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Search of human proteins with 12597625
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|12597625 activating transcription factor 5 [Homo sapiens]
(282 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|12597625 activating transcription factor 5 [Homo sapiens] 583 e-167
gi|33469974 activating transcription factor 4 [Homo sapiens] 94 2e-19
gi|33469976 activating transcription factor 4 [Homo sapiens] 94 2e-19
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 70 2e-12
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 68 8e-12
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 67 1e-11
gi|47132519 Ras association and pleckstrin homology domains 1 is... 65 5e-11
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 65 7e-11
gi|153792074 proline rich 12 [Homo sapiens] 64 1e-10
gi|194294554 SET binding protein 1 isoform a [Homo sapiens] 64 2e-10
gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom... 63 3e-10
gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom... 63 3e-10
gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap... 63 3e-10
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 63 3e-10
gi|126090663 zinc finger homeodomain 4 [Homo sapiens] 62 4e-10
gi|157168329 formin 1 [Homo sapiens] 62 6e-10
gi|33356148 formin-like 1 [Homo sapiens] 62 7e-10
gi|60460889 Myb protein P42POP [Homo sapiens] 61 1e-09
gi|160707881 formin 2 [Homo sapiens] 60 2e-09
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 60 2e-09
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 60 2e-09
gi|52485606 formin-like 2 [Homo sapiens] 60 3e-09
gi|56549694 enabled homolog isoform a [Homo sapiens] 59 5e-09
gi|39930375 enabled homolog isoform b [Homo sapiens] 59 5e-09
gi|115387123 protocadherin 15 isoform CD1-4 precursor [Homo sapi... 59 5e-09
gi|218505798 protocadherin 15 isoform CD1-10 precursor [Homo sap... 59 5e-09
gi|218505785 protocadherin 15 isoform CD1-9 precursor [Homo sapi... 59 5e-09
gi|218505783 protocadherin 15 isoform CD1-8 precursor [Homo sapi... 59 5e-09
gi|218505781 protocadherin 15 isoform CD1-7 precursor [Homo sapi... 59 5e-09
gi|218505779 protocadherin 15 isoform CD1-6 precursor [Homo sapi... 59 5e-09
>gi|12597625 activating transcription factor 5 [Homo sapiens]
Length = 282
Score = 583 bits (1503), Expect = e-167
Identities = 282/282 (100%), Positives = 282/282 (100%)
Query: 1 MSLLATLGLELDRALLPASGLGWLVDYGKLPPAPAPLAPYEVLGGALEGGLPVGGEPLAG 60
MSLLATLGLELDRALLPASGLGWLVDYGKLPPAPAPLAPYEVLGGALEGGLPVGGEPLAG
Sbjct: 1 MSLLATLGLELDRALLPASGLGWLVDYGKLPPAPAPLAPYEVLGGALEGGLPVGGEPLAG 60
Query: 61 DGFSDWMTERVDFTALLPLEPPLPPGTLPQPSPTPPDLEAMASLLKKELEQMEDFFLDAP 120
DGFSDWMTERVDFTALLPLEPPLPPGTLPQPSPTPPDLEAMASLLKKELEQMEDFFLDAP
Sbjct: 61 DGFSDWMTERVDFTALLPLEPPLPPGTLPQPSPTPPDLEAMASLLKKELEQMEDFFLDAP 120
Query: 121 PLPPPSPPPLPPPPLPPAPSLPLSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPPL 180
PLPPPSPPPLPPPPLPPAPSLPLSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPPL
Sbjct: 121 PLPPPSPPPLPPPPLPPAPSLPLSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPPL 180
Query: 181 PPPQQPPPPSPPQPSRLAPYPHPATTRGDRKQKKRDQNKSAALRYRQRKRAEGEALEGEC 240
PPPQQPPPPSPPQPSRLAPYPHPATTRGDRKQKKRDQNKSAALRYRQRKRAEGEALEGEC
Sbjct: 181 PPPQQPPPPSPPQPSRLAPYPHPATTRGDRKQKKRDQNKSAALRYRQRKRAEGEALEGEC 240
Query: 241 QGLEARNRELKERAESVEREIQYVKDLLIEVYKARSQRTRSC 282
QGLEARNRELKERAESVEREIQYVKDLLIEVYKARSQRTRSC
Sbjct: 241 QGLEARNRELKERAESVEREIQYVKDLLIEVYKARSQRTRSC 282
>gi|33469974 activating transcription factor 4 [Homo sapiens]
Length = 351
Score = 93.6 bits (231), Expect = 2e-19
Identities = 51/97 (52%), Positives = 67/97 (69%), Gaps = 8/97 (8%)
Query: 185 QPPPPSPPQPSRLAPYPHPATTRG---DRKQKKRDQNKSAALRYRQRKRAEGEALEGECQ 241
+P P PP +A A +G D+K KK +QNK+AA RYRQ+KRAE EAL GEC+
Sbjct: 257 RPKPYDPPGEKMVA-----AKVKGEKLDKKLKKMEQNKTAATRYRQKKRAEQEALTGECK 311
Query: 242 GLEARNRELKERAESVEREIQYVKDLLIEVYKARSQR 278
LE +N LKERA+S+ +EIQY+KDL+ EV KAR ++
Sbjct: 312 ELEKKNEALKERADSLAKEIQYLKDLIEEVRKARGKK 348
>gi|33469976 activating transcription factor 4 [Homo sapiens]
Length = 351
Score = 93.6 bits (231), Expect = 2e-19
Identities = 51/97 (52%), Positives = 67/97 (69%), Gaps = 8/97 (8%)
Query: 185 QPPPPSPPQPSRLAPYPHPATTRG---DRKQKKRDQNKSAALRYRQRKRAEGEALEGECQ 241
+P P PP +A A +G D+K KK +QNK+AA RYRQ+KRAE EAL GEC+
Sbjct: 257 RPKPYDPPGEKMVA-----AKVKGEKLDKKLKKMEQNKTAATRYRQKKRAEQEALTGECK 311
Query: 242 GLEARNRELKERAESVEREIQYVKDLLIEVYKARSQR 278
LE +N LKERA+S+ +EIQY+KDL+ EV KAR ++
Sbjct: 312 ELEKKNEALKERADSLAKEIQYLKDLIEEVRKARGKK 348
>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
sapiens]
Length = 505
Score = 70.1 bits (170), Expect = 2e-12
Identities = 59/190 (31%), Positives = 75/190 (39%), Gaps = 48/190 (25%)
Query: 78 PLEPPLPP---GTLPQPS-----PTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPPP 129
P PP PP G P P+ P PP A + APP PPPS P
Sbjct: 287 PPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTA---------------APPPPPPSRPS 331
Query: 130 L---PPPPL----PPAPSLPLSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPPLPP 182
+ PPPP PP P+LP S PS P PP + + +A PP PP
Sbjct: 332 VAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVA--------------PPPPP 377
Query: 183 PQQPPPPSPPQPSRLAPYPHPATTRGDRKQKKRDQNKSAALRYRQRKRAEGEALEGECQG 242
P PPP PP P + H T K DQ + A Q K+ E + C G
Sbjct: 378 PPPPPPGPPPPPGLPSDGDHQVPTTAGNKAALLDQIREGA----QLKKVEQNSRPVSCSG 433
Query: 243 LEARNRELKE 252
+A ++++
Sbjct: 434 RDALLDQIRQ 443
Score = 43.9 bits (102), Expect = 2e-04
Identities = 24/68 (35%), Positives = 28/68 (41%), Gaps = 18/68 (26%)
Query: 76 LLPLEPPLPPGTLPQ-PSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPPPLPPPP 134
+ P PP P + P P P PP + + P PPP PPP PPP
Sbjct: 342 MYPPPPPALPSSAPSGPPPPPPSVLGVG-----------------PVAPPPPPPPPPPPG 384
Query: 135 LPPAPSLP 142
PP P LP
Sbjct: 385 PPPPPGLP 392
Score = 37.7 bits (86), Expect = 0.011
Identities = 16/31 (51%), Positives = 17/31 (54%)
Query: 178 PPLPPPQQPPPPSPPQPSRLAPYPHPATTRG 208
PP PP + PPP PP P P P PA RG
Sbjct: 278 PPPPPSRGGPPPPPPPPHNSGPPPPPARGRG 308
Score = 30.4 bits (67), Expect = 1.8
Identities = 17/33 (51%), Positives = 18/33 (54%), Gaps = 6/33 (18%)
Query: 176 GMPPLPPPQQPP----PPSPPQPSRLAPYPHPA 204
G PP PPP PP PP PP R AP P P+
Sbjct: 285 GGPPPPPP--PPHNSGPPPPPARGRGAPPPPPS 315
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 68.2 bits (165), Expect = 8e-12
Identities = 59/187 (31%), Positives = 73/187 (39%), Gaps = 27/187 (14%)
Query: 33 APAPLAPYEVLGGAL-EGGLPVGGEPLAGDGFSDWMTERVDFTALLPLEPPLPPGTLPQP 91
AP+P P + + G L P G G + R + A P PP PP LP P
Sbjct: 130 APSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPLPPP 189
Query: 92 SPTP-----PDLEAMASLLKKELEQMEDFFLDAPPLPPPSPPPLPPPPLPPAPSL----- 141
P+ P + L K L + APP PPP PPP P PPLPPA L
Sbjct: 190 LPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTP-PPLPPASVLSDKAV 248
Query: 142 -----PLSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPPLPPPQQPP--------- 187
PL LP P P+L + + ++ PP PPP PP
Sbjct: 249 KPQLAPLHLPPIP-PPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRAS 307
Query: 188 PPSPPQP 194
P+PP P
Sbjct: 308 LPAPPLP 314
Score = 67.8 bits (164), Expect = 1e-11
Identities = 62/210 (29%), Positives = 79/210 (37%), Gaps = 46/210 (21%)
Query: 31 PPAPAPLAPYEVLGGALEGGLPVGGEPLAGDGFSDWMTERVDFTALLPLEPPLPPGTLPQ 90
PP P P P L L P+ ++ G + + + P P PP P
Sbjct: 174 PPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPG----PLTKGNLPVVAPPVPCAPPPPPPP 229
Query: 91 PSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSP----------------------- 127
P PTPP L AS+L + + + L PP+PPP P
Sbjct: 230 PPPTPPPLPP-ASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQE 288
Query: 128 PPLPPPPLPPAPSLPLSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPPLPPPQQPP 187
PP PPPPLPP S P LP PP L + +E PP PP+ P
Sbjct: 289 PPAPPPPLPPYASCS---PRASLPAPP------LPGVNSSSET-------PPPLPPKSPS 332
Query: 188 PPSPPQPSRLAPYPHPATTRGDRK--QKKR 215
+PPQ + P P G + QKKR
Sbjct: 333 FQAPPQKAGAQALPAPPAPPGSQPFLQKKR 362
Score = 56.6 bits (135), Expect = 2e-08
Identities = 36/95 (37%), Positives = 42/95 (44%), Gaps = 19/95 (20%)
Query: 121 PLPPPSPPPLPPPPLPPA--PSLPLSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMP 178
P PPP PP PPPPLPP S P+ P P P L ++A P
Sbjct: 172 PAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVA--------------P 217
Query: 179 PLPPPQQPPPPSPPQPSRLAPYPHPATTRGDRKQK 213
P+P PPPP PP P P P PA+ D+ K
Sbjct: 218 PVPCA--PPPPPPPPPPTPPPLP-PASVLSDKAVK 249
Score = 45.1 bits (105), Expect = 7e-05
Identities = 50/165 (30%), Positives = 62/165 (37%), Gaps = 20/165 (12%)
Query: 31 PPAPAPLAPYEVLGG-ALEGGL-PVGGEPLAGD-------GFSDWMTERVDFTALLPLEP 81
PP P PL P VL A++ L P+ P+ G+ E A EP
Sbjct: 231 PPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPAS-PAQDAQEP 289
Query: 82 PLPPGTLPQPSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPPPLPPPPLPPAPSL 141
P PP LP + P ASL L + PPLPP SP PP A +L
Sbjct: 290 PAPPPPLPPYASCSP----RASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQAL 345
Query: 142 PLSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPPLPPPQQP 186
P P PP + R AG ++ PP PP + P
Sbjct: 346 PAP------PAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSP 384
Score = 39.7 bits (91), Expect = 0.003
Identities = 17/28 (60%), Positives = 18/28 (64%), Gaps = 6/28 (21%)
Query: 121 PLPPPSPPPLPPP------PLPPAPSLP 142
P+PPP PPPLPPP P PP PS P
Sbjct: 2 PVPPPPPPPLPPPPPPLGAPPPPPPSAP 29
Score = 36.6 bits (83), Expect = 0.025
Identities = 17/31 (54%), Positives = 20/31 (64%), Gaps = 1/31 (3%)
Query: 120 PPLPPPSPPPLPPPPLPPAPSLPLSLPSFDL 150
PPLPPP PPPL PP PP + P+S + L
Sbjct: 9 PPLPPP-PPPLGAPPPPPPSAPPVSTDTSSL 38
Score = 35.8 bits (81), Expect = 0.043
Identities = 31/97 (31%), Positives = 36/97 (37%), Gaps = 30/97 (30%)
Query: 81 PPLPP-------GTLPQP--------SPTPPDLEAMASLLKKELEQMEDFFLDAPPLPPP 125
PPLPP +LP P S TPP L + + ++ L APP PP
Sbjct: 294 PPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPG 353
Query: 126 SPP---------------PLPPPPLPPAPSLPLSLPS 147
S P L PPP PPA S L S
Sbjct: 354 SQPFLQKKRHGRPGAGGGKLNPPPAPPARSPTTELSS 390
Score = 34.3 bits (77), Expect = 0.13
Identities = 20/54 (37%), Positives = 23/54 (42%), Gaps = 23/54 (42%)
Query: 77 LPLEPPLPPGTLPQPSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPPPL 130
+P+ PP PP P P P PP L APP PPPS PP+
Sbjct: 1 MPVPPPPPP---PLPPPPPP--------------------LGAPPPPPPSAPPV 31
Score = 33.9 bits (76), Expect = 0.16
Identities = 24/74 (32%), Positives = 27/74 (36%), Gaps = 2/74 (2%)
Query: 132 PPPLPPAPSLPLSLPSFDL--PQPPVLDTLDLLAIYCRNEAGQEEVGMPPLPPPQQPPPP 189
P P+P LP S L P P L R + V PP P P PPPP
Sbjct: 126 PGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPP 185
Query: 190 SPPQPSRLAPYPHP 203
PP +P P
Sbjct: 186 LPPPLPSSSPIKTP 199
Score = 33.5 bits (75), Expect = 0.22
Identities = 13/26 (50%), Positives = 15/26 (57%)
Query: 179 PLPPPQQPPPPSPPQPSRLAPYPHPA 204
P+PPP PP P PP P P P P+
Sbjct: 2 PVPPPPPPPLPPPPPPLGAPPPPPPS 27
Score = 33.5 bits (75), Expect = 0.22
Identities = 19/51 (37%), Positives = 26/51 (50%), Gaps = 7/51 (13%)
Query: 177 MPPLPPPQQPPPP----SPPQPSRLAPYPHPATTRGDRKQKKRDQNKSAAL 223
+PP PPP PPPP +PP P AP P +T ++ + +SA L
Sbjct: 3 VPPPPPPPLPPPPPPLGAPPPPPPSAP---PVSTDTSSLRRADPKGRSALL 50
Score = 33.5 bits (75), Expect = 0.22
Identities = 22/73 (30%), Positives = 31/73 (42%), Gaps = 9/73 (12%)
Query: 134 PLPPAPSLPLSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPPLPPPQQPPPPSPPQ 193
P P P+ +S P P + +T +EA PP P PPPP+PP
Sbjct: 131 PSPRLPNKTISGPLIPPASPRLGNT---------SEAHGAARTAPPRPNVPAPPPPTPPP 181
Query: 194 PSRLAPYPHPATT 206
P P P P+++
Sbjct: 182 PPPPLPPPLPSSS 194
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 67.4 bits (163), Expect = 1e-11
Identities = 47/140 (33%), Positives = 61/140 (43%), Gaps = 12/140 (8%)
Query: 77 LPLEPPLPPGTL---PQPSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPPPLPPP 133
LP PP L P+ SP P E E ++ F ++P PPP PL PP
Sbjct: 561 LPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPP 620
Query: 134 P-----LPPAPSLPLSLPSFDLPQ--PPVLDTLDLLAIYCRNEAGQEEVGMPPLPPPQQP 186
P PP P+S P + P PP + L L + R EE P PPP++
Sbjct: 621 PEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEE--SPLSPPPEES 678
Query: 187 PPPSPPQPSRLAPYPHPATT 206
