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Search of human proteins with 41352061
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|41352061 metalloprotease 1 [Homo sapiens]
(1037 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|41352061 metalloprotease 1 [Homo sapiens] 2126 0.0
gi|155969707 insulin-degrading enzyme [Homo sapiens] 38 0.057
gi|56119110 family with sequence similarity 13, member A1 isofor... 38 0.057
gi|62865869 family with sequence similarity 13, member A1 isofor... 38 0.057
gi|156071452 nardilysin isoform b [Homo sapiens] 36 0.16
gi|156071450 nardilysin isoform a [Homo sapiens] 36 0.16
gi|83367077 mucin 16 [Homo sapiens] 35 0.28
gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens] 35 0.37
gi|239756691 PREDICTED: hypothetical protein [Homo sapiens] 33 1.8
gi|239751188 PREDICTED: hypothetical protein XP_002347742 [Homo ... 33 1.8
gi|239745676 PREDICTED: hypothetical protein XP_002343540 [Homo ... 33 1.8
gi|145580621 B and T lymphocyte associated isoform 1 [Homo sapiens] 33 1.8
gi|114155142 nuclear pore complex-associated protein TPR [Homo s... 32 2.4
gi|40316946 ADP-ribosylhydrolase like 1 isoform 2 [Homo sapiens] 32 2.4
gi|21702735 ADP-ribosylhydrolase like 1 isoform 1 [Homo sapiens] 32 2.4
gi|242332527 hypothetical protein LOC65250 [Homo sapiens] 32 4.1
gi|58530876 melanoma antigen family C, 1 [Homo sapiens] 32 4.1
gi|102468717 mediator complex subunit 13 [Homo sapiens] 32 4.1
gi|95147555 microtubule-associated protein 1A [Homo sapiens] 31 5.3
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 31 5.3
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 31 5.3
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 31 5.3
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 31 5.3
gi|94680976 coiled-coil domain containing 112 isoform 1 [Homo sa... 31 5.3
gi|145580595 coiled-coil domain containing 112 isoform 2 [Homo s... 31 5.3
gi|226437579 NAC alpha domain containing [Homo sapiens] 31 6.9
gi|239754540 PREDICTED: NAC alpha domain containing [Homo sapiens] 31 6.9
gi|239749105 PREDICTED: NAC alpha domain containing [Homo sapiens] 31 6.9
gi|239743134 PREDICTED: NAC alpha domain containing [Homo sapiens] 31 6.9
gi|239508792 PREDICTED: NAC alpha domain containing [Homo sapiens] 31 6.9
>gi|41352061 metalloprotease 1 [Homo sapiens]
Length = 1037
Score = 2126 bits (5509), Expect = 0.0
Identities = 1037/1037 (100%), Positives = 1037/1037 (100%)
Query: 1 MWRCGGRQGLCVLRRLSGGHAHHRAWRWNSNRACERALQYKLGDKIHGFTVNQVTSVPEL 60
MWRCGGRQGLCVLRRLSGGHAHHRAWRWNSNRACERALQYKLGDKIHGFTVNQVTSVPEL
Sbjct: 1 MWRCGGRQGLCVLRRLSGGHAHHRAWRWNSNRACERALQYKLGDKIHGFTVNQVTSVPEL 60
Query: 61 FLTAVKLTHDDTGARYLHLAREDTNNLFSVQFRTTPMDSTGVPHILEHTVLCGSQKYPCR 120
FLTAVKLTHDDTGARYLHLAREDTNNLFSVQFRTTPMDSTGVPHILEHTVLCGSQKYPCR
