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Search of human proteins with 41872631
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|41872631 fatty acid synthase [Homo sapiens]
(2511 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|41872631 fatty acid synthase [Homo sapiens] 5012 0.0
gi|8923559 3-oxoacyl-ACP synthase, mitochondrial isoform 1 precu... 107 2e-22
gi|22538446 tumor protein p53 inducible protein 3 [Homo sapiens] 106 3e-22
gi|22538444 tumor protein p53 inducible protein 3 [Homo sapiens] 106 3e-22
gi|194239674 crystallin, zeta isoform a [Homo sapiens] 86 4e-16
gi|13236495 crystallin, zeta isoform a [Homo sapiens] 86 4e-16
gi|24308257 vesicle amine transport protein 1 homolog (T. califo... 70 3e-11
gi|28557745 zinc binding alcohol dehydrogenase domain containing... 69 6e-11
gi|197927207 crystallin, zeta isoform c [Homo sapiens] 69 8e-11
gi|75991709 lymphocyte antigen 9 isoform b [Homo sapiens] 65 6e-10
gi|18379349 vesicle amine transport protein 1 [Homo sapiens] 65 8e-10
gi|194239676 crystallin, zeta isoform b [Homo sapiens] 58 1e-07
gi|239755236 PREDICTED: similar to Putative uncharacterized prot... 57 2e-07
gi|239749764 PREDICTED: hypothetical protein XP_002347152 [Homo ... 57 2e-07
gi|239744023 PREDICTED: hypothetical protein XP_002343020 [Homo ... 57 2e-07
gi|223972627 3-oxoacyl-ACP synthase, mitochondrial isoform 2 pre... 57 3e-07
gi|90669511 crystallin, zeta-like 1 [Homo sapiens] 52 6e-06
gi|67078406 trans-2-enoyl-CoA reductase, mitochondrial isoform b... 52 1e-05
gi|67078404 trans-2-enoyl-CoA reductase, mitochondrial isoform a... 52 1e-05
gi|226059159 prostaglandin reductase 1 isoform 1 [Homo sapiens] 49 6e-05
gi|226059133 prostaglandin reductase 1 isoform 1 [Homo sapiens] 49 6e-05
gi|51243059 mitochondrial malonyltransferase isoform a precursor... 49 8e-05
gi|226056130 prostaglandin reductase 1 isoform 2 [Homo sapiens] 48 1e-04
gi|4501929 class I alcohol dehydrogenase, alpha subunit [Homo sa... 39 0.064
gi|4501933 class I alcohol dehydrogenase, gamma subunit [Homo sa... 39 0.084
gi|71565152 class II alcohol dehydrogenase, pi subunit [Homo sap... 38 0.11
gi|34577061 class I alcohol dehydrogenase, beta subunit [Homo sa... 37 0.19
gi|4504505 hydroxysteroid (17-beta) dehydrogenase 4 [Homo sapiens] 35 0.93
gi|194097330 hexokinase 3 [Homo sapiens] 34 1.6
gi|156523966 class V alcohol dehydrogenase isoform 1 [Homo sapiens] 33 2.7
>gi|41872631 fatty acid synthase [Homo sapiens]
Length = 2511
Score = 5012 bits (13001), Expect = 0.0
Identities = 2511/2511 (100%), Positives = 2511/2511 (100%)
Query: 1 MEEVVIAGMSGKLPESENLQEFWDNLIGGVDMVTDDDRRWKAGLYGLPRRSGKLKDLSRF 60
MEEVVIAGMSGKLPESENLQEFWDNLIGGVDMVTDDDRRWKAGLYGLPRRSGKLKDLSRF
Sbjct: 1 MEEVVIAGMSGKLPESENLQEFWDNLIGGVDMVTDDDRRWKAGLYGLPRRSGKLKDLSRF 60
Query: 61 DASFFGVHPKQAHTMDPQLRLLLEVTYEAIVDGGINPDSLRGTHTGVWVGVSGSETSEAL 120
DASFFGVHPKQAHTMDPQLRLLLEVTYEAIVDGGINPDSLRGTHTGVWVGVSGSETSEAL
Sbjct: 61 DASFFGVHPKQAHTMDPQLRLLLEVTYEAIVDGGINPDSLRGTHTGVWVGVSGSETSEAL 120
Query: 121 SRDPETLVGYSMVGCQRAMMANRLSFFFDFRGPSIALDTACSSSLMALQNAYQAIHSGQC 180
SRDPETLVGYSMVGCQRAMMANRLSFFFDFRGPSIALDTACSSSLMALQNAYQAIHSGQC
Sbjct: 121 SRDPETLVGYSMVGCQRAMMANRLSFFFDFRGPSIALDTACSSSLMALQNAYQAIHSGQC 180
Query: 181 PAAIVGGINVLLKPNTSVQFLRLGMLSPEGTCKAFDTAGNGYCRSEGVVAVLLTKKSLAR 240
PAAIVGGINVLLKPNTSVQFLRLGMLSPEGTCKAFDTAGNGYCRSEGVVAVLLTKKSLAR
Sbjct: 181 PAAIVGGINVLLKPNTSVQFLRLGMLSPEGTCKAFDTAGNGYCRSEGVVAVLLTKKSLAR 240
Query: 241 RVYATILNAGTNTDGFKEQGVTFPSGDIQEQLIRSLYQSAGVAPESFEYIEAHGTGTKVG 300
RVYATILNAGTNTDGFKEQGVTFPSGDIQEQLIRSLYQSAGVAPESFEYIEAHGTGTKVG
Sbjct: 241 RVYATILNAGTNTDGFKEQGVTFPSGDIQEQLIRSLYQSAGVAPESFEYIEAHGTGTKVG 300
Query: 301 DPQELNGITRALCATRQEPLLIGSTKSNMGHPEPASGLAALAKVLLSLEHGLWAPNLHFH 360
DPQELNGITRALCATRQEPLLIGSTKSNMGHPEPASGLAALAKVLLSLEHGLWAPNLHFH
Sbjct: 301 DPQELNGITRALCATRQEPLLIGSTKSNMGHPEPASGLAALAKVLLSLEHGLWAPNLHFH 360
Query: 361 SPNPEIPALLDGRLQVVDQPLPVRGGNVGINSFGFGGSNVHIILRPNTQPPPAPAPHATL 420
SPNPEIPALLDGRLQVVDQPLPVRGGNVGINSFGFGGSNVHIILRPNTQPPPAPAPHATL
Sbjct: 361 SPNPEIPALLDGRLQVVDQPLPVRGGNVGINSFGFGGSNVHIILRPNTQPPPAPAPHATL 420
Query: 421 PRLLRASGRTPEAVQKLLEQGLRHSQDLAFLSMLNDIAAVPATAMPFRGYAVLGGERGGP 480
PRLLRASGRTPEAVQKLLEQGLRHSQDLAFLSMLNDIAAVPATAMPFRGYAVLGGERGGP
Sbjct: 421 PRLLRASGRTPEAVQKLLEQGLRHSQDLAFLSMLNDIAAVPATAMPFRGYAVLGGERGGP 480
Query: 481 EVQQVPAGERPLWFICSGMGTQWRGMGLSLMRLDRFRDSILRSDEAVKPFGLKVSQLLLS 540
EVQQVPAGERPLWFICSGMGTQWRGMGLSLMRLDRFRDSILRSDEAVKPFGLKVSQLLLS
Sbjct: 481 EVQQVPAGERPLWFICSGMGTQWRGMGLSLMRLDRFRDSILRSDEAVKPFGLKVSQLLLS 540
