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Search of human proteins with 40807477
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40807477 retinoic acid induced 1 [Homo sapiens]
(1906 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40807477 retinoic acid induced 1 [Homo sapiens] 3901 0.0
gi|31652242 transcription factor 20 isoform 2 [Homo sapiens] 249 2e-65
gi|31652244 transcription factor 20 isoform 1 [Homo sapiens] 249 2e-65
gi|163965366 nascent polypeptide-associated complex alpha subuni... 76 4e-13
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 73 3e-12
gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [... 71 9e-12
gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo s... 70 3e-11
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 67 2e-10
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 65 6e-10
gi|55750053 atrophin-1 [Homo sapiens] 64 1e-09
gi|55750041 atrophin-1 [Homo sapiens] 64 1e-09
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 62 4e-09
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] 60 2e-08
gi|114431248 hypothetical protein LOC205717 [Homo sapiens] 58 1e-07
gi|38787935 BMP-2 inducible kinase isoform a [Homo sapiens] 58 1e-07
gi|38787904 BMP-2 inducible kinase isoform b [Homo sapiens] 58 1e-07
gi|122937241 SH3 and multiple ankyrin repeat domains 3 [Homo sap... 56 3e-07
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 56 3e-07
gi|110347429 mediator complex subunit 12 [Homo sapiens] 56 3e-07
gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens] 56 3e-07
gi|82534351 microtubule-associated protein tau isoform 1 [Homo s... 56 4e-07
gi|56549696 E1A binding protein p400 [Homo sapiens] 55 5e-07
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 55 9e-07
gi|33286444 mastermind-like 2 [Homo sapiens] 54 1e-06
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 54 1e-06
gi|178557734 microtubule-associated protein tau isoform 6 [Homo ... 54 1e-06
gi|55956910 meningioma 1 [Homo sapiens] 54 1e-06
gi|189491748 ataxin 1 [Homo sapiens] 54 2e-06
gi|51479158 ataxin 1 [Homo sapiens] 54 2e-06
gi|169167967 PREDICTED: hypothetical protein [Homo sapiens] 54 2e-06
>gi|40807477 retinoic acid induced 1 [Homo sapiens]
Length = 1906
Score = 3901 bits (10117), Expect = 0.0
Identities = 1906/1906 (100%), Positives = 1906/1906 (100%)
Query: 1 MQSFRERCGFHGKQQNYQQTSQETSRLENYRQPSQAGLSCDRQRLLAKDYYNPQPYPSYE 60
MQSFRERCGFHGKQQNYQQTSQETSRLENYRQPSQAGLSCDRQRLLAKDYYNPQPYPSYE
Sbjct: 1 MQSFRERCGFHGKQQNYQQTSQETSRLENYRQPSQAGLSCDRQRLLAKDYYNPQPYPSYE 60
Query: 61 GGAGTPSGTAAAVAADKYHRGSKALPTQQGLQGRPAFPGYGVQDSSPYPGRYAGEESLQA 120
GGAGTPSGTAAAVAADKYHRGSKALPTQQGLQGRPAFPGYGVQDSSPYPGRYAGEESLQA
Sbjct: 61 GGAGTPSGTAAAVAADKYHRGSKALPTQQGLQGRPAFPGYGVQDSSPYPGRYAGEESLQA 120
Query: 121 WGAPQPPPPQPQPLPAGVAKYDENLMKKTAVPPSRQYAEQGAQVPFRTHSLHVQQPPPPQ 180
WGAPQPPPPQPQPLPAGVAKYDENLMKKTAVPPSRQYAEQGAQVPFRTHSLHVQQPPPPQ
Sbjct: 121 WGAPQPPPPQPQPLPAGVAKYDENLMKKTAVPPSRQYAEQGAQVPFRTHSLHVQQPPPPQ 180
Query: 181 QPLAYPKLQRQKLQNDIASPLPFPQGTHFPQHSQSFPTSSTYSSSVQGGGQGAHSYKSCT 240
QPLAYPKLQRQKLQNDIASPLPFPQGTHFPQHSQSFPTSSTYSSSVQGGGQGAHSYKSCT
Sbjct: 181 QPLAYPKLQRQKLQNDIASPLPFPQGTHFPQHSQSFPTSSTYSSSVQGGGQGAHSYKSCT 240
Query: 241 APTAQPHDRPLTASSSLAPGQRVQNLHAYQSGRLSYDQQQQQQQQQQQQQQALQSRHHAQ 300
APTAQPHDRPLTASSSLAPGQRVQNLHAYQSGRLSYDQQQQQQQQQQQQQQALQSRHHAQ
Sbjct: 241 APTAQPHDRPLTASSSLAPGQRVQNLHAYQSGRLSYDQQQQQQQQQQQQQQALQSRHHAQ 300
Query: 301 ETLHYQNLAKYQHYGQQGQGYCQPDAAVRTPEQYYQTFSPSSSHSPARSVGRSPSYSSTP 360
ETLHYQNLAKYQHYGQQGQGYCQPDAAVRTPEQYYQTFSPSSSHSPARSVGRSPSYSSTP
Sbjct: 301 ETLHYQNLAKYQHYGQQGQGYCQPDAAVRTPEQYYQTFSPSSSHSPARSVGRSPSYSSTP 360
Query: 361 SPLMPNLENFPYSQQPLSTGAFPAGITDHSHFMPLLNPSPTDATSSVDTQAGNCKPLQKD 420
SPLMPNLENFPYSQQPLSTGAFPAGITDHSHFMPLLNPSPTDATSSVDTQAGNCKPLQKD
Sbjct: 361 SPLMPNLENFPYSQQPLSTGAFPAGITDHSHFMPLLNPSPTDATSSVDTQAGNCKPLQKD 420
Query: 421 KLPENLLSDLSLQSLTALTSQVENISNTVQQLLLSKAAVPQKKGVKNLVSRTPEQHKSQH 480
KLPENLLSDLSLQSLTALTSQVENISNTVQQLLLSKAAVPQKKGVKNLVSRTPEQHKSQH
Sbjct: 421 KLPENLLSDLSLQSLTALTSQVENISNTVQQLLLSKAAVPQKKGVKNLVSRTPEQHKSQH 480
Query: 481 CSPEGSGYSAEPAGTPLSEPPSSTPQSTHAEPQEADYLSGSEDPLERSFLYCNQARGSPA 540
CSPEGSGYSAEPAGTPLSEPPSSTPQSTHAEPQEADYLSGSEDPLERSFLYCNQARGSPA
Sbjct: 481 CSPEGSGYSAEPAGTPLSEPPSSTPQSTHAEPQEADYLSGSEDPLERSFLYCNQARGSPA 540
Query: 541 RVNSNSKAKPESVSTCSVTSPDDMSTKSDDSFQSLHGSLPLDSFSKFVAGERDCPRLLLS 600
RVNSNSKAKPESVSTCSVTSPDDMSTKSDDSFQSLHGSLPLDSFSKFVAGERDCPRLLLS
Sbjct: 541 RVNSNSKAKPESVSTCSVTSPDDMSTKSDDSFQSLHGSLPLDSFSKFVAGERDCPRLLLS 600
Query: 601 ALAQEDLASEILGLQEAIGEKADKAWAEAPSLVKDSSKPPFSLENHSACLDSVAKSAWPR 660
ALAQEDLASEILGLQEAIGEKADKAWAEAPSLVKDSSKPPFSLENHSACLDSVAKSAWPR
Sbjct: 601 ALAQEDLASEILGLQEAIGEKADKAWAEAPSLVKDSSKPPFSLENHSACLDSVAKSAWPR 660
Query: 661 PGEPEALPDSLQLDKGGNAKDFSPGLFEDPSVAFATPDPKKTTGPLSFGTKPTLGVPAPD 720
PGEPEALPDSLQLDKGGNAKDFSPGLFEDPSVAFATPDPKKTTGPLSFGTKPTLGVPAPD
Sbjct: 661 PGEPEALPDSLQLDKGGNAKDFSPGLFEDPSVAFATPDPKKTTGPLSFGTKPTLGVPAPD 720
Query: 721 PTTAAFDCFPDTTAASSADSANPFAWPEENLGDACPRWGLHPGELTKGLEQGGKASDGIS 780
PTTAAFDCFPDTTAASSADSANPFAWPEENLGDACPRWGLHPGELTKGLEQGGKASDGIS
Sbjct: 721 PTTAAFDCFPDTTAASSADSANPFAWPEENLGDACPRWGLHPGELTKGLEQGGKASDGIS 780
Query: 781 KGDTHEASACLGFQEEDPPGEKVASLPGDFKQEEVGGVKEEAGGLLQCPEVAKADRWLED 840
KGDTHEASACLGFQEEDPPGEKVASLPGDFKQEEVGGVKEEAGGLLQCPEVAKADRWLED
Sbjct: 781 KGDTHEASACLGFQEEDPPGEKVASLPGDFKQEEVGGVKEEAGGLLQCPEVAKADRWLED 840
Query: 841 SRHCCSTADFGDLPLLPPTSRKEDLEAEEEYSSLCELLGSPEQRPGMQDPLSPKAPLICT 900
SRHCCSTADFGDLPLLPPTSRKEDLEAEEEYSSLCELLGSPEQRPGMQDPLSPKAPLICT
Sbjct: 841 SRHCCSTADFGDLPLLPPTSRKEDLEAEEEYSSLCELLGSPEQRPGMQDPLSPKAPLICT 900
Query: 901 KEEVEEVLDSKAGWGSPCHLSGESVILLGPTVGTESKVQSWFESSLSHMKPGEEGPDGER 960
KEEVEEVLDSKAGWGSPCHLSGESVILLGPTVGTESKVQSWFESSLSHMKPGEEGPDGER
Sbjct: 901 KEEVEEVLDSKAGWGSPCHLSGESVILLGPTVGTESKVQSWFESSLSHMKPGEEGPDGER 960
Query: 961 APGDSTTSDASLAQKPNKPAVPEAPIAKKEPVPRGKSLRSRRVHRGLPEAEDSPCRAPVL 1020
APGDSTTSDASLAQKPNKPAVPEAPIAKKEPVPRGKSLRSRRVHRGLPEAEDSPCRAPVL
Sbjct: 961 APGDSTTSDASLAQKPNKPAVPEAPIAKKEPVPRGKSLRSRRVHRGLPEAEDSPCRAPVL 1020
Query: 1021 PKDLLLPESCTGPPQGQMEGAGAPGRGASEGLPRMCTRSLTALSEPRTPGPPGLTTTPAP 1080
PKDLLLPESCTGPPQGQMEGAGAPGRGASEGLPRMCTRSLTALSEPRTPGPPGLTTTPAP
Sbjct: 1021 PKDLLLPESCTGPPQGQMEGAGAPGRGASEGLPRMCTRSLTALSEPRTPGPPGLTTTPAP 1080
Query: 1081 PDKLGGKQRAAFKSGKRVGKPSPKAASSPSNPAALPVASDSSPMGSKTKETDSPSTPGKD 1140
PDKLGGKQRAAFKSGKRVGKPSPKAASSPSNPAALPVASDSSPMGSKTKETDSPSTPGKD
Sbjct: 1081 PDKLGGKQRAAFKSGKRVGKPSPKAASSPSNPAALPVASDSSPMGSKTKETDSPSTPGKD 1140
Query: 1141 QRSMILRSRTKTQEIFHSKRRRPSEGRLPNCRATKKLLDNSHLPATFKVSSSPQKEGRVS 1200
QRSMILRSRTKTQEIFHSKRRRPSEGRLPNCRATKKLLDNSHLPATFKVSSSPQKEGRVS
Sbjct: 1141 QRSMILRSRTKTQEIFHSKRRRPSEGRLPNCRATKKLLDNSHLPATFKVSSSPQKEGRVS 1200
Query: 1201 QRARVPKPGAGSKLSDRPLHALKRKSAFMAPVPTKKRNLVLRSRSSSSSNASGNGGDGKE 1260
QRARVPKPGAGSKLSDRPLHALKRKSAFMAPVPTKKRNLVLRSRSSSSSNASGNGGDGKE
Sbjct: 1201 QRARVPKPGAGSKLSDRPLHALKRKSAFMAPVPTKKRNLVLRSRSSSSSNASGNGGDGKE 1260
Query: 1261 ERPEGSPTLFKRMSSPKKAKPTKGNGEPATKLPPPETPDACLKLASRAAFQGAMKTKVLP 1320
ERPEGSPTLFKRMSSPKKAKPTKGNGEPATKLPPPETPDACLKLASRAAFQGAMKTKVLP
Sbjct: 1261 ERPEGSPTLFKRMSSPKKAKPTKGNGEPATKLPPPETPDACLKLASRAAFQGAMKTKVLP 1320
Query: 1321 PRKGRGLKLEAIVQKITSPSLKKFACKAPGASPGNPLSPSLSDKDRGLKGAGGSPVGVEE 1380
PRKGRGLKLEAIVQKITSPSLKKFACKAPGASPGNPLSPSLSDKDRGLKGAGGSPVGVEE
Sbjct: 1321 PRKGRGLKLEAIVQKITSPSLKKFACKAPGASPGNPLSPSLSDKDRGLKGAGGSPVGVEE 1380
Query: 1381 GLVNVGTGQKLPTSGADPLCRNPTNRSLKGKLMNSKKLSSTDCFKTEAFTSPEALQPGGT 1440
GLVNVGTGQKLPTSGADPLCRNPTNRSLKGKLMNSKKLSSTDCFKTEAFTSPEALQPGGT
Sbjct: 1381 GLVNVGTGQKLPTSGADPLCRNPTNRSLKGKLMNSKKLSSTDCFKTEAFTSPEALQPGGT 1440
Query: 1441 ALAPKKRSRKGRAGAHGLSKGPLEKRPYLGPALLLTPRDRASGTQGASEDNSGGGGKKPK 1500
ALAPKKRSRKGRAGAHGLSKGPLEKRPYLGPALLLTPRDRASGTQGASEDNSGGGGKKPK
Sbjct: 1441 ALAPKKRSRKGRAGAHGLSKGPLEKRPYLGPALLLTPRDRASGTQGASEDNSGGGGKKPK 1500
Query: 1501 MEELGLASQPPEGRPCQPQTRAQKQPGHTNYSSYSKRKRLTRGRAKNTTSSPCKGRAKRR 1560
MEELGLASQPPEGRPCQPQTRAQKQPGHTNYSSYSKRKRLTRGRAKNTTSSPCKGRAKRR
Sbjct: 1501 MEELGLASQPPEGRPCQPQTRAQKQPGHTNYSSYSKRKRLTRGRAKNTTSSPCKGRAKRR 1560
Query: 1561 RQQQVLPLDPAEPEIRLKYISSCKRLRSDSRTPAFSPFVRVEKRDAFTTICTVVNSPGDA 1620
RQQQVLPLDPAEPEIRLKYISSCKRLRSDSRTPAFSPFVRVEKRDAFTTICTVVNSPGDA
Sbjct: 1561 RQQQVLPLDPAEPEIRLKYISSCKRLRSDSRTPAFSPFVRVEKRDAFTTICTVVNSPGDA 1620
Query: 1621 PKPHRKPSSSASSSSSSSSFSLDAAGASLATLPGGSILQPRPSLPLSSTMHLGPVVSKAL 1680
PKPHRKPSSSASSSSSSSSFSLDAAGASLATLPGGSILQPRPSLPLSSTMHLGPVVSKAL
Sbjct: 1621 PKPHRKPSSSASSSSSSSSFSLDAAGASLATLPGGSILQPRPSLPLSSTMHLGPVVSKAL 1680
Query: 1681 STSCLVCCLCQNPANFKDLGDLCGPYYPEHCLPKKKPKLKEKVRPEGTCEEASLPLERTL 1740
STSCLVCCLCQNPANFKDLGDLCGPYYPEHCLPKKKPKLKEKVRPEGTCEEASLPLERTL
Sbjct: 1681 STSCLVCCLCQNPANFKDLGDLCGPYYPEHCLPKKKPKLKEKVRPEGTCEEASLPLERTL 1740
Query: 1741 KGPECAAAATAGKPPRPDGPADPAKQGPLRTSARGLSRRLQSCYCCDGREDGGEEAAPAD 1800
KGPECAAAATAGKPPRPDGPADPAKQGPLRTSARGLSRRLQSCYCCDGREDGGEEAAPAD
Sbjct: 1741 KGPECAAAATAGKPPRPDGPADPAKQGPLRTSARGLSRRLQSCYCCDGREDGGEEAAPAD 1800
Query: 1801 KGRKHECSKEAPAEPGGEAQEHWVHEACAVWTGGVYLVAGKLFGLQEAMKVAVDMMCSSC 1860
KGRKHECSKEAPAEPGGEAQEHWVHEACAVWTGGVYLVAGKLFGLQEAMKVAVDMMCSSC
Sbjct: 1801 KGRKHECSKEAPAEPGGEAQEHWVHEACAVWTGGVYLVAGKLFGLQEAMKVAVDMMCSSC 1860
Query: 1861 QEAGATIGCCHKGCLHTYHYPCASDAGCIFIEENFSLKCPKHKRLP 1906
QEAGATIGCCHKGCLHTYHYPCASDAGCIFIEENFSLKCPKHKRLP
Sbjct: 1861 QEAGATIGCCHKGCLHTYHYPCASDAGCIFIEENFSLKCPKHKRLP 1906
>gi|31652242 transcription factor 20 isoform 2 [Homo sapiens]
Length = 1938
Score = 249 bits (636), Expect = 2e-65
Identities = 226/801 (28%), Positives = 351/801 (43%), Gaps = 114/801 (14%)
Query: 1158 SKRRRPSEGRLPNCRATKKLLDNSHLPATFKVSSSPQKEGRVSQRARVPKPGAGSKLSDR 1217
S++ P++ P +++K H ++ + Q S R+P G S
Sbjct: 1192 SRQTSPAKSSGPPGMSSQKRYGPPHETDGHGLAEATQSSKPGSVMLRLP--GQEDHSSQN 1249
Query: 1218 PLHALKRKSAFMAPVPTKKRNLVLRSRSSSSSNASGNGGDGKEERPEGSPTLFKRMSSPK 1277
PL +R +F++P+P+K+++ +++ S+ G EG+ F +
Sbjct: 1250 PLIMRRRVRSFISPIPSKRQSQDVKNSSTEDK------GRLLHSSKEGADKAFNSYAHLS 1303
Query: 1278 KAKPTKG--NGEPATKLPPPETPDA-CLKLASRAAFQGAMKTKVLPPRKGRGLKLEAIVQ 1334
++ K + + LP P++ + + L S A KTK+LPPRKGRGLKLEAIVQ
Sbjct: 1304 HSQDIKSIPKRDSSKDLPSPDSRNCPAVTLTSPA------KTKILPPRKGRGLKLEAIVQ 1357
Query: 1335 KITSPSLKKFACKAPGASPGNPLSPSLSDKDRGLKGAGGSPVGVEEGLVNVGTGQKLPTS 1394
KITSP++++ A + G+ ++ D L G P G + + ++
Sbjct: 1358 KITSPNIRRSASSNSAEAGGDTVT-----LDDILSLKSGPPEGGSVAVQDADIEKRKGEV 1412
Query: 1395 GADPLCRNPTNRSLK-----GKLMNSKKLSSTDCFKTE--AFTSPEALQPGG---TALAP 1444
+D + +P N+ L + + S D KTE A T +P G + +
Sbjct: 1413 ASDLV--SPANQELHVEKPLPRSSEEWRGSVDDKVKTETHAETVTAGKEPPGAMTSTTSQ 1470
Query: 1445 KKRSRKGRAGAHGLSKGPL--EKRPYLGPALLLTP------RDRASGTQGASEDNSGGGG 1496
K S +GR PL + P +L P ++ + T S G
Sbjct: 1471 KPGSNQGRPDGSLGGTAPLIFPDSKNVPPVGILAPEANPKAEEKENDTVTISPKQEGFPP 1530
Query: 1497 K------KPKMEELGLAS------QPPEGRPCQPQTRAQKQPGHTNYSSYSKRKRLTRGR 1544
K K K +G + QPP P PQ G + K++R R R
Sbjct: 1531 KGYFPSGKKKGRPIGSVNKQKKQQQPPPPPPQPPQI----PEGSADGEPKPKKQRQRRER 1586
Query: 1545 AKNTTSSPCKGRAKRRRQQQVLPLDPAEPEIRLKYISSCKRLRSDSRTPAFSPFVRVEKR 1604
K P KR+ +Q V ++P EPEI+LKY + ++D++ +F P++ V +
Sbjct: 1587 RK-----PGAQPRKRKTKQAVPIVEPQEPEIKLKYATQ-PLDKTDAKNKSFYPYIHVVNK 1640
Query: 1605 DAFTTICTVVNSPGDAPKPHRKPSSSASSSSSSSSFSLDAAGASLATLPGGSILQPRPSL 1664
+CT++N + + G T P S +L
Sbjct: 1641 CELGAVCTIIN----------------AEEEEQTKLVRGRKGQRSLTPPPSS--TESKAL 1682
Query: 1665 PLSSTMHLGPVVSKALSTSCLVCCLCQNPANFKDLGDLCGPYYPEH---CLPKKKP---- 1717
P SS M GPVV+++ LVCCLC A+++++GDL GP+YP+ LPK P
Sbjct: 1683 PASSFMLQGPVVTESSVMGHLVCCLCGKWASYRNMGDLFGPFYPQDYAATLPKNPPPKRA 1742
Query: 1718 -------KLKEKVRPEGTCEEASLPLERTLKGPECAAAATAGKPPRPDGPADPAKQGPLR 1770
K++ K G+ + E+ + E + A + R D G R
Sbjct: 1743 TEMQSKVKVRHKSASNGSKTDTEEEEEQQQQQKEQRSLAAHPRFKRRHRSEDCG--GGPR 1800
Query: 1771 TSARGLSRRLQSCYCCDGREDGGEE--------AAPADKGRKHECSKEAPAEPGGEAQEH 1822
+ +RGL C +G E + P E + P P ++ E
Sbjct: 1801 SLSRGLP-------CKKAATEGSSEKTVLDSKPSVPTTSEGGPELELQIPELP-LDSNEF 1852
Query: 1823 WVHEACAVWTGGVYLVAGKLFGLQEAMKVAVDMMCSSCQEAGATIGCCHKGCLHTYHYPC 1882
WVHE C +W G+YLV G+L+GLQEA+++A +M CS CQEAGAT+GC +KGC YHYPC
Sbjct: 1853 WVHEGCILWANGIYLVCGRLYGLQEALEIAREMKCSHCQEAGATLGCYNKGCSFRYHYPC 1912
Query: 1883 ASDAGCIFIEENFSLKCPKHK 1903
A DA C+ EENFS++CPKHK
Sbjct: 1913 AIDADCLLHEENFSVRCPKHK 1933
Score = 181 bits (459), Expect = 6e-45
Identities = 197/627 (31%), Positives = 270/627 (43%), Gaps = 91/627 (14%)
Query: 1 MQSFRERCGFHGKQQNYQQTSQETSRLENYRQPSQAGLSCDRQRLLAKDYYNPQPYPSYE 60
MQSFRE+ +HG QQ+Y Q +SRLE + P QA Q S
Sbjct: 1 MQSFREQSSYHGNQQSYPQEVHGSSRLEEF-SPRQA------QMFQNFGGTGGSSGSSGS 53
Query: 61 GGAGTPSGTAAAVAA-------------------DKYHRGSKALP----TQQGLQGRPAF 97
G G G AAA AA D Y+ P T Q Q RP+
Sbjct: 54 GSGGGRRGAAAAAAAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQPPQRRPSG 113
Query: 98 P--GYGVQDSSPYPGRYAGEESLQAWGAPQPPPPQPQPLPAGVAKYDENLMKKTAVPPSR 155
P YG S + +Y E + + A Q L GV+ Y ++ + P S
Sbjct: 114 PVQSYGPPQGSSFGNQYGSEGHVGQFQA------QHSGL-GGVSHYQQDYTGPFS-PGSA 165
Query: 156 QYAEQGA------QVPFRTHSLHVQQPPPPQ---QPLAYPK----LQRQKLQNDIASPLP 202
QY +Q + QV L+ P PQ QP + +QR A+
Sbjct: 166 QYQQQASSQQQQQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQ 225
Query: 203 FPQGTHFPQHSQSFPTSSTYSS--SVQGGGQGAHSYK-SCTAPTAQPHDRPLTASSSLAP 259
G F QH QS +SS+ SS S Q Q SY S ++ S++ A
Sbjct: 226 LRVG-QFGQHYQSSASSSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAY 284
Query: 260 GQRVQNLHAYQSGRLSYDQQQ---QQQQQQQQQQQALQSRHHAQETLHYQNLA-KYQHYG 315
G Q+ ++YQ + +Q Q QQ QQQQQ Q +H +Q + Y N A K
Sbjct: 285 G--TQSNYSYQPQSMKNFEQAKIPQGTQQGQQQQQPQQQQHPSQHVMQYTNAATKLPLQS 342
Query: 316 QQGQGYCQPDAAVRTPEQYYQTFSPSSSHSPARSVGRSPSYSSTPSPLMPNLENFPYSQQ 375
Q GQ Y QP+ VR+P Q++Q FSP S+ SPA SV +SPS SSTPSPLM EN Q
Sbjct: 343 QVGQ-YNQPEVPVRSPMQFHQNFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQ- 400
Query: 376 PLSTGAFPAGITDH-SHFMPLLNPSPTDATSSVDTQAGNCKPLQKDKLPENLLSDLSLQS 434
G+ P G + MP L+P+P+ S ++ A K + +PE L+D L S
Sbjct: 401 ----GSVPMGSRNRILQLMPQLSPTPS-MMPSPNSHAAGFKGFGLEGVPEKRLTDPGLSS 455
Query: 435 LTALTSQVENISNTVQQLLLSKAAVPQKKGVKNLVSRTPEQHKSQHC-SPEGSGYSAEPA 493
L+AL++QV N+ NTVQ +LLS A PQKK K R K+ C + EGS E
Sbjct: 456 LSALSTQVANLPNTVQHMLLSDALTPQKKTSK----RPSSSKKADSCTNSEGSSQPEEQL 511
Query: 494 GTPLSEP-PSSTPQSTHAEPQEADYLSGSEDPLERSF----------LYCNQARGSPARV 542
+P++E S+ + + LSG + ++ A+ P R+
Sbjct: 512 KSPMAESLDGGCSSSSEDQGERVRQLSGQSTSSDTTYKGGASEKAGSSPAQGAQNEPPRL 571
Query: 543 NSNSKAKPESVSTCSVTSPDDMSTKSD 569
N++ A+ E+ S DM SD
Sbjct: 572 NASPAAREEATS----PGAKDMPLSSD 594
Score = 37.4 bits (85), Expect = 0.14
Identities = 45/179 (25%), Positives = 65/179 (36%), Gaps = 14/179 (7%)
Query: 86 PTQQGLQGRPAFPGYGVQDSSPYPGRYAGEESLQA-WGAPQPPPPQPQPLPAGVAKYDEN 144
P Q+G FP G S GR G + Q P PPPPQP +P G A +
Sbjct: 1523 PKQEG------FPPKGYFPSGKKKGRPIGSVNKQKKQQQPPPPPPQPPQIPEGSADGEPK 1576
Query: 145 LMKKTAVPPSRQYAEQGAQVPFRTHSLHVQQPPPPQQPLAYPKLQRQKLQNDIASPLPFP 204
K+ R+ + GAQ P + + PQ+P K Q L A F
Sbjct: 1577 PKKQR---QRRERRKPGAQ-PRKRKTKQAVPIVEPQEPEIKLKYATQPLDKTDAKNKSFY 1632
Query: 205 QGTHFPQHSQSFPTSSTYSSSVQGGG---QGAHSYKSCTAPTAQPHDRPLTASSSLAPG 260
H + + ++ + +G +S T P + + L ASS + G
Sbjct: 1633 PYIHVVNKCELGAVCTIINAEEEEQTKLVRGRKGQRSLTPPPSSTESKALPASSFMLQG 1691
>gi|31652244 transcription factor 20 isoform 1 [Homo sapiens]
Length = 1960
Score = 249 bits (636), Expect = 2e-65
Identities = 226/801 (28%), Positives = 351/801 (43%), Gaps = 114/801 (14%)
Query: 1158 SKRRRPSEGRLPNCRATKKLLDNSHLPATFKVSSSPQKEGRVSQRARVPKPGAGSKLSDR 1217
S++ P++ P +++K H ++ + Q S R+P G S
Sbjct: 1192 SRQTSPAKSSGPPGMSSQKRYGPPHETDGHGLAEATQSSKPGSVMLRLP--GQEDHSSQN 1249
Query: 1218 PLHALKRKSAFMAPVPTKKRNLVLRSRSSSSSNASGNGGDGKEERPEGSPTLFKRMSSPK 1277
PL +R +F++P+P+K+++ +++ S+ G EG+ F +
Sbjct: 1250 PLIMRRRVRSFISPIPSKRQSQDVKNSSTEDK------GRLLHSSKEGADKAFNSYAHLS 1303
Query: 1278 KAKPTKG--NGEPATKLPPPETPDA-CLKLASRAAFQGAMKTKVLPPRKGRGLKLEAIVQ 1334
++ K + + LP P++ + + L S A KTK+LPPRKGRGLKLEAIVQ
Sbjct: 1304 HSQDIKSIPKRDSSKDLPSPDSRNCPAVTLTSPA------KTKILPPRKGRGLKLEAIVQ 1357
Query: 1335 KITSPSLKKFACKAPGASPGNPLSPSLSDKDRGLKGAGGSPVGVEEGLVNVGTGQKLPTS 1394
KITSP++++ A + G+ ++ D L G P G + + ++
Sbjct: 1358 KITSPNIRRSASSNSAEAGGDTVT-----LDDILSLKSGPPEGGSVAVQDADIEKRKGEV 1412
Query: 1395 GADPLCRNPTNRSLK-----GKLMNSKKLSSTDCFKTE--AFTSPEALQPGG---TALAP 1444
+D + +P N+ L + + S D KTE A T +P G + +
Sbjct: 1413 ASDLV--SPANQELHVEKPLPRSSEEWRGSVDDKVKTETHAETVTAGKEPPGAMTSTTSQ 1470
Query: 1445 KKRSRKGRAGAHGLSKGPL--EKRPYLGPALLLTP------RDRASGTQGASEDNSGGGG 1496
K S +GR PL + P +L P ++ + T S G
Sbjct: 1471 KPGSNQGRPDGSLGGTAPLIFPDSKNVPPVGILAPEANPKAEEKENDTVTISPKQEGFPP 1530
Query: 1497 K------KPKMEELGLAS------QPPEGRPCQPQTRAQKQPGHTNYSSYSKRKRLTRGR 1544
K K K +G + QPP P PQ G + K++R R R
Sbjct: 1531 KGYFPSGKKKGRPIGSVNKQKKQQQPPPPPPQPPQI----PEGSADGEPKPKKQRQRRER 1586
Query: 1545 AKNTTSSPCKGRAKRRRQQQVLPLDPAEPEIRLKYISSCKRLRSDSRTPAFSPFVRVEKR 1604
K P KR+ +Q V ++P EPEI+LKY + ++D++ +F P++ V +
Sbjct: 1587 RK-----PGAQPRKRKTKQAVPIVEPQEPEIKLKYATQ-PLDKTDAKNKSFYPYIHVVNK 1640
Query: 1605 DAFTTICTVVNSPGDAPKPHRKPSSSASSSSSSSSFSLDAAGASLATLPGGSILQPRPSL 1664
+CT++N + + G T P S +L
Sbjct: 1641 CELGAVCTIIN----------------AEEEEQTKLVRGRKGQRSLTPPPSS--TESKAL 1682
Query: 1665 PLSSTMHLGPVVSKALSTSCLVCCLCQNPANFKDLGDLCGPYYPEH---CLPKKKP---- 1717
P SS M GPVV+++ LVCCLC A+++++GDL GP+YP+ LPK P
Sbjct: 1683 PASSFMLQGPVVTESSVMGHLVCCLCGKWASYRNMGDLFGPFYPQDYAATLPKNPPPKRA 1742
Query: 1718 -------KLKEKVRPEGTCEEASLPLERTLKGPECAAAATAGKPPRPDGPADPAKQGPLR 1770
K++ K G+ + E+ + E + A + R D G R
Sbjct: 1743 TEMQSKVKVRHKSASNGSKTDTEEEEEQQQQQKEQRSLAAHPRFKRRHRSEDCG--GGPR 1800
Query: 1771 TSARGLSRRLQSCYCCDGREDGGEE--------AAPADKGRKHECSKEAPAEPGGEAQEH 1822
+ +RGL C +G E + P E + P P ++ E
Sbjct: 1801 SLSRGLP-------CKKAATEGSSEKTVLDSKPSVPTTSEGGPELELQIPELP-LDSNEF 1852
Query: 1823 WVHEACAVWTGGVYLVAGKLFGLQEAMKVAVDMMCSSCQEAGATIGCCHKGCLHTYHYPC 1882
WVHE C +W G+YLV G+L+GLQEA+++A +M CS CQEAGAT+GC +KGC YHYPC
Sbjct: 1853 WVHEGCILWANGIYLVCGRLYGLQEALEIAREMKCSHCQEAGATLGCYNKGCSFRYHYPC 1912
Query: 1883 ASDAGCIFIEENFSLKCPKHK 1903
A DA C+ EENFS++CPKHK
Sbjct: 1913 AIDADCLLHEENFSVRCPKHK 1933
Score = 181 bits (459), Expect = 6e-45
Identities = 197/627 (31%), Positives = 270/627 (43%), Gaps = 91/627 (14%)
Query: 1 MQSFRERCGFHGKQQNYQQTSQETSRLENYRQPSQAGLSCDRQRLLAKDYYNPQPYPSYE 60
MQSFRE+ +HG QQ+Y Q +SRLE + P QA Q S
Sbjct: 1 MQSFREQSSYHGNQQSYPQEVHGSSRLEEF-SPRQA------QMFQNFGGTGGSSGSSGS 53
Query: 61 GGAGTPSGTAAAVAA-------------------DKYHRGSKALP----TQQGLQGRPAF 97
G G G AAA AA D Y+ P T Q Q RP+
Sbjct: 54 GSGGGRRGAAAAAAAMASETSGHQGYQGFRKEAGDFYYMAGNKDPVTTGTPQPPQRRPSG 113
Query: 98 P--GYGVQDSSPYPGRYAGEESLQAWGAPQPPPPQPQPLPAGVAKYDENLMKKTAVPPSR 155
