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Search of human proteins with 42476101
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|42476101 TFIIA alpha, p55 isoform 2 [Homo sapiens]
(337 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|42476101 TFIIA alpha, p55 isoform 2 [Homo sapiens] 676 0.0
gi|7706735 TFIIA alpha, p55 isoform 1 [Homo sapiens] 676 0.0
gi|29553944 STON1-GTF2A1L protein [Homo sapiens] 135 7e-32
gi|26787968 general transcription factor IIA, 1-like isoform 1 [... 135 7e-32
gi|26787966 general transcription factor IIA, 1-like isoform 2 [... 71 1e-12
gi|221139761 zinc finger protein 853 [Homo sapiens] 60 3e-09
gi|56549696 E1A binding protein p400 [Homo sapiens] 54 3e-07
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 53 3e-07
gi|166064029 angiomotin isoform 1 [Homo sapiens] 53 3e-07
gi|17975763 myelin transcription factor 1 [Homo sapiens] 53 4e-07
gi|60498973 myelin transcription factor 1-like [Homo sapiens] 53 4e-07
gi|20336260 retinoblastoma protein-binding zinc finger protein i... 52 6e-07
gi|20336258 retinoblastoma protein-binding zinc finger protein i... 52 6e-07
gi|55953110 retinoblastoma protein-binding zinc finger protein i... 52 8e-07
gi|56549668 AT rich interactive domain 2 (ARID, RFX-like) [Homo ... 52 1e-06
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] 51 1e-06
gi|4507379 TATA box binding protein [Homo sapiens] 50 2e-06
gi|38787935 BMP-2 inducible kinase isoform a [Homo sapiens] 50 4e-06
gi|38787904 BMP-2 inducible kinase isoform b [Homo sapiens] 50 4e-06
gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens] 50 4e-06
gi|17017963 forkhead box P2 isoform I [Homo sapiens] 49 6e-06
gi|22538413 forkhead box P2 isoform III [Homo sapiens] 49 6e-06
gi|149999352 forkhead box P2 isoform II [Homo sapiens] 49 6e-06
gi|55956788 nucleolin [Homo sapiens] 49 6e-06
gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens] 49 6e-06
gi|21735415 centromere protein B [Homo sapiens] 48 1e-05
gi|156071452 nardilysin isoform b [Homo sapiens] 48 1e-05
gi|156071450 nardilysin isoform a [Homo sapiens] 48 1e-05
gi|62953127 polyhomeotic 1-like [Homo sapiens] 48 1e-05
gi|157743257 POU domain, class 6, transcription factor 2 [Homo s... 47 2e-05
>gi|42476101 TFIIA alpha, p55 isoform 2 [Homo sapiens]
Length = 337
Score = 676 bits (1743), Expect = 0.0
Identities = 337/337 (100%), Positives = 337/337 (100%)
Query: 1 MELKTLWENKLMQSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQ 60
MELKTLWENKLMQSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQ
Sbjct: 1 MELKTLWENKLMQSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQ 60
Query: 61 AQTQQVLIPASQQATAPQVIVPDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNS 120
AQTQQVLIPASQQATAPQVIVPDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNS
Sbjct: 61 AQTQQVLIPASQQATAPQVIVPDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNS 120
Query: 121 GQLLQVVRAANGAQYIFQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGV 180
GQLLQVVRAANGAQYIFQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGV
Sbjct: 121 GQLLQVVRAANGAQYIFQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGV 180
Query: 181 IIQPQQILFTGNKTQVIPTTVAAPTPAQAQITATGQQQPQAQPAQTQAPLVLQVDGTGDT 240
IIQPQQILFTGNKTQVIPTTVAAPTPAQAQITATGQQQPQAQPAQTQAPLVLQVDGTGDT
Sbjct: 181 IIQPQQILFTGNKTQVIPTTVAAPTPAQAQITATGQQQPQAQPAQTQAPLVLQVDGTGDT 240
Query: 241 SSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTENVVVCQY 300
SSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTENVVVCQY
Sbjct: 241 SSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTENVVVCQY 300
Query: 301 DKIHRSKNKWKFHLKDGIMNLNGRDYIFSKAIGDAEW 337
DKIHRSKNKWKFHLKDGIMNLNGRDYIFSKAIGDAEW
Sbjct: 301 DKIHRSKNKWKFHLKDGIMNLNGRDYIFSKAIGDAEW 337
>gi|7706735 TFIIA alpha, p55 isoform 1 [Homo sapiens]
Length = 376
Score = 676 bits (1743), Expect = 0.0
Identities = 337/337 (100%), Positives = 337/337 (100%)
Query: 1 MELKTLWENKLMQSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQ 60
MELKTLWENKLMQSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQ
Sbjct: 40 MELKTLWENKLMQSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQ 99
Query: 61 AQTQQVLIPASQQATAPQVIVPDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNS 120
AQTQQVLIPASQQATAPQVIVPDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNS
Sbjct: 100 AQTQQVLIPASQQATAPQVIVPDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNS 159
Query: 121 GQLLQVVRAANGAQYIFQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGV 180
GQLLQVVRAANGAQYIFQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGV
Sbjct: 160 GQLLQVVRAANGAQYIFQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGV 219
Query: 181 IIQPQQILFTGNKTQVIPTTVAAPTPAQAQITATGQQQPQAQPAQTQAPLVLQVDGTGDT 240
IIQPQQILFTGNKTQVIPTTVAAPTPAQAQITATGQQQPQAQPAQTQAPLVLQVDGTGDT
Sbjct: 220 IIQPQQILFTGNKTQVIPTTVAAPTPAQAQITATGQQQPQAQPAQTQAPLVLQVDGTGDT 279
Query: 241 SSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTENVVVCQY 300
SSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTENVVVCQY
Sbjct: 280 SSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTENVVVCQY 339
Query: 301 DKIHRSKNKWKFHLKDGIMNLNGRDYIFSKAIGDAEW 337
DKIHRSKNKWKFHLKDGIMNLNGRDYIFSKAIGDAEW
Sbjct: 340 DKIHRSKNKWKFHLKDGIMNLNGRDYIFSKAIGDAEW 376
>gi|29553944 STON1-GTF2A1L protein [Homo sapiens]
Length = 1182
Score = 135 bits (339), Expect = 7e-32
Identities = 68/133 (51%), Positives = 87/133 (65%), Gaps = 26/133 (19%)
Query: 231 VLQVDGTGDTSSEEDEDEEEDYDDDE-------------EEDKEKDGAEDGQ-------- 269
++QVDG+GDTSS E+ D D++E EE+ + ED
Sbjct: 1050 IIQVDGSGDTSSNEEIGSTRDADENEFLGNIDGGDLKVPEEEADSISNEDSATNSSDNED 1109
Query: 270 -----VEEEPLNSEDDVSDEEGQELFDTENVVVCQYDKIHRSKNKWKFHLKDGIMNLNGR 324
VEE+PLNS DDVS+++ +LFDT+NV+VCQYDKIHRSKNKWKF+LKDG+M GR
Sbjct: 1110 PQVNIVEEDPLNSGDDVSEQDVPDLFDTDNVIVCQYDKIHRSKNKWKFYLKDGVMCFGGR 1169
Query: 325 DYIFSKAIGDAEW 337
DY+F+KAIGDAEW
Sbjct: 1170 DYVFAKAIGDAEW 1182
Score = 44.3 bits (103), Expect = 2e-04
Identities = 70/257 (27%), Positives = 102/257 (39%), Gaps = 56/257 (21%)
Query: 2 ELKTLWENKLMQSRAV-DGFHSEEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQ 60
+LK LWE K++QS+A D F + Q L +Q H Q Q
Sbjct: 742 DLKQLWETKVLQSKATEDFFRNSIQSPLFTLQLPHSLHQ------------------TLQ 783
Query: 61 AQTQQVLIPASQQATAPQVIVPDSKLIQHMNASNMSAAAT--AATLALPAGVTPVQQILT 118
+ T ++IPA + T P + + SN SA T + +PAGVT + T
Sbjct: 784 SSTASLVIPAGR--TLPSFTTAE------LGTSNSSANFTFPGYPIHVPAGVT----LQT 831