Sbjct: 61 FLTAVKLTHDDTGARYLHLAREDTNNLFSVQFRTTPMDSTGVPHILEHTVLCGSQKYPCR 120
Query: 121 DPFFKMLNRSLSTFMNAFTASDYTLYPFSTQNPKDFQNLLSVYLDATFFPCLRELDFWQE 180
DPFFKMLNRSLSTFMNAFTASDYTLYPFSTQNPKDFQNLLSVYLDATFFPCLRELDFWQE
Sbjct: 121 DPFFKMLNRSLSTFMNAFTASDYTLYPFSTQNPKDFQNLLSVYLDATFFPCLRELDFWQE 180
Query: 181 GWRLEHENPSDPQTPLVFKGVVFNEMKGAFTDNERIFSQHLQNRLLPDHTYSVVSGGDPL 240
GWRLEHENPSDPQTPLVFKGVVFNEMKGAFTDNERIFSQHLQNRLLPDHTYSVVSGGDPL
Sbjct: 181 GWRLEHENPSDPQTPLVFKGVVFNEMKGAFTDNERIFSQHLQNRLLPDHTYSVVSGGDPL 240
Query: 241 CIPELTWEQLKQFHATHYHPSNARFFTYGNFPLEQHLKQIHEEALSKFQKIEPSTVVPAQ 300
CIPELTWEQLKQFHATHYHPSNARFFTYGNFPLEQHLKQIHEEALSKFQKIEPSTVVPAQ
Sbjct: 241 CIPELTWEQLKQFHATHYHPSNARFFTYGNFPLEQHLKQIHEEALSKFQKIEPSTVVPAQ 300
Query: 301 TPWDKPREFQITCGPDSFATDPSKQTTISVSFLLPDITDTFEAFTLSLLSSLLTSGPNSP 360
TPWDKPREFQITCGPDSFATDPSKQTTISVSFLLPDITDTFEAFTLSLLSSLLTSGPNSP
Sbjct: 301 TPWDKPREFQITCGPDSFATDPSKQTTISVSFLLPDITDTFEAFTLSLLSSLLTSGPNSP 360
Query: 361 FYKALIESGLGTDFSPDVGYNGYTREAYFSVGLQGIAEKDIETVRSLIDRTIDEVVEKGF 420
FYKALIESGLGTDFSPDVGYNGYTREAYFSVGLQGIAEKDIETVRSLIDRTIDEVVEKGF
Sbjct: 361 FYKALIESGLGTDFSPDVGYNGYTREAYFSVGLQGIAEKDIETVRSLIDRTIDEVVEKGF 420
Query: 421 EDDRIEALLHKIEIQMKHQSTSFGLMLTSYIASCWNHDGDPVELLKLGNQLAKFRQCLQE 480
EDDRIEALLHKIEIQMKHQSTSFGLMLTSYIASCWNHDGDPVELLKLGNQLAKFRQCLQE
Sbjct: 421 EDDRIEALLHKIEIQMKHQSTSFGLMLTSYIASCWNHDGDPVELLKLGNQLAKFRQCLQE 480
Query: 481 NPKFLQEKVKQYFKNNQHKLTLSMRPDDKYHEKQAQVEATKLKQKVEALSPGDRQQIYEK 540
NPKFLQEKVKQYFKNNQHKLTLSMRPDDKYHEKQAQVEATKLKQKVEALSPGDRQQIYEK
Sbjct: 481 NPKFLQEKVKQYFKNNQHKLTLSMRPDDKYHEKQAQVEATKLKQKVEALSPGDRQQIYEK 540
Query: 541 GLELRSQQSKPQDASCLPALKVSDIEPTIPVTELDVVLTAGDIPVQYCAQPTNGMVYFRA 600
GLELRSQQSKPQDASCLPALKVSDIEPTIPVTELDVVLTAGDIPVQYCAQPTNGMVYFRA
Sbjct: 541 GLELRSQQSKPQDASCLPALKVSDIEPTIPVTELDVVLTAGDIPVQYCAQPTNGMVYFRA 600
Query: 601 FSSLNTLPEELRPYVPLFCSVLTKLGCGLLDYREQAQQIELKTGGMSASPHVLPDDSHMD 660
FSSLNTLPEELRPYVPLFCSVLTKLGCGLLDYREQAQQIELKTGGMSASPHVLPDDSHMD
Sbjct: 601 FSSLNTLPEELRPYVPLFCSVLTKLGCGLLDYREQAQQIELKTGGMSASPHVLPDDSHMD 660
Query: 661 TYEQGVLFSSLCLDRNLPDMMQLWSEIFNNPCFEEEEHFKVLVKMTAQELANGIPDSGHL 720
TYEQGVLFSSLCLDRNLPDMMQLWSEIFNNPCFEEEEHFKVLVKMTAQELANGIPDSGHL
Sbjct: 661 TYEQGVLFSSLCLDRNLPDMMQLWSEIFNNPCFEEEEHFKVLVKMTAQELANGIPDSGHL 720
Query: 721 YASIRAGRTLTPAGDLQETFSGMDQVRLMKRIAEMTDIKPILRKLPRIKKHLLNGDNMRC 780
YASIRAGRTLTPAGDLQETFSGMDQVRLMKRIAEMTDIKPILRKLPRIKKHLLNGDNMRC
Sbjct: 721 YASIRAGRTLTPAGDLQETFSGMDQVRLMKRIAEMTDIKPILRKLPRIKKHLLNGDNMRC 780
Query: 781 SVNATPQQMPQTEKAVEDFLRSIGRSKKERRPVRPHTVEKPVPSSSGGDAHVPHGSQVIR 840
SVNATPQQMPQTEKAVEDFLRSIGRSKKERRPVRPHTVEKPVPSSSGGDAHVPHGSQVIR
Sbjct: 781 SVNATPQQMPQTEKAVEDFLRSIGRSKKERRPVRPHTVEKPVPSSSGGDAHVPHGSQVIR 840
Query: 841 KLVMEPTFKPWQMKTHFLMPFPVNYVGECIRTVPYTDPDHASLKILARLMTAKFLHTEIR 900
KLVMEPTFKPWQMKTHFLMPFPVNYVGECIRTVPYTDPDHASLKILARLMTAKFLHTEIR
Sbjct: 841 KLVMEPTFKPWQMKTHFLMPFPVNYVGECIRTVPYTDPDHASLKILARLMTAKFLHTEIR 900