P YG S + +Y E + + A Q L GV+ Y ++ + P S
Sbjct: 114 PVQSYGPPQGSSFGNQYGSEGHVGQFQA------QHSGL-GGVSHYQQDYTGPFS-PGSA 165
Query: 156 QYAEQGA------QVPFRTHSLHVQQPPPPQ---QPLAYPK----LQRQKLQNDIASPLP 202
QY +Q + QV L+ P PQ QP + +QR A+
Sbjct: 166 QYQQQASSQQQQQQVQQLRQQLYQSHQPLPQATGQPASSSSHLQPMQRPSTLPSSAAGYQ 225
Query: 203 FPQGTHFPQHSQSFPTSSTYSS--SVQGGGQGAHSYK-SCTAPTAQPHDRPLTASSSLAP 259
G F QH QS +SS+ SS S Q Q SY S ++ S++ A
Sbjct: 226 LRVG-QFGQHYQSSASSSSSSSFPSPQRFSQSGQSYDGSYNVNAGSQYEGHNVGSNAQAY 284
Query: 260 GQRVQNLHAYQSGRLSYDQQQ---QQQQQQQQQQQALQSRHHAQETLHYQNLA-KYQHYG 315
G Q+ ++YQ + +Q Q QQ QQQQQ Q +H +Q + Y N A K
Sbjct: 285 G--TQSNYSYQPQSMKNFEQAKIPQGTQQGQQQQQPQQQQHPSQHVMQYTNAATKLPLQS 342
Query: 316 QQGQGYCQPDAAVRTPEQYYQTFSPSSSHSPARSVGRSPSYSSTPSPLMPNLENFPYSQQ 375
Q GQ Y QP+ VR+P Q++Q FSP S+ SPA SV +SPS SSTPSPLM EN Q
Sbjct: 343 QVGQ-YNQPEVPVRSPMQFHQNFSPISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQ- 400
Query: 376 PLSTGAFPAGITDH-SHFMPLLNPSPTDATSSVDTQAGNCKPLQKDKLPENLLSDLSLQS 434
G+ P G + MP L+P+P+ S ++ A K + +PE L+D L S
Sbjct: 401 ----GSVPMGSRNRILQLMPQLSPTPS-MMPSPNSHAAGFKGFGLEGVPEKRLTDPGLSS 455
Query: 435 LTALTSQVENISNTVQQLLLSKAAVPQKKGVKNLVSRTPEQHKSQHC-SPEGSGYSAEPA 493
L+AL++QV N+ NTVQ +LLS A PQKK K R K+ C + EGS E
Sbjct: 456 LSALSTQVANLPNTVQHMLLSDALTPQKKTSK----RPSSSKKADSCTNSEGSSQPEEQL 511
Query: 494 GTPLSEP-PSSTPQSTHAEPQEADYLSGSEDPLERSF----------LYCNQARGSPARV 542
+P++E S+ + + LSG + ++ A+ P R+
Sbjct: 512 KSPMAESLDGGCSSSSEDQGERVRQLSGQSTSSDTTYKGGASEKAGSSPAQGAQNEPPRL 571
Query: 543 NSNSKAKPESVSTCSVTSPDDMSTKSD 569
N++ A+ E+ S DM SD
Sbjct: 572 NASPAAREEATS----PGAKDMPLSSD 594
Score = 37.4 bits (85), Expect = 0.14
Identities = 45/179 (25%), Positives = 65/179 (36%), Gaps = 14/179 (7%)
Query: 86 PTQQGLQGRPAFPGYGVQDSSPYPGRYAGEESLQA-WGAPQPPPPQPQPLPAGVAKYDEN 144
P Q+G FP G S GR G + Q P PPPPQP +P G A +
Sbjct: 1523 PKQEG------FPPKGYFPSGKKKGRPIGSVNKQKKQQQPPPPPPQPPQIPEGSADGEPK 1576
Query: 145 LMKKTAVPPSRQYAEQGAQVPFRTHSLHVQQPPPPQQPLAYPKLQRQKLQNDIASPLPFP 204
K+ R+ + GAQ P + + PQ+P K Q L A F
Sbjct: 1577 PKKQR---QRRERRKPGAQ-PRKRKTKQAVPIVEPQEPEIKLKYATQPLDKTDAKNKSFY 1632
Query: 205 QGTHFPQHSQSFPTSSTYSSSVQGGG---QGAHSYKSCTAPTAQPHDRPLTASSSLAPG 260
H + + ++ + +G +S T P + + L ASS + G
Sbjct: 1633 PYIHVVNKCELGAVCTIINAEEEEQTKLVRGRKGQRSLTPPPSSTESKALPASSFMLQG 1691
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 75.9 bits (185), Expect = 4e-13
Identities = 277/1331 (20%), Positives = 435/1331 (32%), Gaps = 243/1331 (18%)
Query: 345 SPARSVGRSPSYSSTPSPLMPNLENFPYSQQPLSTGAFPAGITDHSHFMPLLNPSPTDAT 404
+P + G S +Y++T SP + + P+ G +PL+ P+ ++
Sbjct: 659 APTTAKGTS-TYTTTASPFLEGTVSLAPKNHPVKEGTLTT--------LPLV-PTASENC 708
Query: 405 SSVDTQAGNCKPLQKDKLPENLLSDLSLQSLTAL-----TSQVENISNTVQQLLLSKAAV 459
+ C PL L + + SL T +V+ IS+T A
Sbjct: 709 PVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHT-------SALA 761
Query: 460 PQKKGVKNLVSRTPEQHKSQHCSPEGSGYSAEPAG----TPLSEPPSS-----TPQSTHA 510
P V+ +P++ C E SG SA + T L++ PS +PQ+
Sbjct: 762 P--------VASSPKE-----CPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRP 808
Query: 511 EPQEADY--------LSGSEDPLERSFLYCNQ-----ARGSPARVNSNSKAKPESVSTCS 557
++ LS P+E SFL N ++ SPA +S + P+ T S
Sbjct: 809 PTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPS 868
Query: 558 VT---SPDDMSTKSDDSFQSLHGSLPLDSFSKFVAGERDCPRLLLSALAQEDLASEILGL 614
SP ++ ++ +LP + P L +++ + +
Sbjct: 869 AVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPK--------- 919
Query: 615 QEAIGEKADKAWAEAPSLVKDSSKPPFSLENHSACLDSVAKSAWPRPGEPEALPDSLQLD 674
+A A K +PS K + PP + + W P P A P S
Sbjct: 920 -KARATPAPKGIPASPS-PKGAPTPPAATPPSPKGGPATPSPKWA-PTPPAATPPS---P 973
Query: 675 KGGNAKDFSPGLFEDPSVAFATPDPK---KTTGPLSFGTKPTLGVPAPDPTTAAFDCFPD 731
KGG A G P A P PK T P T P + P+P + AA P
Sbjct: 974 KGGPATPSPKGAPTPP--AATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAAT---PF 1028
Query: 732 TTAASSADSANPFAWPEENLGDACPRWGLHPGELTKGLEQGGKASDGISKGDTHEASACL 791
AS+ +A P + P+ T +GG A+ + T A+
Sbjct: 1029 PKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAAT-- 1086
Query: 792 GFQEEDPPGEKVASLPGDFKQEEVGGVKEEAGGLLQCPEVAKADRWLEDSRHCCSTADFG 851
P G P GGL P + + + G
Sbjct: 1087 ---PPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPH-----KGAPTTPAATPPSPKG 1138
Query: 852 DLPLLPPTSRKEDLEAEEEYSSLCELLGSPEQRPGMQDPLSPKAPLI--CTKEEVEEVLD 909
L PP A P + G+ P AP T + L
Sbjct: 1139 GLATPPPKGAPTTPAATP-----------PSPKGGLATPPPKGAPTTPAATPPSPKGGLA 1187
Query: 910 SKAGWGSPCHLSGESVILLGPTVGTESKVQSWFESSLSHMKPGEEGPDGERAPGDSTTSD 969
+ + G+P + + P G + ++ + P +G +P + T+
Sbjct: 1188 TPSPKGAP---TTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTP 1244
Query: 970 ASLAQKPNKPAVPEAPIAKKEPVPRGKSLRSRRVHRGLPEAEDSPCRAPVLPKDLLLPES 1029
A A P+ P P K P P + S + P + +P A V P P+
Sbjct: 1245 A--ATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPS---PKG 1299
Query: 1030 --CTGPPQGQM--------EGAGAPGRGASEGLPRMCTRSLTALSEPRTPGPPGL-TTTP 1078
T PP+G G+PG +G P + A++ P G P L TTP
Sbjct: 1300 GPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAP-----TPPAVTPPSPKGTPTLPATTP 1354
Query: 1079 A-------PPDKLGGKQRAA---FKSGKRVGKPSPKAASS-------PSNPAALPVASDS 1121
+ P K G AA K G + PSPK + P++PA +P++
Sbjct: 1355 SSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKK 1414
Query: 1122 SPMGSKTKE-----------------------------TDSPSTPGKDQRSMILRSRTKT 1152
+P T+E P+TP + +
Sbjct: 1415 APATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPS 1474
Query: 1153 QEIFHSKRRRPSEGRLPNCRATKKLLDNSHLPATFKVSSSPQKEGRVSQRARVPKPGAGS 1212
+ + ++ + AT + LPA + SSP++ R P +
Sbjct: 1475 PKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAV--IPSSPKEVPATPSSRRDPIAPTAT 1532
Query: 1213 KLSDRPLHALKRKSAFMAP---VPTKKRNLVLRSRSSSSSNASGNGGDGKEERPEGSPTL 1269
LS + L K A + P VP+ K+ + + + + S P +P+
Sbjct: 1533 LLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSP---PAVTPST 1589
Query: 1270 FKRMSSPKKAKPTKGNGEPATK---LPPPETPDACLKLASRAAFQGAMKTKVLPPRKGRG 1326
+K SPK+ P+ K PP TP + K + A +G T PP
Sbjct: 1590 YKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKG---TPTSPPVTPSS 1646
Query: 1327 LKLEAIVQKITSPS--LKKFACKAPGASPGNPLSPSLSDKDRGLKGAGGSPVGVEEGLVN 1384
LK TSP+ K P AS G P + L +
Sbjct: 1647 LK-----DSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTR 1701
Query: 1385 VGTGQKLPTSGADPLCRNPTNRSLKGKLMNSKKLSSTDCFKTEAFTSPEALQPGGTALAP 1444
G K ++ + P+C +P+ ++ SK ST +P L P
Sbjct: 1702 KGPQTKKSSATSPPICPDPSAKN------GSKGPLST--------VAPAPLLP---VQKD 1744
Query: 1445 KKRSRKGRAGAHGLSKGPLEKRPYLGPALLLTPRDRASG--TQGASEDNSGGGGKKPKME 1502
++ KG+ +H KGP L P +AS T A E KP+
Sbjct: 1745 SSKTAKGKDASHS-PKGP-----------LAPPESKASTPLTAAAFEKVL----PKPESA 1788
Query: 1503 ELGLASQPPEGRPCQPQTRAQKQPGHTNYSSYSKRKRLTRGRAKNTTSSPCKGRAKRRRQ 1562
+ A PP P P P +++ SP K A +
Sbjct: 1789 SVSAAPSPPVSLPLAPSPVPTLPP----------KQQFLPSSPGLVLESPSKPLAP-ADE 1837
Query: 1563 QQVLPLDPAEP 1573
++LPL P EP
Sbjct: 1838 DELLPLIPPEP 1848
Score = 73.6 bits (179), Expect = 2e-12
Identities = 348/1525 (22%), Positives = 505/1525 (33%), Gaps = 270/1525 (17%)
Query: 337 TFSPSSSHSPARSVGRSPSYSSTPSPLMPNLENFPY-----SQQPLST-GAFPAGITDHS 390
T SPS S + A S SP T S ++ + N Y +Q P+S+ G P +T
Sbjct: 392 TCSPSGSLNVATSFSLSP----TTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVT--- 444
Query: 391 HFMPLLNPSPTDATSSVDTQAGNCKPLQKDKLPENLLSDLSLQSLTALTSQVENISNTVQ 450
NP A + + C P + + S +L + S V
Sbjct: 445 ------NPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVA 498
Query: 451 QLLLSKAA--VPQKKGVKNLVSR------TPEQHKSQHCSPEGSGYSAEPAGTPLSEPPS 502
L + +P + +KNL S T + ++ S EG+ +S AG + P+
Sbjct: 499 TTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPT 558
Query: 503 STPQSTHAEPQEADYLSGS---EDPLERSFLYCNQARGSPARVNSNSKAKPESVSTCSVT 559
P A + S S E PL ++ G P + KP S S+T
Sbjct: 559 VLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIG-----KPAS----SMT 609
Query: 560 SPDDMSTKSDDSFQSLHGSLPLDSFSKFVAGERDCPRLLLSALAQEDLASEILGLQEAIG 619
SP +++ + + DS+ AG LL S+L +A+ L
Sbjct: 610 SPLGVNSSAS--------VIKTDSY----AGPDSAGPLLKSSLITPTVAAFPL------- 650
Query: 620 EKADKAWAEAPSLVKDSSKPPFSLENHSACLDSVAKSAWP-RPGEPEALPDSLQLDKGGN 678
E AD A AP+ K +S + S+A P + G LP
Sbjct: 651 ESADPAGV-APTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLP---------- 699
Query: 679 AKDFSPGLFEDPSVAFATPDPKKTTGPLS-FGTKPTLGVPAPDPTTAAFDCFPDTTAASS 737
P E+ VA P P+ T PL+ P + P P+ P T
Sbjct: 700 ---LVPTASENCPVA---PSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDG 753
Query: 738 ADSANPFAWPEENLGDACPRWGLHPGELTKGLEQGGKASDGISKGDTH---EASACLGF- 793
+ A P + CP E G ++ SKG ++ + LG
Sbjct: 754 ISHTSALA-PVASSPKECPT------------EDSGASATASSKGTLTYLADSPSPLGVS 800
Query: 794 ---QEEDPPGEKVASLPGDFKQEEVGGVKEEAGGLLQCPEVAKADRWLEDSRHCCSTADF 850
Q + PP +K ++ P V L PE + + + +DS +
Sbjct: 801 VSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFL--PENSLSFQGSKDSPATTHSPT- 857
Query: 851 GDLPLLPPTSRKEDLEAEEEYSSLCELLGSPEQRPGMQDPLSPKAPLICTKEE-VEEVLD 909
PP+ + G+P P PLSPK + KE V++
Sbjct: 858 ------PPSPK-----------------GAPT--PSAVTPLSPKGVTLPPKETPTPSVVN 892
Query: 910 SKAGWGSPCHLSGESVILLGPTVGTESKVQSWFESSLSHMKPGEEGPDGERAPGDSTTSD 969
P + + L T + K ++ P +G +P + T
Sbjct: 893 LPFPKEGPATPAPKQAPALSMTSSSPKKARA---------TPAPKGIPASPSPKGAPTPP 943
Query: 970 ASLAQKPNK-PAVPE-----APIAKKEPVPRGKSLRSRRVHRGLPEAEDSPCR----APV 1019
A+ P PA P P A P P+G P A P A
Sbjct: 944 AATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATP 1003
Query: 1020 LPKDLLLPESCTGP-PQGQMEGAGAPGRGASEGLPRMCTRSLTALSEPRTPGPPGLTTTP 1078
PK P + T P P+G P +GAS P T S TP P G TTP
Sbjct: 1004 SPKGAPTPPAVTPPSPKGSPAATPFP-KGAST--PPAATPPSPKGSPAATPLPKGAPTTP 1060
Query: 1079 AP--PDKLGGKQRAAFKSGKR---VGKPSPK---AASSPSNPAALPVASDSSPMG--SKT 1128
A P GG + K PSPK A SP P A+ SP G +
Sbjct: 1061 AATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATP 1120
Query: 1129 KETDSPSTPGKDQRSMILRSRTKTQEIFHSKRRRPSEGRLPNCRATKKLLDNSHLPATFK 1188
+P+TP S T P +G AT P+
Sbjct: 1121 PHKGAPTTPAATPPSPKGGLATP-----------PPKGAPTTPAATP--------PSPKG 1161
Query: 1189 VSSSPQKEGRVSQRARVPKPGAGSKLSDRPLHALKRKSAFMAPVPTKKRNLVLRSRSSSS 1248
++P +G + A P G + P A +A P+ K L S +
Sbjct: 1162 GLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAA---TPPSPKGGLATPSPKGAP 1218
Query: 1249 SNASGNGGDGK----EERPEGSPTLFKRMSSPKKAKPTKGNGEPATKLPPPE---TPDAC 1301
+ + K P+G+PT A P G PAT PPP+ TP A
Sbjct: 1219 TTPAATPPSPKGGLATPSPKGAPTT-------PAATPPSPKGGPAT--PPPKGAPTPPA- 1268
Query: 1302 LKLASRAAFQGAMKTKVLPPRKGRGLKLEAIVQKITSPSLKKFACKAPGASP--GNPLSP 1359
A+ + +G + T PP KG A+V T PS K P SP G P P
Sbjct: 1269 ---ATPPSLKGGLAT---PPHKGA--PNPAVV---TPPSPKG----GPATSPPKGAPTPP 1313
Query: 1360 SLSDKDRGLKGAGGSPVGVEEGLVNVGTGQKLPTSGADPLCRNPTNRSLKGKLMNSKKLS 1419
+ + KG+ G+P T P+ P T S G S K
Sbjct: 1314 AATPPSP--KGSPGTPPPKGAPTPPAVTP---PSPKGTPTLPATTPSSKGGPTTPSSKEG 1368
Query: 1420 STDCFKTEAFTSPEALQPGGTALAPKKRSRKGRAGAHGLSKGPLEKRPYLGPALLLTPRD 1479
T T + A+ P P S KG S + P PA +T
Sbjct: 1369 PTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDP----TSPAVIPLSPKKAPATPVTREG 1424
Query: 1480 RASGTQGASEDNSGGGGKKPKMEELGLASQPPEGRPCQPQTRAQKQ-PGHTNYSSYSKRK 1538
A+ ++G + P + A+ P+G P P ++ P T S K
Sbjct: 1425 AATPSKGDLTPPA----VTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSP----K 1476
Query: 1539 RLTRGRAKNTTSSPCKGRAKRRRQ-----QQVLPLDPAE----PEIRLKYISSCKRLRSD 1589
+ T+SSP K A V+P P E P R I+ L S
Sbjct: 1477 EPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLS- 1535
Query: 1590 SRTPAFSPFVRVEKRDAFTTICTVVNSPGDAPK---PHRKPSSSASSSSSSSSFSLDAAG 1646
+TPA + ++A V SP P P P++ +S +SS ++ +
Sbjct: 1536 KKTPA-----TLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPP-AVTPST 1589
Query: 1647 ASLATLPGGSILQPRPSLPLSSTMHLGPVVS-------------KALSTSCLVC--CLCQ 1691
A P ++ P + P P V+ K TS V L
Sbjct: 1590 YKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKD 1649
Query: 1692 NPANFKDLGDLCGPYYPEHC--LPKKK-PKLKEKVRPEGTCEEASLPLERTLKGPECAAA 1748
+P + + G P+ LP KK P ++V E + T KGP+ +
Sbjct: 1650 SPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKS 1709
Query: 1749 ATAGKPPRPDGPADPAKQGPLRTSA 1773
+ P PD A +GPL T A
Sbjct: 1710 SATSPPICPDPSAKNGSKGPLSTVA 1734
Score = 54.3 bits (129), Expect = 1e-06
Identities = 112/495 (22%), Positives = 166/495 (33%), Gaps = 89/495 (17%)
Query: 951 PGEEGPDGERAPGDSTTSDASLAQKPNKPAVPEAPIAKKEPVPRGKSLRSRRVHRGLPEA 1010
P P G G +T S P PAV P + KEP P K + + + P A
Sbjct: 1447 PATSAPKG----GPATPSSKG---DPTLPAV--TPPSPKEP-PAPKQVATSSSPKKAP-A 1495
Query: 1011 EDSPCRAPVLPKDL-LLPESCTGPPQGQMEGAGAPGRGASEGLPR-------MCTRSLTA 1062
+P AP LP + P+ P + + S+ P + ++T
Sbjct: 1496 TPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTV 1555
Query: 1063 LSEPRTPGPPGLTTTPAPPDKLGGKQRAAFKSGKRVGKPSPKAASSPSNPAALPVASDSS 1122
S +TP P PA P A G PSPK P P + S
Sbjct: 1556 PSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIP------PAVTSPS 1609
Query: 1123 PMGSKTKETDSPSTPGKDQRSMILRSRTKTQEIFHSKRRRPSEGRLPNCRATKKLLDNSH 1182
P + T +P +P K + + + +
Sbjct: 1610 PKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPV--------------------------- 1642
Query: 1183 LPATFKVSSSPQKEGRVSQRARVPKPGAGSKLSDRPLHALKRKSAFMAP-------VPTK 1235
P++ K S + A VP+ G P ALK AP PT+
Sbjct: 1643 TPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPT-ALKEVLVAPAPESTPIITAPTR 1701
Query: 1236 KRNLVLRSRSSS----SSNASGNGGDGKEERPEGSPTLFKRMSSPKKAKPTKGNGEPATK 1291
K +S ++S ++ NG G +P L + S K AK + P
Sbjct: 1702 KGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGP 1761
Query: 1292 LPPPETPDACLKLASRAAFQGAMKTKVLPPRKGRGLKLE---------AIVQKITSPSLK 1342
L PPE+ + A AAF+ KVLP + + A T P +
Sbjct: 1762 LAPPESKASTPLTA--AAFE-----KVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQ 1814
Query: 1343 KFACKAPG---ASPGNPLSPSLSDKDRGLKGAGGSPVG----VEEGLVNVGTGQKLPTSG 1395
+F +PG SP PL+P +D+D L P+ + LVN+ T +
Sbjct: 1815 QFLPSSPGLVLESPSKPLAP--ADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPV 1872
Query: 1396 ADPLCRNPTNRSLKG 1410
P + P ++ KG
Sbjct: 1873 PTPSAKQPVTKNNKG 1887
Score = 40.8 bits (94), Expect = 0.013
Identities = 54/230 (23%), Positives = 74/230 (32%), Gaps = 31/230 (13%)
Query: 52 NPQPYPSYEGGAGTPS---GTAAAVAADKYHRG------SKALPTQQGLQGRPAFPGYGV 102
+P+ P+ + GA + GT +A G +K PT++G G G
Sbjct: 766 SPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLS 825
Query: 103 QDSSPYPGRYAGEESLQAWGA---------PQPPPPQPQPLPAGVAKYDENLMKKTAVPP 153
SP + E SL G+ P PP P+ P P+ V K +PP
Sbjct: 826 SPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSP---KGVTLPP 882
Query: 154 SRQYAEQGAQVPFRTHSLHVQQPPPPQQPLAYPKLQRQKLQNDIASPLPFPQGTHFPQHS 213
+PF ++ P P P L A P P+G
Sbjct: 883 KETPTPSVVNLPF------PKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSP 936
Query: 214 QSFPTSSTYSSSVQGGGQGAHSYKSCTAPTA----QPHDRPLTASSSLAP 259
+ PT + GG S K P A P P T S AP
Sbjct: 937 KGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAP 986
Score = 40.0 bits (92), Expect = 0.022
Identities = 50/197 (25%), Positives = 69/197 (35%), Gaps = 18/197 (9%)
Query: 57 PSYEGGAGTPSGTAAAV---AADKYHRGSKALPTQQGLQGRPAFPGYGVQDSSPYPGRYA 113
PS +GG TPS A A +G A P+ +G PA ++P P
Sbjct: 948 PSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPA--------ATP-PSPKG 998
Query: 114 GEESLQAWGAPQPP---PPQPQPLPAGVAKYDENLMKKTAVPPSRQYAEQGAQVPFRTHS 170
G + GAP PP PP P+ PA A PPS + + +P +
Sbjct: 999 GPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPT 1058
Query: 171 LHVQQPPPPQQPLAYPKLQRQKLQNDIASPLPFPQGTHFPQHSQSFPTSSTYSSSVQGGG 230
P P+ A P L + A+ P P+G + P + GG
Sbjct: 1059 TPAATLPSPKGGPATPSL--KGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGG 1116
Query: 231 QGAHSYKSC-TAPTAQP 246
+K T P A P
Sbjct: 1117 LATPPHKGAPTTPAATP 1133
Score = 39.7 bits (91), Expect = 0.028
Identities = 51/208 (24%), Positives = 68/208 (32%), Gaps = 26/208 (12%)
Query: 57 PSYEGGAGTPSGTAAAV---AADKYHRGSKALPTQQGLQGRPAFPGYGVQDSSPYPGRYA 113
PS +GG TPS A A +G A P+ +G PA ++P P
Sbjct: 1203 PSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPA--------ATP-PSPKG 1253
Query: 114 GEESLQAWGAPQPPPPQPQPLPAGVAKYDENLMKKTAVPPSRQYAEQGAQVPFRTHSLHV 173
G + GAP PP P L G+ A PP + P
Sbjct: 1254 GPATPPPKGAPTPPAATPPSLKGGL-----------ATPPHKGAPNPAVVTPPSPKGGPA 1302
Query: 174 QQPP--PPQQPLAYPKLQRQKLQNDIASPLPFPQGTHFPQHSQSFPTSSTYSSSVQGGGQ 231
PP P P A P + P P P + PT + S +GG
Sbjct: 1303 TSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAV-TPPSPKGTPTLPATTPSSKGGPT 1361
Query: 232 GAHSYKSCTAPTAQPHDRPLTASSSLAP 259
S + T P A P + A + +P
Sbjct: 1362 TPSSKEGPTPPAATPSHKGGPAMTPPSP 1389
Score = 38.5 bits (88), Expect = 0.063
Identities = 50/202 (24%), Positives = 70/202 (34%), Gaps = 11/202 (5%)
Query: 53 PQPYPSYEGGAGTPSGTAAAVAADKYHRGSKA-----LPTQQGLQGRPAFPGYGVQDSSP 107
P P + A TP + AA +G+ LP+ +G P+ G ++
Sbjct: 1027 PFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAAT 1086
Query: 108 YPGRYAGEESLQAWGAPQPPPPQPQPLPAGVAKYDENLMKKT--AVPPSRQYAEQGAQVP 165
P G + GAP PP P G+A T A PPS + P
Sbjct: 1087 PPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPK-GGLATPPP 1145
Query: 166 FRTHSLHVQQPPPPQQPLAYPKLQRQKLQNDIASPLPFPQGTHFPQHSQSFPTSSTYSSS 225
+ PP P+ LA P + A+P P P+G + PT+ +
Sbjct: 1146 KGAPTTPAATPPSPKGGLATPP-PKGAPTTPAATP-PSPKGGLATPSPKGAPTTPAATPP 1203
Query: 226 VQGGGQGAHSYKSC-TAPTAQP 246
GG S K T P A P
Sbjct: 1204 SPKGGLATPSPKGAPTTPAATP 1225
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 72.8 bits (177), Expect = 3e-12
Identities = 34/90 (37%), Positives = 47/90 (52%), Gaps = 4/90 (4%)
Query: 1814 EPGGEAQEHWVHEACAVWTGGVYLVAG-KLFGLQEAMKVAVDMMCSSCQEAGATIGCCHK 1872
EPGG W H CA W+ GV+ G +L G+ +A+ + CS C GA+I C
Sbjct: 131 EPGGSC---WAHHWCAAWSAGVWGQEGPELCGVDKAIFSGISQRCSHCTRLGASIPCRSP 187
Query: 1873 GCLHTYHYPCASDAGCIFIEENFSLKCPKH 1902
GC YH+PCA+ +G + L CP+H
Sbjct: 188 GCPRLYHFPCATASGSFLSMKTLQLLCPEH 217
Score = 69.3 bits (168), Expect = 3e-11
Identities = 59/222 (26%), Positives = 86/222 (38%), Gaps = 27/222 (12%)
Query: 1705 PYYPEHCLPKKKPKLKEKVRPEGTCEEAS-LPLERTLKGPECAAAATAGKPPRPDGPADP 1763
P P P +P ++ P S LPL + PE A +PP + P
Sbjct: 4920 PLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASS---PESARPKPRARPPEEGEDSRP 4976
Query: 1764 AKQGPLRTSARGLSRRLQSCYCCDGREDGGEEAA---------------PADKGRKHECS 1808
+ + R L + GR++ E A P D R C
Sbjct: 4977 PRLKKWKGVRWKRLRLLLTIQKGSGRQEDEREVAEFMEQLGTALRPDKVPRDMRRCCFCH 5036
Query: 1809 KEAPAEPGGEAQ------EHWVHEACAVWTGGVYLV-AGKLFGLQEAMKVAVDMMCSSCQ 1861
+E G A+ + WVH CA+W+ VY G L ++ A+ + CS CQ
Sbjct: 5037 EEGDGATDGPARLLNLDLDLWVHLNCALWSTEVYETQGGALMNVEVALHRGLLTKCSLCQ 5096
Query: 1862 EAGATIGCCHKGCLHTYHYPCASDAGCIFIEENFSLKCPKHK 1903
GAT C C + YH+ CA A C+F ++ ++ CP HK
Sbjct: 5097 RTGATSSCNRMRCPNVYHFACAIRAKCMFFKDK-TMLCPMHK 5137
Score = 50.1 bits (118), Expect = 2e-05