P PP+ SRL+P P + T
Sbjct: 679 PTSPPPEASRLSPPPEDSPT 698
Score = 56.2 bits (134), Expect = 3e-08
Identities = 39/132 (29%), Positives = 53/132 (40%), Gaps = 17/132 (12%)
Query: 78 PLEPPLPPGTLPQP---SPTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPPPLPPPP 134
PL PP L P SP P E + + E ++ ++P PPP P+ PPP
Sbjct: 535 PLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPP 594
Query: 135 -----LPPAPSLPLSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPPLPPPQQPPPP 189
PP PLS P + P P + + P PPP++ P
Sbjct: 595 EASRLFPPFEESPLSPPPEESPLSPPPEA---------SRLSPPPEDSPMSPPPEESPMS 645
Query: 190 SPPQPSRLAPYP 201
PP+ SRL+P P
Sbjct: 646 PPPEVSRLSPLP 657
Score = 53.1 bits (126), Expect = 3e-07
Identities = 47/138 (34%), Positives = 57/138 (41%), Gaps = 19/138 (13%)
Query: 78 PLEPPLPPGTLPQPSPT----------PPDLEAMASLLKKELEQMEDFFLDAPPLPPPSP 127
P E PL P P+ SPT PP E AS L + L + ++P PPP
Sbjct: 444 PEESPLSPP--PEESPTSPPPEASRLSPPPEELPASPLPEAL-HLSRPLEESPLSPPPEE 500
Query: 128 PPLPPP----PLPPAPSLPLSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPPLPPP 183
PL PP P P PLS P P P + L EE P PPP
Sbjct: 501 SPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEE--SPLSPPP 558
Query: 184 QQPPPPSPPQPSRLAPYP 201
++ P PP+ SRL+P P
Sbjct: 559 EELPTSPPPEASRLSPPP 576
Score = 50.4 bits (119), Expect = 2e-06
Identities = 40/124 (32%), Positives = 50/124 (40%), Gaps = 17/124 (13%)
Query: 80 EPPLPPGTLPQPSPTPPDLEAMASLLKKELEQMEDF----FLDAPPLPPPSPPPLPPPPL 135
E PL P P PP+ + L + L E+ L+ P PPP PL
Sbjct: 491 ESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLS---- 546
Query: 136 PPAPSLPLSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPPLPPPQQPPPPSPPQPS 195
PP PLS P +LP P + R EE P PPP++ P PP+ S
Sbjct: 547 PPFEESPLSPPPEELPTSPPPEA-------SRLSPPPEE--SPMSPPPEESPMSPPPEAS 597
Query: 196 RLAP 199
RL P
Sbjct: 598 RLFP 601
Score = 47.4 bits (111), Expect = 1e-05
Identities = 47/130 (36%), Positives = 52/130 (40%), Gaps = 31/130 (23%)
Query: 78 PLEPPLPPGTLPQPSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPPPLPPPPLPP 137
P E PL P P+ SPT P EA S L E D+P PPP P PPP
Sbjct: 666 PEESPLSPP--PEESPTSPPPEA--SRLSPPPE-------DSPTSPPPEDSPASPPPEDS 714
Query: 138 APSLPL-SLPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPPLPP-PQQP---PPPSPP 192
SLPL P LP+ P L C G P L P P++P P P P
Sbjct: 715 LMSLPLEESPLLPLPEEPQL---------CPRSEG------PHLSPRPEEPHLSPRPEEP 759
Query: 193 QPSRLAPYPH 202
S A PH
Sbjct: 760 HLSPQAEEPH 769
Score = 46.2 bits (108), Expect = 3e-05
Identities = 46/161 (28%), Positives = 66/161 (40%), Gaps = 38/161 (23%)
Query: 49 GGLPVGGEPLAGDGFSDWMTERVDFTALLP---LEPPLPPGTL---PQPSPTPPDLEAMA 102
GG G E + D DW+ + F A+LP L+ L +L P+P PP +
Sbjct: 4839 GGKEKGLEGKSPDTGPDWLKQ---FDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYT 4895
Query: 103 SLLKKELEQMEDFFLDAPPLPPPSPPPLPPPPLPPAPSLPLSLPSFDLPQPPVLDTLDLL 162
+ ++ L APP PSPPP PL P+P+ P + P +LP P+ +
Sbjct: 4896 Y----NVSNLDVRQLSAPPPEEPSPPP---SPLAPSPASPPTEPLVELPTEPLAE----- 4943
Query: 163 AIYCRNEAGQEEVGMPPLPPPQQPPPPSPPQPSRLAPYPHP 203
PP+P P P S P+ +R P P
Sbjct: 4944 ---------------PPVPSPL--PLASSPESARPKPRARP 4967
Score = 45.4 bits (106), Expect = 5e-05
Identities = 31/87 (35%), Positives = 40/87 (45%), Gaps = 14/87 (16%)
Query: 118 DAPPLPPP-----SPPPLPPPPLPPAPSLPLSLPSFDLPQPPVLDTLDLLAIYCRNEAGQ 172
+ P LPPP SPPP P PP + LS P +LP P+ + L L
Sbjct: 437 EMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHL-------SRPL 489
Query: 173 EEVGMPPLPPPQQPPPPSPPQPSRLAP 199
EE P PPP++ P PP+ S +P
Sbjct: 490 EE--SPLSPPPEESPLSPPPESSPFSP 514
Score = 45.1 bits (105), Expect = 7e-05
Identities = 54/185 (29%), Positives = 70/185 (37%), Gaps = 19/185 (10%)
Query: 32 PAPAPLAPYEVLGGALEGGLPVGGE---PLAGDGFSDWMTERVDFTALLPLEPPLPPGTL 88
P P PL+P ++ A L GE P G SD + P+ PP P
Sbjct: 934 PLPPPLSP--IITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPP-PEANC 990
Query: 89 PQPSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPP----PLPPPPLPPA----PS 140
P P PP + + + ++ PLPP P L P PP+ P+
Sbjct: 991 TDPEPVPPMI--LPPSPGSPVGPASPILME--PLPPQCSPLLQHSLVPQNSPPSQCSPPA 1046
Query: 141 LPLSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPPLPPPQQPPPPSP-PQPSRLAP 199
LPLS+PS P V+ D ++ E P L P P PSP S AP
Sbjct: 1047 LPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAP 1106
Query: 200 YPHPA 204
P PA
Sbjct: 1107 SPAPA 1111
Score = 44.3 bits (103), Expect = 1e-04
Identities = 44/143 (30%), Positives = 52/143 (36%), Gaps = 20/143 (13%)
Query: 78 PLEPPLPPGTLPQPSPTP----PDLEAMASLLKKEL--EQMEDFFLDAP---PLPPPSPP 128
P +PP PG P P P P +++ LL + E E P PL P P
Sbjct: 864 PEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEP 923
Query: 129 PLPPPPLPPAPSLPLSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEE----VGMPPLPPPQ 184
L P +PP P P P PP L L L Y G + + P L P
Sbjct: 924 SLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELE-YPFGAKGDSDPESPLAAPILETPI 982
Query: 185 QPPP------PSPPQPSRLAPYP 201
PPP P P P L P P
Sbjct: 983 SPPPEANCTDPEPVPPMILPPSP 1005
Score = 42.0 bits (97), Expect = 6e-04
Identities = 41/135 (30%), Positives = 56/135 (41%), Gaps = 19/135 (14%)
Query: 78 PLEPPLPPGTLPQPSPTPPDLEAMASL--LKKELEQMEDFFLDAPPLP-PPSPPPLPPPP 134
P + P+ P P PP++ ++ L + + E+ L PP P SPPP
Sbjct: 630 PEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRL 689
Query: 135 LPPAPSLPLSLPSFDLP-QPPVLDTLDLLAIYCRNEAGQEEVGMPPLP------PPQQPP 187
PP P S P D P PP D+L L + EE + PLP P + P
Sbjct: 690 SPPPEDSPTSPPPEDSPASPPPEDSLMSLPL--------EESPLLPLPEEPQLCPRSEGP 741
Query: 188 PPSP-PQPSRLAPYP 201
SP P+ L+P P
Sbjct: 742 HLSPRPEEPHLSPRP 756
Score = 41.6 bits (96), Expect = 8e-04
Identities = 41/127 (32%), Positives = 48/127 (37%), Gaps = 13/127 (10%)
Query: 77 LPLEPPLPPGTLPQPSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPPPLPPPPLP 136
+P EP L P P+ S P E + E + L+ PPL SP P PP P
Sbjct: 818 VPEEPCLSPQ--PEESHLSPQSEEPCLSPRPEESHLSPE-LEKPPL---SPRPEKPPEEP 871
Query: 137 PAPSLPLSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPPLPPPQQPPPPSPPQPSR 196
P LP F P P L L E E G PPL P + P SP
Sbjct: 872 GQCPAPEELPLFPPPGEPSLSPL-------LGEPALSEPGEPPLSPLPEELPLSPSGEPS 924
Query: 197 LAPYPHP 203
L+P P
Sbjct: 925 LSPQLMP 931
Score = 38.1 bits (87), Expect = 0.009
Identities = 34/122 (27%), Positives = 41/122 (33%), Gaps = 8/122 (6%)
Query: 82 PLPPGTLPQPSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPPPLPPPPLPPAPSL 141
P PG +P PP A L D F P + PPL P P PP P
Sbjct: 2340 PQSPGLGLRPQEPPP-----AQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPES 2394
Query: 142 PLSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPPLPPPQQPPPPSPPQPSRLAPYP 201
+LP LP P + A + Q + PL P P P+ PY
Sbjct: 2395 CCALPPRSLPSDPF---SRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYS 2451
Query: 202 HP 203
P
Sbjct: 2452 RP 2453
Score = 37.4 bits (85), Expect = 0.015
Identities = 37/128 (28%), Positives = 47/128 (36%), Gaps = 32/128 (25%)
Query: 81 PPLPPGTLPQPSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPPPLPPPP--LPPA 138
P LPP P+ SP P E ++P PPP L PPP LP +
Sbjct: 439 PLLPP---PEESPLSPPPE------------------ESPTSPPPEASRLSPPPEELPAS 477
Query: 139 P---SLPLSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPPLPPPQQPPPPSPPQPS 195
P +L LS P + P P + L + + P P PP SPP P+
Sbjct: 478 PLPEALHLSRPLEESPLSPPPEESPL------SPPPESSPFSPLEESPLSPPEESPPSPA 531
Query: 196 RLAPYPHP 203
P P
Sbjct: 532 LETPLSPP 539
Score = 37.4 bits (85), Expect = 0.015
Identities = 38/139 (27%), Positives = 48/139 (34%), Gaps = 30/139 (21%)
Query: 76 LLPLEPPLPPGTLPQPSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPPP------ 129
L P EPP P P P+ PD+ S D + P P P PPP
Sbjct: 2347 LRPQEPPPAQALAPSP-PSHPDIFRPGSYT--------DPYAQPPLTPRPQPPPPESCCA 2397
Query: 130 LPPPPLPPAP--SLPLSLPSFDLPQPPVLDTLDLLAIYCRNEA-----GQEEVGMPP--- 179
LPP LP P +P S S Q P+ +C + + PP
Sbjct: 2398 LPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRP 2457
Query: 180 -----LPPPQQPPPPSPPQ 193
P +PP P PP+
Sbjct: 2458 QSRDPFAPLHKPPRPQPPE 2476
Score = 36.6 bits (83), Expect = 0.025
Identities = 31/109 (28%), Positives = 41/109 (37%), Gaps = 14/109 (12%)
Query: 96 PDLEAMASLLKKELEQMEDFFLDAPPLPPPSPPPLPPPPLPPAPSLPLSLPSFDLPQPPV 155
P LEA + L E+ L PP P+ PP L P P LP+ LP+
Sbjct: 428 PQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPE---ELPASPLPE--- 481
Query: 156 LDTLDLLAIYCRNEAGQEEVGMPPLPPPQQPPPPSPP-QPSRLAPYPHP 203
A++ + + PP P PPP S P P +P P
Sbjct: 482 -------ALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPP 523
Score = 33.9 bits (76), Expect = 0.16
Identities = 43/148 (29%), Positives = 49/148 (33%), Gaps = 39/148 (26%)
Query: 77 LPLEPPLPPGTLPQPSP------------TPPDLEAMASLLKKEL-------EQMEDFFL 117
L L P PG L P P TP L A K + + FL
Sbjct: 2102 LHLRIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFL 2161
Query: 118 DAPPLPPPSPPPLPPPPLPPA-------PSLPLSLPSFDLP-----QPPVLDTLDLLAIY 165
PP P P P L PA P+ P + P + P QPP +L
Sbjct: 2162 KLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPP------MLGAS 2215
Query: 166 CRNEAGQ--EEVGMPPLPPPQQPPPPSP 191
R AGQ E PP P QP P P
Sbjct: 2216 SRPGAGQPGEFHTTPPGTPRHQPSTPDP 2243
Score = 32.0 bits (71), Expect = 0.63
Identities = 31/121 (25%), Positives = 42/121 (34%), Gaps = 27/121 (22%)
Query: 99 EAMASLLKKELEQMEDFFLDAPPLPPPSPPPLPPPPLPPAPSLPLSLPSFDLPQPPVLDT 158
+ A L++++L+Q + PP P PL L F PQ L
Sbjct: 4221 QLQALLMQRQLQQSQA----VRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQE 4276
Query: 159 LDLLAIYCRNEAGQEEVGMPPLPPPQ--------------QPPPPSPPQPSRLAPYPHPA 204
L AG G P LP P PPP SP +P R + P P+
Sbjct: 4277 LG---------AGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPS 4327
Query: 205 T 205
+
Sbjct: 4328 S 4328
Score = 31.6 bits (70), Expect = 0.82
Identities = 49/176 (27%), Positives = 63/176 (35%), Gaps = 32/176 (18%)
Query: 29 KLPPAPAPLAPYEVLGGALEG---GLPVGGEPLAGD-GFSDWMTERVDFTALLPLEPPLP 84
+ P P P + LG L G LP GEP+ G G + ++ R + ++ L
Sbjct: 2836 RFPSTPGPELGRQALGSPLAGISTRLPGPGEPVPGPAGPAQFIELRHN------VQKGLG 2889
Query: 85 PGTLPQPSPTPPDLEAMASLLKKELEQMEDFFLDAPP-LPPPSPPPLPP--PPLPPAPSL 141
PG P P PP + ED AP L + LPP P PPAP L
Sbjct: 2890 PGGTPFPGQGPPQRPRFYPV-------SEDPHRLAPEGLRGLAVSGLPPQKPSAPPAPEL 2942
Query: 142 PLSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPPLPPPQQPPPPSPPQPSRL 197
SL + P L T G E V PP P P + +L
Sbjct: 2943 NNSLHPTPHTKGPTLPT------------GLELVNRPPSSTELGRPNPLALEAGKL 2986
Score = 31.6 bits (70), Expect = 0.82
Identities = 25/90 (27%), Positives = 30/90 (33%), Gaps = 11/90 (12%)
Query: 121 PLPPPSPP---------PLPPPPLPPAPSLPLSLPSFDLPQPPVLDTLDLLAIYCRNEAG 171
P PPPS P P P LP LP + P PQ P L+ +
Sbjct: 4307 PTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLA 4366
Query: 172 QE--EVGMPPLPPPQQPPPPSPPQPSRLAP 199
G+ P PP P+ S L P
Sbjct: 4367 DTLFSKGLGPWDPPDNLAETQKPEQSSLVP 4396
Score = 31.2 bits (69), Expect = 1.1
Identities = 41/157 (26%), Positives = 54/157 (34%), Gaps = 38/157 (24%)
Query: 5 ATLGLELDRALL--PASGLGW-LVDYGKLPPAPAPLAPYEVLGGALEGGLPVGGEPLAGD 61
+T G EL R L P +G+ L G+ P PA A + L ++ GL GG P G
Sbjct: 2839 STPGPELGRQALGSPLAGISTRLPGPGEPVPGPAGPAQFIELRHNVQKGLGPGGTPFPGQ 2898
Query: 62 GFSDWMTERVDFTALLPLEPPLPPGTLPQPSPTPPDLEAMASLLKKELEQMEDFFLDAPP 121
G P P+ P D +A E + + P
Sbjct: 2899 G----------------------PPQRPRFYPVSEDPHRLAP------EGLRGLAVSGLP 2930
Query: 122 LPPPSPPPLP-------PPPLPPAPSLPLSLPSFDLP 151
PS PP P P P P+LP L + P
Sbjct: 2931 PQKPSAPPAPELNNSLHPTPHTKGPTLPTGLELVNRP 2967
Score = 30.8 bits (68), Expect = 1.4
Identities = 19/59 (32%), Positives = 25/59 (42%), Gaps = 4/59 (6%)
Query: 82 PLPPGTLPQPSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPPPLPPPPLPPAPS 140
P PP + PQ P L + +S L E + P P P P L PPP +P+
Sbjct: 4307 PTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTH----PGTPKPQGPTLEPPPGRVSPA 4361
Score = 28.9 bits (63), Expect = 5.3
Identities = 28/94 (29%), Positives = 32/94 (34%), Gaps = 24/94 (25%)
Query: 112 MEDFFLDAPPLPPPSPPPLPPPPLPP-------------------APSLPLSLPSFDLPQ 152
+E F APP PP P P P PP P P PS P
Sbjct: 2185 LEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPS--TPD 2242
Query: 153 P---PVLDTLDLLAIYCRNEAGQEEVGMPPLPPP 183
P P +LD LA+ G + P L PP
Sbjct: 2243 PFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPP 2276
Score = 28.9 bits (63), Expect = 5.3
Identities = 24/68 (35%), Positives = 25/68 (36%), Gaps = 2/68 (2%)
