Guide to the Human Genome
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Search of human proteins with 42476325

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|42476325 solute carrier family 18 (vesicular monoamine),
member 2 [Homo sapiens]
         (514 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|42476325 solute carrier family 18 (vesicular monoamine), memb...  1014   0.0  
gi|208879454 solute carrier family 18 (vesicular monoamine), mem...   659   0.0  
gi|4506987 solute carrier family 18 (vesicular monoamine), membe...   659   0.0  
gi|215272390 solute carrier family 18 (vesicular monoamine), mem...   582   e-166
gi|215272392 solute carrier family 18 (vesicular monoamine), mem...   559   e-159
gi|118582257 vesicular acetylcholine transporter [Homo sapiens]       337   2e-92
gi|16445357 hypothetical protein LOC116843 [Homo sapiens]             100   2e-21
gi|22749525 major facilitator superfamily domain containing 8 [H...    45   1e-04
gi|6912666 sialin [Homo sapiens]                                       41   0.003
gi|42475555 monocarboxylate transporter 13 [Homo sapiens]              40   0.004
gi|34916028 solute carrier family 16 (monocarboxylic acid transp...    40   0.004
gi|148743791 solute carrier family 17 (sodium phosphate), member...    40   0.004
gi|213021148 SVOP-like isoform 1 [Homo sapiens]                        39   0.009
gi|23510410 solute carrier family 22 member 1 isoform b [Homo sa...    39   0.015
gi|4506999 solute carrier family 22 member 1 isoform a [Homo sap...    39   0.015
gi|157041233 solute carrier family 16 (monocarboxylic acid trans...    38   0.019
gi|225703102 major facilitator superfamily domain containing 10 ...    37   0.043
gi|225703104 major facilitator superfamily domain containing 10 ...    37   0.043
gi|4507001 solute carrier family 22 member 2 [Homo sapiens]            37   0.056
gi|5730045 solute carrier family 16, member 2 [Homo sapiens]           37   0.056
gi|24431958 solute carrier family 16, member 7 [Homo sapiens]          36   0.096
gi|21553331 solute carrier family 2 (facilitated glucose transpo...    36   0.096
gi|109288010 solute carrier family 16, member 3 [Homo sapiens]         35   0.13 
gi|109288012 solute carrier family 16, member 3 [Homo sapiens]         35   0.13 
gi|4759112 solute carrier family 16, member 3 [Homo sapiens]           35   0.13 
gi|41327156 solute carrier family 16 (monocarboxylic acid transp...    35   0.13 
gi|24497480 solute carrier family 22 member 6 isoform d [Homo sa...    35   0.21 
gi|24497478 solute carrier family 22 member 6 isoform c [Homo sa...    35   0.21 
gi|24497476 solute carrier family 22 member 6 isoform b [Homo sa...    35   0.21 
gi|20070188 solute carrier family 22 member 6 isoform a [Homo sa...    35   0.21 

>gi|42476325 solute carrier family 18 (vesicular monoamine), member
           2 [Homo sapiens]
          Length = 514

 Score = 1014 bits (2622), Expect = 0.0
 Identities = 514/514 (100%), Positives = 514/514 (100%)

Query: 1   MALSELALVRWLQESRRSRKLILFIVFLALLLDNMLLTVVVPIIPSYLYSIKHEKNATEI 60
           MALSELALVRWLQESRRSRKLILFIVFLALLLDNMLLTVVVPIIPSYLYSIKHEKNATEI
Sbjct: 1   MALSELALVRWLQESRRSRKLILFIVFLALLLDNMLLTVVVPIIPSYLYSIKHEKNATEI 60

Query: 61  QTARPVHTASISDSFQSIFSYYDNSTMVTGNATRDLTLHQTATQHMVTNASAVPSDCPSE 120
           QTARPVHTASISDSFQSIFSYYDNSTMVTGNATRDLTLHQTATQHMVTNASAVPSDCPSE
Sbjct: 61  QTARPVHTASISDSFQSIFSYYDNSTMVTGNATRDLTLHQTATQHMVTNASAVPSDCPSE 120

Query: 121 DKDLLNENVQVGLLFASKATVQLITNPFIGLLTNRIGYPIPIFAGFCIMFVSTIMFAFSS 180
           DKDLLNENVQVGLLFASKATVQLITNPFIGLLTNRIGYPIPIFAGFCIMFVSTIMFAFSS
Sbjct: 121 DKDLLNENVQVGLLFASKATVQLITNPFIGLLTNRIGYPIPIFAGFCIMFVSTIMFAFSS 180

Query: 181 SYAFLLIARSLQGIGSSCSSVAGMGMLASVYTDDEERGNVMGIALGGLAMGVLVGPPFGS 240
           SYAFLLIARSLQGIGSSCSSVAGMGMLASVYTDDEERGNVMGIALGGLAMGVLVGPPFGS
Sbjct: 181 SYAFLLIARSLQGIGSSCSSVAGMGMLASVYTDDEERGNVMGIALGGLAMGVLVGPPFGS 240

Query: 241 VLYEFVGKTAPFLVLAALVLLDGAIQLFVLQPSRVQPESQKGTPLTTLLKDPYILIAAGS 300
           VLYEFVGKTAPFLVLAALVLLDGAIQLFVLQPSRVQPESQKGTPLTTLLKDPYILIAAGS
Sbjct: 241 VLYEFVGKTAPFLVLAALVLLDGAIQLFVLQPSRVQPESQKGTPLTTLLKDPYILIAAGS 300

Query: 301 ICFANMGIAMLEPALPIWMMETMCSRKWQLGVAFLPASISYLIGTNIFGILAHKMGRWLC 360
           ICFANMGIAMLEPALPIWMMETMCSRKWQLGVAFLPASISYLIGTNIFGILAHKMGRWLC
Sbjct: 301 ICFANMGIAMLEPALPIWMMETMCSRKWQLGVAFLPASISYLIGTNIFGILAHKMGRWLC 360

Query: 361 ALLGMIIVGVSILCIPFAKNIYGLIAPNFGVGFAIGMVDSSMMPIMGYLVDLRHVSVYGS 420
           ALLGMIIVGVSILCIPFAKNIYGLIAPNFGVGFAIGMVDSSMMPIMGYLVDLRHVSVYGS
Sbjct: 361 ALLGMIIVGVSILCIPFAKNIYGLIAPNFGVGFAIGMVDSSMMPIMGYLVDLRHVSVYGS 420

Query: 421 VYAIADVAFCMGYAIGPSAGGAIAKAIGFPWLMTIIGIIDILFAPLCFFLRSPPAKEEKM 480
           VYAIADVAFCMGYAIGPSAGGAIAKAIGFPWLMTIIGIIDILFAPLCFFLRSPPAKEEKM
Sbjct: 421 VYAIADVAFCMGYAIGPSAGGAIAKAIGFPWLMTIIGIIDILFAPLCFFLRSPPAKEEKM 480

Query: 481 AILMDHNCPIKTKMYTQNNIQSYPIGEDEESESD 514
           AILMDHNCPIKTKMYTQNNIQSYPIGEDEESESD
Sbjct: 481 AILMDHNCPIKTKMYTQNNIQSYPIGEDEESESD 514


>gi|208879454 solute carrier family 18 (vesicular monoamine), member
           1 isoform a [Homo sapiens]
          Length = 525

 Score =  659 bits (1700), Expect = 0.0
 Identities = 331/513 (64%), Positives = 408/513 (79%), Gaps = 9/513 (1%)

Query: 10  RWLQESRRSRKLILFIVFLALLLDNMLLTVVVPIIPSYLYSI--KHEKNATEIQTARPVH 67
           R L+E R SR+L+L +VF+ALLLDNML TVVVPI+P++LY +  K   ++  +  A    
Sbjct: 11  RLLKEGRASRQLVLVVVFVALLLDNMLFTVVVPIVPTFLYDMEFKEVNSSLHLGHAGSSP 70

Query: 68  TASISDSFQSIFSYYDNSTMVTGNATRDLTLHQTATQHMV----TNA-SAVPSDCPSEDK 122
            A  S +F +IFS+++N+T+    +          T   +    T A SA  ++C     
Sbjct: 71  HALASPAFSTIFSFFNNNTVAVEESVPSGIAWMNDTASTIPPPATEAISAHKNNCLQGTG 130

Query: 123 DLLNENVQVGLLFASKATVQLITNPFIGLLTNRIGYPIPIFAGFCIMFVSTIMFAFSSSY 182
            L  E  +VG+LFASKA +QL+ NPF+G LTNRIGY IP+FAGF IMF+ST+MFAFS +Y
Sbjct: 131 FLEEEITRVGVLFASKAVMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLSTVMFAFSGTY 190

Query: 183 AFLLIARSLQGIGSSCSSVAGMGMLASVYTDDEERGNVMGIALGGLAMGVLVGPPFGSVL 242
             L +AR+LQGIGSS SSVAG+GMLASVYTDD ERG  MG ALGGLA+G+LVG PFGSV+
Sbjct: 191 TLLFVARTLQGIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGLLVGAPFGSVM 250

Query: 243 YEFVGKTAPFLVLAALVLLDGAIQLFVLQPSRVQPESQKGTPLTTLLKDPYILIAAGSIC 302
           YEFVGK+APFL+LA L LLDGA+QL +LQPS+V PES KGTPL  LLKDPYIL+AAGSIC
Sbjct: 251 YEFVGKSAPFLILAFLALLDGALQLCILQPSKVSPESAKGTPLFMLLKDPYILVAAGSIC 310

Query: 303 FANMGIAMLEPALPIWMMETMCSRKWQLGVAFLPASISYLIGTNIFGILAHKMGRWLCAL 362
           FANMG+A+LEP LPIWMM+TMCS KWQLG+AFLPAS+SYLIGTN+FG+LA+KMGRWLC+L
Sbjct: 311 FANMGVAILEPTLPIWMMQTMCSPKWQLGLAFLPASVSYLIGTNLFGVLANKMGRWLCSL 370

