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Search of human proteins with 40807452
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40807452 peroxisome proliferator-activated receptor gamma,
coactivator-related 1 [Homo sapiens]
(1664 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40807452 peroxisome proliferator-activated receptor gamma, co... 3347 0.0
gi|7019499 peroxisome proliferator-activated receptor gamma, coa... 207 7e-53
gi|31543392 peroxisome proliferator-activated receptor gamma, co... 150 8e-36
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 138 4e-32
gi|163965366 nascent polypeptide-associated complex alpha subuni... 130 1e-29
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 114 6e-25
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 114 6e-25
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 114 6e-25
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 114 6e-25
gi|110349719 titin isoform N2-A [Homo sapiens] 107 1e-22
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 105 3e-22
gi|116284392 mucin 2 precursor [Homo sapiens] 105 4e-22
gi|47132519 Ras association and pleckstrin homology domains 1 is... 103 1e-21
gi|160707881 formin 2 [Homo sapiens] 100 2e-20
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 99 3e-20
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 97 1e-19
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 97 2e-19
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 97 2e-19
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 96 2e-19
gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 96 3e-19
gi|91982772 mucin 17 [Homo sapiens] 95 6e-19
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 90 2e-17
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 90 2e-17
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 90 2e-17
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 89 4e-17
gi|169205253 PREDICTED: hypothetical protein [Homo sapiens] 88 6e-17
gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 88 6e-17
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 85 5e-16
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 85 5e-16
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 85 7e-16
>gi|40807452 peroxisome proliferator-activated receptor gamma,
coactivator-related 1 [Homo sapiens]
Length = 1664
Score = 3347 bits (8678), Expect = 0.0
Identities = 1664/1664 (100%), Positives = 1664/1664 (100%)
Query: 1 MAARRGRRDGVAPPPSGGPGPDPGGGARGSGWGSRSQAPYGTLGAVSGGEQVLLHEEAGD 60
MAARRGRRDGVAPPPSGGPGPDPGGGARGSGWGSRSQAPYGTLGAVSGGEQVLLHEEAGD
Sbjct: 1 MAARRGRRDGVAPPPSGGPGPDPGGGARGSGWGSRSQAPYGTLGAVSGGEQVLLHEEAGD 60
Query: 61 SGFVSLSRLGPSLRDKDLEMEELMLQDETLLGTMQSYMDASLISLIEDFGSLGESRLSLE 120
SGFVSLSRLGPSLRDKDLEMEELMLQDETLLGTMQSYMDASLISLIEDFGSLGESRLSLE
Sbjct: 61 SGFVSLSRLGPSLRDKDLEMEELMLQDETLLGTMQSYMDASLISLIEDFGSLGESRLSLE 120
Query: 121 DQNEVSLLTALTEILDNADSENLSPFDSIPDSELLVSPREGSSLHKLLTLSRTPPERDLI 180
DQNEVSLLTALTEILDNADSENLSPFDSIPDSELLVSPREGSSLHKLLTLSRTPPERDLI
Sbjct: 121 DQNEVSLLTALTEILDNADSENLSPFDSIPDSELLVSPREGSSLHKLLTLSRTPPERDLI 180
Query: 181 TPVDPLGPSTGSSRGSGVEMSLPDPSWDFSPPSFLETSSPKLPSWRPPRSRPRWGQSPPP 240
TPVDPLGPSTGSSRGSGVEMSLPDPSWDFSPPSFLETSSPKLPSWRPPRSRPRWGQSPPP
Sbjct: 181 TPVDPLGPSTGSSRGSGVEMSLPDPSWDFSPPSFLETSSPKLPSWRPPRSRPRWGQSPPP 240
Query: 241 QQRSDGEEEEEVASFSGQILAGELDNCVSSIPDFPMHLACPEEEDKATAAEMAVPAAGDE 300
QQRSDGEEEEEVASFSGQILAGELDNCVSSIPDFPMHLACPEEEDKATAAEMAVPAAGDE
Sbjct: 241 QQRSDGEEEEEVASFSGQILAGELDNCVSSIPDFPMHLACPEEEDKATAAEMAVPAAGDE 300
Query: 301 SISSLSELVRAMHPYCLPNLTHLASLEDELQEQPDDLTLPEGCVVLEIVGQAATAGDDLE 360
SISSLSELVRAMHPYCLPNLTHLASLEDELQEQPDDLTLPEGCVVLEIVGQAATAGDDLE
Sbjct: 301 SISSLSELVRAMHPYCLPNLTHLASLEDELQEQPDDLTLPEGCVVLEIVGQAATAGDDLE 360
Query: 361 IPVVVRQVSPGPRPVLLDDSLETSSALQLLMPTLESETEAAVPKVTLCSEKEGLSLNSEE 420
IPVVVRQVSPGPRPVLLDDSLETSSALQLLMPTLESETEAAVPKVTLCSEKEGLSLNSEE
Sbjct: 361 IPVVVRQVSPGPRPVLLDDSLETSSALQLLMPTLESETEAAVPKVTLCSEKEGLSLNSEE 420
Query: 421 KLDSACLLKPREVVEPVVPKEPQNPPANAAPGSQRARKGRKKKSKEQPAACVEGYARRLR 480
KLDSACLLKPREVVEPVVPKEPQNPPANAAPGSQRARKGRKKKSKEQPAACVEGYARRLR
Sbjct: 421 KLDSACLLKPREVVEPVVPKEPQNPPANAAPGSQRARKGRKKKSKEQPAACVEGYARRLR 480
Query: 481 SSSRGQSTVGTEVTSQVDNLQKQPQEELQKESGPLQGKGKPRAWARAWAAALENSSPKNL 540
SSSRGQSTVGTEVTSQVDNLQKQPQEELQKESGPLQGKGKPRAWARAWAAALENSSPKNL
Sbjct: 481 SSSRGQSTVGTEVTSQVDNLQKQPQEELQKESGPLQGKGKPRAWARAWAAALENSSPKNL 540
Query: 541 ERSAGQSSPAKEGPLDLYPKLADTIQTNPIPTHLSLVDSAQASPMPVDSVEADPTAVGPV 600
ERSAGQSSPAKEGPLDLYPKLADTIQTNPIPTHLSLVDSAQASPMPVDSVEADPTAVGPV
Sbjct: 541 ERSAGQSSPAKEGPLDLYPKLADTIQTNPIPTHLSLVDSAQASPMPVDSVEADPTAVGPV 600
Query: 601 LAGPVPVDPGLVDLASTSSELVEPLPAEPVLINPVLADSAAVDPAVVPISDNLPPVDAVP 660
LAGPVPVDPGLVDLASTSSELVEPLPAEPVLINPVLADSAAVDPAVVPISDNLPPVDAVP
Sbjct: 601 LAGPVPVDPGLVDLASTSSELVEPLPAEPVLINPVLADSAAVDPAVVPISDNLPPVDAVP 660
Query: 661 SGPAPVDLALVDPVPNDLTPVDPVLVKSRPTDPRRGAVSSALGGSAPQLLVESESLDPPK 720
SGPAPVDLALVDPVPNDLTPVDPVLVKSRPTDPRRGAVSSALGGSAPQLLVESESLDPPK
Sbjct: 661 SGPAPVDLALVDPVPNDLTPVDPVLVKSRPTDPRRGAVSSALGGSAPQLLVESESLDPPK 720
Query: 721 TIIPEVKEVVDSLKIESGTSATTHEARPRPLSLSEYRRRRQQRQAETEERSPQPPTGKWP 780
TIIPEVKEVVDSLKIESGTSATTHEARPRPLSLSEYRRRRQQRQAETEERSPQPPTGKWP
Sbjct: 721 TIIPEVKEVVDSLKIESGTSATTHEARPRPLSLSEYRRRRQQRQAETEERSPQPPTGKWP 780
Query: 781 SLPETPTGLADIPCLVIPPAPAKKTALQRSPETPLEICLVPVGPSPASPSPEPPVSKPVA 840
SLPETPTGLADIPCLVIPPAPAKKTALQRSPETPLEICLVPVGPSPASPSPEPPVSKPVA
Sbjct: 781 SLPETPTGLADIPCLVIPPAPAKKTALQRSPETPLEICLVPVGPSPASPSPEPPVSKPVA 840
Query: 841 SSPTEQVPSQEMPLLARPSPPVQSVSPAVPTPPSMSAALPFPAGGLGMPPSLPPPPLQPP 900
SSPTEQVPSQEMPLLARPSPPVQSVSPAVPTPPSMSAALPFPAGGLGMPPSLPPPPLQPP
Sbjct: 841 SSPTEQVPSQEMPLLARPSPPVQSVSPAVPTPPSMSAALPFPAGGLGMPPSLPPPPLQPP 900
Query: 901 SLPLSMGPVLPDPFTHYAPLPSWPCYPHVSPSGYPCLPPPPTVPLVSGTPGAYAVPPTCS 960
SLPLSMGPVLPDPFTHYAPLPSWPCYPHVSPSGYPCLPPPPTVPLVSGTPGAYAVPPTCS
Sbjct: 901 SLPLSMGPVLPDPFTHYAPLPSWPCYPHVSPSGYPCLPPPPTVPLVSGTPGAYAVPPTCS 960
Query: 961 VPWAPPPAPVSPYSSTCTYGPLGWGPGPQHAPFWSTVPPPPLPPASIGRAVPQPKMESRG 1020
VPWAPPPAPVSPYSSTCTYGPLGWGPGPQHAPFWSTVPPPPLPPASIGRAVPQPKMESRG
Sbjct: 961 VPWAPPPAPVSPYSSTCTYGPLGWGPGPQHAPFWSTVPPPPLPPASIGRAVPQPKMESRG 1020
Query: 1021 TPAGPPENVLPLSMAPPLSLGLPGHGAPQTEPTKVEVKPVPASPHPKHKVSALVQSPQMK 1080
TPAGPPENVLPLSMAPPLSLGLPGHGAPQTEPTKVEVKPVPASPHPKHKVSALVQSPQMK
Sbjct: 1021 TPAGPPENVLPLSMAPPLSLGLPGHGAPQTEPTKVEVKPVPASPHPKHKVSALVQSPQMK 1080
Query: 1081 ALACVSAEGVTVEEPASERLKPETQETRPREKPPLPATKAVPTPRQSTVPKLPAVHPARL 1140
ALACVSAEGVTVEEPASERLKPETQETRPREKPPLPATKAVPTPRQSTVPKLPAVHPARL
Sbjct: 1081 ALACVSAEGVTVEEPASERLKPETQETRPREKPPLPATKAVPTPRQSTVPKLPAVHPARL 1140
Query: 1141 RKLSFLPTPRTQGSEDVVQAFISEIGIEASDLSSLLEQFEKSEAKKECPPPAPADSLAVG 1200
RKLSFLPTPRTQGSEDVVQAFISEIGIEASDLSSLLEQFEKSEAKKECPPPAPADSLAVG
Sbjct: 1141 RKLSFLPTPRTQGSEDVVQAFISEIGIEASDLSSLLEQFEKSEAKKECPPPAPADSLAVG 1200
Query: 1201 NSGGVDIPQEKRPLDRLQAPELANVAGLTPPATPPHQLWKPLAAVSLLAKAKSPKSTAQE 1260
NSGGVDIPQEKRPLDRLQAPELANVAGLTPPATPPHQLWKPLAAVSLLAKAKSPKSTAQE
Sbjct: 1201 NSGGVDIPQEKRPLDRLQAPELANVAGLTPPATPPHQLWKPLAAVSLLAKAKSPKSTAQE 1260
Query: 1261 GTLKPEGVTEAKHPAAVRLQEGVHGPSRVHVGSGDHDYCVRSRTPPKKMPALVIPEVGSR 1320
GTLKPEGVTEAKHPAAVRLQEGVHGPSRVHVGSGDHDYCVRSRTPPKKMPALVIPEVGSR
Sbjct: 1261 GTLKPEGVTEAKHPAAVRLQEGVHGPSRVHVGSGDHDYCVRSRTPPKKMPALVIPEVGSR 1320
Query: 1321 WNVKRHQDITIKPVLSLGPAAPPPPCIAASREPLDHRTSSEQADPSAPCLAPSSLLSPEA 1380
WNVKRHQDITIKPVLSLGPAAPPPPCIAASREPLDHRTSSEQADPSAPCLAPSSLLSPEA
Sbjct: 1321 WNVKRHQDITIKPVLSLGPAAPPPPCIAASREPLDHRTSSEQADPSAPCLAPSSLLSPEA 1380
Query: 1381 SPCRNDMNTRTPPEPSAKQRSMRCYRKACRSASPSSQGWQGRRGRNSRSVSSGSNRTSEA 1440
SPCRNDMNTRTPPEPSAKQRSMRCYRKACRSASPSSQGWQGRRGRNSRSVSSGSNRTSEA
Sbjct: 1381 SPCRNDMNTRTPPEPSAKQRSMRCYRKACRSASPSSQGWQGRRGRNSRSVSSGSNRTSEA 1440
Query: 1441 SSSSSSSSSSSRSRSRSLSPPHKRWRRSSCSSSGRSRRCSSSSSSSSSSSSSSSSSSSSR 1500
SSSSSSSSSSSRSRSRSLSPPHKRWRRSSCSSSGRSRRCSSSSSSSSSSSSSSSSSSSSR
Sbjct: 1441 SSSSSSSSSSSRSRSRSLSPPHKRWRRSSCSSSGRSRRCSSSSSSSSSSSSSSSSSSSSR 1500
Query: 1501 SRSRSPSPRRRSDRRRRYSSYRSHDHYQRQRVLQKERAIEERRVVFIGKIPGRMTRSELK 1560
SRSRSPSPRRRSDRRRRYSSYRSHDHYQRQRVLQKERAIEERRVVFIGKIPGRMTRSELK
Sbjct: 1501 SRSRSPSPRRRSDRRRRYSSYRSHDHYQRQRVLQKERAIEERRVVFIGKIPGRMTRSELK 1560
Query: 1561 QRFSVFGEIEECTIHFRVQGDNYGFVTYRYAEEAFAAIESGHKLRQADEQPFDLCFGGRR 1620
QRFSVFGEIEECTIHFRVQGDNYGFVTYRYAEEAFAAIESGHKLRQADEQPFDLCFGGRR
Sbjct: 1561 QRFSVFGEIEECTIHFRVQGDNYGFVTYRYAEEAFAAIESGHKLRQADEQPFDLCFGGRR 1620
Query: 1621 QFCKRSYSDLDSNREDFDPAPVKSKFDSLDFDTLLKQAQKNLRR 1664
QFCKRSYSDLDSNREDFDPAPVKSKFDSLDFDTLLKQAQKNLRR
Sbjct: 1621 QFCKRSYSDLDSNREDFDPAPVKSKFDSLDFDTLLKQAQKNLRR 1664
>gi|7019499 peroxisome proliferator-activated receptor gamma,
coactivator 1 alpha [Homo sapiens]
Length = 798
Score = 207 bits (527), Expect = 7e-53
Identities = 118/235 (50%), Positives = 152/235 (64%), Gaps = 18/235 (7%)
Query: 1445 SSSSSSSRSRSRSLSPPHKRWRRSSCSSSGRSRRCSSSSSSSSSSSSSSSSSSSSRSRSR 1504
S S S SR RS S SP + R R S S SR C SS + +S RSRSR
Sbjct: 567 SRSRSFSRHRSCSRSP-YSRSRSRSPGSRSSSRSCYYYESSHYRHRTHRNSPLYVRSRSR 625
Query: 1505 SPSPRR---------------RSDRRRRYSSYRSHDHYQRQRVLQKERAIEERRVVFIGK 1549
SP RR R + RR Y S QR+R Q+++AIEERRV+++GK
Sbjct: 626 SPYSRRPRYDSYEEYQHERLKREEYRREYEKRESERAKQRER--QRQKAIEERRVIYVGK 683
Query: 1550 IPGRMTRSELKQRFSVFGEIEECTIHFRVQGDNYGFVTYRYAEEAFAAIESGHKLRQADE 1609
I TR+EL+ RF VFGEIEECT++ R GD+YGF+TYRY +AFAA+E+G+ LR+++E
Sbjct: 684 IRPDTTRTELRDRFEVFGEIEECTVNLRDDGDSYGFITYRYTCDAFAALENGYTLRRSNE 743
Query: 1610 QPFDLCFGGRRQFCKRSYSDLDSNREDFDPAPVKSKFDSLDFDTLLKQAQKNLRR 1664
F+L F GR+QF K +Y+DLDSN +DFDPA KSK+DSLDFD+LLK+AQ++LRR
Sbjct: 744 TDFELYFCGRKQFFKSNYADLDSNSDDFDPASTKSKYDSLDFDSLLKEAQRSLRR 798
Score = 40.0 bits (92), Expect = 0.019
Identities = 34/121 (28%), Positives = 50/121 (41%), Gaps = 24/121 (19%)
Query: 1208 PQEKRPLDRLQAPELANVAGLTPPATPPHQLWK--PLAAVSLLAK---------AKSPKS 1256
P E + ++R + EL+ AGLTPP TPPH+ + P A L +K P+
Sbjct: 274 PFENKTIERTLSVELSGTAGLTPPTTPPHKANQDNPFRASPKLKSSCKTVVPPPSKKPRY 333
Query: 1257 TAQEGTLKPEGVTEAKHPAAVRLQ-------EGVHGPSRVHVGS----GDHDYC--VRSR 1303
+ GT + + + Q G H + S GDHDYC + S+
Sbjct: 334 SESSGTQGNNSTKKGPEQSELYAQLSKSSVLTGGHEERKTKRPSLRLFGDHDYCQSINSK 393
Query: 1304 T 1304
T
Sbjct: 394 T 394
Score = 35.4 bits (80), Expect = 0.47
Identities = 26/89 (29%), Positives = 45/89 (50%), Gaps = 3/89 (3%)
Query: 69 LGPSLRDKDL-EMEELMLQDETLLGTMQSYMDASLISLIEDFGSLGESRLSLEDQNEVSL 127
L P L + DL E++ L ++ LG ++ D S I + ++++NE +L
Sbjct: 29 LCPDLPELDLSELDVNDLDTDSFLGGLKWCSDQSEIISNQYNNEPSNIFEKIDEENEANL 88
Query: 128 LTALTEILDN--ADSENLSPFDSIPDSEL 154
L LTE LD+ D + L FD++ D ++
Sbjct: 89 LAVLTETLDSLPVDEDGLPSFDALTDGDV 117
>gi|31543392 peroxisome proliferator-activated receptor gamma,
coactivator 1 beta [Homo sapiens]
Length = 1023
Score = 150 bits (380), Expect = 8e-36
Identities = 264/1047 (25%), Positives = 369/1047 (35%), Gaps = 186/1047 (17%)
Query: 677 DLTPVDPVLVKSRPTDPRRGAVSSALGGSAPQLLVESESLDPPKTIIPEVKEVVDSLKIE 736
D P D V + + P A+S AP S + + P PEV E+ K+
Sbjct: 101 DDIPEDDVGLAAFPALDGGDALSCTSASPAPSSAPPSPAPEKPSAPAPEVDELSLLQKLL 160
Query: 737 SGTSATTHEARP-------RPLSLSEYRRRRQQRQAETEERSPQPPTGKWPSLPETPTGL 789
TS T + R L +R + T+++ + S E L
Sbjct: 161 LATSYPTSSSDTQKEGTAWRQAGLRSKSQRPCVKADSTQDKKAPMMQSQSRSCTELHKHL 220
Query: 790 ADI-----------PCLVIPPAPAKKTALQRSPETPLEICLVPVGPSPASPSPEPPVSKP 838
PCL P PAK+ + P E C P P+PASP + +
Sbjct: 221 TSAQCCLQDRGLQPPCLQSPRLPAKED------KEPGEDCPSPQ-PAPASPQDSLALGRA 273
Query: 839 VASSPTEQVPSQEMPLLARPSPPVQSVSPAVPTPPSMSAALPFPAGGLGMPPSLPPPPLQ 898
+P Q Q M L R + LP +PP P P +
Sbjct: 274 DPGAPVSQEDMQAMVQLIRYMH---------------TYCLPQRK----LPPQTPEPLPK 314
Query: 899 PPSLPLSMGPVLPDPFTHYAPLPSWPCYP---HVSPSGYPCLPPPP----TVPLVSGTPG 951
S P V P++ + SW + + C P T S TP
Sbjct: 315 ACSNPSQQ--VRSRPWSRHHSKASWAEFSILRELLAQDVLCDVSKPYRLATPVYASLTPR 372
Query: 952 AYAVPPTCSVPWAPPPAPVSPYSSTCTYGPLGWGPGPQHAPFWSTVPPPPLPPASIGRAV 1011
+ PP S A P P S P GP P P V PA + +
Sbjct: 373 SRPRPPKDSQ--ASPGRPSSVEEVRIAASPKSTGPRPSLRPLRLEVKREVRRPARLQQQE 430
Query: 1012 PQPKMESRGTPAGPPENVLPLSMAPPLSLGLPGHGAPQTE-PTKVEVKPVPASPHPKHKV 1070
+ + E E PG G P T+ K+E P
Sbjct: 431 EEDEEEEEEEEEEEKEE------EEEWGRKRPGRGLPWTKLGRKLESSVCPVR------- 477
Query: 1071 SALVQSPQMKALACVSAEGVTVEEPASERLKPETQETRPREKPPLPATKAVPTPRQSTVP 1130
S RL PE PL VP+ Q +P
Sbjct: 478 -------------------------RSRRLNPELGPWLTFADEPL-----VPSEPQGALP 507
Query: 1131 KL---PAVHPARLRKLSFLPTPRTQGSEDVVQAFISEIGIEASDLSSLLEQFEKSEAKKE 1187
L P + R+L PT G + + +E+ S + E
Sbjct: 508 SLCLAPKAYDVE-RELGS-PTDEDSGQDQQLLRGPQIPALESPCESGCGDMDEDPS---- 561
Query: 1188 CPPPAPADS-----LAVGNSGGVDIPQEKRPLDRLQAPELANVAGLTPPATPP------- 1235
CP P DS LA+ S D K+ ++ EL AGLTPP TPP
Sbjct: 562 CPQLPPRDSPRCLMLALSQS---DPTFGKKSFEQTLTVELCGTAGLTPPTTPPYKPTEED 618
Query: 1236 -------HQLWKPLA-------AVSLLAKAKSPKSTAQEGTLKPEGVTEAKHPAAVRLQE 1281
H L K +A +SL A + ++ + E ++ +H A +
Sbjct: 619 PFKPDIKHSLGKEIALSLPSPEGLSLKATPGAAHKLPKKHPERSELLSHLRHATAQPASQ 678
Query: 1282 GVHGPSRVHVGS-GDHDYCVRSRTPPKKMPALVIPEVGSRWNVKRHQDITIKPVLSLGPA 1340
G R S GDHDYC R ++ +V W + ++ G
Sbjct: 679 A--GQKRPFSCSFGDHDYCQVLRP-----EGVLQRKVLRSW---EPSGVHLEDWPQQG-- 726
Query: 1341 APPPPCIAASREPLDHRTSSEQADPSAPCLAPSSLLSPEASPCRNDMNTRTPPEPSAKQR 1400
AP A RE + R+ A P L + + + T E A +
Sbjct: 727 APWAEAQAPGRE--EDRSCDAGAPPKDSTLLRDHEIRASLTKHFGLLETALEEEDLASCK 784
Query: 1401 SMRCYRKACRSASPSSQGWQGRRGRNS----RSVSSGSNRTSEASSSSSSSSSSSRSRSR 1456
S Y +S SS G +S G + S S +
Sbjct: 785 SPE-YDTVFEDSSSSS-------GESSFLPEEEEEEGEEEEEDDEEEDSGVSPTCSDHCP 836
Query: 1457 SLSPPHKRWRRSSCSSSGRSRRCSSSSSSSSSSSSSSSSSSSSRSRSRSPSPRRRSDRRR 1516
SPP K R CS R SSS SS S S ++ + R SR P R R
Sbjct: 837 YQSPPSKA-NRQLCS------RSRSSSGSSPCHSWSPATRRNFRCESRGPCSDRTPSIR- 888
Query: 1517 RYSSYRSHDHYQRQRVLQKERAIEERRVVFIGKIPGRMTRSELKQRFSVFGEIEECTIHF 1576
H +++R E+AI E RVV+I + M+ ELK+RF VFGEIEEC +
Sbjct: 889 ---------HARKRR----EKAIGEGRVVYIQNLSSDMSSRELKRRFEVFGEIEECEVLT 935
Query: 1577 R-VQGDNYGFVTYRYAEEAFAAIESGHKLRQADEQPFDLCFGGRRQFCKRSYSDLDSNRE 1635
R +G+ YGF+TYR +E A ++ G LR+ +E F L +GG R FC Y+D DSN E
Sbjct: 936 RNRRGEKYGFITYRCSEHAALSLTKGAALRKRNEPSFQLSYGGLRHFCWPRYTDYDSNSE 995
Query: 1636 DFDPAPVKSKFDSLDFDTLLKQAQKNL 1662
+ PA KSK++++DFD+LLK+AQ++L
Sbjct: 996 EALPASGKSKYEAMDFDSLLKEAQQSL 1022
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 138 bits (348), Expect = 4e-32
Identities = 211/827 (25%), Positives = 307/827 (37%), Gaps = 125/827 (15%)
Query: 447 ANAAPGSQRARKG-RKKKSKEQPAACVEGYARRLRSSSRGQSTVGTEVTSQVDNLQKQPQ 505
A AP G R+ S P ARR R++ +++ + P+
Sbjct: 147 ATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPR 206
Query: 506 EELQKESGPLQGKGKPRAWARAWAAA-LENSSPKNLERSAGQ-SSPAKEGPLDLYPKLAD 563
+ + S + P A R A L+ + ++L SA SSPA+ GP A
Sbjct: 207 KSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAP 266
Query: 564 TIQTNPIPTHLSLVDSAQASPMPVDSVEADPTAVGPVLAGPV-----------PVDPGLV 612
+ P P L + Q +P D+ A+GP+ + P+ PV P
Sbjct: 267 AHPSQPKPKGLQALRPPQVTPPRKDAA----PALGPLSSSPLATPSPSGTKARPVPP--P 320
Query: 613 DLASTSSELVEPLPAEPVLINPVLADSAAVDPAVVPISDNLPPVDAVPSGPAPVDLALVD 672
D A+T L LP P L P+ A P+ P LP A P AP +
Sbjct: 321 DNAAT--PLPATLPPSPPLATPL--PLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPP 376
Query: 673 -PVPNDLTPVDPVLVKSRPTDPRRGAVSSALGGSAPQLLVESESLDPPKTIIPEVKEVVD 731
P L + P+ V T P A S L +
Sbjct: 377 MQAPPSLQTIPPIQVPHSLTSPSLQAPPSPL--------------------------ALS 410
Query: 732 SLKIESGTSATTHEARPRPLSLSEYRRRRQQRQAETEERSPQPPTGKWPSLPETPTGLAD 791
SL+ + + T +A L++S RQ + SP P P P L+
Sbjct: 411 SLQATTSLGSPTLQATHSFLTMS-------PRQTQASLTSPSRPASTPPDSPPLQAPLS- 462
Query: 792 IPCLVIPPAPAKKTALQR--SP-ETPLEICLVPVGPSPASPSPEPPVSK----PVASSPT 844
+P +P +T+L SP +PL I + S AS SP+ P+S P+ + +
Sbjct: 463 -----LPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSS 517
Query: 845 EQVPSQEMPLLARPSPPVQSVSPAVPTPPSMSAALPFPAGGLGMPPSLPPPPLQPPSLPL 904
PS + P + +PP++++ P++ PP +A+ P L PP P PLQ P PL
Sbjct: 518 LAPPSLQTPPASLTTPPLENL-PSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPL 576
Query: 905 SMGPVLPDPFTHYAPLPSWPCYPHVSPSGYPCLPPPPTVPLVSGTPGA---YAVPPTCSV 961
+ P P + P P P P ++ LP PP PL + P A A+PP +
Sbjct: 577 TTPPP-ETPSSIATPPPQAP--PALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAP 633
Query: 962 PWAPPPAPVSPYSSTCTYGPLGWGPGPQHAPFWSTVPPPPLPPASIGRAVP-QPKMESRG 1020
P P P+SP ++ P APF PPP PP + P P +
Sbjct: 634 PSPPASPPLSPLATPSPQAPNALAVHLLQAPF----SPPPSPPVQAPFSPPASPPVSPSA 689
Query: 1021 TP--------AGPPENVLPLSMA-PPLSLGLPGHGAPQTEPTKVEVKP--VPASPHPKHK 1069
TP A PP V P A PP+S P P P + P VP SP
Sbjct: 690 TPPSQAPPSLAAPPLQVPPSPPASPPMS---PSATPPPQAPPPLAAPPLQVPPSPPASPP 746
Query: 1070 VS-ALVQSPQMKALACVSAEGVTVEEPASERLKPETQETRPREKPPLPATKAVPTPRQST 1128
+S + P++ L V PAS + P KPP A A+ TP
Sbjct: 747 MSPSATPPPRVPPLLAAPPLQVPPSPPASLPMS-------PLAKPPPQAPPALATPPLQA 799
Query: 1129 VPKLPAVHPARL-------RKLSFLPTPRTQGSEDVVQAFISEIGIEASDLSSLLEQFEK 1181
+P PA P + +S L TP Q + V+ A + ++ +L
Sbjct: 800 LPSPPASFPGQAPFSPSASLPMSPLATPPPQ-APPVLAAPLLQVPPSPPASPTL------ 852
Query: 1182 SEAKKECPPPAPADS-----LAVGNSGGVDIPQEKRPLDRLQAPELA 1223
+A + P P P S L + + G P + P L P+LA
Sbjct: 853 -QAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLA 898
Score = 97.4 bits (241), Expect = 1e-19
Identities = 205/865 (23%), Positives = 294/865 (33%), Gaps = 113/865 (13%)
Query: 695 RGAVSSALGGSAPQLLVESESLDP-PKTIIPEVKEVVDSLKIESGTSATTHEARPRPLSL 753
RG + A SA ++ P P T P + + E G ARPRP +
Sbjct: 144 RGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPT- 202
Query: 754 SEYRRRRQQRQAETEERSPQPPTGKWPSLPETPTGLADIPCLVIPPAPAKKTALQRSPET 813
E R+ +E P P + PS GL + + ++ RS +
Sbjct: 203 -EGPRKSVSSASEHSTTEPSPAARRRPS---AGGGLQRPASRSLSSSATPLSSPARSGPS 258
Query: 814 PLEICLVPVGPSPASPSPEPPVSKPVASSPTEQVPSQEMPLLARP-SPPVQSVSPAVPTP 872
P PS P + P + P + PL + P + P S + A P P
Sbjct: 259 ARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVP 318
Query: 873 PSMSAALPFPAGGLGMPPSLPPPPLQPPSLPLSMGPVLPDPFTHYAPLPSWPCYPHVSPS 932
P +AA P PA +LPP P P + PL + P P LPS P P PS
Sbjct: 319 PPDNAATPLPA-------TLPPSP--PLATPLPLAPPSPSAPPSLQTLPSPPATP---PS 366
Query: 933 GYPCLPPPPTVPLVSGTPGAYAVPP--------TCSVPWAPPPAPVSPYSSTCTYGPLGW 984
PP T P + P +PP + S+ P P +S +T + G
Sbjct: 367 Q---APPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLG---- 419
Query: 985 GPGPQHAPFWSTVPPPPLPPASIGRAVPQPKMESRGTPAGPP-ENVLPLSMAPPLSLGLP 1043
P Q + T + P ++ P + P PP + L L +PPL L
Sbjct: 420 SPTLQATHSFLT-----MSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLS 474
Query: 1044 GHGAPQTEPTKVEVKPVPASPHPKHKVSALV-QSPQ--MKALACVSAEGVTVEEPASERL 1100
+P + P + HP +S+L SPQ + +L E + P S +
Sbjct: 475 PAVSPLSSPLTI---------HPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQT 525
Query: 1101 KPETQETRPREK------PPLPATKAVPTPRQSTVPKLPAVHPARLRKLSFLPTPRTQGS 1154
P + T P E PPL A T P PA P L P+P T
Sbjct: 526 PPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCP-----LQAPPSPLTTPP 580
Query: 1155 EDVVQAFISEIGIEASDLSSLLEQFEKSE--AKKECPPPAPADSLAVGNSGGVDIPQEKR 1212
+ + + L+S Q S + PPP LA+ P
Sbjct: 581 PETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASP 640
Query: 1213 PLDRL-----QAPELANV----AGLTPPATPPHQLWKPLAAVSLLAKAKSPKSTAQEGTL 1263
PL L QAP V A +PP +PP Q A ++ + +P S A
Sbjct: 641 PLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLA 700
Query: 1264 KPEGVTEAKHPAAVRLQEGVHGPS-----------RVHVGSGDHDYCVRSRTPPKKMPAL 1312
P PA+ + P +V S TPP ++P L
Sbjct: 701 APPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPL 760
Query: 1313 VIPEVGSRWNVKRHQDITIKP----VLSLGPAAPPPPCIAASREPLDHRTSSEQADPSAP 1368
+ + + P L + P A PPP + P T QA PS P
Sbjct: 761 LAA-----------PPLQVPPSPPASLPMSPLAKPPP-----QAPPALATPPLQALPSPP 804
Query: 1369 CLAPSSL-LSPEASPCRNDMNTRTPPEPSAKQRSMRCYRKACRSASPSSQGWQGRRGRNS 1427
P SP AS + + T P P + ASP+ Q RR
Sbjct: 805 ASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPL-LQVPPSPPASPTLQA--PRRPPTP 861
Query: 1428 RSVSSGSNRTSEASSSSSSSSSSSRSRSRSLSPPHKRWRRSSCSSSGRSRRCSSSSSSSS 1487
+S S + + SRS S +LS P SS +S+ R S
Sbjct: 862 GPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGG 921
Query: 1488 SSSS----SSSSSSSSRSRSRSPSP 1508
+++S + ++ + SR P+P
Sbjct: 922 AAASPPPDAELAACHPAAWSRGPAP 946
Score = 92.8 bits (229), Expect = 2e-18
Identities = 128/467 (27%), Positives = 164/467 (35%), Gaps = 51/467 (10%)
Query: 569 PIPTHLSLVDSAQASPMPV--DSVEADPTAVGPVLAGPVPVDPGLVDLASTSSELVEPLP 626
P P L S +P P S+ P P LA P L S + PL
Sbjct: 564 PAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASP--------PLQGLPSPPLSPLA 615
Query: 627 AEPVLINPVLADSAAVDPAVVPISDNLPPVDAVPSGPAPVDLAL-VDPVPNDLTPVDPVL 685
P P LA P P S L P+ A PS AP LA+ + P P PV
Sbjct: 616 TPPPQAPPXLALPPLQAPPSPPASPPLSPL-ATPSPQAPNALAVHLLQAPFSPPPSPPVQ 674
Query: 686 VK-SRPTDPRRGAVSSALGGSAPQLLVESESLDPPKTIIPEVKEVVDSLKIESGTSATTH 744
S P P ++ + P L + P P + SAT
Sbjct: 675 APFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSP-----------SATPP 723
Query: 745 EARPRPLSLSEYRRRRQQRQAETEERSPQPPTGKWPSLPETPTGLADIPCLVIPPAPAKK 804
P PL+ + + S PP P L P + P +P +P K
Sbjct: 724 PQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAK 783
Query: 805 TALQRSPET---PLEICLVPV----GPSPASPSPEPPVSKPVASSPTEQVPSQEMPLL-A 856
Q P PL+ P G +P SPS P+S P+A+ P + P PLL
Sbjct: 784 PPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMS-PLATPPPQAPPVLAAPLLQV 842
Query: 857 RPSPPVQSV--SPAVPTPPSMSAALPFPAGGLGMPPSLPPPPLQPPSLPLSMGPVLPDPF 914
PSPP +P P P ++ P L + P PPPP + PS LS GP L
Sbjct: 843 PPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLS-GPDLAGHS 901
Query: 915 THYAPLPSWPCYPHVSPSGYPCLPPPPTVPLVSGTPGAY----AVP------PTCSVPWA 964
+ P P G PPP L + P A+ A P P +PW
Sbjct: 902 SSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWP 961
Query: 965 PPPAPVSPYSSTCTYGPLGWGPGPQHA-PFWSTVPPPPLPPASIGRA 1010
P P S CT + GP+ A P + P P P S G+A
Sbjct: 962 PATGPGSA-DGLCT---IYETEGPESATPAPGALDPGPSPGTSGGKA 1004
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 130 bits (326), Expect = 1e-29
Identities = 257/1142 (22%), Positives = 362/1142 (31%), Gaps = 172/1142 (15%)
Query: 433 VVEPVVPKE---PQNPPANAAPGSQRARKGRKKKSKEQPAAC------VEGYARRLRSSS 483
V+ P +PK P PPA PG+++ G S P A E +SS
Sbjct: 725 VLAPEIPKSVPSPSLPPAGTPPGTKKV-DGISHTSALAPVASSPKECPTEDSGASATASS 783
Query: 484 RGQSTVGTEVTSQVDNLQKQPQEELQKESGPLQGKGKPRAWARAWAAALENSS-PKN-LE 541
+G T + S + + PQ + G P + + +E S P+N L
Sbjct: 784 KGTLTYLADSPSPL-GVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLS 842
Query: 542 RSAGQSSPAK-EGPLDLYPKLADTIQT-----------------NPIPTHLSLVDSAQAS 583
+ SPA P PK A T P +L A+
Sbjct: 843 FQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPAT 902
Query: 584 PMPVDSVEADPTAVGPVLAGPVPVDPGLVDLASTSSELVEPLPAEPVLINPVLADS---A 640
P P + T+ P A P G+ S P P S A
Sbjct: 903 PAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWA 962
Query: 641 AVDPAVVPISDNLPPVDAVPSGPAPVDLALVDPVPNDLTPVDPVLVKSRPTDPRRGAVSS 700
PA P S P P G AP A P P P P K PT P
Sbjct: 963 PTPPAATPPSPKGGPATPSPKG-APTPPAATPPSPKG-GPATPS-PKGAPTPP--AVTPP 1017
Query: 701 ALGGSAPQLLVESESLDPPKTIIPEVKEVVDSLKIESGTSATTHEARPRPLSLSEYRRRR 760
+ GS + PP P K + + G T P P +
Sbjct: 1018 SPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSP---------K 1068
Query: 761 QQRQAETEERSPQPPTGKWPSL---PETPTGL-ADIPCLVIPPAPAKKTALQRSPETPLE 816
+ + +P PP PS P TP+ A +P PP+P A P
Sbjct: 1069 GGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTT 1128
Query: 817 ICLVPVGPSPASPSPEPPVSKPVASSPTEQVPSQEMPLLARPSPPVQSVSPAVPTPPSMS 876
P P +P P K ++P PS + L P + A P P
Sbjct: 1129 PAATPPSPKGGLATPPP---KGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGG 1185
Query: 877 AALPFPAGGLGMPPSLPPPPL------QPPSLPLSMGPVLPDPFTHYAP-----LPSWPC 925
A P P G P + PP P P P + P P A P+ P
Sbjct: 1186 LATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPA 1245
Query: 926 YPHVSPSGYPCLPPPPTVPLVSGTPGAYAVPPTCSVPWAPPPAPVSPYSSTCTYGPLGWG 985
SP G P PPP P TP A A PP+ A PP +P + T
Sbjct: 1246 ATPPSPKGGPATPPPKGAP----TPPA-ATPPSLKGGLATPPHKGAPNPAVVT------P 1294
Query: 986 PGPQHAPFWSTVPPPPLPPASIGRAVPQPKMESRGTPAGPPENVLPL--SMAPPLSLGLP 1043
P P+ P S P PPA+ P PK G+P PP P ++ PP G P
Sbjct: 1295 PSPKGGPATSPPKGAPTPPAA---TPPSPK----GSPGTPPPKGAPTPPAVTPPSPKGTP 1347
Query: 1044 --------GHGAPQTEPTKVEVKPVPASPHPKHKVSALVQSPQMKALACVSAEGVTVEEP 1095
G P T +K P P + P HK + P K G + P
Sbjct: 1348 TLPATTPSSKGGPTTPSSKEG--PTPPAATPSHKGGPAMTPPSPK-------RGPAIPSP 1398
Query: 1096 ASERLKPETQETRPREKPPLPATK-AVPTPRQSTVPKLPAVHPARLRKLSFLPTPRTQGS 1154
+ P P++ P P T+ TP + + PAV P L+K P+
Sbjct: 1399 KGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTP-PAVTPVSLKKAPATSAPK---- 1453
Query: 1155 EDVVQAFISEIGIEASDLSSLLEQFEKSEAKKECPPPAPADSLAVGNSGGVDIPQEKRPL 1214
G A+ S PPAP +S P P+
Sbjct: 1454 -----------GGPATPSSKGDPTLPAVTPPSPKEPPAPKQ--VATSSSPKKAPATPAPM 1500
Query: 1215 DRLQAPELANVAGLTPPATPPHQLWKPLAAVSLLAKAKSPKSTAQEGTLKPEGVTEAKHP 1274
P + + PATP + P+A + L K+P + A + L P +T
Sbjct: 1501 GAPTLPAVIPSSPKEVPATPSSRR-DPIAPTATLLSKKTPATLAPKEALIPPAMTV---- 1555
Query: 1275 AAVRLQEGVHGPSRVHVGSGDHDYCVRSRTPPKKMPALVIPEVGSRWNVKRHQDITIKPV 1334
PS PKK PA+ P+ +
Sbjct: 1556 -----------PS------------------PKKTPAIPTPKEAPATPSSKEASSPPAVT 1586
Query: 1335 LSLGPAAPPPPCIAASREPLDHRTSSEQADPSAPCLAPSSLLSPEASPCRNDMNTRTPPE 1394
S AP P + P + S + P+ P + P S A+P T P
Sbjct: 1587 PSTYKGAPSPKELLI---PPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVT 1643
Query: 1395 PSA------KQRSMRCYRKACRSASPSSQGWQGRRGRNS-RSVSSGSNRTSEASSSSSSS 1447
PS+ S+ C K + +S+G ++G + + V S ++ +
Sbjct: 1644 PSSLKDSPTSPASVTC--KMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTR 1701
Query: 1448 SSSSRSRSRSLSPPHKRWRRSSCSSSGRSRRCSSSSSSSSSSSSSSSSSSSSRSRSRSPS 1507
+S + SPP S+ S+ S+ + + SS +++ + S S
Sbjct: 1702 KGPQTKKSSATSPP----ICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHS 1757
Query: 1508 PR 1509
P+
Sbjct: 1758 PK 1759
Score = 125 bits (314), Expect = 3e-28
Identities = 234/970 (24%), Positives = 332/970 (34%), Gaps = 123/970 (12%)
Query: 494 TSQVDNLQKQPQEELQKES-GPLQGKGKPRAWARAWAAALENSSPKNLERSAGQSSPAKE 552
TS + P+ L K+S G GKP A + + L +S ++ ++ + P
Sbjct: 576 TSSSPEIPLSPEATLAKKSLGEPLPIGKP---ASSMTSPLGVNSSASVIKTDSYAGPDSA 632
Query: 553 GPLDLYPKLADTIQTNPIPTHLSLVDSAQASPMPVDSVEADPTAVGPVLAGPV------- 605
GPL + T+ P+ + D A +P T P L G V
Sbjct: 633 GPLLKSSLITPTVAAFPLES----ADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNH 688
Query: 606 PVDPGLVD---LASTSSELVEPLPAEPVLINPVLADSAAVD-PAVVPISDNLPPVDAVPS 661
PV G + L T+SE P+ P+ A + P VP S +LPP P
Sbjct: 689 PVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVP-SPSLPPA-GTPP 746
Query: 662 GPAPVDLALVDPVPNDLTPVDPVLVKSRPTD-PRRGAVSSALGGSAPQLLVESESLDP-- 718
G VD + + + PV S P + P + +SA S L ++S P
Sbjct: 747 GTKKVDGI------SHTSALAPVA--SSPKECPTEDSGASATASSKGTLTYLADSPSPLG 798
Query: 719 ----PKTIIPEVKEVVDSLKIESG---TSATTHEARPRPLSLSEYRRRRQQRQAETEERS 771
P+T P K+ G + + EA P + ++ + A T +
Sbjct: 799 VSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDS-PATTHSPT 857
Query: 772 PQPPTG------------KWPSLPETPTGLADIPCLVIP------PAPAKKTALQRSPET 813
P P G K +LP T + L P PAP + AL + +
Sbjct: 858 PPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSS 917
Query: 814 PLEICLVPVGPS-PASPSPEPPVSKPVASSPTEQ----VPSQEM----PLLARPSPPVQS 864
P + P PASPSP+ + P A+ P+ + PS + P PSP
Sbjct: 918 PKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGP 977
Query: 865 VSPA---VPTPPSMSAALPFPAGGLGMPPSLPPPPLQPPSLPLSMGPVLPDPFTHYAPLP 921
+P+ PTPP+ + P P P PP P P P P P
Sbjct: 978 ATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPA 1037
Query: 922 SWPCYPHVSPSGYPCLPPPPTVPLVS--GTPGAYAVPPTCSVPWAPPPAPVSPYSSTCTY 979
+ P P SP+ P PT P + G A P P P P SP T
Sbjct: 1038 ATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPAT- 1096
Query: 980 GPLGWGPGPQHAPFWSTVPPPPLPPASIGRAVPQPKMESRGTPAG-PPENVLPLSMAPPL 1038
P P+ AP +PP PP+ G P + TPA PP L+ PP
Sbjct: 1097 ------PSPKGAP----MPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPP- 1145
Query: 1039 SLGLPGHGAPQT-EPTKVEVKPVPASPHPKHKVSALVQSPQMK--ALACVSAEGVTVEEP 1095
GAP T T K A+P PK + +P LA S +G
Sbjct: 1146 ------KGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPA 1199
Query: 1096 AS--------ERLKPETQETRPREKPPLPATKAVPTPRQSTVPKLPAVHPARLRKLSFLP 1147
A+ P+ T P PP P + TP P PA P + P
Sbjct: 1200 ATPPSPKGGLATPSPKGAPTTPAATPPSP-KGGLATPSPKGAPTTPAATPPSPKGGPATP 1258
Query: 1148 TPRTQGSEDVVQAFISEIGIEASDLSSLLEQFEKSEAKKECPPPAPADSLAVGNSGGVDI 1207
P+ + + G+ + + PP+P A G
Sbjct: 1259 PPKGAPTPPAATPPSLKGGLAT-------PPHKGAPNPAVVTPPSPKGGPATSPPKGAPT 1311
Query: 1208 PQEKRPLDRLQAPELANVAGL-TPPA-TPPHQLWKP-LAAVSLLAKAKSPKSTAQEGTLK 1264
P P +P G TPPA TPP P L A + +K +++EG
Sbjct: 1312 PPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTP 1371
Query: 1265 PEGVTEAKHPAAVRLQEGVHGPSRVHVGSGDHDYCVRSRTPPKKMPALVIPEVGSRWNVK 1324
P K A+ GP+ + GD PKK PA + G+ K
Sbjct: 1372 PAATPSHKGGPAMTPPSPKRGPA-IPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSK 1430
Query: 1325 RHQDITIKPVLSLGPAAPPPPCIAASREPLDHRTSSEQADPSAPCLAPSSLLSPEASPCR 1384
D+T V + P A S T S + DP+ P + P SP+ P
Sbjct: 1431 --GDLTPPAVTPVSLKKAP----ATSAPKGGPATPSSKGDPTLPAVTPP---SPKEPPAP 1481
Query: 1385 NDMNTRTPPE 1394
+ T + P+
Sbjct: 1482 KQVATSSSPK 1491
Score = 115 bits (289), Expect = 3e-25
Identities = 239/971 (24%), Positives = 316/971 (32%), Gaps = 168/971 (17%)
Query: 536 SPKNLERSAGQSSPA-KEGPLDLYPKLADT--IQTNPIPTHLSLVDSAQASPMPVDSVEA 592
SPK + P+ K GP PK A T T P P S + +P P +
Sbjct: 935 SPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPP 994
Query: 593 DPTAVGPVLAGP--VPVDPGLVDLASTSSELVEPLPAEPVLINPVLADSAAVDPAVVPIS 650
P GP P P P + + S P P A+ PA P S
Sbjct: 995 SPKG-GPATPSPKGAPTPPAVTPPSPKGSPAATPFPK-----------GASTPPAATPPS 1042
Query: 651 DN-LPPVDAVPSGPAPVDLALVDPVPNDLTPVDPVLVKSRPTDPRRGAVSSALGGSAPQL 709
P +P G AP A P P P P L K PT P S G + P
Sbjct: 1043 PKGSPAATPLPKG-APTTPAATLPSPKG-GPATPSL-KGAPTPPAATPPSPKGGPATPS- 1098
Query: 710 LVESESLDPPKTIIPEVKEVVDSLKIESGTSATTHEARPRPLSLSEYRRRRQQRQAETEE 769
+ PP P K L A T A P + T
Sbjct: 1099 --PKGAPMPPAATPPSPK---GGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPA 1153
Query: 770 RSPQPPTGKWPSLPETPTGLADIPCLVIPPAPAKKTALQRSPETPLEICLVPVGPSP--A 827
+P P G + P P G P PP+P A P P P A
Sbjct: 1154 ATPPSPKGGLATPP--PKGAPTTPAAT-PPSPKGGLATPSPKGAPTTPAATPPSPKGGLA 1210
Query: 828 SPSPEPPVSKPVASSPTEQ----VPSQE-MPLLARPSPPVQSVSPAVPTP---PSMSAAL 879
+PSP+ + P A+ P+ + PS + P +PP PA P P P+ AA
Sbjct: 1211 TPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAAT 1270
Query: 880 PFPA--GGLGMPP--SLPPPPLQPPSLPLSMGPVLPDPFTHYAPLPSWPCYPHVSPSGYP 935
P P+ GGL PP P P + P P GP P AP P P SP G P
Sbjct: 1271 P-PSLKGGLATPPHKGAPNPAVVTPPSPKG-GPATSPP--KGAPTP--PAATPPSPKGSP 1324
Query: 936 CLPPPPTVPLVSGTPGAYAVPPTCSVPWAPPPAPVS---PYSSTCTYGPLGWGPGPQHAP 992
PPP P TP A P P P P S P + + GP P H
Sbjct: 1325 GTPPPKGAP----TPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKG 1380
Query: 993 FWSTVPPPPLPPASIGRAVPQPKMESRGTPAGPPENVLPLS--MAPPLSLGLPGHGAPQ- 1049
+ PP P G A+P PK G P P V+PLS AP + G P
Sbjct: 1381 GPAMTPPSP----KRGPAIPSPK----GDPTSPA--VIPLSPKKAPATPVTREGAATPSK 1430
Query: 1050 ---TEP--TKVEVKPVPASPHPKHKVSALVQSPQMKALACVSAEGVTVEEPASERLKPET 1104
T P T V +K PA+ PK + +P K + A VT P S + P
Sbjct: 1431 GDLTPPAVTPVSLKKAPATSAPKGGPA----TPSSKGDPTLPA--VT---PPSPKEPPAP 1481
Query: 1105 QETRPREKPPLPATKAVPTPRQSTVPKLPAVHPARLRKLSFLPTPRTQGSEDVVQAFISE 1164
++ P KA TP P LPAV P+ +++ P+ R +
Sbjct: 1482 KQVATSSSPK----KAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKK 1537
Query: 1165 IGIEASDLSSLLEQFEKSEAKKECPP-PAPADSLAVGNSGGVDIPQEKRPLDRLQAPELA 1223
+ +L+ + K+ P P P ++ A +S P P AP
Sbjct: 1538 TPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPK 1597
Query: 1224 NVA------------GLTPPATPPHQLWK--------------PLAAVSLLAKAKSPKS- 1256
+ TPPA P K P+ SL SP S
Sbjct: 1598 ELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASV 1657
Query: 1257 TAQEGTLKPE---GVTEAKHPAAVRLQEGVHGPSRVHV-----GSGDHDYCVRSRTPP-- 1306
T + G P+ G+ K P A++ P + G + +PP
Sbjct: 1658 TCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPIC 1717
Query: 1307 --------------KKMPALVIPEVGSRWNVKRHQDITIKPVLSLGP------------- 1339
PA ++P + +D + P L P
Sbjct: 1718 PDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAA 1777
Query: 1340 --------------AAPPPPC-IAASREPLDHRTSSEQADPSAPCLAPSSLLSPEASPCR 1384
AAP PP + + P+ +Q PS+P L S P A
Sbjct: 1778 FEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADE 1837
Query: 1385 NDMNTRTPPEP 1395
+++ PPEP
Sbjct: 1838 DELLPLIPPEP 1848
Score = 86.7 bits (213), Expect = 2e-16
Identities = 171/751 (22%), Positives = 242/751 (32%), Gaps = 112/751 (14%)
Query: 521 PRAWARAWAAALENSSPKNLERSAGQSSPAKEGPLDL-YPKLADTIQ--TNPIPTHLSLV 577
P A + L SPK + + P+ +G L PK A T T P P
Sbjct: 1198 PAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPAT 1257
Query: 578 DSAQASPMPVDSVEADPTAVGPVLAGPVPVDPGLVDLASTSSELVEPLPAEPVLINPVLA 637
+ +P P P A P L G + P A + + P P +P
Sbjct: 1258 PPPKGAPTP-------PAATPPSLKGGLATPPHKG--APNPAVVTPPSPKGGPATSP--P 1306
Query: 638 DSAAVDPAVVPISDNLPPVDAVPSGPAPVDLALVDPVPNDLTPVDPVLVKSRPTDPRRGA 697
A PA P S P P G AP A+ P P P L + P+
Sbjct: 1307 KGAPTPPAATPPSPKGSPGTPPPKG-APTPPAVTPPSPKGT----PTLPATTPSSKGGPT 1361
Query: 698 VSSALGGSAPQLLVESESLDPPKTI-IPEVKEVVDSLKIESGTSATTHEARPRPLSLSEY 756
S+ G P S P T P+ + S K + + A PLS
Sbjct: 1362 TPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVI------PLSPK-- 1413
Query: 757 RRRRQQRQAETEERSPQPPTGKWPSLPETPTGLADIPCLVIPPAPAKKTALQRSPETPLE 816
K P+ P T G A + P +L+++P T
Sbjct: 1414 ---------------------KAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATS-- 1450
Query: 817 ICLVPVGPSPASPSPEPPVSKPVASSPTEQVPSQEMPLLARPSPPVQSVSPAVPTPPSMS 876
P G PA+PS + + P + P+ + P + SP +PA P++
Sbjct: 1451 ---APKG-GPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLP 1506
Query: 877 AALPFPAGGLGMPPSLPPPPLQPPSLPLS-MGPVLPDPFTHYAPLPSWPCYPHVSPSGYP 935
A +P + PS P+ P + LS P P P P SP P
Sbjct: 1507 AVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIP----PAMTVPSPKKTP 1562
Query: 936 CLPPPPTVPLVSGTPGAYAVPPTCSVPWAPPPAPVSPYSSTCTYGPLGWGPGPQHAPFWS 995
+P P P + A + P + P+P P P P+ AP
Sbjct: 1563 AIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSP-----KELLIPPAVTSPSPKEAP--- 1614
Query: 996 TVPPPPLPPA-SIGRAVPQPKMESRGTPAGPPENVLPLSMAPPLSLGLPGHGAPQTEPTK 1054
PP PP+ G A P PK GTP PP L +P T P
Sbjct: 1615 -TPPAVTPPSPEKGPATPAPK----GTPTSPPVTPSSLKDSP-------------TSPAS 1656
Query: 1055 VEVKPVPASPHPKHKVSALVQSPQMKALACVSAEGVTVEEPASERLKPETQETRPREKPP 1114
V K P + A +K + A T A R P+T+++ P
Sbjct: 1657 VTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPI 1716
Query: 1115 LPATKAVPTPRQSTVPKLPAVHPARLRKLSFLPTPRTQGSEDVVQAFISEIGIEASDLSS 1174
P P+ + + L V PA L + + +G + A S G A S
Sbjct: 1717 CPD----PSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKD----ASHSPKGPLAPPESK 1768
Query: 1175 LLEQFEKSEAKKECPPPAPADSLAVGNSGGVDIPQEKRPLDRLQAPELANVAGLTPPATP 1234
+ +K P P A S++ S V +P P+ P P
Sbjct: 1769 ASTPLTAAAFEKVLPKPESA-SVSAAPSPPVSLPLAPSPV----------------PTLP 1811
Query: 1235 PHQLWKPLAAVSLLAKAKSPKSTAQEGTLKP 1265
P Q + P + +L P + A E L P
Sbjct: 1812 PKQQFLPSSPGLVLESPSKPLAPADEDELLP 1842
Score = 64.3 bits (155), Expect = 9e-10
Identities = 135/570 (23%), Positives = 194/570 (34%), Gaps = 131/570 (22%)
Query: 392 PTLESETEAAVPKVTLCSEKEGLSLNSEEKLDSACLLKPR-EVVEP-VVPKEPQNPPANA 449
PT S E P S K G ++ + P+ + P V+P P+ PA
Sbjct: 1360 PTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATP 1419
Query: 450 AP--GSQRARKGRKKKSKEQPAACVEGYARRLRS------SSRGQSTVGTEVTSQVDNLQ 501
G+ KG P + + A SS+G T+ VT
Sbjct: 1420 VTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPA-VTPPSPKEP 1478
Query: 502 KQPQEELQKESGPLQGKGKPRAWARAWAAALENSSPKNLERS-AGQSSP--------AKE 552
P++ + S P + P A+ SSPK + + + + P +K+
Sbjct: 1479 PAPKQ-VATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKK 1537
Query: 553 GPLDLYPK--LADTIQTNPIPTHLSLVDSAQASPMPVDSVEADPTAVGPVLAGPVPVDPG 610
P L PK L T P P + + + +P S EA + P V P
Sbjct: 1538 TPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEA---------SSPPAVTPS 1588
Query: 611 LVDLASTSSELVEPLPAEPVLINPVLADSAAVDPAVVPISDNLPPVDAVPSGPAPVDLAL 670
A + EL+ P P + +P + A PAV P S P P G
Sbjct: 1589 TYKGAPSPKELLIP----PAVTSPSPKE-APTPPAVTPPSPEKGPATPAPKG-------- 1635
Query: 671 VDPVPNDLTPVDPVLVKSRPTDPRRGAVSSALGGSAPQLLVESESLDPPKTIIPEVKEVV 730
P PV P +K PT P +V+ +G + PQ S+ L P K +KEV+
Sbjct: 1636 ---TPTS-PPVTPSSLKDSPTSP--ASVTCKMGATVPQA---SKGL-PAKKGPTALKEVL 1685
Query: 731 DSLKIESGTSATTHEARPRPLSLSEYRRRRQQRQAETEERSPQPPTGKWPSLPETPTGLA 790
+ ES P+ + R+ Q +++ + PP PS G
Sbjct: 1686 VAPAPES-----------TPIITAPTRKGPQTKKSS----ATSPPICPDPSAKNGSKG-- 1728
Query: 791 DIPCLVIPPAP-----------AKKTALQRSPETPLE------------ICLVPVGPSPA 827
P + PAP AK SP+ PL V P P
Sbjct: 1729 --PLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPE 1786