Query: 76 LLPLEPPLPPGTLPQPSPT-PPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPPPLPPPP 134
L P P PP P PSPT P M + F PP P P P P
Sbjct: 2185 LEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPF 2244
Query: 135 LPP-APSL 141
L P PSL
Sbjct: 2245 LKPRCPSL 2252
Score = 28.9 bits (63), Expect = 5.3
Identities = 24/82 (29%), Positives = 28/82 (34%), Gaps = 23/82 (28%)
Query: 120 PPLPPPSPPPLPPPPLPPAPSLPLSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPP 179
P L P P P PP P P P LPS P E +PP
Sbjct: 4300 PVLGPVHPTP--PPSSPQEPKRPSQLPSPSSQLP-------------------TEAQLPP 4338
Query: 180 LPP--PQQPPPPSPPQPSRLAP 199
P P+ P P P R++P
Sbjct: 4339 THPGTPKPQGPTLEPPPGRVSP 4360
Score = 28.9 bits (63), Expect = 5.3
Identities = 11/17 (64%), Positives = 11/17 (64%)
Query: 117 LDAPPLPPPSPPPLPPP 133
L PP PP S PP PPP
Sbjct: 4616 LSNPPTPPSSLPPTPPP 4632
>gi|47132519 Ras association and pleckstrin homology domains 1
isoform 1 [Homo sapiens]
Length = 1250
Score = 65.5 bits (158), Expect = 5e-11
Identities = 52/173 (30%), Positives = 61/173 (35%), Gaps = 50/173 (28%)
Query: 77 LPLEPPLPPGTLPQPSPTPPDLEAMAS---------------LLKKELEQMEDFFLDAPP 121
LP PP PP P P P PP L + ++ + + + L PP
Sbjct: 628 LPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPP 687
Query: 122 LPP-------------------PSPPPLPPPPLP--------PAPSLPLSLPSFDLPQPP 154
PP P PPP PPPP P PAP P SLP F P PP
Sbjct: 688 TPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAP-SLPQFSAPPPP 746
Query: 155 VLDTLDLLAIYCRNEAGQEEVGMPPLPPPQQPPPPSPPQPSRLAPYPHPATTR 207
L I+ Q PP PPP P P P L P P +T+
Sbjct: 747 -------LKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTK 792
Score = 58.5 bits (140), Expect = 6e-09
Identities = 41/120 (34%), Positives = 54/120 (45%), Gaps = 49/120 (40%)
Query: 119 APPLPPPSPPPLPPPPLPPAPSLPL---SLPS---------------------------F 148
+PPLPPP PPP PPPP PP P PL S PS F
Sbjct: 625 SPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALF 684
Query: 149 DLPQPPVLDTLDLLAIYCRNEAGQEEVGMPP---LPPPQQPPPPSPPQP----SRLAPYP 201
P PPV+ ++++ + ++ +PP +PPP PPPP PP P ++L P P
Sbjct: 685 KPPTPPVM----------QSQSVKPQILVPPNGVVPPP--PPPPPPPTPGSAMAQLKPAP 732
Score = 57.4 bits (137), Expect = 1e-08
Identities = 45/144 (31%), Positives = 57/144 (39%), Gaps = 34/144 (23%)
Query: 78 PLEPPLPPGTLPQPSPTP-----PDLEAMASLLKKELEQMEDFFLDAPPLPPPSPPPLP- 131
P PP P + Q P P P A LK + Q++ APP PPP PPP+P
Sbjct: 715 PPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLK--IHQVQHITQVAPPTPPP-PPPIPA 771
Query: 132 --PPPLPPAPSLPLSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPPLPPPQQPP-- 187
PP PP P + + P+ PV+ PP+PP ++ P
Sbjct: 772 PLPPQAPPKPLVTIPAPTSTKTVAPVV------------TQAAPPTPTPPVPPAKKQPAF 819
Query: 188 -----PPSPPQPSRLAPYPHPATT 206
PPSPP P P P P T
Sbjct: 820 PASYIPPSPPTP----PVPVPPPT 839
Score = 55.8 bits (133), Expect = 4e-08
Identities = 45/165 (27%), Positives = 60/165 (36%), Gaps = 54/165 (32%)
Query: 77 LPLEPPLPPGTLPQPS----------PTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPS 126
+P PP PP +P P+ P P L + S++K+ Q PPP+
Sbjct: 824 IPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFP---------PPPT 874
Query: 127 PP-----PLPPPPLPPAPSLP-------------LSLPSFDLPQPPVLDTLDLLAIYCRN 168
PP PL P P AP P + +PS D P PP +L
Sbjct: 875 PPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVF------- 927
Query: 169 EAGQEEVGMPPLPPPQQPPPPSPPQPSRLAPYPHPATTRGDRKQK 213
P PPP P P PP P +P P + + G + K
Sbjct: 928 ----------PPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSK 962
Score = 53.9 bits (128), Expect = 2e-07
Identities = 42/142 (29%), Positives = 57/142 (40%), Gaps = 27/142 (19%)
Query: 78 PLEPPLPPGTLPQPS---PTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPPPLPPPP 134
P+ PLPP P+P P P + +A ++ + APP P P PP P
Sbjct: 768 PIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQA----------APPTPTPPVPPAKKQP 817
Query: 135 LPPAPSLPLSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPPL--------PPPQQP 186
PA +P S P+ +P PP TL +C +P + PPP P
Sbjct: 818 AFPASYIPPSPPTPPVPVPP--PTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTP 875
Query: 187 P----PPSPPQPSRLAPYPHPA 204
P P P P+ +AP PA
Sbjct: 876 PAMESQPLKPVPANVAPQSPPA 897
Score = 51.6 bits (122), Expect = 8e-07
Identities = 60/216 (27%), Positives = 78/216 (36%), Gaps = 45/216 (20%)
Query: 31 PPAPAPLAPYEVLGGALEGGLPVGGEPLAGDGFSDWMTERVDFTALLPL-----EPPLPP 85
PP PAPL P A L P + + +T+ T P+ +P P
Sbjct: 767 PPIPAPLPPQ-----APPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPA 821
Query: 86 GTLPQPSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPPP---------LPPPPLP 136
+P PTPP +L K++ F PP P SP P PPPP P
Sbjct: 822 SYIPPSPPTPPVPVPPPTLPKQQS------FCAKPPPSPLSPVPSVVKQIASQFPPPPTP 875
Query: 137 PA-PSLPLS-LPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPPLPPPQQPPPPS---- 190
PA S PL +P+ PQ P A+ + + + P+P P PPPP
Sbjct: 876 PAMESQPLKPVPANVAPQSPP-------AVKAKPKWQPSSI---PVPSPDFPPPPPESSL 925
Query: 191 ----PPQPSRLAPYPHPATTRGDRKQKKRDQNKSAA 222
PP AP P P T K K +
Sbjct: 926 VFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTS 961
Score = 41.6 bits (96), Expect = 8e-04
Identities = 39/144 (27%), Positives = 53/144 (36%), Gaps = 40/144 (27%)
Query: 80 EPPLPPGTLPQPSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPPPLPPPPLPP-- 137
+P P ++P PSP P +SL+ P PPPSP P PPPP PP
Sbjct: 901 KPKWQPSSIPVPSPDFPPPPPESSLVF--------------PPPPPSPVPAPPPPPPPTA 946
Query: 138 --------APSLPLSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPPL--------P 181
+P S S + P +I + A E P + P
Sbjct: 947 SPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTP 1006
Query: 182 PPQQ--------PPPPSPPQPSRL 197
P + PPP +PP+P +L
Sbjct: 1007 PAESGSPSKETLPPPAAPPKPGKL 1030
Score = 38.5 bits (88), Expect = 0.007
Identities = 42/174 (24%), Positives = 49/174 (28%), Gaps = 42/174 (24%)
Query: 81 PPLPPGTLPQPSPTPPDL-----EAMASLLKKELEQMEDFFLDAPPLPP----------- 124
PP PP +P P P PP + S KK + PP P
Sbjct: 928 PPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGA 987
Query: 125 -------------------------PSPPPLPPPPLPPAPSLPLSLPSFDLPQPPVLDTL 159
PS LPPP PP P L+L +LP +
Sbjct: 988 EHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPG-KLNLSGVNLPGVLQQGCV 1046
Query: 160 DLLAIYCRNEAGQEEVGMPPLPPPQQPPPPSPPQPSRLAPYPHPATTRGDRKQK 213
A V P P PPP P L P PA G+ K
Sbjct: 1047 SAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPK 1100
Score = 35.8 bits (81), Expect = 0.043
Identities = 22/72 (30%), Positives = 26/72 (36%), Gaps = 22/72 (30%)
Query: 133 PPLPPAPSLPLSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPPLPPPQQPPPPSPP 192
PPL P P + + P PP+ PP PPP PPPP PP
Sbjct: 607 PPLSPQPKIVTPYTASQ-PSPPL---------------------PPPPPPPPPPPPPPPP 644
Query: 193 QPSRLAPYPHPA 204
P L P+
Sbjct: 645 PPPPLPSQSAPS 656
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 65.1 bits (157), Expect = 7e-11
Identities = 59/148 (39%), Positives = 64/148 (43%), Gaps = 35/148 (23%)
Query: 77 LPLEPPLPPG-----TLPQPSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPP---PSP- 127
LPL PP P TLP P TPP +A SL L+ F L +PPL P P P
Sbjct: 338 LPLAPPSPSAPPSLQTLPSPPATPPS-QATTSLGSPTLQATHSF-LPSPPLSPLATPPPQ 395
Query: 128 -------PPLPPPPLPPA--PSLPLSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMP 178
PPL PP PPA P PL+ PS PQ P + LL Q P
Sbjct: 396 APPALALPPLQAPPSPPASPPLSPLATPS---PQAPNALAVHLL---------QAPFSPP 443
Query: 179 PLPPPQQP--PPPSPP-QPSRLAPYPHP 203
P PP Q P PP SPP PS P P
Sbjct: 444 PSPPVQAPFSPPASPPVSPSATPPSQAP 471
Score = 62.0 bits (149), Expect = 6e-10
Identities = 68/205 (33%), Positives = 76/205 (37%), Gaps = 47/205 (22%)
Query: 31 PPAPAPLAPYEVLGGALEGGLPVGGEPLAGDGFSDWMTERVDFTALLPLEPPLPPGTLPQ 90
PPA PL+P L V L FS + V P PP+ P P
Sbjct: 411 PPASPPLSPLATPSPQAPNALAVH---LLQAPFSPPPSPPVQAPFSPPASPPVSPSATP- 466
Query: 91 PSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPPPLPPPPLPPAPSLPLSLPSFDL 150
PS PP L A L PP PP SPP P PP PL+ P L
Sbjct: 467 PSQAPPSLAAPP--------------LQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQL 512
Query: 151 ----PQ-PPVLDTLDLLAIYCRNEA--GQE------EVGMPPL--PPPQQPP-------- 187
PQ PP L T L A+ + GQ + M PL PPPQ PP
Sbjct: 513 AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQ 572
Query: 188 -PPSPP-----QPSRLAPYPHPATT 206
PPSPP Q R P P P T+
Sbjct: 573 VPPSPPASPTLQAPRRPPTPGPDTS 597
Score = 44.7 bits (104), Expect = 9e-05
Identities = 44/144 (30%), Positives = 51/144 (35%), Gaps = 39/144 (27%)
Query: 78 PLEPPLPPGTLPQPSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPPPLPPPPLPP 137
PL P P L +P +S L +L A PLP P P PP L
Sbjct: 303 PLATPSPSAALQSQAPPTLPATPHSSSLTCQL---------ATPLPLAPPSPSAPPSLQT 353
Query: 138 APSLPLSLPS---FDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPPL-----PPPQQPP-- 187
PS P + PS L P + T L PPL PPPQ PP
Sbjct: 354 LPSPPATPPSQATTSLGSPTLQATHSFLP-------------SPPLSPLATPPPQAPPAL 400
Query: 188 -------PPSPPQPSRLAPYPHPA 204
PPSPP L+P P+
Sbjct: 401 ALPPLQAPPSPPASPPLSPLATPS 424
Score = 35.0 bits (79), Expect = 0.074
Identities = 54/200 (27%), Positives = 62/200 (31%), Gaps = 28/200 (14%)
Query: 34 PAPLAPYEVLGGALEGGLPVGGEP--LAGDGFSDWMTERVDFTALLPLEPP--LPPGTLP 89
P P AP + L+ P P LA + F P P LP L
Sbjct: 497 PPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLA 556
Query: 90 QPSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPP--------------PLPPPPL 135
P P P + A A LL+ L AP PP P P PPPP
Sbjct: 557 TPPPQAPPVLA-APLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPP 615
Query: 136 PPAPSLPLSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPP------LPPPQQPPPP 189
+PS LS P T + L Y G PP P P
Sbjct: 616 SRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGP 675
Query: 190 SPPQPSR---LAPYPHPATT 206
+PP R AP P P T
Sbjct: 676 APPLAFRGAPGAPLPWPPAT 695
Score = 34.3 bits (77), Expect = 0.13
Identities = 37/146 (25%), Positives = 48/146 (32%), Gaps = 27/146 (18%)
Query: 74 TALLPLEPPLPPGTLPQPSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPPP---- 129
T L PP PP P + + PDL +S E++ + SPPP
Sbjct: 604 TLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAEL 663
Query: 130 --LPPPPLPPAPSLPLSL---PSFDLPQPPVLD--TLDLLAIYCRNEAGQEEVGMPPLPP 182
P P+ PL+ P LP PP + D L E
Sbjct: 664 AACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEG------------ 711
Query: 183 PQQPPPPSPPQPSRLAPYPHPATTRG 208
P + P P L P P P T+ G
Sbjct: 712 ----PESATPAPGALDPGPSPGTSGG 733
Score = 31.2 bits (69), Expect = 1.1
Identities = 43/157 (27%), Positives = 55/157 (35%), Gaps = 24/157 (15%)
Query: 57 PLAGDGFSDWMTERVDFTALLPLEPPLPPGTLPQPSPTPPDLEAMASLLKKELEQMEDFF 116
P AG G + + +A PL P G + +P P + K L+ +
Sbjct: 228 PSAGGGLQRPASRSLSSSAT-PLSSPARSGPSARGTPRAPAHPSQPK--PKGLQALR--- 281
Query: 117 LDAPPLPPPSPPPLPP--PPLPPAPSLPLSLPS----FDLPQPPVLD-TLDLLAIYCRNE 169
PP PP P L P S PL+ PS PP L T ++ C
Sbjct: 282 ------PPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTC--- 332
Query: 170 AGQEEVGMPPLPPPQQPPPPSPPQPSRLAPYPHPATT 206
Q +P PP PP PS A P ATT
Sbjct: 333 --QLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATT 367
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 64.3 bits (155), Expect = 1e-10
Identities = 48/137 (35%), Positives = 55/137 (40%), Gaps = 34/137 (24%)
Query: 78 PLEPPLPPGTLPQPSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPPPLP---PPP 134
P PPL P P P L + S E +E+ PP PPP+P P P PPP
Sbjct: 1419 PDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEE---KPPPTPPPAPTPQPQPPPPP 1475
Query: 135 LPPAPSL----PLSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPPLPPPQQPPPPS 190
PP P+L PL P+ P PP L PP PPP P PP
Sbjct: 1476 PPPQPALPSPPPLVAPTPSSPPPPPL---------------------PPPPPPAMPSPPP 1514
Query: 191 PPQPSR---LAPYPHPA 204
PP P+ AP PA
Sbjct: 1515 PPPPAAAPLAAPPEEPA 1531
Score = 55.5 bits (132), Expect = 5e-08
Identities = 66/201 (32%), Positives = 78/201 (38%), Gaps = 35/201 (17%)
Query: 16 LPASGLGWLVDYGKLPPAPAPLAPYEVLGGALEGGLPVGGEPLAGDGFSDWMTERVDFTA 75
+PA GL P P P + LGGALE G G G +R+D
Sbjct: 1317 VPARGLQPQPPATPAVPHPPPSGAFG-LGGALEAAESEG----LGLGCPS-PCKRLDEEL 1370
Query: 76 LLPLEPPLPPGTLPQPSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSP------PP 129
LE TLP S D A L++ + LD PPL P PP
Sbjct: 1371 KRNLE------TLPSFSSDEEDSVAKNRDLQESISSAISA-LDDPPLAGPKDTSTPDGPP 1423
Query: 130 LPP----PPLPPAPSLPLSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPPLPPPQQ 185
L P P PP P LP S S P+PP+L+ E P P PQ
