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Search of human proteins with 42544123
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|42544123 splicing factor 1 isoform 3 [Homo sapiens]
(548 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|42544123 splicing factor 1 isoform 3 [Homo sapiens] 1163 0.0
gi|42544125 splicing factor 1 isoform 2 [Homo sapiens] 1122 0.0
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] 1122 0.0
gi|42544127 splicing factor 1 isoform 4 [Homo sapiens] 112 7e-25
gi|45827712 quaking homolog, KH domain RNA binding isoform HQK-7... 100 4e-21
gi|45827710 quaking homolog, KH domain RNA binding isoform HQK-7... 100 4e-21
gi|45827708 quaking homolog, KH domain RNA binding isoform HQK-6... 100 4e-21
gi|45827706 quaking homolog, KH domain RNA binding isoform HQK-5... 100 4e-21
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] 99 1e-20
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 91 3e-18
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H... 90 5e-18
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 90 6e-18
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 89 8e-18
gi|18959210 WIRE protein [Homo sapiens] 89 1e-17
gi|11386183 WAS protein family, member 2 [Homo sapiens] 89 1e-17
gi|160707881 formin 2 [Homo sapiens] 87 5e-17
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 86 9e-17
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 86 9e-17
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 86 9e-17
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 84 3e-16
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 84 3e-16
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 84 3e-16
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 84 3e-16
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 83 6e-16
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 82 1e-15
gi|5730073 KH domain containing, RNA binding, signal transductio... 82 2e-15
gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens] 81 2e-15
gi|189217895 KH domain-containing, RNA-binding, signal transduct... 81 3e-15
gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens] 80 4e-15
gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Ho... 80 6e-15
>gi|42544123 splicing factor 1 isoform 3 [Homo sapiens]
Length = 548
Score = 1163 bits (3009), Expect = 0.0
Identities = 548/548 (100%), Positives = 548/548 (100%)
Query: 1 MATGANATPLDFPSKKRKRSRWNQDTMEQKTVIPGMPTVIPPGLTREQERAYIVQLQIED 60
MATGANATPLDFPSKKRKRSRWNQDTMEQKTVIPGMPTVIPPGLTREQERAYIVQLQIED
Sbjct: 1 MATGANATPLDFPSKKRKRSRWNQDTMEQKTVIPGMPTVIPPGLTREQERAYIVQLQIED 60
Query: 61 LTRKLRTGDLGIPPNPEDRSPSPEPIYNSEGKRLNTREFRTRKKLEEERHNLITEMVALN 120
LTRKLRTGDLGIPPNPEDRSPSPEPIYNSEGKRLNTREFRTRKKLEEERHNLITEMVALN
Sbjct: 61 LTRKLRTGDLGIPPNPEDRSPSPEPIYNSEGKRLNTREFRTRKKLEEERHNLITEMVALN 120
Query: 121 PDFKPPADYKPPATRVSDKVMIPQDEYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGK 180
PDFKPPADYKPPATRVSDKVMIPQDEYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGK
Sbjct: 121 PDFKPPADYKPPATRVSDKVMIPQDEYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGK 180
Query: 181 GSVKEGKVGRKDGQMLPGEDEPLHALVTANTMENVKKAVEQIRNILKQGIETPEDQNDLR 240
GSVKEGKVGRKDGQMLPGEDEPLHALVTANTMENVKKAVEQIRNILKQGIETPEDQNDLR
Sbjct: 181 GSVKEGKVGRKDGQMLPGEDEPLHALVTANTMENVKKAVEQIRNILKQGIETPEDQNDLR 240
Query: 241 KMQLRELARLNGTLREDDNRILRPWQSSETRSITNTTVCTKCGGAGHIASDCKFQRPGDP 300
KMQLRELARLNGTLREDDNRILRPWQSSETRSITNTTVCTKCGGAGHIASDCKFQRPGDP
Sbjct: 241 KMQLRELARLNGTLREDDNRILRPWQSSETRSITNTTVCTKCGGAGHIASDCKFQRPGDP 300
Query: 301 QSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMS 360
QSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMS
Sbjct: 301 QSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMS 360
Query: 361 TTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGP 420
TTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGP
Sbjct: 361 TTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGP 420
Query: 421 PPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPP 480
PPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPP
Sbjct: 421 PPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPP 480
Query: 481 PPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQRSLPAAAMARAMR 540
PPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQRSLPAAAMARAMR
Sbjct: 481 PPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQRSLPAAAMARAMR 540
Query: 541 VRTFRAHW 548
VRTFRAHW
Sbjct: 541 VRTFRAHW 548
>gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]
Length = 638
Score = 1122 bits (2903), Expect = 0.0
Identities = 528/536 (98%), Positives = 529/536 (98%)
Query: 1 MATGANATPLDFPSKKRKRSRWNQDTMEQKTVIPGMPTVIPPGLTREQERAYIVQLQIED 60
MATGANATPLDFPSKKRKRSRWNQDTMEQKTVIPGMPTVIPPGLTREQERAYIVQLQIED
Sbjct: 1 MATGANATPLDFPSKKRKRSRWNQDTMEQKTVIPGMPTVIPPGLTREQERAYIVQLQIED 60
Query: 61 LTRKLRTGDLGIPPNPEDRSPSPEPIYNSEGKRLNTREFRTRKKLEEERHNLITEMVALN 120
LTRKLRTGDLGIPPNPEDRSPSPEPIYNSEGKRLNTREFRTRKKLEEERHNLITEMVALN
Sbjct: 61 LTRKLRTGDLGIPPNPEDRSPSPEPIYNSEGKRLNTREFRTRKKLEEERHNLITEMVALN 120
Query: 121 PDFKPPADYKPPATRVSDKVMIPQDEYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGK 180
PDFKPPADYKPPATRVSDKVMIPQDEYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGK
Sbjct: 121 PDFKPPADYKPPATRVSDKVMIPQDEYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGK 180
Query: 181 GSVKEGKVGRKDGQMLPGEDEPLHALVTANTMENVKKAVEQIRNILKQGIETPEDQNDLR 240
GSVKEGKVGRKDGQMLPGEDEPLHALVTANTMENVKKAVEQIRNILKQGIETPEDQNDLR
Sbjct: 181 GSVKEGKVGRKDGQMLPGEDEPLHALVTANTMENVKKAVEQIRNILKQGIETPEDQNDLR 240
Query: 241 KMQLRELARLNGTLREDDNRILRPWQSSETRSITNTTVCTKCGGAGHIASDCKFQRPGDP 300
KMQLRELARLNGTLREDDNRILRPWQSSETRSITNTTVCTKCGGAGHIASDCKFQRPGDP
Sbjct: 241 KMQLRELARLNGTLREDDNRILRPWQSSETRSITNTTVCTKCGGAGHIASDCKFQRPGDP 300
Query: 301 QSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMS 360
QSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMS
Sbjct: 301 QSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMS 360
Query: 361 TTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGP 420
TTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGP
Sbjct: 361 TTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGP 420
Query: 421 PPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPP 480
PPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPP
Sbjct: 421 PPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPP 480
Query: 481 PPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQRSLPAAAMA 536
PPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQ + A
Sbjct: 481 PPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSA 536
Score = 32.0 bits (71), Expect = 1.5
Identities = 37/143 (25%), Positives = 40/143 (27%), Gaps = 45/143 (31%)
Query: 264 PWQSSETRSITNTTVCTKCGGAGHIASDCKFQRPGDPQSAQDKARMDKEYLSLMAELGEA 323
PWQ NTT T G G I P Q A A
Sbjct: 524 PWQQ-------NTTTTTTSAGTGSIP-------PWQQQQA-----------------AAA 552
Query: 324 PVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMH 383
P + P PL +P P PPPP PP S P
Sbjct: 553 ASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPP--------PPPPGSAGMMIPP----- 599
Query: 384 GGGPGGPGGGPHSFPHPLPSLTG 406
G GP FP PL +L G
Sbjct: 600 -RGGDGPSHESEDFPRPLVTLPG 621
>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
Length = 639
Score = 1122 bits (2903), Expect = 0.0
Identities = 528/536 (98%), Positives = 529/536 (98%)
Query: 1 MATGANATPLDFPSKKRKRSRWNQDTMEQKTVIPGMPTVIPPGLTREQERAYIVQLQIED 60
MATGANATPLDFPSKKRKRSRWNQDTMEQKTVIPGMPTVIPPGLTREQERAYIVQLQIED
Sbjct: 1 MATGANATPLDFPSKKRKRSRWNQDTMEQKTVIPGMPTVIPPGLTREQERAYIVQLQIED 60
Query: 61 LTRKLRTGDLGIPPNPEDRSPSPEPIYNSEGKRLNTREFRTRKKLEEERHNLITEMVALN 120
LTRKLRTGDLGIPPNPEDRSPSPEPIYNSEGKRLNTREFRTRKKLEEERHNLITEMVALN
Sbjct: 61 LTRKLRTGDLGIPPNPEDRSPSPEPIYNSEGKRLNTREFRTRKKLEEERHNLITEMVALN 120
Query: 121 PDFKPPADYKPPATRVSDKVMIPQDEYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGK 180
PDFKPPADYKPPATRVSDKVMIPQDEYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGK
Sbjct: 121 PDFKPPADYKPPATRVSDKVMIPQDEYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGK 180
Query: 181 GSVKEGKVGRKDGQMLPGEDEPLHALVTANTMENVKKAVEQIRNILKQGIETPEDQNDLR 240
GSVKEGKVGRKDGQMLPGEDEPLHALVTANTMENVKKAVEQIRNILKQGIETPEDQNDLR
Sbjct: 181 GSVKEGKVGRKDGQMLPGEDEPLHALVTANTMENVKKAVEQIRNILKQGIETPEDQNDLR 240
Query: 241 KMQLRELARLNGTLREDDNRILRPWQSSETRSITNTTVCTKCGGAGHIASDCKFQRPGDP 300
KMQLRELARLNGTLREDDNRILRPWQSSETRSITNTTVCTKCGGAGHIASDCKFQRPGDP
Sbjct: 241 KMQLRELARLNGTLREDDNRILRPWQSSETRSITNTTVCTKCGGAGHIASDCKFQRPGDP 300
Query: 301 QSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMS 360
QSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMS
Sbjct: 301 QSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMS 360
Query: 361 TTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGP 420
TTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGP
Sbjct: 361 TTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGP 420
Query: 421 PPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPP 480
PPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPP
Sbjct: 421 PPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPP 480
Query: 481 PPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQRSLPAAAMA 536
PPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQ + A
Sbjct: 481 PPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSA 536
Score = 68.2 bits (165), Expect = 2e-11
Identities = 57/180 (31%), Positives = 66/180 (36%), Gaps = 42/180 (23%)
Query: 324 PVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWM--------NSGPSE 375
P P G P + PL + PPPPS + + PW ++G
Sbjct: 481 PPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGS 540
Query: 376 SRPYHGMHGGGPGGPG-----GGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPP 430
P+ PG G P P P G P PPPP PPPP
Sbjct: 541 IPPWQQQQAAAAASPGAPQMQGNPTMVPLP--------PGVQPPLPPGAPPPP---PPPP 589
Query: 431 PMNQG-----PHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPP 485
P + G P PP PPPMD T +G GV GM PP GM P PPPPP
Sbjct: 590 PGSAGMMYAPPPPP----PPPMDPSNFVTMMGMGV------AGM---PPFGMPPAPPPPP 636
Score = 34.7 bits (78), Expect = 0.23
Identities = 45/170 (26%), Positives = 53/170 (31%), Gaps = 54/170 (31%)
Query: 264 PWQSSETRSITNTTVCTKCGGAGHIASDCKFQRPGDPQSAQDKARMDKEYLSLMAELGEA 323
PWQ NTT T G G I P Q A A
Sbjct: 524 PWQQ-------NTTTTTTSAGTGSIP-------PWQQQQA-----------------AAA 552
Query: 324 PVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMH 383
P + P PL +P P PPPP PP ++G + P
Sbjct: 553 ASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPP-------PPPPPGSAGMMYAPP----- 600
Query: 384 GGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMN 433
P P P +F + + G G P P G PP PPPPP N
Sbjct: 601 --PPPPPPMDPSNF---VTMMGMGVAGMP----PFGMPP--APPPPPPQN 639
>gi|42544127 splicing factor 1 isoform 4 [Homo sapiens]
Length = 80
Score = 112 bits (281), Expect = 7e-25
Identities = 56/68 (82%), Positives = 59/68 (86%), Gaps = 6/68 (8%)
Query: 1 MATGANATPLDFPSKKRKRSRWNQDTMEQKTVIPGMPTVIPPGLTREQERAYI------V 54