Query: 119 NSGQLLQV-----VRAANGAQYIFQ-PQQSVVLQ-------QQVIPQMQPGGVQAPV--- 162
SG L +V V +G I Q P Q V Q Q +PQ+ P +QA
Sbjct: 832 VSGHLYKVNVPIMVTETSGRAGILQHPIQQVFQQLGQPSVIQTSVPQLNPWSLQATTEKS 891
Query: 163 --IQQVL---APLPGGISPQTGVIIQPQQILFT-GNKTQVIPTTVAAPTPAQAQITATGQ 216
I+ VL A LP G + + IL + GN+ +++P + + I+ G
Sbjct: 892 QRIETVLQQPAILPSGPVDRKHLENATSDILVSPGNEHKIVPEALLCHQESSHYISLPGV 951
Query: 217 Q-QPQAQPAQTQAPLVL 232
PQ + VL
Sbjct: 952 VFSPQVSQTNSNVESVL 968
>gi|26787968 general transcription factor IIA, 1-like isoform 1
[Homo sapiens]
Length = 478
Score = 135 bits (339), Expect = 7e-32
Identities = 68/133 (51%), Positives = 87/133 (65%), Gaps = 26/133 (19%)
Query: 231 VLQVDGTGDTSSEEDEDEEEDYDDDE-------------EEDKEKDGAEDGQ-------- 269
++QVDG+GDTSS E+ D D++E EE+ + ED
Sbjct: 346 IIQVDGSGDTSSNEEIGSTRDADENEFLGNIDGGDLKVPEEEADSISNEDSATNSSDNED 405
Query: 270 -----VEEEPLNSEDDVSDEEGQELFDTENVVVCQYDKIHRSKNKWKFHLKDGIMNLNGR 324
VEE+PLNS DDVS+++ +LFDT+NV+VCQYDKIHRSKNKWKF+LKDG+M GR
Sbjct: 406 PQVNIVEEDPLNSGDDVSEQDVPDLFDTDNVIVCQYDKIHRSKNKWKFYLKDGVMCFGGR 465
Query: 325 DYIFSKAIGDAEW 337
DY+F+KAIGDAEW
Sbjct: 466 DYVFAKAIGDAEW 478
Score = 44.3 bits (103), Expect = 2e-04
Identities = 70/257 (27%), Positives = 102/257 (39%), Gaps = 56/257 (21%)
Query: 2 ELKTLWENKLMQSRAV-DGFHSEEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQ 60
+LK LWE K++QS+A D F + Q L +Q H Q Q
Sbjct: 38 DLKQLWETKVLQSKATEDFFRNSIQSPLFTLQLPHSLHQ------------------TLQ 79
Query: 61 AQTQQVLIPASQQATAPQVIVPDSKLIQHMNASNMSAAAT--AATLALPAGVTPVQQILT 118
+ T ++IPA + T P + + SN SA T + +PAGVT + T
Sbjct: 80 SSTASLVIPAGR--TLPSFTTAE------LGTSNSSANFTFPGYPIHVPAGVT----LQT 127
Query: 119 NSGQLLQV-----VRAANGAQYIFQ-PQQSVVLQ-------QQVIPQMQPGGVQAPV--- 162
SG L +V V +G I Q P Q V Q Q +PQ+ P +QA
Sbjct: 128 VSGHLYKVNVPIMVTETSGRAGILQHPIQQVFQQLGQPSVIQTSVPQLNPWSLQATTEKS 187
Query: 163 --IQQVL---APLPGGISPQTGVIIQPQQILFT-GNKTQVIPTTVAAPTPAQAQITATGQ 216
I+ VL A LP G + + IL + GN+ +++P + + I+ G
Sbjct: 188 QRIETVLQQPAILPSGPVDRKHLENATSDILVSPGNEHKIVPEALLCHQESSHYISLPGV 247
Query: 217 Q-QPQAQPAQTQAPLVL 232
PQ + VL
Sbjct: 248 VFSPQVSQTNSNVESVL 264
>gi|26787966 general transcription factor IIA, 1-like isoform 2
[Homo sapiens]
Length = 453
Score = 71.2 bits (173), Expect = 1e-12
Identities = 40/98 (40%), Positives = 55/98 (56%), Gaps = 26/98 (26%)
Query: 231 VLQVDGTGDTSSEEDEDEEEDYDDDE-------------EEDKEKDGAEDGQ-------- 269
++QVDG+GDTSS E+ D D++E EE+ + ED
Sbjct: 346 IIQVDGSGDTSSNEEIGSTRDADENEFLGNIDGGDLKVPEEEADSISNEDSATNSSDNED 405
Query: 270 -----VEEEPLNSEDDVSDEEGQELFDTENVVVCQYDK 302
VEE+PLNS DDVS+++ +LFDT+NV+VCQYDK
Sbjct: 406 PQVNIVEEDPLNSGDDVSEQDVPDLFDTDNVIVCQYDK 443
Score = 44.3 bits (103), Expect = 2e-04
Identities = 70/257 (27%), Positives = 102/257 (39%), Gaps = 56/257 (21%)
Query: 2 ELKTLWENKLMQSRAV-DGFHSEEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQ 60
+LK LWE K++QS+A D F + Q L +Q H Q Q
Sbjct: 38 DLKQLWETKVLQSKATEDFFRNSIQSPLFTLQLPHSLHQ------------------TLQ 79
Query: 61 AQTQQVLIPASQQATAPQVIVPDSKLIQHMNASNMSAAAT--AATLALPAGVTPVQQILT 118
+ T ++IPA + T P + + SN SA T + +PAGVT + T
Sbjct: 80 SSTASLVIPAGR--TLPSFTTAE------LGTSNSSANFTFPGYPIHVPAGVT----LQT 127
Query: 119 NSGQLLQV-----VRAANGAQYIFQ-PQQSVVLQ-------QQVIPQMQPGGVQAPV--- 162
SG L +V V +G I Q P Q V Q Q +PQ+ P +QA
Sbjct: 128 VSGHLYKVNVPIMVTETSGRAGILQHPIQQVFQQLGQPSVIQTSVPQLNPWSLQATTEKS 187
Query: 163 --IQQVL---APLPGGISPQTGVIIQPQQILFT-GNKTQVIPTTVAAPTPAQAQITATGQ 216
I+ VL A LP G + + IL + GN+ +++P + + I+ G
Sbjct: 188 QRIETVLQQPAILPSGPVDRKHLENATSDILVSPGNEHKIVPEALLCHQESSHYISLPGV 247
Query: 217 Q-QPQAQPAQTQAPLVL 232
PQ + VL
Sbjct: 248 VFSPQVSQTNSNVESVL 264
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 60.1 bits (144), Expect = 3e-09
Identities = 73/292 (25%), Positives = 115/292 (39%), Gaps = 49/292 (16%)
Query: 24 EQQLLLQVQQQHQPQQQQHHHHHHHQQAQP--------QQTVPQQAQTQQVLIP-----A 70
+QQ QQQ QQ+ H HHQ+ +P QQ PQQ Q QQ L
Sbjct: 119 QQQPQQDGQQQLSQLQQEKHQSVHHQELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQLQ 178
Query: 71 SQQATAPQVIVPDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQLLQVVRAA 130
+QQA QV+ +L Q + + L QQ+L QL Q
Sbjct: 179 TQQAQEQQVLQQQEQLQQQVQEQQL--------LQQQQEQLQQQQLLQQQEQLQQ----- 225
Query: 131 NGAQYIFQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFT 190
Q Q Q+ + QQQ++ Q G +Q ++QQ A L + Q +Q Q +L
Sbjct: 226 ---QQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQ 282
Query: 191 GNKTQVIPTTVAAPTPAQAQITATGQQQPQAQPAQTQAP---------LVLQVDGTGDTS 241
+ Q Q Q QQQ Q Q Q Q P + L++ S
Sbjct: 283 QEQLQ-----------QQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGS 331
Query: 242 SEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTE 293
+E E + ++ + +E +++++ + +E L + +++ Q+L E
Sbjct: 332 EQELEQQRQELERQQELERQQEQRQLQLKLQEELQQLEQQLEQQQQQLEQQE 383
Score = 50.8 bits (120), Expect = 2e-06
Identities = 69/271 (25%), Positives = 103/271 (38%), Gaps = 17/271 (6%)
Query: 29 LQVQQ-QHQPQQQQHHHHHHHQQAQPQ---QTVPQQAQTQQV--LIPASQQATAPQVIVP 82
LQ+QQ + QP+ QQ H QQ QP Q PQQ QQ+ L Q+ Q + P
Sbjct: 89 LQLQQLEQQPEPQQQPQHEQLQQPQPHLELQQQPQQDGQQQLSQLQQEKHQSVHHQELKP 148
Query: 83 DSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQLLQVVRAANGAQYIFQPQQS 142
+ +L+ L +Q+ T Q QV++ Q Q QQ
Sbjct: 149 ELQLMHQQQQLQPQQVQEQQRLQ-----QQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQL 203
Query: 143 VVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVII-----QPQQILFTGNKTQVI 197
+ QQ+ + Q Q Q + QQ + Q +++ Q QQ L + Q +
Sbjct: 204 LQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQ-L 262
Query: 198 PTTVAAPTPAQAQITATGQQQPQAQPAQTQAPLVLQVDGTGDTSSEEDEDEEEDYDDDEE 257
+ AQ Q QQQ Q Q Q Q L Q + + E E+ ++ E
Sbjct: 263 QQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVEL 322
Query: 258 EDKEKDGAEDGQVEEEPLNSEDDVSDEEGQE 288
E D + ++E++ E E QE
Sbjct: 323 ELMPVDLGSEQELEQQRQELERQQELERQQE 353
Score = 30.8 bits (68), Expect = 1.8
Identities = 27/96 (28%), Positives = 41/96 (42%), Gaps = 13/96 (13%)
Query: 25 QQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIVPDS 84
Q+ L Q++QQ + QQQQ + P + QQ + Q L P + P+
Sbjct: 362 QEELQQLEQQLEQQQQQLEQQEVQLELTPVELGAQQQEVQLELTP----------VQPEL 411
Query: 85 KLIQHMNASNMSAA---ATAATLALPAGVTPVQQIL 117
+L A AA A AA + P G VQ+++
Sbjct: 412 QLELVPAAGGGGAAVPGAPAAVVVAPPGYVVVQELM 447
>gi|56549696 E1A binding protein p400 [Homo sapiens]
Length = 3122
Score = 53.5 bits (127), Expect = 3e-07
Identities = 61/200 (30%), Positives = 78/200 (39%), Gaps = 44/200 (22%)
Query: 28 LLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQ-QATAPQVIVPDSKL 86
