFRGQL----GDVGALDTVWRELQDAQEHDARGRSIAIARCYS 1218 Score = 49.3 bits (116), Expect = 2e-05 Identities = 63/241 (26%), Positives = 85/241 (35%), Gaps = 34/241 (14%) Query: 71 PAGPGPGPPATPAQPQPGLHAPAPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQGL--- 127 P+ P P TPA P P P P LP Y + +P G+ Sbjct: 892 PSHTAPRPNPTPAPPPPCFPVPPPQP------LPTPYTYPAGAKQPIPAQHHFSSGIPAG 945 Query: 128 YQVP--GPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVPPGPG-GPAQDIYQVPPS 184 + P GP PQ P + F Q P P P L+ P PG P Q Y P Sbjct: 946 FPAPRIGPQPQ-PHPQPHPSQAFGPQPPQQPLPLQHPHLFP-PQAPGLLPPQSPYPYAPQ 1003 Query: 185 AGMGHDIYQVPPSMDTRSWEGTKPPAKVVVPTRVGQGYVYEAAQPEQDEYDIPRHLLAP- 243 G+ + Q PP + T+ + G PA+ +P G + + P Q + + AP Sbjct: 1004 PGV---LGQPPPPLHTQLYPG---PAQDPLPAHSG-ALPFPSPGPPQPPHPPLAYGPAPS 1056 Query: 244 ----GPQDIYDVPPVRGLLPSQYGQEVYD----TPPMAVKGPNGRDPLLEVYDVPPSVEK 295 GPQ P+ PS GQ P GP P + PP + + Sbjct: 1057 TRPMGPQ----AAPLTIRGPSSAGQSTPSPHLVPSPAPSPGPGPVPPRPPAAEPPPCLRR 1112 Query: 296 G 296 G Sbjct: 1113 G 1113 Score = 41.2 bits (95), Expect = 0.004 Identities = 52/189 (27%), Positives = 64/189 (33%), Gaps = 32/189 (16%) Query: 67 YDKKPAGPGPGPPATPAQPQPGLHAPAPPASQYTPMLPNTYQPQPDSVYLV--PTPSKAQ 124 Y +P G PP Q PG PA P+ PQP L P PS Sbjct: 1000 YAPQPGVLGQPPPPLHTQLYPGPAQDPLPAHSGALPFPSPGPPQPPHPPLAYGPAPSTRP 1059 Query: 125 QGLYQVP----GPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVPPGPGGPAQDIYQ 180 G P GPS QS P+ H PSPA PGP P + Sbjct: 1060 MGPQAAPLTIRGPSSAGQSTPSP-----------HLVPSPAP---SPGPGPVPPRPPAAE 1105 Query: 181 VPPSAGMGHDIYQVPPSMDTRSWEGTKPPA---KVVVPTRVGQGYVYEAAQP------EQ 231 PP G + S GT+ P ++ PT+V E +P E+ Sbjct: 1106 PPPCLRRGAAAADLLSSSPESQHGGTQSPGGGQPLLQPTKVDAA---EGRRPQALRLIER 1162 Query: 232 DEYDIPRHL 240 D Y+ P L Sbjct: 1163 DPYEHPERL 1171 Score = 35.8 bits (81), Expect = 0.18 Identities = 58/221 (26%), Positives = 77/221 (34%), Gaps = 35/221 (15%) Query: 172 GGPAQDIYQVPPSAGMGHDIYQVPPSMDTRSWEGTK---PPAKVVVPTRVGQGYVYEAAQ 228 G P +++ +PP D+ P DT T PP+ P+ G G Y + Sbjct: 739 GDPPEELRSLPP------DMVAGPRLPDTFLGSATPLHFPPSPF--PSSTGPGPHYLSGP 790 Query: 229 PEQDEYDIPRHLL---APGPQDIYDVPPVRGLLPSQ-YGQEVYDTPPMAVKGPNGRDPLL 284 Y P L+ APGP + V P L P+ Y E+ P + + P + Sbjct: 791 LPPGTYSGPTQLIQPRAPGPHAM-PVAPGPALYPAPAYTPELGLVPRSSPQHGVVSSPYV 849 Query: 285 EVYDVPPSVEKGLPPSNHHAVYDVPPSVSKDVPDGPLLREETYDVPPAFAKAKPFDPART 344 V PP GLP + PP S GP E V PA Sbjct: 850 GVGPAPPVA--GLPSAP-------PPQFS-----GP---ELAMAVRPATTTVDSIQAPIP 892 Query: 345 PLVLAAPPPDSPPAEDVYDVPPPAP--DLYDVPPGLRRPGP 383 P P P + VPPP P Y P G ++P P Sbjct: 893 SHTAPRPNPTPAPPPPCFPVPPPQPLPTPYTYPAGAKQPIP 933 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 64.3 bits (155), Expect = 5e-10 Identities = 124/483 (25%), Positives = 159/483 (32%), Gaps = 99/483 (20%) Query: 72 AGPGPGPPATPAQPQPGLHAPAPPA---SQYTPML-------PNTYQPQPDSVYLVPTPS 121 A P P P +P+ P P+PPA SQ T L +++ P P L P Sbjct: 296 ATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPP 355 Query: 122 KAQQGLYQVP---GPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVP--PGPGGPAQ 176 +A L P PSP SPP +T S Q P+ + A L Q P P P P Q Sbjct: 356 QAPPALALPPLQAPPSPP-ASPPLSPLATPSPQAPN----ALAVHLLQAPFSPPPSPPVQ 410 Query: 177 DIYQVPPSAGMGHDI---YQVPPSMDTRSWEGTKPPAKVVVPTRVGQGYVYEAAQPEQDE 233 + P S + Q PPS+ PP +V A P Q Sbjct: 411 APFSPPASPPVSPSATPPSQAPPSL-------AAPPLQVPPSPPASPPMSPSATPPPQAP 463 Query: 234 YDI---PRHLLAPGPQDIYDVPPVRGLLPSQYGQEVYDTPPMAVKG-----PNGRDPLLE 285 + P L P PQ PP P Q +PP + G P+ P+ Sbjct: 464 PPLAAPPLQLAKPPPQ----APPALATPPLQ----ALPSPPASFPGQAPFSPSASLPMSP 515 Query: 286 VYDVPPSVEKGLPPSNHHAVYDVPPSVSKDVPDGPLLREETYDVPP-------------A 332 + PP PP + VPPS P P L+ P A Sbjct: 516 LATPPPQA----PPVLAAPLLQVPPS----PPASPTLQAPRRPPTPGPDTSVSGPRLTLA 567 Query: 333 FAKAKPFDPARTPLVLAAPPP------------------DSPPAEDVYDVPPPAPDLYDV 374 A P P+R+P + P DS P PPP +L Sbjct: 568 LAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAAC 627 Query: 375 PPGL--RRPGPGTLYDVPRERVLP-PEVADGGVVDS--GVYAVPPPAEREAPAEGKRLSA 429 P R P P + LP P G D +Y P E PA G L Sbjct: 628 HPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGP-ESATPAPG-ALDP 685 Query: 430 SSTGSTRSSQSASSLEVAGPGREPLELEVAVEALARLQQGVSATVAHLLD----LAGSAG 485 + T ++A+ R P + + L LQ V V HLL LA + G Sbjct: 686 GPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASV---VQHLLSRTLLLAAAEG 742 Query: 486 ATG 488 A G Sbjct: 743 AAG 745 Score = 60.8 bits (146), Expect = 5e-09 Identities = 86/356 (24%), Positives = 121/356 (33%), Gaps = 29/356 (8%) Query: 74 PGPGPPATPAQPQPGLHAPAPPASQYTPMLPN-TYQPQPDSVYLVPTPSKAQQGLYQVPG 132 P P P A P P G AS+++ P+ + +P + + P+ P Sbjct: 181 PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPL 240 Query: 133 PSPQFQSPPAKQTSTFSKQTPHHPF-PSPATDLYQVPPGPGGPAQDIYQVP---PSAGMG 188 SP P A+ T + P HP P P PP P +D S+ + Sbjct: 241 SSPARSGPSARGTP----RAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLA 296 Query: 189 HDIYQVPPSMDTRSWEGTKPPAKVVVPTRVGQGYVYEAAQPEQDEYDIP--RHLLAPGPQ 246 PPS T P P++ Q P L P PQ Sbjct: 297 TPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQ 356 Query: 247 DIYDVPPVRGLLPSQYGQEVYDTPPMA-VKGPNGRDP------LLEVYDVPPSVEKGLPP 299 PP L P Q +PP++ + P+ + P LL+ PP P Sbjct: 357 ----APPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAP 412 Query: 300 SNHHAVYDVPPSVSKDVPDGPLLREETYDVPPAFAKAKPFDPARTPLVLAAPPPDSPPAE 359 + A V PS + P L VPP+ + P P+ TP A PP +PP + Sbjct: 413 FSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQ 472 Query: 360 DVYDVPPPAPDLYDVPPGLRRPGPGTLYDVPRERVLPPEVADGGVVDSGVYAVPPP 415 + PP AP PP P P + P + P + + A PPP Sbjct: 473 -LAKPPPQAPPALATPPLQALPSPPASF--PGQAPFSPSAS----LPMSPLATPPP 521 Score = 39.7 bits (91), Expect = 0.012 Identities = 36/110 (32%), Positives = 41/110 (37%), Gaps = 10/110 (9%) Query: 71 PAGPGPGPPATPA-QPQPGLHAP----APPASQYTPML---PNTYQPQPDSVYLVPTPSK 122 PA P P ATP Q P L AP A P Q P L P P P + + P Sbjct: 447 PASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFS 506 Query: 123 AQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVPPGPG 172 L P +P Q+PP Q P P SP + PP PG Sbjct: 507 PSASLPMSPLATPPPQAPPVLAAPLL--QVPPSPPASPTLQAPRRPPTPG 554 Score = 31.2 bits (69), Expect = 4.4 Identities = 39/143 (27%), Positives = 54/143 (37%), Gaps = 17/143 (11%) Query: 368 APDLYDVPPGLRRPGPGTLYDVPRERVLPPEVADGGVVDSGVYAVPPPAEREAPAEGKRL 427 AP + G RR G P + A G V G+ P A P EG R Sbjct: 141 APKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEV--GLPRPAPSARPRPPTEGPRK 198 Query: 428 SASSTG---STRSSQSASSLEVAGPGREPLELEVAVEALARLQQGVSATVAHLLDLAGSA 484 S SS +T S +A AG G + + +S++ L A S Sbjct: 199 SVSSASEHSTTEPSPAARRRPSAGGGLQ-----------RPASRSLSSSATPLSSPARSG 247 Query: 485 -GATGSWRSPSEPQEPLVQDLQA 506 A G+ R+P+ P +P + LQA Sbjct: 248 PSARGTPRAPAHPSQPKPKGLQA 270 >gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] Length = 1012 Score = 63.9 bits (154), Expect = 6e-10 Identities = 101/411 (24%), Positives = 138/411 (33%), Gaps = 73/411 (17%) Query: 74 PGPGPPATPAQPQPGLHAPAPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQGLYQVPGP 133 P PP TP P PG P P A+ P T P+ PT + Q P Sbjct: 197 PSSAPPGTPQLPTPG---PTPSATAVPPQGSPTASQAPNQPQ-APTAPVPHTHIQQAPAL 252 Query: 134 SPQFQSPPAKQTSTFSKQTPHHP-FPSPATDLYQVPPGPGGPAQDIYQVPPSAGMG---- 188 PQ PP+ PH P PSP L + G P+ + PP G G Sbjct: 253 HPQ--RPPS----------PHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGP 300 Query: 189 ----------HDIYQVPPSMDTRSWEGTKP----PAKVVVPTRVGQGYVYEAAQPEQDEY 234 H P + ++ +G P PA T + A Q +Q Sbjct: 301 HSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPR 360 Query: 235 DIPRHLLAPGPQDIYDV-PPVRGLLPSQYGQEVYDTPPMAVKGPNGRDPLLEVYDVPP-- 291 + P L P P + + PP +P + + PP +G P ++PP Sbjct: 361 EQP---LPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHL----SGPSPFSMNANLPPPP 413 Query: 292 ------SVEKGLPPSNHHAVYDVPPSVSKDVPDGP-----LLREETYDVPPA-------- 332 S+ PPS H + P S+ +P P L + + PPA Sbjct: 414 ALKPLSSLSTHHPPSAHPPPLQLMPQ-SQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLH 472 Query: 333 -FAKAKPFDPARTPLVLAAPPPDSPPAEDVYDVPPPAPDLYDVPPGLRRPGPGTLYDVPR 391 A PF A+ P V PPP +PP PP P PP G Sbjct: 473 QVAPQPPF--AQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGS 530 Query: 392 ERVLPP-EVADGGVVDSGVYAVPPPAEREAPAEGKRLSASSTGSTRSSQSA 441 LP ++ + + D+ PPP R E + S +SQSA Sbjct: 531 SCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPS----HASQSA 577 Score = 60.5 bits (145), Expect = 7e-09 Identities = 83/325 (25%), Positives = 113/325 (34%), Gaps = 46/325 (14%) Query: 70 KPAGPGPGPPATPAQPQPGLHAPAPP---ASQYTPMLPNTYQPQPDSVYLVPTPSKAQQG 126 +P G P+ P+ QP LH PP + Q P+L + PQP + P +A QG Sbjct: 273 QPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGL-----PPQASQG 327 Query: 127 LYQVP-GPSPQFQSP------PAKQTSTFSKQTP-HHPFPSPATDLYQVPPGPGGPAQDI 178 Q P G SP P PA Q++ S+Q P P P + + P P P I Sbjct: 328 --QAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTP---I 382 Query: 179 YQVPPSAGMGHDIYQVPPSMDTRSWEGTKPPAKVVVPTRVGQGYVYEAAQP------EQD 232 Q+P H + PS S PP + P + +A P Q Sbjct: 383 PQLPAPQAHKHPPHLSGPS--PFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQS 440 Query: 233 EYDIPRHLLAPGPQDIYDVPPVRGLLPSQYGQEVYDTPPMAVKG--PNGRDPLLEVYDVP 290 + PG ++PP P +V PP A P G P+ P Sbjct: 441 QPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPI-----TP 495 Query: 291 PSVEKGLPPSNHHAVYDVPPSVSKDVPDGPLLREETYDVPPAFAKAKPFDPARTPLVLAA 350 P+ P PP G + + +P K + D A P + Sbjct: 496 PTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEP---ES 552 Query: 351 PPPDSPPAEDVYDVPPPAPDLYDVP 375 PPP PP P P P + D P Sbjct: 553 PPP--PPRS-----PSPEPTVVDTP 570 Score = 58.2 bits (139), Expect = 3e-08 Identities = 102/403 (25%), Positives = 138/403 (34%), Gaps = 55/403 (13%) Query: 100 TPMLPNTYQPQPDSVYLVPTPSKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPS 159 +P +P+ + DS S AQQ + Q P+ Q + S+ TP P P Sbjct: 158 SPSIPSPQDNESDS------DSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPG 211 Query: 160 PATDLYQVPPGPGGPAQDIYQVP--PSAGMGHDIYQVPPSMDTRSWEGTKPPAKVVVPTR 217 P VPP A P P+A + H Q P++ + PP P Sbjct: 212 PTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPH-PSPHP 270 Query: 218 VGQGYVYEAAQPEQDEYDIP---------RHLLAPGPQDIYDVPPVRGLLPSQ--YGQEV 266 Q A QP + P H L GP + PP LP Q GQ Sbjct: 271 PLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAP 330 Query: 267 YDTPPMA------VKGPNGRDPLLEVYDVPPSVEKGLPPSNHHAVYDVPPSVSKDVPDGP 320 T P A ++ P + L P E+ LPP+ + PP + P Sbjct: 331 LGTSPAAAYPHTSLQLPASQSAL---QSQQPPREQPLPPAPLAMPHIKPPPTT---PIPQ 384 Query: 321 LLREETYDVPPAFAKAKPFD--------PARTPLVLAA---PPPDSPPAEDVYDVPPPAP 369 L + + PP + PF PA PL + PP PP + P P Sbjct: 385 LPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLP 444 Query: 370 DLYDVPPGLRR-----PGPGTLYDVPRERVLP-PEVADGGVVDSGVYAVPPPA--EREAP 421 PPGL + P P + +V P P A V G + PP P Sbjct: 445 SSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTP 504 Query: 422 AEGKRLSASSTGSTRSSQSASSLEVAGPGREPL-ELEVAVEAL 463 G SA S +AS +AG PL +++ EAL Sbjct: 505 PAGPGTSAQ---PPCSGAAASGGSIAGGSSCPLPTVQIKEEAL 544 >gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 63.9 bits (154), Expect = 6e-10 Identities = 101/411 (24%), Positives = 138/411 (33%), Gaps = 73/411 (17%) Query: 74 PGPGPPATPAQPQPGLHAPAPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQGLYQVPGP 133 P PP TP P PG P P A+ P T P+ PT + Q P Sbjct: 751 PSSAPPGTPQLPTPG---PTPSATAVPPQGSPTASQAPNQPQ-APTAPVPHTHIQQAPAL 806 Query: 134 SPQFQSPPAKQTSTFSKQTPHHP-FPSPATDLYQVPPGPGGPAQDIYQVPPSAGMG---- 188 PQ PP+ PH P PSP L + G P+ + PP G G Sbjct: 807 HPQ--RPPS----------PHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGP 854 Query: 189 ----------HDIYQVPPSMDTRSWEGTKP----PAKVVVPTRVGQGYVYEAAQPEQDEY 234 H P + ++ +G P PA T + A Q +Q Sbjct: 855 HSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPR 914 Query: 235 DIPRHLLAPGPQDIYDV-PPVRGLLPSQYGQEVYDTPPMAVKGPNGRDPLLEVYDVPP-- 291 + P L P P + + PP +P + + PP +G P ++PP Sbjct: 915 EQP---LPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHL----SGPSPFSMNANLPPPP 967 Query: 292 ------SVEKGLPPSNHHAVYDVPPSVSKDVPDGP-----LLREETYDVPPA-------- 332 S+ PPS H + P S+ +P P L + + PPA Sbjct: 968 ALKPLSSLSTHHPPSAHPPPLQLMPQ-SQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLH 1026 Query: 333 -FAKAKPFDPARTPLVLAAPPPDSPPAEDVYDVPPPAPDLYDVPPGLRRPGPGTLYDVPR 391 A PF A+ P V PPP +PP PP P PP G Sbjct: 1027 QVAPQPPF--AQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGS 1084 Query: 392 