MATGANATPLDFPSKKRKRSRWNQDTMEQKTVIPGMPTVIPPGLTREQERAYI +
Sbjct: 1 MATGANATPLDFPSKKRKRSRWNQDTMEQKTVIPGMPTVIPPGLTREQERAYIGKYTFCI 60
Query: 55 QLQIEDLT 62
Q+ E +T
Sbjct: 61 QMHFEIVT 68
>gi|45827712 quaking homolog, KH domain RNA binding isoform HQK-7B
[Homo sapiens]
Length = 319
Score = 100 bits (248), Expect = 4e-21
Identities = 64/181 (35%), Positives = 100/181 (55%), Gaps = 21/181 (11%)
Query: 86 IYNSEGKRLNTREFRTRKKLEEERHNLITEMVALNPDFKPPADYKPPATRVSDKVMIPQD 145
I+N + L+ R RK + + N TE + D P ++ +K+ +P
Sbjct: 37 IFNHLERLLDEEISRVRKDMYNDTLNGSTEKRSAELP-----DAVGPIVQLQEKLYVPVK 91
Query: 146 EYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGKGSVKEGKV-----GRKDGQMLPGED 200
EYP+ NFVG ++GPRG T K +E E KIM+RGKGS+++ K G+ + + L +
Sbjct: 92 EYPDFNFVGRILGPRGLTAKQLEAETGCKIMVRGKGSMRDKKKEEQNRGKPNWEHL---N 148
Query: 201 EPLHALVTANTMEN-----VKKAVEQIRNILKQGIETPEDQNDLRKMQLRELARLNGTLR 255
E LH L+T +N +K+AVE+++ +L + E ++ L+KMQL ELA LNGT R
Sbjct: 149 EDLHVLITVEDAQNRAEIKLKRAVEEVKKLL---VPAAEGEDSLKKMQLMELAILNGTYR 205
Query: 256 E 256
+
Sbjct: 206 D 206
>gi|45827710 quaking homolog, KH domain RNA binding isoform HQK-7
[Homo sapiens]
Length = 325
Score = 100 bits (248), Expect = 4e-21
Identities = 64/181 (35%), Positives = 100/181 (55%), Gaps = 21/181 (11%)
Query: 86 IYNSEGKRLNTREFRTRKKLEEERHNLITEMVALNPDFKPPADYKPPATRVSDKVMIPQD 145
I+N + L+ R RK + + N TE + D P ++ +K+ +P
Sbjct: 37 IFNHLERLLDEEISRVRKDMYNDTLNGSTEKRSAELP-----DAVGPIVQLQEKLYVPVK 91
Query: 146 EYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGKGSVKEGKV-----GRKDGQMLPGED 200
EYP+ NFVG ++GPRG T K +E E KIM+RGKGS+++ K G+ + + L +
Sbjct: 92 EYPDFNFVGRILGPRGLTAKQLEAETGCKIMVRGKGSMRDKKKEEQNRGKPNWEHL---N 148
Query: 201 EPLHALVTANTMEN-----VKKAVEQIRNILKQGIETPEDQNDLRKMQLRELARLNGTLR 255
E LH L+T +N +K+AVE+++ +L + E ++ L+KMQL ELA LNGT R
Sbjct: 149 EDLHVLITVEDAQNRAEIKLKRAVEEVKKLL---VPAAEGEDSLKKMQLMELAILNGTYR 205
Query: 256 E 256
+
Sbjct: 206 D 206
>gi|45827708 quaking homolog, KH domain RNA binding isoform HQK-6
[Homo sapiens]
Length = 319
Score = 100 bits (248), Expect = 4e-21
Identities = 64/181 (35%), Positives = 100/181 (55%), Gaps = 21/181 (11%)
Query: 86 IYNSEGKRLNTREFRTRKKLEEERHNLITEMVALNPDFKPPADYKPPATRVSDKVMIPQD 145
I+N + L+ R RK + + N TE + D P ++ +K+ +P
Sbjct: 37 IFNHLERLLDEEISRVRKDMYNDTLNGSTEKRSAELP-----DAVGPIVQLQEKLYVPVK 91
Query: 146 EYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGKGSVKEGKV-----GRKDGQMLPGED 200
EYP+ NFVG ++GPRG T K +E E KIM+RGKGS+++ K G+ + + L +
Sbjct: 92 EYPDFNFVGRILGPRGLTAKQLEAETGCKIMVRGKGSMRDKKKEEQNRGKPNWEHL---N 148
Query: 201 EPLHALVTANTMEN-----VKKAVEQIRNILKQGIETPEDQNDLRKMQLRELARLNGTLR 255
E LH L+T +N +K+AVE+++ +L + E ++ L+KMQL ELA LNGT R
Sbjct: 149 EDLHVLITVEDAQNRAEIKLKRAVEEVKKLL---VPAAEGEDSLKKMQLMELAILNGTYR 205
Query: 256 E 256
+
Sbjct: 206 D 206
>gi|45827706 quaking homolog, KH domain RNA binding isoform HQK-5
[Homo sapiens]
Length = 341
Score = 100 bits (248), Expect = 4e-21
Identities = 64/181 (35%), Positives = 100/181 (55%), Gaps = 21/181 (11%)
Query: 86 IYNSEGKRLNTREFRTRKKLEEERHNLITEMVALNPDFKPPADYKPPATRVSDKVMIPQD 145
I+N + L+ R RK + + N TE + D P ++ +K+ +P
Sbjct: 37 IFNHLERLLDEEISRVRKDMYNDTLNGSTEKRSAELP-----DAVGPIVQLQEKLYVPVK 91
Query: 146 EYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGKGSVKEGKV-----GRKDGQMLPGED 200
EYP+ NFVG ++GPRG T K +E E KIM+RGKGS+++ K G+ + + L +
Sbjct: 92 EYPDFNFVGRILGPRGLTAKQLEAETGCKIMVRGKGSMRDKKKEEQNRGKPNWEHL---N 148
Query: 201 EPLHALVTANTMEN-----VKKAVEQIRNILKQGIETPEDQNDLRKMQLRELARLNGTLR 255
E LH L+T +N +K+AVE+++ +L + E ++ L+KMQL ELA LNGT R
Sbjct: 149 EDLHVLITVEDAQNRAEIKLKRAVEEVKKLL---VPAAEGEDSLKKMQLMELAILNGTYR 205
Query: 256 E 256
+
Sbjct: 206 D 206
>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
Length = 424
Score = 99.0 bits (245), Expect = 1e-20
Identities = 77/216 (35%), Positives = 86/216 (39%), Gaps = 25/216 (11%)
Query: 316 LMAELGEA-PVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPS 374
+++ LG P P S P P A P P PPPP PP + P
Sbjct: 224 VVSSLGSGLPPPGMPPPGSFPPPVPPPGALPPGIPPAMPPPPMPPGAAGHGPPSAGT-PG 282
Query: 375 ESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQ 434
P HG P PGG PH P HG H + H GPP QPPP P
Sbjct: 283 AGHPGHGHSHPHPFPPGGMPH--PGMSQMQLAHHGPHGLGHPHAGPPGSGGQPPPRPPPG 340
Query: 435 GPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPP----SGQPP 490
PHP GPPPM P GS + H G P PP GM PPP P +G P
Sbjct: 341 MPHP----GPPPMGMPPRGPPFGSPMG--HPG----PMPPHGMRGPPPLMPPHGYTGPPR 390
Query: 491 PPP----SGPLPPWQQQQQQPPPPPPPSSSMASSTP 522
PPP GPLPP + P PP PP + P
Sbjct: 391 PPPYGYQRGPLPP---PRPTPRPPVPPRGPLRGPLP 423
Score = 47.8 bits (112), Expect = 3e-05
Identities = 27/63 (42%), Positives = 28/63 (44%), Gaps = 12/63 (19%)
Query: 462 RLHQGKGMMPPPPM-----------GMMPPPPPPPSGQPPP-PPSGPLPPWQQQQQQPPP 509
R HQ PPPP G+ PP PPP PPP PP G LPP PPP
Sbjct: 206 RPHQLFADAPPPPSAPNPVVSSLGSGLPPPGMPPPGSFPPPVPPPGALPPGIPPAMPPPP 265
Query: 510 PPP 512
PP
Sbjct: 266 MPP 268
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 90.9 bits (224), Expect = 3e-18
Identities = 70/184 (38%), Positives = 78/184 (42%), Gaps = 35/184 (19%)
Query: 364 SRPPWMNSGPSESRPYHGMHGG----GPGGPGGGPHSFPH----PLPSLTGGHGGHPMQH 415
SR + G R + GG GP GPGG P FP P P L G P
Sbjct: 193 SRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPL-----GPPGPP 247
Query: 416 NPNGPPPPWMQPPPP---PMNQGPHPPGHHGPPPM--DQYLGSTPVGSGVYRLHQGKGMM 470
P GPPPP PPP P N+G PP PP + Q G P+G L G
Sbjct: 248 GPPGPPPPGQVLPPPLAGPPNRGDRPP----PPVLFPGQPFGQPPLGP----LPPGP--- 296
Query: 471 PPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQRSL 530
PPP G PPP PPP Q PPPP GP PP +PP P P ++A LP
Sbjct: 297 PPPVPGYGPPPGPPPPQQGPPPPPGPFPP------RPPGPLGPPLTLAPPPHLPGPPPGA 350
Query: 531 PAAA 534
P A
Sbjct: 351 PPPA 354
Score = 80.5 bits (197), Expect = 4e-15
Identities = 81/279 (29%), Positives = 102/279 (36%), Gaps = 34/279 (12%)
Query: 276 TTVCTKCGGAGHIASDCKFQRPGDPQSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGP 335
TT + G G R PQ + + R A G P G P
Sbjct: 174 TTQSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPG------AVPGGDRFPGPAGPGGPP 227
Query: 336 ATTPLASAPR--PAAPANNPPPPSLMSTTQSRPPWMNSGPSE-SRPYHGMHGGGPGGPGG 392
P P P P P PP Q PP + P+ RP + PG P G
Sbjct: 228 PPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVL--FPGQPFG 285
Query: 393 GPHSFPHP--LPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPP---PM 447
P P P P G+G P GPPPP PPPPP P PPG GPP
Sbjct: 286 QPPLGPLPPGPPPPVPGYG------PPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAP 339
Query: 448 DQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMP------PPPPPPSGQPPPPPSGPL-PPW 500
+L P G+ H PPP MP PPP P G+PPP G PP
Sbjct: 340 PPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPG 399
Query: 501 QQQQQQPPPPPPPSSSMASSTPLPWQQRSLPAAAMARAM 539
++ P S A + + R++ ++A++RA+
Sbjct: 400 REMDTARTP-----LSEAEFEEIMNRNRAISSSAISRAV 433
>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
sapiens]
Length = 309
Score = 90.1 bits (222), Expect = 5e-18
Identities = 74/232 (31%), Positives = 83/232 (35%), Gaps = 48/232 (20%)
Query: 296 RPGDPQSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANNPP- 354
RPG P+ + + E P P + GP PRP P PP
Sbjct: 95 RPGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPP-------PRPGKPEGPPPQ 147
Query: 355 -------PPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGG 407
PP + PP S+ P H GP GG P P P G
Sbjct: 148 GGNQSQGPPPRPGKPEGPPP-QGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEG 206
Query: 408 ---HGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLH 464
GG+ Q GPPP +P PP G P GPPP H
Sbjct: 207 PPPQGGNQSQ----GPPPRPGKPEGPPSQGGNKP---QGPPP-----------------H 242
Query: 465 QGKGMMPPPPMGMMPPPPPPPSG-QPPPPPSG----PLPPWQQQQQQPPPPP 511
GK PPP G P PPPP Q PPPP G PLPP + Q PPPPP
Sbjct: 243 PGKPQGPPPQEGNKPQRPPPPGRPQGPPPPGGNPQQPLPPPAGKPQGPPPPP 294
Score = 78.2 bits (191), Expect = 2e-14
Identities = 74/226 (32%), Positives = 83/226 (36%), Gaps = 49/226 (21%)
Query: 344 PRPAAPANNPP--------PPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPH 395
PRP P PP PP + +PP S+ P GP GG
Sbjct: 73 PRPGKPEGPPPQGGNQSQGPPPRPGKPEGQPP-QGGNQSQGPPPRPGKPEGPPPQGGNQS 131
Query: 396 SFPHPLPSLTGG---HGGHPMQHNPNGPPP-PWMQPPPPP----MNQG--PHPPGHHGPP 445
P P P G GG+ Q GPPP P PPP +QG PHP GPP
Sbjct: 132 QGPPPRPGKPEGPPPQGGNQSQ----GPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPP 187
Query: 446 PM--DQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPS-------GP 496
P +Q G P GK PPP G PPP G+P PPS GP
Sbjct: 188 PQGGNQSQGPPP--------RPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGP 239
Query: 497 LPPWQQQQQQPPP--------PPPPSSSMASSTPLPWQQRSLPAAA 534
PP + Q PPP PPPP P Q+ LP A
Sbjct: 240 -PPHPGKPQGPPPQEGNKPQRPPPPGRPQGPPPPGGNPQQPLPPPA 284
Score = 71.2 bits (173), Expect = 2e-12
Identities = 66/200 (33%), Positives = 71/200 (35%), Gaps = 50/200 (25%)
Query: 349 PANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGH 408
P PPPP + RPP S+ P GP GG P P P G
Sbjct: 47 PQRTPPPPG---KPEGRPP-QGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQ 102
Query: 409 ---------GGHPMQHNPNGPPP------------PWMQPPPPP----MNQGPHP-PGH- 441
G P P GPPP P PPP +QGP P PG
Sbjct: 103 PPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKP 162
Query: 442 HGPPPM--DQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPP 499
GPPP +Q G P H GK PPP G PPP G+P PP P
Sbjct: 163 EGPPPQGGNQSQGPPP--------HPGKPEGPPPQGGNQSQGPPPRPGKPEGPP----PQ 210
Query: 500 WQQQQQQPPPPP-----PPS 514
Q Q PPP P PPS
Sbjct: 211 GGNQSQGPPPRPGKPEGPPS 230
Score = 59.3 bits (142), Expect = 9e-09
Identities = 46/131 (35%), Positives = 49/131 (37%), Gaps = 23/131 (17%)
Query: 410 GHPMQHNPNGPPPPWMQPPPPPMNQGPHPPG---HHGPPPMDQYLGSTPVGSGVYRLHQG 466
G P P G P PPPP +G P G GPPP P G +Q
Sbjct: 34 GKPEGRRPQGGNQPQRTPPPPGKPEGRPPQGGNQSQGPPPRPGKPEGPPPQGG----NQS 89
Query: 467 KGMMPPPPMGMMPPPPPPPSG---QPPPP----PSGPLPPWQQQQQQPPP------PPPP 513
+G PPP P PP G Q PPP P GP P Q Q PPP PPP
Sbjct: 90 QG---PPPRPGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPP 146
Query: 514 SSSMASSTPLP 524
S P P
Sbjct: 147 QGGNQSQGPPP 157
>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
preproprotein [Homo sapiens]
Length = 331
Score = 89.7 bits (221), Expect = 6e-18
Identities = 82/265 (30%), Positives = 97/265 (36%), Gaps = 46/265 (17%)
Query: 311 KEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMN 370
+E SL+A + P P GP P P N P P Q PP +
Sbjct: 26 EESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGD 85
Query: 371 SGPSESRPYHGMHGGGPGGP---GGGPHSFPHPLPSLTGGHGGHPMQ--HNPNGPPPPWM 425
S P G P GP GG P P P G G P Q + P GPPPP
Sbjct: 86 KSRSPRSP-----PGKPQGPPPQGGNQPQGPPPPP---GKPQGPPPQGGNRPQGPPPPGK 137
Query: 426 QPPPPPM---NQGPH-PPGH-HGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPP 480
PPP ++ P PPG GPPP G+ P G GK PPP G P
Sbjct: 138 PQGPPPQGDKSRSPRSPPGKPQGPPPQG---GNQPQGPPP---PPGKPQGPPPQGGKKPQ 191
Query: 481 PPPPP---------------SGQPPPPPSGPLPPWQQQQQQPPP-------PPPPSSSMA 518
PPPP S PP P GP P Q Q PPP PPP +
Sbjct: 192 GPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKP 251
