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Search of human proteins with 126116596
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|126116596 asp (abnormal spindle)-like, microcephaly
associated [Homo sapiens]
(3477 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|126116596 asp (abnormal spindle)-like, microcephaly associate... 6863 0.0
gi|215982794 myosin VA isoform 2 [Homo sapiens] 81 2e-14
gi|215982791 myosin VA isoform 1 [Homo sapiens] 81 2e-14
gi|156119615 myosin IXA [Homo sapiens] 77 4e-13
gi|122937345 myosin VB [Homo sapiens] 76 7e-13
gi|153945715 myosin VC [Homo sapiens] 71 2e-11
gi|189083802 myosin VIIA isoform 2 [Homo sapiens] 64 2e-09
gi|189083800 myosin VIIA isoform 3 [Homo sapiens] 64 2e-09
gi|189083798 myosin VIIA isoform 1 [Homo sapiens] 64 2e-09
gi|122937512 myosin VIIB [Homo sapiens] 64 3e-09
gi|169218211 PREDICTED: similar to plectin 1, partial [Homo sapi... 62 8e-09
gi|54112401 calmodulin-binding transcription activator 1 [Homo s... 62 8e-09
gi|112382252 spectrin, beta, non-erythrocytic 1 isoform 2 [Homo ... 60 5e-08
gi|112382250 spectrin, beta, non-erythrocytic 1 isoform 1 [Homo ... 60 5e-08
gi|194272142 myosin IXB isoform 2 [Homo sapiens] 59 6e-08
gi|33356170 myosin IXB isoform 1 [Homo sapiens] 59 6e-08
gi|194328685 myosin IB isoform 1 [Homo sapiens] 59 8e-08
gi|240120050 myosin IB isoform 1 [Homo sapiens] 59 8e-08
gi|29826341 calmodulin binding transcription activator 2 [Homo s... 57 2e-07
gi|5032281 dystrophin Dp427c isoform [Homo sapiens] 57 3e-07
gi|5032287 dystrophin Dp427p1 isoform [Homo sapiens] 57 3e-07
gi|5032283 dystrophin Dp427m isoform [Homo sapiens] 57 3e-07
gi|110611228 utrophin [Homo sapiens] 57 3e-07
gi|44889481 myosin IB isoform 2 [Homo sapiens] 56 7e-07
gi|170014684 IQ motif containing B1 isoform a [Homo sapiens] 55 9e-07
gi|154354979 myosin X [Homo sapiens] 55 2e-06
gi|39753961 IQ motif containing GTPase activating protein 3 [Hom... 55 2e-06
gi|115430237 spectrin, beta, non-erythrocytic 4 isoform sigma1 [... 54 2e-06
gi|5902122 spectrin, beta, non-erythrocytic 2 [Homo sapiens] 53 6e-06
gi|224451032 KIAA1683 isoform a [Homo sapiens] 52 8e-06
>gi|126116596 asp (abnormal spindle)-like, microcephaly associated
[Homo sapiens]
Length = 3477
Score = 6863 bits (17806), Expect = 0.0
Identities = 3477/3477 (100%), Positives = 3477/3477 (100%)
Query: 1 MANRRVGRGCWEVSPTERRPPAGLRGPAAEEEASSPPVLSLSHFCRSPFLCFGDVLLGAS 60
MANRRVGRGCWEVSPTERRPPAGLRGPAAEEEASSPPVLSLSHFCRSPFLCFGDVLLGAS
Sbjct: 1 MANRRVGRGCWEVSPTERRPPAGLRGPAAEEEASSPPVLSLSHFCRSPFLCFGDVLLGAS 60
Query: 61 RTLSLALDNPNEEVAEVKISHFPAADLGFSVSQRCFVLQPKEKIVISVNWTPLKEGRVRE 120
RTLSLALDNPNEEVAEVKISHFPAADLGFSVSQRCFVLQPKEKIVISVNWTPLKEGRVRE
Sbjct: 61 RTLSLALDNPNEEVAEVKISHFPAADLGFSVSQRCFVLQPKEKIVISVNWTPLKEGRVRE 120
Query: 121 IMTFLVNDVLKHQAILLGNAEEQKKKKRSLWDTIKKKKISASTSHNRRVSNIQNVNKTFS 180
IMTFLVNDVLKHQAILLGNAEEQKKKKRSLWDTIKKKKISASTSHNRRVSNIQNVNKTFS
Sbjct: 121 IMTFLVNDVLKHQAILLGNAEEQKKKKRSLWDTIKKKKISASTSHNRRVSNIQNVNKTFS 180
Query: 181 VSQKVDRVRSPLQACENLAMNEGGPPTENNSLILEENKIPISPISPAFNECHGATCLPLS 240
VSQKVDRVRSPLQACENLAMNEGGPPTENNSLILEENKIPISPISPAFNECHGATCLPLS
Sbjct: 181 VSQKVDRVRSPLQACENLAMNEGGPPTENNSLILEENKIPISPISPAFNECHGATCLPLS 240
Query: 241 VRRSTTYSSLHASENRELLNVHSANVSKVSFNEKAVTETSFNSVNVNGQRGENSKLSLTP 300
VRRSTTYSSLHASENRELLNVHSANVSKVSFNEKAVTETSFNSVNVNGQRGENSKLSLTP
Sbjct: 241 VRRSTTYSSLHASENRELLNVHSANVSKVSFNEKAVTETSFNSVNVNGQRGENSKLSLTP 300
Query: 301 NCSSTLNITQSQIHFLSPDSFVNNSHGANNELELVTCLSSDMFMKDNSQPVHLESTIAHE 360
NCSSTLNITQSQIHFLSPDSFVNNSHGANNELELVTCLSSDMFMKDNSQPVHLESTIAHE
Sbjct: 301 NCSSTLNITQSQIHFLSPDSFVNNSHGANNELELVTCLSSDMFMKDNSQPVHLESTIAHE 360
Query: 361 IYQKILSPDSFIKDNYGLNQDLESESVNPILSPNQFLKDNMAYMCTSQQTCKVPLSNENS 420
IYQKILSPDSFIKDNYGLNQDLESESVNPILSPNQFLKDNMAYMCTSQQTCKVPLSNENS
Sbjct: 361 IYQKILSPDSFIKDNYGLNQDLESESVNPILSPNQFLKDNMAYMCTSQQTCKVPLSNENS 420
Query: 421 QVPQSPEDWRKSEVSPRIPECQGSKSPKAIFEELVEMKSNYYSFIKQNNPKFSAVQDISS 480
QVPQSPEDWRKSEVSPRIPECQGSKSPKAIFEELVEMKSNYYSFIKQNNPKFSAVQDISS
Sbjct: 421 QVPQSPEDWRKSEVSPRIPECQGSKSPKAIFEELVEMKSNYYSFIKQNNPKFSAVQDISS 480
Query: 481 HSHNKQPKRRPILSATVTKRKATCTRENQTEINKPKAKRCLNSAVGEHEKVINNQKEKED 540
HSHNKQPKRRPILSATVTKRKATCTRENQTEINKPKAKRCLNSAVGEHEKVINNQKEKED
Sbjct: 481 HSHNKQPKRRPILSATVTKRKATCTRENQTEINKPKAKRCLNSAVGEHEKVINNQKEKED 540
Query: 541 FHSYLPIIDPILSKSKSYKNEVTPSSTTASVARKRKSDGSMEDANVRVAITEHTEVREIK 600
FHSYLPIIDPILSKSKSYKNEVTPSSTTASVARKRKSDGSMEDANVRVAITEHTEVREIK
Sbjct: 541 FHSYLPIIDPILSKSKSYKNEVTPSSTTASVARKRKSDGSMEDANVRVAITEHTEVREIK 600
Query: 601 RIHFSPSEPKTSAVKKTKNVTTPISKRISNREKLNLKKKTDLSIFRTPISKTNKRTKPII 660
RIHFSPSEPKTSAVKKTKNVTTPISKRISNREKLNLKKKTDLSIFRTPISKTNKRTKPII
Sbjct: 601 RIHFSPSEPKTSAVKKTKNVTTPISKRISNREKLNLKKKTDLSIFRTPISKTNKRTKPII 660
Query: 661 AVAQSSLTFIKPLKTDIPRHPMPFAAKNMFYDERWKEKQEQGFTWWLNFILTPDDFTVKT 720
AVAQSSLTFIKPLKTDIPRHPMPFAAKNMFYDERWKEKQEQGFTWWLNFILTPDDFTVKT
Sbjct: 661 AVAQSSLTFIKPLKTDIPRHPMPFAAKNMFYDERWKEKQEQGFTWWLNFILTPDDFTVKT 720
Query: 721 NISEVNAATLLLGIENQHKISVPRAPTKEEMSLRAYTARCRLNRLRRAACRLFTSEKMVK 780
NISEVNAATLLLGIENQHKISVPRAPTKEEMSLRAYTARCRLNRLRRAACRLFTSEKMVK
Sbjct: 721 NISEVNAATLLLGIENQHKISVPRAPTKEEMSLRAYTARCRLNRLRRAACRLFTSEKMVK 780
Query: 781 AIKKLEIEIEARRLIVRKDRHLWKDVGERQKVLNWLLSYNPLWLRIGLETTYGELISLED 840
AIKKLEIEIEARRLIVRKDRHLWKDVGERQKVLNWLLSYNPLWLRIGLETTYGELISLED
Sbjct: 781 AIKKLEIEIEARRLIVRKDRHLWKDVGERQKVLNWLLSYNPLWLRIGLETTYGELISLED 840
Query: 841 NSDVTGLAMFILNRLLWNPDIAAEYRHPTVPHLYRDGHEEALSKFTLKKLLLLVCFLDYA 900
NSDVTGLAMFILNRLLWNPDIAAEYRHPTVPHLYRDGHEEALSKFTLKKLLLLVCFLDYA
Sbjct: 841 NSDVTGLAMFILNRLLWNPDIAAEYRHPTVPHLYRDGHEEALSKFTLKKLLLLVCFLDYA 900
Query: 901 KISRLIDHDPCLFCKDAEFKASKEILLAFSRDFLSGEGDLSRHLGLLGLPVNHVQTPFDE 960
KISRLIDHDPCLFCKDAEFKASKEILLAFSRDFLSGEGDLSRHLGLLGLPVNHVQTPFDE
Sbjct: 901 KISRLIDHDPCLFCKDAEFKASKEILLAFSRDFLSGEGDLSRHLGLLGLPVNHVQTPFDE 960
Query: 961 FDFAVTNLAVDLQCGVRLVRTMELLTQNWDLSKKLRIPAISRLQKMHNVDIVLQVLKSRG 1020
FDFAVTNLAVDLQCGVRLVRTMELLTQNWDLSKKLRIPAISRLQKMHNVDIVLQVLKSRG
Sbjct: 961 FDFAVTNLAVDLQCGVRLVRTMELLTQNWDLSKKLRIPAISRLQKMHNVDIVLQVLKSRG 1020
Query: 1021 IELSDEHGNTILSKDIVDRHREKTLRLLWKIAFAFQVDISLNLDQLKEEIAFLKHTKSIK 1080
IELSDEHGNTILSKDIVDRHREKTLRLLWKIAFAFQVDISLNLDQLKEEIAFLKHTKSIK
Sbjct: 1021 IELSDEHGNTILSKDIVDRHREKTLRLLWKIAFAFQVDISLNLDQLKEEIAFLKHTKSIK 1080
Query: 1081 KTISLLSCHSDDLINKKKGKRDSGSFEQYSENIKLLMDWVNAVCAFYNKKVENFTVSFSD 1140
KTISLLSCHSDDLINKKKGKRDSGSFEQYSENIKLLMDWVNAVCAFYNKKVENFTVSFSD
Sbjct: 1081 KTISLLSCHSDDLINKKKGKRDSGSFEQYSENIKLLMDWVNAVCAFYNKKVENFTVSFSD 1140
Query: 1141 GRVLCYLIHHYHPCYVPFDAICQRTTQTVECTQTGSVVLNSSSESDDSSLDMSLKAFDHE 1200
GRVLCYLIHHYHPCYVPFDAICQRTTQTVECTQTGSVVLNSSSESDDSSLDMSLKAFDHE
Sbjct: 1141 GRVLCYLIHHYHPCYVPFDAICQRTTQTVECTQTGSVVLNSSSESDDSSLDMSLKAFDHE 1200
Query: 1201 NTSELYKELLENEKKNFHLVRSAVRDLGGIPAMINHSDMSNTIPDEKVVITYLSFLCARL 1260
NTSELYKELLENEKKNFHLVRSAVRDLGGIPAMINHSDMSNTIPDEKVVITYLSFLCARL
Sbjct: 1201 NTSELYKELLENEKKNFHLVRSAVRDLGGIPAMINHSDMSNTIPDEKVVITYLSFLCARL 1260
Query: 1261 LDLRKEIRAARLIQTTWRKYKLKTDLKRHQEREKAARIIQLAVINFLAKQRLRKRVNAAL 1320
LDLRKEIRAARLIQTTWRKYKLKTDLKRHQEREKAARIIQLAVINFLAKQRLRKRVNAAL
Sbjct: 1261 LDLRKEIRAARLIQTTWRKYKLKTDLKRHQEREKAARIIQLAVINFLAKQRLRKRVNAAL 1320
Query: 1321 VIQKYWRRVLAQRKLLMLKKEKLEKVQNKAASLIQGYWRRYSTRQRFLKLKYYSIILQSR 1380
VIQKYWRRVLAQRKLLMLKKEKLEKVQNKAASLIQGYWRRYSTRQRFLKLKYYSIILQSR
Sbjct: 1321 VIQKYWRRVLAQRKLLMLKKEKLEKVQNKAASLIQGYWRRYSTRQRFLKLKYYSIILQSR 1380
Query: 1381 IRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQRYEMLKSSTLIIQSMFRKWKQRKMQ 1440
IRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQRYEMLKSSTLIIQSMFRKWKQRKMQ
Sbjct: 1381 IRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQRYEMLKSSTLIIQSMFRKWKQRKMQ 1440
Query: 1441 SQVKATVILQRAFREWHLRKQAKEENSAIIIQSWYRMHKELRKYIYIRSCVVIIQKRFRC 1500
SQVKATVILQRAFREWHLRKQAKEENSAIIIQSWYRMHKELRKYIYIRSCVVIIQKRFRC
Sbjct: 1441 SQVKATVILQRAFREWHLRKQAKEENSAIIIQSWYRMHKELRKYIYIRSCVVIIQKRFRC 1500
Query: 1501 FQAQKLYKRRKESILTIQKYYKAYLKGKIERTNYLQKRAAAIQLQAAFRRLKAHNLCRQI 1560
FQAQKLYKRRKESILTIQKYYKAYLKGKIERTNYLQKRAAAIQLQAAFRRLKAHNLCRQI
Sbjct: 1501 FQAQKLYKRRKESILTIQKYYKAYLKGKIERTNYLQKRAAAIQLQAAFRRLKAHNLCRQI 1560
Query: 1561 RAACVIQSYWRMRQDRVRFLNLKKTIIKFQAHVRKHQQRQKYKKMKKAAVIIQTHFRAYI 1620
RAACVIQSYWRMRQDRVRFLNLKKTIIKFQAHVRKHQQRQKYKKMKKAAVIIQTHFRAYI
Sbjct: 1561 RAACVIQSYWRMRQDRVRFLNLKKTIIKFQAHVRKHQQRQKYKKMKKAAVIIQTHFRAYI 1620
Query: 1621 FAMKVLASYQKTRSAVIVLQSAYRGMQARKMYIHILTSVIKIQSYYRAYVSKKEFLSLKN 1680
FAMKVLASYQKTRSAVIVLQSAYRGMQARKMYIHILTSVIKIQSYYRAYVSKKEFLSLKN
Sbjct: 1621 FAMKVLASYQKTRSAVIVLQSAYRGMQARKMYIHILTSVIKIQSYYRAYVSKKEFLSLKN 1680
Query: 1681 ATIKLQSTVKMKQTRKQYLHLRAAALFIQQCYRSKKIAAQKREEYMQMRESCIKLQAFVR 1740
ATIKLQSTVKMKQTRKQYLHLRAAALFIQQCYRSKKIAAQKREEYMQMRESCIKLQAFVR
Sbjct: 1681 ATIKLQSTVKMKQTRKQYLHLRAAALFIQQCYRSKKIAAQKREEYMQMRESCIKLQAFVR 1740
Query: 1741 GYLVRKQMRLQRKAVISLQSYFRMRKARQYYLKMYKAIIVIQNYYHAYKAQVNQRKNFLQ 1800
GYLVRKQMRLQRKAVISLQSYFRMRKARQYYLKMYKAIIVIQNYYHAYKAQVNQRKNFLQ
Sbjct: 1741 GYLVRKQMRLQRKAVISLQSYFRMRKARQYYLKMYKAIIVIQNYYHAYKAQVNQRKNFLQ 1800
Query: 1801 VKKAATCLQAAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRVKYQSVLQSIIKIQRWYRA 1860
VKKAATCLQAAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRVKYQSVLQSIIKIQRWYRA
Sbjct: 1801 VKKAATCLQAAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRVKYQSVLQSIIKIQRWYRA 1860
Query: 1861 YKTLHDTRTHFLKTKAAVISLQSAYRGWKVRKQIRREHQAALKIQSAFRMAKAQKQFRLF 1920
YKTLHDTRTHFLKTKAAVISLQSAYRGWKVRKQIRREHQAALKIQSAFRMAKAQKQFRLF
Sbjct: 1861 YKTLHDTRTHFLKTKAAVISLQSAYRGWKVRKQIRREHQAALKIQSAFRMAKAQKQFRLF 1920
Query: 1921 KTAALVIQQNFRAWTAGRKQCMEYIELRHAVLVLQSMWKGKTLRRQLQRQHKCAIIIQSY 1980
KTAALVIQQNFRAWTAGRKQCMEYIELRHAVLVLQSMWKGKTLRRQLQRQHKCAIIIQSY
Sbjct: 1921 KTAALVIQQNFRAWTAGRKQCMEYIELRHAVLVLQSMWKGKTLRRQLQRQHKCAIIIQSY 1980
Query: 1981 YRMHVQQKKWKIMKKAALLIQKYYRAYSIGREQNHLYLKTKAAVVTLQSAYRGMKVRKRI 2040
YRMHVQQKKWKIMKKAALLIQKYYRAYSIGREQNHLYLKTKAAVVTLQSAYRGMKVRKRI
Sbjct: 1981 YRMHVQQKKWKIMKKAALLIQKYYRAYSIGREQNHLYLKTKAAVVTLQSAYRGMKVRKRI 2040
Query: 2041 KDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKITNHQHKEYLNLKKTAIKI 2100
KDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKITNHQHKEYLNLKKTAIKI
Sbjct: 2041 KDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKITNHQHKEYLNLKKTAIKI 2100
Query: 2101 QSVYRGIRVRRHIQHMHRAATFIKAMFKMHQSRISYHTMRKAAIVIQVRCRAYYQGKMQR 2160
QSVYRGIRVRRHIQHMHRAATFIKAMFKMHQSRISYHTMRKAAIVIQVRCRAYYQGKMQR
Sbjct: 2101 QSVYRGIRVRRHIQHMHRAATFIKAMFKMHQSRISYHTMRKAAIVIQVRCRAYYQGKMQR 2160
Query: 2161 EKYLTILKAVKVLQASFRGVRVRRTLRKMQTAATLIQSNYRRYRQQTYFNKLKKITKTVQ 2220
EKYLTILKAVKVLQASFRGVRVRRTLRKMQTAATLIQSNYRRYRQQTYFNKLKKITKTVQ
Sbjct: 2161 EKYLTILKAVKVLQASFRGVRVRRTLRKMQTAATLIQSNYRRYRQQTYFNKLKKITKTVQ 2220
Query: 2221 QRYWAMKERNIQFQRYNKLRHSVIYIQAIFRGKKARRHLKMMHIAATLIQRRFRTLMMRR 2280
QRYWAMKERNIQFQRYNKLRHSVIYIQAIFRGKKARRHLKMMHIAATLIQRRFRTLMMRR
Sbjct: 2221 QRYWAMKERNIQFQRYNKLRHSVIYIQAIFRGKKARRHLKMMHIAATLIQRRFRTLMMRR 2280
Query: 2281 RFLSLKKTAILIQRKYRAHLCTKHHLQFLQVQNAVIKIQSSYRRWMIRKRMREMHRAATF 2340
RFLSLKKTAILIQRKYRAHLCTKHHLQFLQVQNAVIKIQSSYRRWMIRKRMREMHRAATF
Sbjct: 2281 RFLSLKKTAILIQRKYRAHLCTKHHLQFLQVQNAVIKIQSSYRRWMIRKRMREMHRAATF 2340
Query: 2341 IQSTFRMHRLHMRYQALKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAFRGMKT 2400
IQSTFRMHRLHMRYQALKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAFRGMKT
Sbjct: 2341 IQSTFRMHRLHMRYQALKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAFRGMKT 2400
Query: 2401 RRHLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKHKLYQFLHLRKA 2460
RRHLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKHKLYQFLHLRKA
Sbjct: 2401 RRHLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKHKLYQFLHLRKA 2460
Query: 2461 AITIQSSYRRLMVKKKLQEMQRAAVLIQATFRMYRTYITFQTWKHASILIQQHYRTYRAA 2520
AITIQSSYRRLMVKKKLQEMQRAAVLIQATFRMYRTYITFQTWKHASILIQQHYRTYRAA
Sbjct: 2461 AITIQSSYRRLMVKKKLQEMQRAAVLIQATFRMYRTYITFQTWKHASILIQQHYRTYRAA 2520
Query: 2521 KLQRENYIRQWHSAVVIQAAYKGMKARQLLREKHKASIVIQSTYRMYRQYCFYQKLQWAT 2580
KLQRENYIRQWHSAVVIQAAYKGMKARQLLREKHKASIVIQSTYRMYRQYCFYQKLQWAT
Sbjct: 2521 KLQRENYIRQWHSAVVIQAAYKGMKARQLLREKHKASIVIQSTYRMYRQYCFYQKLQWAT 2580
Query: 2581 KIIQEKYRANKKKQKVFQHNELKKETCVQAGFQDMNIKKQIQEQHQAAIIIQKHCKAFKI 2640
KIIQEKYRANKKKQKVFQHNELKKETCVQAGFQDMNIKKQIQEQHQAAIIIQKHCKAFKI
Sbjct: 2581 KIIQEKYRANKKKQKVFQHNELKKETCVQAGFQDMNIKKQIQEQHQAAIIIQKHCKAFKI 2640
Query: 2641 RKHYLHLRATVVSIQRRYRKLTAVRTQAVICIQSYYRGFKVRKDIQNMHRAATLIQSFYR 2700
RKHYLHLRATVVSIQRRYRKLTAVRTQAVICIQSYYRGFKVRKDIQNMHRAATLIQSFYR
Sbjct: 2641 RKHYLHLRATVVSIQRRYRKLTAVRTQAVICIQSYYRGFKVRKDIQNMHRAATLIQSFYR 2700
Query: 2701 MHRAKVDYETKKTAIVVIQNYYRLYVRVKTERKNFLAVQKSVRTIQAAFRGMKVRQKLKN 2760
MHRAKVDYETKKTAIVVIQNYYRLYVRVKTERKNFLAVQKSVRTIQAAFRGMKVRQKLKN
Sbjct: 2701 MHRAKVDYETKKTAIVVIQNYYRLYVRVKTERKNFLAVQKSVRTIQAAFRGMKVRQKLKN 2760
Query: 2761 VSEEKMAAIVNQSALCCYRSKTQYEAVQSEGVMIQEWYKASGLACSQEAEYHSQSRAAVT 2820
VSEEKMAAIVNQSALCCYRSKTQYEAVQSEGVMIQEWYKASGLACSQEAEYHSQSRAAVT
Sbjct: 2761 VSEEKMAAIVNQSALCCYRSKTQYEAVQSEGVMIQEWYKASGLACSQEAEYHSQSRAAVT 2820
Query: 2821 IQKAFCRMVTRKLETQKCAALRIQFFLQMAVYRRRFVQQKRAAITLQHYFRTWQTRKQFL 2880
IQKAFCRMVTRKLETQKCAALRIQFFLQMAVYRRRFVQQKRAAITLQHYFRTWQTRKQFL
Sbjct: 2821 IQKAFCRMVTRKLETQKCAALRIQFFLQMAVYRRRFVQQKRAAITLQHYFRTWQTRKQFL 2880
Query: 2881 LYRKAAVVLQNHYRAFLSAKHQRQVYLQIRSSVIIIQARSKGFIQKRKFQEIKNSTIKIQ 2940
LYRKAAVVLQNHYRAFLSAKHQRQVYLQIRSSVIIIQARSKGFIQKRKFQEIKNSTIKIQ
Sbjct: 2881 LYRKAAVVLQNHYRAFLSAKHQRQVYLQIRSSVIIIQARSKGFIQKRKFQEIKNSTIKIQ 2940
Query: 2941 AMWRRYRAKKYLCKVKAACKIQAWYRCWRAHKEYLAILKAVKIIQGCFYTKLERTRFLNV 3000
AMWRRYRAKKYLCKVKAACKIQAWYRCWRAHKEYLAILKAVKIIQGCFYTKLERTRFLNV
Sbjct: 2941 AMWRRYRAKKYLCKVKAACKIQAWYRCWRAHKEYLAILKAVKIIQGCFYTKLERTRFLNV 3000
Query: 3001 RASAIIIQRKWRAILPAKIAHEHFLMIKRHRAACLIQAHYRGYKGRQVFLRQKSAALIIQ 3060
RASAIIIQRKWRAILPAKIAHEHFLMIKRHRAACLIQAHYRGYKGRQVFLRQKSAALIIQ
Sbjct: 3001 RASAIIIQRKWRAILPAKIAHEHFLMIKRHRAACLIQAHYRGYKGRQVFLRQKSAALIIQ 3060
Query: 3061 KYIRAREAGKHERIKYIEFKKSTVILQALVRGWLVRKRFLEQRAKIRLLHFTAAAYYHLN 3120
KYIRAREAGKHERIKYIEFKKSTVILQALVRGWLVRKRFLEQRAKIRLLHFTAAAYYHLN
Sbjct: 3061 KYIRAREAGKHERIKYIEFKKSTVILQALVRGWLVRKRFLEQRAKIRLLHFTAAAYYHLN 3120
Query: 3121 AVRIQRAYKLYLAVKNANKQVNSVICIQRWFRARLQEKRFIQKYHSIKKIEHEGQECLSQ 3180
AVRIQRAYKLYLAVKNANKQVNSVICIQRWFRARLQEKRFIQKYHSIKKIEHEGQECLSQ
Sbjct: 3121 AVRIQRAYKLYLAVKNANKQVNSVICIQRWFRARLQEKRFIQKYHSIKKIEHEGQECLSQ 3180
Query: 3181 RNRAASVIQKAVRHFLLRKKQEKFTSGIIKIQALWRGYSWRKKNDCTKIKAIRLSLQVVN 3240
RNRAASVIQKAVRHFLLRKKQEKFTSGIIKIQALWRGYSWRKKNDCTKIKAIRLSLQVVN
Sbjct: 3181 RNRAASVIQKAVRHFLLRKKQEKFTSGIIKIQALWRGYSWRKKNDCTKIKAIRLSLQVVN 3240
Query: 3241 REIREENKLYKRTALALHYLLTYKHLSAILEALKHLEVVTRLSPLCCENMAQSGAISKIF 3300
REIREENKLYKRTALALHYLLTYKHLSAILEALKHLEVVTRLSPLCCENMAQSGAISKIF
Sbjct: 3241 REIREENKLYKRTALALHYLLTYKHLSAILEALKHLEVVTRLSPLCCENMAQSGAISKIF 3300
Query: 3301 VLIRSCNRSIPCMEVIRYAVQVLLNVSKYEKTTSAVYDVENCIDILLELLQIYREKPGNK 3360
VLIRSCNRSIPCMEVIRYAVQVLLNVSKYEKTTSAVYDVENCIDILLELLQIYREKPGNK
Sbjct: 3301 VLIRSCNRSIPCMEVIRYAVQVLLNVSKYEKTTSAVYDVENCIDILLELLQIYREKPGNK 3360
Query: 3361 VADKGGSIFTKTCCLLAILLKTTNRASDVRSRSKVVDRIYSLYKLTAHKHKMNTERILYK 3420
VADKGGSIFTKTCCLLAILLKTTNRASDVRSRSKVVDRIYSLYKLTAHKHKMNTERILYK
Sbjct: 3361 VADKGGSIFTKTCCLLAILLKTTNRASDVRSRSKVVDRIYSLYKLTAHKHKMNTERILYK 3420
Query: 3421 QKKNSSISIPFIPETPVRTRIVSRLKPDWVLRRDNMEEITNPLQAIQMVMDTLGIPY 3477
QKKNSSISIPFIPETPVRTRIVSRLKPDWVLRRDNMEEITNPLQAIQMVMDTLGIPY
Sbjct: 3421 QKKNSSISIPFIPETPVRTRIVSRLKPDWVLRRDNMEEITNPLQAIQMVMDTLGIPY 3477
>gi|215982794 myosin VA isoform 2 [Homo sapiens]
Length = 1828
Score = 81.3 bits (199), Expect = 2e-14
Identities = 63/235 (26%), Positives = 114/235 (48%), Gaps = 37/235 (15%)
Query: 1664 SYYRAYVSKKEFLSLKNATIKLQSTVKMKQTRKQYLHLRAAALFIQQCYRSKKIAAQKRE 1723
S YR + +K+ LS + T K K+ + +Y + F R+ ++A ++
Sbjct: 708 SRYRVLMKQKDVLSDRKQTCK-NVLEKLILDKDKYQFGKTKIFF-----RAGQVAYLEKL 761
Query: 1724 EYMQMRESCIKLQAFVRGYLVRKQMRLQRKAVISLQSYFRMRKARQYYLKMYKAIIVIQN 1783
++R +CI++Q +RG+L+RK+ RKA I++Q Y R +AR Y
Sbjct: 762 RADKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCY------------- 808
Query: 1784 YYHAYKAQVNQRKNFLQVKKAATCLQAAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRVK 1843
FL+ KAAT +Q +R Y VR+ K + A + +QS RG+ R +
Sbjct: 809 ------------AKFLRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNR 856
Query: 1844 YQSVLQ--SIIKIQRWYRAYKTLHDTRTHFLKTKAAVISLQSAYRGWKVRKQIRR 1896
Y+ +L+ + IQ+ R + RTH+ ++ A+I LQ +R ++++++
Sbjct: 857 YRKILREHKAVIIQKRVRGWL----ARTHYKRSMHAIIYLQCCFRRMMAKRELKK 907
Score = 78.6 bits (192), Expect = 1e-13
Identities = 85/373 (22%), Positives = 162/373 (43%), Gaps = 42/373 (11%)
Query: 1498 FRCFQAQKLYKRRKESILTIQKYYKAYLKGKIERTNYLQKRAAAIQLQAAFRRLKAH--- 1554
FR Q L K R + + + ++G + R YL+ R AAI +Q R +A
Sbjct: 750 FRAGQVAYLEKLRADKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYA 809
Query: 1555 NLCRQIRAACVIQSYWRMRQDRVRFLNLKKTIIKFQAHVRKHQQRQKYKKM--KKAAVII 1612
R+ +AA +IQ YWRM R R+ + I Q+++R R +Y+K+ + AVII
Sbjct: 810 KFLRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVII 869
Query: 1613 QTHFRAYIFAMKVLASYQKTRSAVIVLQSAYRGMQARKMYIHILTSVIKIQSYYRAYVSK 1672
Q R ++ Y+++ A+I LQ +R M A++ + ++ Y K
Sbjct: 870 QKRVRGWL----ARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERY------K 919
Query: 1673 KEFLSLKNATIKLQSTVKMKQTRKQYLHLRAAALFIQQCYRSKKIAAQKREEYMQMRESC 1732
K + ++N ++LQ K+ + K Y L ++ Y S E ++R
Sbjct: 920 KLHIGMENKIMQLQR--KVDEQNKDYKCLVEKLTNLEGIYNS---------ETEKLRSDL 968
Query: 1733 IKLQAFVRGYLVRKQMRLQRKAVISLQSYFRMRKARQYYLKMYKAIIVIQNYYHAYKAQV 1792
+LQ L ++ ++ V+SLQ + K R+ + I+ + YK +
Sbjct: 969 ERLQ------LSEEEAKVATGRVLSLQE--EIAKLRKDLEQTRSEKKCIEEHADRYKQET 1020
Query: 1793 NQ-------RKNFLQVKKAATCLQAAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRVKYQ 1845
Q L+ +K A + + ++ + ++++ + K Q ++R++YQ
Sbjct: 1021 EQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETK-QLELDLNDERLRYQ 1079
Query: 1846 SVLQSIIKIQRWY 1858
++L +++ Y
Sbjct: 1080 NLLNEFSRLEERY 1092
Score = 70.5 bits (171), Expect = 3e-11
Identities = 63/242 (26%), Positives = 113/242 (46%), Gaps = 18/242 (7%)
Query: 2001 QKYYRAYSIGREQNHLYLKTKAAVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTK 2060
Q+++ Y + +Q + K T ++ + + K K + ++ AY K
Sbjct: 704 QEFFSRYRVLMKQKDVLSDRKQ---TCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEK 760
Query: 2061 KKYATYRASAIIIQRWYRGIKITNHQHKEYLNLKKTAIKIQSVYRGIRVRRHIQHMHR-- 2118
+ RA+ I IQ+ RG + K+YL ++K AI +Q RG + R + + + R
Sbjct: 761 LRADKLRAACIRIQKTIRGWLL----RKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTK 816
Query: 2119 AATFIKAMFKMHQSRISYHTMRKAAIVIQVRCRAYYQGKMQREKYLTILKAVK--VLQAS 2176
AAT I+ ++M+ R Y R A IV+Q +Y +G + R +Y IL+ K ++Q
Sbjct: 817 AATIIQKYWRMYVVRRRYKIRRAATIVLQ----SYLRGFLARNRYRKILREHKAVIIQKR 872
Query: 2177 FRGVRVRRTLRKMQTAATLIQSNYRRYRQQTYFNKLKKITKTVQ---QRYWAMKERNIQF 2233
RG R ++ A +Q +RR + KLK ++V+ + + M+ + +Q
Sbjct: 873 VRGWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQL 932
Query: 2234 QR 2235
QR
Sbjct: 933 QR 934
Score = 69.7 bits (169), Expect = 5e-11
Identities = 50/198 (25%), Positives = 94/198 (47%), Gaps = 21/198 (10%)
Query: 1921 KTAALVIQQNFRAWTAGRKQCMEYIELRHAVLVLQSMWKGKTLR--RQLQRQHKCAIIIQ 1978
+ A + IQ+ R W +K Y+ +R A + +Q +G R + R+ K A IIQ
Sbjct: 767 RAACIRIQKTIRGWLLRKK----YLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQ 822
Query: 1979 SYYRMHVQQKKWKIMKKAALLIQKYYRAYSIGREQNHLYLKTKAAVVTLQSAYRGMKVRK 2038
Y+RM+V ++++KI + A +++Q Y R + + R + L+ AV+ +Q RG R
Sbjct: 823 KYWRMYVVRRRYKIRRAATIVLQSYLRGF-LARNRYRKILREHKAVI-IQKRVRGWLART 880
Query: 2039 RIKDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKI------------TNHQ 2086
K A + +Q +R K++ + A ++R Y+ + I + Q
Sbjct: 881 HYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVER-YKKLHIGMENKIMQLQRKVDEQ 939
Query: 2087 HKEYLNLKKTAIKIQSVY 2104
+K+Y L + ++ +Y
Sbjct: 940 NKDYKCLVEKLTNLEGIY 957
Score = 69.3 bits (168), Expect = 6e-11
Identities = 61/274 (22%), Positives = 131/274 (47%), Gaps = 31/274 (11%)
Query: 2744 TIQAAFRGMKVRQKLKNVSEEKMAAIVNQ-SALCCYRSKTQYEAVQSEGVMIQEWYKASG 2802
T Q F +V K K+V ++ N L + K Q+ + +++A
Sbjct: 702 TYQEFFSRYRVLMKQKDVLSDRKQTCKNVLEKLILDKDKYQFGKTKI-------FFRAGQ 754
Query: 2803 LACSQEAEYHSQSRAAVTIQKAFCRMVTRK--LETQKCAALRIQFFLQ--MAVYRRRFVQ 2858
+A ++ A + IQK + RK L +K AA+ +Q +++ A +F++
Sbjct: 755 VAYLEKLRADKLRAACIRIQKTIRGWLLRKKYLRMRK-AAITMQRYVRGYQARCYAKFLR 813
Query: 2859 QKRAAITLQHYFRTWQTRKQFLLYRKAAVVLQNHYRAFLSAKHQRQVYLQIRSSVIIIQA 2918
+ +AA +Q Y+R + R+++ + R A +VLQ++ R FL+ R++ + ++ +IIQ
Sbjct: 814 RTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKA--VIIQK 871
Query: 2919 RSKGFIQKRKFQEIKNSTIKIQAMWRRYRAKKYLCKVKAACK----------------IQ 2962
R +G++ + ++ ++ I +Q +RR AK+ L K+K + +Q
Sbjct: 872 RVRGWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQ 931
Query: 2963 AWYRCWRAHKEYLAILKAVKIIQGCFYTKLERTR 2996
+ +K+Y +++ + ++G + ++ E+ R
Sbjct: 932 LQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLR 965
Score = 65.9 bits (159), Expect = 7e-10
Identities = 50/171 (29%), Positives = 86/171 (50%), Gaps = 7/171 (4%)
Query: 2285 LKKTAILIQRKYRAHLCTKHHLQFLQVQNAVIKIQSSYRRWMIRKRMREMHR--AATFIQ 2342
L+ I IQ+ R L K ++L+++ A I +Q R + R + + R AAT IQ
Sbjct: 766 LRAACIRIQKTIRGWLLRK---KYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQ 822
Query: 2343 STFRMHRLHMRYQALKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAFRGMKTRR 2402
+RM+ + RY+ +++A+ ++ Q Y A+ + + LR+ H AVI+Q RG R
Sbjct: 823 KYWRMYVVRRRYK-IRRAATIVLQSYLRGFLARNRYRKILRE-HKAVIIQKRVRGWLART 880
Query: 2403 HLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKHKLYQ 2453
H K + +Q FR ++ +R LK V+R + I ++K+ Q
Sbjct: 881 HYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQ 931
Score = 65.5 bits (158), Expect = 9e-10
Identities = 51/201 (25%), Positives = 95/201 (47%), Gaps = 9/201 (4%)
Query: 1796 KNFLQVKKAATCLQAAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRVKYQSVLQSIIKIQ 1855
K+ Q K +A Y + + A ++IQ RG+ R KY + ++ I +Q
Sbjct: 738 KDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQ 797
Query: 1856 RWYRAYKTLHDTRTHFLKTKAAVISLQSAYRGWKVRKQIRREHQAALKIQSAFRMAKAQK 1915
R+ R Y+ FL+ A +Q +R + VR++ + A + +QS R A+
Sbjct: 798 RYVRGYQA--RCYAKFLRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARN 855
Query: 1916 QFR--LFKTAALVIQQNFRAWTAGRKQCMEYIELRHAVLVLQSMWKGKTLRRQLQRQHKC 1973
++R L + A++IQ+ R W A Y HA++ LQ ++ +R+L++
Sbjct: 856 RYRKILREHKAVIIQKRVRGWLAR----THYKRSMHAIIYLQCCFRRMMAKRELKKLKIE 911
Query: 1974 AIIIQSYYRMHVQQKKWKIMK 1994
A ++ Y ++H+ + KIM+
Sbjct: 912 ARSVERYKKLHIGMEN-KIMQ 931
Score = 65.1 bits (157), Expect = 1e-09
Identities = 64/268 (23%), Positives = 115/268 (42%), Gaps = 21/268 (7%)
Query: 1547 AFRRLKAHNLCRQIR-AACVIQSYWRMRQ--DRVRFLNLKKTIIKFQAHVRKHQ------ 1597
A ++L+A + IR +A S W ++ R R L +K ++ + K+
Sbjct: 677 AVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQKDVLSDRKQTCKNVLEKLIL 736
Query: 1598 QRQKYKKMKKAAVIIQTHFRAYIFAMKVLASYQKTRSAVIVLQSAYRGMQARKMYIHILT 1657
+ KY+ K + + AY+ ++ K R+A I +Q RG RK Y+ +
Sbjct: 737 DKDKYQ-FGKTKIFFRAGQVAYLEKLRA----DKLRAACIRIQKTIRGWLLRKKYLRMRK 791
Query: 1658 SVIKIQSYYRAYVSK--KEFLSLKNATIKLQSTVKMKQTRKQYLHLRAAALFIQQCYRSK 1715
+ I +Q Y R Y ++ +FL A +Q +M R++Y RAA + +Q R
Sbjct: 792 AAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRG- 850
Query: 1716 KIAAQKREEYMQMRESCIKLQAFVRGYLVRKQMRLQRKAVISLQSYFRMRKARQYYLKMY 1775
A+ R + + +Q VRG+L R + A+I LQ FR A++ K+
Sbjct: 851 -FLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLK 909
Query: 1776 KAIIVIQNYYHAYKAQVNQRKNFLQVKK 1803
++ Y K + +Q+++
Sbjct: 910 IEARSVERY---KKLHIGMENKIMQLQR 934
Score = 64.3 bits (155), Expect = 2e-09
Identities = 63/240 (26%), Positives = 117/240 (48%), Gaps = 17/240 (7%)
Query: 1816 KVRQLIKQQSIAALKIQSAFRGYNKRVKYQSVLQSIIKIQRWYRAYKTLHDTRTHFLKTK 1875
+ R L+KQ+ + + + Q+ K + + Q K + ++RA + + + K +
Sbjct: 709 RYRVLMKQKDVLSDRKQTCKNVLEKLILDKDKYQ-FGKTKIFFRAGQVAYLEKLRADKLR 767
Query: 1876 AAVISLQSAYRGWKVRKQIRREHQAALKIQSAFR--MAKAQKQFRLFKTAALVIQQNFRA 1933
AA I +Q RGW +RK+ R +AA+ +Q R A+ +F AA +IQ+ +R
Sbjct: 768 AACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRM 827
Query: 1934 WTAGRKQCMEYIELRHAVLVLQSMWKGKTLR---RQLQRQHKCAIIIQSYYRMHVQQKKW 1990
+ R+ Y R A +VLQS +G R R++ R+HK A+IIQ R + + +
Sbjct: 828 YVVRRR----YKIRRAATIVLQSYLRGFLARNRYRKILREHK-AVIIQKRVRGWLARTHY 882
Query: 1991 KIMKKAALLIQKYYRAYSIGREQNHLYLKTKAAVVTLQSAYRG-----MKVRKRIKDCNK 2045
K A + +Q +R RE L ++ + +V + + G M++++++ + NK
Sbjct: 883 KRSMHAIIYLQCCFRRMMAKRELKKLKIEAR-SVERYKKLHIGMENKIMQLQRKVDEQNK 941
Score = 62.8 bits (151), Expect = 6e-09
Identities = 72/333 (21%), Positives = 143/333 (42%), Gaps = 54/333 (16%)
Query: 1287 KRHQEREKAARI-IQLAVINFLAKQRLRKRVNAALVIQKYWRRVLAQRKLLMLKKEKLEK 1345
K ++ +AA I IQ + +L +++ + AA+ +Q+Y R A+ L++
Sbjct: 760 KLRADKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRR----- 814
Query: 1346 VQNKAASLIQGYWRRYSTRQRFLKLKYYSIILQSRIRMIIAVTSYKRYL--WATVTIQRH 1403
KAA++IQ YWR Y R+R+ + +I+LQS +R +A Y++ L V IQ+
Sbjct: 815 --TKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKR 872
Query: 1404 WRAYLRRKQDQQRYEMLKSSTLIIQSMFRKWKQRKMQSQVKATVILQRAFREWHLRKQAK 1463
R +L R Y+ + + +Q FR+ ++ ++K +++ H+ + K
Sbjct: 873 VRGWLAR----THYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENK 928
Query: 1464 EENSAIIIQSWYRMHKELRKYIYIRSCVVIIQKRFRCFQAQKLYKRRKESILTIQKYYKA 1523
I+Q + + + K YK E + ++ Y +
Sbjct: 929 -----------------------------IMQLQRKVDEQNKDYKCLVEKLTNLEGIYNS 959
Query: 1524 ---YLKGKIERTNYLQKRA-----AAIQLQAAFRRLKAHNLCRQIRAACVIQSYWRMRQD 1575
L+ +ER ++ A + LQ +L+ + C+ + R +Q+
Sbjct: 960 ETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQE 1019
Query: 1576 RVRFL-NLKK--TIIKFQAHVRKHQQRQKYKKM 1605
+ + NLK+ T++K + H+ Q+ K+M
Sbjct: 1020 TEQLVSNLKEENTLLKQEKEALNHRIVQQAKEM 1052
Score = 60.1 bits (144), Expect = 4e-08
Identities = 51/194 (26%), Positives = 90/194 (46%), Gaps = 25/194 (12%)
Query: 2202 RYRQQTYFNKLK---------KITKTVQQRYWAMKERNIQFQRYNKLRHSVIYIQAIFRG 2252
R Q Y KL+ +I KT+ R W ++++ Y ++R + I +Q RG
Sbjct: 751 RAGQVAYLEKLRADKLRAACIRIQKTI--RGWLLRKK------YLRMRKAAITMQRYVRG 802
Query: 2253 KKARRHLKMMHI--AATLIQRRFRTLMMRRRFLSLKKTAILIQRKYRAHLCTKHHLQFLQ 2310
+AR + K + AAT+IQ+ +R ++RRR+ + I++Q R L + + L+
Sbjct: 803 YQARCYAKFLRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILR 862
Query: 2311 VQNAVIKIQSSYRRWMIRKRMREMHRAATFIQSTFRMHRLHMRYQALKQASVVIQQQYQ- 2369
AVI IQ R W+ R + A ++Q FR + LK + +++ +
Sbjct: 863 EHKAVI-IQKRVRGWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKL 921
Query: 2370 ----ANRAAKLQRQ 2379
N+ +LQR+
Sbjct: 922 HIGMENKIMQLQRK 935
Score = 59.3 bits (142), Expect = 6e-08
Identities = 50/195 (25%), Positives = 98/195 (50%), Gaps = 26/195 (13%)
Query: 2407 MHSSATLIQSRFRSLLVRRRFISLKKATIFVQRK---YRATICAKHKLYQFLHLRKAAIT 2463
+ ++ IQ R L+R++++ ++KA I +QR Y+A AK FL KAA
Sbjct: 766 LRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAK-----FLRRTKAATI 820
Query: 2464 IQSSYRRLMVKKKLQEMQRAAVLIQATFRMYRTYITFQ--TWKHASILIQQHYRTYRAAK 2521
IQ +R +V+++ + + A +++Q+ R + ++ +H +++IQ+ R +
Sbjct: 821 IQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGW---- 876
Query: 2522 LQRENYIRQWHSAVVIQAAYKGMKARQLLREKHKASIVIQSTYRMYRQYCFYQKLQ--WA 2579
L R +Y R H+ + +Q ++ M A+ RE K I +S R Y+KL
Sbjct: 877 LARTHYKRSMHAIIYLQCCFRRMMAK---RELKKLKIEARSVER-------YKKLHIGME 926
Query: 2580 TKIIQEKYRANKKKQ 2594
KI+Q + + +++ +
Sbjct: 927 NKIMQLQRKVDEQNK 941
Score = 59.3 bits (142), Expect = 6e-08
Identities = 48/165 (29%), Positives = 79/165 (47%), Gaps = 14/165 (8%)
Query: 2133 RISYHTMRKAAIVIQVRCRAYYQGKMQREKYLTILKAVKVLQASFRGVRVRRTLRKMQTA 2192
R Y MRKAAI +Q R Y Q + K+L KA ++Q +R VRR + + A
Sbjct: 783 RKKYLRMRKAAITMQRYVRGY-QARCYA-KFLRRTKAATIIQKYWRMYVVRRRYKIRRAA 840
Query: 2193 ATLIQSNYRRYRQQTYFNKLKKITKTV--QQRYWAMKERNIQFQRYNKLRHSVIYIQAIF 2250
++QS R + + + K+ + K V Q+R R Y + H++IY+Q F
Sbjct: 841 TIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLART----HYKRSMHAIIYLQCCF 896
Query: 2251 RGKKARRHLKMMHIAATLIQRRFRTLMMRRRFLSLKKTAILIQRK 2295
R A+R LK + I A ++R ++ + ++ + +QRK
Sbjct: 897 RRMMAKRELKKLKIEARSVER------YKKLHIGMENKIMQLQRK 935
Score = 58.5 bits (140), Expect = 1e-07
Identities = 59/224 (26%), Positives = 101/224 (45%), Gaps = 41/224 (18%)
Query: 2581 KIIQEKYRANKKKQKVFQHNELKKETCVQAGFQDMNIKKQIQEQHQAAIIIQKHCKAFKI 2640
K+I +K + K K+F +AG K + + A I IQK + + +
Sbjct: 733 KLILDKDKYQFGKTKIF----------FRAGQVAYLEKLRADKLRAACIRIQKTIRGWLL 782
Query: 2641 RKHYLHLRATVVSIQRRYRKLTAVRTQAVICIQSYYRGFKVRKDIQNMHR--AATLIQSF 2698
RK YL +R +++QR Y RG++ R + + R AAT+IQ +
Sbjct: 783 RKKYLRMRKAAITMQR------------------YVRGYQARCYAKFLRRTKAATIIQKY 824
Query: 2699 YRMHRAKVDYETKKTAIVVIQNYYRLYVRVKTERKNFLAVQKSVRTIQAAFRGMKVRQKL 2758
+RM+ + Y+ ++ A +V+Q+Y R ++ RK L K+V IQ RG R
Sbjct: 825 WRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRK-ILREHKAV-IIQKRVRGWLARTHY 882
Query: 2759 KNVSEEKMAAIVNQSALCCYR---SKTQYEAVQSEGVMIQEWYK 2799
K M AI+ CC+R +K + + ++ E ++ + K
Sbjct: 883 K----RSMHAIIYLQ--CCFRRMMAKRELKKLKIEARSVERYKK 920
Score = 57.8 bits (138), Expect = 2e-07
Identities = 47/157 (29%), Positives = 85/157 (54%), Gaps = 14/157 (8%)
Query: 3018 KIAHEHFLMIKRHRAACL-IQAHYRGYKGRQVFLRQKSAALIIQKYIRAREAGKHERIKY 3076
++A+ L + RAAC+ IQ RG+ R+ +LR + AA+ +Q+Y+R +A + K+
Sbjct: 754 QVAYLEKLRADKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCY--AKF 811
Query: 3077 IEFKKSTVILQALVRGWLVRKRFLEQRAKIRLLH-----FTAAAYYHL-----NAVRIQR 3126
+ K+ I+Q R ++VR+R+ +RA +L F A Y AV IQ+
Sbjct: 812 LRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQK 871
Query: 3127 AYKLYLAVKNANKQVNSVICIQRWFRARLQEKRFIQK 3163
+ +LA + + ++++I +Q FR R+ KR ++K
Sbjct: 872 RVRGWLARTHYKRSMHAIIYLQCCFR-RMMAKRELKK 907
Score = 55.5 bits (132), Expect = 9e-07
Identities = 77/355 (21%), Positives = 158/355 (44%), Gaps = 41/355 (11%)
Query: 2457 LRKAAITIQSSYRRLMVKKKLQEMQRAAVLIQATFRMY--RTYITFQTWKHASILIQQHY 2514
LR A I IQ + R +++KK M++AA+ +Q R Y R Y F A+ +IQ+++
Sbjct: 766 LRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYW 825
Query: 2515 RTYRAAKLQRENYIRQWHSAVVIQAAYKGMKARQLLRE---KHKASIVIQSTYRMYRQYC 2571
R Y + R Y + + +V+Q+ +G AR R+ +HKA ++IQ R +
Sbjct: 826 RMY----VVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKA-VIIQKRVRGWLART 880
Query: 2572 FYQKLQWATKIIQEKYRANKKKQKV----FQHNELKKETCVQAGFQD--MNIKKQIQEQH 2625
Y++ A +Q +R K+++ + +++ + G ++ M +++++ EQ+
Sbjct: 881 HYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQN 940
Query: 2626 Q-AAIIIQKHCKAFKI-RKHYLHLRATVVSIQRRYRKLTAVRTQAVICIQSYYRGFKVRK 2683
+ +++K I LR+ + +Q + V T V+ +Q K+RK
Sbjct: 941 KDYKCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEE-AKVATGRVLSLQEEIA--KLRK 997
Query: 2684 DIQNMHRAATLIQSFYRMHRAKVDYETKKTAIVVIQNYYRLYVRVKTERKNFLAVQKSVR 2743
D++ I+ H + ET++ ++ N +K E++ + R
Sbjct: 998 DLEQTRSEKKCIEE----HADRYKQETEQ----LVSNLKEENTLLKQEKEAL-----NHR 1044
Query: 2744 TIQAAFRGMKVRQKLKNVSEEKMAAIVNQSALCCYRSKTQYEAVQSEGVMIQEWY 2798
+Q A +++ E+K+ Q L + +Y+ + +E ++E Y
Sbjct: 1045 IVQQA-------KEMTETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEERY 1092
Score = 50.8 bits (120), Expect = 2e-05
Identities = 49/212 (23%), Positives = 93/212 (43%), Gaps = 38/212 (17%)
Query: 3062 YIRAREAGKHERIKYIEFKKSTVILQALVRGWLVRKRFLEQR-AKIRLLHFT----AAAY 3116
+ RA + E+++ + + + + +Q +RGWL+RK++L R A I + + A Y
Sbjct: 749 FFRAGQVAYLEKLRADKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCY 808
Query: 3117 YHL-----NAVRIQRAYKLYLAVKNANKQVNSVICIQRWFRARLQEKRFIQKYHSIKKIE 3171
A IQ+ +++Y+ + + + I +Q + R L R+ +KI
Sbjct: 809 AKFLRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRY-------RKI- 860
Query: 3172 HEGQECLSQRNRAASVIQKAVRHFLLRKKQEKFTSGIIKIQALWRGYSWRKKNDCTKIKA 3231
R A +IQK VR +L R ++ II +Q +R +++ KI+A
Sbjct: 861 --------LREHKAVIIQKRVRGWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIEA 912
Query: 3232 ------------IRLSLQVVNREIREENKLYK 3251
+ + + R++ E+NK YK
Sbjct: 913 RSVERYKKLHIGMENKIMQLQRKVDEQNKDYK 944
Score = 50.4 bits (119), Expect = 3e-05
Identities = 42/178 (23%), Positives = 85/178 (47%), Gaps = 12/178 (6%)
Query: 2908 QIRSSVIIIQARSKGFIQKRKFQEIKNSTIKIQAMWRRYRAK---KYLCKVKAACKIQAW 2964
++R++ I IQ +G++ ++K+ ++ + I +Q R Y+A+ K+L + KAA IQ +
Sbjct: 765 KLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKY 824
Query: 2965 YRCWRAHKEYLAILKAVKIIQGCFYTKLERTRFLNV--RASAIIIQRKWRAILPAKIAHE 3022
+R + + Y A ++Q L R R+ + A+IIQ++ R L A
Sbjct: 825 WRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWL----ART 880
Query: 3023 HFLMIKRHRAACLIQAHYRGYKGRQVFLRQKSAALIIQKYIRAREAGKHERIKYIEFK 3080
H+ + A +Q +R ++ + K A +++Y + G +I ++ K
Sbjct: 881 HYK--RSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERY-KKLHIGMENKIMQLQRK 935
Score = 37.7 bits (86), Expect = 0.20
Identities = 30/102 (29%), Positives = 50/102 (49%), Gaps = 28/102 (27%)
Query: 1265 KEIRAARLIQTTWRKYKLKTDLKRHQEREKAARIIQLAVINFLAKQRLRK--RVNAALVI 1322
+ +AA +IQ WR Y ++ +R++ R A ++Q + FLA+ R RK R + A++I
Sbjct: 813 RRTKAATIIQKYWRMYVVR---RRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVII 869
Query: 1323 QKY-----------------------WRRVLAQRKLLMLKKE 1341
QK +RR++A+R+L LK E
Sbjct: 870 QKRVRGWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIE 911
>gi|215982791 myosin VA isoform 1 [Homo sapiens]
Length = 1855
Score = 81.3 bits (199), Expect = 2e-14
Identities = 63/235 (26%), Positives = 114/235 (48%), Gaps = 37/235 (15%)
Query: 1664 SYYRAYVSKKEFLSLKNATIKLQSTVKMKQTRKQYLHLRAAALFIQQCYRSKKIAAQKRE 1723
S YR + +K+ LS + T K K+ + +Y + F R+ ++A ++
Sbjct: 708 SRYRVLMKQKDVLSDRKQTCK-NVLEKLILDKDKYQFGKTKIFF-----RAGQVAYLEKL 761
Query: 1724 EYMQMRESCIKLQAFVRGYLVRKQMRLQRKAVISLQSYFRMRKARQYYLKMYKAIIVIQN 1783
++R +CI++Q +RG+L+RK+ RKA I++Q Y R +AR Y
Sbjct: 762 RADKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCY------------- 808
Query: 1784 YYHAYKAQVNQRKNFLQVKKAATCLQAAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRVK 1843
FL+ KAAT +Q +R Y VR+ K + A + +QS RG+ R +
Sbjct: 809 ------------AKFLRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNR 856
Query: 1844 YQSVLQ--SIIKIQRWYRAYKTLHDTRTHFLKTKAAVISLQSAYRGWKVRKQIRR 1896
Y+ +L+ + IQ+ R + RTH+ ++ A+I LQ +R ++++++
Sbjct: 857 YRKILREHKAVIIQKRVRGWL----ARTHYKRSMHAIIYLQCCFRRMMAKRELKK 907
Score = 78.6 bits (192), Expect = 1e-13
Identities = 85/373 (22%), Positives = 162/373 (43%), Gaps = 42/373 (11%)
Query: 1498 FRCFQAQKLYKRRKESILTIQKYYKAYLKGKIERTNYLQKRAAAIQLQAAFRRLKAH--- 1554
FR Q L K R + + + ++G + R YL+ R AAI +Q R +A
Sbjct: 750 FRAGQVAYLEKLRADKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYA 809
Query: 1555 NLCRQIRAACVIQSYWRMRQDRVRFLNLKKTIIKFQAHVRKHQQRQKYKKM--KKAAVII 1612
R+ +AA +IQ YWRM R R+ + I Q+++R R +Y+K+ + AVII
Sbjct: 810 KFLRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVII 869
Query: 1613 QTHFRAYIFAMKVLASYQKTRSAVIVLQSAYRGMQARKMYIHILTSVIKIQSYYRAYVSK 1672
Q R ++ Y+++ A+I LQ +R M A++ + ++ Y K
Sbjct: 870 QKRVRGWL----ARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERY------K 919
Query: 1673 KEFLSLKNATIKLQSTVKMKQTRKQYLHLRAAALFIQQCYRSKKIAAQKREEYMQMRESC 1732
K + ++N ++LQ K+ + K Y L ++ Y S E ++R
Sbjct: 920 KLHIGMENKIMQLQR--KVDEQNKDYKCLVEKLTNLEGIYNS---------ETEKLRSDL 968
Query: 1733 IKLQAFVRGYLVRKQMRLQRKAVISLQSYFRMRKARQYYLKMYKAIIVIQNYYHAYKAQV 1792
+LQ L ++ ++ V+SLQ + K R+ + I+ + YK +
Sbjct: 969 ERLQ------LSEEEAKVATGRVLSLQE--EIAKLRKDLEQTRSEKKCIEEHADRYKQET 1020
Query: 1793 NQ-------RKNFLQVKKAATCLQAAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRVKYQ 1845
Q L+ +K A + + ++ + ++++ + K Q ++R++YQ
Sbjct: 1021 EQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETK-QLELDLNDERLRYQ 1079
Query: 1846 SVLQSIIKIQRWY 1858
++L +++ Y
Sbjct: 1080 NLLNEFSRLEERY 1092
Score = 70.5 bits (171), Expect = 3e-11
Identities = 63/242 (26%), Positives = 113/242 (46%), Gaps = 18/242 (7%)
Query: 2001 QKYYRAYSIGREQNHLYLKTKAAVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTK 2060
Q+++ Y + +Q + K T ++ + + K K + ++ AY K
Sbjct: 704 QEFFSRYRVLMKQKDVLSDRKQ---TCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEK 760
Query: 2061 KKYATYRASAIIIQRWYRGIKITNHQHKEYLNLKKTAIKIQSVYRGIRVRRHIQHMHR-- 2118
+ RA+ I IQ+ RG + K+YL ++K AI +Q RG + R + + + R
Sbjct: 761 LRADKLRAACIRIQKTIRGWLL----RKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTK 816
Query: 2119 AATFIKAMFKMHQSRISYHTMRKAAIVIQVRCRAYYQGKMQREKYLTILKAVK--VLQAS 2176
AAT I+ ++M+ R Y R A IV+Q +Y +G + R +Y IL+ K ++Q
Sbjct: 817 AATIIQKYWRMYVVRRRYKIRRAATIVLQ----SYLRGFLARNRYRKILREHKAVIIQKR 872
Query: 2177 FRGVRVRRTLRKMQTAATLIQSNYRRYRQQTYFNKLKKITKTVQ---QRYWAMKERNIQF 2233
RG R ++ A +Q +RR + KLK ++V+ + + M+ + +Q
Sbjct: 873 VRGWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQL 932
Query: 2234 QR 2235
QR
Sbjct: 933 QR 934
Score = 69.7 bits (169), Expect = 5e-11
Identities = 50/198 (25%), Positives = 94/198 (47%), Gaps = 21/198 (10%)
Query: 1921 KTAALVIQQNFRAWTAGRKQCMEYIELRHAVLVLQSMWKGKTLR--RQLQRQHKCAIIIQ 1978
+ A + IQ+ R W +K Y+ +R A + +Q +G R + R+ K A IIQ
Sbjct: 767 RAACIRIQKTIRGWLLRKK----YLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQ 822
Query: 1979 SYYRMHVQQKKWKIMKKAALLIQKYYRAYSIGREQNHLYLKTKAAVVTLQSAYRGMKVRK 2038
Y+RM+V ++++KI + A +++Q Y R + + R + L+ AV+ +Q RG R
Sbjct: 823 KYWRMYVVRRRYKIRRAATIVLQSYLRGF-LARNRYRKILREHKAVI-IQKRVRGWLART 880
Query: 2039 RIKDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKI------------TNHQ 2086
K A + +Q +R K++ + A ++R Y+ + I + Q
Sbjct: 881 HYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVER-YKKLHIGMENKIMQLQRKVDEQ 939
Query: 2087 HKEYLNLKKTAIKIQSVY 2104
+K+Y L + ++ +Y
Sbjct: 940 NKDYKCLVEKLTNLEGIY 957
Score = 69.3 bits (168), Expect = 6e-11
Identities = 61/274 (22%), Positives = 131/274 (47%), Gaps = 31/274 (11%)
Query: 2744 TIQAAFRGMKVRQKLKNVSEEKMAAIVNQ-SALCCYRSKTQYEAVQSEGVMIQEWYKASG 2802
T Q F +V K K+V ++ N L + K Q+ + +++A
Sbjct: 702 TYQEFFSRYRVLMKQKDVLSDRKQTCKNVLEKLILDKDKYQFGKTKI-------FFRAGQ 754
Query: 2803 LACSQEAEYHSQSRAAVTIQKAFCRMVTRK--LETQKCAALRIQFFLQ--MAVYRRRFVQ 2858
+A ++ A + IQK + RK L +K AA+ +Q +++ A +F++
Sbjct: 755 VAYLEKLRADKLRAACIRIQKTIRGWLLRKKYLRMRK-AAITMQRYVRGYQARCYAKFLR 813
Query: 2859 QKRAAITLQHYFRTWQTRKQFLLYRKAAVVLQNHYRAFLSAKHQRQVYLQIRSSVIIIQA 2918
+ +AA +Q Y+R + R+++ + R A +VLQ++ R FL+ R++ + ++ +IIQ
Sbjct: 814 RTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKA--VIIQK 871
Query: 2919 RSKGFIQKRKFQEIKNSTIKIQAMWRRYRAKKYLCKVKAACK----------------IQ 2962
R +G++ + ++ ++ I +Q +RR AK+ L K+K + +Q
Sbjct: 872 RVRGWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQ 931
Query: 2963 AWYRCWRAHKEYLAILKAVKIIQGCFYTKLERTR 2996
+ +K+Y +++ + ++G + ++ E+ R
Sbjct: 932 LQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLR 965
Score = 65.9 bits (159), Expect = 7e-10
Identities = 50/171 (29%), Positives = 86/171 (50%), Gaps = 7/171 (4%)
Query: 2285 LKKTAILIQRKYRAHLCTKHHLQFLQVQNAVIKIQSSYRRWMIRKRMREMHR--AATFIQ 2342
L+ I IQ+ R L K ++L+++ A I +Q R + R + + R AAT IQ
Sbjct: 766 LRAACIRIQKTIRGWLLRK---KYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQ 822
Query: 2343 STFRMHRLHMRYQALKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAFRGMKTRR 2402
+RM+ + RY+ +++A+ ++ Q Y A+ + + LR+ H AVI+Q RG R
Sbjct: 823 KYWRMYVVRRRYK-IRRAATIVLQSYLRGFLARNRYRKILRE-HKAVIIQKRVRGWLART 880
Query: 2403 HLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKHKLYQ 2453
H K + +Q FR ++ +R LK V+R + I ++K+ Q
Sbjct: 881 HYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQ 931
Score = 65.5 bits (158), Expect = 9e-10
Identities = 51/201 (25%), Positives = 95/201 (47%), Gaps = 9/201 (4%)
Query: 1796 KNFLQVKKAATCLQAAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRVKYQSVLQSIIKIQ 1855
K+ Q K +A Y + + A ++IQ RG+ R KY + ++ I +Q
Sbjct: 738 KDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQ 797
Query: 1856 RWYRAYKTLHDTRTHFLKTKAAVISLQSAYRGWKVRKQIRREHQAALKIQSAFRMAKAQK 1915
R+ R Y+ FL+ A +Q +R + VR++ + A + +QS R A+
Sbjct: 798 RYVRGYQA--RCYAKFLRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARN 855
Query: 1916 QFR--LFKTAALVIQQNFRAWTAGRKQCMEYIELRHAVLVLQSMWKGKTLRRQLQRQHKC 1973
++R L + A++IQ+ R W A Y HA++ LQ ++ +R+L++
Sbjct: 856 RYRKILREHKAVIIQKRVRGWLAR----THYKRSMHAIIYLQCCFRRMMAKRELKKLKIE 911
Query: 1974 AIIIQSYYRMHVQQKKWKIMK 1994
A ++ Y ++H+ + KIM+
Sbjct: 912 ARSVERYKKLHIGMEN-KIMQ 931
Score = 65.1 bits (157), Expect = 1e-09
Identities = 64/268 (23%), Positives = 115/268 (42%), Gaps = 21/268 (7%)
Query: 1547 AFRRLKAHNLCRQIR-AACVIQSYWRMRQ--DRVRFLNLKKTIIKFQAHVRKHQ------ 1597
A ++L+A + IR +A S W ++ R R L +K ++ + K+
Sbjct: 677 AVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQKDVLSDRKQTCKNVLEKLIL 736
Query: 1598 QRQKYKKMKKAAVIIQTHFRAYIFAMKVLASYQKTRSAVIVLQSAYRGMQARKMYIHILT 1657
+ KY+ K + + AY+ ++ K R+A I +Q RG RK Y+ +
Sbjct: 737 DKDKYQ-FGKTKIFFRAGQVAYLEKLRA----DKLRAACIRIQKTIRGWLLRKKYLRMRK 791
Query: 1658 SVIKIQSYYRAYVSK--KEFLSLKNATIKLQSTVKMKQTRKQYLHLRAAALFIQQCYRSK 1715
+ I +Q Y R Y ++ +FL A +Q +M R++Y RAA + +Q R
Sbjct: 792 AAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRG- 850
Query: 1716 KIAAQKREEYMQMRESCIKLQAFVRGYLVRKQMRLQRKAVISLQSYFRMRKARQYYLKMY 1775
A+ R + + +Q VRG+L R + A+I LQ FR A++ K+
Sbjct: 851 -FLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLK 909
Query: 1776 KAIIVIQNYYHAYKAQVNQRKNFLQVKK 1803
++ Y K + +Q+++
Sbjct: 910 IEARSVERY---KKLHIGMENKIMQLQR 934
Score = 64.3 bits (155), Expect = 2e-09
Identities = 63/240 (26%), Positives = 117/240 (48%), Gaps = 17/240 (7%)
Query: 1816 KVRQLIKQQSIAALKIQSAFRGYNKRVKYQSVLQSIIKIQRWYRAYKTLHDTRTHFLKTK 1875
+ R L+KQ+ + + + Q+ K + + Q K + ++RA + + + K +
Sbjct: 709 RYRVLMKQKDVLSDRKQTCKNVLEKLILDKDKYQ-FGKTKIFFRAGQVAYLEKLRADKLR 767
Query: 1876 AAVISLQSAYRGWKVRKQIRREHQAALKIQSAFR--MAKAQKQFRLFKTAALVIQQNFRA 1933
AA I +Q RGW +RK+ R +AA+ +Q R A+ +F AA +IQ+ +R
Sbjct: 768 AACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRM 827
Query: 1934 WTAGRKQCMEYIELRHAVLVLQSMWKGKTLR---RQLQRQHKCAIIIQSYYRMHVQQKKW 1990
+ R+ Y R A +VLQS +G R R++ R+HK A+IIQ R + + +
Sbjct: 828 YVVRRR----YKIRRAATIVLQSYLRGFLARNRYRKILREHK-AVIIQKRVRGWLARTHY 882
Query: 1991 KIMKKAALLIQKYYRAYSIGREQNHLYLKTKAAVVTLQSAYRG-----MKVRKRIKDCNK 2045
K A + +Q +R RE L ++ + +V + + G M++++++ + NK
Sbjct: 883 KRSMHAIIYLQCCFRRMMAKRELKKLKIEAR-SVERYKKLHIGMENKIMQLQRKVDEQNK 941
Score = 62.8 bits (151), Expect = 6e-09
Identities = 72/333 (21%), Positives = 143/333 (42%), Gaps = 54/333 (16%)