ERVLPP-EVADGGVVDSGVYAVPPPAEREAPAEGKRLSASSTGSTRSSQSA 441 LP ++ + + D+ PPP R E + S +SQSA Sbjct: 1085 SCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPS----HASQSA 1131 Score = 60.5 bits (145), Expect = 7e-09 Identities = 83/325 (25%), Positives = 113/325 (34%), Gaps = 46/325 (14%) Query: 70 KPAGPGPGPPATPAQPQPGLHAPAPP---ASQYTPMLPNTYQPQPDSVYLVPTPSKAQQG 126 +P G P+ P+ QP LH PP + Q P+L + PQP + P +A QG Sbjct: 827 QPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGL-----PPQASQG 881 Query: 127 LYQVP-GPSPQFQSP------PAKQTSTFSKQTP-HHPFPSPATDLYQVPPGPGGPAQDI 178 Q P G SP P PA Q++ S+Q P P P + + P P P I Sbjct: 882 --QAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTP---I 936 Query: 179 YQVPPSAGMGHDIYQVPPSMDTRSWEGTKPPAKVVVPTRVGQGYVYEAAQP------EQD 232 Q+P H + PS S PP + P + +A P Q Sbjct: 937 PQLPAPQAHKHPPHLSGPS--PFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQS 994 Query: 233 EYDIPRHLLAPGPQDIYDVPPVRGLLPSQYGQEVYDTPPMAVKG--PNGRDPLLEVYDVP 290 + PG ++PP P +V PP A P G P+ P Sbjct: 995 QPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPI-----TP 1049 Query: 291 PSVEKGLPPSNHHAVYDVPPSVSKDVPDGPLLREETYDVPPAFAKAKPFDPARTPLVLAA 350 P+ P PP G + + +P K + D A P + Sbjct: 1050 PTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEP---ES 1106 Query: 351 PPPDSPPAEDVYDVPPPAPDLYDVP 375 PPP PP P P P + D P Sbjct: 1107 PPP--PPRS-----PSPEPTVVDTP 1124 Score = 58.2 bits (139), Expect = 3e-08 Identities = 102/403 (25%), Positives = 138/403 (34%), Gaps = 55/403 (13%) Query: 100 TPMLPNTYQPQPDSVYLVPTPSKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPS 159 +P +P+ + DS S AQQ + Q P+ Q + S+ TP P P Sbjct: 712 SPSIPSPQDNESDS------DSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPG 765 Query: 160 PATDLYQVPPGPGGPAQDIYQVP--PSAGMGHDIYQVPPSMDTRSWEGTKPPAKVVVPTR 217 P VPP A P P+A + H Q P++ + PP P Sbjct: 766 PTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPH-PSPHP 824 Query: 218 VGQGYVYEAAQPEQDEYDIP---------RHLLAPGPQDIYDVPPVRGLLPSQ--YGQEV 266 Q A QP + P H L GP + PP LP Q GQ Sbjct: 825 PLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAP 884 Query: 267 YDTPPMA------VKGPNGRDPLLEVYDVPPSVEKGLPPSNHHAVYDVPPSVSKDVPDGP 320 T P A ++ P + L P E+ LPP+ + PP + P Sbjct: 885 LGTSPAAAYPHTSLQLPASQSAL---QSQQPPREQPLPPAPLAMPHIKPPPTT---PIPQ 938 Query: 321 LLREETYDVPPAFAKAKPFD--------PARTPLVLAA---PPPDSPPAEDVYDVPPPAP 369 L + + PP + PF PA PL + PP PP + P P Sbjct: 939 LPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLP 998 Query: 370 DLYDVPPGLRR-----PGPGTLYDVPRERVLP-PEVADGGVVDSGVYAVPPPA--EREAP 421 PPGL + P P + +V P P A V G + PP P Sbjct: 999 SSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTP 1058 Query: 422 AEGKRLSASSTGSTRSSQSASSLEVAGPGREPL-ELEVAVEAL 463 G SA S +AS +AG PL +++ EAL Sbjct: 1059 PAGPGTSAQ---PPCSGAAASGGSIAGGSSCPLPTVQIKEEAL 1098 >gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 63.9 bits (154), Expect = 6e-10 Identities = 101/411 (24%), Positives = 138/411 (33%), Gaps = 73/411 (17%) Query: 74 PGPGPPATPAQPQPGLHAPAPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQGLYQVPGP 133 P PP TP P PG P P A+ P T P+ PT + Q P Sbjct: 751 PSSAPPGTPQLPTPG---PTPSATAVPPQGSPTASQAPNQPQ-APTAPVPHTHIQQAPAL 806 Query: 134 SPQFQSPPAKQTSTFSKQTPHHP-FPSPATDLYQVPPGPGGPAQDIYQVPPSAGMG---- 188 PQ PP+ PH P PSP L + G P+ + PP G G Sbjct: 807 HPQ--RPPS----------PHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGP 854 Query: 189 ----------HDIYQVPPSMDTRSWEGTKP----PAKVVVPTRVGQGYVYEAAQPEQDEY 234 H P + ++ +G P PA T + A Q +Q Sbjct: 855 HSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPR 914 Query: 235 DIPRHLLAPGPQDIYDV-PPVRGLLPSQYGQEVYDTPPMAVKGPNGRDPLLEVYDVPP-- 291 + P L P P + + PP +P + + PP +G P ++PP Sbjct: 915 EQP---LPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHL----SGPSPFSMNANLPPPP 967 Query: 292 ------SVEKGLPPSNHHAVYDVPPSVSKDVPDGP-----LLREETYDVPPA-------- 332 S+ PPS H + P S+ +P P L + + PPA Sbjct: 968 ALKPLSSLSTHHPPSAHPPPLQLMPQ-SQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLH 1026 Query: 333 -FAKAKPFDPARTPLVLAAPPPDSPPAEDVYDVPPPAPDLYDVPPGLRRPGPGTLYDVPR 391 A PF A+ P V PPP +PP PP P PP G Sbjct: 1027 QVAPQPPF--AQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGS 1084 Query: 392 ERVLPP-EVADGGVVDSGVYAVPPPAEREAPAEGKRLSASSTGSTRSSQSA 441 LP ++ + + D+ PPP R E + S +SQSA Sbjct: 1085 SCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPS----HASQSA 1131 Score = 60.5 bits (145), Expect = 7e-09 Identities = 83/325 (25%), Positives = 113/325 (34%), Gaps = 46/325 (14%) Query: 70 KPAGPGPGPPATPAQPQPGLHAPAPP---ASQYTPMLPNTYQPQPDSVYLVPTPSKAQQG 126 +P G P+ P+ QP LH PP + Q P+L + PQP + P +A QG Sbjct: 827 QPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGL-----PPQASQG 881 Query: 127 LYQVP-GPSPQFQSP------PAKQTSTFSKQTP-HHPFPSPATDLYQVPPGPGGPAQDI 178 Q P G SP P PA Q++ S+Q P P P + + P P P I Sbjct: 882 --QAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTP---I 936 Query: 179 YQVPPSAGMGHDIYQVPPSMDTRSWEGTKPPAKVVVPTRVGQGYVYEAAQP------EQD 232 Q+P H + PS S PP + P + +A P Q Sbjct: 937 PQLPAPQAHKHPPHLSGPS--PFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQS 994 Query: 233 EYDIPRHLLAPGPQDIYDVPPVRGLLPSQYGQEVYDTPPMAVKG--PNGRDPLLEVYDVP 290 + PG ++PP P +V PP A P G P+ P Sbjct: 995 QPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPI-----TP 1049 Query: 291 PSVEKGLPPSNHHAVYDVPPSVSKDVPDGPLLREETYDVPPAFAKAKPFDPARTPLVLAA 350 P+ P PP G + + +P K + D A P + Sbjct: 1050 PTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEP---ES 1106 Query: 351 PPPDSPPAEDVYDVPPPAPDLYDVP 375 PPP PP P P P + D P Sbjct: 1107 PPP--PPRS-----PSPEPTVVDTP 1124 Score = 58.2 bits (139), Expect = 3e-08 Identities = 102/403 (25%), Positives = 138/403 (34%), Gaps = 55/403 (13%) Query: 100 TPMLPNTYQPQPDSVYLVPTPSKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPS 159 +P +P+ + DS S AQQ + Q P+ Q + S+ TP P P Sbjct: 712 SPSIPSPQDNESDS------DSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPG 765 Query: 160 PATDLYQVPPGPGGPAQDIYQVP--PSAGMGHDIYQVPPSMDTRSWEGTKPPAKVVVPTR 217 P VPP A P P+A + H Q P++ + PP P Sbjct: 766 PTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPH-PSPHP 824 Query: 218 VGQGYVYEAAQPEQDEYDIP---------RHLLAPGPQDIYDVPPVRGLLPSQ--YGQEV 