Query: 519 SSTPLPWQQRSLPAAAMARAMRVRT 543
P P + + PA +++ R+
Sbjct: 252 QGPPPPGKPQGPPAQGGSKSQSARS 276
Score = 76.3 bits (186), Expect = 7e-14
Identities = 71/218 (32%), Positives = 82/218 (37%), Gaps = 40/218 (18%)
Query: 336 ATTPLASAPRPAAPANNPPPPSLMSTTQSRP-PWMNSGPSESRPYHGMHGGGPGGPGGGP 394
A L+SA + PSL++ P P + P P G G P G P
Sbjct: 9 ALLALSSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKP 68
Query: 395 HSFPHPLPSLTGGHGGHPMQ----HNPNGPPPPWM------------QPPPPPMNQGPHP 438
P P G G P Q +P PP PPPP QGP P
Sbjct: 69 QGPPPP-----GKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP 123
Query: 439 PGHH---GPPPMDQYLGSTPVG--SGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQP--PP 491
G + GPPP + G P G S R GK PPP G P PPPP G+P PP
Sbjct: 124 QGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP 183
Query: 492 PPSGPLPPWQQQQQQPPPP-----PPPSSSMASSTPLP 524
P G P Q PPPP PPP + S+ P
Sbjct: 184 PQGGKKP------QGPPPPGKPQGPPPQGDKSRSSQSP 215
Score = 74.7 bits (182), Expect = 2e-13
Identities = 77/270 (28%), Positives = 89/270 (32%), Gaps = 57/270 (21%)
Query: 297 PGDPQSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTP------------LASAP 344
PG PQ + + S + + P P GP P P
Sbjct: 74 PGKPQGPPPQGDKSRSPRSPPGK-PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGP 132
Query: 345 RPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPL--- 401
P PPP S + PP GP P G GP P G P P P
Sbjct: 133 PPPGKPQGPPPQGDKSRSPRSPPGKPQGPP---PQGGNQPQGPPPPPGKPQG-PPPQGGK 188
Query: 402 ----PSLTGGHGGHPMQHN-----------PNGPPP-----PWMQPPPPPMNQGPHPPGH 441
P G G P Q + P GPPP P PPPP QGP P G
Sbjct: 189 KPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG 248
Query: 442 H---GPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLP 498
+ GPPP + G G + + PP PP + Q PPPP+G P
Sbjct: 249 NKPQGPPPPGKPQGPPAQGGS-----KSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNP 303
Query: 499 PWQQQQQQPP------PPPPPSSSMASSTP 522
QQ Q PP PP PP S P
Sbjct: 304 ---QQPQAPPAGQPQGPPRPPQGGRPSRPP 330
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 89.4 bits (220), Expect = 8e-18
Identities = 77/216 (35%), Positives = 84/216 (38%), Gaps = 44/216 (20%)
Query: 344 PRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPL-- 401
P P PPP S + PP GP P G GP P G P P P
Sbjct: 92 PPPPGKPQGPPPQGDKSRSPRSPPGKPQGPP---PQGGNQPQGPPPPPGKPQG-PPPQGG 147
Query: 402 -----PSLTGGHGGHPMQHN------------PNGPPP-----PWMQPPPPPMNQGPHPP 439
P G G P Q + P GPPP P PPPP QGP P
Sbjct: 148 NKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ 207
Query: 440 GHH---GPPPMDQYLGSTPVG---SGVYRLHQGKGMMPPPPMGMMP--PPPPPPSGQPPP 491
G + GPPP + G P G S R GK PPP G P PPPPP Q PP
Sbjct: 208 GGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP 267
Query: 492 P-----PSGPLPPWQQQQQQPPPPPPPSSSMASSTP 522
P P GP PP + Q PPP S S +S +P
Sbjct: 268 PQGGNKPQGPPPP---GKPQGPPPQGGSKSRSSRSP 300
Score = 89.4 bits (220), Expect = 8e-18
Identities = 79/238 (33%), Positives = 89/238 (37%), Gaps = 52/238 (21%)
Query: 322 EAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHG 381
+ P P GP P P P PP S + PP GP P G
Sbjct: 140 QGPPPQGGNKPQGP--------PPPGKPQGPPPQGDNKSRSSRSPPGKPQGPP---PQGG 188
Query: 382 MHGGGPGGPGGGPHSFPHPL-------PSLTGGHGGHPMQHN------------PNGPPP 422
GP P G P P P P G G P Q + P GPPP
Sbjct: 189 NQPQGPPPPPGKPQG-PPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPP 247
Query: 423 -----PWMQPPPPPMNQGPHPPGHH---GPPPMDQYLGSTPVGSGVYRLHQ---GKGMMP 471
P PPPP QGP P G + GPPP + G P G R + GK P
Sbjct: 248 QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGP 307
Query: 472 PPPMGMMP--PPPPPPSGQPPPP-----PSGPLPPWQQQQQQPPPPPPPSSSMASSTP 522
PP G P PPPPP Q PPP P GP PP + Q PPP S S ++ +P
Sbjct: 308 PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPP---GKPQGPPPQGGSKSRSARSP 362
Score = 88.6 bits (218), Expect = 1e-17
Identities = 76/210 (36%), Positives = 83/210 (39%), Gaps = 29/210 (13%)
Query: 340 LASAPRPAAP--ANNPP-PPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHS 396
+A P+ A P N P PPS Q PP + P P G G P G P
Sbjct: 32 IAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQG 91
Query: 397 FPHPL----PSLTGGHGGHPMQH--NPNGPPP-----PWMQPPPPPMNQGPHPPGHH--- 442
P P P G P P GPPP P PPPP QGP P G +
Sbjct: 92 PPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQ 151
Query: 443 GPPPMDQYLGSTPVGSGVYRLHQ---GKGMMPPPPMGMMP--PPPPPPSGQPPPP----- 492
GPPP + G P G R + GK PPP G P PPPPP Q PPP
Sbjct: 152 GPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNK 211
Query: 493 PSGPLPPWQQQQQQPPPPPPPSSSMASSTP 522
P GP PP + Q PPP S A S P
Sbjct: 212 PQGPPPP--GKPQGPPPQGDNKSQSARSPP 239
Score = 85.5 bits (210), Expect = 1e-16
Identities = 80/278 (28%), Positives = 95/278 (34%), Gaps = 42/278 (15%)
Query: 297 PGDPQSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPP 356
PG PQ + + S + + P P GP P P N P P
Sbjct: 95 PGKPQGPPPQGDKSRSPRSPPGK-PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGP 153
Query: 357 SLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQ-- 414
Q PP ++ SR G G P G P P P G G P Q
Sbjct: 154 PPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPP----PGKPQGPPPQGG 209
Query: 415 HNPNGPPPPWMQPPPPPMNQGPH-----PPGH-HGPPPMDQYLGSTPVGSGVYRLHQGKG 468
+ P GPPPP PPP PPG GPPP G+ P G GK
Sbjct: 210 NKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQG---GNQPQGPPP---PPGKP 263
Query: 469 MMPPPPMGMMPPPPPPPS-GQPPPP---------------PSGPLPPWQQQQQQPPP--- 509
PPP G P PPPP Q PPP P GP P Q Q PPP
Sbjct: 264 QGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPG 323
Query: 510 ----PPPPSSSMASSTPLPWQQRSLPAAAMARAMRVRT 543
PPP + P P + + P +++ R+
Sbjct: 324 KPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARS 361
Score = 79.3 bits (194), Expect = 8e-15
Identities = 60/169 (35%), Positives = 70/169 (41%), Gaps = 27/169 (15%)
Query: 363 QSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPP 422
+ P + P + P G GP P G P P GG+ P GPPP
Sbjct: 26 EESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQG-----PPPQGGN-------QPQGPPP 73
Query: 423 PWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVG--SGVYRLHQGKGMMPPPPMGMMP- 479
P +P PP G P GPPP + G P G S R GK PPP G P
Sbjct: 74 PPGKPQGPPPQGGNKP---QGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQ 130
Query: 480 -PPPPPPSGQPPPP-----PSGPLPPWQQQQQQPPPPPPPSSSMASSTP 522
PPPPP Q PPP P GP PP + Q PPP + S +S +P
Sbjct: 131 GPPPPPGKPQGPPPQGGNKPQGPPPP---GKPQGPPPQGDNKSRSSRSP 176
Score = 77.4 bits (189), Expect = 3e-14
Identities = 71/233 (30%), Positives = 81/233 (34%), Gaps = 51/233 (21%)
Query: 322 EAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHG 381
+ P P GP P P P PP S + PP GP P G
Sbjct: 202 QGPPPQGGNKPQGP--------PPPGKPQGPPPQGDNKSQSARSPPGKPQGPP---PQGG 250
Query: 382 MHGGGPGGPGGGPHSFPH---------PLPSLTGG---HGGHPMQHN------PNGPPP- 422
GP P G P P P P G GG + + P GPPP
Sbjct: 251 NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQ 310
Query: 423 ----PWMQPPPPPMNQGPHPPGHH---GPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPM 475
P PPPP QGP P G + GPPP + G P G + + PP
Sbjct: 311 GGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGS-----KSRSARSPPGK 365
Query: 476 GMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPP------PPPPPSSSMASSTP 522
PP + Q PPPP+G P QQ Q PP PP PP S P
Sbjct: 366 PQGPPQQEGNNPQGPPPPAGGNP---QQPQAPPAGQPQGPPRPPQGGRPSRPP 415
Score = 62.0 bits (149), Expect = 1e-09
Identities = 50/147 (34%), Positives = 53/147 (36%), Gaps = 44/147 (29%)
Query: 402 PSLTGGHG-GHPMQ--HNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGS 458
PSL G+ G P Q + P GPP P +P PP G P G PP
Sbjct: 29 PSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPP------------- 75
Query: 459 GVYRLHQGKGMMPPPPMGMMPPPPPPPSG-QPPPP--------------PSGPLPPWQQQ 503
GK PPP G P PPPP Q PPP P GP P Q
Sbjct: 76 -------GKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQ 128
Query: 504 QQQPPPP------PPPSSSMASSTPLP 524
Q PPPP PPP P P
Sbjct: 129 PQGPPPPPGKPQGPPPQGGNKPQGPPP 155
>gi|18959210 WIRE protein [Homo sapiens]
Length = 440
Score = 89.0 bits (219), Expect = 1e-17
Identities = 75/260 (28%), Positives = 101/260 (38%), Gaps = 50/260 (19%)
Query: 298 GDPQSAQDKARMDKEYLSLMAE--LGEAPVPASVGSTSGPATTPLASAPRPAAPANNPPP 355
G PQ D +R L M L + P + ST ++ P P AN PP
Sbjct: 132 GRPQDDTDSSRASLPELPRMQRPSLPDLSRPNTTSSTGMKHSSSAPPPPPPGRRANAPPT 191
Query: 356 PSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQH 415
P M ++++ P + P P +H G G P P P ++ G G +
Sbjct: 192 PLPMHSSKA-PAYNREKPLPPTPGQRLHPGREGPPAPPPVKPPPSPVNIRTGPSGQSLAP 250
Query: 416 NPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQG--KGMMPPP 473
PPPP+ QPP P GP P + P + Q S ++R G +G+ PPP
Sbjct: 251 ----PPPPYRQPPGVP--NGPSSPTNESAPELPQRHNS------LHRKTPGPVRGLAPPP 298
Query: 474 PMGMMP--------------------PPPPPP-----SGQPPPPPSGPLPPWQQQQQQPP 508
P P PPPPPP + PPPP PP++ +PP
Sbjct: 299 PTSASPSLLSNRPPPPARDPPSRGAAPPPPPPVIRNGARDAPPPP----PPYRMHGSEPP 354
Query: 509 ----PPPPPSSSMASSTPLP 524
PPPPPS + A P P
Sbjct: 355 SRGKPPPPPSRTPAGPPPPP 374
Score = 57.8 bits (138), Expect = 3e-08
Identities = 62/222 (27%), Positives = 80/222 (36%), Gaps = 66/222 (29%)
Query: 341 ASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPH- 399
A+APRP A + P ++++ P + P RP S P
Sbjct: 120 AAAPRPPVSAASGRPQDDTDSSRASLPEL---PRMQRP-----------------SLPDL 159
Query: 400 PLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHP-PGHHGPPPMDQYLGSTPVGS 458
P+ T G M+H+ + PPPP PP N P P P H P P
Sbjct: 160 SRPNTTSSTG---MKHSSSAPPPP---PPGRRANAPPTPLPMHSSKAPAYNREKPLPPTP 213
Query: 459 GVYRLHQGKGMMPPPPMGMMPP----------------PPPPPSGQPPPPPSGPLPPWQQ 502
G RLH G+ P PP + PP PPPPP QPP P+GP P +
Sbjct: 214 G-QRLHPGREGPPAPPP-VKPPPSPVNIRTGPSGQSLAPPPPPYRQPPGVPNGPSSPTNE 271
Query: 503 QQQQ--------------------PPPPPPPSSSMASSTPLP 524
+ PPPP S S+ S+ P P
Sbjct: 272 SAPELPQRHNSLHRKTPGPVRGLAPPPPTSASPSLLSNRPPP 313
Score = 36.2 bits (82), Expect = 0.080
Identities = 12/15 (80%), Positives = 13/15 (86%)
Query: 478 MPPPPPPPSGQPPPP 492
+PPPPPPP G PPPP
Sbjct: 3 IPPPPPPPPGPPPPP 17
Score = 35.8 bits (81), Expect = 0.10
Identities = 32/111 (28%), Positives = 38/111 (34%), Gaps = 23/111 (20%)
Query: 330 GSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGG 389
G G A P SA P+ +N PPPP+ PP + P P + G
Sbjct: 289 GPVRGLAPPPPTSAS-PSLLSNRPPPPA------RDPPSRGAAPPPPPPV--IRNGARDA 339
Query: 390 PGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWM-----QPPPPPMNQG 435
P P P HG P PPP PPPPP+ G
Sbjct: 340 P---------PPPPPYRMHGSEPPSRGKPPPPPSRTPAGPPPPPPPPLRNG 381
Score = 33.5 bits (75), Expect = 0.52
Identities = 19/60 (31%), Positives = 24/60 (40%), Gaps = 3/60 (5%)
Query: 473 PPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQRSLPA 532
P + M P P +P S + + PPPPPP + A TPLP PA
Sbjct: 146 PELPRMQRPSLPDLSRPNTTSSTGM---KHSSSAPPPPPPGRRANAPPTPLPMHSSKAPA 202
Score = 33.1 bits (74), Expect = 0.67
Identities = 13/20 (65%), Positives = 15/20 (75%), Gaps = 2/20 (10%)
Query: 475 MGMMPPPPPPPSGQPPPPPS 494
M + PPPPPPP PPPPP+
Sbjct: 1 MPIPPPPPPPPG--PPPPPT 18
Score = 30.8 bits (68), Expect = 3.3