Query: 363 LGMIIVGVSILCIPFAKNIYGLIAPNFGVGFAIGMVDSSMMPIMGYLVDLRHVSVYGSVY 422
           +GM++VG S+LC+P A NI+GLI PN G+G AIGMVDSSMMPIMG+LVDLRH SVYGSVY
Sbjct: 371 IGMLVVGTSLLCVPLAHNIFGLIGPNAGLGLAIGMVDSSMMPIMGHLVDLRHTSVYGSVY 430

Query: 423 AIADVAFCMGYAIGPSAGGAIAKAIGFPWLMTIIGIIDILFAPLCFFLRSPPAKEEKMAI 482
           AIADVAFCMG+AIGPS GGAI KAIGFPWLM I G+I+I++APLC++LRSPPAKEEK+AI
Sbjct: 431 AIADVAFCMGFAIGPSTGGAIVKAIGFPWLMVITGVINIVYAPLCYYLRSPPAKEEKLAI 490

Query: 483 LMDHNCPIKTKMY-TQNNIQSYPIGEDEESESD 514
           L   +CP++T+MY TQ   + +P+GED + E D
Sbjct: 491 L-SQDCPMETRMYATQKPTKEFPLGEDSDEEPD 522


>gi|4506987 solute carrier family 18 (vesicular monoamine), member 1
           isoform a [Homo sapiens]
          Length = 525

 Score =  659 bits (1700), Expect = 0.0
 Identities = 331/513 (64%), Positives = 408/513 (79%), Gaps = 9/513 (1%)

Query: 10  RWLQESRRSRKLILFIVFLALLLDNMLLTVVVPIIPSYLYSI--KHEKNATEIQTARPVH 67
           R L+E R SR+L+L +VF+ALLLDNML TVVVPI+P++LY +  K   ++  +  A    
Sbjct: 11  RLLKEGRASRQLVLVVVFVALLLDNMLFTVVVPIVPTFLYDMEFKEVNSSLHLGHAGSSP 70

Query: 68  TASISDSFQSIFSYYDNSTMVTGNATRDLTLHQTATQHMV----TNA-SAVPSDCPSEDK 122
            A  S +F +IFS+++N+T+    +          T   +    T A SA  ++C     
Sbjct: 71  HALASPAFSTIFSFFNNNTVAVEESVPSGIAWMNDTASTIPPPATEAISAHKNNCLQGTG 130

Query: 123 DLLNENVQVGLLFASKATVQLITNPFIGLLTNRIGYPIPIFAGFCIMFVSTIMFAFSSSY 182
            L  E  +VG+LFASKA +QL+ NPF+G LTNRIGY IP+FAGF IMF+ST+MFAFS +Y
Sbjct: 131 FLEEEITRVGVLFASKAVMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLSTVMFAFSGTY 190

Query: 183 AFLLIARSLQGIGSSCSSVAGMGMLASVYTDDEERGNVMGIALGGLAMGVLVGPPFGSVL 242
             L +AR+LQGIGSS SSVAG+GMLASVYTDD ERG  MG ALGGLA+G+LVG PFGSV+
Sbjct: 191 TLLFVARTLQGIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGLLVGAPFGSVM 250

Query: 243 YEFVGKTAPFLVLAALVLLDGAIQLFVLQPSRVQPESQKGTPLTTLLKDPYILIAAGSIC 302
           YEFVGK+APFL+LA L LLDGA+QL +LQPS+V PES KGTPL  LLKDPYIL+AAGSIC
Sbjct: 251 YEFVGKSAPFLILAFLALLDGALQLCILQPSKVSPESAKGTPLFMLLKDPYILVAAGSIC 310

Query: 303 FANMGIAMLEPALPIWMMETMCSRKWQLGVAFLPASISYLIGTNIFGILAHKMGRWLCAL 362
           FANMG+A+LEP LPIWMM+TMCS KWQLG+AFLPAS+SYLIGTN+FG+LA+KMGRWLC+L
Sbjct: 311 FANMGVAILEPTLPIWMMQTMCSPKWQLGLAFLPASVSYLIGTNLFGVLANKMGRWLCSL 370

Query: 363 LGMIIVGVSILCIPFAKNIYGLIAPNFGVGFAIGMVDSSMMPIMGYLVDLRHVSVYGSVY 422
           +GM++VG S+LC+P A NI+GLI PN G+G AIGMVDSSMMPIMG+LVDLRH SVYGSVY
Sbjct: 371 IGMLVVGTSLLCVPLAHNIFGLIGPNAGLGLAIGMVDSSMMPIMGHLVDLRHTSVYGSVY 430

Query: 423 AIADVAFCMGYAIGPSAGGAIAKAIGFPWLMTIIGIIDILFAPLCFFLRSPPAKEEKMAI 482
           AIADVAFCMG+AIGPS GGAI KAIGFPWLM I G+I+I++APLC++LRSPPAKEEK+AI
Sbjct: 431 AIADVAFCMGFAIGPSTGGAIVKAIGFPWLMVITGVINIVYAPLCYYLRSPPAKEEKLAI 490

Query: 483 LMDHNCPIKTKMY-TQNNIQSYPIGEDEESESD 514
           L   +CP++T+MY TQ   + +P+GED + E D
Sbjct: 491 L-SQDCPMETRMYATQKPTKEFPLGEDSDEEPD 522


>gi|215272390 solute carrier family 18 (vesicular monoamine), member
           1 isoform b [Homo sapiens]
          Length = 493

 Score =  582 bits (1499), Expect = e-166
 Identities = 304/513 (59%), Positives = 378/513 (73%), Gaps = 41/513 (7%)

Query: 10  RWLQESRRSRKLILFIVFLALLLDNMLLTVVVPIIPSYLYSI--KHEKNATEIQTARPVH 67
           R L+E R SR+L+L +VF+ALLLDNML TVVVPI+P++LY +  K   ++  +  A    
Sbjct: 11  RLLKEGRASRQLVLVVVFVALLLDNMLFTVVVPIVPTFLYDMEFKEVNSSLHLGHAGSSP 70

Query: 68  TASISDSFQSIFSYYDNSTMVTGNATRDLTLHQTATQHMV----TNA-SAVPSDCPSEDK 122
            A  S +F +IFS+++N+T+    +          T   +    T A SA  ++C     
Sbjct: 71  HALASPAFSTIFSFFNNNTVAVEESVPSGIAWMNDTASTIPPPATEAISAHKNNCLQGTG 130

Query: 123 DLLNENVQVGLLFASKATVQLITNPFIGLLTNRIGYPIPIFAGFCIMFVSTIMFAFSSSY 182
            L  E  +VG+LFASKA +QL+ NPF+G LTNRIGY IP+FAGF IMF+ST+MFAFS +Y
Sbjct: 131 FLEEEITRVGVLFASKAVMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLSTVMFAFSGTY 190

Query: 183 AFLLIARSLQGIGSSCSSVAGMGMLASVYTDDEERGNVMGIALGGLAMGVLVGPPFGSVL 242
             L +AR+LQGIGSS SSVAG+GMLASVYTDD ERG  MG ALGGLA+G+LVG PFGSV+
Sbjct: 191 TLLFVARTLQGIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGLLVGAPFGSVM 250

Query: 243 YEFVGKTAPFLVLAALVLLDGAIQLFVLQPSRVQPESQKGTPLTTLLKDPYILIAAGSIC 302
           YEFVGK+APFL+LA L LLDGA+QL +LQPS+V PES KGTPL  LLKDPYIL+AA    
Sbjct: 251 YEFVGKSAPFLILAFLALLDGALQLCILQPSKVSPESAKGTPLFMLLKDPYILVAA---- 306

Query: 303 FANMGIAMLEPALPIWMMETMCSRKWQLGVAFLPASISYLIGTNIFGILAHKMGRWLCAL 362
                                       G+AFLPAS+SYLIGTN+FG+LA+KMGRWLC+L
Sbjct: 307 ----------------------------GLAFLPASVSYLIGTNLFGVLANKMGRWLCSL 338

Query: 363 LGMIIVGVSILCIPFAKNIYGLIAPNFGVGFAIGMVDSSMMPIMGYLVDLRHVSVYGSVY 422
           +GM++VG S+LC+P A NI+GLI PN G+G AIGMVDSSMMPIMG+LVDLRH SVYGSVY
Sbjct: 339 IGMLVVGTSLLCVPLAHNIFGLIGPNAGLGLAIGMVDSSMMPIMGHLVDLRHTSVYGSVY 398

Query: 423 AIADVAFCMGYAIGPSAGGAIAKAIGFPWLMTIIGIIDILFAPLCFFLRSPPAKEEKMAI 482
           AIADVAFCMG+AIGPS GGAI KAIGFPWLM I G+I+I++APLC++LRSPPAKEEK+AI
Sbjct: 399 AIADVAFCMGFAIGPSTGGAIVKAIGFPWLMVITGVINIVYAPLCYYLRSPPAKEEKLAI 458

Query: 483 LMDHNCPIKTKMY-TQNNIQSYPIGEDEESESD 514
           L   +CP++T+MY TQ   + +P+GED + E D
Sbjct: 459 L-SQDCPMETRMYATQKPTKEFPLGEDSDEEPD 490


>gi|215272392 solute carrier family 18 (vesicular monoamine), member
           1 isoform c [Homo sapiens]
          Length = 472

 Score =  559 bits (1440), Expect = e-159
 Identities = 284/439 (64%), Positives = 346/439 (78%), Gaps = 7/439 (1%)

Query: 10  RWLQESRRSRKLILFIVFLALLLDNMLLTVVVPIIPSYLYSI--KHEKNATEIQTARPVH 67
           R L+E R SR+L+L +VF+ALLLDNML TVVVPI+P++LY +  K   ++  +  A    
Sbjct: 11  RLLKEGRASRQLVLVVVFVALLLDNMLFTVVVPIVPTFLYDMEFKEVNSSLHLGHAGSSP 70