266 Q A QP + P H L GP + PP LP Q GQ Sbjct: 825 PLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAP 884 Query: 267 YDTPPMA------VKGPNGRDPLLEVYDVPPSVEKGLPPSNHHAVYDVPPSVSKDVPDGP 320 T P A ++ P + L P E+ LPP+ + PP + P Sbjct: 885 LGTSPAAAYPHTSLQLPASQSAL---QSQQPPREQPLPPAPLAMPHIKPPPTT---PIPQ 938 Query: 321 LLREETYDVPPAFAKAKPFD--------PARTPLVLAA---PPPDSPPAEDVYDVPPPAP 369 L + + PP + PF PA PL + PP PP + P P Sbjct: 939 LPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLP 998 Query: 370 DLYDVPPGLRR-----PGPGTLYDVPRERVLP-PEVADGGVVDSGVYAVPPPA--EREAP 421 PPGL + P P + +V P P A V G + PP P Sbjct: 999 SSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTP 1058 Query: 422 AEGKRLSASSTGSTRSSQSASSLEVAGPGREPL-ELEVAVEAL 463 G SA S +AS +AG PL +++ EAL Sbjct: 1059 PAGPGTSAQ---PPCSGAAASGGSIAGGSSCPLPTVQIKEEAL 1098 >gi|116284392 mucin 2 precursor [Homo sapiens] Length = 5179 Score = 63.5 bits (153), Expect = 8e-10 Identities = 83/386 (21%), Positives = 106/386 (27%), Gaps = 62/386 (16%) Query: 71 PAGPGPGPPATPAQPQPGLHAPAPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQGLYQV 130 P P PP T P P+PP + T P T P S P P+ Sbjct: 1417 PPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTT 1476 Query: 131 PGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVPPG----------PGGPAQDIYQ 180 P P SPP T+T P PSP T PP P P Sbjct: 1477 PSPPTTTPSPPTTTTTT----PPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTT 1532 Query: 181 VPPSAGMGHDIYQVPPSMDTRSWEGTKPPAKVVVPTRVGQGYVYEAAQPEQDEYDIPRHL 240 PP+ PS T + + PT P P Sbjct: 1533 PPPT---------TTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTT 1583 Query: 241 LAPGPQDIYDVPPVRGLLPSQYGQEVYDTPPMAVKGPNGRDPLLEVYDVPPSVEKGLPPS 300 P P I P PS PP P P+ PP+ LPP+ Sbjct: 1584 TTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPI-----TPPTSTTTLPPT 1638 Query: 301 NHHAVYDVPPSVSKDVPDGPLLREETYDVPPAFAKAKPFDPARTPLV--LAAPPPDSPPA 358 + PP + P PP + P +P + PPP + P+ Sbjct: 1639 TTPS----PPPTTTTTP------------PPTTTPSPPTTTTPSPPITTTTTPPPTTTPS 1682 Query: 359 EDVYDVP-PPAPDLYDVPPGLRRPGPGTLYDVPRERVLPPEVADGGVVDSGVYAVPPPAE 417 + P PP + P P T P P PPP Sbjct: 1683 SPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPS---------------PPPTT 1727 Query: 418 REAPAEGKRLSASSTGSTRSSQSASS 443 P+ S +T T + +S Sbjct: 1728 MTTPSPTTTPSPPTTTMTTLPPTTTS 1753 Score = 35.8 bits (81), Expect = 0.18 Identities = 31/117 (26%), Positives = 40/117 (34%), Gaps = 7/117 (5%) Query: 71 PAGPGPGPPATPAQPQPGLHAPAPPASQYTPMLPNTYQPQPDSVYLV---PTPSKAQQGL 127 P P PP T P P + P TP P T P P + + PT + + Sbjct: 1652 PPTTTPSPPTTTT-PSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPIT 1710 Query: 128 YQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVPPGPGGPAQDIYQVPPS 184 S SPP +T S T P P T + +PP +PPS Sbjct: 1711 TTTTPSSTTTPSPPPTTMTTPSPTTTPSP---PTTTMTTLPPTTTSSPLTTTPLPPS 1764 Score = 30.8 bits (68), Expect = 5.7 Identities = 23/87 (26%), Positives = 29/87 (33%), Gaps = 7/87 (8%) Query: 76 PGPPATPAQP------QPGLHAPAPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQGLYQ 129 P P TP+ P P+PP + T P T P + P+ L Sbjct: 1699 PSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTT 1758 Query: 130 VPGPSPQFQSPPAKQTSTFSKQTPHHP 156 P P P P ST + TP P Sbjct: 1759 TPLP-PSITPPTFSPFSTTTPTTPCVP 1784 >gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo sapiens] Length = 1560 Score = 63.5 bits (153), Expect = 8e-10 Identities = 86/352 (24%), Positives = 113/352 (32%), Gaps = 63/352 (17%) Query: 72 AGPGPGPPATPAQPQPGLHAPAPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQGLYQVP 131 A G P QP P APPA TP+ QPQ PTP A P Sbjct: 610 AATGEAAPVLTVQPAP----QAPPAVS-TPLPLGLQQPQAQQPPQAPTPQAAAPPQATTP 664 Query: 132 GPSPQFQSPPAK----------------------------QTSTFSKQTPHHPFPSPATD 163 PSP S P K S + PH PA+ Sbjct: 665 QPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPH--LSVPASV 722 Query: 164 LYQVPPGPGGPAQDIYQVPP---SAGMGHDIYQVPPSMDTRSWEGTKPPAKVVVPTRVGQ 220 + PP PAQD P AG+G P + D+++ P P + G Sbjct: 723 IVSAPP----PAQDPAPATPVAKGAGLG------PQAPDSQASPAPAPQIPAAAPLK-GP 771 Query: 221 GYVYEAAQPEQDEYDIPRHLLAPGPQDIYDVPPVRGLLPSQYGQEVYDTPPMAVKGPNGR 280 G + P Q HL +P P PP R P + + P P Sbjct: 772 GPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSR---PQSVSRPPSEPPLHPCPPPQAP 828 Query: 281 DPLLEVYDVPPSVEKGLPPSNHHAVYDVPPS----VSKDVPDGPLLREETYDVPPAFAKA 336 L ++ + + P SN PP P+GPL +PP+ + Sbjct: 829 PTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPL--PPAPHLPPSSTSS 886 Query: 337 KPFDPARTPLVLAAPPPDS-----PPAEDVYDVPPPAPDLYDVPPGLRRPGP 383 + T L AP P PP++ + P P P L+ VP P P Sbjct: 887 AVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPP 938 Score = 51.6 bits (122), Expect = 3e-06 Identities = 85/371 (22%), Positives = 125/371 (33%), Gaps = 49/371 (13%) Query: 124 QQGLYQVP-----GPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVPPG---PGGPA 175 Q L+Q+P G P QS PA + P A + P G P PA Sbjct: 551 QPALFQMPVSLAAGSLPT-QSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPA 609 Query: 176 QDIYQVPPSAGMGHDIYQVPPSMDTRSWEGTKPPAKVVVPTRVGQGYVYEAAQPEQDEYD 235 + P + Q PP++ T G + P P Q +AA P Q Sbjct: 610 AATGEAAPVLTV-QPAPQAPPAVSTPLPLGLQQPQAQQPP----QAPTPQAAAPPQATTP 664 Query: 236 IPRHLLAPGPQDIY-DVPP------------VRGLLPSQYGQEVYDTPPMAVKGPNGRDP 282 P LA P+ I PP ++ LP + Q+ P++ +GP+ P Sbjct: 665 QPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQ-----PLSAEGPHLSVP 719 Query: 283 LLEVYDVPPS---------VEKGLPPSNHHAVYDVPPSVSKDVPDGPLLREETYDVPPAF 333 + PP V KG P+ + +P L+ P+ Sbjct: 720 ASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSL 779 Query: 334 AKAKPF-DPARTPLVLAAPPPDSPPAE-DVYDVPPPAPDLYDVPPGLRRPGPGTLYDVPR 391 P D P PP PP+ PP P L+ PP P ++ + Sbjct: 780 PHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQN 839 Query: 392 ERVLPPEVADGGVVDSGVYAVPPPAEREAPAEG-----KRLSASSTGSTRSSQSASSLEV 446 + +PP ++ G PP + P EG L SST S +S S +S + Sbjct: 840 QLGVPPPASNPAPTAPGP-PQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRL 898 Query: 447 AGPGREPLELE 457 P +L+ Sbjct: 899 PAPTPSDFQLQ 909 Score = 48.9 bits (115), Expect = 2e-05 Identities = 88/327 (26%), Positives = 112/327 (34%), Gaps = 73/327 (22%) Query: 70 KPAGPGPGPPATPAQPQPGLHAPAP-----PASQYTPMLPNTYQPQPDSVYLVPTPSKAQ 