Query: 541 TDESTFDDIVHSFVSLTAIQIGLIDLLSCMGLRPDGIVGHSLGEVACGYADGCLSQEEAV 600
TDESTFDDIVHSFVSLTAIQIGLIDLLSCMGLRPDGIVGHSLGEVACGYADGCLSQEEAV
Sbjct: 541 TDESTFDDIVHSFVSLTAIQIGLIDLLSCMGLRPDGIVGHSLGEVACGYADGCLSQEEAV 600
Query: 601 LAAYWRGQCIKEAHLPPGAMAAVGLSWEECKQRCPPGVVPACHNSKDTVTISGPQAPVFE 660
LAAYWRGQCIKEAHLPPGAMAAVGLSWEECKQRCPPGVVPACHNSKDTVTISGPQAPVFE
Sbjct: 601 LAAYWRGQCIKEAHLPPGAMAAVGLSWEECKQRCPPGVVPACHNSKDTVTISGPQAPVFE 660
Query: 661 FVEQLRKEGVFAKEVRTGGMAFHSYFMEAIAPPLLQELKKVIREPKPRSARWLSTSIPEA 720
FVEQLRKEGVFAKEVRTGGMAFHSYFMEAIAPPLLQELKKVIREPKPRSARWLSTSIPEA
Sbjct: 661 FVEQLRKEGVFAKEVRTGGMAFHSYFMEAIAPPLLQELKKVIREPKPRSARWLSTSIPEA 720
Query: 721 QWHSSLARTSSAEYNVNNLVSPVLFQEALWHVPEHAVVLEIAPHALLQAVLKRGLKPSCT 780
QWHSSLARTSSAEYNVNNLVSPVLFQEALWHVPEHAVVLEIAPHALLQAVLKRGLKPSCT
Sbjct: 721 QWHSSLARTSSAEYNVNNLVSPVLFQEALWHVPEHAVVLEIAPHALLQAVLKRGLKPSCT 780
Query: 781 IIPLMKKDHRDNLEFFLAGIGRLHLSGIDANPNALFPPVEFPAPRGTPLISPLIKWDHSL 840
IIPLMKKDHRDNLEFFLAGIGRLHLSGIDANPNALFPPVEFPAPRGTPLISPLIKWDHSL
Sbjct: 781 IIPLMKKDHRDNLEFFLAGIGRLHLSGIDANPNALFPPVEFPAPRGTPLISPLIKWDHSL 840
Query: 841 AWDVPAAEDFPNGSGSPSAAIYNIDTSSESPDHYLVDHTLDGRVLFPATGYLSIVWKTLA 900
AWDVPAAEDFPNGSGSPSAAIYNIDTSSESPDHYLVDHTLDGRVLFPATGYLSIVWKTLA
Sbjct: 841 AWDVPAAEDFPNGSGSPSAAIYNIDTSSESPDHYLVDHTLDGRVLFPATGYLSIVWKTLA 900
Query: 901 RALGLGVEQLPVVFEDVVLHQATILPKTGTVSLEVRLLEASRAFEVSENGNLVVSGKVYQ 960
RALGLGVEQLPVVFEDVVLHQATILPKTGTVSLEVRLLEASRAFEVSENGNLVVSGKVYQ
Sbjct: 901 RALGLGVEQLPVVFEDVVLHQATILPKTGTVSLEVRLLEASRAFEVSENGNLVVSGKVYQ 960
Query: 961 WDDPDPRLFDHPESPTPNPTEPLFLAQAEVYKELRLRGYDYGPHFQGILEASLEGDSGRL 1020
WDDPDPRLFDHPESPTPNPTEPLFLAQAEVYKELRLRGYDYGPHFQGILEASLEGDSGRL
Sbjct: 961 WDDPDPRLFDHPESPTPNPTEPLFLAQAEVYKELRLRGYDYGPHFQGILEASLEGDSGRL 1020
Query: 1021 LWKDNWVSFMDTMLQMSILGSAKHGLYLPTRVTAIHIDPATHRQKLYTLQDKAQVADVVV 1080
LWKDNWVSFMDTMLQMSILGSAKHGLYLPTRVTAIHIDPATHRQKLYTLQDKAQVADVVV
Sbjct: 1021 LWKDNWVSFMDTMLQMSILGSAKHGLYLPTRVTAIHIDPATHRQKLYTLQDKAQVADVVV 1080
Query: 1081 SRWLRVTVAGGVHISGLHTESAPRRQQEQQVPILEKFCFTPHTEEGCLSERAALQEELQL 1140
SRWLRVTVAGGVHISGLHTESAPRRQQEQQVPILEKFCFTPHTEEGCLSERAALQEELQL
Sbjct: 1081 SRWLRVTVAGGVHISGLHTESAPRRQQEQQVPILEKFCFTPHTEEGCLSERAALQEELQL 1140
Query: 1141 CKGLVQALQTKVTQQGLKMVVPGLDGAQIPRDPSQQELPRLLSAACRLQLNGNLQLELAQ 1200
CKGLVQALQTKVTQQGLKMVVPGLDGAQIPRDPSQQELPRLLSAACRLQLNGNLQLELAQ
Sbjct: 1141 CKGLVQALQTKVTQQGLKMVVPGLDGAQIPRDPSQQELPRLLSAACRLQLNGNLQLELAQ 1200
Query: 1201 VLAQERPKLPEDPLLSGLLDSPALKACLDTAVENMPSLKMKVVEVLAGHGHLYSRIPGLL 1260
VLAQERPKLPEDPLLSGLLDSPALKACLDTAVENMPSLKMKVVEVLAGHGHLYSRIPGLL
Sbjct: 1201 VLAQERPKLPEDPLLSGLLDSPALKACLDTAVENMPSLKMKVVEVLAGHGHLYSRIPGLL 1260
Query: 1261 SPHPLLQLSYTATDRHPQALEAAQAELQQHDVAQGQWDPADPAPSALGSADLLVCNCAVA 1320
SPHPLLQLSYTATDRHPQALEAAQAELQQHDVAQGQWDPADPAPSALGSADLLVCNCAVA
Sbjct: 1261 SPHPLLQLSYTATDRHPQALEAAQAELQQHDVAQGQWDPADPAPSALGSADLLVCNCAVA 1320
Query: 1321 ALGDPASALSNMVAALREGGFLLLHTLLRGHPLGDIVAFLTSTEPQYGQGILSQDAWESL 1380
ALGDPASALSNMVAALREGGFLLLHTLLRGHPLGDIVAFLTSTEPQYGQGILSQDAWESL
Sbjct: 1321 ALGDPASALSNMVAALREGGFLLLHTLLRGHPLGDIVAFLTSTEPQYGQGILSQDAWESL 1380
Query: 1381 FSRVSLRLVGLKKSFYGSTLFLCRRPTPQDSPIFLPVDDTSFRWVESLKGILADEDSSRP 1440
FSRVSLRLVGLKKSFYGSTLFLCRRPTPQDSPIFLPVDDTSFRWVESLKGILADEDSSRP
Sbjct: 1381 FSRVSLRLVGLKKSFYGSTLFLCRRPTPQDSPIFLPVDDTSFRWVESLKGILADEDSSRP 1440
Query: 1441 VWLKAINCATSGVVGLVNCLRREPGGNRLRCVLLSNLSSTSHVPEVDPGSAELQKVLQGD 1500
VWLKAINCATSGVVGLVNCLRREPGGNRLRCVLLSNLSSTSHVPEVDPGSAELQKVLQGD
Sbjct: 1441 VWLKAINCATSGVVGLVNCLRREPGGNRLRCVLLSNLSSTSHVPEVDPGSAELQKVLQGD 1500
Query: 1501 LVMNVYRDGAWGAFRHFLLEEDKPEEPTAHAFVSTLTRGDLSSIRWVCSSLRHAQPTCPG 1560
LVMNVYRDGAWGAFRHFLLEEDKPEEPTAHAFVSTLTRGDLSSIRWVCSSLRHAQPTCPG
Sbjct: 1501 LVMNVYRDGAWGAFRHFLLEEDKPEEPTAHAFVSTLTRGDLSSIRWVCSSLRHAQPTCPG 1560
Query: 1561 AQLCTVYYASLNFRDIMLATGKLSPDAIPGKWTSQDSLLGMEFSGRDASGKRVMGLVPAK 1620
AQLCTVYYASLNFRDIMLATGKLSPDAIPGKWTSQDSLLGMEFSGRDASGKRVMGLVPAK
Sbjct: 1561 AQLCTVYYASLNFRDIMLATGKLSPDAIPGKWTSQDSLLGMEFSGRDASGKRVMGLVPAK 1620
Query: 1621 GLATSVLLSPDFLWDVPSNWTLEEAASVPVVYSTAYYALVVRGRVRPGETLLIHSGSGGV 1680
GLATSVLLSPDFLWDVPSNWTLEEAASVPVVYSTAYYALVVRGRVRPGETLLIHSGSGGV
Sbjct: 1621 GLATSVLLSPDFLWDVPSNWTLEEAASVPVVYSTAYYALVVRGRVRPGETLLIHSGSGGV 1680
Query: 1681 GQAAIAIALSLGCRVFTTVGSAEKRAYLQARFPQLDSTSFANSRDTSFEQHVLWHTGGKG 1740
GQAAIAIALSLGCRVFTTVGSAEKRAYLQARFPQLDSTSFANSRDTSFEQHVLWHTGGKG
Sbjct: 1681 GQAAIAIALSLGCRVFTTVGSAEKRAYLQARFPQLDSTSFANSRDTSFEQHVLWHTGGKG 1740
Query: 1741 VDLVLNSLAEEKLQASVRCLATHGRFLEIGKFDLSQNHPLGMAIFLKNVTFHGVLLDAFF 1800
VDLVLNSLAEEKLQASVRCLATHGRFLEIGKFDLSQNHPLGMAIFLKNVTFHGVLLDAFF
