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Search of human proteins with 41281905
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|41281905 fermitin family homolog 3 long form [Homo sapiens]
(667 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|41281905 fermitin family homolog 3 long form [Homo sapiens] 1353 0.0
gi|28626504 fermitin family homolog 3 short form [Homo sapiens] 1340 0.0
gi|29789006 fermitin family homolog 2 isoform 1 [Homo sapiens] 733 0.0
gi|116686114 kindlin-1 [Homo sapiens] 728 0.0
gi|201861813 fermitin family homolog 2 isoform 2 [Homo sapiens] 726 0.0
gi|201861823 fermitin family homolog 2 isoform 3 [Homo sapiens] 664 0.0
gi|223029410 talin 1 [Homo sapiens] 64 4e-10
gi|156938343 talin 2 [Homo sapiens] 59 1e-08
gi|4505531 oxysterol binding protein [Homo sapiens] 37 0.059
gi|14165452 alpha 3 type IV collagen binding protein isoform 2 [... 37 0.077
gi|194294543 alpha 3 type IV collagen binding protein isoform 3 ... 37 0.077
gi|5031717 alpha 3 type IV collagen binding protein isoform 1 [H... 37 0.077
gi|54792084 pleckstrin homology domain containing, family A (pho... 35 0.22
gi|5031633 FERM, RhoGEF, and pleckstrin domain protein 1 isoform... 35 0.29
gi|56118221 amyloid beta (A4) precursor protein-binding, family ... 34 0.38
gi|22027480 pogo transposable element with KRAB domain [Homo sap... 34 0.38
gi|13540513 oxysterol binding protein 2 isoform a [Homo sapiens] 33 0.65
gi|4502435 BMX non-receptor tyrosine kinase [Homo sapiens] 33 0.85
gi|42544182 BMX non-receptor tyrosine kinase [Homo sapiens] 33 0.85
gi|239745081 PREDICTED: similar to Golgin subfamily A member 8-l... 33 0.85
gi|197382472 actin filament associated protein 1 isoform a [Homo... 32 1.9
gi|40807504 actin filament associated protein 1 [Homo sapiens] 32 1.9
gi|50355978 T-cell leukemia homeobox 3 [Homo sapiens] 32 2.5
gi|154354979 myosin X [Homo sapiens] 31 4.2
gi|51243032 oxysterol-binding protein-like protein 8 isoform b [... 31 4.2
gi|18079218 oxysterol-binding protein-like protein 8 isoform a [... 31 4.2
gi|157266334 tubby like protein 1 [Homo sapiens] 31 4.2
gi|110346438 FERM and PDZ domain containing 2 isoform 1 [Homo sa... 31 4.2
gi|110346436 FERM and PDZ domain containing 2 isoform 3 [Homo sa... 31 4.2
gi|113425145 PREDICTED: similar to Golgin subfamily A member 8-l... 30 5.5
>gi|41281905 fermitin family homolog 3 long form [Homo sapiens]
Length = 667
Score = 1353 bits (3503), Expect = 0.0
Identities = 667/667 (100%), Positives = 667/667 (100%)
Query: 1 MAGMKTASGDYIDSSWELRVFVGEEDPEAESVTLRVTGESHIGGVLLKIVEQINRKQDWS 60
MAGMKTASGDYIDSSWELRVFVGEEDPEAESVTLRVTGESHIGGVLLKIVEQINRKQDWS
Sbjct: 1 MAGMKTASGDYIDSSWELRVFVGEEDPEAESVTLRVTGESHIGGVLLKIVEQINRKQDWS 60
Query: 61 DHAIWWEQKRQWLLQTHWTLDKYGILADARLFFGPQHRPVILRLPNRRALRLRASFSQPL 120
DHAIWWEQKRQWLLQTHWTLDKYGILADARLFFGPQHRPVILRLPNRRALRLRASFSQPL
Sbjct: 61 DHAIWWEQKRQWLLQTHWTLDKYGILADARLFFGPQHRPVILRLPNRRALRLRASFSQPL 120
Query: 121 FQAVAAICRLLSIRHPEELSLLRAPEKKEKKKKEKEPEEELYDLSKVVLAGGVAPALFRG 180
FQAVAAICRLLSIRHPEELSLLRAPEKKEKKKKEKEPEEELYDLSKVVLAGGVAPALFRG
Sbjct: 121 FQAVAAICRLLSIRHPEELSLLRAPEKKEKKKKEKEPEEELYDLSKVVLAGGVAPALFRG 180
Query: 181 MPAHFSDSAQTEACYHMLSRPQPPPDPLLLQRLPRPSSLSDKTQLHSRWLDSSRCLMQQG 240
MPAHFSDSAQTEACYHMLSRPQPPPDPLLLQRLPRPSSLSDKTQLHSRWLDSSRCLMQQG
Sbjct: 181 MPAHFSDSAQTEACYHMLSRPQPPPDPLLLQRLPRPSSLSDKTQLHSRWLDSSRCLMQQG 240
Query: 241 IKAGDALWLRFKYYSFFDLDPKTDPVRLTQLYEQARWDLLLEEIDCTEEEMMVFAALQYH 300
IKAGDALWLRFKYYSFFDLDPKTDPVRLTQLYEQARWDLLLEEIDCTEEEMMVFAALQYH
Sbjct: 241 IKAGDALWLRFKYYSFFDLDPKTDPVRLTQLYEQARWDLLLEEIDCTEEEMMVFAALQYH 300
Query: 301 INKLSQSGEVGEPAGTDPGLDDLDVALSNLEVKLEGSAPTDVLDSLTTIPELKDHLRIFR 360
INKLSQSGEVGEPAGTDPGLDDLDVALSNLEVKLEGSAPTDVLDSLTTIPELKDHLRIFR
Sbjct: 301 INKLSQSGEVGEPAGTDPGLDDLDVALSNLEVKLEGSAPTDVLDSLTTIPELKDHLRIFR 360
Query: 361 IPRRPRKLTLKGYRQHWVVFKETTLSYYKSQDEAPGDPIQQLNLKGCEVVPDVNVSGQKF 420
IPRRPRKLTLKGYRQHWVVFKETTLSYYKSQDEAPGDPIQQLNLKGCEVVPDVNVSGQKF
Sbjct: 361 IPRRPRKLTLKGYRQHWVVFKETTLSYYKSQDEAPGDPIQQLNLKGCEVVPDVNVSGQKF 420
Query: 421 CIKLLVPSPEGMSEIYLRCQDEQQYARWMAGCRLASKGRTMADSSYTSEVQAILAFLSLQ 480
CIKLLVPSPEGMSEIYLRCQDEQQYARWMAGCRLASKGRTMADSSYTSEVQAILAFLSLQ
Sbjct: 421 CIKLLVPSPEGMSEIYLRCQDEQQYARWMAGCRLASKGRTMADSSYTSEVQAILAFLSLQ 480