Sbjct: 1424 LAPAAAVPGPPPLPGLP-SANSNGTPEPPLLE-----------EKPPPTPPPAPTPQPQP 1471
Query: 186 PPPPSPPQPSRLAPYPHPATT 206
PPPP PPQP+ +P P A T
Sbjct: 1472 PPPPPPPQPALPSPPPLVAPT 1492
Score = 47.8 bits (112), Expect = 1e-05
Identities = 43/133 (32%), Positives = 51/133 (38%), Gaps = 19/133 (14%)
Query: 32 PAPAPLAPYEVLGGALEGGLPVGGEPLAGDGFSDWMTERVDFTALLPLEPPL--PPGTLP 89
P PLAP A+ G P+ G P A + LL +PP PP P
Sbjct: 1419 PDGPPLAP----AAAVPGPPPLPGLPSAN-------SNGTPEPPLLEEKPPPTPPPAPTP 1467
Query: 90 QPSPTPPDLEAMASLLKKE-LEQMEDFFLDAPPLPPPSPP-----PLPPPPLPPAPSLPL 143
QP P PP +L L PPLPPP PP P PPPP + P
Sbjct: 1468 QPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPP 1527
Query: 144 SLPSFDLPQPPVL 156
P+ P+ P L
Sbjct: 1528 EEPAAPSPEDPEL 1540
Score = 46.6 bits (109), Expect = 2e-05
Identities = 38/119 (31%), Positives = 46/119 (38%), Gaps = 27/119 (22%)
Query: 75 ALLPLEPPLPPGTLPQPSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPPPLPPPP 134
A L PP PP T PTP L +E D P + PP PP L P
Sbjct: 758 AFLQKSPPPPPPTAQSTQPTPHGL------------LLEAGGPDLPLVLPPPPPQLLPSV 805
Query: 135 LPPAPSLPLSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPPLPPPQQPPPPSPPQ 193
L APS P P + + ++ A ++ PP PPP PPPP P Q
Sbjct: 806 LSHAPS----------PSP----SASKVGVHLLEPATRDGAPQPPPPPP-PPPPPMPLQ 849
Score = 42.7 bits (99), Expect = 4e-04
Identities = 31/103 (30%), Positives = 43/103 (41%), Gaps = 21/103 (20%)
Query: 110 EQMEDFFLDAPPLPPPSPPPLPPPP---------------LPPAPSLPLSLPSFDLPQPP 154
+++ F +PP PPP+ P P LPP P P LPS P
Sbjct: 754 KELGAFLQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPP--PQLLPSVLSHAPS 811
Query: 155 VLDTLDLLAIYCRNEAGQEEVGMPPLPPPQQPPPPSPPQPSRL 197
+ + ++ A ++ G P PPP PPPP PP P +L
Sbjct: 812 PSPSASKVGVHLLEPATRD--GAPQPPPP--PPPPPPPMPLQL 850
Score = 38.5 bits (88), Expect = 0.007
Identities = 42/141 (29%), Positives = 54/141 (38%), Gaps = 24/141 (17%)
Query: 17 PASGLGWLVDYGKLPPAPAPLAPYEVLGGALEGGLPVGGEPLAGDGFSDWMTERVDFTAL 76
PA+GL D L P+ AP P + L GG +G AG G + R
Sbjct: 178 PANGLLSPHDVLHLKPSQAPTVPSSLGFERLAGGGVLGP---AGLGPAQTPPYRPG---- 230
Query: 77 LPLEPPLPPGTLPQPSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPS---------- 126
P +PP PP LP A A+ ++ Q+ +F AP PPP
Sbjct: 231 -PPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQDTVI 289
Query: 127 ------PPPLPPPPLPPAPSL 141
PPPP PPA +L
Sbjct: 290 KHYQRPASAQPPPPPPPAHAL 310
Score = 35.0 bits (79), Expect = 0.074
Identities = 58/209 (27%), Positives = 75/209 (35%), Gaps = 36/209 (17%)
Query: 24 LVDYGKLPPAPAP-LAPYEVLG---------GALEGGLPVGGEPLAGDGFSDWMTERVDF 73
L +G P AP+P L P E L GALE P G+ G S+ +
Sbjct: 854 LRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAY 913
Query: 74 TALLPLEPPLPPGTLPQPSPTPPDLEAMASLLKKE-------LEQM------EDFFLDAP 120
+ P + P +P S PD SLL+ E +E+M +D+ P
Sbjct: 914 RSPSP-QGTKAPRFVPLTSICFPD-----SLLQDEERSFFPTMEEMFGGGAADDYGKAGP 967
Query: 121 PLPP------PSPPPLPPPPLPPAPSLPLSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEE 174
P PPP PP P P P S P+ P L + E
Sbjct: 968 PEDEGDPKAGAGPPPGPPAYDPYGPYCP-GRASGAGPETPGLGLDPNKPPELPSTVNAEP 1026
Query: 175 VGMPPLPPPQQPPPPSPPQPSRLAPYPHP 203
+G+ P Q PPP PP P AP P
Sbjct: 1027 LGLIQSGPHQAAPPPPPPPPPPPAPASEP 1055
Score = 34.3 bits (77), Expect = 0.13
Identities = 28/83 (33%), Positives = 34/83 (40%), Gaps = 5/83 (6%)
Query: 121 PLPPPSPPPLPPPPL-PPAPSL--PLSLPSFDLPQPPVL-DTLDLLAIYCRNEAGQEEVG 176
P P PS L PP PPA L P + Q P + +L + G +G
Sbjct: 161 PFPVPSSLSLQDPPFSPPANGLLSPHDVLHLKPSQAPTVPSSLGFERLAGGGVLGPAGLG 220
Query: 177 MPPLPPPQQPPPPSPPQPSRLAP 199
P PP +P PP PP P R P
Sbjct: 221 -PAQTPPYRPGPPDPPPPPRHLP 242
Score = 33.5 bits (75), Expect = 0.22
Identities = 26/68 (38%), Positives = 28/68 (41%), Gaps = 15/68 (22%)
Query: 78 PLEPPLPPGTLP-QPSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPPPLPPPPLP 136
P PPLPP P PSP PP A A L APP P +P P P LP
Sbjct: 1496 PPPPPLPPPPPPAMPSPPPPPPPAAAPLA-------------APPEEPAAPSP-EDPELP 1541
Query: 137 PAPSLPLS 144
L L+
Sbjct: 1542 DTRPLHLA 1549
Score = 32.7 bits (73), Expect = 0.37
Identities = 32/110 (29%), Positives = 43/110 (39%), Gaps = 15/110 (13%)
Query: 119 APPLPPPSPPPLPPPP-LPPAPSLPLSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEEV-- 175
APP P+PPP P P + P P +P+PP + LL E +E+V
Sbjct: 1691 APPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAPEKPSLLR-PVEKEKEKEKVTR 1749
Query: 176 GMPPL----------PPPQQPPPPSPPQPSRLAPYPHPATTRGDRKQKKR 215
G PL P++ P SRL P P + + KKR
Sbjct: 1750 GERPLRGERATSGRQTRPERSLATGQPATSRL-PKARPTKVKAEPPPKKR 1798
Score = 32.3 bits (72), Expect = 0.48
Identities = 40/137 (29%), Positives = 48/137 (35%), Gaps = 19/137 (13%)
Query: 20 GLGWLVDYGKLPPAPAPLAPYEVLGGALEGGLPVGGEPLAGDGFSDWMTERVDFTALLPL 79
G G DYGK P E G G P G P A D + + R
Sbjct: 955 GGGAADDYGKAGPP-------EDEGDPKAGAGPPPGPP-AYDPYGPYCPGRASGAG---- 1002
Query: 80 EPPLPPGTLPQPSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPPPLPPPPLPPAP 139
P PG P+ PP+L + + L Q PPP PPP PPP P
Sbjct: 1003 --PETPGLGLDPNK-PPELPSTVNAEPLGLIQSGPH----QAAPPPPPPPPPPPAPASEP 1055
Query: 140 SLPLSLPSFDLPQPPVL 156
L+ P F +P L
Sbjct: 1056 KGGLTSPIFCSTKPKKL 1072
Score = 30.4 bits (67), Expect = 1.8
Identities = 14/31 (45%), Positives = 15/31 (48%), Gaps = 5/31 (16%)
Query: 178 PPLPPPQQPPPPSP-----PQPSRLAPYPHP 203
PPL PP+ PP P PQP PHP
Sbjct: 1305 PPLSPPKSVPPSVPARGLQPQPPATPAVPHP 1335
Score = 29.3 bits (64), Expect = 4.1
Identities = 16/60 (26%), Positives = 26/60 (43%), Gaps = 1/60 (1%)
Query: 181 PPPQQP-PPPSPPQPSRLAPYPHPATTRGDRKQKKRDQNKSAALRYRQRKRAEGEALEGE 239
PPP+ P PPP P P + P T + K + LR ++++ + + GE
Sbjct: 1692 PPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAPEKPSLLRPVEKEKEKEKVTRGE 1751
>gi|194294554 SET binding protein 1 isoform a [Homo sapiens]
Length = 1596
Score = 63.5 bits (153), Expect = 2e-10
Identities = 47/135 (34%), Positives = 58/135 (42%), Gaps = 29/135 (21%)
Query: 83 LPPGTLPQPSPTPPDLEAMAS--LLKKELEQMEDFFLDAPPLPPPSPPPLPPPPLPPAPS 140
LP +PS +P LE AS + +E + +APPLPPP PPPLPPPP PP P
Sbjct: 1481 LPSKRGQKPSLSPLVLEPAASQDTIMATIEAVIHMAREAPPLPPPPPPPLPPPPPPPLP- 1539
Query: 141 LPLSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPPLPPPQQPPPPSPPQPSRLAPY 200
P PP+ T G + P P QPP SPPQ P
Sbjct: 1540 ----------PPPPLPKT----------PRGGKRKHKP--QAPAQPPQQSPPQ----QPL 1573
Query: 201 PHPATTRGDRKQKKR 215
P + R++K R
Sbjct: 1574 PQEEEVKAKRQRKSR 1588
Score = 32.0 bits (71), Expect = 0.63
Identities = 21/57 (36%), Positives = 24/57 (42%), Gaps = 7/57 (12%)
Query: 78 PLEPPLPPGTLPQPSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPPPLPPPP 134
P PPLPP P P P PP L K++ + AP PP PP P P
Sbjct: 1525 PPPPPLPPPP-PPPLPPPPPLPKTPRGGKRKHKP------QAPAQPPQQSPPQQPLP 1574
>gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 63.2 bits (152), Expect = 3e-10
Identities = 55/177 (31%), Positives = 68/177 (38%), Gaps = 23/177 (12%)
Query: 31 PPAPAPLAPYEVLGGALEGGLPVGGEPLAGDGFSDWMTERVDFTALLPLEPPLPPGTLPQ 90
PP PAP P ++ P GG PL L LEPP PP P
Sbjct: 143 PPGPAPGPPQDI-------SEPPGGSPLPSP------PSTAPPPPPLLLEPPPPPSMAPP 189
Query: 91 PSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPPPLP-PPPLPPAPSLPLSLPSFD 149
P P L +L + DF APPL +PPP P P P PPAP+ P ++ +
Sbjct: 190 PPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRL 249
Query: 150 LPQPPVLDTLDLLAIYCRNEAGQEEVGMPPLPPPQQPPPPSPPQPSRLAPYPHPATT 206
P V +A+ N E P P P+ P+ S L P P P T
Sbjct: 250 FPPGGVTKWKSDVAL---NGRQAEATRASP------PRSPAEPKGSALGPNPEPHLT 297
Score = 54.7 bits (130), Expect = 9e-08
Identities = 45/134 (33%), Positives = 50/134 (37%), Gaps = 25/134 (18%)
Query: 79 LEPPLPPGTLPQPSPTPPDLEAMASLLKKELEQMEDFFLDAPP--LPPPSPPPLPPPPLP 136
L PP PPG P+P PP + PP P PSPP PPP P
Sbjct: 138 LIPPPPPG----PAPGPPQ------------------DISEPPGGSPLPSPPSTAPPP-P 174
Query: 137 PAPSLPLSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPPLPPPQQPPPPSPPQPSR 196
P P PS P PPVL+ L +PP PP PP PP P+
Sbjct: 175 PLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAP 234
Query: 197 LAPYPHPATTRGDR 210
P P T G R
Sbjct: 235 APPAPASPHTVGTR 248
Score = 50.8 bits (120), Expect = 1e-06
Identities = 45/143 (31%), Positives = 56/143 (39%), Gaps = 34/143 (23%)
Query: 85 PGTLPQPSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPP-PLPPPPLPP-APSLP 142
PG L +P P L S + ++ APPLPPP+PP P P PPLPP AP LP
Sbjct: 363 PGELKATAPASPRLGQSQS----QADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLP 418
Query: 143 LSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPPLPPPQQP---PPPSPPQPSRLAP 199
C +A G P P P P+PP P A
Sbjct: 419 -----------------------CAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTAS 455
Query: 200 YPHPATTRGDRKQKKRDQNKSAA 222
P R D Q ++ +N+ AA
Sbjct: 456 -SAPVDWR-DPSQMEKLRNELAA 476
Score = 40.4 bits (93), Expect = 0.002
Identities = 41/142 (28%), Positives = 51/142 (35%), Gaps = 17/142 (11%)
Query: 78 PLEPPLPPGTLPQPSPTPPDLEAMASL--LKKELEQMEDFFLDAPPLPPPSPPPLPPPPL 135
P PPLPP P P P PP A L +K F P S P L P P
Sbjct: 391 PPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGF----TKTPKSSSPALKPKPN 446
Query: 136 PPAPSLPLSLPSFDLPQPPVLDTL--DLLAIYCRNEAGQEEVGMPPLPPPQQPPP----- 188
PP+P S D P ++ L +L A C + +E+ + P P P
Sbjct: 447 PPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSR--REDRFLSHRPGPTVAPQSKEGK 504
Query: 189 --PSPPQPSRLAPYPHPATTRG 208
P P+ L P T G
Sbjct: 505 KGPRLPEKETLLSLPAKDTPPG 526
Score = 37.0 bits (84), Expect = 0.019
Identities = 28/91 (30%), Positives = 39/91 (42%), Gaps = 8/91 (8%)
Query: 55 GEPLAGDGFSDWMTERVDFTALLPLEPP----LPPGTLPQPSPTPPDLEAMASLLKKELE 110
G L D ++ R ++T P P + P LPQ P P + S K E
Sbjct: 917 GPRLGRDAEGTELSRRHNWTKPEPQAPVAWERVAPSNLPQGHPLPKSFSSPPSPSNKREE 976
Query: 111 QMEDFFLDAPPLPPPSPPPLPPPPLPPAPSL 141
+ E+F + +PP PP P PPAP+L
Sbjct: 977 EEEEFNFEV--IPP--PPEFSNDPEPPAPAL 1003
Score = 29.3 bits (64), Expect = 4.1
Identities = 42/177 (23%), Positives = 60/177 (33%), Gaps = 27/177 (15%)
Query: 88 LPQPSPTPP------DLEA-MASLLKKELEQMEDFFLDAPPLPPPSPPPLPPPPLPPAPS 140
+PQ SPTP +LEA ++S +KE + PS LPP P
Sbjct: 554 IPQDSPTPSVRQIRNELEARLSSAAEKEAK--------------PSIGSLPPKPRLEGGR 599
Query: 141 LPLSLPSFDLPQPPVLDTLDLLAIYCRNEAG-QEEVGMPPLPPPQQPPPPSPPQPSRLAP 199
+ + D PV L + Q + + P PP+ P P+ P + L P
Sbjct: 600 ICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWP 659
Query: 200 YPHPATTRGDRKQKKRDQNKSAALRYRQRKRAEGEALEGECQGLEARNRELKERAES 256
P T G K + L K G A+ L +L +S
Sbjct: 660 ATPPKATLGPATPLKATSGPTTPL-----KATSGPAIASTATTLPTTTSQLMAEKDS 711
>gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 63.2 bits (152), Expect = 3e-10
Identities = 55/177 (31%), Positives = 68/177 (38%), Gaps = 23/177 (12%)
Query: 31 PPAPAPLAPYEVLGGALEGGLPVGGEPLAGDGFSDWMTERVDFTALLPLEPPLPPGTLPQ 90
PP PAP P ++ P GG PL L LEPP PP P
Sbjct: 143 PPGPAPGPPQDI-------SEPPGGSPLPSP------PSTAPPPPPLLLEPPPPPSMAPP 189
Query: 91 PSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPPPLP-PPPLPPAPSLPLSLPSFD 149
P P L +L + DF APPL +PPP P P P PPAP+ P ++ +
Sbjct: 190 PPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRL 249
Query: 150 LPQPPVLDTLDLLAIYCRNEAGQEEVGMPPLPPPQQPPPPSPPQPSRLAPYPHPATT 206
P V +A+ N E P P P+ P+ S L P P P T
Sbjct: 250 FPPGGVTKWKSDVAL---NGRQAEATRASP------PRSPAEPKGSALGPNPEPHLT 297
Score = 54.7 bits (130), Expect = 9e-08
Identities = 45/134 (33%), Positives = 50/134 (37%), Gaps = 25/134 (18%)
Query: 79 LEPPLPPGTLPQPSPTPPDLEAMASLLKKELEQMEDFFLDAPP--LPPPSPPPLPPPPLP 136
L PP PPG P+P PP + PP P PSPP PPP P
Sbjct: 138 LIPPPPPG----PAPGPPQ------------------DISEPPGGSPLPSPPSTAPPP-P 174
Query: 137 PAPSLPLSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPPLPPPQQPPPPSPPQPSR 196
P P PS P PPVL+ L +PP PP PP PP P+
Sbjct: 175 PLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAP 234
Query: 197 LAPYPHPATTRGDR 210
P P T G R
Sbjct: 235 APPAPASPHTVGTR 248
Score = 50.8 bits (120), Expect = 1e-06
Identities = 45/143 (31%), Positives = 56/143 (39%), Gaps = 34/143 (23%)
Query: 85 PGTLPQPSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPP-PLPPPPLPP-APSLP 142
PG L +P P L S + ++ APPLPPP+PP P P PPLPP AP LP
Sbjct: 363 PGELKATAPASPRLGQSQS----QADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLP 418
Query: 143 LSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPPLPPPQQP---PPPSPPQPSRLAP 199
C +A G P P P P+PP P A
Sbjct: 419 -----------------------CAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTAS 455