Identities = 15/32 (46%), Positives = 15/32 (46%), Gaps = 5/32 (15%)
Query: 478 MPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPP 509
MP PPPPP PPP P PP Q P
Sbjct: 1 MPIPPPPP-----PPPGPPPPPTFHQANTEQP 27
>gi|11386183 WAS protein family, member 2 [Homo sapiens]
Length = 498
Score = 88.6 bits (218), Expect = 1e-17
Identities = 74/258 (28%), Positives = 95/258 (36%), Gaps = 68/258 (26%)
Query: 305 DKARMDKEYLSLMAELGEAPVPASVGSTSG---------------PATTPLASAPRPAAP 349
+K +M +E++ +LG + P ++ +G P + AS+P P+
Sbjct: 204 EKMKMGQEFVESKEKLGTSGYPPTLVYQNGSIGCVENVDASSYPPPPQSDSASSPSPSFS 263
Query: 350 ANNPPPPSLMSTTQSRPPWMNSGPSE-SRPYHGMHGGGPGGPGGGP---HSFPHPLPSLT 405
+N PPP P+E S P G G GP S P P P L
Sbjct: 264 EDNLPPP----------------PAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAPPLG 307
Query: 406 GGHGGHPMQHNPNGPPPP-----WMQPPPPPMNQG----PHPPGHHGPPPMDQYLGSTPV 456
G P P PPPP + PPPPP+ G P PP PP + P
Sbjct: 308 SPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPP 367
Query: 457 GSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQP----------PPPPSGPLPPWQQQQQQ 506
PPPP P PPPP QP PPPP P PP+ Q
Sbjct: 368 --------------PPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPGPPPPPFTGADGQ 413
Query: 507 PPPPPPPSSSMASSTPLP 524
P PPP S + + LP
Sbjct: 414 PAIPPPLSDTTKPKSSLP 431
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 86.7 bits (213), Expect = 5e-17
Identities = 77/223 (34%), Positives = 94/223 (42%), Gaps = 34/223 (15%)
Query: 324 PVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMH 383
P+P + S+S P L P P P P+L ST +PP + P +
Sbjct: 860 PLPCTESSSSMPG---LGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLP 916
Query: 384 GGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQ---PPPPPMNQG--PHP 438
G G P P + PLP L G G P PPPP PPPPP+ P P
Sbjct: 917 GAGIPPPPPLPGAGILPLPPLPGA--GIP-------PPPPLPGAAIPPPPPLPGAGIPLP 967
Query: 439 PGHHG----PPPMDQYLGSTPV----GSGVYRLHQ--GKGMMPPPPM---GMMPPPPPPP 485
P G PPP G P G+G+ G G+ PPPP+ G+ PPPP P
Sbjct: 968 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1027
Query: 486 SGQPPPPP----SGPLPPWQQQQQQPPPPPPPSSSMASSTPLP 524
+G PPPPP P PP PPPPP P + + PLP
Sbjct: 1028 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1070
Score = 83.6 bits (205), Expect = 4e-16
Identities = 74/222 (33%), Positives = 90/222 (40%), Gaps = 38/222 (17%)
Query: 324 PVPASVGSTSGPATTPLASA----PRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPY 379
P+P + P PL A P P A PPPP L PP + P
Sbjct: 965 PLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP- 1023
Query: 380 HGMHGGG----PGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQ----PPPPP 431
+ G G P PG G P P P G P PPPP + PPPPP
Sbjct: 1024 -PLPGAGIPPPPPLPGAG---IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1079
Query: 432 MNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQ--GKGMMPPPPM---GMMPPPPPPPS 486
+ PP PPP+ G+G+ G G+ PPPP+ G+ PPPP P +
Sbjct: 1080 LPGAGIPP----PPPLP--------GAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGA 1127
Query: 487 GQPPPPP--SG--PLPPWQQQQQQPPPPPPPSSSMASSTPLP 524
G PPPPP P PP + PPPPP P + + PLP
Sbjct: 1128 GIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLP 1169
Score = 79.3 bits (194), Expect = 8e-15
Identities = 76/233 (32%), Positives = 89/233 (38%), Gaps = 45/233 (19%)
Query: 324 PVPASVGSTSGPATTPLASA----PRPAAPANNPPPPSLMST-TQSRPPWMNSGPSESRP 378
P P + P PL A P P A PPPP L PP +G P
Sbjct: 1042 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1101
Query: 379 YHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNG---PPPPWMQ---PPPPPM 432
G+ P G P PLP G G P P PPPP + PPPPP+
Sbjct: 1102 LPGVGIPPPPPLPGAGIPPPPPLP----GAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPL 1157
Query: 433 NQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQ--GKGMMPPPPM---GMMPPPPPPPSG 487
PP PPP+ G+G+ G G+ PPPP+ G+ PPPP P +G
Sbjct: 1158 PGAGIPP----PPPLP--------GAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAG 1205
Query: 488 QPPPP-------PSGPLPPWQQQQQQPPPPP------PPSSSMASSTPLPWQQ 527
PPPP P P PP PPPP PP S+ LP Q
Sbjct: 1206 IPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQ 1258
Score = 79.0 bits (193), Expect = 1e-14
Identities = 76/240 (31%), Positives = 89/240 (37%), Gaps = 47/240 (19%)
Query: 324 PVPASVGSTSGPATTPLASA----PRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPY 379
P P + P PL A P P A PPPP L PP + P
Sbjct: 998 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP- 1056
Query: 380 HGMHGGG----PGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQ----PPPPP 431
+ G G P PG G P P P G P PPPP + PPPPP
Sbjct: 1057 -PLPGAGIPPPPPLPGAG---IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPP 1112
Query: 432 MNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQ--GKGMMPPPPM---GMMPPPPPPPS 486
+ PP PPP+ G+G+ G G+ PPPP+ G+ PPPP P +
Sbjct: 1113 LPGAGIPP----PPPLP--------GAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGA 1160
Query: 487 GQPPPPPSG-----PLPPWQQQQQQPPPP--------PPPSSSMASSTPLPWQQRSLPAA 533
G PPPPP P PP PPPP PPP P P +P A
Sbjct: 1161 GIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPA 1220
Score = 65.5 bits (158), Expect = 1e-10
Identities = 57/189 (30%), Positives = 69/189 (36%), Gaps = 42/189 (22%)
Query: 353 PPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHP 412
PPPPSL+ + P S S + H + P P P P
Sbjct: 811 PPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPL--------P 862
Query: 413 MQHNPNGPPPPWMQPPPPPMNQGPHPPGHHG-----PPPMDQYLGSTPVGSGVYRLHQGK 467
+ + P M PPPPP G P PPP+ QG
Sbjct: 863 CTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPL-----------------QGT 905
Query: 468 GMMPPPPMGMMPPPPPPPSGQPPPPPSG-----PLPPWQQQQQQPPPPPPPSSSMASSTP 522
M+PPPP PP P +G PPPPP PLPP PPPPP P +++ P
Sbjct: 906 EMLPPPP------PPLPGAGIPPPPPLPGAGILPLPPLPGAGI-PPPPPLPGAAIPPPPP 958
Query: 523 LPWQQRSLP 531
LP LP
Sbjct: 959 LPGAGIPLP 967
Score = 58.9 bits (141), Expect = 1e-08
Identities = 51/169 (30%), Positives = 67/169 (39%), Gaps = 22/169 (13%)
Query: 378 PYHGMHGGGPGGPGG--GPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPP---M 432
P G+ G P PG GP + SL +Q + + P QPPPPP
Sbjct: 759 PVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPPSLLW 818
Query: 433 NQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPP------------MGMMPP 480
+ G PG P + ++ S + PPP +GM+PP
Sbjct: 819 SAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLGMVPP 878
Query: 481 PPPPPSGQPPPP-PSGPL---PPWQQQQQQPPPPPP-PSSSMASSTPLP 524
PPPP G P PS + PP Q + PPPPPP P + + PLP
Sbjct: 879 PPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLP 927
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 85.9 bits (211), Expect = 9e-17
Identities = 98/409 (23%), Positives = 147/409 (35%), Gaps = 68/409 (16%)
Query: 178 RGKGSVKEGKVGRK------DGQMLP--------GEDEPLHALVTANTM--ENVKKAVEQ 221
R +GS+ + GRK DG+ P G + P A ++N E VKK+ ++
Sbjct: 22 RSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKK 81
Query: 222 IRNILKQGIETPEDQNDLRKMQLRELARLNGTLREDDNRILRPWQSSETRSITNTTVCTK 281
++ +++ + Q + E R + + I RP SE ++ +
Sbjct: 82 VKEEASSPLKSNKRQREKVASDTEEADRTSSK-KTKTQEISRPNSPSEGEGESSDSRSVN 140
Query: 282 CGGAGH---IASDCKFQRPGDPQSAQDKARMD----KEYLSLMAELGEAPVPASVGSTSG 334
G+ I D + P P +++ D ++ L +AP + +S
Sbjct: 141 DEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSA 200
Query: 335 PATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYH------GMHGGGPG 388
P TP P P A PP S T S+ P P+ P+ +H P
Sbjct: 201 PPGTPQLPTPGPTPSATAVPPQG--SPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPP 258
Query: 389 GPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPP------PMNQGPHPPGHH 442
P PH PHP G G P + PP PP P P+ Q P PP
Sbjct: 259 SPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPF 318
Query: 443 GPPPMDQYLGSTPVGSGVYRLHQGKGM-------------------MPPPPMGM---MPP 480
G PP G P+G+ + + +PP P+ M PP
Sbjct: 319 GLPPQASQ-GQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPP 377
Query: 481 P-------PPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTP 522
P P P + + PP SGP P PPP P SS+++ P
Sbjct: 378 PTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHP 426
Score = 67.8 bits (164), Expect = 2e-11
Identities = 73/241 (30%), Positives = 88/241 (36%), Gaps = 54/241 (22%)
Query: 324 PVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMH 383
P P + + PL ++P A P + P+ S QS+ P P E +P
Sbjct: 315 PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQP-----PRE-QPL---- 364
Query: 384 GGGPGGPGGGPHSFPHP---LPSLTGGH---------GGHPMQHNPNGPPPPWMQPPPPP 431
P P PH P P +P L G P N N PPPP ++P
Sbjct: 365 ---PPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSL 421
Query: 432 MNQGPHPPGHHGPP----PMDQYLGSTPVGSGVYRLHQGKGMMPPP----PMGMMPPPPP 483
HPP H PP P Q L S+P L Q + + PPP P G+ P
Sbjct: 422 STH--HPPSAHPPPLQLMPQSQPLPSSPAQPP--GLTQSQNLPPPPASHPPTGLHQVAPQ 477
Query: 484 PPSGQPPPPPSGP---LPPWQQQQQQPPPPP-----PPSSSMA---------SSTPLPWQ 526
PP Q P P GP PP PP P PP S A SS PLP
Sbjct: 478 PPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTV 537
Query: 527 Q 527
Q
Sbjct: 538 Q 538
Score = 58.9 bits (141), Expect = 1e-08
Identities = 66/225 (29%), Positives = 79/225 (35%), Gaps = 61/225 (27%)
Query: 324 PVPASVGSTSGPATTPLASAPRPAAPANNP----PPPSLMSTTQSRPPWMNSGPSESRPY 379
P P ++ P TTP+ P P A + P P P M+ PP + P S
Sbjct: 366 PAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALK--PLSSLST 423
Query: 380 HGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPP--------PP 431
H P P S PLPS G + + N PPPP PP PP
Sbjct: 424 HHPPSAHPPPLQLMPQS--QPLPSSPAQPPG--LTQSQNLPPPPASHPPTGLHQVAPQPP 479
Query: 432 MNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPP 491
Q P PG GPPP+ TP P P PP P S QPP
Sbjct: 480 FAQHPFVPG--GPPPI------TP---------------PTCPSTSTPPAGPGTSAQPPC 516
Query: 492 P------------PSGPLPPWQQQQQ--------QPPPPPPPSSS 516
S PLP Q +++ + PPPPP S S
Sbjct: 517 SGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPS 561
Score = 50.8 bits (120), Expect = 3e-06
Identities = 56/216 (25%), Positives = 75/216 (34%), Gaps = 54/216 (25%)
Query: 300 PQSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLM 359
PQ +A +LS G +P + PA PL+S P+ +PPP LM
Sbjct: 383 PQLPAPQAHKHPPHLS-----GPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLM 437
Query: 360 STTQ------SRPPWMNSG-----PSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGH 408
+Q ++PP + P S P G+H P P
Sbjct: 438 PQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPP-----------------F 480
Query: 409 GGHPMQHNPNGPPPPWMQPPP-PPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGK 467
HP P GPPP + PP P + P PG PP G+ G + G
Sbjct: 481 AQHPFV--PGGPPP--ITPPTCPSTSTPPAGPGTSAQPPCS---GAAASGGSI----AGG 529
Query: 468 GMMPPPPMGMM---------PPPPPPPSGQPPPPPS 494
P P + + P PPPP P P P+
Sbjct: 530 SSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPT 565
Score = 36.6 bits (83), Expect = 0.061
Identities = 24/88 (27%), Positives = 30/88 (34%), Gaps = 11/88 (12%)
Query: 444 PPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQ 503
PP + G TP S PP +P P P PS PP P
Sbjct: 184 PPALQAPTGVTPAPSSA-----------PPGTPQLPTPGPTPSATAVPPQGSPTASQAPN 232
