Guide to the Human Genome
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Search of human proteins with 41393579

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|41393579 PDZ domain protein GIPC2 [Homo sapiens]
         (315 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|41393579 PDZ domain protein GIPC2 [Homo sapiens]                   622   e-178
gi|42544140 regulator of G-protein signalling 19 interacting pro...   385   e-107
gi|42544144 regulator of G-protein signalling 19 interacting pro...   385   e-107
gi|5031715 regulator of G-protein signalling 19 interacting prot...   385   e-107
gi|18959204 GIPC PDZ domain containing family, member 3 [Homo sa...   337   1e-92
gi|42544142 regulator of G-protein signalling 19 interacting pro...   322   2e-88
gi|42544146 regulator of G-protein signalling 19 interacting pro...   322   2e-88
gi|42544149 regulator of G-protein signalling 19 interacting pro...   322   2e-88
gi|186972120 calcium/calmodulin-dependent serine protein kinase ...    44   2e-04
gi|186700629 calcium/calmodulin-dependent serine protein kinase ...    42   0.001
gi|186700627 calcium/calmodulin-dependent serine protein kinase ...    42   0.001
gi|148746189 multiple PDZ domain protein [Homo sapiens]                42   0.001
gi|87196343 PDZ domain containing 2 [Homo sapiens]                     41   0.001
gi|4507137 acidic alpha 1 syntrophin [Homo sapiens]                    39   0.005
gi|93204861 protein phosphatase 1, regulatory (inhibitor) subuni...    39   0.006
gi|4505237 palmitoylated membrane protein 1 [Homo sapiens]             39   0.008
gi|27436957 membrane associated guanylate kinase, WW and PDZ dom...    39   0.008
gi|223890252 glutamate receptor interacting protein 1 [Homo sapi...    38   0.010
gi|111154074 palmitoylated membrane protein 7 [Homo sapiens]           38   0.010
gi|88758603 protein interacting with C kinase 1 [Homo sapiens]         38   0.013
gi|88758600 protein interacting with C kinase 1 [Homo sapiens]         38   0.013
gi|7110697 protein interacting with C kinase 1 [Homo sapiens]          38   0.013
gi|218156340 chapsyn-110 isoform 3 [Homo sapiens]                      37   0.030
gi|218156338 chapsyn-110 isoform 1 [Homo sapiens]                      37   0.030
gi|91199538 chapsyn-110 isoform 2 [Homo sapiens]                       37   0.030
gi|122937249 glutamate receptor interacting protein 2 [Homo sapi...    37   0.030
gi|112382257 InaD-like [Homo sapiens]                                  36   0.039
gi|21536464 palmitoylated membrane protein 3 [Homo sapiens]            36   0.039
gi|148833504 interleukin 16 isoform 2 [Homo sapiens]                   36   0.051
gi|218505835 membrane-associated guanylate kinase-related  3 iso...    36   0.051

>gi|41393579 PDZ domain protein GIPC2 [Homo sapiens]
          Length = 315

 Score =  622 bits (1604), Expect = e-178
 Identities = 315/315 (100%), Positives = 315/315 (100%)

Query: 1   MPLKLRGKKKAKSKETAGLVEGEPTGAGGGSLSASRAPARRLVFHAQLAHGSATGRVEGF 60
           MPLKLRGKKKAKSKETAGLVEGEPTGAGGGSLSASRAPARRLVFHAQLAHGSATGRVEGF
Sbjct: 1   MPLKLRGKKKAKSKETAGLVEGEPTGAGGGSLSASRAPARRLVFHAQLAHGSATGRVEGF 60

Query: 61  SSIQELYAQIAGAFEISPSEILYCTLNTPKIDMERLLGGQLGLEDFIFAHVKGIEKEVNV 120
           SSIQELYAQIAGAFEISPSEILYCTLNTPKIDMERLLGGQLGLEDFIFAHVKGIEKEVNV
Sbjct: 61  SSIQELYAQIAGAFEISPSEILYCTLNTPKIDMERLLGGQLGLEDFIFAHVKGIEKEVNV 120

Query: 121 YKSEDSLGLTITDNGVGYAFIKRIKDGGVIDSVKTICVGDHIESINGENIVGWRHYDVAK 180
           YKSEDSLGLTITDNGVGYAFIKRIKDGGVIDSVKTICVGDHIESINGENIVGWRHYDVAK
Sbjct: 121 YKSEDSLGLTITDNGVGYAFIKRIKDGGVIDSVKTICVGDHIESINGENIVGWRHYDVAK 180

Query: 181 KLKELKKEELFTMKLIEPKKAFEIELRSKAGKSSGEKIGCGRATLRLRSKGPATVEEMPS 240
           KLKELKKEELFTMKLIEPKKAFEIELRSKAGKSSGEKIGCGRATLRLRSKGPATVEEMPS
Sbjct: 181 KLKELKKEELFTMKLIEPKKAFEIELRSKAGKSSGEKIGCGRATLRLRSKGPATVEEMPS 240

Query: 241 ETKAKAIEKIDDVLELYMGIRDIDLATTMFEAGKDKVNPDEFAVALDETLGDFAFPDEFV 300
           ETKAKAIEKIDDVLELYMGIRDIDLATTMFEAGKDKVNPDEFAVALDETLGDFAFPDEFV
Sbjct: 241 ETKAKAIEKIDDVLELYMGIRDIDLATTMFEAGKDKVNPDEFAVALDETLGDFAFPDEFV 300

Query: 301 FDVWGVIGDAKRRGL 315
           FDVWGVIGDAKRRGL
Sbjct: 301 FDVWGVIGDAKRRGL 315


>gi|42544140 regulator of G-protein signalling 19 interacting
           protein 1 isoform 1 [Homo sapiens]
          Length = 333

 Score =  385 bits (988), Expect = e-107
 Identities = 202/329 (61%), Positives = 247/329 (75%), Gaps = 18/329 (5%)

Query: 1   MPLKLRGKKKA----KSKET----AGLVEGEPTGAGGGSLSASR--------APARRLVF 44
           MPL L  +KKA    +++E      GL  GEP   GGG     +        A   RLVF
Sbjct: 1   MPLGLGRRKKAPPLVENEEAEPGRGGLGVGEPGPLGGGGSGGPQMGLPPPPPALRPRLVF 60

Query: 45  HAQLAHGSATGRVEGFSSIQELYAQIAGAFEISPSEILYCTLNTPKIDMERLLGGQLGLE 104
           H QLAHGS TGR+EGF++++ELY +IA AF +  +E+++CTLNT K+DM++LLGGQ+GLE
Sbjct: 61  HTQLAHGSPTGRIEGFTNVKELYGKIAEAFRLPTAEVMFCTLNTHKVDMDKLLGGQIGLE 120

Query: 105 DFIFAHVKGIEKEVNVYKSEDSLGLTITDNGVGYAFIKRIKDGGVIDSVKTICVGDHIES 164
           DFIFAHVKG  KEV V+KSED+LGLTITDNG GYAFIKRIK+G VID +  I VGD IE+
Sbjct: 121 DFIFAHVKGQRKEVEVFKSEDALGLTITDNGAGYAFIKRIKEGSVIDHIHLISVGDMIEA 180