Query: 481 RTGSGGPGNHPHGPDASAEGLNPYGLVAPRFQRKFKAKQLTPRILEAHQNVAQLSLAEAQ 540
RTGSGGPGNHPHGPDASAEGLNPYGLVAPRFQRKFKAKQLTPRILEAHQNVAQLSLAEAQ
Sbjct: 481 RTGSGGPGNHPHGPDASAEGLNPYGLVAPRFQRKFKAKQLTPRILEAHQNVAQLSLAEAQ 540
Query: 541 LRFIQAWQSLPDFGISYVMVRFKGSRKDEILGIANNRLIRIDLAVGDVVKTWRFSNMRQW 600
LRFIQAWQSLPDFGISYVMVRFKGSRKDEILGIANNRLIRIDLAVGDVVKTWRFSNMRQW
Sbjct: 541 LRFIQAWQSLPDFGISYVMVRFKGSRKDEILGIANNRLIRIDLAVGDVVKTWRFSNMRQW 600
Query: 601 NVNWDIRQVAIEFDEHINVAFSCVSASCRIVHEYIGGYIFLSTRERARGEELDEDLFLQL 660
NVNWDIRQVAIEFDEHINVAFSCVSASCRIVHEYIGGYIFLSTRERARGEELDEDLFLQL
Sbjct: 601 NVNWDIRQVAIEFDEHINVAFSCVSASCRIVHEYIGGYIFLSTRERARGEELDEDLFLQL 660
Query: 661 TGGHEAF 667
TGGHEAF
Sbjct: 661 TGGHEAF 667
>gi|28626504 fermitin family homolog 3 short form [Homo sapiens]
Length = 663
Score = 1340 bits (3467), Expect = 0.0
Identities = 663/667 (99%), Positives = 663/667 (99%), Gaps = 4/667 (0%)
Query: 1 MAGMKTASGDYIDSSWELRVFVGEEDPEAESVTLRVTGESHIGGVLLKIVEQINRKQDWS 60
MAGMKTASGDYIDSSWELRVFVGEEDPEAESVTLRVTGESHIGGVLLKIVEQINRKQDWS
Sbjct: 1 MAGMKTASGDYIDSSWELRVFVGEEDPEAESVTLRVTGESHIGGVLLKIVEQINRKQDWS 60
Query: 61 DHAIWWEQKRQWLLQTHWTLDKYGILADARLFFGPQHRPVILRLPNRRALRLRASFSQPL 120
DHAIWWEQKRQWLLQTHWTLDKYGILADARLFFGPQHRPVILRLPNRRALRLRASFSQPL
Sbjct: 61 DHAIWWEQKRQWLLQTHWTLDKYGILADARLFFGPQHRPVILRLPNRRALRLRASFSQPL 120
Query: 121 FQAVAAICRLLSIRHPEELSLLRAPEKKEKKKKEKEPEEELYDLSKVVLAGGVAPALFRG 180
FQAVAAICRLLSIRHPEELSLLRAPEKKEKKKKEKEPEEELYDLSKVVLAGGVAPALFRG
Sbjct: 121 FQAVAAICRLLSIRHPEELSLLRAPEKKEKKKKEKEPEEELYDLSKVVLAGGVAPALFRG 180
Query: 181 MPAHFSDSAQTEACYHMLSRPQPPPDPLLLQRLPRPSSLSDKTQLHSRWLDSSRCLMQQG 240
MPAHFSDSAQTEACYHMLSRPQPPPDPLLLQRLPRPSSLSDKTQLHSRWLDSSRCLMQQG
Sbjct: 181 MPAHFSDSAQTEACYHMLSRPQPPPDPLLLQRLPRPSSLSDKTQLHSRWLDSSRCLMQQG 240
Query: 241 IKAGDALWLRFKYYSFFDLDPKTDPVRLTQLYEQARWDLLLEEIDCTEEEMMVFAALQYH 300
IKAGDALWLRFKYYSFFDLDPKTDPVRLTQLYEQARWDLLLEEIDCTEEEMMVFAALQYH
Sbjct: 241 IKAGDALWLRFKYYSFFDLDPKTDPVRLTQLYEQARWDLLLEEIDCTEEEMMVFAALQYH 300
Query: 301 INKLSQSGEVGEPAGTDPGLDDLDVALSNLEVKLEGSAPTDVLDSLTTIPELKDHLRIFR 360
INKLSQSGEVGEPAGTDPGLDDLDVALSNLEVKLEGSAPTDVLDSLTTIPELKDHLRIF
Sbjct: 301 INKLSQSGEVGEPAGTDPGLDDLDVALSNLEVKLEGSAPTDVLDSLTTIPELKDHLRIF- 359
Query: 361 IPRRPRKLTLKGYRQHWVVFKETTLSYYKSQDEAPGDPIQQLNLKGCEVVPDVNVSGQKF 420
RPRKLTLKGYRQHWVVFKETTLSYYKSQDEAPGDPIQQLNLKGCEVVPDVNVSGQKF
Sbjct: 360 ---RPRKLTLKGYRQHWVVFKETTLSYYKSQDEAPGDPIQQLNLKGCEVVPDVNVSGQKF 416
Query: 421 CIKLLVPSPEGMSEIYLRCQDEQQYARWMAGCRLASKGRTMADSSYTSEVQAILAFLSLQ 480
CIKLLVPSPEGMSEIYLRCQDEQQYARWMAGCRLASKGRTMADSSYTSEVQAILAFLSLQ
Sbjct: 417 CIKLLVPSPEGMSEIYLRCQDEQQYARWMAGCRLASKGRTMADSSYTSEVQAILAFLSLQ 476
Query: 481 RTGSGGPGNHPHGPDASAEGLNPYGLVAPRFQRKFKAKQLTPRILEAHQNVAQLSLAEAQ 540
RTGSGGPGNHPHGPDASAEGLNPYGLVAPRFQRKFKAKQLTPRILEAHQNVAQLSLAEAQ
Sbjct: 477 RTGSGGPGNHPHGPDASAEGLNPYGLVAPRFQRKFKAKQLTPRILEAHQNVAQLSLAEAQ 536
Query: 541 LRFIQAWQSLPDFGISYVMVRFKGSRKDEILGIANNRLIRIDLAVGDVVKTWRFSNMRQW 600
LRFIQAWQSLPDFGISYVMVRFKGSRKDEILGIANNRLIRIDLAVGDVVKTWRFSNMRQW
Sbjct: 537 LRFIQAWQSLPDFGISYVMVRFKGSRKDEILGIANNRLIRIDLAVGDVVKTWRFSNMRQW 596
Query: 601 NVNWDIRQVAIEFDEHINVAFSCVSASCRIVHEYIGGYIFLSTRERARGEELDEDLFLQL 660
NVNWDIRQVAIEFDEHINVAFSCVSASCRIVHEYIGGYIFLSTRERARGEELDEDLFLQL
Sbjct: 597 NVNWDIRQVAIEFDEHINVAFSCVSASCRIVHEYIGGYIFLSTRERARGEELDEDLFLQL 656
Query: 661 TGGHEAF 667
TGGHEAF
Sbjct: 657 TGGHEAF 663
>gi|29789006 fermitin family homolog 2 isoform 1 [Homo sapiens]
Length = 680
Score = 733 bits (1892), Expect = 0.0
Identities = 362/685 (52%), Positives = 496/685 (72%), Gaps = 35/685 (5%)
Query: 3 GMKTASGDYIDSSWELRVFVGEEDPEAESVTLRVTGESHIGGVLLKIVEQINRKQDWSDH 62
G++ G Y D +WEL V V + + + VTLRVTGE HIGGV+LK+VE+++ K+DWSDH
Sbjct: 5 GIRMPDGCYADGTWELSVHVTDLNRD---VTLRVTGEVHIGGVMLKLVEKLDVKKDWSDH 61
Query: 63 AIWWEQKRQWLLQTHWTLDKYGILADARLFFGPQHRPVILRLPNRRALRLRASFSQPLFQ 122
A+WWE+KR WLL+THWTLDKYGI ADA+L F PQH+ + L+LPN + ++++ +FS +F+
Sbjct: 62 ALWWEKKRTWLLKTHWTLDKYGIQADAKLQFTPQHKLLRLQLPNMKYVKVKVNFSDRVFK 121
Query: 123 AVAAICRLLSIRHPEELSLL---RAPEKKEKKKKEKEPEEELYDLSKVVLAGGV-----A 174
AV+ IC+ +IRHPEELSLL R P KK+KKK + + E+E +L ++ G +
Sbjct: 122 AVSDICKTFNIRHPEELSLLKKPRDPTKKKKKKLDDQSEDEALELEGPLITPGSGSIYSS 181
Query: 175 PALFR-----------GMP-----AHFSDSAQTEACYHMLSRPQPPPDPLLLQRLPRPSS 218
