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Search of human proteins with 42740907
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|42740907 clusterin isoform 2 [Homo sapiens]
(449 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|42740907 clusterin isoform 2 [Homo sapiens] 914 0.0
gi|42716297 clusterin isoform 1 [Homo sapiens] 914 0.0
gi|40316926 clusterin-like 1 (retinal) [Homo sapiens] 156 3e-38
gi|7657490 clusterin-like 1 (retinal) [Homo sapiens] 156 3e-38
gi|118498356 kinectin 1 isoform a [Homo sapiens] 37 0.036
gi|33620775 kinectin 1 isoform a [Homo sapiens] 37 0.036
gi|7705682 geminin [Homo sapiens] 36 0.062
gi|111955162 5-azacytidine induced 1 isoform b [Homo sapiens] 36 0.062
gi|111955084 5-azacytidine induced 1 isoform a [Homo sapiens] 36 0.062
gi|118498362 kinectin 1 isoform b [Homo sapiens] 36 0.081
gi|118498368 kinectin 1 isoform c [Homo sapiens] 36 0.081
gi|9910266 kinesin family member 15 [Homo sapiens] 35 0.11
gi|47174859 tripartite motif-containing 46 [Homo sapiens] 35 0.11
gi|31982906 cingulin-like 1 [Homo sapiens] 35 0.14
gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo... 35 0.18
gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo... 35 0.18
gi|239745140 PREDICTED: similar to hect domain and RLD 2 [Homo s... 35 0.18
gi|51479166 bicaudal D homolog 2 isoform 1 [Homo sapiens] 35 0.18
gi|38683807 ankyrin repeat domain protein 17 isoform a [Homo sap... 35 0.18
gi|21735417 bicaudal D homolog 2 isoform 2 [Homo sapiens] 35 0.18
gi|38570058 hypothetical protein LOC80129 [Homo sapiens] 34 0.24
gi|19924131 RAD50 homolog isoform 2 [Homo sapiens] 34 0.24
gi|19924129 RAD50 homolog isoform 1 [Homo sapiens] 34 0.24
gi|154689866 hypothetical protein LOC9778 [Homo sapiens] 34 0.24
gi|154689751 hypothetical protein LOC9778 [Homo sapiens] 34 0.24
gi|93102364 SWAP-70 protein [Homo sapiens] 34 0.31
gi|22027627 TNF receptor-associated factor 5 [Homo sapiens] 34 0.31
gi|77404348 TNF receptor-associated factor 5 [Homo sapiens] 34 0.31
gi|11321603 TNF receptor-associated factor 5 [Homo sapiens] 34 0.31
gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens] 34 0.31
>gi|42740907 clusterin isoform 2 [Homo sapiens]
Length = 449
Score = 914 bits (2363), Expect = 0.0
Identities = 449/449 (100%), Positives = 449/449 (100%)
Query: 1 MMKTLLLFVGLLLTWESGQVLGDQTVSDNELQEMSNQGSKYVNKEIQNAVNGVKQIKTLI 60
MMKTLLLFVGLLLTWESGQVLGDQTVSDNELQEMSNQGSKYVNKEIQNAVNGVKQIKTLI
Sbjct: 1 MMKTLLLFVGLLLTWESGQVLGDQTVSDNELQEMSNQGSKYVNKEIQNAVNGVKQIKTLI 60
Query: 61 EKTNEERKTLLSNLEEAKKKKEDALNETRESETKLKELPGVCNETMMALWEECKPCLKQT 120
EKTNEERKTLLSNLEEAKKKKEDALNETRESETKLKELPGVCNETMMALWEECKPCLKQT
Sbjct: 61 EKTNEERKTLLSNLEEAKKKKEDALNETRESETKLKELPGVCNETMMALWEECKPCLKQT 120
Query: 121 CMKFYARVCRSGSGLVGRQLEEFLNQSSPFYFWMNGDRIDSLLENDRQQTHMLDVMQDHF 180
CMKFYARVCRSGSGLVGRQLEEFLNQSSPFYFWMNGDRIDSLLENDRQQTHMLDVMQDHF
Sbjct: 121 CMKFYARVCRSGSGLVGRQLEEFLNQSSPFYFWMNGDRIDSLLENDRQQTHMLDVMQDHF 180
Query: 181 SRASSIIDELFQDRFFTREPQDTYHYLPFSLPHRRPHFFFPKSRIVRSLMPFSPYEPLNF 240
SRASSIIDELFQDRFFTREPQDTYHYLPFSLPHRRPHFFFPKSRIVRSLMPFSPYEPLNF
Sbjct: 181 SRASSIIDELFQDRFFTREPQDTYHYLPFSLPHRRPHFFFPKSRIVRSLMPFSPYEPLNF 240