Query: 165 INGENIVGWRHYDVAKKLKELKKEELFTMKLIEPKKAFE-IELRSKAGK-SSGEKIGCGR 222
           ING++++G RHY+VA+ LKEL +   FT+KL EP+KAF+ I  RS  G+  SG ++G GR
Sbjct: 181 INGQSLLGCRHYEVARLLKELPRGRTFTLKLTEPRKAFDMISQRSAGGRPGSGPQLGTGR 240

Query: 223 ATLRLRSKGPATVEEMPSETKAKAIEKIDDVLELYMGIRDIDLATTMFEAGKDKVNPDEF 282
            TLRLRS+GPATVE++PS  + KAIEK+DD+LE YMGIRD +LA TM E GKDK NPDE 
Sbjct: 241 GTLRLRSRGPATVEDLPSAFEEKAIEKVDDLLESYMGIRDTELAATMVELGKDKRNPDEL 300

Query: 283 AVALDETLGDFAFPDEFVFDVWGVIGDAK 311
           A ALDE LGDFAFPDEFVFDVWG IGDAK
Sbjct: 301 AEALDERLGDFAFPDEFVFDVWGAIGDAK 329


>gi|42544144 regulator of G-protein signalling 19 interacting
           protein 1 isoform 1 [Homo sapiens]
          Length = 333

 Score =  385 bits (988), Expect = e-107
 Identities = 202/329 (61%), Positives = 247/329 (75%), Gaps = 18/329 (5%)

Query: 1   MPLKLRGKKKA----KSKET----AGLVEGEPTGAGGGSLSASR--------APARRLVF 44
           MPL L  +KKA    +++E      GL  GEP   GGG     +        A   RLVF
Sbjct: 1   MPLGLGRRKKAPPLVENEEAEPGRGGLGVGEPGPLGGGGSGGPQMGLPPPPPALRPRLVF 60

Query: 45  HAQLAHGSATGRVEGFSSIQELYAQIAGAFEISPSEILYCTLNTPKIDMERLLGGQLGLE 104
           H QLAHGS TGR+EGF++++ELY +IA AF +  +E+++CTLNT K+DM++LLGGQ+GLE
Sbjct: 61  HTQLAHGSPTGRIEGFTNVKELYGKIAEAFRLPTAEVMFCTLNTHKVDMDKLLGGQIGLE 120

Query: 105 DFIFAHVKGIEKEVNVYKSEDSLGLTITDNGVGYAFIKRIKDGGVIDSVKTICVGDHIES 164
           DFIFAHVKG  KEV V+KSED+LGLTITDNG GYAFIKRIK+G VID +  I VGD IE+
Sbjct: 121 DFIFAHVKGQRKEVEVFKSEDALGLTITDNGAGYAFIKRIKEGSVIDHIHLISVGDMIEA 180

Query: 165 INGENIVGWRHYDVAKKLKELKKEELFTMKLIEPKKAFE-IELRSKAGK-SSGEKIGCGR 222
           ING++++G RHY+VA+ LKEL +   FT+KL EP+KAF+ I  RS  G+  SG ++G GR
Sbjct: 181 INGQSLLGCRHYEVARLLKELPRGRTFTLKLTEPRKAFDMISQRSAGGRPGSGPQLGTGR 240

Query: 223 ATLRLRSKGPATVEEMPSETKAKAIEKIDDVLELYMGIRDIDLATTMFEAGKDKVNPDEF 282
            TLRLRS+GPATVE++PS  + KAIEK+DD+LE YMGIRD +LA TM E GKDK NPDE 
Sbjct: 241 GTLRLRSRGPATVEDLPSAFEEKAIEKVDDLLESYMGIRDTELAATMVELGKDKRNPDEL 300

Query: 283 AVALDETLGDFAFPDEFVFDVWGVIGDAK 311
           A ALDE LGDFAFPDEFVFDVWG IGDAK
Sbjct: 301 AEALDERLGDFAFPDEFVFDVWGAIGDAK 329


>gi|5031715 regulator of G-protein signalling 19 interacting protein
           1 isoform 1 [Homo sapiens]
          Length = 333

 Score =  385 bits (988), Expect = e-107
 Identities = 202/329 (61%), Positives = 247/329 (75%), Gaps = 18/329 (5%)

Query: 1   MPLKLRGKKKA----KSKET----AGLVEGEPTGAGGGSLSASR--------APARRLVF 44
           MPL L  +KKA    +++E      GL  GEP   GGG     +        A   RLVF
Sbjct: 1   MPLGLGRRKKAPPLVENEEAEPGRGGLGVGEPGPLGGGGSGGPQMGLPPPPPALRPRLVF 60

Query: 45  HAQLAHGSATGRVEGFSSIQELYAQIAGAFEISPSEILYCTLNTPKIDMERLLGGQLGLE 104
           H QLAHGS TGR+EGF++++ELY +IA AF +  +E+++CTLNT K+DM++LLGGQ+GLE
Sbjct: 61  HTQLAHGSPTGRIEGFTNVKELYGKIAEAFRLPTAEVMFCTLNTHKVDMDKLLGGQIGLE 120

Query: 105 DFIFAHVKGIEKEVNVYKSEDSLGLTITDNGVGYAFIKRIKDGGVIDSVKTICVGDHIES 164
           DFIFAHVKG  KEV V+KSED+LGLTITDNG GYAFIKRIK+G VID +  I VGD IE+
Sbjct: 121 DFIFAHVKGQRKEVEVFKSEDALGLTITDNGAGYAFIKRIKEGSVIDHIHLISVGDMIEA 180

Query: 165 INGENIVGWRHYDVAKKLKELKKEELFTMKLIEPKKAFE-IELRSKAGK-SSGEKIGCGR 222
           ING++++G RHY+VA+ LKEL +   FT+KL EP+KAF+ I  RS  G+  SG ++G GR
Sbjct: 181 INGQSLLGCRHYEVARLLKELPRGRTFTLKLTEPRKAFDMISQRSAGGRPGSGPQLGTGR 240

Query: 223 ATLRLRSKGPATVEEMPSETKAKAIEKIDDVLELYMGIRDIDLATTMFEAGKDKVNPDEF 282
            TLRLRS+GPATVE++PS  + KAIEK+DD+LE YMGIRD +LA TM E GKDK NPDE 
Sbjct: 241 GTLRLRSRGPATVEDLPSAFEEKAIEKVDDLLESYMGIRDTELAATMVELGKDKRNPDEL 300

Query: 283 AVALDETLGDFAFPDEFVFDVWGVIGDAK 311
           A ALDE LGDFAFPDEFVFDVWG IGDAK
Sbjct: 301 AEALDERLGDFAFPDEFVFDVWGAIGDAK 329


>gi|18959204 GIPC PDZ domain containing family, member 3 [Homo
           sapiens]
          Length = 312

 Score =  337 bits (863), Expect = 1e-92
 Identities = 167/273 (61%), Positives = 216/273 (79%), Gaps = 2/273 (0%)