P L+ G P A F DSA +E +L+ QP P +L ++ +P +
Sbjct: 182 PGLYSKTMTPTYDAHDGSPLSPTSAWFGDSALSEGNPGILAVSQPITSPEILAKMFKPQA 241
Query: 219 LSDKTQLHSRWLDSSRCLMQQGIKAGDALWLRFKYYSFFDLDPKTDPVRLTQLYEQARWD 278
L DK +++ WLDSSR LM+Q +K +AL LRFKYYSFFDL+PK D +R+ QLYEQA+W
Sbjct: 242 LLDKAKINQGWLDSSRSLMEQDVKENEALLLRFKYYSFFDLNPKYDAIRINQLYEQAKWA 301
Query: 279 LLLEEIDCTEEEMMVFAALQYHINKLSQSGEVGEPAGTDPGLDDLDVALSNLEVKLEGSA 338
+LLEEI+CTEEEMM+FAALQYHINKLS +D +D++D ALS+LE+ LEG
Sbjct: 302 ILLEEIECTEEEMMMFAALQYHINKLSIMTSENHLNNSDKEVDEVDAALSDLEITLEGGK 361
Query: 339 PTDVLDSLTTIPELKDHLRIFRIPRRPRKLTLKGYRQHWVVFKETTLSYYKSQDEAPGDP 398
+ +L +T+IPEL D++++F+ P+KLTLKGY+Q+W FK+T++S YKS++E+ G P
Sbjct: 362 TSTILGDITSIPELADYIKVFK----PKKLTLKGYKQYWCTFKDTSISCYKSKEESSGTP 417
Query: 399 IQQLNLKGCEVVPDVNVSGQKFCIKLLVPSPEGMSEIYLRCQDEQQYARWMAGCRLASKG 458
Q+NL+GCEV PDVN+SGQKF IKLL+P EGM+EI+LRC +E+QYA WMA CRLASKG
Sbjct: 418 AHQMNLRGCEVTPDVNISGQKFNIKLLIPVAEGMNEIWLRCDNEKQYAHWMAACRLASKG 477
Query: 459 RTMADSSYTSEVQAILAFLSLQRTGSGGPGNHPHGPDASAEGLNPYGLVAPRFQRKFKAK 518
+TMADSSY EVQ IL+FL +Q + P+ + P LV+PR+ +K+K K
Sbjct: 478 KTMADSSYNLEVQNILSFLKMQHLNP----DPQLIPEQITTDITPECLVSPRYLKKYKNK 533
Query: 519 QLTPRILEAHQNVAQLSLAEAQLRFIQAWQSLPDFGISYVMVRFKGSRKDEILGIANNRL 578
Q+T RILEAHQNVAQ+SL EA++RFIQAWQSLP+FGI++ + RF+G +K+E++GIA NRL
Sbjct: 534 QITARILEAHQNVAQMSLIEAKMRFIQAWQSLPEFGITHFIARFQGGKKEELIGIAYNRL 593
Query: 579 IRIDLAVGDVVKTWRFSNMRQWNVNWDIRQVAIEFDEHINVAFSCVSASCRIVHEYIGGY 638
IR+D + GD +KTWRFSNM+QWNVNW+I+ V +EF + + ++F C C++VHE+IGGY
Sbjct: 594 IRMDASTGDAIKTWRFSNMKQWNVNWEIKMVTVEFADEVRLSFICTEVDCKVVHEFIGGY 653
Query: 639 IFLSTRERARGEELDEDLFLQLTGG 663
IFLSTR + + E LDE++F +LT G
Sbjct: 654 IFLSTRAKDQNESLDEEMFYKLTSG 678
>gi|116686114 kindlin-1 [Homo sapiens]
Length = 677
Score = 728 bits (1880), Expect = 0.0
Identities = 375/684 (54%), Positives = 495/684 (72%), Gaps = 34/684 (4%)
Query: 7 ASGDYIDSSWELRVFVGEEDPEAES-VTLRVTGESHIGGVLLKIVEQINRKQDWSDHAIW 65
+S D+ +SWEL V V + E + VTLRV+G+ H+GGV+LK+VEQIN QDWSD A+W
Sbjct: 3 SSTDFTFASWELVVRVDHPNEEQQKDVTLRVSGDLHVGGVMLKLVEQINISQDWSDFALW 62
Query: 66 WEQKRQWLLQTHWTLDKYGILADARLFFGPQHRPVILRLPNRRALRLRASFSQPLFQAVA 125
WEQK WLL+THWTLDKYG+ ADA+L F PQH+ + LRLPN + +RLR SFS +F+AV+
Sbjct: 63 WEQKHCWLLKTHWTLDKYGVQADAKLLFTPQHKMLRLRLPNLKMVRLRVSFSAVVFKAVS 122
Query: 126 AICRLLSIRHPEELSLLRAP-----EKKEKKKKEKEPE-EELYDLSKVVLAGG--VAPAL 177
IC++L+IR EELSLL+ +KK+K K KEP E++ +L A G V+P L
Sbjct: 123 DICKILNIRRSEELSLLKPSGDYFKKKKKKDKNNKEPIIEDILNLESSPTASGSSVSPGL 182
Query: 178 F-----------RGMPAH-----FSDSAQTEACYHMLSRPQPPPDPLLLQRLPRPSSLSD 221
+ G PA FSDS TE +L+ QPP P L + +P SL D
Sbjct: 183 YSKTMTPIYDPINGTPASSTMTWFSDSPLTEQNCSILAFSQPPQSPEALADMYQPRSLVD 242
Query: 222 KTQLHSRWLDSSRCLMQQGIKAGDALWLRFKYYSFFDLDPKTDPVRLTQLYEQARWDLLL 281
K +L++ WLDSSR LM+QGI+ + L LRFKYYSFFDL+PK D VR+ QLYEQARW +LL
Sbjct: 243 KAKLNAGWLDSSRSLMEQGIQEDEQLLLRFKYYSFFDLNPKYDAVRINQLYEQARWAILL 302
Query: 282 EEIDCTEEEMMVFAALQYHINKLSQSGEVGEPAGTDPGLDDLDVALSNLEVKLEGSAPTD 341
EEIDCTEEEM++FAALQYHI+KLS S E + AG + +D+++ ALSNLEV LEG
Sbjct: 303 EEIDCTEEEMLIFAALQYHISKLSLSAETQDFAG-ESEVDEIEAALSNLEVTLEGGKADS 361
Query: 342 VLDSLTTIPELKDHLRIFRIPRRPRKLTLKGYRQHWVVFKETTLSYYKSQDEAPGDPIQQ 401
+L+ +T IP+L D+L++FR P+KL K ++Q+W +FK+T+++Y+K+++ G+P+++
Sbjct: 362 LLEDITDIPKLADNLKLFR----PKKLLPKAFKQYWFIFKDTSIAYFKNKELEQGEPLEK 417
Query: 402 LNLKGCEVVPDVNVSGQKFCIKLLVPSPEGMSEIYLRCQDEQQYARWMAGCRLASKGRTM 461
LNL+GCEVVPDVNV+G+KF IKLL+P +GM+E+YLRC E QYA+WMA C LASKG+TM
Sbjct: 418 LNLRGCEVVPDVNVAGRKFGIKLLIPVADGMNEMYLRCDHENQYAQWMAACMLASKGKTM 477
Query: 462 ADSSYTSEVQAILAFLSLQRTGSGGPGNHPHGPDASAEGLNPYGLVAPRFQRKFKAKQLT 521
ADSSY EV IL+FL ++ S +NP V+PR ++ K+KQL
Sbjct: 478 ADSSYQPEVLNILSFLRMKNRNSASQV----ASSLENMDMNPECFVSPRCAKRHKSKQLA 533
Query: 522 PRILEAHQNVAQLSLAEAQLRFIQAWQSLPDFGISYVMVRFKGSRKDEILGIANNRLIRI 581
RILEAHQNVAQ+ L EA+LRFIQAWQSLP+FG++Y +VRFKGS+KD+ILG++ NRLI+I
Sbjct: 534 ARILEAHQNVAQMPLVEAKLRFIQAWQSLPEFGLTYYLVRFKGSKKDDILGVSYNRLIKI 593
Query: 582 DLAVGDVVKTWRFSNMRQWNVNWDIRQVAIEFDEHINVAFSCVSASCRIVHEYIGGYIFL 641
D A G V TWRF+N++QWNVNW+ RQV IEFD+++ AF+C+SA C+IVHEYIGGYIFL
Sbjct: 594 DAATGIPVTTWRFTNIKQWNVNWETRQVVIEFDQNVFTAFTCLSADCKIVHEYIGGYIFL 653
Query: 642 STRERARGEELDEDLFLQLTGGHE 665
STR + + E LDEDLF +LTGG +
Sbjct: 654 STRSKDQNETLDEDLFHKLTGGQD 677