Query: 1287 KRHQEREKAARI-IQLAVINFLAKQRLRKRVNAALVIQKYWRRVLAQRKLLMLKKEKLEK 1345
K ++ +AA I IQ + +L +++ + AA+ +Q+Y R A+ L++
Sbjct: 760 KLRADKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRR----- 814
Query: 1346 VQNKAASLIQGYWRRYSTRQRFLKLKYYSIILQSRIRMIIAVTSYKRYL--WATVTIQRH 1403
KAA++IQ YWR Y R+R+ + +I+LQS +R +A Y++ L V IQ+
Sbjct: 815 --TKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKR 872
Query: 1404 WRAYLRRKQDQQRYEMLKSSTLIIQSMFRKWKQRKMQSQVKATVILQRAFREWHLRKQAK 1463
R +L R Y+ + + +Q FR+ ++ ++K +++ H+ + K
Sbjct: 873 VRGWLAR----THYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENK 928
Query: 1464 EENSAIIIQSWYRMHKELRKYIYIRSCVVIIQKRFRCFQAQKLYKRRKESILTIQKYYKA 1523
I+Q + + + K YK E + ++ Y +
Sbjct: 929 -----------------------------IMQLQRKVDEQNKDYKCLVEKLTNLEGIYNS 959
Query: 1524 ---YLKGKIERTNYLQKRA-----AAIQLQAAFRRLKAHNLCRQIRAACVIQSYWRMRQD 1575
L+ +ER ++ A + LQ +L+ + C+ + R +Q+
Sbjct: 960 ETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQE 1019
Query: 1576 RVRFL-NLKK--TIIKFQAHVRKHQQRQKYKKM 1605
+ + NLK+ T++K + H+ Q+ K+M
Sbjct: 1020 TEQLVSNLKEENTLLKQEKEALNHRIVQQAKEM 1052
Score = 60.1 bits (144), Expect = 4e-08
Identities = 51/194 (26%), Positives = 90/194 (46%), Gaps = 25/194 (12%)
Query: 2202 RYRQQTYFNKLK---------KITKTVQQRYWAMKERNIQFQRYNKLRHSVIYIQAIFRG 2252
R Q Y KL+ +I KT+ R W ++++ Y ++R + I +Q RG
Sbjct: 751 RAGQVAYLEKLRADKLRAACIRIQKTI--RGWLLRKK------YLRMRKAAITMQRYVRG 802
Query: 2253 KKARRHLKMMHI--AATLIQRRFRTLMMRRRFLSLKKTAILIQRKYRAHLCTKHHLQFLQ 2310
+AR + K + AAT+IQ+ +R ++RRR+ + I++Q R L + + L+
Sbjct: 803 YQARCYAKFLRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILR 862
Query: 2311 VQNAVIKIQSSYRRWMIRKRMREMHRAATFIQSTFRMHRLHMRYQALKQASVVIQQQYQ- 2369
AVI IQ R W+ R + A ++Q FR + LK + +++ +
Sbjct: 863 EHKAVI-IQKRVRGWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKL 921
Query: 2370 ----ANRAAKLQRQ 2379
N+ +LQR+
Sbjct: 922 HIGMENKIMQLQRK 935
Score = 59.3 bits (142), Expect = 6e-08
Identities = 50/195 (25%), Positives = 98/195 (50%), Gaps = 26/195 (13%)
Query: 2407 MHSSATLIQSRFRSLLVRRRFISLKKATIFVQRK---YRATICAKHKLYQFLHLRKAAIT 2463
+ ++ IQ R L+R++++ ++KA I +QR Y+A AK FL KAA
Sbjct: 766 LRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAK-----FLRRTKAATI 820
Query: 2464 IQSSYRRLMVKKKLQEMQRAAVLIQATFRMYRTYITFQ--TWKHASILIQQHYRTYRAAK 2521
IQ +R +V+++ + + A +++Q+ R + ++ +H +++IQ+ R +
Sbjct: 821 IQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGW---- 876
Query: 2522 LQRENYIRQWHSAVVIQAAYKGMKARQLLREKHKASIVIQSTYRMYRQYCFYQKLQ--WA 2579
L R +Y R H+ + +Q ++ M A+ RE K I +S R Y+KL
Sbjct: 877 LARTHYKRSMHAIIYLQCCFRRMMAK---RELKKLKIEARSVER-------YKKLHIGME 926
Query: 2580 TKIIQEKYRANKKKQ 2594
KI+Q + + +++ +
Sbjct: 927 NKIMQLQRKVDEQNK 941
Score = 59.3 bits (142), Expect = 6e-08
Identities = 48/165 (29%), Positives = 79/165 (47%), Gaps = 14/165 (8%)
Query: 2133 RISYHTMRKAAIVIQVRCRAYYQGKMQREKYLTILKAVKVLQASFRGVRVRRTLRKMQTA 2192
R Y MRKAAI +Q R Y Q + K+L KA ++Q +R VRR + + A
Sbjct: 783 RKKYLRMRKAAITMQRYVRGY-QARCYA-KFLRRTKAATIIQKYWRMYVVRRRYKIRRAA 840
Query: 2193 ATLIQSNYRRYRQQTYFNKLKKITKTV--QQRYWAMKERNIQFQRYNKLRHSVIYIQAIF 2250
++QS R + + + K+ + K V Q+R R Y + H++IY+Q F
Sbjct: 841 TIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLART----HYKRSMHAIIYLQCCF 896
Query: 2251 RGKKARRHLKMMHIAATLIQRRFRTLMMRRRFLSLKKTAILIQRK 2295
R A+R LK + I A ++R ++ + ++ + +QRK
Sbjct: 897 RRMMAKRELKKLKIEARSVER------YKKLHIGMENKIMQLQRK 935
Score = 58.5 bits (140), Expect = 1e-07
Identities = 59/224 (26%), Positives = 101/224 (45%), Gaps = 41/224 (18%)
Query: 2581 KIIQEKYRANKKKQKVFQHNELKKETCVQAGFQDMNIKKQIQEQHQAAIIIQKHCKAFKI 2640
K+I +K + K K+F +AG K + + A I IQK + + +
Sbjct: 733 KLILDKDKYQFGKTKIF----------FRAGQVAYLEKLRADKLRAACIRIQKTIRGWLL 782
Query: 2641 RKHYLHLRATVVSIQRRYRKLTAVRTQAVICIQSYYRGFKVRKDIQNMHR--AATLIQSF 2698
RK YL +R +++QR Y RG++ R + + R AAT+IQ +
Sbjct: 783 RKKYLRMRKAAITMQR------------------YVRGYQARCYAKFLRRTKAATIIQKY 824
Query: 2699 YRMHRAKVDYETKKTAIVVIQNYYRLYVRVKTERKNFLAVQKSVRTIQAAFRGMKVRQKL 2758
+RM+ + Y+ ++ A +V+Q+Y R ++ RK L K+V IQ RG R
Sbjct: 825 WRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRK-ILREHKAV-IIQKRVRGWLARTHY 882
Query: 2759 KNVSEEKMAAIVNQSALCCYR---SKTQYEAVQSEGVMIQEWYK 2799
K M AI+ CC+R +K + + ++ E ++ + K
Sbjct: 883 K----RSMHAIIYLQ--CCFRRMMAKRELKKLKIEARSVERYKK 920
Score = 57.8 bits (138), Expect = 2e-07
Identities = 47/157 (29%), Positives = 85/157 (54%), Gaps = 14/157 (8%)
Query: 3018 KIAHEHFLMIKRHRAACL-IQAHYRGYKGRQVFLRQKSAALIIQKYIRAREAGKHERIKY 3076
++A+ L + RAAC+ IQ RG+ R+ +LR + AA+ +Q+Y+R +A + K+
Sbjct: 754 QVAYLEKLRADKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCY--AKF 811
Query: 3077 IEFKKSTVILQALVRGWLVRKRFLEQRAKIRLLH-----FTAAAYYHL-----NAVRIQR 3126
+ K+ I+Q R ++VR+R+ +RA +L F A Y AV IQ+
Sbjct: 812 LRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQK 871
Query: 3127 AYKLYLAVKNANKQVNSVICIQRWFRARLQEKRFIQK 3163
+ +LA + + ++++I +Q FR R+ KR ++K
Sbjct: 872 RVRGWLARTHYKRSMHAIIYLQCCFR-RMMAKRELKK 907
Score = 55.5 bits (132), Expect = 9e-07
Identities = 77/355 (21%), Positives = 158/355 (44%), Gaps = 41/355 (11%)
Query: 2457 LRKAAITIQSSYRRLMVKKKLQEMQRAAVLIQATFRMY--RTYITFQTWKHASILIQQHY 2514
LR A I IQ + R +++KK M++AA+ +Q R Y R Y F A+ +IQ+++
Sbjct: 766 LRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYW 825
Query: 2515 RTYRAAKLQRENYIRQWHSAVVIQAAYKGMKARQLLRE---KHKASIVIQSTYRMYRQYC 2571
R Y + R Y + + +V+Q+ +G AR R+ +HKA ++IQ R +
Sbjct: 826 RMY----VVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKA-VIIQKRVRGWLART 880
Query: 2572 FYQKLQWATKIIQEKYRANKKKQKV----FQHNELKKETCVQAGFQD--MNIKKQIQEQH 2625
Y++ A +Q +R K+++ + +++ + G ++ M +++++ EQ+
Sbjct: 881 HYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQN 940
Query: 2626 Q-AAIIIQKHCKAFKI-RKHYLHLRATVVSIQRRYRKLTAVRTQAVICIQSYYRGFKVRK 2683
+ +++K I LR+ + +Q + V T V+ +Q K+RK
Sbjct: 941 KDYKCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEE-AKVATGRVLSLQEEIA--KLRK 997
Query: 2684 DIQNMHRAATLIQSFYRMHRAKVDYETKKTAIVVIQNYYRLYVRVKTERKNFLAVQKSVR 2743
D++ I+ H + ET++ ++ N +K E++ + R
Sbjct: 998 DLEQTRSEKKCIEE----HADRYKQETEQ----LVSNLKEENTLLKQEKEAL-----NHR 1044
Query: 2744 TIQAAFRGMKVRQKLKNVSEEKMAAIVNQSALCCYRSKTQYEAVQSEGVMIQEWY 2798
+Q A +++ E+K+ Q L + +Y+ + +E ++E Y
Sbjct: 1045 IVQQA-------KEMTETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEERY 1092
Score = 50.8 bits (120), Expect = 2e-05
Identities = 49/212 (23%), Positives = 93/212 (43%), Gaps = 38/212 (17%)
Query: 3062 YIRAREAGKHERIKYIEFKKSTVILQALVRGWLVRKRFLEQR-AKIRLLHFT----AAAY 3116
+ RA + E+++ + + + + +Q +RGWL+RK++L R A I + + A Y
Sbjct: 749 FFRAGQVAYLEKLRADKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCY 808
Query: 3117 YHL-----NAVRIQRAYKLYLAVKNANKQVNSVICIQRWFRARLQEKRFIQKYHSIKKIE 3171
A IQ+ +++Y+ + + + I +Q + R L R+ +KI
Sbjct: 809 AKFLRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRY-------RKI- 860
Query: 3172 HEGQECLSQRNRAASVIQKAVRHFLLRKKQEKFTSGIIKIQALWRGYSWRKKNDCTKIKA 3231
R A +IQK VR +L R ++ II +Q +R +++ KI+A
Sbjct: 861 --------LREHKAVIIQKRVRGWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIEA 912
Query: 3232 ------------IRLSLQVVNREIREENKLYK 3251
+ + + R++ E+NK YK
Sbjct: 913 RSVERYKKLHIGMENKIMQLQRKVDEQNKDYK 944
Score = 50.4 bits (119), Expect = 3e-05
Identities = 42/178 (23%), Positives = 85/178 (47%), Gaps = 12/178 (6%)
Query: 2908 QIRSSVIIIQARSKGFIQKRKFQEIKNSTIKIQAMWRRYRAK---KYLCKVKAACKIQAW 2964
++R++ I IQ +G++ ++K+ ++ + I +Q R Y+A+ K+L + KAA IQ +
Sbjct: 765 KLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKY 824
Query: 2965 YRCWRAHKEYLAILKAVKIIQGCFYTKLERTRFLNV--RASAIIIQRKWRAILPAKIAHE 3022
+R + + Y A ++Q L R R+ + A+IIQ++ R L A
Sbjct: 825 WRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWL----ART 880
Query: 3023 HFLMIKRHRAACLIQAHYRGYKGRQVFLRQKSAALIIQKYIRAREAGKHERIKYIEFK 3080
H+ + A +Q +R ++ + K A +++Y + G +I ++ K
Sbjct: 881 HYK--RSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERY-KKLHIGMENKIMQLQRK 935
Score = 37.7 bits (86), Expect = 0.20
Identities = 30/102 (29%), Positives = 50/102 (49%), Gaps = 28/102 (27%)
Query: 1265 KEIRAARLIQTTWRKYKLKTDLKRHQEREKAARIIQLAVINFLAKQRLRK--RVNAALVI 1322
+ +AA +IQ WR Y ++ +R++ R A ++Q + FLA+ R RK R + A++I
Sbjct: 813 RRTKAATIIQKYWRMYVVR---RRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVII 869
Query: 1323 QKY-----------------------WRRVLAQRKLLMLKKE 1341
QK +RR++A+R+L LK E
Sbjct: 870 QKRVRGWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIE 911
>gi|156119615 myosin IXA [Homo sapiens]
Length = 2548
Score = 76.6 bits (187), Expect = 4e-13
Identities = 54/189 (28%), Positives = 98/189 (51%), Gaps = 31/189 (16%)
Query: 2249 IFRGKKARRHLK-MMHIAAT----LIQRRFRTLMMRRRFLSLKKTAILIQRKYRAHLCTK 2303
+F ++ R+HL+ ++H L+QR FR L+ R+ FL L++ +++IQR +R +L K
Sbjct: 1001 VFLKEQERQHLQDLLHQEVLRRIILLQRWFRVLLCRQHFLHLRQASVIIQRFWRNYLNQK 1060
Query: 2304 HHLQFLQVQNAVIKIQSSYRRWMIRKRMREMHRAATFIQSTFRMHRLHMRYQALKQASVV 2363
QV++A ++K M AA +Q+++R H RY L+ A++V
Sbjct: 1061 ------QVRDAA-----------VQKDAFVMASAAALLQASWRAHLERQRYLELRAAAIV 1103
Query: 2364 IQQQYQANRAAKLQRQHYLRQRHSAVILQAAFRGMKTRRHLKSMHSSATLIQSRFRSLLV 2423
IQQ++ R +Y R+ +A+ +QA ++ + + + L+QS R
Sbjct: 1104 IQQKW---------RDYYRRRHMAAICIQARWKAYRESKRYQEQRKKIILLQSTCRGFRA 1154
Query: 2424 RRRFISLKK 2432
R+RF +LK+
Sbjct: 1155 RQRFKALKE 1163
Score = 76.3 bits (186), Expect = 5e-13
Identities = 61/263 (23%), Positives = 126/263 (47%), Gaps = 30/263 (11%)
Query: 2259 LKMMHIAATLIQRRFRTLMMRR--RFLSLKKTAILIQRKYRAHLCTKH---HLQFLQVQN 2313
+K + A + RF +++ R R+ + +T + Q Y + + H L +N
Sbjct: 913 VKCIRSNAEKLPLRFSDVLVLRQLRYTGMLETVRIRQSGYSSKYSFQDFVSHFHVLLPRN 972
Query: 2314 AV---IKIQSSYRRWMIRKRMREMHRAATFIQSTFRMHRLHMRYQALKQASVVIQQQYQA 2370
+ IQ +R+ + ++ + F++ R H + +Q + + +++Q+ ++
Sbjct: 973 IIPSKFNIQDFFRKINLNPDNYQVGKTMVFLKEQERQHLQDLLHQEVLRRIILLQRWFRV 1032
Query: 2371 NRAAKLQRQHYLRQRHSAVILQAAFRGMKTRRHLKS---------MHSSATLIQSRFRSL 2421
L RQH+L R ++VI+Q +R ++ ++ M S+A L+Q+ +R+
Sbjct: 1033 ----LLCRQHFLHLRQASVIIQRFWRNYLNQKQVRDAAVQKDAFVMASAAALLQASWRAH 1088
Query: 2422 LVRRRFISLKKATIFVQRKYRATICAKHKLYQFLHLRKAAITIQSSYRRLMVKKKLQEMQ 2481
L R+R++ L+ A I +Q+K+R +H AAI IQ+ ++ K+ QE +
Sbjct: 1089 LERQRYLELRAAAIVIQQKWRDYYRRRH---------MAAICIQARWKAYRESKRYQEQR 1139
Query: 2482 RAAVLIQATFRMYRTYITFQTWK 2504
+ +L+Q+T R +R F+ K
Sbjct: 1140 KKIILLQSTCRGFRARQRFKALK 1162
Score = 72.8 bits (177), Expect = 6e-12
Identities = 44/156 (28%), Positives = 82/156 (52%), Gaps = 9/156 (5%)
Query: 1289 HQEREKAARIIQLAVINFLAKQRLRKRVNAALVIQKYWRRVLAQRKLLMLKKEKLEKVQN 1348
HQE + ++Q L +Q A+++IQ++WR L Q+++ +K V
Sbjct: 1016 HQEVLRRIILLQRWFRVLLCRQHFLHLRQASVIIQRFWRNYLNQKQVRDAAVQKDAFVMA 1075
Query: 1349 KAASLIQGYWRRYSTRQRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYL 1408
AA+L+Q WR + RQR+L+L+ +I++Q + R Y+R A + IQ W+AY
Sbjct: 1076 SAAALLQASWRAHLERQRYLELRAAAIVIQQKWR-----DYYRRRHMAAICIQARWKAY- 1129
Query: 1409 RRKQDQQRYEMLKSSTLIIQSMFRKWKQRKMQSQVK 1444
++ +RY+ + +++QS R ++ R+ +K
Sbjct: 1130 ---RESKRYQEQRKKIILLQSTCRGFRARQRFKALK 1162
Score = 69.3 bits (168), Expect = 6e-11
Identities = 47/164 (28%), Positives = 83/164 (50%), Gaps = 27/164 (16%)
Query: 1844 YQSVLQSIIKIQRWYRAYKTLHDTRTHFLKTKAAVISLQSAYRGWKVRKQIRREHQAALK 1903
+Q VL+ II +QRW+R R HFL + A + +Q +R + +KQ+R
Sbjct: 1016 HQEVLRRIILLQRWFRVLLC----RQHFLHLRQASVIIQRFWRNYLNQKQVRD------- 1064
Query: 1904 IQSAFRMAKAQKQFRLFKTAALVIQQNFRAWTAGRKQCMEYIELRHAVLVLQSMWKGKTL 1963
A QK + +AA ++Q ++RA ++ Y+ELR A +V+Q W
Sbjct: 1065 -------AAVQKDAFVMASAAALLQASWRAHLERQR----YLELRAAAIVIQQKW----- 1108
Query: 1964 RRQLQRQHKCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYRAY 2007
R +R+H AI IQ+ ++ + + K+++ +K +L+Q R +
Sbjct: 1109 RDYYRRRHMAAICIQARWKAYRESKRYQEQRKKIILLQSTCRGF 1152
Score = 68.9 bits (167), Expect = 8e-11
Identities = 52/188 (27%), Positives = 94/188 (50%), Gaps = 11/188 (5%)
Query: 1427 IQSMFRKWKQRKMQSQVKATVILQRAFREWHLRKQAKEE--NSAIIIQSWYRMHKELRKY 1484
IQ FRK QV T++ + HL+ +E I++Q W+R+ + +
Sbjct: 980 IQDFFRKINLNPDNYQVGKTMVFLKEQERQHLQDLLHQEVLRRIILLQRWFRVLLCRQHF 1039
Query: 1485 IYIRSCVVIIQKRFRCFQAQKLYKR---RKESIL--TIQKYYKAYLKGKIERTNYLQKRA 1539
+++R VIIQ+ +R + QK + +K++ + + +A + +ER YL+ RA
Sbjct: 1040 LHLRQASVIIQRFWRNYLNQKQVRDAAVQKDAFVMASAAALLQASWRAHLERQRYLELRA 1099
Query: 1540 AAIQLQAAFRRLKAHNLCRQIRAACVIQSYWRMRQDRVRFLNLKKTIIKFQAHVRKHQQR 1599
AAI +Q +R R+ AA IQ+ W+ ++ R+ +K II Q+ R + R
Sbjct: 1100 AAIVIQQKWRDYYR----RRHMAAICIQARWKAYRESKRYQEQRKKIILLQSTCRGFRAR 1155
Query: 1600 QKYKKMKK 1607
Q++K +K+
Sbjct: 1156 QRFKALKE 1163
Score = 67.8 bits (164), Expect = 2e-10
Identities = 55/234 (23%), Positives = 97/234 (41%), Gaps = 55/234 (23%)
Query: 2866 LQHYFRTWQTRKQFLLYRKAAVVLQNHYRAFLSAKHQRQVYLQIRSSVIIIQARSKGFIQ 2925
+Q +FR K V L+ R L Q ++ ++ +I++Q + +
Sbjct: 980 IQDFFRKINLNPDNYQVGKTMVFLKEQERQHL----QDLLHQEVLRRIILLQRWFRVLLC 1035
Query: 2926 KRKFQEIKNSTIKIQAMWRRYRAKKYLCKVKAACKIQAWYRCWRAHKEYLAILKAVKIIQ 2985
++ F ++ +++ IQ WR Y +K + R K+ + A ++Q
Sbjct: 1036 RQHFLHLRQASVIIQRFWRNYLNQKQV-------------RDAAVQKDAFVMASAAALLQ 1082
Query: 2986 GCFYTKLERTRFLNVRASAIIIQRKWRAILPAKIAHEHFLMIKRHRAACLIQAHYRGYKG 3045
+ LER R+L +RA+AI+IQ+KWR +RH AA IQA ++ Y+
Sbjct: 1083 ASWRAHLERQRYLELRAAAIVIQQKWRDYYR-----------RRHMAAICIQARWKAYR- 1130
Query: 3046 RQVFLRQKSAALIIQKYIRAREAGKHERIKYIEFKKSTVILQALVRGWLVRKRF 3099
E +Y E +K ++LQ+ RG+ R+RF
Sbjct: 1131 --------------------------ESKRYQEQRKKIILLQSTCRGFRARQRF 1158
Score = 66.6 bits (161), Expect = 4e-10
Identities = 41/142 (28%), Positives = 75/142 (52%), Gaps = 9/142 (6%)
Query: 2861 RAAITLQHYFRTWQTRKQFLLYRKAAVVLQNHYRAFLSAKHQRQVYLQ-----IRSSVII 2915
R I LQ +FR R+ FL R+A+V++Q +R +L+ K R +Q + S+ +
Sbjct: 1021 RRIILLQRWFRVLLCRQHFLHLRQASVIIQRFWRNYLNQKQVRDAAVQKDAFVMASAAAL 1080
Query: 2916 IQARSKGFIQKRKFQEIKNSTIKIQAMWRRYRAKKYLCKVKAACKIQAWYRCWRAHKEYL 2975
+QA + ++++++ E++ + I IQ WR Y ++++ AA IQA ++ +R K Y
Sbjct: 1081 LQASWRAHLERQRYLELRAAAIVIQQKWRDYYRRRHM----AAICIQARWKAYRESKRYQ 1136
Query: 2976 AILKAVKIIQGCFYTKLERTRF 2997
K + ++Q R RF
Sbjct: 1137 EQRKKIILLQSTCRGFRARQRF 1158
Score = 63.2 bits (152), Expect = 4e-09
Identities = 45/159 (28%), Positives = 73/159 (45%), Gaps = 23/159 (14%)
Query: 2622 QEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQRRYRKLTAVRTQAVICIQSYYRGFKV 2681
QE + I++Q+ + R+H+LHLR V IQR +R Q R V
Sbjct: 1017 QEVLRRIILLQRWFRVLLCRQHFLHLRQASVIIQRFWRNYLN---------QKQVRDAAV 1067
Query: 2682 RKDIQNMHRAATLIQSFYRMHRAKVDYETKKTAIVVIQNYYRLYVRVK------------ 2729
+KD M AA L+Q+ +R H + Y + A +VIQ +R Y R +
Sbjct: 1068 QKDAFVMASAAALLQASWRAHLERQRYLELRAAAIVIQQKWRDYYRRRHMAAICIQARWK 1127
Query: 2730 --TERKNFLAVQKSVRTIQAAFRGMKVRQKLKNVSEEKM 2766
E K + +K + +Q+ RG + RQ+ K + E+++
Sbjct: 1128 AYRESKRYQEQRKKIILLQSTCRGFRARQRFKALKEQRL 1166
Score = 62.8 bits (151), Expect = 6e-09
Identities = 39/147 (26%), Positives = 84/147 (57%), Gaps = 10/147 (6%)
Query: 1375 IILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQD-----QQRYEMLKSSTLIIQS 1429
I+LQ R+++ + A+V IQR WR YL +KQ Q+ ++ S+ ++Q+
Sbjct: 1024 ILLQRWFRVLLCRQHFLHLRQASVIIQRFWRNYLNQKQVRDAAVQKDAFVMASAAALLQA 1083
Query: 1430 MFRKWKQRKMQSQVKAT-VILQRAFREWHLRKQAKEENSAIIIQSWYRMHKELRKYIYIR 1488
+R +R+ +++A +++Q+ +R+++ R+ +AI IQ+ ++ ++E ++Y R
Sbjct: 1084 SWRAHLERQRYLELRAAAIVIQQKWRDYYRRRHM----AAICIQARWKAYRESKRYQEQR 1139
Query: 1489 SCVVIIQKRFRCFQAQKLYKRRKESIL 1515
++++Q R F+A++ +K KE L
Sbjct: 1140 KKIILLQSTCRGFRARQRFKALKEQRL 1166
Score = 60.8 bits (146), Expect = 2e-08
Identities = 43/156 (27%), Positives = 79/156 (50%), Gaps = 14/156 (8%)
Query: 1753 KAVISLQSYFRMRKARQYYLKMYKAIIVIQNYYHAYKAQVNQR-----KNFLQVKKAATC 1807
+ +I LQ +FR+ RQ++L + +A ++IQ ++ Y Q R K+ + AA
Sbjct: 1021 RRIILLQRWFRVLLCRQHFLHLRQASVIIQRFWRNYLNQKQVRDAAVQKDAFVMASAAAL 1080
Query: 1808 LQAAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRVKYQSVLQSIIKIQRWYRAYKTLHDT 1867
LQA++R + RQ + AA+ IQ +R Y Y+ + I IQ ++AY+
Sbjct: 1081 LQASWRAHLERQRYLELRAAAIVIQQKWRDY-----YRRRHMAAICIQARWKAYR----E 1131
Query: 1868 RTHFLKTKAAVISLQSAYRGWKVRKQIRREHQAALK 1903
+ + + +I LQS RG++ R++ + + L+
Sbjct: 1132 SKRYQEQRKKIILLQSTCRGFRARQRFKALKEQRLR 1167
Score = 59.7 bits (143), Expect = 5e-08
Identities = 50/225 (22%), Positives = 99/225 (44%), Gaps = 26/225 (11%)
Query: 2003 YYRAYSIGREQNHLYLKTKAAVV----TLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYK 2058
Y YS +H ++ ++ +Q +R + + K V ++ + R +
Sbjct: 952 YSSKYSFQDFVSHFHVLLPRNIIPSKFNIQDFFRKINLNPDNYQVGKTMVFLKEQERQHL 1011
Query: 2059 TKKKYATYRASAIIIQRWYRGIKITNHQHKEYLNLKKTAIKIQSVYRGIRVRRHIQH--- 2115
+ I++QRW+R + H +L+L++ ++ IQ +R ++ ++
Sbjct: 1012 QDLLHQEVLRRIILLQRWFRVLLCRQH----FLHLRQASVIIQRFWRNYLNQKQVRDAAV 1067
Query: 2116 ------MHRAATFIKAMFKMHQSRISYHTMRKAAIVIQVRCRAYYQGKMQREKYLTILKA 2169
M AA ++A ++ H R Y +R AAIVIQ + R YY R +++ A
Sbjct: 1068 QKDAFVMASAAALLQASWRAHLERQRYLELRAAAIVIQQKWRDYY-----RRRHM----A 1118
Query: 2170 VKVLQASFRGVRVRRTLRKMQTAATLIQSNYRRYRQQTYFNKLKK 2214
+QA ++ R + ++ + L+QS R +R + F LK+
Sbjct: 1119 AICIQARWKAYRESKRYQEQRKKIILLQSTCRGFRARQRFKALKE 1163
Score = 59.7 bits (143), Expect = 5e-08
Identities = 44/209 (21%), Positives = 95/209 (45%), Gaps = 22/209 (10%)
Query: 1654 HILTSVIKIQSYYRAYVSKKEFLSLKNATIKLQSTVKMKQTRKQYLHLRAAALFIQQCYR 1713
+I+ S IQ ++R + + + L+ + + + + +Q+ +R
Sbjct: 972 NIIPSKFNIQDFFRKINLNPDNYQVGKTMVFLKEQERQHLQDLLHQEVLRRIILLQRWFR 1031
Query: 1714 SKKIAAQKREEYMQMRESCIKLQAFVRGYLVRKQMR---------LQRKAVISLQSYFRM 1764
R+ ++ +R++ + +Q F R YL +KQ+R + A LQ+ +R
Sbjct: 1032 ----VLLCRQHFLHLRQASVIIQRFWRNYLNQKQVRDAAVQKDAFVMASAAALLQASWRA 1087
Query: 1765 RKARQYYLKMYKAIIVIQNYYHAYKAQVNQRKNFLQVKKAATCLQAAYRGYKVRQLIKQQ 1824
RQ YL++ A IVIQ + Y + + AA C+QA ++ Y+ + ++Q
Sbjct: 1088 HLERQRYLELRAAAIVIQQKWRDY---------YRRRHMAAICIQARWKAYRESKRYQEQ 1138
Query: 1825 SIAALKIQSAFRGYNKRVKYQSVLQSIIK 1853
+ +QS RG+ R +++++ + ++
Sbjct: 1139 RKKIILLQSTCRGFRARQRFKALKEQRLR 1167
Score = 59.3 bits (142), Expect = 6e-08
Identities = 52/214 (24%), Positives = 97/214 (45%), Gaps = 52/214 (24%)
Query: 1574 QDRVRFLNLK-------KTIIKFQAHVRKHQQRQKYKKMKKAAVIIQTHFRAYIFAMKVL 1626
QD R +NL KT++ + R+H Q ++++ + +++Q FR +
Sbjct: 981 QDFFRKINLNPDNYQVGKTMVFLKEQERQHLQDLLHQEVLRRIILLQRWFRVLL------ 1034
Query: 1627 ASYQKTRSAVIVLQSAYRGMQARKMYIHILTSVIKIQSYYRAYVSKKEF---------LS 1677
R+ ++H+ + + IQ ++R Y+++K+
Sbjct: 1035 ---------------------CRQHFLHLRQASVIIQRFWRNYLNQKQVRDAAVQKDAFV 1073
Query: 1678 LKNATIKLQSTVKMKQTRKQYLHLRAAALFIQQCYRSKKIAAQKREEYMQMRESCIKLQA 1737
+ +A LQ++ + R++YL LRAAA+ IQQ + R+ Y + + I +QA
Sbjct: 1074 MASAAALLQASWRAHLERQRYLELRAAAIVIQQKW---------RDYYRRRHMAAICIQA 1124
Query: 1738 FVRGYLVRKQMRLQRKAVISLQSYFRMRKARQYY 1771
+ Y K+ + QRK +I LQS R +ARQ +
Sbjct: 1125 RWKAYRESKRYQEQRKKIILLQSTCRGFRARQRF 1158
Score = 58.5 bits (140), Expect = 1e-07
Identities = 47/196 (23%), Positives = 90/196 (45%), Gaps = 37/196 (18%)
Query: 2459 KAAITIQSSYRRLMVKKKLQEMQRAAVLIQATFRMYRTYITFQTWKHASILIQQHYRTY- 2517
K + ++ R+ + QE+ R +L+Q FR+ F + AS++IQ+ +R Y
Sbjct: 998 KTMVFLKEQERQHLQDLLHQEVLRRIILLQRWFRVLLCRQHFLHLRQASVIIQRFWRNYL 1057
Query: 2518 -----RAAKLQRENYIRQWHSAVVIQAAYKGMKARQLLREKHKASIVIQSTYRMYRQYCF 2572
R A +Q++ ++ +A ++QA+++ RQ E A+IVIQ +R Y
Sbjct: 1058 NQKQVRDAAVQKDAFVMA-SAAALLQASWRAHLERQRYLELRAAAIVIQQKWRDY----- 1111
Query: 2573 YQKLQWATKIIQEKYRANKKKQKVFQHNELKKETCVQAGFQDMNIKKQIQEQHQAAIIIQ 2632
Y++ A IQ +++A ++ K+ QEQ + I++Q
Sbjct: 1112 YRRRHMAAICIQARWKAYRE-------------------------SKRYQEQRKKIILLQ 1146
Query: 2633 KHCKAFKIRKHYLHLR 2648
C+ F+ R+ + L+
Sbjct: 1147 STCRGFRARQRFKALK 1162
Score = 58.2 bits (139), Expect = 1e-07
Identities = 39/135 (28%), Positives = 69/135 (51%), Gaps = 17/135 (12%)
Query: 2234 QRYNKLRHSVIYIQAIFRGKKARRHLK---------MMHIAATLIQRRFRTLMMRRRFLS 2284
Q + LR + + IQ +R ++ ++ +M AA L+Q +R + R+R+L
Sbjct: 1037 QHFLHLRQASVIIQRFWRNYLNQKQVRDAAVQKDAFVMASAAALLQASWRAHLERQRYLE 1096
Query: 2285 LKKTAILIQRKYRAHLCTKHHLQFLQVQNAVIKIQSSYRRWMIRKRMREMHRAATFIQST 2344
L+ AI+IQ+K+R + +H A I IQ+ ++ + KR +E + +QST
Sbjct: 1097 LRAAAIVIQQKWRDYYRRRH--------MAAICIQARWKAYRESKRYQEQRKKIILLQST 1148
Query: 2345 FRMHRLHMRYQALKQ 2359
R R R++ALK+
Sbjct: 1149 CRGFRARQRFKALKE 1163
Score = 57.0 bits (136), Expect = 3e-07
Identities = 52/197 (26%), Positives = 89/197 (45%), Gaps = 19/197 (9%)
Query: 2517 YRAAKLQRENYIRQWHSAVVIQAAYKGMKARQLL-REKHKASIVIQSTYRMYRQYCFYQK 2575
+R L +NY Q +V + + LL +E + I++Q +R+ +
Sbjct: 984 FRKINLNPDNY--QVGKTMVFLKEQERQHLQDLLHQEVLRRIILLQRWFRVLLCRQHFLH 1041
Query: 2576 LQWATKIIQEKYRANKKKQKVFQHNELKKETCVQAGFQDMNIKKQIQEQHQAAIIIQKHC 2635
L+ A+ IIQ +R N QK + ++K+ V A AA ++Q
Sbjct: 1042 LRQASVIIQRFWR-NYLNQKQVRDAAVQKDAFVMAS---------------AAALLQASW 1085
Query: 2636 KAFKIRKHYLHLRATVVSIQRRYRKLTAVRTQAVICIQSYYRGFKVRKDIQNMHRAATLI 2695
+A R+ YL LRA + IQ+++R R A ICIQ+ ++ ++ K Q + L+
Sbjct: 1086 RAHLERQRYLELRAAAIVIQQKWRDYYRRRHMAAICIQARWKAYRESKRYQEQRKKIILL 1145
Query: 2696 QSFYRMHRAKVDYETKK 2712
QS R RA+ ++ K
Sbjct: 1146 QSTCRGFRARQRFKALK 1162
Score = 53.1 bits (126), Expect = 5e-06
Identities = 39/166 (23%), Positives = 75/166 (45%), Gaps = 27/166 (16%)
Query: 1972 KCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYRAYSIGREQNHLYLKTKAAVVTLQSAY 2031
K + ++ R H+Q + + + +L+Q+++R + HL + A V +Q +
Sbjct: 998 KTMVFLKEQERQHLQDLLHQEVLRRIILLQRWFRVLLCRQHFLHL----RQASVIIQRFW 1053
Query: 2032 RGMKVRKRIKDC---------NKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKI 2082
R +K+++D AA +Q+ +RA+ +++Y RA+AI+IQ+ +R
Sbjct: 1054 RNYLNQKQVRDAAVQKDAFVMASAAALLQASWRAHLERQRYLELRAAAIVIQQKWRDYYR 1113
Query: 2083 TNH--------------QHKEYLNLKKTAIKIQSVYRGIRVRRHIQ 2114
H + K Y +K I +QS RG R R+ +
Sbjct: 1114 RRHMAAICIQARWKAYRESKRYQEQRKKIILLQSTCRGFRARQRFK 1159
Score = 51.6 bits (122), Expect = 1e-05
Identities = 42/159 (26%), Positives = 76/159 (47%), Gaps = 26/159 (16%)
Query: 2792 VMIQEWYKASGLACSQEAEYHSQSRAAVTIQKAFCRMVTRKLETQKCAALRIQFFLQMAV 2851
+++Q W++ L C Q + Q A+V IQ+ + + +K AV
Sbjct: 1024 ILLQRWFRV--LLCRQHFLHLRQ--ASVIIQRFWRNYLNQKQVRDA------------AV 1067
Query: 2852 YRRRFVQQKRAAITLQHYFRTWQTRKQFLLYRKAAVVLQNHYRAFLSAKHQRQVYLQIRS 2911
+ FV AA+ LQ +R R+++L R AA+V+Q +R + +H
Sbjct: 1068 QKDAFVMASAAAL-LQASWRAHLERQRYLELRAAAIVIQQKWRDYYRRRHM--------- 1117
Query: 2912 SVIIIQARSKGFIQKRKFQEIKNSTIKIQAMWRRYRAKK 2950
+ I IQAR K + + +++QE + I +Q+ R +RA++
Sbjct: 1118 AAICIQARWKAYRESKRYQEQRKKIILLQSTCRGFRARQ 1156
Score = 51.2 bits (121), Expect = 2e-05
Identities = 44/139 (31%), Positives = 66/139 (47%), Gaps = 11/139 (7%)
Query: 3031 RAACLIQAHYRGYKGRQVFLRQKSAALIIQKYIRAREAGKHERIKYIE-----FKKSTVI 3085
R L+Q +R RQ FL + A++IIQ++ R K R ++ + +
Sbjct: 1021 RRIILLQRWFRVLLCRQHFLHLRQASVIIQRFWRNYLNQKQVRDAAVQKDAFVMASAAAL 1080
Query: 3086 LQALVRGWLVRKRFLEQRAKIRLLHFTAAAYY---HLNAVRIQRAYKLYLAVKNANKQVN 3142
LQA R L R+R+LE RA ++ YY H+ A+ IQ +K Y K +Q
Sbjct: 1081 LQASWRAHLERQRYLELRAAAIVIQQKWRDYYRRRHMAAICIQARWKAYRESKRYQEQRK 1140
Query: 3143 SVICIQ---RWFRARLQEK 3158
+I +Q R FRAR + K
Sbjct: 1141 KIILLQSTCRGFRARQRFK 1159
Score = 49.7 bits (117), Expect = 5e-05
Identities = 59/304 (19%), Positives = 131/304 (43%), Gaps = 30/304 (9%)
Query: 2092 NLKKTAIKIQSVYRGIRVRRHIQHMHRAATFIKAMFKMHQSRISYHTMRKAAIVIQVRCR 2151
N+ + IQ +R I + + + F+K + H + + + + I++Q
Sbjct: 972 NIIPSKFNIQDFFRKINLNPDNYQVGKTMVFLKEQERQHLQDLLHQEVLRRIILLQ---- 1027
Query: 2152 AYYQGKMQREKYLTILKAVKVLQASFRGVRVRRTLRK---------MQTAATLIQSNYRR 2202
+++ + R+ +L + +A ++Q +R ++ +R M +AA L+Q+++R
Sbjct: 1028 RWFRVLLCRQHFLHLRQASVIIQRFWRNYLNQKQVRDAAVQKDAFVMASAAALLQASWRA 1087
Query: 2203 YRQQTYFNKLKKITKTVQQRYWAMKERNIQFQRYNKLRH-SVIYIQAIFRGKKARRHLKM 2261
+ ++ + +L+ +QQ++ + Y + RH + I IQA ++ + + +
Sbjct: 1088 HLERQRYLELRAAAIVIQQKW----------RDYYRRRHMAAICIQARWKAYRESKRYQE 1137
Query: 2262 MHIAATLIQRRFRTLMMRRRFLSLKKTAILIQRKYRAHLCTKHHLQFLQVQNAVIKIQSS 2321
L+Q R R+RF +LK+ L + K L L++Q + S
Sbjct: 1138 QRKKIILLQSTCRGFRARQRFKALKEQR-LRETKPEVGLVNIKGYGSLEIQGS---DPSG 1193
Query: 2322 YRRWMIRKRMREMHRAATFIQSTFRMHRLHMRYQALKQASVVIQQQYQANRAAKLQRQHY 2381
+ R++ + + I+S R+ R LK++ Q++ Q+ LQ
Sbjct: 1194 WEDCSFDNRIKAIEECKSVIESN-RISR-ESSVDCLKESPNKQQERAQSQSGVDLQEDVL 1251
Query: 2382 LRQR 2385
+R+R
Sbjct: 1252 VRER 1255
Score = 37.0 bits (84), Expect = 0.34
Identities = 37/208 (17%), Positives = 90/208 (43%), Gaps = 29/208 (13%)
Query: 2672 IQSYYRGFKVRKDIQNMHRAATLIQSFYRMHRAKVDYETKKTAIVVIQNYYRLYVRVKTE 2731
IQ ++R + D + + ++ R H + ++ I+++Q ++R+ +
Sbjct: 980 IQDFFRKINLNPDNYQVGKTMVFLKEQERQHLQDLLHQEVLRRIILLQRWFRVLLC---- 1035
Query: 2732 RKNFLAVQKSVRTIQAAFRGMKVRQKLKNVSEEKMAAIVNQSALCCYRSKTQYEAVQSEG 2791
R++FL ++++ IQ +R ++++++ + +K A ++ +A
Sbjct: 1036 RQHFLHLRQASVIIQRFWRNYLNQKQVRDAAVQKDAFVMASAAAL--------------- 1080
Query: 2792 VMIQEWYKASGLACSQEAEYHSQSRAAVTIQKAFCRMVTRKLETQKCAALRIQFFLQMAV 2851
+AS A + Y AA+ IQ+ + R+ C R + + +
Sbjct: 1081 ------LQASWRAHLERQRYLELRAAAIVIQQKWRDYYRRRHMAAICIQARWKAYRE--- 1131
Query: 2852 YRRRFVQQKRAAITLQHYFRTWQTRKQF 2879
+R+ +Q++ I LQ R ++ R++F
Sbjct: 1132 -SKRYQEQRKKIILLQSTCRGFRARQRF 1158
Score = 34.3 bits (77), Expect = 2.2
Identities = 24/93 (25%), Positives = 42/93 (45%), Gaps = 14/93 (15%)
Query: 3144 VICIQRWFRARLQEKRFIQKYHSIKKIEHEGQECLSQRN--------------RAASVIQ 3189
+I +QRWFR L + F+ + I+ + L+Q+ AA+++Q
Sbjct: 1023 IILLQRWFRVLLCRQHFLHLRQASVIIQRFWRNYLNQKQVRDAAVQKDAFVMASAAALLQ 1082
Query: 3190 KAVRHFLLRKKQEKFTSGIIKIQALWRGYSWRK 3222
+ R L R++ + + I IQ WR Y R+
Sbjct: 1083 ASWRAHLERQRYLELRAAAIVIQQKWRDYYRRR 1115
>gi|122937345 myosin VB [Homo sapiens]
Length = 1848
Score = 75.9 bits (185), Expect = 7e-13
Identities = 45/153 (29%), Positives = 82/153 (53%), Gaps = 8/153 (5%)
Query: 1920 FKTAALVIQQNFRAWTAGRKQCMEYIELRHAVLVLQSMWKGKTLRRQLQ--RQHKCAIII 1977
F+TA ++IQ+ R W Q ++Y L+ A L LQ +G RR + R+ + A+++
Sbjct: 764 FRTATIMIQKTVRGWL----QKVKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVL 819
Query: 1978 QSYYRMHVQQKKWKIMKKAALLIQKYYRAYSIGREQNHLYLKTKAAVVTLQSAYRGMKVR 2037
Q +YRM ++ ++ +++AA++IQ + RA + R + ++ KA T+Q RG R
Sbjct: 820 QKHYRMQRARQAYQRVRRAAVVIQAFTRAMFVRRTYRQVLMEHKAT--TIQKHVRGWMAR 877
Query: 2038 KRIKDCNKAAVTIQSKYRAYKTKKKYATYRASA 2070
+ + AA+ IQ +R K +++ R A
Sbjct: 878 RHFQRLRDAAIVIQCAFRMLKARRELKALRIEA 910
Score = 68.9 bits (167), Expect = 8e-11
Identities = 76/323 (23%), Positives = 149/323 (46%), Gaps = 67/323 (20%)
Query: 2908 QIRSSVIIIQARSKGFIQKRKFQEIKNSTIKIQAMWRRYRAKK---YLCKVKAACKIQAW 2964
+ R++ I+IQ +G++QK K+ +K +T+ +Q R + A++ +L +++AA +Q
Sbjct: 763 KFRTATIMIQKTVRGWLQKVKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVLQKH 822
Query: 2965 YRCWRAHKEYLAILKAVKIIQGCFYTKLERTRFLNVRASAIIIQRKWRAILPAKIAHEHF 3024
YR RA + Y + +A +IQ +T+ A+ ++R +R +L EH
Sbjct: 823 YRMQRARQAYQRVRRAAVVIQA--FTR------------AMFVRRTYRQVL-----MEH- 862
Query: 3025 LMIKRHRAACLIQAHYRGYKGRQVFLRQKSAALIIQ---KYIRAR--------EAGKHER 3073
A IQ H RG+ R+ F R + AA++IQ + ++AR EA E
Sbjct: 863 -------KATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRMLKARRELKALRIEARSAEH 915
Query: 3074 IKYIEFKKSTVILQALVRGWLVRKRFLEQRAKIRLLHFTAAAYYHLNAVRIQRAYKLYLA 3133
+K + ++Q ++++ EQ + + L + + ++R K +
Sbjct: 916 LKRLNVGMENKVVQ-------LQRKIDEQNKEFKTLSEQLSVTTSTYTMEVERLKKELVH 968
Query: 3134 VKNANKQVNSVICIQRWFRARLQE-----KRFIQKYHSIKKI--EHEGQECLSQRNRAAS 3186
+ + + S+ RLQE + +Q+ HS +KI + +E R R A
Sbjct: 969 YQQSPGEDTSL---------RLQEEVESLRTELQRAHSERKILEDAHSREKDELRKRVAD 1019
Query: 3187 VIQKAVRHFLLRKKQEKFTSGII 3209
+ Q+ + LL+ ++E+ + I+
Sbjct: 1020 LEQE---NALLKDEKEQLNNQIL 1039
Score = 68.2 bits (165), Expect = 1e-10
Identities = 47/156 (30%), Positives = 79/156 (50%), Gaps = 4/156 (2%)
Query: 1616 FRAYIFAMKVLASYQKTRSAVIVLQSAYRGMQARKMYIHILTSVIKIQSYYRAYVSKK-- 1673
FRA A K R+A I++Q RG + Y + + + +Q Y R +++++
Sbjct: 748 FRAGQVAYLEKLRADKFRTATIMIQKTVRGWLQKVKYHRLKGATLTLQRYCRGHLARRLA 807
Query: 1674 EFLSLKNATIKLQSTVKMKQTRKQYLHLRAAALFIQQCYRSKKIAAQKREEYMQMRESCI 1733
E L A + LQ +M++ R+ Y +R AA+ IQ R+ + R+ M+ + + I
Sbjct: 808 EHLRRIRAAVVLQKHYRMQRARQAYQRVRRAAVVIQAFTRAMFVRRTYRQVLMEHKATTI 867
Query: 1734 KLQAFVRGYLVRKQMRLQRKAVISLQSYFRMRKARQ 1769
Q VRG++ R+ + R A I +Q FRM KAR+
Sbjct: 868 --QKHVRGWMARRHFQRLRDAAIVIQCAFRMLKARR 901
Score = 67.8 bits (164), Expect = 2e-10
Identities = 57/202 (28%), Positives = 100/202 (49%), Gaps = 14/202 (6%)
Query: 2969 RAHKEYLAILKAVKIIQGCFYTKLERTRFLNVRASAIIIQRKWRAILPAKIAHEHFLMIK 3028
RA K A + K ++G L++ ++ ++ + + +QR R L ++A EH ++
Sbjct: 760 RADKFRTATIMIQKTVRGW----LQKVKYHRLKGATLTLQRYCRGHLARRLA-EH---LR 811
Query: 3029 RHRAACLIQAHYRGYKGRQVFLRQKSAALIIQKYIRAREAGKHERIKYIEFKKSTVILQA 3088
R RAA ++Q HYR + RQ + R + AA++IQ + RA + R +E K +T+ Q
Sbjct: 812 RIRAAVVLQKHYRMQRARQAYQRVRRAAVVIQAFTRAMFVRRTYRQVLMEHKATTI--QK 869
Query: 3089 LVRGWLVRKRFLEQR---AKIRLLHFTAAAYYHLNAVRIQRAYKLYLAVKNANKQVNSVI 3145
VRGW+ R+ F R I+ A L A+RI+ +L N + N V+
Sbjct: 870 HVRGWMARRHFQRLRDAAIVIQCAFRMLKARRELKALRIEARSAEHLKRLNVGME-NKVV 928
Query: 3146 CIQRWFRARLQEKRFIQKYHSI 3167
+QR + +E + + + S+
Sbjct: 929 QLQRKIDEQNKEFKTLSEQLSV 950
Score = 67.8 bits (164), Expect = 2e-10
Identities = 55/213 (25%), Positives = 105/213 (49%), Gaps = 38/213 (17%)
Query: 1488 RSCVVIIQKRFRCFQAQKLYKRRKESILTIQKYYKAYLKGKIERTNYLQKRAAAIQLQAA 1547
R+ ++IQK R + + Y R K + LT+Q+Y + +L
Sbjct: 765 RTATIMIQKTVRGWLQKVKYHRLKGATLTLQRYCRGHLA--------------------- 803
Query: 1548 FRRLKAHNLCRQIRAACVIQSYWRMRQDRVRFLNLKKTIIKFQAHVRKHQQRQKYKK--M 1605
RRL H R+IRAA V+Q ++RM++ R + +++ + QA R R+ Y++ M
Sbjct: 804 -RRLAEH--LRRIRAAVVLQKHYRMQRARQAYQRVRRAAVVIQAFTRAMFVRRTYRQVLM 860
Query: 1606 KKAAVIIQTHFRAYIFAMKVLASYQKTRSAVIVLQSAYRGMQARKMYIHILTSVIKIQSY 1665
+ A IQ H R ++ +Q+ R A IV+Q A+R ++AR+ ++I++
Sbjct: 861 EHKATTIQKHVRGWM----ARRHFQRLRDAAIVIQCAFRMLKARRE-----LKALRIEAR 911
Query: 1666 YRAYVSKKEFLSLKNATIKLQSTVKMKQTRKQY 1698
++ K+ + ++N ++LQ K+ + K++
Sbjct: 912 SAEHL-KRLNVGMENKVVQLQR--KIDEQNKEF 941
Score = 65.9 bits (159), Expect = 7e-10
Identities = 49/185 (26%), Positives = 92/185 (49%), Gaps = 11/185 (5%)
Query: 2056 AYKTKKKYATYRASAIIIQRWYRGIKITNHQHKEYLNLKKTAIKIQSVYRGIRVRRHIQH 2115
AY K + +R + I+IQ+ RG Q +Y LK + +Q RG RR +H
Sbjct: 754 AYLEKLRADKFRTATIMIQKTVRGWL----QKVKYHRLKGATLTLQRYCRGHLARRLAEH 809
Query: 2116 MHR--AATFIKAMFKMHQSRISYHTMRKAAIVIQVRCRAYYQGKMQREKYLTILKAVKVL 2173
+ R AA ++ ++M ++R +Y +R+AA+VIQ RA + + R+ + + +
Sbjct: 810 LRRIRAAVVLQKHYRMQRARQAYQRVRRAAVVIQAFTRAMFVRRTYRQ--VLMEHKATTI 867
Query: 2174 QASFRGVRVRRTLRKMQTAATLIQSNYRRYRQQTYFNKLK---KITKTVQQRYWAMKERN 2230
Q RG RR ++++ AA +IQ +R + + L+ + + +++ M+ +
Sbjct: 868 QKHVRGWMARRHFQRLRDAAIVIQCAFRMLKARRELKALRIEARSAEHLKRLNVGMENKV 927
Query: 2231 IQFQR 2235
+Q QR
Sbjct: 928 VQLQR 932
Score = 65.9 bits (159), Expect = 7e-10
Identities = 46/170 (27%), Positives = 81/170 (47%), Gaps = 7/170 (4%)
Query: 2286 KKTAILIQRKYRAHLCTKHHLQFLQVQNAVIKIQSSYRRWMIRKRMREMHR--AATFIQS 2343
+ I+IQ+ R L +++ +++ A + +Q R + R+ + R AA +Q
Sbjct: 765 RTATIMIQKTVRGWL---QKVKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVLQK 821
Query: 2344 TFRMHRLHMRYQALKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAFRGMKTRRH 2403
+RM R YQ +++A+VVIQ +A + RQ + H A +Q RG RRH
Sbjct: 822 HYRMQRARQAYQRVRRAAVVIQAFTRAMFVRRTYRQ--VLMEHKATTIQKHVRGWMARRH 879
Query: 2404 LKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKHKLYQ 2453
+ + +A +IQ FR L RR +L+ + R + ++K+ Q
Sbjct: 880 FQRLRDAAIVIQCAFRMLKARRELKALRIEARSAEHLKRLNVGMENKVVQ 929
Score = 62.8 bits (151), Expect = 6e-09
Identities = 42/137 (30%), Positives = 76/137 (55%), Gaps = 8/137 (5%)
Query: 1702 RAAALFIQQCYRSKKIAAQKREEYMQMRESCIKLQAFVRGYLVRKQMRLQRK--AVISLQ 1759
R A + IQ+ R ++ +Y +++ + + LQ + RG+L R+ R+ A + LQ
Sbjct: 765 RTATIMIQKTVRGWL----QKVKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVLQ 820
Query: 1760 SYFRMRKARQYYLKMYKAIIVIQNYYHAYKAQVNQRKNFLQVKKAATCLQAAYRGYKVRQ 1819
++RM++ARQ Y ++ +A +VIQ + A + R+ ++ K AT +Q RG+ R+
Sbjct: 821 KHYRMQRARQAYQRVRRAAVVIQAFTRAMFVRRTYRQVLMEHK--ATTIQKHVRGWMARR 878
Query: 1820 LIKQQSIAALKIQSAFR 1836
++ AA+ IQ AFR
Sbjct: 879 HFQRLRDAAIVIQCAFR 895
Score = 62.4 bits (150), Expect = 8e-09
Identities = 47/154 (30%), Positives = 75/154 (48%), Gaps = 8/154 (5%)
Query: 1773 KMYKAIIVIQNYYHAYKAQVNQRKNFLQVKKAATCLQAAYRGYKVRQLIK--QQSIAALK 1830
K A I+IQ + Q+ + ++K A LQ RG+ R+L + ++ AA+
Sbjct: 763 KFRTATIMIQKTVRGWL----QKVKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVV 818
Query: 1831 IQSAFRGYNKRVKYQSVLQSIIKIQRWYRAYKTLHDTRTHFLKTKAAVISLQSAYRGWKV 1890
+Q +R R YQ V ++ + IQ + RA R ++ KA I Q RGW
Sbjct: 819 LQKHYRMQRARQAYQRVRRAAVVIQAFTRAMFVRRTYRQVLMEHKATTI--QKHVRGWMA 876
Query: 1891 RKQIRREHQAALKIQSAFRMAKAQKQFRLFKTAA 1924
R+ +R AA+ IQ AFRM KA+++ + + A
Sbjct: 877 RRHFQRLRDAAIVIQCAFRMLKARRELKALRIEA 910
Score = 62.4 bits (150), Expect = 8e-09
Identities = 44/149 (29%), Positives = 71/149 (47%), Gaps = 8/149 (5%)
Query: 1994 KKAALLIQKYYRAYSIGREQNHLYLKTKAAVVTLQSAYRGMKVRKRIKDCNK--AAVTIQ 2051
+ A ++IQK R + Q Y + K A +TLQ RG R+ + + AAV +Q
Sbjct: 765 RTATIMIQKTVRGWL----QKVKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVLQ 820
Query: 2052 SKYRAYKTKKKYATYRASAIIIQRWYRGIKITNHQHKEYLNLKKTAIKIQSVYRGIRVRR 2111
YR + ++ Y R +A++IQ + R + + + + K T IQ RG RR
Sbjct: 821 KHYRMQRARQAYQRVRRAAVVIQAFTRAMFVRRTYRQVLMEHKATT--IQKHVRGWMARR 878
Query: 2112 HIQHMHRAATFIKAMFKMHQSRISYHTMR 2140
H Q + AA I+ F+M ++R +R
Sbjct: 879 HFQRLRDAAIVIQCAFRMLKARRELKALR 907
Score = 61.6 bits (148), Expect = 1e-08
Identities = 45/161 (27%), Positives = 79/161 (49%), Gaps = 13/161 (8%)
Query: 2203 YRQQTYFNKLKKITKTVQQ--RYWAMKERNIQFQRYNKLRHSVIYIQAIFRGKKARR--- 2257
Y ++ +K + T +Q+ R W K + Y++L+ + + +Q RG ARR
Sbjct: 755 YLEKLRADKFRTATIMIQKTVRGWLQKVK------YHRLKGATLTLQRYCRGHLARRLAE 808
Query: 2258 HLKMMHIAATLIQRRFRTLMMRRRFLSLKKTAILIQRKYRAHLCTKHHLQFLQVQNAVIK 2317
HL+ + AA ++Q+ +R R+ + +++ A++IQ RA + + Q L A
Sbjct: 809 HLRRIR-AAVVLQKHYRMQRARQAYQRVRRAAVVIQAFTRAMFVRRTYRQVLMEHKATT- 866
Query: 2318 IQSSYRRWMIRKRMREMHRAATFIQSTFRMHRLHMRYQALK 2358
IQ R WM R+ + + AA IQ FRM + +AL+
Sbjct: 867 IQKHVRGWMARRHFQRLRDAAIVIQCAFRMLKARRELKALR 907
Score = 61.6 bits (148), Expect = 1e-08
Identities = 46/175 (26%), Positives = 89/175 (50%), Gaps = 26/175 (14%)
Query: 2778 YRSKTQYEAVQSEGVMIQEWYKASGLACSQEAEYHSQSRAAVTIQKAFCRMVTRKLETQK 2837
Y K + + ++ +MIQ+ + Q+ +YH A +T+Q+ +CR +
Sbjct: 755 YLEKLRADKFRTATIMIQKTVRG----WLQKVKYHRLKGATLTLQR-YCRGHLAR----- 804
Query: 2838 CAALRIQFFLQMAVYRRRFVQQKRAAITLQHYFRTWQTRKQFLLYRKAAVVLQNHYRAFL 2897
++A + RR RAA+ LQ ++R + R+ + R+AAVV+Q RA
Sbjct: 805 ----------RLAEHLRRI----RAAVVLQKHYRMQRARQAYQRVRRAAVVIQAFTRAMF 850
Query: 2898 SAKHQRQVYLQIRSSVIIIQARSKGFIQKRKFQEIKNSTIKIQAMWRRYRAKKYL 2952
+ RQV ++ +++ IQ +G++ +R FQ ++++ I IQ +R +A++ L
Sbjct: 851 VRRTYRQVLMEHKATT--IQKHVRGWMARRHFQRLRDAAIVIQCAFRMLKARREL 903
Score = 61.2 bits (147), Expect = 2e-08
Identities = 59/224 (26%), Positives = 104/224 (46%), Gaps = 31/224 (13%)
Query: 2272 RFRTLMMRRRFLSLKKTAILIQRKYRAHLCTKHHLQFLQVQNAVIKIQSSYRRWMIRKRM 2331
R+R L+ +R + K AI R +L K +F Q I ++ ++ + R
Sbjct: 706 RYRVLVKKRELANTDKKAIC--RSVLENLI-KDPDKF-QFGRTKIFFRAGQVAYLEKLRA 761
Query: 2332 REMHRAATFIQSTFRMHRLHMRYQALKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVIL 2391
+ A IQ T R ++Y LK A++ +Q+ + + A +L +LR+ +AV+L
Sbjct: 762 DKFRTATIMIQKTVRGWLQKVKYHRLKGATLTLQRYCRGHLARRLAE--HLRRIRAAVVL 819
Query: 2392 QAAFRGMKTRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKHKL 2451
Q +R + R+ + + +A +IQ+ R++ FV+R YR + +HK
Sbjct: 820 QKHYRMQRARQAYQRVRRAAVVIQAFTRAM--------------FVRRTYRQVLM-EHK- 863
Query: 2452 YQFLHLRKAAITIQSSYRRLMVKKKLQEMQRAAVLIQATFRMYR 2495
A TIQ R M ++ Q ++ AA++IQ FRM +
Sbjct: 864 ---------ATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRMLK 898
Score = 57.8 bits (138), Expect = 2e-07
Identities = 62/294 (21%), Positives = 123/294 (41%), Gaps = 33/294 (11%)
Query: 2416 SRFRSLLVRRRFISLKKATIFVQRKYRATICAKHKLYQFLHLRKAAITIQSSYRRLMVKK 2475
+R+R L+ +R + K I R + +QF + I ++ + K
Sbjct: 705 NRYRVLVKKRELANTDKKAIC--RSVLENLIKDPDKFQF---GRTKIFFRAGQVAYLEKL 759
Query: 2476 KLQEMQRAAVLIQATFRMYRTYITFQTWKHASILIQQHYRTYRAAKLQRENYIRQWHSAV 2535
+ + + A ++IQ T R + + + K A++ +Q++ R + A +L ++R+ +AV
Sbjct: 760 RADKFRTATIMIQKTVRGWLQKVKYHRLKGATLTLQRYCRGHLARRLAE--HLRRIRAAV 817
Query: 2536 VIQAAYKGMKARQLLREKHKASIVIQSTYRMYRQYCFYQKLQWATKIIQEKYRANKKKQK 2595
V+Q Y+ +ARQ + +A++VIQ+ R ++ YR Q
Sbjct: 818 VLQKHYRMQRARQAYQRVRRAAVVIQAFTR--------------AMFVRRTYR-----QV 858
Query: 2596 VFQHNELKKETCVQAGFQDMNIKKQIQEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQ 2655
+ +H K T +Q + ++ Q AAI+IQ + K R+ LR S +
Sbjct: 859 LMEH----KATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRMLKARRELKALRIEARSAE 914
Query: 2656 RRYRKLTAVRTQAVICIQSYYRGFKVRKDIQNMHRAATLIQSFYRMHRAKVDYE 2709
R + + V Q + + K+ + + ++ S Y M ++ E
Sbjct: 915 HLKRLNVGMENKVV---QLQRKIDEQNKEFKTLSEQLSVTTSTYTMEVERLKKE 965
Score = 57.8 bits (138), Expect = 2e-07
Identities = 60/260 (23%), Positives = 127/260 (48%), Gaps = 40/260 (15%)
Query: 1816 KVRQLIKQQSIAALKIQSAFRGYNKRVKYQSVLQSIIK---------IQRWYRAYKTLHD 1866
+ R L+K++ +A +K+ +SVL+++IK + ++RA + +
Sbjct: 706 RYRVLVKKRELA---------NTDKKAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAYL 756
Query: 1867 TRTHFLKTKAAVISLQSAYRGWKVRKQIRREHQAALKIQS------AFRMAKAQKQFRLF 1920
+ K + A I +Q RGW + + R A L +Q A R+A+ ++ R
Sbjct: 757 EKLRADKFRTATIMIQKTVRGWLQKVKYHRLKGATLTLQRYCRGHLARRLAEHLRRIR-- 814
Query: 1921 KTAALVIQQNFRAWTAGRKQCMEYIELRHAVLVLQSMWKGKTLR---RQLQRQHKCAIII 1977
AA+V+Q+++R A + Y +R A +V+Q+ + +R RQ+ +HK A I
Sbjct: 815 --AAVVLQKHYRMQRARQ----AYQRVRRAAVVIQAFTRAMFVRRTYRQVLMEHK-ATTI 867
Query: 1978 QSYYRMHVQQKKWKIMKKAALLIQKYYRAYSIGREQNHLYLKTKAAV----VTLQSAYRG 2033
Q + R + ++ ++ ++ AA++IQ +R RE L ++ ++A + + +
Sbjct: 868 QKHVRGWMARRHFQRLRDAAIVIQCAFRMLKARRELKALRIEARSAEHLKRLNVGMENKV 927
Query: 2034 MKVRKRIKDCNKAAVTIQSK 2053
++++++I + NK T+ +
Sbjct: 928 VQLQRKIDEQNKEFKTLSEQ 947
Score = 54.3 bits (129), Expect = 2e-06
Identities = 45/154 (29%), Positives = 75/154 (48%), Gaps = 19/154 (12%)
Query: 2627 AAIIIQKHCKAFKIRKHYLHLRATVVSIQRRYRKLTAVRT-------QAVICIQSYYRGF 2679
A I+IQK + + + Y L+ +++QR R A R +A + +Q +YR
Sbjct: 767 ATIMIQKTVRGWLQKVKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVLQKHYRMQ 826
Query: 2680 KVRKDIQNMHRAATLIQSFYRMHRAKVDY-----ETKKTAIVVIQNYYRLYVRVKTERKN 2734
+ R+ Q + RAA +IQ+F R + Y E K T I + +VR R++
Sbjct: 827 RARQAYQRVRRAAVVIQAFTRAMFVRRTYRQVLMEHKATTI-------QKHVRGWMARRH 879
Query: 2735 FLAVQKSVRTIQAAFRGMKVRQKLKNVSEEKMAA 2768
F ++ + IQ AFR +K R++LK + E +A
Sbjct: 880 FQRLRDAAIVIQCAFRMLKARRELKALRIEARSA 913
Score = 53.5 bits (127), Expect = 4e-06
Identities = 57/235 (24%), Positives = 106/235 (45%), Gaps = 24/235 (10%)
Query: 1361 YSTRQRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQRYEML 1420
Y + R K + +I++Q +R + Y R AT+T+QR+ R +L R+ + +
Sbjct: 755 YLEKLRADKFRTATIMIQKTVRGWLQKVKYHRLKGATLTLQRYCRGHLARRLAEHLRRI- 813
Query: 1421 KSSTLIIQSMFRKWKQRKMQSQV-KATVILQRAFREWHLR---KQAKEENSAIIIQSWYR 1476
+ +++Q +R + R+ +V +A V++Q R +R +Q E+ A IQ R
Sbjct: 814 -RAAVVLQKHYRMQRARQAYQRVRRAAVVIQAFTRAMFVRRTYRQVLMEHKATTIQKHVR 872
Query: 1477 MHKELRKYIYIRSCVVIIQKRFRCFQAQKLYKRRKESILTIQKYYKAYLKGKIERTNY-L 1535
R + +R ++IQ FR +A RR+ L I+ +LK R N +
Sbjct: 873 GWMARRHFQRLRDAAIVIQCAFRMLKA-----RRELKALRIEARSAEHLK----RLNVGM 923
Query: 1536 QKRAAAIQLQAAFRRLKAHNLCRQIRAACVIQSYWRMRQDRVRFLNLKKTIIKFQ 1590
+ + +Q + + + L Q+ V S + M +R LKK ++ +Q
Sbjct: 924 ENKVVQLQRKIDEQNKEFKTLSEQL---SVTTSTYTMEVER-----LKKELVHYQ 970
Score = 52.8 bits (125), Expect = 6e-06
Identities = 39/151 (25%), Positives = 75/151 (49%), Gaps = 5/151 (3%)
Query: 2765 KMAAIVNQSALCCYRSKTQYEAVQSEGVMIQEWYKASGLACSQEAEYHSQSRAAVTIQKA 2824
+ A I+ Q + + K +Y ++ + +Q + + G + AE+ + RAAV +QK
Sbjct: 765 RTATIMIQKTVRGWLQKVKYHRLKGATLTLQRYCR--GHLARRLAEHLRRIRAAVVLQKH 822
Query: 2825 FCRMVTRKL-ETQKCAALRIQFFLQMAVYRRRFVQ--QKRAAITLQHYFRTWQTRKQFLL 2881
+ R+ + + AA+ IQ F + RR + Q + A T+Q + R W R+ F
Sbjct: 823 YRMQRARQAYQRVRRAAVVIQAFTRAMFVRRTYRQVLMEHKATTIQKHVRGWMARRHFQR 882
Query: 2882 YRKAAVVLQNHYRAFLSAKHQRQVYLQIRSS 2912
R AA+V+Q +R + + + + ++ RS+
Sbjct: 883 LRDAAIVIQCAFRMLKARRELKALRIEARSA 913
Score = 52.8 bits (125), Expect = 6e-06
Identities = 40/176 (22%), Positives = 80/176 (45%), Gaps = 16/176 (9%)
Query: 2556 ASIVIQSTYRMYRQYCFYQKLQWATKIIQEKYRANKKKQKVFQHNELKKETCVQAGFQDM 2615
A+I+IQ T R + Q Y +L+ AT +Q R + ++ ++ +Q ++
Sbjct: 767 ATIMIQKTVRGWLQKVKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVLQKHYRMQ 826
Query: 2616 NIKKQIQEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQRRYRKLTAVRTQAVICIQSY 2675
++ Q +AA++IQ +A +R R YR++ + IQ +
Sbjct: 827 RARQAYQRVRRAAVVIQAFTRAMFVR--------------RTYRQV--LMEHKATTIQKH 870
Query: 2676 YRGFKVRKDIQNMHRAATLIQSFYRMHRAKVDYETKKTAIVVIQNYYRLYVRVKTE 2731
RG+ R+ Q + AA +IQ +RM +A+ + + + ++ RL V ++ +
Sbjct: 871 VRGWMARRHFQRLRDAAIVIQCAFRMLKARRELKALRIEARSAEHLKRLNVGMENK 926
Score = 52.4 bits (124), Expect = 8e-06
Identities = 49/212 (23%), Positives = 97/212 (45%), Gaps = 38/212 (17%)
Query: 3062 YIRAREAGKHERIKYIEFKKSTVILQALVRGWLVRKRFLEQRAKIRLL------HFTAAA 3115
+ RA + E+++ +F+ +T+++Q VRGWL + ++ + L H
Sbjct: 747 FFRAGQVAYLEKLRADKFRTATIMIQKTVRGWLQKVKYHRLKGATLTLQRYCRGHLARRL 806
Query: 3116 YYHLNAVR----IQRAYKLYLAVKNANKQVNSVICIQRWFRARLQEKRFIQKYHSIKKIE 3171
HL +R +Q+ Y++ A + + + + IQ + RA F+++ + +E
Sbjct: 807 AEHLRRIRAAVVLQKHYRMQRARQAYQRVRRAAVVIQAFTRA-----MFVRRTYRQVLME 861
Query: 3172 HEGQECLSQRNRAASVIQKAVRHFLLRKKQEKFTSGIIKIQALWRGYSWRKKNDCTKIKA 3231
H+ A+ IQK VR ++ R+ ++ I IQ +R R++ +I+A
Sbjct: 862 HK-----------ATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRMLKARRELKALRIEA 910
Query: 3232 ------IRLSLQVVN------REIREENKLYK 3251
RL++ + N R+I E+NK +K
Sbjct: 911 RSAEHLKRLNVGMENKVVQLQRKIDEQNKEFK 942
>gi|153945715 myosin VC [Homo sapiens]
Length = 1742
Score = 71.2 bits (173), Expect = 2e-11
Identities = 97/424 (22%), Positives = 189/424 (44%), Gaps = 56/424 (13%)
Query: 1668 AYVSKKEFLSLKNATIKLQSTVKMKQTRKQYLHLRAAALFIQQCYRSKKIAAQKREEYMQ 1727
AY+ K L+ + + +Q ++ RK++L R AAL IQQ +R ++ +K +
Sbjct: 746 AYLEKLRLDKLRQSCVMVQKHMRGWLQRKKFLRERRAALIIQQYFRGQQ-TVRKAITAVA 804
Query: 1728 MRE--SCIKLQAFVRGYLVRKQMRLQRKAVISLQSYFRMRKARQYYLKM---YKAIIVIQ 1782
++E + I +Q RGYLVR +L R A I++Q+Y R AR+ Y KM +KA+I +Q
Sbjct: 805 LKEAWAAIIIQKHCRGYLVRSLYQLIRMATITMQAYSRGFLARRRYRKMLEEHKAVI-LQ 863
Query: 1783 NYYHAYKAQVNQRKNFLQVKKAATCLQAAYRGYKVRQLIKQQS------IAALKIQSAFR 1836
Y A+ A R+ F +++ +Q YR ++++ ++ Q+ + L +A R