Query: 41  RLVFHAQLAHGSATGRVEGFSSIQELYAQIAGAFEISPSEILYCTLNTPKIDMERLLGGQ 100
           RLVF  QLAHGS TG++EGF++++ELYA+IA AF I+P+EIL+CTLN+ K+DM++LLGGQ
Sbjct: 36  RLVFRTQLAHGSPTGKIEGFTNVRELYAKIAEAFGIAPTEILFCTLNSHKVDMQKLLGGQ 95

Query: 101 LGLEDFIFAHVKGIEKEVNVYKSEDSLGLTITDNGVGYAFIKRIKDGGVIDSVKTICVGD 160
           +GLEDFIFAHV+G  KEV V K+ED+LGLTITDNG GYAFIKRIK+G +I+ ++ +CVGD
Sbjct: 96  IGLEDFIFAHVRGETKEVEVTKTEDALGLTITDNGAGYAFIKRIKEGSIINRIEAVCVGD 155

Query: 161 HIESINGENIVGWRHYDVAKKLKELKKEELFTMKLIEPKKAFE-IELRSKAGKSSGE-KI 218
            IE+IN  +IVG RHY+VAK L+EL K + FT++L++PK+AF+ I  RS++ K   E K+
Sbjct: 156 SIEAINDHSIVGCRHYEVAKMLRELPKSQPFTLRLVQPKRAFDMIGQRSRSSKCPVEAKV 215

Query: 219 GCGRATLRLRSKGPATVEEMPSETKAKAIEKIDDVLELYMGIRDIDLATTMFEAGKDKVN 278
             GR TLRLRS G ATVEE PSE + +A  K+DD+LE YMGIRD +LA+TM E  K   +
Sbjct: 216 TSGRETLRLRSGGAATVEEAPSEFEEEASRKVDDLLESYMGIRDPELASTMVETSKKTAS 275

Query: 279 PDEFAVALDETLGDFAFPDEFVFDVWGVIGDAK 311
             EFA  LD  LG+FAFPDEFV +VW  IG+A+
Sbjct: 276 AQEFARCLDSVLGEFAFPDEFVVEVWAAIGEAR 308


>gi|42544142 regulator of G-protein signalling 19 interacting
           protein 1 isoform 2 [Homo sapiens]
          Length = 236

 Score =  322 bits (826), Expect = 2e-88
 Identities = 160/232 (68%), Positives = 191/232 (82%), Gaps = 2/232 (0%)

Query: 82  LYCTLNTPKIDMERLLGGQLGLEDFIFAHVKGIEKEVNVYKSEDSLGLTITDNGVGYAFI 141
           ++CTLNT K+DM++LLGGQ+GLEDFIFAHVKG  KEV V+KSED+LGLTITDNG GYAFI
Sbjct: 1   MFCTLNTHKVDMDKLLGGQIGLEDFIFAHVKGQRKEVEVFKSEDALGLTITDNGAGYAFI 60

Query: 142 KRIKDGGVIDSVKTICVGDHIESINGENIVGWRHYDVAKKLKELKKEELFTMKLIEPKKA 201
           KRIK+G VID +  I VGD IE+ING++++G RHY+VA+ LKEL +   FT+KL EP+KA
Sbjct: 61  KRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTLKLTEPRKA 120

Query: 202 FE-IELRSKAGK-SSGEKIGCGRATLRLRSKGPATVEEMPSETKAKAIEKIDDVLELYMG 259
           F+ I  RS  G+  SG ++G GR TLRLRS+GPATVE++PS  + KAIEK+DD+LE YMG
Sbjct: 121 FDMISQRSAGGRPGSGPQLGTGRGTLRLRSRGPATVEDLPSAFEEKAIEKVDDLLESYMG 180

Query: 260 IRDIDLATTMFEAGKDKVNPDEFAVALDETLGDFAFPDEFVFDVWGVIGDAK 311
           IRD +LA TM E GKDK NPDE A ALDE LGDFAFPDEFVFDVWG IGDAK
Sbjct: 181 IRDTELAATMVELGKDKRNPDELAEALDERLGDFAFPDEFVFDVWGAIGDAK 232


>gi|42544146 regulator of G-protein signalling 19 interacting
           protein 1 isoform 2 [Homo sapiens]
          Length = 236

 Score =  322 bits (826), Expect = 2e-88
 Identities = 160/232 (68%), Positives = 191/232 (82%), Gaps = 2/232 (0%)

Query: 82  LYCTLNTPKIDMERLLGGQLGLEDFIFAHVKGIEKEVNVYKSEDSLGLTITDNGVGYAFI 141
           ++CTLNT K+DM++LLGGQ+GLEDFIFAHVKG  KEV V+KSED+LGLTITDNG GYAFI
Sbjct: 1   MFCTLNTHKVDMDKLLGGQIGLEDFIFAHVKGQRKEVEVFKSEDALGLTITDNGAGYAFI 60

Query: 142 KRIKDGGVIDSVKTICVGDHIESINGENIVGWRHYDVAKKLKELKKEELFTMKLIEPKKA 201
           KRIK+G VID +  I VGD IE+ING++++G RHY+VA+ LKEL +   FT+KL EP+KA
Sbjct: 61  KRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTLKLTEPRKA 120

Query: 202 FE-IELRSKAGK-SSGEKIGCGRATLRLRSKGPATVEEMPSETKAKAIEKIDDVLELYMG 259
           F+ I  RS  G+  SG ++G GR TLRLRS+GPATVE++PS  + KAIEK+DD+LE YMG
Sbjct: 121 FDMISQRSAGGRPGSGPQLGTGRGTLRLRSRGPATVEDLPSAFEEKAIEKVDDLLESYMG 180

Query: 260 IRDIDLATTMFEAGKDKVNPDEFAVALDETLGDFAFPDEFVFDVWGVIGDAK 311
           IRD +LA TM E GKDK NPDE A ALDE LGDFAFPDEFVFDVWG IGDAK
Sbjct: 181 IRDTELAATMVELGKDKRNPDELAEALDERLGDFAFPDEFVFDVWGAIGDAK 232


>gi|42544149 regulator of G-protein signalling 19 interacting
           protein 1 isoform 2 [Homo sapiens]
          Length = 236

 Score =  322 bits (826), Expect = 2e-88
 Identities = 160/232 (68%), Positives = 191/232 (82%), Gaps = 2/232 (0%)

Query: 82  LYCTLNTPKIDMERLLGGQLGLEDFIFAHVKGIEKEVNVYKSEDSLGLTITDNGVGYAFI 141
           ++CTLNT K+DM++LLGGQ+GLEDFIFAHVKG  KEV V+KSED+LGLTITDNG GYAFI
Sbjct: 1   MFCTLNTHKVDMDKLLGGQIGLEDFIFAHVKGQRKEVEVFKSEDALGLTITDNGAGYAFI 60

Query: 142 KRIKDGGVIDSVKTICVGDHIESINGENIVGWRHYDVAKKLKELKKEELFTMKLIEPKKA 201
           KRIK+G VID +  I VGD IE+ING++++G RHY+VA+ LKEL +   FT+KL EP+KA
Sbjct: 61  KRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTLKLTEPRKA 120