Query: 241 HAMFQPFLEMIHEAQQAMDIHFHSPAFQHPPTEFIREGDDDRTVCREIRHNSTGCLRMKD 300
HAMFQPFLEMIHEAQQAMDIHFHSPAFQHPPTEFIREGDDDRTVCREIRHNSTGCLRMKD
Sbjct: 241 HAMFQPFLEMIHEAQQAMDIHFHSPAFQHPPTEFIREGDDDRTVCREIRHNSTGCLRMKD 300
Query: 301 QCDKCREILSVDCSTNNPSQAKLRRELDESLQVAERLTRKYNELLKSYQWKMLNTSSLLE 360
QCDKCREILSVDCSTNNPSQAKLRRELDESLQVAERLTRKYNELLKSYQWKMLNTSSLLE
Sbjct: 301 QCDKCREILSVDCSTNNPSQAKLRRELDESLQVAERLTRKYNELLKSYQWKMLNTSSLLE 360
Query: 361 QLNEQFNWVSRLANLTQGEDQYYLRVTTVASHTSDSDVPSGVTEVVVKLFDSDPITVTVP 420
QLNEQFNWVSRLANLTQGEDQYYLRVTTVASHTSDSDVPSGVTEVVVKLFDSDPITVTVP
Sbjct: 361 QLNEQFNWVSRLANLTQGEDQYYLRVTTVASHTSDSDVPSGVTEVVVKLFDSDPITVTVP 420
Query: 421 VEVSRKNPKFMETVAEKALQEYRKKHREE 449
VEVSRKNPKFMETVAEKALQEYRKKHREE
Sbjct: 421 VEVSRKNPKFMETVAEKALQEYRKKHREE 449
>gi|42716297 clusterin isoform 1 [Homo sapiens]
Length = 501
Score = 914 bits (2363), Expect = 0.0
Identities = 449/449 (100%), Positives = 449/449 (100%)
Query: 1 MMKTLLLFVGLLLTWESGQVLGDQTVSDNELQEMSNQGSKYVNKEIQNAVNGVKQIKTLI 60
MMKTLLLFVGLLLTWESGQVLGDQTVSDNELQEMSNQGSKYVNKEIQNAVNGVKQIKTLI
Sbjct: 53 MMKTLLLFVGLLLTWESGQVLGDQTVSDNELQEMSNQGSKYVNKEIQNAVNGVKQIKTLI 112
Query: 61 EKTNEERKTLLSNLEEAKKKKEDALNETRESETKLKELPGVCNETMMALWEECKPCLKQT 120
EKTNEERKTLLSNLEEAKKKKEDALNETRESETKLKELPGVCNETMMALWEECKPCLKQT
Sbjct: 113 EKTNEERKTLLSNLEEAKKKKEDALNETRESETKLKELPGVCNETMMALWEECKPCLKQT 172
Query: 121 CMKFYARVCRSGSGLVGRQLEEFLNQSSPFYFWMNGDRIDSLLENDRQQTHMLDVMQDHF 180
CMKFYARVCRSGSGLVGRQLEEFLNQSSPFYFWMNGDRIDSLLENDRQQTHMLDVMQDHF
Sbjct: 173 CMKFYARVCRSGSGLVGRQLEEFLNQSSPFYFWMNGDRIDSLLENDRQQTHMLDVMQDHF 232
Query: 181 SRASSIIDELFQDRFFTREPQDTYHYLPFSLPHRRPHFFFPKSRIVRSLMPFSPYEPLNF 240
SRASSIIDELFQDRFFTREPQDTYHYLPFSLPHRRPHFFFPKSRIVRSLMPFSPYEPLNF
Sbjct: 233 SRASSIIDELFQDRFFTREPQDTYHYLPFSLPHRRPHFFFPKSRIVRSLMPFSPYEPLNF 292
Query: 241 HAMFQPFLEMIHEAQQAMDIHFHSPAFQHPPTEFIREGDDDRTVCREIRHNSTGCLRMKD 300
HAMFQPFLEMIHEAQQAMDIHFHSPAFQHPPTEFIREGDDDRTVCREIRHNSTGCLRMKD
Sbjct: 293 HAMFQPFLEMIHEAQQAMDIHFHSPAFQHPPTEFIREGDDDRTVCREIRHNSTGCLRMKD 352
Query: 301 QCDKCREILSVDCSTNNPSQAKLRRELDESLQVAERLTRKYNELLKSYQWKMLNTSSLLE 360
QCDKCREILSVDCSTNNPSQAKLRRELDESLQVAERLTRKYNELLKSYQWKMLNTSSLLE
Sbjct: 353 QCDKCREILSVDCSTNNPSQAKLRRELDESLQVAERLTRKYNELLKSYQWKMLNTSSLLE 412
Query: 361 QLNEQFNWVSRLANLTQGEDQYYLRVTTVASHTSDSDVPSGVTEVVVKLFDSDPITVTVP 420
QLNEQFNWVSRLANLTQGEDQYYLRVTTVASHTSDSDVPSGVTEVVVKLFDSDPITVTVP
Sbjct: 413 QLNEQFNWVSRLANLTQGEDQYYLRVTTVASHTSDSDVPSGVTEVVVKLFDSDPITVTVP 472
Query: 421 VEVSRKNPKFMETVAEKALQEYRKKHREE 449
VEVSRKNPKFMETVAEKALQEYRKKHREE
Sbjct: 473 VEVSRKNPKFMETVAEKALQEYRKKHREE 501
>gi|40316926 clusterin-like 1 (retinal) [Homo sapiens]
Length = 466
Score = 156 bits (395), Expect = 3e-38
Identities = 122/478 (25%), Positives = 219/478 (45%), Gaps = 51/478 (10%)
Query: 1 MMKTLLLFVGLLL---------TWESGQVLGDQTVSDNELQEMSNQGSKYVNKEIQNAVN 51
M LL+F+ LL TW+ D+T L+ S G ++E++ A+
Sbjct: 1 MKPPLLVFIVCLLWLKDSHCAPTWK------DKTAISENLKSFSEVGEIDADEEVKKALT 54
Query: 52 GVKQIKTLIEKTNEERKTLLSNLEEAKKKKEDALNETRESETKLKELPGVCNETMMALWE 111
G+KQ+K ++E+ +E L+S L++ +++K++AL E + L+E +C E++ W
Sbjct: 55 GIKQMKIMMERKEKEHTNLMSTLKKCREEKQEALKLLNEVQEHLEEEERLCRESLADSWG 114