LL+ QQQ Q QQQQ QQ Q QQ Q T QV +P Q QA +P I KL
Sbjct: 2716 LLRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTTTTSQVQVPQIQGQAQSPAQIKAVGKL 2775
Query: 87 IQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQLLQVVRAANGAQYIFQPQQSVVLQ 146
TP + ++ Q LQ+ Q P Q
Sbjct: 2776 ------------------------TP-EHLIKMQKQKLQMPPQPPPPQAQSAPPQPTA-- 2808
Query: 147 QQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFTGNKTQVIPTTVAAPTP 206
Q + QP Q+P + V AP PG + TG + Q+ + +PT
Sbjct: 2809 QVQVQTSQPPQQQSPQLTTVTAPRPGAL--LTGTTVANLQVA----RLTRVPT------- 2855
Query: 207 AQAQITATGQQQPQA-QPAQ 225
+Q+ A GQ Q QA QPAQ
Sbjct: 2856 --SQLQAQGQMQTQAPQPAQ 2873
Score = 38.5 bits (88), Expect = 0.009
Identities = 58/220 (26%), Positives = 79/220 (35%), Gaps = 46/220 (20%)
Query: 26 QLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIVPDSK 85
Q LL+++QQ QQ+ Q AQ V Q+ QQ+ P +QQ
Sbjct: 2927 QQLLKLKQQAVQQQKAIQP----QAAQGPAAVQQKITAQQITTPGAQQKV---------- 2972
Query: 86 LIQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQLLQVVRAANGAQYIFQPQQSVVL 145
A A L TP+ Q + GAQ + Q Q V
Sbjct: 2973 -----------AYAAQPALKTQFLTTPISQ-----------AQKLAGAQQV-QTQIQVAK 3009
Query: 146 QQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFTGNKTQVIPTTVAAPT 205
QV+ Q P IQQV A SPQT + Q G + Q+IP A
Sbjct: 3010 LPQVVQQQTP----VASIQQV-ASASQQASPQTVALTQATA---AGQQVQMIPAVTATAQ 3061
Query: 206 PAQAQITATGQQQPQAQPAQTQ-APLVLQVDGTGDTSSEE 244
Q ++ + P QT AP QV + D+ S++
Sbjct: 3062 VVQQKLIQQQVVTTASAPLQTPGAPNPAQVPASSDSPSQQ 3101
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 53.1 bits (126), Expect = 3e-07
Identities = 41/158 (25%), Positives = 73/158 (46%), Gaps = 12/158 (7%)
Query: 142 SVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFTGNKTQVIPTTV 201
SVV+ + +P + P + P SP +P+++ +P
Sbjct: 787 SVVIVPEGLPPLPPPPPSGATPPPIAPTGPPTASPPVPAKEEPEELPAAPGP---LPPPP 843
Query: 202 AAPTPAQAQITATGQQQPQAQPAQTQA---PLVLQVDGTG---DTSSEEDEDEEEDYDDD 255
P P +T PQ P T P L+ D T ++S EE+E+EEE+ +++
Sbjct: 844 PPPPPVPGPVTLP---PPQLVPEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEE 900
Query: 256 EEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTE 293
EEE++E++ E+ + +EE E++ +EE +E F+ E
Sbjct: 901 EEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEE 938
Score = 43.1 bits (100), Expect = 3e-04
Identities = 28/98 (28%), Positives = 49/98 (50%), Gaps = 12/98 (12%)
Query: 197 IPTTVAAPTPAQAQITATGQQQPQAQPAQTQAPLVLQVDGTGDTSSEEDEDE-------E 249
+P V P P Q+ G PA + V+ ++ + + EE+E+E E
Sbjct: 849 VPGPVTLPPP---QLVPEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEE 905
Query: 250 EDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQ 287
E+ D +EEE+ E++ E+ + EEE E++ +EEG+
Sbjct: 906 EEEDFEEEEEDEEEYFEEEEEEEEEF--EEEFEEEEGE 941
Score = 41.6 bits (96), Expect = 0.001
Identities = 22/55 (40%), Positives = 38/55 (69%), Gaps = 5/55 (9%)
Query: 243 EEDEDEEEDY----DDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTE 293
EE+E++EE+Y +++EEE +E+ E+G++EEE ED+ +EE +E+ D E
Sbjct: 911 EEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEE-EEEDEEEEEELEEVEDLE 964
Score = 30.8 bits (68), Expect = 1.8
Identities = 13/35 (37%), Positives = 23/35 (65%)
Query: 238 GDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEE 272
G+ EE+E++EE+ ++ EE + + G G+VEE
Sbjct: 940 GELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEE 974
Score = 28.9 bits (63), Expect = 6.8
Identities = 15/46 (32%), Positives = 29/46 (63%), Gaps = 7/46 (15%)
Query: 239 DTSSEEDEDEEEDYDDDE---EEDKEKDGAEDGQVEEEPLNSEDDV 281
+ EE+E+ EE+++++E EE++E++ E EEE L +D+
Sbjct: 922 EEEEEEEEEFEEEFEEEEGELEEEEEEEDEE----EEEELEEVEDL 963
>gi|166064029 angiomotin isoform 1 [Homo sapiens]
Length = 1084
Score = 53.1 bits (126), Expect = 3e-07
Identities = 25/52 (48%), Positives = 31/52 (59%), Gaps = 1/52 (1%)
Query: 31 VQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIVP 82
+ QQ Q QQQQHHHHHHHQQ Q QQ Q + + P +Q ++A VP
Sbjct: 374 LSQQQQQQQQQHHHHHHHQQQQQQQPQQQPGEAYSAM-PRAQPSSASYQPVP 424
Score = 37.7 bits (86), Expect = 0.015
Identities = 45/175 (25%), Positives = 60/175 (34%), Gaps = 27/175 (15%)
Query: 69 PASQQATAPQVIVPDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNS-------G 121
P + ATA + + + M A+ A A AA A A +P T + G
Sbjct: 886 PVAAAATAAAITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAG 945
Query: 122 QLLQVVRAANGAQYIFQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVI 181
Q+ A+ A P + QV P APV L P+P + Q
Sbjct: 946 QIPAAASVASAAAVA--PSAAAAAAVQVAP-----AAPAPVPAPALVPVPAPAAAQASAP 998
Query: 182 IQPQQILFTGNKTQVIPTTV--AAPTPAQAQITATGQQQPQAQPAQTQAPLVLQV 234
Q Q PT+ APTPA A Q + A PA P L +
Sbjct: 999 AQTQA-----------PTSAPAVAPTPAPTPTPAVAQAEVPASPATGPGPHRLSI 1042
>gi|17975763 myelin transcription factor 1 [Homo sapiens]
Length = 1121
Score = 52.8 bits (125), Expect = 4e-07
Identities = 26/72 (36%), Positives = 44/72 (61%)
Query: 238 GDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTENVVV 297
G S EE+++EEE+ +++EEED+E++ E+ + EEE E++ +EE +E + V+
Sbjct: 253 GILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVI 312
Query: 298 CQYDKIHRSKNK 309
Q D H S K
Sbjct: 313 FQEDTSHTSAQK 324
>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
Length = 1184
Score = 52.8 bits (125), Expect = 4e-07
Identities = 32/92 (34%), Positives = 49/92 (53%), Gaps = 13/92 (14%)
Query: 214 TGQQQPQAQPAQTQAPLVLQVD-----------GTGDTSS-EEDEDEEEDYDDDEEEDKE 261
T +QPQ +PA + P ++ D GT D EEDE EE D+DE D++
Sbjct: 63 TQDKQPQ-EPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDED 121
Query: 262 KDGAEDGQVEEEPLNSEDDVSDEEGQELFDTE 293
++ E + EEE + ED+ DE+G+++ D E
Sbjct: 122 EEDEEGDREEEEEIEEEDEDDDEDGEDVEDEE 153
Score = 40.4 bits (93), Expect = 0.002
Identities = 21/53 (39%), Positives = 32/53 (60%), Gaps = 1/53 (1%)
Query: 236 GTGDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQE 288
G D EE + EEE+ ++E+ED ++DG ED + EEE E++ +EE E
Sbjct: 118 GDEDEEDEEGDREEEEEIEEEDEDDDEDG-EDVEDEEEEEEEEEEEEEEEENE 169
Score = 40.4 bits (93), Expect = 0.002
Identities = 21/62 (33%), Positives = 36/62 (58%), Gaps = 3/62 (4%)
Query: 235 DGTGDTSSEED---EDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFD 291
D GD EE+ EDE++D D ++ ED+E++ E+ + EEE N + ++ + + D
Sbjct: 124 DEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQD 183
Query: 292 TE 293
TE
Sbjct: 184 TE 185
Score = 39.3 bits (90), Expect = 0.005
Identities = 25/74 (33%), Positives = 45/74 (60%), Gaps = 5/74 (6%)
Query: 239 DTSSEED-EDEEEDYDDDEE-EDKEKDGAEDGQ-VEEEPLNSEDDVSDEEGQELFDTENV 295