Query: 202 FE-IELRSKAGK-SSGEKIGCGRATLRLRSKGPATVEEMPSETKAKAIEKIDDVLELYMG 259
           F+ I  RS  G+  SG ++G GR TLRLRS+GPATVE++PS  + KAIEK+DD+LE YMG
Sbjct: 121 FDMISQRSAGGRPGSGPQLGTGRGTLRLRSRGPATVEDLPSAFEEKAIEKVDDLLESYMG 180

Query: 260 IRDIDLATTMFEAGKDKVNPDEFAVALDETLGDFAFPDEFVFDVWGVIGDAK 311
           IRD +LA TM E GKDK NPDE A ALDE LGDFAFPDEFVFDVWG IGDAK
Sbjct: 181 IRDTELAATMVELGKDKRNPDELAEALDERLGDFAFPDEFVFDVWGAIGDAK 232


>gi|186972120 calcium/calmodulin-dependent serine protein kinase
           isoform 1 [Homo sapiens]
          Length = 921

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 28/123 (22%), Positives = 57/123 (46%), Gaps = 8/123 (6%)

Query: 123 SEDSLGLTITDNGVGYAFIKRIKDGGVIDSVKTICVGDHIESINGENIVGWRHYDVAKKL 182
           +++ +G+T+  N + +  + RI  GG+I    T+ VGD I  ING ++       + K L
Sbjct: 497 TDEPMGITLKMNELNHCIVARIMHGGMIHRQGTLHVGDEIREINGISVANQTVEQLQKML 556

Query: 183 KELKKEELFTMKLIEPKKAFEIELRSKAGKSSGEKIGCGRATLRLRSKGPATVEEMPSET 242
           +E++     T K++   +         +  +S +    G ++         +V ++PS T
Sbjct: 557 REMRGS--ITFKIVPSYRTQSSSCERDSPSTSRQSPANGHSSTN------NSVSDLPSTT 608

Query: 243 KAK 245
           + K
Sbjct: 609 QPK 611


>gi|186700629 calcium/calmodulin-dependent serine protein kinase
           isoform 3 [Homo sapiens]
          Length = 897

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 19/64 (29%), Positives = 36/64 (56%)

Query: 123 SEDSLGLTITDNGVGYAFIKRIKDGGVIDSVKTICVGDHIESINGENIVGWRHYDVAKKL 182
           +++ +G+T+  N + +  + RI  GG+I    T+ VGD I  ING ++       + K L
Sbjct: 491 TDEPMGITLKMNELNHCIVARIMHGGMIHRQGTLHVGDEIREINGISVANQTVEQLQKML 550

Query: 183 KELK 186
           +E++
Sbjct: 551 REMR 554


>gi|186700627 calcium/calmodulin-dependent serine protein kinase
           isoform 2 [Homo sapiens]
          Length = 898

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 19/64 (29%), Positives = 36/64 (56%)

Query: 123 SEDSLGLTITDNGVGYAFIKRIKDGGVIDSVKTICVGDHIESINGENIVGWRHYDVAKKL 182
           +++ +G+T+  N + +  + RI  GG+I    T+ VGD I  ING ++       + K L
Sbjct: 497 TDEPMGITLKMNELNHCIVARIMHGGMIHRQGTLHVGDEIREINGISVANQTVEQLQKML 556

Query: 183 KELK 186
           +E++
Sbjct: 557 REMR 560


>gi|148746189 multiple PDZ domain protein [Homo sapiens]
          Length = 2041

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 39/143 (27%), Positives = 60/143 (41%), Gaps = 17/143 (11%)

Query: 111 VKGIEKEV---NVYKSEDSLGLTIT-DNGVGYAFIKRIKDGGVIDSVKTICVGDHIESIN 166
           + GI  E+   +V K  ++ GL I+ +  VG+ FI+ +   G +     +  GD +  +N
Sbjct: 544 IMGINYEIVVAHVSKFSENSGLGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELLEVN 603

Query: 167 GENIVGWRHYDVAKKLKELKKEELF----------TMKLIEPKKAFEIELRSKAGKSSGE 216
           G  ++G  H DV   LKEL  E             T   ++     +IEL  K     GE
Sbjct: 604 GITLLGENHQDVVNILKELPIEVTMVCCRRTVPPTTQSELDSLDLCDIELTEKPHVDLGE 663

Query: 217 KIGCGRA---TLRLRSKGPATVE 236
            IG        L +   G +T E
Sbjct: 664 FIGSSETEDPVLAMTDAGQSTEE 686



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 30/105 (28%), Positives = 49/105 (46%), Gaps = 4/105 (3%)

Query: 112  KGIEKEVNVYKSEDSLGLTITDNGVGYAFIKR-IKDGGVIDSVKTICVGDHIESINGENI 170
            +  E+ +N+ K   SLG+T++ N  G   I R I  GG I     I +GD I SIN E+ 
Sbjct: 1003 ESFERTINIAKGNSSLGMTVSANKDGLGMIVRSIIHGGAISRDGRIAIGDCILSINEEST 1062

Query: 171  VGWRHYDVAKKLKE---LKKEELFTMKLIEPKKAFEIELRSKAGK 212
            +   +      L+    +  +   T    E  + F+I L  ++G+
Sbjct: 1063 ISVTNAQARAMLRRHSLIGPDIKITYVPAEHLEEFKISLGQQSGR 1107



 Score = 37.7 bits (86), Expect = 0.013
 Identities = 29/112 (25%), Positives = 53/112 (47%), Gaps = 4/112 (3%)

Query: 122  KSEDSLGLTITDNG-VGYAFIKRIKDGGVIDSVKTICVGDHIESINGENIVGWRHYDVAK 180
            K +  LG+ I++   +    IK + + GV  +   + VGD I +++ E +VG   Y + K
Sbjct: 1488 KDQGGLGIAISEEDTLSGVIIKSLTEHGVAATDGRLKVGDQILAVDDEIVVG---YPIEK 1544

Query: 181  KLKELKKEELFTMKLIEPKKAFEIELRSKAGKSSGEKIGCGRATLRLRSKGP 232
             +  LK  ++     I  +      + S AG +SGEK    ++ +  +S  P
Sbjct: 1545 FISLLKTAKMTVKLTIHAENPDSQAVPSAAGAASGEKKNSSQSLMVPQSGSP 1596



 Score = 34.7 bits (78), Expect = 0.11
 Identities = 19/67 (28%), Positives = 28/67 (41%)

Query: 118 VNVYKSEDSLGLTITDNGVGYAFIKRIKDGGVIDSVKTICVGDHIESINGENIVGWRHYD 177
           + +      LG  I         +K I  GGV D    +C GDHI  I   ++ G     
Sbjct: 258 IELVNDGSGLGFGIIGGKATGVIVKTILPGGVADQHGRLCSGDHILKIGDTDLAGMSSEQ 317

Query: 178 VAKKLKE 184
           VA+ L++
Sbjct: 318 VAQVLRQ 324



 Score = 33.5 bits (75), Expect = 0.25
 Identities = 29/116 (25%), Positives = 49/116 (42%), Gaps = 17/116 (14%)

Query: 112 KGIEKE---VNVYKSEDSLGLTITDNGVGYA----------FIKRIKDGGVIDSVKTICV 158
           KG E E   V + K+   LG+TI     GY           F+K I     ++    I +
Sbjct: 369 KGEESETFDVELTKNVQGLGITIA----GYIGDKKLEPSGIFVKSITKSSAVEHDGRIQI 424