Query: 112 ECKPCLKQTCMKFYARVCRSGSGLVGRQLEEFLNQSSPFYFWMNGDR------IDSLLEN 165
EC+ CL+ CM+ Y C+ V ++E F + F F + D + L+E
Sbjct: 115 ECRSCLENNCMRIYT-TCQPSWSSVKNKIERFFRKIYQFLFPFHEDNEKDLPISEKLIEE 173
Query: 166 DRQQTHMLDVMQDHFSRASSIIDELFQDRF-FTREPQDTY------HYLPFSLPHRRPHF 218
D Q T M DV FS+ + ++ LF F R+ Q + H++ P+F
Sbjct: 174 DAQLTQMEDV----FSQLTVDVNSLFNRSFNVFRQMQQEFDQTFQSHFIS-DTDLTEPYF 228
Query: 219 F--FPKSRIVRSLMPFSPYEPLNFHAMFQPFLEMIHEA---------QQAMDIHFHSPAF 267
F F K + ++ + ++ NF +F F I+E+ + D+ A
Sbjct: 229 FPAFSKEPMTKADLE-QCWDIPNFFQLFCNFSVSIYESVSETITKMLKAIEDLPKQDKAP 287
Query: 268 QHPPTEFIREGDDDRTVCREIRHNSTGCLRMKDQCDKCREILSVDCSTNNPSQAKLRREL 327
H DR +C E+ N + C + ++C KC+ LS DC P L EL
Sbjct: 288 DHGGLISKMLPGQDRGLCGELDQNLSRCFKFHEKCQKCQAHLSEDC----PDVPALHTEL 343
Query: 328 DESLQVAERLTRKYNELLKSYQWKMLNTSSLLEQLNEQFNWVSRLANLTQGEDQYYLRVT 387
DE++++ ++Y ++L+ + + +T+ L+E++ QF WVS LAN + + +
Sbjct: 344 DEAIRLVNVSNQQYGQILQMTRKHLEDTAYLVEKMRGQFGWVSELANQAPETEIIFNSIQ 403
Query: 388 TVAS-HTSDSDVPSGVTEVVVKLFDSDPITVTVPVEVSRKNPKFMETVAEKALQEYRK 444
V H + + + S T+ +P+E S ++ F+ V KALQ +++
Sbjct: 404 VVPRIHEGNISKQDETMMTDLSILPSSNFTLKIPLEESAESSNFIGYVVAKALQHFKE 461
>gi|7657490 clusterin-like 1 (retinal) [Homo sapiens]
Length = 466
Score = 156 bits (395), Expect = 3e-38
Identities = 122/478 (25%), Positives = 219/478 (45%), Gaps = 51/478 (10%)
Query: 1 MMKTLLLFVGLLL---------TWESGQVLGDQTVSDNELQEMSNQGSKYVNKEIQNAVN 51
M LL+F+ LL TW+ D+T L+ S G ++E++ A+
Sbjct: 1 MKPPLLVFIVCLLWLKDSHCAPTWK------DKTAISENLKSFSEVGEIDADEEVKKALT 54
Query: 52 GVKQIKTLIEKTNEERKTLLSNLEEAKKKKEDALNETRESETKLKELPGVCNETMMALWE 111
G+KQ+K ++E+ +E L+S L++ +++K++AL E + L+E +C E++ W
Sbjct: 55 GIKQMKIMMERKEKEHTNLMSTLKKCREEKQEALKLLNEVQEHLEEEERLCRESLADSWG 114
Query: 112 ECKPCLKQTCMKFYARVCRSGSGLVGRQLEEFLNQSSPFYFWMNGDR------IDSLLEN 165
EC+ CL+ CM+ Y C+ V ++E F + F F + D + L+E
Sbjct: 115 ECRSCLENNCMRIYT-TCQPSWSSVKNKIERFFRKIYQFLFPFHEDNEKDLPISEKLIEE 173
Query: 166 DRQQTHMLDVMQDHFSRASSIIDELFQDRF-FTREPQDTY------HYLPFSLPHRRPHF 218
D Q T M DV FS+ + ++ LF F R+ Q + H++ P+F
Sbjct: 174 DAQLTQMEDV----FSQLTVDVNSLFNRSFNVFRQMQQEFDQTFQSHFIS-DTDLTEPYF 228
Query: 219 F--FPKSRIVRSLMPFSPYEPLNFHAMFQPFLEMIHEA---------QQAMDIHFHSPAF 267
F F K + ++ + ++ NF +F F I+E+ + D+ A
Sbjct: 229 FPAFSKEPMTKADLE-QCWDIPNFFQLFCNFSVSIYESVSETITKMLKAIEDLPKQDKAP 287
Query: 268 QHPPTEFIREGDDDRTVCREIRHNSTGCLRMKDQCDKCREILSVDCSTNNPSQAKLRREL 327
H DR +C E+ N + C + ++C KC+ LS DC P L EL
Sbjct: 288 DHGGLISKMLPGQDRGLCGELDQNLSRCFKFHEKCQKCQAHLSEDC----PDVPALHTEL 343
Query: 328 DESLQVAERLTRKYNELLKSYQWKMLNTSSLLEQLNEQFNWVSRLANLTQGEDQYYLRVT 387
DE++++ ++Y ++L+ + + +T+ L+E++ QF WVS LAN + + +
Sbjct: 344 DEAIRLVNVSNQQYGQILQMTRKHLEDTAYLVEKMRGQFGWVSELANQAPETEIIFNSIQ 403
Query: 388 TVAS-HTSDSDVPSGVTEVVVKLFDSDPITVTVPVEVSRKNPKFMETVAEKALQEYRK 444
V H + + + S T+ +P+E S ++ F+ V KALQ +++
Sbjct: 404 VVPRIHEGNISKQDETMMTDLSILPSSNFTLKIPLEESAESSNFIGYVVAKALQHFKE 461
>gi|118498356 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 37.0 bits (84), Expect = 0.036
Identities = 27/101 (26%), Positives = 47/101 (46%), Gaps = 12/101 (11%)
Query: 19 QVLGDQTVSDNELQEMSNQGSKYVNKEIQNAVNGVKQIKTLIEKTNEERKTLLSNLEEAK 78