Query: 828 SPS----PEPPVSKPVASSPTEQVPSQEMPLLARP-----SP------------------ 860
S S P PPVS P+A SP +P ++ L + P SP
Sbjct: 1787 SASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPP 1846
Query: 861 -------PVQSVSPAVPTPPSMSAALPFPA 883
P QSV +PTP S +P P+
Sbjct: 1847 EPISGGVPFQSVLVNMPTPKSAGIPVPTPS 1876
Score = 56.2 bits (134), Expect = 3e-07
Identities = 212/1032 (20%), Positives = 332/1032 (32%), Gaps = 190/1032 (18%)
Query: 571 PTHLSLVDSAQASPMPVDSVEADPTAVGPV-LAGPVPVDPGLVDLASTSSELVEPL---- 625
PT + S Q + SV P G + L GPV P + L++ S +V
Sbjct: 235 PTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVS-PPAALSLSTQSLPVVTSSQKTA 293
Query: 626 -----PAEPVLINPVLAD-----------------SAAVDPAVVPISDNLPPVDAVPSGP 663
P P+ + LA SA DP V IS VD +G
Sbjct: 294 GPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTIS-----VDHSSTGA 348
Query: 664 A-PVDLALVDPVP--NDLTPVD----PVLVKSRPTDPRRGAVSSALGGSAPQLLVESESL 716
+ P +++ P+P N++ P PV+ S P +SS + L V +
Sbjct: 349 SYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGP--STISSITCSPSGSLNVATSFS 406
Query: 717 DPPKTIIPEVKEVVDSLKIESGTSATTHEARPRPLSLSEYRRRRQQRQAETEERSPQPPT 776
P T SL ++S +AT H + +S T P T
Sbjct: 407 LSPTT----------SLILKSSPNATYHYPLVAQMPVSSV--------GTTPLVVTNPCT 448
Query: 777 GKWPSLPETPTGLADIPCLVIPPAPAKKTALQRSPETPLEICLVPVGPSPAS-------- 828
+ PT ++ V PP + + P +P + + PV P S
Sbjct: 449 -----IAAAPTTTFEVATCVSPPMSSGPIS-NIEPTSPAALVMAPVAPKEPSTQVATTLR 502
Query: 829 -----PSPEPPVSKPVASSPTEQVPSQE------MPLLARPSPPVQS--VSPAVPTPPSM 875
P P+P K + SS + P+Q+ L P P Q+ + PT +
Sbjct: 503 IPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPL 562
Query: 876 SAALPFPAGGLGMPPSLPPPPLQPPS--LPLSMGPVLP---DPFTHYAPLPSWPCYPHVS 930
A P + S P PL P + S+G LP + +PL +
Sbjct: 563 VQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIK 622
Query: 931 PSGY-------PCLPPPPTVPLVSGTPGAYAVPPTCSVPWAPPPAPVSPYSSTCTYGPLG 983
Y P L P V+ P A P + A + + +S G +
Sbjct: 623 TDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVS 682
Query: 984 WGPGPQHAPFWSTVPPPPLPPASIGRAVPQPKMESRGTPAGPPENVLPLSMAPPLSLGLP 1043
P H T+ PL P + P ++ P + L +AP + +P
Sbjct: 683 LAP-KNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAP------LATLVLAPEIPKSVP 735
Query: 1044 GHGAPQTEPTKVEVKPVPASPHPKHKVSALVQSPQMKALACVSAEGVTVEEPASERLKPE 1103
P P P K KV + + + +A E T + AS +
Sbjct: 736 SPSLP----------PAGTPPGTK-KVDGISHTSALAPVASSPKECPTEDSGASATASSK 784
Query: 1104 TQETRPREKP-PL-----PATKAVPTPRQSTVPKLPAVH---PARLRKLSFLPTPRTQGS 1154
T + P PL P TK PT + S P P + P + SFLP
Sbjct: 785 GTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPE------ 838
Query: 1155 EDVVQAFISEIGIEASDLSSLLEQFEKSEAKKECPPPAPADSLAVGNSGGVDIPQEKRPL 1214
+ + + S S + K P P+ L + GV +P ++ P
Sbjct: 839 --------NSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPL---SPKGVTLPPKETP- 886
Query: 1215 DRLQAPELANVA-GLTPPATPPHQLWKPLAAVSLLAKAKSPKSTAQEGTLKPEGVTEAKH 1273
P + N+ PATP P A +L + SPK T P+G+ +
Sbjct: 887 ----TPSVVNLPFPKEGPATP-----APKQAPALSMTSSSPKKA--RATPAPKGIPASPS 935
Query: 1274 PAAVRLQEGVHGPSRVHVGSGDHDYCVRSRTPPKKMPALVIPEVGSRWNVKRHQDITIKP 1333
P PS PK PA P+ P
Sbjct: 936 PKGAPTPPAATPPS------------------PKGGPATPSPKWAPTPPAATPPSPKGGP 977
Query: 1334 VLSLGPAAPPPPCIAASREPLDHRTSSEQADPSAPCLAPSSLL-SPEASPCRNDMNT--- 1389
AP PP T S + P+ P + P S SP A+P +T
Sbjct: 978 ATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPA 1037
Query: 1390 RTPPEPSAKQRSMRCYRKACRS------------ASPSSQGWQGRRGRNSRSVSSGSNRT 1437
TPP P + + A + A+PS +G S G
Sbjct: 1038 ATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATP 1097
Query: 1438 SEASSSSSSSSSSSRSRSRSLSPPHKRWRRSSCSSSGRSRRCSSSSSSSSSSSSSSSSSS 1497
S + +++ + +PPHK + ++ + ++ + ++ +++
Sbjct: 1098 SPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPP 1157
Query: 1498 SSRSRSRSPSPR 1509
S + +P P+
Sbjct: 1158 SPKGGLATPPPK 1169
Score = 43.9 bits (102), Expect = 0.001
Identities = 80/335 (23%), Positives = 126/335 (37%), Gaps = 47/335 (14%)
Query: 824 PSPASPSPEPPVSKPVASSPTEQVPSQEMPLLARPSPPVQSVSPAVPTPPSMSAALPFPA 883
P P + + P+S ++ + P +P P+P +S A + A PFP+
Sbjct: 17 PQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAA-------NQASPFPS 69
Query: 884 GGLGMPPSLPPPPLQPPSLPLSMGPVLPDPFTHYAP--LPSWPCYPHVSPSGYPCLPPPP 941
P ++ PL+ P S G LP AP LP+ P +SP+ L P
Sbjct: 70 -----PSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNL-IGPPISPAAL-ALASPM 122
Query: 942 TVPLVSGTPGAYAVPPTCSVPWAPPPA-PVSPYSSTCTYGPLGWGPGPQHAPFWSTVPPP 1000
P + GTP + A P V AP S + P + + P
Sbjct: 123 IAPTLKGTPSSSA--PLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIA 180
Query: 1001 PLPPASIGRAVPQPKMES-RGTPAGP-PENVLPLSMAPPLSLGLPGHGA-PQTEPTKVEV 1057
P P + VP + + +GTP+ P + +P P++ G + PQT PT
Sbjct: 181 PSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPT---- 236
Query: 1058 KPVPASPHPKHKVSALVQSPQMKALACVSAEGVTVEEPASERLK----PETQETRPREKP 1113
+ + SPQ+K +S+ ++ + P S LK P + +
Sbjct: 237 ------------TTLAIASPQVKD-TTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSL 283
Query: 1114 PLPATKAVPTPRQSTVPKLP---AVHPARLRKLSF 1145
P+ T + T +T P P H A L + SF
Sbjct: 284 PV-VTSSQKTAGPNTPPDFPISLGSHLAPLHQSSF 317
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 114 bits (286), Expect = 6e-25
Identities = 173/742 (23%), Positives = 245/742 (33%), Gaps = 90/742 (12%)
Query: 437 VVPKEPQNPPANAAPGSQRARKGRKKKSKEQPAACVEGYARRLRSSSRGQSTVGTEVTSQ 496
+ +P NP + P S +++ +KE E ++S+ G+ T +
Sbjct: 118 ITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEK--TTSAKE 175
Query: 497 VDNLQKQPQEELQKESGPLQGKGKPRAWARAWAAALENSSPKNLERSAGQSSPAKEGPLD 556
+++K ++L S L K P+A AL +S + P
Sbjct: 176 TQSIEKTSAKDLAPTSKVL-AKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTP 234
Query: 557 LYPKLADTIQTNPIPTHLSLVDSAQASPMPVDSVEADPTAVGPVLAGPVPVDPGLVDLAS 616
K A T P PT + P P + E PT P + A
Sbjct: 235 TTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT------TPKEPAPTTTKEPAP 288
Query: 617 TSSELVEPLPAEPVLINPVL-ADSAAVDPAVVPISDNLPPVDAVPSGPAPVDLALVDPVP 675
T+++ P EP P A + +PA + P P PAP P
Sbjct: 289 TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE---PTPTTPKEPAPTTKEPAPTTP 345
Query: 676 NDLTPVDPVLVKSRPTDPRRGAVSSALGGSAPQLLVESESLDPPKTIIPEVKEVVDSLKI 735
+ P P K PT P+ A ++ AP E P + K + K
Sbjct: 346 KEPAPTAP--KKPAPTTPKEPAPTTP-KEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKE 402
Query: 736 ESGT---SATTHEARPRPLSLSEYRRRRQQRQAETEERSPQPPTGKWPSLPETPTGLADI 792
+ T SA T P P + E + A T + P P T K P+ P TP A
Sbjct: 403 PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA-PTTPKEPAPT 461
Query: 793 ----PCLVIPPAPAKKTALQRSPETPLEICLVPVGPSPASP-SPEPPVSKPVASSPTEQV 847
P P PA T + +P TP + L P P +P +PE KP ++P E
Sbjct: 462 TTKKPAPTTPKEPAPTTPKETAPTTPKK--LTPTTPEKLAPTTPE----KPAPTTPEELA 515
Query: 848 PSQEMPLLARPSPPVQSVSPAVPTPPSMSAALP-FPAGGLGMPPSLPPP--PLQP-PSLP 903
P+ P+P +P P P + AA P P P P P P +P P+ P
Sbjct: 516 PTTP----EEPTP----TTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP 567
Query: 904 LSMGPVLPD---PFTHYAPLPSWPCYP---------HVSPSGYPCLPPPPTVPLVSGTPG 951
P P P T P P+ P P P+ C P PT P GT
Sbjct: 568 KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP--KGTAP 625
Query: 952 AYAVPPTCSVPWAPPPAPVSPYSSTCTYGPLGWGPGPQHAPFWSTVPPPPLPPASIGRAV 1011
P + P P P P G P P T P P P
Sbjct: 626 TTPKEPAPTTPKEPAPTT-----------PKGTAPTTLKEPA-PTTPKKPAPK----ELA 669
Query: 1012 PQPKMESRGTPAGPPENVLPLSMAPPLSLGLPGHGAPQTEPTKVEVKPVPASPHPKHKVS 1071
P T + P P AP P AP T KP P +P +
Sbjct: 670 PTTTKGPTSTTSDKPAPTTPKETAPT----TPKEPAPTTPK-----KPAPTTPETPPPTT 720
Query: 1072 ALVQSPQMKALACVSAEGVTVEEPASERLKPETQETRPREKPPLPATKAVPTPR--QSTV 1129
+ V +P + E T+ + E + E P+ P VPT + +T
Sbjct: 721 SEVSTP------TTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATK 774
Query: 1130 PKLPAVHPARLRKLSFLPTPRT 1151
P++ + + TP T
Sbjct: 775 PEMTTTAKDKTTERDLRTTPET 796
Score = 85.9 bits (211), Expect = 3e-16
Identities = 185/795 (23%), Positives = 246/795 (30%), Gaps = 120/795 (15%)
Query: 654 PPVDAVPSGPAPVDLALVDP----VPNDLTPVDPVLVKSRPTDPRRGAVSSALGGSAPQL 709
P VD SG D + P ++ P + ++P +PR ++ L
Sbjct: 83 PVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSL 142
Query: 710 LVESESLDPPKTIIPEVKEVVDSLKIESGTSATTHEARPRPLSLSEYRRRRQQRQAETEE 769
V E+ E KE + K T+ + + + S E + E
Sbjct: 143 TVNKETT-------VETKETTTTNK------QTSTDGKEKTTSAKE------TQSIEKTS 183
Query: 770 RSPQPPTGKWPSLPETPTGLADIPCLVIPPAPAKKTALQRSPETPLEICLVPVGPSPASP 829
PT K + PT A+ PA T + +P TP E PAS
Sbjct: 184 AKDLAPTSK---VLAKPTPKAE----TTTKGPALTTPKEPTPTTPKE---------PAST 227
Query: 830 SPEPPVSKPVASSPTEQVPSQEMPLLARPSP-------PVQSVSPAVPTPPSMSAAL--- 879
+P+ P + S+PT P + P + +P P + PA TP +
Sbjct: 228 TPKEPTPTTIKSAPT--TPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKE 285
Query: 880 PFPAGGLGMPPSLPPPPLQPPSLPLSMGPVLPDPFTHYAPLPSWPCYP-HVSPSGYPCLP 938
P P P + P P P P P P T P P+ P P + P P
Sbjct: 286 PAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP 345
Query: 939 --PPPTVPLVSGTPGAYAVPPTCSVPWAP-------PPAPVSPYSSTCTYGPLGW-GPGP 988
P PT P PT AP P P P +T P P P
Sbjct: 346 KEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAP 405
Query: 989 QHAPFWSTVPPPPLPPASIGRAVPQPKMESRGTPAGPPENVLPLSMAPPLSLGLPGHGAP 1048
T P P P + A PK + TP P P AP P AP
Sbjct: 406 TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTT-PKEPAPT----TPKEPAP 460
Query: 1049 QTEPTKVEVKPVPASPHPKHKVSALVQSPQMKALACVSAEGV---TVEEPA---SERLKP 1102
T TK P P P +P K L + E + T E+PA E L P
Sbjct: 461 TT--TKKPAPTTPKEPAPTTPKETAPTTP--KKLTPTTPEKLAPTTPEKPAPTTPEELAP 516
Query: 1103 ETQE----TRPREKPPLPATKAVP-TPRQ--STVPKLPA----VHPARLRKLSFLPTPRT 1151
T E T P E P A P TP++ T PK PA PA PT
Sbjct: 517 TTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPT-TP 575
Query: 1152 QGSEDVVQAFISEIGIEASDLSSLLEQFEKSEAKKECPPPAPADSLAVGNSGGVDIPQEK 1211
+G+ + + L K C PAP + P+E
Sbjct: 576 KGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPT----TPKEP 631
Query: 1212 RPLDRLQAPELANVAGLTPPATPPHQLWKPLAAVSLLAKAKSPKSTAQEGTLKPEGVTEA 1271
P + A TP T P L +P K +PK A T P T
Sbjct: 632 APTTPKEP------APTTPKGTAPTTLKEPAPTT---PKKPAPKELAPTTTKGPTSTTSD 682
Query: 1272 KHPAAVRLQEGVHGPSRVHVGSGDHDYCVRSRTPPKKMPALVIPEVGSRWNVKRHQDITI 1331
K + P + T PKK PA PE + T
Sbjct: 683 KPAPTTPKETAPTTPKE------------PAPTTPKK-PAPTTPETPPPTTSEVSTPTTT 729
Query: 1332 KPVLSLGPAAPPPPCIAASREPLDHRTSSEQADPSAPCLAPSSLLSPEASPCRNDMNT-- 1389
K ++ +P S EP + +P P + PE + D T
Sbjct: 730 KEPTTI-HKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTER 788
Query: 1390 --RTPPEPSAKQRSM 1402
RT PE + M
Sbjct: 789 DLRTTPETTTAAPKM 803
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 114 bits (286), Expect = 6e-25
Identities = 173/742 (23%), Positives = 245/742 (33%), Gaps = 90/742 (12%)
Query: 437 VVPKEPQNPPANAAPGSQRARKGRKKKSKEQPAACVEGYARRLRSSSRGQSTVGTEVTSQ 496
+ +P NP + P S +++ +KE E ++S+ G+ T +
Sbjct: 159 ITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEK--TTSAKE 216
Query: 497 VDNLQKQPQEELQKESGPLQGKGKPRAWARAWAAALENSSPKNLERSAGQSSPAKEGPLD 556
+++K ++L S L K P+A AL +S + P
Sbjct: 217 TQSIEKTSAKDLAPTSKVL-AKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTP 275
Query: 557 LYPKLADTIQTNPIPTHLSLVDSAQASPMPVDSVEADPTAVGPVLAGPVPVDPGLVDLAS 616
K A T P PT + P P + E PT P + A
Sbjct: 276 TTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT------TPKEPAPTTTKEPAP 329
Query: 617 TSSELVEPLPAEPVLINPVL-ADSAAVDPAVVPISDNLPPVDAVPSGPAPVDLALVDPVP 675
T+++ P EP P A + +PA + P P PAP P
Sbjct: 330 TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE---PTPTTPKEPAPTTKEPAPTTP 386
Query: 676 NDLTPVDPVLVKSRPTDPRRGAVSSALGGSAPQLLVESESLDPPKTIIPEVKEVVDSLKI 735
+ P P K PT P+ A ++ AP E P + K + K
Sbjct: 387 KEPAPTAP--KKPAPTTPKEPAPTTP-KEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKE 443
Query: 736 ESGT---SATTHEARPRPLSLSEYRRRRQQRQAETEERSPQPPTGKWPSLPETPTGLADI 792
+ T SA T P P + E + A T + P P T K P+ P TP A
Sbjct: 444 PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA-PTTPKEPAPT 502
Query: 793 ----PCLVIPPAPAKKTALQRSPETPLEICLVPVGPSPASP-SPEPPVSKPVASSPTEQV 847
P P PA T + +P TP + L P P +P +PE KP ++P E
Sbjct: 503 TTKKPAPTTPKEPAPTTPKETAPTTPKK--LTPTTPEKLAPTTPE----KPAPTTPEELA 556
Query: 848 PSQEMPLLARPSPPVQSVSPAVPTPPSMSAALP-FPAGGLGMPPSLPPP--PLQP-PSLP 903
P+ P+P +P P P + AA P P P P P P +P P+ P
Sbjct: 557 PTTP----EEPTP----TTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP 608
Query: 904 LSMGPVLPD---PFTHYAPLPSWPCYP---------HVSPSGYPCLPPPPTVPLVSGTPG 951
P P P T P P+ P P P+ C P PT P GT
Sbjct: 609 KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP--KGTAP 666
Query: 952 AYAVPPTCSVPWAPPPAPVSPYSSTCTYGPLGWGPGPQHAPFWSTVPPPPLPPASIGRAV 1011
P + P P P P G P P T P P P
Sbjct: 667 TTPKEPAPTTPKEPAPTT-----------PKGTAPTTLKEPA-PTTPKKPAPK----ELA 710
Query: 1012 PQPKMESRGTPAGPPENVLPLSMAPPLSLGLPGHGAPQTEPTKVEVKPVPASPHPKHKVS 1071
P T + P P AP P AP T KP P +P +
Sbjct: 711 PTTTKGPTSTTSDKPAPTTPKETAPT----TPKEPAPTTPK-----KPAPTTPETPPPTT 761
Query: 1072 ALVQSPQMKALACVSAEGVTVEEPASERLKPETQETRPREKPPLPATKAVPTPR--QSTV 1129
+ V +P + E T+ + E + E P+ P VPT + +T
Sbjct: 762 SEVSTP------TTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATK 815
Query: 1130 PKLPAVHPARLRKLSFLPTPRT 1151
P++ + + TP T
Sbjct: 816 PEMTTTAKDKTTERDLRTTPET 837
Score = 85.9 bits (211), Expect = 3e-16
Identities = 185/795 (23%), Positives = 246/795 (30%), Gaps = 120/795 (15%)
Query: 654 PPVDAVPSGPAPVDLALVDP----VPNDLTPVDPVLVKSRPTDPRRGAVSSALGGSAPQL 709
P VD SG D + P ++ P + ++P +PR ++ L
Sbjct: 124 PVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSL 183
Query: 710 LVESESLDPPKTIIPEVKEVVDSLKIESGTSATTHEARPRPLSLSEYRRRRQQRQAETEE 769
V E+ E KE + K T+ + + + S E + E
Sbjct: 184 TVNKETT-------VETKETTTTNK------QTSTDGKEKTTSAKE------TQSIEKTS 224
Query: 770 RSPQPPTGKWPSLPETPTGLADIPCLVIPPAPAKKTALQRSPETPLEICLVPVGPSPASP 829
PT K + PT A+ PA T + +P TP E PAS
Sbjct: 225 AKDLAPTSK---VLAKPTPKAE----TTTKGPALTTPKEPTPTTPKE---------PAST 268
Query: 830 SPEPPVSKPVASSPTEQVPSQEMPLLARPSP-------PVQSVSPAVPTPPSMSAAL--- 879
+P+ P + S+PT P + P + +P P + PA TP +
Sbjct: 269 TPKEPTPTTIKSAPT--TPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKE 326
Query: 880 PFPAGGLGMPPSLPPPPLQPPSLPLSMGPVLPDPFTHYAPLPSWPCYP-HVSPSGYPCLP 938
P P P + P P P P P P T P P+ P P + P P
Sbjct: 327 PAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP 386
Query: 939 --PPPTVPLVSGTPGAYAVPPTCSVPWAP-------PPAPVSPYSSTCTYGPLGW-GPGP 988
P PT P PT AP P P P +T P P P
Sbjct: 387 KEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAP 446
Query: 989 QHAPFWSTVPPPPLPPASIGRAVPQPKMESRGTPAGPPENVLPLSMAPPLSLGLPGHGAP 1048
T P P P + A PK + TP P P AP P AP
Sbjct: 447 TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTT-PKEPAPT----TPKEPAP 501
Query: 1049 QTEPTKVEVKPVPASPHPKHKVSALVQSPQMKALACVSAEGV---TVEEPA---SERLKP 1102
T TK P P P +P K L + E + T E+PA E L P
Sbjct: 502 TT--TKKPAPTTPKEPAPTTPKETAPTTP--KKLTPTTPEKLAPTTPEKPAPTTPEELAP 557
Query: 1103 ETQE----TRPREKPPLPATKAVP-TPRQ--STVPKLPA----VHPARLRKLSFLPTPRT 1151
T E T P E P A P TP++ T PK PA PA PT
Sbjct: 558 TTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPT-TP 616
Query: 1152 QGSEDVVQAFISEIGIEASDLSSLLEQFEKSEAKKECPPPAPADSLAVGNSGGVDIPQEK 1211
+G+ + + L K C PAP + P+E
Sbjct: 617 KGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPT----TPKEP 672
Query: 1212 RPLDRLQAPELANVAGLTPPATPPHQLWKPLAAVSLLAKAKSPKSTAQEGTLKPEGVTEA 1271
P + A TP T P L +P K +PK A T P T
Sbjct: 673 APTTPKEP------APTTPKGTAPTTLKEPAPTT---PKKPAPKELAPTTTKGPTSTTSD 723
Query: 1272 KHPAAVRLQEGVHGPSRVHVGSGDHDYCVRSRTPPKKMPALVIPEVGSRWNVKRHQDITI 1331
K + P + T PKK PA PE + T
Sbjct: 724 KPAPTTPKETAPTTPKE------------PAPTTPKK-PAPTTPETPPPTTSEVSTPTTT 770
Query: 1332 KPVLSLGPAAPPPPCIAASREPLDHRTSSEQADPSAPCLAPSSLLSPEASPCRNDMNT-- 1389
K ++ +P S EP + +P P + PE + D T
Sbjct: 771 KEPTTI-HKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTER 829
Query: 1390 --RTPPEPSAKQRSM 1402
RT PE + M
Sbjct: 830 DLRTTPETTTAAPKM 844
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 114 bits (286), Expect = 6e-25
Identities = 173/742 (23%), Positives = 245/742 (33%), Gaps = 90/742 (12%)
Query: 437 VVPKEPQNPPANAAPGSQRARKGRKKKSKEQPAACVEGYARRLRSSSRGQSTVGTEVTSQ 496
+ +P NP + P S +++ +KE E ++S+ G+ T +
Sbjct: 211 ITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEK--TTSAKE 268
Query: 497 VDNLQKQPQEELQKESGPLQGKGKPRAWARAWAAALENSSPKNLERSAGQSSPAKEGPLD 556
+++K ++L S L K P+A AL +S + P
Sbjct: 269 TQSIEKTSAKDLAPTSKVL-AKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTP 327
Query: 557 LYPKLADTIQTNPIPTHLSLVDSAQASPMPVDSVEADPTAVGPVLAGPVPVDPGLVDLAS 616
K A T P PT + P P + E PT P + A
Sbjct: 328 TTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT------TPKEPAPTTTKEPAP 381
Query: 617 TSSELVEPLPAEPVLINPVL-ADSAAVDPAVVPISDNLPPVDAVPSGPAPVDLALVDPVP 675
T+++ P EP P A + +PA + P P PAP P
Sbjct: 382 TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE---PTPTTPKEPAPTTKEPAPTTP 438
Query: 676 NDLTPVDPVLVKSRPTDPRRGAVSSALGGSAPQLLVESESLDPPKTIIPEVKEVVDSLKI 735
+ P P K PT P+ A ++ AP E P + K + K
Sbjct: 439 KEPAPTAP--KKPAPTTPKEPAPTTP-KEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKE 495
Query: 736 ESGT---SATTHEARPRPLSLSEYRRRRQQRQAETEERSPQPPTGKWPSLPETPTGLADI 792
+ T SA T P P + E + A T + P P T K P+ P TP A
Sbjct: 496 PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA-PTTPKEPAPT 554
Query: 793 ----PCLVIPPAPAKKTALQRSPETPLEICLVPVGPSPASP-SPEPPVSKPVASSPTEQV 847
P P PA T + +P TP + L P P +P +PE KP ++P E
Sbjct: 555 TTKKPAPTTPKEPAPTTPKETAPTTPKK--LTPTTPEKLAPTTPE----KPAPTTPEELA 608
Query: 848 PSQEMPLLARPSPPVQSVSPAVPTPPSMSAALP-FPAGGLGMPPSLPPP--PLQP-PSLP 903
P+ P+P +P P P + AA P P P P P P +P P+ P
Sbjct: 609 PTTP----EEPTP----TTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP 660
Query: 904 LSMGPVLPD---PFTHYAPLPSWPCYP---------HVSPSGYPCLPPPPTVPLVSGTPG 951
P P P T P P+ P P P+ C P PT P GT
Sbjct: 661 KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP--KGTAP 718
Query: 952 AYAVPPTCSVPWAPPPAPVSPYSSTCTYGPLGWGPGPQHAPFWSTVPPPPLPPASIGRAV 1011
P + P P P P G P P T P P P
Sbjct: 719 TTPKEPAPTTPKEPAPTT-----------PKGTAPTTLKEPA-PTTPKKPAPK----ELA 762
Query: 1012 PQPKMESRGTPAGPPENVLPLSMAPPLSLGLPGHGAPQTEPTKVEVKPVPASPHPKHKVS 1071
P T + P P AP P AP T KP P +P +
Sbjct: 763 PTTTKGPTSTTSDKPAPTTPKETAPT----TPKEPAPTTPK-----KPAPTTPETPPPTT 813
Query: 1072 ALVQSPQMKALACVSAEGVTVEEPASERLKPETQETRPREKPPLPATKAVPTPR--QSTV 1129
+ V +P + E T+ + E + E P+ P VPT + +T
Sbjct: 814 SEVSTP------TTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATK 867
Query: 1130 PKLPAVHPARLRKLSFLPTPRT 1151
P++ + + TP T
Sbjct: 868 PEMTTTAKDKTTERDLRTTPET 889
Score = 85.9 bits (211), Expect = 3e-16
Identities = 185/795 (23%), Positives = 246/795 (30%), Gaps = 120/795 (15%)
Query: 654 PPVDAVPSGPAPVDLALVDP----VPNDLTPVDPVLVKSRPTDPRRGAVSSALGGSAPQL 709
P VD SG D + P ++ P + ++P +PR ++ L
Sbjct: 176 PVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSL 235
Query: 710 LVESESLDPPKTIIPEVKEVVDSLKIESGTSATTHEARPRPLSLSEYRRRRQQRQAETEE 769
V E+ E KE + K T+ + + + S E + E
Sbjct: 236 TVNKETT-------VETKETTTTNK------QTSTDGKEKTTSAKE------TQSIEKTS 276
Query: 770 RSPQPPTGKWPSLPETPTGLADIPCLVIPPAPAKKTALQRSPETPLEICLVPVGPSPASP 829
PT K + PT A+ PA T + +P TP E PAS
Sbjct: 277 AKDLAPTSK---VLAKPTPKAE----TTTKGPALTTPKEPTPTTPKE---------PAST 320
Query: 830 SPEPPVSKPVASSPTEQVPSQEMPLLARPSP-------PVQSVSPAVPTPPSMSAAL--- 879
+P+ P + S+PT P + P + +P P + PA TP +
Sbjct: 321 TPKEPTPTTIKSAPT--TPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKE 378
Query: 880 PFPAGGLGMPPSLPPPPLQPPSLPLSMGPVLPDPFTHYAPLPSWPCYP-HVSPSGYPCLP 938
P P P + P P P P P P T P P+ P P + P P
Sbjct: 379 PAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP 438
Query: 939 --PPPTVPLVSGTPGAYAVPPTCSVPWAP-------PPAPVSPYSSTCTYGPLGW-GPGP 988
P PT P PT AP P P P +T P P P
Sbjct: 439 KEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAP 498
Query: 989 QHAPFWSTVPPPPLPPASIGRAVPQPKMESRGTPAGPPENVLPLSMAPPLSLGLPGHGAP 1048
T P P P + A PK + TP P P AP P AP
Sbjct: 499 TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTT-PKEPAPT----TPKEPAP 553
Query: 1049 QTEPTKVEVKPVPASPHPKHKVSALVQSPQMKALACVSAEGV---TVEEPA---SERLKP 1102
T TK P P P +P K L + E + T E+PA E L P
Sbjct: 554 TT--TKKPAPTTPKEPAPTTPKETAPTTP--KKLTPTTPEKLAPTTPEKPAPTTPEELAP 609
Query: 1103 ETQE----TRPREKPPLPATKAVP-TPRQ--STVPKLPA----VHPARLRKLSFLPTPRT 1151
T E T P E P A P TP++ T PK PA PA PT
Sbjct: 610 TTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPT-TP 668
Query: 1152 QGSEDVVQAFISEIGIEASDLSSLLEQFEKSEAKKECPPPAPADSLAVGNSGGVDIPQEK 1211
+G+ + + L K C PAP + P+E
Sbjct: 669 KGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPT----TPKEP 724
Query: 1212 RPLDRLQAPELANVAGLTPPATPPHQLWKPLAAVSLLAKAKSPKSTAQEGTLKPEGVTEA 1271
P + A TP T P L +P K +PK A T P T
Sbjct: 725 APTTPKEP------APTTPKGTAPTTLKEPAPTT---PKKPAPKELAPTTTKGPTSTTSD 775
Query: 1272 KHPAAVRLQEGVHGPSRVHVGSGDHDYCVRSRTPPKKMPALVIPEVGSRWNVKRHQDITI 1331
K + P + T PKK PA PE + T
Sbjct: 776 KPAPTTPKETAPTTPKE------------PAPTTPKK-PAPTTPETPPPTTSEVSTPTTT 822
Query: 1332 KPVLSLGPAAPPPPCIAASREPLDHRTSSEQADPSAPCLAPSSLLSPEASPCRNDMNT-- 1389
K ++ +P S EP + +P P + PE + D T
Sbjct: 823 KEPTTI-HKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTER 881
Query: 1390 --RTPPEPSAKQRSM 1402
RT PE + M
Sbjct: 882 DLRTTPETTTAAPKM 896
Score = 38.5 bits (88), Expect = 0.055
Identities = 24/69 (34%), Positives = 37/69 (53%)
Query: 1437 TSEASSSSSSSSSSSRSRSRSLSPPHKRWRRSSCSSSGRSRRCSSSSSSSSSSSSSSSSS 1496
+ +A S +S + + RS PP+K+ + S + S S + SSSSSSSSSS
Sbjct: 75 SKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSSS 134
Query: 1497 SSSRSRSRS 1505
SS+ + +S
Sbjct: 135 SSTIRKIKS 143
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 114 bits (286), Expect = 6e-25
Identities = 173/742 (23%), Positives = 245/742 (33%), Gaps = 90/742 (12%)
Query: 437 VVPKEPQNPPANAAPGSQRARKGRKKKSKEQPAACVEGYARRLRSSSRGQSTVGTEVTSQ 496
+ +P NP + P S +++ +KE E ++S+ G+ T +
Sbjct: 252 ITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEK--TTSAKE 309
Query: 497 VDNLQKQPQEELQKESGPLQGKGKPRAWARAWAAALENSSPKNLERSAGQSSPAKEGPLD 556
+++K ++L S L K P+A AL +S + P
Sbjct: 310 TQSIEKTSAKDLAPTSKVL-AKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTP 368
Query: 557 LYPKLADTIQTNPIPTHLSLVDSAQASPMPVDSVEADPTAVGPVLAGPVPVDPGLVDLAS 616
K A T P PT + P P + E PT P + A
Sbjct: 369 TTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT------TPKEPAPTTTKEPAP 422
Query: 617 TSSELVEPLPAEPVLINPVL-ADSAAVDPAVVPISDNLPPVDAVPSGPAPVDLALVDPVP 675
T+++ P EP P A + +PA + P P PAP P
Sbjct: 423 TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE---PTPTTPKEPAPTTKEPAPTTP 479
Query: 676 NDLTPVDPVLVKSRPTDPRRGAVSSALGGSAPQLLVESESLDPPKTIIPEVKEVVDSLKI 735
+ P P K PT P+ A ++ AP E P + K + K
Sbjct: 480 KEPAPTAP--KKPAPTTPKEPAPTTP-KEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKE 536
Query: 736 ESGT---SATTHEARPRPLSLSEYRRRRQQRQAETEERSPQPPTGKWPSLPETPTGLADI 792
+ T SA T P P + E + A T + P P T K P+ P TP A
Sbjct: 537 PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA-PTTPKEPAPT 595
Query: 793 ----PCLVIPPAPAKKTALQRSPETPLEICLVPVGPSPASP-SPEPPVSKPVASSPTEQV 847
P P PA T + +P TP + L P P +P +PE KP ++P E
Sbjct: 596 TTKKPAPTTPKEPAPTTPKETAPTTPKK--LTPTTPEKLAPTTPE----KPAPTTPEELA 649
Query: 848 PSQEMPLLARPSPPVQSVSPAVPTPPSMSAALP-FPAGGLGMPPSLPPP--PLQP-PSLP 903
P+ P+P +P P P + AA P P P P P P +P P+ P
Sbjct: 650 PTTP----EEPTP----TTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP 701
Query: 904 LSMGPVLPD---PFTHYAPLPSWPCYP---------HVSPSGYPCLPPPPTVPLVSGTPG 951
P P P T P P+ P P P+ C P PT P GT
Sbjct: 702 KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP--KGTAP 759
Query: 952 AYAVPPTCSVPWAPPPAPVSPYSSTCTYGPLGWGPGPQHAPFWSTVPPPPLPPASIGRAV 1011
P + P P P P G P P T P P P
Sbjct: 760 TTPKEPAPTTPKEPAPTT-----------PKGTAPTTLKEPA-PTTPKKPAPK----ELA 803
Query: 1012 PQPKMESRGTPAGPPENVLPLSMAPPLSLGLPGHGAPQTEPTKVEVKPVPASPHPKHKVS 1071
P T + P P AP P AP T KP P +P +
Sbjct: 804 PTTTKGPTSTTSDKPAPTTPKETAPT----TPKEPAPTTPK-----KPAPTTPETPPPTT 854
Query: 1072 ALVQSPQMKALACVSAEGVTVEEPASERLKPETQETRPREKPPLPATKAVPTPR--QSTV 1129
+ V +P + E T+ + E + E P+ P VPT + +T
Sbjct: 855 SEVSTP------TTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATK 908
Query: 1130 PKLPAVHPARLRKLSFLPTPRT 1151
P++ + + TP T
Sbjct: 909 PEMTTTAKDKTTERDLRTTPET 930
Score = 85.9 bits (211), Expect = 3e-16
Identities = 185/795 (23%), Positives = 246/795 (30%), Gaps = 120/795 (15%)
Query: 654 PPVDAVPSGPAPVDLALVDP----VPNDLTPVDPVLVKSRPTDPRRGAVSSALGGSAPQL 709
P VD SG D + P ++ P + ++P +PR ++ L
Sbjct: 217 PVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSL 276
Query: 710 LVESESLDPPKTIIPEVKEVVDSLKIESGTSATTHEARPRPLSLSEYRRRRQQRQAETEE 769
V E+ E KE + K T+ + + + S E + E
Sbjct: 277 TVNKETT-------VETKETTTTNK------QTSTDGKEKTTSAKE------TQSIEKTS 317
Query: 770 RSPQPPTGKWPSLPETPTGLADIPCLVIPPAPAKKTALQRSPETPLEICLVPVGPSPASP 829
PT K + PT A+ PA T + +P TP E PAS
Sbjct: 318 AKDLAPTSK---VLAKPTPKAE----TTTKGPALTTPKEPTPTTPKE---------PAST 361
Query: 830 SPEPPVSKPVASSPTEQVPSQEMPLLARPSP-------PVQSVSPAVPTPPSMSAAL--- 879
+P+ P + S+PT P + P + +P P + PA TP +
Sbjct: 362 TPKEPTPTTIKSAPT--TPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKE 419
Query: 880 PFPAGGLGMPPSLPPPPLQPPSLPLSMGPVLPDPFTHYAPLPSWPCYP-HVSPSGYPCLP 938
P P P + P P P P P P T P P+ P P + P P
Sbjct: 420 PAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP 479
Query: 939 --PPPTVPLVSGTPGAYAVPPTCSVPWAP-------PPAPVSPYSSTCTYGPLGW-GPGP 988
P PT P PT AP P P P +T P P P
Sbjct: 480 KEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAP 539
Query: 989 QHAPFWSTVPPPPLPPASIGRAVPQPKMESRGTPAGPPENVLPLSMAPPLSLGLPGHGAP 1048
T P P P + A PK + TP P P AP P AP
Sbjct: 540 TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTT-PKEPAPT----TPKEPAP 594
Query: 1049 QTEPTKVEVKPVPASPHPKHKVSALVQSPQMKALACVSAEGV---TVEEPA---SERLKP 1102
T TK P P P +P K L + E + T E+PA E L P
Sbjct: 595 TT--TKKPAPTTPKEPAPTTPKETAPTTP--KKLTPTTPEKLAPTTPEKPAPTTPEELAP 650
Query: 1103 ETQE----TRPREKPPLPATKAVP-TPRQ--STVPKLPA----VHPARLRKLSFLPTPRT 1151
T E T P E P A P TP++ T PK PA PA PT
Sbjct: 651 TTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPT-TP 709
Query: 1152 QGSEDVVQAFISEIGIEASDLSSLLEQFEKSEAKKECPPPAPADSLAVGNSGGVDIPQEK 1211
+G+ + + L K C PAP + P+E
Sbjct: 710 KGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPT----TPKEP 765
Query: 1212 RPLDRLQAPELANVAGLTPPATPPHQLWKPLAAVSLLAKAKSPKSTAQEGTLKPEGVTEA 1271
P + A TP T P L +P K +PK A T P T
Sbjct: 766 APTTPKEP------APTTPKGTAPTTLKEPAPTT---PKKPAPKELAPTTTKGPTSTTSD 816
Query: 1272 KHPAAVRLQEGVHGPSRVHVGSGDHDYCVRSRTPPKKMPALVIPEVGSRWNVKRHQDITI 1331
K + P + T PKK PA PE + T
Sbjct: 817 KPAPTTPKETAPTTPKE------------PAPTTPKK-PAPTTPETPPPTTSEVSTPTTT 863
Query: 1332 KPVLSLGPAAPPPPCIAASREPLDHRTSSEQADPSAPCLAPSSLLSPEASPCRNDMNT-- 1389
K ++ +P S EP + +P P + PE + D T
Sbjct: 864 KEPTTI-HKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTER 922
Query: 1390 --RTPPEPSAKQRSM 1402
RT PE + M
Sbjct: 923 DLRTTPETTTAAPKM 937
Score = 38.5 bits (88), Expect = 0.055
Identities = 24/69 (34%), Positives = 37/69 (53%)
Query: 1437 TSEASSSSSSSSSSSRSRSRSLSPPHKRWRRSSCSSSGRSRRCSSSSSSSSSSSSSSSSS 1496
+ +A S +S + + RS PP+K+ + S + S S + SSSSSSSSSS
Sbjct: 116 SKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSSS 175
Query: 1497 SSSRSRSRS 1505
SS+ + +S
Sbjct: 176 SSTIRKIKS 184
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 107 bits (266), Expect = 1e-22
Identities = 164/676 (24%), Positives = 237/676 (35%), Gaps = 120/676 (17%)
Query: 654 PPVDAVPSGPAPVDLALVDPVPNDLTPVDPVLVKSRPTDPRRGAVSSALGGSAPQLLVES 713
PP VP P A V VP + + V V P P P++L
Sbjct: 10455 PPTKVVPRKEPP---AKVPEVPKKIVVEEKVRVPEEPRVPPT---------KVPEVL--- 10499
Query: 714 ESLDPPKTIIPEVKEVVDSLKIESGTSATTHEARPRPLSLSEYRRRRQQRQAETEERSPQ 773
PPK ++PE K V K EA ++ E++ P
Sbjct: 10500 ----PPKEVVPEKKVPVPPAKKPEAPPPKVPEA---------------PKEVVPEKKVPV 10540
Query: 774 PPTGKWPSLPETPTGLADIPCLVIPPA-------PAKKTALQRSPETPLEICLVPVGPSP 826
PP K P +P PT + ++P +P P ++ PE P E+ VP P
Sbjct: 10541 PPPKK-PEVP--PTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEV--VPEKKVP 10595
Query: 827 ASPSPEPPVSK-PVASSPTEQVPSQEMPLLARPSPPVQSVSPAVPTPPSMSAALPFPAGG 885
A+P +P V+ V +P E VP +++P+ PP + P P A+P
Sbjct: 10596 AAPPKKPEVTPVKVPEAPKEVVPEKKVPV----PPPKKPEVPPTKVPEVPKVAVPEKK-- 10649
Query: 886 LGMPPSLPPPPLQPPSLPLSMGPVLPDPFTHYAPLPSWPCYPHVSPSGYPCLPPPPTVPL 945
+P ++PP P PP P+ F + V P PP TVP
Sbjct: 10650 --VPEAIPPKPESPP----------PEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPP 10697
Query: 946 VSGTPGAYAVPPTCSVPWAPP------PAPVSPYSSTCTYGPLGWGPGPQHAPFW--STV 997
P A P PP P V P P P P V
Sbjct: 10698 KKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVV 10757
Query: 998 PP--------PPLPPASIGRAVPQPKMESRGTPAGP-PENVLPLSMAPPLSLGLPGHGAP 1048
P P +PPA + +P +E + PA P PE PP P AP
Sbjct: 10758 PEKKVAVPKKPEVPPAKVPEVPKKPVLEEK--PAVPVPERA---ESPPPEVYEEPEEIAP 10812
Query: 1049 QTEPTKVEVKPVPASPHPKHKVS--ALVQSP-----QMKALACVSAEGVTVEEPASERLK 1101
+ E E KPVP + + +V A+ + P + K E +EP E++
Sbjct: 10813 EEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVI 10872
Query: 1102 PETQETRPREKPPLPAT------------KAVPTPRQSTVPKLPAVHPARLRKLSFLPTP 1149
E + +PR PP PA KA+P + P++P K+ P
Sbjct: 10873 -EKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVP-------EKVELTPL- 10923
Query: 1150 RTQGSEDVVQAFISEIGIEASDLSSLLEQFEKSEAKKECPPPAPADSLAVGNSGGVDIPQ 1209
+ G E V+ + E E + L K ++E P L V P
Sbjct: 10924 KVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEE--PKVEPKKLEKVKKPAVPEPP 10981
Query: 1210 EKRPLDRLQAPELANVAGLTPPATPPHQLWKPLAAVSLLAKAKSPKSTAQEGTLKPEGVT 1269
+P++ ++ P + P T ++ KP A+ L A PK A+ T+KP V
Sbjct: 10982 PPKPVEEVEVPTVTKRERKIPEPTKVPEI-KP--AIPLPAPEPKPKPEAEVKTIKPPPVE 11038
Query: 1270 EAKHPAAVRLQEGVHG 1285
P A + V G
Sbjct: 11039 PEPTPIAAPVTVPVVG 11054
Score = 99.8 bits (247), Expect = 2e-20
Identities = 188/876 (21%), Positives = 305/876 (34%), Gaps = 166/876 (18%)
Query: 599 PVLAGPVPVDPGLVDLASTSSELVEPLPAEPVLINPVLADSAAVDPAVVPISDNLPPVDA 658
P+ +P +P ++ E V P P P +I + ++ P VP PP
Sbjct: 10245 PISEEEIPEEPPSIE----EVEEVAP-PRVPEVIKKAVPEA----PTPVPKKVEAPPAKV 10295
Query: 659 ---VPSGPAPVDLALVDPVPNDLTPVDPVLVKSRPTDPRRGAVSSALGGSAPQ------- 708
+P PV + + P + V + + + P++ AV A G + +
Sbjct: 10296 SKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPKKEAVPPAKGRTVLEEKVSVAF 10355
Query: 709 ----LLVESESLDPPKTIIPEVKEVVDSLKIESGTSATTHEARPRPLSLSEYRRRRQQR- 763
++ E L+ + + E+ E + ++E + L ++R + R
Sbjct: 10356 RQEVVVKERLELEVVEAEVEEIPEEEEFHEVEEYFEEGEFHEVEEFIKLEQHRVEEEHRV 10415
Query: 764 -------------QAETEERSPQPPTGKW-------PSLPET--------PTGLADIPCL 795
+ E E+ PP G P P T P + ++P
Sbjct: 10416 EKVHRVIEVFEAEEVEVFEKPKAPPKGPEISEKIIPPKKPPTKVVPRKEPPAKVPEVPKK 10475
Query: 796 VIPPAPAKKTALQRSPETPLEICLVPVGPSPASPSPEPPVSKP------VASSPTEQVPS 849
++ + R P T + L P P P PP KP V +P E VP
Sbjct: 10476 IVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVPE 10535
Query: 850 QEMPLLARPSPPVQSVSPAVPTPPSMSAALPFPAGGLGMPPSLPP-PPLQPPSLPLSMGP 908
+++P+ PP + P P AA+P +P ++PP P PP +P +
Sbjct: 10536 KKVPV----PPPKKPEVPPTKVPEVPKAAVPEKK----VPEAIPPKPESPPPEVPEAPKE 10587
Query: 909 VLPDPFTHYAPLPSWPCYPHVSPSGYPCLPPPPTVPLVSGTPGAYAVPPTCSVPWAPPPA 968
V+P+ AP P P V+P P P V P VP PP
Sbjct: 10588 VVPEKKVPAAP----PKKPEVTPVKVPEAPK--------------EVVPEKKVPVPPPKK 10629
Query: 969 PVSPYSSTCTYGPLGWGPGPQHAPFWSTVPPPPLPPASIGRAVPQPKMESRGTPAGPPEN 1028
P P P P VP +P + A+P PK ES
Sbjct: 10630 PEVP---------------PTKVP---EVPKVAVPEKKVPEAIP-PKPESPPPEVFEEPE 10670
Query: 1029 VLPLSMAPPLSLGLPGHGAPQTEPTKVEVKPVPASPHPKHKVSALV-QSPQMKALACVSA 1087
+ L P + P AP +V P P P+ K A+V + P++ +
Sbjct: 10671 EVALEEPPAEVVEEPEPAAPP------QVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEV 10724
Query: 1088 EGVTVEEPASERLKPETQETRPREKPPLPATKAVPTPRQSTVPKLPAVHPARLRKLSFLP 1147
V E + P+ E P + P +P K V ++ VPK P V PA++ ++ P
Sbjct: 10725 PKEVVPEKKVPLVVPKKPEAPPAKVPEVP--KEVVPEKKVAVPKKPEVPPAKVPEVPKKP 10782
Query: 1148 TPRTQGSEDVVQAFIS---EIGIEASDLS---SLLEQFEK-----SEAKKECPPPA---- 1192
+ + V + S E+ E +++ + + EK E + E PPPA
Sbjct: 10783 VLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEE 10842
Query: 1193 -----PADSLAVGNSGGVDIPQEKRPLDRLQAPELANVAGLTPPATPPHQLWKPLAAVSL 1247
P + V P+E P ++ P+L PPA P + + + +
Sbjct: 10843 PKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKA 10902
Query: 1248 LAKAKSPK--STAQEGTLKPEGVTEAKHPAAVRLQEGVHGPSRVHVGSGDHDYCVRSRTP 1305
+ K K P+ ++ L P V + L E P V ++
Sbjct: 10903 IPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEE----------VVLKSV 10952
Query: 1306 PKKMPALVIPEVGSRWNVKRHQDITIKPVLSLGPAAPPP--------PCIAASREPLDHR 1357
+K P P+V K+ + + KP + P PPP P + +
Sbjct: 10953 LRKRPEEEEPKV----EPKKLEKVK-KPAV---PEPPPPKPVEEVEVPTVTKRERKIPEP 11004
Query: 1358 TSSEQADPSAPCLAPSSLLSPEASPCRNDMNTRTPP 1393
T + P+ P AP PEA ++ T PP
Sbjct: 11005 TKVPEIKPAIPLPAPEPKPKPEA-----EVKTIKPP 11035
Score = 72.0 bits (175), Expect = 4e-12
Identities = 217/1001 (21%), Positives = 345/1001 (34%), Gaps = 130/1001 (12%)
Query: 430 PREVVEPVVPKEPQNPPANAAPGSQRARKGRK-----KKSKEQPAACVEGYARRLRSSSR 484
P E V + PK + PPA +R K K K + QP V + R+ +
Sbjct: 9673 PEEKVLKLKPKREEEPPAKVTEFRKRVVKEEKVSIEAPKREPQPIKEVTIMEEKERAYTL 9732
Query: 485 GQSTVGTEVTSQVDNLQKQPQEELQKESGPLQGKGKPRAWARAWAAALENSSPKNLERSA 544
+ V + + + ++ +E ++ +P + E + E
Sbjct: 9733 EEEAVSVQREEEYEEYEEYDYKEFEEY--------EPTEEYDQYEEYEEREYERYEEHEE 9784
Query: 545 GQSSPAKEGPLDLYPKLADTIQTNPIPTHLSLVDSA---QASPMPVDSVEADPTAVGPVL 601
+ P K P+ + P + + T P ++ A + P+P+ P P
Sbjct: 9785 YITEPEK--PIPVKPVPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEE 9842
Query: 602 AGPVPVDPGLVDLASTSSELV-EPLPAEPVLINPVLADSAAVDPAVVPISDNLPPVDA-- 658
V + + + E V EP P+ V+A+ + VP + PPV
Sbjct: 9843 PKKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAE----EKVPVPRKEVAPPVRVPE 9898
Query: 659 VPSGPAPVDLALVDPVPNDLTPVDPVLVKSRPTDPRRGAVSSALGGSAPQLLVESESLDP 718
VP P ++A + V +T V+ LV+ P + V+ +
Sbjct: 9899 VPKELEPEEVAFEEEV---VTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEV-- 9953
Query: 719 PKTIIPEVKEVVDSLKIESGTSATTHEARPRPLSLSEYRRRRQQRQAETEERSPQPPTGK 778
P+ +PE K+ V K + A E +P +++ + +PP K
Sbjct: 9954 PRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKP----------EEKVPVLIPKKEKPPPAK 10003
Query: 779 WPSLPETPTGLADIPCLVIPPAPAKKTALQRSPETPLEICLVPVGPSP----ASPSPEPP 834
P +P+ P +P V A + P+ P+ VPV P+P A P+ P
Sbjct: 10004 VPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPV-PAPKKVEAPPAKVPE 10062
Query: 835 VSKPVASSPTEQVPSQEMPLLARPSPPVQSVSPAVPTPPSMSAALPFPAGGLGMPPSLPP 894
V K + P E+ P+ + P P V VP P ALP L +P
Sbjct: 10063 VPKKLI--PEEKKPTPVPKKVEAPPPKVPKKREPVPVP----VALPQEEEVLFEEEIVPE 10116
Query: 895 PPLQPPSLPLSMGPVLPDPFTHYAPLPS----WPCYPHVSPSGYPCLPPPPTVPLVSGTP 950
+ P VLP+ LP P + P P VP
Sbjct: 10117 EEVLPEE-----EEVLPE---EEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFV 10168
Query: 951 GAYAVPPTCSVPWAPPPAPVSPYSSTCTYGPLGWGPGPQHAPFWSTVPPPPLPPASIGRA 1010
V P P P PAPV T + P PP +P
Sbjct: 10169 PEEEVLPEVK-PKVPVPAPVPEIKKKVTEKKVV-------IPKKEEAPPAKVPE------ 10214
Query: 1011 VPQPKMESRGTPAGPPENVLPLSMAP-PLSLGLPGHGAPQTEPTKVEVKPVPASPHPKHK 1069
VP+ K+E + E VLP+ + P + P+ P+ EV+ V A P
Sbjct: 10215 VPK-KVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEV-APPRVPEV 10272
Query: 1070 VSALVQSPQMKALACVSAEGVTVEEPASERLKP---ETQETRPREKPPLPATKAVPTPRQ 1126
+ V V A V + E P + +E P + P +P K VP ++
Sbjct: 10273 IKKAVPEAPTPVPKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVP--KKVPE-KK 10329
Query: 1127 STVPKLPAVHPARLR-----KLSFLPTPRTQGSE----DVVQAFISEIGIEASDLSSLLE 1177
VPK AV PA+ R K+S E +VV+A + EI E + + E
Sbjct: 10330 VLVPKKEAVPPAKGRTVLEEKVSVAFRQEVVVKERLELEVVEAEVEEIP-EEEEFHEVEE 10388
Query: 1178 QFEKSEAKKECPPPAPADSLAVGNSGGVDIPQEKRPLDRLQAPELANVAGLTPPATPPHQ 1237
FE+ E E + V V+ + R ++ +A E V P PP
Sbjct: 10389 YFEEGEF-HEVEEFIKLEQHRVEEEHRVE--KVHRVIEVFEAEE---VEVFEKPKAPP-- 10440
Query: 1238 LWKPLAAVSLLAKAKSPKSTAQEGTLKPEGVTEAKHPAAVRLQEGVHGPSRVHVGSGDHD 1297
K + K P + P V E P + ++E V P
Sbjct: 10441 --KGPEISEKIIPPKKPPTKVVPRKEPPAKVPEV--PKKIVVEEKVRVPE---------- 10486
Query: 1298 YCVRSRTPPKKMPALVIPEVGSRWNVKRHQDITIKPVLSLGPAAPPPPCIAASREPLDHR 1357
R PP K+P ++ P+ V + + + P P APPP A +E + +
Sbjct: 10487 ---EPRVPPTKVPEVLPPK-----EVVPEKKVPVPPAKK--PEAPPPKVPEAPKEVVPEK 10536
Query: 1358 TSSEQADPSAPCLAPSSLLS-PEASPCRNDMNTRTPPEPSA 1397
P P + P+ + P+A+ + PP+P +
Sbjct: 10537 -KVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPES 10576
Score = 70.1 bits (170), Expect = 2e-11
Identities = 161/722 (22%), Positives = 242/722 (33%), Gaps = 100/722 (13%)
Query: 429 KPREVVEPVVPKEPQNPPANAAPGSQRARKGRKKKSKEQPAACVEGYARRLRSSSRGQST 488
K E+ E ++P P+ PP P RK K E P V R+ R T
Sbjct: 10441 KGPEISEKIIP--PKKPPTKVVP-----RKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPT 10493