Query: 200 YPHPATTRGDRKQKKRDQNKSAA 222
P R D Q ++ +N+ AA
Sbjct: 456 -SAPVDWR-DPSQMEKLRNELAA 476
Score = 40.4 bits (93), Expect = 0.002
Identities = 41/142 (28%), Positives = 51/142 (35%), Gaps = 17/142 (11%)
Query: 78 PLEPPLPPGTLPQPSPTPPDLEAMASL--LKKELEQMEDFFLDAPPLPPPSPPPLPPPPL 135
P PPLPP P P P PP A L +K F P S P L P P
Sbjct: 391 PPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGF----TKTPKSSSPALKPKPN 446
Query: 136 PPAPSLPLSLPSFDLPQPPVLDTL--DLLAIYCRNEAGQEEVGMPPLPPPQQPPP----- 188
PP+P S D P ++ L +L A C + +E+ + P P P
Sbjct: 447 PPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSR--REDRFLSHRPGPTVAPQSKEGK 504
Query: 189 --PSPPQPSRLAPYPHPATTRG 208
P P+ L P T G
Sbjct: 505 KGPRLPEKETLLSLPAKDTPPG 526
Score = 37.0 bits (84), Expect = 0.019
Identities = 28/91 (30%), Positives = 39/91 (42%), Gaps = 8/91 (8%)
Query: 55 GEPLAGDGFSDWMTERVDFTALLPLEPP----LPPGTLPQPSPTPPDLEAMASLLKKELE 110
G L D ++ R ++T P P + P LPQ P P + S K E
Sbjct: 917 GPRLGRDAEGTELSRRHNWTKPEPQAPVAWERVAPSNLPQGHPLPKSFSSPPSPSNKREE 976
Query: 111 QMEDFFLDAPPLPPPSPPPLPPPPLPPAPSL 141
+ E+F + +PP PP P PPAP+L
Sbjct: 977 EEEEFNFEV--IPP--PPEFSNDPEPPAPAL 1003
Score = 29.3 bits (64), Expect = 4.1
Identities = 42/177 (23%), Positives = 60/177 (33%), Gaps = 27/177 (15%)
Query: 88 LPQPSPTPP------DLEA-MASLLKKELEQMEDFFLDAPPLPPPSPPPLPPPPLPPAPS 140
+PQ SPTP +LEA ++S +KE + PS LPP P
Sbjct: 554 IPQDSPTPSVRQIRNELEARLSSAAEKEAK--------------PSIGSLPPKPRLEGGR 599
Query: 141 LPLSLPSFDLPQPPVLDTLDLLAIYCRNEAG-QEEVGMPPLPPPQQPPPPSPPQPSRLAP 199
+ + D PV L + Q + + P PP+ P P+ P + L P
Sbjct: 600 ICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWP 659
Query: 200 YPHPATTRGDRKQKKRDQNKSAALRYRQRKRAEGEALEGECQGLEARNRELKERAES 256
P T G K + L K G A+ L +L +S
Sbjct: 660 ATPPKATLGPATPLKATSGPTTPL-----KATSGPAIASTATTLPTTTSQLMAEKDS 711
>gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo
sapiens]
Length = 1188
Score = 63.2 bits (152), Expect = 3e-10
Identities = 55/177 (31%), Positives = 68/177 (38%), Gaps = 23/177 (12%)
Query: 31 PPAPAPLAPYEVLGGALEGGLPVGGEPLAGDGFSDWMTERVDFTALLPLEPPLPPGTLPQ 90
PP PAP P ++ P GG PL L LEPP PP P
Sbjct: 143 PPGPAPGPPQDI-------SEPPGGSPLPSP------PSTAPPPPPLLLEPPPPPSMAPP 189
Query: 91 PSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPPPLP-PPPLPPAPSLPLSLPSFD 149
P P L +L + DF APPL +PPP P P P PPAP+ P ++ +
Sbjct: 190 PPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRL 249
Query: 150 LPQPPVLDTLDLLAIYCRNEAGQEEVGMPPLPPPQQPPPPSPPQPSRLAPYPHPATT 206
P V +A+ N E P P P+ P+ S L P P P T
Sbjct: 250 FPPGGVTKWKSDVAL---NGRQAEATRASP------PRSPAEPKGSALGPNPEPHLT 297
Score = 54.7 bits (130), Expect = 9e-08
Identities = 45/134 (33%), Positives = 50/134 (37%), Gaps = 25/134 (18%)
Query: 79 LEPPLPPGTLPQPSPTPPDLEAMASLLKKELEQMEDFFLDAPP--LPPPSPPPLPPPPLP 136
L PP PPG P+P PP + PP P PSPP PPP P
Sbjct: 138 LIPPPPPG----PAPGPPQ------------------DISEPPGGSPLPSPPSTAPPP-P 174
Query: 137 PAPSLPLSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPPLPPPQQPPPPSPPQPSR 196
P P PS P PPVL+ L +PP PP PP PP P+
Sbjct: 175 PLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAP 234
Query: 197 LAPYPHPATTRGDR 210
P P T G R
Sbjct: 235 APPAPASPHTVGTR 248
Score = 50.8 bits (120), Expect = 1e-06
Identities = 45/143 (31%), Positives = 56/143 (39%), Gaps = 34/143 (23%)
Query: 85 PGTLPQPSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPP-PLPPPPLPP-APSLP 142
PG L +P P L S + ++ APPLPPP+PP P P PPLPP AP LP
Sbjct: 363 PGELKATAPASPRLGQSQS----QADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLP 418
Query: 143 LSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPPLPPPQQP---PPPSPPQPSRLAP 199
C +A G P P P P+PP P A
Sbjct: 419 -----------------------CAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTAS 455
Query: 200 YPHPATTRGDRKQKKRDQNKSAA 222
P R D Q ++ +N+ AA
Sbjct: 456 -SAPVDWR-DPSQMEKLRNELAA 476
Score = 40.4 bits (93), Expect = 0.002
Identities = 41/142 (28%), Positives = 51/142 (35%), Gaps = 17/142 (11%)
Query: 78 PLEPPLPPGTLPQPSPTPPDLEAMASL--LKKELEQMEDFFLDAPPLPPPSPPPLPPPPL 135
P PPLPP P P P PP A L +K F P S P L P P
Sbjct: 391 PPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGF----TKTPKSSSPALKPKPN 446
Query: 136 PPAPSLPLSLPSFDLPQPPVLDTL--DLLAIYCRNEAGQEEVGMPPLPPPQQPPP----- 188
PP+P S D P ++ L +L A C + +E+ + P P P
Sbjct: 447 PPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSR--REDRFLSHRPGPTVAPQSKEGK 504
Query: 189 --PSPPQPSRLAPYPHPATTRG 208
P P+ L P T G
Sbjct: 505 KGPRLPEKETLLSLPAKDTPPG 526
Score = 37.0 bits (84), Expect = 0.019
Identities = 28/91 (30%), Positives = 39/91 (42%), Gaps = 8/91 (8%)
Query: 55 GEPLAGDGFSDWMTERVDFTALLPLEPP----LPPGTLPQPSPTPPDLEAMASLLKKELE 110
G L D ++ R ++T P P + P LPQ P P + S K E
Sbjct: 917 GPRLGRDAEGTELSRRHNWTKPEPQAPVAWERVAPSNLPQGHPLPKSFSSPPSPSNKREE 976
Query: 111 QMEDFFLDAPPLPPPSPPPLPPPPLPPAPSL 141
+ E+F + +PP PP P PPAP+L
Sbjct: 977 EEEEFNFEV--IPP--PPEFSNDPEPPAPAL 1003
Score = 29.3 bits (64), Expect = 4.1
Identities = 42/177 (23%), Positives = 60/177 (33%), Gaps = 27/177 (15%)
Query: 88 LPQPSPTPP------DLEA-MASLLKKELEQMEDFFLDAPPLPPPSPPPLPPPPLPPAPS 140
+PQ SPTP +LEA ++S +KE + PS LPP P
Sbjct: 554 IPQDSPTPSVRQIRNELEARLSSAAEKEAK--------------PSIGSLPPKPRLEGGR 599
Query: 141 LPLSLPSFDLPQPPVLDTLDLLAIYCRNEAG-QEEVGMPPLPPPQQPPPPSPPQPSRLAP 199
+ + D PV L + Q + + P PP+ P P+ P + L P
Sbjct: 600 ICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWP 659
Query: 200 YPHPATTRGDRKQKKRDQNKSAALRYRQRKRAEGEALEGECQGLEARNRELKERAES 256
P T G K + L K G A+ L +L +S
Sbjct: 660 ATPPKATLGPATPLKATSGPTTPL-----KATSGPAIASTATTLPTTTSQLMAEKDS 711
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 62.8 bits (151), Expect = 3e-10
Identities = 57/144 (39%), Positives = 62/144 (43%), Gaps = 32/144 (22%)
Query: 78 PLEPPLPPG--TLPQPSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPP---PSP----- 127
P P PP TLP P TPP +A SL L+ F L +PPL P P P
Sbjct: 303 PPSPSAPPSLQTLPSPPATPPS-QATTSLGSPTLQATHSF-LPSPPLSPLATPPPQAPPA 360
Query: 128 ---PPLPPPPLPPA--PSLPLSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPPLPP 182
PPL PP PPA P PL+ PS PQ P + LL Q PP PP
Sbjct: 361 LALPPLQAPPSPPASPPLSPLATPS---PQAPNALAVHLL---------QAPFSPPPSPP 408
Query: 183 PQQP--PPPSPP-QPSRLAPYPHP 203
Q P PP SPP PS P P
Sbjct: 409 VQAPFSPPASPPVSPSATPPSQAP 432
Score = 62.0 bits (149), Expect = 6e-10
Identities = 68/205 (33%), Positives = 76/205 (37%), Gaps = 47/205 (22%)
Query: 31 PPAPAPLAPYEVLGGALEGGLPVGGEPLAGDGFSDWMTERVDFTALLPLEPPLPPGTLPQ 90
PPA PL+P L V L FS + V P PP+ P P
Sbjct: 372 PPASPPLSPLATPSPQAPNALAVH---LLQAPFSPPPSPPVQAPFSPPASPPVSPSATP- 427
Query: 91 PSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPPPLPPPPLPPAPSLPLSLPSFDL 150
PS PP L A L PP PP SPP P PP PL+ P L
Sbjct: 428 PSQAPPSLAAPP--------------LQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQL 473
Query: 151 ----PQ-PPVLDTLDLLAIYC--RNEAGQ------EEVGMPPL--PPPQQPP-------- 187
PQ PP L T L A+ + GQ + M PL PPPQ PP
Sbjct: 474 AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQ 533
Query: 188 -PPSPP-----QPSRLAPYPHPATT 206
PPSPP Q R P P P T+
Sbjct: 534 VPPSPPASPTLQAPRRPPTPGPDTS 558
Score = 53.5 bits (127), Expect = 2e-07
Identities = 51/155 (32%), Positives = 59/155 (38%), Gaps = 34/155 (21%)
Query: 78 PLEPP---LPPGTLPQPSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPP---PLP 131
P PP LPP P P P L +A+ + + L AP PPPSPP P
Sbjct: 355 PQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFS 414
Query: 132 PPPLPPA-----------PSL---PLSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGM 177
PP PP PSL PL +P P PP + A +
Sbjct: 415 PPASPPVSPSATPPSQAPPSLAAPPLQVP----PSPPASPPMSPSA--TPPPQAPPPLAA 468
Query: 178 PPL----PPPQQPP----PPSPPQPSRLAPYPHPA 204
PPL PPPQ PP PP PS A +P A
Sbjct: 469 PPLQLAKPPPQAPPALATPPLQALPSPPASFPGQA 503
Score = 44.3 bits (103), Expect = 1e-04
Identities = 51/156 (32%), Positives = 58/156 (37%), Gaps = 48/156 (30%)
Query: 74 TALLPLEP--PLPPG--TLPQPSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSP-- 127
T P P P P G L P TPP +A +L L + PL PSP
Sbjct: 253 TPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGP----------LSSSPLATPSPSA 302
Query: 128 PPLP--PPPLPPAPSLPLSLPS---FDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPPL-- 180
PP P PP L PS P + PS L P + T L PPL
Sbjct: 303 PPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLP-------------SPPLSP 349
Query: 181 ---PPPQQPP---------PPSPPQPSRLAPYPHPA 204
PPPQ PP PPSPP L+P P+
Sbjct: 350 LATPPPQAPPALALPPLQAPPSPPASPPLSPLATPS 385
Score = 35.0 bits (79), Expect = 0.074
Identities = 54/200 (27%), Positives = 62/200 (31%), Gaps = 28/200 (14%)
Query: 34 PAPLAPYEVLGGALEGGLPVGGEP--LAGDGFSDWMTERVDFTALLPLEPP--LPPGTLP 89
P P AP + L+ P P LA + F P P LP L
Sbjct: 458 PPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLA 517
Query: 90 QPSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPP--------------PLPPPPL 135
P P P + A A LL+ L AP PP P P PPPP
Sbjct: 518 TPPPQAPPVLA-APLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPP 576
Query: 136 PPAPSLPLSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPP------LPPPQQPPPP 189
+PS LS P T + L Y G PP P P
Sbjct: 577 SRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGP 636
Query: 190 SPPQPSR---LAPYPHPATT 206
+PP R AP P P T
Sbjct: 637 APPLAFRGAPGAPLPWPPAT 656
Score = 34.7 bits (78), Expect = 0.097
Identities = 27/92 (29%), Positives = 31/92 (33%), Gaps = 12/92 (13%)
Query: 117 LDAPPLPPPSPPPLPPPPLPPAPSLPLSLPSFDLPQ--PPVLDTLDLLAIYCRNEAGQEE 174
L +P PS P P P+ P L + PQ PP D L
Sbjct: 240 LSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALG----------P 289
Query: 175 VGMPPLPPPQQPPPPSPPQPSRLAPYPHPATT 206
+ PL P PPSP P L P P T
Sbjct: 290 LSSSPLATPSPSAPPSPSAPPSLQTLPSPPAT 321
Score = 34.3 bits (77), Expect = 0.13
Identities = 37/146 (25%), Positives = 48/146 (32%), Gaps = 27/146 (18%)
Query: 74 TALLPLEPPLPPGTLPQPSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPPP---- 129
T L PP PP P + + PDL +S E++ + SPPP
Sbjct: 565 TLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAEL 624
Query: 130 --LPPPPLPPAPSLPLSL---PSFDLPQPPVLD--TLDLLAIYCRNEAGQEEVGMPPLPP 182
P P+ PL+ P LP PP + D L E
Sbjct: 625 AACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEG------------ 672
Query: 183 PQQPPPPSPPQPSRLAPYPHPATTRG 208
P + P P L P P P T+ G
Sbjct: 673 ----PESATPAPGALDPGPSPGTSGG 694
Score = 28.9 bits (63), Expect = 5.3
Identities = 25/92 (27%), Positives = 32/92 (34%), Gaps = 19/92 (20%)
Query: 119 APPLPPPSPPPLPPPPLPPAPSLPLSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMP 178
AP L P PP P PP P P+ L L R + G+
Sbjct: 21 APGLLTPRPPGSPRPPPPVTPA--------------ALRVLGAAGAVGRKPLAERAGGIG 66
Query: 179 PLPPPQQPPPPSPPQPSRLAPYPHPATTRGDR 210
P+ P P + SR PA+ RG+R
Sbjct: 67 GATIPESAPRAGPTRTSR-----PPASGRGER 93
>gi|126090663 zinc finger homeodomain 4 [Homo sapiens]
Length = 3571
Score = 62.4 bits (150), Expect = 4e-10
Identities = 33/96 (34%), Positives = 43/96 (44%), Gaps = 10/96 (10%)
Query: 100 AMASLLKKELEQMEDFFLDAPPLPPPSPPPLPPPPLPPAPSLPLSLPSFDLPQPPVLDTL 159
A+ ++ E + + +P P PPP PPPPLPPAP P S+ +P
Sbjct: 1932 ALEKFARQYREAYDKLYPISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPN------- 1984
Query: 160 DLLAIYCRNEAGQEEVGMPPLPPPQQPPPPSPPQPS 195
+ +A PP PPP PPPP PP PS
Sbjct: 1985 ---TVSTPLQAPPPTPPPPPPPPPPPPPPPPPPPPS 2017
Score = 57.4 bits (137), Expect = 1e-08
Identities = 33/85 (38%), Positives = 40/85 (47%), Gaps = 3/85 (3%)
Query: 70 RVDFTALLPLEPPLP--PGTLPQPSPTPPDLEAMASLLKKELEQMEDFFLDAPP-LPPPS 126
R + L P+ P P P P P P PP +S+ ++ L APP PPP
Sbjct: 1941 REAYDKLYPISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPP 2000
Query: 127 PPPLPPPPLPPAPSLPLSLPSFDLP 151
PPP PPPP PP P P + P LP
Sbjct: 2001 PPPPPPPPPPPPPPPPSAPPQVQLP 2025
Score = 40.0 bits (92), Expect = 0.002
Identities = 16/28 (57%), Positives = 18/28 (64%)
Query: 178 PPLPPPQQPPPPSPPQPSRLAPYPHPAT 205
PP PPP P PP+PPQPS + P P T
Sbjct: 1958 PPPPPPPPPLPPAPPQPSSMGPVKIPNT 1985
Score = 38.5 bits (88), Expect = 0.007
Identities = 35/108 (32%), Positives = 42/108 (38%), Gaps = 14/108 (12%)
Query: 124 PPSPPPLP--PPPLPPAPSLPLSLPSFDLPQ------PPVLDTLDLLAIYCRNEA-GQEE 174
P + P LP PP L P + P SLP F PQ PP L + A
Sbjct: 3050 PTAYPGLPGLPPVLLPGMNGPSSLPGF--PQNSNTLTPPGAGMLGFPTSATSSPALSLSS 3107
Query: 175 VGMPPL---PPPQQPPPPSPPQPSRLAPYPHPATTRGDRKQKKRDQNK 219
PL PPP PPPP PP S ++KQ K ++ K