Query: 159 GDHIESINGENIVGWRHYDVAKKLKELKKEELFTMKLIEPKKAFEIELRSKAGKSS 214
           GD I +++G N+ G+ +    + L+   +  L T+     K+  E+  R    K +
Sbjct: 425 GDQIIAVDGTNLQGFTNQQAVEVLRHTGQTVLLTLMRRGMKQEAELMSREDVTKDA 480



 Score = 32.7 bits (73), Expect = 0.43
 Identities = 34/116 (29%), Positives = 48/116 (41%), Gaps = 11/116 (9%)

Query: 122  KSEDSLGLTIT----DNGVGYAFIKRIKDGGVIDSVKTICVGDHIESINGENIVGWRHYD 177
            K    LGL+I     D GV   F+  I  GG+ D+   +  GD I  +NGE++       
Sbjct: 1731 KPGKGLGLSIVGKRNDTGV---FVSDIVKGGIADADGRLMQGDQILMVNGEDVRNATQEA 1787

Query: 178  VAKKLKELKKE-ELFTMKLIEPKKAFEIELRSKAGKSSGEKIGCGRATLRLRSKGP 232
            VA  LK  +     FT  L     +  +E  SK    + E  G     ++   KGP
Sbjct: 1788 VAALLKVSEGSLSSFTFPLSGSSTSESLESSSKKNALASEIQGLRTVEMK---KGP 1840


>gi|87196343 PDZ domain containing 2 [Homo sapiens]
          Length = 2839

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 25/73 (34%), Positives = 36/73 (49%), Gaps = 5/73 (6%)

Query: 118  VNVYKSEDSLGLTITDN-----GVGYAFIKRIKDGGVIDSVKTICVGDHIESINGENIVG 172
            V V K+   LGL++        G G   IKR+  GG  +    I  GD I +ING+ +VG
Sbjct: 2751 VEVLKTSAGLGLSLDGGKSSVTGDGPLVIKRVYKGGAAEQAGIIEAGDEILAINGKPLVG 2810

Query: 173  WRHYDVAKKLKEL 185
              H+D    +K +
Sbjct: 2811 LMHFDAWNIMKSV 2823



 Score = 28.9 bits (63), Expect = 6.2
 Identities = 18/73 (24%), Positives = 34/73 (46%), Gaps = 7/73 (9%)

Query: 117 EVNVYKSEDSLGLTITDNGVGYA------FIKRIKDGGVIDSVKTICVGDHIESINGENI 170
           ++ + K  D LG+ ++  G G         + ++K+GG       + +GD +  ING  +
Sbjct: 334 KMELLKESDGLGIQVS-GGRGSKRSPHAIVVTQVKEGGAAHRDGRLSLGDELLVINGHLL 392

Query: 171 VGWRHYDVAKKLK 183
           VG  H +    L+
Sbjct: 393 VGLSHEEAVAILR 405



 Score = 28.9 bits (63), Expect = 6.2
 Identities = 21/76 (27%), Positives = 37/76 (48%), Gaps = 4/76 (5%)

Query: 141  IKRIKDGGVIDSVKTICVGDHIESINGENIVGWRHYDVAKKL--KELKKEELFTMK--LI 196
            + R+   G      T+  GD + S+NG ++ G  H +V K L   +L K+ L  +K  + 
Sbjct: 2650 VHRVFSQGAASQEGTMNRGDFLLSVNGASLAGLAHGNVLKVLHQAQLHKDALVVIKKGMD 2709

Query: 197  EPKKAFEIELRSKAGK 212
            +P+ +   E  +  GK
Sbjct: 2710 QPRPSARQEPPTANGK 2725


>gi|4507137 acidic alpha 1 syntrophin [Homo sapiens]
          Length = 505

 Score = 39.3 bits (90), Expect = 0.005
 Identities = 35/154 (22%), Positives = 65/154 (42%), Gaps = 11/154 (7%)

Query: 141 IKRIKDGGVIDSVKTICVGDHIESINGENIVGWRHYDVAKKLKELKKEELFTMKLIEPKK 200
           I +I  G   D  + + VGD I S+NGE++    H +  + LK+  KE +  +K ++   
Sbjct: 114 ISKIFKGLAADQTEALFVGDAILSVNGEDLSSATHDEAVQVLKKTGKEVVLEVKYMKDVS 173

Query: 201 AFEIELRSKAGKSSGEKIGCGRATLRLRSKGPATVEEMPSETKAKAIEKI--------DD 252
            +    ++  G +S        + L+ +   P       SE K  +++          +D
Sbjct: 174 PY---FKNSTGGTSVGWDSPPASPLQRQPSSPGPTPRNFSEAKHMSLKMAYVSKRCTPND 230

Query: 253 VLELYMGIRDIDLATTMFEAGKDKVNPDEFAVAL 286
               Y+ I   D   T+F   KD+ +   +A A+
Sbjct: 231 PEPRYLEICSADGQDTLFLRAKDEASARSWATAI 264


>gi|93204861 protein phosphatase 1, regulatory (inhibitor) subunit
           9A [Homo sapiens]
          Length = 1098

 Score = 38.9 bits (89), Expect = 0.006
 Identities = 27/95 (28%), Positives = 42/95 (44%), Gaps = 8/95 (8%)

Query: 118 VNVYKSEDSLGLTITDNGVGY--------AFIKRIKDGGVIDSVKTICVGDHIESINGEN 169
           V + K ED LG++I   GVG          F+K + +GG       I V D I  ++G +
Sbjct: 505 VELEKDEDGLGISIIGMGVGADAGLEKLGIFVKTVTEGGAAQRDGRIQVNDQIVEVDGIS 564

Query: 170 IVGWRHYDVAKKLKELKKEELFTMKLIEPKKAFEI 204
           +VG      A  L+  K    F +   +P +  E+
Sbjct: 565 LVGVTQNFAATVLRNTKGNVRFVIGREKPGQVSEV 599


>gi|4505237 palmitoylated membrane protein 1 [Homo sapiens]
          Length = 466

 Score = 38.5 bits (88), Expect = 0.008
 Identities = 27/83 (32%), Positives = 43/83 (51%), Gaps = 5/83 (6%)

Query: 109 AHVKGIE-KEVNVYK----SEDSLGLTITDNGVGYAFIKRIKDGGVIDSVKTICVGDHIE 163
           A VKG E ++V + +    +E+ +G+T+  N      + RI  GG+I    ++ VGD I 
Sbjct: 59  AQVKGQEVRKVRLIQFEKVTEEPMGITLKLNEKQSCTVARILHGGMIHRQGSLHVGDEIL 118

Query: 164 SINGENIVGWRHYDVAKKLKELK 186
            ING N+       + K +KE K
Sbjct: 119 EINGTNVTNHSVDQLQKAMKETK 141


>gi|27436957 membrane associated guanylate kinase, WW and PDZ domain
            containing 2 [Homo sapiens]
          Length = 1455

 Score = 38.5 bits (88), Expect = 0.008
 Identities = 25/77 (32%), Positives = 38/77 (49%), Gaps = 7/77 (9%)