Sbjct: 864 KYARAWLA----RRRFQSIRRFVLNIQLTYRVQRLQKKLEDQNKENHGLVEKLTSLAALR 919
Query: 1837 G--YNKRVKYQSVLQSIIKIQRWY----RAYKTLHDTRTHFLKTKAAVISLQSAYRGWKV 1890
K K ++ L+ +R Y + Y+ + + L+ + + Q K+
Sbjct: 920 AGDVEKIQKLEAELEKAATHRRNYEEKGKRYRDAVEEKLAKLQKHNSELETQKEQIQLKL 979
Query: 1891 RKQIR--REHQAALKIQSAFRMAKAQKQFRLFKTAALVIQQNFRAWTAGRKQCMEYIELR 1948
+++ +E L Q + K ++Q L + + + Q++ K+ E L+
Sbjct: 980 QEKTEELKEKMDNLTKQLFDDVQKEERQRMLLEKSFELKTQDYEKQIQSLKE--EIKALK 1037
Query: 1949 HAVLVLQSMWKGK-----TLRRQLQRQHKCAIIIQSYYR-------------MHVQQKKW 1990
+ LQ + +G+ L+ ++ R K I + + HVQ +K
Sbjct: 1038 DEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIELLQAQKIDVEKHVQSQKR 1097
Query: 1991 KIMKKAALLIQKYYRAYSIGREQNHLYLKTKAAV---VTLQSAYRGMKVRKRI------- 2040
++ +K + + ++ +Y I ++ L ++ + L AY G+K R+
Sbjct: 1098 EMREKMSEITKQLLESYDIEDVRSRLSVEDLEHLNEDGELWFAYEGLKKATRVLESHFQS 1157
Query: 2041 -KDC 2043
KDC
Sbjct: 1158 QKDC 1161
Score = 68.6 bits (166), Expect = 1e-10
Identities = 58/238 (24%), Positives = 116/238 (48%), Gaps = 14/238 (5%)
Query: 1575 DRVRFLNLKKTIIKFQAHVRKHQQRQKYKKMKKAAVIIQTHFRAYIFAMKVLASYQ-KTR 1633
+++R L+++ + Q H+R QR+K+ + ++AA+IIQ +FR K + + K
Sbjct: 749 EKLRLDKLRQSCVMVQKHMRGWLQRKKFLRERRAALIIQQYFRGQQTVRKAITAVALKEA 808
Query: 1634 SAVIVLQSAYRGMQARKMYIHILTSVIKIQSYYRAYVSKKEFLSL--KNATIKLQSTVKM 1691
A I++Q RG R +Y I + I +Q+Y R +++++ + + ++ + LQ +
Sbjct: 809 WAAIIIQKHCRGYLVRSLYQLIRMATITMQAYSRGFLARRRYRKMLEEHKAVILQKYARA 868
Query: 1692 KQTRKQYLHLRAAALFIQQCYR----SKKIAAQKREEYMQMRESCIKLQAFVRGYLVRKQ 1747
R+++ +R L IQ YR KK+ Q +E + + + + A +R V K
Sbjct: 869 WLARRRFQSIRRFVLNIQLTYRVQRLQKKLEDQNKENHGLVEK--LTSLAALRAGDVEKI 926
Query: 1748 MRLQ---RKAVISLQSYFRMRKARQYYLKMYKAIIVIQNYYHAYKAQVNQRKNFLQVK 1802
+L+ KA ++Y K ++Y + + + +Q + + Q Q + LQ K
Sbjct: 927 QKLEAELEKAATHRRNY--EEKGKRYRDAVEEKLAKLQKHNSELETQKEQIQLKLQEK 982
Score = 66.6 bits (161), Expect = 4e-10
Identities = 47/190 (24%), Positives = 98/190 (51%), Gaps = 28/190 (14%)
Query: 1712 YRSKKIAAQKREEYMQMRESCIKLQAFVRGYLVRKQMRLQRKAVISLQSYFRMRKARQYY 1771
+R+ ++A ++ ++R+SC+ +Q +RG+L RK+ +R+A + +Q YFR ++
Sbjct: 740 FRAGQVAYLEKLRLDKLRQSCVMVQKHMRGWLQRKKFLRERRAALIIQQYFRGQQT---- 795
Query: 1772 LKMYKAIIVIQNYYHAYKAQVNQRKNFLQVKKAATCLQAAYRGYKVRQLIKQQSIAALKI 1831
+ KAI + L+ AA +Q RGY VR L + +A + +
Sbjct: 796 --VRKAITAVA----------------LKEAWAAIIIQKHCRGYLVRSLYQLIRMATITM 837
Query: 1832 QSAFRGYNKRVKYQSVLQ--SIIKIQRWYRAYKTLHDTRTHFLKTKAAVISLQSAYRGWK 1889
Q+ RG+ R +Y+ +L+ + +Q++ RA+ R F + V+++Q YR +
Sbjct: 838 QAYSRGFLARRRYRKMLEEHKAVILQKYARAWL----ARRRFQSIRRFVLNIQLTYRVQR 893
Query: 1890 VRKQIRREHQ 1899
++K++ +++
Sbjct: 894 LQKKLEDQNK 903
Score = 62.4 bits (150), Expect = 8e-09
Identities = 45/149 (30%), Positives = 80/149 (53%), Gaps = 11/149 (7%)
Query: 2352 MRYQALKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAFRGMKTRRHLKSMHS-- 2409
+R L+Q+ V++Q+ + LQR+ +LR+R +A+I+Q FRG +T R + +
Sbjct: 751 LRLDKLRQSCVMVQKHMRG----WLQRKKFLRERRAALIIQQYFRGQQTVRKAITAVALK 806
Query: 2410 ---SATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKHKLYQFLHLRKAAITIQS 2466
+A +IQ R LVR + ++ ATI +Q Y A+ + + L KA I +Q
Sbjct: 807 EAWAAIIIQKHCRGYLVRSLYQLIRMATITMQ-AYSRGFLARRRYRKMLEEHKAVI-LQK 864
Query: 2467 SYRRLMVKKKLQEMQRAAVLIQATFRMYR 2495
R + +++ Q ++R + IQ T+R+ R
Sbjct: 865 YARAWLARRRFQSIRRFVLNIQLTYRVQR 893
Score = 61.6 bits (148), Expect = 1e-08
Identities = 50/195 (25%), Positives = 93/195 (47%), Gaps = 28/195 (14%)
Query: 1853 KIQRWYRAYKTLHDTRTHFLKTKAAVISLQSAYRGWKVRKQIRREHQAALKIQSAFRMAK 1912
K + ++RA + + + K + + + +Q RGW RK+ RE +AAL IQ FR
Sbjct: 735 KTKIFFRAGQVAYLEKLRLDKLRQSCVMVQKHMRGWLQRKKFLRERRAALIIQQYFR--- 791
Query: 1913 AQKQFRLFKTAALVIQQNFRAWTAGRKQCMEYIELRHAVLVLQSMWKGKTLRRQLQRQHK 1972
Q+ R TA + + AW A +++Q +G +R Q
Sbjct: 792 GQQTVRKAITAVALKE----AW---------------AAIIIQKHCRGYLVRSLYQLIRM 832
Query: 1973 CAIIIQSYYRMHVQQKKWKIM--KKAALLIQKYYRAYSIGREQNHLYLKTKAAVVTLQSA 2030
I +Q+Y R + +++++ M + A+++QKY RA+ R + + V+ +Q
Sbjct: 833 ATITMQAYSRGFLARRRYRKMLEEHKAVILQKYARAWLARRR----FQSIRRFVLNIQLT 888
Query: 2031 YRGMKVRKRIKDCNK 2045
YR +++K+++D NK
Sbjct: 889 YRVQRLQKKLEDQNK 903
Score = 60.8 bits (146), Expect = 2e-08
Identities = 46/174 (26%), Positives = 88/174 (50%), Gaps = 10/174 (5%)
Query: 2822 QKAFCRMVTRKL----ETQKCAALRIQFFLQMAVY--RRRFVQQKRAAITLQHYFRTWQT 2875
+K C++V +L + +I F Y + R + +++ + +Q + R W
Sbjct: 713 KKEVCKVVLHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRLDKLRQSCVMVQKHMRGWLQ 772
Query: 2876 RKQFLLYRKAAVVLQNHYRAFLSA-KHQRQVYLQIRSSVIIIQARSKGFIQKRKFQEIKN 2934
RK+FL R+AA+++Q ++R + K V L+ + IIIQ +G++ + +Q I+
Sbjct: 773 RKKFLRERRAALIIQQYFRGQQTVRKAITAVALKEAWAAIIIQKHCRGYLVRSLYQLIRM 832
Query: 2935 STIKIQAMWRRYRAKKYLCKV---KAACKIQAWYRCWRAHKEYLAILKAVKIIQ 2985
+TI +QA R + A++ K+ A +Q + R W A + + +I + V IQ
Sbjct: 833 ATITMQAYSRGFLARRRYRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQ 886
Score = 60.5 bits (145), Expect = 3e-08
Identities = 63/250 (25%), Positives = 110/250 (44%), Gaps = 56/250 (22%)
Query: 1304 INFLAKQRLRKRVNAALVIQKYWRRVLAQRKLLMLKKEKLEKVQNKAASLIQGYWRRYST 1363
+ +L K RL K + +++QK+ R L ++K L + +AA +IQ Y+R T
Sbjct: 745 VAYLEKLRLDKLRQSCVMVQKHMRGWLQRKKFLR---------ERRAALIIQQYFRGQQT 795
Query: 1364 RQRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQRYEMLKSS 1423
+R I + K WA + IQ+H R YL R Y++++ +
Sbjct: 796 -----------------VRKAITAVALKE-AWAAIIIQKHCRGYLVRSL----YQLIRMA 833
Query: 1424 TLIIQSMFRKWKQRKMQSQVKATVILQRAFREWHLRKQAKEENSAIIIQSWYRMHKELRK 1483
T+ +Q+ R + R+ ++ EE+ A+I+Q + R R+
Sbjct: 834 TITMQAYSRGFLARRRY-------------------RKMLEEHKAVILQKYARAWLARRR 874
Query: 1484 YIYIRSCVVIIQKRFRCFQAQ-KLYKRRKESILTIQKY--YKAYLKGKIERTNYLQKRAA 1540
+ IR V+ IQ +R + Q KL + KE+ ++K A G +E+ +QK A
Sbjct: 875 FQSIRRFVLNIQLTYRVQRLQKKLEDQNKENHGLVEKLTSLAALRAGDVEK---IQKLEA 931
Query: 1541 AIQLQAAFRR 1550
++ A RR
Sbjct: 932 ELEKAATHRR 941
Score = 60.1 bits (144), Expect = 4e-08
Identities = 54/178 (30%), Positives = 86/178 (48%), Gaps = 21/178 (11%)
Query: 2974 YLAILKAVKIIQGCFYTK------LERTRFLNVRASAIIIQRKWRAILPAKIAHEHFLMI 3027
YL L+ K+ Q C + L+R +FL R +A+IIQ+ +R + A + +
Sbjct: 747 YLEKLRLDKLRQSCVMVQKHMRGWLQRKKFLRERRAALIIQQYFRGQQTVRKAIT-AVAL 805
Query: 3028 KRHRAACLIQAHYRGYKGRQVFLRQKSAALIIQKYIRAREAGKHERIKYIEFKKSTVILQ 3087
K AA +IQ H RGY R ++ + A + +Q Y R A + R K +E K+ VILQ
Sbjct: 806 KEAWAAIIIQKHCRGYLVRSLYQLIRMATITMQAYSRGFLARRRYR-KMLEEHKA-VILQ 863
Query: 3088 ALVRGWLVRKRFLEQRAKIRLLHFTAAAYYHLNAVRIQRAYKLYLAVKNANKQVNSVI 3145
R WL R+RF R + + T R+QR K +++ NK+ + ++
Sbjct: 864 KYARAWLARRRFQSIRRFVLNIQLT---------YRVQRLQK---KLEDQNKENHGLV 909
Score = 57.8 bits (138), Expect = 2e-07
Identities = 59/247 (23%), Positives = 115/247 (46%), Gaps = 33/247 (13%)
Query: 3018 KIAHEHFLMIKRHRAAC-LIQAHYRGYKGRQVFLRQKSAALIIQKYIRAREAGKHERIKY 3076
++A+ L + + R +C ++Q H RG+ R+ FLR++ AALIIQ+Y R ++ + + I
Sbjct: 744 QVAYLEKLRLDKLRQSCVMVQKHMRGWLQRKKFLRERRAALIIQQYFRGQQTVR-KAITA 802
Query: 3077 IEFKK--STVILQALVRGWLVRKRFLEQRAKIRLLHFTAAAYYHLNAVRIQRAYKLYLAV 3134
+ K+ + +I+Q RG+LVR + IR+ T AY +R Y+ L
Sbjct: 803 VALKEAWAAIIIQKHCRGYLVRSLY----QLIRMATITMQAY--SRGFLARRRYRKML-- 854
Query: 3135 KNANKQVNSVICIQRWFRARLQEKRF---------IQKYHSIKKIEHEGQECLSQRNRAA 3185
+ + + +Q++ RA L +RF IQ + +++++ + ++ Q
Sbjct: 855 -----EEHKAVILQKYARAWLARRRFQSIRRFVLNIQLTYRVQRLQKKLED---QNKENH 906
Query: 3186 SVIQKAVRHFLLR----KKQEKFTSGIIKIQALWRGYSWRKKNDCTKIKAIRLSLQVVNR 3241
+++K LR +K +K + + K R Y + K ++ LQ N
Sbjct: 907 GLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRYRDAVEEKLAKLQKHNS 966
Query: 3242 EIREENK 3248
E+ + +
Sbjct: 967 ELETQKE 973
Score = 55.5 bits (132), Expect = 9e-07
Identities = 41/160 (25%), Positives = 81/160 (50%), Gaps = 14/160 (8%)
Query: 2203 YRQQTYFNKLKKITKTVQQ--RYWAMKERNIQFQRYNKLRHSVIYIQAIFRGKKA-RRHL 2259
Y ++ +KL++ VQ+ R W +Q +++ + R + + IQ FRG++ R+ +
Sbjct: 747 YLEKLRLDKLRQSCVMVQKHMRGW------LQRKKFLRERRAALIIQQYFRGQQTVRKAI 800
Query: 2260 KMMHI----AATLIQRRFRTLMMRRRFLSLKKTAILIQRKYRAHLCTKHHLQFLQVQNAV 2315
+ + AA +IQ+ R ++R + ++ I +Q R L + + + L+ AV
Sbjct: 801 TAVALKEAWAAIIIQKHCRGYLVRSLYQLIRMATITMQAYSRGFLARRRYRKMLEEHKAV 860
Query: 2316 IKIQSSYRRWMIRKRMREMHRAATFIQSTFRMHRLHMRYQ 2355
I +Q R W+ R+R + + R IQ T+R+ RL + +
Sbjct: 861 I-LQKYARAWLARRRFQSIRRFVLNIQLTYRVQRLQKKLE 899
Score = 55.5 bits (132), Expect = 9e-07
Identities = 40/151 (26%), Positives = 74/151 (49%), Gaps = 34/151 (22%)
Query: 2832 KLETQKCAALRIQFFLQMAVYRRRFVQQKRAAITLQHYFRTWQTRKQF-----LLYRKAA 2886
+L+ + + + +Q ++ + R++F++++RAA+ +Q YFR QT ++ L AA
Sbjct: 752 RLDKLRQSCVMVQKHMRGWLQRKKFLRERRAALIIQQYFRGQQTVRKAITAVALKEAWAA 811
Query: 2887 VVLQNHYRAFLSAKHQRQVYLQIRSSVIIIQARSKGFIQKRK------------------ 2928
+++Q H R +L R +Y IR + I +QA S+GF+ +R+
Sbjct: 812 IIIQKHCRGYLV----RSLYQLIRMATITMQAYSRGFLARRRYRKMLEEHKAVILQKYAR 867
Query: 2929 -------FQEIKNSTIKIQAMWRRYRAKKYL 2952
FQ I+ + IQ +R R +K L
Sbjct: 868 AWLARRRFQSIRRFVLNIQLTYRVQRLQKKL 898
Score = 54.3 bits (129), Expect = 2e-06
Identities = 43/169 (25%), Positives = 79/169 (46%), Gaps = 18/169 (10%)
Query: 2555 KASIVIQSTYRMYRQYCFYQKLQWATKIIQEKYRANKKKQKVFQHNELKKETCVQAGFQ- 2613
K I ++ Y + KL+ + ++Q+ R +++K + E + +Q F+
Sbjct: 735 KTKIFFRAGQVAYLEKLRLDKLRQSCVMVQKHMRGWLQRKKFLR--ERRAALIIQQYFRG 792
Query: 2614 DMNIKKQIQ----EQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQ---------RRYRK 2660
++K I ++ AAIIIQKHC+ + +R Y +R +++Q RRYRK
Sbjct: 793 QQTVRKAITAVALKEAWAAIIIQKHCRGYLVRSLYQLIRMATITMQAYSRGFLARRRYRK 852
Query: 2661 LTAVRTQAVICIQSYYRGFKVRKDIQNMHRAATLIQSFYRMHRAKVDYE 2709
+ + + +Q Y R + R+ Q++ R IQ YR+ R + E
Sbjct: 853 M--LEEHKAVILQKYARAWLARRRFQSIRRFVLNIQLTYRVQRLQKKLE 899
Score = 53.5 bits (127), Expect = 4e-06
Identities = 44/202 (21%), Positives = 90/202 (44%), Gaps = 30/202 (14%)
Query: 1412 QDQQRYEMLKSSTLIIQSMFRKWKQRKMQSQVKATVILQRAFREWHLRKQ-AKEENSAII 1470
QD +Y+ K+ ++ ++ ++ V++Q+ R W RK+ +E +A+I
Sbjct: 726 QDSNQYQFGKTKIFFRAGQVAYLEKLRLDKLRQSCVMVQKHMRGWLQRKKFLRERRAALI 785
Query: 1471 IQSWYRMHKELRKYIYIRS-----CVVIIQKRFRCFQAQKLYKRRKESILTIQKYYKAYL 1525
IQ ++R + +RK I + +IIQK R + + LY+ + + +T+Q Y + +L
Sbjct: 786 IQQYFRGQQTVRKAITAVALKEAWAAIIIQKHCRGYLVRSLYQLIRMATITMQAYSRGFL 845
Query: 1526 KGKIERTNYLQKRAAAIQLQAAFRRLKAHNLCRQIRAACVIQSYWRMRQDRVRFLNLKKT 1585
+ R + L+ H A ++Q Y R R RF ++++
Sbjct: 846 ARRRYR-----------------KMLEEHK-------AVILQKYARAWLARRRFQSIRRF 881
Query: 1586 IIKFQAHVRKHQQRQKYKKMKK 1607
++ Q R + ++K + K
Sbjct: 882 VLNIQLTYRVQRLQKKLEDQNK 903
Score = 53.5 bits (127), Expect = 4e-06
Identities = 65/283 (22%), Positives = 134/283 (47%), Gaps = 26/283 (9%)
Query: 2368 YQANRAAKLQRQHYLRQRHSAVILQAAFRGMKTRRHLKSMHSSATLIQSRFRSLLVRRRF 2427
++A + A L++ + R S V++Q RG R+ +A +IQ FR R+
Sbjct: 740 FRAGQVAYLEKLRLDKLRQSCVMVQKHMRGWLQRKKFLRERRAALIIQQYFRGQQTVRKA 799
Query: 2428 I---SLKK--ATIFVQRKYRATICAKHKLYQFLHLRKAAITIQSSYRRLMVKKKLQEM-- 2480
I +LK+ A I +Q+ R + LYQ +R A IT+Q+ R + +++ ++M
Sbjct: 800 ITAVALKEAWAAIIIQKHCRGYLV--RSLYQL--IRMATITMQAYSRGFLARRRYRKMLE 855
Query: 2481 QRAAVLIQATFRMYRTYITFQTWKHASILIQQHYRTYRAAKLQRENYIRQWHSAVVIQAA 2540
+ AV++Q R + FQ+ + + IQ YR R K + E+ ++ H V +
Sbjct: 856 EHKAVILQKYARAWLARRRFQSIRRFVLNIQLTYRVQRLQK-KLEDQNKENHGLVEKLTS 914
Query: 2541 YKGMKARQLLR-EKHKASIVIQSTYRMYRQYCFYQKLQWATKIIQEKYRANKKKQKVFQH 2599
++A + + +K +A + +T+R R Y +K + ++EK +K +
Sbjct: 915 LAALRAGDVEKIQKLEAELEKAATHR--RNY--EEKGKRYRDAVEEKLAKLQKHNSELET 970
Query: 2600 NELKKETCVQAGFQDM-----NIKKQ----IQEQHQAAIIIQK 2633
+ + + +Q +++ N+ KQ +Q++ + ++++K
Sbjct: 971 QKEQIQLKLQEKTEELKEKMDNLTKQLFDDVQKEERQRMLLEK 1013
Score = 51.6 bits (122), Expect = 1e-05
Identities = 42/161 (26%), Positives = 78/161 (48%), Gaps = 12/161 (7%)
Query: 1498 FRCFQAQKLYKRRKESILTIQKYYKAYLKGKIERTNYLQKRAAAIQLQAAFRRLKAHNLC 1557
FR Q L K R + + + +++G ++R +L++R AA+ +Q FR +
Sbjct: 740 FRAGQVAYLEKLRLDKLRQSCVMVQKHMRGWLQRKKFLRERRAALIIQQYFRGQQTVRKA 799
Query: 1558 ------RQIRAACVIQSYWRMRQDRVRFLNLKKTIIKFQAHVRKHQQRQKYKKM--KKAA 1609
++ AA +IQ + R R + ++ I QA+ R R++Y+KM + A
Sbjct: 800 ITAVALKEAWAAIIIQKHCRGYLVRSLYQLIRMATITMQAYSRGFLARRRYRKMLEEHKA 859
Query: 1610 VIIQTHFRAYIFAMKVLASYQKTRSAVIVLQSAYRGMQARK 1650
VI+Q + RA++ + +Q R V+ +Q YR + +K
Sbjct: 860 VILQKYARAWLARRR----FQSIRRFVLNIQLTYRVQRLQK 896
Score = 51.2 bits (121), Expect = 2e-05
Identities = 49/192 (25%), Positives = 84/192 (43%), Gaps = 44/192 (22%)
Query: 2122 FIKAMFKMHQSRISYHTMRKAAIVIQVRCRAYYQGKMQREKYLTILKAVKVLQASFRGVR 2181
F +A + ++ +R++ +++Q R G +QR+K+L +A ++Q FRG
Sbjct: 739 FFRAGQVAYLEKLRLDKLRQSCVMVQKHMR----GWLQRKKFLRERRAALIIQQYFRG-- 792
Query: 2182 VRRTLRKMQTA--------ATLIQSNYRRYRQQTYFNKLKKITKTVQQRYWAMKERNIQF 2233
++T+RK TA A +IQ + R Y ++
Sbjct: 793 -QQTVRKAITAVALKEAWAAIIIQKHCRGYLVRSL------------------------- 826
Query: 2234 QRYNKLRHSVIYIQAIFRGKKARRHLKMM--HIAATLIQRRFRTLMMRRRFLSLKKTAIL 2291
Y +R + I +QA RG ARR + M A ++Q+ R + RRRF S+++ +
Sbjct: 827 --YQLIRMATITMQAYSRGFLARRRYRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLN 884
Query: 2292 IQRKYRAHLCTK 2303
IQ YR K
Sbjct: 885 IQLTYRVQRLQK 896
Score = 50.4 bits (119), Expect = 3e-05
Identities = 68/321 (21%), Positives = 131/321 (40%), Gaps = 45/321 (14%)
Query: 1902 LKIQSAFRMAKAQ-KQFRL-----FKTAALVIQQNFRAWTAGRKQCME--------YIEL 1947
+ ++SA ++ K K FR F+++ ++ + A T +C++ +
Sbjct: 604 ITVKSAKQVIKPNSKHFRTTVGSKFRSSLYLLMETLNATTPHYVRCIKPNDEKLPFEFDS 663
Query: 1948 RHAVLVLQSMWKGKTLRRQLQRQHKCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYRAY 2007
+ V L++ +T+R Q I+ Y R + K ++ + K
Sbjct: 664 KRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYGILMTKQELSFSDKKEVCKVVLHR 723
Query: 2008 SIGREQNHLYLKTKAAVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYATYR 2067
I + + KTK Q AY + R+ ++ V +Q R + +KK+ R
Sbjct: 724 LIQDSNQYQFGKTKIFFRAGQVAYLE---KLRLDKLRQSCVMVQKHMRGWLQRKKFLRER 780
Query: 2068 ASAIIIQRWYRGIKITNHQHKEYLNLKKTAIKIQSVYRGIRVRRHIQHMHRAATFIKAMF 2127
+A+IIQ+++RG ++ + TA+ ++ + I +++H
Sbjct: 781 RAALIIQQYFRG--------QQTVRKAITAVALKEAWAAIIIQKHC-------------- 818
Query: 2128 KMHQSRISYHTMRKAAIVIQVRCRAYYQGKMQREKYLTILKAVK--VLQASFRGVRVRRT 2185
+ + R Y +R A I +Q AY +G + R +Y +L+ K +LQ R RR
Sbjct: 819 RGYLVRSLYQLIRMATITMQ----AYSRGFLARRRYRKMLEEHKAVILQKYARAWLARRR 874
Query: 2186 LRKMQTAATLIQSNYRRYRQQ 2206
+ ++ IQ YR R Q
Sbjct: 875 FQSIRRFVLNIQLTYRVQRLQ 895
Score = 49.7 bits (117), Expect = 5e-05
Identities = 46/191 (24%), Positives = 92/191 (48%), Gaps = 28/191 (14%)
Query: 1784 YYHAYKAQVNQRKNFLQVKKAATCLQAAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRVK 1843
++ A + ++ +++++ +Q RG+ R+ ++ AAL IQ FRG
Sbjct: 739 FFRAGQVAYLEKLRLDKLRQSCVMVQKHMRGWLQRKKFLRERRAALIIQQYFRG------ 792
Query: 1844 YQSVLQSIIKIQRWYRAYKTLHDTRTHFLKTKAAVISLQSAYRGWKVRKQIRREHQAALK 1903
Q+V ++I + LK A I +Q RG+ VR + A +
Sbjct: 793 QQTVRKAITAVA----------------LKEAWAAIIIQKHCRGYLVRSLYQLIRMATIT 836
Query: 1904 IQSAFRMAKAQKQFR--LFKTAALVIQQNFRAWTAGRKQCMEYIELRHAVLVLQSMWKGK 1961
+Q+ R A++++R L + A+++Q+ RAW A R+ + +R VL +Q ++ +
Sbjct: 837 MQAYSRGFLARRRYRKMLEEHKAVILQKYARAWLARRR----FQSIRRFVLNIQLTYRVQ 892
Query: 1962 TLRRQLQRQHK 1972
L+++L+ Q+K
Sbjct: 893 RLQKKLEDQNK 903
Score = 48.9 bits (115), Expect = 9e-05
Identities = 40/150 (26%), Positives = 78/150 (52%), Gaps = 11/150 (7%)
Query: 1298 IIQLAVINFLAKQRLRKRVNAALVIQKYWRRVLAQRKLLMLKKEKLEKVQNKAASLIQGY 1357
++Q + +L +++ + AAL+IQ+Y+R RK + K + AA +IQ +
Sbjct: 762 MVQKHMRGWLQRKKFLRERRAALIIQQYFRGQQTVRKAITAVALK----EAWAAIIIQKH 817
Query: 1358 WRRYSTRQRFLKLKYYSIILQSRIRMIIAVTSYKRYL--WATVTIQRHWRAYLRRKQDQQ 1415
R Y R + ++ +I +Q+ R +A Y++ L V +Q++ RA+L R+
Sbjct: 818 CRGYLVRSLYQLIRMATITMQAYSRGFLARRRYRKMLEEHKAVILQKYARAWLARR---- 873
Query: 1416 RYEMLKSSTLIIQSMFRKWK-QRKMQSQVK 1444
R++ ++ L IQ +R + Q+K++ Q K
Sbjct: 874 RFQSIRRFVLNIQLTYRVQRLQKKLEDQNK 903
Score = 47.0 bits (110), Expect = 3e-04
Identities = 54/231 (23%), Positives = 105/231 (45%), Gaps = 23/231 (9%)
Query: 2638 FKIRKHYLHLRATVVSIQRRYRKLTAVRTQAVICIQSYYRGFKVRKDIQNMHRAATLIQS 2697
++ K + RA V+ + R L +R Q+ + +Q + RG+ RK RAA +IQ
Sbjct: 731 YQFGKTKIFFRAGQVAYLEKLR-LDKLR-QSCVMVQKHMRGWLQRKKFLRERRAALIIQQ 788
Query: 2698 FYR----MHRAKVDYETKKT-AIVVIQNYYRLYVRVKTERKNFLAVQKSVRTIQAAFRGM 2752
++R + +A K+ A ++IQ + R Y+ R + ++ + T+QA RG
Sbjct: 789 YFRGQQTVRKAITAVALKEAWAAIIIQKHCRGYL----VRSLYQLIRMATITMQAYSRGF 844
Query: 2753 KVRQKLKNVSEEKMAAIVNQSALCCYRSKTQYEAVQSEGVMIQEWYKASGLAC---SQEA 2809
R++ + + EE A I+ + A + ++ ++++++ + IQ Y+ L Q
Sbjct: 845 LARRRYRKMLEEHKAVILQKYAR-AWLARRRFQSIRRFVLNIQLTYRVQRLQKKLEDQNK 903
Query: 2810 EYHSQSRAAVTIQKAFCRMVTRKLETQKCAALRIQFFLQMAVYRRRFVQQK 2860
E H ++K R + +K L + L+ A RR ++K
Sbjct: 904 ENHG------LVEKLTSLAALRAGDVEKIQKLEAE--LEKAATHRRNYEEK 946
Score = 42.7 bits (99), Expect = 0.006
Identities = 41/175 (23%), Positives = 76/175 (43%), Gaps = 29/175 (16%)
Query: 3062 YIRAREAGKHERIKYIEFKKSTVILQALVRGWLVRKRFLEQRAKIRLLH----------- 3110
+ RA + E+++ + ++S V++Q +RGWL RK+FL +R ++
Sbjct: 739 FFRAGQVAYLEKLRLDKLRQSCVMVQKHMRGWLQRKKFLRERRAALIIQQYFRGQQTVRK 798
Query: 3111 -FTAAAYYHL-NAVRIQRAYKLYLAVKNANKQVNSVICIQRWFRARLQEKRFIQKYHSIK 3168
TA A A+ IQ+ + YL + I +Q + R L +R+ +
Sbjct: 799 AITAVALKEAWAAIIIQKHCRGYLVRSLYQLIRMATITMQAYSRGFLARRRYRKMLE--- 855
Query: 3169 KIEHEGQECLSQRNRAASVIQKAVRHFLLRKKQEKFTSGIIKIQALWRGYSWRKK 3223
EH+ A ++QK R +L R++ + ++ IQ +R +KK
Sbjct: 856 --EHK-----------AVILQKYARAWLARRRFQSIRRFVLNIQLTYRVQRLQKK 897
Score = 38.1 bits (87), Expect = 0.15
Identities = 44/190 (23%), Positives = 88/190 (46%), Gaps = 12/190 (6%)
Query: 1287 KRHQEREKAARIIQLAVINFLAKQRLRKRVNAALVIQKYWRRVLAQRKLLMLKKEKLEKV 1346
K+ +AA IIQ F +Q +RK + A + +++ W ++ Q+ L ++
Sbjct: 774 KKFLRERRAALIIQQY---FRGQQTVRKAITA-VALKEAWAAIIIQKHCRGYLVRSLYQL 829
Query: 1347 QNKAASLIQGYWRRYSTRQRFLKL--KYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHW 1404
A +Q Y R + R+R+ K+ ++ ++ILQ R +A ++ + IQ +
Sbjct: 830 IRMATITMQAYSRGFLARRRYRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQLTY 889
Query: 1405 RAY-LRRKQDQQRYE----MLKSSTLIIQSMFRKWKQRKMQSQVKATVILQRAFREWHLR 1459
R L++K + Q E + K ++L K +K++++++ +R + E R
Sbjct: 890 RVQRLQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKR 949
Query: 1460 -KQAKEENSA 1468
+ A EE A
Sbjct: 950 YRDAVEEKLA 959
Score = 36.2 bits (82), Expect = 0.58
Identities = 25/82 (30%), Positives = 44/82 (53%), Gaps = 5/82 (6%)
Query: 2817 AAVTIQKAFCR--MVTRKLETQKCAALRIQFFLQMAVYRRRF--VQQKRAAITLQHYFRT 2872
AA+ IQK CR +V + + A + +Q + + + RRR+ + ++ A+ LQ Y R
Sbjct: 810 AAIIIQK-HCRGYLVRSLYQLIRMATITMQAYSRGFLARRRYRKMLEEHKAVILQKYARA 868
Query: 2873 WQTRKQFLLYRKAAVVLQNHYR 2894
W R++F R+ + +Q YR
Sbjct: 869 WLARRRFQSIRRFVLNIQLTYR 890
>gi|189083802 myosin VIIA isoform 2 [Homo sapiens]
Length = 2175
Score = 64.3 bits (155), Expect = 2e-09
Identities = 50/182 (27%), Positives = 87/182 (47%), Gaps = 5/182 (2%)
Query: 1655 ILTSVIKIQSYYRAYVSKKEFLSLKNATIKLQSTVKMKQTRKQYLHLRAAALFIQQCYRS 1714
I VI +Q R + + FL LKNA +Q + RK Y +R L +Q +RS
Sbjct: 744 ITDRVILLQKVIRGFKDRSNFLKLKNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRS 803
Query: 1715 KKIAAQKREEYMQMRESCIKLQAFVRGYLVRKQMRLQRKAVISLQSYFRMRKARQYYLKM 1774
+K+ ++Y R+ I+ QA R YLVRK R + AV+++Q+Y R AR+ + ++
Sbjct: 804 RKL----HQQYRLARQRIIQFQARCRAYLVRKAFRHRLWAVLTVQAYARGMIARRLHQRL 859
Query: 1775 YKAIIVIQNYYHAYKAQVNQRKNFLQVKKAATCLQAAYRGYKVRQLIKQQSIAALKIQSA 1834
+ A+ + + + KKA + ++ ++ QL ++ + LK + A
Sbjct: 860 RAEYLWRLEAEKMRLAEEEKLRKEMSAKKAKEEAERKHQ-ERLAQLAREDAERELKEKEA 918
Query: 1835 FR 1836
R
Sbjct: 919 AR 920
Score = 52.4 bits (124), Expect = 8e-06
Identities = 36/129 (27%), Positives = 64/129 (49%), Gaps = 6/129 (4%)
Query: 2231 IQFQRYNKLRHSVIYIQAIFRGKKARRHLKMMHIAATLIQRRFRTLMMRRRFLSLKKTAI 2290
++ +R + VI +Q + RG K R + + AATLIQR +R R+ + ++ +
Sbjct: 736 LEVERDKAITDRVILLQKVIRGFKDRSNFLKLKNAATLIQRHWRGHNCRKNYGLMRLGFL 795
Query: 2291 LIQRKYRAHLCTKHHLQFLQVQNAVIKIQSSYRRWMIRKRMREMHRAATFIQSTFR---M 2347
+Q +R+ K H Q+ + +I+ Q+ R +++RK R A +Q+ R
Sbjct: 796 RLQALHRSR---KLHQQYRLARQRIIQFQARCRAYLVRKAFRHRLWAVLTVQAYARGMIA 852
Query: 2348 HRLHMRYQA 2356
RLH R +A
Sbjct: 853 RRLHQRLRA 861
Score = 51.2 bits (121), Expect = 2e-05
Identities = 39/141 (27%), Positives = 71/141 (50%), Gaps = 12/141 (8%)
Query: 1778 IIVIQNYYHAYKAQVNQRKNFLQVKKAATCLQAAYRGYKVRQLIKQQSIAALKIQSAFRG 1837
+I++Q +K R NFL++K AAT +Q +RG+ R+ + L++Q+ R
Sbjct: 748 VILLQKVIRGFK----DRSNFLKLKNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRS 803
Query: 1838 YNKRVKYQSVLQSIIKIQRWYRAYKTLHDTRTHFLKTKAAVISLQSAYRGW---KVRKQI 1894
+Y+ Q II+ Q RAY R F AV+++Q+ RG ++ +++
Sbjct: 804 RKLHQQYRLARQRIIQFQARCRAYL----VRKAFRHRLWAVLTVQAYARGMIARRLHQRL 859
Query: 1895 RREHQAALKIQSAFRMAKAQK 1915
R E+ L+ + R+A+ +K
Sbjct: 860 RAEYLWRLEAEK-MRLAEEEK 879
Score = 50.4 bits (119), Expect = 3e-05
Identities = 50/206 (24%), Positives = 93/206 (45%), Gaps = 15/206 (7%)
Query: 1528 KIERTNYLQKRAAAIQLQAAFRRLKAH-NLCRQIRAACVIQSYWRMRQDRVRFLNLKKTI 1586
++ER + R I LQ R K N + AA +IQ +WR R + ++
Sbjct: 737 EVERDKAITDRV--ILLQKVIRGFKDRSNFLKLKNAATLIQRHWRGHNCRKNYGLMRLGF 794
Query: 1587 IKFQAHVRKHQQRQKYKKMKKAAVIIQTHFRAYIFAMKVLASYQKTRSAVIVLQSAYRGM 1646
++ QA R + Q+Y+ ++ + Q RAY+ V +++ AV+ +Q+ RGM
Sbjct: 795 LRLQALHRSRKLHQQYRLARQRIIQFQARCRAYL----VRKAFRHRLWAVLTVQAYARGM 850
Query: 1647 QARKMYIHILTSVIKIQSYYRAYVSKKEFLSLKNATIKLQSTVKMKQTRKQYLHLRAAAL 1706
AR+++ + Y ++K L+ + K S K K+ ++ R A L
Sbjct: 851 IARRLHQRLRA------EYLWRLEAEKMRLAEEEKLRKEMSAKKAKEEAERKHQERLAQL 904
Query: 1707 FIQQCYR--SKKIAAQKREEYMQMRE 1730
+ R +K AA++++E ++ E
Sbjct: 905 AREDAERELKEKEAARRKKELLEQME 930
Score = 49.7 bits (117), Expect = 5e-05
Identities = 34/146 (23%), Positives = 68/146 (46%), Gaps = 4/146 (2%)
Query: 1586 IIKFQAHVRKHQQRQKYKKMKKAAVIIQTHFRAYIFAMKVLASYQKTRSAVIVLQSAYRG 1645
+I Q +R + R + K+K AA +IQ H+R + +Y R + LQ+ +R
Sbjct: 748 VILLQKVIRGFKDRSNFLKLKNAATLIQRHWRGH----NCRKNYGLMRLGFLRLQALHRS 803
Query: 1646 MQARKMYIHILTSVIKIQSYYRAYVSKKEFLSLKNATIKLQSTVKMKQTRKQYLHLRAAA 1705
+ + Y +I+ Q+ RAY+ +K F A + +Q+ + R+ + LRA
Sbjct: 804 RKLHQQYRLARQRIIQFQARCRAYLVRKAFRHRLWAVLTVQAYARGMIARRLHQRLRAEY 863
Query: 1706 LFIQQCYRSKKIAAQKREEYMQMRES 1731
L+ + + + +K + M +++
Sbjct: 864 LWRLEAEKMRLAEEEKLRKEMSAKKA 889
Score = 49.3 bits (116), Expect = 7e-05
Identities = 52/197 (26%), Positives = 92/197 (46%), Gaps = 20/197 (10%)
Query: 3021 HEHFLMIKRHRA----ACLIQAHYRGYKGRQVFLRQKSAALIIQKYIRAREAGKHERIKY 3076
H+ L ++R +A L+Q RG+K R FL+ K+AA +IQ++ R K+ +
Sbjct: 732 HDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKLKNAATLIQRHWRGHNCRKNYGLMR 791
Query: 3077 IEFKKSTVILQALVRG-------WLVRKRFLEQRAKIRLLHFTAAAYYHLNAVRIQRAYK 3129
+ F + LQAL R L R+R ++ +A+ R A + L AV +AY
Sbjct: 792 LGFLR----LQALHRSRKLHQQYRLARQRIIQFQARCRAYLVRKAFRHRLWAVLTVQAYA 847
Query: 3130 LYLAVKNANKQVNS-VICIQRWFRARLQEKRFIQKYHSIKKIEHEG----QECLSQRNRA 3184
+ + ++++ + + + RL E+ ++K S KK + E QE L+Q R
Sbjct: 848 RGMIARRLHQRLRAEYLWRLEAEKMRLAEEEKLRKEMSAKKAKEEAERKHQERLAQLARE 907
Query: 3185 ASVIQKAVRHFLLRKKQ 3201
+ + + RKK+
Sbjct: 908 DAERELKEKEAARRKKE 924
Score = 49.3 bits (116), Expect = 7e-05
Identities = 43/166 (25%), Positives = 71/166 (42%), Gaps = 9/166 (5%)
Query: 2071 IIIQRWYRGIKITNHQHKEYLNLKKTAIKIQSVYRGIRVRRHIQHMHRAATFIKAMFKMH 2130
I++Q+ RG K +L LK A IQ +RG R++ M ++A+ +
Sbjct: 749 ILLQKVIRGFK----DRSNFLKLKNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRSR 804
Query: 2131 QSRISYHTMRKAAIVIQVRCRAYYQGKMQREKYLTILKAVKVLQASFRGVRVRRTLRKMQ 2190
+ Y R+ I Q RCRAY K R + L AV +QA RG+ RR ++++
Sbjct: 805 KLHQQYRLARQRIIQFQARCRAYLVRKAFRHR----LWAVLTVQAYARGMIARRLHQRLR 860
Query: 2191 TA-ATLIQSNYRRYRQQTYFNKLKKITKTVQQRYWAMKERNIQFQR 2235
+++ R ++ K K ++ +ER Q R
Sbjct: 861 AEYLWRLEAEKMRLAEEEKLRKEMSAKKAKEEAERKHQERLAQLAR 906
Score = 48.9 bits (115), Expect = 9e-05
Identities = 65/317 (20%), Positives = 132/317 (41%), Gaps = 44/317 (13%)
Query: 1732 CIKLQAFVRGYLVRKQMRLQRKAVISLQSYFRMRKARQYYLKMYKAIIVIQNYY------ 1785
CIK F + L + + +++ + R+R+A Y Y + ++ Y
Sbjct: 635 CIKPNEFKKPMLFDRHLCVRQLRYSGMMETIRIRRAG--YPIRYSFVEFVERYRVLLPGV 692
Query: 1786 -HAYKAQVNQRKNFLQVKKAATCLQAAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRVKY 1844
AYK Q + R ++ +A ++ K + +K L+++ +
Sbjct: 693 KPAYK-QGDLRGTCQRMAEAVLGTHDDWQIGKTKIFLKDHHDMLLEVE----------RD 741
Query: 1845 QSVLQSIIKIQRWYRAYKTLHDTRTHFLKTKAAVISLQSAYRGWKVRKQIRREHQAALKI 1904
+++ +I +Q+ R +K R++FLK K A +Q +RG RK L++
Sbjct: 742 KAITDRVILLQKVIRGFKD----RSNFLKLKNAATLIQRHWRGHNCRKNYGLMRLGFLRL 797
Query: 1905 QSAFRMAKAQKQFRLFKTAALVIQQNFRAWTAGRKQCMEYIELRH---AVLVLQSMWKGK 1961
Q+ R K +Q+RL + + Q RA+ + RH AVL +Q+ +G
Sbjct: 798 QALHRSRKLHQQYRLARQRIIQFQARCRAYLVRK-------AFRHRLWAVLTVQAYARGM 850
Query: 1962 TLRRQLQRQHKCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYRAYSIGREQNHLYLKTK 2021
RR QR +++ Y ++ +K ++ ++ L + + E+ H + +
Sbjct: 851 IARRLHQR-------LRAEYLWRLEAEKMRLAEEEKLRKEMSAKKAKEEAERKH---QER 900
Query: 2022 AAVVTLQSAYRGMKVRK 2038
A + + A R +K ++
Sbjct: 901 LAQLAREDAERELKEKE 917
Score = 47.8 bits (112), Expect = 2e-04
Identities = 44/198 (22%), Positives = 97/198 (48%), Gaps = 8/198 (4%)
Query: 1415 QRYEMLKSSTLIIQSMFRKWKQRKMQSQVK-ATVILQRAFREWHLRKQAKEENSAII-IQ 1472
+R + + +++Q + R +K R ++K A ++QR +R + RK + +Q
Sbjct: 739 ERDKAITDRVILLQKVIRGFKDRSNFLKLKNAATLIQRHWRGHNCRKNYGLMRLGFLRLQ 798
Query: 1473 SWYRMHKELRKYIYIRSCVVIIQKRFRCFQAQKLYKRRKESILTIQKYYKAYLKGKIERT 1532
+ +R K ++Y R ++ Q R R + +K ++ R ++LT+Q AY +G I R
Sbjct: 799 ALHRSRKLHQQYRLARQRIIQFQARCRAYLVRKAFRHRLWAVLTVQ----AYARGMIARR 854
Query: 1533 NYLQKRAAAI-QLQAAFRRL-KAHNLCRQIRAACVIQSYWRMRQDRVRFLNLKKTIIKFQ 1590
+ + RA + +L+A RL + L +++ A + R Q+R+ L + + +
Sbjct: 855 LHQRLRAEYLWRLEAEKMRLAEEEKLRKEMSAKKAKEEAERKHQERLAQLAREDAERELK 914
Query: 1591 AHVRKHQQRQKYKKMKKA 1608
++++ ++M++A
Sbjct: 915 EKEAARRKKELLEQMERA 932
Score = 47.4 bits (111), Expect = 3e-04
Identities = 55/214 (25%), Positives = 96/214 (44%), Gaps = 22/214 (10%)
Query: 2276 LMMRRRFLSLKKTAILIQRKYRAHLCTKHHLQFLQVQNAVIKIQSSYRRWMIRKRMREMH 2335
L+ R ++ IL+Q+ R K FL+++NA IQ +R RK M
Sbjct: 735 LLEVERDKAITDRVILLQKVIRGF---KDRSNFLKLKNAATLIQRHWRGHNCRKNYGLMR 791
Query: 2336 RAATFIQSTFRMHRLHMRYQALKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAF 2395
+Q+ R +LH +Y+ +Q + Q+QA A L R+ + + + + +QA
Sbjct: 792 LGFLRLQALHRSRKLHQQYRLARQRII----QFQARCRAYLVRKAFRHRLWAVLTVQAYA 847
Query: 2396 RGMKTRRHLKSMHSSATLIQSRFRSLLVR----RRFISLKKATIFVQRKYRATIC--AKH 2449
RGM RR + + + + L R+ +S KKA +RK++ + A+
Sbjct: 848 RGMIARRLHQRLRAEYLWRLEAEKMRLAEEEKLRKEMSAKKAKEEAERKHQERLAQLARE 907
Query: 2450 KLYQFLHLRKAAITIQSSYRRLMVKKKLQEMQRA 2483
+ L ++AA RR K+ L++M+RA
Sbjct: 908 DAERELKEKEAA-------RR--KKELLEQMERA 932
Score = 45.4 bits (106), Expect = 0.001
Identities = 35/139 (25%), Positives = 58/139 (41%), Gaps = 15/139 (10%)
Query: 2024 VVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKIT 2083
V+ LQ RG K R AA IQ +R + +K Y R + +Q +R K+
Sbjct: 748 VILLQKVIRGFKDRSNFLKLKNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKL- 806
Query: 2084 NHQHKEYLNLKKTAIKIQSVYRGIRVRRHIQHMHRAATFIKAMFKMHQSRISYHTMRKAA 2143
H++Y ++ I+ Q+ R VR+ +H A ++A + A
Sbjct: 807 ---HQQYRLARQRIIQFQARCRAYLVRKAFRHRLWAVLTVQA-----------YARGMIA 852
Query: 2144 IVIQVRCRAYYQGKMQREK 2162
+ R RA Y +++ EK
Sbjct: 853 RRLHQRLRAEYLWRLEAEK 871
Score = 43.9 bits (102), Expect = 0.003
Identities = 48/233 (20%), Positives = 97/233 (41%), Gaps = 32/233 (13%)
Query: 2157 KMQREKYLTILKAVKVLQASFRGVRVRRTLRKMQTAATLIQSNYRRYRQQTYFNKLKKIT 2216
+++R+K +T V +LQ RG + R K++ AATLIQ ++R + +
Sbjct: 737 EVERDKAIT--DRVILLQKVIRGFKDRSNFLKLKNAATLIQRHWRGHNCR---------- 784
Query: 2217 KTVQQRYWAMKERNIQFQRYNKLRHSVIYIQAIFRGKKARRHLKMMHIAATLIQRRFRTL 2276
+ Y +R + +QA+ R +K + ++ Q R R
Sbjct: 785 -----------------KNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQARCRAY 827
Query: 2277 MMRRRFLSLKKTAILIQRKYRAHLCTKHHLQFLQVQNAVIKIQSSYRRWMIRKRMREMHR 2336
++R+ F + +Q R + + H Q L+ + + ++++ R +++R+
Sbjct: 828 LVRKAFRHRLWAVLTVQAYARGMIARRLH-QRLRAE-YLWRLEAEKMRLAEEEKLRKEMS 885
Query: 2337 AATFIQSTFRMHRLHMRYQALKQASVVIQQQYQANRAAKLQRQHYLRQRHSAV 2389
A + R H+ + A + A ++++ A R +L Q R RH V
Sbjct: 886 AKKAKEEAERKHQERLAQLAREDAERELKEKEAARRKKELLEQ-MERARHEPV 937
Score = 43.5 bits (101), Expect = 0.004
Identities = 48/200 (24%), Positives = 84/200 (42%), Gaps = 34/200 (17%)
Query: 2884 KAAVVLQNHYRAFLSAKHQRQVYLQIRSSVIIIQARSKGFIQKRKFQEIKNSTIKIQAMW 2943
K + L++H+ L + + I VI++Q +GF + F ++KN+ IQ W
Sbjct: 723 KTKIFLKDHHDMLLEVERDKA----ITDRVILLQKVIRGFKDRSNFLKLKNAATLIQRHW 778
Query: 2944 RRYRAKK-YLCKVKAACKIQAWYRCWRAHKEYLAILKAVKIIQGCFYTKLERTRFLNVRA 3002
R + +K Y ++QA +R + H++Y +L R R +
Sbjct: 779 RGHNCRKNYGLMRLGFLRLQALHRSRKLHQQY----------------RLARQRIIQ--- 819
Query: 3003 SAIIIQRKWRAILPAKIAHEHFLMIKRHRAACLIQAHYRGYKGRQVFLRQKSAALIIQKY 3062
Q + RA L K A H L A +QA+ RG R++ R ++ L +
Sbjct: 820 ----FQARCRAYLVRK-AFRHRLW-----AVLTVQAYARGMIARRLHQRLRAEYLWRLEA 869
Query: 3063 IRAREAGKHERIKYIEFKKS 3082
+ R A + + K + KK+
Sbjct: 870 EKMRLAEEEKLRKEMSAKKA 889
Score = 42.4 bits (98), Expect = 0.008
Identities = 27/90 (30%), Positives = 44/90 (48%), Gaps = 5/90 (5%)
Query: 2666 TQAVICIQSYYRGFKVRKDIQNMHRAATLIQSFYRMHRAKVDYETKKTAIVVIQNYYR-- 2723
T VI +Q RGFK R + + AATLIQ +R H + +Y + + +Q +R
Sbjct: 745 TDRVILLQKVIRGFKDRSNFLKLKNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRSR 804
Query: 2724 -LYVRVKTERKNFLAVQKSVRT--IQAAFR 2750
L+ + + R+ + Q R ++ AFR
Sbjct: 805 KLHQQYRLARQRIIQFQARCRAYLVRKAFR 834
Score = 40.8 bits (94), Expect = 0.024
Identities = 28/118 (23%), Positives = 56/118 (47%), Gaps = 4/118 (3%)
Query: 1951 VLVLQSMWKGKTLRRQLQRQHKCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYRAYSIG 2010
V++LQ + +G R + A +IQ ++R H +K + +M+ L +Q +R+
Sbjct: 748 VILLQKVIRGFKDRSNFLKLKNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRS---- 803
Query: 2011 REQNHLYLKTKAAVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYATYRA 2068
R+ + Y + ++ Q+ R VRK + A +T+Q+ R ++ + RA
Sbjct: 804 RKLHQQYRLARQRIIQFQARCRAYLVRKAFRHRLWAVLTVQAYARGMIARRLHQRLRA 861
Score = 40.4 bits (93), Expect = 0.031
Identities = 36/180 (20%), Positives = 73/180 (40%), Gaps = 22/180 (12%)
Query: 2459 KAAITIQSSYRRLMVKKKLQEMQRAAVLIQATFRMYRTYITFQTWKHASILIQQHYRTYR 2518
K I ++ + L+ ++ + + +L+Q R ++ F K+A+ LIQ+H+R +
Sbjct: 723 KTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKLKNAATLIQRHWRGHN 782
Query: 2519 AAKLQRENYIRQWHSAVVIQAAYKGMKARQLLREKHKASIVIQSTYRMYRQYCFYQKLQW 2578
R+NY + +QA ++ K Q R + I Q+ R Y ++ W
Sbjct: 783 C----RKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQARCRAYLVRKAFRHRLW 838
Query: 2579 ATKIIQE------------------KYRANKKKQKVFQHNELKKETCVQAGFQDMNIKKQ 2620
A +Q +R +K ++ + +L+KE + ++ K Q
Sbjct: 839 AVLTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRLAEEEKLRKEMSAKKAKEEAERKHQ 898
Score = 40.4 bits (93), Expect = 0.031
Identities = 34/128 (26%), Positives = 52/128 (40%), Gaps = 22/128 (17%)
Query: 2629 IIIQKHCKAFKIRKHYLHLRATVVSIQRRYRKLTAVRTQAVICIQSYYRGFKVRKDIQNM 2688
I++QK + FK R ++L L+ IQR ++RG RK+ M
Sbjct: 749 ILLQKVIRGFKDRSNFLKLKNAATLIQR------------------HWRGHNCRKNYGLM 790
Query: 2689 HRAATLIQSFYRMHRAKVDYETKKTAIVVIQNYYRLYVRVKTERKNFLAVQKSVRTIQAA 2748
+Q+ +R + Y + I+ Q R Y+ K R A V T+QA
Sbjct: 791 RLGFLRLQALHRSRKLHQQYRLARQRIIQFQARCRAYLVRKAFRHRLWA----VLTVQAY 846
Query: 2749 FRGMKVRQ 2756
RGM R+
Sbjct: 847 ARGMIARR 854
Score = 39.3 bits (90), Expect = 0.069
Identities = 51/213 (23%), Positives = 85/213 (39%), Gaps = 47/213 (22%)
Query: 1277 WRKYKLKTDLKRHQEREKAARIIQLAVINFLAKQRLRKRVNAALVIQKYWRRVLAQRKLL 1336
W+ K K LK H + L +R + + +++QK R + L
Sbjct: 719 WQIGKTKIFLKDHHDM-------------LLEVERDKAITDRVILLQKVIRGFKDRSNFL 765
Query: 1337 MLKKEKLEKVQNKAASLIQGYWRRYSTRQR-------FLKL----------------KYY 1373
LK AA+LIQ +WR ++ R+ FL+L +
Sbjct: 766 KLKN---------AATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQR 816
Query: 1374 SIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQ-RYEMLKSSTLIIQSMFR 1432
I Q+R R + +++ LWA +T+Q + R + R+ Q+ R E L +
Sbjct: 817 IIQFQARCRAYLVRKAFRHRLWAVLTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRLAE 876
Query: 1433 KWKQRKMQSQVKATVILQRAFREWHLRKQAKEE 1465
+ K RK S KA +R +E L + A+E+
Sbjct: 877 EEKLRKEMSAKKAKEEAERKHQE-RLAQLARED 908
Score = 38.9 bits (89), Expect = 0.090
Identities = 32/145 (22%), Positives = 63/145 (43%), Gaps = 8/145 (5%)
Query: 1972 KCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYRAYSIGREQNHLYLKTKAAVVTLQSAY 2031
K I ++ ++ M ++ ++ K + +L+QK R + + +LK K A +Q +
Sbjct: 723 KTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGF----KDRSNFLKLKNAATLIQRHW 778
Query: 2032 RGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKITNHQHKEYL 2091
RG RK + +Q+ +R+ K ++Y R I Q R + K +
Sbjct: 779 RGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQARCRAYLV----RKAFR 834
Query: 2092 NLKKTAIKIQSVYRGIRVRRHIQHM 2116
+ + +Q+ RG+ RR Q +
Sbjct: 835 HRLWAVLTVQAYARGMIARRLHQRL 859
Score = 37.4 bits (85), Expect = 0.26
Identities = 29/115 (25%), Positives = 55/115 (47%), Gaps = 16/115 (13%)
Query: 2558 IVIQSTYRMYRQYCFYQKLQWATKIIQEKYRANKKKQKVFQHNELKKETCVQAGF---QD 2614
I++Q R ++ + KL+ A +IQ +R HN K ++ GF Q
Sbjct: 749 ILLQKVIRGFKDRSNFLKLKNAATLIQRHWRG---------HNCRKNYGLMRLGFLRLQA 799
Query: 2615 MNIKKQIQEQHQAA----IIIQKHCKAFKIRKHYLHLRATVVSIQRRYRKLTAVR 2665
++ +++ +Q++ A I Q C+A+ +RK + H V+++Q R + A R
Sbjct: 800 LHRSRKLHQQYRLARQRIIQFQARCRAYLVRKAFRHRLWAVLTVQAYARGMIARR 854
Score = 35.8 bits (81), Expect = 0.76
Identities = 34/138 (24%), Positives = 63/138 (45%), Gaps = 13/138 (9%)
Query: 3124 IQRAYKLYLAVKNANKQVNSVICIQRWFRARL---------QEKRFIQKYHSIKKIEHEG 3174
++R L VK A KQ + QR A L + K F++ +H + +E E
Sbjct: 682 VERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQIGKTKIFLKDHHDML-LEVER 740
Query: 3175 QECLSQRNRAASVIQKAVRHFLLRKKQEKFTSGIIKIQALWRGYSWRKKNDCTKIKAIRL 3234
+ ++ R ++QK +R F R K + IQ WRG++ RK ++ +RL
Sbjct: 741 DKAITDR---VILLQKVIRGFKDRSNFLKLKNAATLIQRHWRGHNCRKNYGLMRLGFLRL 797
Query: 3235 SLQVVNREIREENKLYKR 3252
+R++ ++ +L ++
Sbjct: 798 QALHRSRKLHQQYRLARQ 815
Score = 35.8 bits (81), Expect = 0.76
Identities = 40/176 (22%), Positives = 70/176 (39%), Gaps = 28/176 (15%)
Query: 2454 FLHLRKAAITIQSSYRRLMVKKKLQEMQRAAVLIQATFRMYRTYITFQTWKHASILIQQH 2513
FL L+ AA IQ +R +K M+ + +QA R + + ++ + I Q
Sbjct: 764 FLKLKNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQAR 823
Query: 2514 YRTYRAAKLQRENYIRQWHSAVVIQAAYKGMKARQL------------------------ 2549
R Y K R R W + + +QA +GM AR+L
Sbjct: 824 CRAYLVRKAFRH---RLW-AVLTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRLAEEEK 879
Query: 2550 LREKHKASIVIQSTYRMYRQYCFYQKLQWATKIIQEKYRANKKKQKVFQHNELKKE 2605
LR++ A + R +++ + A + ++EK A +KK+ + Q + E
Sbjct: 880 LRKEMSAKKAKEEAERKHQERLAQLAREDAERELKEKEAARRKKELLEQMERARHE 935
>gi|189083800 myosin VIIA isoform 3 [Homo sapiens]
Length = 1204
Score = 64.3 bits (155), Expect = 2e-09
Identities = 50/182 (27%), Positives = 87/182 (47%), Gaps = 5/182 (2%)
Query: 1655 ILTSVIKIQSYYRAYVSKKEFLSLKNATIKLQSTVKMKQTRKQYLHLRAAALFIQQCYRS 1714
I VI +Q R + + FL LKNA +Q + RK Y +R L +Q +RS
Sbjct: 744 ITDRVILLQKVIRGFKDRSNFLKLKNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRS 803
Query: 1715 KKIAAQKREEYMQMRESCIKLQAFVRGYLVRKQMRLQRKAVISLQSYFRMRKARQYYLKM 1774
+K+ ++Y R+ I+ QA R YLVRK R + AV+++Q+Y R AR+ + ++
Sbjct: 804 RKL----HQQYRLARQRIIQFQARCRAYLVRKAFRHRLWAVLTVQAYARGMIARRLHQRL 859
Query: 1775 YKAIIVIQNYYHAYKAQVNQRKNFLQVKKAATCLQAAYRGYKVRQLIKQQSIAALKIQSA 1834
+ A+ + + + KKA + ++ ++ QL ++ + LK + A
Sbjct: 860 RAEYLWRLEAEKMRLAEEEKLRKEMSAKKAKEEAERKHQ-ERLAQLAREDAERELKEKEA 918
Query: 1835 FR 1836
R
Sbjct: 919 AR 920
Score = 52.4 bits (124), Expect = 8e-06
Identities = 36/129 (27%), Positives = 64/129 (49%), Gaps = 6/129 (4%)
Query: 2231 IQFQRYNKLRHSVIYIQAIFRGKKARRHLKMMHIAATLIQRRFRTLMMRRRFLSLKKTAI 2290
++ +R + VI +Q + RG K R + + AATLIQR +R R+ + ++ +
Sbjct: 736 LEVERDKAITDRVILLQKVIRGFKDRSNFLKLKNAATLIQRHWRGHNCRKNYGLMRLGFL 795
Query: 2291 LIQRKYRAHLCTKHHLQFLQVQNAVIKIQSSYRRWMIRKRMREMHRAATFIQSTFR---M 2347
+Q +R+ K H Q+ + +I+ Q+ R +++RK R A +Q+ R
Sbjct: 796 RLQALHRSR---KLHQQYRLARQRIIQFQARCRAYLVRKAFRHRLWAVLTVQAYARGMIA 852
Query: 2348 HRLHMRYQA 2356
RLH R +A
Sbjct: 853 RRLHQRLRA 861
Score = 51.2 bits (121), Expect = 2e-05
Identities = 39/141 (27%), Positives = 71/141 (50%), Gaps = 12/141 (8%)
Query: 1778 IIVIQNYYHAYKAQVNQRKNFLQVKKAATCLQAAYRGYKVRQLIKQQSIAALKIQSAFRG 1837
+I++Q +K R NFL++K AAT +Q +RG+ R+ + L++Q+ R
Sbjct: 748 VILLQKVIRGFK----DRSNFLKLKNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRS 803
Query: 1838 YNKRVKYQSVLQSIIKIQRWYRAYKTLHDTRTHFLKTKAAVISLQSAYRGW---KVRKQI 1894
+Y+ Q II+ Q RAY R F AV+++Q+ RG ++ +++
Sbjct: 804 RKLHQQYRLARQRIIQFQARCRAYL----VRKAFRHRLWAVLTVQAYARGMIARRLHQRL 859
Query: 1895 RREHQAALKIQSAFRMAKAQK 1915
R E+ L+ + R+A+ +K
Sbjct: 860 RAEYLWRLEAEK-MRLAEEEK 879
Score = 50.4 bits (119), Expect = 3e-05
Identities = 50/206 (24%), Positives = 93/206 (45%), Gaps = 15/206 (7%)
Query: 1528 KIERTNYLQKRAAAIQLQAAFRRLKAH-NLCRQIRAACVIQSYWRMRQDRVRFLNLKKTI 1586
++ER + R I LQ R K N + AA +IQ +WR R + ++
Sbjct: 737 EVERDKAITDRV--ILLQKVIRGFKDRSNFLKLKNAATLIQRHWRGHNCRKNYGLMRLGF 794
Query: 1587 IKFQAHVRKHQQRQKYKKMKKAAVIIQTHFRAYIFAMKVLASYQKTRSAVIVLQSAYRGM 1646
++ QA R + Q+Y+ ++ + Q RAY+ V +++ AV+ +Q+ RGM
Sbjct: 795 LRLQALHRSRKLHQQYRLARQRIIQFQARCRAYL----VRKAFRHRLWAVLTVQAYARGM 850
Query: 1647 QARKMYIHILTSVIKIQSYYRAYVSKKEFLSLKNATIKLQSTVKMKQTRKQYLHLRAAAL 1706
AR+++ + Y ++K L+ + K S K K+ ++ R A L
Sbjct: 851 IARRLHQRLRA------EYLWRLEAEKMRLAEEEKLRKEMSAKKAKEEAERKHQERLAQL 904
Query: 1707 FIQQCYR--SKKIAAQKREEYMQMRE 1730
+ R +K AA++++E ++ E
Sbjct: 905 AREDAERELKEKEAARRKKELLEQME 930
Score = 49.7 bits (117), Expect = 5e-05
Identities = 34/146 (23%), Positives = 68/146 (46%), Gaps = 4/146 (2%)
Query: 1586 IIKFQAHVRKHQQRQKYKKMKKAAVIIQTHFRAYIFAMKVLASYQKTRSAVIVLQSAYRG 1645
+I Q +R + R + K+K AA +IQ H+R + +Y R + LQ+ +R
Sbjct: 748 VILLQKVIRGFKDRSNFLKLKNAATLIQRHWRGH----NCRKNYGLMRLGFLRLQALHRS 803
Query: 1646 MQARKMYIHILTSVIKIQSYYRAYVSKKEFLSLKNATIKLQSTVKMKQTRKQYLHLRAAA 1705
+ + Y +I+ Q+ RAY+ +K F A + +Q+ + R+ + LRA
Sbjct: 804 RKLHQQYRLARQRIIQFQARCRAYLVRKAFRHRLWAVLTVQAYARGMIARRLHQRLRAEY 863
Query: 1706 LFIQQCYRSKKIAAQKREEYMQMRES 1731
L+ + + + +K + M +++
Sbjct: 864 LWRLEAEKMRLAEEEKLRKEMSAKKA 889
Score = 49.3 bits (116), Expect = 7e-05
Identities = 52/197 (26%), Positives = 92/197 (46%), Gaps = 20/197 (10%)
Query: 3021 HEHFLMIKRHRA----ACLIQAHYRGYKGRQVFLRQKSAALIIQKYIRAREAGKHERIKY 3076
H+ L ++R +A L+Q RG+K R FL+ K+AA +IQ++ R K+ +
Sbjct: 732 HDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKLKNAATLIQRHWRGHNCRKNYGLMR 791
Query: 3077 IEFKKSTVILQALVRG-------WLVRKRFLEQRAKIRLLHFTAAAYYHLNAVRIQRAYK 3129
+ F + LQAL R L R+R ++ +A+ R A + L AV +AY
Sbjct: 792 LGFLR----LQALHRSRKLHQQYRLARQRIIQFQARCRAYLVRKAFRHRLWAVLTVQAYA 847
Query: 3130 LYLAVKNANKQVNS-VICIQRWFRARLQEKRFIQKYHSIKKIEHEG----QECLSQRNRA 3184
+ + ++++ + + + RL E+ ++K S KK + E QE L+Q R
Sbjct: 848 RGMIARRLHQRLRAEYLWRLEAEKMRLAEEEKLRKEMSAKKAKEEAERKHQERLAQLARE 907
Query: 3185 ASVIQKAVRHFLLRKKQ 3201
+ + + RKK+
Sbjct: 908 DAERELKEKEAARRKKE 924
Score = 49.3 bits (116), Expect = 7e-05
Identities = 43/166 (25%), Positives = 71/166 (42%), Gaps = 9/166 (5%)
Query: 2071 IIIQRWYRGIKITNHQHKEYLNLKKTAIKIQSVYRGIRVRRHIQHMHRAATFIKAMFKMH 2130
I++Q+ RG K +L LK A IQ +RG R++ M ++A+ +
Sbjct: 749 ILLQKVIRGFK----DRSNFLKLKNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRSR 804
Query: 2131 QSRISYHTMRKAAIVIQVRCRAYYQGKMQREKYLTILKAVKVLQASFRGVRVRRTLRKMQ 2190
+ Y R+ I Q RCRAY K R + L AV +QA RG+ RR ++++
Sbjct: 805 KLHQQYRLARQRIIQFQARCRAYLVRKAFRHR----LWAVLTVQAYARGMIARRLHQRLR 860
Query: 2191 TA-ATLIQSNYRRYRQQTYFNKLKKITKTVQQRYWAMKERNIQFQR 2235
+++ R ++ K K ++ +ER Q R
Sbjct: 861 AEYLWRLEAEKMRLAEEEKLRKEMSAKKAKEEAERKHQERLAQLAR 906
Score = 48.9 bits (115), Expect = 9e-05
Identities = 65/317 (20%), Positives = 132/317 (41%), Gaps = 44/317 (13%)
Query: 1732 CIKLQAFVRGYLVRKQMRLQRKAVISLQSYFRMRKARQYYLKMYKAIIVIQNYY------ 1785
CIK F + L + + +++ + R+R+A Y Y + ++ Y
Sbjct: 635 CIKPNEFKKPMLFDRHLCVRQLRYSGMMETIRIRRAG--YPIRYSFVEFVERYRVLLPGV 692
Query: 1786 -HAYKAQVNQRKNFLQVKKAATCLQAAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRVKY 1844
AYK Q + R ++ +A ++ K + +K L+++ +
Sbjct: 693 KPAYK-QGDLRGTCQRMAEAVLGTHDDWQIGKTKIFLKDHHDMLLEVE----------RD 741
Query: 1845 QSVLQSIIKIQRWYRAYKTLHDTRTHFLKTKAAVISLQSAYRGWKVRKQIRREHQAALKI 1904
+++ +I +Q+ R +K R++FLK K A +Q +RG RK L++
Sbjct: 742 KAITDRVILLQKVIRGFKD----RSNFLKLKNAATLIQRHWRGHNCRKNYGLMRLGFLRL 797
Query: 1905 QSAFRMAKAQKQFRLFKTAALVIQQNFRAWTAGRKQCMEYIELRH---AVLVLQSMWKGK 1961
Q+ R K +Q+RL + + Q RA+ + RH AVL +Q+ +G
Sbjct: 798 QALHRSRKLHQQYRLARQRIIQFQARCRAYLVRK-------AFRHRLWAVLTVQAYARGM 850
Query: 1962 TLRRQLQRQHKCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYRAYSIGREQNHLYLKTK 2021
RR QR +++ Y ++ +K ++ ++ L + + E+ H + +
Sbjct: 851 IARRLHQR-------LRAEYLWRLEAEKMRLAEEEKLRKEMSAKKAKEEAERKH---QER 900
Query: 2022 AAVVTLQSAYRGMKVRK 2038
A + + A R +K ++
Sbjct: 901 LAQLAREDAERELKEKE 917
Score = 47.8 bits (112), Expect = 2e-04
Identities = 44/198 (22%), Positives = 97/198 (48%), Gaps = 8/198 (4%)
Query: 1415 QRYEMLKSSTLIIQSMFRKWKQRKMQSQVK-ATVILQRAFREWHLRKQAKEENSAII-IQ 1472
+R + + +++Q + R +K R ++K A ++QR +R + RK + +Q
Sbjct: 739 ERDKAITDRVILLQKVIRGFKDRSNFLKLKNAATLIQRHWRGHNCRKNYGLMRLGFLRLQ 798
Query: 1473 SWYRMHKELRKYIYIRSCVVIIQKRFRCFQAQKLYKRRKESILTIQKYYKAYLKGKIERT 1532
+ +R K ++Y R ++ Q R R + +K ++ R ++LT+Q AY +G I R
Sbjct: 799 ALHRSRKLHQQYRLARQRIIQFQARCRAYLVRKAFRHRLWAVLTVQ----AYARGMIARR 854
Query: 1533 NYLQKRAAAI-QLQAAFRRL-KAHNLCRQIRAACVIQSYWRMRQDRVRFLNLKKTIIKFQ 1590
+ + RA + +L+A RL + L +++ A + R Q+R+ L + + +
Sbjct: 855 LHQRLRAEYLWRLEAEKMRLAEEEKLRKEMSAKKAKEEAERKHQERLAQLAREDAERELK 914
Query: 1591 AHVRKHQQRQKYKKMKKA 1608
++++ ++M++A
Sbjct: 915 EKEAARRKKELLEQMERA 932
Score = 47.4 bits (111), Expect = 3e-04
Identities = 55/214 (25%), Positives = 96/214 (44%), Gaps = 22/214 (10%)
Query: 2276 LMMRRRFLSLKKTAILIQRKYRAHLCTKHHLQFLQVQNAVIKIQSSYRRWMIRKRMREMH 2335
L+ R ++ IL+Q+ R K FL+++NA IQ +R RK M
Sbjct: 735 LLEVERDKAITDRVILLQKVIRGF---KDRSNFLKLKNAATLIQRHWRGHNCRKNYGLMR 791
Query: 2336 RAATFIQSTFRMHRLHMRYQALKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAF 2395
+Q+ R +LH +Y+ +Q + Q+QA A L R+ + + + + +QA
Sbjct: 792 LGFLRLQALHRSRKLHQQYRLARQRII----QFQARCRAYLVRKAFRHRLWAVLTVQAYA 847
Query: 2396 RGMKTRRHLKSMHSSATLIQSRFRSLLVR----RRFISLKKATIFVQRKYRATIC--AKH 2449
RGM RR + + + + L R+ +S KKA +RK++ + A+