Query: 504 QQQPPPPPPPSSSMASSTPLPWQQRSLP 531
Q Q P P P + + + L Q+ P
Sbjct: 233 QPQAPTAPVPHTHIQQAPALHPQRPPSP 260
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 85.9 bits (211), Expect = 9e-17
Identities = 98/409 (23%), Positives = 147/409 (35%), Gaps = 68/409 (16%)
Query: 178 RGKGSVKEGKVGRK------DGQMLP--------GEDEPLHALVTANTM--ENVKKAVEQ 221
R +GS+ + GRK DG+ P G + P A ++N E VKK+ ++
Sbjct: 576 RSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKK 635
Query: 222 IRNILKQGIETPEDQNDLRKMQLRELARLNGTLREDDNRILRPWQSSETRSITNTTVCTK 281
++ +++ + Q + E R + + I RP SE ++ +
Sbjct: 636 VKEEASSPLKSNKRQREKVASDTEEADRTSSK-KTKTQEISRPNSPSEGEGESSDSRSVN 694
Query: 282 CGGAGH---IASDCKFQRPGDPQSAQDKARMD----KEYLSLMAELGEAPVPASVGSTSG 334
G+ I D + P P +++ D ++ L +AP + +S
Sbjct: 695 DEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSA 754
Query: 335 PATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYH------GMHGGGPG 388
P TP P P A PP S T S+ P P+ P+ +H P
Sbjct: 755 PPGTPQLPTPGPTPSATAVPPQG--SPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPP 812
Query: 389 GPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPP------PMNQGPHPPGHH 442
P PH PHP G G P + PP PP P P+ Q P PP
Sbjct: 813 SPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPF 872
Query: 443 GPPPMDQYLGSTPVGSGVYRLHQGKGM-------------------MPPPPMGM---MPP 480
G PP G P+G+ + + +PP P+ M PP
Sbjct: 873 GLPPQASQ-GQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPP 931
Query: 481 P-------PPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTP 522
P P P + + PP SGP P PPP P SS+++ P
Sbjct: 932 PTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHP 980
Score = 67.8 bits (164), Expect = 2e-11
Identities = 73/241 (30%), Positives = 88/241 (36%), Gaps = 54/241 (22%)
Query: 324 PVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMH 383
P P + + PL ++P A P + P+ S QS+ P P E +P
Sbjct: 869 PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQP-----PRE-QPL---- 918
Query: 384 GGGPGGPGGGPHSFPHP---LPSLTGGH---------GGHPMQHNPNGPPPPWMQPPPPP 431
P P PH P P +P L G P N N PPPP ++P
Sbjct: 919 ---PPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSL 975
Query: 432 MNQGPHPPGHHGPP----PMDQYLGSTPVGSGVYRLHQGKGMMPPP----PMGMMPPPPP 483
HPP H PP P Q L S+P L Q + + PPP P G+ P
Sbjct: 976 STH--HPPSAHPPPLQLMPQSQPLPSSPAQPP--GLTQSQNLPPPPASHPPTGLHQVAPQ 1031
Query: 484 PPSGQPPPPPSGP---LPPWQQQQQQPPPPP-----PPSSSMA---------SSTPLPWQ 526
PP Q P P GP PP PP P PP S A SS PLP
Sbjct: 1032 PPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTV 1091
Query: 527 Q 527
Q
Sbjct: 1092 Q 1092
Score = 58.9 bits (141), Expect = 1e-08
Identities = 66/225 (29%), Positives = 79/225 (35%), Gaps = 61/225 (27%)
Query: 324 PVPASVGSTSGPATTPLASAPRPAAPANNP----PPPSLMSTTQSRPPWMNSGPSESRPY 379
P P ++ P TTP+ P P A + P P P M+ PP + P S
Sbjct: 920 PAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALK--PLSSLST 977
Query: 380 HGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPP--------PP 431
H P P S PLPS G + + N PPPP PP PP
Sbjct: 978 HHPPSAHPPPLQLMPQS--QPLPSSPAQPPG--LTQSQNLPPPPASHPPTGLHQVAPQPP 1033
Query: 432 MNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPP 491
Q P PG GPPP+ TP P P PP P S QPP
Sbjct: 1034 FAQHPFVPG--GPPPI------TP---------------PTCPSTSTPPAGPGTSAQPPC 1070
Query: 492 P------------PSGPLPPWQQQQQ--------QPPPPPPPSSS 516
S PLP Q +++ + PPPPP S S
Sbjct: 1071 SGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPS 1115
Score = 50.8 bits (120), Expect = 3e-06
Identities = 56/216 (25%), Positives = 75/216 (34%), Gaps = 54/216 (25%)
Query: 300 PQSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLM 359
PQ +A +LS G +P + PA PL+S P+ +PPP LM
Sbjct: 937 PQLPAPQAHKHPPHLS-----GPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLM 991
Query: 360 STTQ------SRPPWMNSG-----PSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGH 408
+Q ++PP + P S P G+H P P
Sbjct: 992 PQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPP-----------------F 1034
Query: 409 GGHPMQHNPNGPPPPWMQPPP-PPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGK 467
HP P GPPP + PP P + P PG PP G+ G + G
Sbjct: 1035 AQHPFV--PGGPPP--ITPPTCPSTSTPPAGPGTSAQPPCS---GAAASGGSI----AGG 1083
Query: 468 GMMPPPPMGMM---------PPPPPPPSGQPPPPPS 494
P P + + P PPPP P P P+
Sbjct: 1084 SSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPT 1119
Score = 36.6 bits (83), Expect = 0.061
Identities = 24/88 (27%), Positives = 30/88 (34%), Gaps = 11/88 (12%)
Query: 444 PPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQ 503
PP + G TP S PP +P P P PS PP P
Sbjct: 738 PPALQAPTGVTPAPSSA-----------PPGTPQLPTPGPTPSATAVPPQGSPTASQAPN 786
Query: 504 QQQPPPPPPPSSSMASSTPLPWQQRSLP 531
Q Q P P P + + + L Q+ P
Sbjct: 787 QPQAPTAPVPHTHIQQAPALHPQRPPSP 814
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 85.9 bits (211), Expect = 9e-17
Identities = 98/409 (23%), Positives = 147/409 (35%), Gaps = 68/409 (16%)
Query: 178 RGKGSVKEGKVGRK------DGQMLP--------GEDEPLHALVTANTM--ENVKKAVEQ 221
R +GS+ + GRK DG+ P G + P A ++N E VKK+ ++
Sbjct: 576 RSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKK 635
Query: 222 IRNILKQGIETPEDQNDLRKMQLRELARLNGTLREDDNRILRPWQSSETRSITNTTVCTK 281
++ +++ + Q + E R + + I RP SE ++ +
Sbjct: 636 VKEEASSPLKSNKRQREKVASDTEEADRTSSK-KTKTQEISRPNSPSEGEGESSDSRSVN 694
Query: 282 CGGAGH---IASDCKFQRPGDPQSAQDKARMD----KEYLSLMAELGEAPVPASVGSTSG 334
G+ I D + P P +++ D ++ L +AP + +S
Sbjct: 695 DEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSA 754
Query: 335 PATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYH------GMHGGGPG 388
P TP P P A PP S T S+ P P+ P+ +H P
Sbjct: 755 PPGTPQLPTPGPTPSATAVPPQG--SPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPP 812
Query: 389 GPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPP------PMNQGPHPPGHH 442
P PH PHP G G P + PP PP P P+ Q P PP
Sbjct: 813 SPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPF 872
Query: 443 GPPPMDQYLGSTPVGSGVYRLHQGKGM-------------------MPPPPMGM---MPP 480
G PP G P+G+ + + +PP P+ M PP
Sbjct: 873 GLPPQASQ-GQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPP 931
Query: 481 P-------PPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTP 522
P P P + + PP SGP P PPP P SS+++ P
Sbjct: 932 PTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHP 980
Score = 67.8 bits (164), Expect = 2e-11
Identities = 73/241 (30%), Positives = 88/241 (36%), Gaps = 54/241 (22%)
Query: 324 PVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMH 383
P P + + PL ++P A P + P+ S QS+ P P E +P
Sbjct: 869 PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQP-----PRE-QPL---- 918
Query: 384 GGGPGGPGGGPHSFPHP---LPSLTGGH---------GGHPMQHNPNGPPPPWMQPPPPP 431
P P PH P P +P L G P N N PPPP ++P
Sbjct: 919 ---PPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSL 975
Query: 432 MNQGPHPPGHHGPP----PMDQYLGSTPVGSGVYRLHQGKGMMPPP----PMGMMPPPPP 483
HPP H PP P Q L S+P L Q + + PPP P G+ P
Sbjct: 976 STH--HPPSAHPPPLQLMPQSQPLPSSPAQPP--GLTQSQNLPPPPASHPPTGLHQVAPQ 1031
Query: 484 PPSGQPPPPPSGP---LPPWQQQQQQPPPPP-----PPSSSMA---------SSTPLPWQ 526
PP Q P P GP PP PP P PP S A SS PLP
Sbjct: 1032 PPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTV 1091
Query: 527 Q 527
Q
Sbjct: 1092 Q 1092
Score = 58.9 bits (141), Expect = 1e-08
Identities = 66/225 (29%), Positives = 79/225 (35%), Gaps = 61/225 (27%)
Query: 324 PVPASVGSTSGPATTPLASAPRPAAPANNP----PPPSLMSTTQSRPPWMNSGPSESRPY 379
P P ++ P TTP+ P P A + P P P M+ PP + P S
Sbjct: 920 PAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALK--PLSSLST 977
Query: 380 HGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPP--------PP 431
H P P S PLPS G + + N PPPP PP PP
Sbjct: 978 HHPPSAHPPPLQLMPQS--QPLPSSPAQPPG--LTQSQNLPPPPASHPPTGLHQVAPQPP 1033
Query: 432 MNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPP 491
Q P PG GPPP+ TP P P PP P S QPP
Sbjct: 1034 FAQHPFVPG--GPPPI------TP---------------PTCPSTSTPPAGPGTSAQPPC 1070
Query: 492 P------------PSGPLPPWQQQQQ--------QPPPPPPPSSS 516
S PLP Q +++ + PPPPP S S
Sbjct: 1071 SGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPS 1115
Score = 50.8 bits (120), Expect = 3e-06
Identities = 56/216 (25%), Positives = 75/216 (34%), Gaps = 54/216 (25%)
Query: 300 PQSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLM 359
PQ +A +LS G +P + PA PL+S P+ +PPP LM
Sbjct: 937 PQLPAPQAHKHPPHLS-----GPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLM 991
Query: 360 STTQ------SRPPWMNSG-----PSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGH 408
+Q ++PP + P S P G+H P P
Sbjct: 992 PQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPP-----------------F 1034
Query: 409 GGHPMQHNPNGPPPPWMQPPP-PPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGK 467
HP P GPPP + PP P + P PG PP G+ G + G
Sbjct: 1035 AQHPFV--PGGPPP--ITPPTCPSTSTPPAGPGTSAQPPCS---GAAASGGSI----AGG 1083
Query: 468 GMMPPPPMGMM---------PPPPPPPSGQPPPPPS 494
P P + + P PPPP P P P+
Sbjct: 1084 SSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPT 1119
Score = 36.6 bits (83), Expect = 0.061
Identities = 24/88 (27%), Positives = 30/88 (34%), Gaps = 11/88 (12%)
Query: 444 PPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQ 503
PP + G TP S PP +P P P PS PP P
Sbjct: 738 PPALQAPTGVTPAPSSA-----------PPGTPQLPTPGPTPSATAVPPQGSPTASQAPN 786
Query: 504 QQQPPPPPPPSSSMASSTPLPWQQRSLP 531
Q Q P P P + + + L Q+ P
Sbjct: 787 QPQAPTAPVPHTHIQQAPALHPQRPPSP 814
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 84.0 bits (206), Expect = 3e-16
Identities = 78/235 (33%), Positives = 93/235 (39%), Gaps = 49/235 (20%)
Query: 301 QSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANN----PPPP 356
Q + A++ KE E+ A S P+ P+ P P P ++ PPPP
Sbjct: 534 QLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVP--PAPPLPGDSGTIIPPPP 591
Query: 357 SLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHN 416
+ +T PP P P P PGG S P PSL GG
Sbjct: 592 APGDSTTPPPP-----PPPPPP-------PPPLPGGVCISSP---PSLPGG--------T 628
Query: 417 PNGPPPPWMQ----PPPPPMNQG---PHP---PGHHGPPPMDQYLGSTPVGSGVYRLHQG 466
PPPP PPPPP+ +G P P PG PP GS + L
Sbjct: 629 AISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGS 688
Query: 467 KGMMPPPP-----MGMMPPPPPPPSGQ----PPPPPSGP-LPPWQQQQQQPPPPP 511
G+ PPPP GM PPPPP P G PPP P GP +PP PPPPP
Sbjct: 689 AGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPP 743
Score = 46.6 bits (109), Expect = 6e-05
Identities = 41/116 (35%), Positives = 48/116 (41%), Gaps = 19/116 (16%)
Query: 324 PVPASVGSTSGPATTPLASAPRPAAP----ANNPPPPSLMSTTQSRPPWMNSGPSESRPY 379
P+P VG S P++ P +A P P A PPPP + + PP P E+
Sbjct: 647 PLPEGVGIPS-PSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEA--- 702
Query: 380 HGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQG 435
GM P PGG P P P GG G P PPP PPPPP G
Sbjct: 703 -GMPPPPPPLPGGPGIPPPPPFP---GGPGIPP-------PPPGMGMPPPPPFGFG 747
>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
Length = 1272
Score = 84.0 bits (206), Expect = 3e-16
Identities = 78/235 (33%), Positives = 93/235 (39%), Gaps = 49/235 (20%)