Query: 68  TASISDSFQSIFSYYDNSTMVTGNATRDLTLHQTATQHMV----TNA-SAVPSDCPSEDK 122
            A  S +F +IFS+++N+T+    +          T   +    T A SA  ++C     
Sbjct: 71  HALASPAFSTIFSFFNNNTVAVEESVPSGIAWMNDTASTIPPPATEAISAHKNNCLQGTG 130

Query: 123 DLLNENVQVGLLFASKATVQLITNPFIGLLTNRIGYPIPIFAGFCIMFVSTIMFAFSSSY 182
            L  E  +VG+LFASKA +QL+ NPF+G LTNRIGY IP+FAGF IMF+ST+MFAFS +Y
Sbjct: 131 FLEEEITRVGVLFASKAVMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLSTVMFAFSGTY 190

Query: 183 AFLLIARSLQGIGSSCSSVAGMGMLASVYTDDEERGNVMGIALGGLAMGVLVGPPFGSVL 242
             L +AR+LQGIGSS SSVAG+GMLASVYTDD ERG  MG ALGGLA+G+LVG PFGSV+
Sbjct: 191 TLLFVARTLQGIGSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGLLVGAPFGSVM 250

Query: 243 YEFVGKTAPFLVLAALVLLDGAIQLFVLQPSRVQPESQKGTPLTTLLKDPYILIAAGSIC 302
           YEFVGK+APFL+LA L LLDGA+QL +LQPS+V PES KGTPL  LLKDPYIL+AAGSIC
Sbjct: 251 YEFVGKSAPFLILAFLALLDGALQLCILQPSKVSPESAKGTPLFMLLKDPYILVAAGSIC 310

Query: 303 FANMGIAMLEPALPIWMMETMCSRKWQLGVAFLPASISYLIGTNIFGILAHKMGRWLCAL 362
           FANMG+A+LEP LPIWMM+TMCS KWQLG+AFLPAS+SYLIGTN+FG+LA+KMGRWLC+L
Sbjct: 311 FANMGVAILEPTLPIWMMQTMCSPKWQLGLAFLPASVSYLIGTNLFGVLANKMGRWLCSL 370

Query: 363 LGMIIVGVSILCIPFAKNIYGLIAPNFGVGFAIGMVDSSMMPIMGYLVDLRHVSVYGSVY 422
           +GM++VG S+LC+P A NI+GLI PN G+G AIGMVDSSMMPIMG+LVDLRH SVYGSVY
Sbjct: 371 IGMLVVGTSLLCVPLAHNIFGLIGPNAGLGLAIGMVDSSMMPIMGHLVDLRHTSVYGSVY 430

Query: 423 AIADVAFCMGYAIGPSAGG 441
           AIADVAFCMG+AIG S  G
Sbjct: 431 AIADVAFCMGFAIGYSESG 449


>gi|118582257 vesicular acetylcholine transporter [Homo sapiens]
          Length = 532

 Score =  337 bits (863), Expect = 2e-92
 Identities = 183/467 (39%), Positives = 281/467 (60%), Gaps = 26/467 (5%)

Query: 12  LQESRRSRKLILFIVFLALLLDNMLLTVVVPIIPSYLYSIKHEKNATEIQTARPVHTASI 71
           LQE RR R+L+L IV +ALLLDNML  V+VPI+P Y   I H +   E     P  T  +
Sbjct: 25  LQEPRRQRRLVLVIVCVALLLDNMLYMVIVPIVPDY---IAHMRGGGE----GPTRTPEV 77

Query: 72  SDSFQSIFSYYDNSTMVTGNATRDLTLHQTATQHMVTNASAVPSDCPSEDKDLLNENVQV 131
            +    + +   N++  T N +   T    A        SA+    P+E +D     V++
Sbjct: 78  WEPTLPLPTPA-NASAYTANTSASPTAAWPA-------GSALRPRYPTESED-----VKI 124

Query: 132 GLLFASKATVQLITNPFIGLLTNRIGYPIPIFAGFCIMFVSTIMFAFSSSYAFLLIARSL 191
           G+LFASKA +QL+ NP  G   +R+ Y +P+  G  +MF ST++FAF+  YA L  ARSL
Sbjct: 125 GVLFASKAILQLLVNPLSGPFIDRMSYDVPLLIGLGVMFASTVLFAFAEDYATLFAARSL 184

Query: 192 QGIGSSCSSVAGMGMLASVYTDDEERGNVMGIALGGLAMGVLVGPPFGSVLYEFVGKTAP 251
           QG+GS+ +  +G+ M+A  Y ++ ER   +G+AL  ++ G LV PPFG +LYEF GK  P
Sbjct: 185 QGLGSAFADTSGIAMIADKYPEEPERSRALGVALAFISFGSLVAPPFGGILYEFAGKRVP 244

Query: 252 FLVLAALVLLDGAIQLFVLQP----SRVQPESQKGTPLTTLLKDPYILIAAGSICFANMG 307
           FLVLAA+ L D  + L V +P    +R +     GTP+  L+ DPYI + AG++   N+ 
Sbjct: 245 FLVLAAVSLFDALLLLAVAKPFSAAARARANLPVGTPIHRLMLDPYIAVVAGALTTCNIP 304

Query: 308 IAMLEPALPIWMMETMCSRKWQLGVAFLPASISYLIGTNIFGILAHKMG--RWLCALLGM 365
           +A LEP +  WM  TM + +W++G+A+LPA + +++G  +   LA +    +WL   LG+
Sbjct: 305 LAFLEPTIATWMKHTMAASEWEMGMAWLPAFVPHVLGVYLTVRLAARYPHLQWLYGALGL 364

Query: 366 IIVGVSILCIPFAKNIYGLIAPNFGVGFAIGMVDSSMMPIMGYLVDLRHVSVYGSVYAIA 425
            ++G S   +P  ++   L+    G+ F I +VD++++P + +LVD+RHVSVYGSVYAIA
Sbjct: 365 AVIGASSCIVPACRSFAPLVVSLCGLCFGIALVDTALLPTLAFLVDVRHVSVYGSVYAIA 424

Query: 426 DVAFCMGYAIGPSAGGAIAKAIGFPWLMTIIGIIDILFAPLCFFLRS 472
           D+++ + YA+GP   G I  ++GF  L   +G+ ++L+AP+   LR+
Sbjct: 425 DISYSVAYALGPIVAGHIVHSLGFEQLSLGMGLANLLYAPVLLLLRN 471


>gi|16445357 hypothetical protein LOC116843 [Homo sapiens]
          Length = 456

 Score =  100 bits (250), Expect = 2e-21
 Identities = 87/365 (23%), Positives = 152/365 (41%), Gaps = 34/365 (9%)

Query: 118 PSEDKDLLNENVQVGLLFASKATVQLITNPFIGLLTNRIGYPIPIFAGFCIMFVSTIMFA 177
           P E +     N  +G++F   A  +L+ +   G     IG      AG  +    TI+F 
Sbjct: 59  PKEAEKKGASNTIIGMIFGCFALFELLASLVFGNYLVHIGAKFMFVAGMFVSGGVTILFG 118

Query: 178 FSSSY-------AFLLIARSLQGIGSSCSSVAGMGMLASVYTDDEERGNVMGIALGGLAM 230
                       A   + R +  +  + +  A   +LA  + ++     V+G       +
Sbjct: 119 VLDRVPDGPVFIAMCFLVRVMDAVSFAAAMTASSSILAKAFPNNV--ATVLGSLETFSGL 176

Query: 231 GVLVGPPFGSVLYEFVGKTAPFLVLAALVLLDGAIQLFVLQPSRVQPESQKGTPLTTLLK 290
           G+++GPP G  LY+  G   PF+VL  +VLL   + +++L      P       L  L K
Sbjct: 177 GLILGPPVGGFLYQSFGYEVPFIVLGCVVLLMVPLNMYILPNYESDPGEHSFWKLIALPK 236

Query: 291 DPYILIAAGSI--CFANMGIAMLEPALPIWMMETMCSRKWQLGVAFLPASISYLIGTNIF 348
              I     S+  CF       L+P L ++++E        +G+ FL  ++SY I + +F
Sbjct: 237 VGLIAFVINSLSSCF-----GFLDPTLSLFVLEKFNLPAGYVGLVFLGMALSYAISSPLF 291

Query: 349 GILAHK---MGRWLCALLGMIIVGVSILCIP-----FAKNIYGLIAPNFGVGFAIGMVDS 400
           G+L+ K   + +WL     +I  G  +L  P         ++ L+      G + GM   
Sbjct: 292 GLLSDKRPPLRKWLLVFGNLITAGCYMLLGPVPILHIKSQLWLLVLILVVSGLSAGM--- 348

Query: 401 SMMPIMGYLVDLRH-------VSVYGSVYAIADVAFCMGYAIGPSAGGAIAKAIGFPWLM 453
           S++P    ++   H       +S  G V  +    + +G  +GP+ GG + + IGF W  
Sbjct: 349 SIIPTFPEILSCAHENGFEEGLSTLGLVSGLFSAMWSIGAFMGPTLGGFLYEKIGFEWAA 408

Query: 454 TIIGI 458
            I G+
Sbjct: 409 AIQGL 413



 Score = 33.1 bits (74), Expect = 0.62
 Identities = 47/210 (22%), Positives = 88/210 (41%), Gaps = 18/210 (8%)

Query: 272 PSRVQPESQKG-TPLTTLLKDPYILIAAGSICFANMGI-AMLEPALPIWMMETMCSRKWQ 329
           P    P    G TP     +  ++LI+A S+   +M   ++L P  P    E   +    
Sbjct: 13  PGGDDPAGSAGETPGWLSREQVFVLISAASVNLGSMMCYSILGPFFPK-EAEKKGASNTI 71