Query: 489 VGTEVTSQVDNLQKQPQEELQKESGPLQGKGKPRAWARAWAAALENSSPKNLERSAGQSS 548
EV P+E + ++ P+ KP A A + P+
Sbjct: 10494 KVPEVLP--------PKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKK 10545
Query: 549 P------AKEGPLDLYP--KLADTIQTNPIPTHLSLVDSAQASPMPVDSVEADPTAVGPV 600
P E P P K+ + I P + V A +P V A P V
Sbjct: 10546 PEVPPTKVPEVPKAAVPEKKVPEAIPPKP-ESPPPEVPEAPKEVVPEKKVPAAPPKKPEV 10604
Query: 601 LAGPVPVDPGLVDLASTSSELVEPLPAEP------VLINPVLADSAAVDPAVVPISDNLP 654
VP P V ++ P P +P V P +A P +P P
Sbjct: 10605 TPVKVPEAPKEV---VPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESP 10661
Query: 655 PVDAVPSGPAPVDLALVDPVPNDLTPVDPVLVKSRPTDPRRGAVSSALGGSAPQLLVESE 714
P + P ++AL +P + +P P++ AP ++ +
Sbjct: 10662 PPEVFEE---PEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEK----KAPAVVAKKP 10714
Query: 715 SLDPPKTIIPEV-KEVVDSLKIESGTSATTHEARPRPLSLSEYRRRRQQRQAETEERSPQ 773
L P K +PEV KEVV K+ + P + E + + + P+
Sbjct: 10715 ELPPVK--VPEVPKEVVPEKKVPL---VVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPE 10769
Query: 774 PPTGKWPSLPETPTGLADIPCLVIPP-APAKKTALQRSPETPL---EICLVPVGPSPASP 829
P K P +P+ P L + P + +P A + + PE EI P P +
Sbjct: 10770 VPPAKVPEVPKKPV-LEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAE 10828
Query: 830 SPEPPVSKP-VASSPTEQVPSQEMPLLARPSPPVQSVSPAVPTPPSMSAALPFPAGGLGM 888
EP V P V P + +P +++P++ +P P P P + P +
Sbjct: 10829 EEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPP-------PKEPEPEKVIEKPK----L 10877
Query: 889 PPSLPPPPLQPPSLPLS--MGPVLPDPFTHYAPLPSWPCYPHVSPSGYP--------CLP 938
P PPPP PP + + + P P P ++P P LP
Sbjct: 10878 KPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLP 10937
Query: 939 ---PPPTVPLVSGT--------------PGAYAVPPTCSVPWAPPPAPVSPYSSTCTYGP 981
P P +V + P +VP PPP PV
Sbjct: 10938 ERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKR 10997
Query: 982 LGWGPGPQHAPFWSTVPPPPLPPASIGRAVPQPKMESR-GTPAGPPENVLPLSMAPPLSL 1040
P P P P P P P+PK E+ T PP P +A P+++
Sbjct: 10998 ERKIPEPTKVPEIKPAIPLPAPE-------PKPKPEAEVKTIKPPPVEPEPTPIAAPVTV 11050
Query: 1041 GLPGHGAPQTEPTKVEVKPV-PASPHPKHKVSALVQSPQMKALACVSAEGVTVEEPASER 1099
+ G A P + KP P PK K + +++ + K E E P + +
Sbjct: 11051 PVVGKKAEAKAPKEEAAKPKGPIKGVPK-KTPSPIEAERRKLRPGSGGEKPPDEAPFTYQ 11109
Query: 1100 LK 1101
LK
Sbjct: 11110 LK 11111
Score = 68.6 bits (166), Expect = 5e-11
Identities = 162/733 (22%), Positives = 247/733 (33%), Gaps = 136/733 (18%)
Query: 360 EIPVVVRQVSPGPRPVLLDDSLETSSALQLLMPTLESETEAA-VPKVTLCSEKEGLSLNS 418
E+ V + +P P + + + ++P E + VPK + EK + +
Sbjct: 10429 EVEVFEKPKAPPKGPEISEKIIPPKKPPTKVVPRKEPPAKVPEVPKKIVVEEK--VRVPE 10486
Query: 419 EEKLDSACL---LKPREVVE----PVVP-KEPQNPPANAAPGSQRARKGRK-----KKSK 465
E ++ + L P+EVV PV P K+P+ PP + +K K
Sbjct: 10487 EPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKKP 10546
Query: 466 EQPAACVEGYARRLRSSSRGQSTVGTEVTSQVDNLQKQPQEELQKESGPLQGKGKPRAWA 525
E P V + + + + S + + P+E + ++ P KP
Sbjct: 10547 EVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEV-- 10604
Query: 526 RAWAAALENSSPKNLERSAGQSSPAKEGPLDLYPKLADTIQTNPIPTHLSLVDSAQASPM 585
+P + + + P K+ P+ PK + T V +
Sbjct: 10605 ----------TPVKVPEAPKEVVPEKKVPVPP-PKKPEVPPTK--------VPEVPKVAV 10645
Query: 586 PVDSVEADPTAVGPVLAGPVPV---DPGLVDLASTSSELVE-PLPAEP--VLINPVLADS 639
P V P A+ P P P +P V L +E+VE P PA P V + P
Sbjct: 10646 PEKKV---PEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVP 10702
Query: 640 AAVDPAVVPISDNLPPV-------DAVPSGPAPVDL--------ALVDPVPNDLTPVDPV 684
PAVV LPPV + VP P+ + A V VP ++ P V
Sbjct: 10703 EKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKV 10762
Query: 685 LVKSRPTDPRRGAVS---SALGGSAPQLLVESESLDPPKTIIPEVKEVVDSLKIESGTSA 741
V +P P + P + V + PP + E +E+ +I
Sbjct: 10763 AVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAP---- 10818
Query: 742 TTHEARPRPLSLSEYRRRRQQRQAETEERSPQPPTGKWPSL--PETPTGLADIPCLVI-- 797
+P+ ++E A EE P K P + PE P P VI
Sbjct: 10819 ----EEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEK 10874
Query: 798 ----------PPAPAK--------------KTALQRSPETPLEICLVPVGPSPAS----- 828
PPAP K K + P+ P ++ L P+
Sbjct: 10875 PKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRK 10934
Query: 829 --PSPEP-PVSKPVASSPTEQVPSQEMPLLARPSPPVQSVSPAVPTPPSMSAALPFPAGG 885
P +P P + V S + P +E P + P + PAVP PP P P
Sbjct: 10935 LLPERKPEPKEEVVLKSVLRKRPEEEEPKV-EPKKLEKVKKPAVPEPPP-----PKPVEE 10988
Query: 886 LGMPP------SLPPPPLQP---PSLPLSMGPVLPDPFTHYAPLPSWPCYPHVSPSGYPC 936
+ +P +P P P P++PL P P + P P +P
Sbjct: 10989 VEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTP----- 11043
Query: 937 LPPPPTVPLVSGTPGAYAVPPTCSVPWAP-------PPAPVSPYSSTCTYGPLGWGPGPQ 989
+ P TVP+V A A + P P P+P+ G G P P
Sbjct: 11044 IAAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPSPIEAERRKLRPGSGGEKP-PD 11102
Query: 990 HAPFWSTVPPPPL 1002
APF + PL
Sbjct: 11103 EAPFTYQLKAVPL 11115
Score = 60.1 bits (144), Expect = 2e-08
Identities = 108/524 (20%), Positives = 180/524 (34%), Gaps = 87/524 (16%)
Query: 430 PREVVEPVVPKEPQNPPANAAPGSQRA---RKGRKKKSKEQPAAC--VEGYARRLRSSSR 484
P + V +P +P++PP + + + +PAA V ++ +
Sbjct: 10646 PEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKK 10705
Query: 485 GQSTVGTEVTSQVDNLQKQPQEELQKESGPLQGKGKPRAWARAWAAALENSSPKNLERSA 544
+ V + + + P+E + ++ PL KP A A PK +
Sbjct: 10706 APAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEA-----PPAKVPEVPKEVVPEK 10760
Query: 545 GQSSPAKEGPLDLYPKLADTIQTNPIPTHLSLVDSAQASPMPVDSVEADPTAVGPVLAGP 604
+ P K ++ P + P+ V + + P V +P + P
Sbjct: 10761 KVAVPKKP---EVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAP----- 10812
Query: 605 VPVDPGLVDLASTSSELVEPLPAEPVLINPVLADSAAVDPAVVPISDNLPPVDAVPSGPA 664
E + P +PV PV + +P V P + P +P
Sbjct: 10813 --------------EEEIAPEEEKPV---PVAEEE---EPEVPPPAVPEEPKKIIPEKKV 10852
Query: 665 PVDLALVDPVPNDLTP---VDPVLVKSRPTDPRRGAVSSALGGSAPQLLVESESLDPPKT 721
PV P P + P ++ +K RP P + QL + P K
Sbjct: 10853 PVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKP 10912
Query: 722 IIPEVKEVVDSLKIESGTSATTH---EARPRP----LSLSEYRRRRQQRQAETEERS--- 771
+PE E+ LK+ G E +P P + S R+R ++ + + E +
Sbjct: 10913 QVPEKVELTP-LKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEK 10971
Query: 772 ------PQPP-------------TGKWPSLPETPTGLADIPCLVIPPAPAKKTALQRSPE 812
P+PP T + +PE PT + +I + PAP K + +
Sbjct: 10972 VKKPAVPEPPPPKPVEEVEVPTVTKRERKIPE-PTKVPEIKPAIPLPAPEPKPKPEAEVK 11030
Query: 813 TPLEICLVPVGPSPASPSPEP---PVSKPVASSPTE-QVPSQEMPLLARPSPPVQSVSPA 868
T + P P P P P PV+ PV E + P +E A+P P++ V
Sbjct: 11031 T--------IKPPPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEA---AKPKGPIKGVPKK 11079
Query: 869 VPTPPSMSAALPFPAGGLGMPPSLPPPPLQPPSLPLSMGPVLPD 912
P+P P G PP P Q ++PL + D
Sbjct: 11080 TPSPIEAERRKLRPGSGGEKPPDEAPFTYQLKAVPLKFVKEIKD 11123
Score = 45.1 bits (105), Expect = 6e-04
Identities = 45/171 (26%), Positives = 60/171 (35%), Gaps = 11/171 (6%)
Query: 811 PETPLEICLVPVGPSPASPSPEPPVSKPVASSPTEQVPSQEMPL-LARPSPPVQSVSPAV 869
PE P + V P P EPP K V P + VP ++ P+ + + P P V
Sbjct: 9289 PELPEKPAPEEVAPVPIPKKVEPPAPK-VPEVPKKPVPEEKKPVPVPKKEPAAPPKVPEV 9347
Query: 870 PTPPSMSAALPFPAGGLGMPPSLPPPPLQPPSLPLSMGPVL------PDPFTHYAPLPSW 923
P P +P P P P +Q + ++ P P P
Sbjct: 9348 PKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAVPEIPKKKV 9407
Query: 924 PCYPHVSPSGYPCLPPPPTVPLVSGTP---GAYAVPPTCSVPWAPPPAPVS 971
P P +PPPP VP + P AVP + PP A VS
Sbjct: 9408 PEERKPVPRKEEEVPPPPKVPALPKKPVPEEKVAVPVPVAKKAPPPRAEVS 9458
Score = 44.3 bits (103), Expect = 0.001
Identities = 57/227 (25%), Positives = 84/227 (37%), Gaps = 26/227 (11%)
Query: 705 SAPQLLVESESLDPPKTIIPEV-KEVVDSLKIESGTSATTHEARPRPLSLSEYRRRRQQR 763
S ++ S + + +PEV KE+V KI S E P+ L E +
Sbjct: 9243 SEEKMFFASHTEEEVSVTVPEVQKEIVTEEKIHVAISKRV-EPPPKVPELPEKPAPEEVA 9301
Query: 764 QAETEERSPQPPTGKWPSLPETPTGLADIPCLVIPPAPAKKTALQRSPETPLEICLVPVG 823
++ +PP K P +P+ P P P P K+ P P ++ VP
Sbjct: 9302 PVPIPKKV-EPPAPKVPEVPKKPVPEEKKPV----PVPKKE------PAAPPKVPEVPKK 9350
Query: 824 PSPASPSPEPPVSKPVASSPTEQVPSQEMPLLARPSPPV-----QSVSPAVPTPPSMSAA 878
P P P P K A P +VP + ++ + +S PAVP P
Sbjct: 9351 PVPEEKIPVPVAKKKEA--PPAKVPEVQKGVVTEEKITIVTQREESPPPAVPEIPKKK-- 9406
Query: 879 LPFPAGGLGMPPSLPPPPLQPPSLPLSMGP----VLPDPFTHYAPLP 921
+P + PPP + P+LP P +P P AP P
Sbjct: 9407 VPEERKPVPRKEEEVPPPPKVPALPKKPVPEEKVAVPVPVAKKAPPP 9453
Score = 44.3 bits (103), Expect = 0.001
Identities = 66/244 (27%), Positives = 84/244 (34%), Gaps = 58/244 (23%)
Query: 939 PPPTVPLVSGTPGAYAVPPTCSVPWAPPPAPVSPYSSTCTYGPLGWGPGPQHAPFWSTVP 998
PPP VP + P V P PPAP P VP
Sbjct: 9284 PPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVP-----------------------EVP 9320
Query: 999 PPPLPPASIGRAVPQPKMESRGTPAGP-------PENVLPLSM-----APPLSLGLPGHG 1046
P+P + VP PK E P P PE +P+ + APP + G
Sbjct: 9321 KKPVPEEK--KPVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKG 9378
Query: 1047 APQTEP----TKVEVKPVPASPH-PKHKVSALVQSPQMKALACVSAEGVTVEEPASERLK 1101
E T+ E P PA P PK KV P+ + E E P ++
Sbjct: 9379 VVTEEKITIVTQREESPPPAVPEIPKKKV------PEERKPVPRKEE----EVPPPPKVP 9428
Query: 1102 PETQETRPREK--PPLPATKAVPTPRQSTVPKLPAVHPARL---RKLSFLPTPRTQGSED 1156
++ P EK P+P K P PR + V K V R KLSF R + +
Sbjct: 9429 ALPKKPVPEEKVAVPVPVAKKAPPPR-AEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRH 9487
Query: 1157 VVQA 1160
V A
Sbjct: 9488 EVSA 9491
Score = 43.5 bits (101), Expect = 0.002
Identities = 61/220 (27%), Positives = 83/220 (37%), Gaps = 40/220 (18%)
Query: 619 SELVEPLPAEPVLINPVLADSAAVDPAVVPISDNLPPVDAVPSGPAPVDLALVDPVPNDL 678
S+ VEP P P L + A P + P V VP P P + V PVP
Sbjct: 9279 SKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPV-PVPKK- 9336
Query: 679 TPVDPVLVKSRPTDPRRGAVSSALGGSAPQLLVESESLDPPKTIIPEV-KEVVDSLKIES 737
+P P P++ + P + + + P K +PEV K VV KI
Sbjct: 9337 ---EPAAPPKVPEVPKKPVPEEKI----PVPVAKKKEAPPAK--VPEVQKGVVTEEKI-- 9385
Query: 738 GTSATTHEARPRPLSLSEYRRRRQQRQAETEERSPQPPTGKWPSLPETPTGLADIPCLVI 797
T T E P P ++ E +++ EER P P K +P P +P L
Sbjct: 9386 -TIVTQREESPPP-AVPEIPKKK-----VPEERKPVP--RKEEEVPPPP----KVPALPK 9432
Query: 798 PPAPAKKTALQRSPETPLEICLVPVGPSPASPSPEPPVSK 837
P P +K A VPV + +P P VSK
Sbjct: 9433 KPVPEEKVA-------------VPVPVAKKAPPPRAEVSK 9459
Score = 38.1 bits (87), Expect = 0.072
Identities = 31/91 (34%), Positives = 38/91 (41%), Gaps = 20/91 (21%)
Query: 822 VGPSPASPSPEPPVSKPVASSPTEQVPSQEMPLLARPSP----------PVQSVSPA--V 869
+ P P S SP PP A +Q PS P+ PSP PV+SVSPA +
Sbjct: 257 IPPKPKSRSPTPPSIAAKAQLARQQSPS---PIRHSPSPVRHVRAPTPSPVRSVSPAARI 313
Query: 870 PTPPSMSAALPF-----PAGGLGMPPSLPPP 895
T P S P A + P +PPP
Sbjct: 314 STSPIRSVRSPLLMRKTQASTVATGPEVPPP 344
Score = 38.1 bits (87), Expect = 0.072
Identities = 114/562 (20%), Positives = 204/562 (36%), Gaps = 79/562 (14%)
Query: 141 ENLSPFDSIPDSELLVSPREGSSLHKLLTLSRTPPERDLITPVDPLGPSTGSSRGSGVEM 200
E + P P E+ +P+E K+ PP++ +TPV P ++
Sbjct: 10568 EAIPPKPESPPPEVPEAPKEVVPEKKV---PAAPPKKPEVTPVKV--PEAPKEVVPEKKV 10622
Query: 201 SLPDPSWDFSPPSFL-ETSSPKLPSWRPPRSRPRWGQSPPPQQRSDGEEEEEVASFSGQI 259
+P P PP+ + E +P + P + P +SPPP+ EE EEVA
Sbjct: 10623 PVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVF---EEPEEVA------ 10673
Query: 260 LAGELDNCVSSIPDFPMHLACPE--EEDKATAAEMAVPAAGDESISSLSELVRAMHPYCL 317
L+ + + + P A P+ K E PA ++ EL P
Sbjct: 10674 ----LEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAV----VAKKPELPPVKVPEVP 10725
Query: 318 PNLTHLASLEDELQEQPDDLTLPEGCVVLEIVGQAATA-GDDLEIPVVVRQVSPGPRPVL 376
+ + + ++P+ V E+V + A E+P +V P+ +
Sbjct: 10726 KEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPA--KVPEVPKKPV 10783
Query: 377 LDD--SLETSSALQLLMPTLESETEAAVPKVTLCSEKEGLSLNSEEKLDSACLLKPREVV 434
L++ ++ + P + E E P+ + E+E +EE + EV
Sbjct: 10784 LEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEE--------EEPEVP 10835
Query: 435 EPVVPKEPQN-PPANAAPGSQRARKGRKKKSKEQPAACVEGYARRLRSSSRGQSTVGTEV 493
P VP+EP+ P P ++ K + +P +E + R + +V
Sbjct: 10836 PPAVPEEPKKIIPEKKVPVIKKPEAPPPK--EPEPEKVIEKPKLKPRPPPPPPAPPKEDV 10893
Query: 494 TSQVDNLQ--------KQPQEELQKESGPLQGKGKPRAWARAWAAALENSSPKNLERSAG 545
++ L+ ++PQ + E PL+ G + + + + +S
Sbjct: 10894 KEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVL 10953
Query: 546 QSSPAKEGPLDLYPKLADTIQTNPIPTHLSLVDSAQASPMPVDSVEA-----------DP 594
+ P +E P + PK + ++ +P P PV+ VE +P
Sbjct: 10954 RKRPEEEEP-KVEPKKLEKVKKPAVP--------EPPPPKPVEEVEVPTVTKRERKIPEP 11004
Query: 595 TAVGPV-----LAGPVPVDPGLVDLASTSSELVEPLP---AEPVLINPVLADSAAVDPAV 646
T V + L P P ++ + VEP P A PV + PV+ A
Sbjct: 11005 TKVPEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTV-PVVGKKAEAKAPK 11063
Query: 647 VPISDNLPPVDAVP-SGPAPVD 667
+ P+ VP P+P++
Sbjct: 11064 EEAAKPKGPIKGVPKKTPSPIE 11085
Score = 36.6 bits (83), Expect = 0.21
Identities = 33/118 (27%), Positives = 48/118 (40%), Gaps = 7/118 (5%)
Query: 1437 TSEASSSSSSSSSSSRSRSRSLSPPHKRWRRSSCSSSGRSRRCSSSSSSSSSSSSSSSSS 1496
+ A SSSS+S R RSLSP + R S RSR + + S
Sbjct: 32254 SKHAQRESSSSASRLLRRRRSLSPTYIELMR-PVSELIRSR---PQPAEEYEDDTERRSP 32309
Query: 1497 SSSRSRSRSPSP---RRRSDRRRRYSSYRSHDHYQRQRVLQKERAIEERRVVFIGKIP 1551
+ R+R RSPSP R R R + + Y+ + K + ER+ + + P
Sbjct: 32310 TPERTRPRSPSPVSSERSLSRFERSARFDIFSRYESMKAALKTQKTSERKYEVLSQQP 32367
Score = 35.8 bits (81), Expect = 0.36
Identities = 76/343 (22%), Positives = 130/343 (37%), Gaps = 82/343 (23%)
Query: 998 PPPPLPPASIGRAVPQPKMES-RGTPAGPPENVLPLSMAPPLSLGL----PGHGAPQTEP 1052
PPPP + + +P +E T E + ++ P +S + P Q E
Sbjct: 9175 PPPP-------KVIKKPVIEKIEKTSRRMEEEKVQVTKVPEVSKKIVPQKPSRTPVQEEV 9227
Query: 1053 TKVEVKPVPA------------SPHPKHKVSALVQSPQMKALACVSAEGVTVEEPASERL 1100
+V+V V + H + +VS V Q + V+ E + V S+R+
Sbjct: 9228 IEVKVPAVHTKKMVISEEKMFFASHTEEEVSVTVPEVQKEI---VTEEKIHVA--ISKRV 9282
Query: 1101 KPETQETRPREKP------PLPATKAV--PTPRQSTVPKLPA--------------VHPA 1138
+P + EKP P+P K V P P+ VPK P P
Sbjct: 9283 EPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAAPP 9342
Query: 1139 RLRKLSFLPTPRTQ------GSEDVVQAFISEI--GIEASDLSSLLEQFEKSEAKKECPP 1190
++ ++ P P + ++ A + E+ G+ + +++ Q ++E PP
Sbjct: 9343 KVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQ------REESPP 9396
Query: 1191 PAPADSLAVGNSGGVDIPQEKRPLDRL--QAPELANVAGLTPPATPPHQLWKPLAAVSLL 1248
P AV +P+E++P+ R + P V L P ++ P V +
Sbjct: 9397 P------AVPEIPKKKVPEERKPVPRKEEEVPPPPKVPALPKKPVPEEKVAVP---VPVA 9447
Query: 1249 AKAKSPKSTAQEGTLKPEGVTEAKHPAAVRLQEGVHGPSRVHV 1291
KA P++ + T+ V E + A +L V P RV V
Sbjct: 9448 KKAPPPRAEVSKKTV----VEEKRFVAEEKLSFAV--PQRVEV 9484
Score = 35.0 bits (79), Expect = 0.61
Identities = 56/252 (22%), Positives = 102/252 (40%), Gaps = 41/252 (16%)
Query: 199 EMSLPDPSWDFSPPSFLETSSPKL-PSWRPPRSRPRWGQSPPPQQRSDGEEEEEVASFSG 257
++ +P P +PP+ + KL P + P P+ ++PPP+ E
Sbjct: 10044 KVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREP--------- 10094
Query: 258 QILAGELDNCVSSIPDFPMHLACPEEEDKATAAEMAVPAAGDESISSLSELVRAMHPYCL 317
P+ +A P+EE+ E+ VP +E + E V L
Sbjct: 10095 ----------------VPVPVALPQEEEVLFEEEI-VP---EEEVLPEEEEVLPEEEEVL 10134
Query: 318 PNLTHLASLEDELQEQPDDLTLPEGCVVLEIVGQAATAGDDLEIPVVVRQVSPGPRPVLL 377
P + E+E+ + +++ E E V + + E+ V+ P P PV
Sbjct: 10135 PEEEEVLPEEEEIPPEEEEVPPEE-----EYVPEEEEFVPEEEVLPEVKPKVPVPAPV-- 10187
Query: 378 DDSLETSSALQLLMPTLESETEAAVPKVTLCSEKEGLSLNSEEK-LDSACLLKPREVVEP 436
+ + + ++++P E A VP+V E++ + L EE+ L +P E EP
Sbjct: 10188 PEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEKRIILPKEEEVLPVEVTEEPEE--EP 10245
Query: 437 VVPKE-PQNPPA 447
+ +E P+ PP+
Sbjct: 10246 ISEEEIPEEPPS 10257
Score = 32.3 bits (72), Expect = 3.9
Identities = 28/88 (31%), Positives = 39/88 (44%), Gaps = 17/88 (19%)
Query: 999 PPPLPPASIGRAVPQPKMESRGTPAGPPENVLPLSMAPPLSLGLPGHGAPQTEPTKVEV- 1057
PP +P + VP P M R A PPE + P+ +APP+ L LP + P ++EV
Sbjct: 8934 PPDIPDSR----VPIPTMPIR---AVPPEEIPPV-VAPPIPLLLPTPEEKKPPPKRIEVT 8985
Query: 1058 --------KPVPASPHPKHKVSALVQSP 1077
K V A P +V+ P
Sbjct: 8986 KKAVKKDAKKVVAKPKEMTPREEIVKKP 9013
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 105 bits (263), Expect = 3e-22
Identities = 159/623 (25%), Positives = 217/623 (34%), Gaps = 109/623 (17%)
Query: 594 PTAVGPVLAGPVPVDPGLVDLASTSSELVEPLPAEPVLINPVLADSAAVDPAVVPISDNL 653
P P +P + G LA+ + L A P+L N LA ++ P + P S
Sbjct: 478 PAVQLPQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHS-GA 536
Query: 654 PPVDAVPSGPAPVDLALVDPVPNDLTPVDPVLVKSRPTDPRRGAVSSALGG-----SAPQ 708
+ + P V + +P L + +S+P P A ++ L G SA
Sbjct: 537 HSAHILSAAPIQVGQPALFQMPVSLA-AGSLPTQSQPA-PAGPAATTVLQGVTLPPSAVA 594
Query: 709 LLVESESLDPPKTIIPEVKEVVDSLKIESGTSATTHEARPRPLSLSEYRRRRQQRQAETE 768
+L + L P T E L ++ A + P PL L QQ QA+
Sbjct: 595 MLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGL-------QQPQAQQP 647
Query: 769 ERSPQPPTGKWP--SLPETPTGLADIPCLVI--PPAPAKKTAL------------QRS-- 810
++P P P + P+ GLA P ++ P A TA+ +RS
Sbjct: 648 PQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQ 707
Query: 811 ------PETPLEICLVPVGPSPAS-PSPEPPVSKPVASSP------TEQVPSQEMPLLAR 857
P + ++ P PA P+P PV+K P P+ ++P A
Sbjct: 708 PLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAP 767
Query: 858 PSPPVQSVSPAVPTPPSMSAALPFPAGGLGMPPSLPPPPLQPPSLPLSMGPVLPDPFTHY 917
P S SP++P + + P+ PPS PP Q S P S P+
Sbjct: 768 LKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPL-------- 819
Query: 918 APLPSWPCYPHVSPSGYPCLPP--PPTVPLVSGTPGAYAVPPTCSVPWAPPPAPVSPYSS 975
+PC PP PPT+P + VPP S P P P P
Sbjct: 820 ----------------HPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQP--- 860
Query: 976 TCTYGPLGWGPGPQHAPFWSTVPPPP-LPPASIGRAVPQPKMESRGTPAG---------P 1025
PL PQ P +PP P LPP+S AV S PA P
Sbjct: 861 -----PL----RPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFP 911
Query: 1026 PENVLPLSMAPPLSLGL-PGHGAPQTEPTK---VEVKPVPASPHPKHKVSALVQSPQMKA 1081
P S PP +L L P AP P + + P PA P PK + Q P
Sbjct: 912 PSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGII 971
Query: 1082 LACVSAEGVTVEEPASERLKPETQET--------RPREKPPLPATKAVPTPRQST--VPK 1131
L A G S L P T P P P+ P P +T P
Sbjct: 972 LQ-NKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPL 1030
Query: 1132 LPAVHPARLRKLSFLPTPRTQGS 1154
LPA + A L L + S
Sbjct: 1031 LPAENKAFASNLPTLNVAKAASS 1053
Score = 79.7 bits (195), Expect = 2e-14
Identities = 223/917 (24%), Positives = 300/917 (32%), Gaps = 227/917 (24%)
Query: 564 TIQTNPIPTHLSLVDSAQASPMPVDSVEADPTAVG---PVLAGPVPVDPGLVDLAS---- 616
T QT L L + P D A PT G V AGP + PG DL
Sbjct: 114 TEQTLEAEAELDLGPFQLPTLQPADG-GAGPTGAGGAAAVAAGPQALFPGSTDLLGLQGP 172
Query: 617 ----TSSELVEP-------LPAEPVLINPVLADSAAVDPAVVPISDNLPPVDAVPSGPAP 665
T LV P L +P L PV + + P +P LP + P G
Sbjct: 173 PTVLTHQALVPPQDVVNKALSVQPFL-QPVGLGNVTLQP--IPGLQGLP--NGSPGGATA 227
Query: 666 VDLALV------DPVPNDLTPVDPVLVKSRPTDPRRGAVSSALGGSAPQLLV------ES 713
L L PV TP +L K P G ++SA G S P L +
Sbjct: 228 ATLGLAPIQVVGQPVMALNTPTSQLLAKQVPVS---GYLASAAGPSEPVTLASAGVSPQG 284
Query: 714 ESLDPPKTIIPEVKEVVDSLKIESGT---SATTHEARPRPLSLSEYRRRRQQRQAETEER 770
L K + V ++ + G SA T +PL+++
Sbjct: 285 AGLVIQKNLSAAVATTLNGNSVFGGAGAASAPTGTPSGQPLAVA---------------- 328
Query: 771 SPQPPTGKWPSLP-------ETPTGLADIPCLVIPP----------APAKKT-------- 805
P G P +P TPT + P V+PP APA T
Sbjct: 329 ---PGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLYQLTPKPFAPAGATLTIQGEPG 385
Query: 806 ALQRSPETPLEICLVPVG-----------PSPA---------------SPSPEPP--VSK 837
AL + P+ P + + G P+PA + P+PP +SK
Sbjct: 386 ALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGAAPPQPPGALSK 445
Query: 838 PVASSPTEQ-----VPSQEMPLLARPSPPVQSVSPAVPTPPSMSAALPFPAGGLGMPPSL 892
P++ Q +P+Q M L + + +PAV P +SA LP GG + +
Sbjct: 446 PMSVHLLNQGSSIVIPAQHM--LPGQNQFLLPGAPAVQLPQQLSA-LPANVGGQILAAAA 502
Query: 893 PP--------PPLQPPSL--PLSMGPVL-PDPFTHYAPLPSWPCYPHVSPSGYPCLPPPP 941
P P L +L PLS+GPVL P H A + S
Sbjct: 503 PHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSAHILS------------------- 543
Query: 942 TVPLVSGTPGAYAVPPTC---SVPWAPPPAPVSPYSSTCTYGPLGWGPGPQHAPFWSTVP 998
P+ G P + +P + S+P PAP P ++T G P A P
Sbjct: 544 AAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTL----PPSAVAMLNTP 599
Query: 999 P----PPLPPASIGRAVPQPKMESRGTPAGPPENVLPLSMAPPLSLGLPGHGAPQTEPTK 1054
P P A+ G A P ++ P PP PL PL L P P PT
Sbjct: 600 DGLVQPATPAAATGEAAPVLTVQP--APQAPPAVSTPL----PLGLQQPQAQQPPQAPTP 653
Query: 1055 VEVKPVPAS-PHPKHKVSA------LVQSPQMKALACVSAEGVTVEEPASERLKPETQET 1107
P A+ P P +++ L Q P A ++ + + + P +P + E
Sbjct: 654 QAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEG 713
Query: 1108 RPREKPPLPATKAVPTPRQSTVPKLPAVHPARLRKLSFLPTPRTQGSE---DVVQAFISE 1164
P P + P P Q P P A L + P +Q S + A
Sbjct: 714 -PHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQA----PDSQASPAPAPQIPAAAPL 768
Query: 1165 IGIEASDLSSLLEQFEKSEAKK-ECPPPAPADSLAVGNSGGVDIPQEKRPLDRLQAPE-- 1221
G S SL Q ++ P P S V P + PL P+
Sbjct: 769 KGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAP 828
Query: 1222 --------LANVAGLTPPATPPHQLWKPLAAVSLLAKAKSPKSTAQEGTLKPEGVTEAKH 1273
+ N G+ PPA+ P A P+S EG L P A H
Sbjct: 829 PTLPGIFVIQNQLGVPPPASNPAP-----TAPGPPQPPLRPQSQPPEGPLPP-----APH 878
Query: 1274 PAAVRLQEGVHGPSRVHVGSGDHDYCVRSRTP---PKKMPALVIPEVGSRWNVKRHQDIT 1330
V S SR P P P G H+ T
Sbjct: 879 LPPSSTSSAVASSSETS-----------SRLPAPTPSDFQLQFPPSQGP------HKSPT 921
Query: 1331 IKPVLSL--GPAAPPPP 1345
P L L PAAPPPP
Sbjct: 922 PPPTLHLVPEPAAPPPP 938
Score = 74.7 bits (182), Expect = 7e-13
Identities = 131/528 (24%), Positives = 177/528 (33%), Gaps = 89/528 (16%)
Query: 529 AAALENSSPKNLERSAGQSSPAKEGPLDLYPKLADTIQTNPIPTHLSLVDSAQASPMPVD 588
AAA ++P + A Q+ PA PL L + Q PT + +P P
Sbjct: 609 AAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSP 668
Query: 589 SVEADPTAVGPVLAGPVPVDPGLVDLASTSSELVEPLPAEPVLINPVLADSAAVD-PAVV 647
+ + P + VL P P + T L LP E P+ A+ + PA V
Sbjct: 669 GLASSPEKI--VLGQPPSATPTAI---LTQDSLQMFLPQERSQ-QPLSAEGPHLSVPASV 722
Query: 648 PISDNLPPVDAVPSGPAPVDLALVDPVPNDLTPVDPVLVKSRPTDPRRGAVSSALGGSAP 707
+S P D P+ P L P+ P P P + S+P
Sbjct: 723 IVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPA-----PQIPAAAPLKGPGPSSSP 777
Query: 708 QLLVESESLDPPKTIIPEVKEVVDSLKIESGTSATTHEARP--RPLSLSEYRRRRQQRQA 765
L ++ D P P H RP RP S R + R
Sbjct: 778 SLPHQAPLGDSPHLPSP-------------------HPTRPPSRPPS----RPQSVSRPP 814
Query: 766 ETEERSPQPPTGKWPSLPETPTGLADIPCLVIPPAPAKKTALQRSPETPLEICLVPVGPS 825
P PP P P T G+ I + P PA P+
Sbjct: 815 SEPPLHPCPP----PQAPPTLPGIFVIQNQLGVPPPAS-------------------NPA 851
Query: 826 PASPSPEPPVSKPVASSPTEQVPSQEMPLLARPSPPVQSVSPAVPTPPSMSAALPFPAGG 885
P +P P P +P + P E PL P P S S AV + S+ LP P
Sbjct: 852 PTAPGPPQPPLRPQSQPP-------EGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPS 904
Query: 886 ---LGMPPSLPP--PPLQPPSLPLSMGPVLPDPFTHYAPLPSWPCYPHVSPSGYPCLPPP 940
L PPS P P PP+L L +P+P AP P P + + +P LP P
Sbjct: 905 DFQLQFPPSQGPHKSPTPPPTLHL-----VPEP---AAPPPPPPRTFQMVTTPFPALPQP 956
Query: 941 PTVPLVSGTPGAYAVPPTCSVPWAPPPAPVSPYSSTCTYGPLGWGPGPQHAPFWSTVPPP 1000
+ + VP + AP +P +ST + GPL P + S P
Sbjct: 957 KAL-----LERFHQVPSGIILQNKAGGAPAAPQTST-SLGPL---TSPAASVLVSGQAPS 1007
Query: 1001 PLPPASIGRAVPQPKMESRGTPAGPPENVLPLSMAPPLSLGLPGHGAP 1048
P A P P + P P EN S P L++ P
Sbjct: 1008 GTPTAPSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAKAASSGP 1055
Score = 33.1 bits (74), Expect = 2.3
Identities = 26/75 (34%), Positives = 36/75 (48%), Gaps = 3/75 (4%)
Query: 1449 SSSRSRSRSLSPPH---KRWRRSSCSSSGRSRRCSSSSSSSSSSSSSSSSSSSSRSRSRS 1505
SSS + + PPH K R + S + +SSS SSSSSSSS++SS +
Sbjct: 1228 SSSAPGASTQPPPHLPTKLVIRHGGAGGSPSVTWARASSSLSSSSSSSSAASSLDADEDG 1287
Query: 1506 PSPRRRSDRRRRYSS 1520
P P R + Y +
Sbjct: 1288 PMPSRNRPPIKTYEA 1302
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 105 bits (262), Expect = 4e-22
Identities = 97/388 (25%), Positives = 136/388 (35%), Gaps = 48/388 (12%)
Query: 771 SPQPPTGKWPSLPETPTGLADIPCLVIPPAPAKKTALQRSPETPLEICLVP---VGPSPA 827
+P PPT + P T T I PP +P P+ P PSP
Sbjct: 1421 TPSPPTTTTTTPPPTTTPSPPITTTTTPPPTT-------TPSPPISTTTTPPPTTTPSPP 1473
Query: 828 SPSPEPPVSKPVASSPTEQVPSQEMPLLARPSPPVQS-VSP----------AVPTPPSMS 876
+ +P PP + P + T P P PSPP + ++P P+PP+ +
Sbjct: 1474 TTTPSPPTTTPSPPTTTTTTP----PPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTT 1529
Query: 877 AALPFPAGGLGMPPSLP-PPPLQPPSLPLSMGPVLPDPFTHYAPLPSWPCYPHVSPSGYP 935
P P P + P PP +LP + P P T P + P P + P
Sbjct: 1530 TTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPP 1589
Query: 936 CL----PPPPTVPLVSGTPGAYAVPPTCSVPWAPPPAPVSPYSSTCTYGPLGWGPGPQHA 991
+ PPP T P S PP + P P P++P +ST T P P
Sbjct: 1590 TITTTTPPPTTTP--SPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPT---TTPSPP 1644
Query: 992 PFWSTVPPPPLPPASIGRAVPQPKMESRGTPAGPPENVLPLSMAPPLSLGLPGHGAPQTE 1051
P +T PPP P+ P P + + TP P++ P P T
Sbjct: 1645 PTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTP---------SPPTTT 1695
Query: 1052 PTKVEVKPVPASPHPKHKVSALVQSPQMKALACVSAEGVTVEEPASERLK--PETQETRP 1109
T P+SP + +P + T P + + P T + P
Sbjct: 1696 MTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSP 1755
Query: 1110 REKPPLPATKAVPT--PRQSTVPKLPAV 1135
PLP + PT P +T P P V
Sbjct: 1756 LTTTPLPPSITPPTFSPFSTTTPTTPCV 1783
Score = 97.4 bits (241), Expect = 1e-19
Identities = 88/333 (26%), Positives = 118/333 (35%), Gaps = 28/333 (8%)
Query: 814 PLEICLVPVGPSPASPSPEPPVSKPVASSPTEQVPSQEMPLLARPSPPVQSVSPAVPT-- 871
P++ C+ PSP + +P PP + PT PS P PP + SP + T
Sbjct: 1391 PMDKCITT--PSPPTTTPSPPPTSTTTLPPTT-TPSPPTTTTTTP-PPTTTPSPPITTTT 1446
Query: 872 --PPSMSAALPFPAGGLGMPPSLPPPPLQPPSLPLSMGPVLPDPFTHYAP---LPSWPCY 926
PP+ + + P P + P PP PS P + P P T P PS P
Sbjct: 1447 TPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTT-PSPPTTTTTTPPPTTTPSPPTT 1505
Query: 927 PHVSPSGYPCLPPPPTVPLVSGTPGAYAVPPTCSVPWAPPPAPVSPYSSTCTYGPLGWGP 986
++P PP T P S PP + P P P++P +ST T P
Sbjct: 1506 TPITPPASTTTLPPTTTP--SPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPT---T 1560
Query: 987 GPQHAPFWSTVPPPPLPPASIGRAVPQPKMESRGTP---AGPPENVLPLSMAPPLSLGLP 1043
P P +T PPP P+ P P + TP P + PP + P
Sbjct: 1561 TPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSP 1620
Query: 1044 GHGAPQTEPTKVEVKPVPASPHPKHKVSAL---VQSPQMKALACVSAEGVTVEEPASERL 1100
P T PT P +P P + +P S T P
Sbjct: 1621 PTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTP----- 1675
Query: 1101 KPETQETRPREKPPLPATKAVPTPRQSTVPKLP 1133
P T + P P P T + TP +T P P
Sbjct: 1676 PPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSP 1708
Score = 72.8 bits (177), Expect = 3e-12
Identities = 134/613 (21%), Positives = 184/613 (30%), Gaps = 91/613 (14%)
Query: 564 TIQTNPIPTHLSLVDSAQASPMPVDSVEADPTAVGPVLAGPVPVDPGLVDLASTSSELVE 623
T T P T S S +P P + T P P P +T
Sbjct: 1444 TTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPP----TTTTTTPPPTTT 1499
Query: 624 PLPAEPVLINPVLADSAAVDPAVVP----ISDNLPPVDAVPSGPAPVDLA---LVDPVPN 676
P P I P A + + P P + PP PS P + +P
Sbjct: 1500 PSPPTTTPITPP-ASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPP 1558
Query: 677 DLTPVDPVLVKSRPTDPRRGAVSSALGGSAPQLLVESESLDPPKTIIPEVKEVVDSLKIE 736
TP P + P + + S P + + PP T P
Sbjct: 1559 TTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTT----PPPTTTP------------ 1602
Query: 737 SGTSATTHEARPRPLSLSEYRRRRQQRQAETEERSPQPPTGKWPSLPETPTGLADIPCLV 796
+ TT P P + +P PPT P P PT +P
Sbjct: 1603 --SPPTTTTTTPPPTT------------------TPSPPTTT-PITP--PTSTTTLPPTT 1639
Query: 797 IPPAPAKKTALQRSPETPLEICLVPVGPSPASPSPEPPVSKPVASSPTEQVPSQEMPLLA 856
P P T TP P + + PP + P SSP PS +
Sbjct: 1640 TPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTP--SSPITTTPSPPTTTMT 1697
Query: 857 RPSPPVQSVSPAVPTPPSMSAALPFPAGGLGMPPSL--PPPPLQPPSLPLSMGPVLPDPF 914
PSP SP T S P P PP+ P P PS P + LP P
Sbjct: 1698 TPSPTTTPSSPITTTTTPSSTTTPSP------PPTTMTTPSPTTTPSPPTTTMTTLP-PT 1750
Query: 915 THYAPLPSWPCYPHVSPSGYPCLPPPPTVPLVSGTPGAYAVPPTCSVPWAPPPAP--VSP 972
T +PL + P P ++P P P + TP VP W P P
Sbjct: 1751 TTSSPLTTTPLPPSITP--------PTFSPFSTTTPTTPCVPLCNWTGWLDSGKPNFHKP 1802
Query: 973 YSSTCTYGPLGWGPGPQHAPFWSTVPPPPLPPASIGRAVPQP-------KMESRGTPAGP 1025
T G + GPG P +P +G+ V K E +
Sbjct: 1803 GGDTELIGDV-CGPGWAANISCRATMYPDVPIGQLGQTVVCDVSVGLICKNEDQ-----K 1856
Query: 1026 PENVLPLSMAPPLSLGLPGHGA---PQTEPTKVEVKPVPASPHPKHKVSALVQSPQMKAL 1082
P V+P++ + + P T T P P + P + + +P
Sbjct: 1857 PGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGT 1916
Query: 1083 ACVSAEGVTVEEPASERLKPETQETRPREKPPLPATKAVPTPRQSTVPKLPAVHPARLRK 1142
+ +T + P +T P P T PTP T + P P
Sbjct: 1917 QTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTP-TPTGTQTPTTTPI-TTT 1973
Query: 1143 LSFLPTPRTQGSE 1155
+ PTP G++
Sbjct: 1974 TTVTPTPTPTGTQ 1986
Score = 57.4 bits (137), Expect = 1e-07
Identities = 91/458 (19%), Positives = 128/458 (27%), Gaps = 55/458 (12%)
Query: 571 PTHLSLVDSAQASPMPVDSVEADPTAVG---PVLAGPVPVDPGLVDLAST---SSELVEP 624
PT + + +P P + PT P P G +T ++ V P
Sbjct: 3874 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3933
Query: 625 LPAEPVLINPV---LADSAAVDPAVVPISDNLPPVDAVPSG----PAPVDLALVDPVPND 677
P P + + V P P P + + P P P
Sbjct: 3934 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3993
Query: 678 LTPVDPVLVKSRPTDPRRGAVSSALGGSAPQLLVESESLDPPKTIIPEVKEVVDSLKIES 737
+T V PT + + + P T V +
Sbjct: 3994 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 4053
Query: 738 GTSA-------TTHEARPRPLSLSEYRRRRQQRQAETEERSPQPPTGKWPSLPETPTGLA 790
GT TT P P T PTG +TPT
Sbjct: 4054 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTP 4108
Query: 791 DIPCLVIPPAPAKKTALQRSPETPLEICLVPVGPSPASPSPEPPVSKPVASSPTEQVPSQ 850
+ P P T Q TP+ V P+P + P + P+ ++ T
Sbjct: 4109 ITTTTTVTPTPTP-TGTQTPTTTPITTTTT-VTPTPTPTGTQTPTTTPITTTTTVTPTPT 4166
Query: 851 EMPLLARPSPPVQSVSPAVPTPPSMSAALPFPAGGLGMP-----PSLPPPPLQPPSLPLS 905
+ P+ + + PTP P P S PPP P S
Sbjct: 4167 PTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRS 4226
Query: 906 MGPVLPDPFTHYAPLP-----------SWPCYPHVSPSGYPCLPPPPTVPLVSGTP---- 950
L + T + LP S P P + G+ PPP T GTP
Sbjct: 4227 TSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGT 4286
Query: 951 --GAYAVP------PTCSVPWAPPPAPVSPYSSTCTYG 980
G+ + P T + W P P P+S S T G
Sbjct: 4287 TTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTG 4324
Score = 54.7 bits (130), Expect = 7e-07
Identities = 113/614 (18%), Positives = 167/614 (27%), Gaps = 46/614 (7%)
Query: 571 PTHLSLVDSAQASPMPVDSVEADPTAVG---PVLAGPVPVDPGLVDLAST---SSELVEP 624
PT + + +P P + PT P P G +T ++ V P
Sbjct: 2034 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2093
Query: 625 LPAEPVLINPV---LADSAAVDPAVVPISDNLPPVDAVPSG----PAPVDLALVDPVPND 677
P P + + V P P P + + P P P
Sbjct: 2094 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2153
Query: 678 LTPVDPVLVKSRPTDPRRGAVSSALGGSAPQLLVESESLDPPKTIIPEVKEVVDSLKIES 737
+T V PT + + + P T V +
Sbjct: 2154 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2213
Query: 738 GTSA-------TTHEARPRPLSLSEYRRRRQQRQAETEERSPQPPTGKWPSLPETPTGLA 790
GT TT P P T PTG +TPT
Sbjct: 2214 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTP 2268
Query: 791 DIPCLVIPPAPAKKTALQRSPETPLEICLVPVGPSPASPSPEPPVSKPVASSPTEQVPSQ 850
+ P P T Q TP+ V P+P + P + P+ ++ T
Sbjct: 2269 ITTTTTVTPTPTP-TGTQTPTTTPITTTTT-VTPTPTPTGTQTPTTTPITTTTTVTPTPT 2326
Query: 851 EMPLLARPSPPVQSVSPAVPTPPSMSAALPFPAGGLGMPPSLPPPPLQPPSLPLSMGPVL 910
+ P+ + + PTP P + ++ P P + + P+
Sbjct: 2327 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPIT 2385
Query: 911 PDPFTHYAPLPSWPCYPHVSPSGYPCLPPPPTVPLVSGTPGAYAVPPTCSVPWAPPPAPV 970
P P+ P +P P P + TP + T +V P P P
Sbjct: 2386 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV--TPTPTPT 2443
Query: 971 SPYSSTCTYGPLGWGPGPQHAPFWSTVPPPPLPPASIGRAVPQPKMESRGTPAGPPENVL 1030
+ T T P P T P P + P P TP P
Sbjct: 2444 GTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2502
Query: 1031 PLSMAPPLSLGLPGHGAPQTEP--TKVEVKPVPA-------SPHPKHKVSALVQSPQMKA 1081
P G P T P T V P P + P + + +P
Sbjct: 2503 TTVTPTPTPTGTQ---TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2559
Query: 1082 LACVSAEGVTVEEPASERLKPETQETRPREKPPLPATKAVPTPRQSTVPKLPAVHPARLR 1141
+ +T + P +T P P T PTP T + P P
Sbjct: 2560 TQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTP-TPTGTQTPTTTPI-TT 2616
Query: 1142 KLSFLPTPRTQGSE 1155
+ PTP G++
Sbjct: 2617 TTTVTPTPTPTGTQ 2630
Score = 54.7 bits (130), Expect = 7e-07
Identities = 113/614 (18%), Positives = 167/614 (27%), Gaps = 46/614 (7%)
Query: 571 PTHLSLVDSAQASPMPVDSVEADPTAVG---PVLAGPVPVDPGLVDLAST---SSELVEP 624
PT + + +P P + PT P P G +T ++ V P
Sbjct: 2218 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2277
Query: 625 LPAEPVLINPV---LADSAAVDPAVVPISDNLPPVDAVPSG----PAPVDLALVDPVPND 677
P P + + V P P P + + P P P
Sbjct: 2278 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2337
Query: 678 LTPVDPVLVKSRPTDPRRGAVSSALGGSAPQLLVESESLDPPKTIIPEVKEVVDSLKIES 737
+T V PT + + + P T V +
Sbjct: 2338 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2397
Query: 738 GTSA-------TTHEARPRPLSLSEYRRRRQQRQAETEERSPQPPTGKWPSLPETPTGLA 790
GT TT P P T PTG +TPT
Sbjct: 2398 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTP 2452
Query: 791 DIPCLVIPPAPAKKTALQRSPETPLEICLVPVGPSPASPSPEPPVSKPVASSPTEQVPSQ 850
+ P P T Q TP+ V P+P + P + P+ ++ T
Sbjct: 2453 ITTTTTVTPTPTP-TGTQTPTTTPITTTTT-VTPTPTPTGTQTPTTTPITTTTTVTPTPT 2510
Query: 851 EMPLLARPSPPVQSVSPAVPTPPSMSAALPFPAGGLGMPPSLPPPPLQPPSLPLSMGPVL 910
+ P+ + + PTP P + ++ P P + + P+
Sbjct: 2511 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPIT 2569
Query: 911 PDPFTHYAPLPSWPCYPHVSPSGYPCLPPPPTVPLVSGTPGAYAVPPTCSVPWAPPPAPV 970
P P+ P +P P P + TP + T +V P P P
Sbjct: 2570 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV--TPTPTPT 2627
Query: 971 SPYSSTCTYGPLGWGPGPQHAPFWSTVPPPPLPPASIGRAVPQPKMESRGTPAGPPENVL 1030
+ T T P P T P P + P P TP P
Sbjct: 2628 GTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2686
Query: 1031 PLSMAPPLSLGLPGHGAPQTEP--TKVEVKPVPA-------SPHPKHKVSALVQSPQMKA 1081
P G P T P T V P P + P + + +P
Sbjct: 2687 TTVTPTPTPTGTQ---TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2743
Query: 1082 LACVSAEGVTVEEPASERLKPETQETRPREKPPLPATKAVPTPRQSTVPKLPAVHPARLR 1141
+ +T + P +T P P T PTP T + P P
Sbjct: 2744 TQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTP-TPTGTQTPTTTPI-TT 2800
Query: 1142 KLSFLPTPRTQGSE 1155
+ PTP G++
Sbjct: 2801 TTTVTPTPTPTGTQ 2814
Score = 54.7 bits (130), Expect = 7e-07
Identities = 113/614 (18%), Positives = 167/614 (27%), Gaps = 46/614 (7%)
Query: 571 PTHLSLVDSAQASPMPVDSVEADPTAVG---PVLAGPVPVDPGLVDLAST---SSELVEP 624
PT + + +P P + PT P P G +T ++ V P
Sbjct: 2402 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2461
Query: 625 LPAEPVLINPV---LADSAAVDPAVVPISDNLPPVDAVPSG----PAPVDLALVDPVPND 677
P P + + V P P P + + P P P
Sbjct: 2462 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2521
Query: 678 LTPVDPVLVKSRPTDPRRGAVSSALGGSAPQLLVESESLDPPKTIIPEVKEVVDSLKIES 737
+T V PT + + + P T V +
Sbjct: 2522 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2581
Query: 738 GTSA-------TTHEARPRPLSLSEYRRRRQQRQAETEERSPQPPTGKWPSLPETPTGLA 790
GT TT P P T PTG +TPT
Sbjct: 2582 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTP 2636
Query: 791 DIPCLVIPPAPAKKTALQRSPETPLEICLVPVGPSPASPSPEPPVSKPVASSPTEQVPSQ 850
+ P P T Q TP+ V P+P + P + P+ ++ T
Sbjct: 2637 ITTTTTVTPTPTP-TGTQTPTTTPITTTTT-VTPTPTPTGTQTPTTTPITTTTTVTPTPT 2694
Query: 851 EMPLLARPSPPVQSVSPAVPTPPSMSAALPFPAGGLGMPPSLPPPPLQPPSLPLSMGPVL 910
+ P+ + + PTP P + ++ P P + + P+
Sbjct: 2695 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPIT 2753
Query: 911 PDPFTHYAPLPSWPCYPHVSPSGYPCLPPPPTVPLVSGTPGAYAVPPTCSVPWAPPPAPV 970
P P+ P +P P P + TP + T +V P P P
Sbjct: 2754 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV--TPTPTPT 2811
Query: 971 SPYSSTCTYGPLGWGPGPQHAPFWSTVPPPPLPPASIGRAVPQPKMESRGTPAGPPENVL 1030
+ T T P P T P P + P P TP P
Sbjct: 2812 GTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2870
Query: 1031 PLSMAPPLSLGLPGHGAPQTEP--TKVEVKPVPA-------SPHPKHKVSALVQSPQMKA 1081
P G P T P T V P P + P + + +P
Sbjct: 2871 TTVTPTPTPTGTQ---TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2927
Query: 1082 LACVSAEGVTVEEPASERLKPETQETRPREKPPLPATKAVPTPRQSTVPKLPAVHPARLR 1141
+ +T + P +T P P T PTP T + P P
Sbjct: 2928 TQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTP-TPTGTQTPTTTPI-TT 2984
Query: 1142 KLSFLPTPRTQGSE 1155
+ PTP G++
Sbjct: 2985 TTTVTPTPTPTGTQ 2998
Score = 54.7 bits (130), Expect = 7e-07
Identities = 113/614 (18%), Positives = 167/614 (27%), Gaps = 46/614 (7%)
Query: 571 PTHLSLVDSAQASPMPVDSVEADPTAVG---PVLAGPVPVDPGLVDLAST---SSELVEP 624
PT + + +P P + PT P P G +T ++ V P
Sbjct: 2586 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2645
Query: 625 LPAEPVLINPV---LADSAAVDPAVVPISDNLPPVDAVPSG----PAPVDLALVDPVPND 677
P P + + V P P P + + P P P
Sbjct: 2646 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2705
Query: 678 LTPVDPVLVKSRPTDPRRGAVSSALGGSAPQLLVESESLDPPKTIIPEVKEVVDSLKIES 737
+T V PT + + + P T V +