Query: 301 QSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANN----PPPP 356
Q + A++ KE E+ A S P+ P+ P P P ++ PPPP
Sbjct: 543 QLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVP--PAPPLPGDSGTIIPPPP 600
Query: 357 SLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHN 416
+ +T PP P P P PGG S P PSL GG
Sbjct: 601 APGDSTTPPPP-----PPPPPP-------PPPLPGGVCISSP---PSLPGG--------T 637
Query: 417 PNGPPPPWMQ----PPPPPMNQG---PHP---PGHHGPPPMDQYLGSTPVGSGVYRLHQG 466
PPPP PPPPP+ +G P P PG PP GS + L
Sbjct: 638 AISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGS 697
Query: 467 KGMMPPPP-----MGMMPPPPPPPSGQ----PPPPPSGP-LPPWQQQQQQPPPPP 511
G+ PPPP GM PPPPP P G PPP P GP +PP PPPPP
Sbjct: 698 AGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPP 752
Score = 46.6 bits (109), Expect = 6e-05
Identities = 41/116 (35%), Positives = 48/116 (41%), Gaps = 19/116 (16%)
Query: 324 PVPASVGSTSGPATTPLASAPRPAAP----ANNPPPPSLMSTTQSRPPWMNSGPSESRPY 379
P+P VG S P++ P +A P P A PPPP + + PP P E+
Sbjct: 656 PLPEGVGIPS-PSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEA--- 711
Query: 380 HGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQG 435
GM P PGG P P P GG G P PPP PPPPP G
Sbjct: 712 -GMPPPPPPLPGGPGIPPPPPFP---GGPGIPP-------PPPGMGMPPPPPFGFG 756
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 84.0 bits (206), Expect = 3e-16
Identities = 79/233 (33%), Positives = 92/233 (39%), Gaps = 46/233 (19%)
Query: 321 GEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPS--ESRP 378
G PVP S G SGP P P PP P + S S PP + S P +S P
Sbjct: 148 GRFPVP-SPGHRSGP--------PEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSP 198
Query: 379 YHGMHGGGPGG-----PGGGPHSFPHPLPSLTGG--------HGGHPMQHNPNGPPPPWM 425
++ PGG PG P FP + GG P + P PP P
Sbjct: 199 HNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSR 258
Query: 426 ----QPPPPPMNQGPHPPGHHG--PPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMP 479
+PPPPP G P H PPP Q PV S P P
Sbjct: 259 ALDDKPPPPPPPVGNRPSIHREAVPPPPPQN-NKPPVPS-----------TPRPSASSQA 306
Query: 480 PPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASST-PLPWQQRSLP 531
PPPPPP +P PP PLPP + P P + S++SST PLP RS P
Sbjct: 307 PPPPPPPSRPGPP---PLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGP 356
Score = 73.9 bits (180), Expect = 3e-13
Identities = 66/216 (30%), Positives = 78/216 (36%), Gaps = 26/216 (12%)
Query: 327 ASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGG 386
A+ + SG + PL + A PPS P SGP E P
Sbjct: 115 ANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPE--PQRNRMPPP 172
Query: 387 PGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPP 446
G P S P P+PS P HN PP P P P P PG+ G
Sbjct: 173 RPDVGSKPDSIPPPVPSTPRPIQSSP--HNRGSPPVPGGPRQPSPGPTPPPFPGNRGTAL 230
Query: 447 MDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMM---PPPPPPPSGQ---------PPPPPS 494
+ +P+ S + +PP P + PPPPPPP G PPPPP
Sbjct: 231 GGGSIRQSPLSSS--SPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQ 288
Query: 495 GPLPPW------QQQQQQPPPPPPPSSSMASSTPLP 524
PP Q PPPPPPP S PLP
Sbjct: 289 NNKPPVPSTPRPSASSQAPPPPPPP--SRPGPPPLP 322
Score = 73.9 bits (180), Expect = 3e-13
Identities = 75/251 (29%), Positives = 88/251 (35%), Gaps = 66/251 (26%)
Query: 324 PVPASVGSTSGPATTPLASAPRP--AAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHG 381
P VGS P+ S PRP ++P N PP Q P GP+ P+ G
Sbjct: 171 PPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSP-----GPTPP-PFPG 224
Query: 382 MHGGGPGG--------PGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQ------- 426
G GG P S PLP + P PPPP
Sbjct: 225 NRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPS----RALDDKPPPPPPPVGNRPSIHRE 280
Query: 427 --PPPPPMNQGPH------------------PPGHHGPPPMDQYLGSTPVGSGVYRLHQ- 465
PPPPP N P PP GPPP+ S+ RL Q
Sbjct: 281 AVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPP---SSSGNDETPRLPQR 337
Query: 466 ----GKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASST 521
P P G P PPPPS +PPPP P + P PPPPP S S++
Sbjct: 338 NLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDP-----PGRSGPLPPPPPVSRNGSTS 392
Query: 522 PLPWQQRSLPA 532
R+LPA
Sbjct: 393 ------RALPA 397
Score = 40.8 bits (94), Expect = 0.003
Identities = 45/189 (23%), Positives = 61/189 (32%), Gaps = 31/189 (16%)
Query: 328 SVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGP 387
S+ S++ P +P S P P P+ PPPP R P SGP P +G
Sbjct: 340 SLSSSTPPLPSPGRSGPLPPPPSERPPPPV-------RDPPGRSGPLPPPPPVSRNGSTS 392
Query: 388 GGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPM 447
P LPS +G P P P PPPP G P
Sbjct: 393 RALPATPQ-----LPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGFQDSPCE 447
Query: 448 DQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPP---PPSGQPPPPPSGPLPPWQQQQ 504
D++ + H P+ +PPP P P ++
Sbjct: 448 DEW-------ESRFYFH---------PISDLPPPEPYVQTTKSYPSKLARNESRSGSNRR 491
Query: 505 QQPPPPPPP 513
++ PP PP
Sbjct: 492 ERGAPPLPP 500
Score = 39.3 bits (90), Expect = 0.009
Identities = 52/220 (23%), Positives = 66/220 (30%), Gaps = 56/220 (25%)
Query: 346 PAAPANNPPPPSLMSTTQSRPPWMN----------------------------SGPSESR 377
P P PPPP + + P +N S P +
Sbjct: 2 PVPPPPAPPPPPTFALANTEKPTLNKTEQAGRNALLSDISKGKKLKKTVTNDRSAPILDK 61
Query: 378 PYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPP--PWMQPPPPPMNQG 435
P GGG GG GGG GG GG GPP Q P +
Sbjct: 62 PKGAGAGGGGGGFGGGGGFGG-------GGGGGGGGSFGGGGPPGLGGLFQAGMPKLRST 114
Query: 436 PHPPGHHGP--PPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPP 493
+ G PP+ P G R K PP G P P P PP P
Sbjct: 115 ANRDNDSGGSRPPL------LPPGG---RSTSAKPFSPPSGPGRFPVPSPGHRSGPPEP- 164
Query: 494 SGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQRSLPAA 533
Q+ + PP P S + P+P R + ++
Sbjct: 165 -------QRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSS 197
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 84.0 bits (206), Expect = 3e-16
Identities = 79/233 (33%), Positives = 92/233 (39%), Gaps = 46/233 (19%)
Query: 321 GEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPS--ESRP 378
G PVP S G SGP P P PP P + S S PP + S P +S P
Sbjct: 148 GRFPVP-SPGHRSGP--------PEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSP 198
Query: 379 YHGMHGGGPGG-----PGGGPHSFPHPLPSLTGG--------HGGHPMQHNPNGPPPPWM 425
++ PGG PG P FP + GG P + P PP P
Sbjct: 199 HNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSR 258
Query: 426 ----QPPPPPMNQGPHPPGHHG--PPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMP 479
+PPPPP G P H PPP Q PV S P P
Sbjct: 259 ALDDKPPPPPPPVGNRPSIHREAVPPPPPQN-NKPPVPS-----------TPRPSASSQA 306
Query: 480 PPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASST-PLPWQQRSLP 531
PPPPPP +P PP PLPP + P P + S++SST PLP RS P
Sbjct: 307 PPPPPPPSRPGPP---PLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGP 356
Score = 73.9 bits (180), Expect = 3e-13
Identities = 66/216 (30%), Positives = 78/216 (36%), Gaps = 26/216 (12%)
Query: 327 ASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGG 386
A+ + SG + PL + A PPS P SGP E P
Sbjct: 115 ANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPE--PQRNRMPPP 172
Query: 387 PGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPP 446
G P S P P+PS P HN PP P P P P PG+ G
Sbjct: 173 RPDVGSKPDSIPPPVPSTPRPIQSSP--HNRGSPPVPGGPRQPSPGPTPPPFPGNRGTAL 230
Query: 447 MDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMM---PPPPPPPSGQ---------PPPPPS 494
+ +P+ S + +PP P + PPPPPPP G PPPPP
Sbjct: 231 GGGSIRQSPLSSS--SPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQ 288
Query: 495 GPLPPW------QQQQQQPPPPPPPSSSMASSTPLP 524
PP Q PPPPPPP S PLP
Sbjct: 289 NNKPPVPSTPRPSASSQAPPPPPPP--SRPGPPPLP 322
Score = 73.9 bits (180), Expect = 3e-13
Identities = 75/251 (29%), Positives = 88/251 (35%), Gaps = 66/251 (26%)
Query: 324 PVPASVGSTSGPATTPLASAPRP--AAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHG 381
P VGS P+ S PRP ++P N PP Q P GP+ P+ G
Sbjct: 171 PPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSP-----GPTPP-PFPG 224
Query: 382 MHGGGPGG--------PGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQ------- 426
G GG P S PLP + P PPPP
Sbjct: 225 NRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPS----RALDDKPPPPPPPVGNRPSIHRE 280
Query: 427 --PPPPPMNQGPH------------------PPGHHGPPPMDQYLGSTPVGSGVYRLHQ- 465
PPPPP N P PP GPPP+ S+ RL Q
Sbjct: 281 AVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPP---SSSGNDETPRLPQR 337
Query: 466 ----GKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASST 521
P P G P PPPPS +PPPP P + P PPPPP S S++
Sbjct: 338 NLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDP-----PGRSGPLPPPPPVSRNGSTS 392
Query: 522 PLPWQQRSLPA 532
R+LPA
Sbjct: 393 ------RALPA 397
Score = 40.8 bits (94), Expect = 0.003
Identities = 45/189 (23%), Positives = 61/189 (32%), Gaps = 31/189 (16%)
Query: 328 SVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGP 387
S+ S++ P +P S P P P+ PPPP R P SGP P +G
Sbjct: 340 SLSSSTPPLPSPGRSGPLPPPPSERPPPPV-------RDPPGRSGPLPPPPPVSRNGSTS 392
Query: 388 GGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPM 447
P LPS +G P P P PPPP G P
Sbjct: 393 RALPATPQ-----LPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGFQDSPCE 447
Query: 448 DQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPP---PPSGQPPPPPSGPLPPWQQQQ 504
D++ + H P+ +PPP P P ++
Sbjct: 448 DEW-------ESRFYFH---------PISDLPPPEPYVQTTKSYPSKLARNESRSGSNRR 491
Query: 505 QQPPPPPPP 513
++ PP PP
Sbjct: 492 ERGAPPLPP 500
Score = 39.3 bits (90), Expect = 0.009
Identities = 52/220 (23%), Positives = 66/220 (30%), Gaps = 56/220 (25%)
Query: 346 PAAPANNPPPPSLMSTTQSRPPWMN----------------------------SGPSESR 377
P P PPPP + + P +N S P +
Sbjct: 2 PVPPPPAPPPPPTFALANTEKPTLNKTEQAGRNALLSDISKGKKLKKTVTNDRSAPILDK 61
Query: 378 PYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPP--PWMQPPPPPMNQG 435
P GGG GG GGG GG GG GPP Q P +
Sbjct: 62 PKGAGAGGGGGGFGGGGGFGG-------GGGGGGGGSFGGGGPPGLGGLFQAGMPKLRST 114
Query: 436 PHPPGHHGP--PPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPP 493
+ G PP+ P G R K PP G P P P PP P
Sbjct: 115 ANRDNDSGGSRPPL------LPPGG---RSTSAKPFSPPSGPGRFPVPSPGHRSGPPEP- 164
Query: 494 SGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQRSLPAA 533
Q+ + PP P S + P+P R + ++
Sbjct: 165 -------QRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSS 197
>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
tract binding protein associated) [Homo sapiens]
Length = 707
Score = 83.2 bits (204), Expect = 6e-16
Identities = 61/176 (34%), Positives = 67/176 (38%), Gaps = 23/176 (13%)
Query: 381 GMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNP--NGPPPPWMQPPP--------- 429
G H G GG GG H F P P + PM P +GP PP PPP
Sbjct: 15 GFHRRGGGGGRGGLHDFRSPPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPP 74
Query: 430 ---PPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMP-----PPPMGMMPPP 481
PP PH P H P Q P S + QG G P PP PP
Sbjct: 75 QQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPA 134
Query: 482 PPPPSGQPPPPPSGPLP--PWQQQQQQP--PPPPPPSSSMASSTPLPWQQRSLPAA 533