>gi|201861813 fermitin family homolog 2 isoform 2 [Homo sapiens]
Length = 687
Score = 726 bits (1874), Expect = 0.0
Identities = 362/692 (52%), Positives = 496/692 (71%), Gaps = 42/692 (6%)
Query: 3 GMKTASGDYIDSSWELRVFVGEEDPEAESVTLRVTGESHIGGVLLKIVEQINRKQDWSDH 62
G++ G Y D +WEL V V + + + VTLRVTGE HIGGV+LK+VE+++ K+DWSDH
Sbjct: 5 GIRMPDGCYADGTWELSVHVTDLNRD---VTLRVTGEVHIGGVMLKLVEKLDVKKDWSDH 61
Query: 63 AIWWEQKRQWLLQTHWTLDKYGILADARLFFGPQHRPVILRLPNRRALRLRASFSQPLFQ 122
A+WWE+KR WLL+THWTLDKYGI ADA+L F PQH+ + L+LPN + ++++ +FS +F+
Sbjct: 62 ALWWEKKRTWLLKTHWTLDKYGIQADAKLQFTPQHKLLRLQLPNMKYVKVKVNFSDRVFK 121
Query: 123 AVAAICRLLSIRHPEELSLL---RAPEKKEKKKKEKEPEEELYDLSKVVLAGGV-----A 174
AV+ IC+ +IRHPEELSLL R P KK+KKK + + E+E +L ++ G +
Sbjct: 122 AVSDICKTFNIRHPEELSLLKKPRDPTKKKKKKLDDQSEDEALELEGPLITPGSGSIYSS 181
Query: 175 PALFR-----------GMP-----AHFSDSAQTEACYHMLSRPQPPPDPLLLQRLPRPSS 218
P L+ G P A F DSA +E +L+ QP P +L ++ +P +
Sbjct: 182 PGLYSKTMTPTYDAHDGSPLSPTSAWFGDSALSEGNPGILAVSQPITSPEILAKMFKPQA 241
Query: 219 LSDKTQLHSRWLDSSRCLMQQGIKAGDALWLRFKYYSFFDLDPKTDPVRLTQLYEQARWD 278
L DK +++ WLDSSR LM+Q +K +AL LRFKYYSFFDL+PK D +R+ QLYEQA+W
Sbjct: 242 LLDKAKINQGWLDSSRSLMEQDVKENEALLLRFKYYSFFDLNPKYDAIRINQLYEQAKWA 301
Query: 279 LLLEEIDCTEEEMMVFAALQYHINKLSQSGEVGEPAGTDPGLDDLDVALSNLEVKLEGSA 338
+LLEEI+CTEEEMM+FAALQYHINKLS +D +D++D ALS+LE+ LEG
Sbjct: 302 ILLEEIECTEEEMMMFAALQYHINKLSIMTSENHLNNSDKEVDEVDAALSDLEITLEGGK 361
Query: 339 PTDVLDSLTTIPELKDHLRIFRIPRRPRKLTLKGYRQHWVVFKETTLSYYKSQDEAPGDP 398
+ +L +T+IPEL D++++F+ P+KLTLKGY+Q+W FK+T++S YKS++E+ G P
Sbjct: 362 TSTILGDITSIPELADYIKVFK----PKKLTLKGYKQYWCTFKDTSISCYKSKEESSGTP 417
Query: 399 IQQLNLKGCEVVPDVNVSGQKFCIKLLVPSPEGMSEIYLRCQDEQQYARWMAGCRLASKG 458
Q+NL+GCEV PDVN+SGQKF IKLL+P EGM+EI+LRC +E+QYA WMA CRLASKG
Sbjct: 418 AHQMNLRGCEVTPDVNISGQKFNIKLLIPVAEGMNEIWLRCDNEKQYAHWMAACRLASKG 477
Query: 459 RTMADSSYTSEVQAILAFLSLQRTGSGGPGNHPHGPDASAEGLNPYGLVAPRFQRKFKAK 518
+TMADSSY EVQ IL+FL +Q + P+ + P LV+PR+ +K+K K
Sbjct: 478 KTMADSSYNLEVQNILSFLKMQHLNP----DPQLIPEQITTDITPECLVSPRYLKKYKNK 533
Query: 519 Q-------LTPRILEAHQNVAQLSLAEAQLRFIQAWQSLPDFGISYVMVRFKGSRKDEIL 571
Q +T RILEAHQNVAQ+SL EA++RFIQAWQSLP+FGI++ + RF+G +K+E++
Sbjct: 534 QPGYIRDLITARILEAHQNVAQMSLIEAKMRFIQAWQSLPEFGITHFIARFQGGKKEELI 593
Query: 572 GIANNRLIRIDLAVGDVVKTWRFSNMRQWNVNWDIRQVAIEFDEHINVAFSCVSASCRIV 631
GIA NRLIR+D + GD +KTWRFSNM+QWNVNW+I+ V +EF + + ++F C C++V
Sbjct: 594 GIAYNRLIRMDASTGDAIKTWRFSNMKQWNVNWEIKMVTVEFADEVRLSFICTEVDCKVV 653
Query: 632 HEYIGGYIFLSTRERARGEELDEDLFLQLTGG 663
HE+IGGYIFLSTR + + E LDE++F +LT G
Sbjct: 654 HEFIGGYIFLSTRAKDQNESLDEEMFYKLTSG 685
>gi|201861823 fermitin family homolog 2 isoform 3 [Homo sapiens]
Length = 633
Score = 664 bits (1712), Expect = 0.0
Identities = 336/638 (52%), Positives = 457/638 (71%), Gaps = 42/638 (6%)
Query: 3 GMKTASGDYIDSSWELRVFVGEEDPEAESVTLRVTGESHIGGVLLKIVEQINRKQDWSDH 62
G++ G Y D +WEL V V + + + VTLRVTGE HIGGV+LK+VE+++ K+DWSDH
Sbjct: 5 GIRMPDGCYADGTWELSVHVTDLNRD---VTLRVTGEVHIGGVMLKLVEKLDVKKDWSDH 61
Query: 63 AIWWEQKRQWLLQTHWTLDKYGILADARLFFGPQHRPVILRLPNRRALRLRASFSQPLFQ 122
A+WWE+KR WLL+THWTLDKYGI ADA+L F PQH+ + L+LPN + ++++ +FS +F+
Sbjct: 62 ALWWEKKRTWLLKTHWTLDKYGIQADAKLQFTPQHKLLRLQLPNMKYVKVKVNFSDRVFK 121
Query: 123 AVAAICRLLSIRHPEELSLL---RAPEKKEKKKKEKEPEEELYDLSKVVLAGGV-----A 174
AV+ IC+ +IRHPEELSLL R P KK+KKK + + E+E +L ++ G +
Sbjct: 122 AVSDICKTFNIRHPEELSLLKKPRDPTKKKKKKLDDQSEDEALELEGPLITPGSGSIYSS 181
Query: 175 PALFR-----------GMP-----AHFSDSAQTEACYHMLSRPQPPPDPLLLQRLPRPSS 218
P L+ G P A F DSA +E +L+ QP P +L ++ +P +
Sbjct: 182 PGLYSKTMTPTYDAHDGSPLSPTSAWFGDSALSEGNPGILAVSQPITSPEILAKMFKPQA 241
Query: 219 LSDKTQLHSRWLDSSRCLMQQGIKAGDALWLRFKYYSFFDLDPKTDPVRLTQLYEQARWD 278
L DK +++ WLDSSR LM+Q +K +AL LRFKYYSFFDL+PK D +R+ QLYEQA+W
Sbjct: 242 LLDKAKINQGWLDSSRSLMEQDVKENEALLLRFKYYSFFDLNPKYDAIRINQLYEQAKWA 301
Query: 279 LLLEEIDCTEEEMMVFAALQYHINKLSQSGEVGEPAGTDPGLDDLDVALSNLEVKLEGSA 338
+LLEEI+CTEEEMM+FAALQYHINKLS +D +D++D ALS+LE+ LEG
Sbjct: 302 ILLEEIECTEEEMMMFAALQYHINKLSIMTSENHLNNSDKEVDEVDAALSDLEITLEGGK 361
Query: 339 PTDVLDSLTTIPELKDHLRIFRIPRRPRKLTLKGYRQHWVVFKETTLSYYKSQDEAPGDP 398
+ +L +T+IPEL D++++F +P+KLTLKGY+Q+W FK+T++S YKS++E+ G P
Sbjct: 362 TSTILGDITSIPELADYIKVF----KPKKLTLKGYKQYWCTFKDTSISCYKSKEESSGTP 417
