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Search of human proteins with 42476130
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|42476130 ubiquitin interaction motif containing 1 [Homo
sapiens]
(719 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|42476130 ubiquitin interaction motif containing 1 [Homo sapiens] 1437 0.0
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 42 0.002
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 42 0.002
gi|219842214 protein phosphatase 1, regulatory (inhibitor) subun... 42 0.002
gi|219842212 protein phosphatase 1, regulatory (inhibitor) subun... 42 0.002
gi|4505317 protein phosphatase 1, regulatory (inhibitor) subunit... 42 0.002
gi|74136549 AT rich interactive domain 5B (MRF1-like) [Homo sapi... 42 0.002
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 41 0.003
gi|21735569 claspin [Homo sapiens] 40 0.008
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 40 0.008
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 40 0.008
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 40 0.008
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 40 0.008
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 40 0.008
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 40 0.008
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 40 0.008
gi|6005757 chromatin-specific transcription elongation factor la... 40 0.010
gi|189011568 adenomatous polyposis coli [Homo sapiens] 40 0.010
gi|189011566 adenomatous polyposis coli [Homo sapiens] 40 0.010
gi|53759122 adenomatous polyposis coli [Homo sapiens] 40 0.010
gi|210032580 SET domain containing 1B [Homo sapiens] 40 0.010
gi|114205399 cyclic nucleotide gated channel beta 1 isoform a [H... 39 0.013
gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens] 39 0.013
gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens] 39 0.013
gi|24308089 chromodomain helicase DNA binding protein 5 [Homo sa... 39 0.013
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 39 0.022
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 38 0.037
gi|157502225 Janus kinase and microtubule interacting protein 3 ... 38 0.037
gi|22538461 nuclear receptor co-repressor 1 [Homo sapiens] 38 0.037
gi|34482047 adaptor-related protein complex 3, beta 2 subunit [H... 38 0.037
>gi|42476130 ubiquitin interaction motif containing 1 [Homo sapiens]
Length = 719
Score = 1437 bits (3720), Expect = 0.0
Identities = 719/719 (100%), Positives = 719/719 (100%)
Query: 1 MPRRKKKVKEVSESRNLEKKDVETTSSVSVKRKRRLEDAFIVISDSDGEEPKEENGLQKT 60
MPRRKKKVKEVSESRNLEKKDVETTSSVSVKRKRRLEDAFIVISDSDGEEPKEENGLQKT
Sbjct: 1 MPRRKKKVKEVSESRNLEKKDVETTSSVSVKRKRRLEDAFIVISDSDGEEPKEENGLQKT 60
Query: 61 KTKQSNRAKCLAKRKIAQMTEEEQFALALKMSEQEAREVNSQEEEEEELLRKAIAESLNS 120
KTKQSNRAKCLAKRKIAQMTEEEQFALALKMSEQEAREVNSQEEEEEELLRKAIAESLNS
Sbjct: 61 KTKQSNRAKCLAKRKIAQMTEEEQFALALKMSEQEAREVNSQEEEEEELLRKAIAESLNS 120
Query: 121 CRPSDASATRSRPLATGPSSQSHQEKTTDSGLTEGIWQLVPPSLFKGSHISQGNEAEERE 180
CRPSDASATRSRPLATGPSSQSHQEKTTDSGLTEGIWQLVPPSLFKGSHISQGNEAEERE
Sbjct: 121 CRPSDASATRSRPLATGPSSQSHQEKTTDSGLTEGIWQLVPPSLFKGSHISQGNEAEERE 180
Query: 181 EPWDHTEKTEEEPVSGSSGSWDQSSQPVFENVNVKSFDRCTGHSAEHTQCGKPQESTGRG 240
EPWDHTEKTEEEPVSGSSGSWDQSSQPVFENVNVKSFDRCTGHSAEHTQCGKPQESTGRG
Sbjct: 181 EPWDHTEKTEEEPVSGSSGSWDQSSQPVFENVNVKSFDRCTGHSAEHTQCGKPQESTGRG 240
Query: 241 SAFLKAVQGSGDTSRHCLPTLADAKGLQDTGGTVNYFWGIPFCPDGVDPNQYTKVILCQL 300
SAFLKAVQGSGDTSRHCLPTLADAKGLQDTGGTVNYFWGIPFCPDGVDPNQYTKVILCQL
Sbjct: 241 SAFLKAVQGSGDTSRHCLPTLADAKGLQDTGGTVNYFWGIPFCPDGVDPNQYTKVILCQL 300
Query: 301 EVYQKSLKMAQRQLLNKKGFGEPVLPRPPSLIQNECGQGEQASEKNECISEDMGDEDKEE 360
EVYQKSLKMAQRQLLNKKGFGEPVLPRPPSLIQNECGQGEQASEKNECISEDMGDEDKEE
Sbjct: 301 EVYQKSLKMAQRQLLNKKGFGEPVLPRPPSLIQNECGQGEQASEKNECISEDMGDEDKEE 360
Query: 361 RQESRASDWHSKTKDFQESSIKSLKEKLLLEEEPTTSHGQSSQGIVEETSEEGNSVPASQ 420
RQESRASDWHSKTKDFQESSIKSLKEKLLLEEEPTTSHGQSSQGIVEETSEEGNSVPASQ
Sbjct: 361 RQESRASDWHSKTKDFQESSIKSLKEKLLLEEEPTTSHGQSSQGIVEETSEEGNSVPASQ 420
Query: 421 SVAALTSKRSLVLMPESSAEEITVCPETQLSSSETFDLEREVSPGSRDILDGVRIIMADK 480
SVAALTSKRSLVLMPESSAEEITVCPETQLSSSETFDLEREVSPGSRDILDGVRIIMADK
Sbjct: 421 SVAALTSKRSLVLMPESSAEEITVCPETQLSSSETFDLEREVSPGSRDILDGVRIIMADK 480
Query: 481 EVGNKEDAEKEVAISTFSSSNQVSCPLCDQCFPPTKIERHAMYCNGLMEEDTVLTRRQKE 540
EVGNKEDAEKEVAISTFSSSNQVSCPLCDQCFPPTKIERHAMYCNGLMEEDTVLTRRQKE
Sbjct: 481 EVGNKEDAEKEVAISTFSSSNQVSCPLCDQCFPPTKIERHAMYCNGLMEEDTVLTRRQKE 540
Query: 541 AKTKSDSGTAAQTSLDIDKNEKCYLCKSLVPFREYQCHVDSCLQLAKADQGDGPEGSGRA 600
AKTKSDSGTAAQTSLDIDKNEKCYLCKSLVPFREYQCHVDSCLQLAKADQGDGPEGSGRA
Sbjct: 541 AKTKSDSGTAAQTSLDIDKNEKCYLCKSLVPFREYQCHVDSCLQLAKADQGDGPEGSGRA 600
Query: 601 CSTVEGKWQQRLKNPKEKGHSEGRLLSFLEQSEHKTSDADIKSSETGAFRVPSPGMEEAG 660
CSTVEGKWQQRLKNPKEKGHSEGRLLSFLEQSEHKTSDADIKSSETGAFRVPSPGMEEAG
Sbjct: 601 CSTVEGKWQQRLKNPKEKGHSEGRLLSFLEQSEHKTSDADIKSSETGAFRVPSPGMEEAG 660
Query: 661 CSREMQSSFTRRDLNESPVKSFVSISEATDCLVDFKKQVTVQPGSRTRTKAGRGRRRKF 719
CSREMQSSFTRRDLNESPVKSFVSISEATDCLVDFKKQVTVQPGSRTRTKAGRGRRRKF
Sbjct: 661 CSREMQSSFTRRDLNESPVKSFVSISEATDCLVDFKKQVTVQPGSRTRTKAGRGRRRKF 719
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 42.4 bits (98), Expect = 0.002
Identities = 33/115 (28%), Positives = 60/115 (52%), Gaps = 13/115 (11%)
Query: 3 RRKKKVKEVSESRNLEKKDVETTSSVSVKRKRRLEDAFIVISDSDGEEPKEENGLQKTKT 62
+R++++++V ++R E + ++K+++E F I D E+ KEE L + K
Sbjct: 573 KREERLRKVLQAR-------ERVEQMKEEKKKQIEQKFAQI-DEKTEKAKEER-LAEEKA 623
Query: 63 KQSNRAKCLAKRKIAQMTEEEQFALALKMSEQEARE----VNSQEEEEEELLRKA 113
K+ AK + + + + EEE L E+E R + ++EEE+E LRKA
Sbjct: 624 KKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKA 678
Score = 39.7 bits (91), Expect = 0.010
Identities = 29/109 (26%), Positives = 52/109 (47%), Gaps = 8/109 (7%)
Query: 5 KKKVKEVSESRNLEKKDVETTSSVSVKRKRRLEDAFIVISDSDGEEPKEENGLQKTKTKQ 64
K K + ++E + +K + V +RK+ E + + EE + + LQK K ++
Sbjct: 612 KAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEE 671