PP SG PP GP P P P PPP PPSS + ++ P PAA
Sbjct: 135 TPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAA 190
Score = 67.8 bits (164), Expect = 2e-11
Identities = 60/192 (31%), Positives = 66/192 (34%), Gaps = 42/192 (21%)
Query: 355 PPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPH------PLPSLTGGH 408
PP M Q+R P M GP +S P P P PH P P H
Sbjct: 34 PPPGMGLNQNRGP-MGPGPGQSGPK-------PPIPPPPPHQQQQQPPPQQPPPQQPPPH 85
Query: 409 GG--HPMQHNPNGPPPPWMQPPPPPMNQGPHP--------PGHHGPPPMDQYLGSTPVGS 458
HP H PPPP P + QGP P P PP P GS
Sbjct: 86 QPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGS 145
Query: 459 GVYRLHQGKGMMPPP-----PMGMMPPPPP--------PPSGQPPPPPSGPLPPWQQQQQ 505
G G PPP P G PP PP P +G PPPPP+ P +Q
Sbjct: 146 G-----PGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQ 200
Query: 506 QPPPPPPPSSSM 517
P P P M
Sbjct: 201 GPGPGGPKGGKM 212
Score = 67.8 bits (164), Expect = 2e-11
Identities = 58/187 (31%), Positives = 68/187 (36%), Gaps = 30/187 (16%)
Query: 344 PRPAAPANNPPPPSLMST------------TQSRPPWMNSGPSESRPYHGMHGGGPGGPG 391
P+P PPPP S S PP +S P + P G PG
Sbjct: 91 PQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSG------APPG 144
Query: 392 GGPHSFPHPLPSLTGGHGGHPMQHNPNG-----PPPPWMQPPPPPMNQGPHPPGHHGPPP 446
GP P P P++T G P P+ PP PPPP GP P GP P
Sbjct: 145 SGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGP 204
Query: 447 MDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQ 506
G P G + G G+ P G P PP G+P PP+ QQ Q
Sbjct: 205 GGPKGGKMPGGP---KPGGGPGLSTP---GGHPKPPHRGGGEPRGGRQHH-PPYHQQHHQ 257
Query: 507 PPPPPPP 513
PPP P
Sbjct: 258 GPPPGGP 264
Score = 67.0 bits (162), Expect = 4e-11
Identities = 54/175 (30%), Positives = 61/175 (34%), Gaps = 34/175 (19%)
Query: 339 PLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFP 398
P+ P + P PPP Q PP P + P P
Sbjct: 46 PMGPGPGQSGPKPPIPPPPPHQQQQQPPP--QQPPPQQPP-------------------P 84
Query: 399 HPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHP-PG-HHGPPPMDQYLGSTPV 456
H P HP H PPPP P + QGP P PG PP +TP
Sbjct: 85 HQPPP-------HPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPP 137
Query: 457 GSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPP 511
SG G G P PP + PP P PP PPS +P Q PPPPP
Sbjct: 138 TSGA-PPGSGPGPTPTPPPAVTSAPPGAP---PPTPPSSGVPTTPPQAGGPPPPP 188
Score = 61.6 bits (148), Expect = 2e-09
Identities = 56/158 (35%), Positives = 66/158 (41%), Gaps = 31/158 (19%)
Query: 320 LGEAPVPASVGSTSGPATTPLASAPRPAAPANNP-PPPSLMSTTQSRPPWMNSGPSESRP 378
+G AP PAS S++ PAT P + AP + P P PPP++ S PP + PS P
Sbjct: 121 VGSAP-PAS--SSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPP--PTPPSSGVP 175
Query: 379 YHGMHGGGPG-------GPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPP---PWMQP- 427
GGP GPG GP P P GG G M P GP P P +
Sbjct: 176 TTPPQAGGPPPPPAAVPGPGPGPKQGPGP-----GGPKGGKM---PGGPKPGGGPGLSTP 227
Query: 428 ---PPPPMNQGPHPPG---HHGPPPMDQYLGSTPVGSG 459
P PP G P G HH P + G P G G
Sbjct: 228 GGHPKPPHRGGGEPRGGRQHHPPYHQQHHQGPPPGGPG 265
Score = 60.1 bits (144), Expect = 5e-09
Identities = 58/189 (30%), Positives = 64/189 (33%), Gaps = 30/189 (15%)
Query: 339 PLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFP 398
P P P P + PPP Q +PP P +S G GP G
Sbjct: 72 PPPQQPPPQQPPPHQPPPHPQPHQQQQPP---PPPQDSSKPVVAQGPGPAPGVGSAPPAS 128
Query: 399 HPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGS 458
P T G P P GP P PPP + P PG PPP TP S
Sbjct: 129 SSAPPATPPTSGAPPGSGP-GPTPT----PPPAVTSAP--PG--APPP-------TPPSS 172
Query: 459 GVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPP---PSS 515
GV PP G PPPP G P P GP P + + P P P P
Sbjct: 173 GV--------PTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGL 224
Query: 516 SMASSTPLP 524
S P P
Sbjct: 225 STPGGHPKP 233
Score = 52.0 bits (123), Expect = 1e-06
Identities = 41/102 (40%), Positives = 47/102 (46%), Gaps = 21/102 (20%)
Query: 453 STPVGSGVYRLHQGKGMMPPPPMGMMPPPP-PPP-----SGQPP---PPPSGPLP----- 498
S P G G L+Q +G M P P P PP PPP QPP PPP P P
Sbjct: 33 SPPPGMG---LNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPP 89
Query: 499 -PWQQQQQQPPPPPPPSSSMASST---PLPWQQRSLPAAAMA 536
P QQQQPPPPP SS + P P + PA++ A
Sbjct: 90 HPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSA 131
>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
sapiens]
Length = 505
Score = 82.0 bits (201), Expect = 1e-15
Identities = 50/121 (41%), Positives = 56/121 (46%), Gaps = 19/121 (15%)
Query: 412 PMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHG----PPPMDQYLGSTPVGSGVYRLHQGK 467
P + GPPPP PPPP N GP PP G PPP + + P R
Sbjct: 279 PPPPSRGGPPPP----PPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSR--PSV 332
Query: 468 GMMPPPPMGMMPPPPPP-----PSGQPPPPPS----GPLPPWQQQQQQPPPPPPPSSSMA 518
+ PPPP M PPPPP PSG PPPPPS GP+ P PPP PPP +
Sbjct: 333 AVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPPPPGPPPPPGLP 392
Query: 519 S 519
S
Sbjct: 393 S 393
Score = 70.5 bits (171), Expect = 4e-12
Identities = 52/135 (38%), Positives = 56/135 (41%), Gaps = 31/135 (22%)
Query: 385 GGPGGPGGGPH-SFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPP--PPMNQGPHPPGH 441
GGP P PH S P P P+ G P P PPP PPP P + P PP
Sbjct: 285 GGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPP---PPPSRPSVAVPPPPPNR 341
Query: 442 HGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPP--MGMMPPPPPPPSGQPPPPPSGPLPP 499
PPP S P G PPPP +G+ P PPPP PPPPP GP
Sbjct: 342 MYPPPPPALPSSAP-----------SGPPPPPPSVLGVGPVAPPPPP--PPPPPPGP--- 385
Query: 500 WQQQQQQPPPPPPPS 514
PPPP PS
Sbjct: 386 -------PPPPGLPS 393
Score = 69.3 bits (168), Expect = 8e-12
Identities = 71/223 (31%), Positives = 77/223 (34%), Gaps = 47/223 (21%)
Query: 288 IASDCKFQRPG----DPQSAQDKARMDKEYLSLMAELGEAPVPASVGSTS---------- 333
I + FQ G DP + D +D E +L G + TS
Sbjct: 203 IGTPSNFQHIGHVGWDPNTGFDLNNLDPELKNLFDMCGISEAQLKDRETSKVIYDFIEKT 262
Query: 334 GPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGG 393
G R A P PPPPS PP NSGP P G G P P
Sbjct: 263 GGVEAVKNELRRQAPP---PPPPSRGGPPPPPPPPHNSGPPPP-PARG-RGAPPPPPSRA 317
Query: 394 PHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGS 453
P + P P P P N PPPP P P GP PPP LG
Sbjct: 318 PTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAP--SGP-------PPPPPSVLGV 368
Query: 454 TPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGP 496
PV PPPP PPPPPPP PPPPP P
Sbjct: 369 GPVA-------------PPPP----PPPPPPPG--PPPPPGLP 392
Score = 68.2 bits (165), Expect = 2e-11
Identities = 43/112 (38%), Positives = 49/112 (43%), Gaps = 27/112 (24%)
Query: 420 PPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGM-- 477
PPPP PPPP P PP + GPPP +G+G PPPP
Sbjct: 279 PPPPSRGGPPPP----PPPPHNSGPPPPPA---------------RGRGAPPPPPSRAPT 319
Query: 478 MPPPPPPPS----GQPPPPPSG--PLPPWQQQQQQPPPPPPPSSSMASSTPL 523
PPPPPPS PPPPP+ P PP P PPPP S+ P+
Sbjct: 320 AAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPV 371
Score = 58.9 bits (141), Expect = 1e-08
Identities = 32/71 (45%), Positives = 36/71 (50%), Gaps = 6/71 (8%)
Query: 471 PPPPMGMMPPPPPP--PSGQPPPPPSG----PLPPWQQQQQQPPPPPPPSSSMASSTPLP 524
PPP G PPPPPP SG PPPP G P PP + PPPPPP S+A P P
Sbjct: 280 PPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPP 339
Query: 525 WQQRSLPAAAM 535
+ P A+
Sbjct: 340 NRMYPPPPPAL 350
Score = 53.5 bits (127), Expect = 5e-07
Identities = 25/51 (49%), Positives = 29/51 (56%), Gaps = 5/51 (9%)
Query: 479 PPPPPPPSGQPPPPP-----SGPLPPWQQQQQQPPPPPPPSSSMASSTPLP 524
PPPPPP G PPPPP SGP PP + + PPPPP + + A P P
Sbjct: 277 PPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPP 327
Score = 50.8 bits (120), Expect = 3e-06
Identities = 46/153 (30%), Positives = 54/153 (35%), Gaps = 30/153 (19%)
Query: 324 PVPASVGSTSGPATTPLASAPRP--AAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHG 381
P P S G P P S P P A PPPP + T + PP S PS + P
Sbjct: 279 PPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVP--- 335
Query: 382 MHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPP---------WMQPPPPPM 432
P +P P P+L P+GPPPP PPPPP
Sbjct: 336 --------PPPPNRMYPPPPPALPSSA--------PSGPPPPPPSVLGVGPVAPPPPPPP 379
Query: 433 NQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQ 465
P PP G P + T G+ L Q
Sbjct: 380 PPPPGPPPPPGLPSDGDHQVPTTAGNKAALLDQ 412
Score = 33.1 bits (74), Expect = 0.67
Identities = 18/50 (36%), Positives = 22/50 (44%), Gaps = 10/50 (20%)
Query: 489 PPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQRSLPAAAMARA 538
PPPPPS + PPPPPP + P P + R P +RA
Sbjct: 278 PPPPPS----------RGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRA 317
>gi|5730073 KH domain containing, RNA binding, signal transduction
associated 3 [Homo sapiens]
Length = 346
Score = 81.6 bits (200), Expect = 2e-15
Identities = 67/238 (28%), Positives = 106/238 (44%), Gaps = 45/238 (18%)
Query: 135 RVSDKVMIPQDEYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGKGSV----KEGKVGR 190
++ KV+IP ++P+ NFVG L+GPRGN+LK +++E K+ I GKGS+ KE ++ +
Sbjct: 55 KLGQKVLIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRK 114
Query: 191 KDGQMLPGEDEPLHALV-----TANTMENVKKAVEQIRNILKQGIETPEDQNDLRKMQLR 245
++ LH L+ A + A+E+I+ L P+ +++R+ QL+
Sbjct: 115 SGEAKYFHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFL-----IPDYNDEIRQAQLQ 169
Query: 246 ELARLNGTLREDDNRILRPWQSSETRSITNTTVCTKCGGAGHIASDCKFQRPGDPQSAQD 305
EL LNG D ++R + TR + + GG RP
Sbjct: 170 ELTYLNGGSENADVPVVRGKPTLRTRGVPAPAITRGRGGV--------TARP-------- 213
Query: 306 KARMDKEYLSLMAELGEAPVPASVGSTSGPAT------TPLASAPRPAAPANNPPPPS 357
+ ++ G P P V ST GP + TP A P PPPP+
Sbjct: 214 --------VGVVVPRG-TPTPRGVLSTRGPVSRGRGLLTPRARGVPPTGYRPPPPPPT 262
Score = 31.6 bits (70), Expect = 2.0
Identities = 16/40 (40%), Positives = 21/40 (52%), Gaps = 9/40 (22%)
Query: 454 TPVGSGVYR----LHQGKGMMPP-----PPMGMMPPPPPP 484
TP GV + +G+G++ P PP G PPPPPP
Sbjct: 222 TPTPRGVLSTRGPVSRGRGLLTPRARGVPPTGYRPPPPPP 261
>gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens]
Length = 1336
Score = 81.3 bits (199), Expect = 2e-15
Identities = 77/235 (32%), Positives = 91/235 (38%), Gaps = 34/235 (14%)
Query: 324 PVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRP-PWMNSGPSESRPYHGM 382
P P GP +S P+ PP P Q P P + GP GM
Sbjct: 681 PGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGM 740
Query: 383 HGG-GPGGPGGGPHSFPHPLPSLTGGHGGH-PMQHNP-NGPPPPWMQPPPPPM-NQGPHP 438
G GP G G PH PH + G G P+ P G P MQ PP P NQGP P
Sbjct: 741 QGPPGPRGMQGPPH--PHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPGPRENQGPAP 798
Query: 439 PGHHGPPPMDQYLGSTP----VGSGVYRLH---QGKGMMPPPPMGMMPPPPP-------- 483
G P + G P +G G + + +GM PPP G M PP
Sbjct: 799 QGMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGS 858
Query: 484 -----PPSGQPPPPPSGPL--PPWQQQQQQPPPPPPPSSSMASSTPLPWQQRSLP 531
PP G PPP G + PP Q QQ P P PS P+P+QQ+ P
Sbjct: 859 QSQQGPPQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQG-----PIPFQQQKTP 908
Score = 55.5 bits (132), Expect = 1e-07
Identities = 66/213 (30%), Positives = 72/213 (33%), Gaps = 32/213 (15%)
Query: 334 GPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGG----GPGG 389
GP PL P P RP M+ GP + + G HG GP G