Sbjct: 848 RGMIARRLHQRLRAEYLWRLEAEKMRLAEEEKLRKEMSAKKAKEEAERKHQERLAQLARE 907
Query: 2450 KLYQFLHLRKAAITIQSSYRRLMVKKKLQEMQRA 2483
+ L ++AA RR K+ L++M+RA
Sbjct: 908 DAERELKEKEAA-------RR--KKELLEQMERA 932
Score = 45.4 bits (106), Expect = 0.001
Identities = 35/139 (25%), Positives = 58/139 (41%), Gaps = 15/139 (10%)
Query: 2024 VVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKIT 2083
V+ LQ RG K R AA IQ +R + +K Y R + +Q +R K+
Sbjct: 748 VILLQKVIRGFKDRSNFLKLKNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKL- 806
Query: 2084 NHQHKEYLNLKKTAIKIQSVYRGIRVRRHIQHMHRAATFIKAMFKMHQSRISYHTMRKAA 2143
H++Y ++ I+ Q+ R VR+ +H A ++A + A
Sbjct: 807 ---HQQYRLARQRIIQFQARCRAYLVRKAFRHRLWAVLTVQA-----------YARGMIA 852
Query: 2144 IVIQVRCRAYYQGKMQREK 2162
+ R RA Y +++ EK
Sbjct: 853 RRLHQRLRAEYLWRLEAEK 871
Score = 43.9 bits (102), Expect = 0.003
Identities = 48/233 (20%), Positives = 97/233 (41%), Gaps = 32/233 (13%)
Query: 2157 KMQREKYLTILKAVKVLQASFRGVRVRRTLRKMQTAATLIQSNYRRYRQQTYFNKLKKIT 2216
+++R+K +T V +LQ RG + R K++ AATLIQ ++R + +
Sbjct: 737 EVERDKAIT--DRVILLQKVIRGFKDRSNFLKLKNAATLIQRHWRGHNCR---------- 784
Query: 2217 KTVQQRYWAMKERNIQFQRYNKLRHSVIYIQAIFRGKKARRHLKMMHIAATLIQRRFRTL 2276
+ Y +R + +QA+ R +K + ++ Q R R
Sbjct: 785 -----------------KNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQARCRAY 827
Query: 2277 MMRRRFLSLKKTAILIQRKYRAHLCTKHHLQFLQVQNAVIKIQSSYRRWMIRKRMREMHR 2336
++R+ F + +Q R + + H Q L+ + + ++++ R +++R+
Sbjct: 828 LVRKAFRHRLWAVLTVQAYARGMIARRLH-QRLRAE-YLWRLEAEKMRLAEEEKLRKEMS 885
Query: 2337 AATFIQSTFRMHRLHMRYQALKQASVVIQQQYQANRAAKLQRQHYLRQRHSAV 2389
A + R H+ + A + A ++++ A R +L Q R RH V
Sbjct: 886 AKKAKEEAERKHQERLAQLAREDAERELKEKEAARRKKELLEQ-MERARHEPV 937
Score = 43.5 bits (101), Expect = 0.004
Identities = 48/200 (24%), Positives = 84/200 (42%), Gaps = 34/200 (17%)
Query: 2884 KAAVVLQNHYRAFLSAKHQRQVYLQIRSSVIIIQARSKGFIQKRKFQEIKNSTIKIQAMW 2943
K + L++H+ L + + I VI++Q +GF + F ++KN+ IQ W
Sbjct: 723 KTKIFLKDHHDMLLEVERDKA----ITDRVILLQKVIRGFKDRSNFLKLKNAATLIQRHW 778
Query: 2944 RRYRAKK-YLCKVKAACKIQAWYRCWRAHKEYLAILKAVKIIQGCFYTKLERTRFLNVRA 3002
R + +K Y ++QA +R + H++Y +L R R +
Sbjct: 779 RGHNCRKNYGLMRLGFLRLQALHRSRKLHQQY----------------RLARQRIIQ--- 819
Query: 3003 SAIIIQRKWRAILPAKIAHEHFLMIKRHRAACLIQAHYRGYKGRQVFLRQKSAALIIQKY 3062
Q + RA L K A H L A +QA+ RG R++ R ++ L +
Sbjct: 820 ----FQARCRAYLVRK-AFRHRLW-----AVLTVQAYARGMIARRLHQRLRAEYLWRLEA 869
Query: 3063 IRAREAGKHERIKYIEFKKS 3082
+ R A + + K + KK+
Sbjct: 870 EKMRLAEEEKLRKEMSAKKA 889
Score = 42.4 bits (98), Expect = 0.008
Identities = 27/90 (30%), Positives = 44/90 (48%), Gaps = 5/90 (5%)
Query: 2666 TQAVICIQSYYRGFKVRKDIQNMHRAATLIQSFYRMHRAKVDYETKKTAIVVIQNYYR-- 2723
T VI +Q RGFK R + + AATLIQ +R H + +Y + + +Q +R
Sbjct: 745 TDRVILLQKVIRGFKDRSNFLKLKNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRSR 804
Query: 2724 -LYVRVKTERKNFLAVQKSVRT--IQAAFR 2750
L+ + + R+ + Q R ++ AFR
Sbjct: 805 KLHQQYRLARQRIIQFQARCRAYLVRKAFR 834
Score = 40.8 bits (94), Expect = 0.024
Identities = 28/118 (23%), Positives = 56/118 (47%), Gaps = 4/118 (3%)
Query: 1951 VLVLQSMWKGKTLRRQLQRQHKCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYRAYSIG 2010
V++LQ + +G R + A +IQ ++R H +K + +M+ L +Q +R+
Sbjct: 748 VILLQKVIRGFKDRSNFLKLKNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRS---- 803
Query: 2011 REQNHLYLKTKAAVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYATYRA 2068
R+ + Y + ++ Q+ R VRK + A +T+Q+ R ++ + RA
Sbjct: 804 RKLHQQYRLARQRIIQFQARCRAYLVRKAFRHRLWAVLTVQAYARGMIARRLHQRLRA 861
Score = 40.4 bits (93), Expect = 0.031
Identities = 36/180 (20%), Positives = 73/180 (40%), Gaps = 22/180 (12%)
Query: 2459 KAAITIQSSYRRLMVKKKLQEMQRAAVLIQATFRMYRTYITFQTWKHASILIQQHYRTYR 2518
K I ++ + L+ ++ + + +L+Q R ++ F K+A+ LIQ+H+R +
Sbjct: 723 KTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKLKNAATLIQRHWRGHN 782
Query: 2519 AAKLQRENYIRQWHSAVVIQAAYKGMKARQLLREKHKASIVIQSTYRMYRQYCFYQKLQW 2578
R+NY + +QA ++ K Q R + I Q+ R Y ++ W
Sbjct: 783 C----RKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQARCRAYLVRKAFRHRLW 838
Query: 2579 ATKIIQE------------------KYRANKKKQKVFQHNELKKETCVQAGFQDMNIKKQ 2620
A +Q +R +K ++ + +L+KE + ++ K Q
Sbjct: 839 AVLTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRLAEEEKLRKEMSAKKAKEEAERKHQ 898
Score = 40.4 bits (93), Expect = 0.031
Identities = 34/128 (26%), Positives = 52/128 (40%), Gaps = 22/128 (17%)
Query: 2629 IIIQKHCKAFKIRKHYLHLRATVVSIQRRYRKLTAVRTQAVICIQSYYRGFKVRKDIQNM 2688
I++QK + FK R ++L L+ IQR ++RG RK+ M
Sbjct: 749 ILLQKVIRGFKDRSNFLKLKNAATLIQR------------------HWRGHNCRKNYGLM 790
Query: 2689 HRAATLIQSFYRMHRAKVDYETKKTAIVVIQNYYRLYVRVKTERKNFLAVQKSVRTIQAA 2748
+Q+ +R + Y + I+ Q R Y+ K R A V T+QA
Sbjct: 791 RLGFLRLQALHRSRKLHQQYRLARQRIIQFQARCRAYLVRKAFRHRLWA----VLTVQAY 846
Query: 2749 FRGMKVRQ 2756
RGM R+
Sbjct: 847 ARGMIARR 854
Score = 39.3 bits (90), Expect = 0.069
Identities = 51/213 (23%), Positives = 85/213 (39%), Gaps = 47/213 (22%)
Query: 1277 WRKYKLKTDLKRHQEREKAARIIQLAVINFLAKQRLRKRVNAALVIQKYWRRVLAQRKLL 1336
W+ K K LK H + L +R + + +++QK R + L
Sbjct: 719 WQIGKTKIFLKDHHDM-------------LLEVERDKAITDRVILLQKVIRGFKDRSNFL 765
Query: 1337 MLKKEKLEKVQNKAASLIQGYWRRYSTRQR-------FLKL----------------KYY 1373
LK AA+LIQ +WR ++ R+ FL+L +
Sbjct: 766 KLKN---------AATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQR 816
Query: 1374 SIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQ-RYEMLKSSTLIIQSMFR 1432
I Q+R R + +++ LWA +T+Q + R + R+ Q+ R E L +
Sbjct: 817 IIQFQARCRAYLVRKAFRHRLWAVLTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRLAE 876
Query: 1433 KWKQRKMQSQVKATVILQRAFREWHLRKQAKEE 1465
+ K RK S KA +R +E L + A+E+
Sbjct: 877 EEKLRKEMSAKKAKEEAERKHQE-RLAQLARED 908
Score = 38.9 bits (89), Expect = 0.090
Identities = 32/145 (22%), Positives = 63/145 (43%), Gaps = 8/145 (5%)
Query: 1972 KCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYRAYSIGREQNHLYLKTKAAVVTLQSAY 2031
K I ++ ++ M ++ ++ K + +L+QK R + + +LK K A +Q +
Sbjct: 723 KTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGF----KDRSNFLKLKNAATLIQRHW 778
Query: 2032 RGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKITNHQHKEYL 2091
RG RK + +Q+ +R+ K ++Y R I Q R + K +
Sbjct: 779 RGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQARCRAYLV----RKAFR 834
Query: 2092 NLKKTAIKIQSVYRGIRVRRHIQHM 2116
+ + +Q+ RG+ RR Q +
Sbjct: 835 HRLWAVLTVQAYARGMIARRLHQRL 859
Score = 37.4 bits (85), Expect = 0.26
Identities = 29/115 (25%), Positives = 55/115 (47%), Gaps = 16/115 (13%)
Query: 2558 IVIQSTYRMYRQYCFYQKLQWATKIIQEKYRANKKKQKVFQHNELKKETCVQAGF---QD 2614
I++Q R ++ + KL+ A +IQ +R HN K ++ GF Q
Sbjct: 749 ILLQKVIRGFKDRSNFLKLKNAATLIQRHWRG---------HNCRKNYGLMRLGFLRLQA 799
Query: 2615 MNIKKQIQEQHQAA----IIIQKHCKAFKIRKHYLHLRATVVSIQRRYRKLTAVR 2665
++ +++ +Q++ A I Q C+A+ +RK + H V+++Q R + A R
Sbjct: 800 LHRSRKLHQQYRLARQRIIQFQARCRAYLVRKAFRHRLWAVLTVQAYARGMIARR 854
Score = 35.8 bits (81), Expect = 0.76
Identities = 34/138 (24%), Positives = 63/138 (45%), Gaps = 13/138 (9%)
Query: 3124 IQRAYKLYLAVKNANKQVNSVICIQRWFRARL---------QEKRFIQKYHSIKKIEHEG 3174
++R L VK A KQ + QR A L + K F++ +H + +E E
Sbjct: 682 VERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQIGKTKIFLKDHHDML-LEVER 740
Query: 3175 QECLSQRNRAASVIQKAVRHFLLRKKQEKFTSGIIKIQALWRGYSWRKKNDCTKIKAIRL 3234
+ ++ R ++QK +R F R K + IQ WRG++ RK ++ +RL
Sbjct: 741 DKAITDR---VILLQKVIRGFKDRSNFLKLKNAATLIQRHWRGHNCRKNYGLMRLGFLRL 797
Query: 3235 SLQVVNREIREENKLYKR 3252
+R++ ++ +L ++
Sbjct: 798 QALHRSRKLHQQYRLARQ 815
Score = 35.8 bits (81), Expect = 0.76
Identities = 40/176 (22%), Positives = 70/176 (39%), Gaps = 28/176 (15%)
Query: 2454 FLHLRKAAITIQSSYRRLMVKKKLQEMQRAAVLIQATFRMYRTYITFQTWKHASILIQQH 2513
FL L+ AA IQ +R +K M+ + +QA R + + ++ + I Q
Sbjct: 764 FLKLKNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQAR 823
Query: 2514 YRTYRAAKLQRENYIRQWHSAVVIQAAYKGMKARQL------------------------ 2549
R Y K R R W + + +QA +GM AR+L
Sbjct: 824 CRAYLVRKAFRH---RLW-AVLTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRLAEEEK 879
Query: 2550 LREKHKASIVIQSTYRMYRQYCFYQKLQWATKIIQEKYRANKKKQKVFQHNELKKE 2605
LR++ A + R +++ + A + ++EK A +KK+ + Q + E
Sbjct: 880 LRKEMSAKKAKEEAERKHQERLAQLAREDAERELKEKEAARRKKELLEQMERARHE 935
>gi|189083798 myosin VIIA isoform 1 [Homo sapiens]
Length = 2215
Score = 64.3 bits (155), Expect = 2e-09
Identities = 50/182 (27%), Positives = 87/182 (47%), Gaps = 5/182 (2%)
Query: 1655 ILTSVIKIQSYYRAYVSKKEFLSLKNATIKLQSTVKMKQTRKQYLHLRAAALFIQQCYRS 1714
I VI +Q R + + FL LKNA +Q + RK Y +R L +Q +RS
Sbjct: 744 ITDRVILLQKVIRGFKDRSNFLKLKNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRS 803
Query: 1715 KKIAAQKREEYMQMRESCIKLQAFVRGYLVRKQMRLQRKAVISLQSYFRMRKARQYYLKM 1774
+K+ ++Y R+ I+ QA R YLVRK R + AV+++Q+Y R AR+ + ++
Sbjct: 804 RKL----HQQYRLARQRIIQFQARCRAYLVRKAFRHRLWAVLTVQAYARGMIARRLHQRL 859
Query: 1775 YKAIIVIQNYYHAYKAQVNQRKNFLQVKKAATCLQAAYRGYKVRQLIKQQSIAALKIQSA 1834
+ A+ + + + KKA + ++ ++ QL ++ + LK + A
Sbjct: 860 RAEYLWRLEAEKMRLAEEEKLRKEMSAKKAKEEAERKHQ-ERLAQLAREDAERELKEKEA 918
Query: 1835 FR 1836
R
Sbjct: 919 AR 920
Score = 52.4 bits (124), Expect = 8e-06
Identities = 36/129 (27%), Positives = 64/129 (49%), Gaps = 6/129 (4%)
Query: 2231 IQFQRYNKLRHSVIYIQAIFRGKKARRHLKMMHIAATLIQRRFRTLMMRRRFLSLKKTAI 2290
++ +R + VI +Q + RG K R + + AATLIQR +R R+ + ++ +
Sbjct: 736 LEVERDKAITDRVILLQKVIRGFKDRSNFLKLKNAATLIQRHWRGHNCRKNYGLMRLGFL 795
Query: 2291 LIQRKYRAHLCTKHHLQFLQVQNAVIKIQSSYRRWMIRKRMREMHRAATFIQSTFR---M 2347
+Q +R+ K H Q+ + +I+ Q+ R +++RK R A +Q+ R
Sbjct: 796 RLQALHRSR---KLHQQYRLARQRIIQFQARCRAYLVRKAFRHRLWAVLTVQAYARGMIA 852
Query: 2348 HRLHMRYQA 2356
RLH R +A
Sbjct: 853 RRLHQRLRA 861
Score = 51.2 bits (121), Expect = 2e-05
Identities = 39/141 (27%), Positives = 71/141 (50%), Gaps = 12/141 (8%)
Query: 1778 IIVIQNYYHAYKAQVNQRKNFLQVKKAATCLQAAYRGYKVRQLIKQQSIAALKIQSAFRG 1837
+I++Q +K R NFL++K AAT +Q +RG+ R+ + L++Q+ R
Sbjct: 748 VILLQKVIRGFK----DRSNFLKLKNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRS 803
Query: 1838 YNKRVKYQSVLQSIIKIQRWYRAYKTLHDTRTHFLKTKAAVISLQSAYRGW---KVRKQI 1894
+Y+ Q II+ Q RAY R F AV+++Q+ RG ++ +++
Sbjct: 804 RKLHQQYRLARQRIIQFQARCRAYL----VRKAFRHRLWAVLTVQAYARGMIARRLHQRL 859
Query: 1895 RREHQAALKIQSAFRMAKAQK 1915
R E+ L+ + R+A+ +K
Sbjct: 860 RAEYLWRLEAEK-MRLAEEEK 879
Score = 50.4 bits (119), Expect = 3e-05
Identities = 50/206 (24%), Positives = 93/206 (45%), Gaps = 15/206 (7%)
Query: 1528 KIERTNYLQKRAAAIQLQAAFRRLKAH-NLCRQIRAACVIQSYWRMRQDRVRFLNLKKTI 1586
++ER + R I LQ R K N + AA +IQ +WR R + ++
Sbjct: 737 EVERDKAITDRV--ILLQKVIRGFKDRSNFLKLKNAATLIQRHWRGHNCRKNYGLMRLGF 794
Query: 1587 IKFQAHVRKHQQRQKYKKMKKAAVIIQTHFRAYIFAMKVLASYQKTRSAVIVLQSAYRGM 1646
++ QA R + Q+Y+ ++ + Q RAY+ V +++ AV+ +Q+ RGM
Sbjct: 795 LRLQALHRSRKLHQQYRLARQRIIQFQARCRAYL----VRKAFRHRLWAVLTVQAYARGM 850
Query: 1647 QARKMYIHILTSVIKIQSYYRAYVSKKEFLSLKNATIKLQSTVKMKQTRKQYLHLRAAAL 1706
AR+++ + Y ++K L+ + K S K K+ ++ R A L
Sbjct: 851 IARRLHQRLRA------EYLWRLEAEKMRLAEEEKLRKEMSAKKAKEEAERKHQERLAQL 904
Query: 1707 FIQQCYR--SKKIAAQKREEYMQMRE 1730
+ R +K AA++++E ++ E
Sbjct: 905 AREDAERELKEKEAARRKKELLEQME 930
Score = 49.7 bits (117), Expect = 5e-05
Identities = 34/146 (23%), Positives = 68/146 (46%), Gaps = 4/146 (2%)
Query: 1586 IIKFQAHVRKHQQRQKYKKMKKAAVIIQTHFRAYIFAMKVLASYQKTRSAVIVLQSAYRG 1645
+I Q +R + R + K+K AA +IQ H+R + +Y R + LQ+ +R
Sbjct: 748 VILLQKVIRGFKDRSNFLKLKNAATLIQRHWRGH----NCRKNYGLMRLGFLRLQALHRS 803
Query: 1646 MQARKMYIHILTSVIKIQSYYRAYVSKKEFLSLKNATIKLQSTVKMKQTRKQYLHLRAAA 1705
+ + Y +I+ Q+ RAY+ +K F A + +Q+ + R+ + LRA
Sbjct: 804 RKLHQQYRLARQRIIQFQARCRAYLVRKAFRHRLWAVLTVQAYARGMIARRLHQRLRAEY 863
Query: 1706 LFIQQCYRSKKIAAQKREEYMQMRES 1731
L+ + + + +K + M +++
Sbjct: 864 LWRLEAEKMRLAEEEKLRKEMSAKKA 889
Score = 49.3 bits (116), Expect = 7e-05
Identities = 52/197 (26%), Positives = 92/197 (46%), Gaps = 20/197 (10%)
Query: 3021 HEHFLMIKRHRA----ACLIQAHYRGYKGRQVFLRQKSAALIIQKYIRAREAGKHERIKY 3076
H+ L ++R +A L+Q RG+K R FL+ K+AA +IQ++ R K+ +
Sbjct: 732 HDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKLKNAATLIQRHWRGHNCRKNYGLMR 791
Query: 3077 IEFKKSTVILQALVRG-------WLVRKRFLEQRAKIRLLHFTAAAYYHLNAVRIQRAYK 3129
+ F + LQAL R L R+R ++ +A+ R A + L AV +AY
Sbjct: 792 LGFLR----LQALHRSRKLHQQYRLARQRIIQFQARCRAYLVRKAFRHRLWAVLTVQAYA 847
Query: 3130 LYLAVKNANKQVNS-VICIQRWFRARLQEKRFIQKYHSIKKIEHEG----QECLSQRNRA 3184
+ + ++++ + + + RL E+ ++K S KK + E QE L+Q R
Sbjct: 848 RGMIARRLHQRLRAEYLWRLEAEKMRLAEEEKLRKEMSAKKAKEEAERKHQERLAQLARE 907
Query: 3185 ASVIQKAVRHFLLRKKQ 3201
+ + + RKK+
Sbjct: 908 DAERELKEKEAARRKKE 924
Score = 49.3 bits (116), Expect = 7e-05
Identities = 43/166 (25%), Positives = 71/166 (42%), Gaps = 9/166 (5%)
Query: 2071 IIIQRWYRGIKITNHQHKEYLNLKKTAIKIQSVYRGIRVRRHIQHMHRAATFIKAMFKMH 2130
I++Q+ RG K +L LK A IQ +RG R++ M ++A+ +
Sbjct: 749 ILLQKVIRGFK----DRSNFLKLKNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRSR 804
Query: 2131 QSRISYHTMRKAAIVIQVRCRAYYQGKMQREKYLTILKAVKVLQASFRGVRVRRTLRKMQ 2190
+ Y R+ I Q RCRAY K R + L AV +QA RG+ RR ++++
Sbjct: 805 KLHQQYRLARQRIIQFQARCRAYLVRKAFRHR----LWAVLTVQAYARGMIARRLHQRLR 860
Query: 2191 TA-ATLIQSNYRRYRQQTYFNKLKKITKTVQQRYWAMKERNIQFQR 2235
+++ R ++ K K ++ +ER Q R
Sbjct: 861 AEYLWRLEAEKMRLAEEEKLRKEMSAKKAKEEAERKHQERLAQLAR 906
Score = 48.9 bits (115), Expect = 9e-05
Identities = 65/317 (20%), Positives = 132/317 (41%), Gaps = 44/317 (13%)
Query: 1732 CIKLQAFVRGYLVRKQMRLQRKAVISLQSYFRMRKARQYYLKMYKAIIVIQNYY------ 1785
CIK F + L + + +++ + R+R+A Y Y + ++ Y
Sbjct: 635 CIKPNEFKKPMLFDRHLCVRQLRYSGMMETIRIRRAG--YPIRYSFVEFVERYRVLLPGV 692
Query: 1786 -HAYKAQVNQRKNFLQVKKAATCLQAAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRVKY 1844
AYK Q + R ++ +A ++ K + +K L+++ +
Sbjct: 693 KPAYK-QGDLRGTCQRMAEAVLGTHDDWQIGKTKIFLKDHHDMLLEVE----------RD 741
Query: 1845 QSVLQSIIKIQRWYRAYKTLHDTRTHFLKTKAAVISLQSAYRGWKVRKQIRREHQAALKI 1904
+++ +I +Q+ R +K R++FLK K A +Q +RG RK L++
Sbjct: 742 KAITDRVILLQKVIRGFKD----RSNFLKLKNAATLIQRHWRGHNCRKNYGLMRLGFLRL 797
Query: 1905 QSAFRMAKAQKQFRLFKTAALVIQQNFRAWTAGRKQCMEYIELRH---AVLVLQSMWKGK 1961
Q+ R K +Q+RL + + Q RA+ + RH AVL +Q+ +G
Sbjct: 798 QALHRSRKLHQQYRLARQRIIQFQARCRAYLVRK-------AFRHRLWAVLTVQAYARGM 850
Query: 1962 TLRRQLQRQHKCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYRAYSIGREQNHLYLKTK 2021
RR QR +++ Y ++ +K ++ ++ L + + E+ H + +
Sbjct: 851 IARRLHQR-------LRAEYLWRLEAEKMRLAEEEKLRKEMSAKKAKEEAERKH---QER 900
Query: 2022 AAVVTLQSAYRGMKVRK 2038
A + + A R +K ++
Sbjct: 901 LAQLAREDAERELKEKE 917
Score = 47.8 bits (112), Expect = 2e-04
Identities = 44/198 (22%), Positives = 97/198 (48%), Gaps = 8/198 (4%)
Query: 1415 QRYEMLKSSTLIIQSMFRKWKQRKMQSQVK-ATVILQRAFREWHLRKQAKEENSAII-IQ 1472
+R + + +++Q + R +K R ++K A ++QR +R + RK + +Q
Sbjct: 739 ERDKAITDRVILLQKVIRGFKDRSNFLKLKNAATLIQRHWRGHNCRKNYGLMRLGFLRLQ 798
Query: 1473 SWYRMHKELRKYIYIRSCVVIIQKRFRCFQAQKLYKRRKESILTIQKYYKAYLKGKIERT 1532
+ +R K ++Y R ++ Q R R + +K ++ R ++LT+Q AY +G I R
Sbjct: 799 ALHRSRKLHQQYRLARQRIIQFQARCRAYLVRKAFRHRLWAVLTVQ----AYARGMIARR 854
Query: 1533 NYLQKRAAAI-QLQAAFRRL-KAHNLCRQIRAACVIQSYWRMRQDRVRFLNLKKTIIKFQ 1590
+ + RA + +L+A RL + L +++ A + R Q+R+ L + + +
Sbjct: 855 LHQRLRAEYLWRLEAEKMRLAEEEKLRKEMSAKKAKEEAERKHQERLAQLAREDAERELK 914
Query: 1591 AHVRKHQQRQKYKKMKKA 1608
++++ ++M++A
Sbjct: 915 EKEAARRKKELLEQMERA 932
Score = 47.4 bits (111), Expect = 3e-04
Identities = 55/214 (25%), Positives = 96/214 (44%), Gaps = 22/214 (10%)
Query: 2276 LMMRRRFLSLKKTAILIQRKYRAHLCTKHHLQFLQVQNAVIKIQSSYRRWMIRKRMREMH 2335
L+ R ++ IL+Q+ R K FL+++NA IQ +R RK M
Sbjct: 735 LLEVERDKAITDRVILLQKVIRGF---KDRSNFLKLKNAATLIQRHWRGHNCRKNYGLMR 791
Query: 2336 RAATFIQSTFRMHRLHMRYQALKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAF 2395
+Q+ R +LH +Y+ +Q + Q+QA A L R+ + + + + +QA
Sbjct: 792 LGFLRLQALHRSRKLHQQYRLARQRII----QFQARCRAYLVRKAFRHRLWAVLTVQAYA 847
Query: 2396 RGMKTRRHLKSMHSSATLIQSRFRSLLVR----RRFISLKKATIFVQRKYRATIC--AKH 2449
RGM RR + + + + L R+ +S KKA +RK++ + A+
Sbjct: 848 RGMIARRLHQRLRAEYLWRLEAEKMRLAEEEKLRKEMSAKKAKEEAERKHQERLAQLARE 907
Query: 2450 KLYQFLHLRKAAITIQSSYRRLMVKKKLQEMQRA 2483
+ L ++AA RR K+ L++M+RA
Sbjct: 908 DAERELKEKEAA-------RR--KKELLEQMERA 932
Score = 45.4 bits (106), Expect = 0.001
Identities = 35/139 (25%), Positives = 58/139 (41%), Gaps = 15/139 (10%)
Query: 2024 VVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKIT 2083
V+ LQ RG K R AA IQ +R + +K Y R + +Q +R K+
Sbjct: 748 VILLQKVIRGFKDRSNFLKLKNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKL- 806
Query: 2084 NHQHKEYLNLKKTAIKIQSVYRGIRVRRHIQHMHRAATFIKAMFKMHQSRISYHTMRKAA 2143
H++Y ++ I+ Q+ R VR+ +H A ++A + A
Sbjct: 807 ---HQQYRLARQRIIQFQARCRAYLVRKAFRHRLWAVLTVQA-----------YARGMIA 852
Query: 2144 IVIQVRCRAYYQGKMQREK 2162
+ R RA Y +++ EK
Sbjct: 853 RRLHQRLRAEYLWRLEAEK 871
Score = 43.9 bits (102), Expect = 0.003
Identities = 48/233 (20%), Positives = 97/233 (41%), Gaps = 32/233 (13%)
Query: 2157 KMQREKYLTILKAVKVLQASFRGVRVRRTLRKMQTAATLIQSNYRRYRQQTYFNKLKKIT 2216
+++R+K +T V +LQ RG + R K++ AATLIQ ++R + +
Sbjct: 737 EVERDKAIT--DRVILLQKVIRGFKDRSNFLKLKNAATLIQRHWRGHNCR---------- 784
Query: 2217 KTVQQRYWAMKERNIQFQRYNKLRHSVIYIQAIFRGKKARRHLKMMHIAATLIQRRFRTL 2276
+ Y +R + +QA+ R +K + ++ Q R R
Sbjct: 785 -----------------KNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQARCRAY 827
Query: 2277 MMRRRFLSLKKTAILIQRKYRAHLCTKHHLQFLQVQNAVIKIQSSYRRWMIRKRMREMHR 2336
++R+ F + +Q R + + H Q L+ + + ++++ R +++R+
Sbjct: 828 LVRKAFRHRLWAVLTVQAYARGMIARRLH-QRLRAE-YLWRLEAEKMRLAEEEKLRKEMS 885
Query: 2337 AATFIQSTFRMHRLHMRYQALKQASVVIQQQYQANRAAKLQRQHYLRQRHSAV 2389
A + R H+ + A + A ++++ A R +L Q R RH V
Sbjct: 886 AKKAKEEAERKHQERLAQLAREDAERELKEKEAARRKKELLEQ-MERARHEPV 937
Score = 43.5 bits (101), Expect = 0.004
Identities = 48/200 (24%), Positives = 84/200 (42%), Gaps = 34/200 (17%)
Query: 2884 KAAVVLQNHYRAFLSAKHQRQVYLQIRSSVIIIQARSKGFIQKRKFQEIKNSTIKIQAMW 2943
K + L++H+ L + + I VI++Q +GF + F ++KN+ IQ W
Sbjct: 723 KTKIFLKDHHDMLLEVERDKA----ITDRVILLQKVIRGFKDRSNFLKLKNAATLIQRHW 778
Query: 2944 RRYRAKK-YLCKVKAACKIQAWYRCWRAHKEYLAILKAVKIIQGCFYTKLERTRFLNVRA 3002
R + +K Y ++QA +R + H++Y +L R R +
Sbjct: 779 RGHNCRKNYGLMRLGFLRLQALHRSRKLHQQY----------------RLARQRIIQ--- 819
Query: 3003 SAIIIQRKWRAILPAKIAHEHFLMIKRHRAACLIQAHYRGYKGRQVFLRQKSAALIIQKY 3062
Q + RA L K A H L A +QA+ RG R++ R ++ L +
Sbjct: 820 ----FQARCRAYLVRK-AFRHRLW-----AVLTVQAYARGMIARRLHQRLRAEYLWRLEA 869
Query: 3063 IRAREAGKHERIKYIEFKKS 3082
+ R A + + K + KK+
Sbjct: 870 EKMRLAEEEKLRKEMSAKKA 889
Score = 42.4 bits (98), Expect = 0.008
Identities = 27/90 (30%), Positives = 44/90 (48%), Gaps = 5/90 (5%)
Query: 2666 TQAVICIQSYYRGFKVRKDIQNMHRAATLIQSFYRMHRAKVDYETKKTAIVVIQNYYR-- 2723
T VI +Q RGFK R + + AATLIQ +R H + +Y + + +Q +R
Sbjct: 745 TDRVILLQKVIRGFKDRSNFLKLKNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRSR 804
Query: 2724 -LYVRVKTERKNFLAVQKSVRT--IQAAFR 2750
L+ + + R+ + Q R ++ AFR
Sbjct: 805 KLHQQYRLARQRIIQFQARCRAYLVRKAFR 834
Score = 40.8 bits (94), Expect = 0.024
Identities = 28/118 (23%), Positives = 56/118 (47%), Gaps = 4/118 (3%)
Query: 1951 VLVLQSMWKGKTLRRQLQRQHKCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYRAYSIG 2010
V++LQ + +G R + A +IQ ++R H +K + +M+ L +Q +R+
Sbjct: 748 VILLQKVIRGFKDRSNFLKLKNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRS---- 803
Query: 2011 REQNHLYLKTKAAVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYATYRA 2068
R+ + Y + ++ Q+ R VRK + A +T+Q+ R ++ + RA
Sbjct: 804 RKLHQQYRLARQRIIQFQARCRAYLVRKAFRHRLWAVLTVQAYARGMIARRLHQRLRA 861
Score = 40.4 bits (93), Expect = 0.031
Identities = 36/180 (20%), Positives = 73/180 (40%), Gaps = 22/180 (12%)
Query: 2459 KAAITIQSSYRRLMVKKKLQEMQRAAVLIQATFRMYRTYITFQTWKHASILIQQHYRTYR 2518
K I ++ + L+ ++ + + +L+Q R ++ F K+A+ LIQ+H+R +
Sbjct: 723 KTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKLKNAATLIQRHWRGHN 782
Query: 2519 AAKLQRENYIRQWHSAVVIQAAYKGMKARQLLREKHKASIVIQSTYRMYRQYCFYQKLQW 2578
R+NY + +QA ++ K Q R + I Q+ R Y ++ W
Sbjct: 783 C----RKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQARCRAYLVRKAFRHRLW 838
Query: 2579 ATKIIQE------------------KYRANKKKQKVFQHNELKKETCVQAGFQDMNIKKQ 2620
A +Q +R +K ++ + +L+KE + ++ K Q
Sbjct: 839 AVLTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRLAEEEKLRKEMSAKKAKEEAERKHQ 898
Score = 40.4 bits (93), Expect = 0.031
Identities = 34/128 (26%), Positives = 52/128 (40%), Gaps = 22/128 (17%)
Query: 2629 IIIQKHCKAFKIRKHYLHLRATVVSIQRRYRKLTAVRTQAVICIQSYYRGFKVRKDIQNM 2688
I++QK + FK R ++L L+ IQR ++RG RK+ M
Sbjct: 749 ILLQKVIRGFKDRSNFLKLKNAATLIQR------------------HWRGHNCRKNYGLM 790
Query: 2689 HRAATLIQSFYRMHRAKVDYETKKTAIVVIQNYYRLYVRVKTERKNFLAVQKSVRTIQAA 2748
+Q+ +R + Y + I+ Q R Y+ K R A V T+QA
Sbjct: 791 RLGFLRLQALHRSRKLHQQYRLARQRIIQFQARCRAYLVRKAFRHRLWA----VLTVQAY 846
Query: 2749 FRGMKVRQ 2756
RGM R+
Sbjct: 847 ARGMIARR 854
Score = 39.3 bits (90), Expect = 0.069
Identities = 51/213 (23%), Positives = 85/213 (39%), Gaps = 47/213 (22%)
Query: 1277 WRKYKLKTDLKRHQEREKAARIIQLAVINFLAKQRLRKRVNAALVIQKYWRRVLAQRKLL 1336
W+ K K LK H + L +R + + +++QK R + L
Sbjct: 719 WQIGKTKIFLKDHHDM-------------LLEVERDKAITDRVILLQKVIRGFKDRSNFL 765
Query: 1337 MLKKEKLEKVQNKAASLIQGYWRRYSTRQR-------FLKL----------------KYY 1373
LK AA+LIQ +WR ++ R+ FL+L +
Sbjct: 766 KLKN---------AATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQR 816
Query: 1374 SIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQ-RYEMLKSSTLIIQSMFR 1432
I Q+R R + +++ LWA +T+Q + R + R+ Q+ R E L +
Sbjct: 817 IIQFQARCRAYLVRKAFRHRLWAVLTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRLAE 876
Query: 1433 KWKQRKMQSQVKATVILQRAFREWHLRKQAKEE 1465
+ K RK S KA +R +E L + A+E+
Sbjct: 877 EEKLRKEMSAKKAKEEAERKHQE-RLAQLARED 908
Score = 38.9 bits (89), Expect = 0.090
Identities = 32/145 (22%), Positives = 63/145 (43%), Gaps = 8/145 (5%)
Query: 1972 KCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYRAYSIGREQNHLYLKTKAAVVTLQSAY 2031
K I ++ ++ M ++ ++ K + +L+QK R + + +LK K A +Q +
Sbjct: 723 KTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGF----KDRSNFLKLKNAATLIQRHW 778
Query: 2032 RGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKITNHQHKEYL 2091
RG RK + +Q+ +R+ K ++Y R I Q R + K +
Sbjct: 779 RGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQARCRAYLV----RKAFR 834
Query: 2092 NLKKTAIKIQSVYRGIRVRRHIQHM 2116
+ + +Q+ RG+ RR Q +
Sbjct: 835 HRLWAVLTVQAYARGMIARRLHQRL 859
Score = 37.4 bits (85), Expect = 0.26
Identities = 29/115 (25%), Positives = 55/115 (47%), Gaps = 16/115 (13%)
Query: 2558 IVIQSTYRMYRQYCFYQKLQWATKIIQEKYRANKKKQKVFQHNELKKETCVQAGF---QD 2614
I++Q R ++ + KL+ A +IQ +R HN K ++ GF Q
Sbjct: 749 ILLQKVIRGFKDRSNFLKLKNAATLIQRHWRG---------HNCRKNYGLMRLGFLRLQA 799
Query: 2615 MNIKKQIQEQHQAA----IIIQKHCKAFKIRKHYLHLRATVVSIQRRYRKLTAVR 2665
++ +++ +Q++ A I Q C+A+ +RK + H V+++Q R + A R
Sbjct: 800 LHRSRKLHQQYRLARQRIIQFQARCRAYLVRKAFRHRLWAVLTVQAYARGMIARR 854
Score = 35.8 bits (81), Expect = 0.76
Identities = 34/138 (24%), Positives = 63/138 (45%), Gaps = 13/138 (9%)
Query: 3124 IQRAYKLYLAVKNANKQVNSVICIQRWFRARL---------QEKRFIQKYHSIKKIEHEG 3174
++R L VK A KQ + QR A L + K F++ +H + +E E
Sbjct: 682 VERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQIGKTKIFLKDHHDML-LEVER 740
Query: 3175 QECLSQRNRAASVIQKAVRHFLLRKKQEKFTSGIIKIQALWRGYSWRKKNDCTKIKAIRL 3234
+ ++ R ++QK +R F R K + IQ WRG++ RK ++ +RL
Sbjct: 741 DKAITDR---VILLQKVIRGFKDRSNFLKLKNAATLIQRHWRGHNCRKNYGLMRLGFLRL 797
Query: 3235 SLQVVNREIREENKLYKR 3252
+R++ ++ +L ++
Sbjct: 798 QALHRSRKLHQQYRLARQ 815
Score = 35.8 bits (81), Expect = 0.76
Identities = 40/176 (22%), Positives = 70/176 (39%), Gaps = 28/176 (15%)
Query: 2454 FLHLRKAAITIQSSYRRLMVKKKLQEMQRAAVLIQATFRMYRTYITFQTWKHASILIQQH 2513
FL L+ AA IQ +R +K M+ + +QA R + + ++ + I Q
Sbjct: 764 FLKLKNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQAR 823
Query: 2514 YRTYRAAKLQRENYIRQWHSAVVIQAAYKGMKARQL------------------------ 2549
R Y K R R W + + +QA +GM AR+L
Sbjct: 824 CRAYLVRKAFRH---RLW-AVLTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRLAEEEK 879
Query: 2550 LREKHKASIVIQSTYRMYRQYCFYQKLQWATKIIQEKYRANKKKQKVFQHNELKKE 2605
LR++ A + R +++ + A + ++EK A +KK+ + Q + E
Sbjct: 880 LRKEMSAKKAKEEAERKHQERLAQLAREDAERELKEKEAARRKKELLEQMERARHE 935
>gi|122937512 myosin VIIB [Homo sapiens]
Length = 2116
Score = 63.5 bits (153), Expect = 3e-09
Identities = 37/114 (32%), Positives = 64/114 (56%), Gaps = 4/114 (3%)
Query: 1658 SVIKIQSYYRAYVSKKEFLSLKNATIKLQSTVKMKQTRKQYLHLRAAALFIQQCYRSKKI 1717
+ + IQ R Y +KEFL + A + LQ+ + R+ + + +Q RS+ +
Sbjct: 766 AALSIQKVLRGYRYRKEFLRQRRAAVTLQAWWRGYCNRRNFKLILVGFERLQAIARSQPL 825
Query: 1718 AAQKREEYMQMRESCIKLQAFVRGYLVRKQMRLQRKAVISLQSYFRMRKARQYY 1771
A Q Y MR+ ++LQA RGYLVR+Q++ +R+AV+ +Q++ R AR+ +
Sbjct: 826 ARQ----YQAMRQRTVQLQALCRGYLVRQQVQAKRRAVVVIQAHARGMAARRNF 875
Score = 54.3 bits (129), Expect = 2e-06
Identities = 38/125 (30%), Positives = 64/125 (51%), Gaps = 5/125 (4%)
Query: 1528 KIERTNYLQKRAAAIQLQAAFRRLKAHNLCRQIRAACVIQSYWRMRQDRVRFLNLKKTII 1587
+++R+ L + A +IQ R + L RQ RAA +Q++WR +R F +
Sbjct: 756 EVQRSQVLDRAALSIQKVLRGYRYRKEFL-RQRRAAVTLQAWWRGYCNRRNFKLILVGFE 814
Query: 1588 KFQAHVRKHQQRQKYKKMKKAAVIIQTHFRAYIFAMKVLASYQKTRSAVIVLQSAYRGMQ 1647
+ QA R ++Y+ M++ V +Q R Y+ +V Q R AV+V+Q+ RGM
Sbjct: 815 RLQAIARSQPLARQYQAMRQRTVQLQALCRGYLVRQQV----QAKRRAVVVIQAHARGMA 870
Query: 1648 ARKMY 1652
AR+ +
Sbjct: 871 ARRNF 875
Score = 54.3 bits (129), Expect = 2e-06
Identities = 31/124 (25%), Positives = 68/124 (54%), Gaps = 4/124 (3%)
Query: 1877 AVISLQSAYRGWKVRKQIRREHQAALKIQSAFRMAKAQKQFRLFKTAALVIQQNFRAWTA 1936
A +S+Q RG++ RK+ R+ +AA+ +Q+ +R ++ F+L LV + +A
Sbjct: 766 AALSIQKVLRGYRYRKEFLRQRRAAVTLQAWWRGYCNRRNFKLI----LVGFERLQAIAR 821
Query: 1937 GRKQCMEYIELRHAVLVLQSMWKGKTLRRQLQRQHKCAIIIQSYYRMHVQQKKWKIMKKA 1996
+ +Y +R + LQ++ +G +R+Q+Q + + ++IQ++ R ++ ++ K
Sbjct: 822 SQPLARQYQAMRQRTVQLQALCRGYLVRQQVQAKRRAVVVIQAHARGMAARRNFQQRKAN 881
Query: 1997 ALLI 2000
A L+
Sbjct: 882 APLV 885
Score = 53.5 bits (127), Expect = 4e-06
Identities = 41/123 (33%), Positives = 61/123 (49%), Gaps = 20/123 (16%)
Query: 2839 AALRIQFFLQMAVYRRRFVQQKRAAITLQHYFRTWQTRKQFLLY-----RKAAVVLQNHY 2893
AAL IQ L+ YR+ F++Q+RAA+TLQ ++R + R+ F L R A+
Sbjct: 766 AALSIQKVLRGYRYRKEFLRQRRAAVTLQAWWRGYCNRRNFKLILVGFERLQAIARSQPL 825
Query: 2894 RAFLSAKHQRQVYLQI--------------RSSVIIIQARSKGFIQKRKFQEIK-NSTIK 2938
A QR V LQ R +V++IQA ++G +R FQ+ K N+ +
Sbjct: 826 ARQYQAMRQRTVQLQALCRGYLVRQQVQAKRRAVVVIQAHARGMAARRNFQQRKANAPLV 885
Query: 2939 IQA 2941
I A
Sbjct: 886 IPA 888
Score = 52.0 bits (123), Expect = 1e-05
Identities = 38/135 (28%), Positives = 71/135 (52%), Gaps = 8/135 (5%)
Query: 2353 RYQALKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAFRGMKTRRHLKSMHSSAT 2412
R Q L +A++ IQ+ + R R+ +LRQR +AV LQA +RG RR+ K +
Sbjct: 759 RSQVLDRAALSIQKVLRGYR----YRKEFLRQRRAAVTLQAWWRGYCNRRNFKLILVGFE 814
Query: 2413 LIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKHKLYQFLHLRKAAITIQSSYRRLM 2472
+Q+ RS + R++ ++++ T+ +Q R + + Q R+A + IQ+ R +
Sbjct: 815 RLQAIARSQPLARQYQAMRQRTVQLQALCRGYLVRQ----QVQAKRRAVVVIQAHARGMA 870
Query: 2473 VKKKLQEMQRAAVLI 2487
++ Q+ + A L+
Sbjct: 871 ARRNFQQRKANAPLV 885
Score = 51.6 bits (122), Expect = 1e-05
Identities = 34/128 (26%), Positives = 65/128 (50%), Gaps = 8/128 (6%)
Query: 2069 SAIIIQRWYRGIKITNHQHKEYLNLKKTAIKIQSVYRGIRVRRHIQHMHRAATFIKAMFK 2128
+A+ IQ+ RG + KE+L ++ A+ +Q+ +RG RR+ + + ++A+ +
Sbjct: 766 AALSIQKVLRGYRY----RKEFLRQRRAAVTLQAWWRGYCNRRNFKLILVGFERLQAIAR 821
Query: 2129 MHQSRISYHTMRKAAIVIQVRCRAYYQGKMQREKYLTILKAVKVLQASFRGVRVRRTLRK 2188
Y MR+ + +Q CR Y + R++ +AV V+QA RG+ RR ++
Sbjct: 822 SQPLARQYQAMRQRTVQLQALCRGY----LVRQQVQAKRRAVVVIQAHARGMAARRNFQQ 877
Query: 2189 MQTAATLI 2196
+ A L+
Sbjct: 878 RKANAPLV 885
Score = 51.2 bits (121), Expect = 2e-05
Identities = 32/115 (27%), Positives = 64/115 (55%), Gaps = 5/115 (4%)
Query: 2861 RAAITLQHYFRTWQTRKQFLLYRKAAVVLQNHYRAFLSAKHQRQVYLQIRSSVIIIQARS 2920
RAA+++Q R ++ RK+FL R+AAV LQ +R + + ++ + + + +QA +
Sbjct: 765 RAALSIQKVLRGYRYRKEFLRQRRAAVTLQAWWRGYCNRRNFKLILVGFER----LQAIA 820
Query: 2921 KGFIQKRKFQEIKNSTIKIQAMWRRYRAKKYL-CKVKAACKIQAWYRCWRAHKEY 2974
+ R++Q ++ T+++QA+ R Y ++ + K +A IQA R A + +
Sbjct: 821 RSQPLARQYQAMRQRTVQLQALCRGYLVRQQVQAKRRAVVVIQAHARGMAARRNF 875
Score = 49.7 bits (117), Expect = 5e-05
Identities = 42/179 (23%), Positives = 80/179 (44%), Gaps = 13/179 (7%)
Query: 1946 ELRHAVLVLQSMWKGKTLRRQLQ-RQHKCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYY 2004
+LR L + +W LR + K I ++ + ++ ++ +++ +AAL IQK
Sbjct: 719 KLRQMTLGITDVW----LRTDKDWKAGKTKIFLRDHQDTLLEVQRSQVLDRAALSIQKVL 774
Query: 2005 RAYSIGREQNHLYLKTKAAVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYA 2064
R Y +E +L+ + A VTLQ+ +RG R+ K +Q+ R+ ++Y
Sbjct: 775 RGYRYRKE----FLRQRRAAVTLQAWWRGYCNRRNFKLILVGFERLQAIARSQPLARQYQ 830
Query: 2065 TYRASAIIIQRWYRGIKITNHQHKEYLNLKKTAIKIQSVYRGIRVRRHIQHMHRAATFI 2123
R + +Q RG + + ++ + IQ+ RG+ RR+ Q A +
Sbjct: 831 AMRQRTVQLQALCRGYLVRQQVQAK----RRAVVVIQAHARGMAARRNFQQRKANAPLV 885
Score = 47.4 bits (111), Expect = 3e-04
Identities = 33/152 (21%), Positives = 71/152 (46%), Gaps = 19/152 (12%)
Query: 2038 KRIKDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRG------------------ 2079
+R + ++AA++IQ R Y+ +K++ R +A+ +Q W+RG
Sbjct: 758 QRSQVLDRAALSIQKVLRGYRYRKEFLRQRRAAVTLQAWWRGYCNRRNFKLILVGFERLQ 817
Query: 2080 -IKITNHQHKEYLNLKKTAIKIQSVYRGIRVRRHIQHMHRAATFIKAMFKMHQSRISYHT 2138
I + ++Y +++ +++Q++ RG VR+ +Q RA I+A + +R ++
Sbjct: 818 AIARSQPLARQYQAMRQRTVQLQALCRGYLVRQQVQAKRRAVVVIQAHARGMAARRNFQQ 877
Query: 2139 MRKAAIVIQVRCRAYYQGKMQREKYLTILKAV 2170
+ A ++ QG + +K +I V
Sbjct: 878 RKANAPLVIPAEGQKSQGALPAKKRRSIYDTV 909
Score = 47.0 bits (110), Expect = 3e-04
Identities = 34/147 (23%), Positives = 71/147 (48%), Gaps = 7/147 (4%)
Query: 2914 IIIQARSKGFIQKRKFQEIKNSTIKIQAMWRRYRAKK-YLCKVKAACKIQAWYRCWRAHK 2972
I ++ ++ ++ Q + + + IQ + R YR +K +L + +AA +QAW+R + +
Sbjct: 745 IFLRDHQDTLLEVQRSQVLDRAALSIQKVLRGYRYRKEFLRQRRAAVTLQAWWRGYCNRR 804
Query: 2973 EYLAILKAVKIIQGCFYTKLERTRFLNVRASAIIIQRKWRAILPAKIAHEHFLMIKRHRA 3032
+ IL + +Q ++ ++ +R + +Q R L + + RA
Sbjct: 805 NFKLILVGFERLQAIARSQPLARQYQAMRQRTVQLQALCRGYLVRQQVQA------KRRA 858
Query: 3033 ACLIQAHYRGYKGRQVFLRQKSAALII 3059
+IQAH RG R+ F ++K+ A ++
Sbjct: 859 VVVIQAHARGMAARRNFQQRKANAPLV 885
Score = 47.0 bits (110), Expect = 3e-04
Identities = 35/136 (25%), Positives = 62/136 (45%), Gaps = 6/136 (4%)
Query: 2157 KMQREKYLTILKAVKVLQASFRGVRVRRTLRKMQTAATLIQSNYRRYRQQTYFNKLKKIT 2216
++QR + L +A +Q RG R R+ + + AA +Q+ +R Y + F K+
Sbjct: 756 EVQRSQVLD--RAALSIQKVLRGYRYRKEFLRQRRAAVTLQAWWRGYCNRRNF----KLI 809
Query: 2217 KTVQQRYWAMKERNIQFQRYNKLRHSVIYIQAIFRGKKARRHLKMMHIAATLIQRRFRTL 2276
+R A+ ++Y +R + +QA+ RG R+ ++ A +IQ R +
Sbjct: 810 LVGFERLQAIARSQPLARQYQAMRQRTVQLQALCRGYLVRQQVQAKRRAVVVIQAHARGM 869
Query: 2277 MMRRRFLSLKKTAILI 2292
RR F K A L+
Sbjct: 870 AARRNFQQRKANAPLV 885
Score = 46.6 bits (109), Expect = 4e-04
Identities = 33/121 (27%), Positives = 58/121 (47%), Gaps = 8/121 (6%)
Query: 1776 KAIIVIQNYYHAYKAQVNQRKNFLQVKKAATCLQAAYRGYKVRQLIKQQSIAALKIQSAF 1835
+A + IQ Y+ RK FL+ ++AA LQA +RGY R+ K + ++Q+
Sbjct: 765 RAALSIQKVLRGYR----YRKEFLRQRRAAVTLQAWWRGYCNRRNFKLILVGFERLQAIA 820
Query: 1836 RGYNKRVKYQSVLQSIIKIQRWYRAYKTLHDTRTHFLKTKAAVISLQSAYRGWKVRKQIR 1895
R +YQ++ Q +++Q R Y R + AV+ +Q+ RG R+ +
Sbjct: 821 RSQPLARQYQAMRQRTVQLQALCRGYL----VRQQVQAKRRAVVVIQAHARGMAARRNFQ 876
Query: 1896 R 1896
+
Sbjct: 877 Q 877
Score = 44.3 bits (103), Expect = 0.002
Identities = 39/208 (18%), Positives = 95/208 (45%), Gaps = 16/208 (7%)
Query: 2451 LYQFLHLRKAAITIQSSYRRL-----MVKKKLQEMQRAAVLIQATFRMYRTYI-TFQTWK 2504
+ + +H+RK+ I+ ++ ++ MQ L Q T + ++ T + WK
Sbjct: 680 MMETVHIRKSGFPIRYTFEEFSQRFGVLLPNAMRMQLQGKLRQMTLGITDVWLRTDKDWK 739
Query: 2505 --HASILIQQHYRTYRAAKLQRENYIRQWHSAVVIQAAYKGMKARQLLREKHKASIVIQS 2562
I ++ H T ++QR + + +A+ IQ +G + R+ + +A++ +Q+
Sbjct: 740 AGKTKIFLRDHQDTL--LEVQRSQVLDR--AALSIQKVLRGYRYRKEFLRQRRAAVTLQA 795
Query: 2563 TYRMYRQYCFYQKLQWATKIIQEKYRANKKKQKVFQHNELKKETC-VQAGFQDMNIKKQI 2621
+R YC + + + + + Q+ +++ T +QA + +++Q+
Sbjct: 796 ---WWRGYCNRRNFKLILVGFERLQAIARSQPLARQYQAMRQRTVQLQALCRGYLVRQQV 852
Query: 2622 QEQHQAAIIIQKHCKAFKIRKHYLHLRA 2649
Q + +A ++IQ H + R+++ +A
Sbjct: 853 QAKRRAVVVIQAHARGMAARRNFQQRKA 880
Score = 43.9 bits (102), Expect = 0.003
Identities = 41/146 (28%), Positives = 63/146 (43%), Gaps = 33/146 (22%)
Query: 1701 LRAAALFIQQCYRSKKIAAQKREEYMQMRESCIKLQAFVRGYLVRKQMRLQRKAVISLQS 1760
L AAL IQ+ R + R+E+++ R + + LQA+ RGY R+ +L LQ+
Sbjct: 763 LDRAALSIQKVLRGYRY----RKEFLRQRRAAVTLQAWWRGYCNRRNFKLILVGFERLQA 818
Query: 1761 YFRMRK-ARQYYLKMYKAIIVIQNYYHAYKAQVNQRKNFLQVKKAATCLQAAYRGYKVRQ 1819
R + ARQY +++ LQA RGY VRQ
Sbjct: 819 IARSQPLARQYQ----------------------------AMRQRTVQLQALCRGYLVRQ 850
Query: 1820 LIKQQSIAALKIQSAFRGYNKRVKYQ 1845
++ + A + IQ+ RG R +Q
Sbjct: 851 QVQAKRRAVVVIQAHARGMAARRNFQ 876
Score = 42.7 bits (99), Expect = 0.006
Identities = 35/143 (24%), Positives = 70/143 (48%), Gaps = 16/143 (11%)
Query: 2633 KHCKAFKIRKHYLHLRATVVSIQRRYRKLTAVRTQAVICIQSYYRGFKVRKDIQNMHRAA 2692
K KA K + + T++ +QR + V +A + IQ RG++ RK+ RAA
Sbjct: 736 KDWKAGKTKIFLRDHQDTLLEVQR-----SQVLDRAALSIQKVLRGYRYRKEFLRQRRAA 790
Query: 2693 TLIQSFYRMHRAKVDYETKKTAIVVIQNYYRLYVRVKTE--RKNFLAVQKSVRTIQAAFR 2750
+Q+++R Y ++ +++ + RL +++ + + A+++ +QA R
Sbjct: 791 VTLQAWWR------GYCNRRNFKLILVGFERLQAIARSQPLARQYQAMRQRTVQLQALCR 844
Query: 2751 GMKVRQKLKNVSEEKMAAIVNQS 2773
G VRQ+ V ++ A +V Q+
Sbjct: 845 GYLVRQQ---VQAKRRAVVVIQA 864
Score = 42.4 bits (98), Expect = 0.008
Identities = 37/154 (24%), Positives = 66/154 (42%), Gaps = 17/154 (11%)
Query: 2626 QAAIIIQKHCKAFKIRKHYLHLRATVVSIQRRYRKLTAVRTQAVICI-----QSYYRGFK 2680
+AA+ IQK + ++ RK +L R V++Q +R R +I + Q+ R
Sbjct: 765 RAALSIQKVLRGYRYRKEFLRQRRAAVTLQAWWRGYCNRRNFKLILVGFERLQAIARSQP 824
Query: 2681 VRKDIQNMHRAATLIQSFYRMHRAKVDYETKKTAIVVIQNYYRLYVRVKTERKNF----- 2735
+ + Q M + +Q+ R + + + K+ A+VVIQ + R R+NF
Sbjct: 825 LARQYQAMRQRTVQLQALCRGYLVRQQVQAKRRAVVVIQ----AHARGMAARRNFQQRKA 880
Query: 2736 ---LAVQKSVRTIQAAFRGMKVRQKLKNVSEEKM 2766
L + + Q A K R V++ +M
Sbjct: 881 NAPLVIPAEGQKSQGALPAKKRRSIYDTVTDTEM 914
Score = 42.0 bits (97), Expect = 0.011
Identities = 30/95 (31%), Positives = 48/95 (50%), Gaps = 19/95 (20%)
Query: 3031 RAACLIQAHYRGYKGRQVFLRQKSAALIIQKYIRAREAGKHERI---------------- 3074
RAA IQ RGY+ R+ FLRQ+ AA+ +Q + R ++ ++
Sbjct: 765 RAALSIQKVLRGYRYRKEFLRQRRAAVTLQAWWRGYCNRRNFKLILVGFERLQAIARSQP 824
Query: 3075 ---KYIEFKKSTVILQALVRGWLVRKRFLEQRAKI 3106
+Y ++ TV LQAL RG+LVR++ +R +
Sbjct: 825 LARQYQAMRQRTVQLQALCRGYLVRQQVQAKRRAV 859
Score = 40.8 bits (94), Expect = 0.024
Identities = 33/145 (22%), Positives = 66/145 (45%), Gaps = 4/145 (2%)
Query: 2231 IQFQRYNKLRHSVIYIQAIFRGKKARRHLKMMHIAATLIQRRFRTLMMRRRFLSLKKTAI 2290
++ QR L + + IQ + RG + R+ AA +Q +R RR F +
Sbjct: 755 LEVQRSQVLDRAALSIQKVLRGYRYRKEFLRQRRAAVTLQAWWRGYCNRRNFKLILVGFE 814
Query: 2291 LIQRKYRAHLCTKHHLQFLQVQNAVIKIQSSYRRWMIRKRMREMHRAATFIQSTFRMHRL 2350
+Q R+ + Q+ ++ +++Q+ R +++R++++ RA IQ+ R
Sbjct: 815 RLQAIARSQPLAR---QYQAMRQRTVQLQALCRGYLVRQQVQAKRRAVVVIQAHARGMAA 871
Query: 2351 HMRYQALK-QASVVIQQQYQANRAA 2374
+Q K A +VI + Q ++ A
Sbjct: 872 RRNFQQRKANAPLVIPAEGQKSQGA 896
Score = 39.3 bits (90), Expect = 0.069
Identities = 47/197 (23%), Positives = 84/197 (42%), Gaps = 35/197 (17%)
Query: 1277 WRKYKLKTDLKRHQER----------EKAARIIQLAVINFLAKQRLRKRVNAALVIQKYW 1326
W+ K K L+ HQ+ ++AA IQ + + ++ ++ AA+ +Q +W
Sbjct: 738 WKAGKTKIFLRDHQDTLLEVQRSQVLDRAALSIQKVLRGYRYRKEFLRQRRAAVTLQAWW 797
Query: 1327 RRVLAQR--KLLMLKKEKLEKVQNKAASLIQGYWRRYST-RQRFLKLKYYSIILQSRIRM 1383
R +R KL+++ E+L+ + Q R+Y RQR ++ LQ+ R
Sbjct: 798 RGYCNRRNFKLILVGFERLQAIARS-----QPLARQYQAMRQR-------TVQLQALCRG 845
Query: 1384 IIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQRYEMLKSSTLII-------QSMFRKWKQ 1436
+ + A V IQ H R R+ QQR ++ L+I Q K+
Sbjct: 846 YLVRQQVQAKRRAVVVIQAHARGMAARRNFQQR---KANAPLVIPAEGQKSQGALPAKKR 902
Query: 1437 RKMQSQVKATVILQRAF 1453
R + V T ++++ F
Sbjct: 903 RSIYDTVTDTEMVEKVF 919
Score = 37.0 bits (84), Expect = 0.34
Identities = 39/193 (20%), Positives = 83/193 (43%), Gaps = 32/193 (16%)
Query: 1425 LIIQSMFRKWKQRKMQSQVKATVILQRAFREWHLRKQAKEENSAIIIQSWYRMHKELRKY 1484
L+ +M + + + Q + T + R ++W K + I ++ E+++
Sbjct: 707 LLPNAMRMQLQGKLRQMTLGITDVWLRTDKDW------KAGKTKIFLRDHQDTLLEVQRS 760
Query: 1485 IYIRSCVVIIQKRFRCFQAQKLYKRRKESILTIQKYYKAYLKGKIERTNYLQKRAAAIQL 1544
+ + IQK R ++ +K + R++ + +T+Q +++ Y R N+ +L
Sbjct: 761 QVLDRAALSIQKVLRGYRYRKEFLRQRRAAVTLQAWWRGY----CNRRNFKLILVGFERL 816
Query: 1545 QAAFRRLKAHNLCRQIRAACVIQSYWRMRQDRVRFLNLKKTIIKFQAHVRKHQQRQKYKK 1604
QA R + L RQ +A +++ ++ QA R + RQ+ +
Sbjct: 817 QAIAR---SQPLARQYQA-------------------MRQRTVQLQALCRGYLVRQQVQA 854
Query: 1605 MKKAAVIIQTHFR 1617
++A V+IQ H R
Sbjct: 855 KRRAVVVIQAHAR 867
Score = 35.8 bits (81), Expect = 0.76
Identities = 30/140 (21%), Positives = 60/140 (42%), Gaps = 26/140 (18%)
Query: 2976 AILKAVKIIQGCFYTKLERTRFLNVRASAIIIQRKWRAILPAK------IAHEHFLMIKR 3029
A L K+++G Y K FL R +A+ +Q WR + + E I R
Sbjct: 766 AALSIQKVLRGYRYRK----EFLRQRRAAVTLQAWWRGYCNRRNFKLILVGFERLQAIAR 821
Query: 3030 HRAACLIQAHYRGYKGRQVFLRQKSAALIIQKYIRAREAGKHERIKYIEFKKSTVILQAL 3089
+ + Y+ + R V L+ ++++ ++A+ +++ V++QA
Sbjct: 822 SQP---LARQYQAMRQRTVQLQALCRGYLVRQQVQAK-------------RRAVVVIQAH 865
Query: 3090 VRGWLVRKRFLEQRAKIRLL 3109
RG R+ F +++A L+
Sbjct: 866 ARGMAARRNFQQRKANAPLV 885
Score = 33.5 bits (75), Expect = 3.8
Identities = 25/117 (21%), Positives = 52/117 (44%), Gaps = 7/117 (5%)
Query: 3121 AVRIQRAYKLYLAVKNANKQVNSVICIQRWFRARLQEKRF------IQKYHSIKKIEHEG 3174
A+ IQ+ + Y K +Q + + +Q W+R + F ++ +I + +
Sbjct: 767 ALSIQKVLRGYRYRKEFLRQRRAAVTLQAWWRGYCNRRNFKLILVGFERLQAIARSQPLA 826
Query: 3175 QECLSQRNRAASVIQKAVRHFLLRKKQEKFTSGIIKIQALWRGYSWRKKNDCTKIKA 3231
++ + R R +Q R +L+R++ + ++ IQA RG + R+ K A
Sbjct: 827 RQYQAMRQRTVQ-LQALCRGYLVRQQVQAKRRAVVVIQAHARGMAARRNFQQRKANA 882
Score = 32.3 bits (72), Expect = 8.4
Identities = 30/128 (23%), Positives = 56/128 (43%), Gaps = 28/128 (21%)
Query: 1345 KVQNKAASLIQGYWRRYSTRQRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHW 1404
+V ++AA IQ R Y R+ FL+ + A VT+Q W
Sbjct: 761 QVLDRAALSIQKVLRGYRYRKEFLRQRR-----------------------AAVTLQAWW 797
Query: 1405 RAYLRRKQDQQRYEMLKSSTLIIQSMFRKWK-QRKMQSQVKATVILQRAFREWHLRKQAK 1463
R Y R+ ++++ +Q++ R R+ Q+ + TV LQ R + +R+Q +
Sbjct: 798 RGYCNRR----NFKLILVGFERLQAIARSQPLARQYQAMRQRTVQLQALCRGYLVRQQVQ 853
Query: 1464 EENSAIII 1471
+ A+++
Sbjct: 854 AKRRAVVV 861
>gi|169218211 PREDICTED: similar to plectin 1, partial [Homo sapiens]
Length = 1369
Score = 62.4 bits (150), Expect = 8e-09
Identities = 76/321 (23%), Positives = 128/321 (39%), Gaps = 102/321 (31%)
Query: 965 VTNLAVDLQCGVRLVRTMELLTQNWDLSKKLRIPAISRLQKMHNVDIVLQVLKSRGIELS 1024
+++L DL+ G L+ +E+L+ + +K R+ R K+ NV I L L+ R ++L
Sbjct: 196 ISDLYEDLRDGHNLISLLEVLSGDSLPREKGRM----RFHKLQNVQIALDYLRHRQVKLV 251
Query: 1025 DEHGNTILSKDIVDRHREKTLRLLWKIAFAFQV-DISLNLDQLKEEIAFLKHTKSIKKTI 1083
+ I + DI D + + TL L+W I FQ+ DI +
Sbjct: 252 N-----IRNDDIADGNPKLTLGLIWTIILHFQISDIQV---------------------- 284
Query: 1084 SLLSCHSDDLINKKKGKRDSGSFEQYSENIKLLMDWVNAVCAFYNKKVENFTVSFSDGRV 1143
SG E + KLL+ V + + +NFT S+ DGR+
Sbjct: 285 -------------------SGQSEDMTAKEKLLLWSQRMVEGYQGLRCDNFTSSWRDGRL 325
Query: 1144 LCYLIHHYHPCYVPFDAICQRTTQTVECTQTGSVVLNSSSESDDSSLDMSLKAFDHENTS 1203
+IH + P + + + ++T
Sbjct: 326 FNAIIHRHKPLLIDMNKVYRQTN------------------------------------- 348
Query: 1204 ELYKELLENEKKNFHLVRSAVRDLGGIPAMINHSDMSNTIPDEKVVITYLSFL---CARL 1260
LEN + F + A RDL G+ +++ D+ PDEK +ITY+S L R+
Sbjct: 349 ------LENLDQAFSV---AERDL-GVTRLLDPEDVDVPQPDEKSIITYVSSLYDAMPRV 398
Query: 1261 LDLRKEIRAARLIQTTWRKYK 1281
D++ +RA L Q W++Y+
Sbjct: 399 PDVQDGVRANEL-QLRWQEYR 418
>gi|54112401 calmodulin-binding transcription activator 1 [Homo
sapiens]
Length = 1673
Score = 62.4 bits (150), Expect = 8e-09
Identities = 45/157 (28%), Positives = 75/157 (47%), Gaps = 31/157 (19%)
Query: 2523 QRENYIRQWHSAVVIQAAYKGMKARQLLREKHKASIVIQSTYRMYRQYCFYQKLQWATKI 2582
QRE Y +A ++Q A++ K R L ++ A+ VIQ YR Y+QY Y+K+ A +
Sbjct: 1521 QRELY----EAARLVQTAFRKYKGRPLREQQEVAAAVIQRCYRKYKQYALYKKMTQAAIL 1576
Query: 2583 IQEKYRANKKKQKVFQHNELKKETCVQAGFQDMNIKKQIQEQHQAAIIIQKHCKAFKIRK 2642
IQ K+R+ + +K+ Q+ +AA++IQK+ +++K
Sbjct: 1577 IQSKFRSYYE-------------------------QKKFQQSRRAAVLIQKYYRSYKKCG 1611
Query: 2643 HYLHLRATVVSIQRRYRK--LTAVRTQAVICIQSYYR 2677
R T V +Q++ R LT + QA I + R
Sbjct: 1612 KRRQARRTAVIVQQKLRSSLLTKKQDQAARKIMRFLR 1648
Score = 60.8 bits (146), Expect = 2e-08
Identities = 44/142 (30%), Positives = 73/142 (51%), Gaps = 15/142 (10%)
Query: 1773 KMYKAIIVIQNYYHAYKAQVNQRKNFLQVKKAATCLQAAYRGYKVRQLIKQQSIAALKIQ 1832
++Y+A ++Q + YK + + Q + AA +Q YR YK L K+ + AA+ IQ
Sbjct: 1523 ELYEAARLVQTAFRKYKGRPLRE----QQEVAAAVIQRCYRKYKQYALYKKMTQAAILIQ 1578
Query: 1833 SAFRGYNKRVKYQSVLQSIIKIQRWYRAYKTLHDTRTHFLKTKAAVISLQSAYRGWKVRK 1892
S FR Y ++ K+Q ++ + IQ++YR+YK R + AVI Q K+R
Sbjct: 1579 SKFRSYYEQKKFQQSRRAAVLIQKYYRSYKKCGKRRQ---ARRTAVIVQQ------KLRS 1629
Query: 1893 QI--RREHQAALKIQSAFRMAK 1912
+ +++ QAA KI R +
Sbjct: 1630 SLLTKKQDQAARKIMRFLRRCR 1651
Score = 60.1 bits (144), Expect = 4e-08
Identities = 40/126 (31%), Positives = 67/126 (53%), Gaps = 5/126 (3%)
Query: 1962 TLRRQLQRQ-HKCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYRAYSIGREQNHLYLKT 2020
TL QR+ ++ A ++Q+ +R + + + + AA +IQ+ YR Y +Q LY K
Sbjct: 1515 TLSDHEQRELYEAARLVQTAFRKYKGRPLREQQEVAAAVIQRCYRKY----KQYALYKKM 1570
Query: 2021 KAAVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGI 2080
A + +QS +R +K+ + +AAV IQ YR+YK K R +A+I+Q+ R
Sbjct: 1571 TQAAILIQSKFRSYYEQKKFQQSRRAAVLIQKYYRSYKKCGKRRQARRTAVIVQQKLRSS 1630
Query: 2081 KITNHQ 2086
+T Q
Sbjct: 1631 LLTKKQ 1636
Score = 57.8 bits (138), Expect = 2e-07
Identities = 44/146 (30%), Positives = 74/146 (50%), Gaps = 13/146 (8%)
Query: 2405 KSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKHKLYQ-FLHLRKAAIT 2463
+ ++ +A L+Q+ FR R + A +QR YR K+K Y + + +AAI
Sbjct: 1522 RELYEAARLVQTAFRKYKGRPLREQQEVAAAVIQRCYR-----KYKQYALYKKMTQAAIL 1576
Query: 2464 IQSSYRRLMVKKKLQEMQRAAVLIQATFRMYRTYITFQTWKHASILIQQHYRTYRAAKLQ 2523
IQS +R +KK Q+ +RAAVLIQ +R Y+ + + ++++QQ R+ K Q