Identities = 107/446 (23%), Positives = 153/446 (34%), Gaps = 95/446 (21%)
Query: 5 RERCGFHGKQQNYQQTSQETSRLENYRQPSQAGLSCDRQ-RLLAKDYYNPQPYPSYEGGA 63
+E + +N QQ Q+ + + + + LS + RLL K P +
Sbjct: 3586 KEHTNLMAEYRNKQQQQQQQQQQQQQQHSAVLALSPSQSPRLLTKLPGQLLPGHGLQPPQ 3645
Query: 64 GTPSGTAAAVAADKYHRGSKALPTQQG---------LQGRPAFPGYGVQDSSPYPGRYAG 114
G P G A + + G ALP Q G Q + G + P G + G
Sbjct: 3646 GPPGGQAGGL---RLTPGGMALPGQPGGPFLNTALAQQQQQQHSGGAGSLAGPSGGFFPG 3702
Query: 115 EESLQAWGAP----QPPPPQPQPLPAGVAK----------YDENLMKKTAVPPSRQYAE- 159
+L++ G Q Q Q +A+ ++L+ + A+ +Q
Sbjct: 3703 NLALRSLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPG 3762
Query: 160 -----------QGAQVPFRTHSLHVQQ--PPPPQQPLAY-PKLQRQKLQNDIASPLPFPQ 205
QG P L VQQ P PPQ P Q LQ L PQ
Sbjct: 3763 VQTNQALGPKPQGLMPPSSHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALG-PQ 3821
Query: 206 GTHFPQHSQSFPTSSTYSSSVQGGGQG-----------------------------AHSY 236
G H Q T S SS Q QG +H
Sbjct: 3822 GPH----RQVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQ 3877
Query: 237 KSCTAPTAQPH--DRPLTASSSLAPGQRVQN---LHAYQSGRLSYDQQ------QQQQQQ 285
+S + + QP +P+ + L Q++Q L Q +L QQ QQQQQQ
Sbjct: 3878 QSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQ 3937
Query: 286 QQQQQQALQSRHHAQETLHYQNLAKYQHYGQQGQ----GYCQPDAAVRTPEQYYQTFSPS 341
QQ QQQ Q Q+ L Q + Q + QQ Q G + +P+Q Q
Sbjct: 3938 QQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVAL 3997
Query: 342 SSHSPARSVGRSPSYSSTPSPLMPNL 367
PA+ + + S+P L P L
Sbjct: 3998 GPGMPAKPL----QHFSSPGALGPTL 4019
Score = 39.3 bits (90), Expect = 0.037
Identities = 71/300 (23%), Positives = 98/300 (32%), Gaps = 38/300 (12%)
Query: 1007 LPEAEDSPCRAPVLPKDLLLPESCTGPPQGQMEGAGAPGRGASEGLPRMCTRSLTALSEP 1066
LP E+SP P ES T PP + P + LP S P
Sbjct: 441 LPPPEESPLSPPP-------EESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESP 493
Query: 1067 RTPGPPGLTTTPAPPDKLGGKQRAAFKSGKRVGKPSPKAA---SSPSNPAALPVASDSSP 1123
+P P +P P + S PSP S P + L + SP
Sbjct: 494 LSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESP 553
Query: 1124 MGSKTKETDSPSTPGKDQRSMILRSRTKTQEIFHSKRRRPSEGRLPNCRATKKLLDNSHL 1183
+ +E + P + S + S P E S L
Sbjct: 554 LSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEA--------------SRL 599
Query: 1184 PATFKVS--SSPQKEGRVS---QRARVPKPGAGSKLSDRPLHALKRKSAFMAPVPTKKR- 1237
F+ S S P +E +S + +R+ P S +S P + + M+P P R
Sbjct: 600 FPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPP------EESPMSPPPEVSRL 653
Query: 1238 -NLVLRSRSSSSSNASGNGGDGKEERPEGSPTLFKRMSSPKKAKPTKGNGEPATKLPPPE 1296
L + SR S S EE P P R+S P + PT E + PPPE
Sbjct: 654 SPLPVVSRLSPPPEESPLSPP-PEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPE 712
Score = 39.3 bits (90), Expect = 0.037
Identities = 178/815 (21%), Positives = 258/815 (31%), Gaps = 166/815 (20%)
Query: 361 SPLMPNLENFPYSQQPLSTGAFP-------AGITDHSHFM-PL----LNPSPTDATSSVD 408
SPL P E P S P ++ P + + + H PL L+P P ++ S
Sbjct: 447 SPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPP 506
Query: 409 TQAGNCKPLQKDKL--PENLLSDLSLQSLTALTSQVENISNTVQQLLLSKAAVPQKKGVK 466
++ PL++ L PE +L++ + + +S ++ LS
Sbjct: 507 PESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSP---------- 556
Query: 467 NLVSRTPEQHKSQHCSPEGSGYSAEPAGTPLSEPPSSTPQSTHAEPQEADYLSGSEDPLE 526
P + PE S S P +P+S PP +P S P EA L P E
Sbjct: 557 ------PPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSP---PPEASRLF---PPFE 604
Query: 527 RSFLYCNQARGSPARVNSNSKAKPESVSTCSVTSPDDMSTKSDDSFQSLHGSL----PLD 582
S L SP S PE+ MS ++S S + PL
Sbjct: 605 ESPL-------SPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLP 657
Query: 583 SFSKFVAGERDCPRLLLSALAQEDLASEILGLQEAIGEKADKAWAEAPSLVKDSSKPPFS 642
S+ + P LS +E S D + P +S PP
Sbjct: 658 VVSRLSPPPEESP---LSPPPEESPTSPPPEASRLSPPPEDSPTSPPPE-DSPASPPP-- 711
Query: 643 LENHSACLDSVAKSAWPRPGEPEALPDSLQLDKGGNAKDFSPGLFEDPSVAFATPDPKKT 702
E+ L P P EP+ P S P L P +P P++
Sbjct: 712 -EDSLMSLPLEESPLLPLPEEPQLCPRSE-----------GPHLSPRPEEPHLSPRPEEP 759
Query: 703 -TGPLSFGTKPTLGVPAPDPTTAAFDCFPDTTAASSADSANPFAWPEENLGDACPRWGLH 761
P + +P L +P A P + + +P PEE LH
Sbjct: 760 HLSPQA--EEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSP--QPEE----------LH 805
Query: 762 PGELTKGLEQGGKASDGISKGDTHEASACLGFQEEDPPGEKVASLPGDFKQEEVGGVKEE 821
T+ + CL Q E+ + P + E + E
Sbjct: 806 LSPQTEEPHLSPVPEE-----------PCLSPQPEESHLSPQSEEPCLSPRPEESHLSPE 854
Query: 822 AGGLLQCPEVAKADRWLEDSRHCCSTADFGDLPLLPPTSRKEDLEAEEEYSSLCELLGSP 881
L + P + ++ E+ C + + LPL PP SL LLG P
Sbjct: 855 ---LEKPPLSPRPEKPPEEPGQCPAPEE---LPLFPPPGEP----------SLSPLLGEP 898
Query: 882 EQRPGMQDPLSPKAPLICTKEEVEEVLDSKAGWGSPCHLSGESVILLGPTVGTESKVQSW 941
+ PLSP EE+ P SGE L P + +
Sbjct: 899 ALSEPGEPPLSP------LPEEL------------PLSPSGEPS--LSPQLMPPDPLPPP 938
Query: 942 FESSLSHMKPGEEGPDGER-----APGDSTTSD---ASLAQKPNKPAVPEAPIAKKEPVP 993
++ P P GE A GDS A + + P P PEA EPVP
Sbjct: 939 LSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPP-PEANCTDPEPVP 997
Query: 994 RGKSLRSRRVHRGLPEAEDSPC--RAPVLPKDLLLPESCTGPPQGQMEGAGAPGRGASEG 1051
LP + SP +P+L + L P C+ Q + +P
Sbjct: 998 P----------MILPPSPGSPVGPASPILMEPL--PPQCSPLLQHSLVPQNSP------- 1038
Query: 1052 LPRMCTRSLTALSEPRTPGPPGLTTTPAPP--------DKLGGKQRAAFKSGKRVGKPSP 1103
P C+ LS P P G + +K+ + A + PSP
Sbjct: 1039 -PSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSP 1097
Query: 1104 KAASSPSNPAALPVASDSSPMGSKTKETDSPSTPG 1138
S P+ P D S +G T D PG
Sbjct: 1098 MGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPG 1132
Score = 36.6 bits (83), Expect = 0.24
Identities = 88/399 (22%), Positives = 128/399 (32%), Gaps = 40/399 (10%)
Query: 324 PDAAVRTPEQYYQTFSPSSSHSPARSVGRSPSYSST--PSPLMPNLENFPYSQQPLSTGA 381
P+ + +P SP PA + + S SPL P E P S P S+
Sbjct: 453 PEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESS-- 510
Query: 382 FPAGITDHSHFMPLLNPSPTDATSSVDTQAGNCKPLQKDKLPENLLSDLSLQSLTALTSQ 441
P + S P P+ A + + PL E+ LS + T+ +
Sbjct: 511 -PFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPP-FEESPLSPPPEELPTSPPPE 568
Query: 442 VENISNTVQQLLLSKAAVPQKKGVKNLVSRT-----------PEQHKSQHCSPEGSGYSA 490
+S ++ +S SR P + PE S S
Sbjct: 569 ASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSP 628
Query: 491 EPAGTPLSEPPSSTPQSTHAEPQEADYL---SGSEDPLERSFLY--CNQARGSPARVNSN 545
P +P+S PP +P S E L S P E S L ++ SP S
Sbjct: 629 PPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASR 688
Query: 546 SKAKPESVSTCSVTSPDDMSTKSDDSFQSLHGSLPLDSFSKFVAGERDCPRLLLSALAQE 605
PE T S +DS SLPL+ + P L L Q
Sbjct: 689 LSPPPEDSPTSPPPEDSPASPPPEDSLM----SLPLE----------ESPLLPLPEEPQL 734
Query: 606 DLASEILGLQEAIGEKADKAWAEAPSLVKDSSKPPFSLENHSACLDSVAKSAW--PRPGE 663
SE L E E P L + +P S + CL +V + P+
Sbjct: 735 CPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEG 794
Query: 664 PEALPDSLQLDKGGNAKDFSPGLFEDPSVAFATPDPKKT 702
P P +L ++ P L P +P P+++
Sbjct: 795 PHLSPQPEELHLSPQTEE--PHLSPVPEEPCLSPQPEES 831
Score = 35.0 bits (79), Expect = 0.70
Identities = 45/198 (22%), Positives = 72/198 (36%), Gaps = 19/198 (9%)
Query: 933 GTESKVQSWFESSLSHMKPGEEGPDGERAPGDSTTSDASLAQKPNKPAVPEAPIAKKEPV 992
G +++ +S L+ ++ ++ G + + + A+KP P A V
Sbjct: 4482 GLRAEINGHIDSKLAGLE--------QKLQGTPSNKEDAAARKPLTPKPKRVQKASDRLV 4533
Query: 993 PRGKSLRSR---RVHRGL-----PEAEDSPCRAPVLPKD--LLLPESCTGPPQGQMEGAG 1042
K LR R L E P P + + L P P GQ + G
Sbjct: 4534 SSRKKLRKEDGVRASEALLKQLKQELSLLPLTEPAITANFSLFAPFGSGCPVNGQSQLRG 4593
Query: 1043 APGRGASEGLPRMCTRSLTALSEPRTPGPPGLTTTPAPPDKLGGKQRAAFKSGKRVGKPS 1102
A G GA P ++ LT + P PP + P PP + K + +G+
Sbjct: 4594 AFGSGALPTGPDYYSQLLTKNNLSNPPTPPS-SLPPTPPPSVQQKMVNGVTPSEELGEHP 4652
Query: 1103 PKAASSPSNPAALPVASD 1120
AAS+ + AL S+
Sbjct: 4653 KDAASARDSERALRDTSE 4670
Score = 33.5 bits (75), Expect = 2.0
Identities = 64/301 (21%), Positives = 99/301 (32%), Gaps = 71/301 (23%)
Query: 122 GAPQPPPPQPQPL--------PAGVAKYDENLMKKTA--VP------------PSRQYAE 159
GA PPP P PAG++ + +K A VP P + A+
Sbjct: 2111 GALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQVPAQ 2170
Query: 160 QGAQVPFRTHSLHVQQPPPPQQPLAYPKLQRQKLQNDIASPLPFPQGTHFPQHSQSFPTS 219
+Q PF + +P P P YP P+P T P S
Sbjct: 2171 VPSQDPFGLAPAYPLEPRFPTAPPTYP---------------PYPSPTGAPAQPPMLGAS 2215
Query: 220 STYSSSVQGGGQGAHSYKSCTAPTAQPHDRPLTASSSLAPG-QRVQNLHAYQSGRLSYDQ 278
S G GQ + T P P +P T L P + NL +S + +
Sbjct: 2216 SR-----PGAGQPGEFH---TTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGK 2267
Query: 279 QQQQQQQQQQQQQALQSRHHAQETLHYQNLAKYQHYGQQGQGYCQPDAA--------VRT 330
+ ++ ++ +E L A YG G+ ++ ++T
Sbjct: 2268 ASEPLLSPPPFGESRKALEVKKEELG----ASSPSYGPPNLGFVDSPSSGTHLGGLELKT 2323
Query: 331 PEQYYQTFSPSSSHSPARSVGR-------------SPSYSSTPSPLMPNLENFPYSQQPL 377
P+ + +P +S +S G +PS S P P PY+Q PL
Sbjct: 2324 PDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPL 2383
Query: 378 S 378
+
Sbjct: 2384 T 2384
Score = 32.0 bits (71), Expect = 5.9
Identities = 16/31 (51%), Positives = 18/31 (58%)
Query: 261 QRVQNLHAYQSGRLSYDQQQQQQQQQQQQQQ 291
++ Q H QQQQQQQQQQQQQQ
Sbjct: 3582 RKQQKEHTNLMAEYRNKQQQQQQQQQQQQQQ 3612
>gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [Homo
sapiens]
Length = 3969
Score = 71.2 bits (173), Expect = 9e-12
Identities = 44/161 (27%), Positives = 68/161 (42%), Gaps = 17/161 (10%)
Query: 1755 PRPDGPADPAKQGPLRTSARGLSRRLQSCYCCDGREDGGEEAAPADKGRKHECSK----- 1809
P+P GP +P PL + +S RED E P +C+
Sbjct: 1827 PKPKGPGEPDSPTPLHPPTPPILSTDRS------REDSPELNPPPGIEDNRQCALCLTYG 1880
Query: 1810 EAPAEPGGE----AQEHWVHEACAVWTGGVYLVA-GKLFGLQEAMKVAVDMMCSSCQEAG 1864
+ A G Q W H CA+W+ V+ G L + A+ + C CQ+ G
Sbjct: 1881 DDSANDAGRLLYIGQNEWTHVNCALWSAEVFEDDDGSLKNVHMAVIRGKQLRCEFCQKPG 1940
Query: 1865 ATIGCCHKGCLHTYHYPCASDAGCIFIEENFSLKCPKHKRL 1905
AT+GCC C YH+ C+ C+F+++ + C +H+ L
Sbjct: 1941 ATVGCCLTSCTSNYHFMCSRAKNCVFLDDK-KVYCQRHRDL 1980
Score = 32.7 bits (73), Expect = 3.5
Identities = 31/94 (32%), Positives = 40/94 (42%), Gaps = 10/94 (10%)
Query: 1036 GQMEGAGAPGRGASEGLPRMCTRSLTALSEPRTPGPP---GLTTTPAPPDKLGGKQRAAF 1092
G G G GR G PR + + AL P PGPP G P P + AA
Sbjct: 14 GTTGGGGGGGRRGLGGAPR---QRVPALLLP--PGPPVGGGGPGAPPSPPAVAAAAAAAG 68
Query: 1093 KSGKRVGKPSPKAASSPSNPAALPVASDSSPMGS 1126
SG G P AA+S ++ ++ +S SS S
Sbjct: 69 SSG--AGVPGGAAAASAASSSSASSSSSSSSSAS 100
>gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo
sapiens]
Length = 4911
Score = 69.7 bits (169), Expect = 3e-11
Identities = 38/116 (32%), Positives = 58/116 (50%), Gaps = 8/116 (6%)
Query: 1795 EAAPADKGRKHECSKEAPAEPGGEAQ------EHWVHEACAVWTGGVYLV-AGKLFGLQE 1847
+ P D + C +E G A+ + WVH CA+W+ VY AG L ++
Sbjct: 4393 DPVPKDYRKCCFCHEEGDGLTDGPARLLNLDLDLWVHLNCALWSTEVYETQAGALINVEL 4452
Query: 1848 AMKVAVDMMCSSCQEAGATIGCCHKGCLHTYHYPCASDAGCIFIEENFSLKCPKHK 1903
A++ + M C C + GAT GC C + YH+ CA A C+F ++ ++ CP HK
Sbjct: 4453 ALRRGLQMKCVFCHKTGATSGCHRFRCTNIYHFTCAIKAQCMFFKDK-TMLCPMHK 4507
Score = 62.8 bits (151), Expect = 3e-09
Identities = 29/81 (35%), Positives = 40/81 (49%), Gaps = 1/81 (1%)
Query: 1823 WVHEACAVWTGGVYLVAGKLF-GLQEAMKVAVDMMCSSCQEAGATIGCCHKGCLHTYHYP 1881
W H C W+ GV + L + +A+ C+ C+ GATI CC + C YHYP
Sbjct: 250 WAHHRCVEWSLGVCQMEEPLLVNVDKAVVSGSTERCAFCKHLGATIKCCEEKCTQMYHYP 309
Query: 1882 CASDAGCIFIEENFSLKCPKH 1902
CA+ AG + L CP+H
Sbjct: 310 CAAGAGTFQDFSHIFLLCPEH 330
Score = 43.1 bits (100), Expect = 0.003
Identities = 75/316 (23%), Positives = 113/316 (35%), Gaps = 42/316 (13%)
Query: 885 PGMQDPLSPKAPLICTKEEVEEVLD---------SKAGW---GSPCHLSGESVILLGPTV 932
P M P P P ++ V+ S GW +P HL + P
Sbjct: 3297 PTMSQPTFPMVPQQLQHQQHTTVISGHTSPVRMPSLPGWQPNSAPAHLPLNPPRIQPPIA 3356
Query: 933 GTESKVQSWFESSLSHMKPGEEGPDGERAPGDSTTSDASLAQKPNKPAVPEAP----IAK 988
K + ++S+ P + GP D+ S ++ K + E I
Sbjct: 3357 QLPIKTCTPAPGTVSNANP-QSGPPPRVEFDDNNPFSESFQERERKERLREQQERQRIQL 3415
Query: 989 KEPVPRGKSLRSRRV--HRGLPEAEDSPCRAPV---------LPKDLLLPESCTGP---- 1033
+ V R ++L+ R G+ +E S R V LP D + P GP
Sbjct: 3416 MQEVDRQRALQQRMEMEQHGMVGSEISSSRTSVSQIPFYSSDLPCDFMQP---LGPLQQS 3472
Query: 1034 PQGQME-GAGAPGRGASEG-LPRMCTRSLTALSEPRTPGPPGLTTTP-----APPDKLGG 1086
PQ Q + G + +G + T++ +E R GPP P+
Sbjct: 3473 PQHQQQMGQVLQQQNIQQGSINSPSTQTFMQTNERRQVGPPSFVPDSPSIPVGSPNFSSV 3532
Query: 1087 KQRAAFKSGKRVGKPSPKAASSPSNPAALPVASDSSPMGSKTKETDSPSTPGKDQRSMIL 1146
KQ SG + + + +P+ PAA PVA+ S P G + T S PG Q + L
Sbjct: 3533 KQGHGNLSGTSFQQSPVRPSFTPALPAAPPVANSSLPCGQDSTITHGHSYPGSTQSLIQL 3592
Query: 1147 RSRTKTQEIFHSKRRR 1162
S +E KR R
Sbjct: 3593 YSDIIPEEKGKKKRTR 3608
Score = 35.4 bits (80), Expect = 0.54
Identities = 47/217 (21%), Positives = 78/217 (35%), Gaps = 44/217 (20%)
Query: 4 FRERCGFHGKQQNYQQTSQETSRLENYRQPSQAGLSCDRQRLLAKDYYNPQPYPSYEGGA 63
FR++ KQQ + +Q+ +++N +Q Q Q LL + G+
Sbjct: 1753 FRQQMRQKSKQQAKIEATQKLEQVKNEQQQQQQQ-QFGSQHLLV------------QSGS 1799
Query: 64 GTPSGTAAAVAADKYHRGSKALPTQQGLQGRPAFPGYGVQDSSPYPGRYAGEESLQAWGA 123
TPS + + G+ + PA + + P S +
Sbjct: 1800 DTPSSGIQSPLTPQPGNGNMS----------PAQSFHKELFTKQPPSTPTSTSSDDVFVK 1849
Query: 124 PQPPPPQPQPLPAGVAKYDENLMKKTAVPPSRQYAEQGAQVPFRTHSLHVQQPPPPQQPL 183
PQ PP P P P+ + D +T+ PPS Q G+ +PP P P
Sbjct: 1850 PQAPP--PPPAPSRIPIQDSLSQAQTSQPPSPQVFSPGSS---------NSRPPSPMDP- 1897
Query: 184 AYPKLQRQKLQNDIASPLPFPQGTHFPQHSQSFPTSS 220
Y K+ + +P P P G F + + + P +
Sbjct: 1898 -YAKM--------VGTPRPPPVGHSFSRRNSAAPVEN 1925
Score = 33.9 bits (76), Expect = 1.6
Identities = 129/609 (21%), Positives = 205/609 (33%), Gaps = 124/609 (20%)
Query: 636 SSKPPFSLENHSACLDSVAKSAWPRPGEPEALPDSLQLDKGGNAKDFSPGLFEDPSVAFA 695
+ +PP + + S+ V A P P P +P L + ++ SP +F S
Sbjct: 1831 TKQPPSTPTSTSSDDVFVKPQAPPPPPAPSRIPIQDSLSQAQTSQPPSPQVFSPGSSNSR 1890
Query: 696 TPDPKKTTGPLSFGTKPTLGVPAPDPTTAAF----------DCFP-----------DTTA 734
P P + +G P P P +F +C P +TTA
Sbjct: 1891 PPSPMDPYAKM-------VGTPRPPPVGHSFSRRNSAAPVENCTPLSSVSRPLQMNETTA 1943
Query: 735 ----------ASSADSANPFAWPEEN----LGDACPR-WGLHPGELTKGLEQGGKASDGI 779
+SS + +P+A P + + D P+ GL + G + G
Sbjct: 1944 NRPSPVRDLCSSSTTNNDPYAKPPDTPRPVMTDQFPKSLGLSRSPVVSEQTAKGPIAAGT 2003
Query: 780 SKGDTHEASACLGFQEEDPPGEKVASL---------PGDFK---------QEEVGGVKEE 821
S T + FQ + P L PG FK Q+ G V +
Sbjct: 2004 SDHFTKPSPRADVFQRQRIPDSYARPLLTPAPLDSGPGPFKTPMQPPPSSQDPYGSVSQA 2063
Query: 822 AGGLLQCP--EVAKADRWLEDSRHCCSTADFGDLPLLP-PTSRKEDLEAEEEYSSLCELL 878
+ L P A R +++ H S + PL P P + +S +
Sbjct: 2064 SRRLSVDPYERPALTPRPIDNFSHNQSNDPYSQPPLTPHPAVNESFAHPSRAFSQPGTIS 2123
Query: 879 GSPEQRPGMQDPLSPKAPLICTKEEVEEVLDSKA-------GWGSPCHLSGESVILLGPT 931
Q P Q P +P+ P++ + + S G P + S P
Sbjct: 2124 RPTSQDPYSQPPGTPR-PVVDSYSQSSGTARSNTDPYSQPPGTPRPTTVDPYSQQPQTPR 2182
Query: 932 VGTESKVQSWFESSLSHMKPGEEGPDGERAPGDSTTSDASLAQKPNKPAVPEAPIAKKEP 991
T++ + ++ H P P G PG S PA P I+ E
Sbjct: 2183 PSTQTDLFVTPVTNQRHSDPYAH-PPGTPRPGISVPYS-------QPPATPRPRIS--EG 2232
Query: 992 VPRGKSLRSRRVHRGLPEAEDSPCRAPVLPKDLLL-PESCTGPPQGQMEGAGAPGRGASE 1050
R R + P + + R P LP L+ P++C+ P+ PG G S+
Sbjct: 2233 FTRSSMTRPVLMPNQDPFLQAAQNRGPALPGPLVRPPDTCSQTPR-------PPGPGLSD 2285
Query: 1051 GLPRMCTRSLTALSEPRTPGPPGLTTTPAPPDKLGGKQRAAFKSGKRVGKPSPKAASSPS 1110
R+ S +A +P P T + D G Q A +P P + S
Sbjct: 2286 TFSRV---SPSAARDPYDQSP---MTPRSQSDSFGTSQTA----HDVADQPRPGSEGS-- 2333
Query: 1111 NPAALPVASDSSPMGSKTKE----------------TDSPSTPGKDQR-SMILRSRTKTQ 1153
AS +SPM S+ ++ TD+ +T Q + LR R K +
Sbjct: 2334 -----FCASSNSPMHSQGQQFSGVSQLPGPVPTSGVTDTQNTVNMAQADTEKLRQRQKLR 2388
Query: 1154 EIFHSKRRR 1162
EI ++++
Sbjct: 2389 EIILQQQQQ 2397
Score = 33.9 bits (76), Expect = 1.6
Identities = 75/356 (21%), Positives = 119/356 (33%), Gaps = 75/356 (21%)
Query: 991 PVPRGKSLRSRRVHRGLPEAEDSPCRAPVLP-KDLLLPESCTGPPQGQMEGAGAPGRGAS 1049
P +GK R+R+ R +AE + +AP P D+ P P G E P
Sbjct: 3598 PEEKGKKKRTRKKKRD-DDAEST--KAPSTPHSDITAP-----PTPGISETTSTPAVSTP 3649
Query: 1050 EGLPRMCTRSLTALSEPRTPG-----------------------PPGLTTTPAPPDKLGG 1086
LP+ + P TP P T + DKL
Sbjct: 3650 SELPQQADQESVEPVGPSTPNMAAGQLCTELENKLPNSDFSQATPNQQTYANSEVDKLSM 3709
Query: 1087 KQRAAFKSGKRV--------GKPSPK-----AASSPSNPAALPVASDSSPMGSKTKETDS 1133
+ A + K G+ PK + N A PV+S SP S +
Sbjct: 3710 ETPAKTEEIKLEKAETESCPGQEEPKLEEQNGSKVEGNAVACPVSSAQSPPHS----AGA 3765
Query: 1134 PSTPGKDQRSMILRSRTKTQEIFHSKRRRPSEGRL---PNCRATKKLLDNSHLPATFKVS 1190
P+ G D + +L+ K ++ ++P EG + +C KL++ + PA +
Sbjct: 3766 PAAKG-DSGNELLKHLLKNKKSSSLLNQKP-EGSICSEDDCTKDNKLVEKQN-PAEGLQT 3822
Query: 1191 SSPQKEGRVSQRARVPKPGAGSKLSDRPLHALKRKSAFMAPVPTKKRNLVLRSRSSSSSN 1250
Q +G ++PK GS+ + +R AP K++
Sbjct: 3823 LGAQMQGGFGCGNQLPKTDGGSETKKQRSKRTQRTGEKAAPRSKKRKK------------ 3870
Query: 1251 ASGNGGDGKEERPEGSPTLFKRMSSPKKAKPTKGNGEPATKLPPPETPDACLKLAS 1306
EE + + + K+ P LPP P AC K+A+
Sbjct: 3871 --------DEEEKQAMYSSTDTFTHLKQQNNLSNPPTPPASLPPTPPPMACQKMAN 3918
Score = 31.6 bits (70), Expect = 7.7
Identities = 42/189 (22%), Positives = 67/189 (35%), Gaps = 21/189 (11%)
Query: 1100 KPSPKAASSPSNPAALPVASDSSPMGSKTKETDSP------------STPGKDQRSMILR 1147
+P P P PA P A+D P G K+ SP T +D+ SM
Sbjct: 13 QPPPPPPEEPGAPAPSPAAADKRPRGRPRKDGASPFQRARKKPRSRGKTAVEDEDSMDGL 72
Query: 1148 SRTKTQEIFHSKRRRPS-----EGRLPNCRATKKLLDNSHLPATFKVSSSPQKEGRVS-Q 1201
T+T+ I ++ + S E + N + L S + S E ++S Q
Sbjct: 73 ETTETETIVETEIKEQSAEEDAEAEVDNSKQLIPTLQRSVSEESANSLVSVGVEAKISEQ 132
Query: 1202 RARVPKPGAGSKLSDRPLHALKRKSAFMAP---VPTKKRNLVLRSRSSSSSNASGNGGDG 1258
G S L L + F+ P P+ K+++ S + +
Sbjct: 133 LCAFCYCGEKSSLGQGDLKQFRITPGFILPWRNQPSNKKDIDDNSNGTYEKMQNSAPRKQ 192
Query: 1259 KEERPEGSP 1267
+ +R E SP
Sbjct: 193 RGQRKERSP 201
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 67.0 bits (162), Expect = 2e-10
Identities = 318/1474 (21%), Positives = 494/1474 (33%), Gaps = 266/1474 (18%)
Query: 320 GYCQPDAAVRTPEQYYQTFSPSSSHSPARSVGRSPSYSSTPSPLMPNLENFPYSQQPLST 379
G QP A RTP + S SSS P + ++PS S S + P+ + T
Sbjct: 800 GSSQPKAKSRTPPRR----SRSSSSPPPKQKSKTPSRQSHSS-------SSPHPKVKSGT 848
Query: 380 GAFPAGITDHSHFMPLLNPSPTDATSSVDTQAGNCKPLQKDKLPENLLSDLSLQSLTALT 439
IT SP SV Q +C D PE S S + +
Sbjct: 849 PPRQGSIT-----------SPQANEQSVTPQRRSCFESSPD--PELKSRTPSRHSCSG-S 894
Query: 440 SQVENISNTVQQLLLSKAAVPQKKGVKNLVSRTPEQHK-SQHCSPEGSGYSAEPAGTPLS 498
S S+T + S+++ PQ K VK ++S H S SP P +
Sbjct: 895 SPPRVKSSTPPRQSPSRSSSPQPK-VKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSV 953
Query: 499 EPPSST-----PQSTHAEPQEADYLSGSEDPLERSFLYCNQARGSPARVNSNSKAKPESV 553
P S+ P+ +H+ D E P +S GS + P
Sbjct: 954 SPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSH------SGSISPYPKVKAQTPPGP 1007
Query: 554 STCSVTSPDDMSTKSDDSFQSLHGSLPLDSFSKFVA--GERDCPRLLLSALAQEDLASEI 611
S SP D QS GSL L + K GE L Q + +
Sbjct: 1008 SLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPD- 1066
Query: 612 LGLQEAIGEKADKAWAEAPSLVKDSSKPPFSLENHSACLDSVAKSAWPRPGEPEALPDSL 671
+ + ++ +E+PSL S P + S+ + S P + S
Sbjct: 1067 -HRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASP 1125