Sbjct: 3108 APTKPLLQTPPPPPPPPPPPPSSSLSGQQTEQQNKESEKKQTKPNKVK 3155
Score = 37.4 bits (85), Expect = 0.015
Identities = 32/102 (31%), Positives = 36/102 (35%), Gaps = 35/102 (34%)
Query: 78 PLEPPLPPGTLPQPSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPPPLPPPP--- 134
P PPLPP PQPS P + + + L+ PP PPP PPP PPPP
Sbjct: 1962 PPPPPLPPAP-PQPSSMGP--VKIPNTVSTPLQAPPPTPPPPPPPPPPPPPPPPPPPPSA 2018
Query: 135 ---------------------------LPPAPSLPLSLPSFD 149
LPP L L LP D
Sbjct: 2019 PPQVQLPVSLDLPLFPSIMMQPVQHPALPPQ--LALQLPQMD 2058
Score = 34.3 bits (77), Expect = 0.13
Identities = 25/86 (29%), Positives = 30/86 (34%), Gaps = 8/86 (9%)
Query: 120 PPLPPPSPPPLPPPPLPPAPSLPLSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPP 179
P +P P P P P P P P P PP T L + + + P
Sbjct: 2345 PLIPSPKP---EPEKTSPKPEYPAEKPKQSDPSPPSQGTKPALPLASTSSDPPQASTAQP 2401
Query: 180 LPPPQQPPPPS----PPQPSRLAPYP 201
P PQ P P PP S+ P P
Sbjct: 2402 QPQPQPPKQPQLIGRPPSASQ-TPVP 2426
Score = 32.7 bits (73), Expect = 0.37
Identities = 15/26 (57%), Positives = 15/26 (57%)
Query: 119 APPLPPPSPPPLPPPPLPPAPSLPLS 144
AP P PP PPPP PP PS LS
Sbjct: 3108 APTKPLLQTPPPPPPPPPPPPSSSLS 3133
Score = 28.9 bits (63), Expect = 5.3
Identities = 18/52 (34%), Positives = 20/52 (38%), Gaps = 4/52 (7%)
Query: 84 PPGTLPQPSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPPPLPPPPL 135
PPG PT SL + + L PP PPP PPP P L
Sbjct: 3085 PPGAGMLGFPTSATSSPALSLSSAPTKPL----LQTPPPPPPPPPPPPSSSL 3132
>gi|157168329 formin 1 [Homo sapiens]
Length = 1196
Score = 62.0 bits (149), Expect = 6e-10
Identities = 46/129 (35%), Positives = 53/129 (41%), Gaps = 47/129 (36%)
Query: 82 PLPPGTLPQPSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSP-PPLPPPPLPPAPS 140
P PP ++P P P P L +++ APP+PP S PPLPPPP PP P
Sbjct: 646 PPPPASIPPPPPLPSGLGSLSP---------------APPMPPVSAGPPLPPPP-PPPP- 688
Query: 141 LPLSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPPLPPPQQPPPPSP------PQP 194
PL PS P PP PP P P P PP+P P P
Sbjct: 689 -PLPPPSSAGPPPP----------------------PPPPPLPNSPAPPNPGGPPPAPPP 725
Query: 195 SRLAPYPHP 203
LAP P P
Sbjct: 726 PGLAPPPPP 734
Score = 42.0 bits (97), Expect = 6e-04
Identities = 42/147 (28%), Positives = 46/147 (31%), Gaps = 36/147 (24%)
Query: 10 ELDRALLPASGLGWLVDYGKLPPAPAPLAPYEVLGGALEGGLPVGGEPLAGDGFSDWMTE 69
++ AL P G+ LPP PA + P L L P P G
Sbjct: 626 DIHAALQPMEGMA-SNQQKALPPPPASIPPPPPLPSGLGSLSPAPPMPPVSAG------- 677
Query: 70 RVDFTALLPLEPPLPPGTLPQPSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPPP 129
PPLPP P P P PP A PP PPP P
Sbjct: 678 -----------PPLPPPP-PPPPPLPPPSSAGPP----------------PPPPPPPLPN 709
Query: 130 LPPPPLPPAPSLPLSLPSFDLPQPPVL 156
P PP P P P P PP L
Sbjct: 710 SPAPPNPGGPPPAPPPPGLAPPPPPGL 736
Score = 33.9 bits (76), Expect = 0.16
Identities = 27/77 (35%), Positives = 29/77 (37%), Gaps = 27/77 (35%)
Query: 130 LPPPP--LPPAPSLPLSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPPLPPPQQPP 187
LPPPP +PP P LP L S P PP MPP+ PP
Sbjct: 645 LPPPPASIPPPPPLPSGLGSLS-PAPP----------------------MPPVSAG--PP 679
Query: 188 PPSPPQPSRLAPYPHPA 204
P PP P P P A
Sbjct: 680 LPPPPPPPPPLPPPSSA 696
>gi|33356148 formin-like 1 [Homo sapiens]
Length = 1100
Score = 61.6 bits (148), Expect = 7e-10
Identities = 40/113 (35%), Positives = 45/113 (39%), Gaps = 25/113 (22%)
Query: 81 PPLPPGTLPQPSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPPPLP-PPPLPPAP 139
P L P P P PP + L + +APP PP PPLP P PPAP
Sbjct: 528 PDLAPAAEPAPGAAPPPPPPLPGLPSPQ---------EAPPSAPPQAPPLPGSPEPPPAP 578
Query: 140 SLPLSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPPLPPPQQPPPPSPP 192
LP LP P PP T + +PP PPP PPP PP
Sbjct: 579 PLPGDLPPPPPPPPPPPGT---------------DGPVPPPPPPPPPPPGGPP 616
Score = 44.3 bits (103), Expect = 1e-04
Identities = 36/114 (31%), Positives = 39/114 (34%), Gaps = 40/114 (35%)
Query: 28 GKLPPAPAPL----APYEVLGGALEGGLPVGGEPLAGDGFSDWMTERVDFTALLPLEPPL 83
G PP P PL +P E A P+ G P P PPL
Sbjct: 539 GAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPGSPEP------------------PPAPPL 580
Query: 84 PPGTLPQPSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPPPLPPPPLPP 137
P G LP P P PP P+PPP PPP PPP PP
Sbjct: 581 P-GDLPPPPPPPPPPPGTDG-----------------PVPPPPPPPPPPPGGPP 616
Score = 43.5 bits (101), Expect = 2e-04
Identities = 43/143 (30%), Positives = 54/143 (37%), Gaps = 40/143 (27%)
Query: 89 PQPSPTPPDLEAMASLLKKELEQMEDFFL--------DAPPLPP-PSPPPLPPPPLPPAP 139
P+P PP S L+ ++E++E+ L DA + P P P P
Sbjct: 460 PEPEKAPPAAPTRPSALELKVEELEEKGLIRILRGPGDAVSIEILPVAVATPSGGDAPTP 519
Query: 140 SLPLSLPSFDL------------PQPPVLDTLDLLAIYCRNEAGQEEVGMPPLPPPQQPP 187
+P PS DL P PP L L + QE PP PPQ PP
Sbjct: 520 GVPTGSPSPDLAPAAEPAPGAAPPPPPPLPGLP---------SPQEA---PPSAPPQAPP 567
Query: 188 -------PPSPPQPSRLAPYPHP 203
PP+PP P L P P P
Sbjct: 568 LPGSPEPPPAPPLPGDLPPPPPP 590
Score = 32.0 bits (71), Expect = 0.63
Identities = 14/29 (48%), Positives = 17/29 (58%), Gaps = 1/29 (3%)
Query: 168 NEAGQ-EEVGMPPLPPPQQPPPPSPPQPS 195
N AG E+ P PPP+QP PP P P+
Sbjct: 3 NAAGSAEQPAGPAAPPPKQPAPPKQPMPA 31
>gi|60460889 Myb protein P42POP [Homo sapiens]
Length = 399
Score = 60.8 bits (146), Expect = 1e-09
Identities = 42/106 (39%), Positives = 49/106 (46%), Gaps = 21/106 (19%)
Query: 119 APPLPPPSP-------PPLPPPPLPPAPSLPLSLPSFDL--PQPPVLDTLDLLAIYCR-- 167
APPLPPP P PP PPPP P P+L S PS D Q + + LA R
Sbjct: 224 APPLPPPPPLAQVAPSPPSPPPPPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQG 283
Query: 168 ----NEAGQEEVGMPP------LPPPQQPPPPSPPQPSRLAPYPHP 203
+EA + + P LPPP PPPP PP P + P P P
Sbjct: 284 LAKLSEALSALLPLLPGTPVDSLPPPLPPPPPPPPPPRPVLPPPAP 329
Score = 58.5 bits (140), Expect = 6e-09
Identities = 45/142 (31%), Positives = 58/142 (40%), Gaps = 23/142 (16%)
Query: 78 PLEPPLPPGTLPQPSPTPPDLEA----------MASLLKKELEQMEDFFLDAPPLPPPSP 127
P PP PP TL P+ L A +A L++ L ++ + PL P +P
Sbjct: 243 PPPPPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALSALLPLLPGTP 302
Query: 128 --------PPLPPPPLPPAPSLPLSLPSFDLPQPP---VLDTLDLLAIYCRNE--AGQEE 174
PP PPPP PP P LP P ++ P V +D + R A + E
Sbjct: 303 VDSLPPPLPPPPPPPPPPRPVLPPPAPKVEITPEPVSVVAAVVDGAVVAARGVIIAPRSE 362
Query: 175 VGMPPLPPPQQPPPPSPPQPSR 196
G P PP PP SPP R
Sbjct: 363 EGAPRPPPAPLPPHDSPPHKRR 384
Score = 35.0 bits (79), Expect = 0.074
Identities = 50/207 (24%), Positives = 64/207 (30%), Gaps = 45/207 (21%)
Query: 54 GGEPLAGDGFSDWMTERVDFTALLP-----------LEPPLPPGTLPQPSPTPPDLEAMA 102
G P A D FS E F L P EPP P + P P P ++
Sbjct: 100 GAGPAAEDAFS--AEEETIFAILGPGVAAPGAGAGAEEPPAAPSSQPPPPSACPQRYVLS 157
Query: 103 SLLKKELEQMEDFFLDAPPLPP-----PS--------PPPLPPPPLPPAPSLPLSLPSFD 149
+++ A P PS P P PP+ P+ LP
Sbjct: 158 EDRREDRRADTSAHSKAGSSSPEPWARPSCTPQEGGCPRPKERESPPPSALQPVQLPRLA 217
Query: 150 LPQPPVLDTLDLLAIYCRNEAGQEEVGMPPL----PPPQQPPPPSPPQPSRLAPYPHPAT 205
L PP L PPL P P PPPP P P+ A P
Sbjct: 218 LSPPPPAPPLP---------------PPPPLAQVAPSPPSPPPPPRPPPTLSASDPSLDF 262
Query: 206 TRGDRKQKKRDQNKSAALRYRQRKRAE 232
R ++ + + LR K +E
Sbjct: 263 LRAQQETANAIRELAGTLRQGLAKLSE 289
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 60.5 bits (145), Expect = 2e-09
Identities = 64/207 (30%), Positives = 71/207 (34%), Gaps = 73/207 (35%)
Query: 17 PASGLGWLVDYGKLPPAP-APLAPYEVLGGALEGGLPVGGEPLAGDGFSDWMTERVDFTA 75
P G G L LPP P A + P L GA P PL G G
Sbjct: 925 PLPGAGIL----PLPPLPGAGIPPPPPLPGAAIPPPP----PLPGAG------------- 963
Query: 76 LLPLEPPLPPGTLPQPSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPP------PSPPP 129
+PL PPLP +P P P P PP PP P PPP
Sbjct: 964 -IPLPPPLPGAGIPPPPPLPG--------------------AGIPPPPPLPGAGIPPPPP 1002
Query: 130 LPPPPLPPAPSLPLS-------LPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPPLPP 182
LP +PP P LP + LP +P PP L G+PP PP
Sbjct: 1003 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL----------------PGAGIPPPPP 1046
Query: 183 -PQQPPPPSPPQPSRLAPYPHPATTRG 208
P PP PP P P P P G
Sbjct: 1047 LPGAGIPPPPPLPGAGIPPPPPLPGAG 1073
Score = 59.7 bits (143), Expect = 3e-09
Identities = 59/190 (31%), Positives = 67/190 (35%), Gaps = 71/190 (37%)
Query: 31 PPAPAP---LAPYEVLGGALEGGLPVGGEPLAGDGFSDWMTERVDFTALLPLEPPLPPGT 87
PP P P + P L GA G+P PL G G +P PPLP
Sbjct: 1043 PPPPLPGAGIPPPPPLPGA---GIPPP-PPLPGAG--------------IPPPPPLPGAG 1084
Query: 88 LPQPSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPP------PSPPPLPPPPLPPAPSL 141
+P P P P PP PP P PPPLP +PP P L
Sbjct: 1085 IPPPPPLPG--------------------AGIPPPPPLPGVGIPPPPPLPGAGIPPPPPL 1124
Query: 142 PLS-------LPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPPLPP-PQQPPPPSPPQ 193
P + LP +P PP L VG+PP PP P PP PP
Sbjct: 1125 PGAGIPPPPPLPGAGIPPPPPL----------------PRVGIPPPPPLPGAGIPPPPPL 1168
Query: 194 PSRLAPYPHP 203
P P P P
Sbjct: 1169 PGAGIPPPPP 1178
Score = 58.5 bits (140), Expect = 6e-09
Identities = 63/192 (32%), Positives = 67/192 (34%), Gaps = 58/192 (30%)
Query: 28 GKLPPAPAPLAPYEVLGGALEGGLPVGGEPLAGDGFSDWMTERVDFTALLPLEPPLPPGT 87
G +PP P PL V L PL G TE L P PPLP
Sbjct: 874 GMVPPPPPPLPGMTV--PTLPSTAIPQPPPLQG-------TEM-----LPPPPPPLPGAG 919
Query: 88 LPQPSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPP---PSPPPL------PPPPLPPA 138
+P P P P L PPLP P PPPL PPPPLP A
Sbjct: 920 IPPPPPLP-----------------GAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGA 962
Query: 139 P-SLPLSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPPLPP-PQQPPPPSPPQPSR 196
LP LP +P PP L G+PP PP P PP PP P
Sbjct: 963 GIPLPPPLPGAGIPPPPPL----------------PGAGIPPPPPLPGAGIPPPPPLPGA 1006
Query: 197 LAPYPHPATTRG 208
P P P G
Sbjct: 1007 GIPPPPPLPGAG 1018
Score = 58.2 bits (139), Expect = 8e-09
Identities = 59/195 (30%), Positives = 68/195 (34%), Gaps = 71/195 (36%)
Query: 31 PPAPAP---LAPYEVLGGALEGGLPVGGEPLAGDGFSDWMTERVDFTALLPLEPPLPPGT 87
PP P P + P L GA G+P PL G G +P PPLP
Sbjct: 1032 PPPPLPGAGIPPPPPLPGA---GIPPP-PPLPGAG--------------IPPPPPLPGAG 1073
Query: 88 LPQPSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPP------PSPPPLPPPPLPPAPSL 141
+P P P P PP PP P PPPLP +PP P L
Sbjct: 1074 IPPPPPLPG--------------------AGIPPPPPLPGAGIPPPPPLPGVGIPPPPPL 1113
Query: 142 PLS-------LPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPPLPP-PQQPPPPSPPQ 193
P + LP +P PP L G+PP PP P+ PP PP
Sbjct: 1114 PGAGIPPPPPLPGAGIPPPPPLPG----------------AGIPPPPPLPRVGIPPPPPL 1157
Query: 194 PSRLAPYPHPATTRG 208
P P P P G
Sbjct: 1158 PGAGIPPPPPLPGAG 1172
Score = 58.2 bits (139), Expect = 8e-09
Identities = 60/195 (30%), Positives = 68/195 (34%), Gaps = 71/195 (36%)
Query: 31 PPAPAP---LAPYEVLGGALEGGLPVGGEPLAGDGFSDWMTERVDFTALLPLEPPLPPGT 87
PP P P + P L GA G+P PL G G +P PPLP
Sbjct: 1076 PPPPLPGAGIPPPPPLPGA---GIPPP-PPLPGVG--------------IPPPPPLPGAG 1117
Query: 88 LPQPSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPP------PSPPPLPPPPLPPAPSL 141
+P P P P PP PP P PPPLP +PP P L
Sbjct: 1118 IPPPPPLPG--------------------AGIPPPPPLPGAGIPPPPPLPRVGIPPPPPL 1157
Query: 142 PLS-------LPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPPLPP-PQQPPPPSPPQ 193
P + LP +P PP L VG+PP PP P PP PP
Sbjct: 1158 PGAGIPPPPPLPGAGIPPPPPLPG----------------VGIPPPPPLPGVGIPPPPPL 1201
Query: 194 PSRLAPYPHPATTRG 208
P P P P G
Sbjct: 1202 PGAGIPPPPPLPGMG 1216
Score = 57.8 bits (138), Expect = 1e-08
Identities = 56/189 (29%), Positives = 67/189 (35%), Gaps = 59/189 (31%)
Query: 31 PPAPAP---LAPYEVLGGALEGGLPVGGEPLAGDGFSDWMTERVDFTALLPLEPPLPPGT 87
PP P P + P L GA G+P PL G G +P PPLP
Sbjct: 1098 PPPPLPGVGIPPPPPLPGA---GIPPP-PPLPGAG--------------IPPPPPLPGAG 1139
Query: 88 LPQPSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPP------PSPPPLPPPPLPPAPSL 141
+P P P P + PP PP P PPPLP +PP P L
Sbjct: 1140 IPPPPPLPR--------------------VGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1179
Query: 142 P-------LSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPPLPPPQQPPPPSPPQP 194
P LP +P PP L + +G+PP P P PPP + P
Sbjct: 1180 PGVGIPPPPPLPGVGIPPPPPLPGAGIPP-----PPPLPGMGIPPAPAPPLPPPGTGIPP 1234
Query: 195 SRLAPYPHP 203
L P P
Sbjct: 1235 PPLLPVSGP 1243
Score = 57.0 bits (136), Expect = 2e-08
Identities = 52/146 (35%), Positives = 59/146 (40%), Gaps = 25/146 (17%)
Query: 77 LPLEPPLPPGTLPQPSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPPPL------ 130
L + PP PP P P T P L + A L+ E + PP PPPL
Sbjct: 873 LGMVPPPPP---PLPGMTVPTLPSTAIPQPPPLQGTE--------MLPPPPPPLPGAGIP 921
Query: 131 PPPPLPPAPSLPL-SLPSFDLPQPPVLDTLDLLAIYCRNEAG------QEEVGMPPLPP- 182