Query: 65 SNRAKCLAKRK-IAQMTEEEQFALALKMSEQEAREVNSQEEEEEELLRK 112
R + A+ K +A+ E+E+ EQE RE +E+E E R+
Sbjct: 672 QERLRKAAEAKRLAEQREQER-------REQERREQERREQERREQERR 713
Score = 38.5 bits (88), Expect = 0.022
Identities = 36/150 (24%), Positives = 67/150 (44%), Gaps = 10/150 (6%)
Query: 50 EPKEENGLQKTKTKQSNRAKCL--AKRKIAQMTEEEQFALALKMSEQEAREVNSQEEE-- 105
E + L++ K K+ R + + A+ ++ QM EE++ + K ++ + + ++EE
Sbjct: 560 EEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLA 619
Query: 106 EEELLRKAIA---ESLNSCRPSDASATRSRPLATGPSSQSHQEKTTDSGLTEGIWQLVPP 162
EE+ +KA A E + + R + A R R L + HQE E Q
Sbjct: 620 EEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEE---QERLR 676
Query: 163 SLFKGSHISQGNEAEEREEPWDHTEKTEEE 192
+ +++ E E RE+ E+ E+E
Sbjct: 677 KAAEAKRLAEQREQERREQERREQERREQE 706
Score = 30.8 bits (68), Expect = 4.6
Identities = 30/108 (27%), Positives = 49/108 (45%), Gaps = 7/108 (6%)
Query: 4 RKKKVKEVSESRNLEKKDVETTSSVSVKRKRRLEDAFIVISDSDGEEPKEENGLQKTKTK 63
R+K+ E + +E+ V +KR+ RL V+ + E +E ++ + K
Sbjct: 546 RRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRK---VLQARERVEQMKEEKKKQIEQK 602
Query: 64 QSNRAKCLAKRKIAQMTEEE--QFALALKMSEQEAREVNSQEEEEEEL 109
+ + K K ++ EE+ + A A KM E EAR QEEE L
Sbjct: 603 FAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARR--KQEEEARRL 648
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 42.4 bits (98), Expect = 0.002
Identities = 33/115 (28%), Positives = 60/115 (52%), Gaps = 13/115 (11%)
Query: 3 RRKKKVKEVSESRNLEKKDVETTSSVSVKRKRRLEDAFIVISDSDGEEPKEENGLQKTKT 62
+R++++++V ++R E + ++K+++E F I D E+ KEE L + K
Sbjct: 569 KREERLRKVLQAR-------ERVEQMKEEKKKQIEQKFAQI-DEKTEKAKEER-LAEEKA 619
Query: 63 KQSNRAKCLAKRKIAQMTEEEQFALALKMSEQEARE----VNSQEEEEEELLRKA 113
K+ AK + + + + EEE L E+E R + ++EEE+E LRKA
Sbjct: 620 KKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKA 674
Score = 40.0 bits (92), Expect = 0.008
Identities = 43/183 (23%), Positives = 80/183 (43%), Gaps = 15/183 (8%)
Query: 17 LEKKDVETTSSVSVKRKRRLEDAFIVISDSDGEEPKEENGLQKTKTKQSNRAKCL--AKR 74
++ K+ E +++RK E + EE K L++ K K+ R + + A+
Sbjct: 528 MDPKEKERQRLENLRRKEEAEQ----LRRQKVEEDKRRR-LEEVKLKREERLRKVLQARE 582
Query: 75 KIAQMTEEEQFALALKMSEQEAREVNSQEEE--EEELLRKAIA---ESLNSCRPSDASAT 129
++ QM EE++ + K ++ + + ++EE EE+ +KA A E + + R + A
Sbjct: 583 RVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEAR 642
Query: 130 RSRPLATGPSSQSHQEKTTDSGLTEGIWQLVPPSLFKGSHISQGNEAEEREEPWDHTEKT 189
R R L + HQE E Q + +++ E E RE+ E+
Sbjct: 643 RLRWLQQEEEERRHQELLQKKKEEE---QERLRKAAEAKRLAEQREQERREQERREQERR 699
Query: 190 EEE 192
E+E
Sbjct: 700 EQE 702
Score = 39.7 bits (91), Expect = 0.010
Identities = 29/109 (26%), Positives = 52/109 (47%), Gaps = 8/109 (7%)
Query: 5 KKKVKEVSESRNLEKKDVETTSSVSVKRKRRLEDAFIVISDSDGEEPKEENGLQKTKTKQ 64
K K + ++E + +K + V +RK+ E + + EE + + LQK K ++
Sbjct: 608 KAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEE 667
Query: 65 SNRAKCLAKRK-IAQMTEEEQFALALKMSEQEAREVNSQEEEEEELLRK 112
R + A+ K +A+ E+E+ EQE RE +E+E E R+
Sbjct: 668 QERLRKAAEAKRLAEQREQER-------REQERREQERREQERREQERR 709
Score = 30.8 bits (68), Expect = 4.6
Identities = 30/108 (27%), Positives = 49/108 (45%), Gaps = 7/108 (6%)
Query: 4 RKKKVKEVSESRNLEKKDVETTSSVSVKRKRRLEDAFIVISDSDGEEPKEENGLQKTKTK 63
R+K+ E + +E+ V +KR+ RL V+ + E +E ++ + K
Sbjct: 542 RRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRK---VLQARERVEQMKEEKKKQIEQK 598
Query: 64 QSNRAKCLAKRKIAQMTEEE--QFALALKMSEQEAREVNSQEEEEEEL 109
+ + K K ++ EE+ + A A KM E EAR QEEE L
Sbjct: 599 FAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARR--KQEEEARRL 644
>gi|219842214 protein phosphatase 1, regulatory (inhibitor) subunit
12A isoform b [Homo sapiens]
Length = 943
Score = 42.0 bits (97), Expect = 0.002
Identities = 61/278 (21%), Positives = 102/278 (36%), Gaps = 35/278 (12%)
Query: 8 VKEVSESRNLEKKDVETTSSVSVKRKRRLEDAFIVISDSDGEEPKEENGLQKTKTKQSNR 67
V + + L T SS + R+RR + D + E ++ Q ++++S +
Sbjct: 552 VNAAASTTTLTTTTAGTVSSTTEVRERR-RSYLTPVRDEESESQRKARSRQARQSRRSTQ 610
Query: 68 AKCLAKRKIAQMT--------EEEQFALALKMSEQEAREVNSQEEEEEELLRKAIAESLN 119
L + A+ T EQ + E+E ++ QEE++E +
Sbjct: 611 GVTLTDLQEAEKTIGRSRSTRTREQENEEKEKEEKEKQDKEKQEEKKESETSREDEYKQK 670
Query: 120 SCRPSDASATRSRPLATGPSSQSHQEKTTDSGLTEGIWQLVPPSLFKG--SHISQG---- 173
R D + R RP++T S+ +T S QL P+ G S S+G
Sbjct: 671 YSRTYDETYQRYRPVSTSSSTTPSSSLSTMSSSLYASSQLNRPNSLVGITSAYSRGITKE 730
Query: 174 --NEAEEREEPWDHTEKTEEEPV-----------SGSSGSWDQSSQPVFENVNVKSFDRC 220
E E+REE + +K++ + + S W Q S EN + D
Sbjct: 731 NEREGEKREEEKEGEDKSQPKSIRERRRPREKRRSTGVSFWTQDSD---ENEQEQQSDTE 787
Query: 221 TGHSAEHTQCGK----PQESTGRGSAFLKAVQGSGDTS 254
G + + TQ ST G + + SG S
Sbjct: 788 EGSNKKETQTDSISRYETSSTSAGDRYDSLLGRSGSYS 825
>gi|219842212 protein phosphatase 1, regulatory (inhibitor) subunit
12A isoform a [Homo sapiens]
Length = 1030
Score = 42.0 bits (97), Expect = 0.002
Identities = 61/278 (21%), Positives = 102/278 (36%), Gaps = 35/278 (12%)
Query: 8 VKEVSESRNLEKKDVETTSSVSVKRKRRLEDAFIVISDSDGEEPKEENGLQKTKTKQSNR 67
V + + L T SS + R+RR + D + E ++ Q ++++S +
Sbjct: 639 VNAAASTTTLTTTTAGTVSSTTEVRERR-RSYLTPVRDEESESQRKARSRQARQSRRSTQ 697
Query: 68 AKCLAKRKIAQMT--------EEEQFALALKMSEQEAREVNSQEEEEEELLRKAIAESLN 119
L + A+ T EQ + E+E ++ QEE++E +
Sbjct: 698 GVTLTDLQEAEKTIGRSRSTRTREQENEEKEKEEKEKQDKEKQEEKKESETSREDEYKQK 757
Query: 120 SCRPSDASATRSRPLATGPSSQSHQEKTTDSGLTEGIWQLVPPSLFKG--SHISQG---- 173
R D + R RP++T S+ +T S QL P+ G S S+G
Sbjct: 758 YSRTYDETYQRYRPVSTSSSTTPSSSLSTMSSSLYASSQLNRPNSLVGITSAYSRGITKE 817
Query: 174 --NEAEEREEPWDHTEKTEEEPV-----------SGSSGSWDQSSQPVFENVNVKSFDRC 220
E E+REE + +K++ + + S W Q S EN + D
Sbjct: 818 NEREGEKREEEKEGEDKSQPKSIRERRRPREKRRSTGVSFWTQDSD---ENEQEQQSDTE 874
Query: 221 TGHSAEHTQCGK----PQESTGRGSAFLKAVQGSGDTS 254
G + + TQ ST G + + SG S
Sbjct: 875 EGSNKKETQTDSISRYETSSTSAGDRYDSLLGRSGSYS 912
>gi|4505317 protein phosphatase 1, regulatory (inhibitor) subunit
12A isoform a [Homo sapiens]
Length = 1030