Query: 672 QLDKGGNAKDFSPGLFEDPSVAFATPDPKKTTGPLSFGT---KPTLGVPAPDPTTAAFDC 728
L G + + F+ S ++ T D G T K + +P + TA+
Sbjct: 1126 MLKSGMSPEQ---SRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATAS--- 1179
Query: 729 FPDTTAASSADSANPFAW---PEENLG-----DACPRWGLHPGELTKGLEQGGKASDGIS 780
D +PF PE +L PR G + EQ
Sbjct: 1180 -----PPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQ 1234
Query: 781 KGDTHEASACLGFQEEDPPGEKVASLPGDFKQEEVGGVKEEAGGLLQCPEVAK--ADRWL 838
+ E + E+P G+ ++ L + K+ + PEV + A
Sbjct: 1235 DEELMEVVE----KSEEPAGQILSHLSSELKEMSTSNFESS-------PEVEERPAVSLT 1283
Query: 839 EDSRHCCSTADFGDLPLLPPTSRKEDLEAEEEYSSLCELLGSPEQRPGMQDPLSPK--AP 896
D ++ + ++P + + E + EL SP + PL + P
Sbjct: 1284 LDQSQSQASLEAVEVPSMASSWGGPHFSPEHK-----ELSNSPLRENSFGSPLEFRNSGP 1338
Query: 897 LICTKEEVEEVLDSKAGWGSPCH--LSGESVILLGPTVGTESKVQSWFESSLSHMKPGEE 954
L + G+ S L+G + L + K QS S S E
Sbjct: 1339 L---------GTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSS---SEL 1386
Query: 955 GPDGERAPGDSTTSDASLAQKPNKPAVPEAPIAK----------KEPVPRGKSLRSRRVH 1004
PD G S+ S P AVP P + K+ +PR S RSR
Sbjct: 1387 SPDAVEKAGMSSNQSIS---SPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGS 1443
Query: 1005 R-GLPEAEDSPCRAPVLPKDLLLPESCTGPPQGQMEGAGAPGRGASEGLPRMCTRSLTAL 1063
GL + +P R S +G G + P RG SE C S
Sbjct: 1444 SPGLRDGSGTPSR-----------HSLSGSSPGMKDIPRTPSRGRSE-----CDSSPEPK 1487
Query: 1064 SEPRTPGPPGLTTTPAPPDKLGGK------QRAAFKSG---KRVGKPSPKAASSPSNPAA 1114
+ P+TP P + +P+ P+ L K +R+ +S K V + S +
Sbjct: 1488 ALPQTPRPR--SRSPSSPE-LNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQE 1544
Query: 1115 LPVASDSSPMGSKTKETDSPSTPGKDQRSMILRSRTKTQEIFHSKRR----RPSEGRLPN 1170
L V +SP +++ SP + K + + RSR+ + SK R R G P
Sbjct: 1545 LDVKPSASPQ-ERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPE 1603
Query: 1171 CRATKKLL-------DNSHLPATFKVSSSPQKE-GRVSQRARVPKPGAGSKLSDRPLHAL 1222
+ + D+S P + P++ S + R P P S P H
Sbjct: 1604 VKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPP 1663
Query: 1223 K-----------------------RKSAFMAPVPTKKRNLVLRSRSSSSSNASGNGGDGK 1259
K R+S+ +P T+K L RSRS+SSS + + +
Sbjct: 1664 KSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPR 1723
Query: 1260 EERPEGSPTLFKRMSSPKKAKPTKGNGEPATKLPPPETPDACLKLASRAAFQGAMKTKVL 1319
R SP+ +SSP+ A+ ++ + + P K SR + K + L
Sbjct: 1724 HRR---SPS----VSSPEPAEKSRSSRRRRSASSPR------TKTTSRRGRSPSPKPRGL 1770
Query: 1320 PPRKGRGLKLEAIVQKITSPSLKKFACKAPGASPGNPLSPSLSDKDRGLKGAGG----SP 1375
+ R + +K + + + + S S S S R +G G SP
Sbjct: 1771 QRSRSRSRR-----EKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSP 1825
Query: 1376 VGVEEGLVNVGTGQKLPTSGADPLCRNPTNRSLKGKLMNSKKLSSTDCFKTEAFTSPEAL 1435
R ++R+ + + T ++ + TSP
Sbjct: 1826 ------------------------ARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSP--- 1858
Query: 1436 QPGGTALAPKKRSRKGRAGA---HGLSKGPL----EKRPYLGPALLLTPRDRASGTQGAS 1488
AP KRSR + A S+ PL R P R R S T+ S
Sbjct: 1859 -------APWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRS 1911
Query: 1489 EDNSGGGGKKPKMEELGLASQPP----EGRPCQPQTRAQ---KQPGHTNYSSYSKRKRLT 1541
+ P + PP R P TR + + P T S S+ +T
Sbjct: 1912 RSRA-----SPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVT 1966
Query: 1542 RGRAKNTTSSPCKGRAKRR-----RQQQVLPLDPAEPEIRLKYISSCKRLRSDSRTPAFS 1596
R R+++ TS + R++ R R++ P S R RS SRTP
Sbjct: 1967 RRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTP--- 2023
Query: 1597 PFVRVEKRDAFTTICTVVNSPGDAPKPHRKPSSSASSSSSSSSFSLDAAGASL--ATLPG 1654
P +R R T + S +P R+ S S + ++ SL + ++ + G
Sbjct: 2024 PAIRRRSRSR-TPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASG 2082
Query: 1655 GSILQPRPSLPLSSTMHLG----PVVSKALSTSC 1684
S + R + P ++ H G PV + SC
Sbjct: 2083 SSSDRSRSATPPATRNHSGSRTPPVALNSSRMSC 2116
Score = 52.8 bits (125), Expect = 3e-06
Identities = 165/820 (20%), Positives = 271/820 (33%), Gaps = 109/820 (13%)
Query: 1068 TPGP-PGLTTTPAPPD---KLGGKQRAAFKSGKRVGKPSPKAASSPSNPAALPVASDSSP 1123
TPG P +T T + K + RAAF S + A P P
Sbjct: 111 TPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEPPKP 170
Query: 1124 MGSKTKETDSPSTPGKDQRSMILRSRTKTQEIFHSKRRRPSEGRLPNCRATKKLLDNSHL 1183
+ + S S K ++ + R + E +R R + R+ + H
Sbjct: 171 YSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHR 230
Query: 1184 PATFKVSSSPQKEGRVSQRARVPKP---------GAGSKLSDRPLHALKRKSAFMAPVPT 1234
T K + + R R+ P P A S S + R +A
Sbjct: 231 SPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAA------A 284
Query: 1235 KKRNLVLRSRSSSSSNASGNGGDG----------KEERPEGSPTLFKRMSSPKKAKPTKG 1284
K L RS S ASG G+G +RP T K+ SSP + K
Sbjct: 285 KTHTTALAGRSPSP--ASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDK 342
Query: 1285 NGEPATKLPP--------PETPDACLKLASRAAFQGAMKTKVLPPRKGRGLK--LEAIVQ 1334
+ AT+ P PE P LA R G+ + P + EA
Sbjct: 343 KEKSATRPSPSPERSSTGPEPPAPTPLLAERHG--GSPQPLATTPLSQEPVNPPSEASPT 400
Query: 1335 KITSPSLKKFACKAPGASPGNPLSPSLSDKDRGLKGAGGSPVGVEEGLVNVGTGQKLPTS 1394
+ SP +S +P SP + R + SP + P
Sbjct: 401 RDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESP-------------KPAPAP 447
Query: 1395 GAD-PLCRNPTNRSLK-GKLMNSKKLSSTDCFKTEAFTSPEALQPGGT-ALAPKKRS--- 1448
G+ + +PT+++ G+ K S T + SP + G + + P KR
Sbjct: 448 GSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSR 507
Query: 1449 -------RKGRAGAHGLSKGPLEKRPYLGPALLLTPRDRASGTQGASEDNSGGGG--KKP 1499
R A G S+ P + P R R + +G S G + P
Sbjct: 508 SRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSP 567
Query: 1500 KMEELGLASQPPEGRPCQPQTRAQKQPGHTNYSSYSKRKRLTRGRAKNTTSSPCKGRAKR 1559
+ P + +T A+++ + R R R ++ + +P + R++
Sbjct: 568 ATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRT 627
Query: 1560 RR--QQQVLPLDPAEPEIRLKYISSCKRLRSDSRTPAFSPFVRVEKRDAFTTICTVVNSP 1617
R +++ PA R + + +R RS SRTPA R + + T S
Sbjct: 628 RSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPA-----RRGRSRSRTPARRSGRSR 682
Query: 1618 GDAPKPHRKPSSSASSSSSSSSFSLDAAGASLATLP-----GGSILQPRPSLPLS---ST 1669
P + S S S SL G S + P GS + + S S
Sbjct: 683 SRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSR 742
Query: 1670 MHLGPVVSKALSTSCLVCCLCQNPANFKDLGDLCGPYYPEHCLPKKK------------- 1716
+ P + K+ +S L + K L PK+K
Sbjct: 743 SNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSS 802
Query: 1717 -PKLKEKVRPEGTCEEASLPLERTLKGPECAAAATAGKPPRPDGPADPAKQGPL---RTS 1772
PK K + P + +S P ++ K P + +++ P+ P +QG + + +
Sbjct: 803 QPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKS-GTPPRQGSITSPQAN 861
Query: 1773 ARGLSRRLQSCYCCDGREDGGEEAAPADKGRKHECSKEAP 1812
+ ++ + +SC+ E + + +H CS +P
Sbjct: 862 EQSVTPQRRSCF-----ESSPDPELKSRTPSRHSCSGSSP 896
Score = 48.9 bits (115), Expect = 5e-05
Identities = 162/770 (21%), Positives = 265/770 (34%), Gaps = 115/770 (14%)
Query: 966 TTSDASLAQKPNKPAVPEAPIAKKEPVPRGKSL-RSRRVHRGLPEAEDSPC-----RAPV 1019
TT S ++ P P ++ PV R +S R+ + R + SP R+
Sbjct: 1941 TTRRRSRSRTP--PVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRT 1998
Query: 1020 LPKDLLLPESCTGPPQGQMEGAGAP------GRGASEGLPRMCTRSLTAL-----SEPRT 1068
P S T P + + P R + LPR +RS + L S RT
Sbjct: 1999 SPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRT 2058
Query: 1069 P----GPPGLTTTPAPPDKLGGKQRAAFKSGKRVGKPSPKAASSPSNPAALPVASDSSPM 1124
P G LT +P P + ++ A+ S R +P A + S PVA +SS M
Sbjct: 2059 PRTARGKRSLTRSP-PAIR---RRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRM 2114
Query: 1125 GSKTKETDSPSTPGKDQRSMILR----SRTKT---QEIFHSKRRRPSEGRLPNCRATKKL 1177
++ + SP+ + + +L SRT Q+ S P R+P+ + T
Sbjct: 2115 SCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGP-RIPDHQRTS-- 2171
Query: 1178 LDNSHLPATFKVSSSPQKEGRVSQRARVPKPGAGSKLSDRPLHALKRKSAFMAPVPTKKR 1237
+ +H + ++ + G + G +++S P APVP
Sbjct: 2172 VPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVP-----------APVP---- 2216
Query: 1238 NLVLRSRSSSSSNASGNGGDGKEERPEGSPTLFKRMSSPKKAKPTKGNGEPATKLPPPET 1297
++ R++ ++N + P S S+ A PT A L T
Sbjct: 2217 --LMSLRTAPAANLASR-------IPAASAAAMNLASARTPAIPT------AVNLADSRT 2261
Query: 1298 PDAC--LKLASRAAFQGAMKTKVLPPRKGRGLKLEAIVQKITSPSLKKFACKAPGASPGN 1355
P A + LAS + PR + + T +L + G P
Sbjct: 2262 PAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGAR-TPAALAALSLTGSGTPPTA 2320
Query: 1356 PLSPSLSDKDRGLKGAG--GSPVGVEEGLVNVGTGQKLPTSGADPLCRNPTNRSLKGKLM 1413
PS S + A G VN+ + L +L G +
Sbjct: 2321 ANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANL 2380
Query: 1414 NSKKLSSTDCFKTEAFTSPEALQ----------PGGTAL----APKKRSRKGRAGAHGLS 1459
S ++ + + TSP L P + + AP SR G+A + L
Sbjct: 2381 TSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLL 2440
Query: 1460 KGPLEKRPYLGPALLLTPRDR--------------------ASGTQGASEDNSGGGGKKP 1499
P + +P + + R A+ T A + N P
Sbjct: 2441 P-PAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAP 2499
Query: 1500 KMEELGLASQPPEGRPCQPQTRAQKQPGHTNYSSYSKRKRLTRGRAKNTTSSPCKGRAKR 1559
+ + P QP A QP SS S + + +++SS
Sbjct: 2500 GVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSS 2559
Query: 1560 RRQQQVLPLDPAEPEIRLKYISSC----KRLRSDSRTPAFSPFVRVEKRDAFTTICTVVN 1615
+ L P +PE+ LK + S K + R P +P R + + ++ + +
Sbjct: 2560 SSDSEGSSL-PVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSS 2618
Query: 1616 SPGDAPKPHRKPSSSASSSSSSSSFSLDAAGASLATLPGGSILQPRPSLP 1665
S + SSS+SSSSSSSS S ++ +S + G P+P+ P
Sbjct: 2619 SSSSSSS---SSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASP 2665
Score = 47.0 bits (110), Expect = 2e-04
Identities = 94/425 (22%), Positives = 154/425 (36%), Gaps = 54/425 (12%)
Query: 887 MQDPLSPKAPLICTKEEVEEVLDSKAGWGSPCHLSGESVILLGPTVGTESKVQSWFESSL 946
+ DP +P AP + + AG +P L+ S L G GT ++ SS
Sbjct: 2284 LADPRTPTAPAV-----------NLAGARTPAALAALS--LTGS--GTPPTAANYPSSSR 2328
Query: 947 SHMKPGEEGPDGERAPGDSTTSDASLAQKPNKPAVPEAPI--AKKEPVPRGKSLRSRRVH 1004
+ P G R+ T+ ++A A+ A + A+ P G +L S RV
Sbjct: 2329 TPQAPASANLVGPRSA--HATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVP 2386
Query: 1005 RGLPEAEDSPCRAPVLPKDLLLPESCTGPPQGQMEGAGAPGRGASEGLPRMCTRSLTALS 1064
E P+L + + P Q +M AP + G + A
Sbjct: 2387 LSAYERVSGRTSPPLLDRARSRTPP-SAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQD 2445
Query: 1065 EPRTPGPPGLTTTPAPPDKLGGKQRAAFKSGKR--VGKPSPKAASSPSNPAALPVASDSS 1122
+PR+P P +AF R + + +P A S + A+ + S+
Sbjct: 2446 QPRSPVP------------------SAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSA 2487
Query: 1123 PMGSKTKETDSPSTPGKDQRSMILRSRTKTQEIFHSKRRRPSEGRLPNCRATKKLLDNSH 1182
+ +P P D + T Q+ +P++ R + ++ +S
Sbjct: 2488 GDHNGMLSVPAPGVPHSDVGEP--PASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSS 2545
Query: 1183 LPATFKVSSSPQKEGRVSQRARVP-KPGAGSKLSDRPLHALK---RKSAFMAPVPTKKRN 1238
++ SSS S+ + +P +P K P A K R+ P P K++
Sbjct: 2546 SSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKR 2605
Query: 1239 LVLRSRSSSS------SNASGNGGDGKEERPEGSPTLFKRMSSPKKAKP-TKGNGEPAT- 1290
S SSSS S++S + S + SSP AKP + +PA+
Sbjct: 2606 RSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASP 2665
Query: 1291 KLPPP 1295
K PPP
Sbjct: 2666 KKPPP 2670
Score = 45.1 bits (105), Expect = 7e-04
Identities = 149/744 (20%), Positives = 256/744 (34%), Gaps = 104/744 (13%)
Query: 943 ESSLSHMKPGEEGPDGERAPGDSTTSDASLAQ-----KPNKPAVPEAPIAKKE---PVPR 994
E +PG +P +T +S + K K A +P ++ P P
Sbjct: 305 EGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPP 364
Query: 995 GKSLRSRRVHRGLPE--AEDSPCRAPVLPKDLLLPESCTGPPQGQMEGAGAPGRGASEGL 1052
+ H G P+ A + PV P P PP+ + + +S
Sbjct: 365 APTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPS 424
Query: 1053 PRMCTRSLTALSEPRTPGP---PG----LTTTPAPPDKLGGKQRA----AFKSGKRVGKP 1101
P+ S A S P +P P PG ++++P ++ G+ + + +R+G+
Sbjct: 425 PQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRS 484
Query: 1102 -SPKAASSPSNPAALPVASDSSPMGSKTKETDSPSTPGKDQRSMILRSRTKTQEIFHSKR 1160
SP A + + P S S + RS R R+++ + R
Sbjct: 485 RSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSR 544
Query: 1161 RRPSEGRLPNCRATKKLLDNSHLPATFKVSSS--PQKEGR------VSQRARVPKPGAGS 1212
R ++ R R+ ++ +S PAT S S P + GR +R+R P
Sbjct: 545 SRNTQ-RRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRR 603
Query: 1213 KLSDRPLHALKRKSAFMAPVPTKKRNLV-LRSRSSSSSNASGNGGDGKEERPEGSPTLF- 1270
S P + +S A ++ R+ V RSRS S + SG R S +
Sbjct: 604 SRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTP 663
Query: 1271 KRMSSPKKAKPTKGNGEPATKLPPPETPDACLKLASRAAFQGAMKTKVLPPRKGRGLKLE 1330
R + P + +G ++ P A +G +++ PR+GR +
Sbjct: 664 ARRGRSRSRTPARRSGRSRSRTP---------------ARRGRSRSRT--PRRGRS-RSR 705
Query: 1331 AIVQKITSPSLKKFACKAPGASPGNPLSPSLSDKDRGLKGAGGSPVGVEEGLVNVGTGQK 1390
++V++ S S + P + S +K R T Q+
Sbjct: 706 SLVRRGRSHS------RTPQRRGRSGSSSERKNKSR--------------------TSQR 739
Query: 1391 LPTSGADPLCRNPTNRSLKGKLMNSKKLSSTDCFKTEAFTSPEALQPGGTALAPKKRSRK 1450
S + P + S + + ++S + + S + P + P +RSR
Sbjct: 740 RSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRS 799
Query: 1451 GRAGAHGLSKGPLEKRPYLGPALLLTPRDRASGTQGASEDNSGGGGKKPKMEELGLASQP 1510
G + S+ P P + P + S T +S K K + P
Sbjct: 800 GSSQPKAKSRTP----PRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKS-----GTPP 850
Query: 1511 PEGRPCQPQTRAQK--QPGHTNYSSYSKRKRLTRGRAKNTTSSPCKGRAKRRRQQQVLPL 1568
+G PQ Q + + S + +R ++++ S R K + P
Sbjct: 851 RQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPS 910
Query: 1569 DPAEPEIRLK-YISSCKRLRSDSRTP---------------AFSPFVRVEKRDAFTTICT 1612
+ P+ ++K IS +R S S +P + SP VE R +
Sbjct: 911 RSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHS 970
Query: 1613 VVNSPGDAPKPHRKPSSSASSSSS 1636
+SP KP P S S S S
Sbjct: 971 GSSSPDTKVKPETPPRQSHSGSIS 994
Score = 43.1 bits (100), Expect = 0.003
Identities = 144/684 (21%), Positives = 234/684 (34%), Gaps = 70/684 (10%)
Query: 956 PDGERAPGDSTTSDASLAQKPNKPAVPEAPIAKKEPVPRGKSLRSRRVHRGLPEAEDSPC 1015
P R ++SD S + P PA ++ PV S S + C
Sbjct: 2073 PAIRRRSASGSSSDRSRSATP--PATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRC 2130
Query: 1016 RAPVLPKDLLLPESCTGPPQGQMEGAGA-----PGRGASE----GLPRMCTRS-----LT 1061
R+P +L P + P ++ AG PG + +P +S LT
Sbjct: 2131 RSP----GMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALT 2186
Query: 1062 ALSEPRTPGPPGLTTT---------PAPPDKLGGKQRAAFKSGKRVGKPSPKA-----AS 1107
A+S PP ++ PAP + + A R+ S A A
Sbjct: 2187 AISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASAR 2246
Query: 1108 SPSNPAALPVASDSSPMGSKTKETDSPSTPGKDQRSMILRSRTKTQEIFH-SKRRRPSEG 1166
+P+ P A+ +A +P + SP T + RT T + + R P+
Sbjct: 2247 TPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAAL 2306
Query: 1167 RLPNCRATKKLLDNSHLPATFKVSSSPQKEGRVSQR---ARVPKPGAGSKLSDRPLHALK 1223
+ + ++ P++ + +P V R A P AGS+ + L
Sbjct: 2307 AALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTA-AALAPAS 2365
Query: 1224 RKSAFMAPVPTKKRNLVLRSRSSSSSNASGNGG----DGKEERPEGSPTLFKRMSSPKKA 1279
SA MAP + R S+ SG D R S RM+S +
Sbjct: 2366 LTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAP 2425
Query: 1280 KPTKGNGE-PATKLPPPETPDACLKLASRAAFQG-AMKTKVLPPRKGRGLKLEAIVQKIT 1337
P+ G+ P+ L PP + S + Q + + P + L A+ +
Sbjct: 2426 SPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTS 2485
Query: 1338 SPSLKKFACKAPGASPGNPLSPSLSDKDRGLKGAGGSPVGVEEGLVNVGTGQKLPTSGAD 1397
S P +PG P S D G A ++ +S +
Sbjct: 2486 SAGDHNGMLSVP--APGVPHS------DVGEPPASTGAQQPSALAALQPAKERRSSSSSS 2537
Query: 1398 PLCRNPTNRSLKGKLMNSKKLSSTDCFKTEAFTSPE-ALQ--PGGTALAPKKRSRKGRAG 1454
+ ++ S +S SS+D + PE AL+ P T APK+ R+GR
Sbjct: 2538 SSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTP-APKEAVREGRPP 2596
Query: 1455 AHGLSKGPLEKRPYLGPALLLTPRDRASGTQGASEDNSGGGGKKPKMEELGLASQPPEGR 1514
+K KR + + +S + +S +S +S P +
Sbjct: 2597 EPTPAK---RKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAK 2653
Query: 1515 P---CQPQTRAQKQPGHTNYSSYSKRKRLTRGR-AKNTTSSPCKGRAKRRRQQQVLPLDP 1570
P P+ + K+P S S RK + R +++ + SP + +RR Q P D
Sbjct: 2654 PGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVE---RRRPSPQPSPRDQ 2710
Query: 1571 AEPEIRLKYISSCKRLRSDSRTPA 1594
S + R DSR+P+
Sbjct: 2711 QSSSSER---GSRRGQRGDSRSPS 2731
Score = 41.2 bits (95), Expect = 0.010
Identities = 116/587 (19%), Positives = 201/587 (34%), Gaps = 67/587 (11%)
Query: 1045 GRGASEGLPRMCTRSLTAL---SEPRTPGPPGLTTTPAP---------PDKLGGKQRA-A 1091
GR S R +RS T S RTP G + + P P + + R+ A
Sbjct: 582 GRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPA 641
Query: 1092 FKSGK-RVGKPSPKAASSPSNPAALPVASDSSPMG-SKTKETDSPSTPGKDQRSMILRSR 1149
+SG+ R P+ + S PA + +P S + +P+ G+ + R R
Sbjct: 642 RRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGR 701
Query: 1150 TKTQEIFHSKRRRPSEGRLPNCR------ATKKLLDNSHLPATFKVSSSPQKEGRVSQRA 1203
++++ + RR S R P R + +K + + SS K+ R+S R
Sbjct: 702 SRSRSLV---RRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRR 758
Query: 1204 RVPKPGAGSKLSDRPLHALKRKSAFMAPVPTKKRNLV-LRSRSSSSSNASGNGGDGKEER 1262
SK R +L+R + +P P +K RSRS SS + + + R
Sbjct: 759 SRSLSSPRSKAKSRL--SLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSR 816
Query: 1263 PEGSPTLFKRMSSPKKAKPTKGNGEPATKLPPPETPDACLKLASRAAFQGAMKTKVLPPR 1322
SP PK+ T ++ P P+ A + V P R
Sbjct: 817 SSSSP-------PPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQR 869
Query: 1323 KGRGLKLEAIVQKITSPSLKKFACKAPGASPGNPLSPSLSDKDRGLKGAGGSPVGVEEGL 1382
+ + + P LK S +P S R SP + +
Sbjct: 870 R-------SCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAI 922
Query: 1383 VNVGTGQKLPTSGADPLCRNPTNRSLKGKLMNSKKLSSTDCFKTEAFTSPEALQPGGTA- 1441
++ P + +P+ + + + S + C E+ P G ++
Sbjct: 923 IS-------PRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSP 975
Query: 1442 ------LAPKKRSRKGRAGAHGLSKGPLEKRPYLGPALLLTPRDRA--SGTQGASEDNSG 1493
P ++S G + K P L + P++++ S Q S
Sbjct: 976 DTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSL 1035
Query: 1494 GGGKK----PKMEELGLASQPPEGR-PCQPQTRA-----QKQPGHTNYSSYSKRKRLTRG 1543
G K P G++S +G+ P R+ + + H+ S + + +
Sbjct: 1036 CAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPK 1095
Query: 1544 RAKNTTSSPCKGRAKRRRQQQVLPLDPAEPEIRLKYISSCKRLRSDS 1590
++ +SSP A R +Q A P ++ R +SDS
Sbjct: 1096 GGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDS 1142
Score = 39.7 bits (91), Expect = 0.028
Identities = 81/356 (22%), Positives = 122/356 (34%), Gaps = 51/356 (14%)
Query: 951 PGEEGPDGERAPGDSTTSDASLAQKPNKPAV--PEAP------------IAKKEPVPRGK 996
P + ERAP S+ + +Q PA P +P IA+ PV +
Sbjct: 2414 PSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQ 2473
Query: 997 SLRSRRVHRGLPEAEDS----PCRAPVLP-KDLLLPESCTGPPQGQMEGAGAPG--RGAS 1049
SL S V A D AP +P D+ P + TG Q A P R +S
Sbjct: 2474 SLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSS 2533
Query: 1050 EGLPRMCTRSLTALSEPRTPGPPGLTTTPAPPDKLGGKQRAAFKSGKRVGKPSPKAASS- 1108
+ S ++ S + G +++ + L + A K RV P+P +
Sbjct: 2534 SSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALK---RVPSPTPAPKEAV 2590