Query: 901 EKGGAYGGGAKLSHNGIFTLYSYRDPNTIETLQSFGKAVDWAKSGKFTQQDIDEAKLSVF 960
EKGGAYGGGAKLSHNGIFTLYSYRDPNTIETLQSFGKAVDWAKSGKFTQQDIDEAKLSVF
Sbjct: 901 EKGGAYGGGAKLSHNGIFTLYSYRDPNTIETLQSFGKAVDWAKSGKFTQQDIDEAKLSVF 960
Query: 961 STVDAPVAPSDKGMDHFLYGLSDEMKQAHREQLFAVSHDKLLAVSDRYLGTGKSTHGLAI 1020
STVDAPVAPSDKGMDHFLYGLSDEMKQAHREQLFAVSHDKLLAVSDRYLGTGKSTHGLAI
Sbjct: 961 STVDAPVAPSDKGMDHFLYGLSDEMKQAHREQLFAVSHDKLLAVSDRYLGTGKSTHGLAI 1020
Query: 1021 LGPENPKIAKDPSWIIQ 1037
LGPENPKIAKDPSWIIQ
Sbjct: 1021 LGPENPKIAKDPSWIIQ 1037
>gi|155969707 insulin-degrading enzyme [Homo sapiens]
Length = 1019
Score = 37.7 bits (86), Expect = 0.057
Identities = 22/76 (28%), Positives = 39/76 (51%), Gaps = 4/76 (5%)
Query: 96 PMDSTGVPHILEHTVLCGSQKYPCRDPFFKMLNRSLSTFMNAFTASDYTLYPFSTQNPKD 155
P + G+ H EH + G++KYP + + + L+ + NAFT+ ++T Y F + +
Sbjct: 100 PPNIAGLSHFCEHMLFLGTKKYPKENEYSQFLSEHAGS-SNAFTSGEHTNYYFDVSH-EH 157
Query: 156 FQNLLSVYLDATFFPC 171
+ L + A FF C
Sbjct: 158 LEGALDRF--AQFFLC 171
>gi|56119110 family with sequence similarity 13, member A1 isoform a
[Homo sapiens]
Length = 1023
Score = 37.7 bits (86), Expect = 0.057
Identities = 28/93 (30%), Positives = 49/93 (52%), Gaps = 6/93 (6%)
Query: 463 ELLKLGNQLAKFRQCLQENP-KFLQEKVKQYFKNNQHKLTLSMRPD-DKYHEKQAQVEAT 520
E+LK N LAKFR+ L+E+ K +E + + + L S +K EK+ ++
Sbjct: 704 EVLKWTNDLAKFRRQLKESKLKISEEDLTPRMRQRSNTLPKSFGSQLEKEDEKKQELVDK 763
Query: 521 KLKQKVEALSPGDRQQIYEKGLELRSQQSKPQD 553
+K VEA ++++ EK R++ S+P+D
Sbjct: 764 AIKPSVEATLESIQRKLQEK----RAESSRPED 792
>gi|62865869 family with sequence similarity 13, member A1 isoform b
[Homo sapiens]
Length = 697
Score = 37.7 bits (86), Expect = 0.057
Identities = 28/93 (30%), Positives = 49/93 (52%), Gaps = 6/93 (6%)
Query: 463 ELLKLGNQLAKFRQCLQENP-KFLQEKVKQYFKNNQHKLTLSMRPD-DKYHEKQAQVEAT 520
E+LK N LAKFR+ L+E+ K +E + + + L S +K EK+ ++
Sbjct: 378 EVLKWTNDLAKFRRQLKESKLKISEEDLTPRMRQRSNTLPKSFGSQLEKEDEKKQELVDK 437
Query: 521 KLKQKVEALSPGDRQQIYEKGLELRSQQSKPQD 553
+K VEA ++++ EK R++ S+P+D
Sbjct: 438 AIKPSVEATLESIQRKLQEK----RAESSRPED 466
>gi|156071452 nardilysin isoform b [Homo sapiens]
Length = 1151
Score = 36.2 bits (82), Expect = 0.16
Identities = 27/74 (36%), Positives = 36/74 (48%), Gaps = 4/74 (5%)
Query: 96 PMDSTGVPHILEHTVLCGSQKYPCRDPFFKMLNRSLSTFMNAFTASDYTLYPFSTQNPKD 155
P D G+ H LEH V GS KYP + F L + + NA T + T++ F Q K
Sbjct: 225 PDDLPGLAHFLEHMVFMGSLKYPDENGFDAFLKKHGGS-DNASTDCERTVFQFDVQR-KY 282
Query: 156 FQNLLSVYLDATFF 169
F+ L + A FF
Sbjct: 283 FKEALDRW--AQFF 294
>gi|156071450 nardilysin isoform a [Homo sapiens]
Length = 1219
Score = 36.2 bits (82), Expect = 0.16
Identities = 27/74 (36%), Positives = 36/74 (48%), Gaps = 4/74 (5%)
Query: 96 PMDSTGVPHILEHTVLCGSQKYPCRDPFFKMLNRSLSTFMNAFTASDYTLYPFSTQNPKD 155
P D G+ H LEH V GS KYP + F L + + NA T + T++ F Q K