Sbjct: 1577 IQSKFRSYYEQKKFQQSRRAAVLIQKYYRSYKKCGKRRQARRTAVIVQQKLRSSLLTKKQ 1636
Query: 2524 RE------NYIRQW-HSAVVIQAAYK 2542
+ ++R+ HS +V YK
Sbjct: 1637 DQAARKIMRFLRRCRHSPLVDHRLYK 1662
Score = 57.0 bits (136), Expect = 3e-07
Identities = 37/137 (27%), Positives = 68/137 (49%), Gaps = 26/137 (18%)
Query: 1413 DQQRYEMLKSSTLIIQSMFRKWKQRKMQSQVKATVILQRAFREWHLRKQAKEENSAIIIQ 1472
D ++ E+ +++ L+ Q+ FRK+K R ++ Q +E +A +IQ
Sbjct: 1518 DHEQRELYEAARLV-QTAFRKYKGRPLREQ---------------------QEVAAAVIQ 1555
Query: 1473 SWYRMHKELRKYIYIRSCVVIIQKRFRCFQAQKLYKRRKESILTIQKYYKAYLKGKIERT 1532
YR +K+ Y + ++IQ +FR + QK +++ + + + IQKYY++Y K R
Sbjct: 1556 RCYRKYKQYALYKKMTQAAILIQSKFRSYYEQKKFQQSRRAAVLIQKYYRSYKKCGKRR- 1614
Query: 1533 NYLQKRAAAIQLQAAFR 1549
Q R A+ +Q R
Sbjct: 1615 ---QARRTAVIVQQKLR 1628
Score = 56.6 bits (135), Expect = 4e-07
Identities = 44/167 (26%), Positives = 77/167 (46%), Gaps = 34/167 (20%)
Query: 1800 QVKKAATCLQAAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRVKYQSVLQSIIKIQRWYR 1859
++ +AA +Q A+R YK R L +QQ +AA IQ +R Y + Y+ + Q
Sbjct: 1523 ELYEAARLVQTAFRKYKGRPLREQQEVAAAVIQRCYRKYKQYALYKKMTQ---------- 1572
Query: 1860 AYKTLHDTRTHFLKTKAAVISLQSAYRGWKVRKQIRREHQAALKIQSAFRMAKAQKQFRL 1919
A I +QS +R + +K+ ++ +AA+ IQ +R K + R
Sbjct: 1573 -----------------AAILIQSKFRSYYEQKKFQQSRRAAVLIQKYYRSYKKCGKRRQ 1615
Query: 1920 FKTAALVIQQNFRAWTAGRKQ------CMEYI-ELRHAVLVLQSMWK 1959
+ A+++QQ R+ +KQ M ++ RH+ LV ++K
Sbjct: 1616 ARRTAVIVQQKLRSSLLTKKQDQAARKIMRFLRRCRHSPLVDHRLYK 1662
Score = 56.2 bits (134), Expect = 5e-07
Identities = 32/120 (26%), Positives = 69/120 (57%), Gaps = 4/120 (3%)
Query: 1895 RREHQAALKIQSAFRMAKAQKQFRLFKTAALVIQQNFRAWTAGRKQCMEYIELRHAVLVL 1954
R ++AA +Q+AFR K + + AA VIQ+ +R + KQ Y ++ A +++
Sbjct: 1522 RELYEAARLVQTAFRKYKGRPLREQQEVAAAVIQRCYRKY----KQYALYKKMTQAAILI 1577
Query: 1955 QSMWKGKTLRRQLQRQHKCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYRAYSIGREQN 2014
QS ++ +++ Q+ + A++IQ YYR + + K + ++ A+++Q+ R+ + ++Q+
Sbjct: 1578 QSKFRSYYEQKKFQQSRRAAVLIQKYYRSYKKCGKRRQARRTAVIVQQKLRSSLLTKKQD 1637
Score = 55.5 bits (132), Expect = 9e-07
Identities = 32/117 (27%), Positives = 62/117 (52%), Gaps = 4/117 (3%)
Query: 2187 RKMQTAATLIQSNYRRYRQQTYFNKLKKITKTVQQRYWAMKERNIQFQRYNKLRHSVIYI 2246
R++ AA L+Q+ +R+Y+ + + + +Q+ Y K Q+ Y K+ + I I
Sbjct: 1522 RELYEAARLVQTAFRKYKGRPLREQQEVAAAVIQRCYRKYK----QYALYKKMTQAAILI 1577
Query: 2247 QAIFRGKKARRHLKMMHIAATLIQRRFRTLMMRRRFLSLKKTAILIQRKYRAHLCTK 2303
Q+ FR ++ + AA LIQ+ +R+ + ++TA+++Q+K R+ L TK
Sbjct: 1578 QSKFRSYYEQKKFQQSRRAAVLIQKYYRSYKKCGKRRQARRTAVIVQQKLRSSLLTK 1634
Score = 55.5 bits (132), Expect = 9e-07
Identities = 36/111 (32%), Positives = 59/111 (53%), Gaps = 8/111 (7%)
Query: 1995 KAALLIQKYYRAYSIGREQNHLYLKTKAAVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKY 2054
+AA L+Q +R Y GR L + + A +Q YR K K +AA+ IQSK+
Sbjct: 1526 EAARLVQTAFRKYK-GRP---LREQQEVAAAVIQRCYRKYKQYALYKKMTQAAILIQSKF 1581
Query: 2055 RAYKTKKKYATYRASAIIIQRWYRGIKITNHQHKEYLNLKKTAIKIQSVYR 2105
R+Y +KK+ R +A++IQ++YR K + + ++TA+ +Q R
Sbjct: 1582 RSYYEQKKFQQSRRAAVLIQKYYRSYKKCGKRRQ----ARRTAVIVQQKLR 1628
Score = 55.1 bits (131), Expect = 1e-06
Identities = 38/144 (26%), Positives = 68/144 (47%), Gaps = 14/144 (9%)
Query: 2340 FIQSTFRMHRLHMRYQALKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAFRGMK 2399
F Q T H Y+A + ++Q ++ + L+ Q Q +A ++Q +R K
Sbjct: 1511 FAQLTLSDHEQRELYEAAR----LVQTAFRKYKGRPLREQ----QEVAAAVIQRCYRKYK 1562
Query: 2400 TRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRA-TICAKHKLYQFLHLR 2458
K M +A LIQS+FRS +++F ++A + +Q+ YR+ C K + R
Sbjct: 1563 QYALYKKMTQAAILIQSKFRSYYEQKKFQQSRRAAVLIQKYYRSYKKCGKRR-----QAR 1617
Query: 2459 KAAITIQSSYRRLMVKKKLQEMQR 2482
+ A+ +Q R ++ KK + R
Sbjct: 1618 RTAVIVQQKLRSSLLTKKQDQAAR 1641
Score = 54.7 bits (130), Expect = 2e-06
Identities = 38/136 (27%), Positives = 72/136 (52%), Gaps = 10/136 (7%)
Query: 2262 MHIAATLIQRRFRTLMMRRRFLSLKKTAILIQRKYRAHLCTKHHLQFLQVQNAVIKIQSS 2321
++ AA L+Q FR R + A +IQR YR + K + + ++ A I IQS
Sbjct: 1524 LYEAARLVQTAFRKYKGRPLREQQEVAAAVIQRCYRKY---KQYALYKKMTQAAILIQSK 1580
Query: 2322 YRRWMIRKRMREMHRAATFIQSTFRMHRLHMRYQALKQASVVIQQQYQANRAAKLQRQ-- 2379
+R + +K+ ++ RAA IQ +R ++ + + ++ +V++QQ+ +++ K Q Q
Sbjct: 1581 FRSYYEQKKFQQSRRAAVLIQKYYRSYKKCGKRRQARRTAVIVQQKLRSSLLTKKQDQAA 1640
Query: 2380 ----HYLRQ-RHSAVI 2390
+LR+ RHS ++
Sbjct: 1641 RKIMRFLRRCRHSPLV 1656
Score = 53.1 bits (126), Expect = 5e-06
Identities = 33/131 (25%), Positives = 64/131 (48%), Gaps = 4/131 (3%)
Query: 2041 KDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKITNHQHKEYLNLKKTAIKI 2100
++ +AA +Q+ +R YK + +A +IQR YR K Q+ Y + + AI I
Sbjct: 1522 RELYEAARLVQTAFRKYKGRPLREQQEVAAAVIQRCYRKYK----QYALYKKMTQAAILI 1577
Query: 2101 QSVYRGIRVRRHIQHMHRAATFIKAMFKMHQSRISYHTMRKAAIVIQVRCRAYYQGKMQR 2160
QS +R ++ Q RAA I+ ++ ++ R+ A+++Q + R+ K Q
Sbjct: 1578 QSKFRSYYEQKKFQQSRRAAVLIQKYYRSYKKCGKRRQARRTAVIVQQKLRSSLLTKKQD 1637
Query: 2161 EKYLTILKAVK 2171
+ I++ ++
Sbjct: 1638 QAARKIMRFLR 1648
Score = 52.0 bits (123), Expect = 1e-05
Identities = 43/147 (29%), Positives = 65/147 (44%), Gaps = 8/147 (5%)
Query: 2622 QEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQRRYRK-----LTAVRTQAVICIQSYY 2676
+E ++AA ++Q + +K R IQR YRK L TQA I IQS +
Sbjct: 1522 RELYEAARLVQTAFRKYKGRPLREQQEVAAAVIQRCYRKYKQYALYKKMTQAAILIQSKF 1581
Query: 2677 RGFKVRKDIQNMHRAATLIQSFYRMHRAKVDYETKKTAIVVIQNYYRLYVRVKTERKNFL 2736
R + +K Q RAA LIQ +YR ++ + V++Q R + K K
Sbjct: 1582 RSYYEQKKFQQSRRAAVLIQKYYRSYKKCGKRRQARRTAVIVQQKLRSSLLTK---KQDQ 1638
Query: 2737 AVQKSVRTIQAAFRGMKVRQKLKNVSE 2763
A +K +R ++ V +L SE
Sbjct: 1639 AARKIMRFLRRCRHSPLVDHRLYKRSE 1665
Score = 51.2 bits (121), Expect = 2e-05
Identities = 35/112 (31%), Positives = 59/112 (52%), Gaps = 4/112 (3%)
Query: 1540 AAIQLQAAFRRLKAHNLCRQIR-AACVIQSYWRMRQDRVRFLNLKKTIIKFQAHVRKHQQ 1598
AA +Q AFR+ K L Q AA VIQ +R + + + + I Q+ R + +
Sbjct: 1527 AARLVQTAFRKYKGRPLREQQEVAAAVIQRCYRKYKQYALYKKMTQAAILIQSKFRSYYE 1586
Query: 1599 RQKYKKMKKAAVIIQTHFRAYIFAMKVLASYQKTRSAVIVLQSAYRGMQARK 1650
++K+++ ++AAV+IQ ++R+Y K Q R+AVIV Q + +K
Sbjct: 1587 QKKFQQSRRAAVLIQKYYRSY---KKCGKRRQARRTAVIVQQKLRSSLLTKK 1635
Score = 50.8 bits (120), Expect = 2e-05
Identities = 40/153 (26%), Positives = 73/153 (47%), Gaps = 13/153 (8%)
Query: 1230 IPAMINHSDMSNTIPDEKVVITYLSFLCARLLDLRKEIRAARLIQTTWRKYKLKTDLKRH 1289
+P+ + S+ + EKV + + + R+ AARL+QT +RKYK +
Sbjct: 1489 LPSAADWSEFLSASTSEKVENEFAQLTLSDH-EQRELYEAARLVQTAFRKYKGR---PLR 1544
Query: 1290 QEREKAARIIQLAVINFLAKQRLRKRVNAALVIQKYWRRVLAQRKLLMLKKEKLEKVQNK 1349
+++E AA +IQ + +K AA++IQ +R Q+K + +
Sbjct: 1545 EQQEVAAAVIQRCYRKYKQYALYKKMTQAAILIQSKFRSYYEQKKF---------QQSRR 1595
Query: 1350 AASLIQGYWRRYSTRQRFLKLKYYSIILQSRIR 1382
AA LIQ Y+R Y + + + ++I+Q ++R
Sbjct: 1596 AAVLIQKYYRSYKKCGKRRQARRTAVIVQQKLR 1628
Score = 50.1 bits (118), Expect = 4e-05
Identities = 33/109 (30%), Positives = 60/109 (55%), Gaps = 7/109 (6%)
Query: 2460 AAITIQSSYRRLMVKKKLQEMQRAAVLIQATFRMYRTYITFQTWKHASILIQQHYRTYRA 2519
AA IQ YR+ ++M +AA+LIQ+ FR Y FQ + A++LIQ++YR+Y+
Sbjct: 1550 AAAVIQRCYRKYKQYALYKKMTQAAILIQSKFRSYYEQKKFQQSRRAAVLIQKYYRSYKK 1609
Query: 2520 AKLQRENYIRQWHSAVVIQAAYKGMKARQLLREKHKASIVIQSTYRMYR 2568
+R+ +AV++Q + +++ L +++ +A+ I R R
Sbjct: 1610 CGKRRQ----ARRTAVIVQ---QKLRSSLLTKKQDQAARKIMRFLRRCR 1651
Score = 49.7 bits (117), Expect = 5e-05
Identities = 49/165 (29%), Positives = 79/165 (47%), Gaps = 36/165 (21%)
Query: 1590 QAHVRKHQQRQKYKKMKKAAVIIQTHFRAYIFAMKVLASYQKTRSAVIVLQSAYRGMQAR 1649
Q + H+QR+ Y+ AA ++QT FR Y + L Q+ +AVI Q YR +
Sbjct: 1513 QLTLSDHEQRELYE----AARLVQTAFRKY--KGRPLREQQEVAAAVI--QRCYRKYKQY 1564
Query: 1650 KMYIHILTSVIKIQSYYRAYVSKKEFLSLKNATIKLQSTVKMKQTRKQYLHLRAAALFIQ 1709
+Y + + I IQS +R+Y +K+F +Q+R+ AA+ IQ
Sbjct: 1565 ALYKKMTQAAILIQSKFRSYYEQKKF----------------QQSRR-------AAVLIQ 1601
Query: 1710 QCYRSKKIAAQKREEYMQMRESCIKLQAFVR-GYLVRKQMRLQRK 1753
+ YRS K ++R Q R + + +Q +R L +KQ + RK
Sbjct: 1602 KYYRSYKKCGKRR----QARRTAVIVQQKLRSSLLTKKQDQAARK 1642
Score = 49.3 bits (116), Expect = 7e-05
Identities = 31/125 (24%), Positives = 69/125 (55%), Gaps = 9/125 (7%)
Query: 1400 IQRHWRAYLRRKQDQQRYEMLKSSTLIIQSMFRKWKQRKM-QSQVKATVILQRAFREWHL 1458
+Q +R Y R +Q+ + + +IQ +RK+KQ + + +A +++Q FR ++
Sbjct: 1531 VQTAFRKYKGRPLREQQ----EVAAAVIQRCYRKYKQYALYKKMTQAAILIQSKFRSYYE 1586
Query: 1459 RKQAKE-ENSAIIIQSWYRMHKELRKYIYIRSCVVIIQKRFRCFQAQKLYKRRKESILTI 1517
+K+ ++ +A++IQ +YR +K+ K R VI+Q++ R + L K++ ++ I
Sbjct: 1587 QKKFQQSRRAAVLIQKYYRSYKKCGKRRQARRTAVIVQQKLR---SSLLTKKQDQAARKI 1643
Query: 1518 QKYYK 1522
++ +
Sbjct: 1644 MRFLR 1648
Score = 47.0 bits (110), Expect = 3e-04
Identities = 37/140 (26%), Positives = 72/140 (51%), Gaps = 14/140 (10%)
Query: 2973 EYLAILKAVKIIQGCFYTKLERTRFLNVRASAIIIQRKWRAILPAKIAHEHFLMIKRHRA 3032
E + +A +++Q F R +A +IQR +R ++ L K +A
Sbjct: 1520 EQRELYEAARLVQTAFRKYKGRPLREQQEVAAAVIQRCYRKY------KQYALYKKMTQA 1573
Query: 3033 ACLIQAHYRGYKGRQVFLRQKSAALIIQKYIRA-REAGKHERIKYIEFKKSTVILQALVR 3091
A LIQ+ +R Y ++ F + + AA++IQKY R+ ++ GK + +++ VI+Q +R
Sbjct: 1574 AILIQSKFRSYYEQKKFQQSRRAAVLIQKYYRSYKKCGKRR-----QARRTAVIVQQKLR 1628
Query: 3092 GWLVRKRFLEQRAKIRLLHF 3111
L+ K+ + +A +++ F
Sbjct: 1629 SSLLTKK--QDQAARKIMRF 1646
Score = 46.6 bits (109), Expect = 4e-04
Identities = 33/128 (25%), Positives = 64/128 (50%), Gaps = 5/128 (3%)
Query: 2096 TAIKIQSVYRGIRVRRHIQH-MHRAATFIKAMFKMHQSRISYHTMRKAAIVIQVRCRAYY 2154
T+ K+++ + + + H Q ++ AA ++ F+ ++ R AA VIQ RC Y
Sbjct: 1503 TSEKVENEFAQLTLSDHEQRELYEAARLVQTAFRKYKGRPLREQQEVAAAVIQ-RCYRKY 1561
Query: 2155 QGKMQREKYLTILKAVKVLQASFRGVRVRRTLRKMQTAATLIQSNYRRYRQQTYFNKLKK 2214
+ Q Y + +A ++Q+ FR ++ ++ + AA LIQ YR Y++ + ++
Sbjct: 1562 K---QYALYKKMTQAAILIQSKFRSYYEQKKFQQSRRAAVLIQKYYRSYKKCGKRRQARR 1618
Query: 2215 ITKTVQQR 2222
VQQ+
Sbjct: 1619 TAVIVQQK 1626
Score = 45.1 bits (105), Expect = 0.001
Identities = 29/129 (22%), Positives = 64/129 (49%), Gaps = 7/129 (5%)
Query: 2073 IQRWYRGIKITNHQHKEYLNLKKTAIKIQSVYRGIRVRRHIQHMHRAATFIKAMFKMHQS 2132
++ + + +++H+ +E L + A +Q+ +R + R + AA I+ ++ ++
Sbjct: 1507 VENEFAQLTLSDHEQRE---LYEAARLVQTAFRKYKGRPLREQQEVAAAVIQRCYRKYKQ 1563
Query: 2133 RISYHTMRKAAIVIQVRCRAYYQGKMQREKYLTILKAVKVLQASFRGVRVRRTLRKMQTA 2192
Y M +AAI+IQ + R+YY+ K K+ +A ++Q +R + R+ +
Sbjct: 1564 YALYKKMTQAAILIQSKFRSYYEQK----KFQQSRRAAVLIQKYYRSYKKCGKRRQARRT 1619
Query: 2193 ATLIQSNYR 2201
A ++Q R
Sbjct: 1620 AVIVQQKLR 1628
Score = 45.1 bits (105), Expect = 0.001
Identities = 31/113 (27%), Positives = 58/113 (51%), Gaps = 8/113 (7%)
Query: 1854 IQRWYRAYKTLHDTRTHFLKTKAAVISLQSAYRGWKVRKQIRREHQAALKIQSAFRMAKA 1913
+Q +R YK R + + A +Q YR +K ++ QAA+ IQS FR
Sbjct: 1531 VQTAFRKYKG----RPLREQQEVAAAVIQRCYRKYKQYALYKKMTQAAILIQSKFRSYYE 1586
Query: 1914 QKQFRLFKTAALVIQQNFRAWTAGRKQCMEYIELRHAVLVLQSMWKGKTLRRQ 1966
QK+F+ + AA++IQ+ +R++ K+C + + R +++Q + L ++
Sbjct: 1587 QKKFQQSRRAAVLIQKYYRSY----KKCGKRRQARRTAVIVQQKLRSSLLTKK 1635
Score = 43.9 bits (102), Expect = 0.003
Identities = 34/149 (22%), Positives = 69/149 (46%), Gaps = 6/149 (4%)
Query: 2846 FLQMAVYRRRFVQQKRAAITLQHYFRTWQTRKQFLLYRKAAVVLQNHYRAFLSAKHQRQV 2905
F Q+ + + AA +Q FR ++ R AA V+Q YR + Q +
Sbjct: 1511 FAQLTLSDHEQRELYEAARLVQTAFRKYKGRPLREQQEVAAAVIQRCYRKY----KQYAL 1566
Query: 2906 YLQIRSSVIIIQARSKGFIQKRKFQEIKNSTIKIQAMWRRYR--AKKYLCKVKAACKIQA 2963
Y ++ + I+IQ++ + + +++KFQ+ + + + IQ +R Y+ K+ + A Q
Sbjct: 1567 YKKMTQAAILIQSKFRSYYEQKKFQQSRRAAVLIQKYYRSYKKCGKRRQARRTAVIVQQK 1626
Query: 2964 WYRCWRAHKEYLAILKAVKIIQGCFYTKL 2992
K+ A K ++ ++ C ++ L
Sbjct: 1627 LRSSLLTKKQDQAARKIMRFLRRCRHSPL 1655
Score = 43.9 bits (102), Expect = 0.003
Identities = 33/142 (23%), Positives = 66/142 (46%), Gaps = 13/142 (9%)
Query: 1307 LAKQRLRKRVNAALVIQKYWRRVLAQRKLLMLKKEKLEKVQNKAASLIQGYWRRYSTRQR 1366
L+ R+ AA ++Q +R+ K L + Q AA++IQ +R+Y
Sbjct: 1516 LSDHEQRELYEAARLVQTAFRKY---------KGRPLREQQEVAAAVIQRCYRKYKQYAL 1566
Query: 1367 FLKLKYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQRYEMLKSSTLI 1426
+ K+ +I++QS+ R +++ A V IQ+++R+Y + + +Q + + +I
Sbjct: 1567 YKKMTQAAILIQSKFRSYYEQKKFQQSRRAAVLIQKYYRSYKKCGKRRQ----ARRTAVI 1622
Query: 1427 IQSMFRKWKQRKMQSQVKATVI 1448
+Q R K Q Q ++
Sbjct: 1623 VQQKLRSSLLTKKQDQAARKIM 1644
Score = 42.7 bits (99), Expect = 0.006
Identities = 39/149 (26%), Positives = 68/149 (45%), Gaps = 9/149 (6%)
Query: 2762 SEEKMAAIVNQSALCCYRSKTQYEAVQSEGVMIQEWYKASGLACSQEAEYHSQSRAAVTI 2821
+ EK+ Q L + + YEA + ++ YK L QE AA I
Sbjct: 1503 TSEKVENEFAQLTLSDHEQRELYEAARLVQTAFRK-YKGRPLREQQEV-------AAAVI 1554
Query: 2822 QKAFCRMVTRKLETQKC-AALRIQFFLQMAVYRRRFVQQKRAAITLQHYFRTWQTRKQFL 2880
Q+ + + L + AA+ IQ + +++F Q +RAA+ +Q Y+R+++ +
Sbjct: 1555 QRCYRKYKQYALYKKMTQAAILIQSKFRSYYEQKKFQQSRRAAVLIQKYYRSYKKCGKRR 1614
Query: 2881 LYRKAAVVLQNHYRAFLSAKHQRQVYLQI 2909
R+ AV++Q R+ L K Q Q +I
Sbjct: 1615 QARRTAVIVQQKLRSSLLTKKQDQAARKI 1643
Score = 42.4 bits (98), Expect = 0.008
Identities = 29/95 (30%), Positives = 48/95 (50%), Gaps = 5/95 (5%)
Query: 3121 AVRIQRAYKLYLAVKNANKQVNSVICIQRWFRARLQEKRFIQKYHS---IKKIEHEGQEC 3177
A IQR Y+ Y K + I IQ FR+ ++K+F Q + I+K ++C
Sbjct: 1551 AAVIQRCYRKYKQYALYKKMTQAAILIQSKFRSYYEQKKFQQSRRAAVLIQKYYRSYKKC 1610
Query: 3178 LSQR--NRAASVIQKAVRHFLLRKKQEKFTSGIIK 3210
+R R A ++Q+ +R LL KKQ++ I++
Sbjct: 1611 GKRRQARRTAVIVQQKLRSSLLTKKQDQAARKIMR 1645
Score = 42.0 bits (97), Expect = 0.011
Identities = 29/113 (25%), Positives = 52/113 (46%), Gaps = 4/113 (3%)
Query: 1670 VSKKEFLSLKNATIKLQSTVKMKQTRKQYLHLRAAALFIQQCYRSKKIAAQKREEYMQMR 1729
+S E L A +Q+ + + R AA IQ+CYR K A Y +M
Sbjct: 1516 LSDHEQRELYEAARLVQTAFRKYKGRPLREQQEVAAAVIQRCYRKYKQYAL----YKKMT 1571
Query: 1730 ESCIKLQAFVRGYLVRKQMRLQRKAVISLQSYFRMRKARQYYLKMYKAIIVIQ 1782
++ I +Q+ R Y +K+ + R+A + +Q Y+R K + + +++Q
Sbjct: 1572 QAAILIQSKFRSYYEQKKFQQSRRAAVLIQKYYRSYKKCGKRRQARRTAVIVQ 1624
Score = 41.2 bits (95), Expect = 0.018
Identities = 44/166 (26%), Positives = 71/166 (42%), Gaps = 17/166 (10%)
Query: 1674 EFLSLKNATIKLQSTVKMKQTRKQYLHLRAAALFIQQCYRSKKIAAQKREEYMQMRESCI 1733
EFLS + ++ + + L AA +Q +R K + E ++ + I
Sbjct: 1497 EFLSASTSEKVENEFAQLTLSDHEQRELYEAARLVQTAFRKYK--GRPLREQQEVAAAVI 1554
Query: 1734 KLQAFVRGYLVRKQMRLQRK---AVISLQSYFRMRKARQYYLKMYKAIIVIQNYYHAYKA 1790
+ R Y KQ L +K A I +QS FR ++ + + +A ++IQ YY +YK
Sbjct: 1555 Q-----RCYRKYKQYALYKKMTQAAILIQSKFRSYYEQKKFQQSRRAAVLIQKYYRSYKK 1609
Query: 1791 QVNQRKNFLQVKKAATCLQAAYRGYKVRQLIKQQSIAALKIQSAFR 1836
+R Q ++ A +Q R L K+Q AA KI R
Sbjct: 1610 CGKRR----QARRTAVIVQQKLRS---SLLTKKQDQAARKIMRFLR 1648
Score = 39.3 bits (90), Expect = 0.069
Identities = 24/83 (28%), Positives = 45/83 (54%), Gaps = 6/83 (7%)
Query: 1396 ATVTIQRHWRAYLRRKQDQQRYEMLKSSTLIIQSMFRKW-KQRKMQSQVKATVILQRAFR 1454
A IQR +R Y + Y+ + + ++IQS FR + +Q+K Q +A V++Q+ +R
Sbjct: 1550 AAAVIQRCYRKY----KQYALYKKMTQAAILIQSKFRSYYEQKKFQQSRRAAVLIQKYYR 1605
Query: 1455 EW-HLRKQAKEENSAIIIQSWYR 1476
+ K+ + +A+I+Q R
Sbjct: 1606 SYKKCGKRRQARRTAVIVQQKLR 1628
Score = 38.1 bits (87), Expect = 0.15
Identities = 31/106 (29%), Positives = 54/106 (50%), Gaps = 20/106 (18%)
Query: 1269 AARLIQTTWRKYKLKTDLKRHQEREKAARIIQLAVINFLAKQRLRKRVNAALVIQKYWR- 1327
AA +IQ +RKYK +++ +AA +IQ ++ +++ ++ AA++IQKY+R
Sbjct: 1550 AAAVIQRCYRKYK---QYALYKKMTQAAILIQSKFRSYYEQKKFQQSRRAAVLIQKYYRS 1606
Query: 1328 -------------RVLAQRKLLMLKKEKLEKVQNKAASLIQGYWRR 1360
V+ Q+K L+ L K Q++AA I + RR
Sbjct: 1607 YKKCGKRRQARRTAVIVQQK---LRSSLLTKKQDQAARKIMRFLRR 1649
Score = 37.7 bits (86), Expect = 0.20
Identities = 22/85 (25%), Positives = 47/85 (55%), Gaps = 1/85 (1%)
Query: 2930 QEIKNSTIKIQAMWRRYRAKKYLCKVK-AACKIQAWYRCWRAHKEYLAILKAVKIIQGCF 2988
+E+ + +Q +R+Y+ + + + AA IQ YR ++ + Y + +A +IQ F
Sbjct: 1522 RELYEAARLVQTAFRKYKGRPLREQQEVAAAVIQRCYRKYKQYALYKKMTQAAILIQSKF 1581
Query: 2989 YTKLERTRFLNVRASAIIIQRKWRA 3013
+ E+ +F R +A++IQ+ +R+
Sbjct: 1582 RSYYEQKKFQQSRRAAVLIQKYYRS 1606
Score = 35.4 bits (80), Expect = 0.99
Identities = 32/139 (23%), Positives = 65/139 (46%), Gaps = 5/139 (3%)
Query: 2897 LSAKHQRQVYLQIRSSVIIIQARSKGFIQKRKFQEIKNSTIKIQAMWRRYRAKKYLCKV- 2955
LS QR++Y R ++Q + + + ++ + + IQ +R+Y+ K+
Sbjct: 1516 LSDHEQRELYEAAR----LVQTAFRKYKGRPLREQQEVAAAVIQRCYRKYKQYALYKKMT 1571
Query: 2956 KAACKIQAWYRCWRAHKEYLAILKAVKIIQGCFYTKLERTRFLNVRASAIIIQRKWRAIL 3015
+AA IQ+ +R + K++ +A +IQ + + + + R +A+I+Q+K R+ L
Sbjct: 1572 QAAILIQSKFRSYYEQKKFQQSRRAAVLIQKYYRSYKKCGKRRQARRTAVIVQQKLRSSL 1631
Query: 3016 PAKIAHEHFLMIKRHRAAC 3034
K + I R C
Sbjct: 1632 LTKKQDQAARKIMRFLRRC 1650
Score = 33.1 bits (74), Expect = 4.9
Identities = 31/120 (25%), Positives = 57/120 (47%), Gaps = 6/120 (5%)
Query: 3171 EHEGQECLSQRNRAASVIQKAVRHFLLRKKQEKFTSGIIKIQALWRGYSWRKKNDCTKIK 3230
+++G+ Q+ AA+VIQ+ R + +K T I IQ+ +R Y +KK ++
Sbjct: 1537 KYKGRPLREQQEVAAAVIQRCYRKYKQYALYKKMTQAAILIQSKFRSYYEQKKFQQSRRA 1596
Query: 3231 AIRLSLQVVNREIREENKLYKRTALALHY-----LLTYKHLSAILEALKHLEVVTRLSPL 3285
A+ + + + + + +RTA+ + LLT K A + ++ L R SPL
Sbjct: 1597 AVLIQKYYRSYKKCGKRRQARRTAVIVQQKLRSSLLTKKQDQAARKIMRFLR-RCRHSPL 1655
>gi|112382252 spectrin, beta, non-erythrocytic 1 isoform 2 [Homo
sapiens]
Length = 2155
Score = 59.7 bits (143), Expect = 5e-08
Identities = 56/201 (27%), Positives = 86/201 (42%), Gaps = 54/201 (26%)
Query: 965 VTNLAVDLQCGVRLVRTMELLTQNWDLSKKLRIPAISRLQK--MHNVDIVLQVLKSRGIE 1022
+T+L DL+ G L++ +E+L+ ++L P R++ + NVD LQ LK + +
Sbjct: 62 ITDLYTDLRDGRMLIKLLEVLS-----GERLPKPTKGRMRIHCLENVDKALQFLKEQRVH 116
Query: 1023 LSDEHGNTILSKDIVDRHREKTLRLLWKIAFAFQV-DISLNLDQLKEEIAFLKHTKSIKK 1081
L + + S DIVD + TL L+W I FQ+ DIS+ + KE
Sbjct: 117 LEN-----MGSHDIVDGNHRLTLGLIWTIILRFQIQDISVETEDNKE------------- 158
Query: 1082 TISLLSCHSDDLINKKKGKRDSGSFEQYSENIKLLMDWVNAVCAFY-NKKVENFTVSFSD 1140
KK +D+ L+ W A Y N + NFT S+ D
Sbjct: 159 ---------------KKSAKDA------------LLLWCQMKTAGYPNVNIHNFTTSWRD 191
Query: 1141 GRVLCYLIHHYHPCYVPFDAI 1161
G LIH + P + FD +
Sbjct: 192 GMAFNALIHKHRPDLIDFDKL 212
>gi|112382250 spectrin, beta, non-erythrocytic 1 isoform 1 [Homo
sapiens]
Length = 2364
Score = 59.7 bits (143), Expect = 5e-08
Identities = 56/201 (27%), Positives = 86/201 (42%), Gaps = 54/201 (26%)
Query: 965 VTNLAVDLQCGVRLVRTMELLTQNWDLSKKLRIPAISRLQK--MHNVDIVLQVLKSRGIE 1022
+T+L DL+ G L++ +E+L+ ++L P R++ + NVD LQ LK + +
Sbjct: 75 ITDLYTDLRDGRMLIKLLEVLS-----GERLPKPTKGRMRIHCLENVDKALQFLKEQRVH 129
Query: 1023 LSDEHGNTILSKDIVDRHREKTLRLLWKIAFAFQV-DISLNLDQLKEEIAFLKHTKSIKK 1081
L + + S DIVD + TL L+W I FQ+ DIS+ + KE
Sbjct: 130 LEN-----MGSHDIVDGNHRLTLGLIWTIILRFQIQDISVETEDNKE------------- 171
Query: 1082 TISLLSCHSDDLINKKKGKRDSGSFEQYSENIKLLMDWVNAVCAFY-NKKVENFTVSFSD 1140
KK +D+ L+ W A Y N + NFT S+ D
Sbjct: 172 ---------------KKSAKDA------------LLLWCQMKTAGYPNVNIHNFTTSWRD 204
Query: 1141 GRVLCYLIHHYHPCYVPFDAI 1161
G LIH + P + FD +
Sbjct: 205 GMAFNALIHKHRPDLIDFDKL 225
>gi|194272142 myosin IXB isoform 2 [Homo sapiens]
Length = 2022
Score = 59.3 bits (142), Expect = 6e-08
Identities = 33/109 (30%), Positives = 68/109 (62%), Gaps = 5/109 (4%)
Query: 1753 KAVISLQSYFRMRKARQYYLKMYKAIIVIQNYYHAYKAQVNQRKNFLQVKKAATCLQAAY 1812
K + L+ R + ++ + I+++Q+++ V +R++FLQ+K+AA +QA +
Sbjct: 935 KTKVFLKETERQALQETLHREVVRKILLLQSWFR----MVLERRHFLQMKRAAVTIQACW 990
Query: 1813 RGYKVRQLIKQQSIAALKIQSAFRGYNKRVKYQSVLQSIIKIQRWYRAY 1861
R Y+VR+ + +++ AA+ +Q+++RGY +R Y+ QSII++Q R +
Sbjct: 991 RSYRVRRAL-ERTQAAVYLQASWRGYWQRKLYRHQKQSIIRLQSLCRGH 1038
Score = 58.5 bits (140), Expect = 1e-07
Identities = 30/96 (31%), Positives = 59/96 (61%), Gaps = 5/96 (5%)
Query: 1753 KAVISLQSYFRMRKARQYYLKMYKAIIVIQNYYHAYKAQVNQRKNFLQVKKAATCLQAAY 1812
+ ++ LQS+FRM R+++L+M +A + IQ + +Y+ + L+ +AA LQA++
Sbjct: 958 RKILLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRV-----RRALERTQAAVYLQASW 1012
Query: 1813 RGYKVRQLIKQQSIAALKIQSAFRGYNKRVKYQSVL 1848
RGY R+L + Q + +++QS RG+ +R + ++
Sbjct: 1013 RGYWQRKLYRHQKQSIIRLQSLCRGHLQRKSFSQMI 1048
Score = 58.2 bits (139), Expect = 1e-07
Identities = 36/112 (32%), Positives = 66/112 (58%), Gaps = 12/112 (10%)
Query: 2821 IQKAFCRMVTRKLETQKCAALRIQFFLQMAVYRRRFVQQKRAAITLQHYFRTWQTRKQFL 2880
+Q+ R V RK+ L +Q + +M + RR F+Q KRAA+T+Q +R+++ R+ L
Sbjct: 948 LQETLHREVVRKI-------LLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVRRA-L 999
Query: 2881 LYRKAAVVLQNHYRAFLSAKHQRQVYLQIRSSVIIIQARSKGFIQKRKFQEI 2932
+AAV LQ +R + QR++Y + S+I +Q+ +G +Q++ F ++
Sbjct: 1000 ERTQAAVYLQASWRGY----WQRKLYRHQKQSIIRLQSLCRGHLQRKSFSQM 1047
Score = 56.6 bits (135), Expect = 4e-07
Identities = 46/151 (30%), Positives = 78/151 (51%), Gaps = 30/151 (19%)
Query: 1526 KGKIERTNYLQKRAAAIQLQAAFRRLKAHNLCRQI-RAACVIQSYWRMRQDRVRFLNLKK 1584
K KI++ NY Q + L+ R+ L R++ R ++QS++RM +R FL
Sbjct: 923 KMKIDKRNY-QIGKTKVFLKETERQALQETLHREVVRKILLLQSWFRMVLERRHFL---- 977
Query: 1585 TIIKFQAHVRKHQQRQKYKKMKKAAVIIQTHFRAYIFAMKVLASYQKTRSAVIVLQSAYR 1644
+MK+AAV IQ +R+Y +V + ++T++AV LQ+++R
Sbjct: 978 -------------------QMKRAAVTIQACWRSY----RVRRALERTQAAV-YLQASWR 1013
Query: 1645 GMQARKMYIHILTSVIKIQSYYRAYVSKKEF 1675
G RK+Y H S+I++QS R ++ +K F
Sbjct: 1014 GYWQRKLYRHQKQSIIRLQSLCRGHLQRKSF 1044
Score = 55.5 bits (132), Expect = 9e-07
Identities = 35/130 (26%), Positives = 67/130 (51%), Gaps = 5/130 (3%)
Query: 1476 RMHKELRKYIYIRSCVVIIQKRFRCFQAQKLYKRRKESILTIQKYYKAYLKGKIERTNYL 1535
+M + R Y I V +++ R + L++ IL +Q +++ L ER ++L
Sbjct: 923 KMKIDKRNY-QIGKTKVFLKETERQALQETLHREVVRKILLLQSWFRMVL----ERRHFL 977
Query: 1536 QKRAAAIQLQAAFRRLKAHNLCRQIRAACVIQSYWRMRQDRVRFLNLKKTIIKFQAHVRK 1595
Q + AA+ +QA +R + + +AA +Q+ WR R + + K++II+ Q+ R
Sbjct: 978 QMKRAAVTIQACWRSYRVRRALERTQAAVYLQASWRGYWQRKLYRHQKQSIIRLQSLCRG 1037
Query: 1596 HQQRQKYKKM 1605
H QR+ + +M
Sbjct: 1038 HLQRKSFSQM 1047
Score = 52.0 bits (123), Expect = 1e-05
Identities = 56/277 (20%), Positives = 119/277 (42%), Gaps = 28/277 (10%)
Query: 1659 VIKIQSYYRAYVSKKEFLSLKNATIKLQSTVKMKQTRKQYLHLRAAALFIQQCYRSKKIA 1718
++K + + + K L K+ + + T+ +T K LHL + I+
Sbjct: 777 ILKSKGIKQKQIIPKNLLDSKSLKLIISMTLH-DRTTKSLLHLHKKK-------KPPSIS 828
Query: 1719 AQKREEYMQMRESCIKLQAF----VRGYLVRKQMRLQRKAVISLQSYFRMRKARQYYLKM 1774
AQ + ++ E+ K + F +R +K++ + V+ Y M + +
Sbjct: 829 AQFQTSLNKLLEALGKAEPFFIRCIRSNAEKKELCFDDELVLQQLRYTGMLETVRIRRSG 888
Query: 1775 YKAIIVIQNYYHAYKAQVNQRKNFLQVKKAATC---LQAAYRGYKVRQLIKQQSIAALKI 1831
Y A Q++ ++ L K A C + K+ + Q + +
Sbjct: 889 YSAKYTFQDFTEQFQV--------LLPKDAQPCREVISTLLEKMKIDKRNYQIGKTKVFL 940
Query: 1832 QSAFRGYNKRVKYQSVLQSIIKIQRWYRAYKTLHDTRTHFLKTKAAVISLQSAYRGWKVR 1891
+ R + ++ V++ I+ +Q W+R R HFL+ K A +++Q+ +R ++VR
Sbjct: 941 KETERQALQETLHREVVRKILLLQSWFRMVLE----RRHFLQMKRAAVTIQACWRSYRVR 996
Query: 1892 KQIRREHQAALKIQSAFRMAKAQKQFRLFKTAALVIQ 1928
+ + R QAA+ +Q+++R +K +R K + + +Q
Sbjct: 997 RALERT-QAAVYLQASWRGYWQRKLYRHQKQSIIRLQ 1032
Score = 52.0 bits (123), Expect = 1e-05
Identities = 41/164 (25%), Positives = 86/164 (52%), Gaps = 18/164 (10%)
Query: 2439 RKYRATICAKHKL----YQFLHLRKAAITIQSSYRRLMVKKKLQEMQRAAVLIQATFRMY 2494
R+ +T+ K K+ YQ + K + ++ + R+ + + +E+ R +L+Q+ FRM
Sbjct: 914 REVISTLLEKMKIDKRNYQ---IGKTKVFLKETERQALQETLHREVVRKILLLQSWFRMV 970
Query: 2495 RTYITFQTWKHASILIQQHYRTYRAAKLQRENYIRQWHSAVVIQAAYKGMKARQLLREKH 2554
F K A++ IQ +R+YR + + + +AV +QA+++G R+L R +
Sbjct: 971 LERRHFLQMKRAAVTIQACWRSYRVRRA-----LERTQAAVYLQASWRGYWQRKLYRHQK 1025
Query: 2555 KASIVIQSTYRMYRQYCFYQKLQWATKIIQEKYRANKKKQKVFQ 2598
++ I +QS R + Q + +++I EK +A +K+++ +
Sbjct: 1026 QSIIRLQSLCRGHLQRKSF------SQMISEKQKAEEKEREALE 1063
Score = 51.2 bits (121), Expect = 2e-05
Identities = 30/90 (33%), Positives = 51/90 (56%), Gaps = 5/90 (5%)
Query: 1685 LQSTVKMKQTRKQYLHLRAAALFIQQCYRSKKIAAQKREEYMQMRESCIKLQAFVRGYLV 1744
LQS +M R+ +L ++ AA+ IQ C+RS ++ ++ ++ + LQA RGY
Sbjct: 963 LQSWFRMVLERRHFLQMKRAAVTIQACWRSYRV-----RRALERTQAAVYLQASWRGYWQ 1017
Query: 1745 RKQMRLQRKAVISLQSYFRMRKARQYYLKM 1774
RK R Q++++I LQS R R+ + +M
Sbjct: 1018 RKLYRHQKQSIIRLQSLCRGHLQRKSFSQM 1047
Score = 50.8 bits (120), Expect = 2e-05
Identities = 30/104 (28%), Positives = 62/104 (59%), Gaps = 8/104 (7%)
Query: 1961 KTLRRQLQRQHKCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYRAYSIGREQNHLYLKT 2020
+TL R++ R+ +++QS++RM ++++ + MK+AA+ IQ +R+Y + R L+
Sbjct: 950 ETLHREVVRK---ILLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVRRA-----LER 1001
Query: 2021 KAAVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYA 2064
A V LQ+++RG RK + ++ + +QS R + +K ++
Sbjct: 1002 TQAAVYLQASWRGYWQRKLYRHQKQSIIRLQSLCRGHLQRKSFS 1045
Score = 48.5 bits (114), Expect = 1e-04
Identities = 36/135 (26%), Positives = 69/135 (51%), Gaps = 10/135 (7%)
Query: 1982 RMHVQQKKWKIMKKAALLIQKYYRAYSIGREQNHLYLKTKAAVVTLQSAYRGMKVRKRIK 2041
+M + ++ ++I K L + +A Q L+ + ++ LQS +R + R+
Sbjct: 923 KMKIDKRNYQIGKTKVFLKETERQAL-----QETLHREVVRKILLLQSWFRMVLERRHFL 977
Query: 2042 DCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKITNHQHKEYLNLKKTAIKIQ 2101
+AAVTIQ+ +R+Y+ ++ +A A+ +Q +RG Q K Y + K++ I++Q
Sbjct: 978 QMKRAAVTIQACWRSYRVRRALERTQA-AVYLQASWRGY----WQRKLYRHQKQSIIRLQ 1032
Query: 2102 SVYRGIRVRRHIQHM 2116
S+ RG R+ M
Sbjct: 1033 SLCRGHLQRKSFSQM 1047
Score = 48.5 bits (114), Expect = 1e-04
Identities = 28/116 (24%), Positives = 60/116 (51%)
Query: 2902 QRQVYLQIRSSVIIIQARSKGFIQKRKFQEIKNSTIKIQAMWRRYRAKKYLCKVKAACKI 2961
Q ++ ++ ++++Q+ + +++R F ++K + + IQA WR YR ++ L + +AA +
Sbjct: 949 QETLHREVVRKILLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVRRALERTQAAVYL 1008
Query: 2962 QAWYRCWRAHKEYLAILKAVKIIQGCFYTKLERTRFLNVRASAIIIQRKWRAILPA 3017
QA +R + K Y +++ +Q L+R F + + + K R L A
Sbjct: 1009 QASWRGYWQRKLYRHQKQSIIRLQSLCRGHLQRKSFSQMISEKQKAEEKEREALEA 1064
Score = 47.8 bits (112), Expect = 2e-04
Identities = 30/92 (32%), Positives = 48/92 (52%), Gaps = 5/92 (5%)
Query: 1902 LKIQSAFRMAKAQKQFRLFKTAALVIQQNFRAWTAGRKQCMEYIELRHAVLVLQSMWKGK 1961
L +QS FRM ++ F K AA+ IQ +R++ R +E A + LQ+ W+G
Sbjct: 961 LLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVRRA-----LERTQAAVYLQASWRGY 1015
Query: 1962 TLRRQLQRQHKCAIIIQSYYRMHVQQKKWKIM 1993
R+ + Q + I +QS R H+Q+K + M
Sbjct: 1016 WQRKLYRHQKQSIIRLQSLCRGHLQRKSFSQM 1047
Score = 47.4 bits (111), Expect = 3e-04
Identities = 27/94 (28%), Positives = 51/94 (54%), Gaps = 10/94 (10%)
Query: 2971 HKEYLAILKAVKIIQGCFYTKLERTRFLNVRASAIIIQRKWRAILPAKIAHEHFLMIKRH 3030
H+E +++ + ++Q F LER FL ++ +A+ IQ WR+ + ++R
Sbjct: 953 HRE---VVRKILLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVRRA-------LERT 1002
Query: 3031 RAACLIQAHYRGYKGRQVFLRQKSAALIIQKYIR 3064
+AA +QA +RGY R+++ QK + + +Q R
Sbjct: 1003 QAAVYLQASWRGYWQRKLYRHQKQSIIRLQSLCR 1036
Score = 47.0 bits (110), Expect = 3e-04
Identities = 41/163 (25%), Positives = 76/163 (46%), Gaps = 12/163 (7%)
Query: 2264 IAATLIQRRFRTLMMRRRFLSLKKTAILIQRKYRAHLCTKHHLQFLQVQNAVIKIQSSYR 2323
+ +TL+++ + + +R + KT + ++ R L H + V ++ +QS +R
Sbjct: 916 VISTLLEK----MKIDKRNYQIGKTKVFLKETERQALQETLHRE---VVRKILLLQSWFR 968
Query: 2324 RWMIRKRMREMHRAATFIQSTFRMHRLHMRYQALKQASVVIQQQYQANRAAKLQRQHYLR 2383
+ R+ +M RAA IQ+ +R +R+ R QA+V +Q ++ QR+ Y
Sbjct: 969 MVLERRHFLQMKRAAVTIQACWRSYRVR-RALERTQAAVYLQASWR----GYWQRKLYRH 1023
Query: 2384 QRHSAVILQAAFRGMKTRRHLKSMHSSATLIQSRFRSLLVRRR 2426
Q+ S + LQ+ RG R+ M S + + R L R
Sbjct: 1024 QKQSIIRLQSLCRGHLQRKSFSQMISEKQKAEEKEREALEAAR 1066
Score = 46.6 bits (109), Expect = 4e-04
Identities = 29/126 (23%), Positives = 62/126 (49%), Gaps = 7/126 (5%)
Query: 1426 IIQSMFRKWKQRKMQSQVKATVILQRAFREWHLRKQAKEE--NSAIIIQSWYRMHKELRK 1483
+I ++ K K K Q+ T + + L++ E +++QSW+RM E R
Sbjct: 916 VISTLLEKMKIDKRNYQIGKTKVFLKETERQALQETLHREVVRKILLLQSWFRMVLERRH 975
Query: 1484 YIYIRSCVVIIQKRFRCFQAQKLYKRRKESILTIQKYYKAYLKGKIERTNYLQKRAAAIQ 1543
++ ++ V IQ +R ++ ++ +R + ++ Y +A +G +R Y ++ + I+
Sbjct: 976 FLQMKRAAVTIQACWRSYRVRRALERTQAAV-----YLQASWRGYWQRKLYRHQKQSIIR 1030
Query: 1544 LQAAFR 1549
LQ+ R
Sbjct: 1031 LQSLCR 1036
Score = 45.1 bits (105), Expect = 0.001
Identities = 36/152 (23%), Positives = 73/152 (48%), Gaps = 12/152 (7%)
Query: 2038 KRIKDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKITNHQHKEYLNLKKTA 2097
K + C + T+ K + K+ Y + + + + ++ T H+ + +
Sbjct: 908 KDAQPCREVISTLLEKMKI--DKRNYQIGKTKVFLKETERQALQETLHRE-----VVRKI 960
Query: 2098 IKIQSVYRGIRVRRHIQHMHRAATFIKAMFKMHQSRISYHTMRKAAIVIQVRCRAYYQGK 2157
+ +QS +R + RRH M RAA I+A ++ ++ R + +AA+ +Q R Y+Q K
Sbjct: 961 LLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVRRALE-RTQAAVYLQASWRGYWQRK 1019
Query: 2158 MQREKYLTILKAVKVLQASFRGVRVRRTLRKM 2189
+ R + +I++ LQ+ RG R++ +M
Sbjct: 1020 LYRHQKQSIIR----LQSLCRGHLQRKSFSQM 1047
Score = 43.1 bits (100), Expect = 0.005
Identities = 31/146 (21%), Positives = 76/146 (52%), Gaps = 2/146 (1%)
Query: 1409 RRKQDQQRYEMLKSSTLIIQSMFRKWKQRKMQSQVKATVILQRAFREWHLRKQAKE-ENS 1467
+ K D++ Y++ K+ + ++ + ++ + V+ ++LQ FR R+ + + +
Sbjct: 923 KMKIDKRNYQIGKTKVFLKETERQALQETLHREVVRKILLLQSWFRMVLERRHFLQMKRA 982
Query: 1468 AIIIQSWYRMHKELRKYIYIRSCVVIIQKRFRCFQAQKLYKRRKESILTIQKYYKAYLKG 1527
A+ IQ+ +R ++ +R+ + V +Q +R + +KLY+ +K+SI+ +Q + +L+
Sbjct: 983 AVTIQACWRSYR-VRRALERTQAAVYLQASWRGYWQRKLYRHQKQSIIRLQSLCRGHLQR 1041
Query: 1528 KIERTNYLQKRAAAIQLQAAFRRLKA 1553
K +K+ A + + A +A
Sbjct: 1042 KSFSQMISEKQKAEEKEREALEAARA 1067
Score = 41.6 bits (96), Expect = 0.014
Identities = 35/168 (20%), Positives = 80/168 (47%), Gaps = 22/168 (13%)
Query: 2318 IQSSYRRWMIRKRMREMHRAATFIQSTFRMHRLHMRYQALKQASVVIQQQYQANRAAKLQ 2377
I + + I KR ++ + F++ T R ++ + + +++Q ++ L+
Sbjct: 917 ISTLLEKMKIDKRNYQIGKTKVFLKETERQALQETLHREVVRKILLLQSWFRM----VLE 972
Query: 2378 RQHYLRQRHSAVILQAAFRGMKTRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFV 2437
R+H+L+ + +AV +QA +R + RR L+ +A +Q+ +R R+ + K++ I +
Sbjct: 973 RRHFLQMKRAAVTIQACWRSYRVRRALERT-QAAVYLQASWRGYWQRKLYRHQKQSIIRL 1031
Query: 2438 QRKYRATICAKHKLYQFLHLRKAAITIQSSYRRLMVKKKLQEMQRAAV 2485
Q ++C H + +S + + K+K +E +R A+
Sbjct: 1032 Q-----SLCRGH------------LQRKSFSQMISEKQKAEEKEREAL 1062
Score = 41.6 bits (96), Expect = 0.014
Identities = 29/94 (30%), Positives = 41/94 (43%), Gaps = 19/94 (20%)
Query: 3141 VNSVICIQRWFRARLQEKRFIQKYHSIKKIEHEGQECLSQRNRAASVIQKAVRHFLLRKK 3200
V ++ +Q WFR L+ + F+ Q RAA IQ R + +R+
Sbjct: 957 VRKILLLQSWFRMVLERRHFL------------------QMKRAAVTIQACWRSYRVRRA 998
Query: 3201 QEKFTSGIIKIQALWRGYSWRKKNDCTKIKAIRL 3234
E+ T + +QA WRGY RK K IRL
Sbjct: 999 LER-TQAAVYLQASWRGYWQRKLYRHQKQSIIRL 1031
Score = 41.2 bits (95), Expect = 0.018
Identities = 31/104 (29%), Positives = 52/104 (50%), Gaps = 5/104 (4%)
Query: 1340 KEKLEKVQNKAASLIQGYWRRYSTRQRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVT 1399
+E L + + L+Q ++R R+ FL++K ++ +Q+ R + +R A V
Sbjct: 949 QETLHREVVRKILLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVRRALER-TQAAVY 1007
Query: 1400 IQRHWRAYLRRKQDQQRYEMLKSSTLIIQSMFRKWKQRKMQSQV 1443
+Q WR Y +RK Y K S + +QS+ R QRK SQ+
Sbjct: 1008 LQASWRGYWQRK----LYRHQKQSIIRLQSLCRGHLQRKSFSQM 1047
Score = 40.0 bits (92), Expect = 0.040
Identities = 40/165 (24%), Positives = 73/165 (44%), Gaps = 13/165 (7%)
Query: 2612 FQDMNIKKQI---QEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQRRYRK-----LTA 2663
FQD + Q+ ++ +I + KI K + T V ++ R+ L
Sbjct: 895 FQDFTEQFQVLLPKDAQPCREVISTLLEKMKIDKRNYQIGKTKVFLKETERQALQETLHR 954
Query: 2664 VRTQAVICIQSYYRGFKVRKDIQNMHRAATLIQSFYRMHRAKVDYETKKTAIVVIQNYYR 2723
+ ++ +QS++R R+ M RAA IQ+ +R +R + E + A V +Q +R
Sbjct: 955 EVVRKILLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVRRALE-RTQAAVYLQASWR 1013
Query: 2724 LYVRVKTERKNFLAVQKSVRTIQAAFRGMKVRQKLKNVSEEKMAA 2768
Y +RK + ++S+ +Q+ RG R+ + EK A
Sbjct: 1014 GY----WQRKLYRHQKQSIIRLQSLCRGHLQRKSFSQMISEKQKA 1054
Score = 39.7 bits (91), Expect = 0.053
Identities = 22/91 (24%), Positives = 48/91 (52%), Gaps = 1/91 (1%)
Query: 2124 KAMFKMHQSRISYHTMRKAAIVIQVRCRAYYQGKMQREKYLTILKAVKVLQASFRGVRVR 2183
K K + + T+ + + + +++++ ++R +L + +A +QA +R RVR
Sbjct: 937 KVFLKETERQALQETLHREVVRKILLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVR 996
Query: 2184 RTLRKMQTAATLIQSNYRRYRQQTYFNKLKK 2214
R L + Q AA +Q+++R Y Q+ + K+
Sbjct: 997 RALERTQ-AAVYLQASWRGYWQRKLYRHQKQ 1026
Score = 39.7 bits (91), Expect = 0.053
Identities = 33/114 (28%), Positives = 49/114 (42%), Gaps = 16/114 (14%)
Query: 3072 ERIKYIEFKKSTVILQALVRGWLVRKRFLEQRAKIRLLHFTAAAYYHLNAVRIQRAYKLY 3131
ER +++ K++ V +QA R + VR R L T AA Y +Q +++ Y
Sbjct: 972 ERRHFLQMKRAAVTIQACWRSYRVR----------RALERTQAAVY------LQASWRGY 1015
Query: 3132 LAVKNANKQVNSVICIQRWFRARLQEKRFIQKYHSIKKIEHEGQECLSQRNRAA 3185
K Q S+I +Q R LQ K F Q +K E + +E L A
Sbjct: 1016 WQRKLYRHQKQSIIRLQSLCRGHLQRKSFSQMISEKQKAEEKEREALEAARAGA 1069
Score = 39.3 bits (90), Expect = 0.069
Identities = 23/88 (26%), Positives = 48/88 (54%), Gaps = 5/88 (5%)
Query: 1375 IILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQRYEMLKSSTLIIQSMFRKW 1434
++LQS RM++ + + A VTIQ WR+Y R+ ++ + + +Q+ +R +
Sbjct: 961 LLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVRRALER-----TQAAVYLQASWRGY 1015
Query: 1435 KQRKMQSQVKATVILQRAFREWHLRKQA 1462
QRK+ K ++I ++ HL++++
Sbjct: 1016 WQRKLYRHQKQSIIRLQSLCRGHLQRKS 1043
Score = 37.7 bits (86), Expect = 0.20
Identities = 30/125 (24%), Positives = 58/125 (46%), Gaps = 5/125 (4%)
Query: 2088 KEYLNLKKTAIKIQSVYRGIRVRRHIQHMHRAATFIKAMFKMHQSRISYHTMRKAAIVIQ 2147
K + KT + ++ R + + R +++ F+M R + M++AA+ IQ
Sbjct: 928 KRNYQIGKTKVFLKETERQALQETLHREVVRKILLLQSWFRMVLERRHFLQMKRAAVTIQ 987
Query: 2148 VRCRAYYQGKMQREKYLTILKAVKVLQASFRGVRVRRTLRKMQTAATLIQSNYRRYRQQT 2207
R+Y + + L +A LQAS+RG R+ R + + +QS R + Q+
Sbjct: 988 ACWRSY-----RVRRALERTQAAVYLQASWRGYWQRKLYRHQKQSIIRLQSLCRGHLQRK 1042
Query: 2208 YFNKL 2212
F+++
Sbjct: 1043 SFSQM 1047
Score = 37.0 bits (84), Expect = 0.34
Identities = 27/104 (25%), Positives = 51/104 (49%), Gaps = 4/104 (3%)
Query: 2231 IQFQRYNKLRHSVIYIQAIFRGKKARRHLKMMHIAATLIQRRFRTLMMRRRFLSLKKTAI 2290
+Q + ++ ++ +Q+ FR RRH M AA IQ +R+ +RR L + A+
Sbjct: 948 LQETLHREVVRKILLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVRRA-LERTQAAV 1006
Query: 2291 LIQRKYRAHLCTKHHLQFLQVQNAVIKIQSSYRRWMIRKRMREM 2334
+Q +R + K + + ++I++QS R + RK +M
Sbjct: 1007 YLQASWRGYWQRK---LYRHQKQSIIRLQSLCRGHLQRKSFSQM 1047
Score = 36.2 bits (82), Expect = 0.58
Identities = 31/157 (19%), Positives = 72/157 (45%), Gaps = 16/157 (10%)
Query: 1571 RMRQDRVRFLNLKKTIIKFQAHVRKHQQRQKYKKMKKAAVIIQTHFRAYIFAMKVLASYQ 1630
+M+ D+ R + KT + + R+ Q ++++ + +++Q+ FR + L
Sbjct: 923 KMKIDK-RNYQIGKTKVFLKETERQALQETLHREVVRKILLLQSWFRMVLERRHFL---- 977
Query: 1631 KTRSAVIVLQSAYRGMQARKMYIHILTSVIKIQSYYRAYVSKKEFLSLKNATIKLQSTVK 1690
+ + A + +Q+ +R + R+ + + + +Q+ +R Y +K + K + I+LQS +
Sbjct: 978 QMKRAAVTIQACWRSYRVRRA-LERTQAAVYLQASWRGYWQRKLYRHQKQSIIRLQSLCR 1036
Query: 1691 MKQTRKQYLHLRAAALFIQQCYRSKKIAAQKREEYMQ 1727
RK + Q K+ A +K E ++
Sbjct: 1037 GHLQRKSF----------SQMISEKQKAEEKEREALE 1063
Score = 35.4 bits (80), Expect = 0.99
Identities = 22/81 (27%), Positives = 46/81 (56%), Gaps = 8/81 (9%)
Query: 2715 IVVIQNYYRLYVRVKTERKNFLAVQKSVRTIQAAFRGMKVRQKLKNVSEEKMAAIVNQSA 2774
I+++Q+++R+ + ER++FL ++++ TIQA +R +VR+ L E AA+ Q++
Sbjct: 960 ILLLQSWFRMVL----ERRHFLQMKRAAVTIQACWRSYRVRRAL----ERTQAAVYLQAS 1011
Query: 2775 LCCYRSKTQYEAVQSEGVMIQ 2795
Y + Y + + +Q
Sbjct: 1012 WRGYWQRKLYRHQKQSIIRLQ 1032
Score = 32.3 bits (72), Expect = 8.4
Identities = 29/103 (28%), Positives = 50/103 (48%), Gaps = 8/103 (7%)
Query: 1263 LRKEIRAARLIQTTWRKYKLKTDLKRHQEREKAARIIQLAVINFLAKQRLRKRVNAALVI 1322
L +E+ L+ +W + L+ +RH + K A + A +R +R AA+ +
Sbjct: 952 LHREVVRKILLLQSWFRMVLE---RRHFLQMKRAAVTIQACWRSYRVRRALERTQAAVYL 1008
Query: 1323 QKYWRRVLAQRKLLMLKKEKLEKVQNKAASLIQGYWRRYSTRQ 1365
Q WR QRKL +K+ + ++Q SL +G+ +R S Q
Sbjct: 1009 QASWRGYW-QRKLYRHQKQSIIRLQ----SLCRGHLQRKSFSQ 1046
>gi|33356170 myosin IXB isoform 1 [Homo sapiens]
Length = 2157
Score = 59.3 bits (142), Expect = 6e-08
Identities = 33/109 (30%), Positives = 68/109 (62%), Gaps = 5/109 (4%)
Query: 1753 KAVISLQSYFRMRKARQYYLKMYKAIIVIQNYYHAYKAQVNQRKNFLQVKKAATCLQAAY 1812
K + L+ R + ++ + I+++Q+++ V +R++FLQ+K+AA +QA +
Sbjct: 935 KTKVFLKETERQALQETLHREVVRKILLLQSWFR----MVLERRHFLQMKRAAVTIQACW 990
Query: 1813 RGYKVRQLIKQQSIAALKIQSAFRGYNKRVKYQSVLQSIIKIQRWYRAY 1861
R Y+VR+ + +++ AA+ +Q+++RGY +R Y+ QSII++Q R +
Sbjct: 991 RSYRVRRAL-ERTQAAVYLQASWRGYWQRKLYRHQKQSIIRLQSLCRGH 1038
Score = 58.5 bits (140), Expect = 1e-07
Identities = 30/96 (31%), Positives = 59/96 (61%), Gaps = 5/96 (5%)
Query: 1753 KAVISLQSYFRMRKARQYYLKMYKAIIVIQNYYHAYKAQVNQRKNFLQVKKAATCLQAAY 1812
+ ++ LQS+FRM R+++L+M +A + IQ + +Y+ + L+ +AA LQA++
Sbjct: 958 RKILLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRV-----RRALERTQAAVYLQASW 1012
Query: 1813 RGYKVRQLIKQQSIAALKIQSAFRGYNKRVKYQSVL 1848
RGY R+L + Q + +++QS RG+ +R + ++
Sbjct: 1013 RGYWQRKLYRHQKQSIIRLQSLCRGHLQRKSFSQMI 1048
Score = 58.2 bits (139), Expect = 1e-07
Identities = 36/112 (32%), Positives = 66/112 (58%), Gaps = 12/112 (10%)
Query: 2821 IQKAFCRMVTRKLETQKCAALRIQFFLQMAVYRRRFVQQKRAAITLQHYFRTWQTRKQFL 2880
+Q+ R V RK+ L +Q + +M + RR F+Q KRAA+T+Q +R+++ R+ L
Sbjct: 948 LQETLHREVVRKI-------LLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVRRA-L 999
Query: 2881 LYRKAAVVLQNHYRAFLSAKHQRQVYLQIRSSVIIIQARSKGFIQKRKFQEI 2932
+AAV LQ +R + QR++Y + S+I +Q+ +G +Q++ F ++
Sbjct: 1000 ERTQAAVYLQASWRGY----WQRKLYRHQKQSIIRLQSLCRGHLQRKSFSQM 1047
Score = 56.6 bits (135), Expect = 4e-07
Identities = 46/151 (30%), Positives = 78/151 (51%), Gaps = 30/151 (19%)
Query: 1526 KGKIERTNYLQKRAAAIQLQAAFRRLKAHNLCRQI-RAACVIQSYWRMRQDRVRFLNLKK 1584
K KI++ NY Q + L+ R+ L R++ R ++QS++RM +R FL
Sbjct: 923 KMKIDKRNY-QIGKTKVFLKETERQALQETLHREVVRKILLLQSWFRMVLERRHFL---- 977
Query: 1585 TIIKFQAHVRKHQQRQKYKKMKKAAVIIQTHFRAYIFAMKVLASYQKTRSAVIVLQSAYR 1644
+MK+AAV IQ +R+Y +V + ++T++AV LQ+++R
Sbjct: 978 -------------------QMKRAAVTIQACWRSY----RVRRALERTQAAV-YLQASWR 1013
Query: 1645 GMQARKMYIHILTSVIKIQSYYRAYVSKKEF 1675
G RK+Y H S+I++QS R ++ +K F
Sbjct: 1014 GYWQRKLYRHQKQSIIRLQSLCRGHLQRKSF 1044
Score = 55.5 bits (132), Expect = 9e-07
Identities = 35/130 (26%), Positives = 67/130 (51%), Gaps = 5/130 (3%)
Query: 1476 RMHKELRKYIYIRSCVVIIQKRFRCFQAQKLYKRRKESILTIQKYYKAYLKGKIERTNYL 1535
+M + R Y I V +++ R + L++ IL +Q +++ L ER ++L
Sbjct: 923 KMKIDKRNY-QIGKTKVFLKETERQALQETLHREVVRKILLLQSWFRMVL----ERRHFL 977
Query: 1536 QKRAAAIQLQAAFRRLKAHNLCRQIRAACVIQSYWRMRQDRVRFLNLKKTIIKFQAHVRK 1595
Q + AA+ +QA +R + + +AA +Q+ WR R + + K++II+ Q+ R
Sbjct: 978 QMKRAAVTIQACWRSYRVRRALERTQAAVYLQASWRGYWQRKLYRHQKQSIIRLQSLCRG 1037
Query: 1596 HQQRQKYKKM 1605
H QR+ + +M
Sbjct: 1038 HLQRKSFSQM 1047
Score = 52.0 bits (123), Expect = 1e-05
Identities = 56/277 (20%), Positives = 119/277 (42%), Gaps = 28/277 (10%)
Query: 1659 VIKIQSYYRAYVSKKEFLSLKNATIKLQSTVKMKQTRKQYLHLRAAALFIQQCYRSKKIA 1718
++K + + + K L K+ + + T+ +T K LHL + I+
Sbjct: 777 ILKSKGIKQKQIIPKNLLDSKSLKLIISMTLH-DRTTKSLLHLHKKK-------KPPSIS 828
Query: 1719 AQKREEYMQMRESCIKLQAF----VRGYLVRKQMRLQRKAVISLQSYFRMRKARQYYLKM 1774
AQ + ++ E+ K + F +R +K++ + V+ Y M + +
Sbjct: 829 AQFQTSLNKLLEALGKAEPFFIRCIRSNAEKKELCFDDELVLQQLRYTGMLETVRIRRSG 888
Query: 1775 YKAIIVIQNYYHAYKAQVNQRKNFLQVKKAATC---LQAAYRGYKVRQLIKQQSIAALKI 1831
Y A Q++ ++ L K A C + K+ + Q + +
Sbjct: 889 YSAKYTFQDFTEQFQV--------LLPKDAQPCREVISTLLEKMKIDKRNYQIGKTKVFL 940
Query: 1832 QSAFRGYNKRVKYQSVLQSIIKIQRWYRAYKTLHDTRTHFLKTKAAVISLQSAYRGWKVR 1891
+ R + ++ V++ I+ +Q W+R R HFL+ K A +++Q+ +R ++VR
Sbjct: 941 KETERQALQETLHREVVRKILLLQSWFRMVLE----RRHFLQMKRAAVTIQACWRSYRVR 996
Query: 1892 KQIRREHQAALKIQSAFRMAKAQKQFRLFKTAALVIQ 1928
+ + R QAA+ +Q+++R +K +R K + + +Q
Sbjct: 997 RALERT-QAAVYLQASWRGYWQRKLYRHQKQSIIRLQ 1032
Score = 52.0 bits (123), Expect = 1e-05
Identities = 41/164 (25%), Positives = 86/164 (52%), Gaps = 18/164 (10%)
Query: 2439 RKYRATICAKHKL----YQFLHLRKAAITIQSSYRRLMVKKKLQEMQRAAVLIQATFRMY 2494
R+ +T+ K K+ YQ + K + ++ + R+ + + +E+ R +L+Q+ FRM
Sbjct: 914 REVISTLLEKMKIDKRNYQ---IGKTKVFLKETERQALQETLHREVVRKILLLQSWFRMV 970
Query: 2495 RTYITFQTWKHASILIQQHYRTYRAAKLQRENYIRQWHSAVVIQAAYKGMKARQLLREKH 2554
F K A++ IQ +R+YR + + + +AV +QA+++G R+L R +
Sbjct: 971 LERRHFLQMKRAAVTIQACWRSYRVRRA-----LERTQAAVYLQASWRGYWQRKLYRHQK 1025
Query: 2555 KASIVIQSTYRMYRQYCFYQKLQWATKIIQEKYRANKKKQKVFQ 2598
++ I +QS R + Q + +++I EK +A +K+++ +
Sbjct: 1026 QSIIRLQSLCRGHLQRKSF------SQMISEKQKAEEKEREALE 1063
Score = 51.2 bits (121), Expect = 2e-05
Identities = 30/90 (33%), Positives = 51/90 (56%), Gaps = 5/90 (5%)
Query: 1685 LQSTVKMKQTRKQYLHLRAAALFIQQCYRSKKIAAQKREEYMQMRESCIKLQAFVRGYLV 1744
LQS +M R+ +L ++ AA+ IQ C+RS ++ ++ ++ + LQA RGY
Sbjct: 963 LQSWFRMVLERRHFLQMKRAAVTIQACWRSYRV-----RRALERTQAAVYLQASWRGYWQ 1017
Query: 1745 RKQMRLQRKAVISLQSYFRMRKARQYYLKM 1774
RK R Q++++I LQS R R+ + +M
Sbjct: 1018 RKLYRHQKQSIIRLQSLCRGHLQRKSFSQM 1047
Score = 50.8 bits (120), Expect = 2e-05
Identities = 30/104 (28%), Positives = 62/104 (59%), Gaps = 8/104 (7%)
Query: 1961 KTLRRQLQRQHKCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYRAYSIGREQNHLYLKT 2020
+TL R++ R+ +++QS++RM ++++ + MK+AA+ IQ +R+Y + R L+
Sbjct: 950 ETLHREVVRK---ILLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVRRA-----LER 1001
Query: 2021 KAAVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYA 2064
A V LQ+++RG RK + ++ + +QS R + +K ++
Sbjct: 1002 TQAAVYLQASWRGYWQRKLYRHQKQSIIRLQSLCRGHLQRKSFS 1045
Score = 48.5 bits (114), Expect = 1e-04
Identities = 36/135 (26%), Positives = 69/135 (51%), Gaps = 10/135 (7%)
Query: 1982 RMHVQQKKWKIMKKAALLIQKYYRAYSIGREQNHLYLKTKAAVVTLQSAYRGMKVRKRIK 2041
+M + ++ ++I K L + +A Q L+ + ++ LQS +R + R+
Sbjct: 923 KMKIDKRNYQIGKTKVFLKETERQAL-----QETLHREVVRKILLLQSWFRMVLERRHFL 977
Query: 2042 DCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKITNHQHKEYLNLKKTAIKIQ 2101
+AAVTIQ+ +R+Y+ ++ +A A+ +Q +RG Q K Y + K++ I++Q
Sbjct: 978 QMKRAAVTIQACWRSYRVRRALERTQA-AVYLQASWRGY----WQRKLYRHQKQSIIRLQ 1032
Query: 2102 SVYRGIRVRRHIQHM 2116
S+ RG R+ M
Sbjct: 1033 SLCRGHLQRKSFSQM 1047
Score = 48.5 bits (114), Expect = 1e-04
Identities = 28/116 (24%), Positives = 60/116 (51%)
Query: 2902 QRQVYLQIRSSVIIIQARSKGFIQKRKFQEIKNSTIKIQAMWRRYRAKKYLCKVKAACKI 2961
Q ++ ++ ++++Q+ + +++R F ++K + + IQA WR YR ++ L + +AA +
Sbjct: 949 QETLHREVVRKILLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVRRALERTQAAVYL 1008
Query: 2962 QAWYRCWRAHKEYLAILKAVKIIQGCFYTKLERTRFLNVRASAIIIQRKWRAILPA 3017
QA +R + K Y +++ +Q L+R F + + + K R L A
Sbjct: 1009 QASWRGYWQRKLYRHQKQSIIRLQSLCRGHLQRKSFSQMISEKQKAEEKEREALEA 1064
Score = 47.8 bits (112), Expect = 2e-04
Identities = 30/92 (32%), Positives = 48/92 (52%), Gaps = 5/92 (5%)
Query: 1902 LKIQSAFRMAKAQKQFRLFKTAALVIQQNFRAWTAGRKQCMEYIELRHAVLVLQSMWKGK 1961
L +QS FRM ++ F K AA+ IQ +R++ R +E A + LQ+ W+G