Query: 330 LGVAFLPASISYLIGTNIFGILAHKMGRWLCALLGMIIVG-VSILCIPFAKNIYG----- 383
           +G+ F   ++  L+ + +FG     +G     + GM + G V+IL     +   G     
Sbjct: 72  IGMIFGCFALFELLASLVFGNYLVHIGAKFMFVAGMFVSGGVTILFGVLDRVPDGPVFIA 131

Query: 384 ---LIAPNFGVGFAIGMVDSSMMPIMGYLVDLRHVSVYGSVYAIADVAFCMGYAIGPSAG 440
              L+     V FA  M  SS +    +  ++   +V GS+   +     +G  +GP  G
Sbjct: 132 MCFLVRVMDAVSFAAAMTASSSILAKAFPNNV--ATVLGSLETFSG----LGLILGPPVG 185

Query: 441 GAIAKAIGFPWLMTIIGIIDILFAPLCFFL 470
           G + ++ G+     ++G + +L  PL  ++
Sbjct: 186 GFLYQSFGYEVPFIVLGCVVLLMVPLNMYI 215


>gi|22749525 major facilitator superfamily domain containing 8 [Homo
           sapiens]
          Length = 518

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 42/171 (24%), Positives = 78/171 (45%), Gaps = 23/171 (13%)

Query: 131 VGLLFASKATVQLITNPFIGLLTNRIGYPIPIFAGFCIMFVSTIMFAF-----SSSYAFL 185
           +G + AS +  Q++ +P  GL +N      P+     I   +  ++A+     S +  ++
Sbjct: 76  LGWVIASYSLGQMVASPIFGLWSNYRPRKEPLIVSILISVAANCLYAYLHIPASHNKYYM 135

Query: 186 LIARSLQGIGSSCSSVAGMGMLASVYTDDEERGNVMGIALGGLAMGVLVGPPFGSVLYEF 245
           L+AR L GIG+   +VA +    +  T  +ER + M       A+G ++GP F    + F
Sbjct: 136 LVARGLLGIGA--GNVAVVRSYTAGATSLQERTSSMANISMCQALGFILGPVF-QTCFTF 192

Query: 246 VGK---------------TAPFLVLAALVLLDGAIQLFVLQPSRVQPESQK 281
           +G+               T P L+ A L +L+  + L +L+  RV    ++
Sbjct: 193 LGEKGVTWDVIKLQINMYTTPVLLSAFLGILNIILILAILREHRVDDSGRQ 243


>gi|6912666 sialin [Homo sapiens]
          Length = 495

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 60/267 (22%), Positives = 101/267 (37%), Gaps = 47/267 (17%)

Query: 150 GLLTNRIGYPIPIFAGFCIMFVSTIMFAFSSSYAF--LLIARSLQGIGSSCSSVAGMGML 207
           G + ++IG  + +  G     V T+    ++      L++ R+L+G+G   +  A   M 
Sbjct: 127 GYVASKIGGKMLLGFGILGTAVLTLFTPIAADLGVGPLIVLRALEGLGEGVTFPAMHAMW 186

Query: 208 ASVYTDDEERGNVMGIALGGLAMGVLVGPPFGSVL---------YEFVGKTAPFLVLAAL 258
           +S +    ER  ++ I+  G  +G ++  P   ++         + F G    F  L  +
Sbjct: 187 SS-WAPPLERSKLLSISYAGAQLGTVISLPLSGIICYYMNWTYVFYFFGTIGIFWFLLWI 245

Query: 259 VLLDGAIQL----------FVLQPSRVQPESQKGTPLTTLLKD-PYILIAAGSICFANMG 307
            L+    Q           ++L   R Q  SQK  P   +LK  P   I      + N  
Sbjct: 246 WLVSDTPQKHKRISHYEKEYILSSLRNQLSSQKSVPWVPILKSLPLWAIVVAHFSY-NWT 304

Query: 308 IAMLEPALPIWMMETMCSRKWQLGVAFLPASISYLIGTNIFGILAHKMGRWLCALLGMII 367
              L   LP +M E +     + G  FL +S+ YL             G WLC +L    
Sbjct: 305 FYTLLTLLPTYMKEILRFNVQENG--FL-SSLPYL-------------GSWLCMILSGQA 348

Query: 368 V-------GVSILCIPFAKNIYGLIAP 387
                     S LC+    ++ G+I P
Sbjct: 349 ADNLRAKWNFSTLCVRRIFSLIGMIGP 375


>gi|42475555 monocarboxylate transporter 13 [Homo sapiens]
          Length = 426

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 69/316 (21%), Positives = 126/316 (39%), Gaps = 17/316 (5%)

Query: 141 VQLITNPFIGLLTNRIGYPIPIFAGFCIMFVSTIMFAFSSSYAFLLIARSL-QGIGSSCS 199
           VQ   +P    L+ + G    +  G  +  +  ++ +F++S   L ++  L  G G + +
Sbjct: 62  VQQFGSPVGSALSTKFGPRPVVMTGGILAALGMLLASFATSLTHLYLSIGLLSGSGWALT 121

Query: 200 SVAGMGMLASVYTDDEERGNVMGIALGGLAMGVLVGPPFGSVLYEFVGKTAPFLVLAALV 259
               +  L+  ++    R    G+AL G+ +      PF   L          L+++AL 
Sbjct: 122 FAPTLACLSCYFS--RRRSLATGLALTGVGLSSFTFAPFFQWLLSHYAWRGSLLLVSALS 179

Query: 260 LLDGAIQLFVLQPSRVQPESQKG--TPLTTLLKDPYILIAAGSICFANMGIAMLEPALPI 317
           L   A    +  PS  +  +  G    LT+LL     L    ++   N G  +  P L +
Sbjct: 180 LHLVACGALLRPPSLAEDPAVGGPRAQLTSLLHHGPFLRYTVALTLINTGYFI--PYLHL 237

Query: 318 WMMETMCSRKWQ-LGVAFLPA--SISYLIGTNIFGILAHKMGRWLCALLGM--IIVGVSI 372
             +  +    W  L  AFL +  +IS L+G  + G L   +   +  LL +   + GVS+
Sbjct: 238 --VAHLQDLDWDPLPAAFLLSVVAISDLVGRVVSGWLGDAVPGPVTRLLMLWTTLTGVSL 295

Query: 373 LCIPFAKNIYGLIAPNFGVGFAIGMVDSSMMPIMGYLVDLRHVSVYGSVYAIADVAFCMG 432
              P A+    L+A     GF  G +      ++  L+  R   +Y  +  +  +   +G
Sbjct: 296 ALFPVAQAPTALVALAVAYGFTSGALAPLAFSVLPELIGTRR--IYCGL-GLLQMIESIG 352

Query: 433 YAIGPSAGGAIAKAIG 448
             +GP   G +    G
Sbjct: 353 GLLGPPLSGYLRDVTG 368


>gi|34916028 solute carrier family 16 (monocarboxylic acid
           transporters), member 9 [Homo sapiens]
          Length = 509

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 29/121 (23%), Positives = 56/121 (46%), Gaps = 3/121 (2%)

Query: 141 VQLITNPFIGLLTNRIGY-PIPIFAGFCIMFVSTIMFAFSSSYAFLLIARSLQGIGSSCS 199
           V L+ +P   L  +  G  P+ IF+GF +     ++ +F+ +  FL  +  +  +G  C 
Sbjct: 61  VGLLASPVCSLCVSSFGARPVTIFSGFMVAG-GLMLSSFAPNIYFLFFSYGIV-VGLGCG 118

Query: 200 SVAGMGMLASVYTDDEERGNVMGIALGGLAMGVLVGPPFGSVLYEFVGKTAPFLVLAALV 259
            +    +  +    D+ RG  +G+   G ++G+ +      +L EF G     L++ AL 
Sbjct: 119 LLYTATVTITCQYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALA 178

Query: 260 L 260
           L
Sbjct: 179 L 179


>gi|148743791 solute carrier family 17 (sodium phosphate), member 3
           isoform a [Homo sapiens]
          Length = 498

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 67/326 (20%), Positives = 132/326 (40%), Gaps = 38/326 (11%)

Query: 52  KHEKNATEIQ---TARPVHTASISDSFQSI--FSYYDNSTMVTGNATRDLTL----HQTA 102
           +  KNA ++Q   T  P    S+  +   I    ++ N T +  N   ++T+    + T+
Sbjct: 12  RESKNAQDMQVDETLIPRKVPSLCSARYGIALVLHFCNFTTIAQNVIMNITMVAMVNSTS 71

Query: 103 TQHMVTNASAV------------PSDCPSEDKDLLNENVQV-GLLFASKATVQLITNPFI 149
            Q  + ++S V            P   P++   + + + Q+ G++F +     ++T    
Sbjct: 72  PQSQLNDSSEVLPVDSFGGLSKAPKSLPAK-APVYDWSPQIQGIIFGAVGYGGILTMAPS 130

Query: 150 GLLTNRIGYPIPI-FAGFCIMFVST-IMFAFSSSYAFLLIARSLQGIGSSCSSVAGMGML 207
           G L  R+G    +  + F   F++  I  A       L++ R +QG+  S S + G   +
Sbjct: 131 GYLAGRVGTKRVVGISLFATSFLTLCIPLATDFGIVLLIVTRIVQGLSQS-SILGGQFAI 189

Query: 208 ASVYTDDEERGNVMGIALGGLAMGVLVGPPFGSVLYEFVGKTAPFLVLAALVLLDGAIQL 267
              +   +ER  +  IAL G+ +G       G  + E +G    F +   +  +   +  
Sbjct: 190 WEKWGPPQERSRLCSIALSGMLLGCFTAILIGGFISETLGWPFVFYIFGGVGCVCCLLWF 249