Sbjct: 2706 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2765
Query: 738 GTSA-------TTHEARPRPLSLSEYRRRRQQRQAETEERSPQPPTGKWPSLPETPTGLA 790
GT TT P P T PTG +TPT
Sbjct: 2766 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTP 2820
Query: 791 DIPCLVIPPAPAKKTALQRSPETPLEICLVPVGPSPASPSPEPPVSKPVASSPTEQVPSQ 850
+ P P T Q TP+ V P+P + P + P+ ++ T
Sbjct: 2821 ITTTTTVTPTPTP-TGTQTPTTTPITTTTT-VTPTPTPTGTQTPTTTPITTTTTVTPTPT 2878
Query: 851 EMPLLARPSPPVQSVSPAVPTPPSMSAALPFPAGGLGMPPSLPPPPLQPPSLPLSMGPVL 910
+ P+ + + PTP P + ++ P P + + P+
Sbjct: 2879 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPIT 2937
Query: 911 PDPFTHYAPLPSWPCYPHVSPSGYPCLPPPPTVPLVSGTPGAYAVPPTCSVPWAPPPAPV 970
P P+ P +P P P + TP + T +V P P P
Sbjct: 2938 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV--TPTPTPT 2995
Query: 971 SPYSSTCTYGPLGWGPGPQHAPFWSTVPPPPLPPASIGRAVPQPKMESRGTPAGPPENVL 1030
+ T T P P T P P + P P TP P
Sbjct: 2996 GTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3054
Query: 1031 PLSMAPPLSLGLPGHGAPQTEP--TKVEVKPVPA-------SPHPKHKVSALVQSPQMKA 1081
P G P T P T V P P + P + + +P
Sbjct: 3055 TTVTPTPTPTGTQ---TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3111
Query: 1082 LACVSAEGVTVEEPASERLKPETQETRPREKPPLPATKAVPTPRQSTVPKLPAVHPARLR 1141
+ +T + P +T P P T PTP T + P P
Sbjct: 3112 TQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTP-TPTGTQTPTTTPI-TT 3168
Query: 1142 KLSFLPTPRTQGSE 1155
+ PTP G++
Sbjct: 3169 TTTVTPTPTPTGTQ 3182
Score = 54.7 bits (130), Expect = 7e-07
Identities = 113/614 (18%), Positives = 167/614 (27%), Gaps = 46/614 (7%)
Query: 571 PTHLSLVDSAQASPMPVDSVEADPTAVG---PVLAGPVPVDPGLVDLAST---SSELVEP 624
PT + + +P P + PT P P G +T ++ V P
Sbjct: 2770 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2829
Query: 625 LPAEPVLINPV---LADSAAVDPAVVPISDNLPPVDAVPSG----PAPVDLALVDPVPND 677
P P + + V P P P + + P P P
Sbjct: 2830 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2889
Query: 678 LTPVDPVLVKSRPTDPRRGAVSSALGGSAPQLLVESESLDPPKTIIPEVKEVVDSLKIES 737
+T V PT + + + P T V +
Sbjct: 2890 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2949
Query: 738 GTSA-------TTHEARPRPLSLSEYRRRRQQRQAETEERSPQPPTGKWPSLPETPTGLA 790
GT TT P P T PTG +TPT
Sbjct: 2950 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTP 3004
Query: 791 DIPCLVIPPAPAKKTALQRSPETPLEICLVPVGPSPASPSPEPPVSKPVASSPTEQVPSQ 850
+ P P T Q TP+ V P+P + P + P+ ++ T
Sbjct: 3005 ITTTTTVTPTPTP-TGTQTPTTTPITTTTT-VTPTPTPTGTQTPTTTPITTTTTVTPTPT 3062
Query: 851 EMPLLARPSPPVQSVSPAVPTPPSMSAALPFPAGGLGMPPSLPPPPLQPPSLPLSMGPVL 910
+ P+ + + PTP P + ++ P P + + P+
Sbjct: 3063 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPIT 3121
Query: 911 PDPFTHYAPLPSWPCYPHVSPSGYPCLPPPPTVPLVSGTPGAYAVPPTCSVPWAPPPAPV 970
P P+ P +P P P + TP + T +V P P P
Sbjct: 3122 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV--TPTPTPT 3179
Query: 971 SPYSSTCTYGPLGWGPGPQHAPFWSTVPPPPLPPASIGRAVPQPKMESRGTPAGPPENVL 1030
+ T T P P T P P + P P TP P
Sbjct: 3180 GTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3238
Query: 1031 PLSMAPPLSLGLPGHGAPQTEP--TKVEVKPVPA-------SPHPKHKVSALVQSPQMKA 1081
P G P T P T V P P + P + + +P
Sbjct: 3239 TTVTPTPTPTGTQ---TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3295
Query: 1082 LACVSAEGVTVEEPASERLKPETQETRPREKPPLPATKAVPTPRQSTVPKLPAVHPARLR 1141
+ +T + P +T P P T PTP T + P P
Sbjct: 3296 TQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTP-TPTGTQTPTTTPI-TT 3352
Query: 1142 KLSFLPTPRTQGSE 1155
+ PTP G++
Sbjct: 3353 TTTVTPTPTPTGTQ 3366
Score = 54.7 bits (130), Expect = 7e-07
Identities = 113/614 (18%), Positives = 167/614 (27%), Gaps = 46/614 (7%)
Query: 571 PTHLSLVDSAQASPMPVDSVEADPTAVG---PVLAGPVPVDPGLVDLAST---SSELVEP 624
PT + + +P P + PT P P G +T ++ V P
Sbjct: 2954 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3013
Query: 625 LPAEPVLINPV---LADSAAVDPAVVPISDNLPPVDAVPSG----PAPVDLALVDPVPND 677
P P + + V P P P + + P P P
Sbjct: 3014 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3073
Query: 678 LTPVDPVLVKSRPTDPRRGAVSSALGGSAPQLLVESESLDPPKTIIPEVKEVVDSLKIES 737
+T V PT + + + P T V +
Sbjct: 3074 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3133
Query: 738 GTSA-------TTHEARPRPLSLSEYRRRRQQRQAETEERSPQPPTGKWPSLPETPTGLA 790
GT TT P P T PTG +TPT
Sbjct: 3134 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTP 3188
Query: 791 DIPCLVIPPAPAKKTALQRSPETPLEICLVPVGPSPASPSPEPPVSKPVASSPTEQVPSQ 850
+ P P T Q TP+ V P+P + P + P+ ++ T
Sbjct: 3189 ITTTTTVTPTPTP-TGTQTPTTTPITTTTT-VTPTPTPTGTQTPTTTPITTTTTVTPTPT 3246
Query: 851 EMPLLARPSPPVQSVSPAVPTPPSMSAALPFPAGGLGMPPSLPPPPLQPPSLPLSMGPVL 910
+ P+ + + PTP P + ++ P P + + P+
Sbjct: 3247 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPIT 3305
Query: 911 PDPFTHYAPLPSWPCYPHVSPSGYPCLPPPPTVPLVSGTPGAYAVPPTCSVPWAPPPAPV 970
P P+ P +P P P + TP + T +V P P P
Sbjct: 3306 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV--TPTPTPT 3363
Query: 971 SPYSSTCTYGPLGWGPGPQHAPFWSTVPPPPLPPASIGRAVPQPKMESRGTPAGPPENVL 1030
+ T T P P T P P + P P TP P
Sbjct: 3364 GTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3422
Query: 1031 PLSMAPPLSLGLPGHGAPQTEP--TKVEVKPVPA-------SPHPKHKVSALVQSPQMKA 1081
P G P T P T V P P + P + + +P
Sbjct: 3423 TTVTPTPTPTGTQ---TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3479
Query: 1082 LACVSAEGVTVEEPASERLKPETQETRPREKPPLPATKAVPTPRQSTVPKLPAVHPARLR 1141
+ +T + P +T P P T PTP T + P P
Sbjct: 3480 TQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTP-TPTGTQTPTTTPI-TT 3536
Query: 1142 KLSFLPTPRTQGSE 1155
+ PTP G++
Sbjct: 3537 TTTVTPTPTPTGTQ 3550
Score = 54.7 bits (130), Expect = 7e-07
Identities = 113/614 (18%), Positives = 167/614 (27%), Gaps = 46/614 (7%)
Query: 571 PTHLSLVDSAQASPMPVDSVEADPTAVG---PVLAGPVPVDPGLVDLAST---SSELVEP 624
PT + + +P P + PT P P G +T ++ V P
Sbjct: 3138 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3197
Query: 625 LPAEPVLINPV---LADSAAVDPAVVPISDNLPPVDAVPSG----PAPVDLALVDPVPND 677
P P + + V P P P + + P P P
Sbjct: 3198 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3257
Query: 678 LTPVDPVLVKSRPTDPRRGAVSSALGGSAPQLLVESESLDPPKTIIPEVKEVVDSLKIES 737
+T V PT + + + P T V +
Sbjct: 3258 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3317
Query: 738 GTSA-------TTHEARPRPLSLSEYRRRRQQRQAETEERSPQPPTGKWPSLPETPTGLA 790
GT TT P P T PTG +TPT
Sbjct: 3318 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTP 3372
Query: 791 DIPCLVIPPAPAKKTALQRSPETPLEICLVPVGPSPASPSPEPPVSKPVASSPTEQVPSQ 850
+ P P T Q TP+ V P+P + P + P+ ++ T
Sbjct: 3373 ITTTTTVTPTPTP-TGTQTPTTTPITTTTT-VTPTPTPTGTQTPTTTPITTTTTVTPTPT 3430
Query: 851 EMPLLARPSPPVQSVSPAVPTPPSMSAALPFPAGGLGMPPSLPPPPLQPPSLPLSMGPVL 910
+ P+ + + PTP P + ++ P P + + P+
Sbjct: 3431 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPIT 3489
Query: 911 PDPFTHYAPLPSWPCYPHVSPSGYPCLPPPPTVPLVSGTPGAYAVPPTCSVPWAPPPAPV 970
P P+ P +P P P + TP + T +V P P P
Sbjct: 3490 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV--TPTPTPT 3547
Query: 971 SPYSSTCTYGPLGWGPGPQHAPFWSTVPPPPLPPASIGRAVPQPKMESRGTPAGPPENVL 1030
+ T T P P T P P + P P TP P
Sbjct: 3548 GTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3606
Query: 1031 PLSMAPPLSLGLPGHGAPQTEP--TKVEVKPVPA-------SPHPKHKVSALVQSPQMKA 1081
P G P T P T V P P + P + + +P
Sbjct: 3607 TTVTPTPTPTGTQ---TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3663
Query: 1082 LACVSAEGVTVEEPASERLKPETQETRPREKPPLPATKAVPTPRQSTVPKLPAVHPARLR 1141
+ +T + P +T P P T PTP T + P P
Sbjct: 3664 TQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTP-TPTGTQTPTTTPI-TT 3720
Query: 1142 KLSFLPTPRTQGSE 1155
+ PTP G++
Sbjct: 3721 TTTVTPTPTPTGTQ 3734
Score = 54.7 bits (130), Expect = 7e-07
Identities = 113/614 (18%), Positives = 167/614 (27%), Gaps = 46/614 (7%)
Query: 571 PTHLSLVDSAQASPMPVDSVEADPTAVG---PVLAGPVPVDPGLVDLAST---SSELVEP 624
PT + + +P P + PT P P G +T ++ V P
Sbjct: 3322 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3381
Query: 625 LPAEPVLINPV---LADSAAVDPAVVPISDNLPPVDAVPSG----PAPVDLALVDPVPND 677
P P + + V P P P + + P P P
Sbjct: 3382 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3441
Query: 678 LTPVDPVLVKSRPTDPRRGAVSSALGGSAPQLLVESESLDPPKTIIPEVKEVVDSLKIES 737
+T V PT + + + P T V +
Sbjct: 3442 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3501
Query: 738 GTSA-------TTHEARPRPLSLSEYRRRRQQRQAETEERSPQPPTGKWPSLPETPTGLA 790
GT TT P P T PTG +TPT
Sbjct: 3502 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTP 3556
Query: 791 DIPCLVIPPAPAKKTALQRSPETPLEICLVPVGPSPASPSPEPPVSKPVASSPTEQVPSQ 850
+ P P T Q TP+ V P+P + P + P+ ++ T
Sbjct: 3557 ITTTTTVTPTPTP-TGTQTPTTTPITTTTT-VTPTPTPTGTQTPTTTPITTTTTVTPTPT 3614
Query: 851 EMPLLARPSPPVQSVSPAVPTPPSMSAALPFPAGGLGMPPSLPPPPLQPPSLPLSMGPVL 910
+ P+ + + PTP P + ++ P P + + P+
Sbjct: 3615 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPIT 3673
Query: 911 PDPFTHYAPLPSWPCYPHVSPSGYPCLPPPPTVPLVSGTPGAYAVPPTCSVPWAPPPAPV 970
P P+ P +P P P + TP + T +V P P P
Sbjct: 3674 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV--TPTPTPT 3731
Query: 971 SPYSSTCTYGPLGWGPGPQHAPFWSTVPPPPLPPASIGRAVPQPKMESRGTPAGPPENVL 1030
+ T T P P T P P + P P TP P
Sbjct: 3732 GTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3790
Query: 1031 PLSMAPPLSLGLPGHGAPQTEP--TKVEVKPVPA-------SPHPKHKVSALVQSPQMKA 1081
P G P T P T V P P + P + + +P
Sbjct: 3791 TTVTPTPTPTGTQ---TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3847
Query: 1082 LACVSAEGVTVEEPASERLKPETQETRPREKPPLPATKAVPTPRQSTVPKLPAVHPARLR 1141
+ +T + P +T P P T PTP T + P P
Sbjct: 3848 TQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTP-TPTGTQTPTTTPI-TT 3904
Query: 1142 KLSFLPTPRTQGSE 1155
+ PTP G++
Sbjct: 3905 TTTVTPTPTPTGTQ 3918
Score = 54.3 bits (129), Expect = 1e-06
Identities = 60/241 (24%), Positives = 76/241 (31%), Gaps = 21/241 (8%)
Query: 925 CYPH----VSPSGYPCLPPPPTVPLVSGTPGAYAVPPTCSVPWAPPPAPV-SPYSSTCTY 979
C+P +PS P PP + P PPT + PPP SP +T T
Sbjct: 1389 CWPMDKCITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTT-TTPPPTTTPSPPITTTTT 1447
Query: 980 GPLGWGPGPQHAPFWSTVPPPPLPPASIGRAVPQPKMESRGTPAGPPENVLPLSMAPPLS 1039
P P P P +T PPP S P P T PP + PP +
Sbjct: 1448 PPPTTTPSP---PISTTTTPPPTTTPSPPTTTPSPPT----TTPSPPTTT--TTTPPPTT 1498
Query: 1040 LGLPGHGAPQTEPTKVEVKPVPASPHPKHKVS-----ALVQSPQMKALACVSAEGVTVEE 1094
P P T P P +P P + SP T+
Sbjct: 1499 TPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPP 1558
Query: 1095 PASERLKPETQETRPREKPPLPATKAVPTPRQ-STVPKLPAVHPARLRKLSFLPTPRTQG 1153
+ P T T P P P T P+P +T P P+ + P P T
Sbjct: 1559 TTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTP 1618
Query: 1154 S 1154
S
Sbjct: 1619 S 1619
Score = 53.9 bits (128), Expect = 1e-06
Identities = 92/503 (18%), Positives = 140/503 (27%), Gaps = 44/503 (8%)
Query: 571 PTHLSLVDSAQASPMPVDSVEADPTAVG---PVLAGPVPVDPGLVDLAST---SSELVEP 624
PT + + +P P + PT P P G +T ++ V P
Sbjct: 3759 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3818
Query: 625 LPAEPVLINPV---LADSAAVDPAVVPISDNLPPVDAVPSG----PAPVDLALVDPVPND 677
P P + + V P P P + + P P P
Sbjct: 3819 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3878
Query: 678 LTPVDPVLVKSRPTDPRRGAVSSALGGSAPQLLVESESLDPPKTIIPEVKEVVDSLKIES 737
+T V PT + + + P T V +
Sbjct: 3879 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3938
Query: 738 GTSA-------TTHEARPRPLSLSEYRRRRQQRQAETEERSPQPPTGKWPSLPETPTGLA 790
GT TT P P T PTG +TPT
Sbjct: 3939 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-----QTPTTTP 3993
Query: 791 DIPCLVIPPAPAKKTALQRSPETPLEICLVPVGPSPASPSPEPPVSKPVASSPTEQVPSQ 850
+ P P T Q TP+ V P+P + P + P+ ++ T
Sbjct: 3994 ITTTTTVTPTPTP-TGTQTPTTTPITTTTT-VTPTPTPTGTQTPTTTPITTTTTVTPTPT 4051
Query: 851 EMPLLARPSPPVQSVSPAVPTPPSMSAALPFPAGGLGMPPSLPPPPLQPPSLPLSMGPVL 910
+ P+ + + PTP P + ++ P P + + P+
Sbjct: 4052 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPIT 4110
Query: 911 PDPFTHYAPLPSWPCYPHVSPSGYPCLPPPPTVPLVSGTPGAYAVPPTCSVPWAPPPA-- 968
P P+ P +P P P + TP + T +V P P
Sbjct: 4111 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 4170
Query: 969 ---PVSPYSSTCTYGPLGWGPGPQHAP-----------FWSTVPPPPLPPASIGRAVPQP 1014
+P ++T T P G Q P ++ PPP R+ P
Sbjct: 4171 QTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSP 4230
Query: 1015 KMESRGTPAGPPENVLPLSMAPP 1037
ES + P + S APP
Sbjct: 4231 LTESTTLLSTLPPAIEMTSTAPP 4253
Score = 52.4 bits (124), Expect = 4e-06
Identities = 105/572 (18%), Positives = 157/572 (27%), Gaps = 40/572 (6%)
Query: 606 PVDPGLVDLASTSSELVEPLPA--EPVLINPVLADSAAVDPAVVPISDNLPPVDAVPSG- 662
P P + +T++ P P + P+ + V P P P + +
Sbjct: 1893 PTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITT-TTTVTPTPTPTGTQTPTTTPITTTT 1951
Query: 663 ---PAPVDLALVDPVPNDLTPVDPVLVKSRPTDPRRGAVSSALGGSAPQLLVESESLDPP 719
P P P +T V PT + + + P
Sbjct: 1952 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2011
Query: 720 KTIIPEVKEVVDSLKIESGTSA-------TTHEARPRPLSLSEYRRRRQQRQAETEERSP 772
T V +GT TT P P T
Sbjct: 2012 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2071
Query: 773 QPPTGKWPSLPETPTGLADIPCLVIPPAPAKKTALQRSPETPLEICLVPVGPSPASPSPE 832
PTG +TPT + P P T Q TP+ V P+P +
Sbjct: 2072 PTPTGT-----QTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTT-VTPTPTPTGTQ 2124
Query: 833 PPVSKPVASSPTEQVPSQEMPLLARPSPPVQSVSPAVPTPPSMSAALPFPAGGLGMPPSL 892
P + P+ ++ T + P+ + + PTP P + ++
Sbjct: 2125 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTV 2183
Query: 893 PPPPLQPPSLPLSMGPVLPDPFTHYAPLPSWPCYPHVSPSGYPCLPPPPTVPLVSGTPGA 952
P P + + P+ P P+ P +P P P + TP
Sbjct: 2184 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2243
Query: 953 YAVPPTCSVPWAPPPAPVSPYSSTCTYGPLGWGPGPQHAPFWSTVPPPPLPPASIGRAVP 1012
+ T +V P P P + T T P P T P P + P
Sbjct: 2244 TPITTTTTV--TPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTP 2300
Query: 1013 QPKMESRGTPAGPPENVLPLSMAPPLSLGLPGHGAPQTEP--TKVEVKPVPA-------S 1063
P TP P P G P T P T V P P +
Sbjct: 2301 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ---TPTTTPITTTTTVTPTPTPTGTQTPT 2357
Query: 1064 PHPKHKVSALVQSPQMKALACVSAEGVTVEEPASERLKPETQETRPREKPPLPATKAVPT 1123
P + + +P + +T + P +T P P T PT
Sbjct: 2358 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPT 2416
Query: 1124 PRQSTVPKLPAVHPARLRKLSFLPTPRTQGSE 1155
P T + P P + PTP G++
Sbjct: 2417 P-TPTGTQTPTTTPI-TTTTTVTPTPTPTGTQ 2446
Score = 47.8 bits (112), Expect = 9e-05
Identities = 83/407 (20%), Positives = 124/407 (30%), Gaps = 50/407 (12%)
Query: 767 TEERSPQPPTGKWPSLPETPTGLADIPCLVIPPAPAKKTALQRSPETPLEICLVPVGPSP 826
T +P PPT + P T T + P P T Q TP+ V P+P
Sbjct: 1888 TTTENPTPPT----TTPITTT-------TTVTPTPTP-TGTQTPTTTPITTTTT-VTPTP 1934
Query: 827 ASPSPEPPVSKPV----ASSPTEQVPSQEMPLLARPSPPVQSVSPAVPTPPSMSAALPFP 882
+ P + P+ +PT + P + P+ + + PTP P
Sbjct: 1935 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTPTGTQTP-T 1989
Query: 883 AGGLGMPPSLPPPPLQPPSLPLSMGPVLPDPFTHYAPLPSWPCYPHVSPSGYPCLPPPPT 942
+ ++ P P + + P+ P P+ P +P P
Sbjct: 1990 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2049
Query: 943 VPLVSGTPGAYAVPPTCSVPWAPPPA-----PVSPYSSTCTYGPLGWGPGPQHAPFWSTV 997
P + TP + T +V P P +P ++T T P P P T
Sbjct: 2050 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPT-----GTQ 2101
Query: 998 PPPPLPPASIGRAVPQPKMESRGTPAGPPENVLPLSMAPPLSLGLPGHGAPQTEP--TKV 1055
P P + P P TP P P G P T P T
Sbjct: 2102 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ---TPTTTPITTTT 2158
Query: 1056 EVKPVPA-------SPHPKHKVSALVQSPQMKALACVSAEGVTVEEPASERLKPETQETR 1108
V P P + P + + +P + +T + P +T
Sbjct: 2159 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT- 2217
Query: 1109 PREKPPLPATKAVPTPRQSTVPKLPAVHPARLRKLSFLPTPRTQGSE 1155
P P T PTP T + P P + PTP G++
Sbjct: 2218 PTTTPITTTTTVTPTP-TPTGTQTPTTTPI-TTTTTVTPTPTPTGTQ 2262
>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
1 [Homo sapiens]
Length = 1250
Score = 103 bits (257), Expect = 1e-21
Identities = 144/498 (28%), Positives = 187/498 (37%), Gaps = 127/498 (25%)
Query: 795 LVIPPAPAKK-----TALQRSPETPLEICLVPVGPSPASPSPEPPVSKPVASSPTE---- 845
LV P +P K TA Q SP P P P P P P PP P S+P+
Sbjct: 605 LVPPLSPQPKIVTPYTASQPSPPLPPP---PPPPPPPPPPPPPPPPPLPSQSAPSAGSAA 661
Query: 846 ------------QVPSQEMPLLARP-SPPV---QSVSPAVPTPPSMSAALPFPAGGLGMP 889
Q SQ L +P +PPV QSV P + PP+ G+ P
Sbjct: 662 PMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPN----------GVVPP 711
Query: 890 PSLPPPPLQPPSLPLSMGPVLPDPFTHYAPLPSWPCYP-------HVSPSGYPCLPPPPT 942
P PPPP P S +M + P P P S P P H++ P PPPP
Sbjct: 712 PPPPPPPPTPGS---AMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPP 768
Query: 943 VPLVSGTPGAYAVPPTCSVPWAPPPAPVSPYSSTCTYGPLGWGPGPQHAPFWSTVPPPPL 1002
+P P PP P PAP +ST T P+ P P PP+
Sbjct: 769 IP----APLPPQAPPK---PLVTIPAP----TSTKTVAPVVTQAAPP-------TPTPPV 810
Query: 1003 PPASIGRAVPQPKMESRGTPAGPPENVLPLSMAPPLSLGLPGHGAPQTEPTKVEVKPVP- 1061
PPA QP + P PP P+ + PP LP + +P + PVP
Sbjct: 811 PPAK-----KQPAFPASYIPPSPPTP--PVPVPPPT---LPKQQSFCAKPPPSPLSPVPS 860
Query: 1062 -----ASPHPKHKVSALVQSPQMKALACVSAEGVTVEEPASERLKPETQETR-----PRE 1111
AS P ++S +K + V + P + + KP+ Q + P
Sbjct: 861 VVKQIASQFPPPPTPPAMESQPLKPVPA----NVAPQSPPAVKAKPKWQPSSIPVPSPDF 916
Query: 1112 KPPLPATKAV-PTPRQSTVPKLPAVHPARLRKLSFLPTPRTQGSEDVVQAFISEIGIEAS 1170
PP P + V P P S VP P P PTP GS G + S
Sbjct: 917 PPPPPESSLVFPPPPPSPVPAPPPPPPPTAS-----PTPDKSGSP----------GKKTS 961
Query: 1171 DLSSLLEQFEKSEAKKECPPPAPADSLAVGNSGGVDIPQEKRP-LDRLQAPELANVAGLT 1229
SS KK PPP P + ++ +S G + P+ KRP +D L V+ T
Sbjct: 962 KTSS-------PGGKK--PPPTPQRNSSIKSSSGAEHPEPKRPSVDSL-------VSKFT 1005
Query: 1230 PPA---TPPHQLWKPLAA 1244
PPA +P + P AA
Sbjct: 1006 PPAESGSPSKETLPPPAA 1023
Score = 99.4 bits (246), Expect = 3e-20
Identities = 146/596 (24%), Positives = 203/596 (34%), Gaps = 108/596 (18%)
Query: 619 SELVEPLPAEPVLINPVLADSAAVDPAVVPISDNLPPVDAVPSGPAPVDLALVDPVPNDL 678
+ LV PL +P ++ P A + P + P PP P P P P+P+
Sbjct: 603 TSLVPPLSPQPKIVTPYTASQPS--PPLPPPPPPPPPPPPPPPPPPP-------PLPSQS 653
Query: 679 TP----VDPVLVKSRPTDPRRGAV--SSALGGSAPQLLVESES-----LDPPKTIIPEVK 727
P P+ VK + A S AL +++S+S L PP ++P
Sbjct: 654 APSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPP 713
Query: 728 ---------EVVDSLK-IESGTSATTHEARPRPLSLSEYRRRRQQRQAETEERSPQPPTG 777
+ LK S A P PL + Q Q T+ P PP
Sbjct: 714 PPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKI-------HQVQHITQVAPPTPP-- 764
Query: 778 KWPSLPETPTGLADIPCLVIPPAPAKKTALQRSPETPLEICLVPVGPSPASPSPEPPVSK 837
P P IP + P AP K +P + + V +P +P+P P +K
Sbjct: 765 -----PPPP-----IPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAK 814
Query: 838 PVASSPTEQVPSQEMPLLARPSPPVQSVSPAVP------TPPSMSAALPFPAGGLGMPPS 891
+ P +P P+PPV P +P P S P P+ +
Sbjct: 815 KQPAFPASYIPPSP------PTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQ 868
Query: 892 LPPPPLQPP--SLPLSMGP--VLPDPFTHYAPLPSWPCYPHVSPSGYPCLPPPPTVPLVS 947
PPPP P S PL P V P P W P P P PPPP +
Sbjct: 869 FPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQ--PSSIPVPSPDFPPPPPESSLV 926
Query: 948 GTPGAYAVPPTCSVPWAPPPAPVSPYSSTCTYGPLGWGPGPQHAPFWSTVPPPPLPPASI 1007
P PP VP PPP P + + G G +P PP P +SI
Sbjct: 927 FPP-----PPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSI 981
Query: 1008 ----GRAVPQPKMESRGTPAGPPENVLPLSMAPPLSLGLPGHGAPQTEPTKVEVKPVPAS 1063
G P+PK P + L PP G P+K + P A
Sbjct: 982 KSSSGAEHPEPKR--------PSVDSLVSKFTPPAESG---------SPSKETLPPPAAP 1024
Query: 1064 PHPKHKVSALVQSPQMKALACVSAEGVTVEEPASERLKPETQETRPREKPPLPATKAVPT 1123
P P + V P + CVSA+ + + + + PP P +P
Sbjct: 1025 PKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPL 1084
Query: 1124 P--------RQSTVPKLPAVHP-------ARLRKLSFLPTPRTQGSEDVVQAFISE 1164
P +T PK+ V+P ++K P+ S + QA ISE
Sbjct: 1085 PPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISE 1140
Score = 69.3 bits (168), Expect = 3e-11
Identities = 135/583 (23%), Positives = 175/583 (30%), Gaps = 183/583 (31%)
Query: 771 SPQPPTGKWPSLPETPTGLADIPCLVIPPAPAKKTALQRSPETPLEICLVPVGPSPASPS 830
S Q +G + P I V A + T L+ S + +E P S
Sbjct: 551 SNQSDSGVSDTQPAGHVRSQSIVSSVFSEAWKRGTQLEESSKARMESMNRPYTSLVPPLS 610
Query: 831 PEPPVSKPVASSPTEQVPSQEMPLLARPSPPVQSVSPAVPTPPSMSAALPFPAGGLGMPP 890
P+P + P +S +PSPP+ P P PP PP
Sbjct: 611 PQPKIVTPYTAS--------------QPSPPLPPPPPPPPPPPP--------------PP 642
Query: 891 SLPPPPLQPPSLPLSMGPVLPDPFTHYAPLPSWPCYPHVSPSGYPCLPPPPTVPLVSGTP 950
PPPPL S P S G P F Y+ + SG PP P V
Sbjct: 643 PPPPPPLPSQSAP-SAGSAAP-MFVKYSTITR--LQNASQHSGALFKPPTPPVMQSQSVK 698
Query: 951 GAYAVPPTCSVPWAPPPAPVSPYSSTCTYGPLGWGPGPQHAPFWSTVPPPPLPPASIGRA 1010
VPP VP PPP PPPP P +++ +
Sbjct: 699 PQILVPPNGVVPPPPPP------------------------------PPPPTPGSAMAQL 728
Query: 1011 VPQPKMESRGTPAGPPENVLPLSMAPPLSLGLPGHGAPQTEPTKVEVKPVPASPHPKHKV 1070
P P S + PP PPL + H PT P+PA P+
Sbjct: 729 KPAPCAPSLPQFSAPP---------PPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPP 779
Query: 1071 SALVQSPQMKALACVSAEGVTVEEPASERLKPETQETRPREKPPLPATKAVPTPRQSTVP 1130
LV P + V A VT P + P +++P PA+ P+P VP
Sbjct: 780 KPLVTIPAPTSTKTV-APVVTQAAPPT----PTPPVPPAKKQPAFPASYIPPSPPTPPVP 834
Query: 1131 KLPAVHPARLRKLSFLPTPRTQGSEDVVQAFISEIGIEASDLSSLLEQFEKSEAKKECPP 1190
P P ++ SF P S + S+++Q A + PP
Sbjct: 835 VPPPTLP---KQQSFCAKPPPS---------------PLSPVPSVVKQI----ASQFPPP 872
Query: 1191 PAPADSLAVGNSGGVDIPQEKRPLDRLQAPELANVAGLTPPATPPHQLWKPLAAVSLLAK 1250
P P E +PL P ANVA +PPA W+
Sbjct: 873 PTPP-------------AMESQPLK----PVPANVAPQSPPAVKAKPKWQ---------- 905
Query: 1251 AKSPKSTAQEGTLKPEGVTEAKHPAAVRLQEGVHGPSRVHVGSGDHDYCVRSRTPPKKMP 1310
PS + V S D PP
Sbjct: 906 -----------------------------------PSSIPVPSPDFP-------PPPPES 923
Query: 1311 ALVIPEVGSRWNVKRHQDITIKPVLSLGPAAPPPPCIAASREP 1353
+LV P P S PA PPPP AS P
Sbjct: 924 SLVFPP----------------PPPSPVPAPPPPPPPTASPTP 950
Score = 68.6 bits (166), Expect = 5e-11
Identities = 142/589 (24%), Positives = 191/589 (32%), Gaps = 110/589 (18%)
Query: 523 AWARAWAAALENSSPKNLERSAGQSSPAKEGPLDLYPKLADTIQTN----PIPTHLSLVD 578
AW R LE SS +E S + + PL PK+ + P+P
Sbjct: 580 AWKRG--TQLEESSKARME-SMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPP 636
Query: 579 SAQASPMPVDSVEADPTAVGPVLAGPVPVDPGLVDLASTSSE----LVEPLPAEPVLINP 634
P P +A A P+ V + +S+ L +P P PV+ +
Sbjct: 637 PPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKP-PTPPVMQSQ 695
Query: 635 VLADSAAVDP-AVVPISDNLPPVDAVPSG-----PAPVDLAL----VDPVPNDLTPVDPV 684
+ V P VVP PP S PAP +L P P + V +
Sbjct: 696 SVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHI 755
Query: 685 LVKSRPTDPRRGAVSSALGGSAP-QLLVESESLDPPKTIIPEVKEVVDSLKIESGTSATT 743
+ PT P + + L AP + LV + KT+ P V T
Sbjct: 756 TQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVV----------------T 799
Query: 744 HEARPRPLSLSEYRRRRQQRQAETEERSPQPPTGKWPSLPET------------PTGLAD 791
A P P ++Q P PPT P P T P+ L+
Sbjct: 800 QAAPPTPTP--PVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSP 857
Query: 792 IPCLVIP-----PAPAKKTALQRSPETPLEICLVPVGPSPASPSPEPPVSKPVASSPTEQ 846
+P +V P P A++ P P+ + P P P+ S SP
Sbjct: 858 VPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFP 917
Query: 847 VPSQEMPLLARPSPPVQSVSPAVPTPPSMSAALPFPAGGLGMPPSL---------PPPPL 897
P E L+ P PP +P P PP+ S P +G G S PP P
Sbjct: 918 PPPPESSLVFPPPPPSPVPAPPPPPPPTASPT-PDKSGSPGKKTSKTSSPGGKKPPPTPQ 976
Query: 898 QPPSLPLSMGPVLPDPFTHYAPLPSWPCYPHVSPSGYPCLPPPPTVPLVSGTPGAYAVPP 957
+ S+ S G P+P L T P SG+P +PP
Sbjct: 977 RNSSIKSSSGAEHPEP----------------KRPSVDSLVSKFTPPAESGSPSKETLPP 1020
Query: 958 TCSVPWAPPPAPVSPYSSTCTYGPLGWGPGPQHAPFWS-----TVPPPPLPPASIGRAVP 1012
P APP S G L G AP S +V P PP+
Sbjct: 1021 ----PAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPS------- 1069
Query: 1013 QPKMESRGTPAGPPENVLPLSMAPPLSLGLPGHGAPQTEPTKVEVKPVP 1061
P PPE LPL PP+ +P + T P V P P
Sbjct: 1070 -----DSDFPPPPPETELPL---PPIE--IPAVFSGNTSPKVAVVNPQP 1108
Score = 35.4 bits (80), Expect = 0.47
Identities = 65/306 (21%), Positives = 98/306 (32%), Gaps = 57/306 (18%)
Query: 1095 PASERLKPETQETRPREKPPLPATKAVPTPRQSTVPKLPAVHPARLRKLSFLPTPRTQGS 1154
P S + K T T + PPLP P P P P LP+ +
Sbjct: 608 PLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPP----------LPSQSAPSA 657
Query: 1155 EDVVQAFISEIGIEASDLSSLLEQFEKSEAKKECPPPAPADSLAVGNSGGVDIPQEKRPL 1214
F+ + S ++ L + S A + P P S +V PQ P
Sbjct: 658 GSAAPMFV-----KYSTITRLQNASQHSGALFKPPTPPVMQSQSVK-------PQILVPP 705
Query: 1215 DRLQAPELANVAGLTPPATPPHQLWKPLAAVSLLAKAKSPKSTAQEGTLKPEGVTEAKHP 1274
+ G+ PP PP P +A++ L A S Q P
Sbjct: 706 N-----------GVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPP--------- 745
Query: 1275 AAVRLQEGVHGPSRVHVGSGDHDYCVRSRTPPKKMPALVIPEVGSRWNVKRHQDI---TI 1331
P ++H + PP +PA + P+ + V T+
Sbjct: 746 -----------PLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTV 794
Query: 1332 KPVLS-LGPAAPPPPCIAASREPLDHRTSSEQADPSAPCLAPSSLLSPEASPCRNDMNTR 1390
PV++ P P PP A ++P + + P+ P P L + S C +
Sbjct: 795 APVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSP 854
Query: 1391 TPPEPS 1396
P PS
Sbjct: 855 LSPVPS 860
Score = 31.6 bits (70), Expect = 6.7
Identities = 23/88 (26%), Positives = 35/88 (39%), Gaps = 4/88 (4%)
Query: 175 PERDLITPVDPLGPSTGSSRGSGVEMSLPDPSWDFSPP----SFLETSSPKLPSWRPPRS 230
P + + V P P ++ S+P PS DF PP S + P P PP
Sbjct: 882 PLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPP 941
Query: 231 RPRWGQSPPPQQRSDGEEEEEVASFSGQ 258
P P + S G++ + +S G+
Sbjct: 942 PPPTASPTPDKSGSPGKKTSKTSSPGGK 969
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 99.8 bits (247), Expect = 2e-20
Identities = 156/557 (28%), Positives = 202/557 (36%), Gaps = 108/557 (19%)
Query: 653 LPPVDAVPSGPAPVDLALVDPVPNDLTPVDPVLVKSRPT---DPRRGAVSSALGGSAPQL 709
LPPVD +P P A P + + ++ R + D + S + P L
Sbjct: 757 LPPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPPSL 816
Query: 710 LVES----ESLDPPKTIIPEVKEVVDSLKIESGTSATTHEARPRPLSLSEYRRRRQQRQA 765
L + PP +I E + + + S + + P PL
Sbjct: 817 LWSAGQGQPGSQPPHSISTEFQTSHEH-SVSSAFKNSCNIPSPPPLPC------------ 863
Query: 766 ETEERSPQPPTGKWPSLPETPTGLA--DIPCLVIP-PAPAKKTALQRSPETPLEICLVPV 822
TE S P G P P G+ +P IP P P + T + P PL
Sbjct: 864 -TESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPL------- 915
Query: 823 GPSPASPSPEPPVSKPVASSPTEQVPSQEMPLLARPSPPVQSVSPAVPTPPSMSAA---L 879
P + P PP P +P +P P PP+ A+P PP + A L
Sbjct: 916 ---PGAGIPPPPPLPGAGILPLPPLPGAGIP----PPPPLPGA--AIPPPPPLPGAGIPL 966
Query: 880 PFPAGGLGMPPS--------LPPPPLQ----PPSLPLSMGPVLPDPFTHYAPLP--SWPC 925
P P G G+PP PPPPL PP PL + P P PLP P
Sbjct: 967 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP-----PLPGAGIPP 1021
Query: 926 YPHVSPSGYPCLPPPPT----VPLVSGTPGAYAVPPTCSVPWA--PPPAPVSPYSSTCTY 979
P + +G P PPPP +P PGA +PP +P A PPP P+ P +
Sbjct: 1022 PPPLPGAGIP--PPPPLPGAGIPPPPPLPGA-GIPPPPPLPGAGIPPPPPL-PGAGIPPP 1077
Query: 980 GPL-GWG-PGPQHAPFWSTVPPPPLPPASIGRAVPQPKMESRGTPAGPPENVLPLSMAPP 1037
PL G G P P P PPPPLP I P P + G P PP LP + PP
Sbjct: 1078 PPLPGAGIPPPPPLPGAGIPPPPPLPGVGI---PPPPPLPGAGIPPPPP---LPGAGIPP 1131
Query: 1038 LSLGLPGHGAPQTEP-TKVEVKPVP------ASPHPKHKVSALVQSPQMKALAC---VSA 1087
LPG G P P +V + P P P P + + P + +
Sbjct: 1132 -PPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPL 1190
Query: 1088 EGVTVEEPASERLKPETQETRPREKPPLPA-----TKAVPTPRQST----VPKLPAVHPA 1138
GV + P P PPLP A P P T P LP P
Sbjct: 1191 PGVGIPPP------PPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPP 1244
Query: 1139 RLRKL--SFLPTPRTQG 1153
L ++ S LPTP+ G
Sbjct: 1245 LLPQVGSSTLPTPQVCG 1261
Score = 88.2 bits (217), Expect = 6e-17
Identities = 143/594 (24%), Positives = 208/594 (35%), Gaps = 91/594 (15%)
Query: 537 PKNLERSAGQSSPAKEGPLDLYPKLADTIQTNPIPTHLSLVDSAQASPMPVDSVEADPTA 596
P +L SAGQ P + P + + + + + + + P+P +
Sbjct: 813 PPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPG 872
Query: 597 VGPVLAGPVPVDPGLVDLASTSSELVEPLPAEPVLINPVLADSAAVDPAVVPISDNLPPV 656
+G V P P+ PG+ S+ + +P P + + P + A +P LP
Sbjct: 873 LGMVPPPPPPL-PGMTVPTLPSTAIPQPPPLQGTEMLP--PPPPPLPGAGIPPPPPLPGA 929
Query: 657 DAVPSGPAP-VDLALVDPVPNDLTPVDPVLVKSRPT--DPRRGAVSSALGGSAPQLLVES 713
+P P P + P+P P P L + P GA G P +
Sbjct: 930 GILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGA------GIPPPPPLPG 983
Query: 714 ESLDPPKTIIPEVKEVVDSLKIESGTSATTHEARPRPLSLSEYRRRRQQRQAETEERSPQ 773
+ PP + G P PL + A P
Sbjct: 984 AGIPPPPPL--------------PGAGIPP----PPPLPGAGIPPPPPLPGAGIPPPPPL 1025
Query: 774 PPTGKWPSLPETPTGLADIPCL----VIPPAPAKKTALQRSPETPLEICLVPVGPSPASP 829
P G P P G+ P L + PP P + P P + P P P +
Sbjct: 1026 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP-GAGIPPPPPLPGAG 1084
Query: 830 SPEPPVSKPVASSPTEQVPSQEMPLLARPSPPVQSVSPAVPTPPSMSAA---LPFPAGGL 886
P PP P +P +P P PP+ +P PP + A P P G
Sbjct: 1085 IPPPPPLPGAGIPPPPPLPGVGIP----PPPPLPGAG--IPPPPPLPGAGIPPPPPLPGA 1138
Query: 887 GMPPSLPPPPLQ----PPSLPLSMGPVLPDPFTHYAPLPSWPCYPHVSPSGYPCLPPPPT 942
G+P PPPPL PP PL + P P A +P P P V +PPPP
Sbjct: 1139 GIP---PPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVG------IPPPPP 1189
Query: 943 VPLVSGTPGAYAVPPTCSVPWA--PPPAPVSPYSSTCTYGPLGWGPGPQHAPFWSTVPPP 1000
+P V +PP +P A PPP P+ + P P P + +PPP
Sbjct: 1190 LPGV-------GIPPPPPLPGAGIPPPPPLPGMG-------IPPAPAPPLPPPGTGIPPP 1235
Query: 1001 PLPPASIGRAVPQPKMESRGTPAGPPENVLPLSMAPPLSLGLPGHGAPQTEPT-KVEVKP 1059
PL P S +PQ + TP + + PPL GL G G Q + + K ++P
Sbjct: 1236 PLLPVSGPPLLPQVGSSTLPTPQ------VCGFLPPPLPSGLFGLGMNQDKGSRKQPIEP 1289
Query: 1060 V-PASP--------HPKH--KVSALVQSPQMKALACVSAEGVTVEEPASERLKP 1102
P P H K S + + + ++ C E + + ER KP
Sbjct: 1290 CRPMKPLYWTRIQLHSKRDSSTSLIWEKIEEPSIDCHEFEELFSKTAVKERKKP 1343
Score = 74.3 bits (181), Expect = 9e-13
Identities = 125/443 (28%), Positives = 154/443 (34%), Gaps = 102/443 (23%)
Query: 774 PPTGKWPSLPETPTGLADIP--------CLVIPPAPAKKTALQRSPETPLEICLVPVGPS 825
PP P P P G P L++ P ++ ++Q P + P P
Sbjct: 758 PPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSP---RRISVQLDSHQPTQSISQPPPPP 814
Query: 826 PA--SPSPEPPVSKPVASSPTEQVPSQEMPLLARPSPPVQSVSPA------VPTPPSM-- 875
S P S+P S TE S E SVS A +P+PP +
Sbjct: 815 SLLWSAGQGQPGSQPPHSISTEFQTSHE-----------HSVSSAFKNSCNIPSPPPLPC 863
Query: 876 ---SAALPFPAGGLGMPPSLPPPPL--------------QPPSLPLSMGPVLPD------ 912
S+++P GLGM P PPPPL QPP PL +LP
Sbjct: 864 TESSSSMP----GLGMVPP-PPPPLPGMTVPTLPSTAIPQPP--PLQGTEMLPPPPPPLP 916
Query: 913 ----------PFTHYAPLPSWP--CYPHVSPSGYPCLPPPPT-----VPLVSGTPGAYAV 955
P PLP P P P +PPPP +PL PGA +
Sbjct: 917 GAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGA-GI 975
Query: 956 PPTCSVPWA--PPPAPVSPYSSTCTYGPL-GWG-PGPQHAPFWSTVPPPPLPPASIGRAV 1011
PP +P A PPP P+ P + PL G G P P P PPPPLP A I
Sbjct: 976 PPPPPLPGAGIPPPPPL-PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI---P 1031
Query: 1012 PQPKMESRGTPAGPPENVLPLSMAPPLSLGLPGHGAPQTEPTKVEVKPVPASPHPKHKVS 1071
P P + G P PP LP + PP LPG G P P P P P P +
Sbjct: 1032 PPPPLPGAGIPPPPP---LPGAGIPP-PPPLPGAGIPPPPPLPGAGIP-PPPPLPGAGIP 1086
Query: 1072 ALVQSPQMKALACVSAEGVTVEEPASERLKPETQETRPREKPPLPATKAVPTPRQSTVPK 1131
P GV + P P PPLP P P +P
Sbjct: 1087 PPPPLPGAGIPPPPPLPGVGIPPP------PPLPGAGIPPPPPLPGAGIPPPP---PLPG 1137
Query: 1132 LPAVHPARLRKLSFLPTPRTQGS 1154
P L ++ P P G+
Sbjct: 1138 AGIPPPPPLPRVGIPPPPPLPGA 1160
Score = 34.7 bits (78), Expect = 0.79
Identities = 33/133 (24%), Positives = 51/133 (38%), Gaps = 17/133 (12%)
Query: 755 EYRRRRQQRQAETEERSPQPPTGKWPSLPETPTGLADIPCLVIPPAPAKKTALQRSPETP 814
+ ++++QQ+Q + E PPT P P + ++ P+ A SP+T
Sbjct: 216 QLQQQQQQQQLQGAEEPAAPPTAVSPQ----PGAFLGLDRFLLGPSGGAGEA-PGSPDTE 270
Query: 815 LEICLVPVGPSPASPSPEPPVSKPVASSPTEQVPSQEMPLLARPSPPVQSVSPAVPTPPS 874
+ + P + P P P +P+ PS P + PA PS
Sbjct: 271 QALSALSDLPESLAAEPREPQQPPSPGG---------LPVSEAPSLP--AAQPAAKDSPS 319
Query: 875 MSAALPFPAGGLG 887
S A PFP G G
Sbjct: 320 -STAFPFPEAGPG 331
Score = 32.7 bits (73), Expect = 3.0
Identities = 67/272 (24%), Positives = 90/272 (33%), Gaps = 58/272 (21%)
Query: 845 EQVPSQEMPLLARPSPPVQSVSPAVPTPPSMSAALPFPAGGLGMPPSLPPPPLQPPSLPL 904
+Q Q++ P+ P +VSP + L P+GG G P P L
Sbjct: 219 QQQQQQQLQGAEEPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSP-----DTEQAL 273
Query: 905 SMGPVLPDPFTHYAPLPSWPCYPHVSP-SGYPCLPPPPTVPLVSGTPGAYAVP-PTCSVP 962
S LP+ P P P P S P L P P +P + A P P
Sbjct: 274 SALSDLPESLAAEPREPQQPPSPGGLPVSEAPSL--PAAQPAAKDSPSSTAFPFPEAGPG 331
Query: 963 WAPPPAPVSPYSSTCTYG--------PLGWGPGPQHAPFWSTVPPPPLPPASIGRAVPQ- 1013
APV T G P G PG + AP +G PQ
Sbjct: 332 EEAAGAPVRGAGDTDEEGEEDAFEDAPRG-SPGEEWAP-------------EVGEDAPQR 377
Query: 1014 ----PKMESRGTPAGPPENVLPLSMAP--------PL-----------SLGLPGHGAPQT 1050
P+ E++G P P LP S AP PL L P H Q+
Sbjct: 378 LGEEPEEEAQG-PDAPAAASLPGSPAPSQRCFKPYPLITPCYIKTTTRQLSSPNHSPSQS 436
Query: 1051 --EPTKVEVKPVPASPHPKHKVSALVQSPQMK 1080
+ +++ +P P+ A V +P K
Sbjct: 437 PNQSPRIKRRPEPSLSRGSRTALASVAAPAKK 468
>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
Length = 2217
Score = 99.4 bits (246), Expect = 3e-20
Identities = 146/570 (25%), Positives = 198/570 (34%), Gaps = 128/570 (22%)
Query: 580 AQASPMPVDSVEADPTAVGPVLAGPVPVDPGLVDLASTSSEL---VEPLPAEPVLINPVL 636
A A+P P V + P + GPVL +P G + + L P PA P +
Sbjct: 641 ADAAPSPAQCVCSPPVSEGPVLPQSLP-SLGAYQQPTAAPGLPVGSVPAPACPPSLQQHF 699
Query: 637 ADSAAVDPAVVPISDNLPPVDAVPSGPAPVDLALVDPVPNDLTPVDPVLVKSRPTDPRRG 696
D A V+P PP +P+GP P P P P L + P
Sbjct: 700 PDPAMSFAPVLP-----PPSTPMPTGPG-------QPAPPGQQP--PPLAQPTP------ 739
Query: 697 AVSSALGGSAPQLLVESESLDPPKTIIPEVKEVVDSLKIESGTSATTHEARPRPLSLSEY 756
PQ+L P+ ++P +P P L Y
Sbjct: 740 ---------LPQVLA-------PQPVVP---------------------LQPVPPHLPPY 762
Query: 757 RRRRQQRQAETEERSPQPPTGKWPSLPETPTGLADIPCLVIPPAPAKKTALQRSPETPLE 816
Q A + + Q P L + P + IP V+PP TPL
Sbjct: 763 LAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIP--VVPPI------------TPLA 808
Query: 817 -ICLVPVGPSPASPSPEPPVSKPVASSPTEQVPSQEMPL-LARPSPPVQSVSPAVPTPPS 874
I +P + PPV P SP +PS PL A P+ P+Q+V +P PP
Sbjct: 809 GIDGLPPALPDLPTATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK--LPHPPG 866
Query: 875 MSAALPFPAGGLGMPPSLPPPPLQPPSL----------PLSMGPVLPDPFTHYAPLPSWP 924
A+P P ++P + PP + L PV P F AP P
Sbjct: 867 APLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQMAP-TDVP 925
Query: 925 CYPHVSPSGYPCLPPPPTVPLVSGTPGAYAVPPTCSVPWAPPPAPVSPYSSTCTYGPLGW 984
PH + PP P +P P +PP ++ PP PV P
Sbjct: 926 PSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQPTL----PPQPVLP------------ 969
Query: 985 GPGPQHAPFWSTVPPPPLPPASIGRAVPQPKMESRGTPAGP--PENVLPLSMAPPLSLGL 1042
P P P P P LPP + PQP + R P P PE P A P S L
Sbjct: 970 -PQPTRPPQPVLPPQPMLPPQPV--LPPQPALPVRPEPLQPHLPEQAAP--AATPGSQIL 1024
Query: 1043 PGHGAPQTEPTKVEVKPVPASPHPKHKVSALVQSPQMKALACVSAEGVTVEEPAS----- 1097
GH AP +V VP P A V SP + + +A + + P+S
Sbjct: 1025 LGHPAPYAVDVAAQVPTVPVPP-------AAVLSPPLPEVLLPAAPELLPQFPSSLATVS 1077
Query: 1098 ---ERLKPETQETRPREKPPLPATKAVPTP 1124
+ + +T P PPLP + +P
Sbjct: 1078 ASVQSVPTQTATLLPPANPPLPGGPGIASP 1107
Score = 91.3 bits (225), Expect = 7e-18
Identities = 138/548 (25%), Positives = 188/548 (34%), Gaps = 70/548 (12%)
Query: 780 PSLPETPTGLADIPCLVIPPAPAKKTALQRSPETPLEICLVPVGPSPASPSPEPPVSK-P 838
P+LP + T LA + Q S ++ + L PSPA PPVS+ P
Sbjct: 601 PTLPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGP 660
Query: 839 VASSPTEQVPSQEMPLLARPSPPVQSVSPAVPTPPSMSAALPFPAGGLG---MPPSLP-- 893
V + + + P A P PV SV PA PPS+ P PA PPS P
Sbjct: 661 VLPQSLPSLGAYQQP-TAAPGLPVGSV-PAPACPPSLQQHFPDPAMSFAPVLPPPSTPMP 718
Query: 894 -------PPPLQPPSLPLSMGPVLPDPFTHYAPLPSWPCYPHVSP-------SGYPCLPP 939
PP QPP PL+ LP +P P PH+ P G P
Sbjct: 719 TGPGQPAPPGQQPP--PLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLK 776
Query: 940 PPTVPLVSGTPGAYAVPPTCSVPWAPPPAPVS---------PYSSTCTYGPLGWGPGPQH 990
P +P P A P +P PP P++ P T T P+ P PQ+
Sbjct: 777 PLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPV---PPPQY 833
Query: 991 APFWSTVP--PPPLPPASIGRAVPQPKMESRGTPAGP------------PENVLPLSMAP 1036
+P PLPPAS A+P ++ P P P + L++AP
Sbjct: 834 FSPAVILPSLAAPLPPAS--PALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAP 891
Query: 1037 PLSLGLPGH-------GAPQTEPTKVEVKPVPASPHPKHKVSALVQSPQMKALACVSAEG 1089
P L H G P ++ P P P H V + +P AL
Sbjct: 892 PGVAALSIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLP 951
Query: 1090 VTVEEPASERLKPETQETRPREKPPLPATKAVP-TPRQSTVPKLPAVHPARLRKLS-FLP 1147
P L P+ +PP P P P Q +P PA+ P R L LP
Sbjct: 952 PQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPAL-PVRPEPLQPHLP 1010
Query: 1148 TPRTQGSEDVVQAFISEIGIEASDLSSLLEQFEKSEAKKECPPPAPADSLAVGNSGGVDI 1207
+ Q + A D+++ + A PP P L
Sbjct: 1011 EQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVPPA-AVLSPPLPEVLLPAAPELLPQF 1069
Query: 1208 PQEKRPLDRLQAPELANVAGLTPPATPP----HQLWKPLAAVSLLAKAKSPKSTAQEGTL 1263
P + A L PPA PP + P V L + + +Q+
Sbjct: 1070 PSSLATVSASVQSVPTQTATLLPPANPPLPGGPGIASPCPTVQLTVEPVQEEQASQD--- 1126
Query: 1264 KPEGVTEA 1271
KP G+ ++
Sbjct: 1127 KPPGLPQS 1134
Score = 72.4 bits (176), Expect = 3e-12