Sbjct: 1741 VDLVLNSLAEEKLQASVRCLATHGRFLEIGKFDLSQNHPLGMAIFLKNVTFHGVLLDAFF 1800
Query: 1801 NESSADWREVWALVQAGIRDGVVRPLKCTVFHGAQVEDAFRYMAQGKHIGKVVVQVLAEE 1860
NESSADWREVWALVQAGIRDGVVRPLKCTVFHGAQVEDAFRYMAQGKHIGKVVVQVLAEE
Sbjct: 1801 NESSADWREVWALVQAGIRDGVVRPLKCTVFHGAQVEDAFRYMAQGKHIGKVVVQVLAEE 1860
Query: 1861 PEAVLKGAKPKLMSAISKTFCPAHKSYIIAGGLGGFGLELAQWLIQRGVQKLVLTSRSGI 1920
PEAVLKGAKPKLMSAISKTFCPAHKSYIIAGGLGGFGLELAQWLIQRGVQKLVLTSRSGI
Sbjct: 1861 PEAVLKGAKPKLMSAISKTFCPAHKSYIIAGGLGGFGLELAQWLIQRGVQKLVLTSRSGI 1920
Query: 1921 RTGYQAKQVRRWRRQGVQVQVSTSNISSLEGARGLIAEAAQLGPVGGVFNLAVVLRDGLL 1980
RTGYQAKQVRRWRRQGVQVQVSTSNISSLEGARGLIAEAAQLGPVGGVFNLAVVLRDGLL
Sbjct: 1921 RTGYQAKQVRRWRRQGVQVQVSTSNISSLEGARGLIAEAAQLGPVGGVFNLAVVLRDGLL 1980
Query: 1981 ENQTPEFFQDVCKPKYSGTLNLDRVTREACPELDYFVVFSSVSCGRGNAGQSNYGFANSA 2040
ENQTPEFFQDVCKPKYSGTLNLDRVTREACPELDYFVVFSSVSCGRGNAGQSNYGFANSA
Sbjct: 1981 ENQTPEFFQDVCKPKYSGTLNLDRVTREACPELDYFVVFSSVSCGRGNAGQSNYGFANSA 2040
Query: 2041 MERICEKRRHEGLPGLAVQWGAIGDVGILVETMSTNDTIVSGTLPQRMASCLEVLDLFLN 2100
MERICEKRRHEGLPGLAVQWGAIGDVGILVETMSTNDTIVSGTLPQRMASCLEVLDLFLN
Sbjct: 2041 MERICEKRRHEGLPGLAVQWGAIGDVGILVETMSTNDTIVSGTLPQRMASCLEVLDLFLN 2100
Query: 2101 QPHMVLSSFVLAEKAAAYRDRDSQRDLVEAVAHILGIRDLAAVNLDSSLADLGLDSLMSV 2160
QPHMVLSSFVLAEKAAAYRDRDSQRDLVEAVAHILGIRDLAAVNLDSSLADLGLDSLMSV
Sbjct: 2101 QPHMVLSSFVLAEKAAAYRDRDSQRDLVEAVAHILGIRDLAAVNLDSSLADLGLDSLMSV 2160
Query: 2161 EVRQTLERELNLVLSVREVRQLTLRKLQELSSKADEASELACPTPKEDGLAQQQTQLNLR 2220
EVRQTLERELNLVLSVREVRQLTLRKLQELSSKADEASELACPTPKEDGLAQQQTQLNLR
Sbjct: 2161 EVRQTLERELNLVLSVREVRQLTLRKLQELSSKADEASELACPTPKEDGLAQQQTQLNLR 2220
Query: 2221 SLLVNPEGPTLMRLNSVQSSERPLFLVHPIEGSTTVFHSLASRLSIPTYGLQCTRAAPLD 2280
SLLVNPEGPTLMRLNSVQSSERPLFLVHPIEGSTTVFHSLASRLSIPTYGLQCTRAAPLD
Sbjct: 2221 SLLVNPEGPTLMRLNSVQSSERPLFLVHPIEGSTTVFHSLASRLSIPTYGLQCTRAAPLD 2280
Query: 2281 SIHSLAAYYIDCIRQVQPEGPYRVAGYSYGACVAFEMCSQLQAQQSPAPTHNSLFLFDGS 2340
SIHSLAAYYIDCIRQVQPEGPYRVAGYSYGACVAFEMCSQLQAQQSPAPTHNSLFLFDGS
Sbjct: 2281 SIHSLAAYYIDCIRQVQPEGPYRVAGYSYGACVAFEMCSQLQAQQSPAPTHNSLFLFDGS 2340
Query: 2341 PTYVLAYTQSYRAKLTPGCEAEAETEAICFFVQQFTDMEHNRVLEALLPLKGLEERVAAA 2400
PTYVLAYTQSYRAKLTPGCEAEAETEAICFFVQQFTDMEHNRVLEALLPLKGLEERVAAA
Sbjct: 2341 PTYVLAYTQSYRAKLTPGCEAEAETEAICFFVQQFTDMEHNRVLEALLPLKGLEERVAAA 2400
Query: 2401 VDLIIKSHQGLDRQELSFAARSFYYKLRAAEQYTPKAKYHGNVMLLRAKTGGAYGEDLGA 2460
VDLIIKSHQGLDRQELSFAARSFYYKLRAAEQYTPKAKYHGNVMLLRAKTGGAYGEDLGA
Sbjct: 2401 VDLIIKSHQGLDRQELSFAARSFYYKLRAAEQYTPKAKYHGNVMLLRAKTGGAYGEDLGA 2460
Query: 2461 DYNLSQVCDGKVSVHVIEGDHRTLLEGSGLESIISIIHSSLAEPRVSVREG 2511
DYNLSQVCDGKVSVHVIEGDHRTLLEGSGLESIISIIHSSLAEPRVSVREG
Sbjct: 2461 DYNLSQVCDGKVSVHVIEGDHRTLLEGSGLESIISIIHSSLAEPRVSVREG 2511
>gi|8923559 3-oxoacyl-ACP synthase, mitochondrial isoform 1
precursor [Homo sapiens]
Length = 459
Score = 107 bits (266), Expect = 2e-22
Identities = 111/427 (25%), Positives = 177/427 (41%), Gaps = 40/427 (9%)
Query: 4 VVIAGMSGKLPESENLQEFWDNLIGG----VDMVTDDDRRWKAGLYG-LPRRSGKLKDLS 58
VVI G+ P WD LIGG V +V ++ + + +PR S D
Sbjct: 44 VVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGS----DEG 99
Query: 59 RFDASFFGVHPKQAHTMDPQLRLLLEVTYEAIVDGGINPDSLRG-THTGVWVGVSGSETS 117
+F+ F V +M + + A+ D G +P S TGV +G+ G
Sbjct: 100 QFNEQNF-VSKSDIKSMSSPTIMAIGAAELAMKDSGWHPQSEADQVATGVAIGM-GMIPL 157
Query: 118 EALSRDPETLVGYSMVGCQRA-----------MMANRLSFFFDFRGPSIALDTACSSSLM 166
E +S ET + + G + M A ++S + +GP+ A+ TAC++
Sbjct: 158 EVVS---ETALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAH 214
Query: 167 ALQNAYQAIHSGQCPAAIVGGINVLLKPNTSVQFLRLGMLS----PEGTCKAFDTAGNGY 222
A+ ++++ I G + GG + + P + F R LS P+ C+ F +G+
Sbjct: 215 AVGDSFRFIAHGDADVMVAGGTDSCISPLSLAGFSRARALSTNSDPKLACRPFHPKRDGF 274
Query: 223 CRSEGVVAVLLTKKSLA----RRVYATILNAGTNTDGFKEQGVTFPSGDIQEQLIRSLYQ 278
EG ++L + A R+YA +L G + D P G+ + + + +
Sbjct: 275 VMGEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDA-GHITAPDPEGEGALRCMAAALK 333
Query: 279 SAGVAPESFEYIEAHGTGTKVGDPQELNGITRALCATRQEPLLIGSTKSNMGHPEPASGL 338
AGV PE YI AH T T +GD E N + L L + STK GH A+G
Sbjct: 334 DAGVQPEEISYINAHATSTPLGDAAE-NKAIKHLFKDHAYALAVSSTKGATGHLLGAAGA 392
Query: 339 AALAKVLLSLEHGLWAPNLHFHSPNPEIPALLDGRLQVVDQPLPVRGGNVGI-NSFGFGG 397
A L+ + P L+ PE + + Q +G+ NSFGFGG
Sbjct: 393 VEAAFTTLACYYQKLPPTLNLDCSEPEFDL---NYVPLKAQEWKTEKRFIGLTNSFGFGG 449
Query: 398 SNVHIIL 404
+N + +
Sbjct: 450 TNATLCI 456
>gi|22538446 tumor protein p53 inducible protein 3 [Homo sapiens]
Length = 332
Score = 106 bits (264), Expect = 3e-22
Identities = 88/318 (27%), Positives = 147/318 (46%), Gaps = 36/318 (11%)