Query: 1109 ----PSNPAALPVASDSSPMGSKTKETDSPSTPGKDQRSMILRSRTKTQEIFHSKRRRPS 1164
P P SS S + + S S+ S S + + S PS
Sbjct: 2591 REGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPS 2650
Query: 1165 EGRLPNCRATKKLLDNSHLPATFKVSSSPQKEGRVSQRARVPKPGAGSKLSDRPLHALKR 1224
+ P +A K +SP+K +R+R P+ S R L
Sbjct: 2651 PAK-PGPQALPK-------------PASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPV 2696
Query: 1225 KSAFMAPVPTKKRNLVLRSRSSSSSNASGNGGDG-----KEERPEGSPTLFKRMSS 1275
+ +P P+ + +S SS + G GD K R SP + SS
Sbjct: 2697 ERRRPSPQPSPRDQ---QSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSS 2749
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 65.1 bits (157), Expect = 6e-10
Identities = 31/87 (35%), Positives = 45/87 (51%), Gaps = 2/87 (2%)
Query: 1820 QEHWVHEACAVWTGGVYLVA-GKLFGLQEAMKVAVDMMCSSCQEAGATIGCCHKGCLHTY 1878
Q W H CA+W+ V+ G L + A+ M C C + GAT+GCC CL +
Sbjct: 1603 QNEWTHVNCAIWSAEVFEENDGSLKNVHAAVARGRQMRCELCLKPGATVGCCLSSCLSNF 1662
Query: 1879 HYPCASDAGCIFIEENFSLKCPKHKRL 1905
H+ CA + CIF +++ + C KH L
Sbjct: 1663 HFMCARASYCIF-QDDKKVFCQKHTDL 1688
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 63.9 bits (154), Expect = 1e-09
Identities = 104/414 (25%), Positives = 137/414 (33%), Gaps = 77/414 (18%)
Query: 52 NPQPYPSYEGG--AGTPSGTAAAVAADKYH--RGSKALP--------TQQGLQGRPAFP- 98
+PQ YP GG +G P G AA G K P + G G P
Sbjct: 216 HPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKP 275
Query: 99 -----GYGVQDSSPYPGRYAGEESLQAWGAPQPPPPQP-------------QPLPAGVAK 140
G G S+P P + P PP +P QPLP +
Sbjct: 276 PTTPVGGGNLPSAPPPANFPHVTP----NLPPPPALRPLNNASASPPGLGAQPLPGHLPS 331
Query: 141 YDENLMKKTAVPPSRQYAEQGAQVPFRTHSLHVQQPPPPQQPLAYP--------KLQRQK 192
+PP E+G + HSL P P+ +P
Sbjct: 332 PHAMGQGMGGLPPG---PEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSS 388
Query: 193 LQNDIASPLPFPQGTHFPQHSQSFPTSSTYSSSVQGGGQGAHSYKSCTA-----PTAQPH 247
+ +S PFP P + SFP ++ S S Q S S P P+
Sbjct: 389 SSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPY 448
Query: 248 DRPLTASSSLAPGQ------RVQNLHAYQSGRLSYDQQQQQQQQQQQQQQALQSRHHAQE 301
R L A+S+ PG H S + QQQQQQQQQQQQQQ Q +HH
Sbjct: 449 GR-LLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNS 507
Query: 302 TLHYQNLAKYQHYGQQGQGYCQPDAAVRTPEQYYQTFSPSSSHSPARSVGRSPSYSSTPS 361
+ H + G + A+ + + P +H P SYS
Sbjct: 508 --GPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPH--SQVSYSQA-G 562
Query: 362 PLMPNLENFPYSQQPLSTGAFPAGITDHSHFMPLLNPS---------PTDATSS 406
P P + + S S G++P SH P P PT TSS
Sbjct: 563 PNGPPVSSSSNSSSSTSQGSYPC-----SHPSPSQGPQGAPYPFPPVPTVTTSS 611
Score = 41.6 bits (96), Expect = 0.007
Identities = 138/630 (21%), Positives = 209/630 (33%), Gaps = 82/630 (13%)
Query: 854 PLLPPTSRKEDLEAEEEYSSLCELLGSPEQRPGMQDPLSPKAPLICTKEEVEEVLDSKAG 913
PL PP+ + D + +S E P + P AP+ + + + G
Sbjct: 163 PLFPPSPQPPDSTPRQPEASF-------EPHPSVT-PTGYHAPM---EPPTSRMFQAPPG 211
Query: 914 WGSP---CHLSGESVILLGPTVGTESKVQSWFESSLSHMKPGEEGPDGERAPGDSTTSDA 970
P + G +L GP +G + + SS+ G++ P P ++S A
Sbjct: 212 APPPHPQLYPGGTGGVLSGPPMGPKGGGAA---SSVGGPNGGKQHPP-PTTPISVSSSGA 267
Query: 971 SLAQKPNKPAVPEAPIAKKEPVPRGKSLRSRRVHRGLPEAEDS----PCRAPVLPKDLLL 1026
S A P KP P P+ G +L S P + P P+
Sbjct: 268 SGAP-PTKP--PTTPVG-------GGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASP 317
Query: 1027 PESCTGPPQGQMEGAGAPGRGASEGLPRMCTRSLTALSEPRTPGPPGLTTTPAPPDKL-- 1084
P P G + A G+G GLP + T P + PP ++ PAPP +
Sbjct: 318 PGLGAQPLPGHLPSPHAMGQGMG-GLPPGPEKGPTLAPSPHSL-PPASSSAPAPPMRFPY 375
Query: 1085 ------GGKQRAAFKSGKRVGKPSPKAASSPSNPAALPVASDSSPMGSKTKETDSPSTPG 1138
++ S P P + + PS P + P + S K T PS P
Sbjct: 376 SSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYT-QPSLPS 434
Query: 1139 KDQRSM-----ILRSRTKTQEIFHSKRRRPSEGRLPNCRATKKLLDNSHLPATFKVSSSP 1193
+ S R H PS G + H +
Sbjct: 435 QAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQ 494
Query: 1194 QKEGRVSQ---RARVPKPGA-------GSKLSDRPLHALKRKSAFMAPVPTKKRNLVLRS 1243
Q++ + Q + P PGA GS P +A+ + P P +L
Sbjct: 495 QQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHP-YAMSPSLGSLRPYPPGPAHLPPPH 553
Query: 1244 RSSSSSNASGNGGDGKEERPEGSPTL--FKRMSSPKKAKPTKGNGEPATKLPPPETPDAC 1301
S S A NG S T S P ++ +G P +P T A
Sbjct: 554 SQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSAT 613
Query: 1302 LK--LASRAAFQGAMKTKVLPPRKGRGLKLEAIVQKITSPSLKKFACKAPGASPGNPLSP 1359
L +A+ A+ KT P G ++ SP K A PG PG+P P
Sbjct: 614 LSTVIATVASSPAGYKTASPPGPPPYG-------KRAPSPGAYKTA-TPPGYKPGSP--P 663
Query: 1360 SL-SDKDRGLKGAG--GSPVGVEEGLVNVGTGQKLPTSGAD--PLCRNPTNRSLKGKLMN 1414
S + G +G P + G VG G LP +G P P G ++
Sbjct: 664 SFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPG-PLPPAGPSGLPSLPPPPAAPASGPPLS 722
Query: 1415 SKKLSSTDCFKTEAFTSPEALQPGGTALAP 1444
+ ++ E + +PE+ P + +P
Sbjct: 723 ATQIKQE---PAEEYETPESPVPPARSPSP 749
Score = 38.5 bits (88), Expect = 0.063
Identities = 53/248 (21%), Positives = 85/248 (34%), Gaps = 48/248 (19%)
Query: 44 RLLAKDYYNPQPYPSYEGGAGTPSGTAAAVAADKYHRGSKALPTQQGLQGRPAFPGYGVQ 103
RLLA +P P+P G S V+ +H + QQ Q +
Sbjct: 450 RLLANSNAHPGPFPP---STGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQ--------- 497
Query: 104 DSSPYPGRYAGEESLQAWGAPQPPPPQ--PQPLPAGVAKYDENLMKKTAVPPSRQYAEQG 161
++ Q G PPPP P PL G + + ++ R Y
Sbjct: 498 -----------QQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGP 546
Query: 162 AQVPFRTHSLHVQQPPPPQQPL-------------AYPKLQRQKLQNDIASPLPFPQGTH 208
A +P + Q P P+ +YP Q +P PFP
Sbjct: 547 AHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPP--- 603
Query: 209 FPQHSQSFPTSSTYSSSVQGGGQGAHSYKSCTAPTAQPHDR----PLTASSSLAPGQRVQ 264
P + S T ST ++V G YK+ + P P+ + P ++ PG +
Sbjct: 604 VPTVTTSSATLSTVIATVASSPAG---YKTASPPGPPPYGKRAPSPGAYKTATPPGYKPG 660
Query: 265 NLHAYQSG 272
+ ++++G
Sbjct: 661 SPPSFRTG 668
Score = 33.5 bits (75), Expect = 2.0
Identities = 69/350 (19%), Positives = 120/350 (34%), Gaps = 53/350 (15%)
Query: 55 PYPSYEGGAGTPSGTAAAVAADK--YHRGSKALPTQQGLQGRPAFPGYGVQDSSPYPGRY 112
P P+ + T S A VA+ Y S P G + P G ++ PG
Sbjct: 603 PVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRA----PSPGAYKTATPPGYK 658
Query: 113 AGEESLQAWGAPQPPPPQPQPLPAGVAKYDENLMKKTAVPPSRQYAEQGAQVPFRTHSLH 172
G G P P G K + +PP+ P SL
Sbjct: 659 PGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAG---------PSGLPSL- 708
Query: 173 VQQPPPPQQPLAYPKLQRQKLQNDIASPLPFPQGTHFPQHSQSFP-----TSSTYSSSVQ 227
PPPP P + P L +++ + A P+ P S S P S S S +
Sbjct: 709 ---PPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHASQSAR 765
Query: 228 GGGQGAHSYKSCTAPTAQPHDRPLTASSSLAPGQRVQNLHAYQSGRLSYDQQQQQQQQQQ 287
+ SC + + PL S + + R +Q+ +++++++
Sbjct: 766 FNKHLDRGFNSCA--RSDLYFVPLEGSKLAK-----KRADLVEKVRREAEQRAREEKERE 818
Query: 288 QQQQALQSRHHAQETLHYQNLAKYQHYGQQGQGYCQPDAAVRTPEQYYQTFSPSSSHSPA 347
++++ + R +E + L + Q+G+ + + P + F P S
Sbjct: 819 REREREKEREREKE----RELERSVKLAQEGRAPVECPSLGPVPHR--PPFEPGS----- 867
Query: 348 RSVGRSPSYSSTPSPLMPNLENF--PYSQQPLSTGAFPAGITDHSHFMPL 395
+V P Y +P + L + P+ P G +H ++PL
Sbjct: 868 -AVATVPPYLGPDTPALRTLSEYARPHVMSP--------GNRNHPFYVPL 908
Score = 31.6 bits (70), Expect = 7.7
Identities = 45/182 (24%), Positives = 63/182 (34%), Gaps = 35/182 (19%)
Query: 1617 PGDAPKPHRKPSSS---------ASSSSSSSSFSLDAAGASLATLPGGSILQPRPSLPLS 1667
P P PH + S S +SSS+SSSS S + S + G P P P+
Sbjct: 546 PAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVP 605
Query: 1668 STMHLGPVVSKALSTSCLVCCLCQNPANFKDLGDLCGPYY--------------PEHCLP 1713
+ V + + + S ++ + +PA +K P Y P P
Sbjct: 606 T------VTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKP 659
Query: 1714 KKKPKLKEKVRP--EGTCEEAS----LPLERTLKGPECAAAATAGKPPRPDGPADPAKQG 1767
P + P GT A P T+ A +G P P PA PA
Sbjct: 660 GSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGP 719
Query: 1768 PL 1769
PL
Sbjct: 720 PL 721
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 63.9 bits (154), Expect = 1e-09
Identities = 104/414 (25%), Positives = 137/414 (33%), Gaps = 77/414 (18%)
Query: 52 NPQPYPSYEGG--AGTPSGTAAAVAADKYH--RGSKALP--------TQQGLQGRPAFP- 98
+PQ YP GG +G P G AA G K P + G G P
Sbjct: 216 HPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKP 275
Query: 99 -----GYGVQDSSPYPGRYAGEESLQAWGAPQPPPPQP-------------QPLPAGVAK 140
G G S+P P + P PP +P QPLP +
Sbjct: 276 PTTPVGGGNLPSAPPPANFPHVTP----NLPPPPALRPLNNASASPPGLGAQPLPGHLPS 331
Query: 141 YDENLMKKTAVPPSRQYAEQGAQVPFRTHSLHVQQPPPPQQPLAYP--------KLQRQK 192
+PP E+G + HSL P P+ +P
Sbjct: 332 PHAMGQGMGGLPPG---PEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSS 388
Query: 193 LQNDIASPLPFPQGTHFPQHSQSFPTSSTYSSSVQGGGQGAHSYKSCTA-----PTAQPH 247
+ +S PFP P + SFP ++ S S Q S S P P+
Sbjct: 389 SSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPY 448
Query: 248 DRPLTASSSLAPGQ------RVQNLHAYQSGRLSYDQQQQQQQQQQQQQQALQSRHHAQE 301
R L A+S+ PG H S + QQQQQQQQQQQQQQ Q +HH
Sbjct: 449 GR-LLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNS 507
Query: 302 TLHYQNLAKYQHYGQQGQGYCQPDAAVRTPEQYYQTFSPSSSHSPARSVGRSPSYSSTPS 361
+ H + G + A+ + + P +H P SYS
Sbjct: 508 --GPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPH--SQVSYSQA-G 562
Query: 362 PLMPNLENFPYSQQPLSTGAFPAGITDHSHFMPLLNPS---------PTDATSS 406
P P + + S S G++P SH P P PT TSS
Sbjct: 563 PNGPPVSSSSNSSSSTSQGSYPC-----SHPSPSQGPQGAPYPFPPVPTVTTSS 611
Score = 41.6 bits (96), Expect = 0.007
Identities = 138/630 (21%), Positives = 209/630 (33%), Gaps = 82/630 (13%)
Query: 854 PLLPPTSRKEDLEAEEEYSSLCELLGSPEQRPGMQDPLSPKAPLICTKEEVEEVLDSKAG 913
PL PP+ + D + +S E P + P AP+ + + + G
Sbjct: 163 PLFPPSPQPPDSTPRQPEASF-------EPHPSVT-PTGYHAPM---EPPTSRMFQAPPG 211
Query: 914 WGSP---CHLSGESVILLGPTVGTESKVQSWFESSLSHMKPGEEGPDGERAPGDSTTSDA 970
P + G +L GP +G + + SS+ G++ P P ++S A
Sbjct: 212 APPPHPQLYPGGTGGVLSGPPMGPKGGGAA---SSVGGPNGGKQHPP-PTTPISVSSSGA 267
Query: 971 SLAQKPNKPAVPEAPIAKKEPVPRGKSLRSRRVHRGLPEAEDS----PCRAPVLPKDLLL 1026
S A P KP P P+ G +L S P + P P+
Sbjct: 268 SGAP-PTKP--PTTPVG-------GGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASP 317
Query: 1027 PESCTGPPQGQMEGAGAPGRGASEGLPRMCTRSLTALSEPRTPGPPGLTTTPAPPDKL-- 1084
P P G + A G+G GLP + T P + PP ++ PAPP +
Sbjct: 318 PGLGAQPLPGHLPSPHAMGQGMG-GLPPGPEKGPTLAPSPHSL-PPASSSAPAPPMRFPY 375
Query: 1085 ------GGKQRAAFKSGKRVGKPSPKAASSPSNPAALPVASDSSPMGSKTKETDSPSTPG 1138
++ S P P + + PS P + P + S K T PS P
Sbjct: 376 SSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYT-QPSLPS 434
Query: 1139 KDQRSM-----ILRSRTKTQEIFHSKRRRPSEGRLPNCRATKKLLDNSHLPATFKVSSSP 1193
+ S R H PS G + H +
Sbjct: 435 QAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQ 494
Query: 1194 QKEGRVSQ---RARVPKPGA-------GSKLSDRPLHALKRKSAFMAPVPTKKRNLVLRS 1243
Q++ + Q + P PGA GS P +A+ + P P +L
Sbjct: 495 QQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHP-YAMSPSLGSLRPYPPGPAHLPPPH 553
Query: 1244 RSSSSSNASGNGGDGKEERPEGSPTL--FKRMSSPKKAKPTKGNGEPATKLPPPETPDAC 1301
S S A NG S T S P ++ +G P +P T A
Sbjct: 554 SQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSAT 613
Query: 1302 LK--LASRAAFQGAMKTKVLPPRKGRGLKLEAIVQKITSPSLKKFACKAPGASPGNPLSP 1359
L +A+ A+ KT P G ++ SP K A PG PG+P P
Sbjct: 614 LSTVIATVASSPAGYKTASPPGPPPYG-------KRAPSPGAYKTA-TPPGYKPGSP--P 663
Query: 1360 SL-SDKDRGLKGAG--GSPVGVEEGLVNVGTGQKLPTSGAD--PLCRNPTNRSLKGKLMN 1414
S + G +G P + G VG G LP +G P P G ++
Sbjct: 664 SFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPG-PLPPAGPSGLPSLPPPPAAPASGPPLS 722
Query: 1415 SKKLSSTDCFKTEAFTSPEALQPGGTALAP 1444
+ ++ E + +PE+ P + +P
Sbjct: 723 ATQIKQE---PAEEYETPESPVPPARSPSP 749
Score = 38.5 bits (88), Expect = 0.063
Identities = 53/248 (21%), Positives = 85/248 (34%), Gaps = 48/248 (19%)
Query: 44 RLLAKDYYNPQPYPSYEGGAGTPSGTAAAVAADKYHRGSKALPTQQGLQGRPAFPGYGVQ 103
RLLA +P P+P G S V+ +H + QQ Q +
Sbjct: 450 RLLANSNAHPGPFPP---STGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQ--------- 497
Query: 104 DSSPYPGRYAGEESLQAWGAPQPPPPQ--PQPLPAGVAKYDENLMKKTAVPPSRQYAEQG 161
++ Q G PPPP P PL G + + ++ R Y
Sbjct: 498 -----------QQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGP 546
Query: 162 AQVPFRTHSLHVQQPPPPQQPL-------------AYPKLQRQKLQNDIASPLPFPQGTH 208
A +P + Q P P+ +YP Q +P PFP
Sbjct: 547 AHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPP--- 603
Query: 209 FPQHSQSFPTSSTYSSSVQGGGQGAHSYKSCTAPTAQPHDR----PLTASSSLAPGQRVQ 264
P + S T ST ++V G YK+ + P P+ + P ++ PG +
Sbjct: 604 VPTVTTSSATLSTVIATVASSPAG---YKTASPPGPPPYGKRAPSPGAYKTATPPGYKPG 660
Query: 265 NLHAYQSG 272
+ ++++G
Sbjct: 661 SPPSFRTG 668
Score = 33.5 bits (75), Expect = 2.0
Identities = 69/350 (19%), Positives = 120/350 (34%), Gaps = 53/350 (15%)
Query: 55 PYPSYEGGAGTPSGTAAAVAADK--YHRGSKALPTQQGLQGRPAFPGYGVQDSSPYPGRY 112
P P+ + T S A VA+ Y S P G + P G ++ PG
Sbjct: 603 PVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRA----PSPGAYKTATPPGYK 658
Query: 113 AGEESLQAWGAPQPPPPQPQPLPAGVAKYDENLMKKTAVPPSRQYAEQGAQVPFRTHSLH 172
G G P P G K + +PP+ P SL
Sbjct: 659 PGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAG---------PSGLPSL- 708
Query: 173 VQQPPPPQQPLAYPKLQRQKLQNDIASPLPFPQGTHFPQHSQSFP-----TSSTYSSSVQ 227
PPPP P + P L +++ + A P+ P S S P S S S +
Sbjct: 709 ---PPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHASQSAR 765
Query: 228 GGGQGAHSYKSCTAPTAQPHDRPLTASSSLAPGQRVQNLHAYQSGRLSYDQQQQQQQQQQ 287
+ SC + + PL S + + R +Q+ +++++++
Sbjct: 766 FNKHLDRGFNSCA--RSDLYFVPLEGSKLAK-----KRADLVEKVRREAEQRAREEKERE 818
Query: 288 QQQQALQSRHHAQETLHYQNLAKYQHYGQQGQGYCQPDAAVRTPEQYYQTFSPSSSHSPA 347
++++ + R +E + L + Q+G+ + + P + F P S
Sbjct: 819 REREREKEREREKE----RELERSVKLAQEGRAPVECPSLGPVPHR--PPFEPGS----- 867
Query: 348 RSVGRSPSYSSTPSPLMPNLENF--PYSQQPLSTGAFPAGITDHSHFMPL 395
+V P Y +P + L + P+ P G +H ++PL
Sbjct: 868 -AVATVPPYLGPDTPALRTLSEYARPHVMSP--------GNRNHPFYVPL 908
Score = 31.6 bits (70), Expect = 7.7
Identities = 45/182 (24%), Positives = 63/182 (34%), Gaps = 35/182 (19%)
Query: 1617 PGDAPKPHRKPSSS---------ASSSSSSSSFSLDAAGASLATLPGGSILQPRPSLPLS 1667
P P PH + S S +SSS+SSSS S + S + G P P P+
Sbjct: 546 PAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVP 605
Query: 1668 STMHLGPVVSKALSTSCLVCCLCQNPANFKDLGDLCGPYY--------------PEHCLP 1713
+ V + + + S ++ + +PA +K P Y P P
Sbjct: 606 T------VTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKP 659
Query: 1714 KKKPKLKEKVRP--EGTCEEAS----LPLERTLKGPECAAAATAGKPPRPDGPADPAKQG 1767
P + P GT A P T+ A +G P P PA PA
Sbjct: 660 GSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGP 719
Query: 1768 PL 1769
PL
Sbjct: 720 PL 721
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 62.4 bits (150), Expect = 4e-09
Identities = 139/651 (21%), Positives = 229/651 (35%), Gaps = 95/651 (14%)
Query: 1064 SEPRTPGPPGLTTTPAPPDKLGGKQRAAFKSGKRVGKPSPKAASSPSN------PAALPV 1117
S R+P + +P+P + K + +V +PS + A+S S+ P +P
Sbjct: 196 SHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPE 255
Query: 1118 ASDSSPMGSKTKETDSPSTPGKDQRSMILRSRTKTQEIFHSKRRRPSEGRLPNCRATKKL 1177
+ SP + KE + T + + RSRT+++ H++ RR R
Sbjct: 256 PKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSR---------- 305
Query: 1178 LDNSHLPATFKVSSSPQKEGRVSQRARVPKPGAGSKLSDRPLHALKRKSAFMAPVPTKKR 1237
++ P R S R R P ++ P H R +PV ++R
Sbjct: 306 ------SRSYSPRRRPSPRRRPSPRRRTPP----RRMPPPPRHRRSR-----SPVRRRRR 350
Query: 1238 NLVLRSRSSSSSNASGNGGDGKE-ERPEGSPTLFKRMSSPKKAKPTKGNGEPATKLPPPE 1296
+ S SSSSS++S + K+ + SP R SP + P + + PPP+
Sbjct: 351 SSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPK 410
Query: 1297 TPDACLKLASRAAFQGAMKTKVLPPRKGRGLKLEAIVQKITSPSLKKFACKAPGASPGNP 1356
T + S + + V P R + +K SPS P P
Sbjct: 411 TRHSPTPQQSNRTRKS--RVSVSPGRTSGKVTKHKGTEKRESPS--------PAPKP-RK 459
Query: 1357 LSPSLSDKDRGLKGAGGSPVGV------EEGLVNVGTGQKLPTSGADPLCRNPTNRSLKG 1410
+ S S++D+G K A V + + +G + P + N +
Sbjct: 460 VELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGR 519
Query: 1411 KLMNS-KKLSSTDCFKTEAFTSPEALQPGGTALAPKKRSRKGRAGAHGLSKGPLEKRPYL 1469
+ +S + +S K + TSP + + P +R R + + P +R
Sbjct: 520 RRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRR-----SPSPAPPPRRRRTPT 574
Query: 1470 GPALLLT----PRDRASGTQGASEDNSGGGGKKPKMEELGLASQPPEGRPCQPQTRAQKQ 1525
P T PR R+ + S P + + PP R P +++
Sbjct: 575 PPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRR 634
Query: 1526 PGHT-----NYSSYSKRKRLTRGRAKNTTSSPCKGRAKRRRQQQVLPLDP---------- 1570
H+ S +KR+ + SSP + + R Q P
Sbjct: 635 VSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTS 694
Query: 1571 -----------AEPEIRLKYISSCKRLRSDSRTP-------AFSPFVRVEKRDAFTTICT 1612
+ P+ R S + +R SRTP A SP + +R ++ +
Sbjct: 695 SSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRR--VSSSRS 752
Query: 1613 VVNSPGDAPKPHRKPSSSASSSSSSSSFSLDAAGASLATLPGGSILQPRPS 1663
V SP A K P S S S S+++S A A P S PR S
Sbjct: 753 VSGSPEPAAKKPPAPPSPVQSQSPSTNWS-PAVPVKKAKSPTPSPSPPRNS 802
Score = 51.2 bits (121), Expect = 9e-06
Identities = 83/368 (22%), Positives = 127/368 (34%), Gaps = 45/368 (12%)
Query: 949 MKPGEEGPDGERAPGDSTTSDASLAQKPNKPAVPEAPIAKKEPVPRGKSLRSRRVHRGLP 1008
+ PG + G S A KP K + E+ K + S++ RR +R
Sbjct: 430 VSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQN 489
Query: 1009 EAEDSPCRAPVLPKDLLLPESCTGPPQGQMEGAGAPGRGASEGLPRMCTRSLTALSEPRT 1068
+ S + +D S + +P R AS + + R+
Sbjct: 490 QQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRS 549
Query: 1069 PGPPGL----TTTPAPPDKLGGKQRAAFKSGKRVGKPSPKAASSPSNPAALPVASDSSPM 1124
P PP + +PAPP + ++ +R P P+ S + P+ SP
Sbjct: 550 PSPPPTRRRRSPSPAPPPR--RRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPS 607
Query: 1125 GSKTKETDSPSTPGKDQRSMILRSRTKTQEIFHSKRRRPSEGRLPNCRATKKLLDNSHLP 1184
+ T SP P K + S S + + HS P + P + L + H
Sbjct: 608 PPPKRRTASPPPPPKRRAS---PSPPPKRRVSHSP--PPKQRSSPVTKRRSPSLSSKH-- 660
Query: 1185 ATFKVSSSPQKEGRVSQRARVPKPGAGSKLSDRPLHALKRKSAFMAPVPTKKRNLVLRSR 1244
+ SSP R ++ AR P+P S RP AP + V R
Sbjct: 661 ---RKGSSP---SRSTREARSPQPNKRHSPSPRP----------RAPQTSSSPPPVRRGA 704
Query: 1245 SSSSSNASGNGGDGKEER-----PEGSPTLFKRMSSP--------KKAKPTKGNGEPATK 1291
SSS + R PE P K+ +SP ++ G+ EPA K
Sbjct: 705 SSSPQRRQSPSPSTRPIRRVSRTPE--PKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAK 762
Query: 1292 LPP-PETP 1298
PP P +P
Sbjct: 763 KPPAPPSP 770
Score = 50.8 bits (120), Expect = 1e-05
Identities = 87/370 (23%), Positives = 124/370 (33%), Gaps = 53/370 (14%)
Query: 947 SHMKPGEEGPDGERAPGDSTTSDASLAQKPNKPAVPEAPIAKKEPVPRGKSLRSRRVHRG 1006
SH+K GE G +P S + QK P ++ P R RR
Sbjct: 510 SHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPR------GRRRRSPSPPPTRRRR---- 559
Query: 1007 LPEAEDSPCRAPVLPKDLLLPESCTGPPQGQMEGAGAPGRGASEGLPRMCTRSLTALSEP 1066
SP AP PP+ + P R PR + S S P
Sbjct: 560 ------SPSPAP--------------PPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPP 599