Identities = 109/410 (26%), Positives = 139/410 (33%), Gaps = 91/410 (22%)
Query: 809 RSPETPLEICLV-------PVGPSPASPSPE--------PPVSKPVASSPT--------- 844
R P PL++ + P P P P + P + +AS T
Sbjct: 565 RGPPVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLPPTLPTSATSLASDSTFDSGQGSTV 624
Query: 845 --EQVPSQEMPLL-----ARPSPPVQSVSPAVPTPPSMSAALPF------PAGGLGMPPS 891
+ SQ+ +L A PSP SP V P + +LP P G+P
Sbjct: 625 YSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVG 684
Query: 892 LPPPPLQPPSLPLSMGPVLPDPFTHYAPLPSWPCYPHVSPSGYPCLPPPPTVPLVSGTPG 951
P P PPSL PDP +AP+ P P + G P P PL TP
Sbjct: 685 SVPAPACPPSLQQHF----PDPAMSFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPL 740
Query: 952 AYAVPPTCSVPWAPPP-------APVSPYSSTCTYGPLGWGPGP-----QHAPFWSTVP- 998
+ P VP P P AP S + PL P Q P +P
Sbjct: 741 PQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPV 800
Query: 999 -PPPLPPASIGRAVPQ-PKMESRGTPAGPPEN------VLPLSMA--PPLSLGLP----- 1043
PP P A I P P + + P PP +LP A PP S LP
Sbjct: 801 VPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVK 860
Query: 1044 ---GHGAPQTEPTKVEVKPVPASPHPKHKVSAL-VQSPQMKALACVSAEGVTVEEPASER 1099
GAP P + V PA+ + L V P + AL+ SA +P
Sbjct: 861 LPHPPGAPLAMPCRTIVPNAPAT------IPLLAVAPPGVAALSIHSAVAQLPGQPVYPA 914
Query: 1100 LKPETQET-----------RPREKPPLPATKAVPT-PRQSTVPKLPAVHP 1137
P+ T R PP PA PT P Q +P P + P
Sbjct: 915 AFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPP 964
Score = 62.4 bits (150), Expect = 4e-09
Identities = 176/786 (22%), Positives = 251/786 (31%), Gaps = 182/786 (23%)
Query: 817 ICLVPVGPSPASPSPEPPVSKPVASSPTEQVPSQEMPLLARPSPPVQSVSPAVPTPPSMS 876
IC V P+P +P PP+ P++S P E ++ S P + + P ++
Sbjct: 1315 ICPVAEHPAPEAPESSPPL--PLSSLPPEA---------SQDSAPYKDQLSSKEQPSFLA 1363
Query: 877 AALPFPAGGLGMPPSLPPPPLQPPSLPLSMGP---------VLPDPFTHYAPLPSWPCYP 927
+ G PP PP PL P S P++ P +P+P + A P P
Sbjct: 1364 SQQLLSQAGPSNPPGAPPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTP 1423
Query: 928 H--------VSPSGYPCLPPPPTVPLVSGTPGAYAVPPTCSVPWA-------PPPAP-VS 971
P P PLV G P S A PPPAP S
Sbjct: 1424 QGLTSELETSQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPS 1483
Query: 972 PYSSTCTYGPLGWGPGP---QHAPF-----------WSTVPPPPLPPASIGRAVPQPKME 1017
P+S T P P Q AP S +P PPL P PQP
Sbjct: 1484 PHSGT---------PQPALGQPAPLLPAAVGAVSLATSQLPSPPLGPT----VPPQPPSA 1530
Query: 1018 SRGTPAGPPENV----------------------LPLSMAPPLSLGLP---GHGAPQTEP 1052
GPP V +P S A S G P G EP
Sbjct: 1531 LESDGEGPPPRVGFVDSTIKSLDEKLRTLLYQEHVPTSSA---SAGTPVEVGDRDFTLEP 1587
Query: 1053 -------TKVEVKPVPASPHPKHKVSALVQSPQ--MKALACVSAEGVTVEEPASERLKPE 1103
++V + P PK VS VQ PQ ++ G +E+ S +
Sbjct: 1588 LRGDQPRSEVCGGDLALPPVPKEAVSGRVQLPQPLVEKSELAPTRGAVMEQGTSSSM--- 1644
Query: 1104 TQETRPREKPPLPATKAVPTPRQSTVPKLPAVHPARLRKLSFLPTPRTQGSEDVVQAFIS 1163
T E+ PR VP +P PA +R PT R G
Sbjct: 1645 TAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPAFVRPARVEPTDRDGG---------- 1694
Query: 1164 EIGIEASDLSSLLEQFEKSEAKKECPPPAPADSLAVGNSGGVDIPQEKRPLDRLQAPELA 1223
EA + P P+D +G GG + P+
Sbjct: 1695 -------------------EAGESSAEPPPSD---MGTVGG-----------QASHPQTL 1721
Query: 1224 NVAGLTPPATPPHQLWKPLAAVSLLAKAKSPKSTAQEGTLKPEGVTEAKHPAAVRLQEGV 1283
L P P Q + +++ + S ST E TL P V L E
Sbjct: 1722 GARALGSPRKRPEQ--QDVSSPAKTVGRFSVVSTQDEWTLASPHSLRYSAPPDVYLDEAP 1779
Query: 1284 HGP------------SRVHVGSGD------HDYCVRSRTPPKKMPALVIPEVGSRWNVKR 1325
P S + VG G+ D R+R P +K +L + + VK+
Sbjct: 1780 SSPDVKLAVRRAQTASSIEVGVGEPVSSDSGDEGPRARPPVQKQASLPVSGSVAGDFVKK 1839
Query: 1326 HQDITIKP--VLSLGPAAP-----PPPCIAASREPLDHRTSSEQADPSAPCLAPSSLLSP 1378
+P SLGP P P I+ + H SS + + L + +
Sbjct: 1840 ATAFLQRPSRAGSLGPETPSRVGMKVPTISVTS---FHSQSSYISSDNDSELEDADIKKE 1896
Query: 1379 EASPCRNDMNTRTPPEPSAKQRSMRCYRKACRSASPSSQGWQ-----GRRGRNSRS-VSS 1432
S + + + KQ YR+ + P+ + GRR + S+S + +
Sbjct: 1897 LQSLREKHLKEISELQSQQKQEIEALYRRLGKPLPPNVGFFHTAPPTGRRRKTSKSKLKA 1956
Query: 1433 GSNRTSEASSSSSSSSSSSRSRSRSLSPPHKRWRRSSCSSSGRSRRCSSSSSSSSSSSSS 1492
G +SS+ S PP K ++S + S S + + S
Sbjct: 1957 GKLLNPLVRQLKVVASSTGHLADSSRGPPAKDPAQASVGLTADSTGLSGKAVQTQQPCSV 2016
Query: 1493 SSSSSS 1498
+S SS
Sbjct: 2017 RASLSS 2022
Score = 61.6 bits (148), Expect = 6e-09
Identities = 112/435 (25%), Positives = 158/435 (36%), Gaps = 77/435 (17%)
Query: 545 GQSSPAKEGPLDLYPKLADTIQTNPIPTHLSLVDSAQASPMPVDSVEADPTAVGPVLAGP 604
GQ +P + P P LA Q P+P L+ P PV ++ P + P LA
Sbjct: 722 GQPAPPGQQP----PPLA---QPTPLPQVLA--------PQPVVPLQPVPPHLPPYLAPA 766
Query: 605 VPVD-PGLVDLASTSSELVEPLPAEPVLINPVLADSAAVDPAVVPIS--DNLPPVDAVPS 661
V P + ++PL P + P+ V P + P++ D LPP A+P
Sbjct: 767 SQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPI-----PVVPPITPLAGIDGLPP--ALPD 819
Query: 662 GPAPVDLALVDPVPNDLTPVDPVLVKSRPTDPRRGAVSSALGGSAPQLLVESESLDPP-- 719
P A V PVP V++ S +++ L ++P L +++ L P
Sbjct: 820 LPT----ATVPPVPPPQYFSPAVILPS---------LAAPLPPASPALPLQAVKLPHPPG 866
Query: 720 -------KTIIPEVKEVVDSLKI-ESGTSA-TTHEA---------------RPRPLSLSE 755
+TI+P + L + G +A + H A + P +
Sbjct: 867 APLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQMAPTDVPP 926
Query: 756 YRRRRQQRQAETEERSPQPPTGKWPSLPETPTGLADIPCLVIPPAPAK--KTALQRSPET 813
Q T + PP P P P P V+PP P + + L P
Sbjct: 927 SPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPML 986
Query: 814 PLEICLVPVGPSPASPSPEPPVSKPVASSPTEQVPSQEMPLLARPSPPVQSVS---PAVP 870
P + L P P P P P P ++P SQ LL P+P V+ P VP
Sbjct: 987 PPQPVLPPQPALPVRPEPLQP-HLPEQAAPAATPGSQ--ILLGHPAPYAVDVAAQVPTVP 1043
Query: 871 TPPSMSAALPFPAGGLGMPPSLPPPPLQPPSLPLSMGPVLPDPFTHYAPLPSWPCYPHVS 930
PP+ + P P L P L P P SL V P LP P P +
Sbjct: 1044 VPPAAVLSPPLPEVLLPAAPELLPQ--FPSSLATVSASVQSVPTQTATLLP--PANPPL- 1098
Query: 931 PSGYPCLPPPPTVPL 945
P G P PTV L
Sbjct: 1099 PGGPGIASPCPTVQL 1113
Score = 48.1 bits (113), Expect = 7e-05
Identities = 104/477 (21%), Positives = 149/477 (31%), Gaps = 39/477 (8%)
Query: 660 PSGPAPVDLALVDPVPNDLTPVDPVLVKSRPTDPRRGAVSSALGGSAPQLLVESESLDPP 719
P G P LA P L S +P G S A G PQ L P
Sbjct: 1376 PPGAPPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQP 1435
Query: 720 KTIIPEVKEVVDSLKIESGTSATTHEARPRPLSLSEYRRRRQQRQAETEERSPQPPTGKW 779
E V L + G + T P P + S + + R P PP
Sbjct: 1436 LAETHEAPLAVQPLVV--GLAPCT----PAPEAAST--------RDASAPREPLPPPAPE 1481
Query: 780 PSLPE-TPTGLADIPCLVIPPAP-AKKTALQRSPETPLEICLVPVGPSPASPSPE-PPVS 836
PS TP P ++P A A A + P PL + P PS E PP
Sbjct: 1482 PSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPPPR 1541
Query: 837 KPVASSPTEQVPSQEMPLLARPSPPVQSVSPAVPTPPSMSAALPFPAGG-------LGMP 889
S + + + LL + P S S P P G G
Sbjct: 1542 VGFVDSTIKSLDEKLRTLLYQEHVPTSSASAGTPVEVGDRDFTLEPLRGDQPRSEVCGGD 1601
Query: 890 PSLPPPPLQPPSLPLSMGPVLPDPFTHYAPL-PSWPCYPHVSPSGYPCLPPPPTVPLVSG 948
+LPP P + S + LP P + L P+ S P L
Sbjct: 1602 LALPPVPKEAVSGRVQ----LPQPLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGYD 1657
Query: 949 TPGAYAVPPTCSVPWAPPPAPVSPYSSTCTYGPLGWGPGPQHAPFWSTVPPPPLPPASIG 1008
G + VP P P + G + S+ PPP ++G
Sbjct: 1658 RDGRQVASDSHVVPSVPQDVPAFVRPARVEPTDRDGGEAGE-----SSAEPPPSDMGTVG 1712
Query: 1009 RAVPQPKM---ESRGTPAGPPENVLPLSMAPPLSLGLPGHGAPQTEPTKVEVKPVPASPH 1065
P+ + G+P PE S P ++G + Q E T + S
Sbjct: 1713 GQASHPQTLGARALGSPRKRPEQQDVSS--PAKTVGRFSVVSTQDEWTLASPHSLRYSAP 1770
Query: 1066 PKHKVSALVQSPQMKALACVSAEGVTVEEPASERLKPETQETRPREKPPLPATKAVP 1122
P + SP +K + ++E E + ++ + PR +PP+ ++P
Sbjct: 1771 PDVYLDEAPSSPDVKLAVRRAQTASSIEVGVGEPVSSDSGDEGPRARPPVQKQASLP 1827
Score = 37.7 bits (86), Expect = 0.094
Identities = 58/253 (22%), Positives = 87/253 (34%), Gaps = 30/253 (11%)
Query: 646 VVPISDNLPPVDAVPSGPAPVDLALVDP-VPNDLTPV-DPVLVKSRPTDPRRGAVSSALG 703
+ P++++ P P P+ L+ + P D P D + K +P+ + S G
Sbjct: 1315 ICPVAEH--PAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAG 1372
Query: 704 GSAPQLLVESESLDPPKTIIPEVKEVVDSLKIESGTSATTHEARPRPLSLSEYRRRRQQR 763
S P PP + P V +L + AT+ P + S+ +
Sbjct: 1373 PSNPPGA-------PPAPLAPSSPPVT-ALPQDGAAPATSTMPEPASGTASQAGGPGTPQ 1424
Query: 764 QAETEERSPQPPTGKWPSLPETPTGLADIPCLVIPPAPAKKTALQRSPETPLEICLVPVG 823
+E + QP E P + + + P PA + A R P E
Sbjct: 1425 GLTSELETSQPLA----ETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPRE------- 1473
Query: 824 PSPASPSPEPPVSKPVASSPTEQ-VPSQEMPLLARPSPPVQSVSPAVPTPPSMSAALPFP 882
P P PP +P S T Q Q PLL V + +P+PP P P
Sbjct: 1474 -----PLP-PPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQP 1527
Query: 883 AGGLGMPPSLPPP 895
L PPP
Sbjct: 1528 PSALESDGEGPPP 1540
Score = 31.2 bits (69), Expect = 8.8
Identities = 45/159 (28%), Positives = 62/159 (38%), Gaps = 26/159 (16%)
Query: 554 PLDLYPKLADTIQTNPIPTHLSLVDSAQASPMPVDSVEADPTAVGPVLAGPVPVDPGLVD 613
P L P L + Q P T S + +P VD PT VPV P V
Sbjct: 1002 PEPLQPHLPE--QAAPAATPGSQILLGHPAPYAVDVAAQVPT---------VPVPPAAV- 1049
Query: 614 LASTSSELVEPLPAEPVLI----NPVLADSAAVDPAVVPISDNLPPVD-AVPSGPAPVDL 668
L+ E++ LPA P L+ + + SA+V + LPP + +P GP
Sbjct: 1050 LSPPLPEVL--LPAAPELLPQFPSSLATVSASVQSVPTQTATLLPPANPPLPGGP----- 1102
Query: 669 ALVDPVPNDLTPVDPVLVKSRPTDPRRGAVSS--ALGGS 705
+ P P V+PV + D G S + GGS
Sbjct: 1103 GIASPCPTVQLTVEPVQEEQASQDKPPGLPQSCESYGGS 1141
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 97.4 bits (241), Expect = 1e-19
Identities = 125/445 (28%), Positives = 164/445 (36%), Gaps = 76/445 (17%)
Query: 653 LPPVDAVPSGPAPVDLALVDPVPNDLTPVDPVLVKSRPTDP--RRGAVSSALGGSAPQLL 710
+PP P P P L P P PV R DP R ++ G+ + +
Sbjct: 3 VPPPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRKV 62
Query: 711 VESESLDPPKTIIPEVKEVVDSLKIESGTSATTHEARPRP----LSLSEYRRRRQQRQAE 766
+ P+ E E G SA T A P L + R Q +
Sbjct: 63 TQINDRSAPQI------ESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRD 116
Query: 767 TEE-RSPQPPTGKWPSLPETPTGLADIPCLVIPPAPAK-------KTALQRSPETPLEIC 818
++ Q P + PS P P P +IPPA + A + +P P
Sbjct: 117 VAGGKTGQGPGSRAPS-PRLPNKTISGP--LIPPASPRLGNTSEAHGAARTAPPRPN--- 170
Query: 819 LVPVGPSPASPSPEPPVSKPVASSPTEQVPSQEMP-LLARPSPPVQSVSPAVPTPPSMSA 877
VP P P P P PP+ P+ SS + P P L + + PV V+P VP P
Sbjct: 171 -VPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPV--VAPPVPCAP---- 223
Query: 878 ALPFPAGGLGMPPSLPPPPLQPPSLPLSMGPVLPDPFTHYAPLPSWPCYPHVSPSGYPCL 937
PP PPPP PP LP + VL D P ++P P +
Sbjct: 224 -----------PPPPPPPPPTPPPLPPAS--VLSDKAVK----------PQLAPLHLPPI 260
Query: 938 PPPPTVPLVSGTPGAYAVPPT----CSVPWAPPPAPVSPYSSTCTYGPLGWGPGPQHAPF 993
PPP + G PG A P + P APPP P+ PY+S L P P
Sbjct: 261 PPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPP-PLPPYASCSPRASLPAPPLP--GVN 317
Query: 994 WSTVPPPPLPPASIGRAVPQPKMESRGTPAGPPENVLPLSMAPPLS---LGLPGHGAPQT 1050
S+ PPPLPP S P K ++ PA P APP S L HG P
Sbjct: 318 SSSETPPPLPPKSPSFQAPPQKAGAQALPAPP---------APPGSQPFLQKKRHGRPGA 368
Query: 1051 EPTKVEVKPVPASPHPKHKVSALVQ 1075
K+ P P + P ++S+ Q
Sbjct: 369 GGGKLNPPPAPPARSPTTELSSKSQ 393
Score = 45.8 bits (107), Expect = 3e-04
Identities = 103/438 (23%), Positives = 144/438 (32%), Gaps = 71/438 (16%)
Query: 869 VPTPPSMSAALPFPAGGLGMPPSLPPPPLQPPSLPLSMGPVLPDPFTHYAPLPS------ 922
+P PP LP P LG PP PPPP PP + DP A L
Sbjct: 1 MPVPPPPPPPLPPPPPPLGAPP--PPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTR 58
Query: 923 WPCYPHVSPSGYPCLPPPPTVPLVSG----TPGAYAVPPTCSVPWAPPPAPVSPYSS-TC 977
++ P + G T GA + PPT +A + P
Sbjct: 59 LRKVTQINDRSAPQIESSKGTNKEGGGSANTRGA-STPPTLGDLFAGGFPVLRPAGQRDV 117
Query: 978 TYGPLGWGPG---PQHAPFWSTVPPPPLPPAS--IGR----------AVPQPKMESRGTP 1022
G G GPG P T+ P +PPAS +G A P+P + + P
Sbjct: 118 AGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPP 177
Query: 1023 AGPPENVLPLSMAPPLSLGLPGHGAPQTEPTKVEVKPVPASPHPKHKVSALVQSPQMKAL 1082
PP P + PPL P + P K P+ + P P K + V +P +
Sbjct: 178 TPPPP---PPPLPPPL---------PSSSPIKT---PLVSPPGPLTKGNLPVVAP---PV 219
Query: 1083 ACVSAEGVTVEEPASERLKPETQETRPREKPPLPATKAVPTPRQSTVPKLPAVHPARLRK 1142
C P L P + + KP L P P P LP + P
Sbjct: 220 PCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIP-----PPLPLLPPCGYPG 274
Query: 1143 LSFLPTPRTQGSED------VVQAFISEIGIEASDLSSLLEQFEKSEAKKECPPPAPADS 1196
L P Q +++ + + S + L SE PP +P+
Sbjct: 275 LKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQ 334
Query: 1197 LAVGNSGGVDIPQEKRP-------LDRLQAPELANVAGLTPPATPPHQLWKPLAAVSLLA 1249
+G +P P + A L PP PP + P +S
Sbjct: 335 APPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPAR--SPTTELS--- 389
Query: 1250 KAKSPKSTAQEGTLKPEG 1267
+KS ++TA T +P G
Sbjct: 390 -SKSQQATAWTPTQQPGG 406
Score = 32.7 bits (73), Expect = 3.0
Identities = 42/173 (24%), Positives = 62/173 (35%), Gaps = 32/173 (18%)
Query: 1304 TPPKKMPALVIPEVGSRWNVKRHQDITIKPVLS---LGPAAPP----PPC--IAASREPL 1354
TPP PA V+ D +KP L+ L P PP PPC EP
Sbjct: 233 TPPPLPPASVL------------SDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPA 280
Query: 1355 DHRTSSEQADPSAPCLAPSSLLSPEAS------PCRNDMNTRTPPEPSAKQRSMRCYRKA 1408
+++ P L P + SP AS P N + PP P +KA
Sbjct: 281 SPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKA 340
Query: 1409 CRSASPSSQGWQG-----RRGRNSRSVSSGSNRTSEASSSSSSSSSSSRSRSR 1456
A P+ G ++ R+ R + G + + S ++ S+S+
Sbjct: 341 GAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSPTTELSSKSQ 393
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens]
Length = 816
Score = 96.7 bits (239), Expect = 2e-19
Identities = 155/556 (27%), Positives = 200/556 (35%), Gaps = 95/556 (17%)
Query: 749 RPLSLSEYRRRRQQRQAETEERSPQPPTGKWPSLPETPTGLADI-PCLVIPPAPAKKTAL 807
R LS S R + +P+ P PS P+ P GL + P V PP AL
Sbjct: 231 RSLSSSATPLSSPARSGPSARGTPRAPAH--PSQPK-PKGLQALRPPQVTPPRKDAAPAL 287
Query: 808 QRSPETPLEICLVPVGPSP-ASPSPEPPVSKPVASSPTEQVPSQEMPLLARPSPPVQSVS 866
+PL PSP A PSP P S SP PSQ L SP +Q+
Sbjct: 288 GPLSSSPLAT------PSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLG--SPTLQATH 339
Query: 867 PAVPTPPSMSAALPFPAGGLGMPPSLPPPPLQPPSLPLSMGPVLPDPFTHYAPLPSWPCY 926
+P+PP A P P PP+L PPLQ P PS P
Sbjct: 340 SFLPSPPLSPLATPPPQA----PPALALPPLQAP--------------------PSPPAS 375
Query: 927 PHVSPSGYPCLPPPPTVPLVSGTPGAYAVPPTCSV--PWAPPPAP-VSPYSSTCTYGPLG 983
P +SP P P P V ++ PP+ V P++PP +P VSP ++
Sbjct: 376 PPLSPLATPS-PQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATP------- 427
Query: 984 WGPGPQHAPFWSTVPP---PPLPPASIGRAVPQPKMESRGTPAGPPENVLPLSMAPPLSL 1040
P AP PP PP PPAS P M TP PP+ PL+ APPL L
Sbjct: 428 ----PSQAPPSLAAPPLQVPPSPPAS-------PPMSPSATP--PPQAPPPLA-APPLQL 473
Query: 1041 GLPGHGAPQTEPT-KVEVKPVPASPHPKHKVSALVQSPQMKALACVSAEGVTV------E 1093
P AP T ++ P P + P + S M LA + V +
Sbjct: 474 AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQ 533
Query: 1094 EPASERLKPETQETRPREKPPLPATKAVPTPRQSTVPKLPAVHPARLRK-LSFLPTPRTQ 1152
P S P Q R +PP P + + T+ P P R S L P
Sbjct: 534 VPPSPPASPTLQAPR---RPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLA 590
Query: 1153 GSEDVVQAFISEI-GIEASDLSSLLEQFEKSEAKKECPPPA----PADSLAVGNSGGVDI 1207
G + E+ G ++ C P A PA LA + G +
Sbjct: 591 GHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPL 650
Query: 1208 PQEKR----------PLDRLQAPELANVA--GLTPPATPPHQLWKPLAAVSLLAKAKSPK 1255
P + + PE A A L P +P K A A ++SPK
Sbjct: 651 PWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPK 710
Query: 1256 STAQEGTLKPEGVTEA 1271
A+ G L P G +A
Sbjct: 711 Q-ARLGEL-PLGALQA 724
Score = 93.6 bits (231), Expect = 1e-18
Identities = 153/589 (25%), Positives = 215/589 (36%), Gaps = 55/589 (9%)
Query: 447 ANAAPGSQRARKG-RKKKSKEQPAACVEGYARRLRSSSRGQSTVGTEVTSQVDNLQKQPQ 505
A AP G R+ S P ARR R++ +++ + P+
Sbjct: 138 ATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPR 197
Query: 506 EELQKESGPLQGKGKPRAWARAWAAA-LENSSPKNLERSAGQ-SSPAKEGPLDLYPKLAD 563
+ + S + P A R A L+ + ++L SA SSPA+ GP A
Sbjct: 198 KSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAP 257
Query: 564 TIQTNPIPTHLSLVDSAQASPMPVDSVEADPTAVGPVLAGPVPVDPGLVDLASTSSELVE 623
+ P P L + Q +P D+ A+GP+ + P+ + ++ ++
Sbjct: 258 AHPSQPKPKGLQALRPPQVTPPRKDAA----PALGPLSSSPLATPSPSAPPSPSAPPSLQ 313
Query: 624 PLPAEPVLINPVLADSAAVDPAVVPISDNL--PPVD--AVPSGPAPVDLAL----VDPVP 675
LP+ P P A ++ P + L PP+ A P AP LAL P P
Sbjct: 314 TLPSPPA-TPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP 372
Query: 676 NDLTPVDPVLVKSRPTDPRRGAVSSALGGSAPQLLVESESLDPPKTIIPEVKEVVDSLKI 735
P+ P+ S P P AV L+++ PP + S +
Sbjct: 373 PASPPLSPLATPS-PQAPNALAVH----------LLQAPFSPPPSPPVQAPFSPPASPPV 421
Query: 736 ESGTSATTHEARPRPLSLSEYRRRRQQRQAETEERSPQPPTGKWPSLPETPTGLADIPCL 795
SAT P L+ + + S PP P L P LA P
Sbjct: 422 --SPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQ 479
Query: 796 VIPPAPAKKTALQRSPETPLEICLVPVGPSPASPSPEPPVSKPVASSPTEQVPSQEMPLL 855
PPA A LQ P P G +P SPS P+S P+A+ P + P PLL
Sbjct: 480 A-PPALA-TPPLQALPSPPASF----PGQAPFSPSASLPMS-PLATPPPQAPPVLAAPLL 532
Query: 856 -ARPSPPVQSV--SPAVPTPPSMSAALPFPAGGLGMPPSLPPPPLQPPSLPLSMGPVLPD 912
PSPP +P P P ++ P L + P PPPP + PS LS GP L
Sbjct: 533 QVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLS-GPDLAG 591
Query: 913 PFTHYAPLPSWPCYPHVSPSGYPCLPPPPTVPLVSGTPGAY----AVP------PTCSVP 962
+ P P G PPP L + P A+ A P P +P
Sbjct: 592 HSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLP 651
Query: 963 WAPPPAPVSPYSSTCTYGPLGWGPGPQHA-PFWSTVPPPPLPPASIGRA 1010
W P P S CT + GP+ A P + P P P S G+A
Sbjct: 652 WPPATGPGSA-DGLCT---IYETEGPESATPAPGALDPGPSPGTSGGKA 696
Score = 84.7 bits (208), Expect = 7e-16
Identities = 94/335 (28%), Positives = 124/335 (37%), Gaps = 55/335 (16%)
Query: 741 ATTHEARPRPLSLSEYRRR-----RQQRQAETEERSPQPPTGKWPSLPETPTGLADIPCL 795
A H ++P+P L R R+ S P PS P +P+ + L
Sbjct: 256 APAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTL 315
Query: 796 VIPPA--PAKKTALQRSPETPLEICLVPVGP-----------------SPASPSPEPPVS 836
PPA P++ T SP +P P P P PP S
Sbjct: 316 PSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPAS 375
Query: 837 KPVA--SSPTEQVPSQ------EMPLLARPSPPVQS-VSPAVPTPPSMSAALPFPAGGLG 887
P++ ++P+ Q P+ + P PSPPVQ+ SP P S SA
Sbjct: 376 PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSAT--------- 426
Query: 888 MPPSLPPPPLQPPSLPLSMGPVLPDPFTHYA-PLPSWPCYPHVSPSGYPCLPPPPTVPLV 946
PPS PP L P L + P P + A P P P P ++ PPP P
Sbjct: 427 -PPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP--PPLAAPPLQLAKPPPQAPPA 483
Query: 947 SGTPGAYAVP-PTCSVPWAPPPAPVSPYSSTCTYGPLGWGPGPQHAPFWST--VPPPPLP 1003
TP A+P P S P P +P S++ PL P PQ P + + PP P
Sbjct: 484 LATPPLQALPSPPASFPGQAPFSP----SASLPMSPLA-TPPPQAPPVLAAPLLQVPPSP 538
Query: 1004 PASIGRAVP-QPKMESRGTPAGPPENVLPLSMAPP 1037
PAS P +P T P L L+ PP
Sbjct: 539 PASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPP 573
Score = 49.3 bits (116), Expect = 3e-05
Identities = 154/726 (21%), Positives = 225/726 (30%), Gaps = 114/726 (15%)
Query: 802 AKKTALQRSPETPLEICLVPVGPSPASPSPEPPVSKPVASSPTEQVPSQEMPLLARPSPP 861
AK A R+P L P P SP P PPV+ PL R
Sbjct: 8 AKAGAAARTPAARAPGLLTP--RPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGI 65
Query: 862 VQSVSP--AVPTPPSMSAALPFPAGGLGMPPSLPPPPLQPPSLPLSMGPVLPDPFTHYAP 919
+ P A P+ ++ P G PP+ P S + G P P
Sbjct: 66 GGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGL 125
Query: 920 LPSWPCYPHVSPSGYPCLPPPPTVPLVSGTPGAYAVPPTCSVPWAPPPAPVSPYSSTCTY 979
+S P S + P P PA + T
Sbjct: 126 --------RISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTE 177
Query: 980 GPLGWGPGPQHAPFWSTVPPPPLPPASIGRAVPQPKMESRGTPAGPPENVLPLSMAPPLS 1039
L P+ AP PP P S+ A E +PA + P S
Sbjct: 178 VGL-----PRPAPSARPRPPTEGPRKSVSSASEHSTTEP--SPAARRRPSAGGGLQRPAS 230
Query: 1040 LGLPGHGAPQTEPTKV--EVKPVPASP-HPKHKVSALVQSPQMKALACVSAEGVTV-EEP 1095
L P + P + + P +P HP P+ K L + VT +
Sbjct: 231 RSLSSSATPLSSPARSGPSARGTPRAPAHPSQ--------PKPKGLQALRPPQVTPPRKD 282
Query: 1096 ASERLKPETQETRPREKPPLPATKAVPTPRQSTVPKLPAVHPARLRKLSFLPTPRTQGSE 1155
A+ L P + P P + + P P T+P PA P++ + L +P Q +
Sbjct: 283 AAPALGPLSSSPLATPSPSAPPSPSAP-PSLQTLPSPPATPPSQAT--TSLGSPTLQATH 339
Query: 1156 DVVQAFISEIGIEASDLSSLLEQFEKSEAKKECPPPAPADSLAVGNSGGVDIPQEKRPLD 1215
+ + LS L PPP +LA+ P PL
Sbjct: 340 SF---------LPSPPLSPLAT-----------PPPQAPPALALPPLQAPPSPPASPPLS 379
Query: 1216 RL-----QAPELANV----AGLTPPATPPHQLWKPLAAVSLLAKAKSPKSTAQEGTLKPE 1266
L QAP V A +PP +PP Q A ++ + +P S A P
Sbjct: 380 PLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPP 439
Query: 1267 GVTEAKHPAAVRLQEGVHGPSRVHVGSGDHDYCVRSRTPPKKMPALVIPEVGSRWNVKRH 1326
PA+ + PS + PP+ P L P +
Sbjct: 440 LQVPPSPPASPPMS-----PS--------------ATPPPQAPPPLAAPPLQ-------- 472
Query: 1327 QDITIKPVLSLGPAAPPPPCIAASREPLDHRTSSEQADPSAPCLAPSSLLSPEASPCRND 1386
KP PA PP A P + + ++ ++P + P+A P
Sbjct: 473 ---LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA 529
Query: 1387 MNTRTPPEPSAKQRSMRCYRKACRSASPSSQGWQGRRGRNSRSVSSGSNRTSEASSSSSS 1446
+ PP P ASP+ Q RR +S S + +
Sbjct: 530 PLLQVPPSP---------------PASPTLQA--PRRPPTPGPDTSVSGPRLTLALAPGP 572
Query: 1447 SSSSSRSRSRSLSPPHKRWRRSSCSSSGRSRRCSSSSSSSSSSSS----SSSSSSSSRSR 1502
SRS S +LS P SS +S+ R S +++S + ++ +
Sbjct: 573 PPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAW 632
Query: 1503 SRSPSP 1508
SR P+P
Sbjct: 633 SRGPAP 638
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 96.7 bits (239), Expect = 2e-19
Identities = 170/675 (25%), Positives = 239/675 (35%), Gaps = 109/675 (16%)
Query: 801 PAKKTALQRSP--ETPLEI---CLVPVGPSPASPSPE-----PPVSKPVASSPTEQVPSQ 850
P K +Q P E PL L P SP SP PE PP S P E++P+
Sbjct: 418 PLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPAS 477
Query: 851 EMP---LLARP------SPPVQSVSPAVPTPPSMSAALPFPAGGLGMP-----------P 890
+P L+RP SPP + SP P PP S P L P P
Sbjct: 478 PLPEALHLSRPLEESPLSPPPEE-SPLSP-PPESSPFSPLEESPLSPPEESPPSPALETP 535
Query: 891 SLPPPPLQPPSLPLSMGPVLPDPFTHYAPLPSWPCYPHVS-----PSGYPCLPPPPTVPL 945
PPP P S P P+ P P LP+ P P S P P PPP P+
Sbjct: 536 LSPPPEASPLSPPFEESPLSPPP----EELPTSP-PPEASRLSPPPEESPMSPPPEESPM 590
Query: 946 VSGTPGAYAVPPTCSVPWAPPP--APVSPYSSTCTYGPLGWGPGPQHAPFWSTVPP---P 1000
+ PP P +PPP +P+SP P P+ +P + PP P
Sbjct: 591 SPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRL-----SPPPEDSPM--SPPPEESP 643
Query: 1001 PLPPASIGRAVPQPKME-----SRGTPAGPPENVLPLSMAPPLSLGLPGHGAPQTEPTKV 1055
PP + R P P + +P PP P S P S P P+ PT
Sbjct: 644 MSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSP---PPEDSPTSP 700
Query: 1056 EVKPVPASPHPKHKVSA--LVQSPQM----KALACVSAEGVTVE----------EPASER 1099
+ PASP P+ + + L +SP + + C +EG + P
Sbjct: 701 PPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPH 760
Query: 1100 LKPETQETRPREKPPLPATKAVP-TPRQSTVPKLPAVHPARLRKLSFLPTPRTQGSEDVV 1158
L P+ +E +P P AVP P S + P + P + +L P V
Sbjct: 761 LSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSP-QPEELHLSPQTEEPHLSPVP 819
Query: 1159 QAFISEIGIEASDLSSLLEQ------FEKSEAKKEC--PPPAPADSLAVGNSGGVDIPQE 1210
+ E S LS E+ E+S E PP +P G P+E
Sbjct: 820 EEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEE 879
Query: 1211 KRPLDRLQAPELANVAG---LTPPATPPHQLWKPLAAVSLLAKAKSPKSTAQEGTLKPEG 1267
P L+ + G L+ P PP PL + P S + E +L P+
Sbjct: 880 LPLFPPPGEPSLSPLLGEPALSEPGEPP---LSPL-------PEELPLSPSGEPSLSPQL 929
Query: 1268 V-TEAKHPAAVRLQEGVHGPSRVHVGSGDHDYCVRSRTPPKKMPALVIPE--VGSRWNVK 1324
+ + P + P+ +G ++ + + + P+ A I E +
Sbjct: 930 MPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEAN 989
Query: 1325 RHQDITIKP-VLSLGPAAPPPPCIAASREPLDHRTSSEQADPSAPCLAPSSLLSPEASPC 1383
+ P +L P +P P EPL + S P +P S SP A P
Sbjct: 990 CTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALP- 1048
Query: 1384 RNDMNTRTPPEPSAK 1398
++ +P P K
Sbjct: 1049 ---LSVPSPLSPIGK 1060
Score = 94.0 bits (232), Expect = 1e-18
Identities = 212/856 (24%), Positives = 285/856 (33%), Gaps = 185/856 (21%)
Query: 510 KESGPLQGKGKPRAWARAWAAALENSSPKNLERSAGQSSPAKEGPLDLYPKLADTIQTNP 569
KE GPLQ + KP A LE L P +E PL P+ + T +P
Sbjct: 407 KEPGPLQCEAKPLGKA---GVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPT---SP 460
Query: 570 IPTHLSLVDSAQASPMPVDSVEADPTAVGPVLAGPVPVDPGLVDLASTSSELVEPLPAEP 629
P ++++ SP P + + A P L+ P+ P L+ E P E
Sbjct: 461 PP------EASRLSPPP-EELPASPLPEALHLSRPLEESP----LSPPPEESPLSPPPES 509
Query: 630 VLINPVLADSAAVDPAVVPISDNL-----PPVDAVPSGPAPVDLALVDPVPNDLTPVDPV 684
+P L +S P P S L PP +A P P P + + + P P +L P P
Sbjct: 510 SPFSP-LEESPLSPPEESPPSPALETPLSPPPEASPLSP-PFEESPLSPPPEEL-PTSPP 566
Query: 685 LVKSRPTDPRRGAVSSALGGSAPQLLVESESLDPPKTIIPEVKEVVDSLKIESGTSATTH 744
SR + P E + PP PE ES S
Sbjct: 567 PEASRLSPPP-----------------EESPMSPP----PE----------ESPMSPPPE 595
Query: 745 EARPRPLSLSEYRRRRQQRQAETEERSPQPPTGKWPSLPETPTGLADIPCLVIPPAPAKK 804
+R P EE PP + P P P P +P +
Sbjct: 596 ASRLFP---------------PFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPE 640
Query: 805 TALQRSPETPLEICLVPVGPSPASPSPEPPVSKPVASSPTEQVPSQEMPLLARPSPPVQS 864
+ P + +PV + P E P+S P SPT P +R SPP +
Sbjct: 641 ESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPE-----ASRLSPPPED 695
Query: 865 VSPAVPTPPSMSAALPFPAGGLGMPP----SLPPPPLQPPSLPLSMGPVL-PDP------ 913
SP P PP S A P P L P L P P +P P S GP L P P
Sbjct: 696 -SPTSP-PPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLS 753
Query: 914 -------------FTHYAPLPSWPCY------PHVSPSG-------------------YP 935
H +P P PC PH+SP P
Sbjct: 754 PRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEP 813
Query: 936 CLPPPPTVPLVSGTPGAYAVPPTCSVPWAPPPAPVSPYSSTCTYGPL-----------GW 984
L P P P +S P + P P P S S PL G
Sbjct: 814 HLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQ 873
Query: 985 GPGPQHAPFWSTVPPPPLPPASIGRAVPQPKMESRG-TPAGPPENVLPLSMA--PPLSLG 1041
P P+ P + PPP P S+ + +P + G P P LPLS + P LS
Sbjct: 874 CPAPEELPLF---PPPGEP--SLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQ 928
Query: 1042 L--PGHGAPQTEPTKVEVKPVPASP--HPKHKVSALVQSPQMKALACVSAEGVTVEEPAS 1097
L P P P P SP ++ A S LA E T P
Sbjct: 929 LMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILE--TPISPPP 986
Query: 1098 ERLKPETQETRPREKPPLPATKAVPTPRQSTVPKLPAVHPARLRKLSFLPTPRTQGSEDV 1157
E + + P PP P + P P P P L +P +Q S
Sbjct: 987 EANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPA 1046
Query: 1158 ----VQAFISEIG--IEASDLSSLLEQFEKSEAKKECPP------------------PAP 1193
V + +S IG + SD + L E + ++ ECP PAP
Sbjct: 1047 LPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAP 1106
Query: 1194 ADSLAVGNSGGVDIPQEKRPLDRLQAPELANVAGLTPPATPPHQLWKP-------LAAVS 1246
+ + A+ + G + ++ PLD + AP G TP + P LA V+
Sbjct: 1107 SPAPALDDFSG--LGEDTAPLDGIDAPGSQPEPGQTPGSLASELKGSPVLLDPEELAPVT 1164
Query: 1247 LLAKAKSPKSTAQEGT 1262
+ K TA +G+
Sbjct: 1165 PMEVYPECKQTAGQGS 1180
Score = 70.5 bits (171), Expect = 1e-11
Identities = 201/862 (23%), Positives = 273/862 (31%), Gaps = 216/862 (25%)
Query: 144 SPFDSIPDSELLVSPREGSSLHKLLTLSRTPPERD-----LITPVDPLGPSTGSSRGSGV 198
SP P+ L P E S L +PPE L TP+ P P S
Sbjct: 492 SPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSP--PPEASPLSPPF 549
Query: 199 EMSLPDPSWDFSPPSFLETSSPKLPSWR--PPRSRPRWGQSPPPQQRSDGEEEEE---VA 253
E S P PP L TS P S PP P SPPP++ E
Sbjct: 550 EESPLSP-----PPEELPTSPPPEASRLSPPPEESP---MSPPPEESPMSPPPEASRLFP 601
Query: 254 SFSGQILAGELDNCVSSIPDFPMHLACPEEEDKATAAEMAVPAAGDESISSLSELVRAMH 313
F L+ + S P L+ P E+ + P + +S LS L
Sbjct: 602 PFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSR 661
Query: 314 PYCLPNLTHLASLEDELQEQPDDLTLPEGCVVLEIVGQAATAGDDLEIPVVVRQVSPGPR 373
P + L+ +E P PE + + T+ + P SP P
Sbjct: 662 LSPPPEESPLSPPPEESPTSPP----PEASRLSPPPEDSPTSPPPEDSPA-----SPPPE 712
Query: 374 PVLLDDSLETSSALQLLMPTLESETEAAVPKVTLCSEKEGLSLNSEEKLDSACLLKPREV 433
L+ LE S L L + LC EG L+ PR
Sbjct: 713 DSLMSLPLEESPLLPL------------PEEPQLCPRSEGPHLS------------PR-- 746
Query: 434 VEPVVPKEPQNPPANAAPG-SQRARKGRKKKSKEQPAACVEGYARRLRSSSRGQSTVGTE 492
P+EP P P S +A + E+P C L + G
Sbjct: 747 -----PEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGP-----H 796
Query: 493 VTSQVDNLQKQPQEELQKESGPLQGKGKPRAWARAWAAALENSSPKNLERSAGQSSPAKE 552
++ Q + L PQ E + P+ + SP+ E SP E
Sbjct: 797 LSPQPEELHLSPQTE-EPHLSPVPEE--------------PCLSPQPEE---SHLSPQSE 838
Query: 553 GPLDLYPKLADTIQTNPIPTHLSL-VDSAQASPMPVDSVEADPTAVGPVLAGPVPVDPGL 611
P + P +HLS ++ SP P E P G P P + L
Sbjct: 839 EPC---------LSPRPEESHLSPELEKPPLSPRP----EKPPEEPGQC---PAPEELPL 882
Query: 612 VDLASTSSELVEPLPAEPVLINPVLADSAAVDPAVVPISDNLPPVDAVPSGPAPVDLALV 671
P P EP L +P+L + A +P P+S + PSG + L+
Sbjct: 883 F-----------PPPGEPSL-SPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLM 930
Query: 672 --DPVPNDLTPVDPVLVKSRPTDPRRGAVS---SALGGSAPQLLVESESLDPPKTIIPEV 726
DP+P L+P+ + + P G + A G S P+ + + L+ P + PE
Sbjct: 931 PPDPLPPPLSPI--ITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPE- 987
Query: 727 KEVVDSLKIESGTSATTHEARPRPLSLSEYRRRRQQRQAETEERSPQPPTGKWPSLPETP 786
A + P PP PS P +P
Sbjct: 988 --------------------------------------ANCTDPEPVPPMILPPS-PGSP 1008
Query: 787 TGLADIPCLVIPPAPAKKTALQRS---PETPLEICLVPVGPSPASPSPEPPVSKPVASSP 843
G A P L+ P P LQ S +P C P P PSP P+ K V S
Sbjct: 1009 VGPAS-PILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSV-PSPLSPIGKVVGVSD 1066
Query: 844 TEQVPSQEMPLLARPSPPVQSVSPAVPTPPSMSAALPFPAGGLGMPPSLPPPPLQ----- 898
++ E ++ P P PS ++ LP P G L P P P L
Sbjct: 1067 EAELHEMETEKVSEPECPALE--------PSATSPLPSPMGDLSCPAPSPAPALDDFSGL 1118
Query: 899 ------------PPSLP------------LSMGPVLPDPFTHYAPLPSWPCYP---HVSP 931
P S P L PVL DP AP+ YP +
Sbjct: 1119 GEDTAPLDGIDAPGSQPEPGQTPGSLASELKGSPVLLDP-EELAPVTPMEVYPECKQTAG 1177
Query: 932 SGYPC----------LPPPPTV 943
G PC P PPT+
Sbjct: 1178 QGSPCEEQEEPRAPVAPTPPTL 1199
Score = 60.5 bits (145), Expect = 1e-08
Identities = 136/566 (24%), Positives = 187/566 (33%), Gaps = 99/566 (17%)
Query: 756 YRRRRQQRQAETEERSPQPPTGKWPSLPETPTGLADIP----CLVIPPAPAKKTALQRSP 811
+R + Q+QAE++ Q G + P IP L PP A T SP
Sbjct: 2071 HRINKVQKQAESQINK-QTKVGDIARKTDRPALHLRIPPQPGALGSPPPAAAPTIFIGSP 2129
Query: 812 ETPLEICLVPVG----PSPASPSPEPPVSKPVASSPT--EQVPSQEMPLLARPSPPVQSV 865
TP + G P+ + P P+ P + P QVPSQ+ P P+ P++
Sbjct: 2130 TTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQVPAQVPSQD-PFGLAPAYPLE-- 2186
Query: 866 SPAVPTPPSMSAALPFPAGGLGMPPSLPPPPLQPPSLPLSMGPVLPDPFTHYAPLPSWPC 925
P PT P P P G P QPP L S P P + P P
Sbjct: 2187 -PRFPTAPPTYPPYPSPTGA----------PAQPPMLGASSRPGAGQPGEFHTTPPGTPR 2235
Query: 926 YPHVSPSGYPCLPPPPT-----VPLVSGTPGAYAVPPTCSVPWAPPPAPVSPYS------ 974
+ +P + P P+ VP G G A P S PPP S +
Sbjct: 2236 HQPSTPDPF-LKPRCPSLDNLAVPESPGVGGGKASEPLLS----PPPFGESRKALEVKKE 2290
Query: 975 ----STCTYGP--LGWGPGPQHAP------------FWSTVPP------PPLPPASIGRA 1010
S+ +YGP LG+ P F + + P P P +
Sbjct: 2291 ELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQ 2350
Query: 1011 VPQPKMESRGTPAGPPENVLPLSMAPPLSLGLPGHGAPQTEPTKVEVKPVPASPHPKHKV 1070
P P +P P+ P S P + P PQ P + +P P
Sbjct: 2351 EPPPAQALAPSPPSHPDIFRPGSYTDPYAQP-PLTPRPQPPPPE-SCCALPPRSLPSDPF 2408
Query: 1071 SALVQSPQMKALACVSAEGVTVEEPASERLKPETQETRPREKPPLPATKAVPTPRQSTVP 1130
S + SPQ ++ S +T ++E P PR + P P ++ P+ QS P
Sbjct: 2409 SRVPASPQSQSS---SQSPLTPRPLSAEAFCPSP--VTPRFQSPDPYSRP-PSRPQSRDP 2462
Query: 1131 KLPAVHPARLRKLSFLPTPRTQGSEDVVQA-FISEIGIEASDLSSLLEQFEKSEAKKECP 1189
P P PR Q E +A ++ + A + L E + P
Sbjct: 2463 FAPLHKP-----------PRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVP 2511
Query: 1190 ---PPAPADSLAVGNSGGVDIPQEKRPLDRLQAPELANVAGLTPPAT-----PPHQLWKP 1241
PP S G G P R P+ L PP PPH +
Sbjct: 2512 SGQPPNFVRSPGTGAFVGTPSPM------RFTFPQAVGEPSLKPPVPQPGLPPPHGINSH 2565
Query: 1242 LAAVSLLAKAKSPKSTAQEGTLKPEG 1267
L K +S T G P G
Sbjct: 2566 FGPGPTLGKPQSTNYTVATGNFHPSG 2591
Score = 52.8 bits (125), Expect = 3e-06
Identities = 121/471 (25%), Positives = 165/471 (35%), Gaps = 68/471 (14%)
Query: 846 QVPSQEMPLLARPSPPVQSVSPAVPTPPSMSAALPFPAGGLGMPPS-LPPPPLQPPSLPL 904
++P Q L + P ++ PT P A L A G PP+ P P P L L
Sbjct: 2105 RIPPQPGALGSPPPAAAPTIFIGSPTTP---AGLSTSADGFLKPPAGSVPGPDSPGELFL 2161
Query: 905 SMGPVLPDPFTHYAPLPSWPCYPHVSPSGYPCLPPPPTVPLVSGTPGAYAVPPTCSVPWA 964
+ P +P P P YP + P +P PPT P GA A PP
Sbjct: 2162 KLPPQVPAQVPSQDPFGLAPAYP-LEPR-FP--TAPPTYPPYPSPTGAPAQPPMLGASSR 2217
Query: 965 PPPAPVSPYSSTCTYGPLGWGPG-PQHAPFWSTVPP--PPLPPASIGRAVPQPKMESRGT 1021
P + +T PG P+H P ST P P P+ AVP ES G
Sbjct: 2218 PGAGQPGEFHTT--------PPGTPRHQP--STPDPFLKPRCPSLDNLAVP----ESPGV 2263
Query: 1022 PAGPPENVLPLSMAPPLSLGLPGHGAPQTEPTKVEVKPVPASPHPKHKVSALVQSPQMKA 1081
G PL PP G E K E+ S P + V SP
Sbjct: 2264 GGGKASE--PLLSPPPF-----GESRKALEVKKEELGASSPSYGPPN--LGFVDSPS--- 2311
Query: 1082 LACVSAEGVTVEEP--ASERLKPETQETRPREKPPLPATKAVPTPRQSTVPKLPAVHPAR 1139
+ G+ ++ P L P + P + P L P P Q+ P P+ HP
Sbjct: 2312 -SGTHLGGLELKTPDVFKAPLTPRASQVEP-QSPGLGLRPQEPPPAQALAPSPPS-HPDI 2368
Query: 1140 LRKLSFLP-------TPRTQGSEDVVQAFISEIGIEASDLSSLLEQFEKSEAKKECP-PP 1191
R S+ TPR Q + + SD S + +S++ + P P
Sbjct: 2369 FRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSL-PSDPFSRVPASPQSQSSSQSPLTP 2427
Query: 1192 APADSLAVGNSGGVDIPQEKRPLDRLQAPELANVAGLTPPATPPHQLWKPLAAVSLLAKA 1251
P + A P P R Q+P+ + PP+ P Q P A + +
Sbjct: 2428 RPLSAEAF-------CPSPVTP--RFQSPDPYS----RPPSRP--QSRDPFAPLHKPPRP 2472
Query: 1252 KSPKSTAQEGTLKPEGVTEAKHPAAVRLQEGVHGPSRVHVGSGDHDYCVRS 1302
+ P+ + G+L + PAA L G G V SG VRS
Sbjct: 2473 QPPEVAFKAGSLAHTSLGAGGFPAA--LPAGPAGELHAKVPSGQPPNFVRS 2521
Score = 47.0 bits (110), Expect = 2e-04
Identities = 61/249 (24%), Positives = 87/249 (34%), Gaps = 62/249 (24%)
Query: 770 RSPQPPTGKWPSLPETPTGLADIPCLVIPPAPAKKTALQRSPETPLEICLVPVGPSPASP 829
R PP +LP P L P +P +P +++ Q SP TP + PSP +P
Sbjct: 2386 RPQPPPPESCCALP--PRSLPSDPFSRVPASPQSQSSSQ-SPLTPRPLSAEAFCPSPVTP 2442
Query: 830 ---SPEP---PVSKPVAS---SPTEQVPSQEMPLLA-------------------RPSPP 861
SP+P P S+P + +P + P + P +A P+ P
Sbjct: 2443 RFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGP 2502
Query: 862 VQSVSPAVP------------------TPPSMSAALPFPAGGLGMPPSLPPPPLQPP--- 900
+ VP TP M P G + P +P P L PP
Sbjct: 2503 AGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGI 2562
Query: 901 SLPLSMGPVLPDPFTHYAPLPSWPCYPHVSPSGYPCLPPPPTVPLVSGTPGAYAVPPTCS 960
+ GP L P + + + +P SP G P T +Y + P
Sbjct: 2563 NSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLG----------PSSGSTGESYGLSPLRP 2612
Query: 961 VPWAPPPAP 969
PPPAP
Sbjct: 2613 PSVLPPPAP 2621
Score = 38.5 bits (88), Expect = 0.055
Identities = 111/465 (23%), Positives = 161/465 (34%), Gaps = 67/465 (14%)
Query: 504 PQEELQKESGPLQGKGKPRAWARAWAAALENSSPKNLERSAGQSSPAKEGPLDLYPKLAD 563
P + GP GKP++ + A N P G SS + L P
Sbjct: 2558 PPHGINSHFGPGPTLGKPQS--TNYTVATGNFHPSG--SPLGPSSGSTGESYGLSPLRPP 2613
Query: 564 TIQTNPIPT----HLSLVDSAQAS-PMPVDSVEADPTAVGPVLAG---PVPVDPGLVDLA 615
++ P P +LS S ++ PV+ E T +G LA P DPG+ L+
Sbjct: 2614 SVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLS 2673
Query: 616 STSSE-------LVEPLPAEPVLINPVLADSAAVDPAVVPISDNLPPVD--AVPSGPAPV 666
T E L E L + + N + + A + PP A PS PA
Sbjct: 2674 QTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVG---PPGSWGAEPSSPA-- 2728
Query: 667 DLALVDPVPNDLTPVDPVLVKSRPTDPRRGAVSSALGGSAPQLLVESESLD-PPKTIIPE 725
+ + TP KS +S + G P + L PP P
Sbjct: 2729 ----FEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPILG--PGSFPSDDRLSRPPPPATPS 2782
Query: 726 VKEVVDSLKIESGTSATTHEAR-PRPLSLSEYRRRRQQRQAETEERSPQ-PPTGKWPSLP 783
+V +S ++ G+ A A P L L + +++ Q+Q T S + + ++PS P
Sbjct: 2783 SMDV-NSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTP 2841
Query: 784 ETPTG-------LADIPCLVIPPAPAKKTALQRSPETPLEIC------LVPVG-PSPASP 829
G LA I + P P + P +E+ L P G P P
Sbjct: 2842 GPELGRQALGSPLAGISTRL--PGPGEPVPGPAGPAQFIELRHNVQKGLGPGGTPFPGQG 2899
Query: 830 SPEPPVSKPVASSPTEQVPSQEMPLLARPSPPVQSVSPAV--------PTPPSMSAALPF 881
P+ P PV+ P P L PP + +P PTP + LP
Sbjct: 2900 PPQRPRFYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNNSLHPTPHTKGPTLPT 2959
Query: 882 PAGGLGMPPSLP------PPPLQPPSLPLSMGPVLPDPFTHYAPL 920
+ PPS P L+ LP P L D F + L
Sbjct: 2960 GLELVNRPPSSTELGRPNPLALEAGKLPCE-DPELDDDFDAHKAL 3003
Score = 37.0 bits (84), Expect = 0.16
Identities = 38/135 (28%), Positives = 46/135 (34%), Gaps = 15/135 (11%)
Query: 772 PQPPTGKWPSLPETPTGLADIPCLVIPPAPAKKTALQRSPETPLEICLVPVGPSPASPSP 831
P P TG L P P PA AL P L PV P+P SP
Sbjct: 4267 PGPQTGPLQELGAGPRPQGP------PRLPAPPGALSTGP------VLGPVHPTPPPSSP 4314
Query: 832 EPPVSKPVASSPTEQVPSQEMPLLARPSPPVQSVSPAVPTPPSMSAALPFPAGGL---GM 888
+ P SP+ Q+P++ P P P P +S A A L G+
Sbjct: 4315 QEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGL 4374
Query: 889 PPSLPPPPLQPPSLP 903
P PP L P
Sbjct: 4375 GPWDPPDNLAETQKP 4389
Score = 37.0 bits (84), Expect = 0.16
Identities = 28/73 (38%), Positives = 32/73 (43%), Gaps = 6/73 (8%)
Query: 824 PSPASPSPEP-PVSKPVASSPTEQVPSQEMPLLARPSPPVQSVSPAVPTPPS---MSAAL 879
P P PSP P P++ AS PTE P E+P PPV S P +P S A
Sbjct: 4909 PPPEEPSPPPSPLAPSPASPPTE--PLVELPTEPLAEPPVPSPLPLASSPESARPKPRAR 4966
Query: 880 PFPAGGLGMPPSL 892
P G PP L
Sbjct: 4967 PPEEGEDSRPPRL 4979
Score = 36.6 bits (83), Expect = 0.21
Identities = 132/608 (21%), Positives = 184/608 (30%), Gaps = 160/608 (26%)
Query: 762 QRQAETEERSPQPPTGKWPSLPETPTG--LADIPCLVIPPAPAKKTALQRSPETPLEICL 819
QRQ + + Q P + P +P L P L P P Q P L
Sbjct: 4228 QRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGP------QTGPLQELGAGP 4281
Query: 820 VPVGPSPASPSPEPPVSKPVASSPTEQVPSQEMPLLARPSPPVQSVSPAVPTPPSMSAAL 879