Query: 1560 GAQLCTVYYASLNFRDIMLATGKLSPDAIPGKWTSQDSLLGMEFSGRDAS---------- 1609
G L V ++LN D+M G+ P PG ++LG+E SG A
Sbjct: 28 GEVLLKVAASALNRADLMQRQGQYDPP--PGA----SNILGLEASGHVAELGPGCQGHWK 81
Query: 1610 -GKRVMGLVPAKGLATSVLLSPDFLWDVPSNWTLEEAASVPVVYSTAYYALVVRGRVRPG 1668
G M L+P G A V + L +P TL +AA++P + TA+ L + G V+ G
Sbjct: 82 IGDTAMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAG 141
Query: 1669 ETLLIHSGSGGVGQAAIAIALSLGCRVFTTVGSAEKRAYLQARFPQLDSTSFANSRDTSF 1728
+ +LIH+G GVG AAI + G T GS +K + +L + + N + F
Sbjct: 142 DYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAE----KLGAAAGFNYKKEDF 197
Query: 1729 EQHVLWHTGGKGVDLVLNSLAEEKLQASVRCLATHGRFLEIGKFDLSQNHPLGMAIFLKN 1788
+ L T G GV+L+L+ + + +V CLA GR++ G L + +F K
Sbjct: 198 SEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYG---LMGGGDINGPLFSKL 254
Query: 1789 VTFHGVLLDAFFNESSADWREVWALVQAGIR--------DGVVR--PLKCTVFHGAQVED 1838
+ G L+ + ++++ LV A +G R P+ ++ ++++
Sbjct: 255 LFKRGSLITSLLRSRDNKYKQM--LVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQE 312
Query: 1839 AFRYMAQGKHIGKVVVQV 1856
A +YM K+IGK+V+++
Sbjct: 313 AHKYMEANKNIGKIVLEL 330
>gi|22538444 tumor protein p53 inducible protein 3 [Homo sapiens]
Length = 332
Score = 106 bits (264), Expect = 3e-22
Identities = 88/318 (27%), Positives = 147/318 (46%), Gaps = 36/318 (11%)
Query: 1560 GAQLCTVYYASLNFRDIMLATGKLSPDAIPGKWTSQDSLLGMEFSGRDAS---------- 1609
G L V ++LN D+M G+ P PG ++LG+E SG A
Sbjct: 28 GEVLLKVAASALNRADLMQRQGQYDPP--PGA----SNILGLEASGHVAELGPGCQGHWK 81
Query: 1610 -GKRVMGLVPAKGLATSVLLSPDFLWDVPSNWTLEEAASVPVVYSTAYYALVVRGRVRPG 1668
G M L+P G A V + L +P TL +AA++P + TA+ L + G V+ G
Sbjct: 82 IGDTAMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAG 141
Query: 1669 ETLLIHSGSGGVGQAAIAIALSLGCRVFTTVGSAEKRAYLQARFPQLDSTSFANSRDTSF 1728
+ +LIH+G GVG AAI + G T GS +K + +L + + N + F
Sbjct: 142 DYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAE----KLGAAAGFNYKKEDF 197
Query: 1729 EQHVLWHTGGKGVDLVLNSLAEEKLQASVRCLATHGRFLEIGKFDLSQNHPLGMAIFLKN 1788
+ L T G GV+L+L+ + + +V CLA GR++ G L + +F K
Sbjct: 198 SEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYG---LMGGGDINGPLFSKL 254
Query: 1789 VTFHGVLLDAFFNESSADWREVWALVQAGIR--------DGVVR--PLKCTVFHGAQVED 1838
+ G L+ + ++++ LV A +G R P+ ++ ++++
Sbjct: 255 LFKRGSLITSLLRSRDNKYKQM--LVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQE 312
Query: 1839 AFRYMAQGKHIGKVVVQV 1856
A +YM K+IGK+V+++
Sbjct: 313 AHKYMEANKNIGKIVLEL 330
>gi|194239674 crystallin, zeta isoform a [Homo sapiens]
Length = 329
Score = 86.3 bits (212), Expect = 4e-16
Identities = 60/235 (25%), Positives = 116/235 (49%), Gaps = 10/235 (4%)
Query: 1621 GLATSVLLSPDFLWDVPSNWTLEEAASVPVVYSTAYYALVVRGRVRPGETLLIHSGSGGV 1680
G A L + ++ +P ++ A++ + Y TAY AL+ V+ GE++L+H SGGV
Sbjct: 102 GYAEYALAADHTVYKLPEKLDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGASGGV 161
Query: 1681 GQAAIAIALSLGCRVFTTVGSAEKRAYLQARFPQLDSTSFANSRDTSFEQHVLWHTGGKG 1740
G AA IA + G ++ T G+ E + + Q + N R+ ++ + + G KG
Sbjct: 162 GLAACQIARAYGLKILGTAGTEEGQKIVL----QNGAHEVFNHREVNYIDKIKKYVGEKG 217
Query: 1741 VDLVLNSLAEEKLQASVRCLATHGRFLEIGKFDLSQNHPLGMAIFLKNVTFHGVLLDAFF 1800
+D+++ LA L + L+ GR + +G + +P K + GV L F
Sbjct: 218 IDIIIEMLANVNLSKDLSLLSHGGRVIVVGSRGTIEINP--RDTMAKESSIIGVTL---F 272
Query: 1801 NESSADWREVWALVQAGIRDGVVRPLKCTVFHGAQVEDAFRYMAQGK-HIGKVVV 1854
+ + ++++ A +QAG+ G ++P+ + + +V +A + G GK+++
Sbjct: 273 SSTKEEFQQYAAALQAGMEIGWLKPVIGSQYPLEKVAEAHENIIHGSGATGKMIL 327
>gi|13236495 crystallin, zeta isoform a [Homo sapiens]
Length = 329
Score = 86.3 bits (212), Expect = 4e-16
Identities = 60/235 (25%), Positives = 116/235 (49%), Gaps = 10/235 (4%)
Query: 1621 GLATSVLLSPDFLWDVPSNWTLEEAASVPVVYSTAYYALVVRGRVRPGETLLIHSGSGGV 1680
G A L + ++ +P ++ A++ + Y TAY AL+ V+ GE++L+H SGGV
Sbjct: 102 GYAEYALAADHTVYKLPEKLDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGASGGV 161
Query: 1681 GQAAIAIALSLGCRVFTTVGSAEKRAYLQARFPQLDSTSFANSRDTSFEQHVLWHTGGKG 1740
G AA IA + G ++ T G+ E + + Q + N R+ ++ + + G KG
Sbjct: 162 GLAACQIARAYGLKILGTAGTEEGQKIVL----QNGAHEVFNHREVNYIDKIKKYVGEKG 217
Query: 1741 VDLVLNSLAEEKLQASVRCLATHGRFLEIGKFDLSQNHPLGMAIFLKNVTFHGVLLDAFF 1800
+D+++ LA L + L+ GR + +G + +P K + GV L F
Sbjct: 218 IDIIIEMLANVNLSKDLSLLSHGGRVIVVGSRGTIEINP--RDTMAKESSIIGVTL---F 272
Query: 1801 NESSADWREVWALVQAGIRDGVVRPLKCTVFHGAQVEDAFRYMAQGK-HIGKVVV 1854
+ + ++++ A +QAG+ G ++P+ + + +V +A + G GK+++
Sbjct: 273 SSTKEEFQQYAAALQAGMEIGWLKPVIGSQYPLEKVAEAHENIIHGSGATGKMIL 327
>gi|24308257 vesicle amine transport protein 1 homolog (T.