PPPPLP A LPL LP +P PP L + AG G+PP PP
Sbjct: 922 PPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPL 981
Query: 183 PQQPPPPSPPQPSRLAPYPHPATTRG 208
P PP PP P P P P G
Sbjct: 982 PGAGIPPPPPLPGAGIPPPPPLPGAG 1007
Score = 57.0 bits (136), Expect = 2e-08
Identities = 55/176 (31%), Positives = 66/176 (37%), Gaps = 55/176 (31%)
Query: 31 PPAPAP---LAPYEVLGGALEGGLPVGGEPLAGDGFSDWMTERVDFTALLPLEPPLPPGT 87
PP P P + P L GA G+P PL G G +P PPLP
Sbjct: 1142 PPPPLPRVGIPPPPPLPGA---GIPPP-PPLPGAG--------------IPPPPPLPGVG 1183
Query: 88 LPQPSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPP------PSPPPLPPPPLPPAPSL 141
+P P P P + PP PP P PPPLP +PPAP+
Sbjct: 1184 IPPPPPLPG--------------------VGIPPPPPLPGAGIPPPPPLPGMGIPPAPAP 1223
Query: 142 PLSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPPLPPPQQPPPPSPPQPSRL 197
PL P +P PP+L + +VG LP PQ PP PS L
Sbjct: 1224 PLPPPGTGIPPPPLLPVSGPPLL--------PQVGSSTLPTPQVCGFLPPPLPSGL 1271
Score = 53.1 bits (126), Expect = 3e-07
Identities = 49/161 (30%), Positives = 62/161 (38%), Gaps = 38/161 (23%)
Query: 80 EPPLPPGTL-----PQPSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPPPLP--- 131
+PP PP L QP PP + E + F ++ +P SPPPLP
Sbjct: 809 QPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHE-HSVSSAFKNSCNIP--SPPPLPCTE 865
Query: 132 -----------PPPLPPAPSLPL-SLPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPP 179
PPP PP P + + +LPS +PQPP L ++L G G+PP
Sbjct: 866 SSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPG---AGIPP 922
Query: 180 LPP------------PQQPPPPSPPQPSRLAPYPHPATTRG 208
PP P PP PP P P P P G
Sbjct: 923 PPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAG 963
Score = 28.9 bits (63), Expect = 5.3
Identities = 63/231 (27%), Positives = 73/231 (31%), Gaps = 50/231 (21%)
Query: 9 LELDRALL-PASGLGWLVD-------YGKLPPAPAPLA--PYEVLGGALEGGLPVGGEPL 58
L LDR LL P+ G G L P LA P E GGLPV P
Sbjct: 247 LGLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSEAP- 305
Query: 59 AGDGFSDWMTERVDFTALLPLEPPLPPGT-LPQPSPTPPDLEAMASLL---KKELEQMED 114
A P P T P P P + A A + + E ED
Sbjct: 306 -------------SLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDEEGEED 352
Query: 115 FFLDAPPLPP----------PSPPPLPPPPLPPA--PSLPL--SLPSFDLPQPPVLDTLD 160
F DAP P +P L P A P P SLP P
Sbjct: 353 AFEDAPRGSPGEEWAPEVGEDAPQRLGEEPEEEAQGPDAPAAASLPGSPAPSQRCFKPYP 412
Query: 161 LLA-IYCRNEAGQEEVGMPPLPPPQQPPPPSPPQPSRLAPYPHPATTRGDR 210
L+ Y + Q L P P SP Q R+ P P+ +RG R
Sbjct: 413 LITPCYIKTTTRQ-------LSSPNHSPSQSPNQSPRIKRRPEPSLSRGSR 456
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 60.1 bits (144), Expect = 2e-09
Identities = 62/202 (30%), Positives = 73/202 (36%), Gaps = 75/202 (37%)
Query: 31 PPAPAPLAPYEVLGG-------ALEGGLPVGGEP-LAGDGFSDWMTERVDFTALLPLEPP 82
PP P P P + GG +L GG + P L+GD A +P PP
Sbjct: 601 PPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGD-------------ATIPPPPP 647
Query: 83 LPPGT-LPQPS--------PTPPDLEAMASLLKKELEQMEDFFLDAPPLP-----PPSPP 128
LP G +P PS P PP L A + PPLP PP PP
Sbjct: 648 LPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPP-----------PPLPGSAGIPPPPP 696
Query: 129 PLP--------PPPLPPAPSLPLSLP---SFDLPQPPVLDTLDLLAIYCRNEAGQEEVGM 177
PLP PPPLP P +P P +P PP +GM
Sbjct: 697 PLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPP------------------PGMGM 738
Query: 178 PPLPPPQQPPPPSPPQPSRLAP 199
PP PP P +P P L P
Sbjct: 739 PPPPPFGFGVPAAPVLPFGLTP 760
Score = 53.5 bits (127), Expect = 2e-07
Identities = 46/150 (30%), Positives = 52/150 (34%), Gaps = 34/150 (22%)
Query: 75 ALLPLEPPLP--PGTLPQPSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPPPLPP 132
A +P PPLP GT+ P P P D PP PPP PPP PP
Sbjct: 571 APVPPAPPLPGDSGTIIPPPPAPGDSTT-------------------PPPPPPPPPPPPP 611
Query: 133 PPLPPAPSLPLSLP-------------SFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPP 179
P S P SLP +P PP L + G PP
Sbjct: 612 LPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPP 671
Query: 180 LPPPQQPPPPSPPQPSRLAPYPHPATTRGD 209
LP + PPP PP P P P G+
Sbjct: 672 LPGSARIPPPPPPLPGSAGIPPPPPPLPGE 701
Score = 47.4 bits (111), Expect = 1e-05
Identities = 51/160 (31%), Positives = 56/160 (35%), Gaps = 57/160 (35%)
Query: 79 LEPPLPPG--TLPQPSPTPPDLEAMASLLKKELEQMEDFFLDAPPLP-------PPS--- 126
+ PP PG T P P P PP PPLP PPS
Sbjct: 587 IPPPPAPGDSTTPPPPPPPPP--------------------PPPPLPGGVCISSPPSLPG 626
Query: 127 ------PPPL-------PPPPLPPAPSL--PLSLP-SFDLPQPPVLDTLDLLAIYCRNEA 170
PPPL PPPPLP + P SLP +P PP L +
Sbjct: 627 GTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLP 686
Query: 171 GQEEVGMPPLPPP-------QQPPPPSPPQPSRLAPYPHP 203
G G+PP PPP PPPP P P P P P
Sbjct: 687 G--SAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFP 724
Score = 42.4 bits (98), Expect = 5e-04
Identities = 35/106 (33%), Positives = 41/106 (38%), Gaps = 30/106 (28%)
Query: 97 DLEAMASLLK-------KELE----QMEDFFLDAPPLPPPSPPPLPPPPLPPAPSLPLSL 145
DLEA S L KELE +M A +PP P P PP PP P ++
Sbjct: 527 DLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTI 586
Query: 146 PSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPPLPPPQQPPPPSP 191
+P PP A + PP PPP PPPP P
Sbjct: 587 ----IPPPP---------------APGDSTTPPPPPPPPPPPPPLP 613
Score = 28.1 bits (61), Expect = 9.0
Identities = 12/35 (34%), Positives = 16/35 (45%)
Query: 175 VGMPPLPPPQQPPPPSPPQPSRLAPYPHPATTRGD 209
+ +PP P + P PP+PP P P GD
Sbjct: 561 ITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGD 595
>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
Length = 1272
Score = 60.1 bits (144), Expect = 2e-09
Identities = 62/202 (30%), Positives = 73/202 (36%), Gaps = 75/202 (37%)
Query: 31 PPAPAPLAPYEVLGG-------ALEGGLPVGGEP-LAGDGFSDWMTERVDFTALLPLEPP 82
PP P P P + GG +L GG + P L+GD A +P PP
Sbjct: 610 PPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGD-------------ATIPPPPP 656
Query: 83 LPPGT-LPQPS--------PTPPDLEAMASLLKKELEQMEDFFLDAPPLP-----PPSPP 128
LP G +P PS P PP L A + PPLP PP PP
Sbjct: 657 LPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPP-----------PPLPGSAGIPPPPP 705
Query: 129 PLP--------PPPLPPAPSLPLSLP---SFDLPQPPVLDTLDLLAIYCRNEAGQEEVGM 177
PLP PPPLP P +P P +P PP +GM
Sbjct: 706 PLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPP------------------PGMGM 747
Query: 178 PPLPPPQQPPPPSPPQPSRLAP 199
PP PP P +P P L P
Sbjct: 748 PPPPPFGFGVPAAPVLPFGLTP 769
Score = 53.5 bits (127), Expect = 2e-07
Identities = 46/150 (30%), Positives = 52/150 (34%), Gaps = 34/150 (22%)
Query: 75 ALLPLEPPLP--PGTLPQPSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPPPLPP 132
A +P PPLP GT+ P P P D PP PPP PPP PP
Sbjct: 580 APVPPAPPLPGDSGTIIPPPPAPGDSTT-------------------PPPPPPPPPPPPP 620
Query: 133 PPLPPAPSLPLSLP-------------SFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPP 179
P S P SLP +P PP L + G PP
Sbjct: 621 LPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPP 680
Query: 180 LPPPQQPPPPSPPQPSRLAPYPHPATTRGD 209
LP + PPP PP P P P G+
Sbjct: 681 LPGSARIPPPPPPLPGSAGIPPPPPPLPGE 710
Score = 47.4 bits (111), Expect = 1e-05
Identities = 51/160 (31%), Positives = 56/160 (35%), Gaps = 57/160 (35%)
Query: 79 LEPPLPPG--TLPQPSPTPPDLEAMASLLKKELEQMEDFFLDAPPLP-------PPS--- 126
+ PP PG T P P P PP PPLP PPS
Sbjct: 596 IPPPPAPGDSTTPPPPPPPPP--------------------PPPPLPGGVCISSPPSLPG 635
Query: 127 ------PPPL-------PPPPLPPAPSL--PLSLP-SFDLPQPPVLDTLDLLAIYCRNEA 170
PPPL PPPPLP + P SLP +P PP L +
Sbjct: 636 GTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLP 695
Query: 171 GQEEVGMPPLPPP-------QQPPPPSPPQPSRLAPYPHP 203
G G+PP PPP PPPP P P P P P
Sbjct: 696 G--SAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFP 733
Score = 42.4 bits (98), Expect = 5e-04
Identities = 35/106 (33%), Positives = 41/106 (38%), Gaps = 30/106 (28%)
Query: 97 DLEAMASLLK-------KELE----QMEDFFLDAPPLPPPSPPPLPPPPLPPAPSLPLSL 145
DLEA S L KELE +M A +PP P P PP PP P ++
Sbjct: 536 DLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTI 595
Query: 146 PSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPPLPPPQQPPPPSP 191
+P PP A + PP PPP PPPP P
Sbjct: 596 ----IPPPP---------------APGDSTTPPPPPPPPPPPPPLP 622
Score = 28.1 bits (61), Expect = 9.0
Identities = 12/35 (34%), Positives = 16/35 (45%)
Query: 175 VGMPPLPPPQQPPPPSPPQPSRLAPYPHPATTRGD 209
+ +PP P + P PP+PP P P GD
Sbjct: 570 ITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGD 604
>gi|52485606 formin-like 2 [Homo sapiens]
Length = 1092
Score = 59.7 bits (143), Expect = 3e-09
Identities = 50/158 (31%), Positives = 60/158 (37%), Gaps = 47/158 (29%)
Query: 42 VLGGALEGGLPVGGEPLAGDGFSDWMTERVDFTALLPLEPPLPPGTLPQPSPTPPDLEAM 101
+L G L +G E +AG+ M + PL PP PP LP S TP ++
Sbjct: 493 ILPVVASGTLSMGSEVVAGNSVGPTMGA----ASSGPLPPPPPP--LPPSSDTPETVQNG 546
Query: 102 ASLLKKELEQMEDFFLDAPPLPPPSPPPLPPPPLPPAPSLPLSLPSFDLPQPPVLDTLDL 161
PP+PPP PPP PPPP PP P P LP P
Sbjct: 547 PV---------------TPPMPPPPPPPPPPPPPPPPPPPP------PLPGPAA------ 579
Query: 162 LAIYCRNEAGQEEVGMPPLPPPQQPPPPSPPQPSRLAP 199
E V PPL PP P +PP P +P
Sbjct: 580 -----------ETVPAPPLAPPL---PSAPPLPGTSSP 603
Score = 49.7 bits (117), Expect = 3e-06
Identities = 32/84 (38%), Positives = 34/84 (40%), Gaps = 24/84 (28%)
Query: 120 PPLPPPSPPPLPPPPLPPAPSLPLSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPP 179
P + S PLPPPP PP P PS D P E Q PP
Sbjct: 516 PTMGAASSGPLPPPP-PPLP------PSSDTP-----------------ETVQNGPVTPP 551
Query: 180 LPPPQQPPPPSPPQPSRLAPYPHP 203
+PPP PPPP PP P P P P
Sbjct: 552 MPPPPPPPPPPPPPPPPPPPPPLP 575
Score = 49.7 bits (117), Expect = 3e-06
Identities = 38/129 (29%), Positives = 44/129 (34%), Gaps = 55/129 (42%)
Query: 28 GKLPPAPAPLAPYEVLGGALEGGLPVGGEPLAGDGFSDWMTERVDFTALLPLEPPLPPGT 87
G LPP P PL P ++ G P+ PP+PP
Sbjct: 524 GPLPPPPPPLPPSSDTPETVQNG---------------------------PVTPPMPP-- 554
Query: 88 LPQPSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPPPLPPPPLPPAPSLPLSLPS 147
P P P PP PP PPP PPPLP P P+ PL+ P
Sbjct: 555 -PPPPPPPP----------------------PPPPPPPPPPPLPGPAAETVPAPPLAPP- 590
Query: 148 FDLPQPPVL 156
LP P L
Sbjct: 591 --LPSAPPL 597
Score = 46.2 bits (108), Expect = 3e-05
Identities = 27/78 (34%), Positives = 32/78 (41%), Gaps = 24/78 (30%)
Query: 127 PPPLPPPPLPPAPSLPLSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPPLPPPQQP 186
P P PPPPLPP+ P ++ + + P PP PPP P
Sbjct: 525 PLPPPPPPLPPSSDTPETVQNGPVTPPMP----------------------PPPPPPPPP 562
Query: 187 PPPSPPQPSRLAPYPHPA 204
PPP PP P P P PA
Sbjct: 563 PPPPPPPPP--PPLPGPA 578
>gi|56549694 enabled homolog isoform a [Homo sapiens]
Length = 591
Score = 58.9 bits (141), Expect = 5e-09
Identities = 48/144 (33%), Positives = 59/144 (40%), Gaps = 39/144 (27%)
Query: 65 DWMTERVDFTALLP--LEPPLPPGTLPQPSPTPPDLEAMASLLKKELEQMEDFFLDAPPL 122
+W ER +A P +E PL L S + P L+A + + +Q + PL
Sbjct: 257 EWERERRISSAAAPASVETPLN-SVLGDSSASEPGLQAASQPAETPSQQG----IVLGPL 311
Query: 123 PPPSPPPLPPPPL--------PPAPSLPLSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEE 174
PP PPPLPP P PP P P LPS P PP
Sbjct: 312 APPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPPP-------------------- 351
Query: 175 VGMPPLP---PPQQPPPPSPPQPS 195
PPLP PP PPPP+PP P+
Sbjct: 352 -PPPPLPNQVPPPPPPPPAPPLPA 374
Score = 45.4 bits (106), Expect = 5e-05
Identities = 31/86 (36%), Positives = 34/86 (39%), Gaps = 18/86 (20%)
Query: 78 PLEPPLPPG------TLPQPS--PTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPPP 129
P PPLPPG LP P P PP L + PPLP PPP
Sbjct: 314 PPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPPPP----------PPPLPNQVPPP 363
Query: 130 LPPPPLPPAPSLPLSLPSFDLPQPPV 155
PPPP PP P+ L S P+
Sbjct: 364 PPPPPAPPLPASGFFLASMSEDNRPL 389
Score = 28.9 bits (63), Expect = 5.3
Identities = 17/51 (33%), Positives = 27/51 (52%)
Query: 209 DRKQKKRDQNKSAALRYRQRKRAEGEALEGECQGLEARNRELKERAESVER 259
+R +++R + + +R+R E E LE E E + RE +ER E ER
Sbjct: 159 ERLERERMERERLERERLERERLERERLEQEQLERERQERERQERLERQER 209
>gi|39930375 enabled homolog isoform b [Homo sapiens]
Length = 570
Score = 58.9 bits (141), Expect = 5e-09
Identities = 48/144 (33%), Positives = 59/144 (40%), Gaps = 39/144 (27%)
Query: 65 DWMTERVDFTALLP--LEPPLPPGTLPQPSPTPPDLEAMASLLKKELEQMEDFFLDAPPL 122
+W ER +A P +E PL L S + P L+A + + +Q + PL
Sbjct: 257 EWERERRISSAAAPASVETPLN-SVLGDSSASEPGLQAASQPAETPSQQG----IVLGPL 311
Query: 123 PPPSPPPLPPPPL--------PPAPSLPLSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEE 174