Q+ T S+ EL+ + ++ NK+I+N + ++ +EK ER T ++ + E K
Sbjct: 1177 QMQSSFTSSEQELERLRSE-----NKDIENLRREREHLEMELEKAEMERSTYVTEVRELK 1231
Query: 79 -------KKKEDALNETRESETKLKELPGVCNETMMALWEE 112
KK +D+ +E +L L NET+ L E
Sbjct: 1232 DLLTELQKKLDDSYSEAVRQNEELNLLKAQLNETLTKLRTE 1272
>gi|33620775 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 37.0 bits (84), Expect = 0.036
Identities = 27/101 (26%), Positives = 47/101 (46%), Gaps = 12/101 (11%)
Query: 19 QVLGDQTVSDNELQEMSNQGSKYVNKEIQNAVNGVKQIKTLIEKTNEERKTLLSNLEEAK 78
Q+ T S+ EL+ + ++ NK+I+N + ++ +EK ER T ++ + E K
Sbjct: 1177 QMQSSFTSSEQELERLRSE-----NKDIENLRREREHLEMELEKAEMERSTYVTEVRELK 1231
Query: 79 -------KKKEDALNETRESETKLKELPGVCNETMMALWEE 112
KK +D+ +E +L L NET+ L E
Sbjct: 1232 DLLTELQKKLDDSYSEAVRQNEELNLLKAQLNETLTKLRTE 1272
>gi|7705682 geminin [Homo sapiens]
Length = 209
Score = 36.2 bits (82), Expect = 0.062
Identities = 25/90 (27%), Positives = 39/90 (43%), Gaps = 8/90 (8%)
Query: 28 DNELQEMSNQGSKYVNKEIQNAVNGVKQIKTLIEKTNEERKTLLSNLEEAKKKKEDALNE 87
DNE+ + + NKE+ V+ + LIE+ N E L N E ++ D+ E
Sbjct: 128 DNEIARLKKE-----NKELAEVAEHVQYMAELIERLNGEP---LDNFESLDNQEFDSEEE 179
Query: 88 TRESETKLKELPGVCNETMMALWEECKPCL 117
T E G C E ++ + KPC+
Sbjct: 180 TVEDSLVEDSEIGTCAEGTVSSSTDAKPCI 209
>gi|111955162 5-azacytidine induced 1 isoform b [Homo sapiens]
Length = 1044
Score = 36.2 bits (82), Expect = 0.062
Identities = 23/83 (27%), Positives = 43/83 (51%), Gaps = 2/83 (2%)
Query: 15 WESGQVLGDQTVSDNELQEMSNQGSKYVNKEIQNAVNGVKQIKTLIEKTNEERKTLLSNL 74
WE+G+ ++ N QE+ + K +KEI+ ++ ++ L ++ E K S +
Sbjct: 830 WEAGRTRKEEAWLLNREQELREEIRKGRDKEIELVIHRLEADMALAKE--ESEKAAESRI 887
Query: 75 EEAKKKKEDALNETRESETKLKE 97
+ + K E L+E +SE KL+E
Sbjct: 888 KRLRDKYEAELSELEQSERKLQE 910
>gi|111955084 5-azacytidine induced 1 isoform a [Homo sapiens]
Length = 1080
Score = 36.2 bits (82), Expect = 0.062
Identities = 23/83 (27%), Positives = 43/83 (51%), Gaps = 2/83 (2%)
Query: 15 WESGQVLGDQTVSDNELQEMSNQGSKYVNKEIQNAVNGVKQIKTLIEKTNEERKTLLSNL 74
WE+G+ ++ N QE+ + K +KEI+ ++ ++ L ++ E K S +
Sbjct: 866 WEAGRTRKEEAWLLNREQELREEIRKGRDKEIELVIHRLEADMALAKE--ESEKAAESRI 923
Query: 75 EEAKKKKEDALNETRESETKLKE 97
+ + K E L+E +SE KL+E
Sbjct: 924 KRLRDKYEAELSELEQSERKLQE 946
>gi|118498362 kinectin 1 isoform b [Homo sapiens]
Length = 1306
Score = 35.8 bits (81), Expect = 0.081
Identities = 20/91 (21%), Positives = 46/91 (50%), Gaps = 5/91 (5%)
Query: 19 QVLGDQTVSDNELQEMSNQGSKYVNKEIQNAVNGVKQIKTLIEKTNEERKTLLSNLEEAK 78
Q+ T S+ EL+ + ++ NK+I+N + ++ +EK ER T ++ + E K
Sbjct: 1154 QMQSSFTSSEQELERLRSE-----NKDIENLRREREHLEMELEKAEMERSTYVTEVRELK 1208
Query: 79 KKKEDALNETRESETKLKELPGVCNETMMAL 109
+ + L + R + + +++ G ++ +L
Sbjct: 1209 AQLNETLTKLRTEQNERQKVAGDLHKAQQSL 1239
>gi|118498368 kinectin 1 isoform c [Homo sapiens]
Length = 1300
Score = 35.8 bits (81), Expect = 0.081
Identities = 20/91 (21%), Positives = 46/91 (50%), Gaps = 5/91 (5%)
Query: 19 QVLGDQTVSDNELQEMSNQGSKYVNKEIQNAVNGVKQIKTLIEKTNEERKTLLSNLEEAK 78
Q+ T S+ EL+ + ++ NK+I+N + ++ +EK ER T ++ + E K
Sbjct: 1148 QMQSSFTSSEQELERLRSE-----NKDIENLRREREHLEMELEKAEMERSTYVTEVRELK 1202