Score = 42.0 bits (97), Expect = 0.002
Identities = 61/278 (21%), Positives = 102/278 (36%), Gaps = 35/278 (12%)
Query: 8 VKEVSESRNLEKKDVETTSSVSVKRKRRLEDAFIVISDSDGEEPKEENGLQKTKTKQSNR 67
V + + L T SS + R+RR + D + E ++ Q ++++S +
Sbjct: 639 VNAAASTTTLTTTTAGTVSSTTEVRERR-RSYLTPVRDEESESQRKARSRQARQSRRSTQ 697
Query: 68 AKCLAKRKIAQMT--------EEEQFALALKMSEQEAREVNSQEEEEEELLRKAIAESLN 119
L + A+ T EQ + E+E ++ QEE++E +
Sbjct: 698 GVTLTDLQEAEKTIGRSRSTRTREQENEEKEKEEKEKQDKEKQEEKKESETSREDEYKQK 757
Query: 120 SCRPSDASATRSRPLATGPSSQSHQEKTTDSGLTEGIWQLVPPSLFKG--SHISQG---- 173
R D + R RP++T S+ +T S QL P+ G S S+G
Sbjct: 758 YSRTYDETYQRYRPVSTSSSTTPSSSLSTMSSSLYASSQLNRPNSLVGITSAYSRGITKE 817
Query: 174 --NEAEEREEPWDHTEKTEEEPV-----------SGSSGSWDQSSQPVFENVNVKSFDRC 220
E E+REE + +K++ + + S W Q S EN + D
Sbjct: 818 NEREGEKREEEKEGEDKSQPKSIRERRRPREKRRSTGVSFWTQDSD---ENEQEQQSDTE 874
Query: 221 TGHSAEHTQCGK----PQESTGRGSAFLKAVQGSGDTS 254
G + + TQ ST G + + SG S
Sbjct: 875 EGSNKKETQTDSISRYETSSTSAGDRYDSLLGRSGSYS 912
>gi|74136549 AT rich interactive domain 5B (MRF1-like) [Homo
sapiens]
Length = 1188
Score = 42.0 bits (97), Expect = 0.002
Identities = 29/104 (27%), Positives = 50/104 (48%), Gaps = 8/104 (7%)
Query: 340 EQASEKNECISEDMGDEDKEERQESRASDWHSKTKDFQESSIKSLKEKLLLEEEPTTSHG 399
EQ E+ IS+ K + A+D K + +QE S K L ++ E++ T G
Sbjct: 470 EQEKEQETLISQ------KSIPEPLPAADMKKKIEGYQEFSAKPLASRVDPEKDNETDQG 523
Query: 400 QSSQGIVEETSEEGNSVPASQSVAALTSKRSLVLMPESSAEEIT 443
+S+ + EE E+G + P A L ++ L+P +S + +T
Sbjct: 524 SNSEKVAEEAGEKGPTPPLPS--APLAPEKDSALVPGASKQPLT 565
Score = 31.6 bits (70), Expect = 2.7
Identities = 22/69 (31%), Positives = 38/69 (55%), Gaps = 6/69 (8%)
Query: 52 KEENGLQKTKTKQSNRAKCLAKRKIAQMTEEEQFALALKMSEQEAREVNSQEEEEEELL- 110
K+EN Q+ + K K +I + +E++ A Q+A EV+S++E+E+E L
Sbjct: 424 KQENSSQENENKTKVSGTKRIKHEIPKSKKEKENA----PKPQDAAEVSSEQEKEQETLI 479
Query: 111 -RKAIAESL 118
+K+I E L
Sbjct: 480 SQKSIPEPL 488
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 41.2 bits (95), Expect = 0.003
Identities = 31/106 (29%), Positives = 48/106 (45%), Gaps = 21/106 (19%)
Query: 3 RRKKKVKEVSESRNLEKKDVETTSSVSVKRKRRLEDAFIVISDSDGEEPKEENGLQKTKT 62
++KKK KE E+ E+ + E K KR+ E+ KE+ +KTK
Sbjct: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRK-------------EKRKEKEKKKKTKE 48
Query: 63 KQSNRAKCLAKRKIAQMTEEEQFALALKMSEQEAREVNSQEEEEEE 108
+ KRK + E+++ K E+E RE +EEEEE+
Sbjct: 49 TE--------KRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEK 86
Score = 37.4 bits (85), Expect = 0.049
Identities = 30/110 (27%), Positives = 50/110 (45%), Gaps = 16/110 (14%)
Query: 3 RRKKKVKEVSESRNLEKKDVETTSSVSVKRKRRLEDAFIVISDSDGEEPKEENGLQKTKT 62
++KKK E +E +++ E KRK + ++ E+ K+ +K K
Sbjct: 4 KKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEK---------EKKKKTKETEKRKE 54
Query: 63 KQSNRAKCLAKRKIAQMTEEEQFALALKMSEQEAREVNSQEEEEEELLRK 112
K+ K KRK + EEE+ + E+E E +EEE+EE R+
Sbjct: 55 KEEEEKK--RKRKRKKKKEEEE-----REEEEEEEEEEKEEEEKEEGRRR 97
>gi|21735569 claspin [Homo sapiens]
Length = 1339
Score = 40.0 bits (92), Expect = 0.008
Identities = 55/253 (21%), Positives = 94/253 (37%), Gaps = 36/253 (14%)
Query: 6 KKVKEVSESRNLEKKDVETTSSVSVKRKRRLED-----AFIVISDSDGEEPKEENGLQKT 60
KK+ S ++ EK V + RR E+ A + + DG E +EE + T
Sbjct: 580 KKLDGASHTKPGEKLQVLKAKLQEAMKLRRFEERQKRQALFKLDNEDGFEEEEEEEEEMT 639
Query: 61 KTKQSNRAKCLAKRKIAQMTEEEQFALALKMSEQEAREVNSQEEEEEELLRKAIAESLNS 120
+ + + + K + E+E E +EEEEEE + AE L S
Sbjct: 640 DESEEDGEEKVEKEE----------------KEEELEEEEEKEEEEEEEGNQETAEFLLS 683
Query: 121 CRPSDASATRSRPLATGPSSQSHQEKTTDSGLTEGIWQLVPPSLFKGSHISQGNEAEERE 180
+ + + + + +++ G G VP SL S + ++ +
Sbjct: 684 SEEIETKDEKE-------MDKENNDGSSEIGKAVGFLS-VPKSLSSDSTLLLFKDSSSKM 735
Query: 181 EPWDHTEKTEEEPVSGSSGSW----DQSSQPVFENVNVKSFDRCTGHSAEHTQCGKPQES 236
+ EK+E + SG S D S E+ + SF+ + C +
Sbjct: 736 GYFPTEEKSETDENSGKQPSKLDEDDSCSLLTKESSHNSSFELIGSTIPSYQPCNR---Q 792
Query: 237 TGRGSAFLKAVQG 249
TGRG++F G
Sbjct: 793 TGRGTSFFPTAGG 805
Score = 34.7 bits (78), Expect = 0.32
Identities = 40/159 (25%), Positives = 70/159 (44%), Gaps = 21/159 (13%)
Query: 289 PNQYTKVILCQLEVYQKSLKMAQRQ-------LLNKKGFGEPVLPRPPSLIQNECGQGEQ 341
P + +V+ +L+ K + +RQ L N+ GF E ++E GE+
Sbjct: 590 PGEKLQVLKAKLQEAMKLRRFEERQKRQALFKLDNEDGFEEEEEEEEEMTDESE-EDGEE 648
Query: 342 ASEKNECISEDMGDEDKEERQESRASDWHSKTKDFQESSIKSLKEKLLLEEEPTTSHGQS 401
EK E E +E+KEE +E + + +T +F SS EE T +
Sbjct: 649 KVEKEEKEEELEEEEEKEEEEE---EEGNQETAEFLLSS----------EEIETKDEKEM 695
Query: 402 SQGIVEETSEEGNSVPASQSVAALTSKRSLVLMPESSAE 440
+ + +SE G +V +L+S +L+L +SS++
Sbjct: 696 DKENNDGSSEIGKAVGFLSVPKSLSSDSTLLLFKDSSSK 734
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 40.0 bits (92), Expect = 0.008
Identities = 53/182 (29%), Positives = 77/182 (42%), Gaps = 38/182 (20%)
Query: 326 PRPPSLIQNECGQG-----EQASEKNECISEDMGDEDKEERQESRASDWHSKTKDFQESS 380
PRPP + E G G E+ E+ + +S D+ D ER+ S A +++ E
Sbjct: 224 PRPPRE-RFELGDGRKPVKEEKMEERDLLS-DLQDISDSERKTSSAESSSAESGSGSEEE 281
Query: 381 IKSLKEKLLLEEEPTTSHGQSSQGIVEETSEEGNSVPASQSVAALTSKRSLVLMPESSAE 440
+ +E+ EEE +TS + EE EE S S A E SAE
Sbjct: 282 EEEEEEE---EEEGSTSEESEEE---EEEEEEEEEETGSNSEEA----------SEQSAE 325
Query: 441 EITVCPETQLSSSETFDLERE--VSPGSRDILDGVRIIMADKEVGNKEDAEKEVAISTFS 498
E++ E ++S E + E V P SR D++ G E+AE+EV T
Sbjct: 326 EVS---EEEMSEDEERENENHLLVVPESR----------FDRDSGESEEAEEEVGEGTPQ 372
Query: 499 SS 500
SS
Sbjct: 373 SS 374
Score = 36.6 bits (83), Expect = 0.083
Identities = 52/256 (20%), Positives = 100/256 (39%), Gaps = 54/256 (21%)
Query: 3 RRKKKVKEVSESRNLEKK--DVETTSSVSVKRKRRLEDAFIVISDSDGEEPKEENGLQKT 60
R + +++++ R E+K + + +R+RR E+ + E +E + +T
Sbjct: 151 RERDRLEQLERKRERERKMREQQKEQREQKERERRAEER-----RKEREARREVSAHHRT 205
Query: 61 KTKQ-SNRAKCLAKRKIAQMTEEEQFALALKMSEQEAREVNSQEEEEEELLRKAIAESLN 119
+ S++ K + E+F L + R+ +E+ EE L + + +
Sbjct: 206 MREDYSDKVKASHWSRSPPRPPRERFELG------DGRKPVKEEKMEERDLLSDLQDISD 259
Query: 120 SCRPSDASATRSRPLATGPSSQSHQEKTTDSGLTEGIWQLVPPSLFKGSHISQGNEAEER 179
S R + ++ + S +G + +E+ + +G+ +EE