Query: 141  IKRIKDGGVIDSVKTICVGDHIESINGENIVGWRHYDVAKKLKELKKEELFTMKLIEPKK 200
            I RI DG   D    + VGD I ++NG++I+   H D+ K +K+       T+++I  + 
Sbjct: 954  IGRIIDGSPADRCAKLKVGDRILAVNGQSIINMPHADIVKLIKDAGLS--VTLRIIPQE- 1010

Query: 201  AFEIELRSKAGKSSGEK 217
                EL S     S EK
Sbjct: 1011 ----ELNSPTSAPSSEK 1023



 Score = 33.5 bits (75), Expect = 0.25
 Identities = 21/67 (31%), Positives = 31/67 (46%), Gaps = 4/67 (5%)

Query: 118 VNVYKSEDSLGLTITDNGVGYAFIKRIKDGGVIDSVKTICVGDHIESINGENIVGWRHYD 177
           + + K     G TI D+  G   +K+I D   I     +C GD I  IN +N+    H +
Sbjct: 606 LTIVKGAQGFGFTIADSPTGQR-VKQILD---IQGCPGLCEGDLIVEINQQNVQNLSHTE 661

Query: 178 VAKKLKE 184
           V   LK+
Sbjct: 662 VVDILKD 668


>gi|223890252 glutamate receptor interacting protein 1 [Homo
           sapiens]
          Length = 1076

 Score = 38.1 bits (87), Expect = 0.010
 Identities = 20/67 (29%), Positives = 38/67 (56%), Gaps = 4/67 (5%)

Query: 122 KSEDSLGLTITDNGV---GYAFIKRIKDGGVIDSVKTICVGDHIESINGENIVGWRHYDV 178
           K   +LGLT++  G+   G   +  ++ GG+      + VGD+I+++NG N+  +RH ++
Sbjct: 59  KEGTTLGLTVS-GGIDKDGKPRVSNLRQGGIAARSDQLDVGDYIKAVNGINLAKFRHDEI 117

Query: 179 AKKLKEL 185
              LK +
Sbjct: 118 ISLLKNV 124



 Score = 32.7 bits (73), Expect = 0.43
 Identities = 29/138 (21%), Positives = 57/138 (41%), Gaps = 10/138 (7%)

Query: 117 EVNVYKSEDSLGLTITD------NGVGYAFIKRIKDGGVIDSVKTICVGDHIESINGENI 170
           EV ++K  ++ G  I        N      I  ++ GG  D   TI  GD + S++G  +
Sbjct: 152 EVTLHKEGNTFGFVIRGGAHDDRNKSRPVVITCVRPGGPADREGTIKPGDRLLSVDGIRL 211

Query: 171 VGWRHYDVAKKLKELKKEEL----FTMKLIEPKKAFEIELRSKAGKSSGEKIGCGRATLR 226
           +G  H +    LK+  +E      + + +++        L  +  K+ G  +G    T  
Sbjct: 212 LGTTHAEAMSILKQCGQEAALLIEYDVSVMDSVATASGPLLVEVAKTPGASLGVALTTSM 271

Query: 227 LRSKGPATVEEMPSETKA 244
             +K    ++++ S + A
Sbjct: 272 CCNKQVIVIDKIKSASIA 289


>gi|111154074 palmitoylated membrane protein 7 [Homo sapiens]
          Length = 576

 Score = 38.1 bits (87), Expect = 0.010
 Identities = 30/98 (30%), Positives = 44/98 (44%), Gaps = 6/98 (6%)

Query: 116 KEVNVYKSEDSLGLTIT-DNGVGYAFIKRIKDGGVIDSVKTICVGDHIESINGENIVGWR 174
           K + + K+ + LG TI  D   G   + RI  GG  D    I VGD +  +NG  +   R
Sbjct: 138 KIIRLVKNREPLGATIKKDEQTGAIIVARIMRGGAADRSGLIHVGDELREVNGIPVEDKR 197

Query: 175 HYDVAKKLKELKKEELFTMKLIEPKKAFEIELRSKAGK 212
             ++ + L +   +   T K+I   K    E  SK GK
Sbjct: 198 PEEIIQILAQ--SQGAITFKIIPGSKE---ETPSKEGK 230


>gi|88758603 protein interacting with C kinase 1 [Homo sapiens]
          Length = 415

 Score = 37.7 bits (86), Expect = 0.013
 Identities = 31/119 (26%), Positives = 54/119 (45%), Gaps = 24/119 (20%)

Query: 155 TICVGDHIESINGENIVGWRHYDVAKKLKELKKEEL--FTMKLIEPKKAFEIELRSKAGK 212
           T+  GD I  +NG +I G    +VAK ++E+K E    +     +PK+   +++  K  K
Sbjct: 63  TVAAGDEITGVNGRSIKGKTKVEVAKMIQEVKGEVTIHYNKLQADPKQGMSLDIVLKKVK 122

Query: 213 -------SSG--EKIGCGRATLRLRSKGPATVEEMPSETKAKAIEKIDDVLELYMGIRD 262
                  SSG  + +G  RA L              ++   K +E+++   ELY G+ +
Sbjct: 123 HRLVENMSSGTADALGLSRAIL-------------CNDGLVKRLEELERTAELYKGMTE 168


>gi|88758600 protein interacting with C kinase 1 [Homo sapiens]
          Length = 415

 Score = 37.7 bits (86), Expect = 0.013
 Identities = 31/119 (26%), Positives = 54/119 (45%), Gaps = 24/119 (20%)

Query: 155 TICVGDHIESINGENIVGWRHYDVAKKLKELKKEEL--FTMKLIEPKKAFEIELRSKAGK 212
           T+  GD I  +NG +I G    +VAK ++E+K E    +     +PK+   +++  K  K
Sbjct: 63  TVAAGDEITGVNGRSIKGKTKVEVAKMIQEVKGEVTIHYNKLQADPKQGMSLDIVLKKVK 122

Query: 213 -------SSG--EKIGCGRATLRLRSKGPATVEEMPSETKAKAIEKIDDVLELYMGIRD 262
                  SSG  + +G  RA L              ++   K +E+++   ELY G+ +
Sbjct: 123 HRLVENMSSGTADALGLSRAIL-------------CNDGLVKRLEELERTAELYKGMTE 168


>gi|7110697 protein interacting with C kinase 1 [Homo sapiens]
          Length = 415

 Score = 37.7 bits (86), Expect = 0.013
 Identities = 31/119 (26%), Positives = 54/119 (45%), Gaps = 24/119 (20%)

Query: 155 TICVGDHIESINGENIVGWRHYDVAKKLKELKKEEL--FTMKLIEPKKAFEIELRSKAGK 212
           T+  GD I  +NG +I G    +VAK ++E+K E    +     +PK+   +++  K  K
Sbjct: 63  TVAAGDEITGVNGRSIKGKTKVEVAKMIQEVKGEVTIHYNKLQADPKQGMSLDIVLKKVK 122