P GP P P+P +S P P+PP P+ P P + L
Sbjct: 4282 RPQGP-PRLPAPPGALSTGPVLGP------------VHPTPP-----PSSPQEPKRPSQL 4323
Query: 880 PFPAGGLGMPPSLPPPPLQPPSLPLSMGPVLPDPFTHYAPLPSWPCYPHVSPSGYPCLPP 939
P P+ L LPP P P GP L PP
Sbjct: 4324 PSPSSQLPTEAQLPP---THPGTPKPQGPTLE--------------------------PP 4354
Query: 940 PPTVPLVSGTPGAYAVPPTCSV----PWAPP---PAPVSPYSSTCTYGPLGW--GPGPQH 990
P V +P A + T PW PP P S+ G L G
Sbjct: 4355 PGRV-----SPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQSSLVPGHLDQVNGQVVPE 4409
Query: 991 APFWSTVPPPPLPPASIGRAVPQPKMESRGTPAGPPENVLPLSMAPP------------- 1037
A S P P ++G K E+ G P G P L +A P
Sbjct: 4410 ASQLSIKQEPREEPCALG--AQSVKREANGEPIGAPGTSNHLLLAGPRSEAGHLLLQKLL 4467
Query: 1038 ------LSLG---------LPGH-------------GAPQTEPTKVEVKPVPASPHPKHK 1069
LS G + GH G P + KP+ P K
Sbjct: 4468 RAKNVQLSTGRGSEGLRAEINGHIDSKLAGLEQKLQGTPSNKEDAAARKPLTPKPKRVQK 4527
Query: 1070 VSALVQSPQMKALACVSAEGVTVEEPASERLKPETQETRPREKPPLPATKAVPTPRQSTV 1129
S + S + K +GV E ++LK E P +P + A ++ P S
Sbjct: 4528 ASDRLVSSRKKLR---KEDGVRASEALLKQLKQEL-SLLPLTEPAITANFSLFAPFGSGC 4583
Query: 1130 PKLPAVHPARLRKLSFLPTPRTQGSEDVVQAFISEIGIEASDLSSLLEQFEKSEAKKECP 1189
P LPT S+ + + +S S L
Sbjct: 4584 PVNGQSQLRGAFGSGALPTGPDYYSQLLTKNNLSNPPTPPSSL----------------- 4626
Query: 1190 PPAPADSLAVGNSGGVDIPQE--KRPLDRLQA----------PELANVAGLTPPATPPHQ 1237
PP P S+ GV +E + P D A E+ ++ L TPPH
Sbjct: 4627 PPTPPPSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTSEVKSLDLLAALPTPPHN 4686
Query: 1238 LWKPLAAVSLLAKAKSPKSTAQEGTLKPEGVTEAKHPAAVRLQEGVHGPSRVHVGSGDHD 1297
+ + + + E + P+ + A P ++ G P H+GSG +
Sbjct: 4687 ------------QTEDVRMESDEDSDSPDSIVPASSPESIL---GEEAPRFPHLGSGRWE 4731
Query: 1298 YCVRSRTP 1305
R+ +P
Sbjct: 4732 QEDRALSP 4739
Score = 35.4 bits (80), Expect = 0.47
Identities = 90/437 (20%), Positives = 132/437 (30%), Gaps = 130/437 (29%)
Query: 821 PVGPSPASPSPEPPV----------SKPVASSPTEQVPSQEMPLLARPSPPVQSVS--PA 868
P PS P+P P V S+ + P + +++ R + V+S+ A
Sbjct: 4620 PTPPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTSEVKSLDLLAA 4679
Query: 869 VPTPP-SMSAALPFPAGGLGMPPSLPPPPLQPPSLPLSMGPVLP--------------DP 913
+PTPP + + + + P P P S+ P P P
Sbjct: 4680 LPTPPHNQTEDVRMESDEDSDSPDSIVPASSPESILGEEAPRFPHLGSGRWEQEDRALSP 4739
Query: 914 FTHYAPLPSWPCYPHVSPSGYPCLPPPPTVPLVSGTPG---------------------- 951
P S P +P P G L P +P+ + G
Sbjct: 4740 VIPLIPRASIPVFPDTKPYGALGLEVPGKLPVTTWEKGKGSEVSVMLTVSAAAAKNLNGV 4799
Query: 952 --------AYAVPPTCSV--PWAPPPAPVSPYSSTCTYGPLGW-----GPGPQHAPFW-- 994
+ +P + V P +P A P GP G G P P W
Sbjct: 4800 MVAVAELLSMKIPNSYEVLFPESPARAGTEPKKGEAE-GPGGKEKGLEGKSPDTGPDWLK 4858
Query: 995 ---STVP------------------PPPLPPASIGRAVPQPKMESRGTPAGPPENVLPLS 1033
+ +P P P PP ++ R A PPE P
Sbjct: 4859 QFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSP-- 4916
Query: 1034 MAPPLSLGLPGHGAPQTEPTKVEVKPVPASPHPKHKVSALVQSPQMKALACVSAEGVTVE 1093
PP L P +P TEP VE+ P + P V
Sbjct: 4917 --PPSPLA-PSPASPPTEPL-VELPTEPLAEPP-------------------------VP 4947
Query: 1094 EPASERLKPETQETRPREKPPLPATKAVPTPRQSTVPKLPAVHPARLRKLSFLPTPR--- 1150
P PE+ +PR +PP + P P+L R ++L L T +
Sbjct: 4948 SPLPLASSPESARPKPRARPPEEGEDSRP-------PRLKKWKGVRWKRLRLLLTIQKGS 5000
Query: 1151 -TQGSEDVVQAFISEIG 1166
Q E V F+ ++G
Sbjct: 5001 GRQEDEREVAEFMEQLG 5017
Score = 33.5 bits (75), Expect = 1.8
Identities = 32/97 (32%), Positives = 41/97 (42%), Gaps = 19/97 (19%)
Query: 768 EERSPQPPTGKWPSLPETPTGLADIPCLVIPPAPAKKTALQRSPETPLEICLVPVGPSPA 827
E +P+PPT S + L D+ L PP P P P+ PSPA
Sbjct: 4882 ESPAPEPPTQH--SYTYNVSNL-DVRQLSAPPP--------EEPSPPPS----PLAPSPA 4926
Query: 828 SPSPEPPV---SKPVASSPT-EQVPSQEMPLLARPSP 860
SP EP V ++P+A P +P P ARP P
Sbjct: 4927 SPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKP 4963
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 855
Score = 96.3 bits (238), Expect = 2e-19
Identities = 150/563 (26%), Positives = 198/563 (35%), Gaps = 96/563 (17%)
Query: 741 ATTHEARPRPLSLSEYRRRRQQRQAETEERSPQPPTGKWPSLP-ETPTGLADIPCLVIPP 799
A H ++P+P L R Q + P G S P TP+ A + P
Sbjct: 265 APAHPSQPKPKGLQALR----PPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPT 320
Query: 800 APAKKTALQRSPETPLEICLVPVGPSPASPSPEPPVSKPVASSPTEQVPSQEMPLLARPS 859
PA +P + C + A PSP P S SP PSQ L S
Sbjct: 321 LPA-------TPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLG--S 371
Query: 860 PPVQSVSPAVPTPPSMSAALPFPAGGLGMPPSLPPPPLQPPSLPLSMGPVLPDPFTHYAP 919
P +Q+ +P+PP A P P PP+L PPLQ P
Sbjct: 372 PTLQATHSFLPSPPLSPLATPPPQA----PPALALPPLQAP------------------- 408
Query: 920 LPSWPCYPHVSPSGYPCLPPPPTVPLVSGTPGAYAVPPTCSV--PWAPPPAP-VSPYSST 976
PS P P +SP P P P V ++ PP+ V P++PP +P VSP ++
Sbjct: 409 -PSPPASPPLSPLATPS-PQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATP 466
Query: 977 CTYGPLGWGPGPQHAPFWSTVPP---PPLPPASIGRAVPQPKMESRGTPAGPPENVLPLS 1033
P AP PP PP PPAS P M TP PP+ PL+
Sbjct: 467 -----------PSQAPPSLAAPPLQVPPSPPAS-------PPMSPSATP--PPQAPPPLA 506
Query: 1034 MAPPLSLGLPGHGAPQTEPT-KVEVKPVPASPHPKHKVSALVQSPQMKALACVSAEGVTV 1092
APPL L P AP T ++ P P + P + S M LA + V
Sbjct: 507 -APPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPV 565
Query: 1093 ------EEPASERLKPETQETRPREKPPLPATKAVPTPRQSTVPKLPAVHPARLRK-LSF 1145
+ P S P Q R +PP P + + T+ P P R S
Sbjct: 566 LAAPLLQVPPSPPASPTLQAPR---RPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSST 622
Query: 1146 LPTPRTQGSEDVVQAFISEI-GIEASDLSSLLEQFEKSEAKKECPPPA----PADSLAVG 1200
L P G + E+ G ++ C P A PA LA
Sbjct: 623 LSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFR 682
Query: 1201 NSGGVDIPQEKR----------PLDRLQAPELANVA--GLTPPATPPHQLWKPLAAVSLL 1248
+ G +P + + PE A A L P +P K A
Sbjct: 683 GAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAG 742
Query: 1249 AKAKSPKSTAQEGTLKPEGVTEA 1271
A ++SPK A+ G L P G +A
Sbjct: 743 ASSRSPKQ-ARLGEL-PLGALQA 763
Score = 86.7 bits (213), Expect = 2e-16
Identities = 147/547 (26%), Positives = 190/547 (34%), Gaps = 83/547 (15%)
Query: 513 GPLQGKGKPRAWARAWAAALENSSPKNLERSAGQSSPAKEGPLDLYPKLADTIQTNPIPT 572
GPL KG + A +PK SAG GP P A ++ T
Sbjct: 127 GPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTS-GPTPGTPSPAMARRSRAAGT 185
Query: 573 HLSLVDSAQASPMPVDSVEADPTAVGPVLAGPVPVDPGLVDLASTSSELVEPLPAEPVLI 632
+ L P P S P GP + V AS S EP PA
Sbjct: 186 EVGL-------PRPAPSARPRPPTEGPRKS---------VSSASEHST-TEPSPAAR--- 225
Query: 633 NPVLADSAAVDPAVVPISDNLPPVDA-VPSGPAPVDLALVDPVPNDLTPVDPVLVKSRPT 691
A PA +S + P+ + SGP+ P+ P ++
Sbjct: 226 RRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQV 285
Query: 692 DPRRGAVSSALGG-SAPQLLVESESLDPPKTIIPEVKEVVDSLKIESGTSATTHEARPRP 750
P R + ALG S+ L S S P + S +S T A P P
Sbjct: 286 TPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHS------SSLTCQLATPLP 339
Query: 751 LSLSEYRRRRQQRQAETEERSPQPPTGKWPSLPETPTGLADI----PCLVIP----PAPA 802
L+ S P PS P TP A P L P+P
Sbjct: 340 LA--------------PPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPP 385
Query: 803 KKTALQRSPETPLEICLVPVGPSPASPSPEPPVSKPVASSPTEQVPSQ------EMPLLA 856
P+ P + L P+ +P SP PP+S P+A+ P+ Q P+ + P
Sbjct: 386 LSPLATPPPQAPPALALPPL-QAPPSPPASPPLS-PLAT-PSPQAPNALAVHLLQAPFSP 442
Query: 857 RPSPPVQS-VSPAVPTPPSMSAALPFPAGGLGMPPSLPPPPLQPPSLPLSMGPVLPDPFT 915
PSPPVQ+ SP P S SA PPS PP L P L + P P +
Sbjct: 443 PPSPPVQAPFSPPASPPVSPSAT----------PPSQAPPSLAAPPLQVPPSPPASPPMS 492
Query: 916 HYA-PLPSWPCYPHVSPSGYPCLPPPPTVPLVSGTPGAYAVP-PTCSVPWAPPPAPVSPY 973
A P P P P ++ PPP P TP A+P P S P P +P
Sbjct: 493 PSATPPPQAP--PPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSP---- 546
Query: 974 SSTCTYGPLGWGPGPQHAPFWST--VPPPPLPPASIGRAVP-QPKMESRGTPAGPPENVL 1030
S++ PL P PQ P + + PP PPAS P +P T P L
Sbjct: 547 SASLPMSPLA-TPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTL 605
Query: 1031 PLSMAPP 1037
L+ PP
Sbjct: 606 ALAPGPP 612
Score = 52.4 bits (124), Expect = 4e-06
Identities = 171/790 (21%), Positives = 246/790 (31%), Gaps = 190/790 (24%)
Query: 771 SPQPPTGKWPSLPETPTGLADIPCLVIPPAPAKKTALQRS--------PETPLEICLVPV 822
+P+PP P P TP L L A +K +R+ PE+
Sbjct: 26 TPRPPGSPRPPPPVTPAALR---VLGAAGAVGRKPLAERAGGIGGATIPESAPR-----A 77
Query: 823 GPS-PASPSPEPPVSKPVASSPTEQVPSQEMPLLARPSPPVQSVSPAVPTPPSMSAAL-- 879
GP+ A S P S+P AS E+ +PP ++ SP + P ++
Sbjct: 78 GPTRSAGTSSRNPASRPPASGRGER------------APPAKNTSPGPVSSPGRASGTTR 125
Query: 880 PFPAGGLGMPPSLPPPPLQ------PPSLPLSMGPVLPDPFTHYAPLPSWPCYPHVSPSG 933
P P G G+ S + P LS G P P P
Sbjct: 126 PGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTS----GPTPGTPS-------- 173
Query: 934 YPCLPPPPTVPLVSGTPGAYAVPPTCSVPWAPPPAPVSPYSSTCTYGPLGWGPGPQHAPF 993
P +GT P + P P P SS + P + P
Sbjct: 174 ----PAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPS 229
Query: 994 WSTVPPPPLPPASIGRAVP-----QPKMESRGTPAGPPENVLPLSMAPPLSLGLPGHGAP 1048
P + A P + +RGTP P + P GL P
Sbjct: 230 AGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHP------SQPKPKGLQALRPP 283
Query: 1049 QTEPTKVEVKP----VPASPHPKHKVSALVQS---------PQMKALACVSAEGVTVEEP 1095
Q P + + P + +SP SA +QS P +L C A + + P
Sbjct: 284 QVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPP 343
Query: 1096 ASERLKPETQETRPREKPPLPATKAVPTPRQSTV----PKLPAVHPARLRKLSFLPTPRT 1151
+ + P LP+ A P P Q+T P L A H SFLP+P
Sbjct: 344 SP---------SAPPSLQTLPSPPATP-PSQATTSLGSPTLQATH-------SFLPSP-- 384
Query: 1152 QGSEDVVQAFISEIGIEASDLSSLLEQFEKSEAKKECPPPAPADSLAVGNSGGVDIPQEK 1211
LS L PPP +LA+ P
Sbjct: 385 -------------------PLSPLAT-----------PPPQAPPALALPPLQAPPSPPAS 414
Query: 1212 RPLDRL-----QAPELANV----AGLTPPATPPHQLWKPLAAVSLLAKAKSPKSTAQEGT 1262
PL L QAP V A +PP +PP Q A ++ + +P S A
Sbjct: 415 PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSL 474
Query: 1263 LKPEGVTEAKHPAAVRLQEGVHGPSRVHVGSGDHDYCVRSRTPPKKMPALVIPEVGSRWN 1322
P PA+ + PS + PP+ P L P +
Sbjct: 475 AAPPLQVPPSPPASPPMS-----PS--------------ATPPPQAPPPLAAPPLQ---- 511
Query: 1323 VKRHQDITIKPVLSLGPAAPPPPCIAASREPLDHRTSSEQADPSAPCLAPSSLLSPEASP 1382
KP PA PP A P + + ++ ++P + P+A P
Sbjct: 512 -------LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPP 564
Query: 1383 CRNDMNTRTPPEPSAKQRSMRCYRKACRSASPSSQGWQGRRGRNSRSVSSGSNRTSEASS 1442
+ PP P ASP+ Q RR +S S +
Sbjct: 565 VLAAPLLQVPPSP---------------PASPTLQA--PRRPPTPGPDTSVSGPRLTLAL 607
Query: 1443 SSSSSSSSSRSRSRSLSPPHKRWRRSSCSSSGRSRRCSSSSSSSSSSSS----SSSSSSS 1498
+ SRS S +LS P SS +S+ R S +++S + ++
Sbjct: 608 APGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACH 667
Query: 1499 SRSRSRSPSP 1508
+ SR P+P
Sbjct: 668 PAAWSRGPAP 677
>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
Length = 1427
Score = 95.9 bits (237), Expect = 3e-19
Identities = 177/649 (27%), Positives = 233/649 (35%), Gaps = 116/649 (17%)
Query: 534 NSSPKNLERSAGQSSPAKEGPLDLYPKLADTIQTNPIPTHLSLVDSAQASPMPVDSVEAD 593
N P+ AG + P E + P L +T +PT +D+A SP S+ A
Sbjct: 807 NIFPEKQVTKAGNTEPVLE---EWIPVLQRPSRTAAVPTVKDALDAALPSPEEGTSIAAV 863
Query: 594 PTAVG-PVLAGPVPVDPGLVDLASTSSELVEPLPAEPVLINPVLADSAAVDPAVVPISDN 652
P G V+A VP + +AS S L E V V A A PAV
Sbjct: 864 PAPEGTAVVAALVPFPHEDILVASIVS-----LEEEDVTAAAVSAPERATVPAVTV---- 914
Query: 653 LPPVDAVPSGPAPVDLALVDPVPNDLTPVDPVLVKSRPTDPRRGAVSSALGGSAPQLLVE 712
+VP G A V A V P + P + SA+ G +P+
Sbjct: 915 -----SVPEGTAAV--AAVSS-PEETAPAVAAAITQEG--------MSAVAGFSPEWAAL 958
Query: 713 SESLDPPKTIIPEVKEVVDSLKIESGTSATTHEARPRP----LSLSEYRRRRQQRQAETE 768
+ +P +E D T ATT A P + +S A
Sbjct: 959 A-------ITVPITEE--DGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPT 1009
Query: 769 ERSPQPPTGKWPSLPETPTGLADIPCLVIPPAPAKKTALQRSPETPLEICLVPVGPSPAS 828
P P P+ PE PT P +PP P + T+ + TP E P P+ A
Sbjct: 1010 PEEPTSPAAAVPT-PEEPTS----PAAAVPP-PEEPTSPAAAVPTPEE----PTSPAAAV 1059
Query: 829 PSPEPPVSKPVASSPTEQVPSQEMPLLARPSPPVQSVSPAVPT---PPSMSAALPFPAGG 885
P+PE P S P A+ PT + P+ + P P S + AVPT P S +AA+P P
Sbjct: 1060 PTPEEPTS-PAAAVPTPEEPTSPAAAVPTPEEPT-SPAAAVPTPEEPTSPAAAVPTPE-- 1115
Query: 886 LGMPPSLPPPPLQPPSLPLSMGPVLPDPFTHYAPLPSWPCYPHVSPSGYPCLPPPPTVPL 945
P+ P + P P S +P P P P+ P P S S +P P
Sbjct: 1116 ---EPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPT-PEESASAAVAVPTPEE--- 1168
Query: 946 VSGTPGAYAVPPTCSVPWAPPPA----PVSPYSSTCTYGPLGWGPGPQHAPFWSTVPPPP 1001
S +P A P S +A A P SP +S T P + + P
Sbjct: 1169 -SASPAAAVPTPAESASFAAVVATLEEPTSPAASVPT--PAAMVATLEEFTSPAASVPTS 1225
Query: 1002 LPPASIGRAVPQPKMESRGTPAGPPENVLPLSMA----PPLSLGLPGHGAPQTEPTKVEV 1057
PAS+ AV P+ E A P P S A P L P P E
Sbjct: 1226 EEPASLAAAVSNPE-EPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEE----- 1279
Query: 1058 KPVPASPHPKHKVSALVQSPQMKALACVSAEGVTVEEPASERLKPETQETRPREKPPLPA 1117
PASP A VS +EEPAS T E +PA
Sbjct: 1280 ---PASP-----------------AAAVS----NLEEPASPAAAVPTPEV-----AAIPA 1310
Query: 1118 TKAVPTPRQSTVPKLPAVHPARLRKLSFLPTPRTQGSEDVVQAFISEIG 1166
+VPTP VP +PA + ++S + P S ISE G
Sbjct: 1311 A-SVPTPE---VPAIPAAAVPPMEEVSPIGVPFLGVSAHTDSVPISEEG 1355
Score = 70.9 bits (172), Expect = 1e-11
Identities = 111/464 (23%), Positives = 148/464 (31%), Gaps = 81/464 (17%)
Query: 526 RAWAAALENSSPKNLERSAGQSSPAKEGPLDLYPKLADTIQTNPIPTHLSLVDSAQASPM 585
RA A+ S P+ A SSP + P +A I + A +
Sbjct: 906 RATVPAVTVSVPEGTAAVAAVSSPEETAPA-----VAAAITQEGMSAVAGFSPEWAALAI 960
Query: 586 PVDSVEADPTAVGPVLAGPVPVDPGLVDLA----STSSELVEPLPAEPVLINPVLADSAA 641
V E D T GPV P D A ST E P A P P +A
Sbjct: 961 TVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAV 1020
Query: 642 VDP--------AVVPISDNLPPVDAVPSGPAPVDLALVDPVPNDLT-PVDPVLVKSRPTD 692
P AV P + P AVP+ P A P P + T P V PT
Sbjct: 1021 PTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTS 1080
Query: 693 PRRGAVSSALGGSAPQLLVESESLDPPKTIIPEVKEVVDSLKIESGTSATTHEARPRPLS 752
P + S + E P +P +E A+ A P P
Sbjct: 1081 PAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEE-----------PASPAAAVPTP-- 1127
Query: 753 LSEYRRRRQQRQAETEERSPQPPTGKWPSLPETPTGLADIPCLVIPPAPAKKTALQRSPE 812
+ A P P +P+ P PT V P P + + +
Sbjct: 1128 ---------EEPASPAAAVPTPEEPAFPA-PAVPTPEESASAAVAVPTPEESASPAAAVP 1177
Query: 813 TPLEICLV---------PVGPSPASPSPEPPVS------KPVASSPTEQVPSQEMPLLAR 857
TP E P P+ + P+P V+ P AS PT + P+ ++
Sbjct: 1178 TPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSN 1237
Query: 858 PSPPVQSVSPAVPT--PPSMSAALPFPAGGLGMPPSLPPPPLQP------------PSLP 903
P P S + AVPT P+ SAA L P + P P +P P+ P
Sbjct: 1238 PEEPT-SPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASP 1296
Query: 904 LSMGPV----------LPDPFTHYAPLPSWPCYPHVSPSGYPCL 937
+ P +P P P + P VSP G P L
Sbjct: 1297 AAAVPTPEVAAIPAASVPTPEVPAIPAAAVPPMEEVSPIGVPFL 1340
>gi|91982772 mucin 17 [Homo sapiens]
Length = 4493
Score = 94.7 bits (234), Expect = 6e-19
Identities = 289/1416 (20%), Positives = 464/1416 (32%), Gaps = 236/1416 (16%)
Query: 140 SENLSPFDSIPDSELLVSPREGSSLHKLLTLSRTPPERDLITPVDPLGPSTGSSRGSGVE 199
SE +P S+P S + V E S+ TPVD P T S+ S
Sbjct: 2393 SEGSTPLTSVPVSTMPVVSSEAST--------------HSTTPVDTSTPVTTSTEASSSP 2438
Query: 200 MSLPDPSWDFSPPSFLETSSPKLPSWRPPRSRPRWGQSPPPQQRSDGEEEEEVASFSGQI 259
+ S SPPS T +P P V+S +G +
Sbjct: 2439 TTAEGTSIPTSPPSEGTTPLASMPVSTTP----------------------VVSSEAGTL 2476
Query: 260 LAGELDNCVSSIPDFPMHLACPEEEDKATAAEMAVP-AAGDESISSLSELVRAMHPYCLP 318
+D PM + TA ++ VP + E + L+ + + P P
Sbjct: 2477 STTPVDTST------PMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASP 2530
Query: 319 NLTHLASLEDELQEQPDDLTLPEGCVVLEIVGQAATAGDDLEIPVVVRQVSPGPRPVLLD 378
+ L++ P D P V + +AT+ + +P P +
Sbjct: 2531 EASTLSTT-------PVDSNSP--VVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPV 2581
Query: 379 DSLETSSALQLLMPTLESETEAAVPKVTLCSEKEGLSLNSEEKLDSACLLKPREVVEPVV 438
+ +S+ + T +T V T E S + K S + P EV +
Sbjct: 2582 STKPLASSEASTLSTTPVDTSIPVTTST-----ETSSSPTTAKDTSMPISTPSEVSTSLT 2636
Query: 439 PKEPQNPPANAAPGSQRARKGRKKKSKEQPAACVEGYARRLRSSSRGQSTVGTEVTSQVD 498
P ++ S + ++ + SS ST G E ++ +
Sbjct: 2637 SILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPG-ERSTPLT 2695
Query: 499 NLQKQPQEELQKESGPLQGKGKPRAWARAWAAALENSSPKNLERSAGQSSPAKEGPLDLY 558
N+ E+ L + +A +SSP E ++ + S +G L
Sbjct: 2696 NILVSTTLLANSEASTLSTTPVDTS-TPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLT 2754
Query: 559 PKLADTIQTNPIPTHLSLVDSAQASPMPVDSVEADPTAVGPVLAGPVPVDPGLVDL-AST 617
L T+ V S++AS + +V+ A P + + ST
Sbjct: 2755 SILVSTLP----------VASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTST 2804
Query: 618 SSELVEPLPAEPVLINPVLADSAAVDPAVVPISDNLP----------PVDA----VPSGP 663
SE PL + PV PV A S A + P+ + P P A VP
Sbjct: 2805 PSETSTPLTSMPVNHTPV-ASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPIST 2863
Query: 664 APVDLALVDPVPNDLTPV---DPVLVKSRPTDPRRGAVSSALGGSAPQLLV-ESESLDPP 719
A L+ +P TPV + + + P D +S G S+P S + P
Sbjct: 2864 ASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTP 2923
Query: 720 KTIIPEVKEVVDSLKIESGTSATTHEARPRPLSLSEYRRRRQQRQAETEERSPQPPTGKW 779
+ + ++ S +G+ A+T P + R+P + +
Sbjct: 2924 SEVSTPLTSILVSTVPVAGSEASTLSTTP------------------VDTRTPVTTSAEA 2965
Query: 780 PSLPETPTGLADIPCLVIPPAPAKKTALQRSPETPLEICLVPVGPSPASPSPEPPVSKPV 839
S P T G + P +R+P T + + +PV S AS P
Sbjct: 2966 SSSPTTAEGTS---------MPISTPGERRTPLTSMSVSTMPVASSEASTLSRTP----- 3011
Query: 840 ASSPTEQVPSQEMPLLARPSPPVQSVSPAVPTPPSMSAALPFPAGGLGMPPSLPPPPLQP 899
A S PV + + A +P + A G G+P S P P
Sbjct: 3012 ----------------ADTSTPVTTSTEASSSPTT--------AEGTGIPISTPSEGSTP 3047
Query: 900 -PSLPLSMGPVLPDPFTHYAPLPSWPCYPHVSPSGYPCLPPPPTVPLVSGTPGAYAVPPT 958
S+P+S PV + + P P V+ + P P GT +
Sbjct: 3048 LTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTP-----AEGTSMPISTYSE 3102
Query: 959 CSVPWAPPPAPVSPYSSTCTYGPLGWGPGPQHAPFWSTVPPPPLPPASIGRAVPQPKMES 1018
S P P +P +S+ L P P ++ P S G ++P
Sbjct: 3103 GSTPLTGVPVSTTPVTSSAI-STLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSE 3161
Query: 1019 RGTPAG--PPENVLPLSM------APPLSLGLPGHGAPQ-TEPTKVEVKPVPASPHPKHK 1069
TP P +L +S A P+ P + + T T E +P S P
Sbjct: 3162 GSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTST-PSEG 3220
Query: 1070 VSALVQSPQMKALACVSAEGVTVEEPASERLKPETQETRPREKPPLPATKAVPT--PRQS 1127
++ L P S + P P T T PP ++PT P +
Sbjct: 3221 MTPLTSVPVSNTPVASSEASILSTTPVDSNT-PLTTSTEASSSPPTAEGTSMPTSTPSEG 3279
Query: 1128 TVPKLPAVHPARLRKLSFLPTPRTQGSEDVVQAFISEIGIEASDLSSLLEQFEKSEAKKE 1187
+ P L+ +P T V + S + +D S+ + + ++ +
Sbjct: 3280 STP------------LTSMPVSTTT----VASSETSTLSTTPADTSTPVTTYSQASSS-- 3321
Query: 1188 CPPPAPADSLAVGNSGGVDIPQEKRPLDRLQAPELANVAGLTPPATPPHQLWKPLAAVSL 1247
PP A S+ P L N++ T P V
Sbjct: 3322 -PPIADGTSMPTSTYSEGSTP-------------LTNMSFSTTPVVSSEASTLSTTPVD- 3366
Query: 1248 LAKAKSPKSTAQEGTLKPEGVTEAKHPAAVRLQEGVHGPSRVHVGSGDHDYCVRSRTPPK 1307
+P +T+ E +L P P + PS TP
Sbjct: 3367 ---TSTPVTTSTEASLSPTTAEGTSIPTS--------SPSE-------------GTTPLA 3402
Query: 1308 KMPALVIPEVGSRWNVKRHQDITIKPVLSLGPAAPPPPCIAASREPLDHRTSSEQADP-S 1366
MP P V S N + +++ A P IA L T+SE + P S
Sbjct: 3403 SMPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTS-LPTSTTSEGSTPLS 3461
Query: 1367 APCLAPSSLLSPEASP-CRNDMNTRTPPEPSAKQRSMRCYRKACRSASPSSQGWQGRRGR 1425
L+ + + S EAS ++T TP S+ S + ++ P+S +G
Sbjct: 3462 IMPLSTTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEV--TSMPTSTAGEGSTPL 3519
Query: 1426 NSRSVSSGSNRTSEASSSSS---------SSSSSSRSRSRSLSPPHKRWRRSSCSSSGRS 1476
+ VS+ +SEAS+ S+ +SSS + S +L R S SS +
Sbjct: 3520 TNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLT 3579
Query: 1477 RRCSSSSSSSSSSSSSSSSSSSSRSRSRSPSPRRRS 1512
SS+ +SS +S+ S+ S RS + S + S
Sbjct: 3580 TMLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNS 3615
Score = 79.3 bits (194), Expect = 3e-14
Identities = 230/1033 (22%), Positives = 372/1033 (36%), Gaps = 159/1033 (15%)
Query: 535 SSPKNLERSAGQSSPAKEG--PLDLYP--------KLADTIQTNPIPTHLSLVDSAQAS- 583
SSP E ++ +S EG PL P A T+ T P+ ++ L S +AS
Sbjct: 963 SSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASS 1022
Query: 584 PMPVDSVEADPTAVGPVLAGPV---PVDPGLVDLASTSSELVEPLPAEPVLINPVLADSA 640
P P + PT+ + P+ PV +V + TS+ P + A S+
Sbjct: 1023 PPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSS 1082
Query: 641 AVDPAVVPISDNLPPVDAVPSGPAPVDLALV---DPVPNDLTPVD---PVLVKSRPTDPR 694
+ + + + P PV LV + TPVD PV + +
Sbjct: 1083 STTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSP 1142
Query: 695 RGAVSSALGGSAPQLLVESESLDPPKTIIPEVKEVVDSLKIESGTSATTHEARPRPLSLS 754
A +++ S P SE P ++ VV S E+ T +TT P+
Sbjct: 1143 TTAEGTSIPTSPP-----SEGTTPLASMPVSTTLVVSS---EANTLSTT------PVD-- 1186
Query: 755 EYRRRRQQRQAETEERSPQPPTGKWPSLP-----ETPTGLADIPCLVIPPAPAKKTALQR 809
+ Q TE SP PPT + S+P E T L +P P A ++ + L
Sbjct: 1187 ----SKTQVATSTEASSP-PPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLST 1241
Query: 810 SP---ETPLEICLVPVGPSPASPSPEPPVSKPVASSPTEQVPSQEMP----LLARP---- 858
SP TP + + +SP+ S P +++ +P L+ P
Sbjct: 1242 SPVDTSTP----VTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSPEAST 1297
Query: 859 --SPPVQSVSPAVPTPPSMSAALPFPAGGLGMPPSLPPPPLQP-PSLPLSMGPVLPDPFT 915
+ PV + P V + S+ P PA G MP S P S+P++ V +
Sbjct: 1298 LLTTPVDTKGPVVTSNEVSSS--PTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAIS 1355
Query: 916 HYAPLPSWPCYPHVSPSGYPCLPPPPT--VPLVSGTPGAYAVPPTCSVPWAPPPAPVSPY 973
+ P P V+ S C P + + + P P T S+P + P VS
Sbjct: 1356 ILSTTPVDNSTP-VTTSTEACSSPTTSEGTSMPNSNPSEGTTPLT-SIPVSTTPV-VSSE 1412
Query: 974 SSTCTYGPLGWG-PGPQHAPFWSTVPPPPLPPASIGRAVPQPKMESRGTPAGPPENVLPL 1032
+ST + P+ PG A S+ P + G ++P + P E PL
Sbjct: 1413 ASTLSATPVDTSTPGTTSAEATSS------PTTAEGISIP---------TSTPSEGKTPL 1457
Query: 1033 SMAPPLSLGLPGHGAPQTEPTKVEVK-------PVPASPHPKHKVSALVQSPQMKALACV 1085
P + + A T V+ V +SP P S + +P + A
Sbjct: 1458 KSIPVSNTPVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALT 1517
Query: 1086 SAEGVTVEEPASERLKPETQETRPREKPPLPATKAVPTPRQSTVPKLPAVHPARLRKLSF 1145
S T +SE T PA + P S P S
Sbjct: 1518 SIPVSTTTVASSEINSLST----------TPAVTSTPVTTYSQASSSPTTADG----TSM 1563
Query: 1146 LPTPRTQGSEDVVQAFISEIGIEASDLSSLLEQFEKSEAKKECPPPAPADSLAVGNSGGV 1205
+ ++GS + +S + + +S+ ++L S+ + A + + A G+S +
Sbjct: 1564 QTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTI 1623
Query: 1206 DIPQEKRPLDRLQAPELANVAGLTPPATPPHQLWKPLAAVSLLAKAKSPKSTAQEGTLKP 1265
P E PL L ++ T P P V + SP T+ E
Sbjct: 1624 STPSEGSPL-------LTSIPVSTTPVASPEASTLSTTPVD----SNSPVITSTE----- 1667
Query: 1266 EGVTEAKHPAAVRLQEGVHGPSRVHVGSGDHDYCVRSRTPP---KKMPALVIPEVGSRWN 1322
V+ + PA EG P+ + + RT P + L V +
Sbjct: 1668 --VSSSPTPA-----EGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLSTTPVDNSTP 1720
Query: 1323 VKRHQDITIKPVLSLGPAAPPPPCIAASREPLDHRTSSEQADP--SAPCLAPSSLLSPEA 1380
V + P S G + P + T SE P S P ++ + +LS EA
Sbjct: 1721 VTTSTEARSSPTTSEGTSMP-------------NSTPSEGTTPLTSIP-VSTTPVLSSEA 1766
Query: 1381 SP-CRNDMNTRTPPEPSAKQRSMRCYRKACRSASPSSQGWQGRRGRNSRSVSSGSNRTSE 1439
S ++T TP S + S + ++ P+S +G S VS SE
Sbjct: 1767 STLSATPIDTSTPVTTSTEATSSPTTAEG--TSIPTSTLSEGMTPLTSTPVSHTLVANSE 1824
Query: 1440 ASS------SSSSSSSSSRSRSRSLSPPHKRWRRSSCSSSGRSRRCSSSSSSSSSSSSSS 1493
AS+ S+S +S + S S +P +S S G + S S+++ +SS +
Sbjct: 1825 ASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSET 1884
Query: 1494 SSSSSSRSRSRSP 1506
++ S++ + + +P
Sbjct: 1885 NTLSTTPAVTSTP 1897
Score = 63.2 bits (152), Expect = 2e-09
Identities = 207/1015 (20%), Positives = 342/1015 (33%), Gaps = 157/1015 (15%)
Query: 534 NSSPKNLERSAGQSSPAKEG--PLDLYPKLADTIQTNPIPT-HLSLVDS---------AQ 581
+SSP + S+ +S +EG PL P T+ ++ I T +L D+ A
Sbjct: 1905 SSSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVASSEINTLSTTLADTRTPVTTYSQAS 1964
Query: 582 ASPMPVDSVEADPTAV--GPVLAGPVPVDPGLVDLASTSSELVEPLPAEPVLINPVLADS 639
+SP D A G +P+ LV + S+ P+ S
Sbjct: 1965 SSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSS 2024
Query: 640 AAVDPAVVPISDNLPPVDAVPSGPAPVDLALVDPVPNDLTPVDPVLVKSRPTDPRRGAVS 699
+ I + P P PV LV + PV K++ T+ + S
Sbjct: 2025 SPTTAGGTSIQTSTPSERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSS 2084
Query: 700 SALGGSAPQLLVESESLDPPKTIIPEVKEVVDSLKIESGTSATTHEARPRPLSLSEYRRR 759
+ GS+ + SE P T IP +TT A P
Sbjct: 2085 ATAEGSSMTISAPSEG-SPLLTSIP---------------LSTTPVASP----------- 2117
Query: 760 RQQRQAETEERSPQPPTGKWPSLPETPTGLADIPCLVIPPAPAKKTALQRSPETPLEICL 819
E S P P + T + P P + T++Q S +
Sbjct: 2118 ------EASTLSTTPVDSNSPVITSTEVSSS--------PIPTEGTSMQTSTYS------ 2157
Query: 820 VPVGPSPASPSPEPPVSKPVASSPTEQVPSQEMPLLARPSPPVQSVSPAVPTPPSMSAAL 879
+P PVS V +S S + PV + +P + + S+
Sbjct: 2158 -----DRRTPLTSMPVSTTVVASSAISTLS---------TTPVDTSTPVTNSTEARSS-- 2201
Query: 880 PFPAGGLGMPPSLPPPPLQP-PSLPLSMGPVLPDPFTHYAPLP---SWPCYPHVSPSGYP 935
P + G MP S P P S+P+S PV+ + + P S P + P
Sbjct: 2202 PTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSP 2261
Query: 936 CLPPPPTVPLVSGTPGAYAVPPTCSVPWAPPPAPVSPYSSTCTYGPLGWGPGPQHAPFWS 995
++P + + G P S+P + S S+ T P + PF +
Sbjct: 2262 TTAEGTSIPTSTLSEG---TTPLTSIPVSHTLVANSEVSTLST------TPVDSNTPFTT 2312
Query: 996 TVPPPPLPPASIGRAVPQPKMESRGTPAG--PPENVL-------PLSMAP-PLSLGLPGH 1045
+ PP + G ++P TP P + LS P S + +
Sbjct: 2313 STEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTY 2372
Query: 1046 GAPQTEPTKVEVKPVPASPHPKHKVSALVQSPQMKALACVSAEGVTVEEPASERLKPETQ 1105
+ PT + +P S + + S + S + + VS+E T + P T
Sbjct: 2373 SQAGSSPTTADDTSMPTSTYSEG--STPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTT 2430
Query: 1106 ETRPREKPPLPATKAVPT--PRQSTVP--KLPA----VHPARLRKLSFLP----TPRTQG 1153
T P ++PT P + T P +P V + LS P TP T
Sbjct: 2431 STEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTS 2490
Query: 1154 SEDVVQAFISEIGI----EASDLSSLLEQFEKSEAKKECPPPAPADSLAVGNSGGV---- 1205
+E +E + AS+ S+LL S P + + V ++ V
Sbjct: 2491 TEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSNSPVVTST 2550
Query: 1206 DIPQEKRPLDRLQAPELANVAGLTPPATPPHQLWKPLAAVSLLAKAKSPKSTAQEGTLKP 1265
+I + P G TP + P KPLA+ + +P T+ T
Sbjct: 2551 EISSSATSAEGTSMPTSTYSEGSTPLRSMPVST-KPLASSEASTLSTTPVDTSIPVTTST 2609
Query: 1266 EGVTEAKHPAAVRLQEGVHGPSRVHVGSGDHDYCVRSRTPPKKMPALVIPEVGSRWNVKR 1325
E T + A + PS V T + +P S +
Sbjct: 2610 E--TSSSPTTAKDTSMPISTPSEV-------------STSLTSILVSTMPVASSEASTLS 2654
Query: 1326 HQDITIKPVLSLGPAAPPPPCIAASREPLDHRTSSEQADPSAPCLAPSSLL--SPEASPC 1383
+ + +++ P A + T E++ P L ++LL S ++
Sbjct: 2655 TTPVDTRTLVTTSTGTSSSP-TTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEASTLS 2713
Query: 1384 RNDMNTRTPPEPSAKQRSMRCYRK--ACRSASPSSQGWQGRRGRNSRSVSSGSNRTSEAS 1441
++T TP SA+ S + + R ++PS G S VS+ +SEAS
Sbjct: 2714 TTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPS----DGSTPLTSILVSTLPVASSEAS 2769
Query: 1442 SSSSSSSSSSRSRSRSLSPPHKRWRRSSCSSSGRSRRCSSSSSSSSSSSSSSSSS 1496
+ S+++ +S + S + SSS + +S +S+ S +S+ +S
Sbjct: 2770 TVSTTAVDTSIPVTTS----------TEASSSPTTAEVTSMPTSTPSETSTPLTS 2814
Score = 46.6 bits (109), Expect = 2e-04
Identities = 188/907 (20%), Positives = 294/907 (32%), Gaps = 116/907 (12%)
Query: 132 TEILDNADSENLSPFDSIPDSELLVSPREGSSLHKLLTLSRTPPERDLITPVDPLG---- 187
T I + SE ++P S+P S V+ E S L S TP P
Sbjct: 3210 TSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGT 3269
Query: 188 --PSTGSSRGSGVEMSLPDPSWDF--SPPSFLETS----SPKLPSWRPPRSRPRW--GQS 237
P++ S GS S+P + S S L T+ S + ++ S P G S
Sbjct: 3270 SMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQASSSPPIADGTS 3329
Query: 238 PPPQQRSDGEEEEEVASFSGQILAGELDNCVSSIP---DFPMHLACPEEEDKATAAEMAV 294
P S+G SFS + + +S+ P P+ + TA ++
Sbjct: 3330 MPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSI 3389
Query: 295 PAAG-DESISSLSELVRAMHPYCLPNLTHLAS-------LEDELQEQPDDLTLPEGCVVL 346
P + E + L+ + + P + L++ L E T+ EG +
Sbjct: 3390 PTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLP 3449
Query: 347 EIVGQAATAGDDLEIPVVVRQVSPGPRPVLLDDSLETSSALQLLMPTLESETEAAVPKVT 406
+ + +P+ V+ L ++TS+ + PT S T A V +
Sbjct: 3450 TSTTSEGSTPLSI-MPLSTTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMP 3508
Query: 407 LCSEKEGLSLNSEEKLDSACLLKPREVVEPVVPKEPQNPPANAAPGSQRARKGRKKKSKE 466
+ EG S L PV E + P ++
Sbjct: 3509 TSTAGEG----------STPLTNMPVSTTPVASSEAST--LSTTPVDSNTFVTSSSQASS 3556
Query: 467 QPAACVEGYARRLRSSSRGQSTVGTEVTSQVDNLQKQPQEELQKESGPLQGKGKPRAWAR 526
PA ++ R+ + S G S++ T + S E S P + P
Sbjct: 3557 SPAT-LQVTTMRMSTPSEGSSSLTTMLLSST----YVTSSEASTPSTPSVDRSTP----- 3606
Query: 527 AWAAALENSSPKNLE-RSAGQSSPAK-EGPLDLYP--------KLADTIQTNPIPTHLSL 576
+ NS+P E + S+P++ PL + P A T T P+ T +
Sbjct: 3607 VTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPV 3666
Query: 577 VDSAQASPMPVDSVEADPTAVGPVLAGPVPVDPGLVDLAS-TSSELVEPLPAEPVLINPV 635
+ S Q S PV + E + G P+ V TSSE L P
Sbjct: 3667 ITSTQVSSSPV-TPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSE-------GSTLSTPS 3718
Query: 636 LADSAAVDPAVVPISDNLPPVDAVPSGPAPVDLA-LVDPVPNDLTPVDPVLVKSRPTDP- 693
+ S V + IS + S P++++ L + TPV S P+ P
Sbjct: 3719 VVTSTPVTTSTEAISSSATLDSTTMSVSMPMEISTLGTTILVSTTPVTRFPESSTPSIPS 3778
Query: 694 --RRGAVSSALGGSAPQLLVESESLDPPKTIIPE----VKEVVDSLKIESGTSATTHEAR 747
++++A GS+ +E + P T ++ + + S + A+T
Sbjct: 3779 VYTSMSMTTASEGSSSPTTLEGTTTMPMSTTSERSTLLTTVLISPISVMSPSEASTLSTP 3838
Query: 748 P----RPL-------SLSEYRRRRQQRQAETEERSPQ----------PPTGKWPSLPETP 786
P PL S S R + T ERS P + S+ TP
Sbjct: 3839 PGDTSTPLLTSTKAGSFSIPAEVTTIRISITSERSTPLTTLLVSTTLPTSFPGASIASTP 3898
Query: 787 -----------TGLADIPCLVIPPAPAKKTALQRSPETPLEICLVPVGPSPASPSPEPPV 835
T A P IP A ++ TP +P P +S + P
Sbjct: 3899 PLDTSTTFTPSTDTASTP--TIPVATTISVSVITEGSTPGTTIFIPSTPVTSSTADVFPA 3956
Query: 836 SKPVASSPTEQVPSQEMPLLARPSPPVQSVSPAVPTPPSMSAALPFPAGGLGMPPSLPPP 895
+ S+P P + S + T P+M+ A P + PS P
Sbjct: 3957 TTGAVSTPVITSTELNTPSTSSSSTTTSFSTTKEFTTPAMTTAAPLTYVTMSTAPSTPRT 4016
Query: 896 PLQ--PPSLPLSMGPVLPDPFTHYAPLPSWPCYPHVSPSGYPCLPPPPTVPLVSGTPGAY 953
+ S P T P P PS PPT P P
Sbjct: 4017 TSRGCTTSASTLSATSTPHTSTSVTTRPVTPSSESSRPSTITSHTIPPTFP-----PAHS 4071
Query: 954 AVPPTCS 960
+ PPT S
Sbjct: 4072 STPPTTS 4078
Score = 42.7 bits (99), Expect = 0.003
Identities = 212/1045 (20%), Positives = 334/1045 (31%), Gaps = 173/1045 (16%)
Query: 531 ALENSSPKNLERSAGQSSPAKEGPLDLYPKL---ADTIQTNPIPTHLSLVDSAQASPMPV 587
+L NS+P +G S+P PL + + A T+ T P T++ ++ S +AS P
Sbjct: 264 SLSNSAP------SGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEASSSPT 317
Query: 588 DSVEADPTAVGPVLAGPVPVDPGLVDLASTSSELVEPLPAEPVLINPVLADSAAVDPAVV 647
TA G + ST +E PL + P PV A S ++
Sbjct: 318 -------TAEGTSIP------------TSTYTEGSTPLTSTPASTMPV-ATSEMSTLSIT 357
Query: 648 PISDNLPPVDAVPSGPAPVDLALVDPVPNDLT---------PVDPVLVKSRPTDPRRGAV 698
P+ + + P + + L+ PV +LV S
Sbjct: 358 PVDTSTLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEAS----TT 413
Query: 699 SSALGGSAPQLLVESESLDPPKTIIPEVKEVVDSLKIESGTSATTHEARPRPLSLSEYRR 758
S+ S + SE+ P T E + S E T T+ P++ SE
Sbjct: 414 STIPVDSKTFVTTASEASSSPTTA--EDTSIATSTPSEGSTPLTSMPVSTTPVASSEASN 471
Query: 759 RR------QQRQAETEERSPQPPTGKWPSLPETPTGLADIPCLVIPPAPAKKTALQRSPE 812
+ + + E S PPT + S+P + P++ + +P
Sbjct: 472 LSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTS--------------TPSEGS----TPL 513
Query: 813 TPLEICLVPVGPSPASPSPEPPV--SKPVASSPTEQVPSQEMPLLARP-SPPVQSVSPAV 869
T + + +PV S AS PV S PV +S S + P S P + +P
Sbjct: 514 TSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLT 573
Query: 870 PTPPSMSAALPFPAGGLGMPP-------------SLPPPPLQPPSLPLSMGPVLPDPFTH 916
P S + A P S + S+P S T
Sbjct: 574 NMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITS 633
Query: 917 YAPLPSWPCYPHVSPSGYPCLPPPPTVPLVSGTPGAYAVPPTCSVPWAPPPA-PVSPYSS 975
+ + S T P+ S TP + T S A + P S Y+
Sbjct: 634 MSVSTTLVASSEASTLS--------TTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTE 685
Query: 976 TCT----------------YGPLGWGPGPQHAPFWSTVPPPPLPPASIGRAVPQPKMESR 1019
T L P P ++ P + G ++P
Sbjct: 686 GSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEG 745
Query: 1020 GTPAGP---PENVLPLSMAPPLS---LGLPGHGAPQTE----PTKVEVKPVPASPHPKHK 1069
TP + +L S A LS L H TE PT E +P S +
Sbjct: 746 STPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPIS--TPSE 803
Query: 1070 VSALVQSPQMKALACVSAEGVTVEEPASERLKPETQETRPREKPPLPATKAVPTPRQSTV 1129
S L+ S + S E T+ + P T T + PTP + T
Sbjct: 804 GSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTE---------VSSSPTPAEGTS 854
Query: 1130 PKLPAVHPARLRKLSFLPTPRTQGSEDVVQAFISEIGIEASDLSSLLEQFEKSEAKKECP 1189
R L+ +P T + + +S ++ S + + S E
Sbjct: 855 MPTSTYSEGR-TPLTSMPVSTTLVATSAIST-LSTTPVDTSTPVTNSTEARSSPTTSE-G 911
Query: 1190 PPAPADSLAVGNSGGVDIPQEKRPLDRLQAPELA--NVAGLTPPATPPHQLWKPLAAVSL 1247
P + G++ +P P+ +A L+ V TP T P A
Sbjct: 912 TSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEG- 970
Query: 1248 LAKAKSPKSTAQEGTLKPEGVTEAKHPAAVRLQEGVHGPSRVHVGSGDHDYCVRSRTPP- 1306
P ST EGT P T H + + V + S PP
Sbjct: 971 ---TSIPTSTPSEGT-TPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPT 1026
Query: 1307 ---KKMPALVIPEVGSRWNVKRHQDITIKPVLSLGPAAPPPPCIAASREPLDHRTSSEQA 1363
MP P GS +T PV + + AS E S+ A
Sbjct: 1027 AEGTSMPTST-PSEGS-------TPLTRMPVST---------TMVASSE--TSTLSTTPA 1067
Query: 1364 DPSAPCLAPSSLLSPEASPCRNDMNTRTPPEPSAKQRSMRCYRKACRSASPSSQGWQGRR 1423
D S P S S + M T T E S S+ + S+ S+
Sbjct: 1068 DTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEAST------- 1120
Query: 1424 GRNSRSVSSGSNRTSEASSSSSSSSSSSRSRSRSLSPPHKRWRRSSCSSSGRSRRCSSSS 1483
++ V + T+ S+ +SSS +++ S SPP + + + SS +
Sbjct: 1121 -LSTTPVDTSIPVTT--STEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEA 1177
Query: 1484 SSSSSSSSSSSSSSSSRSRSRSPSP 1508
++ S++ S + ++ + + SP P
Sbjct: 1178 NTLSTTPVDSKTQVATSTEASSPPP 1202
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 89.7 bits (221), Expect = 2e-17
Identities = 174/738 (23%), Positives = 262/738 (35%), Gaps = 139/738 (18%)
Query: 443 QNPPANAAPGSQRARKGRKKKSKEQPAACVEGYARRLRSSSRGQSTVGTEVTSQVDNL-- 500
+N P+ A+ S ++ KKS ++ E + L+S+ R + V ++ T + D
Sbjct: 57 RNSPSAASTSSNDSKAETVKKSAKKVK---EEASSPLKSNKRQREKVASD-TEEADRTSS 112
Query: 501 QKQPQEELQKESGPLQGKGKPRAWARAWAAALENSS-PKNLERSAGQSSPAKEGPLDLYP 559
+K +E+ + + P +G+G+ + + + E SS PK++++ +SP+ P D
Sbjct: 113 KKTKTQEISRPNSPSEGEGES---SDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQD--- 166
Query: 560 KLADTIQTNPIPTHLSLVDSAQASPMPVDSVEADPTAVGPVLAGPVPVDPGLVDLASTSS 619
+ S DS+ M ++A P P L P V P A +S+
Sbjct: 167 -------------NESDSDSSAQQQM----LQAQP----PALQAPTGVTP-----APSSA 200
Query: 620 ELVEPLPAEPVLINPVLADSA-AVDPAVVPISDNLPPVDAVPSGPAPVDLALVDPVPNDL 678
P P L P SA AV P P + P P+ P P P +
Sbjct: 201 P-----PGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQ 255
Query: 679 TPVDPVLVKSRPTDPRRGAVSSALGGSAPQLLVESESLDPPKTIIPEVKEVVDSLKIESG 738
P P P P L GSA Q S + P P +++G
Sbjct: 256 RPPSP----HPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPH-----SLQAG 306
Query: 739 TSATTHEARPRPLSLSEYRRRRQQRQAETEERSPQPPTGKWPSLPETPTGLADIPCLVIP 798
H P+P L + Q P G P+ T L
Sbjct: 307 P-LLQHPGPPQPFGLPP------------QASQGQAPLGTSPAAAYPHTSLQ-------- 345
Query: 799 PAPAKKTALQ------RSPETPLEICLVPVGPSPASPSPEPPVSKPVASSPTEQVPSQEM 852
PA ++ALQ P P + + + P P +P P+ P + +
Sbjct: 346 -LPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQ----------AHKHP 394
Query: 853 PLLARPSPPVQSVSPAVPTPPSMSAALPFPAGGLGMPPSLPPPPLQ--PPSLPLSMGPVL 910
P L+ PSP S++ +P PP++ P + PPS PPPLQ P S PL P
Sbjct: 395 PHLSGPSP--FSMNANLPPPPALK---PLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQ 449
Query: 911 PDPFTHYAPLPSWPCYPHVSPSGYPCLPPPPTV--PLVSGTPGAYAVPPTCSVPWAPPPA 968
P T LP P H + P PP P V G P PPTC PP
Sbjct: 450 PPGLTQSQNLPPPPA-SHPPTGLHQVAPQPPFAQHPFVPGGPPP-ITPPTCPSTSTPPAG 507
Query: 969 PVSPYSSTCTYGPLGWGPGPQHAPFWSTVPPPPLPPASIGRAVPQPKMESRGTPAGPPEN 1028
P + C+ G S+ P P + + + ++ P PP
Sbjct: 508 PGTSAQPPCSGAAASGG----SIAGGSSCPLPTV-------QIKEEALDDAEEPESPPPP 556
Query: 1029 VLPLSMAP-PLSLGLPGH-------------GAPQTEPTKVEVKPVPASPHPKHKVSALV 1074
P S +P P + P H G T + P+ S K + A+
Sbjct: 557 --PRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEAIE 614
Query: 1075 QSPQMKALACVSAEGVTVEEPASERLK-PETQETRPREKPPLPATKAVPTPRQSTVPKLP 1133
++ + AE EE E+ K E + R RE+ A KA + + +
Sbjct: 615 KAKR-------EAEQKAREEREREKEKEKEREREREREREAERAAKASSSAHEGRLSDPQ 667
Query: 1134 AVHPARLRKLSFLPTPRT 1151
P +R SF P P T
Sbjct: 668 LSGPGHMRP-SFEPPPTT 684
Score = 42.4 bits (98), Expect = 0.004
Identities = 131/566 (23%), Positives = 201/566 (35%), Gaps = 100/566 (17%)
Query: 430 PREVVEPVVPKEPQNPPANAAPGSQRARKGRKKKSKEQPAACVEGYARRLRSSSRGQSTV 489
P ++ PQ PP+ P S P + G A + + S Q +
Sbjct: 242 PHTHIQQAPALHPQRPPSPHPP---------PHPSPHPPLQPLTGSAGQPSAPSHAQPPL 292
Query: 490 GTEVTSQVDNLQKQPQEELQKESGPLQGKGKPRAWARAWAAALENSSPK------NLERS 543
+ +LQ P L + GP Q G P ++ A +SP +L+
Sbjct: 293 HGQGPPGPHSLQAGP---LLQHPGPPQPFGLPPQASQGQAPL--GTSPAAAYPHTSLQLP 347
Query: 544 AGQSS-----PAKEGPLDLYPKLADTIQTNPIPTHLSLVDSAQASPMPVDSVEADPTAVG 598
A QS+ P +E PL P I+ P T + + + QA P P ++
Sbjct: 348 ASQSALQSQQPPREQPLPPAPLAMPHIKPPPT-TPIPQLPAPQAHKHPPHLSGPSPFSMN 406
Query: 599 PVLAGPVPVDPGLVDLASTSSELVEPLPAEPVLINPVLADSAAVDPAVVPISDNLPPVDA 658
L P + P L L++ P P + + + L S A P + S NLPP
Sbjct: 407 ANLPPPPALKP-LSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQ-SQNLPPP-- 462
Query: 659 VPSGPAPVDLALVDPVP----NDLTPVDPVLVKSRPTDPRRGAVSSALGGSAPQLLVESE 714