Query: 1067 ----RTPGPPGLTTTPAPPDKLGGKQRAAFKSGKRVG-KPSPKAASSPSNPAALPVASDS 1121
+P PP T +PP + + +RV P PK SSP P S
Sbjct: 600 IQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSK 659
Query: 1122 SPMGSK----TKETDSPSTPGK----DQRSMILRSRTKTQEIFHSKRRRPSEGRLPNCRA 1173
GS T+E SP P K R ++ + + P + P+ +
Sbjct: 660 HRKGSSPSRSTREARSPQ-PNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPS-PS 717
Query: 1174 TKKLLDNSHLPATFKV----SSSPQKEGRVSQRARV---PKPGAGSKLSD-RPLHALKRK 1225
T+ + S P K+ S SPQ RVS V P+P A + P+ +
Sbjct: 718 TRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPS 777
Query: 1226 SAFMAPVPTKKRNLVLRSRSSSSSNASGNGGDGKEERPEGSPTLFKRMSSPKKAKPTKGN 1285
+ + VP KK S S ++ GG K+++ + K+ KK K K
Sbjct: 778 TNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAV 837
Query: 1286 GEPATKLPPP 1295
A P
Sbjct: 838 AAAAAAAVTP 847
Score = 47.4 bits (111), Expect = 1e-04
Identities = 85/356 (23%), Positives = 119/356 (33%), Gaps = 57/356 (16%)
Query: 959 ERAPGDSTTSDASLAQKPNKPAVPEAPIAKKEPVPRGKSLRSRRVHRGLPEAEDSPCRAP 1018
+++ DS +S +S ++P + V + + RR H A SP +
Sbjct: 490 QQSSSDSGSSSSSEDERPKRSHVKNGEVGR------------RRRHSPSRSASPSPRKRQ 537
Query: 1019 VLPKDLLLPESCTGPPQGQMEGAGAPGRGASEGLPRMCTRSLTALSEPRTPGPPGLTTTP 1078
PP + R S P R+ T RTP PP +P
Sbjct: 538 KETSPRGRRRRSPSPPPTRRR------RSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSP 591
Query: 1079 APPDKLGGKQRAAFKSGKRVGKPSPKAASSPSNPAALPVASDSSPMGSKTKETDSPSTPG 1138
+P QR S P PK ++ P AS S P K S S P
Sbjct: 592 SPRRYSPPIQRRYSPS------PPPKRRTASPPPPPKRRASPSPP----PKRRVSHSPPP 641
Query: 1139 KDQRSMILRSRTKTQEIFHSKRRRPS----EGRLPNCRATKKLLDNSHLPATFKVSSSPQ 1194
K + S + + R+ + H K PS E R P K S P + SSSP
Sbjct: 642 KQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQ---PNKRHSPSPRPRAPQTSSSPP 698
Query: 1195 KEGRVS----QRARVPKPGAGSKLSDRPLHALKRKSAFMAPVPTKKRNLVLRS----RSS 1246
R + QR + P P S RP+ + R P P K + S R
Sbjct: 699 PVRRGASSSPQRRQSPSP------STRPIRRVSR-----TPEPKKIKKAASPSPQSVRRV 747
Query: 1247 SSSNASGNGGDGKEERPEGSPTLFKRMSSP---KKAKPTKGNGEPATKLPPPETPD 1299
SSS + + ++P P+ + S A P K P PP D
Sbjct: 748 SSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSD 803
Score = 38.9 bits (89), Expect = 0.048
Identities = 63/283 (22%), Positives = 106/283 (37%), Gaps = 34/283 (12%)
Query: 103 QDSSPYPGRYAGEESLQAWG--APQPPP------PQPQPLPAGVAKYDENLMKKTAVPPS 154
+ +SP P + E S + +P PPP P P P P ++T PP
Sbjct: 527 RSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPP 586
Query: 155 RQYAEQGAQVPFRTHSLHVQQPPPPQQPLAYPKLQRQKLQNDIASPLPFPQG--THFPQH 212
R+ + + + PPP ++ + P +++ ASP P P+ +H P
Sbjct: 587 RRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRR-----ASPSPPPKRRVSHSPPP 641
Query: 213 SQ-SFPT----SSTYSSSVQGGGQGAHSYKSCTAPTAQPHDRPLTASSSLAPGQRVQNLH 267
Q S P S + SS + G + S + +P QP+ R + AP Q
Sbjct: 642 KQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSP--QPNKRHSPSPRPRAP----QTSS 695
Query: 268 AYQSGRLSYDQQQQQQQQQQQQQQALQSRHHAQETLHYQNLAK-----YQHYGQQGQGYC 322
+ R Q++Q + ++ E + A +
Sbjct: 696 SPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSG 755
Query: 323 QPDAAVR---TPEQYYQTFSPSSSHSPARSVGRSPSYSSTPSP 362
P+ A + P Q+ SPS++ SPA V ++ S + +PSP
Sbjct: 756 SPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSP 798
Score = 31.6 bits (70), Expect = 7.7
Identities = 69/320 (21%), Positives = 113/320 (35%), Gaps = 71/320 (22%)
Query: 176 PPPPQQ---PLAYPKLQRQKLQNDIASPLPFPQG-THFPQHSQSFPTSSTYSSSVQGGGQ 231
PPP ++ P P +R++ +P P P+ T P + P+ YS +Q
Sbjct: 552 PPPTRRRRSPSPAPPPRRRR------TPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYS 605
Query: 232 GAHSYKSCTAPTAQPHDRPLTASSSLAPGQRVQNLHAYQSGRLSYDQQQQQQQQQQQQQQ 291
+ K TA P R AS S P +RV + S +Q+ +++
Sbjct: 606 PSPPPKRRTASPPPPPKR--RASPSPPPKRRVSH---------SPPPKQRSSPVTKRRSP 654
Query: 292 ALQSRHHAQETLHYQNLAKYQHYGQQGQGYCQPDAAVRTPEQYYQTFSPSSSHSPARSVG 351
+L S+H ++G + R+P+ P+ HSP+
Sbjct: 655 SLSSKH------------------RKGSSPSRSTREARSPQ-------PNKRHSPSPRP- 688
Query: 352 RSPSYSSTPSPLMPNLENFPYSQQPLSTGAFP----AGITDHSHFMPLLNPSPTDATSSV 407
R+P SS+P P+ + P +Q S P + + +PSP
Sbjct: 689 RAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVS 748
Query: 408 DTQAGNCKPLQKDKLPENLLSDLSLQSLTALTSQVENISNTVQQLLLSKAAVPQKKGVKN 467
+++ + P K P S + QS + S AVP KK
Sbjct: 749 SSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWS----------------PAVPVKKAKSP 792
Query: 468 LVSRTPEQHKSQHCSPEGSG 487
S +P ++ Q EG G
Sbjct: 793 TPSPSPPRNSDQ----EGGG 808
>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
Length = 748
Score = 60.5 bits (145), Expect = 2e-08
Identities = 108/467 (23%), Positives = 154/467 (32%), Gaps = 84/467 (17%)
Query: 89 QGLQGRPAFPGYGVQDSSPYPGR-YAGEESLQAWGAPQPPPPQPQPLPAGVAKYDENLMK 147
Q L G PA G+ PG+ G SL A G P QP P +G+A + ++
Sbjct: 86 QSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQPPPGTSGMAPHSMAVV- 144
Query: 148 KTAVPPSRQYAEQGAQVPFRTHSLHVQQPPPPQQPLAYPKLQRQKLQNDIASPLPFPQGT 207
TA P ++ +Q A QQ QQ A + Q+Q+ Q
Sbjct: 145 STATPQTQLQLQQVA-----LQQQQQQQQFQQQQQAALQQQQQQQQQQQF---------- 189
Query: 208 HFPQHSQSFPTSSTYSSSVQGGGQGAHSYKSCTAPTAQPHDRPLTASSSLAPGQRVQNLH 267
+Q + + VQ Q + H QR+ L
Sbjct: 190 ----QAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQ 245
Query: 268 AYQSGRLSYDQQQQQQQQQQQQQQALQSRHHAQETLHYQNLAKYQHYGQQGQGYCQPDAA 327
Q QQQQQQQQQQQQQQALQ++ Q+ Q QP +
Sbjct: 246 LQQ-------QQQQQQQQQQQQQQALQAQPPIQQPPMQQP---------------QPPPS 283
Query: 328 VRTPEQYYQTFSPSSSHSPARSVGRSPSYSSTPSPLMPNLENFP-------------YSQ 374
P+Q Q + H P + P + PS L P + P Y+Q
Sbjct: 284 QALPQQ-LQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQ 342
Query: 375 QPLSTGAFPAGITDHSHFMPLLNPSPTDATSSVDTQAGNCKPLQKDKLPENLLSDLSLQS 434
PL P + P + P ++V T + P +S SL
Sbjct: 343 PPLKFVRAPMVVQ-----QPPVQPQVQQQQTAVQTAQA-----AQMVAPGVQVSQSSLPM 392
Query: 435 LTALTSQVENISNTVQQLLLSKAAVPQKKGVKNLVSRTPEQHKSQHCSPEGSGYSAEPAG 494
L++ + + Q S PQ S P + S +P S + P+
Sbjct: 393 LSSPSPGQQ------VQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSP 446
Query: 495 TPLSEP-----------PSSTPQSTHAEPQEADYLSGSEDPLERSFL 530
P P PS P +T P +GS E+ +L
Sbjct: 447 QPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQYL 493
Score = 57.4 bits (137), Expect = 1e-07
Identities = 88/372 (23%), Positives = 123/372 (33%), Gaps = 56/372 (15%)
Query: 229 GGQGAHSYKSCTAPTAQPHDRPLTASSSLAPGQRVQNLHAYQSGRLSYDQQQQQQQQQQ- 287
G G + TA P + +L Q+ Q Q L QQQQQQQQ Q
Sbjct: 132 GTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQA 191
Query: 288 -------------QQQQALQSRHHAQE---TLHYQNLAKYQHYGQQGQGYCQPDAAVRTP 331
QQQQ LQ + Q+ LH+QN + Q QQ Q Q +
Sbjct: 192 QQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQ 251
Query: 332 EQYYQTFSPSSSHSPARSVGRSPSYSSTPSP---LMPNLENF---------PYSQQPLST 379
+Q Q + + + P P P L L+ P QQP
Sbjct: 252 QQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVA 311
Query: 380 GAFPAGITDHSHFMPLLNPSPTDATSSVDTQAGNCKPLQKDKLPENLLSDLSLQSLTALT 439
P+ + S PL++ + + TQ PL+ + P + +
Sbjct: 312 QNQPSQLPPQSQTQPLVSQAQALPGQMLYTQ----PPLKFVRAP-------MVVQQPPVQ 360
Query: 440 SQVENISNTVQQLLLSKAAVPQKKGVKNLVSRTPEQHKSQHCSPEGSGYSAEPAGTPLSE 499
QV+ VQ ++ P GV+ S P SP P P
Sbjct: 361 PQVQQQQTAVQTAQAAQMVAP---GVQVSQSSLP-----MLSSPSPGQQVQTPQSMP--P 410
Query: 500 PPSSTPQSTHAEPQEADYLSGSEDPLERSFLYCNQARGSPARVNSNSKAKPESVSTCSVT 559
PP +PQ Q +S P SFL SP+ S S + SV
Sbjct: 411 PPQPSPQPGQPSSQPNSNVSSGPAPSPSSFL------PSPSPQPSQSPVTARTPQNFSVP 464
Query: 560 SPDDMSTKSDDS 571
SP ++T + S
Sbjct: 465 SPGPLNTPVNPS 476
Score = 43.9 bits (102), Expect = 0.002
Identities = 71/290 (24%), Positives = 101/290 (34%), Gaps = 52/290 (17%)
Query: 78 YHRGSKALPTQQGLQGRPAFPGYGVQDSSPYPGRYAGEESLQAWGA-PQPPPPQPQPLPA 136
+H+ + + QQ R A Q + +++LQA QPP QPQP
Sbjct: 224 HHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQP--- 280
Query: 137 GVAKYDENLMKKTAVPPSRQYAEQGAQVPFRTHSLHVQQPPPPQQPLAYPKLQRQKLQND 196
PPS+ +Q Q+ H+ H Q PP PQQP
Sbjct: 281 ---------------PPSQALPQQLQQMH---HTQHHQPPPQPQQP-------------- 308
Query: 197 IASPLPFPQGTHFPQHSQSFPTSSTYSSSVQGGGQGAHSYKSCTAPTAQPHDRPLTASSS 256
P+ Q + P SQ+ P S Q T P + P+
Sbjct: 309 ---PVAQNQPSQLPPQSQTQPLVSQ--------AQALPGQMLYTQPPLKFVRAPMVVQQP 357
Query: 257 LAPGQRVQNLHAYQSGRLSYDQQQQQQQQQQQQQQALQSRHHAQETLHYQNL-AKYQHYG 315
Q Q A Q+ + + Q Q L S Q+ Q++ Q
Sbjct: 358 PVQPQVQQQQTAVQTAQAA-QMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSP 416
Query: 316 QQGQGYCQPDAAVRT-PEQYYQTFSPSSSHSPARS--VGRSPSYSSTPSP 362
Q GQ QP++ V + P +F PS S P++S R+P S PSP
Sbjct: 417 QPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSP 466
Score = 38.9 bits (89), Expect = 0.048
Identities = 58/269 (21%), Positives = 100/269 (37%), Gaps = 45/269 (16%)
Query: 461 QKKGVKNLVSRTPEQHKSQHCSPEGSGYSAEPAGTPLSEPPSSTPQS--THAEPQEADYL 518
Q + + L + +Q + Q + A+P P+ +PP PQ + A PQ+ +
Sbjct: 237 QLQRIAQLQLQQQQQQQQQQQQQQQQALQAQP---PIQQPPMQQPQPPPSQALPQQLQQM 293
Query: 519 SGSEDPLERSFLYCNQARGSPARVNSNSKAKPESVSTCSVTSPDDMSTKSDDSFQSLHGS 578
++ Q + P N S+ P+S + V+ + Q L+
Sbjct: 294 HHTQHHQPPP-----QPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPG------QMLYTQ 342
Query: 579 LPLDSFSKFVAGERDCPRLLLSALAQEDLASEILGLQEAIGEKADKAWAEAPSL-VKDSS 637
PL KFV + Q + ++ Q A+ + A A AP + V SS
Sbjct: 343 PPL----KFVRAPM--------VVQQPPVQPQVQQQQTAV-QTAQAAQMVAPGVQVSQSS 389
Query: 638 KPPFSLENHSACLDSVAK-----SAWPRPGEPEALPDSLQLDKGGNAKDFSPGLFEDPSV 692
P S + + + P+PG+P + P+S + S G PS
Sbjct: 390 LPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNS----------NVSSGPAPSPSS 439
Query: 693 AFATPDPKKTTGPLSFGTKPTLGVPAPDP 721
+P P+ + P++ T VP+P P
Sbjct: 440 FLPSPSPQPSQSPVTARTPQNFSVPSPGP 468
>gi|114431248 hypothetical protein LOC205717 [Homo sapiens]
Length = 2245
Score = 57.8 bits (138), Expect = 1e-07
Identities = 96/415 (23%), Positives = 157/415 (37%), Gaps = 48/415 (11%)
Query: 100 YGVQDSSPYPGRYAGEESLQAWGAPQPPPPQPQPL--PAGVAKYD--ENLMKKTAVPPSR 155
YG Q P +E L + P +PL P+ ++ D + ++ + S
Sbjct: 1282 YGSQPPGPSLMTEYSQEQLNTMTSTIPNSQIQEPLLKPSHESRKDSAKRAVQDDLLLSSA 1341
Query: 156 QYAEQGAQVPFRTHSLHVQQPPPPQQPLAYPKLQRQKLQNDIASPLPFPQGTHFPQHSQS 215
+ + P R S+ + P + Q N S +P H ++
Sbjct: 1342 KRQKHCQPAPLRLESMSLMSRTPDTISDQTQMMVSQIPPNSSNSVVPVSNPAHGDGLTRL 1401
Query: 216 FPTSSTY------SSSVQGGGQGAHSYKSCTAPTAQPHDRPLTASSSLAPGQRVQNLHAY 269
FP S+ + + VQ G Q + + + T A H L A P Q V +LH+
Sbjct: 1402 FPPSNNFVTPALRQTEVQCGSQPSVAEQQQTQ--ASQH---LQALQQHVPAQGVSHLHSN 1456
Query: 270 QSGRLSYDQQQQQQQQQQQQQQA--LQSRHHAQETLHY----QNLAKYQHYGQQGQGYCQ 323
QQQQQQQQQQQQQQA L+ RHH + H+ ++ Q + Q Q
Sbjct: 1457 HLYIKQQQQQQQQQQQQQQQQQAGQLRERHHLYQMQHHVPHAESSVHSQPHNVHQQRTLQ 1516
Query: 324 PDAAVRTPEQYYQTFSPSSSHSPARSVGRSPSYSSTPSPLMPNLENFPYSQQPLSTGAFP 383
+ ++ Q S + G S S T P P+ QQ
Sbjct: 1517 QEVQMQKKRNLVQGTQTSQLSLQPKHHGTDQSRSKTGQP-------HPHHQQMQQ----- 1564
Query: 384 AGITDHSHFMPLLNPSPTDATSSVDTQAGNCKPLQKDKLPENLLSDL----SLQSLTALT 439
HF S T+ + + + N ++ L ++++ S Q + ++
Sbjct: 1565 ---QMQQHF----GSSQTEKSCENPSTSRNHHNHPQNHLNQDIMHQQQDVGSRQQGSGVS 1617
Query: 440 SQVENISNTVQQLLLSKAAVPQKKGVKNLVSRTPEQHKSQHCSPEG---SGYSAE 491
S+ + N +Q+LL S+ Q ++V+R+ + + H PE S YSAE
Sbjct: 1618 SEHVSGHNPMQRLLTSRGLEQQMVSQPSIVTRSSDMTCTPH-RPERNRVSSYSAE 1671
>gi|38787935 BMP-2 inducible kinase isoform a [Homo sapiens]
Length = 1161
Score = 57.8 bits (138), Expect = 1e-07
Identities = 49/159 (30%), Positives = 64/159 (40%), Gaps = 33/159 (20%)
Query: 263 VQNLHAYQSGRLSYDQQQQQQQQQQQQQQALQSRHHAQETLHYQN---LAKYQHYGQQGQ 319
+Q+ H +Q + QQQQQQQQQQQQQQ Q +HH H + +YQH QQ Q
Sbjct: 453 LQHRHPHQQQQQQQQQQQQQQQQQQQQQQQQQQQHHHHHHHHLLQDAYMQQYQHATQQQQ 512
Query: 320 GYCQPDAAVRTPEQYYQTFSPSSSHSPARSVGRSPSYSSTPSPLMPNLENFPYSQ----- 374
Q F S + P S + P+ +MP + + Q
Sbjct: 513 -------------MLQQQFLMHSVYQPQPSASQYPT-------MMPQYQQAFFQQQMLAQ 552
Query: 375 -QPLSTGAFPAGITDHSHFMPLLNPSPTDATSSVDTQAG 412
QP A P +T F P L TSS+ Q G
Sbjct: 553 HQPSQQQASPEYLTSPQEFSPAL----VSYTSSLPAQVG 587
>gi|38787904 BMP-2 inducible kinase isoform b [Homo sapiens]
Length = 662
Score = 57.8 bits (138), Expect = 1e-07
Identities = 49/159 (30%), Positives = 64/159 (40%), Gaps = 33/159 (20%)
Query: 263 VQNLHAYQSGRLSYDQQQQQQQQQQQQQQALQSRHHAQETLHYQN---LAKYQHYGQQGQ 319
+Q+ H +Q + QQQQQQQQQQQQQQ Q +HH H + +YQH QQ Q
Sbjct: 453 LQHRHPHQQQQQQQQQQQQQQQQQQQQQQQQQQQHHHHHHHHLLQDAYMQQYQHATQQQQ 512
Query: 320 GYCQPDAAVRTPEQYYQTFSPSSSHSPARSVGRSPSYSSTPSPLMPNLENFPYSQ----- 374
Q F S + P S + P+ +MP + + Q
Sbjct: 513 -------------MLQQQFLMHSVYQPQPSASQYPT-------MMPQYQQAFFQQQMLAQ 552
Query: 375 -QPLSTGAFPAGITDHSHFMPLLNPSPTDATSSVDTQAG 412
QP A P +T F P L TSS+ Q G
Sbjct: 553 HQPSQQQASPEYLTSPQEFSPAL----VSYTSSLPAQVG 587
>gi|122937241 SH3 and multiple ankyrin repeat domains 3 [Homo sapiens]
Length = 1747
Score = 56.2 bits (134), Expect = 3e-07
Identities = 143/613 (23%), Positives = 215/613 (35%), Gaps = 91/613 (14%)
Query: 835 DRWLEDSRHCC---------STADFGDLPLLPPT------------SRKEDLEAEEEYSS 873
DR LE+ R +A DLP L P+ + DL S+
Sbjct: 1033 DRRLEERRRSTVFLSVGAIEGSAPGADLPSLQPSRSIDERLLGTGPTAGRDLLLPSPVSA 1092
Query: 874 LCELLGSPEQRPGMQD--------PLSPKAPLICTKEEVEEVLDSKAGWGSPCHLSGESV 925
L L+ P P PL P +PL E L S+A SP +
Sbjct: 1093 LKPLVSGPSLGPSGSTFIHPLTGKPLDPSSPLALALAARERALASQAPSRSPTPVHSPDA 1152
Query: 926 ILLGP----TVGTESKVQSWFESSLSHMKP----------GEEGPDGER-APGDS----- 965
GP + + S + S P E+ P ER +P D
Sbjct: 1153 DRPGPLFVDVQARDPERGSLASPAFSPRSPAWIPVPARREAEKVPREERKSPEDKKSMIL 1212
Query: 966 TTSDASLAQKPNKPAVPEAPIAKKEPVPRGKSLRSRRVHRGLPEAEDSPCRAPVLPKDLL 1025
+ D SL Q+P V A +EP G + R G PE +P ++ + +
Sbjct: 1213 SVLDTSL-QRPAGLIVVHATSNGQEPSRLGGAEEER---PGTPELAPAPMQSAAVAEP-- 1266
Query: 1026 LPESCTGPPQGQMEGAGAPGRGASEGLPRMC------TRSLTALSEPRTPGPPGLTTTPA 1079
LP PP G AG PG+G+SE P + L++ E + P
Sbjct: 1267 LPSPRAQPPGGTPADAG-PGQGSSEEEPELVFAVNLPPAQLSSSDEETREELARIGLVPP 1325
Query: 1080 PPDKLGGKQRAAFKSGKRVGKPSPKAASSPSN--PAALPVASDSSPMGSKTKETDSPSTP 1137
P + G A +G PSP SP++ P++ P + S S +E D+ S+
Sbjct: 1326 PEEFANGVLLATPLAGP---GPSPTTVPSPASGKPSSEPPPAPESAADSGVEEADTRSSS 1382
Query: 1138 GKDQRSMILRSRTKTQEIFHSKRRRPSEGRLPNCRATKKLLDNSHLPATFKVSSSPQKEG 1197
+ S + S+ ++ LL+ +P K+ SP +G
Sbjct: 1383 DPHLETTSTISTVSSMSTLSSESGELTDTHTSFADGHTFLLEKPPVPPKPKL-KSPLGKG 1441
Query: 1198 RVSQRARVPKPGAGSKLSDRPLHALKRKSAFMAPVPTKKRNLVLRSRSSSSSNASGNGGD 1257
V+ R + K + S+L + HA A A P + R L R G
Sbjct: 1442 PVTFRDPLLKQSSDSELMAQQHHAASAGLA-SAAGPARPRYLFQRRSKLWGDPVESRGLP 1500
Query: 1258 GKEERPEGSPTLFKRMSS--PKKAKPTKGNG-EPATKL-----PPPETPDACLKLASRAA 1309
G E + PT+ +SS + K T+ G EP L P ++P A +L S
Sbjct: 1501 GPE---DDKPTVISELSSRLQQLNKDTRSLGEEPVGGLGSLLDPAKKSPIAAARLFSSLG 1557
Query: 1310 FQGAMKTKVLPPRKGRGLKLEAIVQKITSPSLKKFACKAPGASPGNPLSPSLSDKDRGLK 1369
++ + P G G + A +AP +P+ P+ ++ GL
Sbjct: 1558 ELSSISAQRSPGGPGGGAS-----YSVRPSGRYPVARRAP-----SPVKPASLERVEGL- 1606
Query: 1370 GAGGSPVGVEEGL 1382
GAG G GL
Sbjct: 1607 GAGAGGAGRPFGL 1619
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 56.2 bits (134), Expect = 3e-07
Identities = 129/568 (22%), Positives = 206/568 (36%), Gaps = 62/568 (10%)
Query: 764 ELTKGLEQGGKASDGISKGDTHEASACLGFQE-EDPPGEKVASLPGDFKQEEVGGVKEEA 822
E+T+ E+ K +G + E A G +E + PP E+ AS ++E VKEEA
Sbjct: 469 EVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASP----EKEAKSPVKEEA 524
Query: 823 GGLLQCP----EVAKADRWLEDSRHCCSTADFGDLPLLPPTSRKEDLEAEEEYSSLCELL 878
+ E AK+ ++ S A + PP ++ + +EE S E+
Sbjct: 525 KSPAEAKSPEKEEAKSPAEVKSPEKAKSPAK--EEAKSPPEAKSPE---KEEAKSPAEVK 579
Query: 879 GSPEQR--PGMQDPLSP---KAPLICTKEEVEEVLDSKAGWGSPCHLSGESVILLGPTVG 933
SPE+ P ++ SP K+P K V+E S A SP +S +
Sbjct: 580 -SPEKAKSPAKEEAKSPAEAKSPEKA-KSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEK 637
Query: 934 TESKVQSWFESSLSHMKPGEEGPDGERAPGDSTTSDASLAQKPNKPAVPEAPIAKKEPVP 993
+S + +S P +E ++A +K P EA +K P
Sbjct: 638 AKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSP 697
Query: 994 RGKSLRS-RRVHRGLPEAEDSP--CRAPVLPKDLLLPESCTGPPQGQMEGAGAPGRGASE 1050
+ +S + + E SP ++PV ++ PE P + E A +P + S
Sbjct: 698 VKEEAKSPEKAKSPVKEEAKSPEKAKSPV-KEEAKTPEKAKSPVK---EEAKSPEKAKS- 752
Query: 1051 GLPRMCTRSLTALSEPRTPGPPGLTTTPAP--PDKLGGKQRAAFKSGKRVGKPSPKAASS 1108
P E +TP +PA P+K + KS ++ P + A +
Sbjct: 753 --PEKAKTLDVKSPEAKTPAKEE-ARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKA 809
Query: 1109 PSNP------AALPVASDSSPMGSKTKETDSPSTPGKDQRSMILRSRTKTQEIFHSKRRR 1162
P PV + P K KE P K + KT+E SK+
Sbjct: 810 PEKEIPKKEEVKSPVKEEEKPQEVKVKE------PPKKAEEEKAPATPKTEEKKDSKKEE 863
Query: 1163 PSEGRLPNCRATKKLLDNSHLPATFKVSSSPQKEGRVSQRARVPKPGAGSKLSDRPLHAL 1222
+ P + +K P KV + ++E ++ P+ A +K+ +
Sbjct: 864 APKKEAPKPKVEEKKEPAVEKPKESKVEAK-KEEAEDKKKVPTPEKEAPAKVEVKEDAKP 922
Query: 1223 KRKSAFMAPVPTKKRNLVLRSRSSSSSNASGNGGDGKEER---PEGSP-----------T 1268
K K+ P + S+ + A+ D KEE+ PE P T
Sbjct: 923 KEKTEVAKKEPDDAKAKE-PSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKT 981
Query: 1269 LFKRMSSPKKAKPTKGNGEPATKLPPPE 1296
L K S PK K K + PPE
Sbjct: 982 LSKEPSKPKAEKAEKSSSTDQKDSKPPE 1009
Score = 42.7 bits (99), Expect = 0.003
Identities = 109/562 (19%), Positives = 180/562 (32%), Gaps = 94/562 (16%)
Query: 1085 GGKQRAAFKSGKRVGKPSPKAASSPSNPAALPVASDS-SPMGSKTKETDSPSTPGKDQRS 1143
GG++ A + P + A+SP A PV ++ SP +K+ E + +P +
Sbjct: 488 GGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAE---- 543
Query: 1144 MILRSRTKTQEIFHSKRRRPSEGRLPNCRATKKLLDNSHLPATFKVSSSPQKEGRVSQRA 1203
++S K + + + P E + SP+KE S
Sbjct: 544 --VKSPEKAKSPAKEEAKSPPEAK------------------------SPEKEEAKSPAE 577
Query: 1204 RVPKPGAGSKLSDRPLHALKRKSAFMAPVPTKKRNLVLRSRSSSSSNASGNGGDGKEERP 1263
A S + + KS A P K+ S + + + K
Sbjct: 578 VKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEK 637
Query: 1264 EGSPTLFKRMSSPKKAK---------PTKGNGEPATKLPPPETPDACLKLASRA--AFQG 1312
SPT + SP+KAK P K + PE + +K +++ +
Sbjct: 638 AKSPTK-EEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKS 696
Query: 1313 AMKTKVLPPRKGRG-LKLEA---------IVQKITSPSLKKFACKAPGASPGNPLSPSLS 1362
+K + P K + +K EA + ++ +P K K SP SP +
Sbjct: 697 PVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKA 756
Query: 1363 DKDRGLKGAGGSPVGVEEGLVNVGTGQKLPTSGADPLCRN-PTNRSLKGKLMNSKKLSST 1421
K +K EE K P P+ + K L K
Sbjct: 757 -KTLDVKSPEAKTPAKEEAR---SPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEK 812
Query: 1422 DCFKTEAFTSP--------------------EALQPGGTALAPKKRSRKGRAGAHGLSKG 1461
+ K E SP E P KK S+K A K
Sbjct: 813 EIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKP 872
Query: 1462 PLEKRPYLGPALLLTPRDRASGTQGASEDNSGGGGKKPKMEELGLASQPPEGRPCQPQTR 1521
+E++ PA+ + + +ED P+ E + +P +
Sbjct: 873 KVEEKK--EPAVEKPKESKVEAKKEEAEDKK--KVPTPEKEAPAKVEVKEDAKPKEKTEV 928
Query: 1522 AQKQPGHTNYSSYSK----------RKRLTRGRAKNTTSSPCKGRAKRRRQQQVLPLDPA 1571
A+K+P SK +K +AK P K AK + + L +P+