Query: 268 FVLQPSRVQPESQKGTPLTTLLKDPYILIAAGSICFAN---MGIAMLEPALPIWMMETMC 324
            V+    V        P  +  +  YI+ +      ++   + I  +  +LPIW +   C
Sbjct: 250 VVIYDDPV------SYPWISTSEKEYIISSLKQQVGSSKQPLPIKAMLRSLPIWSICLGC 303

Query: 325 -SRKWQLG--VAFLPASISYLIGTNI 347
            S +W +   V ++P  IS +   NI
Sbjct: 304 FSHQWLVSTMVVYIPTYISSVYHVNI 329


>gi|213021148 SVOP-like isoform 1 [Homo sapiens]
          Length = 492

 Score = 39.3 bits (90), Expect = 0.009
 Identities = 37/166 (22%), Positives = 67/166 (40%), Gaps = 26/166 (15%)

Query: 306 MGIAMLEPALPI-WMMETMCSRKWQLGVAFLPASISYLIGTNIFGILAHKMGRWLCALLG 364
           M IA++ P +   W +E      WQ+ +        Y++ + +FG+LA + GRW   L+ 
Sbjct: 66  MLIAVVSPVIRCEWQLEN-----WQVALVTTMVFFGYMVFSILFGLLADRYGRWKILLIS 120

Query: 365 MIIVGVSILCIPFAKNIYGLIAPNFGVGFAIG------MVDSSMMP--IMGYLVDLRHVS 416
            +      L   FA +    +     VG  +       ++ +  +P    GY++ L    
Sbjct: 121 FLWGAYFSLLTSFAPSYIWFVFLRTMVGCGVSGHSQGLIIKTEFLPTKYRGYMLPL---- 176

Query: 417 VYGSVYAIADVAFCMGYAIGPSAGGAIAKAIGFPWLMTIIGIIDIL 462
               V+ +A     +G A        I   IG+ WL+ +  I  I+
Sbjct: 177 --SQVFWLAGSLLIIGLA------SVIIPTIGWRWLIRVASIPGII 214


>gi|23510410 solute carrier family 22 member 1 isoform b [Homo
           sapiens]
          Length = 506

 Score = 38.5 bits (88), Expect = 0.015
 Identities = 30/114 (26%), Positives = 52/114 (45%), Gaps = 11/114 (9%)

Query: 94  RDLTLHQTATQHMVTNASAVPSDCPSEDKDLLNENVQVGLLFASKATVQLITNPFIGLLT 153
           +D  ++ T    +VT  + V +D  S   DL    +  G LF S           +G   
Sbjct: 122 QDGWVYDTPGSSIVTEFNLVCAD--SWKLDLFQSCLNAGFLFGSLG---------VGYFA 170

Query: 154 NRIGYPIPIFAGFCIMFVSTIMFAFSSSYAFLLIARSLQGIGSSCSSVAGMGML 207
           +R G  + +     +  VS ++ AFS +Y  +L+ R LQG+ S  + +AG  ++
Sbjct: 171 DRFGRKLCLLGTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLI 224



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 33/142 (23%), Positives = 61/142 (42%), Gaps = 8/142 (5%)

Query: 323 MCSRKWQLGVAFLPASISYLIGTNIFGILAHKMGRWLCALLGMIIVGVSILCIPFAKNIY 382
           +C+  W+L +     +  +L G+   G  A + GR LC L  +++  VS + + F+ N  
Sbjct: 141 VCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLLGTVLVNAVSGVLMAFSPNYM 200

Query: 383 GLIAPNFGVGFAIGMVDSSMMPIMGYLVDLRHVSVYGSVYAIADVAFCMGYAIGPSAGGA 442
            ++      G       S    + GY +    V   GS   +A + + M + +G  A   
Sbjct: 201 SMLLFRLLQGLV-----SKGNWMAGYTLITEFVG-SGSRRTVA-IMYQMAFTVGLVALTG 253

Query: 443 IAKAI-GFPWLMTIIGIIDILF 463
           +A A+  + WL   + +   LF
Sbjct: 254 LAYALPHWRWLQLAVSLPTFLF 275


>gi|4506999 solute carrier family 22 member 1 isoform a [Homo
           sapiens]
          Length = 554

 Score = 38.5 bits (88), Expect = 0.015
 Identities = 30/114 (26%), Positives = 52/114 (45%), Gaps = 11/114 (9%)

Query: 94  RDLTLHQTATQHMVTNASAVPSDCPSEDKDLLNENVQVGLLFASKATVQLITNPFIGLLT 153
           +D  ++ T    +VT  + V +D  S   DL    +  G LF S           +G   
Sbjct: 122 QDGWVYDTPGSSIVTEFNLVCAD--SWKLDLFQSCLNAGFLFGSLG---------VGYFA 170

Query: 154 NRIGYPIPIFAGFCIMFVSTIMFAFSSSYAFLLIARSLQGIGSSCSSVAGMGML 207
           +R G  + +     +  VS ++ AFS +Y  +L+ R LQG+ S  + +AG  ++
Sbjct: 171 DRFGRKLCLLGTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLI 224



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 33/142 (23%), Positives = 61/142 (42%), Gaps = 8/142 (5%)

Query: 323 MCSRKWQLGVAFLPASISYLIGTNIFGILAHKMGRWLCALLGMIIVGVSILCIPFAKNIY 382
           +C+  W+L +     +  +L G+   G  A + GR LC L  +++  VS + + F+ N  
Sbjct: 141 VCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLLGTVLVNAVSGVLMAFSPNYM 200

Query: 383 GLIAPNFGVGFAIGMVDSSMMPIMGYLVDLRHVSVYGSVYAIADVAFCMGYAIGPSAGGA 442
            ++      G       S    + GY +    V   GS   +A + + M + +G  A   
Sbjct: 201 SMLLFRLLQGLV-----SKGNWMAGYTLITEFVG-SGSRRTVA-IMYQMAFTVGLVALTG 253

Query: 443 IAKAI-GFPWLMTIIGIIDILF 463
           +A A+  + WL   + +   LF
Sbjct: 254 LAYALPHWRWLQLAVSLPTFLF 275


>gi|157041233 solute carrier family 16 (monocarboxylic acid
           transporters), member 12 [Homo sapiens]
          Length = 486

 Score = 38.1 bits (87), Expect = 0.019
 Identities = 68/350 (19%), Positives = 134/350 (38%), Gaps = 51/350 (14%)

Query: 141 VQLITNPFIGLLTNRIGYPIPIFAGFCIMFVSTIMFAFSSSYAFLLIARS-LQGIGSSCS 199
           V ++  P   +++N +   + I  G  +     I+ +F++S   L +    L G+G +  
Sbjct: 67  VTMLCAPLGSVVSNHLSCQVGIMLGGLLASTGLILSSFATSLKHLYLTLGVLTGLGFALC 126

Query: 200 SVAGMGMLASVYTDDEERGNVMGIALGGLAMGVLVGPPFGSVLYEFVGKTAPFLVLAALV 259
               + M+   ++    +    GIA+ G  +G  +  P   +L E        L+L   V
Sbjct: 127 YSPAIAMVGKYFS--RRKALAYGIAMSGSGIGTFILAPVVQLLIEQFSWRGALLILGGFV 184

Query: 260 L---LDGAI-QLFVLQPSRVQPES-----------QKGTPLTTLLKD------------- 291
           L   + GA+ +   L+     PE            ++ +P ++L K+             
Sbjct: 185 LNLCVCGALMRPITLKEDHTTPEQNHVCRTQKEDIKRVSPYSSLTKEWAQTCLCCCLQQE 244

Query: 292 ------PYILIAAGSICFANMGIAMLEPALPIWMMETMCSRKWQLGVAFLPASISY--LI 343
                    ++ A S+ F   G + L   L  + +    S +     AFL + +    +I
Sbjct: 245 YSFLLMSDFVVLAVSVLFMAYGCSPLFVYLVPYALSVGVSHQ---QAAFLMSILGVIDII 301

Query: 344 GTNIFGILAH----KMGRWLCALLGMIIVGVSILCIPFAKNIYGLIAPNFGVGFAIGMVD 399
           G   FG L      K  +++C L  + + G+  LC+P  +++  L+  +   G+  G   
Sbjct: 302 GNITFGWLTDRRCLKNYQYVCYLFAVGMDGLCYLCLPMLQSLPLLVPFSCTFGYFDGAYV 361

Query: 400 SSMMPIMGYLVDLRHV-SVYGSVYAIADVAFCMGYAIGPSAGGAIAKAIG 448
           + +  +   +V    + S  G VY +  V     Y + P   G +    G
Sbjct: 362 TLIPVVTTEIVGTTSLSSALGVVYFLHAVP----YLVSPPIAGRLVDTTG 407


>gi|225703102 major facilitator superfamily domain containing 10
           [Homo sapiens]
          Length = 455

 Score = 37.0 bits (84), Expect = 0.043
 Identities = 35/155 (22%), Positives = 63/155 (40%), Gaps = 9/155 (5%)

Query: 330 LGVAFLPASISYLIGTNIFGILAHKMGRWLCALLGMIIVGVSILCIPFAKNIYGLIAPNF 389
           +G AF   S+   +   + G  +  +GR    LL ++ V  S      +++    +A   
Sbjct: 92  IGSAF---SVLQFLCAPLTGATSDCLGRRPVMLLCLMGVATSYAVWATSRSFAAFLASRL 148

Query: 390 GVGFAIGMVDSSMMPIMGYLVDLRHVSVYGSVYAIADVAFCMGYAIGPSAGGAIAKAIGF 449
             G + G V  S       + DL          A+  VAF +G+ +GP  G ++   +  
Sbjct: 149 IGGISKGNVSLST----AIVADLGSPLARSQGMAVIGVAFSLGFTLGPMLGASLPLEMA- 203

Query: 450 PWLMTIIGIIDILFAPLCFFLRSPPAKEEKMAILM 484
           PW   +    D+LF   CF   + P ++   +I +
Sbjct: 204 PWFALLFAASDLLFI-FCFLPETLPLEKRAPSIAL 237