D +ED EDEE D +++EE E++++D EDG+ VE+E E++ +EE +E + ++
Sbjct: 115 DEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEE--NEDHQ 172
Query: 296 VVCQYDKIHRSKNK 309
+ C +I + K
Sbjct: 173 MNCHNTRIMQDTEK 186
Score = 35.0 bits (79), Expect = 0.095
Identities = 17/55 (30%), Positives = 30/55 (54%), Gaps = 2/55 (3%)
Query: 235 DGTGDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQEL 289
D + E+E+E E+ D+D++ED E ED + EEE E++ + E ++
Sbjct: 121 DEEDEEGDREEEEEIEEEDEDDDEDGE--DVEDEEEEEEEEEEEEEEEENEDHQM 173
Score = 34.3 bits (77), Expect = 0.16
Identities = 17/86 (19%), Positives = 42/86 (48%), Gaps = 1/86 (1%)
Query: 215 GQQQPQAQPAQTQAPLVLQVDGTGDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVE-EE 273
G + + + + ++ + D ED ++EE+ +++EEE++E++ ED Q+
Sbjct: 118 GDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHN 177
Query: 274 PLNSEDDVSDEEGQELFDTENVVVCQ 299
+D D+ + +D + +V +
Sbjct: 178 TRIMQDTEKDDNNNDEYDNYDELVAK 203
Score = 34.3 bits (77), Expect = 0.16
Identities = 16/65 (24%), Positives = 35/65 (53%)
Query: 239 DTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTENVVVC 298
+ E+D+++ ED +D+EEE++E++ E+ + E+ + + + E D N
Sbjct: 136 EEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYD 195
Query: 299 QYDKI 303
YD++
Sbjct: 196 NYDEL 200
>gi|20336260 retinoblastoma protein-binding zinc finger protein
isoform b [Homo sapiens]
Length = 1682
Score = 52.4 bits (124), Expect = 6e-07
Identities = 33/148 (22%), Positives = 66/148 (44%), Gaps = 12/148 (8%)
Query: 145 LQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFTGNKTQVIPTTVAAP 204
+Q + +P A + P P + QP + + Q +P +A P
Sbjct: 185 IQDIQLKTSEPDFTSANMRDSAEGPKEDEEKPSASALEQPATLQEVAS--QEVPPELATP 242
Query: 205 TPAQAQITATGQQQPQAQPAQTQAPLVLQVDGTGDTSSEEDEDEEEDYDDDEEEDKEKDG 264
PA +PQ +P + +V+ G+ EE+E++EE+ +DD++++ E +G
Sbjct: 243 APAW---------EPQPEPDERLEAAACEVNDLGEEEEEEEEEDEEEEEDDDDDELEDEG 293
Query: 265 AEDGQVEEEPLNSEDDV-SDEEGQELFD 291
E+ + E E ++ DE+ ++L +
Sbjct: 294 EEEASMPNENSVKEPEIRCDEKPEDLLE 321
>gi|20336258 retinoblastoma protein-binding zinc finger protein
isoform a [Homo sapiens]
Length = 1718
Score = 52.4 bits (124), Expect = 6e-07
Identities = 33/148 (22%), Positives = 66/148 (44%), Gaps = 12/148 (8%)
Query: 145 LQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFTGNKTQVIPTTVAAP 204
+Q + +P A + P P + QP + + Q +P +A P
Sbjct: 185 IQDIQLKTSEPDFTSANMRDSAEGPKEDEEKPSASALEQPATLQEVAS--QEVPPELATP 242
Query: 205 TPAQAQITATGQQQPQAQPAQTQAPLVLQVDGTGDTSSEEDEDEEEDYDDDEEEDKEKDG 264
PA +PQ +P + +V+ G+ EE+E++EE+ +DD++++ E +G
Sbjct: 243 APAW---------EPQPEPDERLEAAACEVNDLGEEEEEEEEEDEEEEEDDDDDELEDEG 293
Query: 265 AEDGQVEEEPLNSEDDV-SDEEGQELFD 291
E+ + E E ++ DE+ ++L +
Sbjct: 294 EEEASMPNENSVKEPEIRCDEKPEDLLE 321
>gi|55953110 retinoblastoma protein-binding zinc finger protein
isoform c [Homo sapiens]
Length = 1481
Score = 52.0 bits (123), Expect = 8e-07
Identities = 26/99 (26%), Positives = 53/99 (53%), Gaps = 10/99 (10%)
Query: 194 TQVIPTTVAAPTPAQAQITATGQQQPQAQPAQTQAPLVLQVDGTGDTSSEEDEDEEEDYD 253
+Q +P +A P PA +PQ +P + +V+ G+ EE+E++EE+ +
Sbjct: 31 SQEVPPELATPAPAW---------EPQPEPDERLEAAACEVNDLGEEEEEEEEEDEEEEE 81
Query: 254 DDEEEDKEKDGAEDGQVEEEPLNSEDDV-SDEEGQELFD 291
DD++++ E +G E+ + E E ++ DE+ ++L +
Sbjct: 82 DDDDDELEDEGEEEASMPNENSVKEPEIRCDEKPEDLLE 120
>gi|56549668 AT rich interactive domain 2 (ARID, RFX-like) [Homo
sapiens]
Length = 1835
Score = 51.6 bits (122), Expect = 1e-06
Identities = 78/260 (30%), Positives = 102/260 (39%), Gaps = 33/260 (12%)
Query: 28 LLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIVPDSKLI 87
+L V++Q QQQQH QQ Q Q PQQ Q Q + P A Q +S LI
Sbjct: 1006 MLSVKRQ---QQQQHSPAPPPQQVQVQVQQPQQVQMQ--VQPQQSNAGVGQPASGESSLI 1060
Query: 88 QHMNASNMSAAATAATLALPA-GVTPVQQILTNSGQLLQVVRAANGAQYIFQ----PQQS 142
+ + + L LPA + P S Q++ V + A + Q QQ
Sbjct: 1061 KQLLLPKRGPSTPGGKLILPAPQIPPPNNARAPSPQVVYQVASNQAAGFGVQGQTPAQQL 1120
Query: 143 VVLQQ--QVIPQMQP--GGVQAPVIQQVLAPLPGG-ISPQTGVIIQPQQILFTGNKT--Q 195
+V QQ Q++P P GGVQ I L LPG IS I Q +GN+
Sbjct: 1121 LVGQQNVQLVPSAMPPSGGVQTVPISN-LQILPGPLISNSPATIFQGT----SGNQVTIT 1175
Query: 196 VIPTTVAAPTP----------AQAQITATGQQQPQAQPAQTQAPLVLQVDGTGD-TSSEE 244
V+P T AP A A IT +G Q P QT G T++
Sbjct: 1176 VVPNTSFAPATVSQGNATQLIAPAGITMSGTQTGVGLPVQTLPATQASPAGQSSCTTATP 1235
Query: 245 DEDEEEDYDDDEEEDKEKDG 264
++ EEE KE G
Sbjct: 1236 PFKGDKIICQKEEEAKEATG 1255
Score = 36.6 bits (83), Expect = 0.033
Identities = 50/197 (25%), Positives = 69/197 (35%), Gaps = 32/197 (16%)
Query: 56 TVPQQAQTQQVLIPASQQATAPQVIVPD-------SKLIQHMNASNMSAAA----TAATL 104
T PQ QT A Q+ +I P S ++ + N A T A +
Sbjct: 824 TSPQPVQTSSQQTSAGSQSQDTVIIAPPQYVTTSASNIVSATSVQNFQVATGQMVTIAGV 883
Query: 105 ALPAGVTPVQQILTNSGQLLQVVRAANGAQYIFQPQQSVVLQQQVIPQMQP---GGVQAP 161
P Q + Q V + Q I QPQQ QQ V+ QP G AP
Sbjct: 884 PSPQASRVGFQNIAPKPLPSQQVSSTVVQQPIQQPQQPT--QQSVVIVSQPAQQGQTYAP 941
Query: 162 VIQQVL----APLPGGISPQTGVIIQPQQILFTGNKTQVIPTTVAAPTPAQAQITATGQQ 217
I Q++ A LP G Q + TG + + P++ +P PA T
Sbjct: 942 AIHQIVLANPAALPAG-----------QTVQLTG-QPNITPSSSPSPVPATNNQVPTAMS 989
Query: 218 QPQAQPAQTQAPLVLQV 234
+Q P V Q+
Sbjct: 990 SSSTPQSQGPPPTVSQM 1006
>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
Length = 748
Score = 51.2 bits (121), Expect = 1e-06
Identities = 61/228 (26%), Positives = 84/228 (36%), Gaps = 20/228 (8%)
Query: 8 ENKLMQSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHH---HHHHQQAQPQQTVPQQAQTQ 64
+ + Q +A ++ Q ++Q QQQ Q QQQQ H HH Q Q QQ Q +
Sbjct: 183 QQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIA 242
Query: 65 QVLIPASQQATAPQVIVPDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQLL 124
Q+ + QQ Q Q + A + P Q L Q L
Sbjct: 243 QLQLQQQQQQQQQQ---------QQQQQQALQAQPPIQQPPMQQPQPPPSQALP---QQL 290
Query: 125 QVVRAANGAQYIFQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGI---SPQTGVI 181
Q + Q QPQQ V Q Q Q+ P P++ Q A LPG + P +
Sbjct: 291 QQMHHTQHHQPPPQPQQPPVAQNQP-SQLPPQSQTQPLVSQAQA-LPGQMLYTQPPLKFV 348
Query: 182 IQPQQILFTGNKTQVIPTTVAAPTPAQAQITATGQQQPQAQPAQTQAP 229
P + + QV A T AQ+ A G Q Q+ +P
Sbjct: 349 RAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSP 396
Score = 47.4 bits (111), Expect = 2e-05
Identities = 75/303 (24%), Positives = 111/303 (36%), Gaps = 58/303 (19%)
Query: 2 ELKTLWENKLMQSRAVDGFHSEEQQLLLQVQ--------QQHQP-------QQQQHHHHH 46
+L+ + + +L Q + ++QQ LQ Q QQ QP QQ Q HH
Sbjct: 237 QLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHT 296
Query: 47 HHQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIVPDSKLIQHMNASNMSAAATAATLAL 106