Query: 79 KKKEDALNETRESETKLKELPGVCNETMMAL 109
+ + L + R + + +++ G ++ +L
Sbjct: 1203 AQLNETLTKLRTEQNERQKVAGDLHKAQQSL 1233
>gi|9910266 kinesin family member 15 [Homo sapiens]
Length = 1388
Score = 35.4 bits (80), Expect = 0.11
Identities = 87/408 (21%), Positives = 167/408 (40%), Gaps = 50/408 (12%)
Query: 19 QVLGDQTVSDNELQEMSNQGSKYVNKEIQNAVNGVKQIKTLIEKTNEERKTLLSNLEE-- 76
++L + +N+L + + +KEI + V+Q K E++ + LEE
Sbjct: 904 ELLEAEKERNNKLSLQFEEDKENSSKEILKVLEAVRQEKQKETAKCEQQMAKVQKLEESL 963
Query: 77 -AKKKKEDALNETRESETK--------LKEL-PGVC--NETMMALWEECKPCLKQTCMKF 124
A +K +L ++R+S+ K ++EL VC ET+ L +E K C
Sbjct: 964 LATEKVISSLEKSRDSDKKVVADLMNQIQELRTSVCEKTETIDTLKQELKDI---NCKYN 1020
Query: 125 YARVCRSGSG-LVGRQLEEFLNQSSPFYFWMNGDRI--DSLLENDRQQTHMLDVMQDHFS 181
A V R S L+ +Q + L+ + + I D L E+ T L+++ +
Sbjct: 1021 SALVDREESRVLIKKQEVDILDLKETLRLRILSEDIERDMLCEDLAHATEQLNMLTEASK 1080
Query: 182 RASSII----DELFQDRFFTREPQDTYHYLPFSLPHRRPHFFFPKSRIVRSLM------P 231
+ S ++ +EL + +E Q + + ++ + F K R + +M P
Sbjct: 1081 KHSGLLQSAQEELTKKEALIQELQHKLNQKKEEVEQKKNEYNF-KMRQLEHVMDSAAEDP 1139
Query: 232 FSPYEPLNFHAMFQPFLEMIHEAQQAMDIHFHSPAFQHPPTEFIREGDDDRTVCREIRHN 291
SP P +F LE + Q+ D + +H T+ ++DR V
Sbjct: 1140 QSPKTPPHFQTHLAKLLET--QEQEIEDGRASKTSLEHLVTKL----NEDREV------K 1187
Query: 292 STGCLRMKDQCDKCREILSVDCSTNNPSQAKLRRELDESLQVAERLTRKY--NELLKSYQ 349
+ LRMK+Q + E L ++ L+ +LD+ + E + + N+ LK+ Q
Sbjct: 1188 NAEILRMKEQLRE-MENLRLESQQLIEKNWLLQGQLDDIKRQKENSDQNHPDNQQLKNEQ 1246
Query: 350 ----WKMLNTSSLLEQLNEQFNWVSRLANLTQGEDQYYLRVTTVASHT 393
+ L S ++E++ + + + + ++ LR+T T
Sbjct: 1247 EESIKERLAKSKIVEEMLKMKADLEEVQSALYNKEMECLRMTDEVERT 1294
>gi|47174859 tripartite motif-containing 46 [Homo sapiens]
Length = 759
Score = 35.4 bits (80), Expect = 0.11
Identities = 28/124 (22%), Positives = 54/124 (43%), Gaps = 2/124 (1%)
Query: 13 LTWESGQVLGDQTVSDNELQEMSNQGSKYVNKEIQNAVNGVKQ-IKTLIEKTNEERKTLL 71
LT +LG+Q ++ E+ + ++ Q A V Q ++ L E+R +LL
Sbjct: 274 LTKSLTYILGNQDTVQTQICELE-EAVRHTEVSGQQAKEEVSQLVRGLGAVLEEKRASLL 332
Query: 72 SNLEEAKKKKEDALNETRESETKLKELPGVCNETMMALWEECKPCLKQTCMKFYARVCRS 131
+EE ++++ L+ + L + G+ L E +PC Q + + R+ R+
Sbjct: 333 QAIEECQQERLARLSAQIQEHRSLLDGSGLVGYAQEVLKETDQPCFVQAAKQLHNRIARA 392
Query: 132 GSGL 135
L
Sbjct: 393 TEAL 396
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 35.0 bits (79), Expect = 0.14
Identities = 69/367 (18%), Positives = 153/367 (41%), Gaps = 44/367 (11%)
Query: 33 EMSNQGSKYVNKEIQNAVNGVKQIKTLIEKTNEERKTLLS--NLEEAKKKKEDALNETRE 90
E+ NQ +Y K + +Q+K EKT E K+ L+ +++ + E+ L + +
Sbjct: 970 ELQNQLDEYKEKNRRELAEMQRQLK---EKTLEAEKSRLTAMKMQDEMRLMEEELRDYQR 1026
Query: 91 SETKLKELPGVCNETMMALWEECKPCLKQTCMKFYARVCRSGSGLVGRQLEEFLNQSSPF 150
++ + + +T+ L E + K + + RS + +Q+E+ ++Q
Sbjct: 1027 AQDEALTKRQLLEQTLKDLEYELEA-------KSHLKDDRSR---LVKQMEDKVSQ---- 1072
Query: 151 YFWMNGDRIDSLLENDRQQTHMLDVMQDHFSRASSIIDELFQDRFFTREPQDTYHYLPFS 210
++ LE +R + D++ + SR+ +++L + R + S
Sbjct: 1073 --------LEMELEEERNNS---DLLSERISRSREQMEQLRNELLQERAARQDLECDKIS 1121
Query: 211 LPHRRPHFFFPKSRIVRSLMPFSPYEP---LNFHAMFQPFLEMIH-EAQQAMDIHFHSPA 266
L + KSRI+ + + + A + + E + ++ +
Sbjct: 1122 LERQNKDL---KSRIIHLEGSYRSSKEGLVVQMEARIAELEDRLESEERDRANLQLSNRR 1178