 Score = 30.0 bits (66), Expect = 5.3
 Identities = 12/29 (41%), Positives = 21/29 (72%)

Query: 22 ILFIVFLALLLDNMLLTVVVPIIPSYLYS 50
          ++ +VFL LLLD +  T+++P++P  L S
Sbjct: 24 VVTVVFLGLLLDLLAFTLLLPLLPGLLES 52


>gi|225703104 major facilitator superfamily domain containing 10
           [Homo sapiens]
          Length = 455

 Score = 37.0 bits (84), Expect = 0.043
 Identities = 35/155 (22%), Positives = 63/155 (40%), Gaps = 9/155 (5%)

Query: 330 LGVAFLPASISYLIGTNIFGILAHKMGRWLCALLGMIIVGVSILCIPFAKNIYGLIAPNF 389
           +G AF   S+   +   + G  +  +GR    LL ++ V  S      +++    +A   
Sbjct: 92  IGSAF---SVLQFLCAPLTGATSDCLGRRPVMLLCLMGVATSYAVWATSRSFAAFLASRL 148

Query: 390 GVGFAIGMVDSSMMPIMGYLVDLRHVSVYGSVYAIADVAFCMGYAIGPSAGGAIAKAIGF 449
             G + G V  S       + DL          A+  VAF +G+ +GP  G ++   +  
Sbjct: 149 IGGISKGNVSLST----AIVADLGSPLARSQGMAVIGVAFSLGFTLGPMLGASLPLEMA- 203

Query: 450 PWLMTIIGIIDILFAPLCFFLRSPPAKEEKMAILM 484
           PW   +    D+LF   CF   + P ++   +I +
Sbjct: 204 PWFALLFAASDLLFI-FCFLPETLPLEKRAPSIAL 237



 Score = 30.0 bits (66), Expect = 5.3
 Identities = 12/29 (41%), Positives = 21/29 (72%)

Query: 22 ILFIVFLALLLDNMLLTVVVPIIPSYLYS 50
          ++ +VFL LLLD +  T+++P++P  L S
Sbjct: 24 VVTVVFLGLLLDLLAFTLLLPLLPGLLES 52


>gi|4507001 solute carrier family 22 member 2 [Homo sapiens]
          Length = 555

 Score = 36.6 bits (83), Expect = 0.056
 Identities = 32/134 (23%), Positives = 57/134 (42%), Gaps = 11/134 (8%)

Query: 70  SISDSFQSIFSYYDNSTMVTGNATRDLTLHQTATQHMVTNASAVPSDCPSEDKDLLNENV 129
           S  D    + S   N + +     RD  +++T    +VT  + V ++  S   DL   +V
Sbjct: 99  STFDCVDPLASLDTNRSRLPLGPCRDGWVYETPGSSIVTEFNLVCAN--SWMLDLFQSSV 156

Query: 130 QVGLLFASKATVQLITNPFIGLLTNRIGYPIPIFAGFCIMFVSTIMFAFSSSYAFLLIAR 189
            VG    S +         IG + +R G  + +     I   + ++ A S +Y ++LI R
Sbjct: 157 NVGFFIGSMS---------IGYIADRFGRKLCLLTTVLINAAAGVLMAISPTYTWMLIFR 207

Query: 190 SLQGIGSSCSSVAG 203
            +QG+ S    + G
Sbjct: 208 LIQGLVSKAGWLIG 221



 Score = 34.7 bits (78), Expect = 0.21
 Identities = 39/174 (22%), Positives = 68/174 (39%), Gaps = 37/174 (21%)

Query: 311 LEPALPIWMMET-----------MCSRKWQLGVAFLPASISYLIGTNIFGILAHKMGRWL 359
           L P    W+ ET           +C+  W L +     ++ + IG+   G +A + GR L
Sbjct: 119 LGPCRDGWVYETPGSSIVTEFNLVCANSWMLDLFQSSVNVGFFIGSMSIGYIADRFGRKL 178

Query: 360 CALLGMII---VGVSILCIP------FAKNIYGLIAPNFGVGFAIGMVDSSMMPIMGYLV 410
           C L  ++I    GV +   P        + I GL++     G+ IG +      ++   V
Sbjct: 179 CLLTTVLINAAAGVLMAISPTYTWMLIFRLIQGLVSK---AGWLIGYI------LITEFV 229

Query: 411 DLRHVSVYGSVYAIADVAFCMGYAIGPSAGGAIAKAI-GFPWLMTIIGIIDILF 463
             R+    G  Y +A       Y +G      +A A+  + WL   + + +  F
Sbjct: 230 GRRYRRTVGIFYQVA-------YTVGLLVLAGVAYALPHWRWLQFTVALPNFFF 276


>gi|5730045 solute carrier family 16, member 2 [Homo sapiens]
          Length = 613

 Score = 36.6 bits (83), Expect = 0.056
 Identities = 72/352 (20%), Positives = 128/352 (36%), Gaps = 41/352 (11%)

Query: 146 NPFIGLLTNRIGYPIPIFAGFCIMFVSTIMFAFSSSYAFLLIARSLQGIGSSCSSVAGMG 205
           +P + + T+R+G  I   AG  + F+     +F+SS +       +   G  CS      
Sbjct: 232 SPIVSIFTDRLGCRITATAGAAVAFIGLHTSSFTSSLSLRYFTYGIL-FGCGCSFAFQPS 290

Query: 206 MLASVYTDDEERGNVMGIALGGLAMGVLVGPPFGSVLYEFVGKTAPFLVLAAL--VLLDG 263
           ++   +      G   G+   G ++  +  P    +L + +     F VL+    VL+  
Sbjct: 291 LVILGHYFQRRLGLANGVVSAGSSIFSMSFPFLIRMLGDKIKLAQTFQVLSTFMFVLMLL 350

Query: 264 AIQLFVLQPSRVQPESQKGTPLT--------------TLLKDPYILIAAGSICFANMGIA 309
           ++    L PS     S++G                   + +     I A  I  A +G  
Sbjct: 351 SLTYRPLLPSSQDTPSKRGVRTLHQRFLAQLRKYFNMRVFRQRTYRIWAFGIAAAALGYF 410

Query: 310 MLEPALPIWMMETMCSRK--WQLGVAFLPAS-ISYLIGTNIFGILAHKMGRWLCALLGMI 366
           +    L  ++ E     K  W L V     S +  L+  +I   +      +L  +L  +
Sbjct: 411 VPYVHLMKYVEEEFSEIKETWVLLVCIGATSGLGRLVSGHISDSIPGLKKIYL-QVLSFL 469

Query: 367 IVGVSILCIPFAKNIYGLIAPNFGVGFAIGMVDSSMMPIMGYLVDLRHVSVYGSVYAIAD 426
           ++G+  + IP  ++  GLI     +G   G   + M PI   LV        G + A   
Sbjct: 470 LLGLMSMMIPLCRDFGGLIVVCLFLGLCDGFFITIMAPIAFELV--------GPMQASQA 521

Query: 427 VAFCMG-----YAIGPSAGGAIAKAIG-------FPWLMTIIGIIDILFAPL 466
           + + +G        GP   G +    G       F  +  IIG + + F PL
Sbjct: 522 IGYLLGMMALPMIAGPPIAGLLRNCFGDYHVAFYFAGVPPIIGAVILFFVPL 573


>gi|24431958 solute carrier family 16, member 7 [Homo sapiens]
          Length = 478

 Score = 35.8 bits (81), Expect = 0.096
 Identities = 26/115 (22%), Positives = 51/115 (44%), Gaps = 3/115 (2%)

Query: 147 PFIGLLTNRIGYPIPIFAGFCIMFVSTIMFAFSSSYAFLLIARS-LQGIGSSCSSVAGMG 205
           P   +L N+ G    + AG  +  +  ++ +FSSS   L +    + G+G + +    + 
Sbjct: 74  PVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFITGLGLAFNLQPALT 133

Query: 206 MLASVYTDDEERGNVMGIALGGLAMGVLVGPPFGSVLYEFVGKTAPFLVLAALVL 260
           ++   +       N  G+A+ G  + +    PF   L+   G    FL+L +L+L
Sbjct: 134 IIGKYFYRKRPMAN--GLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLILGSLLL 186



 Score = 33.5 bits (75), Expect = 0.48
 Identities = 44/175 (25%), Positives = 73/175 (41%), Gaps = 15/175 (8%)

Query: 122 KDLLNENVQVGLLFASKATVQLITNPFIGLLTNR--IGYPIPIFAGFCIMF--VSTIMFA 177
           KD   +      L +  A V +   P +GL+ N   I   I  F  F IMF  V  ++  
Sbjct: 273 KDQGIDEYSAAFLLSVMAFVDMFARPSVGLIANSKYIRPRIQYFFSFAIMFNGVCHLLCP 332

Query: 178 FSSSYAFLLIARSLQGIG-SSCSSVAGMGMLASVYTDDEERGNVMGIALGGLAMGVLVGP 236
            +  Y  L++     G+G  S SSV    ++  V        + +G+        VL+GP
Sbjct: 333 LAQDYTSLVLYAVFFGLGFGSVSSVLFETLMDLVGAP--RFSSAVGLVTIVECGPVLLGP 390

Query: 237 PFGSVL------YEFVGKTAPFLVLAALV--LLDGAIQLFVLQPSRVQPESQKGT 283
           P    L      Y+++  +   +V+AA V  L+  AI   +L   R +  +++ T
Sbjct: 391 PLAGKLVDLTGEYKYMYMSCGAIVVAASVWLLIGNAINYRLLAKERKEENARQKT 445


>gi|21553331 solute carrier family 2 (facilitated glucose
           transporter), member 12 [Homo sapiens]
          Length = 617