H Q PQ P AQ Q +P Q T P L+ A T L
Sbjct: 297 QHHQPPPQPQQPPVAQNQPSQLPPQSQ-TQP--------LVSQAQALPGQMLYTQPPLKF 347
Query: 107 PAGVTPVQQ--ILTNSGQLLQVVRAANGAQYIFQPQQSVVLQQQVIPQMQPGGVQAPVIQ 164
VQQ + Q V+ A AQ + V + Q +P + V
Sbjct: 348 VRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMV---APGVQVSQSSLPMLSSPSPGQQVQT 404
Query: 165 QVLAPLPGGISPQTG-VIIQPQQILFTG---NKTQVIPTTVAAPTPAQAQITATGQQQPQ 220
P P SPQ G QP + +G + + +P+ +P P+Q+ +TA + PQ
Sbjct: 405 PQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPS--PSPQPSQSPVTA---RTPQ 459
Query: 221 AQPAQTQAPLVLQVDGTGDTS-SEEDEDEEEDYDD-------------------DEEEDK 260
+ PL V+ + S + + EE+ Y D D+ ED+
Sbjct: 460 NFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQYLDKLKQLSKYIEPLRRMINKIDKNEDR 519
Query: 261 EKD 263
+KD
Sbjct: 520 KKD 522
Score = 47.0 bits (110), Expect = 2e-05
Identities = 65/211 (30%), Positives = 78/211 (36%), Gaps = 33/211 (15%)
Query: 26 QLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATAP--QVIVPD 83
Q LQ+QQ QQQQ QQA QQ QQ Q QQ A Q A Q +V
Sbjct: 150 QTQLQLQQVALQQQQQQQQFQQQQQAALQQ---QQQQQQQQQFQAQQSAMQQQFQAVVQQ 206
Query: 84 SKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQLLQVVRAANGAQYIFQPQQSV 143
+ +Q + QQI QL ++ + Q Q QQ
Sbjct: 207 QQQLQQQQQQQQH--------LIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQ--QQQQQQ 256
Query: 144 VLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFTGNKTQVIPTTVAA 203
QQQ Q QP +Q P +QQ P P PQ Q QQ+ T +
Sbjct: 257 QQQQQQALQAQP-PIQQPPMQQPQPP-PSQALPQ-----QLQQMHHTQHH---------- 299
Query: 204 PTPAQAQITATGQQQPQAQPAQTQA-PLVLQ 233
P Q Q Q QP P Q+Q PLV Q
Sbjct: 300 QPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQ 330
>gi|4507379 TATA box binding protein [Homo sapiens]
Length = 339
Score = 50.4 bits (119), Expect = 2e-06
Identities = 37/97 (38%), Positives = 49/97 (50%), Gaps = 3/97 (3%)
Query: 23 EEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPAS-QQATAPQVIV 81
EEQQ Q QQQ Q QQQQ QQ Q QQ QQ Q QQ + A+ QQ+T+ Q
Sbjct: 53 EEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQ 112
Query: 82 PDS-KLIQHMNASNMSAAATAATLAL-PAGVTPVQQI 116
S + Q ++ ++ A T L P+ +TP+ I
Sbjct: 113 GTSGQAPQLFHSQTLTTAPLPGTTPLYPSPMTPMTPI 149
>gi|38787935 BMP-2 inducible kinase isoform a [Homo sapiens]
Length = 1161
Score = 49.7 bits (117), Expect = 4e-06
Identities = 23/43 (53%), Positives = 25/43 (58%)
Query: 23 EEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQ 65
++QQ Q QQQ Q QQQQHHHHHHH Q Q TQQ
Sbjct: 468 QQQQQQQQQQQQQQQQQQQHHHHHHHHLLQDAYMQQYQHATQQ 510
Score = 47.8 bits (112), Expect = 1e-05
Identities = 28/57 (49%), Positives = 32/57 (56%), Gaps = 6/57 (10%)
Query: 23 EEQQLLLQVQQQHQPQQQQHHHHHHH--QQAQPQQ----TVPQQAQTQQVLIPASQQ 73
++QQ Q QQQ Q QQQ HHHHHHH Q A QQ T QQ QQ L+ + Q
Sbjct: 469 QQQQQQQQQQQQQQQQQQHHHHHHHHLLQDAYMQQYQHATQQQQMLQQQFLMHSVYQ 525
Score = 38.9 bits (89), Expect = 0.007
Identities = 38/143 (26%), Positives = 57/143 (39%), Gaps = 20/143 (13%)
Query: 23 EEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATA-----P 77
++ ++L Q+QQ QQ H H H Q Q QQ QQ Q QQ QQ
Sbjct: 433 QQHRVLQQLQQGDWRLQQLHLQHRHPHQQQQQQQQQQQQQQQQQQQQQQQQQQQHHHHHH 492
Query: 78 QVIVPDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQLLQVVRAANGAQYIF 137
++ D+ + Q+ +A+ QQ L +S + Q +A+ +
Sbjct: 493 HHLLQDAYMQQYQHATQQQQMLQ-------------QQFLMHS--VYQPQPSASQYPTMM 537
Query: 138 QPQQSVVLQQQVIPQMQPGGVQA 160
Q QQQ++ Q QP QA
Sbjct: 538 PQYQQAFFQQQMLAQHQPSQQQA 560
Score = 33.9 bits (76), Expect = 0.21
Identities = 19/76 (25%), Positives = 34/76 (44%)
Query: 218 QPQAQPAQTQAPLVLQVDGTGDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNS 277
Q Q Q ++ + D SSEE+E ++E+ E+ D D E + PL
Sbjct: 730 QGQVQKGNDESESDFESDPPSPKSSEEEEQDDEEVLQGEQGDFNDDDTEPENLGHRPLLM 789
Query: 278 EDDVSDEEGQELFDTE 293
+ + +EE + D++
Sbjct: 790 DSEDEEEEEKHSSDSD 805
>gi|38787904 BMP-2 inducible kinase isoform b [Homo sapiens]
Length = 662
Score = 49.7 bits (117), Expect = 4e-06
Identities = 23/43 (53%), Positives = 25/43 (58%)
Query: 23 EEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQ 65
++QQ Q QQQ Q QQQQHHHHHHH Q Q TQQ
Sbjct: 468 QQQQQQQQQQQQQQQQQQQHHHHHHHHLLQDAYMQQYQHATQQ 510
Score = 47.8 bits (112), Expect = 1e-05
Identities = 28/57 (49%), Positives = 32/57 (56%), Gaps = 6/57 (10%)
Query: 23 EEQQLLLQVQQQHQPQQQQHHHHHHH--QQAQPQQ----TVPQQAQTQQVLIPASQQ 73
++QQ Q QQQ Q QQQ HHHHHHH Q A QQ T QQ QQ L+ + Q
Sbjct: 469 QQQQQQQQQQQQQQQQQQHHHHHHHHLLQDAYMQQYQHATQQQQMLQQQFLMHSVYQ 525
Score = 38.9 bits (89), Expect = 0.007
Identities = 38/143 (26%), Positives = 57/143 (39%), Gaps = 20/143 (13%)
Query: 23 EEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATA-----P 77
++ ++L Q+QQ QQ H H H Q Q QQ QQ Q QQ QQ
Sbjct: 433 QQHRVLQQLQQGDWRLQQLHLQHRHPHQQQQQQQQQQQQQQQQQQQQQQQQQQQHHHHHH 492
Query: 78 QVIVPDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQLLQVVRAANGAQYIF 137
++ D+ + Q+ +A+ QQ L +S + Q +A+ +
Sbjct: 493 HHLLQDAYMQQYQHATQQQQMLQ-------------QQFLMHS--VYQPQPSASQYPTMM 537
Query: 138 QPQQSVVLQQQVIPQMQPGGVQA 160
Q QQQ++ Q QP QA
Sbjct: 538 PQYQQAFFQQQMLAQHQPSQQQA 560
>gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]
Length = 788
Score = 49.7 bits (117), Expect = 4e-06
Identities = 64/232 (27%), Positives = 86/232 (37%), Gaps = 33/232 (14%)
Query: 8 ENKLMQSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHH---HHHHQQAQPQQTVPQQAQTQ 64
+ + Q +A ++ Q ++Q QQQ Q QQQQ H HH Q Q QQ Q +
Sbjct: 183 QQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIA 242
Query: 65 QVLIPASQQATAPQVIVPDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQLL 124
Q+ + QQ Q Q + A + P Q L Q L
Sbjct: 243 QLQLQQQQQQQQQQ---------QQQQQQALQAQPPIQQPPMQQPQPPPSQALP---QQL 290
Query: 125 QVVRAANGAQYIFQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQP 184
Q + Q QPQQ V Q Q Q+ P P++ Q A LPG
Sbjct: 291 QQMHHTQHHQPPPQPQQPPVAQNQP-SQLPPQSQTQPLVSQAQA-LPG------------ 336
Query: 185 QQILFTGNKTQVI--PTTVAAPTPAQAQITATGQQQPQAQPAQTQAPLVLQV 234
Q+L+T + + P V P P Q Q+ AQ AQ AP V +
Sbjct: 337 -QMLYTQPPLKFVRAPMVVQQP-PVQPQVQQQQTAVQTAQAAQMVAPGVQMI 386
Score = 47.0 bits (110), Expect = 2e-05
Identities = 65/211 (30%), Positives = 78/211 (36%), Gaps = 33/211 (15%)
Query: 26 QLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATAP--QVIVPD 83
Q LQ+QQ QQQQ QQA QQ QQ Q QQ A Q A Q +V
Sbjct: 150 QTQLQLQQVALQQQQQQQQFQQQQQAALQQ---QQQQQQQQQFQAQQSAMQQQFQAVVQQ 206
Query: 84 SKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQLLQVVRAANGAQYIFQPQQSV 143
+ +Q + QQI QL ++ + Q Q QQ