Sbjct: 293 PDDLPGLAHFLEHMVFMGSLKYPDENGFDAFLKKHGGS-DNASTDCERTVFQFDVQR-KY 350
Query: 156 FQNLLSVYLDATFF 169
F+ L + A FF
Sbjct: 351 FKEALDRW--AQFF 362
>gi|83367077 mucin 16 [Homo sapiens]
Length = 14507
Score = 35.4 bits (80), Expect = 0.28
Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 9/80 (11%)
Query: 280 IHEEALSKFQKIEPSTV---VPAQTPWDKPREFQITCGPDSFATDPSKQTTISVSFLLPD 336
IH F +++ +T+ +P W P T P SF + P+ T +S LP
Sbjct: 5002 IHSAMTHGFSQLDVTTLMSRIPQDVSWTSPPSVDKTSSPSSFLSSPAMTTPSLISSTLP- 5060
Query: 337 ITDTFEAFTLSLLSSLLTSG 356
E S ++SLLTSG
Sbjct: 5061 -----EDKLSSPMTSLLTSG 5075
>gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens]
Length = 1233
Score = 35.0 bits (79), Expect = 0.37
Identities = 40/195 (20%), Positives = 83/195 (42%), Gaps = 40/195 (20%)
Query: 398 EKDIETVRSLIDRTIDEVVE-----------KGFEDDRIEAL--LHKIEIQMKHQSTSFG 444
E++++ ++ +++ DEV E + FE+++++ + K ++ ++Q T G
Sbjct: 759 EREMKDLKEKMNQVEDEVFEEFCREIGVRNIREFEEEKVKRQNEIAKKRLEFENQKTRLG 818
Query: 445 LMLTSYIASCWNHDGDPVELL-----KLGNQLAKFRQCLQENPKFLQEKVKQYFKNNQHK 499
+ L + + D D V + K N++ K ++ Q + K + E + Q
Sbjct: 819 IQL-DFEKNQLKEDQDKVHMWEQTVKKDENEIEKLKKEEQRHMKIIDETMAQLQDLKNQH 877
Query: 500 LTLSMRPDDKYHEKQ--------AQVEATKLKQKVEALSPGDRQQIYEKGLELRSQQSKP 551
L +DK HE + A E T L+++V A +E + +Q +
Sbjct: 878 LAKKSEVNDKNHEMEEIRKKLGGANKEMTHLQKEVTA-------------IETKLEQKRS 924
Query: 552 QDASCLPALKVSDIE 566
+ L A K+ DI+
Sbjct: 925 DRHNLLQACKMQDIK 939
Score = 30.4 bits (67), Expect = 9.0
Identities = 35/168 (20%), Positives = 70/168 (41%), Gaps = 19/168 (11%)
Query: 399 KDIETVRSLIDRTIDEVVEKGFEDDRIEALLHKIEIQMKHQSTSFGLMLTSYIASCWN-- 456
K+IE + +D+ DE+ EK E ++ +IE ++K + + YI + N
Sbjct: 247 KEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKENTS 306
Query: 457 HDGDPVELLKLG---------------NQLAKFRQCLQENPKFLQEKVKQYFKNNQHKLT 501
H +E K ++L K +++ + +E++++ ++ LT
Sbjct: 307 HKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEERMEEESQSQGRDLT 366
Query: 502 LSMRPDDKYH--EKQAQVEATKLKQKVEALSPGDRQQIYEKGLELRSQ 547
L KYH +++A A L Q++E + + LE R +
Sbjct: 367 LEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKK 414
>gi|239756691 PREDICTED: hypothetical protein [Homo sapiens]
Length = 319
Score = 32.7 bits (73), Expect = 1.8
Identities = 22/87 (25%), Positives = 37/87 (42%), Gaps = 15/87 (17%)
Query: 789 MPQTEKAVEDFLRSIGRSKKERR-------PVRPHTVEKPVPSSSGGDAHVPHGSQVIRK 841
MP K + LR+ RR P +PH +P+P + A GS+V+++
Sbjct: 1 MPTQGKLKKSLLRACVHGPPSRRQMRDQHPPHKPHPAPQPLPHQARDLAGEQEGSRVLQQ 60
Query: 842 LVMEPTF--------KPWQMKTHFLMP 860
L++ P F PW+ ++ P
Sbjct: 61 LLLVPNFILAGLRETNPWRRESREAEP 87
>gi|239751188 PREDICTED: hypothetical protein XP_002347742 [Homo
sapiens]
Length = 319
Score = 32.7 bits (73), Expect = 1.8
Identities = 22/87 (25%), Positives = 37/87 (42%), Gaps = 15/87 (17%)
Query: 789 MPQTEKAVEDFLRSIGRSKKERR-------PVRPHTVEKPVPSSSGGDAHVPHGSQVIRK 841