Query: 213 -------SSG--EKIGCGRATLRLRSKGPATVEEMPSETKAKAIEKIDDVLELYMGIRD 262
                  SSG  + +G  RA L              ++   K +E+++   ELY G+ +
Sbjct: 123 HRLVENMSSGTADALGLSRAIL-------------CNDGLVKRLEELERTAELYKGMTE 168


>gi|218156340 chapsyn-110 isoform 3 [Homo sapiens]
          Length = 749

 Score = 36.6 bits (83), Expect = 0.030
 Identities = 35/138 (25%), Positives = 56/138 (40%), Gaps = 4/138 (2%)

Query: 111 VKGIEKEVNVYKSEDSLGLTIT--DNGVGYAFIKRIKDGGVIDSVKTICVGDHIESINGE 168
           ++G  ++V ++K    LG  I   ++G G  F+  I  GG  D    +  GD I S+NG 
Sbjct: 312 LEGEPRKVVLHKGSTGLGFNIVGGEDGEGI-FVSFILAGGPADLSGELQRGDQILSVNGI 370

Query: 169 NIVGWRHYDVAKKLKEL-KKEELFTMKLIEPKKAFEIELRSKAGKSSGEKIGCGRATLRL 227
           ++ G  H   A  LK   +   +      E    FE ++     +     +  G  +LR 
Sbjct: 371 DLRGASHEQAAAALKGAGQTVTIIAQYQPEDYARFEAKIHDLREQMMNHSMSSGSGSLRT 430

Query: 228 RSKGPATVEEMPSETKAK 245
             K    V  M    K+K
Sbjct: 431 NQKRSLYVRAMFDYDKSK 448


>gi|218156338 chapsyn-110 isoform 1 [Homo sapiens]
          Length = 975

 Score = 36.6 bits (83), Expect = 0.030
 Identities = 35/138 (25%), Positives = 56/138 (40%), Gaps = 4/138 (2%)

Query: 111 VKGIEKEVNVYKSEDSLGLTIT--DNGVGYAFIKRIKDGGVIDSVKTICVGDHIESINGE 168
           ++G  ++V ++K    LG  I   ++G G  F+  I  GG  D    +  GD I S+NG 
Sbjct: 520 LEGEPRKVVLHKGSTGLGFNIVGGEDGEGI-FVSFILAGGPADLSGELQRGDQILSVNGI 578

Query: 169 NIVGWRHYDVAKKLKEL-KKEELFTMKLIEPKKAFEIELRSKAGKSSGEKIGCGRATLRL 227
           ++ G  H   A  LK   +   +      E    FE ++     +     +  G  +LR 
Sbjct: 579 DLRGASHEQAAAALKGAGQTVTIIAQYQPEDYARFEAKIHDLREQMMNHSMSSGSGSLRT 638

Query: 228 RSKGPATVEEMPSETKAK 245
             K    V  M    K+K
Sbjct: 639 NQKRSLYVRAMFDYDKSK 656


>gi|91199538 chapsyn-110 isoform 2 [Homo sapiens]
          Length = 870

 Score = 36.6 bits (83), Expect = 0.030
 Identities = 35/138 (25%), Positives = 56/138 (40%), Gaps = 4/138 (2%)

Query: 111 VKGIEKEVNVYKSEDSLGLTIT--DNGVGYAFIKRIKDGGVIDSVKTICVGDHIESINGE 168
           ++G  ++V ++K    LG  I   ++G G  F+  I  GG  D    +  GD I S+NG 
Sbjct: 415 LEGEPRKVVLHKGSTGLGFNIVGGEDGEGI-FVSFILAGGPADLSGELQRGDQILSVNGI 473

Query: 169 NIVGWRHYDVAKKLKEL-KKEELFTMKLIEPKKAFEIELRSKAGKSSGEKIGCGRATLRL 227
           ++ G  H   A  LK   +   +      E    FE ++     +     +  G  +LR 
Sbjct: 474 DLRGASHEQAAAALKGAGQTVTIIAQYQPEDYARFEAKIHDLREQMMNHSMSSGSGSLRT 533

Query: 228 RSKGPATVEEMPSETKAK 245
             K    V  M    K+K
Sbjct: 534 NQKRSLYVRAMFDYDKSK 551


>gi|122937249 glutamate receptor interacting protein 2 [Homo
           sapiens]
          Length = 1141

 Score = 36.6 bits (83), Expect = 0.030
 Identities = 26/95 (27%), Positives = 46/95 (48%), Gaps = 4/95 (4%)

Query: 112 KGIEKEVNVYKSEDSLGLTI---TDNGVGYAFIKRIKDGGVIDSVKTICVGDHIESINGE 168
           +GI     + K   +LGLTI   TD   G   +  ++ GG+      + +GD+I S+NG 
Sbjct: 141 RGITVVELIKKEGSTLGLTISGGTDKD-GKPRVSNLRPGGLAARSDLLNIGDYIRSVNGI 199

Query: 169 NIVGWRHYDVAKKLKELKKEELFTMKLIEPKKAFE 203
           ++   RH ++   LK + +  +  ++   P  A E
Sbjct: 200 HLTRLRHDEIITLLKNVGERVVLEVEYELPPPAPE 234



 Score = 35.8 bits (81), Expect = 0.051
 Identities = 30/132 (22%), Positives = 55/132 (41%), Gaps = 10/132 (7%)

Query: 117 EVNVYKSEDSLGLTITDNGVGYAFIKR------IKDGGVIDSVKTICVGDHIESINGENI 170
           +V++YK  +S G  +           R      ++ GG  D   ++ VGD + S++G  +
Sbjct: 245 DVSLYKEGNSFGFVLRGGAHEDGHKSRPLVLTYVRPGGPADREGSLKVGDRLLSVDGIPL 304

Query: 171 VGWRHYDVAKKLKELKKEELFTMK--LIEPKKAFEIE--LRSKAGKSSGEKIGCGRATLR 226
            G  H      L++   E LF ++  +  P         L  +  K+ G  +G    T  
Sbjct: 305 HGASHATALATLRQCSHEALFQVEYDVATPDTVANASGPLMVEIVKTPGSALGISLTTTS 364

Query: 227 LRSKGPATVEEM 238
           LR+K   T++ +
Sbjct: 365 LRNKSVITIDRI 376



 Score = 28.9 bits (63), Expect = 6.2
 Identities = 21/75 (28%), Positives = 36/75 (48%), Gaps = 4/75 (5%)

Query: 118 VNVYKSEDS-LGLTITDNGV---GYAFIKRIKDGGVIDSVKTICVGDHIESINGENIVGW 173
           V + K+  S LG+++T   +       I RIK   V+D    +  GDHI SI+G ++   
Sbjct: 346 VEIVKTPGSALGISLTTTSLRNKSVITIDRIKPASVVDRSGALHPGDHILSIDGTSMEHC 405

Query: 174 RHYDVAKKLKELKKE 188
              +  K L  + ++
Sbjct: 406 SLLEATKLLASISEK 420


>gi|112382257 InaD-like [Homo sapiens]
          Length = 1801

 Score = 36.2 bits (82), Expect = 0.039
 Identities = 24/64 (37%), Positives = 32/64 (50%), Gaps = 5/64 (7%)