P+ P L V P P + P P + + PT P + G SA
Sbjct: 463 -PASHPPTGLHQVAPQPPFAQHPFVPGGPPPI-TPPTCPSTSTPPAGPGTSA-------- 512
Query: 715 SLDPPKTIIPEVKEVVDSLKIESGTSATTHEARPRPLSLSEYRRRRQQRQAETEERSPQP 774
PP S SG S + P P + +++ + EE P
Sbjct: 513 --QPPC-----------SGAAASGGSIAGGSSCPLPTV-----QIKEEALDDAEEPESPP 554
Query: 775 PTGKWPSLPETPTGLADIPCLVIPPAPAKKTA-----LQRSPET--PLEICLVPVGPSPA 827
P + PS PE P +V P+ A ++A L R + ++ +P+ S
Sbjct: 555 PPPRSPS-PE--------PTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKL 605
Query: 828 SPSPEPPVSKPVASSPT--------EQVPSQEMPLLARPSPPVQSVSPAVPTPPSMSAAL 879
+ E + K + E+ +E + + A + +
Sbjct: 606 AKKREEAIEKAKREAEQKAREEREREKEKEKEREREREREREAERAAKASSSAHEGRLSD 665
Query: 880 PFPAGGLGMPPSLPPPPLQPPSLPLSMGPVLP--DPFTHYAPLPSWPCYPHV-SPS--GY 934
P +G M PS PPP ++P +GP P + YA PHV SP+ +
Sbjct: 666 PQLSGPGHMRPSFEPPPTTIAAVPPYIGPDTPALRTLSEYA-------RPHVMSPTNRNH 718
Query: 935 P-CLPPPPTVPLVS-GTPGAYAVPPT 958
P +P PT PL++ PG Y V PT
Sbjct: 719 PFYMPLNPTDPLLAYHMPGLYNVDPT 744
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 89.7 bits (221), Expect = 2e-17
Identities = 174/738 (23%), Positives = 262/738 (35%), Gaps = 139/738 (18%)
Query: 443 QNPPANAAPGSQRARKGRKKKSKEQPAACVEGYARRLRSSSRGQSTVGTEVTSQVDNL-- 500
+N P+ A+ S ++ KKS ++ E + L+S+ R + V ++ T + D
Sbjct: 611 RNSPSAASTSSNDSKAETVKKSAKKVK---EEASSPLKSNKRQREKVASD-TEEADRTSS 666
Query: 501 QKQPQEELQKESGPLQGKGKPRAWARAWAAALENSS-PKNLERSAGQSSPAKEGPLDLYP 559
+K +E+ + + P +G+G+ + + + E SS PK++++ +SP+ P D
Sbjct: 667 KKTKTQEISRPNSPSEGEGES---SDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQD--- 720
Query: 560 KLADTIQTNPIPTHLSLVDSAQASPMPVDSVEADPTAVGPVLAGPVPVDPGLVDLASTSS 619
+ S DS+ M ++A P P L P V P A +S+
Sbjct: 721 -------------NESDSDSSAQQQM----LQAQP----PALQAPTGVTP-----APSSA 754
Query: 620 ELVEPLPAEPVLINPVLADSA-AVDPAVVPISDNLPPVDAVPSGPAPVDLALVDPVPNDL 678
P P L P SA AV P P + P P+ P P P +
Sbjct: 755 P-----PGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQ 809
Query: 679 TPVDPVLVKSRPTDPRRGAVSSALGGSAPQLLVESESLDPPKTIIPEVKEVVDSLKIESG 738
P P P P L GSA Q S + P P +++G
Sbjct: 810 RPPSP----HPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPH-----SLQAG 860
Query: 739 TSATTHEARPRPLSLSEYRRRRQQRQAETEERSPQPPTGKWPSLPETPTGLADIPCLVIP 798
H P+P L + Q P G P+ T L
Sbjct: 861 P-LLQHPGPPQPFGLPP------------QASQGQAPLGTSPAAAYPHTSLQ-------- 899
Query: 799 PAPAKKTALQ------RSPETPLEICLVPVGPSPASPSPEPPVSKPVASSPTEQVPSQEM 852
PA ++ALQ P P + + + P P +P P+ P + +
Sbjct: 900 -LPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQ----------AHKHP 948
Query: 853 PLLARPSPPVQSVSPAVPTPPSMSAALPFPAGGLGMPPSLPPPPLQ--PPSLPLSMGPVL 910
P L+ PSP S++ +P PP++ P + PPS PPPLQ P S PL P
Sbjct: 949 PHLSGPSP--FSMNANLPPPPALK---PLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQ 1003
Query: 911 PDPFTHYAPLPSWPCYPHVSPSGYPCLPPPPTV--PLVSGTPGAYAVPPTCSVPWAPPPA 968
P T LP P H + P PP P V G P PPTC PP
Sbjct: 1004 PPGLTQSQNLPPPPA-SHPPTGLHQVAPQPPFAQHPFVPGGPPP-ITPPTCPSTSTPPAG 1061
Query: 969 PVSPYSSTCTYGPLGWGPGPQHAPFWSTVPPPPLPPASIGRAVPQPKMESRGTPAGPPEN 1028
P + C+ G S+ P P + + + ++ P PP
Sbjct: 1062 PGTSAQPPCSGAAASGG----SIAGGSSCPLPTV-------QIKEEALDDAEEPESPPPP 1110
Query: 1029 VLPLSMAP-PLSLGLPGH-------------GAPQTEPTKVEVKPVPASPHPKHKVSALV 1074
P S +P P + P H G T + P+ S K + A+
Sbjct: 1111 --PRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEAIE 1168
Query: 1075 QSPQMKALACVSAEGVTVEEPASERLK-PETQETRPREKPPLPATKAVPTPRQSTVPKLP 1133
++ + AE EE E+ K E + R RE+ A KA + + +
Sbjct: 1169 KAKR-------EAEQKAREEREREKEKEKEREREREREREAERAAKASSSAHEGRLSDPQ 1221
Query: 1134 AVHPARLRKLSFLPTPRT 1151
P +R SF P P T
Sbjct: 1222 LSGPGHMRP-SFEPPPTT 1238
Score = 42.4 bits (98), Expect = 0.004
Identities = 131/566 (23%), Positives = 201/566 (35%), Gaps = 100/566 (17%)
Query: 430 PREVVEPVVPKEPQNPPANAAPGSQRARKGRKKKSKEQPAACVEGYARRLRSSSRGQSTV 489
P ++ PQ PP+ P S P + G A + + S Q +
Sbjct: 796 PHTHIQQAPALHPQRPPSPHPP---------PHPSPHPPLQPLTGSAGQPSAPSHAQPPL 846
Query: 490 GTEVTSQVDNLQKQPQEELQKESGPLQGKGKPRAWARAWAAALENSSPK------NLERS 543
+ +LQ P L + GP Q G P ++ A +SP +L+
Sbjct: 847 HGQGPPGPHSLQAGP---LLQHPGPPQPFGLPPQASQGQAPL--GTSPAAAYPHTSLQLP 901
Query: 544 AGQSS-----PAKEGPLDLYPKLADTIQTNPIPTHLSLVDSAQASPMPVDSVEADPTAVG 598
A QS+ P +E PL P I+ P T + + + QA P P ++
Sbjct: 902 ASQSALQSQQPPREQPLPPAPLAMPHIKPPPT-TPIPQLPAPQAHKHPPHLSGPSPFSMN 960
Query: 599 PVLAGPVPVDPGLVDLASTSSELVEPLPAEPVLINPVLADSAAVDPAVVPISDNLPPVDA 658
L P + P L L++ P P + + + L S A P + S NLPP
Sbjct: 961 ANLPPPPALKP-LSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQ-SQNLPPP-- 1016
Query: 659 VPSGPAPVDLALVDPVP----NDLTPVDPVLVKSRPTDPRRGAVSSALGGSAPQLLVESE 714
P+ P L V P P + P P + + PT P + G SA
Sbjct: 1017 -PASHPPTGLHQVAPQPPFAQHPFVPGGPPPI-TPPTCPSTSTPPAGPGTSA-------- 1066
Query: 715 SLDPPKTIIPEVKEVVDSLKIESGTSATTHEARPRPLSLSEYRRRRQQRQAETEERSPQP 774
PP S SG S + P P + +++ + EE P
Sbjct: 1067 --QPPC-----------SGAAASGGSIAGGSSCPLPTV-----QIKEEALDDAEEPESPP 1108
Query: 775 PTGKWPSLPETPTGLADIPCLVIPPAPAKKTA-----LQRSPET--PLEICLVPVGPSPA 827
P + PS PE P +V P+ A ++A L R + ++ +P+ S
Sbjct: 1109 PPPRSPS-PE--------PTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKL 1159
Query: 828 SPSPEPPVSKPVASSPT--------EQVPSQEMPLLARPSPPVQSVSPAVPTPPSMSAAL 879
+ E + K + E+ +E + + A + +
Sbjct: 1160 AKKREEAIEKAKREAEQKAREEREREKEKEKEREREREREREAERAAKASSSAHEGRLSD 1219
Query: 880 PFPAGGLGMPPSLPPPPLQPPSLPLSMGPVLP--DPFTHYAPLPSWPCYPHV-SPS--GY 934
P +G M PS PPP ++P +GP P + YA PHV SP+ +
Sbjct: 1220 PQLSGPGHMRPSFEPPPTTIAAVPPYIGPDTPALRTLSEYA-------RPHVMSPTNRNH 1272
Query: 935 P-CLPPPPTVPLVS-GTPGAYAVPPT 958
P +P PT PL++ PG Y V PT
Sbjct: 1273 PFYMPLNPTDPLLAYHMPGLYNVDPT 1298
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 89.7 bits (221), Expect = 2e-17
Identities = 174/738 (23%), Positives = 262/738 (35%), Gaps = 139/738 (18%)
Query: 443 QNPPANAAPGSQRARKGRKKKSKEQPAACVEGYARRLRSSSRGQSTVGTEVTSQVDNL-- 500
+N P+ A+ S ++ KKS ++ E + L+S+ R + V ++ T + D
Sbjct: 611 RNSPSAASTSSNDSKAETVKKSAKKVK---EEASSPLKSNKRQREKVASD-TEEADRTSS 666
Query: 501 QKQPQEELQKESGPLQGKGKPRAWARAWAAALENSS-PKNLERSAGQSSPAKEGPLDLYP 559
+K +E+ + + P +G+G+ + + + E SS PK++++ +SP+ P D
Sbjct: 667 KKTKTQEISRPNSPSEGEGES---SDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQD--- 720
Query: 560 KLADTIQTNPIPTHLSLVDSAQASPMPVDSVEADPTAVGPVLAGPVPVDPGLVDLASTSS 619
+ S DS+ M ++A P P L P V P A +S+
Sbjct: 721 -------------NESDSDSSAQQQM----LQAQP----PALQAPTGVTP-----APSSA 754
Query: 620 ELVEPLPAEPVLINPVLADSA-AVDPAVVPISDNLPPVDAVPSGPAPVDLALVDPVPNDL 678
P P L P SA AV P P + P P+ P P P +
Sbjct: 755 P-----PGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQ 809
Query: 679 TPVDPVLVKSRPTDPRRGAVSSALGGSAPQLLVESESLDPPKTIIPEVKEVVDSLKIESG 738
P P P P L GSA Q S + P P +++G
Sbjct: 810 RPPSP----HPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPH-----SLQAG 860
Query: 739 TSATTHEARPRPLSLSEYRRRRQQRQAETEERSPQPPTGKWPSLPETPTGLADIPCLVIP 798
H P+P L + Q P G P+ T L
Sbjct: 861 P-LLQHPGPPQPFGLPP------------QASQGQAPLGTSPAAAYPHTSLQ-------- 899
Query: 799 PAPAKKTALQ------RSPETPLEICLVPVGPSPASPSPEPPVSKPVASSPTEQVPSQEM 852
PA ++ALQ P P + + + P P +P P+ P + +
Sbjct: 900 -LPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQ----------AHKHP 948
Query: 853 PLLARPSPPVQSVSPAVPTPPSMSAALPFPAGGLGMPPSLPPPPLQ--PPSLPLSMGPVL 910
P L+ PSP S++ +P PP++ P + PPS PPPLQ P S PL P
Sbjct: 949 PHLSGPSP--FSMNANLPPPPALK---PLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQ 1003
Query: 911 PDPFTHYAPLPSWPCYPHVSPSGYPCLPPPPTV--PLVSGTPGAYAVPPTCSVPWAPPPA 968
P T LP P H + P PP P V G P PPTC PP
Sbjct: 1004 PPGLTQSQNLPPPPA-SHPPTGLHQVAPQPPFAQHPFVPGGPPP-ITPPTCPSTSTPPAG 1061
Query: 969 PVSPYSSTCTYGPLGWGPGPQHAPFWSTVPPPPLPPASIGRAVPQPKMESRGTPAGPPEN 1028
P + C+ G S+ P P + + + ++ P PP
Sbjct: 1062 PGTSAQPPCSGAAASGG----SIAGGSSCPLPTV-------QIKEEALDDAEEPESPPPP 1110
Query: 1029 VLPLSMAP-PLSLGLPGH-------------GAPQTEPTKVEVKPVPASPHPKHKVSALV 1074
P S +P P + P H G T + P+ S K + A+
Sbjct: 1111 --PRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEAIE 1168
Query: 1075 QSPQMKALACVSAEGVTVEEPASERLK-PETQETRPREKPPLPATKAVPTPRQSTVPKLP 1133
++ + AE EE E+ K E + R RE+ A KA + + +
Sbjct: 1169 KAKR-------EAEQKAREEREREKEKEKEREREREREREAERAAKASSSAHEGRLSDPQ 1221
Query: 1134 AVHPARLRKLSFLPTPRT 1151
P +R SF P P T
Sbjct: 1222 LSGPGHMRP-SFEPPPTT 1238
Score = 42.4 bits (98), Expect = 0.004
Identities = 131/566 (23%), Positives = 201/566 (35%), Gaps = 100/566 (17%)
Query: 430 PREVVEPVVPKEPQNPPANAAPGSQRARKGRKKKSKEQPAACVEGYARRLRSSSRGQSTV 489
P ++ PQ PP+ P S P + G A + + S Q +
Sbjct: 796 PHTHIQQAPALHPQRPPSPHPP---------PHPSPHPPLQPLTGSAGQPSAPSHAQPPL 846
Query: 490 GTEVTSQVDNLQKQPQEELQKESGPLQGKGKPRAWARAWAAALENSSPK------NLERS 543
+ +LQ P L + GP Q G P ++ A +SP +L+
Sbjct: 847 HGQGPPGPHSLQAGP---LLQHPGPPQPFGLPPQASQGQAPL--GTSPAAAYPHTSLQLP 901
Query: 544 AGQSS-----PAKEGPLDLYPKLADTIQTNPIPTHLSLVDSAQASPMPVDSVEADPTAVG 598
A QS+ P +E PL P I+ P T + + + QA P P ++
Sbjct: 902 ASQSALQSQQPPREQPLPPAPLAMPHIKPPPT-TPIPQLPAPQAHKHPPHLSGPSPFSMN 960
Query: 599 PVLAGPVPVDPGLVDLASTSSELVEPLPAEPVLINPVLADSAAVDPAVVPISDNLPPVDA 658
L P + P L L++ P P + + + L S A P + S NLPP
Sbjct: 961 ANLPPPPALKP-LSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQ-SQNLPPP-- 1016
Query: 659 VPSGPAPVDLALVDPVP----NDLTPVDPVLVKSRPTDPRRGAVSSALGGSAPQLLVESE 714
P+ P L V P P + P P + + PT P + G SA
Sbjct: 1017 -PASHPPTGLHQVAPQPPFAQHPFVPGGPPPI-TPPTCPSTSTPPAGPGTSA-------- 1066
Query: 715 SLDPPKTIIPEVKEVVDSLKIESGTSATTHEARPRPLSLSEYRRRRQQRQAETEERSPQP 774
PP S SG S + P P + +++ + EE P
Sbjct: 1067 --QPPC-----------SGAAASGGSIAGGSSCPLPTV-----QIKEEALDDAEEPESPP 1108
Query: 775 PTGKWPSLPETPTGLADIPCLVIPPAPAKKTA-----LQRSPET--PLEICLVPVGPSPA 827
P + PS PE P +V P+ A ++A L R + ++ +P+ S
Sbjct: 1109 PPPRSPS-PE--------PTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKL 1159
Query: 828 SPSPEPPVSKPVASSPT--------EQVPSQEMPLLARPSPPVQSVSPAVPTPPSMSAAL 879
+ E + K + E+ +E + + A + +
Sbjct: 1160 AKKREEAIEKAKREAEQKAREEREREKEKEKEREREREREREAERAAKASSSAHEGRLSD 1219
Query: 880 PFPAGGLGMPPSLPPPPLQPPSLPLSMGPVLP--DPFTHYAPLPSWPCYPHV-SPS--GY 934
P +G M PS PPP ++P +GP P + YA PHV SP+ +
Sbjct: 1220 PQLSGPGHMRPSFEPPPTTIAAVPPYIGPDTPALRTLSEYA-------RPHVMSPTNRNH 1272
Query: 935 P-CLPPPPTVPLVS-GTPGAYAVPPT 958
P +P PT PL++ PG Y V PT
Sbjct: 1273 PFYMPLNPTDPLLAYHMPGLYNVDPT 1298
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 89.0 bits (219), Expect = 4e-17
Identities = 226/921 (24%), Positives = 320/921 (34%), Gaps = 190/921 (20%)
Query: 569 PIPTHLSLVDSAQASPMPVDS-----VEADPTA-VGPVLAGPVP-------VDPGLVDLA 615
P P + + + P+P V +P A +GPV P P PG V
Sbjct: 985 PRPKPVKMKVNRMLQPVPKQEGRTVVVVNNPRAPLGPVPVRPPPGPELSAQPTPGPVPQV 1044
Query: 616 STSSELVEPLPAEPVLINPVLADSAAVDPAVVPISDNLPPVDAVPSG------------- 662
+S +V PA P LI + P + P S +LP V P G
Sbjct: 1045 LPASLMVSASPAGPPLIPASRPPGPVLLPPLQPNSGSLPQVLPSPLGVLSGTSRPPTPTL 1104
Query: 663 ------PAPVDLALVDPVPNDLTPVDPVLVKSRPTDPRRGA-VSSALGGSAPQLLVESES 715
PAPV L+ P P + + P+ V T P A +S +A V + +
Sbjct: 1105 SLKPTPPAPVRLSPAPP-PGSSSLLKPLTVPPGYTFPPAAATTTSTTTATATTTAVPAPT 1163
Query: 716 LDPPKTII-PEVKEVVDSLKIES--------------------------GTSATTHEARP 748
P + I+ P+++ + S ++ S G T A+
Sbjct: 1164 PAPQRLILSPDMQARLPSGEVVSIGQLASLAQRPVANAGGSKPLTFQIQGNKLTLTGAQV 1223
Query: 749 RPLSLSEYRRRRQQ----------------------RQAETEERSPQPPT---GKWPSLP 783
R L++ + R ++ QA P P + PS
Sbjct: 1224 RQLAVGQPRPLQRNVVHLVSAGGQHHLISQPAHVALIQAVAPTPGPTPVSVLPSSTPSTT 1283
Query: 784 ETPTGLA------DIPCLVIPPAPAKKTALQRSPETPLEICLVPVGPSPASPS------- 830
PTGL+ +P ++ K ++++P L + P+ P+P PS
Sbjct: 1284 PAPTGLSLPLAANQVPPTMVNNTGVVKIVVRQAPRDGL-TPVPPLAPAPRPPSSGLPAVL 1342
Query: 831 -----------PEPPVSKPVASSPTEQVPSQEMPLLARPSPPVQSVSPAVPTPPSMSAAL 879
P P + A PT + + L+ PSP V + +P P ++S+ L
Sbjct: 1343 NPRPTLTPGRLPTPTLGTARAPMPTPTLVRPLLKLVHSPSPEVSASAPGA-APLTISSPL 1401
Query: 880 PFPAGGLGMPPSLPPP-----PLQPP-----------SLPLSMGPVLPDPFTHYAPLP-S 922
P+ L P S P P PL P SLP+S+ LP P + +P S
Sbjct: 1402 HVPS-SLPGPASSPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIPIS 1460
Query: 923 WPCYPHVSPSGYPCLPPPPTVPLVSGTPGAYAVPPTCSVPWAPP----PAPVSPYSSTCT 978
P S PP P+V PG ++ P+ + P A A SS+ T
Sbjct: 1461 APLTVSASGPALLTSVTPPLAPVVPAAPGPPSLAPSGASPSASALTLGLATAPSLSSSQT 1520
Query: 979 YG-PLGWGPGPQHAP-FWSTVPP---PPLPPASIGRAVPQPKMESRGTPAGPPENVLPLS 1033
G PL P H P STV P P L PAS A P P P P L+
Sbjct: 1521 PGHPLLLAPTSSHVPGLNSTVAPACSPVLVPAS-ALASPFP-----SAPNPAPAQASLLA 1574
Query: 1034 MAPPLSLGLPGHGAPQTEPTKVEVKPVPASPHPKHKVSALVQSPQMKALACVSAEGVTVE 1093
A S L AP P + P PA P + L SP + S V V
Sbjct: 1575 PASSASQALATPLAPMAAPQTAILAPSPAP--PLAPLPVLAPSPGAAPVLASSQTPVPVM 1632
Query: 1094 EPASERLKPETQETRPREKPPLPATKAVPTPRQSTVPKLPAVHPARLRKLSFLPTPRTQG 1153
P+S T T P+PA V P ST LPA P S LP+P +
Sbjct: 1633 APSS------TPGTSLASASPVPAPTPVLAP-SSTQTMLPAPVP------SPLPSPASTQ 1679
Query: 1154 SEDVVQAFISEIGIEASDLSSLL-----------EQFEKSEAKKECPPPAPADSLAVGNS 1202
+ + A +G + + L + + A P PA SLA G
Sbjct: 1680 TLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASSLVPTPAQTLSLAPGPP 1739
Query: 1203 GGVDIPQEKRPLDRLQAPELANVAGLTPPATPPHQLWKPLAAVSLLAKAKSPKSTAQEGT 1262
G + L AP LA + + P P H L LA S A +P S Q T
Sbjct: 1740 LG-----PTQTLSLAPAPPLAPASPVGP--APAHTL--TLAPASSSASLLAPAS-VQTLT 1789
Query: 1263 LKPEGVTEAKHPAAVRLQEGVHGPSRVHVGSGDHDYCVRSRTPPKKMPALVIPEVGSRWN 1322
L P V AA L P+ + V S + +P ++ SR
Sbjct: 1790 LSPAPVPTLGPAAAQTL---ALAPASTQSPASQASSLVVSASGAAPLPVTMV----SRLP 1842
Query: 1323 VKRHQDITIKPVLSLGPAAPP 1343
V + + T+ L GP +PP
Sbjct: 1843 VSKDEPDTL--TLRSGPPSPP 1861
Score = 81.6 bits (200), Expect = 6e-15
Identities = 218/938 (23%), Positives = 323/938 (34%), Gaps = 171/938 (18%)
Query: 362 PVVVRQVSPGPRPVLLDDSL--ETSSALQLLMPTLESETEAAVPKVTLCSEKEGLSLNSE 419
P + Q +PGP P +L SL S A L+P +P + S L S
Sbjct: 1030 PELSAQPTPGPVPQVLPASLMVSASPAGPPLIPASRPPGPVLLPPLQPNSGSLPQVLPSP 1089
Query: 420 EKLDSACLLKPREV--VEPVVPKEPQNPPANAAPGSQRARKGRKKKSKEQPAACVEGYAR 477
+ S P ++P P + PA PGS K P GY
Sbjct: 1090 LGVLSGTSRPPTPTLSLKPTPPAPVRLSPA-PPPGSSSLLK---------PLTVPPGYTF 1139
Query: 478 RLRSSSRGQSTVGTEVTSQVDNLQKQPQEELQKESGPLQGKGKPRAWARAWAAALENSSP 537
+++ +T T T+ V PQ + P AR P
Sbjct: 1140 PPAAATTTSTTTATATTTAVPAPTPAPQRLIL----------SPDMQARL---------P 1180
Query: 538 KNLERSAGQSSPAKEGPLDLYPKLADTIQTNPIPTHLSLVDSAQASPMPVDSVEADPTAV 597
S GQ + + P +A+ + P+ + Q + + + + AV
Sbjct: 1181 SGEVVSIGQLASLAQRP------VANAGGSKPLTFQI------QGNKLTLTGAQVRQLAV 1228
Query: 598 GPVLAGPVPVDPGLVDLASTSSELVEPLPAEPVLINPVLADSAAVDPAVVPISDNLPPVD 657
G P P+ +V L S + L ++P + L + A P P+S + P
Sbjct: 1229 GQ----PRPLQRNVVHLVSAGGQ--HHLISQPAHV--ALIQAVAPTPGPTPVS--VLPSS 1278
Query: 658 AVPSGPAPVDLAL------VDPVPNDLTPVDPVLVKSRPTDPRRGAVSSALGGSAPQLLV 711
+ PAP L+L V P + T V ++V+ P D G AP+
Sbjct: 1279 TPSTTPAPTGLSLPLAANQVPPTMVNNTGVVKIVVRQAPRD---GLTPVPPLAPAPR--- 1332
Query: 712 ESESLDPPKTIIPEVKEVVDSL---KIESGTSATTHEARPRPLSLSEYRRRRQQRQAETE 768
PP + +P V +L ++ + T T P P + + E
Sbjct: 1333 ------PPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRPLLKLVHSPSPEVS 1386
Query: 769 ERSP--QPPTGKWP-SLPETPTGLADIPCLVIPPAPAKKTALQRSPETPLEICL---VPV 822
+P P T P +P + G A P + IP + + + + PL L VP
Sbjct: 1387 ASAPGAAPLTISSPLHVPSSLPGPASSP-MPIPNSSPLASPVSSTVSVPLSSSLPISVPT 1445
Query: 823 G-PSPASPSPEPPVSKPVASSPTEQVPSQEMPLLARPSPPVQSVSPAVPTPPSMSAALPF 881
P+PAS P+S P+ V + LL +PP+ V PA P PPS++ +
Sbjct: 1446 TLPAPASAPLTIPISAPLT------VSASGPALLTSVTPPLAPVVPAAPGPPSLAPSGAS 1499
Query: 882 PAG-----GLGMPPSLPPPPLQPPSLPLSMGPV---LPDPFTHYAPLPSWPCYPHVSPSG 933
P+ GL PSL Q P PL + P +P + AP C P + P+
Sbjct: 1500 PSASALTLGLATAPSLSSS--QTPGHPLLLAPTSSHVPGLNSTVAP----ACSPVLVPAS 1553
Query: 934 YPCLP----PPPTVPLVSGTPGAYAVPPTCSVPWAPPPAPVSPYSSTCTYGPLGWGPGPQ 989
P P P S A + + P AP AP T P P P
Sbjct: 1554 ALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAP-----QTAILAP---SPAPP 1605
Query: 990 HAPFWSTVPPPPLPPASIGRAVPQPKMESRGTP------AGP---PENVLPLS-----MA 1035
AP P P P P P M TP A P P VL S +
Sbjct: 1606 LAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLP 1665
Query: 1036 PPLSLGLPGHGAPQTEPTKVEVKPVPASPHPKHKVSALVQSPQ----MKALACVSAEGVT 1091
P+ LP + QT + P P +S +PQ + L+ A +
Sbjct: 1666 APVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASSLV 1725
Query: 1092 VEEPASERLKP-----ETQETRPREKPPL-PATKAVPTPRQSTVPKLPA------VHPAR 1139
+ L P TQ PPL PA+ P P T+ PA + PA
Sbjct: 1726 PTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASPVGPAPAH-TLTLAPASSSASLLAPAS 1784
Query: 1140 LRKLSFLPTPRTQGSEDVVQAFISEIGIEASDLSSLLEQFEKSEAKKECPPPAPADSLAV 1199
++ L+ P P + +G A+ +L +S P + A SL V
Sbjct: 1785 VQTLTLSPAP------------VPTLGPAAAQTLALAPASTQS-------PASQASSLVV 1825
Query: 1200 GNSGGVDIP---QEKRPLDRLQAPELANVAGLTPPATP 1234
SG +P + P+ + + L +G PP+ P
Sbjct: 1826 SASGAAPLPVTMVSRLPVSKDEPDTLTLRSG--PPSPP 1861
Score = 77.4 bits (189), Expect = 1e-13
Identities = 132/545 (24%), Positives = 192/545 (35%), Gaps = 67/545 (12%)
Query: 582 ASPMPVDSVEADPTAVGPVLAGPVPVDPGLVDLASTSSELVE-PLPAEPVLINPVLADSA 640
A+P+ + S P+++ + P+P+ P LAS S V PL + + P +
Sbjct: 1392 AAPLTISSPLHVPSSLPGPASSPMPI-PNSSPLASPVSSTVSVPLSSSLPISVPTTLPAP 1450
Query: 641 AVDPAVVPISDNLPPVDAVPSGPAPVDLALVDPVPNDLTPVDPVLVKSRPTDPRRGAVSS 700
A P +PIS P+ SGPA L V P + P P P+ A +
Sbjct: 1451 ASAPLTIPIS---APLTVSASGPAL--LTSVTPPLAPVVPAAPGPPSLAPSGASPSASAL 1505
Query: 701 ALGGSAPQLLVESESLDPPKTIIPEVKEVVDSLKIESGTSATTHEA-----RPRPLSLSE 755
LG + L S++ P + P V G ++T A P S
Sbjct: 1506 TLGLATAPSLSSSQTPGHPLLLAPTSSHV-------PGLNSTVAPACSPVLVPASALASP 1558
Query: 756 YRRRRQQRQAETEERSPQPPTGKWPSLPETPTGLADIPCLVIPPAPAKKTALQRSPETPL 815
+ A+ +P + + P P L PAP P PL
Sbjct: 1559 FPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAP---------PLAPL 1609
Query: 816 EICLVPVGPSPASPSPEPPVSKPVASSPTEQVPSQEMPLLARPSPPVQSVSPAVPTPPSM 875
+ G +P S + PV SS + P+ A P+P + S P +
Sbjct: 1610 PVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPA-PTPVLAPSSTQTMLPAPV 1668
Query: 876 SAALPFPAG--GLGMPPSLPPP-PLQPPSLPLSMGPVLPDPFTHYAPLPSWPCYPHVSPS 932
+ LP PA L + P+L P PS LS+G P P P+ ++P+
Sbjct: 1669 PSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQ-----GPFPTQTL--SLTPA 1721
Query: 933 GYPCLPPPPTVPLVSGTPGAYAVPPTCSVPWAPPPAPVSPYSSTCTYGPLGWGPGPQHAP 992
P T+ L G P T S+ APP AP SP GP P H
Sbjct: 1722 SSLVPTPAQTLSLAPGPP--LGPTQTLSLAPAPPLAPASPV-----------GPAPAHT- 1767
Query: 993 FWSTVPPPPLPPASIGRAVPQPKMESRGTPAGPPENVLPLSMAPPLSLGLPGHGAPQTEP 1052
L PAS ++ P T + P L + A L+L +P ++
Sbjct: 1768 -------LTLAPASSSASLLAPASVQTLTLSPAPVPTLGPAAAQTLALAPASTQSPASQA 1820
Query: 1053 TKVEVKPVPASPHPKHKVSAL-VQSPQMKALACVSAEGVTVEEPASERLKPETQETRPRE 1111
+ + V A+P P VS L V + L S P+ RPR
Sbjct: 1821 SSLVVSASGAAPLPVTMVSRLPVSKDEPDTLTLRSG------PPSPPSTATSFGGPRPRR 1874
Query: 1112 KPPLP 1116
+PP P
Sbjct: 1875 QPPPP 1879
Score = 73.9 bits (180), Expect = 1e-12
Identities = 198/859 (23%), Positives = 301/859 (35%), Gaps = 148/859 (17%)
Query: 584 PMPVDSVEADPTAVGPVLAGPVP--VDPGLVDLASTSSELVEPL--PAEPVLINPVLADS 639
P P + A PT GPVP + L+ AS + + P P PVL+ P+ +S
Sbjct: 1026 PPPGPELSAQPTP------GPVPQVLPASLMVSASPAGPPLIPASRPPGPVLLPPLQPNS 1079
Query: 640 AAVDPAVVPI------SDNLPPVDAV---PSGPAPVDLALVDPVPNDLTPVDPVLVKSRP 690
++ P V+P + PP + P+ PAPV L+ P P + + P+ V
Sbjct: 1080 GSL-PQVLPSPLGVLSGTSRPPTPTLSLKPTPPAPVRLSPAPP-PGSSSLLKPLTVPPGY 1137
Query: 691 TDPRRGAVS-SALGGSAPQLLVESESLDPPKTII-PEVKEVVDSLKIESGTSATTHEARP 748
T P A + S +A V + + P + I+ P+++ + S ++ S + RP
Sbjct: 1138 TFPPAAATTTSTTTATATTTAVPAPTPAPQRLILSPDMQARLPSGEVVSIGQLASLAQRP 1197
Query: 749 -------RPLSLSEYRRRRQQRQAETEERS---PQP---------PTGKWPSLPETPTGL 789
+PL+ + A+ + + P+P G L P +
Sbjct: 1198 VANAGGSKPLTFQIQGNKLTLTGAQVRQLAVGQPRPLQRNVVHLVSAGGQHHLISQPAHV 1257
Query: 790 ADIPCLVIPPAPAKKTALQRSPETPLEICLVPVGPS-PASPSPEPPV---SKPVASSPTE 845
A I + P P + L P + P G S P + + PP + V
Sbjct: 1258 ALIQAVAPTPGPTPVSVL---PSSTPSTTPAPTGLSLPLAANQVPPTMVNNTGVVKIVVR 1314
Query: 846 QVPSQEM----PLLARPSPPVQSVSPAV--PTPPSMSAALPFPAGGLGMPPSLPPPPLQP 899
Q P + PL P PP + PAV P P LP P G P +P P L
Sbjct: 1315 QAPRDGLTPVPPLAPAPRPPSSGL-PAVLNPRPTLTPGRLPTPTLGTARAP-MPTPTLVR 1372
Query: 900 PSLPLSMGPVLPD---------PFTHYAPLPSWPCYPHVSPSGYPCLPPPPTVPLVSGTP 950
P L L P P+ P T +PL P P+ P +P P + PL S
Sbjct: 1373 PLLKLVHSPS-PEVSASAPGAAPLTISSPLHVPSSLP--GPASSP-MPIPNSSPLASPVS 1428
Query: 951 GAYAVPPTCSVPWAPPPAPVSPYSSTCTYGPLGWGPGPQHAPFWSTVPPPPLPPASIGRA 1010
+VP + S+P + P +T+P P P +I
Sbjct: 1429 STVSVPLSSSLPISVP----------------------------TTLPAPASAPLTI--P 1458
Query: 1011 VPQPKMESRGTPAGPPENVLPLSMAPPLSLGLPGHGAPQTEPTKVEVKPVPASPHPKHKV 1070
+ P S PA L S+ PPL+ +P P + + P ASP
Sbjct: 1459 ISAPLTVSASGPA------LLTSVTPPLAPVVPAAPGPPS------LAPSGASPSASALT 1506
Query: 1071 SALVQSPQMKALACVSAEGVTVEEPASERLKPETQETRPREKPPLPATKAVPTPRQSTVP 1130
L +P + + + P S + P P L A+ +P P
Sbjct: 1507 LGLATAPSLSSSQTPGHPLLLA--PTSSHVPGLNSTVAPACSPVLVPASALASP----FP 1560
Query: 1131 KLPAVHPARLRKLSFLPTPRTQGSEDVVQAFISEIGIEASDLSSLLEQFEKSEAKKECPP 1190
P PA+ L+ P + S QA + + A+ +++L A PP
Sbjct: 1561 SAPNPAPAQASLLA----PASSAS----QALATPLAPMAAPQTAIL-------APSPAPP 1605
Query: 1191 PAPADSLAVGNSGGVDIPQEKRPLDRLQAPELA---NVAGLTPPATPPHQLWKPLAAVSL 1247
AP LA + + P+ + AP ++A +P P L L
Sbjct: 1606 LAPLPVLAPSPGAAPVLASSQTPVP-VMAPSSTPGTSLASASPVPAPTPVLAPSSTQTML 1664
Query: 1248 LAKAKSP-KSTAQEGTLKPEGVTEAKHPAAVRLQEGVHGPSRVHVGSGDHDYCVRSRTPP 1306
A SP S A TL A PA G + +G+G+ ++T
Sbjct: 1665 PAPVPSPLPSPASTQTL-------ALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLS 1717
Query: 1307 KKMPALVIPEVGSRWNVKRHQDITIKPVLSLGPA---APPPPCIAASREPLDHRTSSEQA 1363
+ ++P ++ + LSL PA AP P A L +S A
Sbjct: 1718 LTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASPVGPAPAHTLTLAPASSSA 1777
Query: 1364 DPSAPCLAPSSLLSPEASP 1382
AP + LSP P
Sbjct: 1778 SLLAPASVQTLTLSPAPVP 1796
Score = 71.2 bits (173), Expect = 8e-12
Identities = 118/475 (24%), Positives = 164/475 (34%), Gaps = 50/475 (10%)
Query: 579 SAQASPMPV--DSVEADPTAVGPVLAGPVPVDPGLVDLASTSSELVEPLPAEPVLINPVL 636
SA ASP P + A + + P + + L +A+ + ++ P PA P+ PVL
Sbjct: 1553 SALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAPPLAPLPVL 1612
Query: 637 ADSAAVDPAVVPISDNLPPVDAVPSGPAPVDLALVDPVPNDLTPVDPVLVKSRPTDPRRG 696
A S P + S P PS LA PVP PVL S
Sbjct: 1613 APSPGAAPVLA--SSQTPVPVMAPSSTPGTSLASASPVPAPT----PVLAPSSTQTMLPA 1666
Query: 697 AVSSALGGSAPQLLVESESLDPPKTIIPEVKEVVDSLKIESGTSATTHEARPRPLSLSEY 756
V S L A +++L + P + S + GT + LSL+
Sbjct: 1667 PVPSPLPSPA-----STQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTP- 1720
Query: 757 RRRRQQRQAETEERSPQPPTGKWPSLPETPTGLADIPCLVIPPAPAKKTALQRSPETPLE 816
A+T +P PP G +L P P + PAPA L +P +
Sbjct: 1721 ASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAPPL-APASPVGPAPAHTLTL--APASSSA 1777
Query: 817 ICLVPVGPSPASPSPEP-PVSKPVASSPTEQVPSQEMPLLARPSPPVQSVSPAVPTPPSM 875
L P + SP P P P A+ P+ ++ S V S S A P P +M
Sbjct: 1778 SLLAPASVQTLTLSPAPVPTLGPAAAQTLALAPASTQSPASQASSLVVSASGAAPLPVTM 1837
Query: 876 SAALPFPAGGLGMPPSLPPPPLQPPSLPLSMGPVLPDPFTHYAPLPSWPCYPHVSPSGYP 935
+ LP PP PPS S G P P P P P Y
Sbjct: 1838 VSRLPVSKDEPDTLTLRSGPP-SPPSTATSFGG--PRPRRQPPPPPRSPFYLDSLEEKRK 1894
Query: 936 CLPPPPTVPLVSGTPGAYAVPPT--------CSVPWAPPPAPVSPYSSTCTYGPLGWGPG 987
+ + A+ P C++P P +P+ P S PG
Sbjct: 1895 RQRSERLERIFQLSEAHGALAPVYGTEVLDFCTLP-QPVASPIGPRS-----------PG 1942
Query: 988 PQHAPFWSTVPPPPLPPASIGRAV--PQPKMESRGTPAGPPENVLPLSMAPPLSL 1040
P H FW+ + RAV PQ +++ V+P APP SL
Sbjct: 1943 PSHPTFWTYT-------EAAHRAVLFPQQRLDQLSEIIERFIFVMPPVEAPPPSL 1990
Score = 66.6 bits (161), Expect = 2e-10
Identities = 127/520 (24%), Positives = 188/520 (36%), Gaps = 98/520 (18%)
Query: 535 SSPKNLERSAGQSSPAKEG-PLDLYPKLADTIQTN-PIPTHLSLVDSAQASPMPVDSVEA 592
SSP + S+ +SP + L L ++ T P P L A S A
Sbjct: 1412 SSPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPA 1471
Query: 593 DPTAVGPVLAGPVPVDPG----------------LVDLASTSSELVEPLPAEPVLINPVL 636
T+V P LA VP PG + LA+ S P P+L+ P
Sbjct: 1472 LLTSVTPPLAPVVPAAPGPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTS 1531
Query: 637 AD--------SAAVDPAVVPISDNLPPVDAVPSGPAPVDLALVDPVPND----LTPVDPV 684
+ + A P +VP S P + P+ PAP +L+ P + TP+ P+
Sbjct: 1532 SHVPGLNSTVAPACSPVLVPASALASPFPSAPN-PAPAQASLLAPASSASQALATPLAPM 1590
Query: 685 ------LVKSRPTDPRRGAVSSALGGSAPQLLVESESLDPPKTIIPEVKEVVDSLKIESG 738
++ P P A A +L S++ P V + G
Sbjct: 1591 AAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVP-----------VMAPSSTPG 1639
Query: 739 TSATTHEARPRPLSLSEYRRRRQQRQAETEERSPQPPTGKW----PSLPETPTGLADIPC 794
TS + P P + + A P P + + P+L T G +
Sbjct: 1640 TSLASASPVPAPTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQT 1699
Query: 795 LVI----PPAPAKKTALQRSPETPLEICLVPVGPSPASPSPEPPVSKPVASSPTEQVPSQ 850
L + P P L +P + LVP S +P PP+ P+Q
Sbjct: 1700 LSLGTGNPQGPFPTQTLSLTPAS----SLVPTPAQTLSLAPGPPLG-----------PTQ 1744
Query: 851 EMPLLARPSPPVQSVSPAVPTPP-SMSAALPFPAGGLGMPPSLPPPPLQPPSLPLSMGPV 909
+ L P+PP+ SP P P +++ A + L P S+ L P +P ++GP
Sbjct: 1745 TLSL--APAPPLAPASPVGPAPAHTLTLAPASSSASLLAPASVQTLTLSPAPVP-TLGPA 1801
Query: 910 LPD-----PFTHYAPLPSWPCYPHVSPSGYPCLPPPPTVPLVSGTPGAYAVPPTCSVPWA 964
P + +P S VS SG LP V +VS P + P T ++
Sbjct: 1802 AAQTLALAPASTQSP-ASQASSLVVSASGAAPLP----VTMVSRLPVSKDEPDTLTLRSG 1856
Query: 965 PPPAPVSPYSSTCTYGPLGWGPGPQHAPFWSTVPPPPLPP 1004
PP SP S+ ++G GP P+ P PPPP P
Sbjct: 1857 PP----SPPSTATSFG----GPRPRRQP-----PPPPRSP 1883
Score = 57.4 bits (137), Expect = 1e-07
Identities = 204/877 (23%), Positives = 288/877 (32%), Gaps = 148/877 (16%)
Query: 738 GTSATTHEARPRPLSLSEYRRRRQQ--RQAETEERSPQPPTGKWPSLPETPTGLADIPCL 795
G A T A P+ + R R + ER P+P P+ P A IP L
Sbjct: 2401 GARAETQGANHTPVISAHQTRSTTTPPRCSPARERVPRPAPRPRPTPASAP---AAIPAL 2457
Query: 796 VIPPAPAKKTALQRSPETPLEICLVPVGPSPASPSPEPPVSKPVASSPTEQVPSQEMPLL 855
V P A + S P+ I V + PSP PS PP S P + P P
Sbjct: 2458 VPVPVSAP---VPISAPNPITILPVHILPSPPPPSQIPPCSSPACTPPPACTPPP----- 2509
Query: 856 ARPSPPVQS--VSPAVPT---PPSMSAALPFPAGGLGMPPSLPPPP-------LQPPSLP 903
A PP Q+ V+P+ P PPS +P A +P L P P SL
Sbjct: 2510 AHTPPPAQTCLVTPSSPLLLGPPS----VPISASVTNLPLGLRPEAELCAQALASPESLE 2565
Query: 904 L-SMGPVLPDPFTHYAPLPSWPCYPHVSPSGYPCLPPPPTVPLVSGTPGAYAVPPTCSVP 962
L S+ + P P + P L P+ P ++ G S+P
Sbjct: 2566 LASVASSETSSLSLVPPKDLLPVAVEILPVSEKNLSLTPSAPSLTLEAG--------SIP 2617
Query: 963 -WAPPPAPVSPYSSTCTYGPLGWGPGPQHAPFW-STVPPPPLPPASIGRAVPQPKMESRG 1020
AP S +T T P G + P S LPP++ Q +E+
Sbjct: 2618 NGQEQEAPDSAEGTTLTVLPEG-----EELPLCVSESNGLELPPSAASDEPLQEPLEADR 2672
Query: 1021 TPAGPPENVLPLSM-APPLSLGLPGHGAPQT--EPTKVEVKPVPASPHPKHKVSALV--- 1074
T E P S P L AP T T P PA P P+ + SA V
Sbjct: 2673 TSEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGPSPARP-PRRRTSADVEIR 2731
Query: 1075 --------QSPQMKALACVSAEGVTVEEP------------ASERLKPETQETRPREKPP 1114
Q P K L + VTV E A+ L P ET P
Sbjct: 2732 GQGTGRPGQPPGPKVLRKLPGRLVTVVEEKELVRRRRQQRGAASTLVPGVSET--SASPG 2789
Query: 1115 LPATKAVPTPRQSTVPKLPAVHPARLRKLSFLPTPRTQG--SEDVVQAFISEIGIEASDL 1172
P+ +++ P S P P S LPTP Q + ++ ++ G +
Sbjct: 2790 SPSVRSMSGPESSP----PIGGPCEAAPSSSLPTPPQQPFIARRHIELGVTGGGSPENGD 2845
Query: 1173 SSLLEQFEKSEAKKECPPP----APADS-LAVGNSGGVDIPQEKRPLDRLQAPELANVAG 1227
+LL + ++ PP +PAD+ V + + + D + PE VA
Sbjct: 2846 GALLAITPPAVKRRRGRPPKKNRSPADAGRGVDEAPSSTLKGKTNGADPVPGPETLIVAD 2905
Query: 1228 --LTPPATPPHQLWKPLAAVSLLAKAKSPKSTAQEGTLKPEGVTEAKHPAAVRLQEGVHG 1285
L P P Q P V SP + G +P + P +
Sbjct: 2906 PVLEPQLIPGPQPLGP-QPVHRPNPLLSPVEKRRRG--RPPKARDLPIPGTIS------- 2955
Query: 1286 PSRVHVGSGDHDYCVRSRTPPKKM------PALVIPEVGSRWNVKRHQDITIKPVLSLGP 1339
+GD + R++ PP P LV P V T P G
Sbjct: 2956 ------SAGDGNSESRTQPPPHPSPLTPLPPLLVCPTATVANTVTTVTISTSPPKRKRGR 3009
Query: 1340 AAPPPPCIAASREPLDHRTSSEQADPSAPCLAPSSLLSPEASPCRNDMNTRTPPEPSAKQ 1399
PP S+ P+ R S+ + E+ +D + P A+
Sbjct: 3010 PPKNPPSPRPSQLPVLDRDSTSVLESCGLGRRRQPQGQGESEGSSSDEDGSRPLTRLARL 3069
Query: 1400 RSMRCYRKACRSASPSSQGWQGRRGRNSRSVSSGSNRTSEASS------------SSSSS 1447
R ++G +GR+ S V+ + A S S +
Sbjct: 3070 RL-------------EAEGMRGRKSGGSMVVAVIQDDLDLADSGPGGLELTPPVVSLTPK 3116
Query: 1448 SSSSRSRSRSLSPP---HKRWRRSSCSSSG-------RSRRCSSSSSSSSSSSSSSSSSS 1497
S+R R SL PP K R+ + + G R R S S S + +
Sbjct: 3117 LRSTRLRPGSLVPPLETEKLPRKRAGAPVGGSPGLAKRGRLQPPSPLGPEGSVEESEAEA 3176
Query: 1498 SSRSRSRSPSPRRRSDRRRRYSSYRSHDHYQRQRVLQ 1534
S +PRRR RR + D QR+L+
Sbjct: 3177 SGEEEEGDGTPRRRPGPRRLVGTTNQGD----QRILR 3209
Score = 54.7 bits (130), Expect = 7e-07
Identities = 136/618 (22%), Positives = 203/618 (32%), Gaps = 108/618 (17%)
Query: 819 LVPVGPSPASPSPEPPVSKPVASSPTEQVPSQE---MPLLARPSPPVQSVSPAVPTPPSM 875
L+ V +P P P P K + + VP QE + ++ P P+ V P P +
Sbjct: 974 LLEVATAP-DPPPRPKPVKMKVNRMLQPVPKQEGRTVVVVNNPRAPLGPVPVRPPPGPEL 1032
Query: 876 SAALPFPAGGLGMPPSLPPPPLQPPSLPLSMGPVLPDPFTHYAPLPSWPCYPHVSPSGYP 935
SA P P P + P SL +S P P P P P G
Sbjct: 1033 SA----------QPTPGPVPQVLPASLMVSASPAGP------------PLIPASRPPGPV 1070
Query: 936 CLPP--------PPTVPLVSGTPGAYAVPPTCSVPWAP-PPAPV-----SPYSSTCTYGP 981
LPP P +P G + PPT ++ P PPAPV P S+ P
Sbjct: 1071 LLPPLQPNSGSLPQVLPSPLGVLSGTSRPPTPTLSLKPTPPAPVRLSPAPPPGSSSLLKP 1130
Query: 982 LGWGPGPQHAP----------FWSTVPPPPLPPASIGRAVPQPKMESRGTPAGPPENVLP 1031
L PG P +T P P + R + P M++R P+G ++
Sbjct: 1131 LTVPPGYTFPPAAATTTSTTTATATTTAVPAPTPAPQRLILSPDMQAR-LPSGEVVSIGQ 1189
Query: 1032 LSMAPPLSLGLPGHGAPQTEPTKVEVKPVPASPHPKHKVSALVQSP-QMKALACVSAEGV 1090
L+ + G P T +++ + + +++ P Q + VSA G
Sbjct: 1190 LASLAQRPVANAGGSKPLT--FQIQGNKLTLTGAQVRQLAVGQPRPLQRNVVHLVSAGGQ 1247
Query: 1091 --TVEEPASERLKPETQETRPREKPPLPATKAVPTPRQSTVPKLPAVHPARLRKLSFLPT 1148
+ +PA L PTP + V LP+ P+ + L
Sbjct: 1248 HHLISQPAHVAL----------------IQAVAPTPGPTPVSVLPSSTPSTTPAPTGLSL 1291
Query: 1149 PRTQGSEDVVQAFISEIGIEASDLSSLLEQFEKSEAKKECPPPAPADSLAVGNSGGVDIP 1208
P + V ++ G+ ++ + + PP APA V P
Sbjct: 1292 P--LAANQVPPTMVNNTGV-----VKIVVRQAPRDGLTPVPPLAPAPRPPSSGLPAVLNP 1344
Query: 1209 QEKRPLDRLQAPELANVAGLTPPATPPHQLWK----PLAAVSLLAKAKSPKSTAQEGTLK 1264
+ RL P L P T L K P VS A +P + + +
Sbjct: 1345 RPTLTPGRLPTPTLGTARAPMPTPTLVRPLLKLVHSPSPEVSASAPGAAPLTISSPLHVP 1404
Query: 1265 PEGVTEAKHPAAVRLQEGVHGPSRVHVG---SGDHDYCVRSRTPPKKMPALVIPEVGSRW 1321
A P + + P V S V + P L IP + +
Sbjct: 1405 SSLPGPASSPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIP-ISAPL 1463
Query: 1322 NVKRHQDITI----KPVLSLGPAAPPPPCIAASREPLDHRTSSEQADPSAPCLAPSSLLS 1377
V + P+ + PAAP PP +A S A PSA L +
Sbjct: 1464 TVSASGPALLTSVTPPLAPVVPAAPGPPSLAPS-----------GASPSASALTLGLATA 1512
Query: 1378 PEASPCRNDMNTRTPPEP 1395
P S +++TP P
Sbjct: 1513 PSLS------SSQTPGHP 1524
Score = 44.3 bits (103), Expect = 0.001
Identities = 145/656 (22%), Positives = 206/656 (31%), Gaps = 164/656 (25%)
Query: 624 PLPAEPVLINPVLADSAAVDPAVVPISDNLP----------PVDAVPSGPAPVDL----- 668
P PA P A +A VP+S +P PV +PS P P +
Sbjct: 2437 PRPAPRPRPTPASAPAAIPALVPVPVSAPVPISAPNPITILPVHILPSPPPPSQIPPCSS 2496
Query: 669 -------ALVDPVPND--------LTPVDPVLVKSRPTDPRRGAVSSALGGSAP------ 707
A P + +TP P+L+ P+ P +V++ G P
Sbjct: 2497 PACTPPPACTPPPAHTPPPAQTCLVTPSSPLLL-GPPSVPISASVTNLPLGLRPEAELCA 2555
Query: 708 QLLVESESLD---------------PPKTIIPEVKEVVDSLKIESGTSATTHEARPRPLS 752
Q L ESL+ PPK ++P E+ L + + T A L
Sbjct: 2556 QALASPESLELASVASSETSSLSLVPPKDLLPVAVEI---LPVSEKNLSLTPSAPSLTLE 2612
Query: 753 LSEYRRRRQQRQAETEERSPQPPTGKWPSLPETPTGLADIPCLVIPPAPAKKTALQRSPE 812
++Q ++ E + P E P +++ L +PP+ A LQ E
Sbjct: 2613 AGSIPNGQEQEAPDSAEGTTLTVL---PEGEELPLCVSESNGLELPPSAASDEPLQEPLE 2669
Query: 813 TPLEICLVPVGPSPASPSPEPPVSKPVASSPTEQVPSQEMPLLARPSPPVQSVSPAVPTP 872
+ +P S SPE P A PS + P P SPA P
Sbjct: 2670 ADRTSEELTEAKTPTS-SPEKPQELVTAE---VAAPSTSSSATSSPEGP----SPARPPR 2721
Query: 873 PSMSAALPFPAGGLGMPPSLPPPPLQPPSLPLSMGPVLPDP------------------- 913
SA + G G P PP P LP + V+ +
Sbjct: 2722 RRTSADVEIRGQGTGR-PGQPPGPKVLRKLPGRLVTVVEEKELVRRRRQQRGAASTLVPG 2780
Query: 914 FTHYAPLPSWPCYPHVS------PSGYPC-------LPPPPTVPLVS-----------GT 949
+ + P P +S P G PC LP PP P ++ G+
Sbjct: 2781 VSETSASPGSPSVRSMSGPESSPPIGGPCEAAPSSSLPTPPQQPFIARRHIELGVTGGGS 2840
Query: 950 P----GAY--AVPPTCSVPWAPPPAPVSPYSSTCTYGPLGWGPGPQHAPF------WSTV 997
P GA PP PP P G G AP +
Sbjct: 2841 PENGDGALLAITPPAVKRRRGRPPKK--------NRSPADAGRGVDEAPSSTLKGKTNGA 2892
Query: 998 PPPPLPPASIGRAVPQPKMESRGTPAGPPENVLPLSMAPPLSLGLPGHGAPQTEPTKVEV 1057
P P P I V P +E + P P P+ PL P + P K
Sbjct: 2893 DPVPGPETLI---VADPVLEPQLIPGPQPLGPQPVHRPNPLL--SPVEKRRRGRPPKARD 2947
Query: 1058 KPVPAS----------------PHPKHKVSALVQSPQMKALACVSAE-GVTVEEPASERL 1100
P+P + PHP S L P + L C +A TV
Sbjct: 2948 LPIPGTISSAGDGNSESRTQPPPHP----SPLTPLPPL--LVCPTATVANTVTTVTISTS 3001
Query: 1101 KPETQETRPREKPPLPATKAVPTPRQSTVPKLPAVHPARLRKLSFLPTPRTQGSED 1156
P+ + RP + PP P +P + + L + R R+ P+ QG +
Sbjct: 3002 PPKRKRGRPPKNPPSPRPSQLPVLDRDSTSVLESCGLGRRRQ------PQGQGESE 3051
Score = 35.4 bits (80), Expect = 0.47
Identities = 109/481 (22%), Positives = 161/481 (33%), Gaps = 104/481 (21%)
Query: 516 QGKGKPRAWARAWAAALENSS-----PKNLERSAGQSSPAKEGPLDLYPKLAD-TIQTNP 569
Q P + A A+ E SS PK+L A + P E L L P T++
Sbjct: 2556 QALASPESLELASVASSETSSLSLVPPKDLLPVAVEILPVSEKNLSLTPSAPSLTLEAGS 2615
Query: 570 IP-------------THLSLVDSAQASPMPV---DSVEADPTAVGPV-LAGPVPVDPGLV 612
IP T L+++ + P+ V + +E P+A L P+ D
Sbjct: 2616 IPNGQEQEAPDSAEGTTLTVLPEGEELPLCVSESNGLELPPSAASDEPLQEPLEADRTSE 2675
Query: 613 DLAS----TSS-----ELVEPLPAEPVLINPVLADSAAVDPAVVPISDNLPPVDAVPSGP 663
+L TSS ELV A P + + PA P V+ G
Sbjct: 2676 ELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGPSPARPPRRRTSADVEIRGQGT 2735
Query: 664 A----PVDLALVDPVPNDLTPVDPVLVKSRPTDPRRGAVSSALGGSAPQLLVESESLDPP 719
P ++ +P L V R +RGA S+ + G V S P
Sbjct: 2736 GRPGQPPGPKVLRKLPGRLVTVVEEKELVRRRRQQRGAASTLVPG------VSETSASPG 2789
Query: 720 KTIIPEVKEVVDSLKIESGTSATTHEARPRPLSLSEYRRRRQQRQAETEERSPQ------ 773
+ + S I A + P P + RR T SP+
Sbjct: 2790 SPSVRSMSGPESSPPIGGPCEAAPSSSLPTPPQ-QPFIARRHIELGVTGGGSPENGDGAL 2848
Query: 774 ----PPT-----GKWPSLPETPT----GLADIPCLVIP-------PAPAKKTALQRSPET 813
PP G+ P +P G+ + P + P P +T + P
Sbjct: 2849 LAITPPAVKRRRGRPPKKNRSPADAGRGVDEAPSSTLKGKTNGADPVPGPETLIVADPV- 2907
Query: 814 PLEICLVPVGPSPASPSP---EPPVSKPVASSPTEQVP-SQEMPLL------------AR 857
LE L+P GP P P P P+ PV + P ++++P+ +R
Sbjct: 2908 -LEPQLIP-GPQPLGPQPVHRPNPLLSPVEKRRRGRPPKARDLPIPGTISSAGDGNSESR 2965
Query: 858 PSPPVQSVSPAVPTPP--------------SMSAALPFPAGGLGMPPSLPPPPLQPPSLP 903
PP SP P PP +++ + P G PP PP P +P LP
Sbjct: 2966 TQPPPHP-SPLTPLPPLLVCPTATVANTVTTVTISTSPPKRKRGRPPKNPPSP-RPSQLP 3023
Query: 904 L 904
+
Sbjct: 3024 V 3024
>gi|169205253 PREDICTED: hypothetical protein [Homo sapiens]
Length = 3859
Score = 88.2 bits (217), Expect = 6e-17
Identities = 154/605 (25%), Positives = 225/605 (37%), Gaps = 85/605 (14%)
Query: 548 SPAKEGPLDLYPKLADTIQTNPIPTHLSLVDSAQASPMPVDSVEADPTAVGPVLAGPVPV 607
+PA + + P + P T S V SA +PV S ++ V P + VPV
Sbjct: 2209 TPADSPIVPVPPASDPVVPVTPADTPGSPVASADGPVVPVTSADSPLVPVTPGDSPVVPV 2268
Query: 608 DPGLVDLASTSSELVEPLPAEPVLI--NPVLADSAAVDPAVVPISDNLPPVDAVPSGPAP 665
P + +S P PV + +PV + A DP + P+S PV VP PA
Sbjct: 2269 TPADSPVFPVTS---ADGPVFPVTLADDPVFPVTPADDP-IFPVSPADSPV--VPVTPAN 2322
Query: 666 VDLALVDPVPNDLTPVDPVLVKSRPTDPRRGAVSSALGGSAPQLLVESESLDPPKTIIPE 725
+ + V P + PV P P G V L S L+V L P IP
Sbjct: 2323 IPVVPVPPANGSVVPVTSAGSPFVPIIPADGLV--VLDSSTDVLVV----LVSPTDGIP- 2375
Query: 726 VKEVVDSLKIESGTSATTHEARPRPLSLSEYRRRRQQRQAETEERSPQPPTGKWPSLPET 785
V L + S TT ++ P+ T SP P P
Sbjct: 2376 ----VPDLADDPVVSVTTSDSPVIPV---------------TPTDSPVVPVAPADG-PVV 2415
Query: 786 PTGLADIPCLVIPPAPAKKTALQRSPETPLEICLVPVGPSPASPSPEPPVSKPVASSPTE 845
P D P V+P PA + P TP + +V PA+P+ +P VS A P
Sbjct: 2416 PVTSVDSP--VVPVTPADSPVI---PVTPADSLVV-----PATPADDPVVSVTPADGPVV 2465
Query: 846 QVPSQEMPLLARPSPPVQSVSPAVPTPPSMSAALPFPAGGLGMPPSLPPP----PLQPPS 901
V + ++P+++ S + SP VP P+ +P + + P+ P P+ P
Sbjct: 2466 PVTTADIPVISVTS----ADSPVVPVTPADGLVVPVTSADSVVVPATPADCPLVPVDPAD 2521
Query: 902 LPLSMGPVLPDPFTHYAPLPSWPCYPHVSPSGYPCLPPPPT-VPLVSGTPGAYAVPPTCS 960
P+ + +P S P +P V+P+ +P P VP+V TPG
Sbjct: 2522 SPIVLFTPYDNPVVSVTSDDS-PVFP-VTPADSSVVPVTPAGVPVVPVTPG--------- 2570
Query: 961 VPWAPPPAPVSPYSSTCTYGPLGWGPGPQHAPFWSTVPPPPLPPASIGRAVPQPKMESRG 1020
P PV+P S P+ P + P P+ PA VP +S
Sbjct: 2571 ---DGPVVPVTPADSLVV--PVTSADSPVFPVTPADSPVFPVSPAD-DLVVPVTPGDSPV 2624
Query: 1021 TPAGPPEN--VLPLSMAPPLSLGLPGHGAPQTEPTKVEVKPVPASPHPKHKVSALVQSPQ 1078
P P ++ VL P+ P +G P T + VP P + L S
Sbjct: 2625 VPVSPADSPVVLVTPADGPVVPVTPANG-PVVPVTSADSPFVPVI--PADGLVVLDSSTD 2681
Query: 1079 MKALACVSAEGVTVEEPASERLKPETQ------ETRPREKPPLPATKAVPTPRQSTVPKL 1132
+ + +G+ V + A + + P T P + P +P T A P VP
Sbjct: 2682 VLVVPVFPTDGILVPDLADDPVVPVTPGDDPVVPVTPGDDPVIPVTPADDGP---FVPVT 2738
Query: 1133 PAVHP 1137
PAV P
Sbjct: 2739 PAVGP 2743
Score = 85.5 bits (210), Expect = 4e-16
Identities = 173/715 (24%), Positives = 258/715 (36%), Gaps = 104/715 (14%)
Query: 575 SLVDSAQASPMPVDSVEADPTAVGPVLAGPVPV---DPGLVDLASTSSELVEPLPAEPVL 631