californica)-like [Homo sapiens]
Length = 419
Score = 69.7 bits (169), Expect = 3e-11
Identities = 66/249 (26%), Positives = 103/249 (41%), Gaps = 26/249 (10%)
Query: 1552 RHAQPTCPGAQL-CTVYYASLNFRDIMLATGKLS----PDAIPGKWTSQ------DSLLG 1600
R A P +L V LNF D+M+ G + +PG S DS+ G
Sbjct: 60 RKAMPEPQDGELKIRVKACGLNFIDLMVRQGNIDNPPKTPLVPGFECSGIVEALGDSVKG 119
Query: 1601 MEFSGRDASGKRVMGLVPAKGLATSVLLSPDFLWDVPSNWTLEEAASVPVVYSTAYYALV 1660
E G RVM V A V +F++ +P + + EAA+ P+ + TAY L
Sbjct: 120 YEI------GDRVMAFVNYNAWAEVVCTPVEFVYKIPDDMSFSEAAAFPMNFVTAYVMLF 173
Query: 1661 VRGRVRPGETLLIHSGSGGVGQAAIAIALSL-GCRVFTTVGSAEKRAYLQARFPQLDSTS 1719
+R G ++L+HS GGVGQA + ++ VF T + + A DS +
Sbjct: 174 EVANLREGMSVLVHSAGGGVGQAVAQLCSTVPNVTVFGTASTFKHEAI-------KDSVT 226
Query: 1720 FANSRDTSFEQHVLWHTGGKGVDLVLNSLAEEKLQASVRCLATHGRFLEIGKFDLSQNHP 1779
R+ + Q V +GVD+VL+ L + + L G ++ G ++
Sbjct: 227 HLFDRNADYVQEVK-RISAEGVDIVLDCLCGDNTGKGLSLLKPLGTYILYGSSNMVTGET 285
Query: 1780 LGMAIFLKN 1788
F K+
Sbjct: 286 KSFFSFAKS 294
>gi|28557745 zinc binding alcohol dehydrogenase domain containing 2
[Homo sapiens]
Length = 377
Score = 68.9 bits (167), Expect = 6e-11
Identities = 79/319 (24%), Positives = 130/319 (40%), Gaps = 50/319 (15%)
Query: 1568 YASLNFRDIMLATGKLSPDAIPG-----KWTSQDSLLGMEFSGRDASGKRVMGLVPAKGL 1622
+ +N DI + G+ P P + + LG+ S R G+ V + P
Sbjct: 71 FVGVNASDINYSAGRYDPSVKPPFDIGFEGIGEVVALGLSASARYTVGQAVAYMAPGS-F 129
Query: 1623 ATSVLLSPDFLWDVPSNWTLEEAASVPVVYSTAYYALVVRGRVRPGETLLIHSGSGGVGQ 1682
A ++ VPS E ++ V +TAY +L G + G+ +L+ + +GG GQ
Sbjct: 130 AEYTVVPASIATPVPS--VKPEYLTLLVSGTTAYISLKELGGLSEGKKVLVTAAAGGTGQ 187
Query: 1683 AAIAIALSLGCRVFTTVGSAEKRAYLQARFPQLDSTSFANSRDTSFEQH----VLWHTGG 1738
A+ ++ C V T S EK A+L+ S R +++ VL
Sbjct: 188 FAMQLSKKAKCHVIGTCSSDEKSAFLK---------SLGCDRPINYKTEPVGTVLKQEYP 238
Query: 1739 KGVDLVLNSLAEEKLQASVRCLATHGRFLEIGKFDLSQNHPLGMA----------IFLKN 1788
+GVD+V S+ +V LAT GR + IG F P G++ + K+
Sbjct: 239 EGVDVVYESVGGAMFDLAVDALATKGRLIVIG-FISGYQTPTGLSPVKAGTLPAKLLKKS 297
Query: 1789 VTFHGVLLDAFFNESSADWREVWALVQAGIRDGVVRPLKCTVFHG--------AQVEDAF 1840
+ G L+ + ++ A + + +G L C V G +E F
Sbjct: 298 ASVQGFFLNHYLSKYQAAMSHLLEMCVSG-------DLVCEVDLGDLSPEGRFTGLESIF 350
Query: 1841 R---YMAQGKHIGKVVVQV 1856
R YM GK+ GK+VV++
Sbjct: 351 RAVNYMYMGKNTGKIVVEL 369
>gi|197927207 crystallin, zeta isoform c [Homo sapiens]
Length = 192
Score = 68.6 bits (166), Expect = 8e-11
Identities = 49/191 (25%), Positives = 95/191 (49%), Gaps = 10/191 (5%)
Query: 1665 VRPGETLLIHSGSGGVGQAAIAIALSLGCRVFTTVGSAEKRAYLQARFPQLDSTSFANSR 1724
V+ GE++L+H SGGVG AA IA + G ++ T G+ E + + Q + N R
Sbjct: 9 VKAGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEEGQKIVL----QNGAHEVFNHR 64
Query: 1725 DTSFEQHVLWHTGGKGVDLVLNSLAEEKLQASVRCLATHGRFLEIGKFDLSQNHPLGMAI 1784
+ ++ + + G KG+D+++ LA L + L+ GR + +G + +P
Sbjct: 65 EVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSHGGRVIVVGSRGTIEINP--RDT 122
Query: 1785 FLKNVTFHGVLLDAFFNESSADWREVWALVQAGIRDGVVRPLKCTVFHGAQVEDAFRYMA 1844
K + GV L F+ + ++++ A +QAG+ G ++P+ + + +V +A +
Sbjct: 123 MAKESSIIGVTL---FSSTKEEFQQYAAALQAGMEIGWLKPVIGSQYPLEKVAEAHENII 179
Query: 1845 QGK-HIGKVVV 1854
G GK+++
Sbjct: 180 HGSGATGKMIL 190
>gi|75991709 lymphocyte antigen 9 isoform b [Homo sapiens]
Length = 193
Score = 65.5 bits (158), Expect = 6e-10
Identities = 35/41 (85%), Positives = 37/41 (90%), Gaps = 4/41 (9%)
Query: 2471 KVSVHVIEGDHRTLLEGSGLESIISIIHSSLAEPRVSVREG 2511
K+SVHVIEGDHRTLLEGSGLESII S+LAEPRVSVREG
Sbjct: 157 KLSVHVIEGDHRTLLEGSGLESII----STLAEPRVSVREG 193
>gi|18379349 vesicle amine transport protein 1 [Homo sapiens]
Length = 393
Score = 65.1 bits (157), Expect = 8e-10
Identities = 87/332 (26%), Positives = 137/332 (41%), Gaps = 42/332 (12%)
Query: 1552 RHAQPTCPGAQLCTVYYAS--LNFRDIMLATG---KLSPDAI-PG-KWTSQDSLLGMEFS 1604
R A P PG T+ + LNF D+M G +L P + PG + +G S
Sbjct: 67 RPAAPPAPGPGQLTLRLRACGLNFADLMARQGLYDRLPPLPVTPGMEGAGVVIAVGEGVS 126
Query: 1605 GRDASGKRVMGLVPAKGLATSVLLSPDFLWDVPSNWTLEEAASVPVVYSTAYYALVVRGR 1664
R A G RVM L + V + + +P T EEAA++ V Y TAY L G
Sbjct: 127 DRKA-GDRVMVLNRSGMWQEEVTVPSVQTFLIPEAMTFEEAAALLVNYITAYMVLFDFGN 185
Query: 1665 VRPGETLLIHSGSGGVGQAAIAIALSL-GCRVFTTVGSAEKRAYLQARFPQLDSTSFANS 1723
++PG ++L+H +GGVG AA+ + ++ VF T +++ A L +
Sbjct: 186 LQPGHSVLVHMAAGGVGMAAVQLCRTVENVTVFGTASASKHEA--------LKENGVTHP 237
Query: 1724 RDTSFEQHV--LWHTGGKGVDLVLNSLAEEKLQASVRCLATHGRFLEIGKFDLSQNHPLG 1781
D +V + KGVD+V++ L L G+ + G +L
Sbjct: 238 IDYHTTDYVDEIKKISPKGVDIVMDPLGGSDTAKGYNLLKPMGKVVTYGMANLLTGPKRN 297
Query: 1782 MAIFLK------NVT-------------FHGVLLDAFFNESSADWREVWALVQAGIRDGV 1822
+ + +VT FH LD S V A + A G
Sbjct: 298 LMALARTWWNQFSVTALQLLQANRAVCGFHLGYLDGEVELVSG----VVARLLALYNQGH 353
Query: 1823 VRPLKCTVFHGAQVEDAFRYMAQGKHIGKVVV 1854
++P +V+ +V DA + M + K++GKV++
Sbjct: 354 IKPHIDSVWPFEKVADAMKQMQEKKNVGKVLL 385
>gi|194239676 crystallin, zeta isoform b [Homo sapiens]
Length = 295
Score = 58.2 bits (139), Expect = 1e-07
Identities = 29/83 (34%), Positives = 47/83 (56%)
Query: 1621 GLATSVLLSPDFLWDVPSNWTLEEAASVPVVYSTAYYALVVRGRVRPGETLLIHSGSGGV 1680
G A L + ++ +P ++ A++ + Y TAY AL+ V+ GE++L+H SGGV