Sbjct: 260 SERKTSSAESSSAESGSGSEEEEEEEEEEEE---------------------EGSTSEES 298
Query: 180 EEPWDHTEKTEEEPVSGSSGSWDQSSQPVFEN----------------VNVKSFDRCTGH 223
EE + E+ EEE S S + +QS++ V E V FDR +G
Sbjct: 299 EEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGE 358
Query: 224 SAEHTQ---CGKPQES 236
S E + G PQ S
Sbjct: 359 SEEAEEEVGEGTPQSS 374
Score = 32.3 bits (72), Expect = 1.6
Identities = 24/104 (23%), Positives = 43/104 (41%), Gaps = 16/104 (15%)
Query: 335 ECGQGEQASEKNECISEDMGD-----EDKEERQESRASDWHSKTKDFQESSIKSLKEKLL 389
E G G + E+ E E+ G E++EE +E + S +++ E S + + E+ +
Sbjct: 273 ESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEM 332
Query: 390 LEEE-----------PTTSHGQSSQGIVEETSEEGNSVPASQSV 422
E+E P + + S E E G P S ++
Sbjct: 333 SEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSAL 376
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 40.0 bits (92), Expect = 0.008
Identities = 53/182 (29%), Positives = 77/182 (42%), Gaps = 38/182 (20%)
Query: 326 PRPPSLIQNECGQG-----EQASEKNECISEDMGDEDKEERQESRASDWHSKTKDFQESS 380
PRPP + E G G E+ E+ + +S D+ D ER+ S A +++ E
Sbjct: 234 PRPPRE-RFELGDGRKPVKEEKMEERDLLS-DLQDISDSERKTSSAESSSAESGSGSEEE 291
Query: 381 IKSLKEKLLLEEEPTTSHGQSSQGIVEETSEEGNSVPASQSVAALTSKRSLVLMPESSAE 440
+ +E+ EEE +TS + EE EE S S A E SAE
Sbjct: 292 EEEEEEE---EEEGSTSEESEEE---EEEEEEEEEETGSNSEEA----------SEQSAE 335
Query: 441 EITVCPETQLSSSETFDLERE--VSPGSRDILDGVRIIMADKEVGNKEDAEKEVAISTFS 498
E++ E ++S E + E V P SR D++ G E+AE+EV T
Sbjct: 336 EVS---EEEMSEDEERENENHLLVVPESR----------FDRDSGESEEAEEEVGEGTPQ 382
Query: 499 SS 500
SS
Sbjct: 383 SS 384
Score = 36.6 bits (83), Expect = 0.083
Identities = 52/256 (20%), Positives = 100/256 (39%), Gaps = 54/256 (21%)
Query: 3 RRKKKVKEVSESRNLEKK--DVETTSSVSVKRKRRLEDAFIVISDSDGEEPKEENGLQKT 60
R + +++++ R E+K + + +R+RR E+ + E +E + +T
Sbjct: 161 RERDRLEQLERKRERERKMREQQKEQREQKERERRAEER-----RKEREARREVSAHHRT 215
Query: 61 KTKQ-SNRAKCLAKRKIAQMTEEEQFALALKMSEQEAREVNSQEEEEEELLRKAIAESLN 119
+ S++ K + E+F L + R+ +E+ EE L + + +
Sbjct: 216 MREDYSDKVKASHWSRSPPRPPRERFELG------DGRKPVKEEKMEERDLLSDLQDISD 269
Query: 120 SCRPSDASATRSRPLATGPSSQSHQEKTTDSGLTEGIWQLVPPSLFKGSHISQGNEAEER 179
S R + ++ + S +G + +E+ + +G+ +EE
Sbjct: 270 SERKTSSAESSSAESGSGSEEEEEEEEEEEE---------------------EGSTSEES 308
Query: 180 EEPWDHTEKTEEEPVSGSSGSWDQSSQPVFEN----------------VNVKSFDRCTGH 223
EE + E+ EEE S S + +QS++ V E V FDR +G
Sbjct: 309 EEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGE 368
Query: 224 SAEHTQ---CGKPQES 236
S E + G PQ S
Sbjct: 369 SEEAEEEVGEGTPQSS 384
Score = 32.3 bits (72), Expect = 1.6
Identities = 24/104 (23%), Positives = 43/104 (41%), Gaps = 16/104 (15%)
Query: 335 ECGQGEQASEKNECISEDMGD-----EDKEERQESRASDWHSKTKDFQESSIKSLKEKLL 389
E G G + E+ E E+ G E++EE +E + S +++ E S + + E+ +
Sbjct: 283 ESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEM 342
Query: 390 LEEE-----------PTTSHGQSSQGIVEETSEEGNSVPASQSV 422
E+E P + + S E E G P S ++
Sbjct: 343 SEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSAL 386
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 40.0 bits (92), Expect = 0.008
Identities = 53/182 (29%), Positives = 77/182 (42%), Gaps = 38/182 (20%)
Query: 326 PRPPSLIQNECGQG-----EQASEKNECISEDMGDEDKEERQESRASDWHSKTKDFQESS 380
PRPP + E G G E+ E+ + +S D+ D ER+ S A +++ E
Sbjct: 225 PRPPRE-RFELGDGRKPVKEEKMEERDLLS-DLQDISDSERKTSSAESSSAESGSGSEEE 282
Query: 381 IKSLKEKLLLEEEPTTSHGQSSQGIVEETSEEGNSVPASQSVAALTSKRSLVLMPESSAE 440
+ +E+ EEE +TS + EE EE S S A E SAE
Sbjct: 283 EEEEEEE---EEEGSTSEESEEE---EEEEEEEEEETGSNSEEA----------SEQSAE 326
Query: 441 EITVCPETQLSSSETFDLERE--VSPGSRDILDGVRIIMADKEVGNKEDAEKEVAISTFS 498
E++ E ++S E + E V P SR D++ G E+AE+EV T
Sbjct: 327 EVS---EEEMSEDEERENENHLLVVPESR----------FDRDSGESEEAEEEVGEGTPQ 373
Query: 499 SS 500
SS
Sbjct: 374 SS 375
Score = 36.6 bits (83), Expect = 0.083
Identities = 52/256 (20%), Positives = 100/256 (39%), Gaps = 54/256 (21%)
Query: 3 RRKKKVKEVSESRNLEKK--DVETTSSVSVKRKRRLEDAFIVISDSDGEEPKEENGLQKT 60
R + +++++ R E+K + + +R+RR E+ + E +E + +T
Sbjct: 152 RERDRLEQLERKRERERKMREQQKEQREQKERERRAEER-----RKEREARREVSAHHRT 206
Query: 61 KTKQ-SNRAKCLAKRKIAQMTEEEQFALALKMSEQEAREVNSQEEEEEELLRKAIAESLN 119
+ S++ K + E+F L + R+ +E+ EE L + + +
Sbjct: 207 MREDYSDKVKASHWSRSPPRPPRERFELG------DGRKPVKEEKMEERDLLSDLQDISD 260
Query: 120 SCRPSDASATRSRPLATGPSSQSHQEKTTDSGLTEGIWQLVPPSLFKGSHISQGNEAEER 179
S R + ++ + S +G + +E+ + +G+ +EE
Sbjct: 261 SERKTSSAESSSAESGSGSEEEEEEEEEEEE---------------------EGSTSEES 299
Query: 180 EEPWDHTEKTEEEPVSGSSGSWDQSSQPVFEN----------------VNVKSFDRCTGH 223
EE + E+ EEE S S + +QS++ V E V FDR +G
Sbjct: 300 EEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGE 359
Query: 224 SAEHTQ---CGKPQES 236
S E + G PQ S
Sbjct: 360 SEEAEEEVGEGTPQSS 375
Score = 32.3 bits (72), Expect = 1.6
Identities = 24/104 (23%), Positives = 43/104 (41%), Gaps = 16/104 (15%)
Query: 335 ECGQGEQASEKNECISEDMGD-----EDKEERQESRASDWHSKTKDFQESSIKSLKEKLL 389
E G G + E+ E E+ G E++EE +E + S +++ E S + + E+ +
Sbjct: 274 ESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEM 333
Query: 390 LEEE-----------PTTSHGQSSQGIVEETSEEGNSVPASQSV 422
E+E P + + S E E G P S ++
Sbjct: 334 SEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSAL 377
>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
8 [Homo sapiens]
Length = 780
Score = 40.0 bits (92), Expect = 0.008
Identities = 53/182 (29%), Positives = 77/182 (42%), Gaps = 38/182 (20%)
Query: 326 PRPPSLIQNECGQG-----EQASEKNECISEDMGDEDKEERQESRASDWHSKTKDFQESS 380
PRPP + E G G E+ E+ + +S D+ D ER+ S A +++ E
Sbjct: 234 PRPPRE-RFELGDGRKPVKEEKMEERDLLS-DLQDISDSERKTSSAESSSAESGSGSEEE 291
Query: 381 IKSLKEKLLLEEEPTTSHGQSSQGIVEETSEEGNSVPASQSVAALTSKRSLVLMPESSAE 440
+ +E+ EEE +TS + EE EE S S A E SAE
Sbjct: 292 EEEEEEE---EEEGSTSEESEEE---EEEEEEEEEETGSNSEEA----------SEQSAE 335
Query: 441 EITVCPETQLSSSETFDLERE--VSPGSRDILDGVRIIMADKEVGNKEDAEKEVAISTFS 498
E++ E ++S E + E V P SR D++ G E+AE+EV T