Query: 125  DSLGLTITDN-----GVGYAFIKRIKDGGVIDSVKTICVGDHIESINGENIVGWRHYDVA 179
            D+LG++I        G    FI  I+  GV    + + VGD I SING+ + G  H DV 
Sbjct: 1685 DALGISIAGGRGSPLGDIPVFIAMIQASGVAARTQKLKVGDRIVSINGQPLDGLSHADVV 1744

Query: 180  KKLK 183
              LK
Sbjct: 1745 NLLK 1748



 Score = 35.4 bits (80), Expect = 0.066
 Identities = 21/71 (29%), Positives = 30/71 (42%)

Query: 113 GIEKEVNVYKSEDSLGLTITDNGVGYAFIKRIKDGGVIDSVKTICVGDHIESINGENIVG 172
           G  +EV +      LG  I         ++ I  GG+ D    +  GDHI  I G N+ G
Sbjct: 244 GHVEEVELINDGSGLGFGIVGGKTSGVVVRTIVPGGLADRDGRLQTGDHILKIGGTNVQG 303

Query: 173 WRHYDVAKKLK 183
                VA+ L+
Sbjct: 304 MTSEQVAQVLR 314



 Score = 31.6 bits (70), Expect = 0.96
 Identities = 25/64 (39%), Positives = 31/64 (48%), Gaps = 3/64 (4%)

Query: 122  KSEDSLGLTITD--NGVGYAFIKRIKDGGVIDSVKTICVGDHIESINGENIVGWRHYDVA 179
            K+   LGL+I    NG G  FI  I  GG  D    +  GD I S+NGE++       VA
Sbjct: 1539 KAGRGLGLSIVGKRNGSG-VFISDIVKGGAADLDGRLIQGDQILSVNGEDMRNASQETVA 1597

Query: 180  KKLK 183
              LK
Sbjct: 1598 TILK 1601



 Score = 28.5 bits (62), Expect = 8.1
 Identities = 16/59 (27%), Positives = 30/59 (50%), Gaps = 1/59 (1%)

Query: 127 LGLTITDNGVGYAFIKRIKDGGVIDSVKTICVGDHIESINGENIVGWRHYDVAKKLKEL 185
           LG+ + D+  G+ +I  I  GG +D++  +   D +  +NG  + G    +    LKE+
Sbjct: 570 LGVEV-DSFDGHHYISSIVSGGPVDTLGLLQPEDELLEVNGMQLYGKSRREAVSFLKEV 627


>gi|21536464 palmitoylated membrane protein 3 [Homo sapiens]
          Length = 585

 Score = 36.2 bits (82), Expect = 0.039
 Identities = 24/82 (29%), Positives = 42/82 (51%), Gaps = 3/82 (3%)

Query: 116 KEVNVYKSEDSLGLTIT-DNGVGYAFIKRIKDGGVIDSVKTICVGDHIESINGENIVGWR 174
           K V + K+++ LG TI  D   G   + RI  GG  D    + VGD +  +NG  ++  R
Sbjct: 136 KIVRLVKNKEPLGATIRRDEHSGAVVVARIMRGGAADRSGLVHVGDELREVNGIAVLHKR 195

Query: 175 HYDVAKKLKELKKEELFTMKLI 196
             ++++ L +   +   T+K+I
Sbjct: 196 PDEISQILAQ--SQGSITLKII 215


>gi|148833504 interleukin 16 isoform 2 [Homo sapiens]
          Length = 1332

 Score = 35.8 bits (81), Expect = 0.051
 Identities = 17/48 (35%), Positives = 26/48 (54%)

Query: 140 FIKRIKDGGVIDSVKTICVGDHIESINGENIVGWRHYDVAKKLKELKK 187
           ++K I  GG   +   +  GD I  +NGE++ G  H D  +K K+ KK
Sbjct: 245 YVKTIFAGGAAAADGRLQEGDEILELNGESMAGLTHQDALQKFKQAKK 292



 Score = 31.6 bits (70), Expect = 0.96
 Identities = 31/128 (24%), Positives = 54/128 (42%), Gaps = 24/128 (18%)

Query: 92   DMERLLGGQLGLEDFIFAHVKGIEKEVNVY-----KSEDSLGLTIT--DNGVGYAF---- 140
            D   L  GQ  +       +K + +EV V      K  D + +TI   + G G  F    
Sbjct: 1071 DHSSLQSGQSVISLLSSEELKKLIEEVKVLDEATLKQLDGIHVTILHKEEGAGLGFSLAG 1130

Query: 141  ----------IKRIKDGGVIDSVKTICVGDHIESINGENIVGWRHYD---VAKKLKELKK 187
                      + R+   G+     TI  G+ + SING+++ G  H+D   + ++ +E ++
Sbjct: 1131 GADLENKVITVHRVFPNGLASQEGTIQKGNEVLSINGKSLKGTTHHDALAILRQAREPRQ 1190

Query: 188  EELFTMKL 195
              + T KL
Sbjct: 1191 AVIVTRKL 1198


>gi|218505835 membrane-associated guanylate kinase-related  3
           isoform 1 [Homo sapiens]
          Length = 1481

 Score = 35.8 bits (81), Expect = 0.051
 Identities = 29/117 (24%), Positives = 46/117 (39%), Gaps = 10/117 (8%)

Query: 141 IKRIKDGGVIDSVKTICVGDHIESINGENIVGWRHYDVAKKLKELKKEELFTMKLIEPKK 200
           I R+ +G   D    + VGDHI ++NG++IV   H ++ + +K+       T+       
Sbjct: 882 IGRVIEGSPADRCGKLKVGDHISAVNGQSIVELSHDNIVQLIKDAGVTVTLTV------- 934

Query: 201 AFEIELRSKAGKSSGEKIGCGRATLRLRSKGPATVEEMPSETKAKAIEKIDDVLELY 257
              I      G  SG         L+ R  G +    +P +  A   E   DV   Y
Sbjct: 935 ---IAEEEHHGPPSGTNSARQSPALQHRPMGQSQANHIPGDRSALEGEIGKDVSTSY 988



 Score = 30.8 bits (68), Expect = 1.6
 Identities = 24/75 (32%), Positives = 35/75 (46%), Gaps = 4/75 (5%)

Query: 109 AHVKGIEKEVNVYKSEDSLGLTIT--DNGVGYAFIKRI-KDGGVIDSVKTICVGDHIESI 165
           + +KG+    ++ KS    G TI   D    +  +K + KDG      K I  GD I  I
Sbjct: 402 SQLKGVLVRASLKKSTMGFGFTIIGGDRPDEFLQVKNVLKDGPAAQDGK-IAPGDVIVDI 460

Query: 166 NGENIVGWRHYDVAK 180
           NG  ++G  H DV +
Sbjct: 461 NGNCVLGHTHADVVQ 475


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.137    0.388 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,362,505
Number of Sequences: 37866
Number of extensions: 494368
Number of successful extensions: 1826
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 58
Number of HSP's successfully gapped in prelim test: 51
Number of HSP's that attempted gapping in prelim test: 1679
Number of HSP's gapped (non-prelim): 191
length of query: 315
length of database: 18,247,518
effective HSP length: 102
effective length of query: 213
effective length of database: 14,385,186
effective search space: 3064044618
effective search space used: 3064044618
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press