Query: 399 IQQLNLKGCEVVPDVNVSGQKFCIKLLVPSPEGMSEIYLRCQDEQQYARWMAGCRLASKG 458
Q+NL+GCEV PDVN+SGQKF IKLL+P EGM+EI+LRC +E+QYA WMA CRLASKG
Sbjct: 418 AHQMNLRGCEVTPDVNISGQKFNIKLLIPVAEGMNEIWLRCDNEKQYAHWMAACRLASKG 477
Query: 459 RTMADSSYTSEVQAILAFLSLQRTGSGGPGNHPHGPDASAEGLNPYGLVAPRFQRKFKAK 518
+TMADSSY EVQ IL+FL +Q + P+ + P LV+PR+ +K+K K
Sbjct: 478 KTMADSSYNLEVQNILSFLKMQHLNP----DPQLIPEQITTDITPECLVSPRYLKKYKNK 533
Query: 519 Q-------LTPRILEAHQNVAQLSLAEAQLRFIQAWQSLPDFGISYVMVRFKGSRKDEIL 571
Q +T RILEAHQNVAQ+SL EA++RFIQAWQSLP+FGI++ + RF+G +K+E++
Sbjct: 534 QPGYIRDLITARILEAHQNVAQMSLIEAKMRFIQAWQSLPEFGITHFIARFQGGKKEELI 593
Query: 572 GIANNRLIRIDLAVGDVVKTWRFSNMRQWNVNWDIRQV 609
GIA NRLIR+D + GD +KTWRFSNM+QWNVNW+I+ V
Sbjct: 594 GIAYNRLIRMDASTGDAIKTWRFSNMKQWNVNWEIKMV 631
>gi|223029410 talin 1 [Homo sapiens]
Length = 2541
Score = 63.9 bits (154), Expect = 4e-10
Identities = 44/180 (24%), Positives = 89/180 (49%), Gaps = 23/180 (12%)
Query: 488 GNHPHGPDASAE--GLNPYGLVAPRFQRKFKA-----KQLTPR----------ILEAHQN 530
G+HP D + E G P ++K KA K P+ I +AH+N
Sbjct: 226 GSHPVSFDKACEFAGFQCQIQFGPHNEQKHKAGFLDLKDFLPKEYVKQKGERKIFQAHKN 285
Query: 531 VAQLSLAEAQLRFIQAWQSLPDFGISYVMV--RFKGSRK--DEILGIANNRLIRIDLAVG 586
Q+S EA++R+++ +SL +G+S+ +V + KG K +LGI ++R+D
Sbjct: 286 CGQMSEIEAKVRYVKLARSLKTYGVSFFLVKEKMKGKNKLVPRLLGITKECVMRVDEKTK 345
Query: 587 DVVKTWRFSNMRQWNVNWDIRQVAIEFDEHINVAFSCVSASCRIVHEYIGGYIFLSTRER 646
+V++ W +N+++W + + ++F ++ + +S + + + I GYI + +++
Sbjct: 346 EVIQEWNLTNIKRWAAS--PKSFTLDFGDYQDGYYSVQTTEGEQIAQLIAGYIDIILKKK 403
Score = 46.6 bits (109), Expect = 7e-05
Identities = 57/238 (23%), Positives = 95/238 (39%), Gaps = 50/238 (21%)
Query: 67 EQKRQWLLQTHWTLDKYGILADARLFFGPQHRPVILRLPNRRALRLRASFSQPLFQAVAA 126
+ K+ L+ LD Y + + + + RP+ +R+ + + S+ + +
Sbjct: 55 DPKKGIWLEAGKALDYYMLRNGDTMEYRKKQRPLKIRMLDGTVKTIMVDDSKTVTDMLMT 114
Query: 127 ICRLLSIRHPEELSLLRAPEKKEKKKKEKEPEEELYDLSKVVLAGGVAPALFRGMPAHFS 186
IC + I + +E SL+R E E+KK+E + G +
Sbjct: 115 ICARIGITNHDEYSLVR--ELMEEKKEE--------------ITGTLRK----------- 147
Query: 187 DSAQTEACYHMLSRPQPPPDPLLLQRLPRPSSLSDK--TQLHSRWLDSSRCLMQQGIKAG 244
D LL+ + L K T WLD R L +QG++
Sbjct: 148 -------------------DKTLLRDEKKMEKLKQKLHTDDELNWLDHGRTLREQGVEEH 188
Query: 245 DALWLRFK-YYSFFDLDPKTDPVRLTQLYEQARWDLLLEEIDCTEEEMMVFAALQYHI 301
+ L LR K +YS ++D + DPV+L LY QAR D+L + ++ FA Q I
Sbjct: 189 ETLLLRRKFFYSDQNVDSR-DPVQLNLLYVQARDDILNGSHPVSFDKACEFAGFQCQI 245
>gi|156938343 talin 2 [Homo sapiens]
Length = 2542
Score = 58.9 bits (141), Expect = 1e-08
Identities = 31/135 (22%), Positives = 73/135 (54%), Gaps = 6/135 (4%)
Query: 516 KAKQLTPRILEAHQNVAQLSLAEAQLRFIQAWQSLPDFGISYVMV--RFKGSRK--DEIL 571
K + RI + H+N ++S EA++++++ +SL +G+S+ +V + KG K +L
Sbjct: 274 KQRGAEKRIFQEHKNCGEMSEIEAKVKYVKLARSLRTYGVSFFLVKEKMKGKNKLVPRLL 333
Query: 572 GIANNRLIRIDLAVGDVVKTWRFSNMRQWNVNWDIRQVAIEFDEHINVAFSCVSASCRIV 631
GI + ++R+D +V++ W + +++W + + ++F E+ +S + +
Sbjct: 334 GITKDSVMRVDEKTKEVLQEWPLTTVKRWAAS--PKSFTLDFGEYQESYYSVQTTEGEQI 391
Query: 632 HEYIGGYIFLSTRER 646
+ I GYI + +++
Sbjct: 392 SQLIAGYIDIILKKK 406
Score = 46.2 bits (108), Expect = 1e-04
Identities = 74/285 (25%), Positives = 112/285 (39%), Gaps = 76/285 (26%)
Query: 22 VGEEDPEAESVTLRVTGESHIGGVLLKIVEQINRKQDWSDHAIWWEQKRQWLLQTHWTLD 81
+ E PEA+ TG++ G+ L ++ RK IW E R TLD
Sbjct: 34 IRERVPEAQ------TGQASDYGLFLS--DEDPRK------GIWLEAGR--------TLD 71
Query: 82 KYGILADARLFFGPQHRPVILRLPNRRALRLRASFSQPLFQAVAAICRLLSIRHPEELSL 141
Y + L + + RP +R+ + + S+ + + + IC + I + EE SL
Sbjct: 72 YYMLRNGDILEYKKKQRPQKIRMLDGSVKTVMVDDSKTVGELLVTICSRIGITNYEEYSL 131
Query: 142 LRAPEKKEKKKKEKEPEEELYDLSKVVLAGGVAPALFRGMPAHFSDSAQTEACYHMLSRP 201
++ E E+KK EE L K
Sbjct: 132 IQ--ETIEEKK-----EEGTGTLKK----------------------------------- 149
Query: 202 QPPPDPLLLQRLPRPSSLSDKTQLHS----RWLDSSRCLMQQGIKAGDALWLRFK-YYSF 256
D LL+ + L K +LH+ WLD SR +QG+ + L LR K +YS
Sbjct: 150 ----DRTLLRDERKMEKL--KAKLHTDDDLNWLDHSRTFREQGVDENETLLLRRKFFYSD 203
Query: 257 FDLDPKTDPVRLTQLYEQARWDLLLEEIDCTEEEMMVFAALQYHI 301
++D + DPV+L LY QAR D+L + E+ F Q I
Sbjct: 204 QNVDSR-DPVQLNLLYVQARDDILNGSHPVSFEKACEFGGFQAQI 247
>gi|4505531 oxysterol binding protein [Homo sapiens]
Length = 807
Score = 37.0 bits (84), Expect = 0.059
Identities = 24/106 (22%), Positives = 49/106 (46%), Gaps = 10/106 (9%)