Sbjct: 929 AKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKP-KTEAKAKEDDKTLSKEPS 987
Query: 1572 EPEIRLKYISSCKRLRSDSRTP 1593
+P+ K S + DS+ P
Sbjct: 988 KPKAE-KAEKSSSTDQKDSKPP 1008
Score = 36.6 bits (83), Expect = 0.24
Identities = 66/337 (19%), Positives = 120/337 (35%), Gaps = 36/337 (10%)
Query: 339 SPSSSHSPARSVGRSPSYSSTP---SPLMPNLENFPYSQQPLSTGAFPAGITDHSHFMPL 395
SP + SP + +SP + +P P P ++ + + + + + P
Sbjct: 690 SPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAK-SPE 748
Query: 396 LNPSPTDATSSVDTQAGNCKPLQK-------DKLPENLLSDLSLQSLTALTSQVENISNT 448
SP A ++D ++ K K DK PE S + + + S + S
Sbjct: 749 KAKSPEKA-KTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEE----VKSPEKAKSPL 803
Query: 449 VQQLLLSKAAVPQKKGVKNLVSRTPEQHKSQHCSPEGSGYSAEPAGTPLSE--------- 499
+ + +P+K+ VK+ V + + + P + TP +E
Sbjct: 804 KEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEE 863
Query: 500 -PPSSTPQSTHAEPQEADYLSGSEDPLERSFLYCNQARG-------SPARVNSNSKAKPE 551
P P+ E +E E +E + +PA+V AKP+
Sbjct: 864 APKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPK 923
Query: 552 SVSTCSVTSPDDMSTKSDDSFQSLHGSLPLDSFSKFVAGERDCPRLLLSALAQEDLASEI 611
+ + PDD K + P +K ++ + A A+ED +
Sbjct: 924 EKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKED--DKT 981
Query: 612 LGLQEAIGEKADKAWAEAPSLVKDSSKPPFSLENHSA 648
L +E KA+KA + + KDS P + E+ +A
Sbjct: 982 LS-KEPSKPKAEKAEKSSSTDQKDSKPPEKATEDKAA 1017
Score = 35.8 bits (81), Expect = 0.41
Identities = 57/287 (19%), Positives = 96/287 (33%), Gaps = 36/287 (12%)
Query: 1485 QGASEDNSGGGGKKPKMEELGLASQPPEGRPCQPQTRAQKQPGHTNYSSYSKRKRLTRGR 1544
+G E+ + GG ++ K A+ P E P K P + K +
Sbjct: 487 EGGEEEEAEGGEEETKSPPAEEAASP-EKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVK 545
Query: 1545 AKNTTSSPCKGRAKRRRQQQVLPLDPAEPEIRLKYISSCKRLRSDSRTPAFSPFVRVEKR 1604
+ SP K AK + + + A+ +K S ++ +S ++ A SP
Sbjct: 546 SPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVK---SPEKAKSPAKEEAKSPAEAKSPE 602
Query: 1605 DAFTTICTVVNSPGDAPKP----HRKPSSSASSSSSSSSFSLDAAGASLATLPGGSILQP 1660
A + + SP +A P + P+ S + S +A A P
Sbjct: 603 KAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAK-------SP 655
Query: 1661 RPSLPLSSTMHLGPVVSKALSTSCLVCCLCQNPANFKDLGDLCGPYYPEHCLPKKKPKLK 1720
S PV ++A ++P K P K K K
Sbjct: 656 EKEEAKSPEKAKSPVKAEA-----------KSPEKAKS---------PVKAEAKSPEKAK 695
Query: 1721 EKVRPEG-TCEEASLPLERTLKGPECAAAATAGKPPRPDGPADPAKQ 1766
V+ E + E+A P++ K PE A + + P+ P K+
Sbjct: 696 SPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKE 742
Score = 34.3 bits (77), Expect = 1.2
Identities = 73/314 (23%), Positives = 120/314 (38%), Gaps = 42/314 (13%)
Query: 339 SPSSSHSPARSVGRSPSYSSTPSPLMPNLENFPYSQQPLSTGAFPAGITDHSHFMPLLNP 398
SP + SPA+ +SP + +P P + PA S P
Sbjct: 546 SPEKAKSPAKEEAKSPPEAKSPE---KEEAKSPAEVKSPEKAKSPAKEEAKS---PAEAK 599
Query: 399 SPTDATSSVDTQAGNCKPLQ-KDKLPENLLSDLSLQSLTALTSQVENISNTVQQLLLSKA 457
SP A S V +A + P + K + E S ++S S + + + + KA
Sbjct: 600 SPEKAKSPVKEEAKS--PAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPE-----KA 652
Query: 458 AVPQKKGVKN---------LVSRTPEQHKSQHCSPEGSGYSAEPAGTPLSEPPSSTPQST 508
P+K+ K+ +++PE+ KS + S E A +P+ E S ++
Sbjct: 653 KSPEKEEAKSPEKAKSPVKAEAKSPEKAKS---PVKAEAKSPEKAKSPVKEEAKSPEKAK 709
Query: 509 HAEPQEADYLSGSEDPLERSFLYCNQARGSPARVNSNSKAK---PESVSTCSVTSPDDMS 565
+EA ++ P++ +A+ SP + + S K PE T V SP +
Sbjct: 710 SPVKEEAKSPEKAKSPVKEEAKTPEKAK-SPVKEEAKSPEKAKSPEKAKTLDVKSP-EAK 767
Query: 566 TKSDDSFQSLHGSLPLDSFSKFVAGERDCPRLLLSALAQEDLASEILGLQEAIGEKADKA 625
T + + +S P + S V E P S L ++ A E + I +K
Sbjct: 768 TPAKEEARSPADKFPEKAKSP-VKEEVKSPEKAKSPLKEDAKAPE-----KEIPKK---- 817
Query: 626 WAEAPSLVKDSSKP 639
E S VK+ KP
Sbjct: 818 -EEVKSPVKEEEKP 830
>gi|110347429 mediator complex subunit 12 [Homo sapiens]
Length = 2177
Score = 56.2 bits (134), Expect = 3e-07
Identities = 78/320 (24%), Positives = 117/320 (36%), Gaps = 30/320 (9%)
Query: 85 LPTQQGLQGRPAFPGYGVQDSSPYPGRYAGEESLQAWGAPQPPPPQPQPLPAGVAKYDEN 144
LP Q+ L RP +PG + G + QP PQ Q L + +
Sbjct: 1863 LPMQK-LPTRPTYPGVLPTTMTGVMGLEPSSYKTSVYRQQQPAVPQGQRLRQQLQQSQGM 1921
Query: 145 LMKKTA--VPPSRQYAEQGAQ--VPFRTHSLHVQQPPPPQQPLAYPKLQRQKLQNDIASP 200
L + + + PS Y Q +Q P+ +H + +QQ P + P Q Q+ P
Sbjct: 1922 LGQSSVHQMTPSSSYGLQTSQGYTPYVSH-VGLQQHTGPAGTMVPPSYSSQPYQS--THP 1978
Query: 201 LPFPQGTHFPQHSQSFPTSSTYSSSVQGGGQGAHSYKSCTAPTAQPHDR-----PLTA-- 253
P +H Q P+ + + G G S + + T Q P++A
Sbjct: 1979 STNPTLVDPTRHLQQRPSGYVHQQAPTYG-HGLTSTQRFSHQTLQQTPMISTMTPMSAQG 2037
Query: 254 ------SSSLAPGQRVQNLHAYQSGRLSYDQQQQQQQQQ-----QQQQQALQSRHHAQET 302
S+++ P Q+ Q Q + QQQQQQQQQ QQQQQ L+ + Q+
Sbjct: 2038 VQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQ 2097
Query: 303 LHYQNLAKYQHYGQQGQGYCQPDAAVRTPEQYYQTFSPSSSHSPARSVGRSPSYSSTPSP 362
Q + Q QQ Q + Q P Q P + + ++
Sbjct: 2098 QQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQ 2157
Query: 363 LMPNLENFPYSQQPLSTGAF 382
L L N +Q ST F
Sbjct: 2158 LQQQLSN---TQPQPSTNIF 2174
Score = 45.8 bits (107), Expect = 4e-04
Identities = 69/281 (24%), Positives = 95/281 (33%), Gaps = 25/281 (8%)
Query: 74 AADKYHRGSKALPTQQGLQGRPAF------PGYGVQDS---SPYPGRYAGEESLQAWGAP 124
A + R + L QG+ G+ + YG+Q S +PY ++ G
Sbjct: 1904 AVPQGQRLRQQLQQSQGMLGQSSVHQMTPSSSYGLQTSQGYTPYVSHVGLQQHTGPAGTM 1963
Query: 125 QPPPPQPQPLPAGVAKYDENLMKKTAVPPSRQYAEQGAQVPFRTHSLHVQQPPPPQQPLA 184
PP QP + + L+ T R Q P H L Q +
Sbjct: 1964 VPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGL------TSTQRFS 2017
Query: 185 YPKLQRQKLQNDIASPLPFP-QGTHFPQHSQSFPTSSTYSSSVQGGGQGAHSYKSCTAPT 243
+ LQ+ + I++ P QG S + Q Q +
Sbjct: 2018 HQTLQQTPM---ISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQ 2074
Query: 244 AQPHDRPLTASSSLAPGQRVQNLHAYQSGRLSYDQQQQQQQQQQQQQQALQSRHHAQETL 303
Q H R L Q+ Q Q QQQQQQQQQQQQ Q Q + A
Sbjct: 2075 QQYHIRQQQQQQILRQQQQQQQQQQQQQ-----QQQQQQQQQQQQQHQQQQQQQAAPPQP 2129
Query: 304 HYQNLAKYQHYG-QQGQGYCQPDAAVRTPEQYYQTFSPSSS 343
Q+ ++Q G QQ Q Q A VR +Q P S
Sbjct: 2130 QPQSQPQFQRQGLQQTQQQQQTAALVRQLQQQLSNTQPQPS 2170
>gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]
Length = 788
Score = 56.2 bits (134), Expect = 3e-07
Identities = 93/395 (23%), Positives = 131/395 (33%), Gaps = 62/395 (15%)
Query: 229 GGQGAHSYKSCTAPTAQPHDRPLTASSSLAPGQRVQNLHAYQSGRLSYDQQQQQQQQQQ- 287
G G + TA P + +L Q+ Q Q L QQQQQQQQ Q
Sbjct: 132 GTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQA 191
Query: 288 -------------QQQQALQSRHHAQE---TLHYQNLAKYQHYGQQGQGYCQPDAAVRTP 331
QQQQ LQ + Q+ LH+QN + Q QQ Q Q +
Sbjct: 192 QQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQ 251
Query: 332 EQYYQTFSPSSSHSPARSVGRSPSYSSTPSP---LMPNLENF---------PYSQQPLST 379
+Q Q + + + P P P L L+ P QQP
Sbjct: 252 QQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVA 311
Query: 380 GAFPAGITDHSHFMPLLNPSPTDATSSVDTQAGNCKPLQKDKLP-----ENLLSDLSLQS 434
P+ + S PL++ + + TQ PL+ + P + + Q
Sbjct: 312 QNQPSQLPPQSQTQPLVSQAQALPGQMLYTQ----PPLKFVRAPMVVQQPPVQPQVQQQQ 367
Query: 435 LTALTSQVENISNTVQQLLLS---------KAAVPQKKGVKNLVS------RTPEQHKSQ 479
T+Q + Q++ +A P V + S R P SQ
Sbjct: 368 TAVQTAQAAQMVAPGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQPMAQVSQ 427
Query: 480 HCSPEGSGYS-AEPAGTPLSEPPSSTPQSTHAEP--QEADYLSGSEDPLERSFLYCNQAR 536
P S S + TP S PP P +P Q +S P SFL
Sbjct: 428 SSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFL------ 481
Query: 537 GSPARVNSNSKAKPESVSTCSVTSPDDMSTKSDDS 571
SP+ S S + SV SP ++T + S
Sbjct: 482 PSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPS 516
Score = 42.0 bits (97), Expect = 0.006
Identities = 80/316 (25%), Positives = 109/316 (34%), Gaps = 64/316 (20%)
Query: 78 YHRGSKALPTQQGLQGRPAFPGYGVQDSSPYPGRYAGEESLQAWGA-PQPPPPQPQPLPA 136
+H+ + + QQ R A Q + +++LQA QPP QPQP
Sbjct: 224 HHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQP--- 280
Query: 137 GVAKYDENLMKKTAVPPSRQYAEQGAQVPFRTHSLHVQQPPPPQQPLAY--------PKL 188
PPS+ +Q Q+ H+ H Q PP PQQP P+
Sbjct: 281 ---------------PPSQALPQQLQQMH---HTQHHQPPPQPQQPPVAQNQPSQLPPQS 322
Query: 189 QRQKLQNDIAS----------PLPF---PQGTHFPQHSQSFPTSSTYSSSVQGGGQGAHS 235
Q Q L + + PL F P P T + Q A
Sbjct: 323 QTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPG 382
Query: 236 YKSCTAPTAQ--PHDR---PLTASSSLAPGQRVQNLHAYQSGRLSYDQQQQQQQQQQQQQ 290
+ T AQ H R P T + S P + GR Q Q Q
Sbjct: 383 VQMITEALAQGGMHIRARFPPTTAVSAIPSSSI------PLGR------QPMAQVSQSSL 430
Query: 291 QALQSRHHAQETLHYQNL-AKYQHYGQQGQGYCQPDAAVRT-PEQYYQTFSPSSSHSPAR 348
L S Q+ Q++ Q Q GQ QP++ V + P +F PS S P++
Sbjct: 431 PMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQ 490
Query: 349 S--VGRSPSYSSTPSP 362
S R+P S PSP
Sbjct: 491 SPVTARTPQNFSVPSP 506
Score = 34.3 bits (77), Expect = 1.2
Identities = 18/63 (28%), Positives = 29/63 (46%), Gaps = 10/63 (15%)
Query: 659 PRPGEPEALPDSLQLDKGGNAKDFSPGLFEDPSVAFATPDPKKTTGPLSFGTKPTLGVPA 718
P+PG+P + P+S + S G PS +P P+ + P++ T VP+
Sbjct: 456 PQPGQPSSQPNS----------NVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPS 505
Query: 719 PDP 721
P P
Sbjct: 506 PGP 508
>gi|82534351 microtubule-associated protein tau isoform 1 [Homo
sapiens]
Length = 758
Score = 55.8 bits (133), Expect = 4e-07
Identities = 115/471 (24%), Positives = 172/471 (36%), Gaps = 87/471 (18%)
Query: 950 KPGEEGPDGERAP----GDSTTSDASLA----QKPNKPAVPEAPIAKKEPVPRGKSLRSR 1001
+P E P+G A GD+ + + A Q+P V + + EP P G S
Sbjct: 92 QPHTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLR-EPGPPGLS---H 147
Query: 1002 RVHRGLPEAEDSPCRAPVLPKDLLLPESCTGPPQGQMEGAGAPGRGASEGLPRMCTRSLT 1061
++ G+P A P+LP+ P T P G GR A E L
Sbjct: 148 QLMSGMPGA-------PLLPEG---PREATRQPSGTGPEDTEGGRHAPELLKHQL----- 192
Query: 1062 ALSEPRTPGPPGLTTTPAPPDKLGGKQRAAFKSGKRVGKPSPKAASSPSNPAALPVASDS 1121
L + GPP GGK+R K + +++ S P+ A D
Sbjct: 193 -LGDLHQEGPP--------LKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSKASPAQDG 243
Query: 1122 SPMGSKTKETDS-PSTPGKDQRSMILRSRTKTQ-EIFHSKRRRPSEGRLPNCRATKKLLD 1179
P + +E S P P + + + +K EI S+ PS GR
Sbjct: 244 RPPQTAAREATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKG--------Q 295
Query: 1180 NSHLPATFKVSSSP--QKEGRVSQR----------------ARVPKPGAGSKLSDRPLHA 1221
++ L TF V +P QKE S+ AR P G +K +D P +
Sbjct: 296 DAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGEGPEARGPSLGEDTKEADLPEPS 355
Query: 1222 LKRKSAFMAPVPTKKRNLVLRSRSSSSSNASGNGGDGKEERP---------EGSPTLFKR 1272
K+ +A P R L++R S S G G D K+ + + P L +
Sbjct: 356 EKQPAAAPRGKPVS-RVPQLKARMVSKSK-DGTGSDDKKAKTSTRSSAKTLKNRPCLSPK 413
Query: 1273 MSSPKKAKPTKGNGEPATKLPPPETPDACLKLASRAAFQGAMKTKVLPPRKGRGLKLEAI 1332
+P + P PA PP +P + SR GA + K+ KG K +
Sbjct: 414 HPTPGSSDPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKL----KGADGKTKIA 469
Query: 1333 VQKITSPSLKK---FACKAPGASPGNPLSPSLSDK-----DRGLKGAGGSP 1375
+ +P +K A + P +P P +P S + DR + GSP
Sbjct: 470 TPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSP 520
>gi|56549696 E1A binding protein p400 [Homo sapiens]
Length = 3122
Score = 55.5 bits (132), Expect = 5e-07
Identities = 120/515 (23%), Positives = 171/515 (33%), Gaps = 144/515 (27%)
Query: 113 AGEESLQAWGAPQPPPPQPQPLPAGVAKYDENLMKKTAVPPSRQYAEQGAQVPFRTHSLH 172
A ++ Q QPPPPQPQP P + PP Q G+Q P ++
Sbjct: 2493 ADQQKAQQPAVAQPPPPQPQPPPP----------PQQPPPPLPQPQAAGSQPPAGPPAVQ 2542
Query: 173 VQQPPPPQ---QPLAYPKLQR--------------------------------------- 190
Q P PQ QP+ P +
Sbjct: 2543 PQPQPQPQTQPQPVQAPAKAQPAITTGGSAAVLAGTIKTSVTGTSMPTGAVSGNVIVNTI 2602
Query: 191 --------QKLQNDIASP-----LPFPQG--------THFPQHSQSFPTSSTYSSSVQGG 229
Q + +ASP L P G T P + P ++T
Sbjct: 2603 AGVPAATFQSINKRLASPVAPGALTTPGGSAPAQVVHTQPPPRAVGSPATATPDLVSMAT 2662
Query: 230 GQGAHSYKSCTAPTA--------QPHDRPLTASSSLA-----PGQRVQNLHAYQSGRLSY 276
QG + S TA Q R L S A PG+ + H +
Sbjct: 2663 TQGVRAVTSVTASAVVTTNLTPVQTPARSLVPQVSQATGVQLPGKTITPAHFQLLRQQQQ 2722
Query: 277 DQQQQQQQQQQQQQQALQSRHHAQETLHYQNLAKYQHYGQ-------QGQGYCQPDAAVR 329
QQQQQQQQQQQQQQ Q + Q+T + Q GQ + G P+ ++
Sbjct: 2723 QQQQQQQQQQQQQQQQQQQQQQQQQTTTTSQVQVPQIQGQAQSPAQIKAVGKLTPEHLIK 2782
Query: 330 TPEQYYQTFSPSSSHSPARSVGRSPSYSSTPSPLMPNLENFPYSQQPLST-------GAF 382
+Q Q P A+S P+ P P Q P T GA
Sbjct: 2783 MQKQKLQ-MPPQPPPPQAQSAPPQPTAQVQVQTSQP-----PQQQSPQLTTVTAPRPGAL 2836
Query: 383 PAGITDHSHFMPLLNPSPT---DATSSVDTQAGNCKPLQKDKLPENLL--SDLSLQSLTA 437
G T + + L PT A + TQA + K P + + +S +T
Sbjct: 2837 LTGTTVANLQVARLTRVPTSQLQAQGQMQTQAPQPAQVALAKPPVVSVPAAVVSSPGVTT 2896
Query: 438 LTSQVENISNTV------------------QQLL-LSKAAVPQKKGVKNLVSRTP----E 474
L V IS + QQLL L + AV Q+K ++ ++ P +
Sbjct: 2897 LPMNVAGISVAIGQPQKAAGQTVVAQPVHMQQLLKLKQQAVQQQKAIQPQAAQGPAAVQQ 2956
Query: 475 QHKSQHCSPEGS----GYSAEPA------GTPLSE 499
+ +Q + G+ Y+A+PA TP+S+
Sbjct: 2957 KITAQQITTPGAQQKVAYAAQPALKTQFLTTPISQ 2991
Score = 40.8 bits (94), Expect = 0.013
Identities = 62/241 (25%), Positives = 88/241 (36%), Gaps = 31/241 (12%)
Query: 85 LPTQQGLQGRPAFPGY----GVQDSSPYPGRYAGEESLQAWGAPQPPPPQPQPLP-AGVA 139
+PT QG G P P G + S G A P P P LP AGV
Sbjct: 509 MPTAQG--GMPPTPQAAQLAGQRQSQQQYDPSTGPPVQNAASLHTPLPQLPGRLPPAGVP 566
Query: 140 KYDENLMKKTAVPPSRQYAEQGAQVPFRTHSLHVQQPPPPQQPLAYPKLQRQKLQNDIAS 199
+ + A P A+ Q+P +T +V P PP L P Q +L + +
Sbjct: 567 TAALSSALQFAQQPQVVEAQTQLQIPVKTQQPNVPIPAPPSSQLPIPPSQPAQLALHVPT 626
Query: 200 P----LPFPQGTHFPQHSQS--------------FPTSSTYS-SSVQGGGQGAHSYKSCT 240
P + Q + PQ S PTSST S + V G G G +S
Sbjct: 627 PGKVQVQASQLSSLPQMVASTRLPVDPAPPCPRPLPTSSTSSLAPVSGSGPGPSPARS-- 684
Query: 241 APTAQPH---DRPLTASSSLAPGQRVQNLHAYQSGRLSYDQQQQQQQQQQQQQQALQSRH 297
+P +P ++ L+ +S PG QS + Q Q +Q L+++
Sbjct: 685 SPVNRPSSATNKALSPVTSRTPGVVASAPTKPQSPAQNATSSQDSSQDTLTEQITLENQV 744
Query: 298 H 298
H
Sbjct: 745 H 745
Score = 32.0 bits (71), Expect = 5.9
Identities = 42/180 (23%), Positives = 69/180 (38%), Gaps = 24/180 (13%)
Query: 974 QKPNKPAVPEAPIAKKEPVPRGKSLRSRRVHRGLPEAEDSPCRAPVLPKDLLLPESCTGP 1033
QK +PAV + P + +P P ++ LP+ + + + P P +
Sbjct: 2496 QKAQQPAVAQPPPPQPQPPP-----PPQQPPPPLPQPQAAGSQPPA------GPPAVQPQ 2544
Query: 1034 PQGQMEGAGAPGRGASEGLPRMCTRSLTAL-------SEPRTPGPPGLTTTPAPPDKLGG 1086
PQ Q + P + ++ P + T A+ S T P G + + + G
Sbjct: 2545 PQPQPQTQPQPVQAPAKAQPAITTGGSAAVLAGTIKTSVTGTSMPTGAVSGNVIVNTIAG 2604
Query: 1087 KQRAAFKS-GKRVGKP-SPKAASSPSNPAALPVASDSSPMGSKTKETDSPSTPGKDQRSM 1144
A F+S KR+ P +P A ++P A V P + SP+T D SM
Sbjct: 2605 VPAATFQSINKRLASPVAPGALTTPGGSAPAQVVHTQPP----PRAVGSPATATPDLVSM 2660
>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
preproprotein [Homo sapiens]
Length = 331
Score = 54.7 bits (130), Expect = 9e-07
Identities = 55/176 (31%), Positives = 67/176 (38%), Gaps = 26/176 (14%)
Query: 974 QKPNKPAVPEAPIAKKEPVPRGKSLRSRRVHRGLPEAE-----DSPCRAPVLPKDLLLPE 1028
Q NKP P P + P P+G RS R G P+ + P P P P
Sbjct: 63 QGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP- 121
Query: 1029 SCTGPPQGQMEGAGAPGRGASEGLPRMCTRSLTALSEPRTP-GPP--GLTTTPAPPDKLG 1085
PPQG G P G +G P +S + S P P GPP G PP G
Sbjct: 122 ----PPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPG 177
Query: 1086 GKQRAAFKSGKRVGKPSPKAASSPSNPAALPVASDSSPMGSKTKETDSPSTPGKDQ 1141
Q + GK+ P P P P P P G K++ + SP PGK Q
Sbjct: 178 KPQGPPPQGGKKPQGPPP-----PGKPQGPP------PQGDKSRSSQSP--PGKPQ 220
Score = 52.0 bits (123), Expect = 6e-06
Identities = 52/188 (27%), Positives = 67/188 (35%), Gaps = 29/188 (15%)
Query: 974 QKPNKPAVPEAPIAKKEPVPRGKSLRSRRVHRGLPEAE-----DSPCRAPVLPKDLLLPE 1028
Q N+P P P + P P+G RS R G P+ + P P P P
Sbjct: 124 QGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP- 182
Query: 1029 SCTGPPQGQMEGAGAPGRGASEGLPRMCTRSLTALSEPRTP------------GPPGLTT 1076
PPQG + G P G +G P +S ++ S P P GPP
Sbjct: 183 ----PPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPG 238
Query: 1077 TP-APPDKLGGKQRAAFKSGKRVGKP------SPKAASSPSNPAALPVASDSSPMGSKTK 1129
P PP + G K + GK G P S A S P P P ++P G
Sbjct: 239 KPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPP 298
Query: 1130 ETDSPSTP 1137
+P P
Sbjct: 299 AGGNPQQP 306
Score = 42.0 bits (97), Expect = 0.006
Identities = 37/112 (33%), Positives = 44/112 (39%), Gaps = 16/112 (14%)
Query: 1033 PPQGQMEGAGAPGRGASEGLPRMCTRSLTALSEPRTP-GPP--GLTTTPAPPDKLGGKQR 1089
PPQG + G P G +G P +S + S P P GPP G PP G Q
Sbjct: 61 PPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQG 120
Query: 1090 AAFKSGKRVGKPSPKAASSPSNPAALPVASDSSPMGSKTKETDSPSTPGKDQ 1141
+ G R P P P P P P G K++ SP PGK Q
Sbjct: 121 PPPQGGNRPQGPPP-----PGKPQGPP------PQGDKSRSPRSP--PGKPQ 159
Score = 33.9 bits (76), Expect = 1.6
Identities = 42/145 (28%), Positives = 49/145 (33%), Gaps = 30/145 (20%)
Query: 92 QGRPAFPGYGVQDSSPYPGRYAGE--------ESLQAWGAPQPPPPQ---------PQPL 134
QG P G Q P PG+ G + G PQ PPPQ P
Sbjct: 159 QGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGK 218
Query: 135 PAGVAKYDENLMKKTAVPPSRQYAE--QGAQVPFRTHSLHVQQPPPPQQPLAYPKLQRQK 192
P G N + PP + QG P Q PPPP +P P K
Sbjct: 219 PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKP--------QGPPPPGKPQGPPAQGGSK 270
Query: 193 LQNDIASPLPFPQGTHFPQHSQSFP 217
Q+ SP PQG PQ + P
Sbjct: 271 SQS-ARSPPGKPQGP--PQQEGNNP 292
Score = 32.0 bits (71), Expect = 5.9
Identities = 46/164 (28%), Positives = 58/164 (35%), Gaps = 22/164 (13%)
Query: 92 QGRPAFPGYGVQDSSPYPGRYAGEESLQAWGAPQPPPPQ----PQ-PLPAGVAKYDENLM 146
QG P G Q P PG+ PQ PPPQ PQ P P G +
Sbjct: 98 QGPPPQGGNQPQGPPPPPGK------------PQGPPPQGGNRPQGPPPPGKPQGPPPQG 145
Query: 147 KKTAVPPSRQYAEQGAQVPFRTHSLHVQQPPPPQQPLAYPKLQRQKLQNDIASPLPFPQG 206
K+ P S QG P + + PPPP +P P +K Q P PQG
Sbjct: 146 DKSRSPRSPPGKPQGP--PPQGGNQPQGPPPPPGKPQGPPPQGGKKPQG--PPPPGKPQG 201
Query: 207 THFPQHSQSFPTSSTYSSSVQGGGQGAHSYKSCTAPTAQPHDRP 250
PQ +S + S QG + + P +P P
Sbjct: 202 PP-PQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP 244
>gi|33286444 mastermind-like 2 [Homo sapiens]
Length = 1156
Score = 54.3 bits (129), Expect = 1e-06
Identities = 105/450 (23%), Positives = 151/450 (33%), Gaps = 75/450 (16%)
Query: 123 APQPPPPQPQPLPAGVAKYDENLMKKTAVPPSRQYAEQGAQVPFRTHSLHVQQPPPPQQP 182
+P P PQ Q P + L V ++Q + A R +QQ QP
Sbjct: 402 SPIPSVPQSQAQPQTGSGASRALPSWQEVSHAQQLKQIAAN---RQQHARMQQHQQQHQP 458
Query: 183 LAYPKLQRQKLQNDIASPLPFPQGTH-FPQHSQSFPTSSTYSSSVQG--GGQGAH----S 235
+ L A P P P G P S T S SS + G GG G +
Sbjct: 459 TNWSALPSS------AGPSPGPFGQEKIPSPSFGQQTFSPQSSPMPGVAGGSGQSKVMAN 512
Query: 236 YKSCTAPTAQ----------------------PHD---------RPLTASSSLAPGQRVQ 264
Y P+AQ PH +PL +S Q++
Sbjct: 513 YMYKAGPSAQGGHLDVLMQQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQMP 572
Query: 265 NLHAYQS--GRLSYDQQQQQQQQQQQQQQALQSRHHAQETLHYQNLAKYQHYG------- 315
++ Q+ L Y QQQQQQQQQQQQQQ Q + Q+ Q +
Sbjct: 573 SVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQ 632
Query: 316 -------QQGQGYCQPDAAVRTPEQYYQTFSPSSSHSPARSVGRSPSYSSTPSPLMPNLE 368
QQ Q Q + +Q Q S PA+S+ P S P PL L