Sbjct: 102 GYAEYALAADHTVYKLPEKLDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGASGGV 161
Query: 1681 GQAAIAIALSLGCRVFTTVGSAE 1703
G AA IA + G ++ T G+ E
Sbjct: 162 GLAACQIARAYGLKILGTAGTEE 184
>gi|239755236 PREDICTED: similar to Putative uncharacterized protein
C10orf52 [Homo sapiens]
Length = 121
Score = 57.0 bits (136), Expect = 2e-07
Identities = 33/112 (29%), Positives = 56/112 (50%), Gaps = 13/112 (11%)
Query: 13 LPESENLQEFWDNLIGGVDMVTDDDRRWKAGLYGLPRRSGKLKDLSRFDASFFGVHPKQA 72
LPE N++ ++D DD + K+ R+ ++ L+ FD + FG+ +A
Sbjct: 11 LPERLNIEGWYD---------ADDTKPGKSWA----GRAASIERLNEFDNNLFGISDLEA 57
Query: 73 HTMDPQLRLLLEVTYEAIVDGGINPDSLRGTHTGVWVGVSGSETSEALSRDP 124
+DPQ +LLLE TY A+ G+ + G+ TGV++G+ + R P
Sbjct: 58 ECLDPQQKLLLECTYGALESAGVPAKEVAGSRTGVFIGIMNQDYEFMSRRTP 109
>gi|239749764 PREDICTED: hypothetical protein XP_002347152 [Homo
sapiens]
Length = 121
Score = 57.0 bits (136), Expect = 2e-07
Identities = 33/112 (29%), Positives = 56/112 (50%), Gaps = 13/112 (11%)
Query: 13 LPESENLQEFWDNLIGGVDMVTDDDRRWKAGLYGLPRRSGKLKDLSRFDASFFGVHPKQA 72
LPE N++ ++D DD + K+ R+ ++ L+ FD + FG+ +A
Sbjct: 11 LPERLNIEGWYD---------ADDTKPGKSWA----GRAASIERLNEFDNNLFGISDLEA 57
Query: 73 HTMDPQLRLLLEVTYEAIVDGGINPDSLRGTHTGVWVGVSGSETSEALSRDP 124
+DPQ +LLLE TY A+ G+ + G+ TGV++G+ + R P
Sbjct: 58 ECLDPQQKLLLECTYGALESAGVPAKEVAGSRTGVFIGIMNQDYEFMSRRTP 109
>gi|239744023 PREDICTED: hypothetical protein XP_002343020 [Homo
sapiens]
Length = 121
Score = 57.0 bits (136), Expect = 2e-07
Identities = 33/112 (29%), Positives = 56/112 (50%), Gaps = 13/112 (11%)
Query: 13 LPESENLQEFWDNLIGGVDMVTDDDRRWKAGLYGLPRRSGKLKDLSRFDASFFGVHPKQA 72
LPE N++ ++D DD + K+ R+ ++ L+ FD + FG+ +A
Sbjct: 11 LPERLNIEGWYD---------ADDTKPGKSWA----GRAASIERLNEFDNNLFGISDLEA 57
Query: 73 HTMDPQLRLLLEVTYEAIVDGGINPDSLRGTHTGVWVGVSGSETSEALSRDP 124
+DPQ +LLLE TY A+ G+ + G+ TGV++G+ + R P
Sbjct: 58 ECLDPQQKLLLECTYGALESAGVPAKEVAGSRTGVFIGIMNQDYEFMSRRTP 109
>gi|223972627 3-oxoacyl-ACP synthase, mitochondrial isoform 2
precursor [Homo sapiens]
Length = 376
Score = 56.6 bits (135), Expect = 3e-07
Identities = 42/142 (29%), Positives = 61/142 (42%), Gaps = 5/142 (3%)
Query: 264 PSGDIQEQLIRSLYQSAGVAPESFEYIEAHGTGTKVGDPQELNGITRALCATRQEPLLIG 323
P G+ + + + + AGV PE YI AH T T +GD E N + L L +
Sbjct: 236 PEGEGALRCMAAALKDAGVQPEEISYINAHATSTPLGDAAE-NKAIKHLFKDHAYALAVS 294
Query: 324 STKSNMGHPEPASGLAALAKVLLSLEHGLWAPNLHFHSPNPEIPALLDGRLQVVDQPLPV 383
STK GH A+G A L+ + P L+ PE + + Q
Sbjct: 295 STKGATGHLLGAAGAVEAAFTTLACYYQKLPPTLNLDCSEPEFDL---NYVPLKAQEWKT 351
Query: 384 RGGNVGI-NSFGFGGSNVHIIL 404
+G+ NSFGFGG+N + +
Sbjct: 352 EKRFIGLTNSFGFGGTNATLCI 373
Score = 38.1 bits (87), Expect = 0.11
Identities = 48/192 (25%), Positives = 81/192 (42%), Gaps = 26/192 (13%)
Query: 4 VVIAGMSGKLPESENLQEFWDNLIGG----VDMVTDDDRRWKAGLYG-LPRRSGKLKDLS 58
VVI G+ P WD LIGG V +V ++ + + +PR S D
Sbjct: 44 VVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGS----DEG 99
Query: 59 RFDASFFGVHPKQAHTMDPQLRLLLEVTYEAIVDGGINPDSLRG-THTGVWVGVSGSETS 117
+F+ F V +M + + A+ D G +P S TGV +G+ G
Sbjct: 100 QFNEQNF-VSKSDIKSMSSPTIMAIGAAELAMKDSGWHPQSEADQVATGVAIGM-GMIPL 157
Query: 118 EALSRDPETLVGYSMVGCQRA-----------MMANRLSFFFDFRGPSIALDTACSSSLM 166
E +S ET + + G + M A ++S + +GP+ A+ TAC++
Sbjct: 158 EVVS---ETALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAH 214
Query: 167 ALQNAYQAIHSG 178
A+ ++++ I G
Sbjct: 215 AVGDSFRFIAHG 226
>gi|90669511 crystallin, zeta-like 1 [Homo sapiens]
Length = 349
Score = 52.4 bits (124), Expect = 6e-06
Identities = 41/139 (29%), Positives = 63/139 (45%), Gaps = 4/139 (2%)
Query: 1613 VMGLVPAK----GLATSVLLSPDFLWDVPSNWTLEEAASVPVVYSTAYYALVVRGRVRPG 1668
V+G++P GL V + +L P T EAA AY AL + PG
Sbjct: 86 VVGILPLDSEDPGLCEVVRVHEHYLVHKPEKVTWTEAAGSIRDGVRAYTALHYLSHLSPG 145
Query: 1669 ETLLIHSGSGGVGQAAIAIALSLGCRVFTTVGSAEKRAYLQARFPQLDSTSFANSRDTSF 1728
+++LI G+ G AI +A G +V +T S E + L+ P + ++
Sbjct: 146 KSVLIMDGASAFGTIAIQLAHHRGAKVISTACSLEDKQCLERFRPPIARVIDVSNGKVHV 205
Query: 1729 EQHVLWHTGGKGVDLVLNS 1747
+ L TGG GVD+VL++
Sbjct: 206 AESCLEETGGLGVDIVLDA 224
>gi|67078406 trans-2-enoyl-CoA reductase, mitochondrial isoform b
[Homo sapiens]
Length = 297
Score = 51.6 bits (122), Expect = 1e-05
Identities = 36/102 (35%), Positives = 54/102 (52%), Gaps = 10/102 (9%)
Query: 1608 ASGKRVMGLVPAK-------GLAT---SVLLSPDFLWDVPSNWTLEEAASVPVVYSTAYY 1657
A G V GL P GL T + S + L VPS+ L+ AA++ V TAY
Sbjct: 38 AVGSNVTGLKPGDWVIPANAGLGTWRTEAVFSEEALIQVPSDIPLQSAATLGVNPCTAYR 97
Query: 1658 ALVVRGRVRPGETLLIHSGSGGVGQAAIAIALSLGCRVFTTV 1699
L+ +++PG++++ ++ + GVGQA I IA +LG R V
Sbjct: 98 MLMDFEQLQPGDSVIQNASNSGVGQAVIQIAAALGLRTINVV 139
>gi|67078404 trans-2-enoyl-CoA reductase, mitochondrial isoform a
[Homo sapiens]
Length = 373
Score = 51.6 bits (122), Expect = 1e-05
Identities = 36/102 (35%), Positives = 54/102 (52%), Gaps = 10/102 (9%)
Query: 1608 ASGKRVMGLVPAK-------GLAT---SVLLSPDFLWDVPSNWTLEEAASVPVVYSTAYY 1657
A G V GL P GL T + S + L VPS+ L+ AA++ V TAY
Sbjct: 114 AVGSNVTGLKPGDWVIPANAGLGTWRTEAVFSEEALIQVPSDIPLQSAATLGVNPCTAYR 173
Query: 1658 ALVVRGRVRPGETLLIHSGSGGVGQAAIAIALSLGCRVFTTV 1699
L+ +++PG++++ ++ + GVGQA I IA +LG R V