Query: 370 LKGYRQHWVVFKETTLSYYKSQDEAPGDPIQQLNLKGCEVVPDVNVSGQKFCIKLLVPSP 429
+KGY++ W V LSYY+S+ E + +G + N++ + C ++ S
Sbjct: 102 IKGYQRRWFVLSNGLLSYYRSKAE------MRHTCRGTINLATANITVEDSCNFII--SN 153
Query: 430 EGMSEIYLRCQDEQQYARWMAGCRLASKG--RTMADSSYTSEVQAI 473
G +L+ E + RW+ LA + +A+S + + +++
Sbjct: 154 GGAQTYHLKASSEVERQRWVTALELAKAKAVKMLAESDESGDEESV 199
>gi|14165452 alpha 3 type IV collagen binding protein isoform 2
[Homo sapiens]
Length = 598
Score = 36.6 bits (83), Expect = 0.077
Identities = 34/126 (26%), Positives = 45/126 (35%), Gaps = 41/126 (32%)
Query: 370 LKGYRQHWVVFKETTLSYYKSQDEAPGDPIQQLNLKGCEVVPDVNVSGQKFCIKLLVPSP 429
+ G++ WVV K LSYYKS+DE GC C+ V +P
Sbjct: 37 IHGWQDRWVVLKNNALSYYKSEDETE---------YGCR---------GSICLSKAVITP 78
Query: 430 EGMSEI-----------YLRCQDEQQYARWMAGCRLASKGRTMADSSYTSEVQAILAFLS 478
E YLR QD +W+ + +S Y SE S
Sbjct: 79 HDFDECRFDISVNDSVWYLRAQDPDHRQQWIDAIE-----QHKTESGYGSE-------SS 126
Query: 479 LQRTGS 484
L+R GS
Sbjct: 127 LRRHGS 132
>gi|194294543 alpha 3 type IV collagen binding protein isoform 3
[Homo sapiens]
Length = 752
Score = 36.6 bits (83), Expect = 0.077
Identities = 34/126 (26%), Positives = 45/126 (35%), Gaps = 41/126 (32%)
Query: 370 LKGYRQHWVVFKETTLSYYKSQDEAPGDPIQQLNLKGCEVVPDVNVSGQKFCIKLLVPSP 429
+ G++ WVV K LSYYKS+DE GC C+ V +P
Sbjct: 165 IHGWQDRWVVLKNNALSYYKSEDETE---------YGCR---------GSICLSKAVITP 206
Query: 430 EGMSEI-----------YLRCQDEQQYARWMAGCRLASKGRTMADSSYTSEVQAILAFLS 478
E YLR QD +W+ + +S Y SE S
Sbjct: 207 HDFDECRFDISVNDSVWYLRAQDPDHRQQWIDAIE-----QHKTESGYGSE-------SS 254
Query: 479 LQRTGS 484
L+R GS
Sbjct: 255 LRRHGS 260
>gi|5031717 alpha 3 type IV collagen binding protein isoform 1 [Homo
sapiens]
Length = 624
Score = 36.6 bits (83), Expect = 0.077
Identities = 34/126 (26%), Positives = 45/126 (35%), Gaps = 41/126 (32%)
Query: 370 LKGYRQHWVVFKETTLSYYKSQDEAPGDPIQQLNLKGCEVVPDVNVSGQKFCIKLLVPSP 429
+ G++ WVV K LSYYKS+DE GC C+ V +P
Sbjct: 37 IHGWQDRWVVLKNNALSYYKSEDETE---------YGCR---------GSICLSKAVITP 78
Query: 430 EGMSEI-----------YLRCQDEQQYARWMAGCRLASKGRTMADSSYTSEVQAILAFLS 478
E YLR QD +W+ + +S Y SE S
Sbjct: 79 HDFDECRFDISVNDSVWYLRAQDPDHRQQWIDAIE-----QHKTESGYGSE-------SS 126
Query: 479 LQRTGS 484
L+R GS
Sbjct: 127 LRRHGS 132
>gi|54792084 pleckstrin homology domain containing, family A
(phosphoinositide binding specific) member 3 [Homo
sapiens]
Length = 300
Score = 35.0 bits (79), Expect = 0.22
Identities = 25/106 (23%), Positives = 44/106 (41%), Gaps = 12/106 (11%)
Query: 370 LKGYRQHWVVFKETTLSYYKSQDEAPGDPIQQLNLKGCEVVPDVNVSGQKFCIKLLVPSP 429
L G++ W V LSYY SQD+ + + CE+ S ++L++P
Sbjct: 12 LTGWQPRWFVLDNGILSYYDSQDDVCKGSKGSIKMAVCEIKVH---SADNTRMELIIP-- 66
Query: 430 EGMSEIYLRCQDEQQYARWMA------GCRLASKGRTMADSSYTSE 469
G Y++ + + RW+ C ++ + + S TSE
Sbjct: 67 -GEQHFYMKAVNAAERQRWLVALGSSKACLTDTRTKKEKEISETSE 111
>gi|5031633 FERM, RhoGEF, and pleckstrin domain protein 1 isoform 1
[Homo sapiens]
Length = 1045
Score = 34.7 bits (78), Expect = 0.29
Identities = 27/87 (31%), Positives = 41/87 (47%), Gaps = 8/87 (9%)
Query: 372 GYRQHWVVFKETTLSYYKSQDEAPGDPIQQLNLKGCEV-VPDVNVSGQK-FCIKLLVPSP 429
G+++ WVVF L +YKS + P+ L L G + +P + + QK + KL S
Sbjct: 948 GWQKLWVVFTNFCLFFYKSHQD--NHPLASLPLLGYSLTIPSESENIQKDYVFKLHFKS- 1004
Query: 430 EGMSEIYLRCQDEQQYARWMAGCRLAS 456
Y R + E + RWM R A+
Sbjct: 1005 ---HVYYFRAESEYTFERWMEVIRSAT 1028
>gi|56118221 amyloid beta (A4) precursor protein-binding, family B,
member 1 interacting protein [Homo sapiens]
Length = 666
Score = 34.3 bits (77), Expect = 0.38
Identities = 22/79 (27%), Positives = 37/79 (46%), Gaps = 4/79 (5%)
Query: 420 FCIKLLVPSPEGMSEI--YLRCQDEQQYARWMAGCRLASKGRTMADSSYTSEVQAILA-- 475
+C L P + S+ YL C D + +W+ G R+A G+T+ D+ + +A LA
Sbjct: 380 YCFVLKHPQIQKESQYIKYLCCDDTRTLNQWVMGIRIAKYGKTLYDNYQRAVAKAGLASR 439
Query: 476 FLSLQRTGSGGPGNHPHGP 494
+ +L + P GP
Sbjct: 440 WTNLGTVNAAAPAQPSTGP 458
>gi|22027480 pogo transposable element with KRAB domain [Homo
sapiens]
Length = 609
Score = 34.3 bits (77), Expect = 0.38
Identities = 34/113 (30%), Positives = 51/113 (45%), Gaps = 21/113 (18%)
Query: 132 SIRHPEELSLLRAPEKKEKKKKEKEPEEELYDLSKVVLA--GGVAPALFRGMPAHFSD-- 187
S +P LSL E++E++ + +E E+ D+ KV + GG PALF + +FSD
Sbjct: 3 STAYPLNLSLKE--EEEEEEIQSRELEDGPADMQKVRICSEGGWVPALFDEVAIYFSDEE 60