Sbjct: 336 EVS---EEEMSEDEERENENHLLVVPESR----------FDRDSGESEEAEEEVGEGTPQ 382
Query: 499 SS 500
SS
Sbjct: 383 SS 384
Score = 36.6 bits (83), Expect = 0.083
Identities = 57/293 (19%), Positives = 108/293 (36%), Gaps = 61/293 (20%)
Query: 4 RKKKVKEVSESRNLEKKD--VETTSSVSVKRKRRLEDAFIVISDSDGEEPKEENGLQKTK 61
RK+KV + + EKK V+ +RKR E+ + + ++ + E + ++
Sbjct: 93 RKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQK-RREMAREHSR 151
Query: 62 TKQSNRAKCLAKRKIAQMTEEEQFALALK-----MSEQEAREVNSQEEEEEELLRKAIAE 116
++ N CL + ++ Q+ + + ++ EQ+ RE ++E +E R+ ++
Sbjct: 152 RERGNDGVCLFRDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSA 211
Query: 117 SLNSCRPSDASATRSRPLATGPSSQSHQ-------------EKTTDSGLTEGIWQLVPPS 163
+ R + ++ + P + EK + L + +
Sbjct: 212 HHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSE 271
Query: 164 LFKGSHIS---------------------QGNEAEEREEPWDHTEKTEEEPVSGSSGSWD 202
S S +G+ +EE EE + E+ EEE S S + +
Sbjct: 272 RKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASE 331
Query: 203 QSSQPVFEN----------------VNVKSFDRCTGHSAEHTQ---CGKPQES 236
QS++ V E V FDR +G S E + G PQ S
Sbjct: 332 QSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSS 384
Score = 32.3 bits (72), Expect = 1.6
Identities = 24/104 (23%), Positives = 43/104 (41%), Gaps = 16/104 (15%)
Query: 335 ECGQGEQASEKNECISEDMGD-----EDKEERQESRASDWHSKTKDFQESSIKSLKEKLL 389
E G G + E+ E E+ G E++EE +E + S +++ E S + + E+ +
Sbjct: 283 ESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEM 342
Query: 390 LEEE-----------PTTSHGQSSQGIVEETSEEGNSVPASQSV 422
E+E P + + S E E G P S ++
Sbjct: 343 SEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSAL 386
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
5 [Homo sapiens]
Length = 748
Score = 40.0 bits (92), Expect = 0.008
Identities = 53/182 (29%), Positives = 77/182 (42%), Gaps = 38/182 (20%)
Query: 326 PRPPSLIQNECGQG-----EQASEKNECISEDMGDEDKEERQESRASDWHSKTKDFQESS 380
PRPP + E G G E+ E+ + +S D+ D ER+ S A +++ E
Sbjct: 202 PRPPRE-RFELGDGRKPVKEEKMEERDLLS-DLQDISDSERKTSSAESSSAESGSGSEEE 259
Query: 381 IKSLKEKLLLEEEPTTSHGQSSQGIVEETSEEGNSVPASQSVAALTSKRSLVLMPESSAE 440
+ +E+ EEE +TS + EE EE S S A E SAE
Sbjct: 260 EEEEEEE---EEEGSTSEESEEE---EEEEEEEEEETGSNSEEA----------SEQSAE 303
Query: 441 EITVCPETQLSSSETFDLERE--VSPGSRDILDGVRIIMADKEVGNKEDAEKEVAISTFS 498
E++ E ++S E + E V P SR D++ G E+AE+EV T
Sbjct: 304 EVS---EEEMSEDEERENENHLLVVPESR----------FDRDSGESEEAEEEVGEGTPQ 350
Query: 499 SS 500
SS
Sbjct: 351 SS 352
Score = 36.6 bits (83), Expect = 0.083
Identities = 52/256 (20%), Positives = 100/256 (39%), Gaps = 54/256 (21%)
Query: 3 RRKKKVKEVSESRNLEKK--DVETTSSVSVKRKRRLEDAFIVISDSDGEEPKEENGLQKT 60
R + +++++ R E+K + + +R+RR E+ + E +E + +T
Sbjct: 129 RERDRLEQLERKRERERKMREQQKEQREQKERERRAEER-----RKEREARREVSAHHRT 183
Query: 61 KTKQ-SNRAKCLAKRKIAQMTEEEQFALALKMSEQEAREVNSQEEEEEELLRKAIAESLN 119
+ S++ K + E+F L + R+ +E+ EE L + + +
Sbjct: 184 MREDYSDKVKASHWSRSPPRPPRERFELG------DGRKPVKEEKMEERDLLSDLQDISD 237
Query: 120 SCRPSDASATRSRPLATGPSSQSHQEKTTDSGLTEGIWQLVPPSLFKGSHISQGNEAEER 179
S R + ++ + S +G + +E+ + +G+ +EE
Sbjct: 238 SERKTSSAESSSAESGSGSEEEEEEEEEEEE---------------------EGSTSEES 276
Query: 180 EEPWDHTEKTEEEPVSGSSGSWDQSSQPVFEN----------------VNVKSFDRCTGH 223
EE + E+ EEE S S + +QS++ V E V FDR +G
Sbjct: 277 EEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGE 336
Query: 224 SAEHTQ---CGKPQES 236
S E + G PQ S
Sbjct: 337 SEEAEEEVGEGTPQSS 352
Score = 32.3 bits (72), Expect = 1.6
Identities = 24/104 (23%), Positives = 43/104 (41%), Gaps = 16/104 (15%)
Query: 335 ECGQGEQASEKNECISEDMGD-----EDKEERQESRASDWHSKTKDFQESSIKSLKEKLL 389
E G G + E+ E E+ G E++EE +E + S +++ E S + + E+ +
Sbjct: 251 ESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEM 310
Query: 390 LEEE-----------PTTSHGQSSQGIVEETSEEGNSVPASQSV 422
E+E P + + S E E G P S ++
Sbjct: 311 SEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSAL 354
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 40.0 bits (92), Expect = 0.008
Identities = 53/182 (29%), Positives = 77/182 (42%), Gaps = 38/182 (20%)
Query: 326 PRPPSLIQNECGQG-----EQASEKNECISEDMGDEDKEERQESRASDWHSKTKDFQESS 380
PRPP + E G G E+ E+ + +S D+ D ER+ S A +++ E
Sbjct: 191 PRPPRE-RFELGDGRKPVKEEKMEERDLLS-DLQDISDSERKTSSAESSSAESGSGSEEE 248
Query: 381 IKSLKEKLLLEEEPTTSHGQSSQGIVEETSEEGNSVPASQSVAALTSKRSLVLMPESSAE 440
+ +E+ EEE +TS + EE EE S S A E SAE
Sbjct: 249 EEEEEEE---EEEGSTSEESEEE---EEEEEEEEEETGSNSEEA----------SEQSAE 292
Query: 441 EITVCPETQLSSSETFDLERE--VSPGSRDILDGVRIIMADKEVGNKEDAEKEVAISTFS 498
E++ E ++S E + E V P SR D++ G E+AE+EV T
Sbjct: 293 EVS---EEEMSEDEERENENHLLVVPESR----------FDRDSGESEEAEEEVGEGTPQ 339
Query: 499 SS 500
SS
Sbjct: 340 SS 341
Score = 36.6 bits (83), Expect = 0.083
Identities = 52/256 (20%), Positives = 100/256 (39%), Gaps = 54/256 (21%)
Query: 3 RRKKKVKEVSESRNLEKK--DVETTSSVSVKRKRRLEDAFIVISDSDGEEPKEENGLQKT 60
R + +++++ R E+K + + +R+RR E+ + E +E + +T
Sbjct: 118 RERDRLEQLERKRERERKMREQQKEQREQKERERRAEER-----RKEREARREVSAHHRT 172
Query: 61 KTKQ-SNRAKCLAKRKIAQMTEEEQFALALKMSEQEAREVNSQEEEEEELLRKAIAESLN 119
+ S++ K + E+F L + R+ +E+ EE L + + +
Sbjct: 173 MREDYSDKVKASHWSRSPPRPPRERFELG------DGRKPVKEEKMEERDLLSDLQDISD 226
Query: 120 SCRPSDASATRSRPLATGPSSQSHQEKTTDSGLTEGIWQLVPPSLFKGSHISQGNEAEER 179
S R + ++ + S +G + +E+ + +G+ +EE
Sbjct: 227 SERKTSSAESSSAESGSGSEEEEEEEEEEEE---------------------EGSTSEES 265
Query: 180 EEPWDHTEKTEEEPVSGSSGSWDQSSQPVFEN----------------VNVKSFDRCTGH 223
EE + E+ EEE S S + +QS++ V E V FDR +G
Sbjct: 266 EEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGE 325
Query: 224 SAEHTQ---CGKPQES 236
S E + G PQ S
Sbjct: 326 SEEAEEEVGEGTPQSS 341
Score = 32.3 bits (72), Expect = 1.6
Identities = 24/104 (23%), Positives = 43/104 (41%), Gaps = 16/104 (15%)
Query: 335 ECGQGEQASEKNECISEDMGD-----EDKEERQESRASDWHSKTKDFQESSIKSLKEKLL 389
E G G + E+ E E+ G E++EE +E + S +++ E S + + E+ +
Sbjct: 240 ESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEM 299