MP K + LR+ RR P +PH +P+P + A GS+V+++
Sbjct: 1 MPTQGKLKKSLLRACVHGPPSRRQMRDQHPPHKPHPAPQPLPHQARDLAGEQEGSRVLQQ 60
Query: 842 LVMEPTF--------KPWQMKTHFLMP 860
L++ P F PW+ ++ P
Sbjct: 61 LLLVPNFILAGLRETNPWRRESREAEP 87
>gi|239745676 PREDICTED: hypothetical protein XP_002343540 [Homo
sapiens]
Length = 319
Score = 32.7 bits (73), Expect = 1.8
Identities = 22/87 (25%), Positives = 37/87 (42%), Gaps = 15/87 (17%)
Query: 789 MPQTEKAVEDFLRSIGRSKKERR-------PVRPHTVEKPVPSSSGGDAHVPHGSQVIRK 841
MP K + LR+ RR P +PH +P+P + A GS+V+++
Sbjct: 1 MPTQGKLKKSLLRACVHGPPSRRQMRDQHPPHKPHPAPQPLPHQARDLAGEQEGSRVLQQ 60
Query: 842 LVMEPTF--------KPWQMKTHFLMP 860
L++ P F PW+ ++ P
Sbjct: 61 LLLVPNFILAGLRETNPWRRESREAEP 87
>gi|145580621 B and T lymphocyte associated isoform 1 [Homo sapiens]
Length = 289
Score = 32.7 bits (73), Expect = 1.8
Identities = 36/124 (29%), Positives = 54/124 (43%), Gaps = 16/124 (12%)
Query: 615 VPLFCSVLTKLGCGLLDYREQAQQIELK-TGGMSAS---PHVLPDDSHMDTYEQG-VLFS 669
+PL + L C L R Q +Q EL T G + H+ + + T + VL S
Sbjct: 164 LPLLITTCFCLFCCLR--RHQGKQNELSDTAGREINLVDAHLKSEQTEASTRQNSQVLLS 221
Query: 670 SLCLDRNLPDM---MQLWSEIFNNPCFEEEEHFKVLVKMT------AQELANGIPDSGHL 720
+ N PD+ MQ SE+++NPC EE + V + LA + ++
Sbjct: 222 ETGIYDNDPDLCFRMQEGSEVYSNPCLEENKPGIVYASLNHSVIGPNSRLARNVKEAPTE 281
Query: 721 YASI 724
YASI
Sbjct: 282 YASI 285
>gi|114155142 nuclear pore complex-associated protein TPR [Homo
sapiens]
Length = 2363
Score = 32.3 bits (72), Expect = 2.4
Identities = 19/73 (26%), Positives = 37/73 (50%), Gaps = 3/73 (4%)
Query: 460 DPVELLKLGNQLAKFRQCLQENPKFLQEKVKQYFKNNQHKLTLSMRPDDKYHEK---QAQ 516
D + L + +L++ LQ K L+E VK++ NQH ++ PD + + K + +
Sbjct: 1303 DILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQHLVSQQKDPDTEEYRKLLSEKE 1362
Query: 517 VEATKLKQKVEAL 529
V +++Q E +
Sbjct: 1363 VHTKRIQQLTEEI 1375
>gi|40316946 ADP-ribosylhydrolase like 1 isoform 2 [Homo sapiens]
Length = 272
Score = 32.3 bits (72), Expect = 2.4
Identities = 21/68 (30%), Positives = 31/68 (45%), Gaps = 7/68 (10%)
Query: 868 ECIRTVPYTDPDHASLKILARLMTAKFL---HTEIREKGGAYGGGAKLSHNGIFTLYSYR 924
E + +P PD A+++ A+L +L HT EKG +G K G+ Y
Sbjct: 7 EIVEKLPERRPDPATIEGCAQLKPNNYLLAWHTPFNEKGSGFGAATKAMCIGL----RYW 62
Query: 925 DPNTIETL 932
P +ETL
Sbjct: 63 KPERLETL 70
>gi|21702735 ADP-ribosylhydrolase like 1 isoform 1 [Homo sapiens]
Length = 354
Score = 32.3 bits (72), Expect = 2.4
Identities = 21/68 (30%), Positives = 31/68 (45%), Gaps = 7/68 (10%)
Query: 868 ECIRTVPYTDPDHASLKILARLMTAKFL---HTEIREKGGAYGGGAKLSHNGIFTLYSYR 924
E + +P PD A+++ A+L +L HT EKG +G K G+ Y
Sbjct: 89 EIVEKLPERRPDPATIEGCAQLKPNNYLLAWHTPFNEKGSGFGAATKAMCIGL----RYW 144
Query: 925 DPNTIETL 932
P +ETL
Sbjct: 145 KPERLETL 152
>gi|242332527 hypothetical protein LOC65250 [Homo sapiens]
Length = 3197
Score = 31.6 bits (70), Expect = 4.1