Query: 188 ----SAQTEACYHMLSR-----------PQPPPDPLLLQRLPRPSSLSDKTQL 225
+ Q +A Y + R P P PD + S SD+ QL
Sbjct: 61 WEVLTEQQKALYREVMRMNYETVLSLEFPFPKPDMITRLEGEEESQNSDEWQL 113
>gi|13540513 oxysterol binding protein 2 isoform a [Homo sapiens]
Length = 916
Score = 33.5 bits (75), Expect = 0.65
Identities = 23/86 (26%), Positives = 35/86 (40%), Gaps = 9/86 (10%)
Query: 370 LKGYRQHWVVFKETTLSYYKSQDEAPGDPIQQLNLKGCEVVPDVNVSGQKFCIKLLVPSP 429
LKGY++ W V LSYY++Q E +NL ++ + C LL
Sbjct: 196 LKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLS------TAHIDTEDSCGILLT--- 246
Query: 430 EGMSEIYLRCQDEQQYARWMAGCRLA 455
G +L+ E +W+ LA
Sbjct: 247 SGARSYHLKASSEVDRQQWITALELA 272
>gi|4502435 BMX non-receptor tyrosine kinase [Homo sapiens]
Length = 675
Score = 33.1 bits (74), Expect = 0.85
Identities = 29/149 (19%), Positives = 62/149 (41%), Gaps = 10/149 (6%)
Query: 343 LDSLTTIPELKDHLRIFRIPRRPRKLTLKGYRQHWVVFKETTLSYYKSQDEAPGDPIQQL 402
+D+ + + EL + + ++ +K++ Y++ V +T LSYY+ G +
Sbjct: 1 MDTKSILEEL-----LLKRSQQKKKMSPNNYKERLFVLTKTNLSYYEYDKMKRGSRKGSI 55
Query: 403 NLKGCEVVPDVNVSGQ---KFCIKLLVPSPEGMSEIYLRCQDEQQYARWMAGCRLASKGR 459
+K V VN+ Q + + +G+ +Y+ +E+ ++W+ + +G
Sbjct: 56 EIKKIRCVEKVNLEEQTPVERQYPFQIVYKDGL--LYVYASNEESRSQWLKALQKEIRGN 113
Query: 460 TMADSSYTSEVQAILAFLSLQRTGSGGPG 488
Y S FL Q++ PG
Sbjct: 114 PHLLVKYHSGFFVDGKFLCCQQSCKAAPG 142
>gi|42544182 BMX non-receptor tyrosine kinase [Homo sapiens]
Length = 675
Score = 33.1 bits (74), Expect = 0.85
Identities = 29/149 (19%), Positives = 62/149 (41%), Gaps = 10/149 (6%)
Query: 343 LDSLTTIPELKDHLRIFRIPRRPRKLTLKGYRQHWVVFKETTLSYYKSQDEAPGDPIQQL 402
+D+ + + EL + + ++ +K++ Y++ V +T LSYY+ G +
Sbjct: 1 MDTKSILEEL-----LLKRSQQKKKMSPNNYKERLFVLTKTNLSYYEYDKMKRGSRKGSI 55
Query: 403 NLKGCEVVPDVNVSGQ---KFCIKLLVPSPEGMSEIYLRCQDEQQYARWMAGCRLASKGR 459
+K V VN+ Q + + +G+ +Y+ +E+ ++W+ + +G
Sbjct: 56 EIKKIRCVEKVNLEEQTPVERQYPFQIVYKDGL--LYVYASNEESRSQWLKALQKEIRGN 113
Query: 460 TMADSSYTSEVQAILAFLSLQRTGSGGPG 488
Y S FL Q++ PG
Sbjct: 114 PHLLVKYHSGFFVDGKFLCCQQSCKAAPG 142
>gi|239745081 PREDICTED: similar to Golgin subfamily A member 8-like
protein 1 isoform 2 [Homo sapiens]
Length = 629
Score = 33.1 bits (74), Expect = 0.85
Identities = 29/118 (24%), Positives = 49/118 (41%), Gaps = 10/118 (8%)
Query: 457 KGRTMADSSYTSEVQAILAFLSLQRTGSGGPGNHPHGPDASAEGLNPYGLVAPRFQRKFK 516
K R A S ++ A L+ ++L G GG G +A P + +
Sbjct: 397 KERLEAASQQKQQLTAQLSLMALPGEGDGGGHLDSEGEEAPRP--------IPSIPQDLE 448
Query: 517 AKQLTPRILEAHQNVAQLS--LAEAQLRFIQAWQSLPDFGISYVMVRFKGSRKDEILG 572
+++ ++ + A LS + + +LRFIQ WQ I +++ G KD LG
Sbjct: 449 SREAMSSFMDHLEEKADLSELVKKQELRFIQYWQERCHQKIHHLLSEPGGRAKDAALG 506
>gi|197382472 actin filament associated protein 1 isoform a [Homo
sapiens]
Length = 814
Score = 32.0 bits (71), Expect = 1.9
Identities = 23/86 (26%), Positives = 38/86 (44%), Gaps = 6/86 (6%)
Query: 373 YRQHWVVFKETTLSYYKSQDEAPGDPIQQLNLKGCEVVPDVNVSGQKFCIKLLVPSPEGM 432
+R+ W K+ L ++K + + I + L+GCEV+P ++ S +LL G
Sbjct: 362 WRERWCRVKDNKLIFHKDRTDLKTH-IVSIPLRGCEVIPGLD-SKHPLTFRLL---RNGQ 416
Query: 433 SEIYLRCQDEQQYARWMAGCRLASKG 458
L + RW+ G LA G
Sbjct: 417 EVAVLEASSSEDMGRWI-GILLAETG 441
>gi|40807504 actin filament associated protein 1 [Homo sapiens]
Length = 730
Score = 32.0 bits (71), Expect = 1.9
Identities = 23/86 (26%), Positives = 38/86 (44%), Gaps = 6/86 (6%)
Query: 373 YRQHWVVFKETTLSYYKSQDEAPGDPIQQLNLKGCEVVPDVNVSGQKFCIKLLVPSPEGM 432
+R+ W K+ L ++K + + I + L+GCEV+P ++ S +LL G
Sbjct: 362 WRERWCRVKDNKLIFHKDRTDLKTH-IVSIPLRGCEVIPGLD-SKHPLTFRLL---RNGQ 416
Query: 433 SEIYLRCQDEQQYARWMAGCRLASKG 458
L + RW+ G LA G
Sbjct: 417 EVAVLEASSSEDMGRWI-GILLAETG 441
>gi|50355978 T-cell leukemia homeobox 3 [Homo sapiens]
Length = 291
Score = 31.6 bits (70), Expect = 2.5
Identities = 23/86 (26%), Positives = 34/86 (39%), Gaps = 13/86 (15%)
Query: 175 PALFRGMPAHFSDSAQTEA-------------CYHMLSRPQPPPDPLLLQRLPRPSSLSD 221
PA F G+ A F D+ + L PPP P L +P ++S
Sbjct: 60 PASFAGLGAPFEDAGSYSVNLSLAPAGVIRVPAHRPLPGAVPPPLPSALPAMPSVPTVSS 119
Query: 222 KTQLHSRWLDSSRCLMQQGIKAGDAL 247
L+ W++SSR ++ A AL
Sbjct: 120 LGGLNFPWMESSRRFVKDRFTAAAAL 145
>gi|154354979 myosin X [Homo sapiens]
Length = 2058
Score = 30.8 bits (68), Expect = 4.2
Identities = 22/60 (36%), Positives = 29/60 (48%), Gaps = 4/60 (6%)