Query: 390 LEEE-----------PTTSHGQSSQGIVEETSEEGNSVPASQSV 422
E+E P + + S E E G P S ++
Sbjct: 300 SEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSAL 343
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
2 [Homo sapiens]
Length = 782
Score = 40.0 bits (92), Expect = 0.008
Identities = 53/182 (29%), Positives = 77/182 (42%), Gaps = 38/182 (20%)
Query: 326 PRPPSLIQNECGQG-----EQASEKNECISEDMGDEDKEERQESRASDWHSKTKDFQESS 380
PRPP + E G G E+ E+ + +S D+ D ER+ S A +++ E
Sbjct: 236 PRPPRE-RFELGDGRKPVKEEKMEERDLLS-DLQDISDSERKTSSAESSSAESGSGSEEE 293
Query: 381 IKSLKEKLLLEEEPTTSHGQSSQGIVEETSEEGNSVPASQSVAALTSKRSLVLMPESSAE 440
+ +E+ EEE +TS + EE EE S S A E SAE
Sbjct: 294 EEEEEEE---EEEGSTSEESEEE---EEEEEEEEEETGSNSEEA----------SEQSAE 337
Query: 441 EITVCPETQLSSSETFDLERE--VSPGSRDILDGVRIIMADKEVGNKEDAEKEVAISTFS 498
E++ E ++S E + E V P SR D++ G E+AE+EV T
Sbjct: 338 EVS---EEEMSEDEERENENHLLVVPESR----------FDRDSGESEEAEEEVGEGTPQ 384
Query: 499 SS 500
SS
Sbjct: 385 SS 386
Score = 36.6 bits (83), Expect = 0.083
Identities = 52/256 (20%), Positives = 100/256 (39%), Gaps = 54/256 (21%)
Query: 3 RRKKKVKEVSESRNLEKK--DVETTSSVSVKRKRRLEDAFIVISDSDGEEPKEENGLQKT 60
R + +++++ R E+K + + +R+RR E+ + E +E + +T
Sbjct: 163 RERDRLEQLERKRERERKMREQQKEQREQKERERRAEER-----RKEREARREVSAHHRT 217
Query: 61 KTKQ-SNRAKCLAKRKIAQMTEEEQFALALKMSEQEAREVNSQEEEEEELLRKAIAESLN 119
+ S++ K + E+F L + R+ +E+ EE L + + +
Sbjct: 218 MREDYSDKVKASHWSRSPPRPPRERFELG------DGRKPVKEEKMEERDLLSDLQDISD 271
Query: 120 SCRPSDASATRSRPLATGPSSQSHQEKTTDSGLTEGIWQLVPPSLFKGSHISQGNEAEER 179
S R + ++ + S +G + +E+ + +G+ +EE
Sbjct: 272 SERKTSSAESSSAESGSGSEEEEEEEEEEEE---------------------EGSTSEES 310
Query: 180 EEPWDHTEKTEEEPVSGSSGSWDQSSQPVFEN----------------VNVKSFDRCTGH 223
EE + E+ EEE S S + +QS++ V E V FDR +G
Sbjct: 311 EEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGE 370
Query: 224 SAEHTQ---CGKPQES 236
S E + G PQ S
Sbjct: 371 SEEAEEEVGEGTPQSS 386
Score = 32.3 bits (72), Expect = 1.6
Identities = 24/104 (23%), Positives = 43/104 (41%), Gaps = 16/104 (15%)
Query: 335 ECGQGEQASEKNECISEDMGD-----EDKEERQESRASDWHSKTKDFQESSIKSLKEKLL 389
E G G + E+ E E+ G E++EE +E + S +++ E S + + E+ +
Sbjct: 285 ESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEM 344
Query: 390 LEEE-----------PTTSHGQSSQGIVEETSEEGNSVPASQSV 422
E+E P + + S E E G P S ++
Sbjct: 345 SEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSAL 388
>gi|6005757 chromatin-specific transcription elongation factor large
subunit [Homo sapiens]
Length = 1047
Score = 39.7 bits (91), Expect = 0.010
Identities = 28/109 (25%), Positives = 57/109 (52%), Gaps = 7/109 (6%)
Query: 21 DVETTSSVSVKRKRRLEDAFIVISDSDGEEPKEENGLQKTKTKQSNRAKCLAKRKIAQMT 80
D + ++V K+++++ I + + D EE +EE + + +RA L +R +MT
Sbjct: 410 DEDGPATVLTSVKKKVKNVGIFLKNEDEEEEEEEKDEAEDLLGRGSRAALLTERTRNEMT 469
Query: 81 EEE-----QFALALKMSEQEAREVNSQEEEEEELLRKAIAESLNSCRPS 124
EE Q LA +++E+ R + Q+ E++ ++KA +++ PS
Sbjct: 470 AEEKRRAHQKELAAQLNEEAKRRLTEQKGEQQ--IQKARKSNVSYKNPS 516
>gi|189011568 adenomatous polyposis coli [Homo sapiens]
Length = 2843
Score = 39.7 bits (91), Expect = 0.010
Identities = 43/190 (22%), Positives = 79/190 (41%), Gaps = 9/190 (4%)
Query: 43 ISDSDGEEPKEENGLQKTKTKQSNRAKCLAKRKIAQMTEEEQFALALKMSEQEA--REVN 100
+S + P+ E+ K + +N K ++++M+ + SE+ R+
Sbjct: 2384 LSKNASSIPRSESA-SKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQST 2442
Query: 101 SQEEEEEELLRKAIAESLN--SCRPSDASATRSRPLATGP---SSQSHQEKTTDSGLTEG 155
+E LR+ + ES + S PS A+ +R A P S +T S + G
Sbjct: 2443 FIKEAPSPTLRRKLEESASFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAG 2502
Query: 156 IWQLVPPSLFKGSHISQGNEAEEREEPWDHTEKTEEEPVSGSSGSWDQSSQPVFENVNVK 215
W+ +PP+L + G A+ + H+E P++ SG+W + ++
Sbjct: 2503 GWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPIN-RSGTWKREHSKHSSSLPRV 2561
Query: 216 SFDRCTGHSA 225
S R TG S+
Sbjct: 2562 STWRRTGSSS 2571
>gi|189011566 adenomatous polyposis coli [Homo sapiens]
Length = 2843
Score = 39.7 bits (91), Expect = 0.010
Identities = 43/190 (22%), Positives = 79/190 (41%), Gaps = 9/190 (4%)
Query: 43 ISDSDGEEPKEENGLQKTKTKQSNRAKCLAKRKIAQMTEEEQFALALKMSEQEA--REVN 100
+S + P+ E+ K + +N K ++++M+ + SE+ R+
Sbjct: 2384 LSKNASSIPRSESA-SKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQST 2442
Query: 101 SQEEEEEELLRKAIAESLN--SCRPSDASATRSRPLATGP---SSQSHQEKTTDSGLTEG 155
+E LR+ + ES + S PS A+ +R A P S +T S + G
Sbjct: 2443 FIKEAPSPTLRRKLEESASFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAG 2502
Query: 156 IWQLVPPSLFKGSHISQGNEAEEREEPWDHTEKTEEEPVSGSSGSWDQSSQPVFENVNVK 215
W+ +PP+L + G A+ + H+E P++ SG+W + ++
Sbjct: 2503 GWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPIN-RSGTWKREHSKHSSSLPRV 2561
Query: 216 SFDRCTGHSA 225
S R TG S+
Sbjct: 2562 STWRRTGSSS 2571
>gi|53759122 adenomatous polyposis coli [Homo sapiens]
Length = 2843
Score = 39.7 bits (91), Expect = 0.010
Identities = 43/190 (22%), Positives = 79/190 (41%), Gaps = 9/190 (4%)
Query: 43 ISDSDGEEPKEENGLQKTKTKQSNRAKCLAKRKIAQMTEEEQFALALKMSEQEA--REVN 100
+S + P+ E+ K + +N K ++++M+ + SE+ R+
Sbjct: 2384 LSKNASSIPRSESA-SKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQST 2442
Query: 101 SQEEEEEELLRKAIAESLN--SCRPSDASATRSRPLATGP---SSQSHQEKTTDSGLTEG 155
+E LR+ + ES + S PS A+ +R A P S +T S + G
Sbjct: 2443 FIKEAPSPTLRRKLEESASFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAG 2502
Query: 156 IWQLVPPSLFKGSHISQGNEAEEREEPWDHTEKTEEEPVSGSSGSWDQSSQPVFENVNVK 215
W+ +PP+L + G A+ + H+E P++ SG+W + ++
Sbjct: 2503 GWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPIN-RSGTWKREHSKHSSSLPRV 2561
Query: 216 SFDRCTGHSA 225
S R TG S+
Sbjct: 2562 STWRRTGSSS 2571
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 39.7 bits (91), Expect = 0.010
Identities = 51/234 (21%), Positives = 102/234 (43%), Gaps = 17/234 (7%)
Query: 1 MPRRKKKVKEVSESRNLEKKDVETTSSVSVKRKRRLEDAFIVISDSDGEEPKEENGLQKT 60
+ ++ +E E+ E+++ + + + +D +S++ E+ + ++ ++T