Identities = 19/52 (36%), Positives = 29/52 (55%), Gaps = 3/52 (5%)
Query: 801 RSIGRSKKERRPVRPHTVEKPVPS---SSGGDAHVPHGSQVIRKLVMEPTFK 849
+S+G + +E R PH E +PS S+G +VPHGS + +L +P K
Sbjct: 2122 QSMGENAREPRKNSPHCHEGTIPSGQNSTGNVQNVPHGSIPLCQLNGQPRKK 2173
>gi|58530876 melanoma antigen family C, 1 [Homo sapiens]
Length = 1142
Score = 31.6 bits (70), Expect = 4.1
Identities = 44/188 (23%), Positives = 71/188 (37%), Gaps = 28/188 (14%)
Query: 272 PLEQHLKQIHEEAL-SKFQKIEPSTVVPAQTPWDKPREFQITCGPDSFATDPSKQTTISV 330
PL++ + L S Q S P + P P + ++ P S ++ S+ + +S
Sbjct: 774 PLQRPVSSFFSYTLASLLQSSHESPQSPPEGPAQSPLQSPVSSFPSSTSSSLSQSSPVS- 832
Query: 331 SFLLPDITDTFEAFTLSLLSSLLTSGPNSPFYKALIESGLGTDFSPDVGYNGYTREAYFS 390
+F S SSL S P SP +I T SP + + Y S
Sbjct: 833 ------------SFPSSTSSSLSKSSPESPLQSPVISFSSSTSLSPFSEESSSPVDEYTS 880
Query: 391 VGLQGIAEKDIETVRSLIDR------TIDEVVEKGFEDDRIEALLHKIEIQMKHQSTSFG 444
+ + SLI+ T+DE V D+ LL K +++ Q +
Sbjct: 881 SSDTLLESDSLTDSESLIESEPLFTYTLDEKV-----DELARFLLLKYQVK---QPITKA 932
Query: 445 LMLTSYIA 452
MLT+ I+
Sbjct: 933 EMLTNVIS 940
>gi|102468717 mediator complex subunit 13 [Homo sapiens]
Length = 2174
Score = 31.6 bits (70), Expect = 4.1
Identities = 26/89 (29%), Positives = 42/89 (47%), Gaps = 6/89 (6%)
Query: 305 KPREFQITCGPDSFATDPSKQTTISVSFLLPDITDTFEAFTLSLLSSLLTSGPNSPFYKA 364
KP QI G FA + + LP+ +++T+ L LL+SGP+ PF
Sbjct: 904 KPENCQILVGCSMFAPLKTLPSQYLPPIKLPEECIYRQSWTVGKLE-LLSSGPSMPF--- 959
Query: 365 LIESGLGTDFSPDVGYNGYTREAYFSVGL 393
I+ G G++ + G YT + + S G+
Sbjct: 960 -IKEGDGSNMDQEYG-TAYTPQTHTSFGM 986
>gi|95147555 microtubule-associated protein 1A [Homo sapiens]
Length = 2803
Score = 31.2 bits (69), Expect = 5.3
Identities = 74/346 (21%), Positives = 133/346 (38%), Gaps = 39/346 (11%)
Query: 243 PELTWEQLKQFHATHYHPSNARFFTYGNFPLEQHLKQIHEEALSKFQ-------KIEPST 295
PE++ E + + PS L+ KQ+ E+L Q K E
Sbjct: 1187 PEVSPEDTQSLSLSEESPSKET-------SLDVSSKQLSPESLGTLQFGELNLGKEEMGH 1239
Query: 296 VVPAQ------TPWDKPREFQITCGPDSFATDPSKQTTISVSFLLPDITD-TFEAFTLSL 348
++ A+ P P T P + T T DITD + + + +
Sbjct: 1240 LMQAEDTSHHTAPMSVPEPHAATASPPTDGTTRYSAQT--------DITDDSLDRKSPAS 1291
Query: 349 LSSLLTSGPNSPFYKALIESGLGTDFSPDVGYNGYTREAYFSVGLQGIAEKDIETVRSLI 408
S T N + I S +PD ++ + E+ L+ IA K + V L
Sbjct: 1292 SFSHSTPSGNGKYLPGAITSPDEHILTPDSSFSK-SPESLPGPALEDIAIKWEDKVPGLK 1350
Query: 409 DRTIDEVVEKGFEDDRIE----ALLHKIEIQMKHQSTSFGLMLTSYIASCWNHDGDPVEL 464
DRT ++ E +D+ ++ L HK ++ K + + ++ + D L
Sbjct: 1351 DRTSEQKKEPEPKDEVLQQKDKTLEHKEVVEPK-DTAIYQKDEALHVKNEAVKQQDKA-L 1408
Query: 465 LKLGNQLAKFRQCLQENPKFLQEKVKQYFKNNQHKLTLSMRPDDKYHEKQAQVEATKLKQ 524
+ G L + L++ K L+ K K + ++ P++K +K + + T L+Q
Sbjct: 1409 EQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKIPEEK--DKALEQKDTALEQ 1466
Query: 525 KVEALSPGDRQQIYEKGLELRSQQSKPQDASCLPALKVSDIEPTIP 570
K +AL P D+ + +K L ++ P++ KV +E P
Sbjct: 1467 KDKALEPKDK-DLEQKDRVLEQKEKIPEEKDKALDQKVRSVEHKAP 1511