Query: 242 KAGDALW-LRFKYYSFFDLD--PKTDPVRLTQLYEQARWDLLLEEIDCTEEEMMVFAALQ 298
+ GD W FK Y F D D PK D V ++EQA ++ EE + V AAL+
Sbjct: 1776 EVGDLPWKFYFKLYCFLDTDNVPK-DSVEFAFMFEQAHEAVIHGHHPAPEENLQVLAALR 1834
>gi|51243032 oxysterol-binding protein-like protein 8 isoform b
[Homo sapiens]
Length = 847
Score = 30.8 bits (68), Expect = 4.2
Identities = 29/109 (26%), Positives = 40/109 (36%), Gaps = 23/109 (21%)
Query: 369 TLKGYRQHWVVFKETTLSYYKSQDEAPGDPIQQLNLKGCEVVPDVNVSGQKFCIKLLVP- 427
TLK + + W V K L YK+Q G + + L CE++ + FC KL P
Sbjct: 118 TLKSWTKLWCVLKPGVLLIYKTQKN--GQWVGTVLLNACEIIERPS-KKDGFCFKLFHPL 174
Query: 428 --------SPEG-----------MSEIYLRCQDEQQYARWMAGCRLASK 457
P+G S + +R E WM LA K
Sbjct: 175 EQSIWAVKGPKGEAVGSITQPLPSSYLIIRATSESDGRCWMDALELALK 223
>gi|18079218 oxysterol-binding protein-like protein 8 isoform a
[Homo sapiens]
Length = 889
Score = 30.8 bits (68), Expect = 4.2
Identities = 29/109 (26%), Positives = 40/109 (36%), Gaps = 23/109 (21%)
Query: 369 TLKGYRQHWVVFKETTLSYYKSQDEAPGDPIQQLNLKGCEVVPDVNVSGQKFCIKLLVP- 427
TLK + + W V K L YK+Q G + + L CE++ + FC KL P
Sbjct: 160 TLKSWTKLWCVLKPGVLLIYKTQKN--GQWVGTVLLNACEIIERPS-KKDGFCFKLFHPL 216
Query: 428 --------SPEG-----------MSEIYLRCQDEQQYARWMAGCRLASK 457
P+G S + +R E WM LA K
Sbjct: 217 EQSIWAVKGPKGEAVGSITQPLPSSYLIIRATSESDGRCWMDALELALK 265
>gi|157266334 tubby like protein 1 [Homo sapiens]
Length = 542
Score = 30.8 bits (68), Expect = 4.2
Identities = 24/94 (25%), Positives = 42/94 (44%), Gaps = 5/94 (5%)
Query: 134 RHPEELSLL-RAPEKKEKKKKEKE----PEEELYDLSKVVLAGGVAPALFRGMPAHFSDS 188
R P E L+ RAP+ ++++++E+E EEE + + +L P +
Sbjct: 100 RDPRETFLVARAPDAEDEEEEEEEDEEDEEEEAEEKKEKILLPPKKPLREKSSADLKERR 159
Query: 189 AQTEACYHMLSRPQPPPDPLLLQRLPRPSSLSDK 222
A+ + L P PPP PL ++ P+ K
Sbjct: 160 AKAQGPRGDLGSPDPPPKPLRVRNKEAPAGEGTK 193
>gi|110346438 FERM and PDZ domain containing 2 isoform 1 [Homo
sapiens]
Length = 1287
Score = 30.8 bits (68), Expect = 4.2
Identities = 26/115 (22%), Positives = 49/115 (42%), Gaps = 6/115 (5%)
Query: 488 GNHPHGPDASAEGLNPYGLVAPRFQRKFKAKQLTPRILEAHQNVAQLSLAEAQLRFIQAW 547
GN+P S + + + A ++ + E H+ + L +A+L+F++
Sbjct: 458 GNYPKEQVESKPYFHVEDYIPASLIERMTALRVQVEVSEMHRLSSALWGEDAELKFLRVT 517
Query: 548 QSLPDFGISYVMVRFKGSRKDE--ILGIANNRLIRIDLAVGDVVKTWRFSNMRQW 600
Q LP++G+ V + R +E LGI +I ++ + RF QW
Sbjct: 518 QQLPEYGVLVHQVFSEKRRPEEEMALGICAKGVIVYEVKNNSRIAMLRF----QW 568
>gi|110346436 FERM and PDZ domain containing 2 isoform 3 [Homo
sapiens]
Length = 1309
Score = 30.8 bits (68), Expect = 4.2
Identities = 26/115 (22%), Positives = 49/115 (42%), Gaps = 6/115 (5%)
Query: 488 GNHPHGPDASAEGLNPYGLVAPRFQRKFKAKQLTPRILEAHQNVAQLSLAEAQLRFIQAW 547
GN+P S + + + A ++ + E H+ + L +A+L+F++
Sbjct: 480 GNYPKEQVESKPYFHVEDYIPASLIERMTALRVQVEVSEMHRLSSALWGEDAELKFLRVT 539
Query: 548 QSLPDFGISYVMVRFKGSRKDE--ILGIANNRLIRIDLAVGDVVKTWRFSNMRQW 600
Q LP++G+ V + R +E LGI +I ++ + RF QW
Sbjct: 540 QQLPEYGVLVHQVFSEKRRPEEEMALGICAKGVIVYEVKNNSRIAMLRF----QW 590
>gi|113425145 PREDICTED: similar to Golgin subfamily A member 8-like
protein 2 isoform 3 [Homo sapiens]
Length = 632
Score = 30.4 bits (67), Expect = 5.5
Identities = 27/113 (23%), Positives = 46/113 (40%), Gaps = 10/113 (8%)
Query: 462 ADSSYTSEVQAILAFLSLQRTGSGGPGNHPHGPDASAEGLNPYGLVAPRFQRKFKAKQLT 521
A S ++ A L+ ++L G GG G +A P ++++
Sbjct: 405 AASQQNQQLTAQLSLMALPGEGHGGEHLDSEGEEAPQP--------MPSVPEDLESREAM 456
Query: 522 PRILEAHQNVAQLS--LAEAQLRFIQAWQSLPDFGISYVMVRFKGSRKDEILG 572
++ + A LS + + +LRFIQ WQ I +++ G KD LG
Sbjct: 457 SSFMDHLKEKADLSELVKKQELRFIQYWQERCHQKIHHLLSEPGGRAKDAALG 509
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.416
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,894,513
Number of Sequences: 37866
Number of extensions: 1366874
Number of successful extensions: 5921
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 28
Number of HSP's that attempted gapping in prelim test: 5847
Number of HSP's gapped (non-prelim): 81
length of query: 667
length of database: 18,247,518
effective HSP length: 109
effective length of query: 558
effective length of database: 14,120,124
effective search space: 7879029192
effective search space used: 7879029192
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.