Sbjct: 1041 LSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEAS-EKDEGDSDEEET 1099
Query: 61 KTKQSNRAKCLAKRKIAQMTEEEQFALALKMSEQEAREVNSQEEEEEELLRKAIA-ESLN 119
+ +++A+ + + ++ +E E + + S ++ EV ++EEEEEE + +A ES+
Sbjct: 1100 VSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEMVAEESMA 1159
Query: 120 SCRPSDASAT-RSRPLATG-PSSQSHQEKTTDSGLTEGIWQLVPPSLFKGSHISQGNE-- 175
S P D LA G P+ S + TE + PS+ + G E
Sbjct: 1160 SAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEEP 1219
Query: 176 AEEREEPWDHTEKTEEEPVSGSSGSWDQSSQPVFENVNVK---SFDRCTGHSAE 226
A+ RE P EEP G+ S +P + V + S +R H E
Sbjct: 1220 ADSREPP--------EEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLE 1265
Score = 35.8 bits (81), Expect = 0.14
Identities = 53/232 (22%), Positives = 87/232 (37%), Gaps = 7/232 (3%)
Query: 318 KGFGEPVLPRPPSLIQNECGQGEQASEKNECISEDMGDEDKEERQESRASDWHSKTKDFQ 377
KG G P P + + + E+ S E S + +E +EE +E D S +D
Sbjct: 1015 KGVGVRRRPARPLELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDES 1074
Query: 378 ESSIKSLKEKLLLEEEPTTSHGQSSQGIVEETSEEGNSVPASQSVAALTSKRSLVLMPES 437
E+ + E++ S + + IV +E +S +S+S +S S E
Sbjct: 1075 ENDDEDTALSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSED 1134
Query: 438 SAEEITVCPETQLSSSETFDLEREVSPGSRDI-LDGVRIIMA-DKEVGNKEDAEKEVAIS 495
E + E + E E S G D DG +A + E+EV I
Sbjct: 1135 EEEVVAREEEEEEEEEEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIE 1194
Query: 496 TFSSSNQVSCPLCDQCFPPTKIE-----RHAMYCNGLMEEDTVLTRRQKEAK 542
T + + + + D+ P +E R GL +E +L + AK
Sbjct: 1195 TEAVAPEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAK 1246
>gi|114205399 cyclic nucleotide gated channel beta 1 isoform a [Homo
sapiens]
Length = 1251
Score = 39.3 bits (90), Expect = 0.013
Identities = 43/175 (24%), Positives = 64/175 (36%), Gaps = 17/175 (9%)
Query: 50 EPKEENGLQKTKTKQSNRAKCLAKRKIAQMTEEEQFALALKMSEQEAREVNSQEEEEEEL 109
EP E+ Q T A + + E+ L+ ++ E++ E +EEEEEE
Sbjct: 310 EPPWEDAHQDVSTSPQGTEVVPAYEEENKAVEKMPRELS-RIEEEKEDEEEEEEEEEEEE 368
Query: 110 LRKAIAESLNSCRPSDASATRSRPLATGPSSQSHQEKTTDSGLTEGIWQLVPPSLFKGSH 169
+ L+SC S +S T P S S Q+ +W+ V K +
Sbjct: 369 EEEVTEVLLDSCVVSQVGVGQSEEDGTRPQSTSDQK----------LWEEVGEEAKKEAE 418
Query: 170 ISQGNEAEE------REEPWDHTEKTEEEPVSGSSGSWDQSSQPVFENVNVKSFD 218
EAEE +EP D E EE + S + V V+ D
Sbjct: 419 EKAKEEAEEVAEEEAEKEPQDWAETKEEPEAEAEAASSGVPATKQHPEVQVEDTD 473
>gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]
Length = 2039
Score = 39.3 bits (90), Expect = 0.013
Identities = 42/196 (21%), Positives = 81/196 (41%), Gaps = 25/196 (12%)
Query: 6 KKVKEVSESRNLEKKDVETTSSVS-VKRKRRLEDAFIVISDSDGEEPKEENGLQKTKTKQ 64
+K K++ EK ++ + V +K K +L +GE+ K ++KT ++
Sbjct: 819 EKEKKIKHEHKSEKDKLDLSECVDKIKEKDKLYSHHTEKCHKEGEKSKNTAAIKKTDDRE 878
Query: 65 SNRAKCLAKRKIAQMTEEEQFALALKMSEQEAREVNSQEEEEEELLRKAIAESLNS-CRP 123
+R K K E+ +E + E +E+ L+ K +S NS
Sbjct: 879 KSREKMDRKHD----------------KEKPEKERHLAESKEKHLMEKKNKQSDNSEYSK 922
Query: 124 SDASATRSRPLATGPSSQSHQEKTTDSGLTEGIWQLVPPSLFKGSHISQGNEAEEREEPW 183
S+ + + +S +++ + ++ I + K S I GN+A + E+P
Sbjct: 923 SEKGKNKEKDRELDKKEKSRDKESINITNSKHIQE------EKKSSIVDGNKA-QHEKPL 975
Query: 184 DHTEKTEEEPVSGSSG 199
EKT++EP+ G
Sbjct: 976 SLKEKTKDEPLKTPDG 991
Score = 32.7 bits (73), Expect = 1.2
Identities = 22/96 (22%), Positives = 43/96 (44%), Gaps = 3/96 (3%)
Query: 3 RRKKKVKEVSESRNLEKKDVETTSSVSVKRKRRLEDAFIVISDSDGEEPKEENGLQKTKT 62
+ K K+ S++ +E+ DV KR+L + + + E+ G +K KT
Sbjct: 29 KSKDKIASYSKTPKIERSDVSKEMKEKSSMKRKLPFTISPSRNEERDSDTEKEGPEKKKT 88
Query: 63 KQSNRAKCLAKRKIA---QMTEEEQFALALKMSEQE 95
K+ K I ++E +Q AL ++M+ ++
Sbjct: 89 KKEAGNKKSTPVSILFGYPLSERKQMALLMQMTARD 124
>gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]
Length = 2062
Score = 39.3 bits (90), Expect = 0.013
Identities = 42/196 (21%), Positives = 81/196 (41%), Gaps = 25/196 (12%)
Query: 6 KKVKEVSESRNLEKKDVETTSSVS-VKRKRRLEDAFIVISDSDGEEPKEENGLQKTKTKQ 64
+K K++ EK ++ + V +K K +L +GE+ K ++KT ++
Sbjct: 842 EKEKKIKHEHKSEKDKLDLSECVDKIKEKDKLYSHHTEKCHKEGEKSKNTAAIKKTDDRE 901
Query: 65 SNRAKCLAKRKIAQMTEEEQFALALKMSEQEAREVNSQEEEEEELLRKAIAESLNS-CRP 123
+R K K E+ +E + E +E+ L+ K +S NS
Sbjct: 902 KSREKMDRKHD----------------KEKPEKERHLAESKEKHLMEKKNKQSDNSEYSK 945
Query: 124 SDASATRSRPLATGPSSQSHQEKTTDSGLTEGIWQLVPPSLFKGSHISQGNEAEEREEPW 183
S+ + + +S +++ + ++ I + K S I GN+A + E+P
Sbjct: 946 SEKGKNKEKDRELDKKEKSRDKESINITNSKHIQE------EKKSSIVDGNKA-QHEKPL 998
Query: 184 DHTEKTEEEPVSGSSG 199
EKT++EP+ G
Sbjct: 999 SLKEKTKDEPLKTPDG 1014
>gi|24308089 chromodomain helicase DNA binding protein 5 [Homo
sapiens]
Length = 1954
Score = 39.3 bits (90), Expect = 0.013
Identities = 25/92 (27%), Positives = 45/92 (48%), Gaps = 5/92 (5%)
Query: 323 PVLPRPPSLIQNEC-GQGEQASEKNECISEDMGDEDKEERQESRASDWHSKTKDFQESSI 381
P +P L +N+C G+ ++ N+ +SE+ +ED EE+ ES SD+ K ++ +
Sbjct: 48 PKKKKPKKLKENKCKGKRKKKEGSNDELSEN--EEDLEEKSESEGSDYSPNKK--KKKKL 103
Query: 382 KSLKEKLLLEEEPTTSHGQSSQGIVEETSEEG 413
K KEK ++ + G ++E G
Sbjct: 104 KDKKEKKAKRKKKDEDEDDNDDGCLKEPKSSG 135
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 38.5 bits (88), Expect = 0.022
Identities = 39/210 (18%), Positives = 84/210 (40%), Gaps = 6/210 (2%)
Query: 5 KKKVKEVSESRNLEKKDVETTSSVSVKRKRRLEDAFIVISDSDGEEPKEENGLQKTKTKQ 64
K++ K +E+++ EK++ ++ + V K + S + + P++E + K
Sbjct: 521 KEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKS 580
Query: 65 SNRAKCLAKRKIAQMTEEEQFALALKMSEQEARE-VNSQEEEEEELLRKAIAESLNSCRP 123
+AK AK + E + A ++EA+ ++ +EE A +S +
Sbjct: 581 PEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKS 640
Query: 124 SDASATRSRPLATGPSSQSHQEKTTDSGLTEGIWQLVPPSLFKGSHISQGNEAEEREEPW 183
+S A P + + K+ + + + P K ++ E+ + P
Sbjct: 641 PTKEEAKSPEKAKSP--EKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPV 698
Query: 184 DHTEKTEEE---PVSGSSGSWDQSSQPVFE 210
K+ E+ PV + S +++ PV E
Sbjct: 699 KEEAKSPEKAKSPVKEEAKSPEKAKSPVKE 728
Score = 32.0 bits (71), Expect = 2.1
Identities = 104/570 (18%), Positives = 208/570 (36%), Gaps = 76/570 (13%)