Sbjct: 174 MLMDFEQLQPGDSVIQNASNSGVGQAVIQIAAALGLRTINVV 215
>gi|226059159 prostaglandin reductase 1 isoform 1 [Homo sapiens]
Length = 329
Score = 48.9 bits (115), Expect = 6e-05
Identities = 49/206 (23%), Positives = 91/206 (44%), Gaps = 9/206 (4%)
Query: 1654 TAYYALVVRGRVRPGETLLIHSGSGGVGQAAIAIALSLGCRVFTTVGSAEKRAYLQARFP 1713
TAY+ L+ V+ GET+++++ +G VG IA GC+V VGS EK AYLQ
Sbjct: 128 TAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVAYLQ---- 183
Query: 1714 QLDSTSFANSRDTSFEQHVLWHTGGKGVDLVLNSLAEEKLQASVRCLATHGRFLEIGKFD 1773
+L N + + L G D +++ E + + GR G
Sbjct: 184 KLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQMKKFGRIAICGAIS 243
Query: 1774 -LSQNHPLGMAIFLKNVTFHGVLLDAFFN---ESSADWREVWALVQAGIRDGVVRPLKCT 1829
++ PL + V + + ++AF + A + + L++ + +G ++ +
Sbjct: 244 TYNRTGPLPPGPPPEIVIYQELRMEAFVVYRWQGDARQKALKDLLK-WVLEGKIQYKEYI 302
Query: 1830 VFHGAQVEDAFRYMAQGKHIGKVVVQ 1855
+ + AF M +G ++GK +V+
Sbjct: 303 IEGFENMPAAFMGMLKGDNLGKTIVK 328
>gi|226059133 prostaglandin reductase 1 isoform 1 [Homo sapiens]
Length = 329
Score = 48.9 bits (115), Expect = 6e-05
Identities = 49/206 (23%), Positives = 91/206 (44%), Gaps = 9/206 (4%)
Query: 1654 TAYYALVVRGRVRPGETLLIHSGSGGVGQAAIAIALSLGCRVFTTVGSAEKRAYLQARFP 1713
TAY+ L+ V+ GET+++++ +G VG IA GC+V VGS EK AYLQ
Sbjct: 128 TAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVAYLQ---- 183
Query: 1714 QLDSTSFANSRDTSFEQHVLWHTGGKGVDLVLNSLAEEKLQASVRCLATHGRFLEIGKFD 1773
+L N + + L G D +++ E + + GR G
Sbjct: 184 KLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQMKKFGRIAICGAIS 243
Query: 1774 -LSQNHPLGMAIFLKNVTFHGVLLDAFFN---ESSADWREVWALVQAGIRDGVVRPLKCT 1829
++ PL + V + + ++AF + A + + L++ + +G ++ +
Sbjct: 244 TYNRTGPLPPGPPPEIVIYQELRMEAFVVYRWQGDARQKALKDLLK-WVLEGKIQYKEYI 302
Query: 1830 VFHGAQVEDAFRYMAQGKHIGKVVVQ 1855
+ + AF M +G ++GK +V+
Sbjct: 303 IEGFENMPAAFMGMLKGDNLGKTIVK 328
>gi|51243059 mitochondrial malonyltransferase isoform a precursor
[Homo sapiens]
Length = 390
Score = 48.5 bits (114), Expect = 8e-05
Identities = 80/328 (24%), Positives = 123/328 (37%), Gaps = 45/328 (13%)
Query: 478 GGPEVQQVPAGERPLWFICS-----GMGTQWRGMGLSLMRLDRFRDSILRSDEAVKPFGL 532
G E A ER + CS G G+Q GMG L+ R R+ A + G
Sbjct: 44 GAEEEAPWAATERRMPGQCSVLLFPGQGSQVVGMGRGLLNYPRVRELYA---AARRVLGY 100
Query: 533 KVSQLLLSTDESTFDDIVHSFVSLTAIQIGLIDLLSCMGLRPDGI------VGHSLGEVA 586
+ +L L + T D VH ++ + ++ L L+P I G S+GE A
Sbjct: 101 DLLELSLHGPQETLDRTVHCQPAIFVASLAAVEKLH--HLQPSVIENCVAAAGFSVGEFA 158
Query: 587 CGYADGCLSQEEAVLAAYWRGQCIKEAH--LPPGAMAAVG-------LSWEECKQRCPPG 637
G + E + A R + ++EA +P G ++ +G + E ++ C
Sbjct: 159 ALVFAGAMEFAEGLYAVKIRAEAMQEASEAVPSGMLSVLGQPQSKFNFACLEAREHCKSL 218
Query: 638 VV--PACHNSK----DTVTISGPQAPVFEFVEQLRKEGVFAKEVRTGGMAFHSYFMEAIA 691
+ P C S D ISG Q + + K + AFH+ ME
Sbjct: 219 GIENPVCEVSNYLFPDCRVISGHQEALRFLQKNSSKFHFRRTRMLPVSGAFHTRLMEPAV 278
Query: 692 PPLLQELKKV-IREPKPRSARWLSTSIPEAQWHSSLARTSSAEYNVNNLVSPVLFQEALW 750
PL Q LK V I++P L + H + LVSPV +++ +
Sbjct: 279 EPLTQALKAVDIKKP-------LVSVYSNVHAHRYRHPGHIHKLLAQQLVSPVKWEQTMH 331
Query: 751 HVPEH------AVVLEIAPHALLQAVLK 772
+ E E+ P L A+LK
Sbjct: 332 AIYERKKGRGFPQTFEVGPGRQLGAILK 359
>gi|226056130 prostaglandin reductase 1 isoform 2 [Homo sapiens]
Length = 301
Score = 48.1 bits (113), Expect = 1e-04
Identities = 25/56 (44%), Positives = 35/56 (62%)
Query: 1654 TAYYALVVRGRVRPGETLLIHSGSGGVGQAAIAIALSLGCRVFTTVGSAEKRAYLQ 1709
TAY+ L+ V+ GET+++++ +G VG IA GC+V VGS EK AYLQ
Sbjct: 128 TAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVAYLQ 183
>gi|4501929 class I alcohol dehydrogenase, alpha subunit [Homo
sapiens]
Length = 375
Score = 38.9 bits (89), Expect = 0.064
Identities = 44/161 (27%), Positives = 68/161 (42%), Gaps = 7/161 (4%)
Query: 1642 LEEAASVPVVYSTAYYALVVRGRVRPGETLLIHSGSGGVGQAAIAIALSLGCRVFTTVGS 1701
LE+ + +ST Y + V +V PG T + G GGVG +AI + G V
Sbjct: 167 LEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVF-GLGGVGLSAIMGCKAAGAARIIAV-D 224
Query: 1702 AEKRAYLQARFPQLDSTSFANSRDTSFE-QHVLWHTGGKGVDLVLNSLAE-EKLQASVRC 1759
K + +A+ +L +T N +D Q VL GVD + + + AS+ C
Sbjct: 225 INKDKFAKAK--ELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLC 282
Query: 1760 L-ATHGRFLEIGKFDLSQNHPLGMAIFLKNVTFHGVLLDAF 1799
G + +G SQN + + L T+ G +L F
Sbjct: 283 CHEACGTSVIVGVPPDSQNLSMNPMLLLTGRTWKGAILGGF 323
>gi|4501933 class I alcohol dehydrogenase, gamma subunit [Homo
sapiens]
Length = 375
Score = 38.5 bits (88), Expect = 0.084
Identities = 46/199 (23%), Positives = 81/199 (40%), Gaps = 7/199 (3%)
Query: 1609 SGKRVMGLVPAKGLATSVLLSPDFLWDVPSNWTLEEAASVPVVYSTAYYALVVRGRVRPG 1668
SGK + V + ++ + + + + LE+ + +ST Y + V +V PG
Sbjct: 134 SGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPG 193
Query: 1669 ETLLIHSGSGGVGQAAIAIALSLGCRVFTTVGSAEKRAYLQARFPQLDSTSFANSRDTSF 1728
T + G GGVG + + + G V K + +A+ +L +T N +D
Sbjct: 194 STCAVF-GLGGVGLSVVMGCKAAGAARIIAV-DINKDKFAKAK--ELGATECINPQDYKK 249
Query: 1729 E-QHVLWHTGGKGVDLVLNSLAE-EKLQASVRCL-ATHGRFLEIGKFDLSQNHPLGMAIF 1785
Q VL GVD + + + AS+ C G + +G SQN + +
Sbjct: 250 PIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPMLL 309
Query: 1786 LKNVTFHGVLLDAFFNESS 1804