Query: 267 FQHPPTEFIREGDDDRTVCREIRHNSTGCLR-MKDQCDKCREILSVDCSTNNPSQAKLRR 325
+ E + + DD+ + + + L+ MK Q ++ E + S+ KL+R
Sbjct: 1179 LERKVKELVMQVDDEHLSLTDQKDQLSLRLKAMKRQVEEAEE----EIDRLESSKKKLQR 1234
Query: 326 ELDESLQVAERLTRKYNELLKSYQWKMLNTSSLLEQLNEQFNWVSRLANLTQGEDQY-YL 384
EL+E + + E L + N + K + K L S +L+ +++ + + +L + Y +
Sbjct: 1235 ELEEQMDMNEHLQGQLNSMKKDLRLKKL-PSKVLDDMDDDDDLSTDGGSLYEAPVSYTFS 1293
Query: 385 RVTTVAS 391
+ +TVAS
Sbjct: 1294 KDSTVAS 1300
Score = 31.2 bits (69), Expect = 2.0
Identities = 21/91 (23%), Positives = 45/91 (49%), Gaps = 13/91 (14%)
Query: 27 SDNELQEMSNQGSKY------VNKEIQNAVNGVKQIKTLIEKTNEERKTLLSNLEEAKKK 80
S +E++++ Q SK + +++Q V + IK EER+ + +NLEE + +
Sbjct: 605 STSEVKDLLEQKSKLTIEVAELQRQLQLEVKNQQNIK-------EERERMRANLEELRSQ 657
Query: 81 KEDALNETRESETKLKELPGVCNETMMALWE 111
+ + E + +L+E G + + L++
Sbjct: 658 HNEKVEENSTLQQRLEESEGELRKNLEELFQ 688
>gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo
sapiens]
Length = 1591
Score = 34.7 bits (78), Expect = 0.18
Identities = 22/61 (36%), Positives = 37/61 (60%), Gaps = 4/61 (6%)
Query: 51 NGVKQIKTLIEKTNEER--KTLLSNLEEAKKKKEDALNETRESETKLKELPG--VCNETM 106
N ++++K +E T +E+ K LLS E + K + + ET E+E K+K+L G VC E +
Sbjct: 846 NIIEKVKCSLEITLKEKHQKELLSLKNEYEGKLDGLIKETEENENKIKKLKGELVCLEEV 905
Query: 107 M 107
+
Sbjct: 906 L 906
>gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo
sapiens]
Length = 1594
Score = 34.7 bits (78), Expect = 0.18
Identities = 22/61 (36%), Positives = 37/61 (60%), Gaps = 4/61 (6%)
Query: 51 NGVKQIKTLIEKTNEER--KTLLSNLEEAKKKKEDALNETRESETKLKELPG--VCNETM 106
N ++++K +E T +E+ K LLS E + K + + ET E+E K+K+L G VC E +
Sbjct: 846 NIIEKVKCSLEITLKEKHQKELLSLKNEYEGKLDGLIKETEENENKIKKLKGELVCLEEV 905
Query: 107 M 107
+
Sbjct: 906 L 906
>gi|239745140 PREDICTED: similar to hect domain and RLD 2 [Homo
sapiens]
Length = 1052
Score = 34.7 bits (78), Expect = 0.18
Identities = 26/93 (27%), Positives = 44/93 (47%), Gaps = 9/93 (9%)
Query: 294 GCLRMKDQC-DKCREILSV-------DCSTNNPSQAKLRRELDESLQVAERLTRKYNELL 345
GCL+ QC + LS + S ++ S+A EL++SLQ RL +L
Sbjct: 207 GCLQYSLQCIGELERALSAVTTTEEKEISFSSRSRAHTEWELEQSLQEKARLKAXLTQLK 266
Query: 346 KSYQWKMLNTSSLLEQL-NEQFNWVSRLANLTQ 377
+S+Q L + +Q+ E+ W R+ ++Q
Sbjct: 267 ESFQQVQLQRDNYAQQIKGERARWQQRMRKMSQ 299
>gi|51479166 bicaudal D homolog 2 isoform 1 [Homo sapiens]
Length = 855
Score = 34.7 bits (78), Expect = 0.18
Identities = 22/81 (27%), Positives = 38/81 (46%)
Query: 58 TLIEKTNEERKTLLSNLEEAKKKKEDALNETRESETKLKELPGVCNETMMALWEECKPCL 117
+L+EK + + + LL+ LE+ KK D ET+ S + ++ +E + L+ C
Sbjct: 486 SLLEKASRQDRELLARLEKELKKVSDVAGETQGSLSVAQDELVTFSEELANLYHHVCMCN 545
Query: 118 KQTCMKFYARVCRSGSGLVGR 138
+T + R G G GR
Sbjct: 546 NETPNRVMLDYYREGQGGAGR 566
>gi|38683807 ankyrin repeat domain protein 17 isoform a [Homo
sapiens]
Length = 2603
Score = 34.7 bits (78), Expect = 0.18
Identities = 19/65 (29%), Positives = 39/65 (60%), Gaps = 1/65 (1%)
Query: 34 MSNQGSKYVNKEIQNAVNGVKQ-IKTLIEKTNEERKTLLSNLEEAKKKKEDALNETRESE 92
++NQ + + +E Q + ++Q IK IEK + + L++ ++ K+K + LN+TRE +
Sbjct: 799 ITNQSPESIVEEAQGKLTELEQRIKEAIEKNAQLQSLELAHADQLTKEKIEELNKTREEQ 858