124 K AG GP P + A P P PA P +P LP+ P DS +L PS Sbjct: 741 KGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPH-QAPLGDSPHL---PS--- 793 Query: 125 QGLYQVPGPSPQFQSPPAKQTSTF--SKQTPHHPFPSPATDLYQVPPGPGG--PAQDIYQ 180 P P+ PP++ S + P HP P P Q PP G Q+ Sbjct: 794 ------PHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPP-----QAPPTLPGIFVIQNQLG 842 Query: 181 VPPSAGMGHDIYQVPPSMDTRSW----EGTKPPAKVVVPTRVGQGYVYEAAQPEQDEYDI 236 VPP A PP R EG PPA + P+ + + Sbjct: 843 VPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSS--------ET 894 Query: 237 PRHLLAPGPQDIYDVPPVRGLLPSQYGQEVYDTPPMAVKGPNGRDPLLEVYDVP-PSVEK 295 L AP P D P PSQ G TPP P L + VP P+ Sbjct: 895 SSRLPAPTPSDFQLQFP-----PSQ-GPHKSPTPP----------PTLHL--VPEPAAPP 936 Query: 296 GLPPSNHHAVYDVPPSVSK---------DVPDGPLLREETYDVPPAFAKAKPFDPARTP- 345 PP V P++ + VP G +L+ + P A + P +P Sbjct: 937 PPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPA 996 Query: 346 ---LVLAAPPPDSPPAEDVYDVPPPAP 369 LV P +P A P PAP Sbjct: 997 ASVLVSGQAPSGTPTAPS--HAPAPAP 1021 Score = 47.0 bits (110), Expect = 8e-05 Identities = 58/218 (26%), Positives = 74/218 (33%), Gaps = 36/218 (16%) Query: 58 NRLKILVGMYDKKPAGPGPGPPATPAQPQPGLHAPAPPASQYTPMLPNTYQPQPDSVYLV 117 N+L + + P PGP P Q QP P PPA P LP P S Sbjct: 839 NQLGVPPPASNPAPTAPGPPQPPLRPQSQPP-EGPLPPA----PHLP------PSSTSSA 887 Query: 118 PTPSKAQQGLYQVPGPSP-QFQSPPAKQTSTFSKQTPH-HPFPSPATDLYQVPPGPGGPA 175 S P PS Q Q PP+ Q PH P P P L P P P Sbjct: 888 VASSSETSSRLPAPTPSDFQLQFPPS--------QGPHKSPTPPPTLHLVPEPAAPPPPP 939 Query: 176 QDIYQ--------VPPSAGMGHDIYQVPPSMDTRSWEGTKPPA----KVVVPTRVGQGYV 223 +Q +P + +QVP + ++ G P A + P V Sbjct: 940 PRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASV 999 Query: 224 YEAAQPEQDEYDIPRHLLAPGPQDIYDVPPVRGLLPSQ 261 + Q P H AP P +PP LLP++ Sbjct: 1000 LVSGQAPSGTPTAPSHAPAPAPMAATGLPP---LLPAE 1034 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 63.2 bits (152), Expect = 1e-09 Identities = 119/452 (26%), Positives = 154/452 (34%), Gaps = 79/452 (17%) Query: 71 PAGPGPGPPATPAQPQPGLHAPAPPASQYTPML---PNTYQPQPDSVYLVPTPSKAQQGL 127 P P P TP P A PP Q P L P P P L P +A L Sbjct: 568 PLQAPPSPLTTPPPETPSSIATPPP--QAPPALASPPLQGLPSPPLSPLATPPPQAPPXL 625 Query: 128 YQVP---GPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVP--PGPGGPAQDIYQVP 182 P PSP SPP +T S Q P+ + A L Q P P P P Q + P Sbjct: 626 ALPPLQAPPSPP-ASPPLSPLATPSPQAPN----ALAVHLLQAPFSPPPSPPVQAPFSPP 680 Query: 183 PSAGMGHDIYQVPPSMDTRSWEGTKPPAKVVVPTRVGQGYVYEAAQPEQDEYDIPRHLLA 242 S PP + + PP+ P +V A P Sbjct: 681 AS----------PPVSPSATPPSQAPPSLAAPPLQVPPS---PPASPPMSPS------AT 721 Query: 243 PGPQDIYDVPPVRGLLPSQYGQEVYDTPPMAVKGPNGRDPLLEVYDVPPSVEKGLPPSNH 302 P PQ PP P Q +PPM+ P+ P VPP + PP Sbjct: 722 PPPQ----APPPLAAPPLQVPPSPPASPPMS---PSATPPPR----VPPLL--AAPP--- 765 Query: 303 HAVYDVPPSVSKDVPDGPLLREETYDVPPAFA----KAKPFDPARTPLVLAAPPPDSPPA 358 VPPS +P PL + PPA A +A P PA P P S P Sbjct: 766 ---LQVPPSPPASLPMSPLAKPPP-QAPPALATPPLQALPSPPASFPGQAPFSPSASLPM 821 Query: 359 EDVYDVPPPAPD-----LYDVPPGLRRPGPGTLYDVPRERVLP-PEVA-DGGVVDSGVYA 411 + PP AP L VPP P PR P P+ + G + + Sbjct: 822 SPLATPPPQAPPVLAAPLLQVPPS---PPASPTLQAPRRPPTPGPDTSVSGPRLTLALAP 878 Query: 412 VPPPAEREAPA---EGKRLSASSTGSTRSSQSA----SSLEVAGPGREPLELEVAVEALA 464 PPP +P+ G L+ S+ +T + + S E P + E+A A Sbjct: 879 GPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPA 938 Query: 465 RLQQGVSATVAHLLDLAGSAGATGSWRSPSEP 496 +G + +A G+ GA W + P Sbjct: 939 AWSRGPAPPLA----FRGAPGAPLPWPPATGP 966 Score = 58.2 bits (139), Expect = 3e-08 Identities = 113/443 (25%), Positives = 150/443 (33%), Gaps = 94/443 (21%) Query: 71 PAGPGPGPPATP-AQPQPGLHAP---APPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQG 126 PA P P ATP +Q P L AP PP+ +P + + P P + P P A Sbjct: 680 PASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQA----PPPLAA--- 732 Query: 127 LYQVPGPSPQFQ---SPPAKQTSTFSKQTPHHPFPSPATDLYQVPPGPGG--PAQDIYQV 181 P Q SPPA + S P P A QVPP P P + + Sbjct: 733 --------PPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKP 784 Query: 182 PPSAGMGHDIYQVPPSMDTRSWEG-TKPPAKVVVPTRVGQGYVYEAAQPEQDEYDIPRHL 240 PP Q PP++ T + PPA + P +P Sbjct: 785 PP---------QAPPALATPPLQALPSPPAS------------FPGQAPFSPSASLPMSP 823 Query: 241 LA-PGPQ-------DIYDVPPVRGLLPSQYGQEVYDT--PPMAVKGPNGRDPLLEVYDVP 290 LA P PQ + VPP P+ T P +V GP + Sbjct: 824 LATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPR----------LT 873 Query: 291 PSVEKGLPPSNHHAVYDVPPSVS-KDVPDGPLLREETYDVPPAFAKAKPFDPARTPLVLA 349 ++ G PP PPS S GP L + + + +D A Sbjct: 874 LALAPGPPP---------PPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAA 924 Query: 350 APPPDSPPAEDVYDVPPPAPDLYDVPPGLRRPGPGTLYDVPRERVLPPEVADGGVVDSGV 409 +PPPD+ ++ P A PP R PG +P P ADG + Sbjct: 925 SPPPDA----ELAACHPAAWSRGPAPPLAFRGAPGA--PLPWPPATGPGSADGLCT---I 975 Query: 410 YAVPPPAEREAPAEGKRLSASSTGSTRSSQSASSLEVAGPGREPLELEVAVEALARLQQG 469 Y P E PA G L + T ++A+ R P + + L LQ Sbjct: 976 YETEGP-ESATPAPG-ALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQAS 1033 Query: 470 VSATVAHLLD----LAGSAGATG 488 V V HLL LA + GA G Sbjct: 1034 V---VQHLLSRTLLLAAAEGAAG 1053 Score = 57.4 bits (137), Expect = 6e-08 Identities = 98/405 (24%), Positives = 136/405 (33%), Gaps = 51/405 (12%) Query: 72 AGPGPGPPATPAQPQPGLHAPAPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQGLYQVP 131 A P P PP A P P P+PP + P+ P + P S+ +P+P Sbjct: 314 ARPVP-PPDNAATPLPATLPPSPPLATPLPLAPPS-PSAPPSLQTLPSPPATPPSQAPPS 371 Query: 132 GPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVPPGPGGPAQDIYQVPPSAGMGHDI 191 +P Q+PP+ QT Q PH S + Q PP P + + + +G Sbjct: 372 MTTPPMQAPPSLQTIP-PIQVPH----SLTSPSLQAPPSP----LALSSLQATTSLGSPT 422 Query: 192 YQVPPSMDTRSWEGTKPPAKVVVPTRVGQGYVYEAAQPEQDEYDIPRHLLAPGPQDIYDV 251 Q S T S T+ A + P+R + P+ P L A P Sbjct: 423 LQATHSFLTMSPRQTQ--ASLTSPSRPA------STPPDSPPLQAPLSLPASPPLQTSLS 474 Query: 252 PPVRGLL------PSQYGQEVYDTPPMAVKGPNGRDPL-LEVYDVPPSVEK-----GLPP 299 P V L P Q + P A PL + PPS++ PP Sbjct: 475 PAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPP 534 Query: 300 SNHHAVYDVPPSVSKDVP-DGPLLREETYDVP-PAFAKAKPF--DPARTPLVLAAPPPDS 355 + PP + P P L P P A P P TP +A PPP + Sbjct: 535 LENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQA 594 Query: 356 PPA--------------EDVYDVPPPAPDLYDVPPGLRRPGPGTLYDVPRERVLPPEVAD 401 PPA + PP AP +PP P P + P+ + Sbjct: 595 PPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPN 654 Query: 402 GGVVD--SGVYAVPPPAEREAPAEGKRLSASSTGSTRSSQSASSL 444 V ++ PP +AP S +T SQ+ SL Sbjct: 655 ALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSL 699 Score = 57.4 bits (137), Expect = 6e-08 Identities = 119/472 (25%), Positives = 161/472 (34%), Gaps = 97/472 (20%) Query: 71 PAGPGPGPPATPAQPQPGLHAPAPPASQYTPMLPN--------------------TYQPQ 110 P+ P PP +P P L PA P Q T + P ++ PQ Sbjct: 444 PSRPASTPPDSPPLQAP-LSLPASPPLQ-TSLSPAVSPLSSPLTIHPLQALSSLASHSPQ 501 Query: 111 PDSVYLVPTPSKAQQGL----YQVPGPS---PQFQS-----PPAKQTSTFSKQTPH-HPF 157 L+ P + Q L Q P S P ++ PP QT++ TPH Sbjct: 502 APLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETP 561 Query: 158 PSPATDLYQVPPGPGGPAQDIYQVPPSAGMGHDIYQVPPSMDTRSWEGTKPPAKVVVPTR 217 P PA Q PP P PP + P S+ T + PPA P Sbjct: 562 PCPAPCPLQAPPSP-------LTTPPP--------ETPSSIATPPPQA--PPALASPPL- 603 Query: 218 VGQGYVYEAAQPEQDEYDIPRHLLAPGPQDIYDVPPVRGLLPSQYGQEVYDTPPMA-VKG 276 QG P L P PQ PP L P Q +PP++ + Sbjct: 604 --QGLPSPPLSP----------LATPPPQ----APPXLALPPLQAPPSPPASPPLSPLAT 647 Query: 277 PNGRDP------LLEVYDVPPSVEKGLPPSNHHAVYDVPPSVSKDVPDGPLLREETYDVP 330 P+ + P LL+ PP P + A V PS + P L VP Sbjct: 648 PSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVP 707 Query: 331 PAFAKAKPFDPARTPLVLAAPPPDSPPAEDVYDVPPPAPDLYDVPPGLRRPGPGTLYDVP 390 P+ + P P+ TP A PP +PP + V PP +P + P P L P Sbjct: 708 PSPPASPPMSPSATPPPQAPPPLAAPPLQ-VPPSPPASPPM--SPSATPPPRVPPLLAAP 764 Query: 391 RERVLPPEVADGGVVDSGVYAVPPPAEREAPAEGKRLSASSTGSTRSSQSASSLEVAGPG 450 +V P A + A PPP A A T Q+ S + PG Sbjct: 765 PLQVPPSPPAS---LPMSPLAKPPPQAPPALA------------TPPLQALPSPPASFPG 809 Query: 451 REPL--ELEVAVEALAR-LQQGVSATVAHLLDLAGSAGATGSWRSPSEPQEP 499 + P + + LA Q A LL + S A+ + ++P P P Sbjct: 810 QAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTP 861 Score = 45.4 bits (106), Expect = 2e-04 Identities = 78/361 (21%), Positives = 119/361 (32%), Gaps = 61/361 (16%) Query: 132 GPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVPPGPGGPAQDIYQVPPSAGMGHDI 191 GP+P SP + S + P P+P+ + P GP + + S+ H Sbjct: 166 GPTPGTPSPAMARRSRAAGTEVGLPRPAPSA---RPRPPTEGPRKSV-----SSASEHST 217 Query: 192 YQVPPSMDTRSWEG---TKPPAKVVVPTRVGQGYVYEAAQPEQDEYDIPRHLLAPGPQDI 248 + P+ R G +P ++ + + + + P H P P+ + Sbjct: 218 TEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGL 277 Query: 249 YDVPPVRGLLPSQYGQEVYDTPPMAVKGPNGRDPLLEVYDVPPSVEKGLPPSNHHAVYDV 308 + L P Q D P GP PL PS K P V Sbjct: 278 ------QALRPPQVTPPRKDAAPAL--GPLSSSPLATP---SPSGTKARP---------V 317 Query: 309 PPSVSKDVPDGPLLREETYDVPPAFAKAKPFDPARTPLVLAAPPPDSPPAEDVYDVPPPA 368 PP PD P A P P TPL LA P P +PP+ PP Sbjct: 318 PP------PDNA--------ATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPAT 363 Query: 369 PDLYDVPPGLRRPGPGTLYDVPRERVLPPEVADGGVVDSGVYAVPPPAEREAPAEGKRLS 428 P PP + P + P + +PP + + A P P + L Sbjct: 364 PP-SQAPPSMTTP---PMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLG 419 Query: 429 ASSTGSTRSSQSASSLEVAG------------PGREPLELEVAVEALARLQQGVSATVAH 476 + + +T S + S + P PL+ +++ A LQ +S V+ Sbjct: 420 SPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSP 479 Query: 477 L 477 L Sbjct: 480 L 480 Score = 44.3 bits (103), Expect = 5e-04 Identities = 93/407 (22%), Positives = 131/407 (32%), Gaps = 66/407 (16%) Query: 56 PGNRLKILVGMYDKKPAGPGPGPPATPAQPQPGLHAPAPPASQYTPMLP-NTYQPQPDSV 114 P R + G ++PA ATP A + P+++ TP P + QP+P + Sbjct: 222 PAARRRPSAGGGLQRPASRSLSSSATPLSSP----ARSGPSARGTPRAPAHPSQPKPKGL 277 Query: 115 YLVPTPSKAQQGLYQVPGPSPQFQSPPAKQTSTFSKQTPHHP------------FPSP-- 160 + P P P SP A + + +K P P PSP Sbjct: 278 QALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPL 337 Query: 161 ATDLYQVPPGPGG----------PAQDIYQVPPSAGMGHDIYQVPPSMDT----RSWEGT 206 AT L PP P PA Q PPS M Q PPS+ T + Sbjct: 338 ATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPS--MTTPPMQAPPSLQTIPPIQVPHSL 395 Query: 207 KPPAKVVVPTRVGQGYVYEAAQPEQDEYDIPRHLLAPGPQDIYDVPPVRGLLPSQYGQEV 266 P+ P+ + + L P+ PS+ Sbjct: 396 TSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQ----TQASLTSPSRPASTP 451 Query: 267 YDTPPMAVKGPNGRDPLLEVYDVPPSVEKGLPPSNHHAVYDVPPSVSKDVPDGPL----- 321 D+PP+ P L+ + P+V P H + + S++ P PL Sbjct: 452 PDSPPLQAPLSLPASPPLQT-SLSPAVSPLSSPLTIHPLQAL-SSLASHSPQAPLSSLIM 509 Query: 322 --------LREETYDVPPAFAKAKPFDP----ARTPLVLAAPPPDSPPAEDVYDVPPPAP 369 L + PPA P + A PL A+ P +P E P PAP Sbjct: 510 PPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLE---TPPCPAP 566 Query: 370 DLYDVPPG-LRRPGPGTLYDVPRERVLPPEVADGGVVDSGVYAVPPP 415 PP L P P T P PP A + + +P P Sbjct: 567 CPLQAPPSPLTTPPPET----PSSIATPPPQAPPALASPPLQGLPSP 609 Score = 31.2 bits (69), Expect = 4.4 Identities = 39/143 (27%), Positives = 54/143 (37%), Gaps = 17/143 (11%) Query: 368 APDLYDVPPGLRRPGPGTLYDVPRERVLPPEVADGGVVDSGVYAVPPPAEREAPAEGKRL 427 AP + G RR G P + A G V G+ P A P EG R Sbjct: 150 APKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEV--GLPRPAPSARPRPPTEGPRK 207 Query: 428 SASSTG---STRSSQSASSLEVAGPGREPLELEVAVEALARLQQGVSATVAHLLDLAGSA 484 S SS +T S +A AG G + + +S++ L A S Sbjct: 208 SVSSASEHSTTEPSPAARRRPSAGGGLQ-----------RPASRSLSSSATPLSSPARSG 256 Query: 485 -GATGSWRSPSEPQEPLVQDLQA 506 A G+ R+P+ P +P + LQA Sbjct: 257 PSARGTPRAPAHPSQPKPKGLQA 279 >gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo sapiens] Length = 1188 Score = 62.4 bits (150), Expect = 2e-09 Identities = 82/316 (25%), Positives = 115/316 (36%), Gaps = 49/316 (15%) Query: 71 PAGPGPGPPATPAQPQPGLHAPAPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQ-----Q 125 P GP PGPP ++P G P+PP S P P +P P P P + Sbjct: 143 PPGPAPGPPQDISEPPGGSPLPSPP-STAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPH 201 Query: 126 GLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVPPGPGGPAQDIYQVPPSA 185 L P+P PPA + + P P P+PA PP P P ++ P Sbjct: 202 TLSSPSIPTPPDFIPPAPPLAFLAPPPP--PVPAPA------PPAPASPHTVGTRLFPPG 253 Query: 186 GMGHDIYQVPPSMDTRSWEGTK--PPAKVVVPTRVGQGYVYEAAQPEQDEYDIPRHLLAP 243 G+ ++ +++ R E T+ PP P G PE PR P Sbjct: 254 GVTK--WKSDVALNGRQAEATRASPPRSPAEPKGSALG-----PNPE-PHLTFPRSFKVP 