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 31.2 bits (69), Expect = 5.3
Identities = 26/87 (29%), Positives = 45/87 (51%), Gaps = 12/87 (13%)
Query: 469 NQLAKFRQCLQENPKFL-------QEKVKQYFK-NNQHKLTLSMRPDDKYHEKQAQVEAT 520
N+L+K R+ L+E L +EK K K N+H+ +S E++++ E
Sbjct: 995 NKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELE 1054
Query: 521 KLKQKVEALSPGDRQQIYEKGLELRSQ 547
KLK+K+E GD +E+ +L++Q
Sbjct: 1055 KLKRKLE----GDASDFHEQIADLQAQ 1077
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 31.2 bits (69), Expect = 5.3
Identities = 26/87 (29%), Positives = 45/87 (51%), Gaps = 12/87 (13%)
Query: 469 NQLAKFRQCLQENPKFL-------QEKVKQYFK-NNQHKLTLSMRPDDKYHEKQAQVEAT 520
N+L+K R+ L+E L +EK K K N+H+ +S E++++ E
Sbjct: 1002 NKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELE 1061
Query: 521 KLKQKVEALSPGDRQQIYEKGLELRSQ 547
KLK+K+E GD +E+ +L++Q
Sbjct: 1062 KLKRKLE----GDASDFHEQIADLQAQ 1084
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 31.2 bits (69), Expect = 5.3
Identities = 26/87 (29%), Positives = 45/87 (51%), Gaps = 12/87 (13%)
Query: 469 NQLAKFRQCLQENPKFL-------QEKVKQYFK-NNQHKLTLSMRPDDKYHEKQAQVEAT 520
N+L+K R+ L+E L +EK K K N+H+ +S E++++ E
Sbjct: 1002 NKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELE 1061
Query: 521 KLKQKVEALSPGDRQQIYEKGLELRSQ 547
KLK+K+E GD +E+ +L++Q
Sbjct: 1062 KLKRKLE----GDASDFHEQIADLQAQ 1084
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 31.2 bits (69), Expect = 5.3
Identities = 26/87 (29%), Positives = 45/87 (51%), Gaps = 12/87 (13%)
Query: 469 NQLAKFRQCLQENPKFL-------QEKVKQYFK-NNQHKLTLSMRPDDKYHEKQAQVEAT 520
N+L+K R+ L+E L +EK K K N+H+ +S E++++ E
Sbjct: 995 NKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELE 1054
Query: 521 KLKQKVEALSPGDRQQIYEKGLELRSQ 547
KLK+K+E GD +E+ +L++Q
Sbjct: 1055 KLKRKLE----GDASDFHEQIADLQAQ 1077
>gi|94680976 coiled-coil domain containing 112 isoform 1 [Homo
sapiens]
Length = 529
Score = 31.2 bits (69), Expect = 5.3
Identities = 33/128 (25%), Positives = 58/128 (45%), Gaps = 14/128 (10%)
Query: 433 EIQMKHQST-----SFGLMLTSYIASCWNHDGDPVELLKLGNQLAKFRQCLQENPKFLQE 487
E + KHQ L+L SY + E L+L ++ + + E K +
Sbjct: 382 EKEKKHQKERQRQFKLKLLLESYT----QQKKEQEEFLRLEKEIREKAE-KAEKRKNAAD 436
Query: 488 KVKQYFKNNQHKLTLSM--RPDDKYHEKQAQVEATKLKQKVEALSPGDRQQIYE--KGLE 543
++ ++ + + HKL L + R + + Q Q KLK+KVE D ++Y+ KG E
Sbjct: 437 EISRFQERDLHKLELKILDRQAKEDEKSQKQRRLAKLKEKVENNVSRDPSRLYKPTKGWE 496
Query: 544 LRSQQSKP 551
R+++ P
Sbjct: 497 ERTKKIGP 504
>gi|145580595 coiled-coil domain containing 112 isoform 2 [Homo
sapiens]
Length = 446
Score = 31.2 bits (69), Expect = 5.3
Identities = 33/128 (25%), Positives = 58/128 (45%), Gaps = 14/128 (10%)
Query: 433 EIQMKHQST-----SFGLMLTSYIASCWNHDGDPVELLKLGNQLAKFRQCLQENPKFLQE 487
E + KHQ L+L SY + E L+L ++ + + E K +