 Score = 35.8 bits (81), Expect = 0.096
 Identities = 25/113 (22%), Positives = 53/113 (46%), Gaps = 10/113 (8%)

Query: 121 DKDLLNENVQVGLLFASKATVQLITNPFIGLLTNRIGYPIPIFAGFCIMFVSTIMFAFSS 180
           +++++  ++ +G L AS            G+L +R G    I    C++ + +++   S 
Sbjct: 78  EQEMVVSSLVIGALLASLTG---------GVLIDRYGRRTAIILSSCLLGLGSLVLILSL 128

Query: 181 SYAFLLIARSLQGIGSSCSSVAGMGMLASVYTDDEERGNVMGIALGGLAMGVL 233
           SY  L++ R   G+  S SS+A    +A +      RG ++ +    + +G+L
Sbjct: 129 SYTVLIVGRIAIGVSISLSSIATCVYIAEI-APQHRRGLLVSLNELMIVIGIL 180


>gi|109288010 solute carrier family 16, member 3 [Homo sapiens]
          Length = 465

 Score = 35.4 bits (80), Expect = 0.13
 Identities = 71/345 (20%), Positives = 129/345 (37%), Gaps = 33/345 (9%)

Query: 145 TNPFIGLLTNRIGY-PIPIFAGFCIMFVSTIMFAFSSSYAFL---LIARSLQGIGSSCSS 200
           T P   +  NR G  P+ +  G   +F S  M A S   + +   L    + G+G + + 
Sbjct: 74  TGPLCSVCVNRFGCRPVMLVGG---LFASLGMVAASFCRSIIQVYLTTGVITGLGLALNF 130

Query: 201 VAGMGMLASVYTDDEERGNVMGIALGGLAMGVLVGPPFGSVLYEFVGKTAPFLVLAALVL 260
              + ML   ++      N  G+A  G  + +    P G +L +  G    FL+L  L L
Sbjct: 131 QPSLIMLNRYFSKRRPMAN--GLAAAGSPVFLCALSPLGQLLQDRYGWRGGFLILGGL-L 187

Query: 261 LDGAIQLFVLQPSRVQPESQKGTPL-TTLLKDPYILIAAGSICFANMGIAMLEPAL--PI 317
           L+  +   +++P  V  +   G P  +  L D  +    G + +A     M+      P+
Sbjct: 188 LNCCVCAALMRPLVVTAQPGSGPPRPSRRLLDLSVFRDRGFVLYAVAASVMVLGLFVPPV 247

Query: 318 WMMETMCSRKWQLGVAFLPASISYLIGTNIFGILAHKMGRWLCAL------------LGM 365
           +++    S    LGV    A+    I      I A     ++  L              M
Sbjct: 248 FVV----SYAKDLGVPDTKAAFLLTI-LGFIDIFARPAAGFVAGLGKVRPYSVYLFSFSM 302

Query: 366 IIVGVSILCIPFAKNIYGLIAPNFGVGFAIGMVDSSMMPIMGYLVDLRHVSVYGSVYAIA 425
              G++ L    A +  GL+      G + GMV +    ++  +V       + S   + 
Sbjct: 303 FFNGLADLAGSTAGDYGGLVVFCIFFGISYGMVGALQFEVLMAIVGTHK---FSSAIGLV 359

Query: 426 DVAFCMGYAIGPSAGGAIAKAIGFPWLMTIIGIIDILFAPLCFFL 470
            +   +   +GP +GG +  A      + I+   ++L + L   L
Sbjct: 360 LLMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAEVLTSSLILLL 404



 Score = 32.0 bits (71), Expect = 1.4
 Identities = 48/199 (24%), Positives = 76/199 (38%), Gaps = 18/199 (9%)

Query: 94  RDLTLHQTATQHMVTNASAVPSDCPSEDKDLLNENVQVGLLFASKATVQLITNPFIGLLT 153
           R   L+  A   MV      P    S  KDL   + +   L      + +   P  G + 
Sbjct: 226 RGFVLYAVAASVMVLGLFVPPVFVVSYAKDLGVPDTKAAFLLTILGFIDIFARPAAGFVA 285

Query: 154 NRIG----YPIPIFAGFCIMFVSTIMFAFSSS--YAFLLIARSLQGIGSSCSSVAGMGML 207
             +G    Y + +F+ F + F      A S++  Y  L++     GI           +L
Sbjct: 286 G-LGKVRPYSVYLFS-FSMFFNGLADLAGSTAGDYGGLVVFCIFFGISYGMVGALQFEVL 343

Query: 208 ASVYTDDEERGNVMGIALGGLAMGVLVGPPFGSVL--------YEFVGKTAPFLVLAALV 259
            ++     +  + +G+ L   A+ VLVGPP G  L        Y F+   A  L  ++L+
Sbjct: 344 MAI-VGTHKFSSAIGLVLLMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAEVLT-SSLI 401

Query: 260 LLDGAIQLFVLQPSRVQPE 278
           LL G       +P   QPE
Sbjct: 402 LLLGNFFCIRKKPKEPQPE 420


>gi|109288012 solute carrier family 16, member 3 [Homo sapiens]
          Length = 465

 Score = 35.4 bits (80), Expect = 0.13
 Identities = 71/345 (20%), Positives = 129/345 (37%), Gaps = 33/345 (9%)

Query: 145 TNPFIGLLTNRIGY-PIPIFAGFCIMFVSTIMFAFSSSYAFL---LIARSLQGIGSSCSS 200
           T P   +  NR G  P+ +  G   +F S  M A S   + +   L    + G+G + + 
Sbjct: 74  TGPLCSVCVNRFGCRPVMLVGG---LFASLGMVAASFCRSIIQVYLTTGVITGLGLALNF 130

Query: 201 VAGMGMLASVYTDDEERGNVMGIALGGLAMGVLVGPPFGSVLYEFVGKTAPFLVLAALVL 260
              + ML   ++      N  G+A  G  + +    P G +L +  G    FL+L  L L
Sbjct: 131 QPSLIMLNRYFSKRRPMAN--GLAAAGSPVFLCALSPLGQLLQDRYGWRGGFLILGGL-L 187

Query: 261 LDGAIQLFVLQPSRVQPESQKGTPL-TTLLKDPYILIAAGSICFANMGIAMLEPAL--PI 317
           L+  +   +++P  V  +   G P  +  L D  +    G + +A     M+      P+
Sbjct: 188 LNCCVCAALMRPLVVTAQPGSGPPRPSRRLLDLSVFRDRGFVLYAVAASVMVLGLFVPPV 247

Query: 318 WMMETMCSRKWQLGVAFLPASISYLIGTNIFGILAHKMGRWLCAL------------LGM 365
           +++    S    LGV    A+    I      I A     ++  L              M
Sbjct: 248 FVV----SYAKDLGVPDTKAAFLLTI-LGFIDIFARPAAGFVAGLGKVRPYSVYLFSFSM 302

Query: 366 IIVGVSILCIPFAKNIYGLIAPNFGVGFAIGMVDSSMMPIMGYLVDLRHVSVYGSVYAIA 425
              G++ L    A +  GL+      G + GMV +    ++  +V       + S   + 
Sbjct: 303 FFNGLADLAGSTAGDYGGLVVFCIFFGISYGMVGALQFEVLMAIVGTHK---FSSAIGLV 359

Query: 426 DVAFCMGYAIGPSAGGAIAKAIGFPWLMTIIGIIDILFAPLCFFL 470
            +   +   +GP +GG +  A      + I+   ++L + L   L
Sbjct: 360 LLMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAEVLTSSLILLL 404



 Score = 32.0 bits (71), Expect = 1.4
 Identities = 48/199 (24%), Positives = 76/199 (38%), Gaps = 18/199 (9%)

Query: 94  RDLTLHQTATQHMVTNASAVPSDCPSEDKDLLNENVQVGLLFASKATVQLITNPFIGLLT 153
           R   L+  A   MV      P    S  KDL   + +   L      + +   P  G + 
Sbjct: 226 RGFVLYAVAASVMVLGLFVPPVFVVSYAKDLGVPDTKAAFLLTILGFIDIFARPAAGFVA 285

Query: 154 NRIG----YPIPIFAGFCIMFVSTIMFAFSSS--YAFLLIARSLQGIGSSCSSVAGMGML 207
             +G    Y + +F+ F + F      A S++  Y  L++     GI           +L
Sbjct: 286 G-LGKVRPYSVYLFS-FSMFFNGLADLAGSTAGDYGGLVVFCIFFGISYGMVGALQFEVL 343

Query: 208 ASVYTDDEERGNVMGIALGGLAMGVLVGPPFGSVL--------YEFVGKTAPFLVLAALV 259
            ++     +  + +G+ L   A+ VLVGPP G  L        Y F+   A  L  ++L+
Sbjct: 344 MAI-VGTHKFSSAIGLVLLMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAEVLT-SSLI 401

Query: 260 LLDGAIQLFVLQPSRVQPE 278
           LL G       +P   QPE
Sbjct: 402 LLLGNFFCIRKKPKEPQPE 420


>gi|4759112 solute carrier family 16, member 3 [Homo sapiens]
          Length = 465

 Score = 35.4 bits (80), Expect = 0.13
 Identities = 71/345 (20%), Positives = 129/345 (37%), Gaps = 33/345 (9%)

Query: 145 TNPFIGLLTNRIGY-PIPIFAGFCIMFVSTIMFAFSSSYAFL---LIARSLQGIGSSCSS 200
           T P   +  NR G  P+ +  G   +F S  M A S   + +   L    + G+G + + 
Sbjct: 74  TGPLCSVCVNRFGCRPVMLVGG---LFASLGMVAASFCRSIIQVYLTTGVITGLGLALNF 130

Query: 201 VAGMGMLASVYTDDEERGNVMGIALGGLAMGVLVGPPFGSVLYEFVGKTAPFLVLAALVL 260
              + ML   ++      N  G+A  G  + +    P G +L +  G    FL+L  L L
Sbjct: 131 QPSLIMLNRYFSKRRPMAN--GLAAAGSPVFLCALSPLGQLLQDRYGWRGGFLILGGL-L 187