Query: 5 KKKVKEVSESRNL----EKKDVETTSSVSVKRKRRLEDAFIVISDSDGEEPKEENGLQKT 60
K KV E SE + + ++ + T V+ + ++ ++ + GEE + E G ++T
Sbjct: 443 KIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGK-EEEGGEEEEAEGGEEET 501
Query: 61 KTKQSNRAKCLAKRKIAQMTEEEQFALALKMSEQEAREVNSQEEEEEELLRKAIAESLNS 120
K+ + A K + + EE + K E+E + ++ + E+ A E+ +
Sbjct: 502 KSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKS- 560
Query: 121 CRPSDASATRSRPLATGPSSQSHQEKTTDSGLTEGIWQLVPPSLFKGSHISQGNEAEERE 180
P +A + A P+ EK E P+ K ++ EE +
Sbjct: 561 --PPEAKSPEKEE-AKSPAEVKSPEKAKSPAKEEA----KSPAEAKSPEKAKSPVKEEAK 613
Query: 181 EPWDHTEKTEEEPVSGSS-GSWDQSSQPVFENVNVKSFDRCTGHSAEHTQCGKPQESTGR 239
P + +EE S + S +++ P E KS ++ S E + P+++
Sbjct: 614 SPAEAKSPVKEEAKSPAEVKSPEKAKSPTKE--EAKSPEK--AKSPEKEEAKSPEKAKSP 669
Query: 240 GSAFLKAVQGSGDTSRHCLPTLADAKGLQDTGGTVNYFWGIPFCPDGVDPNQYTKVILCQ 299
A K+ + + P A+AK + P + P + + +
Sbjct: 670 VKAEAKSPEKAKS------PVKAEAKSPEKAKS--------PVKEEAKSPEKAKSPVKEE 715
Query: 300 LEVYQKSLKMAQRQLLNKKGFGEPVLPRPPSLIQNECGQGEQASEKNECISEDMGDEDKE 359
+ +K+ + + + PV + E E+A + + D+ + +
Sbjct: 716 AKSPEKAKSPVKEEAKTPEKAKSPV--------KEEAKSPEKAKSPEKAKTLDVKSPEAK 767
Query: 360 ERQESRASDWHSKTKDFQESSIKSLKEKLLLEEEPTTSHGQSSQGIVEETSEEGNSVPAS 419
+ A S F E + +KE++ E ++ + E+ +P
Sbjct: 768 TPAKEEA---RSPADKFPEKAKSPVKEEVKSPE-------KAKSPLKEDAKAPEKEIPKK 817
Query: 420 QSVAALTSKRS-----LVLMPESSAEEITVCPETQLSSSETFDLEREVSP---GSRDILD 471
+ V + + V P AEE P T + E D ++E +P + ++
Sbjct: 818 EEVKSPVKEEEKPQEVKVKEPPKKAEE-EKAPATP-KTEEKKDSKKEEAPKKEAPKPKVE 875
Query: 472 GVRIIMADKEVGNKEDAEKEVAISTFSSSNQVSCPLCDQCFPPTKIERHAMYCNGLMEED 531
+ +K +K +A+KE A +V P + P K+E ++ED
Sbjct: 876 EKKEPAVEKPKESKVEAKKEEA----EDKKKVPTP---EKEAPAKVE---------VKED 919
Query: 532 TVLTRRQKEAKTKSDSGTAAQTSLDIDKNE 561
+ + AK + D A + S +K E
Sbjct: 920 AKPKEKTEVAKKEPDDAKAKEPSKPAEKKE 949
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 37.7 bits (86), Expect = 0.037
Identities = 52/262 (19%), Positives = 93/262 (35%), Gaps = 20/262 (7%)
Query: 3 RRKKKVKEVSESRNLEKKDVETTSSVSVKRKRRLEDAFIVISDSDGEEPKEENGLQKTKT 62
R + K + S+SR+ KK+ + S R R D E K +N K
Sbjct: 227 RSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKP 286
Query: 63 KQSNRAKCLAKRKIAQMTEEEQFALALKMSEQEAREVNSQEEEEEELLRKAIAESLNSCR 122
K + ++ +K K ++E + E+E R S+ +E+ LR++ + S R
Sbjct: 287 KSRSPSRHKSKSKSRSRSQERRV-------EEEKRGSVSRGRSQEKSLRQSRSRS----R 335
Query: 123 PSDASATRSRPLATGPSSQSHQEKTTDSGLTEGIWQLVPPSLFK---------GSHISQG 173
S +RSR + + ++++ + + + K GS +
Sbjct: 336 SKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKK 395
Query: 174 NEAEEREEPWDHTEKTEEEPVSGSSGSWDQSSQPVFENVNVKSFDRCTGHSAEHTQCGKP 233
E +R + + +E S S + + EN R S ++ P
Sbjct: 396 KEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLP 455
Query: 234 QESTGRGSAFLKAVQGSGDTSR 255
ES R + K S SR
Sbjct: 456 SESRSRSKSASKTRSRSKSRSR 477
>gi|157502225 Janus kinase and microtubule interacting protein 3
[Homo sapiens]
Length = 844
Score = 37.7 bits (86), Expect = 0.037
Identities = 32/149 (21%), Positives = 63/149 (42%), Gaps = 3/149 (2%)
Query: 9 KEVSESRNLEKKDVETTSSVSVKRKRRLEDAFIVISDSDGEEPKEENGLQKTKTKQSNRA 68
+E + +EK ++ S KR++E+A ++ +D + E + ++ R
Sbjct: 141 EEAKKGFEVEKVKMQQEISELKGAKRQVEEALTLVIQADKIKAAEIRSVYHLHQEEITRI 200
Query: 69 KCLAKRKIAQMTEEEQFALALKMSEQEAREVNSQEEEEEELLRKAIAESLNSCRPSD--- 125
K +R+I ++ EE +F + V + + +L ++A+ E L+ R +D
Sbjct: 201 KKECEREIRRLMEEIKFKDRAVFVLERELGVQAGHAQRLQLQKEALDEQLSQVREADRHP 260
Query: 126 ASATRSRPLATGPSSQSHQEKTTDSGLTE 154
S R P A G S + + L E
Sbjct: 261 GSPRRELPHAAGAGDASDHSGSPEQQLDE 289
>gi|22538461 nuclear receptor co-repressor 1 [Homo sapiens]
Length = 2440
Score = 37.7 bits (86), Expect = 0.037
Identities = 30/127 (23%), Positives = 57/127 (44%), Gaps = 5/127 (3%)
Query: 351 EDMGDEDKEERQESRASDWHSKTKDFQESSIKSLKEKLLLEEEPTTSHGQSSQGIVEETS 410
ED+ ++EE E + ++D E++ + +E EPTT S+ + S
Sbjct: 712 EDIEASNEEENPEDSEVEAVKPSEDSPENATSRGNTEPAVELEPTTETAPSTSPSLAVPS 771
Query: 411 -----EEGNSVPASQSVAALTSKRSLVLMPESSAEEITVCPETQLSSSETFDLEREVSPG 465
+E + S++A T+++ V E SAEE +VC + +++ D+E V
Sbjct: 772 TKPAEDESVETQVNDSISAETAEQMDVDQQEHSAEEGSVCDPPPATKADSVDVEVRVPEN 831
Query: 466 SRDILDG 472
++G
Sbjct: 832 HASKVEG 838
Score = 33.5 bits (75), Expect = 0.71
Identities = 20/85 (23%), Positives = 36/85 (42%), Gaps = 4/85 (4%)
Query: 345 KNECISEDMGDEDKEERQESRASDWHSKTKDFQESSIKSLKEKLLLEEEPTTSHGQSSQG 404
+N+ I+ +E EE++E +A K ++ ++ K KE + + T G
Sbjct: 501 RNQQIARPSQEEKVEEKEEDKAEKTEKKEEEKKDEEEKDEKE----DSKENTKEKDKIDG 556
Query: 405 IVEETSEEGNSVPASQSVAALTSKR 429
EET E + P + A +R
Sbjct: 557 TAEETEEREQATPRGRKTANSQGRR 581
>gi|34482047 adaptor-related protein complex 3, beta 2 subunit [Homo
sapiens]
Length = 1082
Score = 37.7 bits (86), Expect = 0.037
Identities = 39/135 (28%), Positives = 58/135 (42%), Gaps = 13/135 (9%)
Query: 334 NECGQGEQASEKNECISEDMGDEDKEERQESRASDWHSKTKDFQESSIKSLKEKLLLEEE 393
+E G GE +SE + +ED DED+E+ + S + K + + K + +E
Sbjct: 707 SESGSGESSSESD---NEDQ-DEDEEKGRGSESEQSEEDGKRKTKKKVPERKGEASSSDE 762
Query: 394 PTTSHGQSSQGIVEETSEEGNSVPASQSVAALTSKRSLVLMPESS---AEEIT------V 444
+ S SS+ + SEE PAS S S +S E S E+ T V
Sbjct: 763 GSDSSSSSSESEMTSESEEEQLEPASWSRKTPPSSKSAPATKEISLLDLEDFTPPSVQPV 822
Query: 445 CPETQLSSSETFDLE 459
P +S+S DLE
Sbjct: 823 SPPAIVSTSLAADLE 837
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.125 0.351
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,258,481
Number of Sequences: 37866
Number of extensions: 1426641
Number of successful extensions: 8738
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 48
Number of HSP's successfully gapped in prelim test: 329
Number of HSP's that attempted gapping in prelim test: 7036
Number of HSP's gapped (non-prelim): 1656
length of query: 719
length of database: 18,247,518
effective HSP length: 110
effective length of query: 609
effective length of database: 14,082,258
effective search space: 8576095122
effective search space used: 8576095122
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.