Query: 93 TKLKE 97
+ K+
Sbjct: 859 IQKKQ 863
>gi|21735417 bicaudal D homolog 2 isoform 2 [Homo sapiens]
Length = 824
Score = 34.7 bits (78), Expect = 0.18
Identities = 22/81 (27%), Positives = 38/81 (46%)
Query: 58 TLIEKTNEERKTLLSNLEEAKKKKEDALNETRESETKLKELPGVCNETMMALWEECKPCL 117
+L+EK + + + LL+ LE+ KK D ET+ S + ++ +E + L+ C
Sbjct: 486 SLLEKASRQDRELLARLEKELKKVSDVAGETQGSLSVAQDELVTFSEELANLYHHVCMCN 545
Query: 118 KQTCMKFYARVCRSGSGLVGR 138
+T + R G G GR
Sbjct: 546 NETPNRVMLDYYREGQGGAGR 566
>gi|38570058 hypothetical protein LOC80129 [Homo sapiens]
Length = 715
Score = 34.3 bits (77), Expect = 0.24
Identities = 34/114 (29%), Positives = 56/114 (49%), Gaps = 13/114 (11%)
Query: 14 TWESGQVLGDQTVSDNELQEMSNQGSKY---VNKEIQNAVNGVKQIK----TLIEKTNEE 66
T E + + D S ++L++M + K V E+ + K+ K +IE E
Sbjct: 573 TLEQTKAIEDLNKSRDQLEKMKEKAEKKLMSVKSELDTTEHEAKENKERARNMIEVVTSE 632
Query: 67 RKTLLSNLEEAKKKKEDALNETRESETKLKELPGVCNETMMALWE-ECKPCLKQ 119
KTL +LEEA +K+E L + RE +++ L N T +AL + E CL++
Sbjct: 633 MKTLKKSLEEA-EKREKQLADFREVVSQMLGL----NVTSLALPDYEIIKCLER 681
>gi|19924131 RAD50 homolog isoform 2 [Homo sapiens]
Length = 1173
Score = 34.3 bits (77), Expect = 0.24
Identities = 24/83 (28%), Positives = 44/83 (53%), Gaps = 12/83 (14%)
Query: 19 QVLGDQTVS-DNELQEMSNQGSKYVNKEIQNAVNGVKQIKTLIEKTNEERKTLLSNLEEA 77
Q L +QTV E+Q + +EI++A V ++T +EK +E++ L++ +
Sbjct: 746 QQLEEQTVELSTEVQSLY--------REIKDAKEQVSPLETTLEKFQQEKEELINKKNTS 797
Query: 78 KKKKEDALNETRESETKLKELPG 100
K +D LN+ +E K+K + G
Sbjct: 798 NKIAQDKLNDIKE---KVKNIHG 817
>gi|19924129 RAD50 homolog isoform 1 [Homo sapiens]
Length = 1312
Score = 34.3 bits (77), Expect = 0.24
Identities = 24/83 (28%), Positives = 44/83 (53%), Gaps = 12/83 (14%)
Query: 19 QVLGDQTVS-DNELQEMSNQGSKYVNKEIQNAVNGVKQIKTLIEKTNEERKTLLSNLEEA 77
Q L +QTV E+Q + +EI++A V ++T +EK +E++ L++ +
Sbjct: 885 QQLEEQTVELSTEVQSLY--------REIKDAKEQVSPLETTLEKFQQEKEELINKKNTS 936
Query: 78 KKKKEDALNETRESETKLKELPG 100
K +D LN+ +E K+K + G
Sbjct: 937 NKIAQDKLNDIKE---KVKNIHG 956
>gi|154689866 hypothetical protein LOC9778 [Homo sapiens]
Length = 1395
Score = 34.3 bits (77), Expect = 0.24
Identities = 33/125 (26%), Positives = 50/125 (40%), Gaps = 23/125 (18%)
Query: 11 LLLTWESGQVL----GDQTVSDNELQEMSNQGSKYVNKEIQNAVNGVKQIKTLIEKTNEE 66
+ L WE G + SD L+EM Q + + + +G I+TL+E+
Sbjct: 81 IFLGWEKGAYKKWGKSKKKCSDLTLEEMKKQAAVQCLRSASDESSG---IETLVEELCSR 137
Query: 67 RKTLLSNLEEAKKKK---------------EDALNETRESETKLKELPGVCNETMMALWE 111
K L S EE KK +D + E+ L E P VC + +M +W
Sbjct: 138 LKDLQSKQEEKIHKKLEGSPSPEAELSPPAKDQVEMYYEAFPPLSEKP-VCLQEIMTVWN 196
Query: 112 ECKPC 116
+ K C
Sbjct: 197 KSKVC 201
>gi|154689751 hypothetical protein LOC9778 [Homo sapiens]
Length = 1395
Score = 34.3 bits (77), Expect = 0.24
Identities = 33/125 (26%), Positives = 50/125 (40%), Gaps = 23/125 (18%)
Query: 11 LLLTWESGQVL----GDQTVSDNELQEMSNQGSKYVNKEIQNAVNGVKQIKTLIEKTNEE 66
+ L WE G + SD L+EM Q + + + +G I+TL+E+
Sbjct: 81 IFLGWEKGAYKKWGKSKKKCSDLTLEEMKKQAAVQCLRSASDESSG---IETLVEELCSR 137
Query: 67 RKTLLSNLEEAKKKK---------------EDALNETRESETKLKELPGVCNETMMALWE 111
K L S EE KK +D + E+ L E P VC + +M +W
Sbjct: 138 LKDLQSKQEEKIHKKLEGSPSPEAELSPPAKDQVEMYYEAFPPLSEKP-VCLQEIMTVWN 196
