Guide to the Human Genome
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Name: HSD17B4 Sequence: fasta or formatted (736aa) NCBI GI: 4504505
Description:

hydroxysteroid (17-beta) dehydrogenase 4

Referenced in:

Alcohol and Aldehyde Dehydrogenases
Cholesterol Biosynthesis
Peroxisomes
Steroid Hormones

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             9.4         69           2
 C cysteine            1.1          8           1
 D aspartate           5.0         37           1
 E glutamate           5.6         41           2
 F phenylalanine       4.3         32           2
 G glycine            10.6         78           3
 H histidine           1.8         13           1
 I isoleucine          6.2         46           2
 K lysine              7.5         55           2
 L leucine             8.4         62           2
 M methionine          1.9         14           2
 N asparagine          3.7         27           2
 P proline             3.8         28           2
 Q glutamine           3.1         23           2
 R arginine            4.6         34           3
 S serine              7.1         52           2
 T threonine           4.5         33           2
 V valine              7.5         55           3
 W tryptophan          1.4         10           1
 Y tyrosine            2.6         19           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   hydroxysteroid (17-beta) dehydrogenase 4 
C20orf79              0.069   hypothetical protein LOC140856 
HSD17B8               0.053   estradiol 17 beta-dehydrogenase 8 
SCP2                  0.044   sterol carrier protein 2 isoform 1 proprotein 
SCP2                  0.044   sterol carrier protein 2 isoform 2 precursor 
SCP2                  0.044   sterol carrier protein 2 isoform 1 precursor 
BDH2                  0.043   3-hydroxybutyrate dehydrogenase, type 2 
RDH10                 0.041   retinol dehydrogenase 10 
KDSR                  0.040   3-ketodihydrosphingosine reductase precursor 
DHRS4                 0.039   peroxisomal short-chain alcohol dehydrogenase 
CBR4                  0.038   carbonic reductase 4 
SDR16C6               0.037   short chain dehydrogenase/reductase family 16C, mem...
SDR16C5               0.037   epidermal retinal dehydrogenase 2 
PECR                  0.033   peroxisomal trans-2-enoyl-CoA reductase 
HSDL2                 0.033   hydroxysteroid dehydrogenase like 2 
HSD17B10              0.031   hydroxysteroid (17-beta) dehydrogenase 10 isoform 1 [...
DHRS4L2               0.031   dehydrogenase/reductase (SDR family) member 4 like ...
HPGD                  0.030   hydroxyprostaglandin dehydrogenase 15-(NAD) isoform ...
HSD17B13              0.029   hydroxysteroid (17-beta) dehydrogenase 13 isoform A...
DHRS3                 0.028   dehydrogenase/reductase (SDR family) member 3 
HSD17B14              0.028   dehydrogenase/reductase (SDR family) member 10 [Homo...
HPGD                  0.027   hydroxyprostaglandin dehydrogenase 15-(NAD) isoform...
HSD17B10              0.026   hydroxysteroid (17-beta) dehydrogenase 10 isoform 2 ...
DHRS2                 0.025   dehydrogenase/reductase member 2 isoform 2 
DHRS2                 0.025   dehydrogenase/reductase member 2 isoform 1 
HSD17B11              0.024   estradiol 17-beta-dehydrogenase 11 
HSD17B3               0.024   estradiol 17 beta-dehydrogenase 3 
DHRS1                 0.024   dehydrogenase/reductase (SDR family) member 1 [Homo...
DHRS1                 0.024   dehydrogenase/reductase (SDR family) member 1 
DHRS7B                0.022   dehydrogenase/reductase (SDR family) member 7B [Homo...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
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