Sbjct: 299 EKEKKHQKERQRQFKLKLLLESYT----QQKKEQEEFLRLEKEIREKAE-KAEKRKNAAD 353
Query: 488 KVKQYFKNNQHKLTLSM--RPDDKYHEKQAQVEATKLKQKVEALSPGDRQQIYE--KGLE 543
++ ++ + + HKL L + R + + Q Q KLK+KVE D ++Y+ KG E
Sbjct: 354 EISRFQERDLHKLELKILDRQAKEDEKSQKQRRLAKLKEKVENNVSRDPSRLYKPTKGWE 413
Query: 544 LRSQQSKP 551
R+++ P
Sbjct: 414 ERTKKIGP 421
>gi|226437579 NAC alpha domain containing [Homo sapiens]
Length = 1562
Score = 30.8 bits (68), Expect = 6.9
Identities = 16/49 (32%), Positives = 27/49 (55%), Gaps = 3/49 (6%)
Query: 260 PSNARFFTYGNFPLEQHLKQIHEEALSKFQ-KIEPSTVVPAQTPWDKPR 307
P++ + +G +E +Q+H+ A KF+ EPS +VP P +PR
Sbjct: 1456 PASDTYVVFGEAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAP--RPR 1502
>gi|239754540 PREDICTED: NAC alpha domain containing [Homo sapiens]
Length = 1522
Score = 30.8 bits (68), Expect = 6.9
Identities = 16/49 (32%), Positives = 27/49 (55%), Gaps = 3/49 (6%)
Query: 260 PSNARFFTYGNFPLEQHLKQIHEEALSKFQ-KIEPSTVVPAQTPWDKPR 307
P++ + +G +E +Q+H+ A KF+ EPS +VP P +PR
Sbjct: 1416 PASDTYVVFGEAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAP--RPR 1462
>gi|239749105 PREDICTED: NAC alpha domain containing [Homo sapiens]
Length = 1522
Score = 30.8 bits (68), Expect = 6.9
Identities = 16/49 (32%), Positives = 27/49 (55%), Gaps = 3/49 (6%)
Query: 260 PSNARFFTYGNFPLEQHLKQIHEEALSKFQ-KIEPSTVVPAQTPWDKPR 307
P++ + +G +E +Q+H+ A KF+ EPS +VP P +PR
Sbjct: 1416 PASDTYVVFGEAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAP--RPR 1462
>gi|239743134 PREDICTED: NAC alpha domain containing [Homo sapiens]
Length = 1562
Score = 30.8 bits (68), Expect = 6.9
Identities = 16/49 (32%), Positives = 27/49 (55%), Gaps = 3/49 (6%)
Query: 260 PSNARFFTYGNFPLEQHLKQIHEEALSKFQ-KIEPSTVVPAQTPWDKPR 307
P++ + +G +E +Q+H+ A KF+ EPS +VP P +PR
Sbjct: 1456 PASDTYVVFGEAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAP--RPR 1502
>gi|239508792 PREDICTED: NAC alpha domain containing [Homo sapiens]
Length = 1522
Score = 30.8 bits (68), Expect = 6.9
Identities = 16/49 (32%), Positives = 27/49 (55%), Gaps = 3/49 (6%)
Query: 260 PSNARFFTYGNFPLEQHLKQIHEEALSKFQ-KIEPSTVVPAQTPWDKPR 307
P++ + +G +E +Q+H+ A KF+ EPS +VP P +PR
Sbjct: 1416 PASDTYVVFGEAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAP--RPR 1462
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,797,100
Number of Sequences: 37866
Number of extensions: 1957323
Number of successful extensions: 5156
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 30
Number of HSP's that attempted gapping in prelim test: 5140
Number of HSP's gapped (non-prelim): 53
length of query: 1037
length of database: 18,247,518
effective HSP length: 112
effective length of query: 925
effective length of database: 14,006,526
effective search space: 12956036550
effective search space used: 12956036550
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.