Query: 112 ECKPC 116
+ K C
Sbjct: 197 KSKVC 201
>gi|93102364 SWAP-70 protein [Homo sapiens]
Length = 585
Score = 33.9 bits (76), Expect = 0.31
Identities = 30/89 (33%), Positives = 44/89 (49%), Gaps = 13/89 (14%)
Query: 15 WESGQVLGDQTVSDNELQEMSNQGSKYVNKE--IQNAVNGVKQIKTLIEKTNEERKTLLS 72
W Q QT ++ E QE+ NQ V KE +Q A+ ++Q++ ERK L
Sbjct: 467 WHLEQQQAIQT-TEAEKQELENQR---VLKEQALQEAMEQLEQLEL-------ERKQALE 515
Query: 73 NLEEAKKKKEDALNETRESETKLKELPGV 101
EE KKK E A N+T+ + K+ G+
Sbjct: 516 QYEEVKKKLEMATNKTKSWKDKVAHHEGL 544
>gi|22027627 TNF receptor-associated factor 5 [Homo sapiens]
Length = 557
Score = 33.9 bits (76), Expect = 0.31
Identities = 25/76 (32%), Positives = 42/76 (55%), Gaps = 8/76 (10%)
Query: 31 LQEMSNQGSKYVNKEIQNAVNGVKQIKTLIEKTNEERKTLLSNLEEAKKKKEDALN---- 86
LQ ++ Q +K+ + + AV+ VKQ TL+E N++R L+ LEE K + +N
Sbjct: 330 LQMVNQQQNKFDLRPLMEAVDTVKQKITLLE-NNDQR---LAVLEEETNKHDTHINIHKA 385
Query: 87 ETRESETKLKELPGVC 102
+ ++E + K L G C
Sbjct: 386 QLSKNEERFKLLEGTC 401
>gi|77404348 TNF receptor-associated factor 5 [Homo sapiens]
Length = 557
Score = 33.9 bits (76), Expect = 0.31
Identities = 25/76 (32%), Positives = 42/76 (55%), Gaps = 8/76 (10%)
Query: 31 LQEMSNQGSKYVNKEIQNAVNGVKQIKTLIEKTNEERKTLLSNLEEAKKKKEDALN---- 86
LQ ++ Q +K+ + + AV+ VKQ TL+E N++R L+ LEE K + +N
Sbjct: 330 LQMVNQQQNKFDLRPLMEAVDTVKQKITLLE-NNDQR---LAVLEEETNKHDTHINIHKA 385
Query: 87 ETRESETKLKELPGVC 102
+ ++E + K L G C
Sbjct: 386 QLSKNEERFKLLEGTC 401
>gi|11321603 TNF receptor-associated factor 5 [Homo sapiens]
Length = 557
Score = 33.9 bits (76), Expect = 0.31
Identities = 25/76 (32%), Positives = 42/76 (55%), Gaps = 8/76 (10%)
Query: 31 LQEMSNQGSKYVNKEIQNAVNGVKQIKTLIEKTNEERKTLLSNLEEAKKKKEDALN---- 86
LQ ++ Q +K+ + + AV+ VKQ TL+E N++R L+ LEE K + +N
Sbjct: 330 LQMVNQQQNKFDLRPLMEAVDTVKQKITLLE-NNDQR---LAVLEEETNKHDTHINIHKA 385
Query: 87 ETRESETKLKELPGVC 102
+ ++E + K L G C
Sbjct: 386 QLSKNEERFKLLEGTC 401
>gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 33.9 bits (76), Expect = 0.31
Identities = 26/88 (29%), Positives = 44/88 (50%), Gaps = 6/88 (6%)
Query: 16 ESGQVLGDQTVSD---NELQEMSNQGSKYVNKEIQNAVNGVKQIKTLIEKTNEERKTLLS 72
+SG+V+ D++ + ++++ ++ E + KQ K L E+ EE+K L
Sbjct: 436 QSGKVIPDRSTKPVVFSPTLMLTDEEKARIHAETALLMEKNKQEKELRERQQEEQKEKLR 495
Query: 73 NLEE---AKKKKEDALNETRESETKLKE 97
E+ AKKK+E NE E + K KE
Sbjct: 496 KEEQEQKAKKKQEAEENEITEKQQKAKE 523
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.132 0.389
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,809,196
Number of Sequences: 37866
Number of extensions: 750460
Number of successful extensions: 4167
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 69
Number of HSP's successfully gapped in prelim test: 113
Number of HSP's that attempted gapping in prelim test: 3729
Number of HSP's gapped (non-prelim): 549
length of query: 449
length of database: 18,247,518
effective HSP length: 106
effective length of query: 343
effective length of database: 14,233,722
effective search space: 4882166646
effective search space used: 4882166646
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.