PP PPPLPP P PP P P LPS P PP
Sbjct: 312 APPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPPP-------------------- 351
Query: 175 VGMPPLP---PPQQPPPPSPPQPS 195
PPLP PP PPPP+PP P+
Sbjct: 352 -PPPPLPNQVPPPPPPPPAPPLPA 374
Score = 45.4 bits (106), Expect = 5e-05
Identities = 31/86 (36%), Positives = 34/86 (39%), Gaps = 18/86 (20%)
Query: 78 PLEPPLPPG------TLPQPS--PTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPPP 129
P PPLPPG LP P P PP L + PPLP PPP
Sbjct: 314 PPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPPPP----------PPPLPNQVPPP 363
Query: 130 LPPPPLPPAPSLPLSLPSFDLPQPPV 155
PPPP PP P+ L S P+
Sbjct: 364 PPPPPAPPLPASGFFLASMSEDNRPL 389
Score = 28.9 bits (63), Expect = 5.3
Identities = 17/51 (33%), Positives = 27/51 (52%)
Query: 209 DRKQKKRDQNKSAALRYRQRKRAEGEALEGECQGLEARNRELKERAESVER 259
+R +++R + + +R+R E E LE E E + RE +ER E ER
Sbjct: 159 ERLERERMERERLERERLERERLERERLEQEQLERERQERERQERLERQER 209
>gi|115387123 protocadherin 15 isoform CD1-4 precursor [Homo sapiens]
Length = 1955
Score = 58.9 bits (141), Expect = 5e-09
Identities = 42/123 (34%), Positives = 50/123 (40%), Gaps = 47/123 (38%)
Query: 78 PLEPPLPPGTLPQPSP--TPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPPPLPPPPL 135
P+ PP PP P P+P PPD+ + PPPSPP + P PL
Sbjct: 1752 PISPPSPP---PAPAPLAPPPDISPFSLF-----------------CPPPSPPSI-PLPL 1790
Query: 136 PPAPSLPLSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPPLPPPQQPPPPS---PP 192
PP PLS+ + P PP+L PP P P PPPPS PP
Sbjct: 1791 PPPTFFPLSVSTSGPPTPPLL---------------------PPFPTPLPPPPPSIPCPP 1829
Query: 193 QPS 195
PS
Sbjct: 1830 PPS 1832
Score = 36.2 bits (82), Expect = 0.033
Identities = 35/112 (31%), Positives = 40/112 (35%), Gaps = 38/112 (33%)
Query: 31 PPAPAPLAPYEVLGGALEGGLPVGGEPLAGDGFSDWMTERVDFTALLPLEPPLPPGTLPQ 90
PPAPAPLAP P P F+ P PP PP ++P
Sbjct: 1759 PPAPAPLAP------------PPDISP---------------FSLFCP--PPSPP-SIPL 1788
Query: 91 PSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPPPLP--PPPLPPAPS 140
P P P S + PP P P PPP P P P PP+ S
Sbjct: 1789 PLPPPTFFPLSVSTSGPPTPPL------LPPFPTPLPPPPPSIPCPPPPSAS 1834
Score = 31.6 bits (70), Expect = 0.82
Identities = 12/24 (50%), Positives = 14/24 (58%)
Query: 120 PPLPPPSPPPLPPPPLPPAPSLPL 143
P +P P+P PPPP PP P L
Sbjct: 1424 PAVPAPAPVAAPPPPPPPPPGAHL 1447
Score = 31.6 bits (70), Expect = 0.82
Identities = 15/24 (62%), Positives = 16/24 (66%), Gaps = 1/24 (4%)
Query: 179 PLPPPQQPPPPSPPQ-PSRLAPYP 201
PLPPP PPSPP P+ LAP P
Sbjct: 1746 PLPPPPPISPPSPPPAPAPLAPPP 1769
Score = 28.5 bits (62), Expect = 6.9
Identities = 12/23 (52%), Positives = 12/23 (52%)
Query: 119 APPLPPPSPPPLPPPPLPPAPSL 141
A P P P P PPPP PP L
Sbjct: 1425 AVPAPAPVAAPPPPPPPPPGAHL 1447
>gi|218505798 protocadherin 15 isoform CD1-10 precursor [Homo sapiens]
Length = 1932
Score = 58.9 bits (141), Expect = 5e-09
Identities = 42/123 (34%), Positives = 50/123 (40%), Gaps = 47/123 (38%)
Query: 78 PLEPPLPPGTLPQPSP--TPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPPPLPPPPL 135
P+ PP PP P P+P PPD+ + PPPSPP + P PL
Sbjct: 1729 PISPPSPP---PAPAPLAPPPDISPFSLF-----------------CPPPSPPSI-PLPL 1767
Query: 136 PPAPSLPLSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPPLPPPQQPPPPS---PP 192
PP PLS+ + P PP+L PP P P PPPPS PP
Sbjct: 1768 PPPTFFPLSVSTSGPPTPPLL---------------------PPFPTPLPPPPPSIPCPP 1806
Query: 193 QPS 195
PS
Sbjct: 1807 PPS 1809
Score = 36.2 bits (82), Expect = 0.033
Identities = 35/112 (31%), Positives = 40/112 (35%), Gaps = 38/112 (33%)
Query: 31 PPAPAPLAPYEVLGGALEGGLPVGGEPLAGDGFSDWMTERVDFTALLPLEPPLPPGTLPQ 90
PPAPAPLAP P P F+ P PP PP ++P
Sbjct: 1736 PPAPAPLAP------------PPDISP---------------FSLFCP--PPSPP-SIPL 1765
Query: 91 PSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPPPLP--PPPLPPAPS 140
P P P S + PP P P PPP P P P PP+ S
Sbjct: 1766 PLPPPTFFPLSVSTSGPPTPPL------LPPFPTPLPPPPPSIPCPPPPSAS 1811
Score = 31.6 bits (70), Expect = 0.82
Identities = 12/24 (50%), Positives = 14/24 (58%)
Query: 120 PPLPPPSPPPLPPPPLPPAPSLPL 143
P +P P+P PPPP PP P L
Sbjct: 1399 PAVPAPAPVAAPPPPPPPPPGAHL 1422
Score = 31.6 bits (70), Expect = 0.82
Identities = 15/24 (62%), Positives = 16/24 (66%), Gaps = 1/24 (4%)
Query: 179 PLPPPQQPPPPSPPQ-PSRLAPYP 201
PLPPP PPSPP P+ LAP P
Sbjct: 1723 PLPPPPPISPPSPPPAPAPLAPPP 1746
Score = 28.5 bits (62), Expect = 6.9
Identities = 12/23 (52%), Positives = 12/23 (52%)
Query: 119 APPLPPPSPPPLPPPPLPPAPSL 141
A P P P P PPPP PP L
Sbjct: 1400 AVPAPAPVAAPPPPPPPPPGAHL 1422
>gi|218505785 protocadherin 15 isoform CD1-9 precursor [Homo sapiens]
Length = 1935
Score = 58.9 bits (141), Expect = 5e-09
Identities = 42/123 (34%), Positives = 50/123 (40%), Gaps = 47/123 (38%)
Query: 78 PLEPPLPPGTLPQPSP--TPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPPPLPPPPL 135
P+ PP PP P P+P PPD+ + PPPSPP + P PL
Sbjct: 1732 PISPPSPP---PAPAPLAPPPDISPFSLF-----------------CPPPSPPSI-PLPL 1770
Query: 136 PPAPSLPLSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPPLPPPQQPPPPS---PP 192
PP PLS+ + P PP+L PP P P PPPPS PP
Sbjct: 1771 PPPTFFPLSVSTSGPPTPPLL---------------------PPFPTPLPPPPPSIPCPP 1809
Query: 193 QPS 195
PS
Sbjct: 1810 PPS 1812
Score = 36.2 bits (82), Expect = 0.033
Identities = 35/112 (31%), Positives = 40/112 (35%), Gaps = 38/112 (33%)
Query: 31 PPAPAPLAPYEVLGGALEGGLPVGGEPLAGDGFSDWMTERVDFTALLPLEPPLPPGTLPQ 90
PPAPAPLAP P P F+ P PP PP ++P
Sbjct: 1739 PPAPAPLAP------------PPDISP---------------FSLFCP--PPSPP-SIPL 1768
Query: 91 PSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPPPLP--PPPLPPAPS 140
P P P S + PP P P PPP P P P PP+ S
Sbjct: 1769 PLPPPTFFPLSVSTSGPPTPPL------LPPFPTPLPPPPPSIPCPPPPSAS 1814
Score = 31.6 bits (70), Expect = 0.82
Identities = 12/24 (50%), Positives = 14/24 (58%)
Query: 120 PPLPPPSPPPLPPPPLPPAPSLPL 143
P +P P+P PPPP PP P L
Sbjct: 1402 PAVPAPAPVAAPPPPPPPPPGAHL 1425
Score = 31.6 bits (70), Expect = 0.82
Identities = 15/24 (62%), Positives = 16/24 (66%), Gaps = 1/24 (4%)
Query: 179 PLPPPQQPPPPSPPQ-PSRLAPYP 201
PLPPP PPSPP P+ LAP P
Sbjct: 1726 PLPPPPPISPPSPPPAPAPLAPPP 1749
Score = 28.5 bits (62), Expect = 6.9
Identities = 12/23 (52%), Positives = 12/23 (52%)
Query: 119 APPLPPPSPPPLPPPPLPPAPSL 141
A P P P P PPPP PP L
Sbjct: 1403 AVPAPAPVAAPPPPPPPPPGAHL 1425
>gi|218505783 protocadherin 15 isoform CD1-8 precursor [Homo sapiens]
Length = 1915
Score = 58.9 bits (141), Expect = 5e-09
Identities = 42/123 (34%), Positives = 50/123 (40%), Gaps = 47/123 (38%)
Query: 78 PLEPPLPPGTLPQPSP--TPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPPPLPPPPL 135
P+ PP PP P P+P PPD+ + PPPSPP + P PL
Sbjct: 1712 PISPPSPP---PAPAPLAPPPDISPFSLF-----------------CPPPSPPSI-PLPL 1750
Query: 136 PPAPSLPLSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPPLPPPQQPPPPS---PP 192
PP PLS+ + P PP+L PP P P PPPPS PP
Sbjct: 1751 PPPTFFPLSVSTSGPPTPPLL---------------------PPFPTPLPPPPPSIPCPP 1789
Query: 193 QPS 195
PS
Sbjct: 1790 PPS 1792
Score = 36.2 bits (82), Expect = 0.033
Identities = 35/112 (31%), Positives = 40/112 (35%), Gaps = 38/112 (33%)
Query: 31 PPAPAPLAPYEVLGGALEGGLPVGGEPLAGDGFSDWMTERVDFTALLPLEPPLPPGTLPQ 90
PPAPAPLAP P P F+ P PP PP ++P
Sbjct: 1719 PPAPAPLAP------------PPDISP---------------FSLFCP--PPSPP-SIPL 1748
Query: 91 PSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPPPLP--PPPLPPAPS 140
P P P S + PP P P PPP P P P PP+ S
Sbjct: 1749 PLPPPTFFPLSVSTSGPPTPPL------LPPFPTPLPPPPPSIPCPPPPSAS 1794
Score = 31.6 bits (70), Expect = 0.82
Identities = 12/24 (50%), Positives = 14/24 (58%)
Query: 120 PPLPPPSPPPLPPPPLPPAPSLPL 143
P +P P+P PPPP PP P L
Sbjct: 1384 PAVPAPAPVAAPPPPPPPPPGAHL 1407
Score = 31.6 bits (70), Expect = 0.82
Identities = 15/24 (62%), Positives = 16/24 (66%), Gaps = 1/24 (4%)
Query: 179 PLPPPQQPPPPSPPQ-PSRLAPYP 201
PLPPP PPSPP P+ LAP P
Sbjct: 1706 PLPPPPPISPPSPPPAPAPLAPPP 1729
Score = 28.5 bits (62), Expect = 6.9
Identities = 12/23 (52%), Positives = 12/23 (52%)
Query: 119 APPLPPPSPPPLPPPPLPPAPSL 141
A P P P P PPPP PP L
Sbjct: 1385 AVPAPAPVAAPPPPPPPPPGAHL 1407
>gi|218505781 protocadherin 15 isoform CD1-7 precursor [Homo sapiens]
Length = 1952
Score = 58.9 bits (141), Expect = 5e-09
Identities = 42/123 (34%), Positives = 50/123 (40%), Gaps = 47/123 (38%)
Query: 78 PLEPPLPPGTLPQPSP--TPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPPPLPPPPL 135
P+ PP PP P P+P PPD+ + PPPSPP + P PL
Sbjct: 1749 PISPPSPP---PAPAPLAPPPDISPFSLF-----------------CPPPSPPSI-PLPL 1787
Query: 136 PPAPSLPLSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPPLPPPQQPPPPS---PP 192
PP PLS+ + P PP+L PP P P PPPPS PP
Sbjct: 1788 PPPTFFPLSVSTSGPPTPPLL---------------------PPFPTPLPPPPPSIPCPP 1826
Query: 193 QPS 195
PS
Sbjct: 1827 PPS 1829
Score = 36.2 bits (82), Expect = 0.033
Identities = 35/112 (31%), Positives = 40/112 (35%), Gaps = 38/112 (33%)
Query: 31 PPAPAPLAPYEVLGGALEGGLPVGGEPLAGDGFSDWMTERVDFTALLPLEPPLPPGTLPQ 90
PPAPAPLAP P P F+ P PP PP ++P
Sbjct: 1756 PPAPAPLAP------------PPDISP---------------FSLFCP--PPSPP-SIPL 1785
Query: 91 PSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPPPLP--PPPLPPAPS 140
P P P S + PP P P PPP P P P PP+ S
Sbjct: 1786 PLPPPTFFPLSVSTSGPPTPPL------LPPFPTPLPPPPPSIPCPPPPSAS 1831
Score = 31.6 bits (70), Expect = 0.82
Identities = 12/24 (50%), Positives = 14/24 (58%)
Query: 120 PPLPPPSPPPLPPPPLPPAPSLPL 143
P +P P+P PPPP PP P L
Sbjct: 1421 PAVPAPAPVAAPPPPPPPPPGAHL 1444
Score = 31.6 bits (70), Expect = 0.82
Identities = 15/24 (62%), Positives = 16/24 (66%), Gaps = 1/24 (4%)
Query: 179 PLPPPQQPPPPSPPQ-PSRLAPYP 201
PLPPP PPSPP P+ LAP P
Sbjct: 1743 PLPPPPPISPPSPPPAPAPLAPPP 1766
Score = 28.5 bits (62), Expect = 6.9
Identities = 12/23 (52%), Positives = 12/23 (52%)
Query: 119 APPLPPPSPPPLPPPPLPPAPSL 141
A P P P P PPPP PP L
Sbjct: 1422 AVPAPAPVAAPPPPPPPPPGAHL 1444
>gi|218505779 protocadherin 15 isoform CD1-6 precursor [Homo sapiens]
Length = 1886
Score = 58.9 bits (141), Expect = 5e-09
Identities = 42/123 (34%), Positives = 50/123 (40%), Gaps = 47/123 (38%)
Query: 78 PLEPPLPPGTLPQPSP--TPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPPPLPPPPL 135
P+ PP PP P P+P PPD+ + PPPSPP + P PL
Sbjct: 1683 PISPPSPP---PAPAPLAPPPDISPFSLF-----------------CPPPSPPSI-PLPL 1721
Query: 136 PPAPSLPLSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPPLPPPQQPPPPS---PP 192
PP PLS+ + P PP+L PP P P PPPPS PP
Sbjct: 1722 PPPTFFPLSVSTSGPPTPPLL---------------------PPFPTPLPPPPPSIPCPP 1760
Query: 193 QPS 195
PS
Sbjct: 1761 PPS 1763
Score = 36.2 bits (82), Expect = 0.033
Identities = 35/112 (31%), Positives = 40/112 (35%), Gaps = 38/112 (33%)
Query: 31 PPAPAPLAPYEVLGGALEGGLPVGGEPLAGDGFSDWMTERVDFTALLPLEPPLPPGTLPQ 90
PPAPAPLAP P P F+ P PP PP ++P
Sbjct: 1690 PPAPAPLAP------------PPDISP---------------FSLFCP--PPSPP-SIPL 1719
Query: 91 PSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPPPLP--PPPLPPAPS 140
P P P S + PP P P PPP P P P PP+ S
Sbjct: 1720 PLPPPTFFPLSVSTSGPPTPPL------LPPFPTPLPPPPPSIPCPPPPSAS 1765
Score = 31.6 bits (70), Expect = 0.82
Identities = 12/24 (50%), Positives = 14/24 (58%)
Query: 120 PPLPPPSPPPLPPPPLPPAPSLPL 143
P +P P+P PPPP PP P L
Sbjct: 1353 PAVPAPAPVAAPPPPPPPPPGAHL 1376
Score = 31.6 bits (70), Expect = 0.82
Identities = 15/24 (62%), Positives = 16/24 (66%), Gaps = 1/24 (4%)
Query: 179 PLPPPQQPPPPSPPQ-PSRLAPYP 201
PLPPP PPSPP P+ LAP P
Sbjct: 1677 PLPPPPPISPPSPPPAPAPLAPPP 1700
Score = 28.5 bits (62), Expect = 6.9
Identities = 12/23 (52%), Positives = 12/23 (52%)
Query: 119 APPLPPPSPPPLPPPPLPPAPSL 141
A P P P P PPPP PP L
Sbjct: 1354 AVPAPAPVAAPPPPPPPPPGAHL 1376
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.138 0.424
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,375,146
Number of Sequences: 37866
Number of extensions: 1418630
Number of successful extensions: 53779
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1096
Number of HSP's successfully gapped in prelim test: 1271
Number of HSP's that attempted gapping in prelim test: 13789
Number of HSP's gapped (non-prelim): 16422
length of query: 282
length of database: 18,247,518
effective HSP length: 101
effective length of query: 181
effective length of database: 14,423,052
effective search space: 2610572412
effective search space used: 2610572412
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.