Query: 261 LDGAIQLFVLQPSRVQPESQKGTPL-TTLLKDPYILIAAGSICFANMGIAMLEPAL--PI 317
           L+  +   +++P  V  +   G P  +  L D  +    G + +A     M+      P+
Sbjct: 188 LNCCVCAALMRPLVVTAQPGSGPPRPSRRLLDLSVFRDRGFVLYAVAASVMVLGLFVPPV 247

Query: 318 WMMETMCSRKWQLGVAFLPASISYLIGTNIFGILAHKMGRWLCAL------------LGM 365
           +++    S    LGV    A+    I      I A     ++  L              M
Sbjct: 248 FVV----SYAKDLGVPDTKAAFLLTI-LGFIDIFARPAAGFVAGLGKVRPYSVYLFSFSM 302

Query: 366 IIVGVSILCIPFAKNIYGLIAPNFGVGFAIGMVDSSMMPIMGYLVDLRHVSVYGSVYAIA 425
              G++ L    A +  GL+      G + GMV +    ++  +V       + S   + 
Sbjct: 303 FFNGLADLAGSTAGDYGGLVVFCIFFGISYGMVGALQFEVLMAIVGTHK---FSSAIGLV 359

Query: 426 DVAFCMGYAIGPSAGGAIAKAIGFPWLMTIIGIIDILFAPLCFFL 470
            +   +   +GP +GG +  A      + I+   ++L + L   L
Sbjct: 360 LLMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAEVLTSSLILLL 404



 Score = 32.0 bits (71), Expect = 1.4
 Identities = 48/199 (24%), Positives = 76/199 (38%), Gaps = 18/199 (9%)

Query: 94  RDLTLHQTATQHMVTNASAVPSDCPSEDKDLLNENVQVGLLFASKATVQLITNPFIGLLT 153
           R   L+  A   MV      P    S  KDL   + +   L      + +   P  G + 
Sbjct: 226 RGFVLYAVAASVMVLGLFVPPVFVVSYAKDLGVPDTKAAFLLTILGFIDIFARPAAGFVA 285

Query: 154 NRIG----YPIPIFAGFCIMFVSTIMFAFSSS--YAFLLIARSLQGIGSSCSSVAGMGML 207
             +G    Y + +F+ F + F      A S++  Y  L++     GI           +L
Sbjct: 286 G-LGKVRPYSVYLFS-FSMFFNGLADLAGSTAGDYGGLVVFCIFFGISYGMVGALQFEVL 343

Query: 208 ASVYTDDEERGNVMGIALGGLAMGVLVGPPFGSVL--------YEFVGKTAPFLVLAALV 259
            ++     +  + +G+ L   A+ VLVGPP G  L        Y F+   A  L  ++L+
Sbjct: 344 MAI-VGTHKFSSAIGLVLLMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAEVLT-SSLI 401

Query: 260 LLDGAIQLFVLQPSRVQPE 278
           LL G       +P   QPE
Sbjct: 402 LLLGNFFCIRKKPKEPQPE 420


>gi|41327156 solute carrier family 16 (monocarboxylic acid
           transporters), member 14 [Homo sapiens]
          Length = 510

 Score = 35.4 bits (80), Expect = 0.13
 Identities = 30/124 (24%), Positives = 53/124 (42%), Gaps = 11/124 (8%)

Query: 162 IFAGFCIMFVSTIMFAFSSSYAFLLIARSLQGIGSSCSSVAGMGMLASVYTDD----EER 217
           + A F ++ +S  +     +YA L +  +L G  S      G   L  V T+D    E  
Sbjct: 386 LLANFTLV-LSIFILPLMHTYAGLAVICALIGFSS------GYFSLMPVVTEDLVGIEHL 438

Query: 218 GNVMGIALGGLAMGVLVGPPFGSVLYEFVGKTAPFLVLAALVLLDGAIQLFVLQPSRVQP 277
            N  GI +    +  L+GPPF   +Y+   K      +  L+ + G + L +    R+  
Sbjct: 439 ANAYGIIICANGISALLGPPFAGWIYDITQKYDFSFYICGLLYMIGILFLLIQPCIRIIE 498

Query: 278 ESQK 281
           +S++
Sbjct: 499 QSRR 502



 Score = 32.0 bits (71), Expect = 1.4
 Identities = 21/95 (22%), Positives = 42/95 (44%), Gaps = 3/95 (3%)

Query: 141 VQLITNPFIGLLTNRIGYPIPIFAGFCIMFVSTIMFAFSSSYAFLLIARSL-QGIGSSCS 199
           + LI  PFIGL  N  G       G  +  +  ++ A++++  +L I   +  G+GS  +
Sbjct: 82  ITLIVGPFIGLFINTCGCRQTAIIGGLVNSLGWVLSAYAANVHYLFITFGVAAGLGSGMA 141

Query: 200 SVAGMGMLASVYTDDEERGNVMGIALGGLAMGVLV 234
            +  + M+   +   + R    G++  G   G  +
Sbjct: 142 YLPAVVMVGRYF--QKRRALAQGLSTTGTGFGTFL 174


>gi|24497480 solute carrier family 22 member 6 isoform d [Homo
           sapiens]
          Length = 519

 Score = 34.7 bits (78), Expect = 0.21
 Identities = 29/128 (22%), Positives = 50/128 (39%), Gaps = 16/128 (12%)

Query: 313 PALPIWMMETMCSRKWQLGVAFLPASISYLIGTNIFGILAHKMGRWLCALLGMIIVGVSI 372
           P+  +   + +CS +    +A     +  L+G  +FG LA ++GR    +L  +   VS 
Sbjct: 117 PSTIVTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSG 176

Query: 373 LCIPFAKNIYGLIAPNFGVGFAIGMVDSSMM----------------PIMGYLVDLRHVS 416
            C  FA N     A     G A+  +  + M                 ++GY+  L    
Sbjct: 177 TCAAFAPNFPIYCAFRLLSGMALAGISLNCMTLNVEWMPIHTRACVGTLIGYVYSLGQFL 236

Query: 417 VYGSVYAI 424
           + G  YA+
Sbjct: 237 LAGVAYAV 244


>gi|24497478 solute carrier family 22 member 6 isoform c [Homo
           sapiens]
          Length = 506

 Score = 34.7 bits (78), Expect = 0.21
 Identities = 29/128 (22%), Positives = 50/128 (39%), Gaps = 16/128 (12%)

Query: 313 PALPIWMMETMCSRKWQLGVAFLPASISYLIGTNIFGILAHKMGRWLCALLGMIIVGVSI 372
           P+  +   + +CS +    +A     +  L+G  +FG LA ++GR    +L  +   VS 
Sbjct: 117 PSTIVTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSG 176

Query: 373 LCIPFAKNIYGLIAPNFGVGFAIGMVDSSMM----------------PIMGYLVDLRHVS 416
            C  FA N     A     G A+  +  + M                 ++GY+  L    
Sbjct: 177 TCAAFAPNFPIYCAFRLLSGMALAGISLNCMTLNVEWMPIHTRACVGTLIGYVYSLGQFL 236

Query: 417 VYGSVYAI 424
           + G  YA+
Sbjct: 237 LAGVAYAV 244


>gi|24497476 solute carrier family 22 member 6 isoform b [Homo
           sapiens]
          Length = 550

 Score = 34.7 bits (78), Expect = 0.21
 Identities = 29/128 (22%), Positives = 50/128 (39%), Gaps = 16/128 (12%)

Query: 313 PALPIWMMETMCSRKWQLGVAFLPASISYLIGTNIFGILAHKMGRWLCALLGMIIVGVSI 372
           P+  +   + +CS +    +A     +  L+G  +FG LA ++GR    +L  +   VS 
Sbjct: 117 PSTIVTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSG 176

Query: 373 LCIPFAKNIYGLIAPNFGVGFAIGMVDSSMM----------------PIMGYLVDLRHVS 416
            C  FA N     A     G A+  +  + M                 ++GY+  L    
Sbjct: 177 TCAAFAPNFPIYCAFRLLSGMALAGISLNCMTLNVEWMPIHTRACVGTLIGYVYSLGQFL 236

Query: 417 VYGSVYAI 424
           + G  YA+
Sbjct: 237 LAGVAYAV 244


>gi|20070188 solute carrier family 22 member 6 isoform a [Homo
           sapiens]
          Length = 563

 Score = 34.7 bits (78), Expect = 0.21
 Identities = 29/128 (22%), Positives = 50/128 (39%), Gaps = 16/128 (12%)

Query: 313 PALPIWMMETMCSRKWQLGVAFLPASISYLIGTNIFGILAHKMGRWLCALLGMIIVGVSI 372
           P+  +   + +CS +    +A     +  L+G  +FG LA ++GR    +L  +   VS 
Sbjct: 117 PSTIVTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSG 176

Query: 373 LCIPFAKNIYGLIAPNFGVGFAIGMVDSSMM----------------PIMGYLVDLRHVS 416
            C  FA N     A     G A+  +  + M                 ++GY+  L    
Sbjct: 177 TCAAFAPNFPIYCAFRLLSGMALAGISLNCMTLNVEWMPIHTRACVGTLIGYVYSLGQFL 236

Query: 417 VYGSVYAI 424
           + G  YA+
Sbjct: 237 LAGVAYAV 244


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.139    0.417 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,869,929
Number of Sequences: 37866
Number of extensions: 756558
Number of successful extensions: 2467
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 31
Number of HSP's that attempted gapping in prelim test: 2360
Number of HSP's gapped (non-prelim): 107
length of query: 514
length of database: 18,247,518
effective HSP length: 107
effective length of query: 407
effective length of database: 14,195,856
effective search space: 5777713392
effective search space used: 5777713392
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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