Sbjct: 207 QQQLQQQQQQQQH--------LIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQ--QQQQQQ 256
Query: 144 VLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFTGNKTQVIPTTVAA 203
QQQ Q QP +Q P +QQ P P PQ Q QQ+ T +
Sbjct: 257 QQQQQQALQAQP-PIQQPPMQQPQPP-PSQALPQ-----QLQQMHHTQHH---------- 299
Query: 204 PTPAQAQITATGQQQPQAQPAQTQA-PLVLQ 233
P Q Q Q QP P Q+Q PLV Q
Sbjct: 300 QPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQ 330
Score = 45.1 bits (105), Expect = 9e-05
Identities = 75/332 (22%), Positives = 114/332 (34%), Gaps = 76/332 (22%)
Query: 2 ELKTLWENKLMQSRAVDGFHSEEQQLLLQVQ--------QQHQP-------QQQQHHHHH 46
+L+ + + +L Q + ++QQ LQ Q QQ QP QQ Q HH
Sbjct: 237 QLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHT 296
Query: 47 HHQQAQPQQTVPQQAQTQQVLIPASQQ------------------------ATAPQVIVP 82
H Q PQ P AQ Q +P Q AP V+
Sbjct: 297 QHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQ 356
Query: 83 DSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQLLQ-------VVRAANGAQY 135
Q A AA + P GV + + L G ++ V A +
Sbjct: 357 PPVQPQVQQQQTAVQTAQAAQMVAP-GVQMITEALAQGGMHIRARFPPTTAVSAIPSSSI 415
Query: 136 IFQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTG-VIIQPQQILFTG--- 191
Q + Q +P + V P P SPQ G QP + +G
Sbjct: 416 PLGRQPMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAP 475
Query: 192 NKTQVIPTTVAAPTPAQAQITATGQQQPQAQPAQTQAPLVLQVDGTGDTS-SEEDEDEEE 250
+ + +P+ +P P+Q+ +TA + PQ + PL V+ + S + + EE+
Sbjct: 476 SPSSFLPS--PSPQPSQSPVTA---RTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQ 530
Query: 251 DYDD-------------------DEEEDKEKD 263
Y D D+ ED++KD
Sbjct: 531 QYLDKLKQLSKYIEPLRRMINKIDKNEDRKKD 562
>gi|17017963 forkhead box P2 isoform I [Homo sapiens]
Length = 715
Score = 48.9 bits (115), Expect = 6e-06
Identities = 46/152 (30%), Positives = 60/152 (39%), Gaps = 28/152 (18%)
Query: 11 LMQSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPA 70
L Q + + + +++QL LQ+ QQ Q QQQQ QQ Q QQ QQ Q QQ
Sbjct: 130 LQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ----- 184
Query: 71 SQQATAPQVIVPDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQLLQVVRAA 130
QQ Q +K Q AA Q L QLLQ+
Sbjct: 185 -QQQQQQQHPGKQAKEQQQQQQQQQQLAA---------------QQLVFQQQLLQM---- 224
Query: 131 NGAQYIFQPQQSVVLQQQVIPQMQPGGVQAPV 162
Q + Q Q + LQ+Q + + PG PV
Sbjct: 225 ---QQLQQQQHLLSLQRQGLISIPPGQAALPV 253
Score = 40.8 bits (94), Expect = 0.002
Identities = 36/119 (30%), Positives = 56/119 (47%), Gaps = 11/119 (9%)
Query: 1 MELKTLWENKLMQSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHHHHH-HQQAQPQQTVPQ 59
+ L+ L + + Q + ++QQ Q QQQ Q QQQQ H +QA+ QQ Q
Sbjct: 146 LHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQ---Q 202
Query: 60 QAQTQQVLIPASQQATAPQVIVPDSKLIQHMNASNMSAAATAATLALPAG--VTPVQQI 116
Q Q QQ L A+QQ Q ++ +L Q + ++ +++P G PVQ +
Sbjct: 203 QQQQQQQL--AAQQLVFQQQLLQMQQLQQQQHLLSLQ---RQGLISIPPGQAALPVQSL 256
>gi|22538413 forkhead box P2 isoform III [Homo sapiens]
Length = 623
Score = 48.9 bits (115), Expect = 6e-06
Identities = 46/152 (30%), Positives = 60/152 (39%), Gaps = 28/152 (18%)
Query: 11 LMQSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPA 70
L Q + + + +++QL LQ+ QQ Q QQQQ QQ Q QQ QQ Q QQ
Sbjct: 38 LQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ----- 92
Query: 71 SQQATAPQVIVPDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQLLQVVRAA 130
QQ Q +K Q AA Q L QLLQ+
Sbjct: 93 -QQQQQQQHPGKQAKEQQQQQQQQQQLAA---------------QQLVFQQQLLQM---- 132
Query: 131 NGAQYIFQPQQSVVLQQQVIPQMQPGGVQAPV 162
Q + Q Q + LQ+Q + + PG PV
Sbjct: 133 ---QQLQQQQHLLSLQRQGLISIPPGQAALPV 161
Score = 40.8 bits (94), Expect = 0.002
Identities = 36/119 (30%), Positives = 56/119 (47%), Gaps = 11/119 (9%)
Query: 1 MELKTLWENKLMQSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHHHHH-HQQAQPQQTVPQ 59
+ L+ L + + Q + ++QQ Q QQQ Q QQQQ H +QA+ QQ Q
Sbjct: 54 LHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQ---Q 110
Query: 60 QAQTQQVLIPASQQATAPQVIVPDSKLIQHMNASNMSAAATAATLALPAG--VTPVQQI 116
Q Q QQ L A+QQ Q ++ +L Q + ++ +++P G PVQ +
Sbjct: 111 QQQQQQQL--AAQQLVFQQQLLQMQQLQQQQHLLSLQ---RQGLISIPPGQAALPVQSL 164
>gi|149999352 forkhead box P2 isoform II [Homo sapiens]
Length = 740
Score = 48.9 bits (115), Expect = 6e-06
Identities = 46/152 (30%), Positives = 60/152 (39%), Gaps = 28/152 (18%)
Query: 11 LMQSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPA 70
L Q + + + +++QL LQ+ QQ Q QQQQ QQ Q QQ QQ Q QQ
Sbjct: 155 LQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ----- 209
Query: 71 SQQATAPQVIVPDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQLLQVVRAA 130
QQ Q +K Q AA Q L QLLQ+
Sbjct: 210 -QQQQQQQHPGKQAKEQQQQQQQQQQLAA---------------QQLVFQQQLLQM---- 249
Query: 131 NGAQYIFQPQQSVVLQQQVIPQMQPGGVQAPV 162
Q + Q Q + LQ+Q + + PG PV
Sbjct: 250 ---QQLQQQQHLLSLQRQGLISIPPGQAALPV 278
Score = 40.8 bits (94), Expect = 0.002
Identities = 36/119 (30%), Positives = 56/119 (47%), Gaps = 11/119 (9%)
Query: 1 MELKTLWENKLMQSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHHHHH-HQQAQPQQTVPQ 59
+ L+ L + + Q + ++QQ Q QQQ Q QQQQ H +QA+ QQ Q
Sbjct: 171 LHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQ---Q 227
Query: 60 QAQTQQVLIPASQQATAPQVIVPDSKLIQHMNASNMSAAATAATLALPAG--VTPVQQI 116
Q Q QQ L A+QQ Q ++ +L Q + ++ +++P G PVQ +
Sbjct: 228 QQQQQQQL--AAQQLVFQQQLLQMQQLQQQQHLLSLQ---RQGLISIPPGQAALPVQSL 281
Score = 37.4 bits (85), Expect = 0.019
Identities = 37/118 (31%), Positives = 54/118 (45%), Gaps = 18/118 (15%)
Query: 47 HHQQAQPQQTVPQ---QAQTQQVLIPASQQATAP-QVIVPDSKLIQHMNAS------NMS 96
H QQ Q Q Q Q QT + P S P Q ++P++KL ++S N
Sbjct: 51 HLQQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQELLPETKLCICGHSSGDGHPHNTF 110
Query: 97 AAATAATLALPAGVTP--VQQILTNSGQLLQVVRAANGAQYIFQPQQSVVLQQQVIPQ 152
A + + P +TP +QQIL Q V + Q + Q QQ+V+LQQQ + +
Sbjct: 111 AVPVSVAMMTPQVITPQQMQQILQ------QQVLSPQQLQALLQQQQAVMLQQQQLQE 162
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 48.9 bits (115), Expect = 6e-06
Identities = 37/133 (27%), Positives = 60/133 (45%), Gaps = 24/133 (18%)
Query: 180 VIIQPQQ---ILFTGNKTQVIPTTVAAPTPAQAQIT------------ATGQQQPQAQPA 224
V++ P + + K V P AA TPA+ +T AT + A P
Sbjct: 64 VVVSPTKKVAVATPAKKAAVTPGKKAAATPAKKTVTPAKAVTTPGKKGATPGKALVATPG 123
Query: 225 QTQAPLVLQVDGTG------DTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVE---EEPL 275
+ A + + G D+ EED+D EED +DDE+ED+++D E ++ P
Sbjct: 124 KKGAAIPAKGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPA 183
Query: 276 NSEDDVSDEEGQE 288
+ ++D D+E E
Sbjct: 184 SEDEDDEDDEDDE 196