305 Query: 244 GPQDIYDVPPVR-GLLPSQYGQEVYDTPPMAVKGPNGRDPLLEVYDVPPSVEKGLPPSNH 302 P PVR +P Q QE A K R PL + + P+ + + Sbjct: 306 PP------TPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQ---VYPDR 356 Query: 303 HAVYDVPPSVSKDVPDGPLLREETYDVPPAFAKAKPFDPARTPLVLAAPPPDSPPAEDVY 362 D P + P P L + ++++ + A TP PP +PP Sbjct: 357 APEPDCPGELKATAPASPRLGQ---------SQSQADERAGTPPPAPPLPPPAPP----- 402 Query: 363 DVPPPAPDLYDVPPGL 378 +PPPAP L P L Sbjct: 403 -LPPPAPPLPPAAPPL 417 Score = 47.8 bits (112), Expect = 5e-05 Identities = 87/322 (27%), Positives = 110/322 (34%), Gaps = 76/322 (23%) Query: 143 KQT--STFSKQTPHHPFPSPATDLYQVPPGPGGPAQDIYQVPPSAGMGHD-IYQVPPSMD 199 KQT TFSK +P+T LY P P + P G D IY + Sbjct: 4 KQTVQGTFSKLFGKKHTTTPSTSLYATNP----PWIFTQEAPEEGTGGFDGIYYGDNRFN 59 Query: 200 TRSWEGTKP--------PAKVVVPTRVGQGYVYEAAQPEQDEYDIPRHL-----LAPGPQ 246 T S GT P +P + + P + + + L G Sbjct: 60 TVSESGTATLKARPRVRPLLTFLPLNAQENHGLAVPTPSVPDDFADKEVTGTSSLVNGNL 119 Query: 247 DIYDVPPVRGLLPSQYGQEVY---------DTPPMAVKGPNGRDPLLEVYDVPPSVEKGL 297 +Y V L P QYGQ++ PP + P G PL PPS Sbjct: 120 RLYS--SVGDLRPGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPL----PSPPSTAPPP 173 Query: 298 PPSNHHAVYDVPPSVSKDVPDGPLLREETYDVP-----PAFAKAKPFDPARTPLVLAAPP 352 PP + + PP S P P+L E P P+ F P PL APP Sbjct: 174 PP----LLLEPPPPPSMAPPPPPVL--EALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPP 227 Query: 353 PDSPPAEDVYDVPPPAPDLYDVPPGLRRPGPGTLYDVPRERVLPP--------EVADGGV 404 P PP VP PAP P P + + V R+ PP +VA G Sbjct: 228 P--PP------VPAPAP-----------PAPASPHTV-GTRLFPPGGVTKWKSDVALNGR 267 Query: 405 VDSGVYAVPP--PAEREAPAEG 424 A PP PAE + A G Sbjct: 268 QAEATRASPPRSPAEPKGSALG 289 Score = 37.7 bits (86), Expect = 0.047 Identities = 103/467 (22%), Positives = 148/467 (31%), Gaps = 74/467 (15%) Query: 71 PAGPGPGPPATPAQPQPGLHAPAPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQGLYQV 130 PA P G + A + G PAPP P LP P P + +P KA Sbjct: 371 PASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAH----- 425 Query: 131 PGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVPPGPGGPAQ--------DIYQVP 182 P F P K +S K P+ PSP P P+Q Y Sbjct: 426 --PPAGFTKTP-KSSSPALKPKPNP--PSPENTASSAPVDWRDPSQMEKLRNELAAYLCG 480 Query: 183 PSAGMGHDIYQVPPSMDTRSWEGTKPPAKVVVPTRVGQGYVYEAAQPEQDEYDIPRHLLA 242 ++ P++ +S EG K P R+ + + + +P L Sbjct: 481 SRREDRFLSHRPGPTVAPQSKEGKKGP-------RLPEKETLLSLPAKDTPPGVPEKSLG 533 Query: 243 PGPQDIYDVPPVRGLLPSQYGQEVYDTPPMAVKGPNGRDPLLEVYDVPPSVEKGLPPSNH 302 + P L Y + D+P +V+ LE + + EK PS Sbjct: 534 GSSLTETEAAPSLTLPSVDYIPQ--DSPTPSVRQIRNE---LEA-RLSSAAEKEAKPS-- 585 Query: 303 HAVYDVPPS--------VSKDVPDGPLLREETYDVPPAFAKAKPFDPARTPLVL------ 348 + +PP D L + ++PP P + +L Sbjct: 586 --IGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPP 643 Query: 349 -AAPPPDSPPAEDVYDVPPPAPDLYDVPPGLRRPGPGTLYDVPRERVLPPEVADGGVV-- 405 A P P PP ++ PP L P GP T P + P +A Sbjct: 644 KATPEPAIPPKATLWPATPPKATLGPATPLKATSGPTT----PLKATSGPAIASTATTLP 699 Query: 406 ----------DSGVYAVP-PPAERE--APAEGKRLSASSTGSTRSSQSASSLEVAGPGRE 452 DSG P PA +E P++ + + S + +Q A S P Sbjct: 700 TTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTS 759 Query: 453 PLELEVAVEALARL-QQGVSATVAHLLDLAGSAGATGSWRSPSEPQE 498 P EV Q +S VA ++ GA G P EP E Sbjct: 760 PGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAG----PGEPVE 802 >gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo sapiens] Length = 1188 Score = 62.4 bits (150), Expect = 2e-09 Identities = 82/316 (25%), Positives = 115/316 (36%), Gaps = 49/316 (15%) Query: 71 PAGPGPGPPATPAQPQPGLHAPAPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQ-----Q 125 P GP PGPP ++P G P+PP S P P +P P P P + Sbjct: 143 PPGPAPGPPQDISEPPGGSPLPSPP-STAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPH 201 Query: 126 GLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVPPGPGGPAQDIYQVPPSA 185 L P+P PPA + + P P P+PA PP P P ++ P Sbjct: 202 TLSSPSIPTPPDFIPPAPPLAFLAPPPP--PVPAPA------PPAPASPHTVGTRLFPPG 253 Query: 186 GMGHDIYQVPPSMDTRSWEGTK--PPAKVVVPTRVGQGYVYEAAQPEQDEYDIPRHLLAP 243 G+ ++ +++ R E T+ PP P G PE PR P Sbjct: 254 GVTK--WKSDVALNGRQAEATRASPPRSPAEPKGSALG-----PNPE-PHLTFPRSFKVP 305 Query: 244 GPQDIYDVPPVR-GLLPSQYGQEVYDTPPMAVKGPNGRDPLLEVYDVPPSVEKGLPPSNH 302 P PVR +P Q QE A K R PL + + P+ + + Sbjct: 306 PP------TPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQ---VYPDR 356 Query: 303 HAVYDVPPSVSKDVPDGPLLREETYDVPPAFAKAKPFDPARTPLVLAAPPPDSPPAEDVY 362 D P + P P L + ++++ + A TP PP +PP Sbjct: 357 APEPDCPGELKATAPASPRLGQ---------SQSQADERAGTPPPAPPLPPPAPP----- 402 Query: 363 DVPPPAPDLYDVPPGL 378 +PPPAP L P L Sbjct: 403 -LPPPAPPLPPAAPPL 417 Score = 47.8 bits (112), Expect = 5e-05 Identities = 87/322 (27%), Positives = 110/322 (34%), Gaps = 76/322 (23%) Query: 143 KQT--STFSKQTPHHPFPSPATDLYQVPPGPGGPAQDIYQVPPSAGMGHD-IYQVPPSMD 199 KQT TFSK +P+T LY P P + P G D IY + Sbjct: 4 KQTVQGTFSKLFGKKHTTTPSTSLYATNP----PWIFTQEAPEEGTGGFDGIYYGDNRFN 59 Query: 200 TRSWEGTKP--------PAKVVVPTRVGQGYVYEAAQPEQDEYDIPRHL-----LAPGPQ 246 T S GT P +P + + P + + + L G Sbjct: 60 TVSESGTATLKARPRVRPLLTFLPLNAQENHGLAVPTPSVPDDFADKEVTGTSSLVNGNL 119 Query: 247 DIYDVPPVRGLLPSQYGQEVY---------DTPPMAVKGPNGRDPLLEVYDVPPSVEKGL 297 +Y V L P QYGQ++ PP + P G PL PPS Sbjct: 120 RLYS--SVGDLRPGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPL----PSPPSTAPPP 173 Query: 298 PPSNHHAVYDVPPSVSKDVPDGPLLREETYDVP-----PAFAKAKPFDPARTPLVLAAPP 352 PP + + PP S P P+L E P P+ F P PL APP Sbjct: 174 PP----LLLEPPPPPSMAPPPPPVL--EALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPP 227 Query: 353 PDSPPAEDVYDVPPPAPDLYDVPPGLRRPGPGTLYDVPRERVLPP--------EVADGGV 404 P PP VP PAP P P + + V R+ PP +VA G Sbjct: 228 P--PP------VPAPAP-----------PAPASPHTV-GTRLFPPGGVTKWKSDVALNGR 267 Query: 405 VDSGVYAVPP--PAEREAPAEG 424 A PP PAE + A G Sbjct: 268 QAEATRASPPRSPAEPKGSALG 289 Score = 37.7 bits (86), Expect = 0.047 Identities = 103/467 (22%), Positives = 148/467 (31%), Gaps = 74/467 (15%) Query: 71 PAGPGPGPPATPAQPQPGLHAPAPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQGLYQV 130 PA P G + A + G PAPP P LP P P + +P KA Sbjct: 371 PASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAH----- 425 Query: 131 PGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVPPGPGGPAQ--------DIYQVP 182 P F P K +S K P+ PSP P P+Q Y Sbjct: 426 --PPAGFTKTP-KSSSPALKPKPNP--PSPENTASSAPVDWRDPSQMEKLRNELAAYLCG 480 Query: 183 PSAGMGHDIYQVPPSMDTRSWEGTKPPAKVVVPTRVGQGYVYEAAQPEQDEYDIPRHLLA 242 ++ P++ +S EG K P R+ + + + +P L Sbjct: 481 SRREDRFLSHRPGPTVAPQSKEGKKGP-------RLPEKETLLSLPAKDTPPGVPEKSLG 533 Query: 243 PGPQDIYDVPPVRGLLPSQYGQEVYDTPPMAVKGPNGRDPLLEVYDVPPSVEKGLPPSNH 302 + P L Y + D+P +V+ LE + + EK PS Sbjct: 534 GSSLTETEAAPSLTLPSVDYIPQ--DSPTPSVRQIRNE---LEA-RLSSAAEKEAKPS-- 585 Query: 303 HAVYDVPPS--------VSKDVPDGPLLREETYDVPPAFAKAKPFDPARTPLVL------ 348 + +PP D L + ++PP P + +L Sbjct: 586 --IGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPP 643 Query: 349 -AAPPPDSPPAEDVYDVPPPAPDLYDVPPGLRRPGPGTLYDVPRERVLPPEVADGGVV-- 405 A P P PP ++ PP L P GP T P + P +A Sbjct: 644 KATPEPAIPPKATLWPATPPKATLGPATPLKATSGPTT----PLKATSGPAIASTATTLP 699 Query: 406 ----------DSGVYAVP-PPAERE--APAEGKRLSASSTGSTRSSQSASSLEVAGPGRE 452 DSG P PA +E P++ + + S + +Q A S P Sbjct: 700 TTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTS 759 Query: 453 PLELEVAVEALARL-QQGVSATVAHLLDLAGSAGATGSWRSPSEPQE 498 P EV Q +S VA ++ GA G P EP E Sbjct: 760 PGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAG----PGEPVE 802 >gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sapiens] Length = 1188 Score = 62.4 bits (150), Expect = 2e-09 Identities = 82/316 (25%), Positives = 115/316 (36%), Gaps = 49/316 (15%) Query: 71 PAGPGPGPPATPAQPQPGLHAPAPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQ-----Q 125 P GP PGPP ++P G P+PP S P P +P P P P + Sbjct: 143 PPGPAPGPPQDISEPPGGSPLPSPP-STAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPH 201 Query: 126 GLYQVPGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVPPGPGGPAQDIYQVPPSA 185 L P+P PPA + + P P P+PA PP P P ++ P Sbjct: 202 TLSSPSIPTPPDFIPPAPPLAFLAPPPP--PVPAPA------PPAPASPHTVGTRLFPPG 253 Query: 186 GMGHDIYQVPPSMDTRSWEGTK--PPAKVVVPTRVGQGYVYEAAQPEQDEYDIPRHLLAP 243 G+ ++ +++ R E T+ PP P G PE PR P Sbjct: 254 GVTK--WKSDVALNGRQAEATRASPPRSPAEPKGSALG-----PNPE-PHLTFPRSFKVP 305 Query: 244 GPQDIYDVPPVR-GLLPSQYGQEVYDTPPMAVKGPNGRDPLLEVYDVPPSVEKGLPPSNH 302 P PVR +P Q QE A K R PL + + P+ + + Sbjct: 306 PP------TPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQ---VYPDR 356 Query: 303 HAVYDVPPSVSKDVPDGPLLREETYDVPPAFAKAKPFDPARTPLVLAAPPPDSPPAEDVY 362 D P + P P L + ++++ + A TP PP +PP Sbjct: 357 APEPDCPGELKATAPASPRLGQ---------SQSQADERAGTPPPAPPLPPPAPP----- 402 Query: 363 DVPPPAPDLYDVPPGL 378 +PPPAP L P L Sbjct: 403 -LPPPAPPLPPAAPPL 417 Score = 47.8 bits (112), Expect = 5e-05 Identities = 87/322 (27%), Positives = 110/322 (34%), Gaps = 76/322 (23%) Query: 143 KQT--STFSKQTPHHPFPSPATDLYQVPPGPGGPAQDIYQVPPSAGMGHD-IYQVPPSMD 199 KQT TFSK +P+T LY P P + P G D IY + Sbjct: 4 KQTVQGTFSKLFGKKHTTTPSTSLYATNP----PWIFTQEAPEEGTGGFDGIYYGDNRFN 59 Query: 200 TRSWEGTKP--------PAKVVVPTRVGQGYVYEAAQPEQDEYDIPRHL-----LAPGPQ 246 T S GT P +P + + P + + + L G Sbjct: 60 TVSESGTATLKARPRVRPLLTFLPLNAQENHGLAVPTPSVPDDFADKEVTGTSSLVNGNL 119 Query: 247 DIYDVPPVRGLLPSQYGQEVY---------DTPPMAVKGPNGRDPLLEVYDVPPSVEKGL 297 +Y V L P QYGQ++ PP + P G PL PPS Sbjct: 120 RLYS--SVGDLRPGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPL----PSPPSTAPPP 173 Query: 298 PPSNHHAVYDVPPSVSKDVPDGPLLREETYDVP-----PAFAKAKPFDPARTPLVLAAPP 352 PP + + PP S P P+L E P P+ F P PL APP Sbjct: 174 PP----LLLEPPPPPSMAPPPPPVL--EALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPP 227 Query: 353 PDSPPAEDVYDVPPPAPDLYDVPPGLRRPGPGTLYDVPRERVLPP--------EVADGGV 404 P PP VP PAP P P + + V R+ PP +VA G Sbjct: 228 P--PP------VPAPAP-----------PAPASPHTV-GTRLFPPGGVTKWKSDVALNGR 267 Query: 405 VDSGVYAVPP--PAEREAPAEG 424 A PP PAE + A G Sbjct: 268 QAEATRASPPRSPAEPKGSALG 289 Score = 37.7 bits (86), Expect = 0.047 Identities = 103/467 (22%), Positives = 148/467 (31%), Gaps = 74/467 (15%) Query: 71 PAGPGPGPPATPAQPQPGLHAPAPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQGLYQV 130 PA P G + A + G PAPP P LP P P + +P KA Sbjct: 371 PASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAH----- 425 Query: 131 PGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVPPGPGGPAQ--------DIYQVP 182 P F P K +S K P+ PSP P P+Q Y Sbjct: 426 --PPAGFTKTP-KSSSPALKPKPNP--PSPENTASSAPVDWRDPSQMEKLRNELAAYLCG 480 Query: 183 PSAGMGHDIYQVPPSMDTRSWEGTKPPAKVVVPTRVGQGYVYEAAQPEQDEYDIPRHLLA 242 ++ P++ +S EG K P R+ + + + +P L Sbjct: 481 SRREDRFLSHRPGPTVAPQSKEGKKGP-------RLPEKETLLSLPAKDTPPGVPEKSLG 533 Query: 243 PGPQDIYDVPPVRGLLPSQYGQEVYDTPPMAVKGPNGRDPLLEVYDVPPSVEKGLPPSNH 302 + P L Y + D+P +V+ LE + + EK PS Sbjct: 534 GSSLTETEAAPSLTLPSVDYIPQ--DSPTPSVRQIRNE---LEA-RLSSAAEKEAKPS-- 585 Query: 303 HAVYDVPPS--------VSKDVPDGPLLREETYDVPPAFAKAKPFDPARTPLVL------ 348 + +PP D L + ++PP P + +L Sbjct: 586 --IGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPP 643 Query: 349 -AAPPPDSPPAEDVYDVPPPAPDLYDVPPGLRRPGPGTLYDVPRERVLPPEVADGGVV-- 405 A P P PP ++ PP L P GP T P + P +A Sbjct: 644 KATPEPAIPPKATLWPATPPKATLGPATPLKATSGPTT----PLKATSGPAIASTATTLP 699 Query: 406 ----------DSGVYAVP-PPAERE--APAEGKRLSASSTGSTRSSQSASSLEVAGPGRE 452 DSG P PA +E P++ + + S + +Q A S P Sbjct: 700 TTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTS 759 Query: 453 PLELEVAVEALARL-QQGVSATVAHLLDLAGSAGATGSWRSPSEPQE 498 P EV Q +S VA ++ GA G P EP E Sbjct: 760 PGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAG----PGEPVE 802 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.313 0.132 0.396 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 44,280,855 Number of Sequences: 37866 Number of extensions: 2922303 Number of successful extensions: 21900 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 254 Number of HSP's successfully gapped in prelim test: 1089 Number of HSP's that attempted gapping in prelim test: 12700 Number of HSP's gapped (non-prelim): 6739 length of query: 870 length of database: 18,247,518 effective HSP length: 111 effective length of query: 759 effective length of database: 14,044,392 effective search space: 10659693528 effective search space used: 10659693528 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.