Sbjct: 961 LLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVRRA-----LERTQAAVYLQASWRGY 1015
Query: 1962 TLRRQLQRQHKCAIIIQSYYRMHVQQKKWKIM 1993
R+ + Q + I +QS R H+Q+K + M
Sbjct: 1016 WQRKLYRHQKQSIIRLQSLCRGHLQRKSFSQM 1047
Score = 47.4 bits (111), Expect = 3e-04
Identities = 27/94 (28%), Positives = 51/94 (54%), Gaps = 10/94 (10%)
Query: 2971 HKEYLAILKAVKIIQGCFYTKLERTRFLNVRASAIIIQRKWRAILPAKIAHEHFLMIKRH 3030
H+E +++ + ++Q F LER FL ++ +A+ IQ WR+ + ++R
Sbjct: 953 HRE---VVRKILLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVRRA-------LERT 1002
Query: 3031 RAACLIQAHYRGYKGRQVFLRQKSAALIIQKYIR 3064
+AA +QA +RGY R+++ QK + + +Q R
Sbjct: 1003 QAAVYLQASWRGYWQRKLYRHQKQSIIRLQSLCR 1036
Score = 47.0 bits (110), Expect = 3e-04
Identities = 41/163 (25%), Positives = 76/163 (46%), Gaps = 12/163 (7%)
Query: 2264 IAATLIQRRFRTLMMRRRFLSLKKTAILIQRKYRAHLCTKHHLQFLQVQNAVIKIQSSYR 2323
+ +TL+++ + + +R + KT + ++ R L H + V ++ +QS +R
Sbjct: 916 VISTLLEK----MKIDKRNYQIGKTKVFLKETERQALQETLHRE---VVRKILLLQSWFR 968
Query: 2324 RWMIRKRMREMHRAATFIQSTFRMHRLHMRYQALKQASVVIQQQYQANRAAKLQRQHYLR 2383
+ R+ +M RAA IQ+ +R +R+ R QA+V +Q ++ QR+ Y
Sbjct: 969 MVLERRHFLQMKRAAVTIQACWRSYRVR-RALERTQAAVYLQASWR----GYWQRKLYRH 1023
Query: 2384 QRHSAVILQAAFRGMKTRRHLKSMHSSATLIQSRFRSLLVRRR 2426
Q+ S + LQ+ RG R+ M S + + R L R
Sbjct: 1024 QKQSIIRLQSLCRGHLQRKSFSQMISEKQKAEEKEREALEAAR 1066
Score = 46.6 bits (109), Expect = 4e-04
Identities = 29/126 (23%), Positives = 62/126 (49%), Gaps = 7/126 (5%)
Query: 1426 IIQSMFRKWKQRKMQSQVKATVILQRAFREWHLRKQAKEE--NSAIIIQSWYRMHKELRK 1483
+I ++ K K K Q+ T + + L++ E +++QSW+RM E R
Sbjct: 916 VISTLLEKMKIDKRNYQIGKTKVFLKETERQALQETLHREVVRKILLLQSWFRMVLERRH 975
Query: 1484 YIYIRSCVVIIQKRFRCFQAQKLYKRRKESILTIQKYYKAYLKGKIERTNYLQKRAAAIQ 1543
++ ++ V IQ +R ++ ++ +R + ++ Y +A +G +R Y ++ + I+
Sbjct: 976 FLQMKRAAVTIQACWRSYRVRRALERTQAAV-----YLQASWRGYWQRKLYRHQKQSIIR 1030
Query: 1544 LQAAFR 1549
LQ+ R
Sbjct: 1031 LQSLCR 1036
Score = 45.1 bits (105), Expect = 0.001
Identities = 36/152 (23%), Positives = 73/152 (48%), Gaps = 12/152 (7%)
Query: 2038 KRIKDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKITNHQHKEYLNLKKTA 2097
K + C + T+ K + K+ Y + + + + ++ T H+ + +
Sbjct: 908 KDAQPCREVISTLLEKMKI--DKRNYQIGKTKVFLKETERQALQETLHRE-----VVRKI 960
Query: 2098 IKIQSVYRGIRVRRHIQHMHRAATFIKAMFKMHQSRISYHTMRKAAIVIQVRCRAYYQGK 2157
+ +QS +R + RRH M RAA I+A ++ ++ R + +AA+ +Q R Y+Q K
Sbjct: 961 LLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVRRALE-RTQAAVYLQASWRGYWQRK 1019
Query: 2158 MQREKYLTILKAVKVLQASFRGVRVRRTLRKM 2189
+ R + +I++ LQ+ RG R++ +M
Sbjct: 1020 LYRHQKQSIIR----LQSLCRGHLQRKSFSQM 1047
Score = 43.1 bits (100), Expect = 0.005
Identities = 31/146 (21%), Positives = 76/146 (52%), Gaps = 2/146 (1%)
Query: 1409 RRKQDQQRYEMLKSSTLIIQSMFRKWKQRKMQSQVKATVILQRAFREWHLRKQAKE-ENS 1467
+ K D++ Y++ K+ + ++ + ++ + V+ ++LQ FR R+ + + +
Sbjct: 923 KMKIDKRNYQIGKTKVFLKETERQALQETLHREVVRKILLLQSWFRMVLERRHFLQMKRA 982
Query: 1468 AIIIQSWYRMHKELRKYIYIRSCVVIIQKRFRCFQAQKLYKRRKESILTIQKYYKAYLKG 1527
A+ IQ+ +R ++ +R+ + V +Q +R + +KLY+ +K+SI+ +Q + +L+
Sbjct: 983 AVTIQACWRSYR-VRRALERTQAAVYLQASWRGYWQRKLYRHQKQSIIRLQSLCRGHLQR 1041
Query: 1528 KIERTNYLQKRAAAIQLQAAFRRLKA 1553
K +K+ A + + A +A
Sbjct: 1042 KSFSQMISEKQKAEEKEREALEAARA 1067
Score = 41.6 bits (96), Expect = 0.014
Identities = 35/168 (20%), Positives = 80/168 (47%), Gaps = 22/168 (13%)
Query: 2318 IQSSYRRWMIRKRMREMHRAATFIQSTFRMHRLHMRYQALKQASVVIQQQYQANRAAKLQ 2377
I + + I KR ++ + F++ T R ++ + + +++Q ++ L+
Sbjct: 917 ISTLLEKMKIDKRNYQIGKTKVFLKETERQALQETLHREVVRKILLLQSWFRM----VLE 972
Query: 2378 RQHYLRQRHSAVILQAAFRGMKTRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFV 2437
R+H+L+ + +AV +QA +R + RR L+ +A +Q+ +R R+ + K++ I +
Sbjct: 973 RRHFLQMKRAAVTIQACWRSYRVRRALERT-QAAVYLQASWRGYWQRKLYRHQKQSIIRL 1031
Query: 2438 QRKYRATICAKHKLYQFLHLRKAAITIQSSYRRLMVKKKLQEMQRAAV 2485
Q ++C H + +S + + K+K +E +R A+
Sbjct: 1032 Q-----SLCRGH------------LQRKSFSQMISEKQKAEEKEREAL 1062
Score = 41.6 bits (96), Expect = 0.014
Identities = 29/94 (30%), Positives = 41/94 (43%), Gaps = 19/94 (20%)
Query: 3141 VNSVICIQRWFRARLQEKRFIQKYHSIKKIEHEGQECLSQRNRAASVIQKAVRHFLLRKK 3200
V ++ +Q WFR L+ + F+ Q RAA IQ R + +R+
Sbjct: 957 VRKILLLQSWFRMVLERRHFL------------------QMKRAAVTIQACWRSYRVRRA 998
Query: 3201 QEKFTSGIIKIQALWRGYSWRKKNDCTKIKAIRL 3234
E+ T + +QA WRGY RK K IRL
Sbjct: 999 LER-TQAAVYLQASWRGYWQRKLYRHQKQSIIRL 1031
Score = 41.2 bits (95), Expect = 0.018
Identities = 31/104 (29%), Positives = 52/104 (50%), Gaps = 5/104 (4%)
Query: 1340 KEKLEKVQNKAASLIQGYWRRYSTRQRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVT 1399
+E L + + L+Q ++R R+ FL++K ++ +Q+ R + +R A V
Sbjct: 949 QETLHREVVRKILLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVRRALER-TQAAVY 1007
Query: 1400 IQRHWRAYLRRKQDQQRYEMLKSSTLIIQSMFRKWKQRKMQSQV 1443
+Q WR Y +RK Y K S + +QS+ R QRK SQ+
Sbjct: 1008 LQASWRGYWQRK----LYRHQKQSIIRLQSLCRGHLQRKSFSQM 1047
Score = 40.0 bits (92), Expect = 0.040
Identities = 40/165 (24%), Positives = 73/165 (44%), Gaps = 13/165 (7%)
Query: 2612 FQDMNIKKQI---QEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQRRYRK-----LTA 2663
FQD + Q+ ++ +I + KI K + T V ++ R+ L
Sbjct: 895 FQDFTEQFQVLLPKDAQPCREVISTLLEKMKIDKRNYQIGKTKVFLKETERQALQETLHR 954
Query: 2664 VRTQAVICIQSYYRGFKVRKDIQNMHRAATLIQSFYRMHRAKVDYETKKTAIVVIQNYYR 2723
+ ++ +QS++R R+ M RAA IQ+ +R +R + E + A V +Q +R
Sbjct: 955 EVVRKILLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVRRALE-RTQAAVYLQASWR 1013
Query: 2724 LYVRVKTERKNFLAVQKSVRTIQAAFRGMKVRQKLKNVSEEKMAA 2768
Y +RK + ++S+ +Q+ RG R+ + EK A
Sbjct: 1014 GY----WQRKLYRHQKQSIIRLQSLCRGHLQRKSFSQMISEKQKA 1054
Score = 39.7 bits (91), Expect = 0.053
Identities = 22/91 (24%), Positives = 48/91 (52%), Gaps = 1/91 (1%)
Query: 2124 KAMFKMHQSRISYHTMRKAAIVIQVRCRAYYQGKMQREKYLTILKAVKVLQASFRGVRVR 2183
K K + + T+ + + + +++++ ++R +L + +A +QA +R RVR
Sbjct: 937 KVFLKETERQALQETLHREVVRKILLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVR 996
Query: 2184 RTLRKMQTAATLIQSNYRRYRQQTYFNKLKK 2214
R L + Q AA +Q+++R Y Q+ + K+
Sbjct: 997 RALERTQ-AAVYLQASWRGYWQRKLYRHQKQ 1026
Score = 39.7 bits (91), Expect = 0.053
Identities = 33/114 (28%), Positives = 49/114 (42%), Gaps = 16/114 (14%)
Query: 3072 ERIKYIEFKKSTVILQALVRGWLVRKRFLEQRAKIRLLHFTAAAYYHLNAVRIQRAYKLY 3131
ER +++ K++ V +QA R + VR R L T AA Y +Q +++ Y
Sbjct: 972 ERRHFLQMKRAAVTIQACWRSYRVR----------RALERTQAAVY------LQASWRGY 1015
Query: 3132 LAVKNANKQVNSVICIQRWFRARLQEKRFIQKYHSIKKIEHEGQECLSQRNRAA 3185
K Q S+I +Q R LQ K F Q +K E + +E L A
Sbjct: 1016 WQRKLYRHQKQSIIRLQSLCRGHLQRKSFSQMISEKQKAEEKEREALEAARAGA 1069
Score = 39.3 bits (90), Expect = 0.069
Identities = 23/88 (26%), Positives = 48/88 (54%), Gaps = 5/88 (5%)
Query: 1375 IILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQRYEMLKSSTLIIQSMFRKW 1434
++LQS RM++ + + A VTIQ WR+Y R+ ++ + + +Q+ +R +
Sbjct: 961 LLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVRRALER-----TQAAVYLQASWRGY 1015
Query: 1435 KQRKMQSQVKATVILQRAFREWHLRKQA 1462
QRK+ K ++I ++ HL++++
Sbjct: 1016 WQRKLYRHQKQSIIRLQSLCRGHLQRKS 1043
Score = 37.7 bits (86), Expect = 0.20
Identities = 30/125 (24%), Positives = 58/125 (46%), Gaps = 5/125 (4%)
Query: 2088 KEYLNLKKTAIKIQSVYRGIRVRRHIQHMHRAATFIKAMFKMHQSRISYHTMRKAAIVIQ 2147
K + KT + ++ R + + R +++ F+M R + M++AA+ IQ
Sbjct: 928 KRNYQIGKTKVFLKETERQALQETLHREVVRKILLLQSWFRMVLERRHFLQMKRAAVTIQ 987
Query: 2148 VRCRAYYQGKMQREKYLTILKAVKVLQASFRGVRVRRTLRKMQTAATLIQSNYRRYRQQT 2207
R+Y + + L +A LQAS+RG R+ R + + +QS R + Q+
Sbjct: 988 ACWRSY-----RVRRALERTQAAVYLQASWRGYWQRKLYRHQKQSIIRLQSLCRGHLQRK 1042
Query: 2208 YFNKL 2212
F+++
Sbjct: 1043 SFSQM 1047
Score = 37.0 bits (84), Expect = 0.34
Identities = 27/104 (25%), Positives = 51/104 (49%), Gaps = 4/104 (3%)
Query: 2231 IQFQRYNKLRHSVIYIQAIFRGKKARRHLKMMHIAATLIQRRFRTLMMRRRFLSLKKTAI 2290
+Q + ++ ++ +Q+ FR RRH M AA IQ +R+ +RR L + A+
Sbjct: 948 LQETLHREVVRKILLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVRRA-LERTQAAV 1006
Query: 2291 LIQRKYRAHLCTKHHLQFLQVQNAVIKIQSSYRRWMIRKRMREM 2334
+Q +R + K + + ++I++QS R + RK +M
Sbjct: 1007 YLQASWRGYWQRK---LYRHQKQSIIRLQSLCRGHLQRKSFSQM 1047
Score = 36.2 bits (82), Expect = 0.58
Identities = 31/157 (19%), Positives = 72/157 (45%), Gaps = 16/157 (10%)
Query: 1571 RMRQDRVRFLNLKKTIIKFQAHVRKHQQRQKYKKMKKAAVIIQTHFRAYIFAMKVLASYQ 1630
+M+ D+ R + KT + + R+ Q ++++ + +++Q+ FR + L
Sbjct: 923 KMKIDK-RNYQIGKTKVFLKETERQALQETLHREVVRKILLLQSWFRMVLERRHFL---- 977
Query: 1631 KTRSAVIVLQSAYRGMQARKMYIHILTSVIKIQSYYRAYVSKKEFLSLKNATIKLQSTVK 1690
+ + A + +Q+ +R + R+ + + + +Q+ +R Y +K + K + I+LQS +
Sbjct: 978 QMKRAAVTIQACWRSYRVRRA-LERTQAAVYLQASWRGYWQRKLYRHQKQSIIRLQSLCR 1036
Query: 1691 MKQTRKQYLHLRAAALFIQQCYRSKKIAAQKREEYMQ 1727
RK + Q K+ A +K E ++
Sbjct: 1037 GHLQRKSF----------SQMISEKQKAEEKEREALE 1063
Score = 35.4 bits (80), Expect = 0.99
Identities = 22/81 (27%), Positives = 46/81 (56%), Gaps = 8/81 (9%)
Query: 2715 IVVIQNYYRLYVRVKTERKNFLAVQKSVRTIQAAFRGMKVRQKLKNVSEEKMAAIVNQSA 2774
I+++Q+++R+ + ER++FL ++++ TIQA +R +VR+ L E AA+ Q++
Sbjct: 960 ILLLQSWFRMVL----ERRHFLQMKRAAVTIQACWRSYRVRRAL----ERTQAAVYLQAS 1011
Query: 2775 LCCYRSKTQYEAVQSEGVMIQ 2795
Y + Y + + +Q
Sbjct: 1012 WRGYWQRKLYRHQKQSIIRLQ 1032
Score = 32.3 bits (72), Expect = 8.4
Identities = 29/103 (28%), Positives = 50/103 (48%), Gaps = 8/103 (7%)
Query: 1263 LRKEIRAARLIQTTWRKYKLKTDLKRHQEREKAARIIQLAVINFLAKQRLRKRVNAALVI 1322
L +E+ L+ +W + L+ +RH + K A + A +R +R AA+ +
Sbjct: 952 LHREVVRKILLLQSWFRMVLE---RRHFLQMKRAAVTIQACWRSYRVRRALERTQAAVYL 1008
Query: 1323 QKYWRRVLAQRKLLMLKKEKLEKVQNKAASLIQGYWRRYSTRQ 1365
Q WR QRKL +K+ + ++Q SL +G+ +R S Q
Sbjct: 1009 QASWRGYW-QRKLYRHQKQSIIRLQ----SLCRGHLQRKSFSQ 1046
>gi|194328685 myosin IB isoform 1 [Homo sapiens]
Length = 1136
Score = 58.9 bits (141), Expect = 8e-08
Identities = 46/168 (27%), Positives = 78/168 (46%), Gaps = 16/168 (9%)
Query: 1864 LHDTRTHFLKTKAAVISLQSAYRGWKVRKQIRREHQAALKIQSAFRMAKAQKQFRLFKTA 1923
L D R L+ A +I Q YRGWK R ++ + I + +R QK+++ K++
Sbjct: 696 LEDLRKQRLEDLATLI--QKIYRGWKCRTHFLLMKKSQIVIAAWYRRYAQQKRYQQTKSS 753
Query: 1924 ALVIQQNFRAWTAGR--KQCMEYIELRHAVLVLQSMWKGKTLRRQLQR-------QHKCA 1974
ALVIQ R W A + ++ + AV + + W G RR+L+R +H A
Sbjct: 754 ALVIQSYIRGWKARKILRELKHQKRCKEAVTTIAAYWHGTQARRELRRLKEEARNKHAIA 813
Query: 1975 II----IQSYYRMHVQQKKWKIMKK-AALLIQKYYRAYSIGREQNHLY 2017
+I + S R +++ K + +K A +I Y+ + RE +
Sbjct: 814 VIWAYWLGSKARRELKRLKEEARRKHAVAVIWAYWLGLKVRREYRKFF 861
Score = 55.8 bits (133), Expect = 7e-07
Identities = 56/199 (28%), Positives = 89/199 (44%), Gaps = 34/199 (17%)
Query: 2007 YSIGREQNHLYLKTKAAVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYATY 2066
YS GR + ++++ + L+ + +R++D A IQ YR +K + +
Sbjct: 678 YSFGRSK--IFIRNPRTLFKLEDLRK-----QRLEDL---ATLIQKIYRGWKCRTHFLLM 727
Query: 2067 RASAIIIQRWYRGIKITNHQHKEYLNLKKTAIKIQSVYRGIRVR---RHIQHMHR---AA 2120
+ S I+I WYR Q K Y K +A+ IQS RG + R R ++H R A
Sbjct: 728 KKSQIVIAAWYRRYA----QQKRYQQTKSSALVIQSYIRGWKARKILRELKHQKRCKEAV 783
Query: 2121 TFIKAMFKMHQS-----RISYHTMRKAAIVIQVRCRAYYQGKMQREKYLTILK------A 2169
T I A + Q+ R+ K AI + AY+ G R + + + A
Sbjct: 784 TTIAAYWHGTQARRELRRLKEEARNKHAIAV---IWAYWLGSKARRELKRLKEEARRKHA 840
Query: 2170 VKVLQASFRGVRVRRTLRK 2188
V V+ A + G++VRR RK
Sbjct: 841 VAVIWAYWLGLKVRREYRK 859
Score = 55.8 bits (133), Expect = 7e-07
Identities = 78/336 (23%), Positives = 134/336 (39%), Gaps = 109/336 (32%)
Query: 1334 KLLMLKKEKLEKVQNKAASLIQGYWRRYSTRQRFLKLKYYSIILQSRIRMIIAVTSYKRY 1393
KL L+K++LE + A+LIQ +R + R FL +K I++
Sbjct: 695 KLEDLRKQRLEDL----ATLIQKIYRGWKCRTHFLLMKKSQIVIA--------------- 735
Query: 1394 LWATVTIQRHWRAYLRRKQDQQRYEMLKSSTLIIQSMFRKWKQRKM------QSQVKATV 1447
A+ RR Q+RY+ KSS L+IQS R WK RK+ Q + K V
Sbjct: 736 ------------AWYRRYAQQKRYQQTKSSALVIQSYIRGWKARKILRELKHQKRCKEAV 783
Query: 1448 ILQRAFREWH----------LRKQAKEENSAIIIQSWY------RMHKELRKYIYIRSCV 1491
A+ WH L+++A+ +++ +I +++ R K L++ + V
Sbjct: 784 TTIAAY--WHGTQARRELRRLKEEARNKHAIAVIWAYWLGSKARRELKRLKEEARRKHAV 841
Query: 1492 VII-------------QKRFRCFQAQKLYKRRKESILTIQKYYKAYLKGKIERTNYLQKR 1538
+I +K FR +K+Y+ + I +QKY+ +K K+ + + K
Sbjct: 842 AVIWAYWLGLKVRREYRKFFRANAGKKIYEFTLQRI--VQKYF-LEMKNKMPSLSPIDKN 898
Query: 1539 AAA---IQLQAAFRRLKAHNLCRQIRAACVIQSYWRMRQDRVRFLNLKKTIIK------- 1588
+ + L + + LK I WR ++ R +F + +K I +
Sbjct: 899 WPSRPYLFLDSTHKELKR------------IFHLWRCKKYRDQFTDQQKLIYEEKLEASE 946
Query: 1589 ----------------FQAHVRKHQQRQKYKKMKKA 1608
FQ + + KYKK+K A
Sbjct: 947 LFKDKKALYPSSVGQPFQGAYLEINKNPKYKKLKDA 982
Score = 52.0 bits (123), Expect = 1e-05
Identities = 58/252 (23%), Positives = 98/252 (38%), Gaps = 47/252 (18%)
Query: 2093 LKKTAIKIQSVYRGIRVRRHIQHMHRAATFIKAMFKMHQSRISYHTMRKAAIVIQVRCRA 2152
L+ A IQ +YRG + R H M ++ I A ++ + + Y + +A+VIQ R
Sbjct: 704 LEDLATLIQKIYRGWKCRTHFLLMKKSQIVIAAWYRRYAQQKRYQQTKSSALVIQSYIRG 763
Query: 2153 YYQGKMQRE-KYLTILK-AVKVLQASFRGVRVRRTLRKMQTAATLIQSNYRRYRQQTYFN 2210
+ K+ RE K+ K AV + A + G + RR LR+++ A
Sbjct: 764 WKARKILRELKHQKRCKEAVTTIAAYWHGTQARRELRRLKEEAR---------------- 807
Query: 2211 KLKKITKTVQQRYWAMKERNIQFQRYN---KLRHSVIYIQAIFRGKKARRHLKMMHIA-- 2265
K V YW + + +R + +H+V I A + G K RR + A
Sbjct: 808 --NKHAIAVIWAYWLGSKARRELKRLKEEARRKHAVAVIWAYWLGLKVRREYRKFFRANA 865
Query: 2266 ---------ATLIQRRFRTLMMR-------------RRFLSLKKTAILIQRKYRAHLCTK 2303
++Q+ F + + R +L L T ++R + C K
Sbjct: 866 GKKIYEFTLQRIVQKYFLEMKNKMPSLSPIDKNWPSRPYLFLDSTHKELKRIFHLWRCKK 925
Query: 2304 HHLQFLQVQNAV 2315
+ QF Q +
Sbjct: 926 YRDQFTDQQKLI 937
Score = 51.2 bits (121), Expect = 2e-05
Identities = 29/95 (30%), Positives = 55/95 (57%), Gaps = 2/95 (2%)
Query: 2672 IQSYYRGFKVRKDIQNMHRAATLIQSFYRMHRAKVDYETKKTAIVVIQNYYRLYV--RVK 2729
IQ YRG+K R M ++ +I ++YR + + Y+ K++ +VIQ+Y R + ++
Sbjct: 711 IQKIYRGWKCRTHFLLMKKSQIVIAAWYRRYAQQKRYQQTKSSALVIQSYIRGWKARKIL 770
Query: 2730 TERKNFLAVQKSVRTIQAAFRGMKVRQKLKNVSEE 2764
E K+ +++V TI A + G + R++L+ + EE
Sbjct: 771 RELKHQKRCKEAVTTIAAYWHGTQARRELRRLKEE 805
Score = 50.8 bits (120), Expect = 2e-05
Identities = 59/254 (23%), Positives = 112/254 (44%), Gaps = 24/254 (9%)
Query: 2451 LYQFLHLRKAAITIQSSYRRLMVKKKLQEMQR-------AAVLIQATFRMYRTYITFQTW 2503
L + + +R+A + +Y + + K+ Q A ++ F + ++
Sbjct: 621 LLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPARSGVEVLFNELEIPVEEYSF 680
Query: 2504 KHASILIQQHYRTYRAAKLQRENYIRQWHSAVVIQAAYKGMKARQLLREKHKASIVIQST 2563
+ I I+ ++ L+++ R A +IQ Y+G K R K+ IVI +
Sbjct: 681 GRSKIFIRNPRTLFKLEDLRKQ---RLEDLATLIQKIYRGWKCRTHFLLMKKSQIVIAAW 737
Query: 2564 YRMYRQYCFYQKLQWATKIIQEKYRANKKKQ--KVFQHNELKKE--TCVQAGFQDMNIKK 2619
YR Y Q YQ+ + + +IQ R K ++ + +H + KE T + A + ++
Sbjct: 738 YRRYAQQKRYQQTKSSALVIQSYIRGWKARKILRELKHQKRCKEAVTTIAAYWHGTQARR 797
Query: 2620 QIQEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQRRYRKL--TAVRTQAVICIQSYYR 2677
+++ + A KH A I ++L +A +R ++L A R AV I +Y+
Sbjct: 798 ELRRLKEEA--RNKHAIAV-IWAYWLGSKA-----RRELKRLKEEARRKHAVAVIWAYWL 849
Query: 2678 GFKVRKDIQNMHRA 2691
G KVR++ + RA
Sbjct: 850 GLKVRREYRKFFRA 863
Score = 49.3 bits (116), Expect = 7e-05
Identities = 54/224 (24%), Positives = 90/224 (40%), Gaps = 55/224 (24%)
Query: 2235 RYNKLRHSVIYIQAIFRGKKARRHLKMMHIAATLIQRRFRTLMMRRRFLSLKKTAILIQR 2294
R +L IQ I+RG K R H FL +KK+ I+I
Sbjct: 700 RKQRLEDLATLIQKIYRGWKCRTH-----------------------FLLMKKSQIVIAA 736
Query: 2295 KYRAHLCTKHHLQFLQVQNAVIKIQSSYRRWMIRKRMREMHRAATFIQSTFRMHRLHMRY 2354
YR + K ++ Q +++ + IQS R W RK +RE+
Sbjct: 737 WYRRYAQQK---RYQQTKSSALVIQSYIRGWKARKILREL-----------------KHQ 776
Query: 2355 QALKQASVVIQQQYQANRAAKLQR--QHYLRQRHSAVILQAAFRGMKTRRHLKSMHSSAT 2412
+ K+A I + +A + R + R +H+ ++ A + G K RR LK + A
Sbjct: 777 KRCKEAVTTIAAYWHGTQARRELRRLKEEARNKHAIAVIWAYWLGSKARRELKRLKEEA- 835
Query: 2413 LIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAK--HKLYQF 2454
+ + ++ ++ LK V+R+YR A K+Y+F
Sbjct: 836 --RRKHAVAVIWAYWLGLK-----VRREYRKFFRANAGKKIYEF 872
Score = 48.9 bits (115), Expect = 9e-05
Identities = 28/100 (28%), Positives = 55/100 (55%), Gaps = 10/100 (10%)
Query: 2863 AITLQHYFRTWQTRKQFLLYRKAAVVLQNHYRAFLSAKHQRQVYLQIRSSVIIIQARSKG 2922
A +Q +R W+ R FLL +K+ +V+ YR + Q++ Y Q +SS ++IQ+ +G
Sbjct: 708 ATLIQKIYRGWKCRTHFLLMKKSQIVIAAWYRRYA----QQKRYQQTKSSALVIQSYIRG 763
Query: 2923 FIQKRKFQEIKN------STIKIQAMWRRYRAKKYLCKVK 2956
+ ++ +E+K+ + I A W +A++ L ++K
Sbjct: 764 WKARKILRELKHQKRCKEAVTTIAAYWHGTQARRELRRLK 803
Score = 48.1 bits (113), Expect = 1e-04
Identities = 62/292 (21%), Positives = 118/292 (40%), Gaps = 67/292 (22%)
Query: 1630 QKTRSAVIVLQSAYRGMQARKMYIHILTSVIKIQSYYRAYVSKKEFLSLKNATIKLQSTV 1689
Q+ ++Q YRG + R ++ + S I I ++YR Y +K + K++ + +QS +
Sbjct: 702 QRLEDLATLIQKIYRGWKCRTHFLLMKKSQIVIAAWYRRYAQQKRYQQTKSSALVIQSYI 761
Query: 1690 KMKQTRKQYLHLRAAALFIQQCYRSKKIAAQKREEYMQMRESCIKLQAFVRGYLVRKQMR 1749
+ + RK +++ QKR +E+ + A+ G R+++R
Sbjct: 762 RGWKARKIL----------------RELKHQKR-----CKEAVTTIAAYWHGTQARRELR 800
Query: 1750 LQRKAVISLQSYFRMRKARQYYLKMYKAIIVIQNYYHAYKA--QVNQRKNFLQVKKAATC 1807
++ +AR + AI VI Y+ KA ++ + K + K A
Sbjct: 801 RLKE------------EARNKH-----AIAVIWAYWLGSKARRELKRLKEEARRKHAVAV 843
Query: 1808 LQAAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRVKYQSVLQSIIKIQRWYRAYKTLHDT 1867
+ A + G KVR+ + + FR + Y+ LQ I+
Sbjct: 844 IWAYWLGLKVRR----------EYRKFFRANAGKKIYEFTLQRIV--------------- 878
Query: 1868 RTHFLKTKAAVISLQSAYRGWKVRKQIRRE--HQAALKIQSAFRMAKAQKQF 1917
+ +FL+ K + SL + W R + + H+ +I +R K + QF
Sbjct: 879 QKYFLEMKNKMPSLSPIDKNWPSRPYLFLDSTHKELKRIFHLWRCKKYRDQF 930
Score = 47.4 bits (111), Expect = 3e-04
Identities = 26/90 (28%), Positives = 53/90 (58%), Gaps = 2/90 (2%)
Query: 1563 ACVIQSYWRMRQDRVRFLNLKKTIIKFQAHVRKHQQRQKYKKMKKAAVIIQTHFRAYIF- 1621
A +IQ +R + R FL +KK+ I A R++ Q+++Y++ K +A++IQ++ R +
Sbjct: 708 ATLIQKIYRGWKCRTHFLLMKKSQIVIAAWYRRYAQQKRYQQTKSSALVIQSYIRGWKAR 767
Query: 1622 -AMKVLASYQKTRSAVIVLQSAYRGMQARK 1650
++ L ++ + AV + + + G QAR+
Sbjct: 768 KILRELKHQKRCKEAVTTIAAYWHGTQARR 797
Score = 47.0 bits (110), Expect = 3e-04
Identities = 46/166 (27%), Positives = 74/166 (44%), Gaps = 19/166 (11%)
Query: 2187 RKMQTAATLIQSNYRRYRQQTYFNKLKKITKTVQQRYWAMKERNIQFQRYNKLRHSVIYI 2246
++++ ATLIQ YR ++ +T+F +KK + Y R Q +RY + + S + I
Sbjct: 702 QRLEDLATLIQKIYRGWKCRTHFLLMKKSQIVIAAWY----RRYAQQKRYQQTKSSALVI 757
Query: 2247 QAIFRGKKAR------RHLKMMHIAATLIQRRFRTLMMRRRFLSLK-----KTAILIQRK 2295
Q+ RG KAR +H K A T I + RR LK K AI +
Sbjct: 758 QSYIRGWKARKILRELKHQKRCKEAVTTIAAYWHGTQARRELRRLKEEARNKHAIAVIWA 817
Query: 2296 YRAHLCTKHHLQFLQVQ----NAVIKIQSSYRRWMIRKRMREMHRA 2337
Y + L+ L+ + +AV I + + +R+ R+ RA
Sbjct: 818 YWLGSKARRELKRLKEEARRKHAVAVIWAYWLGLKVRREYRKFFRA 863
Score = 46.2 bits (108), Expect = 6e-04
Identities = 64/248 (25%), Positives = 112/248 (45%), Gaps = 35/248 (14%)
Query: 1259 RLLDLRKEIRA--ARLIQTTWRKYKLKTDLKRHQEREKAARIIQLAVINFLAKQ-RLRKR 1315
+L DLRK+ A LIQ +R +K +T H K ++I+ A A+Q R ++
Sbjct: 695 KLEDLRKQRLEDLATLIQKIYRGWKCRT----HFLLMKKSQIVIAAWYRRYAQQKRYQQT 750
Query: 1316 VNAALVIQKYWRRVLAQRKLLMLKKEKLEKVQNKAASLIQGYWRRYSTRQRFLKLKYYSI 1375
++ALVIQ Y R A++ L LK +K K +A + I YW R+ +LK
Sbjct: 751 KSSALVIQSYIRGWKARKILRELKHQKRCK---EAVTTIAAYWHGTQARRELRRLKE--- 804
Query: 1376 ILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQRYEMLKS-----STLIIQSM 1430
++R + IAV +WA + R R K++ +R + L ++
Sbjct: 805 --EARNKHAIAV------IWAYWLGSKARRELKRLKEEARRKHAVAVIWAYWLGLKVRRE 856
Query: 1431 FRKWKQRKMQSQVKATVILQRAFREWHLRKQAKEENSAIIIQSW--------YRMHKELR 1482
+RK+ + ++ LQR +++ L + K + + I ++W HKEL+
Sbjct: 857 YRKFFRANAGKKI-YEFTLQRIVQKYFLEMKNKMPSLSPIDKNWPSRPYLFLDSTHKELK 915
Query: 1483 KYIYIRSC 1490
+ ++ C
Sbjct: 916 RIFHLWRC 923
Score = 45.4 bits (106), Expect = 0.001
Identities = 58/236 (24%), Positives = 106/236 (44%), Gaps = 42/236 (17%)
Query: 2870 FRTWQTRKQFLLYRKAAVVLQNHYRAFLSAKHQRQVYLQIRSSVIIIQARSKGFIQKRKF 2929
F+ RKQ L A ++Q YR + H +L ++ S I+I A + + Q++++
Sbjct: 694 FKLEDLRKQRL--EDLATLIQKIYRGWKCRTH----FLLMKKSQIVIAAWYRRYAQQKRY 747
Query: 2930 QEIKNSTIKIQAMWRRYRAKKYLCKVK-------AACKIQAWYRCWRAHKEYLAILKAVK 2982
Q+ K+S + IQ+ R ++A+K L ++K A I A++ +A +E L+ +K
Sbjct: 748 QQTKSSALVIQSYIRGWKARKILRELKHQKRCKEAVTTIAAYWHGTQARRE----LRRLK 803
Query: 2983 IIQGCFYTKLERTRFLNVRASAIIIQRKWRAILPAKIAHEHFLM---IKRHRAACLIQAH 3039
E R N A A+I W L +K E + +R A +I A+
Sbjct: 804 ----------EEAR--NKHAIAVI----WAYWLGSKARRELKRLKEEARRKHAVAVIWAY 847
Query: 3040 YRGYKGRQVFLR--QKSAALIIQKYIRAREAGKHERIKYIEFKKSTVILQALVRGW 3093
+ G K R+ + + + +A I ++ R K+ ++E K L + + W
Sbjct: 848 WLGLKVRREYRKFFRANAGKKIYEFTLQRIVQKY----FLEMKNKMPSLSPIDKNW 899
Score = 43.1 bits (100), Expect = 0.005
Identities = 42/187 (22%), Positives = 81/187 (43%), Gaps = 21/187 (11%)
Query: 2375 KLQRQHYLRQRHSAVILQAAFRGMKTRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKAT 2434
KL+ R A ++Q +RG K R H M S +I + +R ++R+ K +
Sbjct: 695 KLEDLRKQRLEDLATLIQKIYRGWKCRTHFLLMKKSQIVIAAWYRRYAQQKRYQQTKSSA 754
Query: 2435 IFVQRKYRATICAK--HKLYQFLHLRKAAITIQSSYRRLMVKKKLQEMQRAAVLIQATFR 2492
+ +Q R K +L ++A TI + + +++L+ ++ A
Sbjct: 755 LVIQSYIRGWKARKILRELKHQKRCKEAVTTIAAYWHGTQARRELRRLKEEA-------- 806
Query: 2493 MYRTYITFQTWKHASILIQQHYRTYRAAK-LQR-ENYIRQWHSAVVIQAAYKGMKARQLL 2550
KHA +I ++ +A + L+R + R+ H+ VI A + G+K R+
Sbjct: 807 ---------RNKHAIAVIWAYWLGSKARRELKRLKEEARRKHAVAVIWAYWLGLKVRREY 857
Query: 2551 REKHKAS 2557
R+ +A+
Sbjct: 858 RKFFRAN 864
Score = 43.1 bits (100), Expect = 0.005
Identities = 43/210 (20%), Positives = 83/210 (39%), Gaps = 18/210 (8%)
Query: 2686 QNMHRAATLIQSFYRMHRAKVDYETKKTAIVVIQNYYRLYVRVKTERKNFLAVQKSVRTI 2745
Q + ATLIQ YR + + + K + +VI +YR Y ++K + + S I
Sbjct: 702 QRLEDLATLIQKIYRGWKCRTHFLLMKKSQIVIAAWYRRY----AQQKRYQQTKSSALVI 757
Query: 2746 QAAFRGMKVRQKLKNVSEEKMAAIV----------NQSALCCYRSKTQYEAVQSEGVMIQ 2795
Q+ RG K R+ L+ + +K Q+ R K + + V+
Sbjct: 758 QSYIRGWKARKILRELKHQKRCKEAVTTIAAYWHGTQARRELRRLKEEARNKHAIAVIWA 817
Query: 2796 EWYKASGLACSQEAEYHSQSRAAVTIQKAFCRMVTRKLETQKC----AALRIQFFLQMAV 2851
W + + + ++ + AV + A+ + + E +K A +I F +
Sbjct: 818 YWLGSKARRELKRLKEEARRKHAVAVIWAYWLGLKVRREYRKFFRANAGKKIYEFTLQRI 877
Query: 2852 YRRRFVQQKRAAITLQHYFRTWQTRKQFLL 2881
++ F++ K +L + W +R L
Sbjct: 878 VQKYFLEMKNKMPSLSPIDKNWPSRPYLFL 907
Score = 42.7 bits (99), Expect = 0.006
Identities = 42/155 (27%), Positives = 70/155 (45%), Gaps = 34/155 (21%)
Query: 2622 QEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQRRYRKLTAVRTQAVICIQSYYRGFKV 2681
Q A +IQK + +K R H+L ++ ++ I I ++YR +
Sbjct: 702 QRLEDLATLIQKIYRGWKCRTHFLLMK------------------KSQIVIAAWYRRYAQ 743
Query: 2682 RKDIQNMHRAATLIQSFYRMHRA-KVDYETK-----KTAIVVIQNYY------RLYVRVK 2729
+K Q +A +IQS+ R +A K+ E K K A+ I Y+ R R+K
Sbjct: 744 QKRYQQTKSSALVIQSYIRGWKARKILRELKHQKRCKEAVTTIAAYWHGTQARRELRRLK 803
Query: 2730 TERKNFLAVQKSVRTIQAAFRGMKVRQKLKNVSEE 2764
E +N + ++ I A + G K R++LK + EE
Sbjct: 804 EEARN----KHAIAVIWAYWLGSKARRELKRLKEE 834
Score = 40.8 bits (94), Expect = 0.024
Identities = 41/179 (22%), Positives = 72/179 (40%), Gaps = 26/179 (14%)
Query: 1277 WRKYKLKTDLKRHQEREKAARIIQLAVINFLAKQRLRK------RVNAALVIQKYWRRVL 1330
W+ K+ +LK + ++A I A++ LR+ +A VI YW
Sbjct: 764 WKARKILRELKHQKRCKEAVTTIAAYWHGTQARRELRRLKEEARNKHAIAVIWAYWLGSK 823
Query: 1331 AQRKLLMLKKEKLEKVQNKAASLIQGYWRRYSTRQRFLKL-------KYYSIILQSRIRM 1383
A+R+L LK+E K A ++I YW R+ + K K Y LQ ++
Sbjct: 824 ARRELKRLKEEARRK---HAVAVIWAYWLGLKVRREYRKFFRANAGKKIYEFTLQRIVQK 880
Query: 1384 IIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQRYEMLKSSTLIIQSMFRKWKQRKMQSQ 1442
K + + I ++W + Y L S+ ++ +F W+ +K + Q
Sbjct: 881 YF--LEMKNKMPSLSPIDKNW--------PSRPYLFLDSTHKELKRIFHLWRCKKYRDQ 929
Score = 40.4 bits (93), Expect = 0.031
Identities = 43/185 (23%), Positives = 83/185 (44%), Gaps = 29/185 (15%)
Query: 1599 RQKYKKMKKAAVIIQTHFRAYIFAMKVLASYQKTRSAVIVLQSAYRGMQARKMYIHI--- 1655
R + MKK+ ++I +R Y + YQ+T+S+ +V+QS RG +ARK+ +
Sbjct: 721 RTHFLLMKKSQIVIAAWYRRYAQQKR----YQQTKSSALVIQSYIRGWKARKILRELKHQ 776
Query: 1656 ---LTSVIKIQSYYRAYVSKKEFLSLKNATIKLQSTVKMKQTRKQYLHLRAAALFIQQCY 1712
+V I +Y+ +++E LK ++ R ++ A A+
Sbjct: 777 KRCKEAVTTIAAYWHGTQARRELRRLK------------EEARNKH----AIAVIWAYWL 820
Query: 1713 RSKKIAAQKR-EEYMQMRESCIKLQAFVRGYLVRKQMR--LQRKAVISLQSYFRMRKARQ 1769
SK KR +E + + + + A+ G VR++ R + A + + R ++
Sbjct: 821 GSKARRELKRLKEEARRKHAVAVIWAYWLGLKVRREYRKFFRANAGKKIYEFTLQRIVQK 880
Query: 1770 YYLKM 1774
Y+L+M
Sbjct: 881 YFLEM 885
Score = 33.1 bits (74), Expect = 4.9
Identities = 45/236 (19%), Positives = 97/236 (41%), Gaps = 25/236 (10%)
Query: 2757 KLKNVSEEKMA--AIVNQSALCCYRSKTQYEAVQSEGVMIQEWYKASGLACSQEAEYHSQ 2814
KL+++ ++++ A + Q ++ +T + ++ ++I WY+ +Q+ Y
Sbjct: 695 KLEDLRKQRLEDLATLIQKIYRGWKCRTHFLLMKKSQIVIAAWYRRY----AQQKRYQQT 750
Query: 2815 SRAAVTIQKAF----CRMVTRKLETQK-C--AALRIQFFLQMAVYRRRF------VQQKR 2861
+A+ IQ R + R+L+ QK C A I + RR + K
Sbjct: 751 KSSALVIQSYIRGWKARKILRELKHQKRCKEAVTTIAAYWHGTQARRELRRLKEEARNKH 810
Query: 2862 AAITLQHYFRTWQTRKQFLLY-----RKAAVVLQNHYRAFLSAKHQRQVYLQIRSSVIII 2916
A + Y+ + R++ RK AV + Y L + + + + + + I
Sbjct: 811 AIAVIWAYWLGSKARRELKRLKEEARRKHAVAVIWAYWLGLKVRREYRKFFRANAGKKIY 870
Query: 2917 QARSKGFIQKRKFQEIKNSTIKIQAMWRRYRAKKYLCKVKAACKIQAWYRCWRAHK 2972
+ + +QK F E+KN + + + + ++ YL +++ + WR K
Sbjct: 871 EFTLQRIVQKY-FLEMKNKMPSLSPIDKNWPSRPYLFLDSTHKELKRIFHLWRCKK 925
>gi|240120050 myosin IB isoform 1 [Homo sapiens]
Length = 1136
Score = 58.9 bits (141), Expect = 8e-08
Identities = 46/168 (27%), Positives = 78/168 (46%), Gaps = 16/168 (9%)
Query: 1864 LHDTRTHFLKTKAAVISLQSAYRGWKVRKQIRREHQAALKIQSAFRMAKAQKQFRLFKTA 1923
L D R L+ A +I Q YRGWK R ++ + I + +R QK+++ K++
Sbjct: 696 LEDLRKQRLEDLATLI--QKIYRGWKCRTHFLLMKKSQIVIAAWYRRYAQQKRYQQTKSS 753
Query: 1924 ALVIQQNFRAWTAGR--KQCMEYIELRHAVLVLQSMWKGKTLRRQLQR-------QHKCA 1974
ALVIQ R W A + ++ + AV + + W G RR+L+R +H A
Sbjct: 754 ALVIQSYIRGWKARKILRELKHQKRCKEAVTTIAAYWHGTQARRELRRLKEEARNKHAIA 813
Query: 1975 II----IQSYYRMHVQQKKWKIMKK-AALLIQKYYRAYSIGREQNHLY 2017
+I + S R +++ K + +K A +I Y+ + RE +
Sbjct: 814 VIWAYWLGSKARRELKRLKEEARRKHAVAVIWAYWLGLKVRREYRKFF 861
Score = 55.8 bits (133), Expect = 7e-07
Identities = 56/199 (28%), Positives = 89/199 (44%), Gaps = 34/199 (17%)
Query: 2007 YSIGREQNHLYLKTKAAVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYATY 2066
YS GR + ++++ + L+ + +R++D A IQ YR +K + +
Sbjct: 678 YSFGRSK--IFIRNPRTLFKLEDLRK-----QRLEDL---ATLIQKIYRGWKCRTHFLLM 727
Query: 2067 RASAIIIQRWYRGIKITNHQHKEYLNLKKTAIKIQSVYRGIRVR---RHIQHMHR---AA 2120
+ S I+I WYR Q K Y K +A+ IQS RG + R R ++H R A
Sbjct: 728 KKSQIVIAAWYRRYA----QQKRYQQTKSSALVIQSYIRGWKARKILRELKHQKRCKEAV 783
Query: 2121 TFIKAMFKMHQS-----RISYHTMRKAAIVIQVRCRAYYQGKMQREKYLTILK------A 2169
T I A + Q+ R+ K AI + AY+ G R + + + A
Sbjct: 784 TTIAAYWHGTQARRELRRLKEEARNKHAIAV---IWAYWLGSKARRELKRLKEEARRKHA 840
Query: 2170 VKVLQASFRGVRVRRTLRK 2188
V V+ A + G++VRR RK
Sbjct: 841 VAVIWAYWLGLKVRREYRK 859
Score = 55.8 bits (133), Expect = 7e-07
Identities = 78/336 (23%), Positives = 134/336 (39%), Gaps = 109/336 (32%)
Query: 1334 KLLMLKKEKLEKVQNKAASLIQGYWRRYSTRQRFLKLKYYSIILQSRIRMIIAVTSYKRY 1393
KL L+K++LE + A+LIQ +R + R FL +K I++
Sbjct: 695 KLEDLRKQRLEDL----ATLIQKIYRGWKCRTHFLLMKKSQIVIA--------------- 735
Query: 1394 LWATVTIQRHWRAYLRRKQDQQRYEMLKSSTLIIQSMFRKWKQRKM------QSQVKATV 1447
A+ RR Q+RY+ KSS L+IQS R WK RK+ Q + K V
Sbjct: 736 ------------AWYRRYAQQKRYQQTKSSALVIQSYIRGWKARKILRELKHQKRCKEAV 783
Query: 1448 ILQRAFREWH----------LRKQAKEENSAIIIQSWY------RMHKELRKYIYIRSCV 1491
A+ WH L+++A+ +++ +I +++ R K L++ + V
Sbjct: 784 TTIAAY--WHGTQARRELRRLKEEARNKHAIAVIWAYWLGSKARRELKRLKEEARRKHAV 841
Query: 1492 VII-------------QKRFRCFQAQKLYKRRKESILTIQKYYKAYLKGKIERTNYLQKR 1538
+I +K FR +K+Y+ + I +QKY+ +K K+ + + K
Sbjct: 842 AVIWAYWLGLKVRREYRKFFRANAGKKIYEFTLQRI--VQKYF-LEMKNKMPSLSPIDKN 898
Query: 1539 AAA---IQLQAAFRRLKAHNLCRQIRAACVIQSYWRMRQDRVRFLNLKKTIIK------- 1588
+ + L + + LK I WR ++ R +F + +K I +
Sbjct: 899 WPSRPYLFLDSTHKELKR------------IFHLWRCKKYRDQFTDQQKLIYEEKLEASE 946
Query: 1589 ----------------FQAHVRKHQQRQKYKKMKKA 1608
FQ + + KYKK+K A
Sbjct: 947 LFKDKKALYPSSVGQPFQGAYLEINKNPKYKKLKDA 982
Score = 52.0 bits (123), Expect = 1e-05
Identities = 58/252 (23%), Positives = 98/252 (38%), Gaps = 47/252 (18%)
Query: 2093 LKKTAIKIQSVYRGIRVRRHIQHMHRAATFIKAMFKMHQSRISYHTMRKAAIVIQVRCRA 2152
L+ A IQ +YRG + R H M ++ I A ++ + + Y + +A+VIQ R
Sbjct: 704 LEDLATLIQKIYRGWKCRTHFLLMKKSQIVIAAWYRRYAQQKRYQQTKSSALVIQSYIRG 763
Query: 2153 YYQGKMQRE-KYLTILK-AVKVLQASFRGVRVRRTLRKMQTAATLIQSNYRRYRQQTYFN 2210
+ K+ RE K+ K AV + A + G + RR LR+++ A
Sbjct: 764 WKARKILRELKHQKRCKEAVTTIAAYWHGTQARRELRRLKEEAR---------------- 807
Query: 2211 KLKKITKTVQQRYWAMKERNIQFQRYN---KLRHSVIYIQAIFRGKKARRHLKMMHIA-- 2265
K V YW + + +R + +H+V I A + G K RR + A
Sbjct: 808 --NKHAIAVIWAYWLGSKARRELKRLKEEARRKHAVAVIWAYWLGLKVRREYRKFFRANA 865
Query: 2266 ---------ATLIQRRFRTLMMR-------------RRFLSLKKTAILIQRKYRAHLCTK 2303
++Q+ F + + R +L L T ++R + C K
Sbjct: 866 GKKIYEFTLQRIVQKYFLEMKNKMPSLSPIDKNWPSRPYLFLDSTHKELKRIFHLWRCKK 925
Query: 2304 HHLQFLQVQNAV 2315
+ QF Q +
Sbjct: 926 YRDQFTDQQKLI 937
Score = 51.2 bits (121), Expect = 2e-05
Identities = 29/95 (30%), Positives = 55/95 (57%), Gaps = 2/95 (2%)
Query: 2672 IQSYYRGFKVRKDIQNMHRAATLIQSFYRMHRAKVDYETKKTAIVVIQNYYRLYV--RVK 2729
IQ YRG+K R M ++ +I ++YR + + Y+ K++ +VIQ+Y R + ++
Sbjct: 711 IQKIYRGWKCRTHFLLMKKSQIVIAAWYRRYAQQKRYQQTKSSALVIQSYIRGWKARKIL 770
Query: 2730 TERKNFLAVQKSVRTIQAAFRGMKVRQKLKNVSEE 2764
E K+ +++V TI A + G + R++L+ + EE
Sbjct: 771 RELKHQKRCKEAVTTIAAYWHGTQARRELRRLKEE 805
Score = 50.8 bits (120), Expect = 2e-05
Identities = 59/254 (23%), Positives = 112/254 (44%), Gaps = 24/254 (9%)
Query: 2451 LYQFLHLRKAAITIQSSYRRLMVKKKLQEMQR-------AAVLIQATFRMYRTYITFQTW 2503
L + + +R+A + +Y + + K+ Q A ++ F + ++
Sbjct: 621 LLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPARSGVEVLFNELEIPVEEYSF 680
Query: 2504 KHASILIQQHYRTYRAAKLQRENYIRQWHSAVVIQAAYKGMKARQLLREKHKASIVIQST 2563
+ I I+ ++ L+++ R A +IQ Y+G K R K+ IVI +
Sbjct: 681 GRSKIFIRNPRTLFKLEDLRKQ---RLEDLATLIQKIYRGWKCRTHFLLMKKSQIVIAAW 737
Query: 2564 YRMYRQYCFYQKLQWATKIIQEKYRANKKKQ--KVFQHNELKKE--TCVQAGFQDMNIKK 2619
YR Y Q YQ+ + + +IQ R K ++ + +H + KE T + A + ++
Sbjct: 738 YRRYAQQKRYQQTKSSALVIQSYIRGWKARKILRELKHQKRCKEAVTTIAAYWHGTQARR 797
Query: 2620 QIQEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQRRYRKL--TAVRTQAVICIQSYYR 2677
+++ + A KH A I ++L +A +R ++L A R AV I +Y+
Sbjct: 798 ELRRLKEEA--RNKHAIAV-IWAYWLGSKA-----RRELKRLKEEARRKHAVAVIWAYWL 849
Query: 2678 GFKVRKDIQNMHRA 2691
G KVR++ + RA
Sbjct: 850 GLKVRREYRKFFRA 863
Score = 49.3 bits (116), Expect = 7e-05
Identities = 54/224 (24%), Positives = 90/224 (40%), Gaps = 55/224 (24%)
Query: 2235 RYNKLRHSVIYIQAIFRGKKARRHLKMMHIAATLIQRRFRTLMMRRRFLSLKKTAILIQR 2294
R +L IQ I+RG K R H FL +KK+ I+I
Sbjct: 700 RKQRLEDLATLIQKIYRGWKCRTH-----------------------FLLMKKSQIVIAA 736
Query: 2295 KYRAHLCTKHHLQFLQVQNAVIKIQSSYRRWMIRKRMREMHRAATFIQSTFRMHRLHMRY 2354
YR + K ++ Q +++ + IQS R W RK +RE+
Sbjct: 737 WYRRYAQQK---RYQQTKSSALVIQSYIRGWKARKILREL-----------------KHQ 776
Query: 2355 QALKQASVVIQQQYQANRAAKLQR--QHYLRQRHSAVILQAAFRGMKTRRHLKSMHSSAT 2412
+ K+A I + +A + R + R +H+ ++ A + G K RR LK + A
Sbjct: 777 KRCKEAVTTIAAYWHGTQARRELRRLKEEARNKHAIAVIWAYWLGSKARRELKRLKEEA- 835
Query: 2413 LIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAK--HKLYQF 2454
+ + ++ ++ LK V+R+YR A K+Y+F
Sbjct: 836 --RRKHAVAVIWAYWLGLK-----VRREYRKFFRANAGKKIYEF 872
Score = 48.9 bits (115), Expect = 9e-05
Identities = 28/100 (28%), Positives = 55/100 (55%), Gaps = 10/100 (10%)
Query: 2863 AITLQHYFRTWQTRKQFLLYRKAAVVLQNHYRAFLSAKHQRQVYLQIRSSVIIIQARSKG 2922
A +Q +R W+ R FLL +K+ +V+ YR + Q++ Y Q +SS ++IQ+ +G
Sbjct: 708 ATLIQKIYRGWKCRTHFLLMKKSQIVIAAWYRRYA----QQKRYQQTKSSALVIQSYIRG 763
Query: 2923 FIQKRKFQEIKN------STIKIQAMWRRYRAKKYLCKVK 2956
+ ++ +E+K+ + I A W +A++ L ++K
Sbjct: 764 WKARKILRELKHQKRCKEAVTTIAAYWHGTQARRELRRLK 803
Score = 48.1 bits (113), Expect = 1e-04
Identities = 62/292 (21%), Positives = 118/292 (40%), Gaps = 67/292 (22%)
Query: 1630 QKTRSAVIVLQSAYRGMQARKMYIHILTSVIKIQSYYRAYVSKKEFLSLKNATIKLQSTV 1689
Q+ ++Q YRG + R ++ + S I I ++YR Y +K + K++ + +QS +
Sbjct: 702 QRLEDLATLIQKIYRGWKCRTHFLLMKKSQIVIAAWYRRYAQQKRYQQTKSSALVIQSYI 761
Query: 1690 KMKQTRKQYLHLRAAALFIQQCYRSKKIAAQKREEYMQMRESCIKLQAFVRGYLVRKQMR 1749
+ + RK +++ QKR +E+ + A+ G R+++R
Sbjct: 762 RGWKARKIL----------------RELKHQKR-----CKEAVTTIAAYWHGTQARRELR 800
Query: 1750 LQRKAVISLQSYFRMRKARQYYLKMYKAIIVIQNYYHAYKA--QVNQRKNFLQVKKAATC 1807
++ +AR + AI VI Y+ KA ++ + K + K A
Sbjct: 801 RLKE------------EARNKH-----AIAVIWAYWLGSKARRELKRLKEEARRKHAVAV 843
Query: 1808 LQAAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRVKYQSVLQSIIKIQRWYRAYKTLHDT 1867
+ A + G KVR+ + + FR + Y+ LQ I+
Sbjct: 844 IWAYWLGLKVRR----------EYRKFFRANAGKKIYEFTLQRIV--------------- 878
Query: 1868 RTHFLKTKAAVISLQSAYRGWKVRKQIRRE--HQAALKIQSAFRMAKAQKQF 1917
+ +FL+ K + SL + W R + + H+ +I +R K + QF
Sbjct: 879 QKYFLEMKNKMPSLSPIDKNWPSRPYLFLDSTHKELKRIFHLWRCKKYRDQF 930
Score = 47.4 bits (111), Expect = 3e-04
Identities = 26/90 (28%), Positives = 53/90 (58%), Gaps = 2/90 (2%)
Query: 1563 ACVIQSYWRMRQDRVRFLNLKKTIIKFQAHVRKHQQRQKYKKMKKAAVIIQTHFRAYIF- 1621
A +IQ +R + R FL +KK+ I A R++ Q+++Y++ K +A++IQ++ R +
Sbjct: 708 ATLIQKIYRGWKCRTHFLLMKKSQIVIAAWYRRYAQQKRYQQTKSSALVIQSYIRGWKAR 767
Query: 1622 -AMKVLASYQKTRSAVIVLQSAYRGMQARK 1650
++ L ++ + AV + + + G QAR+
Sbjct: 768 KILRELKHQKRCKEAVTTIAAYWHGTQARR 797
Score = 47.0 bits (110), Expect = 3e-04
Identities = 46/166 (27%), Positives = 74/166 (44%), Gaps = 19/166 (11%)
Query: 2187 RKMQTAATLIQSNYRRYRQQTYFNKLKKITKTVQQRYWAMKERNIQFQRYNKLRHSVIYI 2246
++++ ATLIQ YR ++ +T+F +KK + Y R Q +RY + + S + I
Sbjct: 702 QRLEDLATLIQKIYRGWKCRTHFLLMKKSQIVIAAWY----RRYAQQKRYQQTKSSALVI 757
Query: 2247 QAIFRGKKAR------RHLKMMHIAATLIQRRFRTLMMRRRFLSLK-----KTAILIQRK 2295
Q+ RG KAR +H K A T I + RR LK K AI +
Sbjct: 758 QSYIRGWKARKILRELKHQKRCKEAVTTIAAYWHGTQARRELRRLKEEARNKHAIAVIWA 817
Query: 2296 YRAHLCTKHHLQFLQVQ----NAVIKIQSSYRRWMIRKRMREMHRA 2337
Y + L+ L+ + +AV I + + +R+ R+ RA
Sbjct: 818 YWLGSKARRELKRLKEEARRKHAVAVIWAYWLGLKVRREYRKFFRA 863
Score = 46.2 bits (108), Expect = 6e-04
Identities = 64/248 (25%), Positives = 112/248 (45%), Gaps = 35/248 (14%)
Query: 1259 RLLDLRKEIRA--ARLIQTTWRKYKLKTDLKRHQEREKAARIIQLAVINFLAKQ-RLRKR 1315
+L DLRK+ A LIQ +R +K +T H K ++I+ A A+Q R ++
Sbjct: 695 KLEDLRKQRLEDLATLIQKIYRGWKCRT----HFLLMKKSQIVIAAWYRRYAQQKRYQQT 750
Query: 1316 VNAALVIQKYWRRVLAQRKLLMLKKEKLEKVQNKAASLIQGYWRRYSTRQRFLKLKYYSI 1375
++ALVIQ Y R A++ L LK +K K +A + I YW R+ +LK
Sbjct: 751 KSSALVIQSYIRGWKARKILRELKHQKRCK---EAVTTIAAYWHGTQARRELRRLKE--- 804
Query: 1376 ILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQRYEMLKS-----STLIIQSM 1430
++R + IAV +WA + R R K++ +R + L ++
Sbjct: 805 --EARNKHAIAV------IWAYWLGSKARRELKRLKEEARRKHAVAVIWAYWLGLKVRRE 856
Query: 1431 FRKWKQRKMQSQVKATVILQRAFREWHLRKQAKEENSAIIIQSW--------YRMHKELR 1482
+RK+ + ++ LQR +++ L + K + + I ++W HKEL+
Sbjct: 857 YRKFFRANAGKKI-YEFTLQRIVQKYFLEMKNKMPSLSPIDKNWPSRPYLFLDSTHKELK 915
Query: 1483 KYIYIRSC 1490
+ ++ C
Sbjct: 916 RIFHLWRC 923
Score = 45.4 bits (106), Expect = 0.001
Identities = 58/236 (24%), Positives = 106/236 (44%), Gaps = 42/236 (17%)
Query: 2870 FRTWQTRKQFLLYRKAAVVLQNHYRAFLSAKHQRQVYLQIRSSVIIIQARSKGFIQKRKF 2929
F+ RKQ L A ++Q YR + H +L ++ S I+I A + + Q++++
Sbjct: 694 FKLEDLRKQRL--EDLATLIQKIYRGWKCRTH----FLLMKKSQIVIAAWYRRYAQQKRY 747
Query: 2930 QEIKNSTIKIQAMWRRYRAKKYLCKVK-------AACKIQAWYRCWRAHKEYLAILKAVK 2982
Q+ K+S + IQ+ R ++A+K L ++K A I A++ +A +E L+ +K
Sbjct: 748 QQTKSSALVIQSYIRGWKARKILRELKHQKRCKEAVTTIAAYWHGTQARRE----LRRLK 803
Query: 2983 IIQGCFYTKLERTRFLNVRASAIIIQRKWRAILPAKIAHEHFLM---IKRHRAACLIQAH 3039
E R N A A+I W L +K E + +R A +I A+
Sbjct: 804 ----------EEAR--NKHAIAVI----WAYWLGSKARRELKRLKEEARRKHAVAVIWAY 847
Query: 3040 YRGYKGRQVFLR--QKSAALIIQKYIRAREAGKHERIKYIEFKKSTVILQALVRGW 3093
+ G K R+ + + + +A I ++ R K+ ++E K L + + W
Sbjct: 848 WLGLKVRREYRKFFRANAGKKIYEFTLQRIVQKY----FLEMKNKMPSLSPIDKNW 899
Score = 43.1 bits (100), Expect = 0.005
Identities = 42/187 (22%), Positives = 81/187 (43%), Gaps = 21/187 (11%)
Query: 2375 KLQRQHYLRQRHSAVILQAAFRGMKTRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKAT 2434
KL+ R A ++Q +RG K R H M S +I + +R ++R+ K +
Sbjct: 695 KLEDLRKQRLEDLATLIQKIYRGWKCRTHFLLMKKSQIVIAAWYRRYAQQKRYQQTKSSA 754
Query: 2435 IFVQRKYRATICAK--HKLYQFLHLRKAAITIQSSYRRLMVKKKLQEMQRAAVLIQATFR 2492
+ +Q R K +L ++A TI + + +++L+ ++ A
Sbjct: 755 LVIQSYIRGWKARKILRELKHQKRCKEAVTTIAAYWHGTQARRELRRLKEEA-------- 806
Query: 2493 MYRTYITFQTWKHASILIQQHYRTYRAAK-LQR-ENYIRQWHSAVVIQAAYKGMKARQLL 2550
KHA +I ++ +A + L+R + R+ H+ VI A + G+K R+
Sbjct: 807 ---------RNKHAIAVIWAYWLGSKARRELKRLKEEARRKHAVAVIWAYWLGLKVRREY 857
Query: 2551 REKHKAS 2557
R+ +A+
Sbjct: 858 RKFFRAN 864
Score = 43.1 bits (100), Expect = 0.005
Identities = 43/210 (20%), Positives = 83/210 (39%), Gaps = 18/210 (8%)
Query: 2686 QNMHRAATLIQSFYRMHRAKVDYETKKTAIVVIQNYYRLYVRVKTERKNFLAVQKSVRTI 2745
Q + ATLIQ YR + + + K + +VI +YR Y ++K + + S I
Sbjct: 702 QRLEDLATLIQKIYRGWKCRTHFLLMKKSQIVIAAWYRRY----AQQKRYQQTKSSALVI 757
Query: 2746 QAAFRGMKVRQKLKNVSEEKMAAIV----------NQSALCCYRSKTQYEAVQSEGVMIQ 2795
Q+ RG K R+ L+ + +K Q+ R K + + V+
Sbjct: 758 QSYIRGWKARKILRELKHQKRCKEAVTTIAAYWHGTQARRELRRLKEEARNKHAIAVIWA 817
Query: 2796 EWYKASGLACSQEAEYHSQSRAAVTIQKAFCRMVTRKLETQKC----AALRIQFFLQMAV 2851
W + + + ++ + AV + A+ + + E +K A +I F +
Sbjct: 818 YWLGSKARRELKRLKEEARRKHAVAVIWAYWLGLKVRREYRKFFRANAGKKIYEFTLQRI 877
Query: 2852 YRRRFVQQKRAAITLQHYFRTWQTRKQFLL 2881
++ F++ K +L + W +R L
Sbjct: 878 VQKYFLEMKNKMPSLSPIDKNWPSRPYLFL 907
Score = 42.7 bits (99), Expect = 0.006
Identities = 42/155 (27%), Positives = 70/155 (45%), Gaps = 34/155 (21%)
Query: 2622 QEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQRRYRKLTAVRTQAVICIQSYYRGFKV 2681
Q A +IQK + +K R H+L ++ ++ I I ++YR +
Sbjct: 702 QRLEDLATLIQKIYRGWKCRTHFLLMK------------------KSQIVIAAWYRRYAQ 743
Query: 2682 RKDIQNMHRAATLIQSFYRMHRA-KVDYETK-----KTAIVVIQNYY------RLYVRVK 2729
+K Q +A +IQS+ R +A K+ E K K A+ I Y+ R R+K
Sbjct: 744 QKRYQQTKSSALVIQSYIRGWKARKILRELKHQKRCKEAVTTIAAYWHGTQARRELRRLK 803
Query: 2730 TERKNFLAVQKSVRTIQAAFRGMKVRQKLKNVSEE 2764
E +N + ++ I A + G K R++LK + EE
Sbjct: 804 EEARN----KHAIAVIWAYWLGSKARRELKRLKEE 834
Score = 40.8 bits (94), Expect = 0.024
Identities = 41/179 (22%), Positives = 72/179 (40%), Gaps = 26/179 (14%)
Query: 1277 WRKYKLKTDLKRHQEREKAARIIQLAVINFLAKQRLRK------RVNAALVIQKYWRRVL 1330
W+ K+ +LK + ++A I A++ LR+ +A VI YW
Sbjct: 764 WKARKILRELKHQKRCKEAVTTIAAYWHGTQARRELRRLKEEARNKHAIAVIWAYWLGSK 823
Query: 1331 AQRKLLMLKKEKLEKVQNKAASLIQGYWRRYSTRQRFLKL-------KYYSIILQSRIRM 1383
A+R+L LK+E K A ++I YW R+ + K K Y LQ ++
Sbjct: 824 ARRELKRLKEEARRK---HAVAVIWAYWLGLKVRREYRKFFRANAGKKIYEFTLQRIVQK 880
Query: 1384 IIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQRYEMLKSSTLIIQSMFRKWKQRKMQSQ 1442
K + + I ++W + Y L S+ ++ +F W+ +K + Q
Sbjct: 881 YF--LEMKNKMPSLSPIDKNW--------PSRPYLFLDSTHKELKRIFHLWRCKKYRDQ 929
Score = 40.4 bits (93), Expect = 0.031
Identities = 43/185 (23%), Positives = 83/185 (44%), Gaps = 29/185 (15%)
Query: 1599 RQKYKKMKKAAVIIQTHFRAYIFAMKVLASYQKTRSAVIVLQSAYRGMQARKMYIHI--- 1655
R + MKK+ ++I +R Y + YQ+T+S+ +V+QS RG +ARK+ +
Sbjct: 721 RTHFLLMKKSQIVIAAWYRRYAQQKR----YQQTKSSALVIQSYIRGWKARKILRELKHQ 776
Query: 1656 ---LTSVIKIQSYYRAYVSKKEFLSLKNATIKLQSTVKMKQTRKQYLHLRAAALFIQQCY 1712
+V I +Y+ +++E LK ++ R ++ A A+
Sbjct: 777 KRCKEAVTTIAAYWHGTQARRELRRLK------------EEARNKH----AIAVIWAYWL 820
Query: 1713 RSKKIAAQKR-EEYMQMRESCIKLQAFVRGYLVRKQMR--LQRKAVISLQSYFRMRKARQ 1769
SK KR +E + + + + A+ G VR++ R + A + + R ++
Sbjct: 821 GSKARRELKRLKEEARRKHAVAVIWAYWLGLKVRREYRKFFRANAGKKIYEFTLQRIVQK 880
Query: 1770 YYLKM 1774
Y+L+M
Sbjct: 881 YFLEM 885
Score = 33.1 bits (74), Expect = 4.9
Identities = 45/236 (19%), Positives = 97/236 (41%), Gaps = 25/236 (10%)
Query: 2757 KLKNVSEEKMA--AIVNQSALCCYRSKTQYEAVQSEGVMIQEWYKASGLACSQEAEYHSQ 2814
KL+++ ++++ A + Q ++ +T + ++ ++I WY+ +Q+ Y
Sbjct: 695 KLEDLRKQRLEDLATLIQKIYRGWKCRTHFLLMKKSQIVIAAWYRRY----AQQKRYQQT 750
Query: 2815 SRAAVTIQKAF----CRMVTRKLETQK-C--AALRIQFFLQMAVYRRRF------VQQKR 2861
+A+ IQ R + R+L+ QK C A I + RR + K
Sbjct: 751 KSSALVIQSYIRGWKARKILRELKHQKRCKEAVTTIAAYWHGTQARRELRRLKEEARNKH 810
Query: 2862 AAITLQHYFRTWQTRKQFLLY-----RKAAVVLQNHYRAFLSAKHQRQVYLQIRSSVIII 2916
A + Y+ + R++ RK AV + Y L + + + + + + I
Sbjct: 811 AIAVIWAYWLGSKARRELKRLKEEARRKHAVAVIWAYWLGLKVRREYRKFFRANAGKKIY 870
Query: 2917 QARSKGFIQKRKFQEIKNSTIKIQAMWRRYRAKKYLCKVKAACKIQAWYRCWRAHK 2972
+ + +QK F E+KN + + + + ++ YL +++ + WR K
Sbjct: 871 EFTLQRIVQKY-FLEMKNKMPSLSPIDKNWPSRPYLFLDSTHKELKRIFHLWRCKK 925
>gi|29826341 calmodulin binding transcription activator 2 [Homo
sapiens]
Length = 1202
Score = 57.4 bits (137), Expect = 2e-07
Identities = 51/176 (28%), Positives = 79/176 (44%), Gaps = 34/176 (19%)
Query: 2159 QREKYLTILKAVKVLQASFRGVRVRRTLRKMQTAATLIQSNYRRYRQQTYFNKLKKITKT 2218
QRE Y +A +V+Q +FR + RR + + AA +IQ YR+Y+Q T+
Sbjct: 1045 QRELY----EAARVIQTAFRKYKGRRLKEQQEVAAAVIQRCYRKYKQLTWI--------- 1091
Query: 2219 VQQRYWAMKERNIQFQRYNKLRHSVIYIQAIFRGKKARRHLKMMHIAATLIQRRFRTLMM 2278
++F Y K+ + I IQ+ FR ++ + AA LIQ+ +R+
Sbjct: 1092 -----------ALKFALYKKMTQAAILIQSKFRSYYEQKRFQQSRRAAVLIQQHYRS--Y 1138
Query: 2279 RRRFLSLKKTAILIQRKYRAHLCTKHHLQFLQVQNAVIKIQSSYRRWMIRKRMREM 2334
RRR +T+ + + + TK Q A KI RR R RMRE+
Sbjct: 1139 RRRPGPPHRTSATLPARNKGSFLTKKQDQ------AARKIMRFLRR--CRHRMREL 1186
Score = 53.9 bits (128), Expect = 3e-06
Identities = 42/162 (25%), Positives = 74/162 (45%), Gaps = 36/162 (22%)
Query: 2523 QRENYIRQWHSAVVIQAAYKGMKARQLLREKHKASIVIQSTYRMYRQ-------YCFYQK 2575
QRE Y +A VIQ A++ K R+L ++ A+ VIQ YR Y+Q + Y+K
Sbjct: 1045 QRELY----EAARVIQTAFRKYKGRRLKEQQEVAAAVIQRCYRKYKQLTWIALKFALYKK 1100
Query: 2576 LQWATKIIQEKYRANKKKQKVFQHNELKKETCVQAGFQDMNIKKQIQEQHQAAIIIQKHC 2635
+ A +IQ K+R+ + +K+ Q+ +AA++IQ+H
Sbjct: 1101 MTQAAILIQSKFRSYYE-------------------------QKRFQQSRRAAVLIQQHY 1135
Query: 2636 KAFKIRKHYLHLRATVVSIQRRYRKLTAVRTQAVICIQSYYR 2677
++++ R H + + + + LT + QA I + R
Sbjct: 1136 RSYRRRPGPPHRTSATLPARNKGSFLTKKQDQAARKIMRFLR 1177
Score = 53.9 bits (128), Expect = 3e-06
Identities = 37/114 (32%), Positives = 58/114 (50%), Gaps = 20/114 (17%)
Query: 2405 KSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKHKLYQFLHLRKAAITI 2464
+ ++ +A +IQ+ FR RR + A +QR YR K+K ++ L+ A
Sbjct: 1046 RELYEAARVIQTAFRKYKGRRLKEQQEVAAAVIQRCYR-----KYKQLTWIALKFALY-- 1098
Query: 2465 QSSYRRLMVKKKLQEMQRAAVLIQATFRMYRTYITFQTWKHASILIQQHYRTYR 2518
++M +AA+LIQ+ FR Y FQ + A++LIQQHYR+YR
Sbjct: 1099 -------------KKMTQAAILIQSKFRSYYEQKRFQQSRRAAVLIQQHYRSYR 1139
Score = 52.8 bits (125), Expect = 6e-06
Identities = 42/154 (27%), Positives = 79/154 (51%), Gaps = 25/154 (16%)
Query: 1895 RREHQAALKIQSAFRMAKAQKQFRLFKTAALVIQQNFRAWTAGRKQCMEYIELRHAVLVL 1954
R ++AA IQ+AFR K ++ + AA VIQ+ +R + KQ + +I L+ A+
Sbjct: 1046 RELYEAARVIQTAFRKYKGRRLKEQQEVAAAVIQRCYRKY----KQ-LTWIALKFALY-- 1098
Query: 1955 QSMWKGKTLRRQLQRQHKCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYRAYSIGREQN 2014
++ + AI+IQS +R + +QK+++ ++AA+LIQ++YR+Y
Sbjct: 1099 -------------KKMTQAAILIQSKFRSYYEQKRFQQSRRAAVLIQQHYRSYRRRPGPP 1145
Query: 2015 H-----LYLKTKAAVVTLQSAYRGMKVRKRIKDC 2043
H L + K + +T + K+ + ++ C
Sbjct: 1146 HRTSATLPARNKGSFLTKKQDQAARKIMRFLRRC 1179
Score = 50.4 bits (119), Expect = 3e-05
Identities = 41/158 (25%), Positives = 70/158 (44%), Gaps = 14/158 (8%)
Query: 2622 QEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQRRYRK------------LTAVRTQAV 2669
+E ++AA +IQ + +K R+ IQR YRK L TQA
Sbjct: 1046 RELYEAARVIQTAFRKYKGRRLKEQQEVAAAVIQRCYRKYKQLTWIALKFALYKKMTQAA 1105
Query: 2670 ICIQSYYRGFKVRKDIQNMHRAATLIQSFYRMHRAKVDYETKKTAIVVIQNYYRLYVRVK 2729
I IQS +R + +K Q RAA LIQ YR +R + + +A + +N + +
Sbjct: 1106 ILIQSKFRSYYEQKRFQQSRRAAVLIQQHYRSYRRRPGPPHRTSATLPARNKGSFLTKKQ 1165
Query: 2730 TERKNFLAVQKSVRTIQAAFRGMKVRQKLKNVSEEKMA 2767
+ + + +R + R +K Q+L+ + + +A
Sbjct: 1166 DQAAR--KIMRFLRRCRHRMRELKQNQELEGLPQPGLA 1201
Score = 49.3 bits (116), Expect = 7e-05
Identities = 31/99 (31%), Positives = 53/99 (53%), Gaps = 11/99 (11%)
Query: 1800 QVKKAATCLQAAYRGYKVRQLIKQQSIAALKIQSAFRGYN-------KRVKYQSVLQSII 1852
++ +AA +Q A+R YK R+L +QQ +AA IQ +R Y K Y+ + Q+ I
Sbjct: 1047 ELYEAARVIQTAFRKYKGRRLKEQQEVAAAVIQRCYRKYKQLTWIALKFALYKKMTQAAI 1106
Query: 1853 KIQRWYRAYKTLHDTRTHFLKTKAAVISLQSAYRGWKVR 1891
IQ +R+Y + F +++ A + +Q YR ++ R
Sbjct: 1107 LIQSKFRSYY----EQKRFQQSRRAAVLIQQHYRSYRRR 1141
Score = 48.9 bits (115), Expect = 9e-05
Identities = 39/133 (29%), Positives = 61/133 (45%), Gaps = 21/133 (15%)
Query: 1943 EYIELRHAVLVLQSMWKGKTLRRQLQRQHKCAIIIQSYYRMHVQQKKWKIMKKAALLIQK 2002
E EL A V+Q+ ++ RR ++Q A +IQ YR + +Q W +K A
Sbjct: 1044 EQRELYEAARVIQTAFRKYKGRRLKEQQEVAAAVIQRCYRKY-KQLTWIALKFA------ 1096
Query: 2003 YYRAYSIGREQNHLYLKTKAAVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKK 2062
LY K A + +QS +R +KR + +AAV IQ YR+Y+ ++
Sbjct: 1097 -------------LYKKMTQAAILIQSKFRSYYEQKRFQQSRRAAVLIQQHYRSYR-RRP 1142
Query: 2063 YATYRASAIIIQR 2075
+R SA + R
Sbjct: 1143 GPPHRTSATLPAR 1155
Score = 48.1 bits (113), Expect = 1e-04
Identities = 33/137 (24%), Positives = 73/137 (53%), Gaps = 17/137 (12%)
Query: 1389 SYKRYLWATVTIQRHWRAYLRRKQDQQRYEMLKSSTLIIQSMFRKWKQRKMQSQVK-ATV 1447
S+ +L A+ + + L D ++ E+ +++ +IQ+ FRK+K R+++ Q + A
Sbjct: 1018 SWAEFLSASTSGKMESDFALLTLSDHEQRELYEAAR-VIQTAFRKYKGRRLKEQQEVAAA 1076
Query: 1448 ILQRAFREWHLRKQAKEENSAIIIQSWYRMHKELRKYIYIRSCVVIIQKRFRCFQAQKLY 1507
++QR +R++ KQ +W + L Y + ++IQ +FR + QK +
Sbjct: 1077 VIQRCYRKY---KQL----------TWIALKFAL--YKKMTQAAILIQSKFRSYYEQKRF 1121
Query: 1508 KRRKESILTIQKYYKAY 1524
++ + + + IQ++Y++Y
Sbjct: 1122 QQSRRAAVLIQQHYRSY 1138
Score = 48.1 bits (113), Expect = 1e-04
Identities = 39/143 (27%), Positives = 75/143 (52%), Gaps = 15/143 (10%)
Query: 1286 LKRHQERE--KAARIIQLAVINFLAKQRLRKRVNAALVIQKYWRRVLAQRKLLMLKKEKL 1343
L H++RE +AAR+IQ A + ++ ++ AA VIQ+ +R+ ++ + K L
Sbjct: 1040 LSDHEQRELYEAARVIQTAFRKYKGRRLKEQQEVAAAVIQRCYRKY--KQLTWIALKFAL 1097
Query: 1344 EKVQNKAASLIQGYWRRYSTRQRFLKLKYYSIILQSRIRMIIAVTSYKR-----YLWATV 1398
K +AA LIQ +R Y ++RF + + ++++Q R SY+R + +
Sbjct: 1098 YKKMTQAAILIQSKFRSYYEQKRFQQSRRAAVLIQQHYR------SYRRRPGPPHRTSAT 1151
Query: 1399 TIQRHWRAYLRRKQDQQRYEMLK 1421
R+ ++L +KQDQ ++++
Sbjct: 1152 LPARNKGSFLTKKQDQAARKIMR 1174
Score = 47.8 bits (112), Expect = 2e-04
Identities = 48/144 (33%), Positives = 75/144 (52%), Gaps = 27/144 (18%)
Query: 2817 AAVTIQKAFCRMVTRKL-ETQKCAALRIQ-----------FFLQMAVYRRRFVQQKRAAI 2864
AA IQ AF + R+L E Q+ AA IQ L+ A+Y++ +AAI
Sbjct: 1051 AARVIQTAFRKYKGRRLKEQQEVAAAVIQRCYRKYKQLTWIALKFALYKK----MTQAAI 1106
Query: 2865 TLQHYFRTWQTRKQFLLYRKAAVVLQNHYRAFLSAKHQRQVYLQIRSSVIIIQARSKG-F 2923
+Q FR++ +K+F R+AAV++Q HYR++ +R+ R+S + AR+KG F
Sbjct: 1107 LIQSKFRSYYEQKRFQQSRRAAVLIQQHYRSY-----RRRPGPPHRTSA-TLPARNKGSF 1160
Query: 2924 IQKRKFQEIKNSTIKIQAMWRRYR 2947
+ K++ Q + KI RR R
Sbjct: 1161 LTKKQDQAAR----KIMRFLRRCR 1180
Score = 45.8 bits (107), Expect = 7e-04
Identities = 36/138 (26%), Positives = 66/138 (47%), Gaps = 6/138 (4%)
Query: 1590 QAHVRKHQQRQKYKKMKKAAVIIQTHFRAYI----FAMKVLASYQKTRSAVIVLQSAYRG 1645
Q RK++ R+ ++ + AA +IQ +R Y A+K A Y+K A I++QS +R
Sbjct: 1056 QTAFRKYKGRRLKEQQEVAAAVIQRCYRKYKQLTWIALK-FALYKKMTQAAILIQSKFRS 1114
Query: 1646 MQARKMYIHILTSVIKIQSYYRAYVSKKEFLSLKNATIKLQSTVKMKQTRKQYLHLRAAA 1705
+K + + + IQ +YR+Y + +AT+ ++ T+KQ R
Sbjct: 1115 YYEQKRFQQSRRAAVLIQQHYRSYRRRPGPPHRTSATLPARNKGSF-LTKKQDQAARKIM 1173
Query: 1706 LFIQQCYRSKKIAAQKRE 1723
F+++C + Q +E
Sbjct: 1174 RFLRRCRHRMRELKQNQE 1191
Score = 44.7 bits (104), Expect = 0.002
Identities = 33/121 (27%), Positives = 62/121 (51%), Gaps = 21/121 (17%)
Query: 1962 TLRRQLQRQ-HKCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYRAYSIGREQNHLYLKT 2020
TL QR+ ++ A +IQ+ +R + ++ + + AA +IQ+ YR Y + ++
Sbjct: 1039 TLSDHEQRELYEAARVIQTAFRKYKGRRLKEQQEVAAAVIQRCYRKY-----KQLTWIAL 1093
Query: 2021 KAAVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGI 2080
K A+ K +AA+ IQSK+R+Y +K++ R +A++IQ+ YR
Sbjct: 1094 KFALY---------------KKMTQAAILIQSKFRSYYEQKRFQQSRRAAVLIQQHYRSY 1138
Query: 2081 K 2081
+
Sbjct: 1139 R 1139
Score = 44.7 bits (104), Expect = 0.002
Identities = 36/154 (23%), Positives = 78/154 (50%), Gaps = 15/154 (9%)
Query: 2457 LRKAAITIQSSYRRLMVKKKLQEMQRAAVLIQATFRMYRT-------YITFQTWKHASIL 2509
L +AA IQ+++R+ ++ ++ + AA +IQ +R Y+ + ++ A+IL
Sbjct: 1048 LYEAARVIQTAFRKYKGRRLKEQQEVAAAVIQRCYRKYKQLTWIALKFALYKKMTQAAIL 1107
Query: 2510 IQQHYRTYRAAKLQRENYIRQWHSAVVIQAAYKGMKARQLLREKHKASIVIQSTYRMYRQ 2569
IQ +R+Y +++ + + +AV+IQ Y+ + R H+ S + + R
Sbjct: 1108 IQSKFRSY----YEQKRFQQSRRAAVLIQQHYRSYRRRP--GPPHRTSATLPA--RNKGS 1159
Query: 2570 YCFYQKLQWATKIIQEKYRANKKKQKVFQHNELK 2603
+ ++ Q A KI++ R + +++ Q+ EL+
Sbjct: 1160 FLTKKQDQAARKIMRFLRRCRHRMRELKQNQELE 1193
Score = 43.9 bits (102), Expect = 0.003
Identities = 35/147 (23%), Positives = 68/147 (46%), Gaps = 9/147 (6%)
Query: 3030 HRAACLIQAHYRGYKGRQVFLRQKSAALIIQKYIRAREAGKHERIKYIEFKKST---VIL 3086
+ AA +IQ +R YKGR++ +Q+ AA +IQ+ R + +K+ +KK T +++
Sbjct: 1049 YEAARVIQTAFRKYKGRRLKEQQEVAAAVIQRCYRKYKQLTWIALKFALYKKMTQAAILI 1108
Query: 3087 QALVRGWLVRKRFLEQRAKIRLLHFTAAAYY------HLNAVRIQRAYKLYLAVKNANKQ 3140
Q+ R + +KRF + R L+ +Y H + + K K ++
Sbjct: 1109 QSKFRSYYEQKRFQQSRRAAVLIQQHYRSYRRRPGPPHRTSATLPARNKGSFLTKKQDQA 1168
Query: 3141 VNSVICIQRWFRARLQEKRFIQKYHSI 3167
++ R R R++E + Q+ +
Sbjct: 1169 ARKIMRFLRRCRHRMRELKQNQELEGL 1195
Score = 43.1 bits (100), Expect = 0.005
Identities = 28/98 (28%), Positives = 51/98 (52%), Gaps = 5/98 (5%)
Query: 2332 REMHRAATFIQSTFRMHRLHMRYQALKQASVVIQQQYQANRAAK---LQRQHYLRQRHSA 2388
RE++ AA IQ+ FR ++ + + A+ VIQ+ Y+ + L+ Y + +A
Sbjct: 1046 RELYEAARVIQTAFRKYKGRRLKEQQEVAAAVIQRCYRKYKQLTWIALKFALYKKMTQAA 1105
Query: 2389 VILQAAFRGMKTRRHLKSMHSSATLIQSRFRSLLVRRR 2426
+++Q+ FR ++ + +A LIQ +RS RRR
Sbjct: 1106 ILIQSKFRSYYEQKRFQQSRRAAVLIQQHYRS--YRRR 1141
Score = 43.1 bits (100), Expect = 0.005
Identities = 29/88 (32%), Positives = 49/88 (55%), Gaps = 8/88 (9%)
Query: 1540 AAIQLQAAFRRLKAHNLCRQIR-AACVIQSYWRMRQD----RVRFLNLKK---TIIKFQA 1591
AA +Q AFR+ K L Q AA VIQ +R + ++F KK I Q+
Sbjct: 1051 AARVIQTAFRKYKGRRLKEQQEVAAAVIQRCYRKYKQLTWIALKFALYKKMTQAAILIQS 1110
Query: 1592 HVRKHQQRQKYKKMKKAAVIIQTHFRAY 1619
R + +++++++ ++AAV+IQ H+R+Y
Sbjct: 1111 KFRSYYEQKRFQQSRRAAVLIQQHYRSY 1138
Score = 42.7 bits (99), Expect = 0.006
Identities = 27/96 (28%), Positives = 47/96 (48%), Gaps = 3/96 (3%)
Query: 2041 KDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKITNH---QHKEYLNLKKTA 2097
++ +AA IQ+ +R YK ++ +A +IQR YR K + Y + + A
Sbjct: 1046 RELYEAARVIQTAFRKYKGRRLKEQQEVAAAVIQRCYRKYKQLTWIALKFALYKKMTQAA 1105
Query: 2098 IKIQSVYRGIRVRRHIQHMHRAATFIKAMFKMHQSR 2133
I IQS +R ++ Q RAA I+ ++ ++ R
Sbjct: 1106 ILIQSKFRSYYEQKRFQQSRRAAVLIQQHYRSYRRR 1141
Score = 42.4 bits (98), Expect = 0.008
Identities = 34/111 (30%), Positives = 55/111 (49%), Gaps = 19/111 (17%)
Query: 2262 MHIAATLIQRRFRTLMMRRRFLSLKKTAILIQRKYRAHLCTKHHLQFLQVQNAVIKIQSS 2321
++ AA +IQ FR RR + A +IQR YR + L ++ ++ A+ K
Sbjct: 1048 LYEAARVIQTAFRKYKGRRLKEQQEVAAAVIQRCYRKY----KQLTWIALKFALYK---- 1099
Query: 2322 YRRWMIRKRMREMHRAATFIQSTFRMHRLHMRYQALKQASVVIQQQYQANR 2372
+M +AA IQS FR + R+Q ++A+V+IQQ Y++ R
Sbjct: 1100 -----------KMTQAAILIQSKFRSYYEQKRFQQSRRAAVLIQQHYRSYR 1139
Score = 41.6 bits (96), Expect = 0.014
Identities = 38/156 (24%), Positives = 75/156 (48%), Gaps = 15/156 (9%)
Query: 2080 IKITNHQHKEYLNLKKTAIKIQSVYRGIRVRRHIQHMHRAATFIKAMFKMHQSRI----- 2134
+ +++H+ +E L + A IQ+ +R + RR + AA I+ ++ ++
Sbjct: 1038 LTLSDHEQRE---LYEAARVIQTAFRKYKGRRLKEQQEVAAAVIQRCYRKYKQLTWIALK 1094
Query: 2135 --SYHTMRKAAIVIQVRCRAYYQGKMQREKYLTILKAVKVLQASFRGVRVRRTLRKMQTA 2192
Y M +AAI+IQ + R+YY+ K ++ +A ++Q +R R RR +T+
Sbjct: 1095 FALYKKMTQAAILIQSKFRSYYEQK----RFQQSRRAAVLIQQHYRSYR-RRPGPPHRTS 1149
Query: 2193 ATLIQSNYRRYRQQTYFNKLKKITKTVQQRYWAMKE 2228
ATL N + + +KI + +++ M+E
Sbjct: 1150 ATLPARNKGSFLTKKQDQAARKIMRFLRRCRHRMRE 1185
Score = 41.6 bits (96), Expect = 0.014
Identities = 28/102 (27%), Positives = 49/102 (48%), Gaps = 3/102 (2%)
Query: 1670 VSKKEFLSLKNATIKLQSTVKMKQTRKQYLHLRAAALFIQQCYRSKKIA---AQKREEYM 1726
+S E L A +Q+ + + R+ AA IQ+CYR K A K Y
Sbjct: 1040 LSDHEQRELYEAARVIQTAFRKYKGRRLKEQQEVAAAVIQRCYRKYKQLTWIALKFALYK 1099
Query: 1727 QMRESCIKLQAFVRGYLVRKQMRLQRKAVISLQSYFRMRKAR 1768
+M ++ I +Q+ R Y +K+ + R+A + +Q ++R + R
Sbjct: 1100 KMTQAAILIQSKFRSYYEQKRFQQSRRAAVLIQQHYRSYRRR 1141
Score = 41.2 bits (95), Expect = 0.018
Identities = 23/91 (25%), Positives = 49/91 (53%), Gaps = 3/91 (3%)
Query: 2862 AAITLQHYFRTWQTRKQFLLYRKAAVVLQNHYRAFLSAKH---QRQVYLQIRSSVIIIQA 2918
AA +Q FR ++ R+ AA V+Q YR + + +Y ++ + I+IQ+
Sbjct: 1051 AARVIQTAFRKYKGRRLKEQQEVAAAVIQRCYRKYKQLTWIALKFALYKKMTQAAILIQS 1110
Query: 2919 RSKGFIQKRKFQEIKNSTIKIQAMWRRYRAK 2949
+ + + ++++FQ+ + + + IQ +R YR +
Sbjct: 1111 KFRSYYEQKRFQQSRRAAVLIQQHYRSYRRR 1141
Score = 40.8 bits (94), Expect = 0.024
Identities = 28/87 (32%), Positives = 41/87 (47%), Gaps = 3/87 (3%)
Query: 1758 LQSYFRMRKARQYYLKMYKAIIVIQNYYHAYKAQVNQRKNFLQVKK---AATCLQAAYRG 1814
+Q+ FR K R+ + A VIQ Y YK F KK AA +Q+ +R
Sbjct: 1055 IQTAFRKYKGRRLKEQQEVAAAVIQRCYRKYKQLTWIALKFALYKKMTQAAILIQSKFRS 1114
Query: 1815 YKVRQLIKQQSIAALKIQSAFRGYNKR 1841
Y ++ +Q AA+ IQ +R Y +R
Sbjct: 1115 YYEQKRFQQSRRAAVLIQQHYRSYRRR 1141
Score = 40.0 bits (92), Expect = 0.040
Identities = 43/160 (26%), Positives = 73/160 (45%), Gaps = 17/160 (10%)
Query: 1621 FAMKVLASYQKTR--SAVIVLQSAYRGMQARKMYIHILTSVIKIQSYYRAYVSKKEFLSL 1678
FA+ L+ +++ A V+Q+A+R + R++ + IQ YR Y + +++L
Sbjct: 1035 FALLTLSDHEQRELYEAARVIQTAFRKYKGRRLKEQQEVAAAVIQRCYRKY-KQLTWIAL 1093
Query: 1679 K--------NATIKLQSTVKMKQTRKQYLHLRAAALFIQQCYRSKKIAAQKREEYMQMRE 1730
K A I +QS + +K++ R AA+ IQQ YRS +R R
Sbjct: 1094 KFALYKKMTQAAILIQSKFRSYYEQKRFQQSRRAAVLIQQHYRS-----YRRRPGPPHRT 1148
Query: 1731 SCIKLQAFVRGYLVRKQMRLQRKAVISL-QSYFRMRKARQ 1769
S +L +KQ + RK + L + RMR+ +Q
Sbjct: 1149 SATLPARNKGSFLTKKQDQAARKIMRFLRRCRHRMRELKQ 1188
Score = 40.0 bits (92), Expect = 0.040
Identities = 33/118 (27%), Positives = 53/118 (44%), Gaps = 15/118 (12%)
Query: 1596 HQQRQKYKKMKKAAVIIQTHFRAYIFAMKVLASYQKTRSAVIVLQSAYRGMQAR------ 1649
H+QR+ Y+ AA +IQT FR Y K ++ A V+Q YR +
Sbjct: 1043 HEQRELYE----AARVIQTAFRKY----KGRRLKEQQEVAAAVIQRCYRKYKQLTWIALK 1094
Query: 1650 -KMYIHILTSVIKIQSYYRAYVSKKEFLSLKNATIKLQSTVKMKQTRKQYLHLRAAAL 1706
+Y + + I IQS +R+Y +K F + A + +Q + + R H +A L
Sbjct: 1095 FALYKKMTQAAILIQSKFRSYYEQKRFQQSRRAAVLIQQHYRSYRRRPGPPHRTSATL 1152
Score = 37.7 bits (86), Expect = 0.20
Identities = 28/94 (29%), Positives = 48/94 (51%), Gaps = 1/94 (1%)
Query: 2973 EYLAILKAVKIIQGCFYTKLERTRFLNVRASAIIIQRKWRAILPAK-IAHEHFLMIKRHR 3031
E + +A ++IQ F R +A +IQR +R IA + L K +
Sbjct: 1044 EQRELYEAARVIQTAFRKYKGRRLKEQQEVAAAVIQRCYRKYKQLTWIALKFALYKKMTQ 1103
Query: 3032 AACLIQAHYRGYKGRQVFLRQKSAALIIQKYIRA 3065
AA LIQ+ +R Y ++ F + + AA++IQ++ R+
Sbjct: 1104 AAILIQSKFRSYYEQKRFQQSRRAAVLIQQHYRS 1137
Score = 36.6 bits (83), Expect = 0.45
Identities = 25/107 (23%), Positives = 52/107 (48%), Gaps = 19/107 (17%)
Query: 1493 IIQKRFRCFQAQKLYKRRKESILTIQKYYKAYLKGKIERTNYLQKRAAAIQLQAAFRRLK 1552
+IQ FR ++ ++L ++++ + IQ+ Y+ Y K+ I L+ A +
Sbjct: 1054 VIQTAFRKYKGRRLKEQQEVAAAVIQRCYRKY------------KQLTWIALKFALYK-- 1099
Query: 1553 AHNLCRQIRAACVIQSYWRMRQDRVRFLNLKKTIIKFQAHVRKHQQR 1599
+ +AA +IQS +R ++ RF ++ + Q H R +++R
Sbjct: 1100 -----KMTQAAILIQSKFRSYYEQKRFQQSRRAAVLIQQHYRSYRRR 1141
Score = 34.3 bits (77), Expect = 2.2
Identities = 39/176 (22%), Positives = 73/176 (41%), Gaps = 31/176 (17%)
Query: 2686 QNMHRAATLIQSFYRMHRAKVDYETKKTAIVVIQNYYRLYVRVKTERKNFLAVQKSVRTI 2745
+ ++ AA +IQ+ +R ++ + E ++ A VIQ YR Y ++ F +K +
Sbjct: 1046 RELYEAARVIQTAFRKYKGRRLKEQQEVAAAVIQRCYRKYKQLTWIALKFALYKKMTQ-- 1103
Query: 2746 QAAFRGMKVRQKLKNVSEEKMAAIVNQSALCCYRSKTQYEAVQSEGVMIQEWYKASGLAC 2805
AAI+ QS Y + +++ + V+IQ+ Y++
Sbjct: 1104 ---------------------AAILIQSKFRSYYEQKRFQQSRRAAVLIQQHYRSYR--- 1139
Query: 2806 SQEAEYHSQSRAAVTIQKAFCRMVTRKLETQKCAALRIQFFLQMAVYRRRFVQQKR 2861
+ H S K +T+K Q AA +I FL+ +R R ++Q +
Sbjct: 1140 RRPGPPHRTSATLPARNKG--SFLTKK---QDQAARKIMRFLRRCRHRMRELKQNQ 1190
>gi|5032281 dystrophin Dp427c isoform [Homo sapiens]
Length = 3677
Score = 57.0 bits (136), Expect = 3e-07
Identities = 60/209 (28%), Positives = 95/209 (45%), Gaps = 51/209 (24%)
Query: 965 VTNLAVDLQCGVRLVRTMELLTQNWDLSKKLRIPAISRLQKMHNVDIVLQVLKSRGIELS 1024
+ NL DLQ G RL+ +E LT K + +R+ ++NV+ L+VL++ ++L
Sbjct: 29 IENLFSDLQDGRRLLDLLEGLTGQ----KLPKEKGSTRVHALNNVNKALRVLQNNNVDLV 84
Query: 1025 DEHGNTILSKDIVDRHREKTLRLLWKIAFAFQVDISLNLDQLKEEIAFLKHTKSIKKTIS 1084
+ I S DIVD + + TL L+W I +QV + +K +A L+ T S
Sbjct: 85 N-----IGSTDIVDGNHKLTLGLIWNIILHWQVK-----NVMKNIMAGLQQTNS------ 128
Query: 1085 LLSCHSDDLINKKKGKRDSGSFEQYSENIKLLMDWVNAVCAFYNK-KVENFTVSFSDGRV 1143
K+L+ WV Y + V NFT S+SDG
Sbjct: 129 ----------------------------EKILLSWVRQSTRNYPQVNVINFTTSWSDGLA 160
Query: 1144 LCYLIHHYHPCYVPFDA-ICQRT-TQTVE 1170
L LIH + P +++ +CQ++ TQ +E
Sbjct: 161 LNALIHSHRPDLFDWNSVVCQQSATQRLE 189
>gi|5032287 dystrophin Dp427p1 isoform [Homo sapiens]
Length = 3681
Score = 57.0 bits (136), Expect = 3e-07
Identities = 60/209 (28%), Positives = 95/209 (45%), Gaps = 51/209 (24%)
Query: 965 VTNLAVDLQCGVRLVRTMELLTQNWDLSKKLRIPAISRLQKMHNVDIVLQVLKSRGIELS 1024
+ NL DLQ G RL+ +E LT K + +R+ ++NV+ L+VL++ ++L
Sbjct: 33 IENLFSDLQDGRRLLDLLEGLTGQ----KLPKEKGSTRVHALNNVNKALRVLQNNNVDLV 88
Query: 1025 DEHGNTILSKDIVDRHREKTLRLLWKIAFAFQVDISLNLDQLKEEIAFLKHTKSIKKTIS 1084
+ I S DIVD + + TL L+W I +QV + +K +A L+ T S
Sbjct: 89 N-----IGSTDIVDGNHKLTLGLIWNIILHWQVK-----NVMKNIMAGLQQTNS------ 132
Query: 1085 LLSCHSDDLINKKKGKRDSGSFEQYSENIKLLMDWVNAVCAFYNK-KVENFTVSFSDGRV 1143
K+L+ WV Y + V NFT S+SDG
Sbjct: 133 ----------------------------EKILLSWVRQSTRNYPQVNVINFTTSWSDGLA 164
Query: 1144 LCYLIHHYHPCYVPFDA-ICQRT-TQTVE 1170
L LIH + P +++ +CQ++ TQ +E
Sbjct: 165 LNALIHSHRPDLFDWNSVVCQQSATQRLE 193
>gi|5032283 dystrophin Dp427m isoform [Homo sapiens]
Length = 3685
Score = 57.0 bits (136), Expect = 3e-07
Identities = 60/209 (28%), Positives = 95/209 (45%), Gaps = 51/209 (24%)
Query: 965 VTNLAVDLQCGVRLVRTMELLTQNWDLSKKLRIPAISRLQKMHNVDIVLQVLKSRGIELS 1024
+ NL DLQ G RL+ +E LT K + +R+ ++NV+ L+VL++ ++L
Sbjct: 37 IENLFSDLQDGRRLLDLLEGLTGQ----KLPKEKGSTRVHALNNVNKALRVLQNNNVDLV 92
Query: 1025 DEHGNTILSKDIVDRHREKTLRLLWKIAFAFQVDISLNLDQLKEEIAFLKHTKSIKKTIS 1084
+ I S DIVD + + TL L+W I +QV + +K +A L+ T S
Sbjct: 93 N-----IGSTDIVDGNHKLTLGLIWNIILHWQVK-----NVMKNIMAGLQQTNS------ 136
Query: 1085 LLSCHSDDLINKKKGKRDSGSFEQYSENIKLLMDWVNAVCAFYNK-KVENFTVSFSDGRV 1143
K+L+ WV Y + V NFT S+SDG
Sbjct: 137 ----------------------------EKILLSWVRQSTRNYPQVNVINFTTSWSDGLA 168
Query: 1144 LCYLIHHYHPCYVPFDA-ICQRT-TQTVE 1170
L LIH + P +++ +CQ++ TQ +E
Sbjct: 169 LNALIHSHRPDLFDWNSVVCQQSATQRLE 197
>gi|110611228 utrophin [Homo sapiens]
Length = 3433
Score = 57.0 bits (136), Expect = 3e-07
Identities = 75/318 (23%), Positives = 126/318 (39%), Gaps = 97/318 (30%)
Query: 965 VTNLAVDLQCGVRLVRTMELLTQNWDLSKKLRIPAISRLQKMHNVDIVLQVLKSRGIELS 1024
+ ++ DL+ G +L+ +E LT L K+ +R+ ++NV+ VLQVL +EL
Sbjct: 53 INDMFTDLKDGRKLLDLLEGLTGT-SLPKER---GSTRVHALNNVNRVLQVLHQNNVELV 108
Query: 1025 DEHGNTILSKDIVDRHREKTLRLLWKIAFAFQVDISLNLDQLKEEIAFLKHTKSIKKTIS 1084
+ G DIVD + + TL LLW I +QV D +K+ ++ L+ T S
Sbjct: 109 NIGGT-----DIVDGNHKLTLGLLWSIILHWQVK-----DVMKDVMSDLQQTNS------ 152
Query: 1085 LLSCHSDDLINKKKGKRDSGSFEQYSENIKLLMDWVNAVCAFYNK-KVENFTVSFSDGRV 1143
K+L+ WV Y++ V NFT S++DG
Sbjct: 153 ----------------------------EKILLSWVRQTTRPYSQVNVLNFTTSWTDGLA 184
Query: 1144 LCYLIHHYHPCYVPFDAICQRTTQTVECTQTGSVVLNSSSESDDSSLDMSLKAFDHENTS 1203
++H + P +D + + S ++ AF
Sbjct: 185 FNAVLHRHKPDLFSWDKVVKM-----------------------SPIERLEHAF------ 215
Query: 1204 ELYKELLENEKKNFHLVRSAVRDLGGIPAMINHSDMSNTIPDEKVVITYLSFLCARLLDL 1263
S + GI +++ D++ +PD+K +I YL+ L +L
Sbjct: 216 ------------------SKAQTYLGIEKLLDPEDVAVQLPDKKSIIMYLTSL-FEVLPQ 256
Query: 1264 RKEIRAARLIQTTWRKYK 1281
+ I A R ++T RKYK
Sbjct: 257 QVTIDAIREVETLPRKYK 274
>gi|44889481 myosin IB isoform 2 [Homo sapiens]
Length = 1078
Score = 55.8 bits (133), Expect = 7e-07
Identities = 42/134 (31%), Positives = 68/134 (50%), Gaps = 20/134 (14%)
Query: 3033 ACLIQAHYRGYKGRQVFLRQKSAALIIQKYIRAREAGKHERIKYIEFKKSTVILQALVRG 3092
A LIQ YRG+K R FL K + ++I + R K +Y + K S +++Q+ +RG
Sbjct: 708 ATLIQKIYRGWKCRTHFLLMKKSQIVIAAWYRRYAQQK----RYQQTKSSALVIQSYIRG 763
Query: 3093 WLVRK--RFLEQRAKIRLLHFTAAAYYHLNAVRIQRAYKLYLAVKNANKQVNSVICIQRW 3150
W RK R L+ + + + T AAY+H +++R Y+ + NA K++
Sbjct: 764 WKARKILRELKHQKRCKEAVTTIAAYWH--GTQVRREYRKFFRA-NAGKKI--------- 811
Query: 3151 FRARLQEKRFIQKY 3164
+ LQ R +QKY
Sbjct: 812 YEFTLQ--RIVQKY 823
Score = 54.3 bits (129), Expect = 2e-06
Identities = 37/143 (25%), Positives = 69/143 (48%), Gaps = 16/143 (11%)
Query: 1864 LHDTRTHFLKTKAAVISLQSAYRGWKVRKQIRREHQAALKIQSAFRMAKAQKQFRLFKTA 1923
L D R L+ A +I Q YRGWK R ++ + I + +R QK+++ K++
Sbjct: 696 LEDLRKQRLEDLATLI--QKIYRGWKCRTHFLLMKKSQIVIAAWYRRYAQQKRYQQTKSS 753
Query: 1924 ALVIQQNFRAWTAGR--KQCMEYIELRHAVLVLQSMWKGKTLRRQLQRQHKCAIIIQSYY 1981
ALVIQ R W A + ++ + AV + + W G +RR+ ++ ++
Sbjct: 754 ALVIQSYIRGWKARKILRELKHQKRCKEAVTTIAAYWHGTQVRREYRK----------FF 803
Query: 1982 RMHVQQKKWKIMKKAALLIQKYY 2004
R + +K ++ + ++QKY+
Sbjct: 804 RANAGKKIYEFTLQR--IVQKYF 824
Score = 53.9 bits (128), Expect = 3e-06
Identities = 36/123 (29%), Positives = 68/123 (55%), Gaps = 13/123 (10%)
Query: 1955 QSMWKGKTLRRQLQRQHKCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYRAYSIGREQN 2014
++++K + LR+Q R A +IQ YR + + +MKK+ ++I +YR Y+ Q
Sbjct: 691 RTLFKLEDLRKQ--RLEDLATLIQKIYRGWKCRTHFLLMKKSQIVIAAWYRRYA----QQ 744
Query: 2015 HLYLKTKAAVVTLQSAYRGMKVRKRIKD------CNKAAVTIQSKYRAYKTKKKYAT-YR 2067
Y +TK++ + +QS RG K RK +++ C +A TI + + + +++Y +R
Sbjct: 745 KRYQQTKSSALVIQSYIRGWKARKILRELKHQKRCKEAVTTIAAYWHGTQVRREYRKFFR 804
Query: 2068 ASA 2070
A+A
Sbjct: 805 ANA 807
Score = 53.5 bits (127), Expect = 4e-06
Identities = 73/303 (24%), Positives = 119/303 (39%), Gaps = 101/303 (33%)
Query: 1334 KLLMLKKEKLEKVQNKAASLIQGYWRRYSTRQRFLKLKYYSIILQSRIRMIIAVTSYKRY 1393
KL L+K++LE + A+LIQ +R + R FL +K I++
Sbjct: 695 KLEDLRKQRLEDL----ATLIQKIYRGWKCRTHFLLMKKSQIVIA--------------- 735
Query: 1394 LWATVTIQRHWRAYLRRKQDQQRYEMLKSSTLIIQSMFRKWKQRKMQSQVKATVILQRAF 1453
A+ RR Q+RY+ KSS L+IQS R WK RK+
Sbjct: 736 ------------AWYRRYAQQKRYQQTKSSALVIQSYIRGWKARKI-------------L 770
Query: 1454 REWHLRKQAKEENSAIIIQSWY--RMHKELRKYIYIRSCVVIIQKRFRCFQAQKLYKRRK 1511
RE +K+ KE + I W+ ++ +E RK+ FR +K+Y+
Sbjct: 771 RELKHQKRCKEAVTTIAAY-WHGTQVRREYRKF-------------FRANAGKKIYEFTL 816
Query: 1512 ESILTIQKYYKAYLKGKIERTNYLQKRAAA---IQLQAAFRRLKAHNLCRQIRAACVIQS 1568
+ I +QKY+ +K K+ + + K + + L + + LK I
Sbjct: 817 QRI--VQKYF-LEMKNKMPSLSPIDKNWPSRPYLFLDSTHKELKR------------IFH 861
Query: 1569 YWRMRQDRVRFLNLKKTIIK-----------------------FQAHVRKHQQRQKYKKM 1605
WR ++ R +F + +K I + FQ + + KYKK+
Sbjct: 862 LWRCKKYRDQFTDQQKLIYEEKLEASELFKDKKALYPSSVGQPFQGAYLEINKNPKYKKL 921
Query: 1606 KKA 1608
K A
Sbjct: 922 KDA 924
Score = 53.1 bits (126), Expect = 5e-06
Identities = 46/182 (25%), Positives = 89/182 (48%), Gaps = 10/182 (5%)
Query: 1563 ACVIQSYWRMRQDRVRFLNLKKTIIKFQAHVRKHQQRQKYKKMKKAAVIIQTHFRAYIF- 1621
A +IQ +R + R FL +KK+ I A R++ Q+++Y++ K +A++IQ++ R +
Sbjct: 708 ATLIQKIYRGWKCRTHFLLMKKSQIVIAAWYRRYAQQKRYQQTKSSALVIQSYIRGWKAR 767
Query: 1622 -AMKVLASYQKTRSAVIVLQSAYRGMQARKMYIHILTSVI--KIQSYYRAYVSKKEFLSL 1678
++ L ++ + AV + + + G Q R+ Y + KI + + +K FL +
Sbjct: 768 KILRELKHQKRCKEAVTTIAAYWHGTQVRREYRKFFRANAGKKIYEFTLQRIVQKYFLEM 827
Query: 1679 KNATIKLQSTVKMKQTRKQYLHLRAAALFIQQCY---RSKKIAAQKREEYMQMRESCIKL 1735
KN L S + + YL L + +++ + R KK Q ++ + E KL
Sbjct: 828 KNKMPSL-SPIDKNWPSRPYLFLDSTHKELKRIFHLWRCKKYRDQFTDQQKLIYEE--KL 884
Query: 1736 QA 1737
+A
Sbjct: 885 EA 886
Score = 51.2 bits (121), Expect = 2e-05
Identities = 30/98 (30%), Positives = 53/98 (54%), Gaps = 4/98 (4%)
Query: 1947 LRHAVLVLQSMWKGKTLRRQLQRQHKCAIIIQSYYRMHVQQKKWKIMKKAALLIQKY--- 2003
L ++Q +++G R K I+I ++YR + QQK+++ K +AL+IQ Y
Sbjct: 704 LEDLATLIQKIYRGWKCRTHFLLMKKSQIVIAAWYRRYAQQKRYQQTKSSALVIQSYIRG 763
Query: 2004 YRAYSIGREQNHLYLKTKAAVVTLQSAYRGMKVRKRIK 2041
++A I RE H + K AV T+ + + G +VR+ +
Sbjct: 764 WKARKILRELKH-QKRCKEAVTTIAAYWHGTQVRREYR 800
Score = 50.4 bits (119), Expect = 3e-05
Identities = 29/95 (30%), Positives = 46/95 (48%), Gaps = 2/95 (2%)
Query: 2027 LQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKITN-- 2084
+Q YRG K R K+ + I + YR Y +K+Y ++SA++IQ + RG K
Sbjct: 711 IQKIYRGWKCRTHFLLMKKSQIVIAAWYRRYAQQKRYQQTKSSALVIQSYIRGWKARKIL 770
Query: 2085 HQHKEYLNLKKTAIKIQSVYRGIRVRRHIQHMHRA 2119
+ K K+ I + + G +VRR + RA
Sbjct: 771 RELKHQKRCKEAVTTIAAYWHGTQVRREYRKFFRA 805
Score = 48.1 bits (113), Expect = 1e-04
Identities = 41/142 (28%), Positives = 64/142 (45%), Gaps = 20/142 (14%)
Query: 2007 YSIGREQNHLYLKTKAAVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYATY 2066
YS GR + ++++ + L+ + +R++D A IQ YR +K + +
Sbjct: 678 YSFGRSK--IFIRNPRTLFKLEDLRK-----QRLEDL---ATLIQKIYRGWKCRTHFLLM 727
Query: 2067 RASAIIIQRWYRGIKITNHQHKEYLNLKKTAIKIQSVYRGIRVR---RHIQHMHR---AA 2120
+ S I+I WYR Q K Y K +A+ IQS RG + R R ++H R A
Sbjct: 728 KKSQIVIAAWYRRYA----QQKRYQQTKSSALVIQSYIRGWKARKILRELKHQKRCKEAV 783
Query: 2121 TFIKAMFKMHQSRISYHTMRKA 2142
T I A + Q R Y +A
Sbjct: 784 TTIAAYWHGTQVRREYRKFFRA 805
Score = 47.8 bits (112), Expect = 2e-04
Identities = 43/178 (24%), Positives = 77/178 (43%), Gaps = 8/178 (4%)
Query: 1800 QVKKAATCLQAAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRVKYQSVLQSIIKIQRWYR 1859
+++ AT +Q YRG+K R + + I + +R Y ++ +YQ S + IQ + R
Sbjct: 703 RLEDLATLIQKIYRGWKCRTHFLLMKKSQIVIAAWYRRYAQQKRYQQTKSSALVIQSYIR 762
Query: 1860 AYKTLHDTR--THFLKTKAAVISLQSAYRGWKVRKQIRR--EHQAALKIQSAFRMAKAQK 1915
+K R H + K AV ++ + + G +VR++ R+ A KI QK
Sbjct: 763 GWKARKILRELKHQKRCKEAVTTIAAYWHGTQVRREYRKFFRANAGKKIYEFTLQRIVQK 822
Query: 1916 QFRLFKTAALVIQQNFRAWTAGRKQCMEYIELRHAVLV-LQSMWKGKTLRRQLQRQHK 1972
F K + + W + + +++ H L + +W+ K R Q Q K
Sbjct: 823 YFLEMKNKMPSLSPIDKNWPS---RPYLFLDSTHKELKRIFHLWRCKKYRDQFTDQQK 877
Score = 47.0 bits (110), Expect = 3e-04
Identities = 32/98 (32%), Positives = 50/98 (51%), Gaps = 2/98 (2%)
Query: 2093 LKKTAIKIQSVYRGIRVRRHIQHMHRAATFIKAMFKMHQSRISYHTMRKAAIVIQVRCRA 2152
L+ A IQ +YRG + R H M ++ I A ++ + + Y + +A+VIQ R
Sbjct: 704 LEDLATLIQKIYRGWKCRTHFLLMKKSQIVIAAWYRRYAQQKRYQQTKSSALVIQSYIRG 763
Query: 2153 YYQGKMQRE-KYLTILK-AVKVLQASFRGVRVRRTLRK 2188
+ K+ RE K+ K AV + A + G +VRR RK
Sbjct: 764 WKARKILRELKHQKRCKEAVTTIAAYWHGTQVRREYRK 801
Score = 47.0 bits (110), Expect = 3e-04
Identities = 42/187 (22%), Positives = 83/187 (44%), Gaps = 29/187 (15%)
Query: 1735 LQAFVRGYLVRKQMRLQRKAVISLQSYFRMRKARQYYLKMYKAIIVIQNYYHAYKAQ--V 1792
+Q RG+ R L +K+ I + +++R ++ Y + + +VIQ+Y +KA+ +
Sbjct: 711 IQKIYRGWKCRTHFLLMKKSQIVIAAWYRRYAQQKRYQQTKSSALVIQSYIRGWKARKIL 770
Query: 1793 NQRKNFLQVKKAATCLQAAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRVKYQSVLQSII 1852
+ K+ + K+A T + A + G +VR+ + + FR + Y+ LQ I+
Sbjct: 771 RELKHQKRCKEAVTTIAAYWHGTQVRR----------EYRKFFRANAGKKIYEFTLQRIV 820
Query: 1853 KIQRWYRAYKTLHDTRTHFLKTKAAVISLQSAYRGWKVRKQIRRE--HQAALKIQSAFRM 1910
+ +FL+ K + SL + W R + + H+ +I +R
Sbjct: 821 ---------------QKYFLEMKNKMPSLSPIDKNWPSRPYLFLDSTHKELKRIFHLWRC 865
Query: 1911 AKAQKQF 1917
K + QF
Sbjct: 866 KKYRDQF 872
Score = 46.6 bits (109), Expect = 4e-04
Identities = 27/90 (30%), Positives = 52/90 (57%), Gaps = 2/90 (2%)
Query: 2672 IQSYYRGFKVRKDIQNMHRAATLIQSFYRMHRAKVDYETKKTAIVVIQNYYRLYV--RVK 2729
IQ YRG+K R M ++ +I ++YR + + Y+ K++ +VIQ+Y R + ++
Sbjct: 711 IQKIYRGWKCRTHFLLMKKSQIVIAAWYRRYAQQKRYQQTKSSALVIQSYIRGWKARKIL 770
Query: 2730 TERKNFLAVQKSVRTIQAAFRGMKVRQKLK 2759
E K+ +++V TI A + G +VR++ +
Sbjct: 771 RELKHQKRCKEAVTTIAAYWHGTQVRREYR 800
Score = 45.1 bits (105), Expect = 0.001
Identities = 51/219 (23%), Positives = 94/219 (42%), Gaps = 34/219 (15%)
Query: 2863 AITLQHYFRTWQTRKQFLLYRKAAVVLQNHYRAFLSAKHQRQVYLQIRSSVIIIQARSKG 2922
A +Q +R W+ R FLL +K+ +V+ YR + Q++ Y Q +SS ++IQ+ +G
Sbjct: 708 ATLIQKIYRGWKCRTHFLLMKKSQIVIAAWYRRYA----QQKRYQQTKSSALVIQSYIRG 763
Query: 2923 FIQKRKFQEIKNSTIKIQAMWRRYRAKKYLCKVKAACKIQAWYRCWRAHKEYLAILK--A 2980
+ ++ +E+K+ + CK +A I A++ + +EY + A
Sbjct: 764 WKARKILRELKH---------------QKRCK-EAVTTIAAYWHGTQVRREYRKFFRANA 807
Query: 2981 VKIIQGCFYTKLERTRFL---NVRASAIIIQRKWRAILPAKIAHEHFLMIKRHRAACLIQ 3037
K I ++ + FL N S I + W + + + H+ I
Sbjct: 808 GKKIYEFTLQRIVQKYFLEMKNKMPSLSPIDKNWP-------SRPYLFLDSTHKELKRIF 860
Query: 3038 AHYRGYKGRQVFLRQKSAALIIQKYIRAREAGKHERIKY 3076
+R K R F Q+ LI ++ + A E K ++ Y
Sbjct: 861 HLWRCKKYRDQFTDQQK--LIYEEKLEASELFKDKKALY 897
Score = 44.3 bits (103), Expect = 0.002
Identities = 52/194 (26%), Positives = 86/194 (44%), Gaps = 27/194 (13%)
Query: 1259 RLLDLRKEIRA--ARLIQTTWRKYKLKTDLKRHQEREKAARIIQLAVINFLAKQ-RLRKR 1315
+L DLRK+ A LIQ +R +K +T H K ++I+ A A+Q R ++
Sbjct: 695 KLEDLRKQRLEDLATLIQKIYRGWKCRT----HFLLMKKSQIVIAAWYRRYAQQKRYQQT 750
Query: 1316 VNAALVIQKYWRRVLAQRKLLMLKKEKLEKVQNKAASLIQGYWRRYSTRQRFLKL----- 1370
++ALVIQ Y R A++ L LK +K K +A + I YW R+ + K
Sbjct: 751 KSSALVIQSYIRGWKARKILRELKHQKRCK---EAVTTIAAYWHGTQVRREYRKFFRANA 807
Query: 1371 --KYYSIILQSRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQRYEMLKSSTLIIQ 1428
K Y LQ ++ K + + I ++W + Y L S+ ++
Sbjct: 808 GKKIYEFTLQRIVQKYF--LEMKNKMPSLSPIDKNW--------PSRPYLFLDSTHKELK 857
Query: 1429 SMFRKWKQRKMQSQ 1442
+F W+ +K + Q
Sbjct: 858 RIFHLWRCKKYRDQ 871
Score = 44.3 bits (103), Expect = 0.002
Identities = 29/126 (23%), Positives = 58/126 (46%), Gaps = 4/126 (3%)
Query: 2310 QVQNAVIKIQSSYRRWMIRKRMREMHRAATFIQSTFRMHRLHMRYQALKQASVVIQQQYQ 2369
++++ IQ YR W R M ++ I + +R + RYQ K +++VIQ +
Sbjct: 703 RLEDLATLIQKIYRGWKCRTHFLLMKKSQIVIAAWYRRYAQQKRYQQTKSSALVIQSYIR 762
Query: 2370 ANRAAKLQRQ--HYLRQRHSAVILQAAFRGMKTRRHLKSMH--SSATLIQSRFRSLLVRR 2425
+A K+ R+ H R + + + A + G + RR + ++ I +V++
Sbjct: 763 GWKARKILRELKHQKRCKEAVTTIAAYWHGTQVRREYRKFFRANAGKKIYEFTLQRIVQK 822
Query: 2426 RFISLK 2431
F+ +K
Sbjct: 823 YFLEMK 828
Score = 42.7 bits (99), Expect = 0.006
Identities = 24/80 (30%), Positives = 40/80 (50%), Gaps = 4/80 (5%)
Query: 2686 QNMHRAATLIQSFYRMHRAKVDYETKKTAIVVIQNYYRLYVRVKTERKNFLAVQKSVRTI 2745
Q + ATLIQ YR + + + K + +VI +YR Y ++K + + S I
Sbjct: 702 QRLEDLATLIQKIYRGWKCRTHFLLMKKSQIVIAAWYRRY----AQQKRYQQTKSSALVI 757
Query: 2746 QAAFRGMKVRQKLKNVSEEK 2765
Q+ RG K R+ L+ + +K
Sbjct: 758 QSYIRGWKARKILRELKHQK 777
Score = 42.4 bits (98), Expect = 0.008
Identities = 32/147 (21%), Positives = 66/147 (44%), Gaps = 23/147 (15%)
Query: 1630 QKTRSAVIVLQSAYRGMQARKMYIHILTSVIKIQSYYRAYVSKKEFLSLKNATIKLQSTV 1689
Q+ ++Q YRG + R ++ + S I I ++YR Y +K + K++ + +QS +
Sbjct: 702 QRLEDLATLIQKIYRGWKCRTHFLLMKKSQIVIAAWYRRYAQQKRYQQTKSSALVIQSYI 761
Query: 1690 KMKQTRKQYLHLRAAALFIQQCYRSKKIAAQKREEYMQMRESCIKLQAFVRGYLVRKQMR 1749
+ + RK +++ QKR +E+ + A+ G VR++ R
Sbjct: 762 RGWKARKIL----------------RELKHQKR-----CKEAVTTIAAYWHGTQVRREYR 800
Query: 1750 --LQRKAVISLQSYFRMRKARQYYLKM 1774
+ A + + R ++Y+L+M
Sbjct: 801 KFFRANAGKKIYEFTLQRIVQKYFLEM 827
Score = 40.8 bits (94), Expect = 0.024
Identities = 27/106 (25%), Positives = 49/106 (46%), Gaps = 3/106 (2%)
Query: 2235 RYNKLRHSVIYIQAIFRGKKARRHLKMMHIAATLIQRRFRTLMMRRRFLSLKKTAILIQ- 2293
R +L IQ I+RG K R H +M + +I +R ++R+ K +A++IQ
Sbjct: 700 RKQRLEDLATLIQKIYRGWKCRTHFLLMKKSQIVIAAWYRRYAQQKRYQQTKSSALVIQS 759
Query: 2294 --RKYRAHLCTKHHLQFLQVQNAVIKIQSSYRRWMIRKRMREMHRA 2337
R ++A + + + AV I + + +R+ R+ RA
Sbjct: 760 YIRGWKARKILRELKHQKRCKEAVTTIAAYWHGTQVRREYRKFFRA 805
Score = 39.7 bits (91), Expect = 0.053
Identities = 33/121 (27%), Positives = 59/121 (48%), Gaps = 16/121 (13%)
Query: 2114 QHMHRAATFIKAMFKMHQSRISYHTMRKAAIVIQVRCRAYYQGKMQREKYLTILKAVKVL 2173
Q + AT I+ +++ + R + M+K+ IVI A+Y+ Q+++Y + V+
Sbjct: 702 QRLEDLATLIQKIYRGWKCRTHFLLMKKSQIVIA----AWYRRYAQQKRYQQTKSSALVI 757
Query: 2174 QASFRGVRVRRTLRKM------QTAATLIQSNY------RRYRQQTYFNKLKKITKTVQQ 2221
Q+ RG + R+ LR++ + A T I + + R YR+ N KKI + Q
Sbjct: 758 QSYIRGWKARKILRELKHQKRCKEAVTTIAAYWHGTQVRREYRKFFRANAGKKIYEFTLQ 817
Query: 2222 R 2222
R
Sbjct: 818 R 818
Score = 39.3 bits (90), Expect = 0.069
Identities = 39/188 (20%), Positives = 82/188 (43%), Gaps = 14/188 (7%)
Query: 2451 LYQFLHLRKAAITIQSSYRRLMVKKKLQEMQR-------AAVLIQATFRMYRTYITFQTW 2503
L + + +R+A + +Y + + K+ Q A ++ F + ++
Sbjct: 621 LLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPARSGVEVLFNELEIPVEEYSF 680
Query: 2504 KHASILIQQHYRTYRAAKLQRENYIRQWHSAVVIQAAYKGMKARQLLREKHKASIVIQST 2563
+ I I+ ++ L+++ R A +IQ Y+G K R K+ IVI +
Sbjct: 681 GRSKIFIRNPRTLFKLEDLRKQ---RLEDLATLIQKIYRGWKCRTHFLLMKKSQIVIAAW 737
Query: 2564 YRMYRQYCFYQKLQWATKIIQEKYRANKKKQ--KVFQHNELKKE--TCVQAGFQDMNIKK 2619
YR Y Q YQ+ + + +IQ R K ++ + +H + KE T + A + +++
Sbjct: 738 YRRYAQQKRYQQTKSSALVIQSYIRGWKARKILRELKHQKRCKEAVTTIAAYWHGTQVRR 797
Query: 2620 QIQEQHQA 2627
+ ++ +A
Sbjct: 798 EYRKFFRA 805
Score = 38.9 bits (89), Expect = 0.090
Identities = 25/98 (25%), Positives = 47/98 (47%), Gaps = 11/98 (11%)
Query: 2622 QEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQRRYRKLTAVR-----TQAVICIQSYY 2676
Q A +IQK + +K R H+L ++ + + I YR+ + + + IQSY
Sbjct: 702 QRLEDLATLIQKIYRGWKCRTHFLLMKKSQIVIAAWYRRYAQQKRYQQTKSSALVIQSYI 761
Query: 2677 RGFKVRKDIQNM------HRAATLIQSFYRMHRAKVDY 2708
RG+K RK ++ + A T I +++ + + +Y
Sbjct: 762 RGWKARKILRELKHQKRCKEAVTTIAAYWHGTQVRREY 799
Score = 38.5 bits (88), Expect = 0.12
Identities = 36/170 (21%), Positives = 66/170 (38%), Gaps = 26/170 (15%)
Query: 2172 VLQASFRGVRVRRTLRKMQTAATLIQSNYRRYRQQTYFNKLKKITKTVQQRYWAMKERNI 2231
++Q +RG + R M+ + +I + YRRY QQ + + K +Q K R I
Sbjct: 710 LIQKIYRGWKCRTHFLLMKKSQIVIAAWYRRYAQQKRYQQTKSSALVIQSYIRGWKARKI 769
Query: 2232 --QFQRYNKLRHSVIYIQAIFRGKKARRHLKMMHIA-----------ATLIQRRFRTLMM 2278
+ + + + +V I A + G + RR + A ++Q+ F +
Sbjct: 770 LRELKHQKRCKEAVTTIAAYWHGTQVRREYRKFFRANAGKKIYEFTLQRIVQKYFLEMKN 829
Query: 2279 R-------------RRFLSLKKTAILIQRKYRAHLCTKHHLQFLQVQNAV 2315
+ R +L L T ++R + C K+ QF Q +
Sbjct: 830 KMPSLSPIDKNWPSRPYLFLDSTHKELKRIFHLWRCKKYRDQFTDQQKLI 879
Score = 37.0 bits (84), Expect = 0.34
Identities = 26/111 (23%), Positives = 49/111 (44%), Gaps = 2/111 (1%)
Query: 2375 KLQRQHYLRQRHSAVILQAAFRGMKTRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKAT 2434
KL+ R A ++Q +RG K R H M S +I + +R ++R+ K +
Sbjct: 695 KLEDLRKQRLEDLATLIQKIYRGWKCRTHFLLMKKSQIVIAAWYRRYAQQKRYQQTKSSA 754
Query: 2435 IFVQRKYRATICAK--HKLYQFLHLRKAAITIQSSYRRLMVKKKLQEMQRA 2483
+ +Q R K +L ++A TI + + V+++ ++ RA
Sbjct: 755 LVIQSYIRGWKARKILRELKHQKRCKEAVTTIAAYWHGTQVRREYRKFFRA 805
Score = 36.6 bits (83), Expect = 0.45
Identities = 30/135 (22%), Positives = 58/135 (42%), Gaps = 12/135 (8%)
Query: 2849 MAVYRRRFVQQKR------AAITLQHYFRTWQTRKQFLLYR-----KAAVVLQNHYRAFL 2897
+A + RR+ QQKR +A+ +Q Y R W+ RK + K AV Y
Sbjct: 734 IAAWYRRYAQQKRYQQTKSSALVIQSYIRGWKARKILRELKHQKRCKEAVTTIAAYWHGT 793
Query: 2898 SAKHQRQVYLQIRSSVIIIQARSKGFIQKRKFQEIKNSTIKIQAMWRRYRAKKYLCKVKA 2957
+ + + + + + I + + +QK F E+KN + + + + ++ YL
Sbjct: 794 QVRREYRKFFRANAGKKIYEFTLQRIVQK-YFLEMKNKMPSLSPIDKNWPSRPYLFLDST 852
Query: 2958 ACKIQAWYRCWRAHK 2972
+++ + WR K
Sbjct: 853 HKELKRIFHLWRCKK 867
>gi|170014684 IQ motif containing B1 isoform a [Homo sapiens]
Length = 598
Score = 55.5 bits (132), Expect = 9e-07
Identities = 63/262 (24%), Positives = 116/262 (44%), Gaps = 39/262 (14%)
Query: 1561 RAACVIQSYWRMRQDRVRFLNLKKTIIKFQAHVRKHQ-------QRQKYKKMKKAAVIIQ 1613
+AAC+IQ+YW+ Q R R L +I Q R + RQK ++ K + +Q
Sbjct: 296 QAACLIQAYWKGFQTRKRLKKLPSAVIALQRSFRSKRSKMLLEINRQKEEEDLKLQLQLQ 355
Query: 1614 THFRAYIFAMKVLASYQKTRSAVI---VLQSAYRGMQARKMYIHILTSVIKIQSYYRAYV 1670
AM++ Q + ++ ++ YR M+ + S + IQ ++R Y
Sbjct: 356 RQ-----RAMRLSRELQLSMLEIVHPGQVEKHYREMEEK--------SALIIQKHWRGYR 402
Query: 1671 SKKEFLSLKNATIKLQSTVKMKQTRKQYLHLRAAALFIQQCYRSKKIAAQKR--EEYMQM 1728
+K F + + I+ ++ V ++ RAA F+ +C + KK+ A R +E
Sbjct: 403 ERKNFHQQRQSLIEYKAAVTLQ---------RAALKFLAKCRKKKKLFAPWRGLQELTDA 453
Query: 1729 RESCIKLQAFVRGYLVRKQMRLQRKAVISLQSYFRMRKARQYYLKMYKAIIVIQNYYHAY 1788
R ++L+ V Y VR+ + V+S + + + ++ Q+Y Q + A
Sbjct: 454 RR--VELKKRVDDY-VRRHLGSPMSDVVSRELHAQAQERLQHYFMGRALEERAQQHREAL 510
Query: 1789 KAQVNQRKNFLQVKKAATCLQA 1810
AQ++ N Q+ KA + +A
Sbjct: 511 IAQIS--TNVEQLMKAPSLKEA 530
Score = 50.8 bits (120), Expect = 2e-05
Identities = 39/140 (27%), Positives = 74/140 (52%), Gaps = 8/140 (5%)
Query: 1678 LKNATIKLQSTVKMKQTRKQYLHLRAAALFIQQCYRSKKIAAQKREEYMQMRESCIKLQA 1737
L A +Q+ K QTRK+ L +A + +Q+ +RSK+ + E Q E +KLQ
Sbjct: 294 LHQAACLIQAYWKGFQTRKRLKKLPSAVIALQRSFRSKR-SKMLLEINRQKEEEDLKLQL 352
Query: 1738 FVRGYLVRKQMRLQRKAVISLQSYFRMRKARQYYLKM-YKAIIVIQNYYHAYKAQVN--- 1793
++ ++ MRL R+ +S+ + ++Y +M K+ ++IQ ++ Y+ + N
Sbjct: 353 QLQR---QRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKHWRGYRERKNFHQ 409
Query: 1794 QRKNFLQVKKAATCLQAAYR 1813
QR++ ++ K A T +AA +
Sbjct: 410 QRQSLIEYKAAVTLQRAALK 429
Score = 48.5 bits (114), Expect = 1e-04
Identities = 52/210 (24%), Positives = 102/210 (48%), Gaps = 29/210 (13%)
Query: 1849 QSIIKIQRWYRAYKTLH------DTRTHFLKTKAAVISLQSAYRGWKVRKQIRREHQAAL 1902
Q I+ + R YK L +T T F + ++ L S +V +Q + HQAA
Sbjct: 242 QEILILLRQSTCYKGLRRLLSKQETGTEFSQELRQLVGLLSPMVYQEVEEQ--KLHQAAC 299
Query: 1903 KIQSAFRMAKAQKQFRLFKTAALVIQQNFRAWTAGRKQCMEYIELRHAVLVLQSMWKGKT 1962
IQ+ ++ + +K+ + +A + +Q++FR+ K+ +E+ Q +
Sbjct: 300 LIQAYWKGFQTRKRLKKLPSAVIALQRSFRS-----KRSKMLLEINR-----QKEEEDLK 349
Query: 1963 LRRQLQRQHKCAI-------IIQSYYRMHVQQKKWKIMKKAALLIQKYYRAYSIGR---E 2012
L+ QLQRQ + +++ + V++ ++ +K+AL+IQK++R Y + +
Sbjct: 350 LQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKHWRGYRERKNFHQ 409
Query: 2013 QNHLYLKTKAAVVTLQSAYRGM-KVRKRIK 2041
Q ++ KAAV ++A + + K RK+ K
Sbjct: 410 QRQSLIEYKAAVTLQRAALKFLAKCRKKKK 439
Score = 48.1 bits (113), Expect = 1e-04
Identities = 47/143 (32%), Positives = 70/143 (48%), Gaps = 27/143 (18%)
Query: 1337 MLKKEKLEKVQNKAASLIQGYWRRYSTRQRFLKLKYYSIILQ-----SRIRMIIAVTSYK 1391
M+ +E E+ ++AA LIQ YW+ + TR+R KL I LQ R +M++ + K
Sbjct: 284 MVYQEVEEQKLHQAACLIQAYWKGFQTRKRLKKLPSAVIALQRSFRSKRSKMLLEINRQK 343
Query: 1392 RY--LWATVTIQRHWRAYLRRK------------QDQQRY-EMLKSSTLIIQSMFRKWKQ 1436
L + +QR L R+ Q ++ Y EM + S LIIQ +R +++
Sbjct: 344 EEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKHWRGYRE 403
Query: 1437 RK-----MQS--QVKATVILQRA 1452
RK QS + KA V LQRA
Sbjct: 404 RKNFHQQRQSLIEYKAAVTLQRA 426
Score = 48.1 bits (113), Expect = 1e-04
Identities = 47/180 (26%), Positives = 84/180 (46%), Gaps = 14/180 (7%)
Query: 1720 QKREEYMQMRESCIKLQAFVRGYLVRKQMRLQRKAVISLQSYFRMRKARQYYLKMYKAII 1779
Q+ EE + +C+ +QA+ +G+ RK+++ AVI+LQ FR ++++ L++ +
Sbjct: 287 QEVEEQKLHQAACL-IQAYWKGFQTRKRLKKLPSAVIALQRSFRSKRSKM-LLEINR--- 341
Query: 1780 VIQNYYHAYKAQV---NQRKNFLQVKKAATCLQAAYRGYKVRQLIKQQSIAALKIQSAFR 1836
Q K Q+ QR L + + L+ + G + + + +AL IQ +R
Sbjct: 342 --QKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKHWR 399
Query: 1837 GYNKRVKYQSVLQSIIKIQRWYRAYKTLHDTRTHFLKTKAAVISLQSAYRGWKVRKQIRR 1896
GY +R + QS+I+ Y+A TL FL L + +RG + RR
Sbjct: 400 GYRERKNFHQQRQSLIE----YKAAVTLQRAALKFLAKCRKKKKLFAPWRGLQELTDARR 455
Score = 47.0 bits (110), Expect = 3e-04
Identities = 53/250 (21%), Positives = 115/250 (46%), Gaps = 45/250 (18%)
Query: 2970 AHKEYLAILKAVKIIQGCFYTKLERTRFLNVRASAIIIQRKWRAI--LPAKIAHEHFLMI 3027
+H+E L +L+ +G R L+ + + ++ R + L + + ++
Sbjct: 240 SHQEILILLRQSTCYKGL-------RRLLSKQETGTEFSQELRQLVGLLSPMVYQEVEEQ 292
Query: 3028 KRHRAACLIQAHYRGYKGRQVFLRQKSAALIIQKYIRAREAGKHERIKYIEFKKSTVILQ 3087
K H+AACLIQA+++G++ R+ + SA + +Q+ R++ + + + I +K L+
Sbjct: 293 KLHQAACLIQAYWKGFQTRKRLKKLPSAVIALQRSFRSK---RSKMLLEINRQKEEEDLK 349
Query: 3088 ALVRGWLVRKRFLEQRAKIRLLHFTAAAYYHLNAVRIQRAYKLYLAVKNANKQVNSVICI 3147
++ R L + ++ +L ++ ++++ Y+ + S + I
Sbjct: 350 LQLQLQRQRAMRLSRELQLSMLEI-------VHPGQVEKHYR--------EMEEKSALII 394
Query: 3148 QRWFRARLQEKRFIQKYHSIKKIEHEGQECLSQRNRAASVIQKAVRHFLLRKKQEKFTSG 3207
Q+ +R + K F Q+ S+ IE+ +AA +Q+A FL + +++K
Sbjct: 395 QKHWRGYRERKNFHQQRQSL--IEY----------KAAVTLQRAALKFLAKCRKKK---- 438
Query: 3208 IIKIQALWRG 3217
K+ A WRG
Sbjct: 439 --KLFAPWRG 446
Score = 45.1 bits (105), Expect = 0.001
Identities = 45/243 (18%), Positives = 111/243 (45%), Gaps = 14/243 (5%)
Query: 1413 DQQRYEMLKSSTLIIQSMFRKWKQRKMQSQVKATVILQRAFREWHLRKQ-AKEENSAIII 1471
D+ +++ + + +I+S K +S + ++L+++ LR+ +K+E
Sbjct: 212 DEVIFKLFSTPSPVIRSTATKLLLLMAESHQEILILLRQSTCYKGLRRLLSKQETGTEFS 271
Query: 1472 QSWYRMHKELRKYIY-------IRSCVVIIQKRFRCFQAQKLYKRRKESILTIQKYYKAY 1524
Q ++ L +Y + +IQ ++ FQ +K K+ +++ +Q+ +++
Sbjct: 272 QELRQLVGLLSPMVYQEVEEQKLHQAACLIQAYWKGFQTRKRLKKLPSAVIALQRSFRSK 331
Query: 1525 LKGKIERTNYLQKRAAAIQLQAAFRRLKAHNLCRQIRAACVIQSYWRMRQDRVRFLNLKK 1584
+ N QK ++LQ +R +A L R+++ + + + + R + K
Sbjct: 332 RSKMLLEIN-RQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKS 390
Query: 1585 TIIKFQAHVRKHQQRQKYKKMKKAAVIIQTHFRAYIFAMKVLASYQKTRSAVIVLQSAYR 1644
+I Q H R +++R+ + + +++ + + A+K LA +K + L + +R
Sbjct: 391 ALI-IQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRKKKK----LFAPWR 445
Query: 1645 GMQ 1647
G+Q
Sbjct: 446 GLQ 448
Score = 44.7 bits (104), Expect = 0.002
Identities = 45/232 (19%), Positives = 111/232 (47%), Gaps = 14/232 (6%)
Query: 2405 KSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKHKLYQFLHLRKAA--I 2462
+ +H +A LIQ+ ++ R+R L A I +QR +R+ + K+ ++ +K +
Sbjct: 292 QKLHQAACLIQAYWKGFQTRKRLKKLPSAVIALQRSFRS---KRSKMLLEINRQKEEEDL 348
Query: 2463 TIQSSYRRLMVKKKLQEMQRAAVLIQATFRMYRTYITFQTWKHASILIQQHYRTYRAAKL 2522
+Q +R + +E+Q + + I ++ + Y + + ++++IQ+H+R YR
Sbjct: 349 KLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREME--EKSALIIQKHWRGYR---- 402
Query: 2523 QRENYIRQWHSAVVIQAAYKGMKARQLLREKHKASIVIQSTYRMYRQYCFYQKLQWATKI 2582
+R+N+ +Q S + +AA +A K + + + +R ++ ++++ ++
Sbjct: 403 ERKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRKKKKLFAPWRGLQELTDARRVELKKRV 462
Query: 2583 --IQEKYRANKKKQKVFQHNELKKETCVQAGFQDMNIKKQIQEQHQAAIIIQ 2632
++ + V + + + +Q F ++++ Q QH+ A+I Q
Sbjct: 463 DDYVRRHLGSPMSDVVSRELHAQAQERLQHYFMGRALEERAQ-QHREALIAQ 513
Score = 44.3 bits (103), Expect = 0.002
Identities = 57/272 (20%), Positives = 120/272 (44%), Gaps = 32/272 (11%)
Query: 2601 ELKKETCVQAGFQDMNIKKQIQEQ--HQAAIIIQKHCKAFKIRKHYLHLRATVVSIQRRY 2658
E +E G + ++++EQ HQAA +IQ + K F+ RK L + V+++QR +
Sbjct: 269 EFSQELRQLVGLLSPMVYQEVEEQKLHQAACLIQAYWKGFQTRKRLKKLPSAVIALQRSF 328
Query: 2659 RKLTAVRTQAVICIQSYYRGFKVRKDIQNMHRAATLIQSFYRMHRAKVDYETKKTAIVVI 2718
R + R++ ++ I ++ +Q + A + ++ ++ + + +
Sbjct: 329 R---SKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQ------V 379
Query: 2719 QNYYRLYVRVKTERKNFLAVQKSVRTIQAAFRGMKVRQKLKNVSEEKMAAIVNQSALCCY 2778
+ +YR + E K+ L +QK +RG + R KN +++ + I ++A+
Sbjct: 380 EKHYR-----EMEEKSALIIQKH-------WRGYRER---KNFHQQRQSLIEYKAAVTLQ 424
Query: 2779 RSKTQYEA-VQSEGVMIQEWYKASGLACSQEAEYHSQSRAAVT--IQKAFCRMVTRKLET 2835
R+ ++ A + + + W L ++ E + V + +V+R+L
Sbjct: 425 RAALKFLAKCRKKKKLFAPWRGLQELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHA 484
Query: 2836 QKCAALRIQFFLQMAVYRRRFVQQKRAAITLQ 2867
Q L+ +F+ A+ R QQ R A+ Q
Sbjct: 485 QAQERLQ-HYFMGRALEER--AQQHREALIAQ 513
Score = 42.4 bits (98), Expect = 0.008
Identities = 45/198 (22%), Positives = 87/198 (43%), Gaps = 39/198 (19%)
Query: 2280 RRFLSLKKTAILIQRKYRAHLCTKHHLQFLQVQN-----AVIKIQSSYRRWMIRKRMREM 2334
RR LS ++T ++ R + + + +V+ A IQ+ ++ + RKR++++
Sbjct: 258 RRLLSKQETGTEFSQELRQLVGLLSPMVYQEVEEQKLHQAACLIQAYWKGFQTRKRLKKL 317
Query: 2335 HRAATFIQSTFRMHRLHMRYQALKQAS---VVIQQQYQANRAAKLQRQ------------ 2379
A +Q +FR R M + +Q + +Q Q Q RA +L R+
Sbjct: 318 PSAVIALQRSFRSKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPG 377
Query: 2380 ----HYLR-QRHSAVILQAAFRGMKTRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKAT 2434
HY + SA+I+Q +RG + R++ +SL+ + ++L++A
Sbjct: 378 QVEKHYREMEEKSALIIQKHWRGYRERKNFHQQR----------QSLIEYKAAVTLQRAA 427
Query: 2435 IFVQRKYRATICAKHKLY 2452
+ K+ A K KL+
Sbjct: 428 L----KFLAKCRKKKKLF 441
Score = 38.9 bits (89), Expect = 0.090
Identities = 49/241 (20%), Positives = 101/241 (41%), Gaps = 35/241 (14%)
Query: 1946 ELRHAVLVLQSMWKGKTLRRQLQRQHKCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYR 2005
ELR V +L M + + Q+ H+ A +IQ+Y++ +K+ K + A + +Q+ +R
Sbjct: 273 ELRQLVGLLSPMVYQEV---EEQKLHQAACLIQAYWKGFQTRKRLKKLPSAVIALQRSFR 329
Query: 2006 A------YSIGRE--------------QNHLYLKTKAAVVTLQSAYRGMKVRKRIKDC-N 2044
+ I R+ Q + L + + L+ + G +V K ++
Sbjct: 330 SKRSKMLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPG-QVEKHYREMEE 388
Query: 2045 KAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKITNHQHKEYLNLKKTAIKIQSVY 2104
K+A+ IQ +R Y+ +K + R S I Y+ ++L + K+ + +