L T+ G + F ++ S
Sbjct: 310 LTGRTWKGAIFGGFKSKES 328
>gi|71565152 class II alcohol dehydrogenase, pi subunit [Homo sapiens]
Length = 380
Score = 38.1 bits (87), Expect = 0.11
Identities = 69/283 (24%), Positives = 117/283 (41%), Gaps = 26/283 (9%)
Query: 1581 GKLSPDAIPGKWTSQDSLLGMEFSGRDASGKRVMGLVPAKGLATSVLLSPDFLWDVPSNW 1640
GK+S P S L+ + S GK V + ++S L + +
Sbjct: 114 GKISNLKSPA---SDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDA 170
Query: 1641 TLEEAASVPVVYSTAYYALVVRGRVRPGETLLIHSGSGGVGQAAIAIALSLGC-RVFTTV 1699
LE + +ST Y A + +V PG T + G GGVG +A+ + G R+
Sbjct: 171 NLERVCLLGCGFSTGYGAAINNAKVTPGSTCAVF-GLGGVGLSAVMGCKAAGASRIIGID 229
Query: 1700 GSAEKRAYLQARFPQLDSTSFANSRDTSFE-QHVLWHTGGKGVDLVLNSL-AEEKLQASV 1757
++EK +++A+ L +T N RD Q V+ GVD L+ E ++A++
Sbjct: 230 INSEK--FVKAK--ALGATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAAL 285
Query: 1758 RC-LATHGRFLEIGKFDLSQNHPLGMAIFLKNVTFHGVLLDAFFNESSADWREVWALVQA 1816
C A G IG S+ G+ IF + + + FF W+ V ++ +
Sbjct: 286 DCTTAGWGSCTFIGVAAGSK----GLTIFPEELIIGRTINGTFF----GGWKSVDSIPKL 337
Query: 1817 GIRDGVVRP--LKCTVFHGA---QVEDAFRYMAQGKHIGKVVV 1854
+ D + L V H ++ +AF M QGK + +++
Sbjct: 338 -VTDYKNKKFNLDALVTHTLPFDKISEAFDLMNQGKSVRTILI 379
>gi|34577061 class I alcohol dehydrogenase, beta subunit [Homo
sapiens]
Length = 375
Score = 37.4 bits (85), Expect = 0.19
Identities = 42/161 (26%), Positives = 67/161 (41%), Gaps = 7/161 (4%)
Query: 1642 LEEAASVPVVYSTAYYALVVRGRVRPGETLLIHSGSGGVGQAAIAIALSLGCRVFTTVGS 1701
LE+ + +ST Y + V +V PG T + G GGVG +A+ + G V
Sbjct: 167 LEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVF-GLGGVGLSAVMGCKAAGAARIIAV-D 224
Query: 1702 AEKRAYLQARFPQLDSTSFANSRDTSFE-QHVLWHTGGKGVDLVLNSLAE-EKLQASVRC 1759
K + +A+ +L +T N +D Q VL GVD + + + AS+ C
Sbjct: 225 INKDKFAKAK--ELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLC 282
Query: 1760 L-ATHGRFLEIGKFDLSQNHPLGMAIFLKNVTFHGVLLDAF 1799
G + +G SQN + + L T+ G + F
Sbjct: 283 CHEACGTSVIVGVPPASQNLSINPMLLLTGRTWKGAVYGGF 323
>gi|4504505 hydroxysteroid (17-beta) dehydrogenase 4 [Homo sapiens]
Length = 736
Score = 35.0 bits (79), Expect = 0.93
Identities = 43/173 (24%), Positives = 69/173 (39%), Gaps = 11/173 (6%)
Query: 1888 IIAGGLGGFGLELAQWLIQRGVQKLVLT---SRSGIRTGYQA--KQVRRWRRQGVQVQVS 1942
++ G G G A +RG +V G+ G A K V RR+G + +
Sbjct: 13 LVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEIRRRGGK---A 69
Query: 1943 TSNISSLEGARGLIAEAAQ-LGPVGGVFNLAVVLRDGLLENQTPEFFQDVCKPKYSGTLN 2001
+N S+E ++ A G + V N A +LRD + E + + + G+
Sbjct: 70 VANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRVHLRGSFQ 129
Query: 2002 LDRVTREACPELDY--FVVFSSVSCGRGNAGQSNYGFANSAMERICEKRRHEG 2052
+ R E + Y ++ SS S GN GQ+NY A + + EG
Sbjct: 130 VTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEG 182
>gi|194097330 hexokinase 3 [Homo sapiens]
Length = 923
Score = 34.3 bits (77), Expect = 1.6
Identities = 56/236 (23%), Positives = 90/236 (38%), Gaps = 35/236 (14%)
Query: 1964 PVGGVFNLA---VVLRDGLLENQTPEFFQDVCKPKYSGTLNLDRVTREACPELDYFVVFS 2020
P+G F+ + L G+L N T F C+ + +L + +TR EL+ + +
Sbjct: 603 PLGFTFSFPCRQLGLDQGILLNWTKGFKASDCEGQDVVSLLREAITRRQAVELNVVAIVN 662
Query: 2021 S-----VSCGRGNAGQSNYGFANSAMERIC---EKRRHEGLPG------LAVQWGAIGDV 2066
+SCG + + G C E R G+PG + ++WGA GD
Sbjct: 663 DTVGTMMSCGYEDP-RCEIGLIVGTGTNACYMEELRNVAGVPGDSGRMCINMEWGAFGDD 721
Query: 2067 GILVETMSTNDTIVSGTL----PQRMASCLEVLDLFLNQPHMVLSSFVLAEKAAAYRDRD 2122
G L + D V QR + + L H++L L +R +
Sbjct: 722 GSLAMLSTRFDASVDQASINPGKQRFEKMISGMYLGEIVRHILLH---LTSLGVLFRGQQ 778
Query: 2123 SQR----------DLVEAVAHILGIRDLAAVNLDSSLADLGLDSLMSVEVRQTLER 2168
QR L E + L +R + A+ D L D+LM +EV Q + +
Sbjct: 779 IQRLQTRDIFKTKFLSEIESDSLALRQVRAILEDLGLPLTSDDALMVLEVCQAVSQ 834
>gi|156523966 class V alcohol dehydrogenase isoform 1 [Homo sapiens]
Length = 375
Score = 33.5 bits (75), Expect = 2.7
Identities = 34/155 (21%), Positives = 63/155 (40%), Gaps = 7/155 (4%)
Query: 1642 LEEAASVPVVYSTAYYALVVRGRVRPGETLLIHSGSGGVGQAAIAIALSLGCRVFTTVGS 1701
LE+ + +ST + A + +V PG T + G GGVG + + + G V
Sbjct: 167 LEKVCLISCGFSTGFGAAINTAKVTPGSTCAVF-GLGGVGLSVVMGCKAAGAARIIGV-D 224
Query: 1702 AEKRAYLQARFPQLDSTSFANSRDTSFE-QHVLWHTGGKGVDLVLNSLAEEKLQAS--VR 1758
K + +A+ +L +T N +D Q VL+ G+D ++ + A+
Sbjct: 225 VNKEKFKKAQ--ELGATECLNPQDLKKPIQEVLFDMTDAGIDFCFEAIGNLDVLAAALAS 282
Query: 1759 CLATHGRFLEIGKFDLSQNHPLGMAIFLKNVTFHG 1793
C ++G + +G S + +F + G
Sbjct: 283 CNESYGVCVVVGVLPASVQLKISGQLFFSGRSLKG 317
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.405
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 99,425,844
Number of Sequences: 37866
Number of extensions: 4785575
Number of successful extensions: 12544
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 12478
Number of HSP's gapped (non-prelim): 71
length of query: 2511
length of database: 18,247,518
effective HSP length: 119
effective length of query: 2392
effective length of database: 13,741,464
effective search space: 32869581888
effective search space used: 32869581888
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 71 (32.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.