Sbjct: 636 GPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMH-GPQGMQRHPGPHGPLGPQGPPG 694
Query: 390 PGGGPHSFPHPLPSLTGGHGGH--------PMQH-NPNGPP-PPWMQPPPPP--MNQGPH 437
P G H P G GH P H P GPP MQ PP P M PH
Sbjct: 695 PQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGMQGPPGPRGMQGPPH 754
Query: 438 PPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPM--GMMPPPPPPPSGQPPPPPSG 495
P G G P G PV G +GM PP P P G PP G
Sbjct: 755 PHGIQGGPGSQGIQG--PVSQGPLMGLNPRGMQGPPGPRENQGPAPQGMIMGHPPQEMRG 812
Query: 496 PLPP------WQQQQQQPP-----PPPPPSSSM 517
P PP Q+ + P PPP SM
Sbjct: 813 PHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSM 845
Score = 52.0 bits (123), Expect = 1e-06
Identities = 51/176 (28%), Positives = 62/176 (35%), Gaps = 27/176 (15%)
Query: 344 PRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPG-GGPHSFPHPLP 402
P+ PPP M PP GP S+ G G G P GG P P
Sbjct: 830 PQEIRGMQGPPPQGSMLG----PPQELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQG 885
Query: 403 SLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHH-----GPPPMDQYLGSTPVG 457
G HP Q P P+ Q P + GP P + GPPP+ LG
Sbjct: 886 QQNPARGPHPSQG-----PIPFQQQKTPLLGDGPRAPFNQEGQSTGPPPLIPGLGQ---- 936
Query: 458 SGVYRLHQG-KGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPP 512
QG +G +PP G P P S PP GP+ + +Q P P
Sbjct: 937 -------QGAQGRIPPLNPGQGPGPNKGDSRGPPNHHMGPMSERRHEQSGGPEHGP 985
Score = 51.6 bits (122), Expect = 2e-06
Identities = 67/208 (32%), Positives = 74/208 (35%), Gaps = 56/208 (26%)
Query: 324 PVPASVGSTSGPATTPLASAPRPAAPAN-NPPPPSL---MSTTQSRPPWMNSGPS-ESRP 378
P P+S GP P P P P PS M+ Q PP GP + RP
Sbjct: 574 PPPSSGTPLLGPQPFP-GQGPMSQIPQGFQQPHPSQQMPMNMAQMGPP----GPQGQFRP 628
Query: 379 YHGMHGGGPGGP-----GGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPP----P 429
GP GP GGGP F P P GPP +P P
Sbjct: 629 PGPQGQMGPQGPPLHQGGGGPQGFMGP--------------QGPQGPPQGLPRPQDMHGP 674
Query: 430 PPMNQ--GPHPP-GHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPS 486
M + GPH P G GPP P GS + H G PP P G + P
Sbjct: 675 QGMQRHPGPHGPLGPQGPP--------GPQGSSGPQGHMGP-QGPPGPQGHIGP------ 719
Query: 487 GQPPPPPSGPL----PPWQQQQQQPPPP 510
Q PP P G L PP Q Q PP P
Sbjct: 720 -QGPPGPQGHLGPQGPPGTQGMQGPPGP 746
Score = 48.9 bits (115), Expect = 1e-05
Identities = 44/135 (32%), Positives = 50/135 (37%), Gaps = 11/135 (8%)
Query: 388 GGPGGGPHSFPH--PLPSLTGG-HGGHPMQHNPN-----GPPPPWMQ--PPPPPMNQGPH 437
G P GP FP P+ + G HP Q P GPP P Q PP P GP
Sbjct: 579 GTPLLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQGQMGPQ 638
Query: 438 -PPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGP 496
PP H G ++G L + + M P M P P P Q PP P G
Sbjct: 639 GPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPGPQGS 698
Query: 497 LPPWQQQQQQPPPPP 511
P Q PP P
Sbjct: 699 SGPQGHMGPQGPPGP 713
Score = 35.8 bits (81), Expect = 0.10
Identities = 33/120 (27%), Positives = 42/120 (35%), Gaps = 6/120 (5%)
Query: 330 GSTSGPATTPLASAPRPAA---PANNP-PPPSLMSTTQSRPPWMNSGPSESRPYHGMHGG 385
GS P + P P PA P P + Q + P + GP G G
Sbjct: 867 GSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQSTG 926
Query: 386 GPGG-PGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGP 444
P PG G +P L G G P + + GPP M P ++ P HGP
Sbjct: 927 PPPLIPGLGQQGAQGRIPPLNPGQGPGPNKGDSRGPPNHHMGPMSERRHEQSGGP-EHGP 985
Score = 30.0 bits (66), Expect = 5.7
Identities = 18/46 (39%), Positives = 20/46 (43%), Gaps = 5/46 (10%)
Query: 482 PPPPSGQP-----PPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTP 522
PPP SG P P P GP+ Q QQP P +MA P
Sbjct: 574 PPPSSGTPLLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGP 619
Score = 30.0 bits (66), Expect = 5.7
Identities = 31/99 (31%), Positives = 38/99 (38%), Gaps = 13/99 (13%)
Query: 326 PASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGG 385
PAS +S +AS P P ++ P T++ R GPSE R G G
Sbjct: 1211 PASRERSSSLQGMDMASLPPRKRPWHDGP-----GTSEHREMEAPGGPSEDRGGKGRGGP 1265
Query: 386 GPGG--PGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPP 422
GP P G S SL G H + P G PP
Sbjct: 1266 GPAQRVPKSGRSS------SLDGEHHDGYHRDEPFGGPP 1298
>gi|189217895 KH domain-containing, RNA-binding, signal
transduction-associated protein 2 [Homo sapiens]
Length = 349
Score = 80.9 bits (198), Expect = 3e-15
Identities = 48/135 (35%), Positives = 78/135 (57%), Gaps = 16/135 (11%)
Query: 135 RVSDKVMIPQDEYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGKGSV----KEGKVGR 190
++S++V+IP +YP+ NFVG L+GPRGN+LK +++E AK+ I GKGS+ KE ++ +
Sbjct: 59 KLSERVLIPVKQYPKFNFVGKLLGPRGNSLKRLQEETGAKMSILGKGSMRDKAKEEELRK 118
Query: 191 KDGQMLPGEDEPLHALV-----TANTMENVKKAVEQIRNILKQGIETPEDQNDLRKMQLR 245
+ LH L+ + A+E+I+ L P+ +++R+ QLR
Sbjct: 119 SGEAKYAHLSDELHVLIEVFAPPGEAYSRMSHALEEIKKFL-----VPDYNDEIRQEQLR 173
Query: 246 ELARLNGTLREDDNR 260
EL+ LNG+ ED R
Sbjct: 174 ELSYLNGS--EDSGR 186
Score = 30.0 bits (66), Expect = 5.7
Identities = 24/74 (32%), Positives = 30/74 (40%), Gaps = 27/74 (36%)
Query: 427 PPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGM-MPPP---- 481
PPPPP +G TP GS V R G +P PP+ +P P
Sbjct: 211 PPPPPPGRGV----------------LTPRGSTVTR-----GALPVPPVARGVPTPRARG 249
Query: 482 -PPPPSGQPPPPPS 494
P P + PPPP+
Sbjct: 250 APTVPGYRAPPPPA 263
>gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens]
Length = 502
Score = 80.5 bits (197), Expect = 4e-15
Identities = 54/156 (34%), Positives = 62/156 (39%), Gaps = 51/156 (32%)
Query: 387 PGGPGGGPHSFPHPLPSLTGGHGGH--PMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGP 444
P P G + P P + GG+ G P+ PP P PPPP +GP PPG GP
Sbjct: 316 PPPPSRGGNQLPRP--PIVGGNKGRSGPL------PPVPLGIAPPPPTPRGPPPPGRGGP 367
Query: 445 PPMDQYLGSTPVGSGVYRLHQGKGMMPPPP----MGMMPPPPPPPSGQPPPPPSGPLPPW 500
PP PPPP G +PPPPP G P PPP
Sbjct: 368 PP------------------------PPPPATGRSGPLPPPPPGAGGPPMPPP------- 396
Query: 501 QQQQQQPPPPPPPSSSMASSTPLPWQQRSLPAAAMA 536
PPPPPPP SS P P +PA +A
Sbjct: 397 ------PPPPPPPPSSGNGPAPPPLPPALVPAGGLA 426
Score = 58.9 bits (141), Expect = 1e-08
Identities = 65/222 (29%), Positives = 78/222 (35%), Gaps = 37/222 (16%)
Query: 299 DPQSAQDKARMDKEYLSLMAELGEAPVPASVGSTSG---------PATTPLASAPRPAAP 349
DPQ+ D +D + SL + G + + TS + R P
Sbjct: 253 DPQNGFDVNNLDPDLRSLFSRAGISEAQLTDAETSKLIYDFIEDQGGLEAVRQEMRRQEP 312
Query: 350 ANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGG---------GPGGPG-GGPHSFPH 399
PPPPS RPP + S P + G GP PG GGP P
Sbjct: 313 LPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPPPPGRGGPPPPPP 372
Query: 400 P-------LPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLG 452
P LP G GG PM P PPP PPPP GP PP PP + G
Sbjct: 373 PATGRSGPLPPPPPGAGGPPMPPPP--PPP----PPPPSSGNGPAPPPL--PPALVPAGG 424
Query: 453 STPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPS 494
P G L Q + + P P + QPPP S
Sbjct: 425 LAPGGGRGALLDQ---IRQGIQLNKTPGAPESSALQPPPQSS 463
Score = 30.0 bits (66), Expect = 5.7
Identities = 15/35 (42%), Positives = 17/35 (48%), Gaps = 7/35 (20%)
Query: 470 MPPPPM-------GMMPPPPPPPSGQPPPPPSGPL 497
+PPPP G +PP P P G PP GPL
Sbjct: 159 LPPPPTPANEERRGGLPPLPLHPGGDQGGPPVGPL 193
>gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Homo
sapiens]
Length = 247
Score = 79.7 bits (195), Expect = 6e-15
Identities = 70/214 (32%), Positives = 78/214 (36%), Gaps = 43/214 (20%)
Query: 345 RPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSL 404
RP P P P QS+ P G E RP G G G PH P
Sbjct: 49 RPPPPPGKPQGPPPQGGNQSQGPPPPPGKPEGRPPQG----GNQSQGPPPHPGKPERPPP 104
Query: 405 TGGH---GGHPMQHNPNGPPPPW----MQPPPPP------------MNQGP--HPPGHHG 443
GG+ G P P PPP +PPPPP +QGP HP G
Sbjct: 105 QGGNQSQGTPPPPGKPERPPPQGGNQSHRPPPPPGKPERPPPQGGNQSQGPPPHPGKPEG 164
Query: 444 PPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQ 503
PPP + + R GK PP G P PPPP PPP+G P QQ
Sbjct: 165 PPPQEGNKSRSA------RSPPGKPQGPPQQEGNKPQGPPPPGKPQGPPPAGGNP---QQ 215
Query: 504 QQQPP------PPPPPSSSMASSTPLPWQQRSLP 531
Q PP PPPPP P P Q + P
Sbjct: 216 PQAPPAGKPQGPPPPP---QGGRPPRPAQGQQPP 246
Score = 69.7 bits (169), Expect = 6e-12
Identities = 49/126 (38%), Positives = 53/126 (42%), Gaps = 23/126 (18%)
Query: 410 GHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHH----GPPPMDQYLGSTPVGSGVYR--- 462
G P P G P PPPP QGP P G + PPP + G P G +
Sbjct: 34 GKPEGRRPQGGNQPQRPPPPPGKPQGPPPQGGNQSQGPPPPPGKPEGRPPQGGNQSQGPP 93
Query: 463 LHQGKGMMPPPPMGMM----PPPP-----PPPSG-----QPPPPPSGP--LPPWQQQQQQ 506
H GK PPP G PPPP PPP G +PPPPP P PP Q Q
Sbjct: 94 PHPGKPERPPPQGGNQSQGTPPPPGKPERPPPQGGNQSHRPPPPPGKPERPPPQGGNQSQ 153
Query: 507 PPPPPP 512
PPP P
Sbjct: 154 GPPPHP 159
Score = 68.2 bits (165), Expect = 2e-11
Identities = 60/203 (29%), Positives = 71/203 (34%), Gaps = 39/203 (19%)
Query: 322 EAPVPASVGSTSGPATTPLASAPRPAAPANNP------------PPPSLMSTTQSRPPWM 369
+ P P + GP P RP N PPP + +Q PP
Sbjct: 58 QGPPPQGGNQSQGPPPPPGKPEGRPPQGGNQSQGPPPHPGKPERPPPQGGNQSQGTPPPP 117
Query: 370 NSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPP------- 422
P P G P P G P P + + G HP + P GPPP
Sbjct: 118 GK-PERPPPQGGNQSHRPPPPPGKPERPPPQGGNQSQGPPPHPGK--PEGPPPQEGNKSR 174
Query: 423 ----PWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPP-PPMGM 477
P +P PP +G P GPPP + G P G G P PP G
Sbjct: 175 SARSPPGKPQGPPQQEGNKP---QGPPPPGKPQGPPPAG--------GNPQQPQAPPAGK 223
Query: 478 MPPPPPPPS-GQPPPPPSGPLPP 499
PPPPP G+PP P G PP
Sbjct: 224 PQGPPPPPQGGRPPRPAQGQQPP 246
Score = 62.0 bits (149), Expect = 1e-09
Identities = 55/167 (32%), Positives = 61/167 (36%), Gaps = 38/167 (22%)
Query: 373 PSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPM 432
P RP G P P G P P GG+ Q PPPP PP
Sbjct: 36 PEGRRPQGGNQPQRPPPPPGKPQGPPP--------QGGNQSQ---GPPPPPGKPEGRPPQ 84
Query: 433 --NQGPHPPGHHG----PPPM--DQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPP 484
NQ PP H G PPP +Q G+ P GK PPP G PPP
Sbjct: 85 GGNQSQGPPPHPGKPERPPPQGGNQSQGTPP--------PPGKPERPPPQGGNQSHRPPP 136
Query: 485 PSGQPPPPPSGPLPPWQQQQQQPPP-------PPPPSSSMASSTPLP 524
P G+P PP P Q Q PPP PPP + + S P
Sbjct: 137 PPGKPERPP----PQGGNQSQGPPPHPGKPEGPPPQEGNKSRSARSP 179
Score = 39.7 bits (91), Expect = 0.007
Identities = 27/68 (39%), Positives = 28/68 (41%), Gaps = 10/68 (14%)
Query: 463 LHQGKGMMPPPPMGMMPPPPPPPSGQPP-PPPSGPLPPWQQQQQQPPPP-----PPPSSS 516
L GK P G P PPPP G+P PPP G Q Q PPPP PP
Sbjct: 31 LISGKPEGRRPQGGNQPQRPPPPPGKPQGPPPQGG----NQSQGPPPPPGKPEGRPPQGG 86
Query: 517 MASSTPLP 524
S P P
Sbjct: 87 NQSQGPPP 94
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.134 0.421
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,990,543
Number of Sequences: 37866
Number of extensions: 3132291
Number of successful extensions: 81978
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1219
Number of HSP's successfully gapped in prelim test: 1698
Number of HSP's that attempted gapping in prelim test: 18813
Number of HSP's gapped (non-prelim): 24365
length of query: 548
length of database: 18,247,518
effective HSP length: 107
effective length of query: 441
effective length of database: 14,195,856
effective search space: 6260372496
effective search space used: 6260372496
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.