Score = 47.0 bits (110), Expect = 2e-05
Identities = 31/111 (27%), Positives = 56/111 (50%), Gaps = 5/111 (4%)
Query: 216 QQQPQAQPAQ-TQAPLVLQVDGTGDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEP 274
++ + PA+ +A V+ V E++E+++ED DDD++ED E D ED + EEE
Sbjct: 208 EEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEE 267
Query: 275 LNSEDDVSDEEG---QELFDTENVVVCQYDKIHRSKNKWKFHLKDGIMNLN 322
E+ V + G +E+ + + K+ ++ F+L G +N N
Sbjct: 268 -EEEEPVKEAPGKRKKEMAKQKAAPEAKKQKVEGTEPTTAFNLFVGNLNFN 317
Score = 40.4 bits (93), Expect = 0.002
Identities = 31/142 (21%), Positives = 55/142 (38%), Gaps = 5/142 (3%)
Query: 149 VIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFTGNKTQVIPTTVAAPTPAQ 208
V+ + V P + + P + + P + + T K P TP +
Sbjct: 65 VVSPTKKVAVATPAKKAAVTPGKKAAATPAKKTVTPAKAVTTPGKKGATPGKALVATPGK 124
Query: 209 --AQITATGQQQPQAQPAQTQAPLVLQVDGTGDTSSEEDEDEEEDYDDDEEEDKEKDGAE 266
A I A G + + + + D + E+DEDE+ED D+ E + A
Sbjct: 125 KGAAIPAKGAKNGKNAKKEDSDE---EEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAA 181
Query: 267 DGQVEEEPLNSEDDVSDEEGQE 288
+E+ + EDD D++ +E
Sbjct: 182 PASEDEDDEDDEDDEDDDDDEE 203
Score = 39.7 bits (91), Expect = 0.004
Identities = 25/94 (26%), Positives = 42/94 (44%), Gaps = 29/94 (30%)
Query: 218 QPQAQPAQTQAPLVLQVDGTGDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEP--- 274
+P A A AP + EDED+E+D DD++++D E+D +E+ +E P
Sbjct: 171 EPAAMKAAAAAP------------ASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKG 218
Query: 275 --------------LNSEDDVSDEEGQELFDTEN 294
ED+ D+E ++ D E+
Sbjct: 219 KKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDED 252
Score = 39.7 bits (91), Expect = 0.004
Identities = 25/115 (21%), Positives = 58/115 (50%), Gaps = 6/115 (5%)
Query: 213 ATGQQQPQAQPAQTQAPLVLQVDGTGDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEE 272
A G++ + P + + + + D ++D+DE+++ DDDE++++E++ E+ V+E
Sbjct: 216 AKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKE 275
Query: 273 EPLNSEDDVSDEEG------QELFDTENVVVCQYDKIHRSKNKWKFHLKDGIMNL 321
P + +++ ++ Q++ TE + + NK LK GI ++
Sbjct: 276 APGKRKKEMAKQKAAPEAKKQKVEGTEPTTAFNLFVGNLNFNKSAPELKTGISDV 330
Score = 34.7 bits (78), Expect = 0.12
Identities = 25/102 (24%), Positives = 39/102 (38%), Gaps = 23/102 (22%)
Query: 210 QITATGQQQPQAQPAQTQAPLVLQVDGTGDTSSEEDEDEEEDY----------------- 252
+I + A PA D D EED+ EEE
Sbjct: 169 EIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVK 228
Query: 253 ------DDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQE 288
D+DEEED E + +D + +E+ + +D+ +EE +E
Sbjct: 229 AKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEE 270
>gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens]
Length = 4374
Score = 48.9 bits (115), Expect = 6e-06
Identities = 23/73 (31%), Positives = 42/73 (57%), Gaps = 5/73 (6%)
Query: 239 DTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQ-----ELFDTE 293
D S +E+E+EEED +DD+E+D+ ++G ED + + ++D D E FD E
Sbjct: 2429 DDSQDEEEEEEEDEEDDQEDDEGEEGDEDDDDDGSEMELDEDYPDMNASPLVRFERFDRE 2488
Query: 294 NVVVCQYDKIHRS 306
+ ++ ++D + S
Sbjct: 2489 DDLIIEFDNMFSS 2501
Score = 41.2 bits (95), Expect = 0.001
Identities = 24/86 (27%), Positives = 43/86 (50%), Gaps = 9/86 (10%)
Query: 211 ITATGQQQPQAQPAQTQAPLVLQVDGTGDTSSE--------EDEDEEEDYDDDEEEDKEK 262
++ +G+ + Q +AP L T + E EDE+E +D ++++
Sbjct: 2369 VSRSGEDESQEDVLMDEAPSNLSQASTLQANREDSMNILDPEDEEEHTQEEDSSGSNEDE 2428
Query: 263 DGAEDGQVEEEPLNSEDDVSDEEGQE 288
D ++D + EEE + EDD D+EG+E
Sbjct: 2429 DDSQDEEEEEEE-DEEDDQEDDEGEE 2453
>gi|21735415 centromere protein B [Homo sapiens]
Length = 599
Score = 48.1 bits (113), Expect = 1e-05
Identities = 55/242 (22%), Positives = 102/242 (42%), Gaps = 23/242 (9%)
Query: 69 PASQQATAPQVIVPDSK-------LIQHMNASNMSAAATAATLALPAGVTPVQQILTNSG 121
P + QA P +SK L +++ A + AA + + L AG Q + T+
Sbjct: 250 PRAGQAGLPCDYTANSKGGVTTQALAKYLKALDTRMAAESRRVLLLAGRLAAQSLDTSGL 309
Query: 122 QLLQVVRAANGAQYIFQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVI 181
+ +Q+ F P L++ V+ Q++ G + ++ + +A L G P +
Sbjct: 310 RHVQLA--------FFPPGTVHPLERGVVQQVK-GHYRQAMLLKAMAALEGQ-DPSGLQL 359
Query: 182 IQPQQILFTGNKTQVIPTTVAAPTPAQA------QITATGQQQPQAQPAQTQAPLVLQVD 235
+ + F Q + + A +A T T + + + + + + +
Sbjct: 360 GLTEALHFVAAAWQAVEPSDIAACFREAGFGGGPNATITTSLKSEGEEEEEEEEEEEEEE 419
Query: 236 GTGDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTENV 295
G G+ EE E+EEE+ + EE +E++ E+G V+ + ED+ S EG E D
Sbjct: 420 GEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQG 479
Query: 296 VV 297
VV
Sbjct: 480 VV 481
Score = 43.5 bits (101), Expect = 3e-04
Identities = 22/62 (35%), Positives = 36/62 (58%), Gaps = 2/62 (3%)
Query: 207 AQAQITATGQQQPQAQPAQTQAPLVLQVDG--TGDTSSEEDEDEEEDYDDDEEEDKEKDG 264
AQ + A G + Q P + ++G D+ SEE++DEEED +D++++D E+DG
Sbjct: 477 AQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDG 536
Query: 265 AE 266
E
Sbjct: 537 DE 538
>gi|156071452 nardilysin isoform b [Homo sapiens]
Length = 1151
Score = 48.1 bits (113), Expect = 1e-05
Identities = 23/57 (40%), Positives = 36/57 (63%), Gaps = 1/57 (1%)
Query: 238 GDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTEN 294
G T + D++EEE+ +++EE+D E GAE +EE + ED+ DE +L DTE+
Sbjct: 135 GKTGNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDL-DTED 190
Score = 39.3 bits (90), Expect = 0.005
Identities = 23/57 (40%), Positives = 29/57 (50%)
Query: 237 TGDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTE 293
T D EE E+EEED D+D + E D E E+E + DD D E EL + E
Sbjct: 141 TDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEELE 197
Score = 34.7 bits (78), Expect = 0.12
Identities = 16/41 (39%), Positives = 26/41 (63%), Gaps = 3/41 (7%)
Query: 235 DGTGDTSSEEDEDEEEDYDDDEEEDKEKD---GAEDGQVEE 272
D D+ +E ++D+EE +DD++E D E D ED ++EE
Sbjct: 155 DDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEE 195
>gi|156071450 nardilysin isoform a [Homo sapiens]
Length = 1219
Score = 48.1 bits (113), Expect = 1e-05
Identities = 23/57 (40%), Positives = 36/57 (63%), Gaps = 1/57 (1%)
Query: 238 GDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTEN 294
G T + D++EEE+ +++EE+D E GAE +EE + ED+ DE +L DTE+
Sbjct: 135 GKTGNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDL-DTED 190
Score = 39.3 bits (90), Expect = 0.005
Identities = 23/57 (40%), Positives = 29/57 (50%)
Query: 237 TGDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTE 293
T D EE E+EEED D+D + E D E E+E + DD D E EL + E
Sbjct: 141 TDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEELE 197