Sbjct: 389 KSALIIQKHWRGYRERKNFHQQRQSLI----EYKAAVTLQRAALKFLAKCRKKKKLFAPW 444
Query: 2105 RGIRV---RRHIQHMHRAATFIKAMFKMHQSRISYHTMRKAAIVIQVRCRAYYQGKMQRE 2161
RG++ R ++ R +++ S + + A Q R + Y+ G+ E
Sbjct: 445 RGLQELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQA---QERLQHYFMGRALEE 501
Query: 2162 K 2162
+
Sbjct: 502 R 502
Score = 38.9 bits (89), Expect = 0.090
Identities = 44/162 (27%), Positives = 73/162 (45%), Gaps = 23/162 (14%)
Query: 2828 MVTRKLETQKC--AALRIQFFLQMAVYRRRFVQQKRAAITLQHYFRTWQTRK-------- 2877
MV +++E QK AA IQ + + R+R + A I LQ FR+ +++
Sbjct: 284 MVYQEVEEQKLHQAACLIQAYWKGFQTRKRLKKLPSAVIALQRSFRSKRSKMLLEINRQK 343
Query: 2878 -------QFLLYRKAAVVLQNHYR-AFLSAKHQRQVYLQIRS----SVIIIQARSKGFIQ 2925
Q L R+ A+ L + + L H QV R S +IIQ +G+ +
Sbjct: 344 EEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKHWRGYRE 403
Query: 2926 KRKFQEIKNSTIKIQAMWRRYRAK-KYLCKVKAACKIQAWYR 2966
++ F + + S I+ +A RA K+L K + K+ A +R
Sbjct: 404 RKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRKKKKLFAPWR 445
Score = 38.5 bits (88), Expect = 0.12
Identities = 31/137 (22%), Positives = 66/137 (48%), Gaps = 17/137 (12%)
Query: 2168 KAVKVLQASFRGVRVRRTLRKMQTAATLIQSNYRRYRQQTYFNKLKKITKTVQQRYWAMK 2227
+A ++QA ++G + R+ L+K+ +A +Q ++R R K + + +Q+
Sbjct: 296 QAACLIQAYWKGFQTRKRLKKLPSAVIALQRSFRSKRS-------KMLLEINRQKEEEDL 348
Query: 2228 ERNIQFQRYNKLRHS----VIYIQAIFRGKKARRHLKMMHIAATLIQRRFRTLMMRRRF- 2282
+ +Q QR +R S + ++ + G+ + + +M +A +IQ+ +R R+ F
Sbjct: 349 KLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKHWRGYRERKNFH 408
Query: 2283 -----LSLKKTAILIQR 2294
L K A+ +QR
Sbjct: 409 QQRQSLIEYKAAVTLQR 425
Score = 37.7 bits (86), Expect = 0.20
Identities = 54/264 (20%), Positives = 116/264 (43%), Gaps = 26/264 (9%)
Query: 1229 GIPAMINHSDMSNTIPDE-KVVITYLSFLCARLLDLRKEIRAARLIQTTWRKYKLKTDLK 1287
G+ +++ + E + ++ LS + + ++ +K +AA LIQ W+ ++ + LK
Sbjct: 256 GLRRLLSKQETGTEFSQELRQLVGLLSPMVYQEVEEQKLHQAACLIQAYWKGFQTRKRLK 315
Query: 1288 R-------HQEREKAARIIQLAVINFLAKQRLRKRVNAALVIQKY-WRRVLAQRKLLMLK 1339
+ Q ++ R L IN +Q+ + + L +Q+ R+ + +L ML+
Sbjct: 316 KLPSAVIALQRSFRSKRSKMLLEIN---RQKEEEDLKLQLQLQRQRAMRLSRELQLSMLE 372
Query: 1340 -------KEKLEKVQNKAASLIQGYWRRYSTRQRFLKLKYYSIILQSRIRMIIAVTSYKR 1392
++ +++ K+A +IQ +WR Y R+ F + + I ++ + + A +
Sbjct: 373 IVHPGQVEKHYREMEEKSALIIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLA 432
Query: 1393 YLWATVTIQRHWRAYLRRKQDQQRYEMLKSSTLIIQ----SMFRKWKQRKMQSQVKATVI 1448
+ WR L+ D +R E+ K ++ S R++ +Q +
Sbjct: 433 KCRKKKKLFAPWRG-LQELTDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQER-- 489
Query: 1449 LQRAFREWHLRKQAKEENSAIIIQ 1472
LQ F L ++A++ A+I Q
Sbjct: 490 LQHYFMGRALEERAQQHREALIAQ 513
Score = 37.0 bits (84), Expect = 0.34
Identities = 29/133 (21%), Positives = 66/133 (49%), Gaps = 4/133 (3%)
Query: 2925 QKRKFQEIKNSTIKIQAMWRRYRAKKYLCKVKAACKIQAWYRCWRAHKEYLAILKAVKII 2984
Q+ + Q++ + IQA W+ ++ +K L K+ +A + A R +R+ + + + +
Sbjct: 287 QEVEEQKLHQAACLIQAYWKGFQTRKRLKKLPSA--VIALQRSFRSKRSKMLLEINRQKE 344
Query: 2985 QGCFYTKLERTRFLNVRASAIIIQRKWRAILPAKIAHEHFLMIKRHRAACLIQAHYRGYK 3044
+ +L+ R +R S + + P ++ + M ++A +IQ H+RGY+
Sbjct: 345 EEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREM--EEKSALIIQKHWRGYR 402
Query: 3045 GRQVFLRQKSAAL 3057
R+ F +Q+ + +
Sbjct: 403 ERKNFHQQRQSLI 415
Score = 37.0 bits (84), Expect = 0.34
Identities = 34/145 (23%), Positives = 62/145 (42%), Gaps = 18/145 (12%)
Query: 2238 KLRHSVIYIQAIFRGKKARRHLKMMHIAATLIQRRFRTL-------MMRRRFLSLKKTAI 2290
KL + IQA ++G + R+ LK + A +QR FR+ + R++ K +
Sbjct: 293 KLHQAACLIQAYWKGFQTRKRLKKLPSAVIALQRSFRSKRSKMLLEINRQKEEEDLKLQL 352
Query: 2291 LIQRKYRAHLCTKHHLQFLQVQNAVIKIQSSYRRWMIRKRMREM-HRAATFIQSTFRMHR 2349
+QR+ L + L L++ + + K REM ++A IQ +R +R
Sbjct: 353 QLQRQRAMRLSRELQLSMLEIVHP----------GQVEKHYREMEEKSALIIQKHWRGYR 402
Query: 2350 LHMRYQALKQASVVIQQQYQANRAA 2374
+ +Q+ + + RAA
Sbjct: 403 ERKNFHQQRQSLIEYKAAVTLQRAA 427
Score = 36.6 bits (83), Expect = 0.45
Identities = 31/134 (23%), Positives = 65/134 (48%), Gaps = 6/134 (4%)
Query: 2908 QIRSSVIIIQARSKGFIQKRKFQEIKNSTIKIQAMWRRYRAKKYL----CKVKAACKIQA 2963
++ + +IQA KGF +++ +++ ++ I +Q +R R+K L K + K+Q
Sbjct: 293 KLHQAACLIQAYWKGFQTRKRLKKLPSAVIALQRSFRSKRSKMLLEINRQKEEEDLKLQL 352
Query: 2964 WYRCWRAHKEYLAILKAVKIIQGCFYTKLERTRFLNVRASAIIIQRKWRAILPAKIAHEH 3023
+ RA + L+ + +++ ++E+ SA+IIQ+ WR K H+
Sbjct: 353 QLQRQRAMR--LSRELQLSMLEIVHPGQVEKHYREMEEKSALIIQKHWRGYRERKNFHQQ 410
Query: 3024 FLMIKRHRAACLIQ 3037
+ ++AA +Q
Sbjct: 411 RQSLIEYKAAVTLQ 424
>gi|154354979 myosin X [Homo sapiens]
Length = 2058
Score = 54.7 bits (130), Expect = 2e-06
Identities = 69/333 (20%), Positives = 135/333 (40%), Gaps = 59/333 (17%)
Query: 2301 CTKHHLQFL--QVQNAVIKIQSSYRRWMIRKRMREMHRAATF-IQSTFRMHRLHMRYQAL 2357
C K ++Q + Q AV+ Q Y + R+R+ A Q ++ +++ MR AL
Sbjct: 636 CIKPNMQKMPDQFDQAVVLNQLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKVLMRNLAL 695
Query: 2358 KQ----ASVVIQQQYQANRAA----------------KLQRQHYLRQRHSAVILQAAFRG 2397
+ + Q Y A+ + KL+++ H+A++++A G
Sbjct: 696 PEDVRGKCTSLLQLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVLG 755
Query: 2398 MKTRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKHKLYQFLHL 2457
R+ + + +IQ +R+ L+RRRF+ LKKA I Q++ R I +
Sbjct: 756 FLARKQYRKVLYCVVIIQKNYRAFLLRRRFLHLKKAAIVFQKQLRGQIARR--------- 806
Query: 2458 RKAAITIQSSYRRLMVKKKLQEMQRAAVLIQATFRMYRTYITFQTWKHASILIQQHYRTY 2517
YR+L+ +K+ QE ++ + R + + A + QQ T
Sbjct: 807 ---------VYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEETR 857
Query: 2518 RAAKLQRENYIRQWHSAVVIQAAYKGMKARQLLR--EKHKASIVIQSTYRMYRQYCFYQK 2575
+ +L +A K K +L R EK K + ++ R+ ++ Q+
Sbjct: 858 KQQEL---------------EALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQR 902
Query: 2576 LQWATKIIQEKYRANKKKQKVFQH-NELKKETC 2607
++ ++ + K +++ Q L++E C
Sbjct: 903 MKEQQELSLTEASLQKLQERRDQELRRLEEEAC 935
Score = 54.7 bits (130), Expect = 2e-06
Identities = 47/199 (23%), Positives = 91/199 (45%), Gaps = 16/199 (8%)
Query: 2228 ERNIQFQRYNKLRHSVIYIQAIFRGKKARRHLKMMHIAATLIQRRFRTLMMRRRFLSLKK 2287
E+ ++ +R ++ H+ + I+A G AR+ + + +IQ+ +R ++RRRFL LKK
Sbjct: 731 EQKLEKRREEEVSHAAMVIRAHVLGFLARKQYRKVLYCVVIIQKNYRAFLLRRRFLHLKK 790
Query: 2288 TAILIQRKYRAHLCTKHHLQFL------QVQNAVIKIQSSYRRWMIRKRMREMHRAATFI 2341
AI+ Q++ R + + + Q L + + + + R R+R RE A
Sbjct: 791 AAIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAELRA 850
Query: 2342 QSTFRMHRLHMRYQALKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAA---FRGM 2398
Q R +AL+++ Q +A +L++Q +Q + L+ + M
Sbjct: 851 QQE-EETRKQQELEALQKS------QKEAELTRELEKQKENKQVEEILRLEKEIEDLQRM 903
Query: 2399 KTRRHLKSMHSSATLIQSR 2417
K ++ L +S +Q R
Sbjct: 904 KEQQELSLTEASLQKLQER 922
Score = 52.0 bits (123), Expect = 1e-05
Identities = 31/101 (30%), Positives = 54/101 (53%)
Query: 1630 QKTRSAVIVLQSAYRGMQARKMYIHILTSVIKIQSYYRAYVSKKEFLSLKNATIKLQSTV 1689
++ A +V+++ G ARK Y +L V+ IQ YRA++ ++ FL LK A I Q +
Sbjct: 740 EEVSHAAMVIRAHVLGFLARKQYRKVLYCVVIIQKNYRAFLLRRRFLHLKKAAIVFQKQL 799
Query: 1690 KMKQTRKQYLHLRAAALFIQQCYRSKKIAAQKREEYMQMRE 1730
+ + R+ Y L A ++ + ++ +KREE + RE
Sbjct: 800 RGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERE 840
Score = 47.8 bits (112), Expect = 2e-04
Identities = 47/198 (23%), Positives = 91/198 (45%), Gaps = 32/198 (16%)
Query: 1287 KRHQEREKAARIIQLAVINFLAKQRLRKRVNAALVIQKYWRRVLAQRKLLMLKKEKLEKV 1346
K + ++A + QL L R+RK A +++ ++ + K+LM E V
Sbjct: 643 KMPDQFDQAVVLNQLRYSGMLETVRIRK---AGYAVRRPFQDFYKRYKVLMRNLALPEDV 699
Query: 1347 QNKAASLIQGY------WR--------RYSTRQRFLK-----LKYYSIILQSRIRMIIAV 1387
+ K SL+Q Y W+ R S Q+ K + + ++++++ + +A
Sbjct: 700 RGKCTSLLQLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVLGFLAR 759
Query: 1388 TSYKRYLWATVTIQRHWRAYLRRKQDQQRYEMLKSSTLIIQSMFRKWKQRKMQSQVKATV 1447
Y++ L+ V IQ+++RA+L R+ R+ LK + ++ Q R R++ Q+ A
Sbjct: 760 KQYRKVLYCVVIIQKNYRAFLLRR----RFLHLKKAAIVFQKQLRGQIARRVYRQLLAEK 815
Query: 1448 ILQRAFREWHLRKQAKEE 1465
RE +K+ +EE
Sbjct: 816 ------REQEEKKKQEEE 827
Score = 47.4 bits (111), Expect = 3e-04
Identities = 40/155 (25%), Positives = 77/155 (49%), Gaps = 16/155 (10%)
Query: 1397 TVTIQRHWRAYLRRKQD-QQRYEMLKSSTLIIQ-------SMFRKWKQRKMQSQVKATVI 1448
TV I++ A R QD +RY++L + + + S+ + + + Q+ T +
Sbjct: 665 TVRIRKAGYAVRRPFQDFYKRYKVLMRNLALPEDVRGKCTSLLQLYDASNSEWQLGKTKV 724
Query: 1449 LQRAFREWHLRKQAKEE--NSAIIIQSW---YRMHKELRKYIYIRSCVVIIQKRFRCFQA 1503
R E L K+ +EE ++A++I++ + K+ RK +Y CVVIIQK +R F
Sbjct: 725 FLRESLEQKLEKRREEEVSHAAMVIRAHVLGFLARKQYRKVLY---CVVIIQKNYRAFLL 781
Query: 1504 QKLYKRRKESILTIQKYYKAYLKGKIERTNYLQKR 1538
++ + K++ + QK + + ++ R +KR
Sbjct: 782 RRRFLHLKKAAIVFQKQLRGQIARRVYRQLLAEKR 816
Score = 47.0 bits (110), Expect = 3e-04
Identities = 49/241 (20%), Positives = 105/241 (43%), Gaps = 23/241 (9%)
Query: 1499 RCFQA--QKLYKRRKESILTIQKYYKAYLKG-KIERTNYLQKRAAAIQLQAAFRRLKA-- 1553
RC + QK+ + ++++ Q Y L+ +I + Y +R Q ++R K
Sbjct: 635 RCIKPNMQKMPDQFDQAVVLNQLRYSGMLETVRIRKAGYAVRRP----FQDFYKRYKVLM 690
Query: 1554 HNLC--RQIRAAC--VIQSYWRMRQDRVRFLNLKKTIIKFQAHVRKHQQRQKYKKMKKAA 1609
NL +R C ++Q Y + L KT + + + + ++++ +++ AA
Sbjct: 691 RNLALPEDVRGKCTSLLQLYDASNSE----WQLGKTKVFLRESLEQKLEKRREEEVSHAA 746
Query: 1610 VIIQTHFRAYIFAMKVLASYQKTRSAVIVLQSAYRGMQARKMYIHILTSVIKIQSYYRAY 1669
++I RA++ Y+K V+++Q YR R+ ++H+ + I Q R
Sbjct: 747 MVI----RAHVLGFLARKQYRKVLYCVVIIQKNYRAFLLRRRFLHLKKAAIVFQKQLRGQ 802
Query: 1670 VSKKEFLSLKNATIKLQSTVKMKQTRKQYLHLRAAALFIQQCYRSKKIAAQKREEYMQMR 1729
++++ + L K + K KQ ++ ++ R ++ AQ+ EE + +
Sbjct: 803 IARRVYRQL--LAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEETRKQQ 860
Query: 1730 E 1730
E
Sbjct: 861 E 861
Score = 47.0 bits (110), Expect = 3e-04
Identities = 51/244 (20%), Positives = 105/244 (43%), Gaps = 51/244 (20%)
Query: 1283 KTDLKRHQEREKAARIIQLAVINFLAKQRLRKRVNAALVIQKYWRRVLAQRKLLMLKKEK 1342
K + +R +E AA +I+ V+ FLA+++ RK + ++IQK +R L +R
Sbjct: 733 KLEKRREEEVSHAAMVIRAHVLGFLARKQYRKVLYCVVIIQKNYRAFLLRR--------- 783
Query: 1343 LEKVQNKAASLIQGYWRRYSTRQRFLKLKYYSIILQSRIRMIIAVTSYKRYL-----WAT 1397
RFL LK +I+ Q ++R IA Y++ L
Sbjct: 784 -----------------------RFLHLKKAAIVFQKQLRGQIARRVYRQLLAEKREQEE 820
Query: 1398 VTIQRHWRAYLRRKQDQQRYEMLKSSTLIIQSMFRKWKQRKMQSQVKATVILQRAFREWH 1457
Q R +++++R + + L Q KQ+++++ LQ++ +E
Sbjct: 821 KKKQEEEEKKKREEEERERERERREAELRAQQEEETRKQQELEA-------LQKSQKEAE 873
Query: 1458 LRKQAKEENSAIIIQSWYRMHKELRKYIYIRSCVVIIQKRFRCFQA--QKLYKRRKESIL 1515
L ++ +++ ++ R+ KE+ ++ Q+ +A QKL +RR + +
Sbjct: 874 LTRELEKQKENKQVEEILRLEKEIEDLQRMKE-----QQELSLTEASLQKLQERRDQELR 928
Query: 1516 TIQK 1519
+++
Sbjct: 929 RLEE 932
Score = 42.0 bits (97), Expect = 0.011
Identities = 20/60 (33%), Positives = 37/60 (61%)
Query: 1946 ELRHAVLVLQSMWKGKTLRRQLQRQHKCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYR 2005
E+ HA +V+++ G R+Q ++ C +IIQ YR + ++++ +KKAA++ QK R
Sbjct: 741 EVSHAAMVIRAHVLGFLARKQYRKVLYCVVIIQKNYRAFLLRRRFLHLKKAAIVFQKQLR 800
Score = 41.6 bits (96), Expect = 0.014
Identities = 45/191 (23%), Positives = 80/191 (41%), Gaps = 33/191 (17%)
Query: 1635 AVIVLQSAYRGMQARKMYIHILTSVIK-IQSYYRAYVSKKEFLSL-KNATIKLQSTVKMK 1692
AV++ Q Y GM +V + Q +Y+ Y L+L ++ K S +++
Sbjct: 651 AVVLNQLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKVLMRNLALPEDVRGKCTSLLQLY 710
Query: 1693 QTRKQYLHLRAAALFIQQCYRSKKIAAQKREEYMQMRESCIKLQAFVRGYLVRKQMRLQR 1752
L +F+++ K ++REE ++ + + ++A V G+L RKQ
Sbjct: 711 DASNSEWQLGKTKVFLRESLEQK--LEKRREE--EVSHAAMVIRAHVLGFLARKQ----- 761
Query: 1753 KAVISLQSYFRMRKARQYYLKMYKAIIVIQNYYHAYKAQVNQRKNFLQVKKAATCLQAAY 1812
Y K+ +++IQ Y A+ R+ FL +KKAA Q
Sbjct: 762 ------------------YRKVLYCVVIIQKNYRAFLL----RRRFLHLKKAAIVFQKQL 799
Query: 1813 RGYKVRQLIKQ 1823
RG R++ +Q
Sbjct: 800 RGQIARRVYRQ 810
Score = 41.6 bits (96), Expect = 0.014
Identities = 22/86 (25%), Positives = 48/86 (55%), Gaps = 4/86 (4%)
Query: 2847 LQMAVYRRRFVQQKRAAITLQHYFRTWQTRKQFLLYRKAAVVLQNHYRAFLSAKHQRQVY 2906
L+ + +RR + AA+ ++ + + RKQ+ V++Q +YRAFL R+ +
Sbjct: 730 LEQKLEKRREEEVSHAAMVIRAHVLGFLARKQYRKVLYCVVIIQKNYRAFL----LRRRF 785
Query: 2907 LQIRSSVIIIQARSKGFIQKRKFQEI 2932
L ++ + I+ Q + +G I +R ++++
Sbjct: 786 LHLKKAAIVFQKQLRGQIARRVYRQL 811
Score = 39.7 bits (91), Expect = 0.053
Identities = 27/124 (21%), Positives = 56/124 (45%), Gaps = 9/124 (7%)
Query: 1972 KCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYRAYSIGREQNHLYLKTKAAVVTLQSAY 2031
KC ++Q Y +W++ K L + + RE+ + A + +++
Sbjct: 702 KCTSLLQLY---DASNSEWQLGKTKVFLRESLEQKLEKRREE-----EVSHAAMVIRAHV 753
Query: 2032 RGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKITNHQHKEYL 2091
G RK+ + V IQ YRA+ ++++ + +AI+ Q+ RG +I +++ L
Sbjct: 754 LGFLARKQYRKVLYCVVIIQKNYRAFLLRRRFLHLKKAAIVFQKQLRG-QIARRVYRQLL 812
Query: 2092 NLKK 2095
K+
Sbjct: 813 AEKR 816
Score = 39.3 bits (90), Expect = 0.069
Identities = 41/154 (26%), Positives = 65/154 (42%), Gaps = 17/154 (11%)
Query: 1822 KQQSIAALKIQSAFRGYNKRVKYQSVLQSIIKIQRWYRAYKTLHDTRTHFLKTKAAVISL 1881
++ S AA+ I++ G+ R +Y+ VL ++ IQ+ YRA+ R FL K A I
Sbjct: 740 EEVSHAAMVIRAHVLGFLARKQYRKVLYCVVIIQKNYRAFL----LRRRFLHLKKAAIVF 795
Query: 1882 QSAYRGWKVRKQIR-----REHQAALKIQSAFRMAKAQKQFRLFKTAALVIQQNFRAWTA 1936
Q RG R+ R + Q K Q K +++ R ++ R
Sbjct: 796 QKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEER--------ERERERREAE 847
Query: 1937 GRKQCMEYIELRHAVLVLQSMWKGKTLRRQLQRQ 1970
R Q E + + LQ K L R+L++Q
Sbjct: 848 LRAQQEEETRKQQELEALQKSQKEAELTRELEKQ 881
Score = 38.1 bits (87), Expect = 0.15
Identities = 49/224 (21%), Positives = 92/224 (41%), Gaps = 23/224 (10%)
Query: 2023 AVVTLQSAYRGMKVRKRIKDCNKAAVT-IQSKYRAYKTKKKYATYRASAIIIQRWYRG-- 2079
AVV Q Y GM RI+ A Q Y+ YK + + + RG
Sbjct: 651 AVVLNQLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKVLMRN-------LALPEDVRGKC 703
Query: 2080 ---IKITNHQHKEYLNLKKTAIKIQSVYRGIRVRRHIQHMHRAATFIKAMFKMHQSRISY 2136
+++ + + E+ L KT + ++ +R + + AA I+A +R Y
Sbjct: 704 TSLLQLYDASNSEW-QLGKTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVLGFLARKQY 762
Query: 2137 HTMRKAAIVIQVRCRAYYQGKMQREKYLTILKAVKVLQASFRGVRVRRTLRKMQTAATLI 2196
+ ++IQ RA+ + R ++L + KA V Q RG RR R++ L
Sbjct: 763 RKVLYCVVIIQKNYRAF----LLRRRFLHLKKAAIVFQKQLRGQIARRVYRQL-----LA 813
Query: 2197 QSNYRRYRQQTYFNKLKKITKTVQQRYWAMKERNIQFQRYNKLR 2240
+ + +++ + KK + ++R +E ++ Q+ + R
Sbjct: 814 EKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEETR 857
Score = 37.0 bits (84), Expect = 0.34
Identities = 42/188 (22%), Positives = 75/188 (39%), Gaps = 31/188 (16%)
Query: 1877 AVISLQSAYRGWKVRKQIRREHQAALKIQSAFRMAKAQKQFRLFKTAALVIQQNFRAWTA 1936
AV+ Q Y G +IR+ A ++ F+ F V+ +N
Sbjct: 651 AVVLNQLRYSGMLETVRIRKAGYAV------------RRPFQDFYKRYKVLMRNLALPED 698
Query: 1937 GRKQCMEYIELRHAVLVLQSMWK-GKTLRRQLQRQHKCAIIIQSYYRMHVQQKKWKIMKK 1995
R +C ++L A S W+ GKT + ++ +++++ + +
Sbjct: 699 VRGKCTSLLQLYDAS---NSEWQLGKT-----------KVFLRESLEQKLEKRREEEVSH 744
Query: 1996 AALLIQKYYRAYSIGREQNHLYLKTKAAVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYR 2055
AA++I RA+ +G Y K VV +Q YR +R+R KAA+ Q + R
Sbjct: 745 AAMVI----RAHVLGFLARKQYRKVLYCVVIIQKNYRAFLLRRRFLHLKKAAIVFQKQLR 800
Query: 2056 AYKTKKKY 2063
++ Y
Sbjct: 801 GQIARRVY 808
Score = 36.2 bits (82), Expect = 0.58
Identities = 56/286 (19%), Positives = 113/286 (39%), Gaps = 35/286 (12%)
Query: 2518 RAAKLQRENYIRQWHSAVVI-QAAYKGMKARQLLREK-HKASIVIQSTYRMY----RQYC 2571
R K + Q+ AVV+ Q Y GM +R+ + Q Y+ Y R
Sbjct: 635 RCIKPNMQKMPDQFDQAVVLNQLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKVLMRNLA 694
Query: 2572 FYQKLQWATKIIQEKYRANKK-----KQKVFQHNELKKET-------------CVQAGFQ 2613
+ ++ + + Y A+ K KVF L+++ ++A
Sbjct: 695 LPEDVRGKCTSLLQLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVL 754
Query: 2614 DMNIKKQIQEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQRRYRKLTAVRTQAVICIQ 2673
+KQ ++ +IIQK+ +AF +R+ +LHL+ + Q++ R A R + +
Sbjct: 755 GFLARKQYRKVLYCVVIIQKNYRAFLLRRRFLHLKKAAIVFQKQLRGQIARRVYRQLLAE 814
Query: 2674 SYYRGFKVRKDIQNMHRAATLIQSFYRMH-----RAKVDYETKK-TAIVVIQNYYRLYVR 2727
+ K +++ + + + R RA+ + ET+K + +Q +
Sbjct: 815 KREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEETRKQQELEALQKSQK---- 870
Query: 2728 VKTERKNFLAVQKSVRTIQAAFRGMKVRQKLKNVSEEKMAAIVNQS 2773
+ E L QK + ++ R K + L+ + E++ ++ S
Sbjct: 871 -EAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEAS 915
Score = 36.2 bits (82), Expect = 0.58
Identities = 29/149 (19%), Positives = 66/149 (44%), Gaps = 12/149 (8%)
Query: 2238 KLRHSVIYIQAIFRGKKARRHLKMMHIAATLIQRRFRTLMMRRRFLSLKKTAILIQRKYR 2297
+L + ++++ K +R + + AA +I+ + R+++ + ++IQ+ YR
Sbjct: 718 QLGKTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVLGFLARKQYRKVLYCVVIIQKNYR 777
Query: 2298 AHLCTKHHLQFLQVQNAVIKIQSS---------YRRWMIRKRMREMHRAATFIQSTFRMH 2348
A L + +FL ++ A I Q YR+ + KR +E + + R
Sbjct: 778 AFLLRR---RFLHLKKAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREE 834
Query: 2349 RLHMRYQALKQASVVIQQQYQANRAAKLQ 2377
R + ++A + QQ+ + + +L+
Sbjct: 835 EERERERERREAELRAQQEEETRKQQELE 863
Score = 36.2 bits (82), Expect = 0.58
Identities = 25/75 (33%), Positives = 41/75 (54%), Gaps = 1/75 (1%)
Query: 2957 AACKIQAWYRCWRAHKEYLAILKAVKIIQGCFYTKLERTRFLNVRASAIIIQRKWRAILP 3016
AA I+A + A K+Y +L V IIQ + L R RFL+++ +AI+ Q++ R +
Sbjct: 745 AAMVIRAHVLGFLARKQYRKVLYCVVIIQKNYRAFLLRRRFLHLKKAAIVFQKQLRGQI- 803
Query: 3017 AKIAHEHFLMIKRHR 3031
A+ + L KR +
Sbjct: 804 ARRVYRQLLAEKREQ 818
Score = 36.2 bits (82), Expect = 0.58
Identities = 21/66 (31%), Positives = 35/66 (53%), Gaps = 4/66 (6%)
Query: 2885 AAVVLQNHYRAFLSAKHQRQVYLQIRSSVIIIQARSKGFIQKRKFQEIKNSTIKIQAMWR 2944
AA+V++ H FL+ K R+V V+IIQ + F+ +R+F +K + I Q R
Sbjct: 745 AAMVIRAHVLGFLARKQYRKVLY----CVVIIQKNYRAFLLRRRFLHLKKAAIVFQKQLR 800
Query: 2945 RYRAKK 2950
A++
Sbjct: 801 GQIARR 806
Score = 34.7 bits (78), Expect = 1.7
Identities = 42/176 (23%), Positives = 75/176 (42%), Gaps = 30/176 (17%)
Query: 2902 QRQVYLQIRSSVII--IQARSKGFIQKRKFQEIKNSTIKIQAMWRRYRA--KKYLCKVKA 2957
Q V Q+R S ++ ++ R G+ +R FQ+ ++RY+ +
Sbjct: 650 QAVVLNQLRYSGMLETVRIRKAGYAVRRPFQDF----------YKRYKVLMRNLALPEDV 699
Query: 2958 ACKIQAWYRCWRAHKEYLAILKAVKIIQGCFYTKLERTRFLNVRASAIIIQRKWRAILPA 3017
K + + + A + K ++ KLE+ R V +A++I+
Sbjct: 700 RGKCTSLLQLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVSHAAMVIR--------- 750
Query: 3018 KIAHE-HFLMIKRHR----AACLIQAHYRGYKGRQVFLRQKSAALIIQKYIRAREA 3068
AH FL K++R +IQ +YR + R+ FL K AA++ QK +R + A
Sbjct: 751 --AHVLGFLARKQYRKVLYCVVIIQKNYRAFLLRRRFLHLKKAAIVFQKQLRGQIA 804
Score = 33.9 bits (76), Expect = 2.9
Identities = 20/84 (23%), Positives = 44/84 (52%)
Query: 2827 RMVTRKLETQKCAALRIQFFLQMAVYRRRFVQQKRAAITLQHYFRTWQTRKQFLLYRKAA 2886
++ R+ E AA+ I+ + + R+++ + + +Q +R + R++FL +KAA
Sbjct: 733 KLEKRREEEVSHAAMVIRAHVLGFLARKQYRKVLYCVVIIQKNYRAFLLRRRFLHLKKAA 792
Query: 2887 VVLQNHYRAFLSAKHQRQVYLQIR 2910
+V Q R ++ + RQ+ + R
Sbjct: 793 IVFQKQLRGQIARRVYRQLLAEKR 816
Score = 33.1 bits (74), Expect = 4.9
Identities = 49/189 (25%), Positives = 77/189 (40%), Gaps = 42/189 (22%)
Query: 3063 IRAREAGKHERIKYIEFKKSTVILQALVRGWLVRKRFLEQRAKIRLLHFTAAAYYHLNAV 3122
IRA G R +Y + VI+Q R +L+R+RF LH AA +
Sbjct: 749 IRAHVLGFLARKQYRKVLYCVVIIQKNYRAFLLRRRF---------LHLKKAAIVFQKQL 799
Query: 3123 RIQRAYKLYLAVKNANKQVNSVICIQRWFRARLQEKRFIQKYHSIKKIEHEGQECLSQRN 3182
R Q A ++Y Q R QE++ Q+ KK E E +E +R
Sbjct: 800 RGQIARRVYR---------------QLLAEKREQEEKKKQEEEEKKKREEEERERERERR 844
Query: 3183 RAASVIQKAVRHFLLRKKQEKFTSGIIKIQALWRGYSWRKKNDCTKIKAIRLSLQVVNRE 3242
A LR +QE+ T +++AL + +K+ + T+ L Q N++
Sbjct: 845 EAE-----------LRAQQEEETRKQQELEALQKS---QKEAELTR----ELEKQKENKQ 886
Query: 3243 IREENKLYK 3251
+ E +L K
Sbjct: 887 VEEILRLEK 895
>gi|39753961 IQ motif containing GTPase activating protein 3 [Homo
sapiens]
Length = 1631
Score = 54.7 bits (130), Expect = 2e-06
Identities = 34/102 (33%), Positives = 53/102 (51%), Gaps = 15/102 (14%)
Query: 2889 LQNHYRAFLSAKHQRQVYLQIRSSVIIIQARSKGFIQKRKFQEIKN-------STIKIQA 2941
+Q+ +A ++Q++ VI +QAR +GF+ ++KF E + + IKIQA
Sbjct: 710 IQSAVTKVTAAYDRQQLWKANVGFVIQLQARLRGFLVRQKFAEHSHFLRTWLPAVIKIQA 769
Query: 2942 MWRRYRAKK--------YLCKVKAACKIQAWYRCWRAHKEYL 2975
WR YR +K + + A KIQAW R W A ++YL
Sbjct: 770 HWRGYRQRKIYLEWLQYFKANLDAIIKIQAWARMWAARRQYL 811
Score = 49.3 bits (116), Expect = 7e-05
Identities = 42/137 (30%), Positives = 69/137 (50%), Gaps = 20/137 (14%)
Query: 1800 QVKKAATCLQAAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRVKY-------QSVLQSII 1852
+++ A T + AAY +QL K +++Q+ RG+ R K+ ++ L ++I
Sbjct: 709 EIQSAVTKVTAAYDR---QQLWKANVGFVIQLQARLRGFLVRQKFAEHSHFLRTWLPAVI 765
Query: 1853 KIQ---RWYRAYKTLHDTRTHFLKTKAAVISLQSAYRGWKVRKQ-IRREH------QAAL 1902
KIQ R YR K + +F A+I +Q+ R W R+Q +RR H + +
Sbjct: 766 KIQAHWRGYRQRKIYLEWLQYFKANLDAIIKIQAWARMWAARRQYLRRLHYFQKNVNSIV 825
Query: 1903 KIQSAFRMAKAQKQFRL 1919
KIQ+ FR KAQ +R+
Sbjct: 826 KIQAFFRARKAQDDYRI 842
Score = 43.1 bits (100), Expect = 0.005
Identities = 65/281 (23%), Positives = 109/281 (38%), Gaps = 81/281 (28%)
Query: 3021 HEHFLMIKRHRAACLIQAHYRGYKGRQVFLRQKSAALIIQKYIRAREAGKHERIKYIEFK 3080
H HFL A IQAH+RGY+ R+++L E ++Y +
Sbjct: 753 HSHFLRTWLP-AVIKIQAHWRGYRQRKIYL---------------------EWLQYFKAN 790
Query: 3081 KSTVI-LQALVRGWLVRKRFLEQRAKIRLLHFTAAAYYHLNAVRIQRAYKLYLAVKNANK 3139
+I +QA R W R+++L R LH+ K
Sbjct: 791 LDAIIKIQAWARMWAARRQYL------RRLHY-------------------------FQK 819
Query: 3140 QVNSVICIQRWFRARLQEKRFIQKYHSIKKIEHEGQECLSQRNRAASVIQKAVRHFLLRK 3199
VNS++ IQ +FRAR + + + + H LS R A ++ ++ + FL
Sbjct: 820 NVNSIVKIQAFFRARKAQDDY-------RILVHAPHPPLSVVRRFAHLLNQSQQDFLAEA 872
Query: 3200 KQEKFTSGIIKIQALWRGYSWRKKNDCTKIKAIRLSLQVVNREIREE-----NKLYKRTA 3254
+ K +++ + S ++ I I++ L V NR +E KL KR
Sbjct: 873 ELLKLQEEVVR-----KIRSNQQLEQDLNIMDIKIGLLVKNRITLQEVVSHCKKLTKRNK 927
Query: 3255 LALHYLLT---YKHLSAI-------LEALKHLEVVTRLSPL 3285
L ++ K L ++ LEA +HL + + P+
Sbjct: 928 EQLSDMMVLDKQKGLKSLSKEKRQKLEAYQHLFYLLQTQPI 968
Score = 40.4 bits (93), Expect = 0.031
Identities = 38/143 (26%), Positives = 68/143 (47%), Gaps = 29/143 (20%)
Query: 2821 IQKAFCRMVTRKLETQKCAALRIQFFLQMAVYRRRFVQQKRAAITLQHYFRTWQTRKQFL 2880
IQ A + VT + Q+ + F +Q+ R F+ +++ A H+ RTW
Sbjct: 710 IQSAVTK-VTAAYDRQQLWKANVGFVIQLQARLRGFLVRQKFA-EHSHFLRTWLP----- 762
Query: 2881 LYRKAAVVLQNHYRAFLSAKHQRQVYLQIRS-------SVIIIQARSKGFIQKRK----- 2928
A + +Q H+R + QR++YL+ ++I IQA ++ + +R+
Sbjct: 763 ----AVIKIQAHWRGY----RQRKIYLEWLQYFKANLDAIIKIQAWARMWAARRQYLRRL 814
Query: 2929 --FQEIKNSTIKIQAMWRRYRAK 2949
FQ+ NS +KIQA +R +A+
Sbjct: 815 HYFQKNVNSIVKIQAFFRARKAQ 837
Score = 39.7 bits (91), Expect = 0.053
Identities = 51/246 (20%), Positives = 106/246 (43%), Gaps = 48/246 (19%)
Query: 1630 QKTRSAVIVLQSAYRGMQARKMYIHILTSVIKIQSYYRAYVSKKEFLSLKN-------AT 1682
++ +SAV + +AY Q K + VI++Q+ R ++ +++F + A
Sbjct: 708 EEIQSAVTKVTAAYDRQQLWKANVGF---VIQLQARLRGFLVRQKFAEHSHFLRTWLPAV 764
Query: 1683 IKLQSTVKMKQTRKQYLHLRAAALFIQQCYRSKKIAAQKREEYMQMRESCIKLQAFVRGY 1742
IK+Q+ H R YR +KI + + + ++ IK+QA+ R +
Sbjct: 765 IKIQA------------HWRG--------YRQRKIYLEWLQYFKANLDAIIKIQAWARMW 804
Query: 1743 LVRKQ-------MRLQRKAVISLQSYFRMRKARQYYLKMYKA----IIVIQNYYHAYKAQ 1791
R+Q + +++ +Q++FR RKA+ Y + A + V++ + H
Sbjct: 805 AARRQYLRRLHYFQKNVNSIVKIQAFFRARKAQDDYRILVHAPHPPLSVVRRFAHLLN-- 862
Query: 1792 VNQRKNFLQVKKAATCLQAAYRGYKVRQLIKQQ-SIAALKIQSAFRGYNKRVKYQSVLQS 1850
+++FL + + R + Q ++Q +I +KI + R+ Q V+
Sbjct: 863 -QSQQDFLAEAELLKLQEEVVRKIRSNQQLEQDLNIMDIKIGLLVK---NRITLQEVVSH 918
Query: 1851 IIKIQR 1856
K+ +
Sbjct: 919 CKKLTK 924
Score = 38.1 bits (87), Expect = 0.15
Identities = 45/165 (27%), Positives = 75/165 (45%), Gaps = 25/165 (15%)
Query: 2173 LQASFRGVRVRRT-------LRKMQTAATLIQSNYRRYRQQT-------YFN-KLKKITK 2217
LQA RG VR+ LR A IQ+++R YRQ+ YF L I K
Sbjct: 737 LQARLRGFLVRQKFAEHSHFLRTWLPAVIKIQAHWRGYRQRKIYLEWLQYFKANLDAIIK 796
Query: 2218 T-VQQRYWAMKERNIQFQRY-NKLRHSVIYIQAIFRGKKARRHLKMMHIA---ATLIQRR 2272
R WA + + ++ Y K +S++ IQA FR +KA+ +++ A + RR
Sbjct: 797 IQAWARMWAARRQYLRRLHYFQKNVNSIVKIQAFFRARKAQDDYRILVHAPHPPLSVVRR 856
Query: 2273 FRTLMMRRRFLSLKKTAIL-----IQRKYRAHLCTKHHLQFLQVQ 2312
F L+ + + L + +L + RK R++ + L + ++
Sbjct: 857 FAHLLNQSQQDFLAEAELLKLQEEVVRKIRSNQQLEQDLNIMDIK 901
Score = 37.7 bits (86), Expect = 0.20
Identities = 43/178 (24%), Positives = 84/178 (47%), Gaps = 40/178 (22%)
Query: 1586 IIKFQAHVRKHQQRQKYKKMKKAAVIIQTHFRAYIFAMKVLASYQKTRSAVIVLQSAYRG 1645
+IK QAH R ++QR+ Y ++ L ++ A+I +Q+ R
Sbjct: 764 VIKIQAHWRGYRQRKIY--------------------LEWLQYFKANLDAIIKIQAWARM 803
Query: 1646 MQARKMYIHIL-------TSVIKIQSYYRAYVSKKEFLSLKNATIKLQSTVK-----MKQ 1693
AR+ Y+ L S++KIQ+++RA ++ ++ L +A S V+ + Q
Sbjct: 804 WAARRQYLRRLHYFQKNVNSIVKIQAFFRARKAQDDYRILVHAPHPPLSVVRRFAHLLNQ 863
Query: 1694 TRKQYLHLRAAALFIQQCYRSKKIAAQKREEYMQMRESCIKLQAFVRGYLVRKQMRLQ 1751
+++ +L A L +Q+ K + Q+ E+ + + + IK+ G LV+ ++ LQ
Sbjct: 864 SQQDFL-AEAELLKLQEEVVRKIRSNQQLEQDLNIMD--IKI-----GLLVKNRITLQ 913
Score = 37.4 bits (85), Expect = 0.26
Identities = 67/287 (23%), Positives = 125/287 (43%), Gaps = 45/287 (15%)
Query: 2269 IQRRFRTLMMRRRFLSLKK-------TAILIQRKYRAHLCTKHHLQFLQV----QNAVIK 2317
+Q R R ++R++F I IQ +R + K +L++LQ +A+IK
Sbjct: 737 LQARLRGFLVRQKFAEHSHFLRTWLPAVIKIQAHWRGYRQRKIYLEWLQYFKANLDAIIK 796
Query: 2318 IQSSYRRWMIRKR-MREMH------RAATFIQSTFRMHRLHMRYQALKQA-----SVVIQ 2365
IQ+ R W R++ +R +H + IQ+ FR + Y+ L A SVV +
Sbjct: 797 IQAWARMWAARRQYLRRLHYFQKNVNSIVKIQAFFRARKAQDDYRILVHAPHPPLSVVRR 856
Query: 2366 QQYQANRAAKLQRQHYLRQRHSAVILQAAFRGMKTRRHLKSMHSSATLIQSRFRSLLVRR 2425
+ N++ +Q +L + + + R +++ + L+ ++ + LLV+
Sbjct: 857 FAHLLNQS----QQDFLAEAELLKLQEEVVRKIRSNQQLE---QDLNIMDIKI-GLLVKN 908
Query: 2426 RFISLKKATIFVQRKYRATICAKHKLYQFLHLRKAAITIQSSYRRLMVKK--KLQEMQRA 2483
R I+L++ V + T K +L + L K Q + L +K KL+ Q
Sbjct: 909 R-ITLQEV---VSHCKKLTKRNKEQLSDMMVLDK-----QKGLKSLSKEKRQKLEAYQHL 959
Query: 2484 AVLIQATFRMYRTYITFQTWKHASILIQQH--YRTYRAAKLQRENYI 2528
L+Q T +Y + FQ ++ + + + Y A +RE Y+
Sbjct: 960 FYLLQ-TQPIYLAKLIFQMPQNKTTKFMEAVIFSLYNYASSRREAYL 1005
Score = 36.6 bits (83), Expect = 0.45
Identities = 37/157 (23%), Positives = 64/157 (40%), Gaps = 40/157 (25%)
Query: 1344 EKVQNKAASLIQGYWRRYSTRQRFLKLKYYSII-LQSRIRMIIAVTSY-------KRYLW 1395
E++Q+ + Y RQ+ K +I LQ+R+R + + + +L
Sbjct: 708 EEIQSAVTKVTAAY-----DRQQLWKANVGFVIQLQARLRGFLVRQKFAEHSHFLRTWLP 762
Query: 1396 ATVTIQRHWRAYLRRKQDQQRYEMLKSSTLIIQSMFRKWKQRKMQSQVKATVILQRAFRE 1455
A + IQ HWR Y +RK ++ +W Q ++ + A + +Q R
Sbjct: 763 AVIKIQAHWRGYRQRK------------------IYLEWLQ-YFKANLDAIIKIQAWARM 803
Query: 1456 WHLRKQ--------AKEENSAIIIQSWYRMHKELRKY 1484
W R+Q K NS + IQ+++R K Y
Sbjct: 804 WAARRQYLRRLHYFQKNVNSIVKIQAFFRARKAQDDY 840
Score = 33.9 bits (76), Expect = 2.9
Identities = 35/158 (22%), Positives = 73/158 (46%), Gaps = 28/158 (17%)
Query: 2627 AAIIIQKHCKAFKIRKHYLHLRATVVSIQRRYRKLTAVRTQAVICIQSYYRGFKVRKD-I 2685
A I IQ H + ++ RK YL + + A+I IQ++ R + R+ +
Sbjct: 763 AVIKIQAHWRGYRQRKIYL-----------EWLQYFKANLDAIIKIQAWARMWAARRQYL 811
Query: 2686 QNMH------RAATLIQSFYRMHRAKVDYETKKTA----IVVIQNYYRLYVRVKTERKNF 2735
+ +H + IQ+F+R +A+ DY A + V++ + L + +++F
Sbjct: 812 RRLHYFQKNVNSIVKIQAFFRARKAQDDYRILVHAPHPPLSVVRRFAHL---LNQSQQDF 868
Query: 2736 LAVQKSVRTIQAAFRGMKVRQKLK---NVSEEKMAAIV 2770
LA + ++ + R ++ Q+L+ N+ + K+ +V
Sbjct: 869 LAEAELLKLQEEVVRKIRSNQQLEQDLNIMDIKIGLLV 906
Score = 32.3 bits (72), Expect = 8.4
Identities = 36/147 (24%), Positives = 68/147 (46%), Gaps = 30/147 (20%)
Query: 1377 LQSRIRMIIAVTSYKRYLWAT-----VTIQRHWRAYLRRKQDQQRYEMLKS---STLIIQ 1428
+QS + + A ++ LW + +Q R +L R++ + L++ + + IQ
Sbjct: 710 IQSAVTKVTAAYD-RQQLWKANVGFVIQLQARLRGFLVRQKFAEHSHFLRTWLPAVIKIQ 768
Query: 1429 SMFRKWKQRKMQSQVKATVILQRAFREWHLRKQAKEENSAIIIQSWYRMHKELRKYI--- 1485
+ +R ++QRK+ + EW L+ ++ I IQ+W RM R+Y+
Sbjct: 769 AHWRGYRQRKI-------------YLEW-LQYFKANLDAIIKIQAWARMWAARRQYLRRL 814
Query: 1486 -YIR---SCVVIIQKRFRCFQAQKLYK 1508
Y + + +V IQ FR +AQ Y+
Sbjct: 815 HYFQKNVNSIVKIQAFFRARKAQDDYR 841
>gi|115430237 spectrin, beta, non-erythrocytic 4 isoform sigma1 [Homo
sapiens]
Length = 2564
Score = 54.3 bits (129), Expect = 2e-06
Identities = 53/198 (26%), Positives = 80/198 (40%), Gaps = 48/198 (24%)
Query: 965 VTNLAVDLQCGVRLVRTMELLTQNWDLSKKLRIPAISRLQKMHNVDIVLQVLKSRGIELS 1024
+ +L VDL+ G L R +E+L+ L + R R+ + NVD LQ LK + + L
Sbjct: 82 IGDLYVDLRDGFVLTRLLEVLSGE-QLPRPTR--GRMRIHSLENVDKALQFLKEQRVHLE 138
Query: 1025 DEHGNTILSKDIVDRHREKTLRLLWKIAFAFQVDISLNLDQLKEEIAFLKHTKSIKKTIS 1084
+ + S DIVD + TL L+W I FQ+ + +K E + T+S K +
Sbjct: 139 N-----VGSHDIVDGNHRLTLGLVWTIILRFQIQV------IKIETEDNRETRSAKDALL 187
Query: 1085 LLSCHSDDLINKKKGKRDSGSFEQYSENIKLLMDWVNAVCAFYNK-KVENFTVSFSDGRV 1143
L W A Y + ++NFT S+ DG
Sbjct: 188 L---------------------------------WCQMKTAGYPEVNIQNFTTSWRDGLA 214
Query: 1144 LCYLIHHYHPCYVPFDAI 1161
LIH + P V F +
Sbjct: 215 FNALIHRHRPDLVDFSKL 232
>gi|5902122 spectrin, beta, non-erythrocytic 2 [Homo sapiens]
Length = 2390
Score = 52.8 bits (125), Expect = 6e-06
Identities = 55/199 (27%), Positives = 84/199 (42%), Gaps = 50/199 (25%)
Query: 965 VTNLAVDLQCGVRLVRTMELLTQNWDLSKKLRIPAISRLQKMHNVDIVLQVLKSRGIELS 1024
V +L DL+ G L+R +E+L+ L K + R+ + NVD LQ LK + + L
Sbjct: 78 VGDLYSDLRDGRNLLRLLEVLSGEI-LPKPTK--GRMRIHCLENVDKALQFLKEQKVHLE 134
Query: 1025 DEHGNTILSKDIVDRHREKTLRLLWKIAFAFQV-DISLNLDQLKEEIAFLKHTKSIKKTI 1083
+ + S DIVD + TL L+W I FQ+ DIS+ + KE
Sbjct: 135 N-----MGSHDIVDGNHRLTLGLVWTIILRFQIQDISVETEDNKE--------------- 174
Query: 1084 SLLSCHSDDLINKKKGKRDSGSFEQYSENIKLLMDWVNAVCAFY-NKKVENFTVSFSDGR 1142
KK +D+ L+ W A Y N V NFT S+ DG
Sbjct: 175 -------------KKSAKDA------------LLLWCQMKTAGYPNVNVHNFTTSWRDGL 209
Query: 1143 VLCYLIHHYHPCYVPFDAI 1161
++H + P + F+++
Sbjct: 210 AFNAIVHKHRPDLLDFESL 228
>gi|224451032 KIAA1683 isoform a [Homo sapiens]
Length = 1367
Score = 52.4 bits (124), Expect = 8e-06
Identities = 53/242 (21%), Positives = 102/242 (42%), Gaps = 25/242 (10%)
Query: 1608 AAVIIQTHFRAYIFAMKVLASYQKTRSAVIVLQSAYRGMQARKMYIHILTSVIKIQSYYR 1667
A + IQ R Y+ ++ ++ +V+Q+ +RG + R+ H+ + IQS +R
Sbjct: 1116 AVITIQAGVRGYLARRRIRLWHR----GAMVIQATWRGYRVRRNLAHLCRATTTIQSAWR 1171
Query: 1668 AYVSKKE----FLSLKNAT-IKLQSTVKMKQTRKQYLHLRAAALFIQQCYRSKKIAAQKR 1722
Y ++++ + L T ++L S + R + RA + +C++S + A
Sbjct: 1172 GYSTRRDQARHWQMLHPVTWVELGSRAGVMSDRSWFQDGRARTVSDHRCFQSCQAHACSV 1231
Query: 1723 EEYMQMRESCIKLQAFVRGYLVRKQM---RLQRKAVISLQSYFRMRKARQYYLKMYKAII 1779
+ R + G R R Q V+ + Y+
Sbjct: 1232 CHSLSSRIGSPPSVVMLVGSSPRTCHTCGRTQPTRVVQGMGQGTEGPGAVSWASAYQLAA 1291
Query: 1780 VIQNYYHAYKAQVNQRKNFLQVKKAATCLQAAYRGYKVRQLIKQQSIAALKIQSAFRGYN 1839
+ H + KAAT +Q+A+RG+K+RQ ++QQ +AA +Q+ +RG++
Sbjct: 1292 LSPRQPH-------------RQDKAATAIQSAWRGFKIRQQMRQQQMAAKIVQATWRGHH 1338
Query: 1840 KR 1841
R
Sbjct: 1339 TR 1340
Score = 50.1 bits (118), Expect = 4e-05
Identities = 53/236 (22%), Positives = 97/236 (41%), Gaps = 32/236 (13%)
Query: 2355 QALKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAFRGMKTRRHLKSMHSSATLI 2414
QA ++ ++ QA L R+ A+++QA +RG + RR+L + + T I
Sbjct: 1107 QAAEEIRILAVITIQAGVRGYLARRRIRLWHRGAMVIQATWRGYRVRRNLAHLCRATTTI 1166
Query: 2415 QSRFRSLLVRR------------RFISL-KKATIFVQRKY----RATICAKHKLYQFLHL 2457
QS +R RR ++ L +A + R + RA + H+ +Q
Sbjct: 1167 QSAWRGYSTRRDQARHWQMLHPVTWVELGSRAGVMSDRSWFQDGRARTVSDHRCFQSCQA 1226
Query: 2458 RKAAITIQSSYRRLMVKKKLQEMQRAAVLIQATFRMYRTYITFQTWKHASILIQ------ 2511
++ S R + +L+ ++ R T Q + + Q
Sbjct: 1227 HACSVCHSLSSR-------IGSPPSVVMLVGSSPRTCHTCGRTQPTRVVQGMGQGTEGPG 1279
Query: 2512 --QHYRTYRAAKLQRENYIRQWHSAVVIQAAYKGMKARQLLREKHKASIVIQSTYR 2565
Y+ A L RQ +A IQ+A++G K RQ +R++ A+ ++Q+T+R
Sbjct: 1280 AVSWASAYQLAALSPRQPHRQDKAATAIQSAWRGFKIRQQMRQQQMAAKIVQATWR 1335
Score = 46.2 bits (108), Expect = 6e-04
Identities = 49/224 (21%), Positives = 86/224 (38%), Gaps = 45/224 (20%)
Query: 1804 AATCLQAAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRVKYQSVLQSIIKIQRWYRAYKT 1863
A +QA RGY R+ I+ A+ IQ+ +RGY R + ++ IQ +R Y T
Sbjct: 1116 AVITIQAGVRGYLARRRIRLWHRGAMVIQATWRGYRVRRNLAHLCRATTTIQSAWRGYST 1175
Query: 1864 LHDTRTHF----------LKTKAAVISLQSAYRGWKVRKQIRREHQAALKIQSAFRMAKA 1913
D H+ L ++A V+S +S ++ + R +H+ Q+
Sbjct: 1176 RRDQARHWQMLHPVTWVELGSRAGVMSDRSWFQDGRARTV--SDHRCFQSCQAHACSVCH 1233
Query: 1914 QKQFRLFKTAALVI---QQNFRAWTAGRKQCMEYIE------------------------ 1946
R+ ++V+ T GR Q ++
Sbjct: 1234 SLSSRIGSPPSVVMLVGSSPRTCHTCGRTQPTRVVQGMGQGTEGPGAVSWASAYQLAALS 1293
Query: 1947 ------LRHAVLVLQSMWKGKTLRRQLQRQHKCAIIIQSYYRMH 1984
A +QS W+G +R+Q+++Q A I+Q+ +R H
Sbjct: 1294 PRQPHRQDKAATAIQSAWRGFKIRQQMRQQQMAAKIVQATWRGH 1337
Score = 45.8 bits (107), Expect = 7e-04
Identities = 68/289 (23%), Positives = 113/289 (39%), Gaps = 60/289 (20%)
Query: 2134 ISYHTMRKAAIVIQVRCRAYYQGKMQREKYLTILKAVKVLQASFRGVRVRRTLRKMQTAA 2193
+S + I+ + +A +G + R + + V+QA++RG RVRR L + A
Sbjct: 1104 VSMQAAEEIRILAVITIQAGVRGYLARRRIRLWHRGAMVIQATWRGYRVRRNLAHLCRAT 1163
Query: 2194 TLIQSNYRRYRQQTYFNKLKKITKTVQQRYWAMKERNIQFQRYNKLRHSVIYIQAIFRGK 2253
T IQS +R Y T+ Q R+W M H V +++ G
Sbjct: 1164 TTIQSAWRGYS-----------TRRDQARHWQM-------------LHPVTWVEL---GS 1196
Query: 2254 KARRHLKMMHIAATLIQRRFRTLMMRRRFLSLKKTAILIQRKYRAHLCTKHHLQFLQV-- 2311
+A +M + R RT+ R F S +AH C+ H ++
Sbjct: 1197 RA----GVMSDRSWFQDGRARTVSDHRCFQSC-----------QAHACSVCHSLSSRIGS 1241
Query: 2312 -QNAVIKIQSSYRRWMIRKRMREMHRAATFIQSTFRMHRLHMRYQALKQASVVIQQQYQA 2370
+ V+ + SS R R + Q T +V YQ
Sbjct: 1242 PPSVVMLVGSSPRTCHTCGRTQPTRVVQGMGQGT------------EGPGAVSWASAYQL 1289
Query: 2371 NRAAKLQRQHYLRQRHSAVILQAAFRGMKTRRHLKSMHSSATLIQSRFR 2419
AA RQ + RQ +A +Q+A+RG K R+ ++ +A ++Q+ +R
Sbjct: 1290 --AALSPRQPH-RQDKAATAIQSAWRGFKIRQQMRQQQMAAKIVQATWR 1335
Score = 42.7 bits (99), Expect = 0.006
Identities = 45/225 (20%), Positives = 92/225 (40%), Gaps = 41/225 (18%)
Query: 1950 AVLVLQSMWKGKTLRRQLQRQHKCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYRAYSI 2009
AV+ +Q+ +G RR+++ H+ A++IQ+ +R + ++ + +A IQ +R YS
Sbjct: 1116 AVITIQAGVRGYLARRRIRLWHRGAMVIQATWRGYRVRRNLAHLCRATTTIQSAWRGYST 1175
Query: 2010 GREQ----------NHLYLKTKAAVVTLQSAYRGMKVR---------------------- 2037
R+Q + L ++A V++ +S ++ + R
Sbjct: 1176 RRDQARHWQMLHPVTWVELGSRAGVMSDRSWFQDGRARTVSDHRCFQSCQAHACSVCHSL 1235
Query: 2038 -KRIKDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQ--------RWYRGIKITNHQHK 2088
RI + + S R T + R + Q W ++ +
Sbjct: 1236 SSRIGSPPSVVMLVGSSPRTCHTCGRTQPTRVVQGMGQGTEGPGAVSWASAYQLAALSPR 1295
Query: 2089 EYLNLKKTAIKIQSVYRGIRVRRHIQHMHRAATFIKAMFKMHQSR 2133
+ K A IQS +RG ++R+ ++ AA ++A ++ H +R
Sbjct: 1296 QPHRQDKAATAIQSAWRGFKIRQQMRQQQMAAKIVQATWRGHHTR 1340
Score = 42.7 bits (99), Expect = 0.006
Identities = 60/260 (23%), Positives = 105/260 (40%), Gaps = 41/260 (15%)
Query: 2242 SVIYIQAIFRGKKARRHLKMMHIAATLIQRRFRTLMMRRRFLSLKKTAILIQRKYRAHLC 2301
+VI IQA RG ARR +++ H A +IQ +R +RR AHLC
Sbjct: 1116 AVITIQAGVRGYLARRRIRLWHRGAMVIQATWRGYRVRRNL---------------AHLC 1160
Query: 2302 TKHHLQFLQVQNAVIKIQSSYRRWMIRK---RMREMHRAATFIQSTFRMHRLHMR--YQA 2356
A IQS++R + R+ R +M T+++ R + R +Q
Sbjct: 1161 -----------RATTTIQSAWRGYSTRRDQARHWQMLHPVTWVELGSRAGVMSDRSWFQD 1209
Query: 2357 LKQASVVIQQQYQANRAAKLQRQHYLRQRHSAVILQAAFRGMKTRRHLKSMHSSATLIQS 2416
+ +V + +Q+ +A H L R + G R + T +
Sbjct: 1210 GRARTVSDHRCFQSCQAHACSVCHSLSSRIGSPPSVVMLVGSSPRTCHTCGRTQPTRVVQ 1269
Query: 2417 RFRSLLVRRRFISLKKATIFVQRKYRATICAKHKLYQFLHLRKAAITIQSSYRRLMVKKK 2476
+S A Y+ + + ++ KAA IQS++R ++++
Sbjct: 1270 GMGQGTEGPGAVSWASA-------YQLAALSPRQPHR---QDKAATAIQSAWRGFKIRQQ 1319
Query: 2477 LQEMQRAAVLIQATFRMYRT 2496
+++ Q AA ++QAT+R + T
Sbjct: 1320 MRQQQMAAKIVQATWRGHHT 1339
Score = 41.2 bits (95), Expect = 0.018
Identities = 52/245 (21%), Positives = 97/245 (39%), Gaps = 29/245 (11%)
Query: 1826 IAALKIQSAFRGYNKRVKYQSVLQSIIKIQRWYRAYKTLHDTRTHFLKTKAAVISLQSAY 1885
+A + IQ+ RGY R + + + + IQ +R Y+ R + A ++QSA+
Sbjct: 1115 LAVITIQAGVRGYLARRRIRLWHRGAMVIQATWRGYR----VRRNLAHLCRATTTIQSAW 1170
Query: 1886 RGWKVRKQIRREHQAA-----LKIQSAFRMAKAQKQFRLFKTAALVIQQNFRAWTAGRKQ 1940
RG+ R+ R Q +++ S + + F Q+ RA T +
Sbjct: 1171 RGYSTRRDQARHWQMLHPVTWVELGSRAGVMSDRSWF-----------QDGRARTVSDHR 1219
Query: 1941 CMEYIELRHAVLVLQSMWK-----GKTLRRQLQRQHKCAIIIQSYYRMHVQQKKWKIMKK 1995
C + + HA V S+ + C ++ VQ
Sbjct: 1220 CFQSCQ-AHACSVCHSLSSRIGSPPSVVMLVGSSPRTCHTCGRTQPTRVVQGMGQGTEGP 1278
Query: 1996 AALLIQKYYRAYSIGREQNHLYLKTKAAVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYR 2055
A+ Y+ ++ Q H + A +QSA+RG K+R++++ AA +Q+ +R
Sbjct: 1279 GAVSWASAYQLAALSPRQPH---RQDKAATAIQSAWRGFKIRQQMRQQQMAAKIVQATWR 1335
Query: 2056 AYKTK 2060
+ T+
Sbjct: 1336 GHHTR 1340
Score = 40.8 bits (94), Expect = 0.024
Identities = 20/39 (51%), Positives = 28/39 (71%)
Query: 1803 KAATCLQAAYRGYKVRQLIKQQSIAALKIQSAFRGYNKR 1841
+AAT +QA +RGY +RQ + Q +AA IQ A+R +NKR
Sbjct: 105 RAATLIQANWRGYWLRQKLISQMMAAKAIQEAWRRFNKR 143
Score = 40.4 bits (93), Expect = 0.031
Identities = 50/218 (22%), Positives = 86/218 (39%), Gaps = 38/218 (17%)
Query: 2664 VRTQAVICIQSYYRGFKVRKDIQNMHRAATLIQSFYRMHRAKVDYETKKTAIVVIQNYYR 2723
+R AVI IQ+ RG+ R+ I+ HR A +IQ+ +R +R + + A IQ+ +R
Sbjct: 1112 IRILAVITIQAGVRGYLARRRIRLWHRGAMVIQATWRGYRVRRNLAHLCRATTTIQSAWR 1171
Query: 2724 LYVRVKTERKNF----------LAVQKSVRTIQAAFRGMKVRQ----------------- 2756
Y + + +++ L + V + ++ F+ + R
Sbjct: 1172 GYSTRRDQARHWQMLHPVTWVELGSRAGVMSDRSWFQDGRARTVSDHRCFQSCQAHACSV 1231
Query: 2757 ----KLKNVSEEKMAAIVNQSALCCYR-SKTQYEAV------QSEGVMIQEWYKASGLAC 2805
+ S + +V S C+ +TQ V +EG W A LA
Sbjct: 1232 CHSLSSRIGSPPSVVMLVGSSPRTCHTCGRTQPTRVVQGMGQGTEGPGAVSWASAYQLAA 1291
Query: 2806 SQEAEYHSQSRAAVTIQKAFCRMVTRKLETQKCAALRI 2843
+ H Q +AA IQ A+ R+ Q+ A +I
Sbjct: 1292 LSPRQPHRQDKAATAIQSAWRGFKIRQQMRQQQMAAKI 1329
Score = 39.7 bits (91), Expect = 0.053
Identities = 25/67 (37%), Positives = 34/67 (50%), Gaps = 9/67 (13%)
Query: 1299 IQLAVINFLAKQRLRKRVNAALVIQKYWRRVLAQRKLLMLKKEKLEKVQNKAASLIQGYW 1358
IQ V +LA++R+R A+VIQ WR +R L L +A + IQ W
Sbjct: 1120 IQAGVRGYLARRRIRLWHRGAMVIQATWRGYRVRRNLAHL---------CRATTTIQSAW 1170
Query: 1359 RRYSTRQ 1365
R YSTR+
Sbjct: 1171 RGYSTRR 1177
Score = 38.5 bits (88), Expect = 0.12
Identities = 22/67 (32%), Positives = 36/67 (53%)
Query: 2533 SAVVIQAAYKGMKARQLLREKHKASIVIQSTYRMYRQYCFYQKLQWATKIIQEKYRANKK 2592
+ + IQA +G AR+ +R H+ ++VIQ+T+R YR L AT IQ +R
Sbjct: 1116 AVITIQAGVRGYLARRRIRLWHRGAMVIQATWRGYRVRRNLAHLCRATTTIQSAWRGYST 1175
Query: 2593 KQKVFQH 2599
++ +H
Sbjct: 1176 RRDQARH 1182
Score = 37.4 bits (85), Expect = 0.26
Identities = 17/61 (27%), Positives = 35/61 (57%)
Query: 2608 VQAGFQDMNIKKQIQEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQRRYRKLTAVRTQ 2667
+QAG + +++I+ H+ A++IQ + +++R++ HL +IQ +R + R Q
Sbjct: 1120 IQAGVRGYLARRRIRLWHRGAMVIQATWRGYRVRRNLAHLCRATTTIQSAWRGYSTRRDQ 1179
Query: 2668 A 2668
A
Sbjct: 1180 A 1180
Score = 36.6 bits (83), Expect = 0.45
Identities = 19/63 (30%), Positives = 36/63 (57%), Gaps = 1/63 (1%)
Query: 2912 SVIIIQARSKGFIQKRKFQEIKNSTIKIQAMWRRYRAKKYLCKV-KAACKIQAWYRCWRA 2970
+VI IQA +G++ +R+ + + IQA WR YR ++ L + +A IQ+ +R +
Sbjct: 1116 AVITIQAGVRGYLARRRIRLWHRGAMVIQATWRGYRVRRNLAHLCRATTTIQSAWRGYST 1175
Query: 2971 HKE 2973
++
Sbjct: 1176 RRD 1178
Score = 35.4 bits (80), Expect = 0.99
Identities = 23/90 (25%), Positives = 40/90 (44%)
Query: 1337 MLKKEKLEKVQNKAASLIQGYWRRYSTRQRFLKLKYYSIILQSRIRMIIAVTSYKRYLWA 1396
M+ + E+++ A IQ R Y R+R ++++Q+ R + A
Sbjct: 1103 MVSMQAAEEIRILAVITIQAGVRGYLARRRIRLWHRGAMVIQATWRGYRVRRNLAHLCRA 1162
Query: 1397 TVTIQRHWRAYLRRKQDQQRYEMLKSSTLI 1426
T TIQ WR Y R+ + ++ML T +
Sbjct: 1163 TTTIQSAWRGYSTRRDQARHWQMLHPVTWV 1192
Score = 35.0 bits (79), Expect = 1.3
Identities = 27/94 (28%), Positives = 46/94 (48%), Gaps = 4/94 (4%)
Query: 2534 AVVIQAAYKGMKARQLLREKHKASIVIQSTYRMY--RQYCFYQKLQWATKIIQEKYRANK 2591
AVV A+K + ++ +A+ +IQ+ +R Y RQ Q + A K IQE +R
Sbjct: 84 AVVESQAFKNILVDEMDMMHARAATLIQANWRGYWLRQKLISQMM--AAKAIQEAWRRFN 141
Query: 2592 KKQKVFQHNELKKETCVQAGFQDMNIKKQIQEQH 2625
K+ + L K+T + G + +Q++ QH
Sbjct: 142 KRHILHSSKSLVKKTRAEEGDIPYHAPQQVRFQH 175
Score = 35.0 bits (79), Expect = 1.3
Identities = 14/39 (35%), Positives = 25/39 (64%)
Query: 2667 QAVICIQSYYRGFKVRKDIQNMHRAATLIQSFYRMHRAK 2705
+A IQS +RGFK+R+ ++ AA ++Q+ +R H +
Sbjct: 1302 KAATAIQSAWRGFKIRQQMRQQQMAAKIVQATWRGHHTR 1340
Score = 33.9 bits (76), Expect = 2.9
Identities = 37/138 (26%), Positives = 61/138 (44%), Gaps = 5/138 (3%)
Query: 2051 QSKYRAYKTKKKYA---TYRASAIIIQRWYRGIKITNHQHKEYLNLKKTAIKIQSVYRGI 2107
QS RA++ + A T+R A++ R G + + Q E + + I IQ+ RG
Sbjct: 1070 QSWNRAWEPARGAASWDTWRNKAVVPPR-RSGEPMVSMQAAEEIRIL-AVITIQAGVRGY 1127
Query: 2108 RVRRHIQHMHRAATFIKAMFKMHQSRISYHTMRKAAIVIQVRCRAYYQGKMQREKYLTIL 2167
RR I+ HR A I+A ++ ++ R + + +A IQ R Y + Q + +
Sbjct: 1128 LARRRIRLWHRGAMVIQATWRGYRVRRNLAHLCRATTTIQSAWRGYSTRRDQARHWQMLH 1187
Query: 2168 KAVKVLQASFRGVRVRRT 2185
V S GV R+
Sbjct: 1188 PVTWVELGSRAGVMSDRS 1205
Score = 32.7 bits (73), Expect = 6.4
Identities = 20/77 (25%), Positives = 37/77 (48%), Gaps = 5/77 (6%)
Query: 2168 KAVKVLQASFRGVRVRRTLRKMQTAATLIQSNYRRYRQQTYFNKLKKITKTVQQR----- 2222
+A ++QA++RG +R+ L AA IQ +RR+ ++ + K + K +
Sbjct: 105 RAATLIQANWRGYWLRQKLISQMMAAKAIQEAWRRFNKRHILHSSKSLVKKTRAEEGDIP 164
Query: 2223 YWAMKERNIQFQRYNKL 2239
Y A ++ Q N+L
Sbjct: 165 YHAPQQVRFQHPEENRL 181
Score = 32.7 bits (73), Expect = 6.4
Identities = 16/39 (41%), Positives = 22/39 (56%)
Query: 3184 AASVIQKAVRHFLLRKKQEKFTSGIIKIQALWRGYSWRK 3222
A IQ VR +L R++ + G + IQA WRGY R+
Sbjct: 1116 AVITIQAGVRGYLARRRIRLWHRGAMVIQATWRGYRVRR 1154
Score = 32.3 bits (72), Expect = 8.4
Identities = 19/65 (29%), Positives = 33/65 (50%), Gaps = 4/65 (6%)
Query: 1586 IIKFQAHVRKHQQRQKYKKMKKAAVIIQTHFRAYIFAMKVLASYQKTRSAVIVLQSAYRG 1645
+I QA VR + R++ + + A++IQ +R Y +V + A +QSA+RG
Sbjct: 1117 VITIQAGVRGYLARRRIRLWHRGAMVIQATWRGY----RVRRNLAHLCRATTTIQSAWRG 1172
Query: 1646 MQARK 1650
R+
Sbjct: 1173 YSTRR 1177
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.133 0.385
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 111,167,076
Number of Sequences: 37866
Number of extensions: 4502754
Number of successful extensions: 23076
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 65
Number of HSP's successfully gapped in prelim test: 108
Number of HSP's that attempted gapping in prelim test: 18412
Number of HSP's gapped (non-prelim): 2347
length of query: 3477
length of database: 18,247,518
effective HSP length: 121
effective length of query: 3356
effective length of database: 13,665,732
effective search space: 45862196592
effective search space used: 45862196592
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 72 (32.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.