Sbjct: 633 QSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRS-PLPLQQKLL 691
Query: 369 NFPYSQQPLSTGAFPAG----ITDHSHFMPLLNPSPTDATSSVDTQAGNCKPLQKDKLPE 424
QP++ + HS PSP+ S Q+ L +
Sbjct: 692 LQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQQSLLNQ 751
Query: 425 NLLSDLSLQSLTALTSQVENISNTVQQLLLSKAAVPQKKGVKNLVSRTPEQHKSQHCSPE 484
L+ Q+L + + QQ+L + + + +SR P +K Q +
Sbjct: 752 QLMG--KKQTLQRQIMEQKQQLLLQQQMLADAEKIAPQDQINRHLSRPPPDYKDQRRNVG 809
Query: 485 GSGYSAEPAG-----TPLSEPPSSTPQSTH 509
+A+ +G + S + P STH
Sbjct: 810 NMQPTAQYSGGSSTISLNSNQALANPVSTH 839
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 54.3 bits (129), Expect = 1e-06
Identities = 109/559 (19%), Positives = 190/559 (33%), Gaps = 63/559 (11%)
Query: 1085 GGKQRAAFKSGKRVGKPSPKAASSPSNPAALPVASDSSPMGSKTKETDSPSTPGKDQRSM 1144
G + A KRVG P KAA+ S ++ +SD + K+ P G ++
Sbjct: 99 GPPAKKAAVPAKRVGLPPGKAAAKASESSSSEESSDDDDEEDQKKQ---PVQKGVKPQAK 155
Query: 1145 ILRSRTKTQEIFHSKRRRPSEGRLPNCRATKKLLDNSHLPATFKVSS-SPQKEGRVSQRA 1203
++ K + S SE P + K P T K + +P K R + +
Sbjct: 156 AAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKIT------PVTVKAQTKAPPKPARAAPKI 209
Query: 1204 RVPKPGAGSKLSDRPLHALKRKSAFMAPVPTK---KRNLVLRSRSSSSSNASGNGGDGKE 1260
K + S S + + A P K K+ +V ++ +++ + ++
Sbjct: 210 ANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSED 269
Query: 1261 ERPEGSPTLFKRMSSPKKAKPTKGNGEPATKLPPPETPDACLKLASRAAFQGAMKTKVLP 1320
+ ++ KP K P + +PPP P L ++ + K + +
Sbjct: 270 SSSD---------EEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVE 320
Query: 1321 PRKGRGLKLEAIVQKITSPSLK----KFACKAPGASPGNPLSPSLSDKDRG--------- 1367
+ + ++ ++ P K K K P A S SD D
Sbjct: 321 SSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKP 380
Query: 1368 ---LKGAGGSP-VGVEEGLVNVGTGQKLPTSGADPLCRNPTNRSLKGKLMNSKKLSSTDC 1423
K + P V + V K P G L + S + +S + T
Sbjct: 381 AGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTK- 439
Query: 1424 FKTEAFTSPEALQPGGTALAPKKRSRKGRAGA------------HGLSKGPLEKRP--YL 1469
K A T P+A +L K+ + R + SK ++K+P
Sbjct: 440 -KMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVA 498
Query: 1470 GPALLLTPRDRASGTQGASEDNSGGGGKKPKMEELGLASQPPEGRPCQPQTRAQKQPGHT 1529
G A P G +S +S + + E+L P RP P+
Sbjct: 499 GGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKGSP---RPQAPKANGTSALTAQ 555
Query: 1530 NYSSYSKRKRLTRGRAKNTTSSPCKGRAKRRRQQQVL--PLDPAEPEIRLKYISSC-KRL 1586
N + + + K G K+R+Q + P +I+L+ ++ KR
Sbjct: 556 NGKAAKNSEEEEEEKKKAAVVVSKSGSLKKRKQNEAAKEAETPQAKKIKLQTPNTFPKRK 615
Query: 1587 RSDSRTPAFSPFVRVEKRD 1605
+ + R A SPF RV + +
Sbjct: 616 KGEKR--ASSPFRRVREEE 632
Score = 52.4 bits (124), Expect = 4e-06
Identities = 83/393 (21%), Positives = 140/393 (35%), Gaps = 46/393 (11%)
Query: 930 PTVGTESKVQSWFESSLSHMKP--GEEGPDGERAPGDSTTSDASLAQKPNKPAVPEAPIA 987
PT + S S + KP + GP P + SL +P K AV
Sbjct: 260 PTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVE----- 314
Query: 988 KKEPVPRGKSLRSRRVHRGLPEAEDSPCRAPVLPKDLLLPESCTGPPQGQMEGAGAPGRG 1047
K++PV + S E E P V+ K P + + + +
Sbjct: 315 KQQPVESSED--SSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSE 372
Query: 1048 ASEGLPRMCTRSLTALSEPR-TPGPPGLTTTPAPPDKLGGKQRAAF-------------- 1092
E + + + ++P T P + AP +GG Q+
Sbjct: 373 DDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSS 432
Query: 1093 ----KSGKRVGKPSPKAASSPSNPAALPVASDSSPMGSKTKETDSPSTPGKDQRSMILRS 1148
K+ K V PKA + AAL + + +P GS+ +DS S+ +++ +S
Sbjct: 433 SEEEKTKKMVATTKPKATAK----AALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKS 488
Query: 1149 RTKTQEIFHSKRRRPSEGRLPNCRATKKLLDNSHLPATFKVSSSPQKE----GRVSQRAR 1204
K K ++ + G P+ A+ K ++ SS ++E G+ S R +
Sbjct: 489 AVK------KKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKGSPRPQ 542
Query: 1205 VPKPGAGSKLSDRPLHALKRKSAFMAPVPTKKRNLVLRSRSSSSSNASGNGGDGKEERPE 1264
PK S L+ + A K KK+ V+ S+S S N + E P+
Sbjct: 543 APKANGTSALTAQNGKAAKNSE---EEEEEKKKAAVVVSKSGSLKKRKQNEAAKEAETPQ 599
Query: 1265 GSPTLFKRMSS-PKKAKPTKGNGEPATKLPPPE 1296
+ ++ PK+ K K P ++ E
Sbjct: 600 AKKIKLQTPNTFPKRKKGEKRASSPFRRVREEE 632
Score = 45.4 bits (106), Expect = 5e-04
Identities = 96/453 (21%), Positives = 165/453 (36%), Gaps = 90/453 (19%)
Query: 950 KPGEEGP---DGERAPGDSTTSDASLA---QKPNKPAVPEAPIAKKEPV----------P 993
KP P +G+ A S++S +S + ++ A P+ + KK+ V P
Sbjct: 201 KPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTP 260
Query: 994 RGKSLRSRRVHRGLPEAEDSPCRAPVLPKDLLLPESCTGPPQGQMEGAGAPGRGASEGLP 1053
KS S E + P + P + P S PP + G P + + P
Sbjct: 261 TRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPS--APPPKKSLGTQPPKKAVEKQQP 318
Query: 1054 RMCTRSLTALSE--------PRTPGPPGLTTTPAPPDKLGGK-------------QRAAF 1092
+ + S+ P T TT PP K + A
Sbjct: 319 VESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPS 378
Query: 1093 KSGKRVGKPSPKAASSPSNPAALPVASDSSPMGS----KTKETDSPSTPGKDQRSMILRS 1148
K S K A + +PA P A+ P+G T++ DS S+ + S
Sbjct: 379 KPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSS----E 434
Query: 1149 RTKTQEIFHSKRRRPSEG---RLPNCRATKKLLDNSHLPATFKVSSSPQKEGRVSQRA-- 1203
KT+++ + + + + LP +A + D+S + SSS ++E + S+ A
Sbjct: 435 EEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSS---SDSDSSSSEEEEEKTSKSAVK 491
Query: 1204 RVPKPGAGSKLSDRPLHALKRKSAFMAPVPTKKRNLVLRSRSSSSSNASGNGGDGKEERP 1263
+ P+ AG +P A K K+ SS+S++S + + +EE+
Sbjct: 492 KKPQKVAGGAAPSKPASAKKGKA------------------ESSNSSSSDDSSEEEEEKL 533
Query: 1264 EGSPTLFKRMSSPK---KAKPTKGNGEPATKLPPPETPDACLKLASRAAFQGAMKTKVLP 1320
+G + R +PK + T NG+ A E + K A + G++K +
Sbjct: 534 KGKGS--PRPQAPKANGTSALTAQNGKAAKN--SEEEEEEKKKAAVVVSKSGSLKKR--- 586
Query: 1321 PRKGRGLKLEAIVQKITSPSLKKFACKAPGASP 1353
K ++ +P KK + P P
Sbjct: 587 -------KQNEAAKEAETPQAKKIKLQTPNTFP 612
Score = 31.6 bits (70), Expect = 7.7
Identities = 74/325 (22%), Positives = 111/325 (34%), Gaps = 57/325 (17%)
Query: 1459 SKGPLEKRPYLGPALLLTPRDRASGTQGASEDNSGGGGKKPKMEELGLASQPPEGRPCQP 1518
+K P K GP + + + + SED+S EE PP + P
Sbjct: 61 AKVPERKLQANGP---VAKKAKKKASSSDSEDSS---------EEEEEVQGPPAKKAAVP 108
Query: 1519 QTRAQKQPGHTNYSSYSKRKRLTRGRAKNTTSSPCKGRAKRRRQQQVLPLDPA-EPEIRL 1577
R PG +A ++SS Q+ P+ +P+ +
Sbjct: 109 AKRVGLPPGKA------------AAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKA 156
Query: 1578 KYISSCKRLRSDSRTPAFSPFVRVEKRDAFTTICTVVNSPGDAPKPHRKP-------SSS 1630
K SDS + + S + + T TV PKP R ++S
Sbjct: 157 AKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAAS 216
Query: 1631 ASSSSSSSSFSLDAAGASLATLPGGSILQPRPSLPLSSTMHLGPVVSKAL----STSCLV 1686
+SSSSSSSS S D+ A P+ ++P + PV + S+S
Sbjct: 217 SSSSSSSSSSSDDSEEEKAAA-------TPKKTVPKKQVVAKAPVKAATTPTRKSSSSED 269
Query: 1687 CCLCQNPANFKDLGDLCGPYY---PEHCLPKKK-------PKLKEKVRP----EGTCEEA 1732
+ K + + GPY P P KK K EK +P E + +E+
Sbjct: 270 SSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDES 329
Query: 1733 SLPLERTLKGPECAAAATAGKPPRP 1757
E K P A + A P P
Sbjct: 330 DSSSEEEKKPPTKAVVSKATTKPPP 354
>gi|178557734 microtubule-associated protein tau isoform 6 [Homo
sapiens]
Length = 776
Score = 53.9 bits (128), Expect = 1e-06
Identities = 110/453 (24%), Positives = 165/453 (36%), Gaps = 82/453 (18%)
Query: 950 KPGEEGPDGERAP----GDSTTSDASLA----QKPNKPAVPEAPIAKKEPVPRGKSLRSR 1001
+P E P+G A GD+ + + A Q+P V + + EP P G S
Sbjct: 92 QPHTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLR-EPGPPGLS---H 147
Query: 1002 RVHRGLPEAEDSPCRAPVLPKDLLLPESCTGPPQGQMEGAGAPGRGASEGLPRMCTRSLT 1061
++ G+P A P+LP+ P T P G GR A E L
Sbjct: 148 QLMSGMPGA-------PLLPEG---PREATRQPSGTGPEDTEGGRHAPELLKHQL----- 192
Query: 1062 ALSEPRTPGPPGLTTTPAPPDKLGGKQRAAFKSGKRVGKPSPKAASSPSNPAALPVASDS 1121
L + GPP GGK+R K + +++ S P+ A D
Sbjct: 193 -LGDLHQEGPP--------LKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSKASPAQDG 243
Query: 1122 SPMGSKTKETDS-PSTPGKDQRSMILRSRTKTQ-EIFHSKRRRPSEGRLPNCRATKKLLD 1179
P + +E S P P + + + +K EI S+ PS GR
Sbjct: 244 RPPQTAAREATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKG--------Q 295
Query: 1180 NSHLPATFKVSSSP--QKEGRVSQR----------------ARVPKPGAGSKLSDRPLHA 1221
++ L TF V +P QKE S+ AR P G +K +D P +
Sbjct: 296 DAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGEGPEARGPSLGEDTKEADLPEPS 355
Query: 1222 LKRKSAFMAPVPTKKRNLVLRSRSSSSSNASGNGGDGKEERP---------EGSPTLFKR 1272
K+ +A P R L++R S S G G D K+ + + P L +
Sbjct: 356 EKQPAAAPRGKPVS-RVPQLKARMVSKSK-DGTGSDDKKAKTSTRSSAKTLKNRPCLSPK 413
Query: 1273 MSSPKKAKPTKGNGEPATKLPPPETPDACLKLASRAAFQGAMKTKVLPPRKGRGLKLEAI 1332
+P + P PA PP +P + SR GA + K+ KG K +
Sbjct: 414 HPTPGSSDPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKL----KGADGKTKIA 469
Query: 1333 VQKITSPSLKK---FACKAPGASPGNPLSPSLS 1362
+ +P +K A + P +P P +P S
Sbjct: 470 TPRGAAPPGQKGQANATRIPAKTPPAPKTPPSS 502
Score = 45.1 bits (105), Expect = 7e-04
Identities = 167/755 (22%), Positives = 252/755 (33%), Gaps = 160/755 (21%)
Query: 815 VGGVKEEAGGLLQCPEVAKADRWLEDSRHCCSTADFGDLPLLPPTSRKEDLEAEEEYSSL 874
+G K++ G + + D L++S T D + P + K AE+ + L
Sbjct: 20 LGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPL 79
Query: 875 CELLGSPEQRPGMQDPLSPKAPLICTKEEVEEVLDSKAGWGSPCHLSGESVILLGPTVGT 934
+ E PG Q P E E +AG G L E+ + +
Sbjct: 80 VD-----EGAPGKQAAAQPHT------EIPEGTTAEEAGIGDTPSLEDEAAGHVTQEPES 128
Query: 935 ESKVQSWFESSLSHMKPGEEGPDGERAPGDSTTSDASLAQKPNKPAVPEAPI-AKKEPVP 993
VQ F R PG S ++ P P +PE P A ++P
Sbjct: 129 GKVVQEGFL----------------REPGPPGLSHQLMSGMPGAPLLPEGPREATRQPSG 172
Query: 994 RGKSLRSRRVHRGLPEAEDSPCRAPVLPKDLLLPE-SCTGPPQGQMEGAGAPG------- 1045
G PE + AP L K LL + GPP G PG
Sbjct: 173 TG------------PEDTEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKEEVDE 220
Query: 1046 -RGASEGLPRMCTRSLTALSE----PRT--------PGPPGLTTTPAPPD---KLGGKQR 1089
R E P+ S + ++ P+T PG P P P D K+ +
Sbjct: 221 DRDVDESSPQDSPPSKASPAQDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSKVSTEIP 280
Query: 1090 AAFKSGKRVGK-----------------PSPKAASSPSNP----AALPVASDSSP----- 1123
A+ G VG+ P+ + + S AA P A P
Sbjct: 281 ASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGEGPEARGP 340
Query: 1124 -MGSKTKETDSPSTPGKDQRSMILRSRTKTQEIFHSKRRRPSEGRLPNCRATKKLLDNSH 1182
+G TKE D P P + Q + R + ++ + K R S+ + KK ++
Sbjct: 341 SLGEDTKEADLPE-PSEKQPAAAPRGKPVSR-VPQLKARMVSKSKDGTGSDDKKAKTSTR 398
Query: 1183 LPATFKVSSSPQKEGRVSQRARVPKPGAGSKLSDRPLHALKRKSAFMAPVPTKK----RN 1238
SS+ + R + P PG+ L ++ S + P P +
Sbjct: 399 -------SSAKTLKNRPCLSPKHPTPGSSDPL-------IQPSSPAVCPEPPSSPKHVSS 444
Query: 1239 LVLRSRSSSSSNASGNGGDGKEERPEGSPTLFKRMSSPKKAKPTKGNGEPATKLPPPETP 1298
+ R+ SS + G DGK ++++P+ A P G+ P +TP
Sbjct: 445 VTSRTGSSGAKEMKLKGADGKT-----------KIATPRGAAPPGQKGQANATRIPAKTP 493
Query: 1299 DACLKLASRAAFQGAMKTKVLPPRKGRGLKLEAIVQKITSPSLKKFACKAPGASPGNPLS 1358
A S A Q + PR RG K ++ +SPG+P +
Sbjct: 494 PAPKTPPSSATKQVQRRPPPAGPRSERG-------------EPPKSGDRSGYSSPGSPGT 540
Query: 1359 PSLSDKDRGLKGAGGSPVGVEEGLVNVGTGQKLPTSGADPLCRNPTNRSLKGKLMNSK-K 1417
P + L P + + V T K P+S L P L N K K
Sbjct: 541 PGSRSRTPSLP---TPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMP---DLKNVKSK 594
Query: 1418 LSSTDCFKTEAFTSPEALQPGG--TALAPKKRSRKGRAGAHGLSKGPLEKRPYLGPA-LL 1474
+ ST+ K QPGG + KK G SK ++ P G ++
Sbjct: 595 IGSTENLKH---------QPGGGKVQIINKKLDLSNVQSKCG-SKDNIKHVPGGGSVQIV 644
Query: 1475 LTPRDRAS-----GTQGASEDNSGGGGKKPKMEEL 1504
P D + G+ G GGG + K E+L
Sbjct: 645 YKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKL 679
>gi|55956910 meningioma 1 [Homo sapiens]
Length = 1320
Score = 53.9 bits (128), Expect = 1e-06
Identities = 88/354 (24%), Positives = 118/354 (33%), Gaps = 113/354 (31%)
Query: 57 PSYEGGAGTPSGT----------AAAVAADKYHRGSKALPTQQGLQGRPAFPGYGVQDSS 106
P Y G P G A V K H A P QQ Q + P Q
Sbjct: 257 PHYAAGRQVPGGAFPGASAMPRAAGMVGLSKMH----AQPPQQQPQQQQQ-PQQQQQQHG 311
Query: 107 PYPGRYAGEESLQAWGAPQ--------------PPPPQPQ----------PLPAGVAKYD 142
+ R++G + P PPPPQ Q P P G+
Sbjct: 312 VFFERFSGARKMPVGLEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGL---- 367
Query: 143 ENLMKKTAVPPSRQYAEQG--------------------AQVPFRTHSLH---------- 172
L+++ + PP+ +QG AQ + H L
Sbjct: 368 --LVRQNSCPPALPRPQQGEAGTPSGGLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSEP 425
Query: 173 ---VQQPPPPQQPLAYPKLQRQKLQNDIASP-LPFPQGTHFP-QHSQSFPTSSTYSSSVQ 227
+Q PPP Q P Q+LQ+ A P + + F S ++++ S+
Sbjct: 426 VFSMQHPPPQQAP-------NQRLQHFDAPPYMNVAKRPRFDFPGSAGVDRCASWNGSMH 478
Query: 228 GGGQGAHSYKSC----------TAPTAQPHDRPLTASSSLAPGQRVQNLHAYQSGRLSYD 277
G H S P + P PL P Q+L Q +
Sbjct: 479 NGALDNHLSPSAYPGLPGEFTPPVPDSFPSGPPLQ-----HPAPDHQSLQQQQQQQQQQQ 533
Query: 278 QQQQQQQQQQQQQQALQSRHHA-----------QETLHYQNLAKYQHYGQQGQG 320
QQQQQQQQQQQQQQ Q ++ A Q+ L NLA+ H G GQG
Sbjct: 534 QQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNLAQLGHPGDVGQG 587
Score = 50.1 bits (118), Expect = 2e-05
Identities = 67/246 (27%), Positives = 92/246 (37%), Gaps = 64/246 (26%)
Query: 124 PQPPPPQPQPLPAGVAKYDENLMKKTAVPPSRQYAEQG--------------------AQ 163
PQ PP Q P P G+ L+++ + PP+ +QG AQ
Sbjct: 353 PQQPPQQQPPPPPGL------LVRQNSCPPALPRPQQGEAGTPSGGLQDGGPMLPSQHAQ 406
Query: 164 VPFRTHSLH-------------VQQPPPPQQPLAYPKLQRQKLQNDIASPLPFPQGTHFP 210
+ H L +Q PPP Q P Q+LQ+ A P + P
Sbjct: 407 FEYPIHRLENRSMHPYSEPVFSMQHPPPQQAP-------NQRLQHFDAPP--YMNVAKRP 457
Query: 211 QHSQSFPTSS------TYSSSVQGGGQGAHSYKSCTAPTAQPHDRPLTASSSLAPGQRVQ 264
+ FP S+ +++ S+ G H S +A P + S G +Q
Sbjct: 458 RFD--FPGSAGVDRCASWNGSMHNGALDNHL--SPSAYPGLPGEFTPPVPDSFPSGPPLQ 513
Query: 265 NLHAYQSGRLSYDQQQQQQQQQQQQQQALQSRHHAQETLHYQNLA---KYQHYGQQGQGY 321
+ S QQQQQQQQQQQQQQ Q + Q+ QN A K Q Q
Sbjct: 514 HP---APDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRL 570
Query: 322 CQPDAA 327
QP+ A
Sbjct: 571 RQPNLA 576
>gi|189491748 ataxin 1 [Homo sapiens]
Length = 815
Score = 53.5 bits (127), Expect = 2e-06
Identities = 94/371 (25%), Positives = 141/371 (38%), Gaps = 72/371 (19%)
Query: 178 PPQQPLAYP---KLQRQKLQNDIASPLPFPQGTHFPQHSQSFPTSSTYSSSVQGGGQGAH 234
PP P + P L +P+ Q H P H+ F SS YS G +
Sbjct: 89 PPSAPRSVPVATTLPAAYATPQPGTPVSPVQYAHLP-HTFQFIGSSQYS-----GTYASF 142
Query: 235 SYKSCTAPTAQPHDRPL-TASSSLAPGQRVQNLHAYQS-----GRLSY------DQQQQQ 282
PTA P + +A+ + P QR Q L AY + G LS +QQQQQ
Sbjct: 143 IPSQLIPPTANPVTSAVASAAGATTPSQRSQ-LEAYSTLLANMGSLSQTPGHKAEQQQQQ 201
Query: 283 QQQQQQQQQALQSRHHAQETLHYQNLAKYQHYGQQGQGYCQPDAAVRTPEQYYQTFSPSS 342
QQQQQQQ Q Q + Q+ Q+L++ G P + + Y S
Sbjct: 202 QQQQQQQHQHQQQQQQQQQQQQQQHLSR-------APGLITPGSPPPAQQNQYVHIS--- 251
Query: 343 SHSPARSVGRSPSYSSTPSPLMPNLENFPYSQQPLSTGAFPAGITDHSHFMPLLNPSPTD 402
S ++ GR+ S + P L P+ P++ L+ G P+
Sbjct: 252 --SSPQNTGRTASPPAIPVHLHPHQTMIPHT---LTLG------------------PPSQ 288
Query: 403 ATSSVDTQAGNCKPLQKDKLPENLLSDLSLQSLTALTSQVENI----SNTVQQLLLSKAA 458
+ P + K E+ ++Q+ L ++E + + L L KA
Sbjct: 289 VVMQYADSGSHFVPREATKKAESSRLQQAIQAKEVLNGEMEKSRRYGAPSSADLGLGKA- 347
Query: 459 VPQKKGVKNLVSRTPEQHKSQHCSPEGSGYSA-EPAGTPLSE---PPSSTPQSTHAEPQE 514
G K++ +H H SP S YS+ +P+G S P S+TP + E Q+
Sbjct: 348 -----GGKSVPHPYESRHVVVHPSP--SDYSSRDPSGVRASVMVLPNSNTP-AADLEVQQ 399
Query: 515 ADYLSGSEDPL 525
A + S L
Sbjct: 400 ATHREASPSTL 410
>gi|51479158 ataxin 1 [Homo sapiens]
Length = 815
Score = 53.5 bits (127), Expect = 2e-06
Identities = 94/371 (25%), Positives = 141/371 (38%), Gaps = 72/371 (19%)
Query: 178 PPQQPLAYP---KLQRQKLQNDIASPLPFPQGTHFPQHSQSFPTSSTYSSSVQGGGQGAH 234
PP P + P L +P+ Q H P H+ F SS YS G +
Sbjct: 89 PPSAPRSVPVATTLPAAYATPQPGTPVSPVQYAHLP-HTFQFIGSSQYS-----GTYASF 142
Query: 235 SYKSCTAPTAQPHDRPL-TASSSLAPGQRVQNLHAYQS-----GRLSY------DQQQQQ 282
PTA P + +A+ + P QR Q L AY + G LS +QQQQQ
Sbjct: 143 IPSQLIPPTANPVTSAVASAAGATTPSQRSQ-LEAYSTLLANMGSLSQTPGHKAEQQQQQ 201
Query: 283 QQQQQQQQQALQSRHHAQETLHYQNLAKYQHYGQQGQGYCQPDAAVRTPEQYYQTFSPSS 342
QQQQQQQ Q Q + Q+ Q+L++ G P + + Y S
Sbjct: 202 QQQQQQQHQHQQQQQQQQQQQQQQHLSR-------APGLITPGSPPPAQQNQYVHIS--- 251
Query: 343 SHSPARSVGRSPSYSSTPSPLMPNLENFPYSQQPLSTGAFPAGITDHSHFMPLLNPSPTD 402
S ++ GR+ S + P L P+ P++ L+ G P+
Sbjct: 252 --SSPQNTGRTASPPAIPVHLHPHQTMIPHT---LTLG------------------PPSQ 288
Query: 403 ATSSVDTQAGNCKPLQKDKLPENLLSDLSLQSLTALTSQVENI----SNTVQQLLLSKAA 458
+ P + K E+ ++Q+ L ++E + + L L KA
Sbjct: 289 VVMQYADSGSHFVPREATKKAESSRLQQAIQAKEVLNGEMEKSRRYGAPSSADLGLGKA- 347
Query: 459 VPQKKGVKNLVSRTPEQHKSQHCSPEGSGYSA-EPAGTPLSE---PPSSTPQSTHAEPQE 514
G K++ +H H SP S YS+ +P+G S P S+TP + E Q+
Sbjct: 348 -----GGKSVPHPYESRHVVVHPSP--SDYSSRDPSGVRASVMVLPNSNTP-AADLEVQQ 399
Query: 515 ADYLSGSEDPL 525
A + S L
Sbjct: 400 ATHREASPSTL 410
>gi|169167967 PREDICTED: hypothetical protein [Homo sapiens]
Length = 460
Score = 53.5 bits (127), Expect = 2e-06
Identities = 108/418 (25%), Positives = 151/418 (36%), Gaps = 67/418 (16%)
Query: 945 SLSHMKPGEEGPDGERAPGDSTTSDA-SLAQKPNKPAVPEAPIAKKEPVPRGKSLRSRRV 1003
+LS +PG D ER G S A +L P+ A++ P P G++
Sbjct: 18 TLSEARPG----DWERRAGSSLCGSAEALLLSPHVTGA-----AQRSPTP-GRA------ 61
Query: 1004 HRGLPEAEDSPCRAPVLPKDLLLPESCT-GPPQGQMEGAGAPGRGASEGLPRMC------ 1056
R P+ D R + L +S T GP +G + P GA LP +
Sbjct: 62 -RAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFGAGP-LPLVSRLGHAG 119
Query: 1057 ---------TRSLTALSEPRTPGPPGLTTTPAPPDKLGGKQRAAFKSGKRVGKPSPKAAS 1107
++A S P P P LTT PP K + + G R G+P A
Sbjct: 120 ERGSPGAGDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAPRPS---PGGRRGRPLGAARG 176
Query: 1108 SPSNPAALPVASDSSPMGSKT-KETDSPSTPGKDQRSMILRSRTKTQEIFHSKRRRPSEG 1166
+ NP P + P G ++ + TD+ S G R R R S+R RP G
Sbjct: 177 TGLNPGLSPRLQE--PRGHQSARRTDTASRAGWATRRAPSRRRNFGAP-RGSRRLRPDAG 233
Query: 1167 RLPNCRATK--------KLLDNSHLPATFKVSSSPQKEGRVSQRARVPKPGAGSKLSDRP 1218
+ P K ++LDN P S P G V + + AG+ LS R
Sbjct: 234 KFPEASGGKGQRAAGAERVLDNGRGPR----SRLPGLAGGV-EPPGWSRERAGAGLS-RD 287
Query: 1219 LHALKRKSAFMAPVPTKKRNLVLRSRS----SSSSNASGNGGDGKEERPEGSPTLFKRMS 1274
+ R ++ P + VL +S S + A+ G G P G TL R
Sbjct: 288 SPQVPRSGSWARPCREQGHPAVLALQSPAPPSLARAAARRRGPGGATEP-GFVTLAFRSR 346
Query: 1275 SPKKAKPTKGNGEPATKLPPPETPDACLKLA------SRAAFQGAMKTKVLPPRKGRG 1326
P P A + P P D L+ A S+ G K K P+ G G
Sbjct: 347 LPLLRSPGPEGTSDAARAPAPGLRDRDLRAAPPRPRPSQRPVSGLFKVKFFVPQSGPG 404
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.128 0.384
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 96,859,956
Number of Sequences: 37866
Number of extensions: 6049382
Number of successful extensions: 41439
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 160
Number of HSP's successfully gapped in prelim test: 1057
Number of HSP's that attempted gapping in prelim test: 27727
Number of HSP's gapped (non-prelim): 11035
length of query: 1906
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1789
effective length of database: 13,817,196
effective search space: 24718963644
effective search space used: 24718963644
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.