Score = 36.6 bits (83), Expect = 0.033
Identities = 20/58 (34%), Positives = 32/58 (55%), Gaps = 3/58 (5%)
Query: 235 DGTGDTSSEEDEDEEEDYDDDEEEDKEKD---GAEDGQVEEEPLNSEDDVSDEEGQEL 289
D D+ +E ++D+EE +DD++E D E D ED ++EE +E E Q+L
Sbjct: 155 DDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEERAEARKKTTEKQQL 212
Score = 30.4 bits (67), Expect = 2.3
Identities = 13/52 (25%), Positives = 28/52 (53%)
Query: 239 DTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELF 290
+ EE D+E+++DD+ ++D + + E ++EE + ++ Q LF
Sbjct: 165 EDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEERAEARKKTTEKQQLQSLF 216
>gi|62953127 polyhomeotic 1-like [Homo sapiens]
Length = 1004
Score = 48.1 bits (113), Expect = 1e-05
Identities = 68/256 (26%), Positives = 96/256 (37%), Gaps = 25/256 (9%)
Query: 24 EQQLLLQVQQQHQPQQQQHHHHHHH-----QQAQPQQTVPQQAQTQQVLIPASQQATAPQ 78
+QQ+ + QQQ Q +Q Q H H QQ Q QQ QQ Q Q + A Q P
Sbjct: 396 QQQIAIHHQQQFQHRQSQLLHTATHLQLAQQQQQQQQQQQQQQQPQATTLTAPQPPQVPP 455
Query: 79 V-IVPDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQLLQVVRAAN-GAQYI 136
VP S+ Q + ++ L+LP P I S + ++ GA +
Sbjct: 456 TQQVPPSQSQQQAQTLVVQPMLQSSPLSLPPDAAPKPPIPIQSKPPVAPIKPPQLGAAKM 515
Query: 137 FQPQQSVV-LQQQVIPQMQPGGVQAPV--IQQVLAP------LPGGI-SPQTGVIIQPQQ 186
QQ + QV+ QPG QA + Q+ A +PG + S Q + P
Sbjct: 516 SAAQQPPPHIPVQVVGTRQPGTAQAQALGLAQLAAAVPTSRGMPGTVQSGQAHLASSPPS 575
Query: 187 ILFTGNKTQVIPT----TVAAPTPAQAQITATGQQQPQAQPAQTQAPLVLQ---VDGTGD 239
G + PT AP A + G AQ A +Q + G
Sbjct: 576 SQAPGALQECPPTLAPGMTLAPVQGTAHVVKGGATTSSPVVAQVPAAFYMQSVHLPGKPQ 635
Query: 240 T-SSEEDEDEEEDYDD 254
T + + D EE+ DD
Sbjct: 636 TLAVKRKADSEEERDD 651
Score = 42.7 bits (99), Expect = 5e-04
Identities = 48/192 (25%), Positives = 78/192 (40%), Gaps = 30/192 (15%)
Query: 63 TQQVLIP----ASQQATAPQVIVP----DSKLIQHMNASNMSAAATAATL------ALPA 108
+Q +L+P A+ Q P P D+ +Q++ N A+A + A+P
Sbjct: 173 SQLILMPNGAVAAVQQEVPSAQSPGVHADADQVQNLAVRNQQASAQGPQMQGSTQKAIPP 232
Query: 109 GVTPVQQILTNSGQLLQVVRAANGAQYIFQPQQSVVLQQ-------QVIPQMQPGG---V 158
G +PV + S Q L V +A++GA QS+ L Q + M PGG
Sbjct: 233 GASPVSSLSQASSQALAVAQASSGA-----TNQSLNLSQAGGGSGNSIPGSMGPGGGGQA 287
Query: 159 QAPVIQQVLAPLPGGISPQTGV-IIQPQQILFTGNKTQVIPTTVAAPTPAQAQITATGQQ 217
+ Q + + GG P+ G ++QP T +Q T + +A+ +GQQ
Sbjct: 288 HGGLGQLPSSGMGGGSCPRKGTGVVQPLPAAQTVTVSQGSQTEAESAAAKKAEADGSGQQ 347
Query: 218 QPQAQPAQTQAP 229
+T P
Sbjct: 348 NVGMNLTRTATP 359
Score = 40.8 bits (94), Expect = 0.002
Identities = 60/238 (25%), Positives = 86/238 (36%), Gaps = 17/238 (7%)
Query: 13 QSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQ 72
Q A FH Q L Q H Q +QA T Q QT +
Sbjct: 46 QPNAAQYFHQFMLQQQLSNAQLHSLAAVQQATIAASRQASSPNTSTTQQQTTTTQASINL 105
Query: 73 QATAPQVIVPDSKLIQHMNASNMSAAATAA-TLALPAGVTPVQQIL-TNSGQLLQVVRAA 130
T+ ++ S+ + +A+ ++ + T + P + Q L G LLQV R
Sbjct: 106 ATTSAAQLISRSQSVSSPSATTLTQSVLLGNTTSPPLNQSQAQMYLRPQLGNLLQVNRTL 165
Query: 131 N-----GAQYIFQPQQSVVLQQQVIPQMQPGGVQAPVIQ-QVLAPLPGGISPQTGVIIQP 184
+Q I P +V QQ +P Q GV A Q Q LA + Q P
Sbjct: 166 GRNVPLASQLILMPNGAVAAVQQEVPSAQSPGVHADADQVQNLA-----VRNQQASAQGP 220
Query: 185 QQILFTGNKTQVIPTTVAAPTPAQAQITATGQQQPQAQPAQTQAPLVLQVDGTGDTSS 242
Q G+ + IP A+P + +Q ++ QA T L L G G +S
Sbjct: 221 Q---MQGSTQKAIPPG-ASPVSSLSQASSQALAVAQASSGATNQSLNLSQAGGGSGNS 274
>gi|157743257 POU domain, class 6, transcription factor 2 [Homo
sapiens]
Length = 691
Score = 47.4 bits (111), Expect = 2e-05
Identities = 58/224 (25%), Positives = 81/224 (36%), Gaps = 22/224 (9%)
Query: 11 LMQSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQ------ 64
L +A +S+ QQL LQ+QQQ Q QQQQ +Q QP P Q+Q Q
Sbjct: 166 LQNLQATSSLNSQLQQLQLQLQQQQQ-QQQQQPPPSTNQHPQPAPQAPSQSQQQPLQPTP 224
Query: 65 -QVLIPASQQATAPQVIVPDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNSGQL 123
Q PASQQ AP + + Q + S + + P + + L
Sbjct: 225 PQQPPPASQQPPAPTSQLQQAPQPQQHQPHSHSQNQNQPSPTQQSSSPPQKPSQSPGHGL 284
Query: 124 LQVVRAANGAQYIFQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQ 183
+ N Q + P S Q + L+ L G TG ++
Sbjct: 285 PSPLTPPNPLQLVNNPLAS---QAAAAAAAMSSIASSQAFGNALSSLQG----VTGQLV- 336
Query: 184 PQQILFTGNKTQVIPTTVAAPTPAQAQITATGQQQPQAQPAQTQ 227
T + Q+I T P P + A+G Q Q QP Q
Sbjct: 337 ------TNAQGQIIGTIPLMPNPGPSSQAASGTQGLQVQPITPQ 374
Score = 33.1 bits (74), Expect = 0.36
Identities = 52/192 (27%), Positives = 69/192 (35%), Gaps = 32/192 (16%)
Query: 50 QAQPQQTVPQQAQTQQVLIPASQQATAPQVIVP------DSKLIQHMNASNMSAAATAAT 103
Q Q QT P Q L+ A Q A+A ++P + ++ N +
Sbjct: 79 QHQASQTHPPFPVGPQPLLTAQQLASAVAGVMPGGPPALNQPILIPFNMAGQLGGQQGLV 138
Query: 104 LALP-AGVTPVQQILTNSGQ------LLQVVRAANGAQYIFQPQQSVVLQQQVIPQMQPG 156
L LP A +T +Q ++ + LQ ++A + Q Q + QQQ Q QP
Sbjct: 139 LTLPTANLTNIQGLVAAAAAGGIMTLPLQNLQATSSLNSQLQQLQLQLQQQQQQQQQQP- 197
Query: 157 GVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFTGNKTQVIPTTVAAPTPAQAQITA-TG 215
P Q P P S QP Q PT P PA Q A T
Sbjct: 198 ---PPSTNQHPQPAPQAPSQSQQ---QPLQ-----------PTPPQQPPPASQQPPAPTS 240
Query: 216 QQQPQAQPAQTQ 227
Q Q QP Q Q
Sbjct: 241 QLQQAPQPQQHQ 252
Score = 30.0 bits (66), Expect = 3.1
Identities = 53/208 (25%), Positives = 67/208 (32%), Gaps = 35/208 (16%)
Query: 34 QHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIVP---------DS 84
QHQ Q H QP T Q A ++P A +++P
Sbjct: 79 QHQASQT---HPPFPVGPQPLLTAQQLASAVAGVMPGGPPALNQPILIPFNMAGQLGGQQ 135
Query: 85 KLIQHMNASNMS-------AAATAATLALPAGVTPVQQILTNSGQLLQVVRAANGAQYIF 137
L+ + +N++ AAA + LP L + Q LQ+ Q
Sbjct: 136 GLVLTLPTANLTNIQGLVAAAAAGGIMTLPLQNLQATSSLNSQLQQLQLQLQQQQQQQQQ 195
Query: 138 QPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFTGNKTQVI 197
QP S Q PQ P Q QQ L P P PQ Q T Q
Sbjct: 196 QPPPSTNQHPQPAPQ-APSQSQ----QQPLQPTP----PQQPPPASQQPPAPTSQLQQ-- 244
Query: 198 PTTVAAPTPAQAQITATGQQQPQAQPAQ 225
AP P Q Q + Q Q Q P Q
Sbjct: 245 -----APQPQQHQPHSHSQNQNQPSPTQ 267
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.126 0.356
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,095,392
Number of Sequences: 37866
Number of extensions: 793844
Number of successful extensions: 25747
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 730
Number of HSP's successfully gapped in prelim test: 514
Number of HSP's that attempted gapping in prelim test: 8137
Number of HSP's gapped (non-prelim): 8658
length of query: 337
length of database: 18,247,518
effective HSP length: 103
effective length of query: 234
effective length of database: 14,347,320
effective search space: 3357272880
effective search space used: 3357272880
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.