S V SA +PV S ++ P V P VPV D + ++S +V PA+
Sbjct: 1728 SPVTSADGPVVPVTSADSLPVPVTPADGPVVPVTSADGPVAPVSSADGPVVPVTPAD--- 1784
Query: 632 INPVLADSAAVDPAVVPISDNLPPVDAVPSGPAPV------DLALVDPVPND-------- 677
+PV+ + A DP V P++ PV VP P+ D V +P D
Sbjct: 1785 -SPVVPVTTADDPTV-PVTPADSPVVPVPPANGPIVPVTSADSPFVPVIPADGLVVLDSS 1842
Query: 678 -------LTPVDPVLVKSRPTDPRRGAVSSALGGSAPQLLVESESLDPPKTIIPEVKEVV 730
++P D +LV DP VS + S + ++S P + P VV
Sbjct: 1843 TDVLVVPVSPTDGILVPDLADDP---VVSVTIADSPVIPVTPADS--PVVLVTPADGPVV 1897
Query: 731 DSLKIESGTSATTHEARP----RPLSLSEYRRRRQQRQAETEERSPQPPTGKWPS-LPET 785
+++ T P P+ + P P+ P
Sbjct: 1898 PVTSVDNPVVPVTPADNPVIPVTPVDDPVVPVTPADDPIVPVTSADSPIVSVTPADSPVF 1957
Query: 786 PTGLADIPCLVIPPAPAKKTALQRSPETPLEICLVPVGPS-----PASPSPEPPVSKPVA 840
P AD P VIP A A + P TP ++ +VPV P+ P +P+ P +
Sbjct: 1958 PVTPADSP--VIPVASADSPLV---PVTPADMVVVPVIPADGPVIPVTPAESPAIPVTPT 2012
Query: 841 SSPTEQVPSQEMPLLARPSPPVQSVSPAVPTPPSMSAALPFPAGGLGMPPSLPPPPLQPP 900
SP V S + P++ PV + SP VP P+ S +P PP P+ P
Sbjct: 2013 DSPVVPVTSADSPVI-----PVTADSPFVPVTPADSPVIPV------TPPDDLVVPVTPI 2061
Query: 901 SLPLSMGPVLPDPFTHYAPLPSWPCYPHVSPSGYPCLP-PPPTVPLVSGTPGAYAVPPTC 959
P+ ++ P P S P P V+P+ P +P P P++ TP + P
Sbjct: 2062 DCPVVPVTLVDCPVVSVTPANS-PVDP-VTPADGPVVPVTPADSPVIPVTPADDLIVPVT 2119
Query: 960 S--------VPWAPPPAPVSPYSSTCTYGPLGWGPGPQHAPFWSTVPPPPLPPASIGRAV 1011
P P PV+P S P P + V P+ PA G +
Sbjct: 2120 PADSLIVSVTPADSPVVPVTPADSPVISVASADSPVVPVTPADTVV--VPVTPAD-GPVI 2176
Query: 1012 PQPKMESRGTPAGPPEN-VLPLSMAPPLSLGLPGHGAP--QTEPTKVEVKPVPASPHPKH 1068
P ES P P ++ V+P++ A + + +P P V PV + P
Sbjct: 2177 PVTPAESPAIPVTPADSPVVPVTPADDPVVPVTPADSPIVPVPPASDPVVPVTPADTP-- 2234
Query: 1069 KVSALVQSPQMKALACVSAEGVTVE-EPASERLKPETQETRPREKPPLPATKA------V 1121
+ V S + SA+ V P + P T P + P P T A V
Sbjct: 2235 --GSPVASADGPVVPVTSADSPLVPVTPGDSPVVPVT----PADSPVFPVTSADGPVFPV 2288
Query: 1122 PTPRQSTVPKLPAVHPARLRKLSFLPTPRTQGSEDVVQAFISEIGIEASDLSSLLEQFEK 1181
P PA P F +P V A I + + ++ S +
Sbjct: 2289 TLADDPVFPVTPADDPI------FPVSPADSPVVPVTPANIPVVPVPPANGSVV----PV 2338
Query: 1182 SEAKKECPPPAPADSLAVGNSGGVDIPQEKRPLDRLQAPELAN--VAGLTPPATP 1234
+ A P PAD L V +S + P D + P+LA+ V +T +P
Sbjct: 2339 TSAGSPFVPIIPADGLVVLDSSTDVLVVLVSPTDGIPVPDLADDPVVSVTTSDSP 2393
Score = 84.0 bits (206), Expect = 1e-15
Identities = 198/792 (25%), Positives = 273/792 (34%), Gaps = 128/792 (16%)
Query: 574 LSLVDSAQASPMPVDS-VEADPTAVGPVLAGP------VPVDP--GLVDLASTSSELVEP 624
++L DS P DS V P A GPV+ VPV P GLV L S++ LV P
Sbjct: 1161 VTLADSPVVPVTPADSPVIPVPPANGPVVPVSSADSPFVPVIPADGLVVLDSSTDVLVVP 1220
Query: 625 LPAEPVLINPVLADSAAV---------------DPAVVPISDNLPPVDAVPSGPAPVDLA 669
+ ++ P LAD V D VVP++ PV V +PV L
Sbjct: 1221 VSPTDGILVPDLADDPVVSVTIADSPVIPVTPADSPVVPVTSADSPVVPVTPADSPVILV 1280
Query: 670 L-VDPVPNDLTPVDPVLVKSR----------------PTDPRRGAVSSALGGSAPQLLVE 712
V PV + T PV++ S P P G V +P + V
Sbjct: 1281 TPVGPVVSVTTADGPVVLVSTADSPVIPVTSADSPVVPVTPADGPVVPVTSADSPFVPV- 1339
Query: 713 SESLDPPKTIIPEVKEVVDSLKIESGTSATTHEARPRPLSLSEYRRRRQQRQAETEERSP 772
+ + DP + P +V ES T P T SP
Sbjct: 1340 TPADDPIVPVTPADSPIVSVTPAESPAIPVTPADSP--------------VVPVTSADSP 1385
Query: 773 QPP--TGKWPSLPETPTGLADIPCLV--IPPAPAKKTALQRSPETPLEICLVPVGPSPAS 828
P T +P TPTG +P P +P P TP +VPV P+
Sbjct: 1386 LIPLTTAGSRVVPVTPTGDPIVPVTPADTPGSPVTSADGPVVPVTPAGDPIVPVTPADTP 1445
Query: 829 PSPEPPVSKPVASSPTEQVPSQEMPLLARPSPPVQSV-SPAVPTPPSMSAALPFPAGGLG 887
SP PV T P + P PV S P VP P+ S +P
Sbjct: 1446 GSPVTSADGPVVPVTTPDGPLVPVSPPDGPVVPVTSADGPVVPVTPADSPFIPVTTAD-- 1503
Query: 888 MPPSLPPPPLQPPSLPLSMG--PVLP-----DPFTHYAPLPSWPCYPHVSPSGYPCLPPP 940
P +P P P +P++ PV+P P H P P + G L
Sbjct: 1504 -DPIVPVTPADSPVVPVTPADIPVVPVTPANGPVIHVTS-ADCPFVPVIPADGLVALDSS 1561
Query: 941 PTVPLVSGTP-GAYAVP-----PTCSVPWAPPPA-PVSPYSSTCTYGPLGWGP------- 986
V +V +P VP P SV A P PV+P ST L GP
Sbjct: 1562 TDVLVVPVSPTDGVLVPDLADDPVVSVTIADSPVIPVTPADSTVVPVTLADGPVVPVTSV 1621
Query: 987 -------GPQHAPFWSTVPPPPLPPASI----GRAVPQPKMESRGTPAGPPEN-VLPLSM 1034
P + P + V P P S+ G VP + P P + V+P++
Sbjct: 1622 DIPVVPVTPANGPV-APVTPVDDPVVSVNPADGSVVPVTSADCPVVPVTPADGLVVPVTP 1680
Query: 1035 APPLSLGLPGHGAPQTEPTKVEVKPVPASPHPKHKVSALVQSPQMKALACVSAEGVTVEE 1094
A + + +P T + +P +P V SA+G V
Sbjct: 1681 ADSPIVPVTPADSPVVLVTSADSPVIPVTPADSPVVPVTSADTDSPGSPVTSADGPVVPV 1740
Query: 1095 PASERLK-PETQETRPREKPPLPATKA------VPTPRQSTVPKLPAVHPARLRKLSFLP 1147
+++ L P T P + P +P T A V + VP PA P + P
Sbjct: 1741 TSADSLPVPVT----PADGPVVPVTSADGPVAPVSSADGPVVPVTPADSPVVPVTTADDP 1796
Query: 1148 T-PRTQGSEDVVQAFISEIGIEASDLSSLLEQFEKSEAKKECPPPAPADSLAVGNSGGVD 1206
T P T VV + I + A P PAD L V +S
Sbjct: 1797 TVPVTPADSPVVPVPPANGPI-----------VPVTSADSPFVPVIPADGLVVLDSSTDV 1845
Query: 1207 IPQEKRPLDRLQAPELAN--VAGLTPPATPPHQLWKPLAAVSLLAKAKSP--KSTAQEGT 1262
+ P D + P+LA+ V +T +P + + V L+ A P T+ +
Sbjct: 1846 LVVPVSPTDGILVPDLADDPVVSVTIADSPVIPVTPADSPVVLVTPADGPVVPVTSVDNP 1905
Query: 1263 LKPEGVTEAKHP 1274
+ P VT A +P
Sbjct: 1906 VVP--VTPADNP 1915
Score = 82.4 bits (202), Expect = 3e-15
Identities = 165/622 (26%), Positives = 233/622 (37%), Gaps = 99/622 (15%)
Query: 548 SPAKEGPLDLYPKLADTIQTNPIPTHLSLVDSAQASPMPVDSVEADPTAVGPVLAGPVPV 607
+PA + P + P + L V A ++ +PV + V P VPV
Sbjct: 162 TPADSPVFPVTPADSPLFPVTPADSPLFPVTPADSAAIPVTPADGPVVHVTPANGTVVPV 221
Query: 608 DPG---LVDLASTSSELVEPLPAEPVLINPVLADSAAVDPAVVPISDNLPPVDAVPS-GP 663
P +V +AST S +V PA+ ++ ADS+ V IS + P V +P+ GP
Sbjct: 222 TPADSPVVTVASTDSPVVPVTPADDPIVPVTPADSSFVP----VISADSPFVPVIPADGP 277
Query: 664 APVDLALVDPVPNDLTPVDPVLVKSRPTDPRRGAVSSALGGSAPQLLVESESLDPPKTII 723
VD + D + + PV+ +LV P + L+V + D P I+
Sbjct: 278 VVVD-SSTDVLVVPVFPVNCILV------PAFADETIXXXXXXXSLVVSVTTADDP--IV 328
Query: 724 PEVKEVVDSLKIESGTSATTHEARPRPLSLSEYRRRRQQRQAETEERSPQPPT--GKWPS 781
P DS + S T ++ P+ T SP P P
Sbjct: 329 PVTP--ADSPVL----SVTLADSPVVPV---------------TPADSPFVPAIPADGPV 367
Query: 782 LPETPTGLADIPCLVIPPA--PAKKTALQRSPETPLEICLVPVGPSPASPSPEPPVSKPV 839
+P TP AD P + + PA P A SP P+ +P+ +P VS
Sbjct: 368 VPVTP---ADSPVVPVTPADGPVVSVASADSPFVPV------------TPADDPIVSVTP 412
Query: 840 ASSPTEQVPSQEMPLL------ARPSPPVQSVSPAVPTPPSMSAALPF-PAGGLGMPPSL 892
A SP V S + PL+ R P + P VP P+ + P A G +P +
Sbjct: 413 ADSPVVPVTSADSPLIPVTTADGRVVPVTAAGDPIVPVTPADTPGSPVTSADGPVVPVTS 472
Query: 893 PPPPLQPPSLPLSMGPVLPDPFTH--YAPLPS--WPCYPHVSPSGYPCLPPPPTVPLVSG 948
PL P + P GPV+P AP+ S P P V+P+ P +P L+
Sbjct: 473 ADIPLVPVTPP--DGPVVPVTSADGPVAPVSSADGPVVP-VTPADSPFIPVTTADDLI-- 527
Query: 949 TPGAYAVPPTCSVPWAPPPA-PVSPYSSTCTYGPLGWGPGPQHAPFWSTVPPPPLPPASI 1007
P A P SV A PA PV+P S P+ GP + P P+ PA
Sbjct: 528 VPVTPADSPVLSVTPAESPAIPVTPADSPIV--PVTPANGPVVPVTSADSPFVPVIPAD- 584
Query: 1008 GRAVPQPKMESRGTPAGPPENVLPLSMAPPLSLGLPGHGAPQTEPTKVEVKPVPASPHPK 1067
G VP +S P P + +P LS+ L A P V PV + P
Sbjct: 585 GPVVPVTPADSPVVPVTPAD-------SPVLSVTLADSPAVPVTPADSPVVPVTPADGPV 637
Query: 1068 HKVSALVQSPQMKALACVSAEGVTVEEPASERLKPETQETRP------REKPPLPATKA- 1120
V A SP + + + + PA P TQ P ++P +P T A
Sbjct: 638 VPV-ASADSPFVPVTP--ADDPIVSVTPAESPAIPVTQADSPVVPVTSADRPVIPVTTAD 694
Query: 1121 -----VPTPRQSTVPKLPAVHP 1137
V VP PA P
Sbjct: 695 GRIVPVTAAGDPIVPVTPADTP 716
Score = 77.0 bits (188), Expect = 1e-13
Identities = 153/637 (24%), Positives = 223/637 (35%), Gaps = 115/637 (18%)
Query: 557 LYPKLADT--IQTNPIPTHLSLVDSAQASPMPVDSVEADPTAVGPVLAGPVPVDPGLVDL 614
L P AD + P + V A + +PV S + DP V P+ P D +V +
Sbjct: 79 LVPDFADNPVVPVTPADDLVFPVTPADSPVIPVTSAD-DP--VVPI----TPADNPVVPV 131
Query: 615 ASTSSELVEPLPAEPVLINPVLADSAAVDPAVVPISDNLPPVDAVPSGPAPVDLALVDPV 674
S + ++ PA+ + PV A+ D VVP++ PV P PA L V P
Sbjct: 132 TSANGPVIPVTPADSPVF-PV----ASADGPVVPVTPADSPV--FPVTPADSPLFPVTPA 184
Query: 675 PNDL---TPVDPVLVKSRPTD-------PRRGAVSSALGGSAPQLLVESESL-------- 716
+ L TP D + P D P G V +P + V S
Sbjct: 185 DSPLFPVTPADSAAIPVTPADGPVVHVTPANGTVVPVTPADSPVVTVASTDSPVVPVTPA 244
Query: 717 -DPPKTIIPEVKEVVDSLK----------------IESGTSATTHEARP-RPLSLSEYRR 758
DP + P V + ++S T P + + +
Sbjct: 245 DDPIVPVTPADSSFVPVISADSPFVPVIPADGPVVVDSSTDVLVVPVFPVNCILVPAFAD 304
Query: 759 RRQQRQAETEERSPQPPTGKWPSLPETPTG-------LADIPCLVIPPAPAKKTALQRSP 811
T P +P TP LAD P V+P PA + P
Sbjct: 305 ETIXXXXXXXSLVVSVTTADDPIVPVTPADSPVLSVTLADSP--VVPVTPADSPFV---P 359
Query: 812 ETPLEICLVPVGPS-----PASPSPEPPVSKPVASSPTEQVPSQEMPLLA-----RPSPP 861
P + +VPV P+ P +P+ P VS A SP V + P+++ P P
Sbjct: 360 AIPADGPVVPVTPADSPVVPVTPADGPVVSVASADSPFVPVTPADDPIVSVTPADSPVVP 419
Query: 862 VQSV-SPAVPTPPSMSAALPFPAGGLGMPPSLPPPPLQPPSLPLSM--GPVLPDPFTHYA 918
V S SP +P + +P A G P +P P P P++ GPV+P A
Sbjct: 420 VTSADSPLIPVTTADGRVVPVTAAG---DPIVPVTPADTPGSPVTSADGPVVP---VTSA 473
Query: 919 PLPSWPCYPHVSPSGYPCLPPPPTVPLVSGTPGAYAVPPTCSVPWAPPPAPVSPYSSTCT 978
+P P P P P VP V+ G A + P P SP+ T
Sbjct: 474 DIPLVPVTP----------PDGPVVP-VTSADGPVAPVSSADGPVVPVTPADSPFIPVTT 522
Query: 979 YGPLGWGPGPQHAPFWSTVPPP--------------PLPPASIGRAVPQPKMESRGTPAG 1024
L P +P S P P+ PA+ G VP +S P
Sbjct: 523 ADDLIVPVTPADSPVLSVTPAESPAIPVTPADSPIVPVTPAN-GPVVPVTSADSPFVPVI 581
Query: 1025 PPEN-VLPLSMAPPLSLGLPGHGAPQTEPTKVEVKPVPASPHPKHKVSALVQSPQMKALA 1083
P + V+P++ A + + +P T + VP +P V + +A
Sbjct: 582 PADGPVVPVTPADSPVVPVTPADSPVLSVTLADSPAVPVTPADSPVVPVTPADGPVVPVA 641
Query: 1084 CVSAEGVTVEEPASERLKPETQETRPREKPPLPATKA 1120
+ V V PA + + T P E P +P T+A
Sbjct: 642 SADSPFVPV-TPADDPIVSVT----PAESPAIPVTQA 673
Score = 77.0 bits (188), Expect = 1e-13
Identities = 179/715 (25%), Positives = 256/715 (35%), Gaps = 124/715 (17%)
Query: 574 LSLVDSAQASPMPVDS-VEADPTAVGPVLAGPV-PVDPGLVDLASTSSELVEPLPAEPVL 631
++LVD S P +S V+ A GPV+ PV P D ++ + +V PA+ ++
Sbjct: 2068 VTLVDCPVVSVTPANSPVDPVTPADGPVV--PVTPADSPVIPVTPADDLIVPVTPADSLI 2125
Query: 632 INPVLADSAAVDPAVVPISDNLPPVDAVPSGPAPVDLALVDPVPNDLTPVDPVLVKSRPT 691
++ ADS VVP++ PV +V S +PV VP +TP D V+V P
Sbjct: 2126 VSVTPADS-----PVVPVTPADSPVISVASADSPV-------VP--VTPADTVVV---PV 2168
Query: 692 DPRRGAVSSALGGSAPQLLVESESLDPPKTIIPEVKEVVDSLKIESGTSATTHEARPRPL 751
P G V +P + V + + P + P VV +S + P
Sbjct: 2169 TPADGPVIPVTPAESPAIPV-TPADSPVVPVTPADDPVVPVTPADSPIVPVPPASDP--- 2224
Query: 752 SLSEYRRRRQQRQAETEERSPQPPTGKWPSLPETPTGLADIPCLVIPPAPAKKTALQRSP 811
T +P P P P AD P + + P SP
Sbjct: 2225 -----------VVPVTPADTPGSPVASADG-PVVPVTSADSPLVPVTPGD--------SP 2264
Query: 812 ETPLEICLVPVGPSPASPSPEPPVSKPVASSPTEQVPSQEMPL--LARPSPPVQSVSPA- 868
P+ PV P ++ P PV+ +A P V + P+ ++ PV V+PA
Sbjct: 2265 VVPVTPADSPVFPVTSADGPVFPVT--LADDPVFPVTPADDPIFPVSPADSPVVPVTPAN 2322
Query: 869 ---VPTPPSMSAALPFPAGGLGMPPSLPPPPLQPPSLPLSMGPVLPDPFTHYAPLPSWPC 925
VP PP+ + +P + G P +P L + VL P T P+P
Sbjct: 2323 IPVVPVPPANGSVVPVTSAGSPFVPIIPADGLVVLDSSTDVLVVLVSP-TDGIPVPDLAD 2381
Query: 926 YPHVS--PSGYPCLPPPPT-VPLVSGTPGAYAVPPTCSV--------PWAPPPAPVSPYS 974
P VS S P +P PT P+V P V P SV P P PV+P
Sbjct: 2382 DPVVSVTTSDSPVIPVTPTDSPVVPVAPADGPVVPVTSVDSPVVPVTPADSPVIPVTPAD 2441
Query: 975 STCTYGPLGWGPGPQHAPFWSTV------------------PPPPLPPASIGRAVPQPKM 1016
S P P V P P+ PA G VP
Sbjct: 2442 SLVVPATPADDPVVSVTPADGPVVPVTTADIPVISVTSADSPVVPVTPAD-GLVVPVTSA 2500
Query: 1017 ESRGTPAGPPE-NVLPLSMA-PPLSLGLPGHGAPQTEPTKVEVKPVPASPHPKHKVSALV 1074
+S PA P + ++P+ A P+ L P + P T + P +P V V
Sbjct: 2501 DSVVVPATPADCPLVPVDPADSPIVLFTP-YDNPVVSVTSDDSPVFPVTPADSSVVP--V 2557
Query: 1075 QSPQMKALACVSAEGVTVE-EPASERLKPETQ------ETRPREKPPLPATKA----VP- 1122
+ + +G V PA + P T P + P P + A VP
Sbjct: 2558 TPAGVPVVPVTPGDGPVVPVTPADSLVVPVTSADSPVFPVTPADSPVFPVSPADDLVVPV 2617
Query: 1123 TPRQS-TVPKLPAVHPARLRKLSFLPTPRTQGSEDVVQAFISEIGIEASDLSSLLEQFEK 1181
TP S VP PA P L TP V A + + ++D +
Sbjct: 2618 TPGDSPVVPVSPADSPV------VLVTPADGPVVPVTPANGPVVPVTSADSPFV------ 2665
Query: 1182 SEAKKECPPPAPADSLAVGNSGGVDIPQEKRPLDRLQAPELAN--VAGLTPPATP 1234
P PAD L V +S + P D + P+LA+ V +TP P
Sbjct: 2666 --------PVIPADGLVVLDSSTDVLVVPVFPTDGILVPDLADDPVVPVTPGDDP 2712
Score = 73.9 bits (180), Expect = 1e-12
Identities = 150/569 (26%), Positives = 211/569 (37%), Gaps = 112/569 (19%)
Query: 548 SPAKEGPLDLYPKLADTIQTNPIPTHLSLVDSAQASPMPVDSVEADPTAVGPVLAGPVPV 607
SPA + + + P + + +P + + LV A +PV V + VPV
Sbjct: 2608 SPADDLVVPVTPGDSPVVPVSPADSPVVLVTPADGPVVPVTPANGPVVPVTSADSPFVPV 2667
Query: 608 DP--GLVDLASTSSELVEPL-PAEPVLINPVLADSAAVDPAVVPISDNLPPVDAVPSGPA 664
P GLV L S++ LV P+ P + +L+ P LAD DP VVP++ PV V G
Sbjct: 2668 IPADGLVVLDSSTDVLVVPVFPTDGILV-PDLAD----DP-VVPVTPGDDPVVPVTPGDD 2721
Query: 665 PVDLALVDPVPNDLTPVDPVLVKSRPTDPRRGAVSSALGGSAPQLLVESESLDPPKTIIP 724
PV + P D P PV P P A S + P L + DP ++ P
Sbjct: 2722 PV----IPVTPADDGPFVPVTPAVGPVVPDLTADDSVV----PDSLTD----DPVISVCP 2769
Query: 725 EVKEVVDSLKIESGTSATTHEARPRPLSLSEYRRRRQQRQAETEERSPQPPTGKWPSLPE 784
+ D L + R ++ E S P TG P
Sbjct: 2770 D-----DGLVVPDTV-----------------------RDSDGPEVSVYPVTG-----PV 2796
Query: 785 TPTGLADIPCLVIP------------PAPAKKTALQRSPETPLEICLVPVGPSPASPSPE 832
AD P + +P PA ++ P + PV +P+ P
Sbjct: 2797 VTDSAADCPVVSVPLTDGLVVLCPPDEVPAVHDSVTNGLVVPDPVIDGPVFSNPSVDGPI 2856
Query: 833 PPVSKPVASSPTEQVPSQEMPLLARPSP--PVQSVSPA-----VPTPPSMSAALPFPAGG 885
PV+ A +P P + P++ +PS PV + +PA + TP + P G
Sbjct: 2857 VPVAS--ADNPGVPDPIRAFPVVPKPSTFSPVVTSTPADWIDVIVTPADCADVPVNPVNG 2914
Query: 886 LGMP------PSLPPPP------LQPP-------SLPLSMGPVLPDPFTHYAPLPSWPCY 926
+P P +P PP L PP S P++ GPV+ DP T +P P
Sbjct: 2915 PVVPDLSGDCPVVPVPPTDDIVVLNPPDVVFAVVSTPVTDGPVVTDPATDGLMVPVTPAN 2974
Query: 927 PHVSP---SGYPCLPPPPTVPLVSGTPGAYAVPPTCSVPWAPPPAPVSPYSSTCTYGPLG 983
V+P S YP + TV GT V PT P P P+ S S T L
Sbjct: 2975 GSVAPVTLSEYPDV----TVTPADGT----VVSPTIGGPVVPDPSADSSVVSNPTTDGL- 3025
Query: 984 WGPGPQHAPFWSTVPPPPLPPASIGRAVPQPKMESRGTPAGPPENVLPLSMAPPLSLGLP 1043
P P A V P P A + + + TPA P V + P+
Sbjct: 3026 IVPNPLLAGPVVPVTPTDGPLAPV---ILADCPDVTVTPADGPV-VCAFTTGGPVFPDPT 3081
Query: 1044 GHGAPQTEPTKVEVKPVPASPHPKHKVSA 1072
G + PT + PV +P K VSA
Sbjct: 3082 AEGLVVSNPTVDD--PVVTNPSTKGLVSA 3108
Score = 72.8 bits (177), Expect = 3e-12
Identities = 146/635 (22%), Positives = 219/635 (34%), Gaps = 97/635 (15%)
Query: 565 IQTNPIPTHLSLVDSAQASPMPVDSVEADPTAV----GPVLA-----GPV---------- 605
+ P T S V SA +PV S + V GPV+ GPV
Sbjct: 448 VPVTPADTPGSPVTSADGPVVPVTSADIPLVPVTPPDGPVVPVTSADGPVAPVSSADGPV 507
Query: 606 ----PVDPGLVDLASTSSELVEPLPAEPVLINPVLADSAAV-----DPAVVPISDNLPPV 656
P D + + + +V PA+ +++ A+S A+ D +VP++ PV
Sbjct: 508 VPVTPADSPFIPVTTADDLIVPVTPADSPVLSVTPAESPAIPVTPADSPIVPVTPANGPV 567
Query: 657 DAVPSGPA------PVDLALVDPVPND-----LTPVD-PVL---------VKSRPTDPRR 695
V S + P D +V P D +TP D PVL V P D
Sbjct: 568 VPVTSADSPFVPVIPADGPVVPVTPADSPVVPVTPADSPVLSVTLADSPAVPVTPADSPV 627
Query: 696 GAVSSALGGSAPQLLVESESL------DPPKTIIPEVKEVVDSLKIESGTSATTHEARP- 748
V+ A G P +S + DP ++ P + + +S T RP
Sbjct: 628 VPVTPADGPVVPVASADSPFVPVTPADDPIVSVTPAESPAIPVTQADSPVVPVTSADRPV 687
Query: 749 RPLSLSEYRRRRQQRQAE-----TEERSPQPPTGKWPSLPETPTGLADIPCLVIPP---- 799
P++ ++ R + T +P P P P AD P + + P
Sbjct: 688 IPVTTADGRIVPVTAAGDPIVPVTPADTPGSPVTSADG-PVVPVTSADSPFVPVTPPDGP 746
Query: 800 --------APAKKTALQRSPETPLEICLVPVGPSPASPSPEPPVSKPVASSPTEQVPSQE 851
P + P P+ PV P ++ P PV+ + P V S +
Sbjct: 747 VVPVTSADGPVAPVSSADGPVVPVTSADGPVAPVSSADGPVVPVTPADTNGPAVPVTSAD 806
Query: 852 MPLLARPSPPVQSVSPAVPTPPSMSAALPFPAGGLGMPPSLPPPPLQPPSLPLSMGPVLP 911
P + P + + SP VP P+ +P P + P +P GPV+
Sbjct: 807 SPFV----PVIPADSPVVPVTPADDPIVPVTPADSSFVPVISADSPFVPVIPAD-GPVVV 861
Query: 912 DPFTHYAPLPSWPCYPHVSPSGYPCLPPPPTVPL-VSGTPGAYAVPP-TCSVPWAPPPAP 969
D T +P +P V+ P VPL + +P PP VP P P
Sbjct: 862 DSSTDVLVVPVFP----VNCILVPAFADETVVPLNPADSPVIPVTPPDDLVVPVTPTDCP 917
Query: 970 VSPYSST-CTYGPLGWGPGPQHAPFWSTVPPPPLPPAS--IGRAVPQPKMESRGTPAGPP 1026
V+P +S C P+ P + P P PA I P TPA P
Sbjct: 918 VAPVTSADCPVVPVTPADSPADPVTAADGPVVPFTPADDPIVPVTPADSPVVSVTPADGP 977
Query: 1027 ENVLPLSMAPPLSLGLPGHGAPQTEPTKVEVKPVPASPHPKHKVSALVQSPQMKALACVS 1086
V+P++ A + + P T E +P + V V S +
Sbjct: 978 --VVPVASADSPFVPVTPADDPIVSVTPAESPAIPVTQADSPVVP--VTSADRPVSPVTT 1033
Query: 1087 AEG-VTVEEPASERLKPETQETRPREKPPLPATKA 1120
A+G + A + + P T P + P P T A
Sbjct: 1034 ADGRIVPVTAAGDPIVPVT----PADTPGSPVTSA 1064
Score = 71.6 bits (174), Expect = 6e-12
Identities = 167/713 (23%), Positives = 245/713 (34%), Gaps = 107/713 (15%)
Query: 559 PKLADTIQTNPIPTHLSLVDSAQASPMPVDSVEADPTAVGPVLAGPVPVDPG---LVDLA 615
P + P + + V A + + V ++ V P + VPV P +V +A
Sbjct: 582 PADGPVVPVTPADSPVVPVTPADSPVLSVTLADSPAVPVTPADSPVVPVTPADGPVVPVA 641
Query: 616 STSSELVEPLPAEPVLINPVLADSAAV-----DPAVVPISDNLPPVDAVPSGPAPVDLAL 670
S S V PA+ +++ A+S A+ D VVP++ PV +P A +
Sbjct: 642 SADSPFVPVTPADDPIVSVTPAESPAIPVTQADSPVVPVTSADRPV--IPVTTADGRIVP 699
Query: 671 VDPVPNDLTPVDPVLVKSRPTDPRRGAVSSALGGSAPQLLVESESLDPPKTIIPEVKEVV 730
V + + PV P P G V +P V D P + V
Sbjct: 700 VTAAGDPIVPVTPADTPGSPVTSADGPVVPVTSADSP--FVPVTPPDGPVVPVTSADGPV 757
Query: 731 DSLKIESG--TSATTHEARPRPLSLSEYRRRRQQRQAETEERSPQPPTGKWPSLPETPTG 788
+ G T+ + P+S + + P T + P P
Sbjct: 758 APVSSADGPVVPVTSADGPVAPVS--------------SADGPVVPVTPADTNGPAVPVT 803
Query: 789 LADIPCLVIPPAPAKKTALQRSPETPLEICLVPVGPSPASPSPEPPVSK-----PVASSP 843
AD P + + PA + P TP + +VPV +PA S P +S PV +
Sbjct: 804 SADSPFVPVIPADSPVV-----PVTPADDPIVPV--TPADSSFVPVISADSPFVPVIPAD 856
Query: 844 TEQVPSQEMPLLARPSPPVQSV-------SPAVPTPPSMSAALPF-PAGGLGMPPSLPPP 895
V +L P PV + VP P+ S +P P L +P +
Sbjct: 857 GPVVVDSSTDVLVVPVFPVNCILVPAFADETVVPLNPADSPVIPVTPPDDLVVPVTPTDC 916
Query: 896 PLQP------PSLPLSMGPVLPDPFTHYAPLPSWPCYPHVSPSGYPCLP-PPPTVPLVSG 948
P+ P P +P++ DP T P P +P+ P +P P P+VS
Sbjct: 917 PVAPVTSADCPVVPVTPADSPADPVT----AADGPVVP-FTPADDPIVPVTPADSPVVSV 971
Query: 949 TPGAYAVPPTCSV--PWAP------PPAPVSPYSSTCTYGPLGWGPGPQHAPFWSTVPPP 1000
TP V P S P+ P P V+P S P+ P + P
Sbjct: 972 TPADGPVVPVASADSPFVPVTPADDPIVSVTPAESPAI--PVTQADSPVVPVTSADRPVS 1029
Query: 1001 PLPPASIGRAVPQPKMESRGTPAGPPENVLPLSMAPPLSLGLPGHGAPQTEPTKVEVKPV 1060
P+ A GR VP T AG P ++P++ A + P T + V
Sbjct: 1030 PVTTAD-GRIVPV-------TAAGDP--IVPVTPADTPGSPVTSADGPVVPVTSADSPFV 1079
Query: 1061 PASPHPKHKVS--------ALVQSPQMKALACVSAEGVTVEEPASERLKPETQETRPREK 1112
P +P V A V S + SA+G P S P T P +
Sbjct: 1080 PVTPPDGPVVPVTSADGPVAPVSSADGPVVPVTSADGPVA--PVSSADGPVVPVT-PADS 1136
Query: 1113 PPLPATKAVPTPRQSTVPKLPAVHPARLRKLSFLP-TPRTQGSEDVVQAFISEIGIEASD 1171
P +P T T VP PA P L+ P P T V+ + +
Sbjct: 1137 PFIPVT----TADDPIVPVTPADSPVLSVTLADSPVVPVTPADSPVIPVPPANGPV---- 1188
Query: 1172 LSSLLEQFEKSEAKKECPPPAPADSLAVGNSGGVDIPQEKRPLDRLQAPELAN 1224
S A P PAD L V +S + P D + P+LA+
Sbjct: 1189 -------VPVSSADSPFVPVIPADGLVVLDSSTDVLVVPVSPTDGILVPDLAD 1234
Score = 71.2 bits (173), Expect = 8e-12
Identities = 190/793 (23%), Positives = 279/793 (35%), Gaps = 121/793 (15%)
Query: 568 NPIPTHLSLVDSAQASPMPVDSVEADPTAVGPVLAGPVPVDPGLVDLASTSSELVEPL-P 626
+P+ +++V S +PV T G +P D GLV L S++ LV P+ P
Sbjct: 23 SPVVLPITVVVQTDGSVVPV-------TRAGSPFVPVIPAD-GLVVLDSSTDVLVVPVFP 74
Query: 627 AEPVLI-----NPVLADSAAVDPAVVPISDNLPPVDAVPSGPAPVDLALVDPVPNDLTPV 681
A+ +L+ NPV+ + A D V P++ PV V S PV + P N + PV
Sbjct: 75 ADGILVPDFADNPVVPVTPA-DDLVFPVTPADSPVIPVTSADDPV--VPITPADNPVVPV 131
Query: 682 DPV---LVKSRPTDPRRGAVSSALGGSAPQLLVESESL------DPPKTIIPEVKEVVDS 732
++ P D V+SA G P +S P + P +
Sbjct: 132 TSANGPVIPVTPADSPVFPVASADGPVVPVTPADSPVFPVTPADSPLFPVTPADSPLFPV 191
Query: 733 LKIESGTSATTHEARP----RPLSLSEYRRRRQQRQAETEERSPQPPTGKWPS----LPE 784
+S T P P + + T + P P+ +P
Sbjct: 192 TPADSAAIPVTPADGPVVHVTPANGTVVPVTPADSPVVTVASTDSPVVPVTPADDPIVPV 251
Query: 785 TPTGLADIPCL-----VIPPAPA-------KKTALQRSPETPLEICLVPVGPSPASPSPE 832
TP + +P + +P PA T + P P+ LVP
Sbjct: 252 TPADSSFVPVISADSPFVPVIPADGPVVVDSSTDVLVVPVFPVNCILVPAFADETIXXXX 311
Query: 833 PP----VSKPVASSPTEQVPSQEMPLLARPSPPVQSVSPAVPTPPSMSAALP-FPAGGLG 887
VS A P V + P+L+ + SP VP P+ S +P PA G
Sbjct: 312 XXXSLVVSVTTADDPIVPVTPADSPVLS----VTLADSPVVPVTPADSPFVPAIPADG-- 365
Query: 888 MPPSLPPPPLQPPSLPLSM--GPVL-----PDPFTHYAPLPSWPCYPHVSPSGYPCLP-- 938
P +P P P +P++ GPV+ PF P V+P+ P +P
Sbjct: 366 --PVVPVTPADSPVVPVTPADGPVVSVASADSPFVPVTPADD--PIVSVTPADSPVVPVT 421
Query: 939 --PPPTVPLVSGTPGAYAVPPTCS----VPWAPPPAPVSPYSSTCTYGPLGWGPGPQHAP 992
P +P+ T VP T + VP P P SP +S GP+
Sbjct: 422 SADSPLIPVT--TADGRVVPVTAAGDPIVPVTPADTPGSPVTS--ADGPVVPVTSADIPL 477
Query: 993 FWSTVPPPPLPPASIGRAVPQPKMESRG-----TPAGPPENVLPLSMAPPLSLGLPGHGA 1047
T P P+ P + P + G TPA P +P++ A L + + +
Sbjct: 478 VPVTPPDGPVVPVTSADGPVAPVSSADGPVVPVTPADSP--FIPVTTADDLIVPVTPADS 535
Query: 1048 PQTEPTKVEVKPVPASP--------HPKHKVSALVQSPQMKALACVSAEGVTVE-EPASE 1098
P T E +P +P P + V S + + A+G V PA
Sbjct: 536 PVLSVTPAESPAIPVTPADSPIVPVTPANGPVVPVTSADSPFVPVIPADGPVVPVTPADS 595
Query: 1099 RLKPETQETRPREKPPLPATKAVP-TPRQS-TVPKLPA---VHPARLRKLSFLP-TPRTQ 1152
+ P T P L + AVP TP S VP PA V P F+P TP
Sbjct: 596 PVVPVTPADSPVLSVTLADSPAVPVTPADSPVVPVTPADGPVVPVASADSPFVPVTPADD 655
Query: 1153 GSEDVVQAFISEIGIEASDLSSLLEQFEKSEAKKECPPPAPADSLAVGNSGGVDIPQEKR 1212
V A I + +D + + A + P AD V + D
Sbjct: 656 PIVSVTPAESPAIPVTQADSPVV----PVTSADRPVIPVTTADGRIVPVTAAGDPIVPVT 711
Query: 1213 PLDRLQAPELANVAGLTP---------PATPPHQLWKPLAAVSLLAKAKSPKSTAQEGTL 1263
P D +P + + P P TPP P+ V+ +P S+A +G +
Sbjct: 712 PADTPGSPVTSADGPVVPVTSADSPFVPVTPPD---GPVVPVTSADGPVAPVSSA-DGPV 767
Query: 1264 KPEGVTEAKHPAA 1276
P VT A P A
Sbjct: 768 VP--VTSADGPVA 778
Score = 71.2 bits (173), Expect = 8e-12
Identities = 145/573 (25%), Positives = 207/573 (36%), Gaps = 77/573 (13%)
Query: 611 LVDLASTSSELVEPLPAEPVLINPVLADSAAVDPAVVPISDNLPPVDAVPS-GPAPVDLA 669
+V + + +V PA+ +PVL+ + A P V + P V A+P+ GP
Sbjct: 317 VVSVTTADDPIVPVTPAD----SPVLSVTLADSPVVPVTPADSPFVPAIPADGPV----- 367
Query: 670 LVDPVPNDLTPVDPVLVKSRPTDPRRGAVSSALGGSAPQLLVESESLDPPKTIIPEVKEV 729
VP +TP D +V P P G V S +P + V + + DP ++ P V
Sbjct: 368 ----VP--VTPADSPVV---PVTPADGPVVSVASADSPFVPV-TPADDPIVSVTPADSPV 417
Query: 730 VDSLKIESG-TSATTHEARPRPLSLSEYRRRRQQRQAETEERSPQPPTGKWPSLPETPTG 788
V +S TT + R P++ + T +P P P P
Sbjct: 418 VPVTSADSPLIPVTTADGRVVPVTAA-----GDPIVPVTPADTPGSPVTSADG-PVVPVT 471
Query: 789 LADIPCLVI--PPAPAKKTALQRSPETPLEICLVPVGPSPASPSPEPPVSK------PV- 839
ADIP + + P P P P+ PV P + SP PV+ PV
Sbjct: 472 SADIPLVPVTPPDGPVVPVTSADGPVAPVSSADGPVVPVTPADSPFIPVTTADDLIVPVT 531
Query: 840 -ASSPTEQVPSQEMPLL--ARPSPPVQSVSPA-VPTPPSMSAALPF----PAGGLGM--- 888
A SP V E P + P+ V+PA P P SA PF PA G +
Sbjct: 532 PADSPVLSVTPAESPAIPVTPADSPIVPVTPANGPVVPVTSADSPFVPVIPADGPVVPVT 591
Query: 889 PPSLPPPPLQPPSLPLSMGPVLPDPFTHYAPLPSWPCYPHVSPSGYPCLP---------- 938
P P P+ P P+ + P P S P P V+P+ P +P
Sbjct: 592 PADSPVVPVTPADSPVLSVTLADSPAVPVTPADS-PVVP-VTPADGPVVPVASADSPFVP 649
Query: 939 -PPPTVPLVSGTPG-AYAVPPTCS----VPWAPPPAPVSPYSSTCTYGPLGWGPGPQHAP 992
P P+VS TP + A+P T + VP PV P ++ G P
Sbjct: 650 VTPADDPIVSVTPAESPAIPVTQADSPVVPVTSADRPVIPVTTADGRIVPVTAAGDPIVP 709
Query: 993 FWSTVPPPPLPPASIGRAVPQPKMESRGTPAGPPEN-VLPLSMAPPLSLGLPGHGAPQTE 1051
P ++ G VP +S P PP+ V+P++ A + P
Sbjct: 710 VTPADTPGSPVTSADGPVVPVTSADSPFVPVTPPDGPVVPVTSADGPVAPVSSADGPVVP 769
Query: 1052 PTKVEVKPVPASPHPKHKVSALVQSPQMKALACVSAEGVTVEE-PASERLKPETQETRPR 1110
T + P S V A+ SA+ V PA + P T P
Sbjct: 770 VTSADGPVAPVSSADGPVVPVTPADTNGPAVPVTSADSPFVPVIPADSPVVPVT----PA 825
Query: 1111 EKPPLPATKA------VPTPRQSTVPKLPAVHP 1137
+ P +P T A V + VP +PA P
Sbjct: 826 DDPIVPVTPADSSFVPVISADSPFVPVIPADGP 858
Score = 69.7 bits (169), Expect = 2e-11
Identities = 192/787 (24%), Positives = 290/787 (36%), Gaps = 125/787 (15%)
Query: 545 GQSSPAKEGPLDLYPKLADTI-QTNPIPTHLSLVDSAQASPMPVDSVEADPTAVGPVLAG 603
G + +GP+ D I P T S V SA +PV + + GP++
Sbjct: 1416 GSPVTSADGPVVPVTPAGDPIVPVTPADTPGSPVTSADGPVVPVTTPD------GPLV-- 1467
Query: 604 PV-PVDPGLVDLASTSSELVEPLPAEPVLINPVLADSAAVDPAVVPISDNLPPVDAVPSG 662
PV P D +V + S +V PA+ +P + + A DP +VP++ PV VP
Sbjct: 1468 PVSPPDGPVVPVTSADGPVVPVTPAD----SPFIPVTTADDP-IVPVTPADSPV--VPVT 1520
Query: 663 PAPVDLALVDPVPNDLTPVDPVLVKSRPTDPRRGAVSSALGGSAPQLLVESESLDPPKTI 722
PA + + V P + V P P G V AL S L+V D +
Sbjct: 1521 PADIPVVPVTPANGPVIHVTSADCPFVPVIPADGLV--ALDSSTDVLVVPVSPTDG--VL 1576
Query: 723 IPEVKE--VVDSLKIESGT-SATTHEARPRPLSLSEYRRRRQQRQAETEERSPQPPT--G 777
+P++ + VV +S T ++ P++L++ T P P
Sbjct: 1577 VPDLADDPVVSVTIADSPVIPVTPADSTVVPVTLAD-----GPVVPVTSVDIPVVPVTPA 1631
Query: 778 KWPSLPETPTGLADIPCLVIPPA-----PAKKTALQRSPETPLEICLVPVGPS-----PA 827
P P TP D P + + PA P P TP + +VPV P+ P
Sbjct: 1632 NGPVAPVTPV---DDPVVSVNPADGSVVPVTSADCPVVPVTPADGLVVPVTPADSPIVPV 1688
Query: 828 SPSPEPPVSKPVASSPTEQVPSQEMPLLA-------RPSPPVQSV-SPAVPTPPSMSAAL 879
+P+ P V A SP V + P++ P PV S P VP + S +
Sbjct: 1689 TPADSPVVLVTSADSPVIPVTPADSPVVPVTSADTDSPGSPVTSADGPVVPVTSADSLPV 1748
Query: 880 PF-PAGGLGMPPSLPPPPLQP------PSLPLSM--GPVLP-----DPFTHYAPLPSWPC 925
P PA G +P + P+ P P +P++ PV+P DP P S P
Sbjct: 1749 PVTPADGPVVPVTSADGPVAPVSSADGPVVPVTPADSPVVPVTTADDPTVPVTPADS-PV 1807
Query: 926 YPHVSPSGYPCLP----PPPTVPL-------------------VSGTPGA----YAVPPT 958
P V P+ P +P P VP+ VS T G A P
Sbjct: 1808 VP-VPPANGPIVPVTSADSPFVPVIPADGLVVLDSSTDVLVVPVSPTDGILVPDLADDPV 1866
Query: 959 CSVPWAPPPA-PVSPYSSTCTYGPLGWGPGPQHAPFWST-VPPPPLPPASIGRAVPQPKM 1016
SV A P PV+P S GP P S P P+ PA +P +
Sbjct: 1867 VSVTIADSPVIPVTPADSPVVLVTPADGP---VVPVTSVDNPVVPVTPAD-NPVIPVTPV 1922
Query: 1017 ESRGTPAGPPEN-VLPLSMAPPLSLGLPGHGAPQTEPTKVEVKPVPASPHPKHKVSALVQ 1075
+ P P ++ ++P++ A + + +P T + +P + V V
Sbjct: 1923 DDPVVPVTPADDPIVPVTSADSPIVSVTPADSPVFPVTPADSPVIPVASADSPLVP--VT 1980
Query: 1076 SPQMKALACVSAEGVTVE-EPASERLKPETQETRPREKPPLPATKA----VPTPRQST-V 1129
M + + A+G + PA P T P + P +P T A +P S V
Sbjct: 1981 PADMVVVPVIPADGPVIPVTPAESPAIPVT----PTDSPVVPVTSADSPVIPVTADSPFV 2036
Query: 1130 PKLPAVHPA-RLRKLSFLPTPRTQGSEDVVQAFISEIG-IEASDLSSLLEQFEKSEAKKE 1187
P PA P + L P T VV + + + + +S ++ + A
Sbjct: 2037 PVTPADSPVIPVTPPDDLVVPVTPIDCPVVPVTLVDCPVVSVTPANSPVDPV--TPADGP 2094
Query: 1188 CPPPAPADSLAVGNSGGVDIPQEKRPLDRLQAPELANVAGLTPPATPPHQLWKPLAAVSL 1247
P PADS + + D+ P D L + +TP +P + + V
Sbjct: 2095 VVPVTPADSPVIPVTPADDLIVPVTPADSL-------IVSVTPADSPVVPVTPADSPVIS 2147
Query: 1248 LAKAKSP 1254
+A A SP
Sbjct: 2148 VASADSP 2154
Score = 62.4 bits (150), Expect = 4e-09
Identities = 144/635 (22%), Positives = 207/635 (32%), Gaps = 115/635 (18%)
Query: 548 SPAKEGPLDLYPKLADTIQTNPIPTHLSLVDSAQASPMPVDSVEADPTAVGPVLAGP--- 604
SP P P +AD++ + + DS V DPT GPV P
Sbjct: 3213 SPVVPDPSSDGPVVADSLDDDGLVPVTPADDSVVPDSPANGLVVPDPTTDGPVAPDPSVD 3272
Query: 605 ---VPVDPGLVDLASTSSELVEPLPAEPVLINP----VLADSAAVDPAVVPISDNLPPVD 657
VPV P D + S L + V + P V++DS P V +S N P +
Sbjct: 3273 GPVVPVTPA--DAPTVSVTLAD---CPDVTVTPPDGLVVSDSKRGGPVVTGLSTNDPVIT 3327
Query: 658 AVPSGPAPVDLALVDPVPNDLTPVDPVLVKSRPTDPRRGAVSSALGGSAPQLLVESES-- 715
A P+ + V V P + PV P P +P VS +V S+
Sbjct: 3328 ATPADFSDV---TVTPADFEDVPVTPANCPDVPVNPESPVVSDLAVDFLVVPVVPSDDLV 3384
Query: 716 -LDPPKTI----IPEVKEVVDSLKIESGTSATTHEARPRPLSLSEYRRRRQQRQAETEER 770
L+PP + P +V S I + T+AT + +S
Sbjct: 3385 VLEPPDKVPVVPDPISNGLVVSDPITNNTAATDPSVDGSVVPVS---------------- 3428
Query: 771 SPQPPTGKWPSLPETPTGLADIPCLVIPPA--PAKKTALQRSPETPLEICLVPVGPSPAS 828
P G P P LAD P + I PA + R+ + + + P +
Sbjct: 3429 ---PADG-----PVAPVTLADCPDVTITPADDSVVSDSKIRAEFEDVPVTIADCPNVPVN 3480
Query: 829 PSPEPPVSKPVASSPTEQVPSQEMPLLARPSPPVQSVSPAVPTPPSMSAALPFPAGGLGM 888
P P VS P +P + L P PP + P VP P + S +
Sbjct: 3481 PKSGPVVSDLAVDCPVVPIPPPDD--LVAPEPPDE--VPVVPDPITDSLVV--------- 3527
Query: 889 PPSLPPPPLQPPSLPLSMGPVLPDPFTHYAPLPSWPCYPHVSPSGYPCLPPPPTVPLVSG 948
S P++ GPV DP +P VSPSG L V ++
Sbjct: 3528 ------------SDPMTDGPVASDPSIDGIVVPV------VSPSGLLVLDSVADVSILPD 3569
Query: 949 TPGAYAVPPT-----CSVPWAPPPAPVSPYSSTCTYGPLGWGPGPQHAPFWSTVPPPPLP 1003
T V P VP + P PV P T + L P
Sbjct: 3570 TSADVPVTPVTLADGSVVPDSAPDCPVVPVLPTDGFVVLDLLVDGVVVP----------N 3619
Query: 1004 PASIGRAVPQPKMESRGTPAGPPENVLPLSMAPPLSLGLPGHGAPQTEPTKVEVKPVPAS 1063
PA +G VP P + P+++ + P P P T+ + PV
Sbjct: 3620 PADVGPVVPDPTTDG-------PDSIKDFPLVPD-----PWPDCPVVPVTRTD-GPVVLD 3666
Query: 1064 PHPKHKVSALVQSPQMKALACVSAEGVTVEEPASERLKPETQETRPREKPPLPATKAVPT 1123
V + AL + V + + P+ P L VP
Sbjct: 3667 SSADGVVVPVTPGDDSVALVTPTDNLVVPDLTTDGPVVPDPSADGPVVLVSLADDLLVPN 3726
Query: 1124 P--RQSTVPKLPAVHPARLRKLS---FLPTPRTQG 1153
P + + VP A +P L ++ +P P G
Sbjct: 3727 PPVKDTVVPNSVADNPVALDPVTDCPLVPEPSANG 3761
Score = 58.2 bits (139), Expect = 7e-08
Identities = 198/873 (22%), Positives = 291/873 (33%), Gaps = 170/873 (19%)
Query: 614 LASTSSELVEPLPAEPVLINP----VLADSAAV--DPAVVPISD-NLPPVDAVPSGPAPV 666
+A ++E+ + LP+ V + P VL + V D +VVP++ P V +P+ V
Sbjct: 1 MAPVATEIKKYLPSGAVTLLPGSPVVLPITVVVQTDGSVVPVTRAGSPFVPVIPADGLVV 60
Query: 667 DLALVDPVPNDLTPVDPVLVKSR------PTDPRRGAVSSALGGSAPQLLVESESLDPPK 720
+ D + + P D +LV P P V +P + V S DP
Sbjct: 61 LDSSTDVLVVPVFPADGILVPDFADNPVVPVTPADDLVFPVTPADSPVIPVTSAD-DPVV 119
Query: 721 TIIPEVKEVVDSLKIESGTSATTHEARPRPLSLSEYRRRRQQRQAETEERSPQPPTGK-- 778
I P VV T+ P++ ++ SP P
Sbjct: 120 PITPADNPVVP---------VTSANGPVIPVTPAD---------------SPVFPVASAD 155
Query: 779 WPSLPETPTGLADIPCLVIPPAPAKKTALQRSPETPLEICLVPVGPSPASPSPEPPVSKP 838
P +P TP AD P V P PA P TP + L PV P+ ++ P P P
Sbjct: 156 GPVVPVTP---ADSP--VFPVTPADSPLF---PVTPADSPLFPVTPADSAAIPVTPADGP 207
Query: 839 V---------------ASSPTEQVPSQEMPLLARPSPPVQSVSPAVPTPPSMSAALPFPA 883
V A SP V S + P++ P + P VP P+ S+ +P +
Sbjct: 208 VVHVTPANGTVVPVTPADSPVVTVASTDSPVV----PVTPADDPIVPVTPADSSFVPVIS 263
Query: 884 GGLGMPPSLPP--PPLQPPSLPLSMGPVLP------------------------------ 911
P +P P + S + + PV P
Sbjct: 264 ADSPFVPVIPADGPVVVDSSTDVLVVPVFPVNCILVPAFADETIXXXXXXXSLVVSVTTA 323
Query: 912 -DPFTHYAP---------LPSWPCYPHVSPSGYPCLPP-PPTVPLVSGTPGAYAVPPTCS 960
DP P L P P V+P+ P +P P P+V TP V
Sbjct: 324 DDPIVPVTPADSPVLSVTLADSPVVP-VTPADSPFVPAIPADGPVVPVTPADSPV----- 377
Query: 961 VPWAPPPAP-VSPYSSTCTYGPLGWGPGPQHAPFWSTVP--PPPLPPASI-GRAVPQPKM 1016
VP P P VS S+ + P+ P P S P P +P S +P
Sbjct: 378 VPVTPADGPVVSVASADSPFVPV----TPADDPIVSVTPADSPVVPVTSADSPLIPVTTA 433
Query: 1017 ESRGTP---AGPPENVLPLSMAPPLSLGLPGHGAPQTEPTKVEVKPVPASPHPKHKVSAL 1073
+ R P AG P ++P++ A + P T ++ VP +P V
Sbjct: 434 DGRVVPVTAAGDP--IVPVTPADTPGSPVTSADGPVVPVTSADIPLVPVTPPDGPVVP-- 489
Query: 1074 VQSPQMKALACVSAEGVTVE-EPASERLKPETQ----------------ETRPREKPPLP 1116
V S SA+G V PA P T P E P +P
Sbjct: 490 VTSADGPVAPVSSADGPVVPVTPADSPFIPVTTADDLIVPVTPADSPVLSVTPAESPAIP 549
Query: 1117 ATKAVPTPRQSTVPKLPAVHPARLRKLSFLPTPRTQGS-EDVVQAFISEIGIEASDLSSL 1175
T A +P P V P F+P G V A + + +D L
Sbjct: 550 VTPA-DSPIVPVTPANGPVVPVTSADSPFVPVIPADGPVVPVTPADSPVVPVTPADSPVL 608
Query: 1176 LEQFEKSEAKKECPPPAPADSLAVGNSGGVDIPQEKRPLDRLQAPE--LANVAGLTPPAT 1233
S A P +P + + V + P + + + +V PA
Sbjct: 609 SVTLADSPAVPVTPADSPVVPVTPADGPVVPVASADSPFVPVTPADDPIVSVTPAESPAI 668
Query: 1234 PPHQLWKPLAAVSLLAKAKSPKSTAQEGTLKPEGVTEAKHPAAVRLQEGVHGP------- 1286
P Q P+ V+ + P +TA +G + P VT A P G
Sbjct: 669 PVTQADSPVVPVTSADRPVIPVTTA-DGRIVP--VTAAGDPIVPVTPADTPGSPVTSADG 725
Query: 1287 SRVHVGSGDHDYCVRSRTPPKKMPALVIPEVGSRWNVKRHQDITIKPVLSL-GPAAPPPP 1345
V V S D + TPP P + + D + PV S GP AP
Sbjct: 726 PVVPVTSADSPFV--PVTPPDG-PVVPVTSADGPVAPVSSADGPVVPVTSADGPVAP--- 779
Query: 1346 CIAASREPLDHRTSSEQADPSAPCLAPSSLLSP 1378
++++ P+ T ++ P+ P + S P
Sbjct: 780 -VSSADGPVVPVTPADTNGPAVPVTSADSPFVP 811
Score = 50.4 bits (119), Expect = 1e-05
Identities = 137/625 (21%), Positives = 211/625 (33%), Gaps = 90/625 (14%)
Query: 547 SSPAKEGPLDLYPKLADTIQTNPIPTHLSLVDSAQASPMPVDSVEADPTAVGPVLAGPVP 606
S+P +GP+ P D + P + S+ + V AD T V P + GPV
Sbjct: 2949 STPVTDGPVVTDPA-TDGLMVPVTPANGSVAPVTLSEYPDVTVTPADGTVVSPTIGGPVV 3007
Query: 607 VDPGL---VDLASTSSELVEPLPAEPVLINPVLADSAAVDPAVVPISDNLPPVDAVPSGP 663
DP V T+ L+ P P+L PV+ + P I + P V P+
Sbjct: 3008 PDPSADSSVVSNPTTDGLIVP---NPLLAGPVVPVTPTDGPLAPVILADCPDVTVTPAD- 3063
Query: 664 APVDLALVDPVPNDLTPVDPVLVKSRPT--DP------RRGAVSSALGGSAPQLLVESES 715
PV A P P LV S PT DP +G VS+ A ++ ++
Sbjct: 3064 GPVVCAFTTGGPVFPDPTAEGLVVSNPTVDDPVVTNPSTKGLVSATPADCADVPVIPADC 3123
Query: 716 LDPPKTIIPE--VKEVVDSLKIESGTSATTHEARPRPLSLSEYRRRRQQRQAETEERSPQ 773
D ++ + V + + S + A P + + +
Sbjct: 3124 PDVLVNLVNDSVVPDFTADWTVVSVSPPDDLVAPDPPDEVPVVLVPITDGPVVPDLTTDG 3183
Query: 774 PPTGKWPS-LPETPTGLADIPCLVIPPAPAKKTALQRSPETPL------EICLVPVGPSP 826
P+ P P L D P + + PA + S + P+ + LVPV P+
Sbjct: 3184 LVVSVTPAGAPVVPVFLTDCPDVTVTPADSPVVP-DPSSDGPVVADSLDDDGLVPVTPAD 3242
Query: 827 ASPSPEPPVSKPVASSPTEQVPSQEMPLLARPSPPVQSVSPAVPTPPSMSAALPFPAGGL 886
S P+ P + V PT P P P V P VP P A P + L
Sbjct: 3243 DSVVPDSPANGLVVPDPTTDGP-------VAPDPSVD--GPVVPVTP---ADAPTVSVTL 3290
Query: 887 GMPPSLPPPPLQPPSLPLS----MGPVL-------------PDPFTHYAPLPSWPCYPHV 929
P + P P L +S GPV+ P F+ P+ V
Sbjct: 3291 ADCPDVTVTP--PDGLVVSDSKRGGPVVTGLSTNDPVITATPADFSDVTVTPADFEDVPV 3348
Query: 930 SPSGYPCLPPPPTVPLVSGTPGAYAVPPTCSVPWAPPPAPVSPYSSTCTYGPLGWGPGPQ 989
+P+ P +P P P+VS + V PV P P P
Sbjct: 3349 TPANCPDVPVNPESPVVSDLAVDFLV------------VPVVPSDDLVVLEP------PD 3390
Query: 990 HAPFWSTVPPPPL-------PPASIGRAVPQPKMESRGTPAGPPEN-VLPLSMA--PPLS 1039
P V P P+ P + A P ++ P P + V P+++A P ++
Sbjct: 3391 KVP----VVPDPISNGLVVSDPITNNTAATDPSVDGSVVPVSPADGPVAPVTLADCPDVT 3446
Query: 1040 LGLPGHGAPQTEPTKVEVKPVPASPHPKHKVSALVQSPQMKALACVSAEGVTVEEPASER 1099
+ + E + VP + V +S + + V V + P +
Sbjct: 3447 ITPADDSVVSDSKIRAEFEDVPVTIADCPNVPVNPKSGPVVSDLAVDCPVVPI-PPPDDL 3505
Query: 1100 LKPETQETRPREKPPLPATKAVPTP 1124
+ PE + P P+ + V P
Sbjct: 3506 VAPEPPDEVPVVPDPITDSLVVSDP 3530
Score = 40.8 bits (94), Expect = 0.011
Identities = 103/429 (24%), Positives = 148/429 (34%), Gaps = 105/429 (24%)
Query: 561 LADTIQTNPIPTHLSLVDS----AQASPMPVDSVEADPTAVGPVLAGPVPVDPGLVDLAS 616
LAD P S+V A+ +PV + V P +GPV + DLA
Sbjct: 3439 LADCPDVTITPADDSVVSDSKIRAEFEDVPVTIADCPNVPVNPK-SGPV-----VSDLAV 3492
Query: 617 TSSELVEPLPAEPVLINPVLADSAAVDPAVVPISDNLPPVDAVPSGPAPVDLAL---VDP 673
V P+P L+ P D V P PI+D+L D + GP D ++ V P
Sbjct: 3493 DCP--VVPIPPPDDLVAPEPPDEVPVVPD--PITDSLVVSDPMTDGPVASDPSIDGIVVP 3548
Query: 674 V--PNDLTPVDPVLVKSR--------PTDPRRGAVSSALGGSAPQLLVESESLDPPKTII 723
V P+ L +D V S P P A S + SAP P ++
Sbjct: 3549 VVSPSGLLVLDSVADVSILPDTSADVPVTPVTLADGSVVPDSAPDC--------PVVPVL 3600
Query: 724 PEVKEVVDSLKIESGTSATTHEARPRPLSLSEYRRRRQQRQAETEERSPQPPTGKWPSLP 783
P VV L ++ P P + ++ + P P WP P
Sbjct: 3601 PTDGFVVLDLLVDGVVV-------PNPADVGPVVPDPTTDGPDSIKDFPLVPD-PWPDCP 3652
Query: 784 ETPTGLADIPCL--------VIPPAPAKKTALQRSPETPLEICLV----PVGPSPASPSP 831
P D P + V+P P + +P L + + PV P P++ P
Sbjct: 3653 VVPVTRTDGPVVLDSSADGVVVPVTPGDDSVALVTPTDNLVVPDLTTDGPVVPDPSADGP 3712
Query: 832 -------------EPPVS-----KPVASSPTEQVPSQEMPLLARPSPPVQSVSPAVPTPP 873
PPV VA +P P + PL+ PS
Sbjct: 3713 VVLVSLADDLLVPNPPVKDTVVPNSVADNPVALDPVTDCPLVPEPS-------------- 3758
Query: 874 SMSAALPFPAGGLGMPPSLPPPPLQPPSLPLSMGPVLPDPFTHYAPLPSWPCYPHVSPSG 933
A GL + SL P+ P P + PV+ +P T+ +P +S +G
Sbjct: 3759 ---------ANGLVVTDSLDEGPVVPD--PSADDPVVLNPETNGLVVPD------ISANG 3801
Query: 934 YPCLPPPPT 942
P +P PT
Sbjct: 3802 -PVVPDTPT 3809
Score = 33.5 bits (75), Expect = 1.8
Identities = 31/113 (27%), Positives = 48/113 (42%), Gaps = 10/113 (8%)
Query: 549 PAKEGPLDLYPKLADTIQTNPIPTHLSLVDSAQASPMPVDSVEADPTAVGPVLAGPVPVD 608
P+ +GP+ L D + NP P ++V + SV +P A+ PV P+ +
Sbjct: 3707 PSADGPVVLVSLADDLLVPNP-PVKDTVVPN---------SVADNPVALDPVTDCPLVPE 3756
Query: 609 PGLVDLASTSSELVEPLPAEPVLINPVLADSAAVDPAVVPISDNLPPVDAVPS 661
P L T S P+ +P +PV+ + V IS N P V P+
Sbjct: 3757 PSANGLVVTDSLDEGPVVPDPSADDPVVLNPETNGLVVPDISANGPVVPDTPT 3809
>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
Length = 1094
Score = 88.2 bits (217), Expect = 6e-17
Identities = 138/536 (25%), Positives = 205/536 (38%), Gaps = 107/536 (19%)
Query: 762 QRQAETEERSPQPPTGK-----WPSLPETPTGLADIPCL---VIPPAPAKKTALQRSPET 813
+R + ER+ P +G P+LP P GLA P PP P + T+L RSP
Sbjct: 568 RRPPRSPERTLSPSSGYSSQSGTPTLP--PKGLAGPPASPGKAQPPKPERVTSL-RSPGA 624
Query: 814 PLEICLVPVGPSPASPSPE----PPVSKPVASS----PTEQVPSQEMPLLARPSPPVQSV 865
+ L + S + P+P P + P+ P +VP+ P ++P P
Sbjct: 625 SVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSP-NPA 683
Query: 866 SPAVPTPPSMSAALPFPAGGLGMPPSLPPPPLQPPSLPLSMGPVLPDPFTHYAPLPSWPC 925
+PA+ P A +P P P PP P Q PL PV+ +P PS P
Sbjct: 684 APALAAP----AVVPGPVSTTDASPQSPPTP-QTTLTPLQESPVISKD---QSPPPSPP- 734
Query: 926 YPHVSPSGYPCLPPPPT----VPLVSGTPGAYAVPPTCSVPWAPPPAPVSPYSSTCTYGP 981
PS +P PPPPT V + + + A P W PPP P +P +
Sbjct: 735 -----PSYHP--PPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPP-APEEQDLSMAD 786
Query: 982 LGWGPGPQHAPFWSTVPPPPLPPASIGRAVPQPKMESRGTPAGPPENVLPLSMAPPLSLG 1041
P P+ A F+S P P P+ P++ S +PA + L + PP
Sbjct: 787 F---PPPEEA-FFSVASPEPAGPSG------SPELVS--SPAASSSSATALQIQPP---- 830
Query: 1042 LPGHGAPQTEPTKVEVKPVPASPHPKHKVSALVQSPQMKALACVSAEGVTVEEPASERLK 1101
G+P +P P PAS P H + + PQ + + C G E+ + +
Sbjct: 831 ----GSP--DPPPAPPAPAPASSAPGH----VAKLPQKEPVGCSKGGGPPREDVGAPLVT 880
Query: 1102 PET-QETRPREKPPLPATKAVPTPRQSTVPKLPAVHPARLRKLSFLPTPRTQGSEDVVQA 1160
P Q R R + A PTP + A + S +P P + G V+
Sbjct: 881 PSLLQMVRLRS---VGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAP-SSGLHAAVR- 935
Query: 1161 FISEIGIEASDLSSLLEQFEKSEAKKECPPPAPADSLAVGNSGGVDIPQEKRP------- 1213
+ + AS+ S + EA+ PP +PA + + S G Q +RP
Sbjct: 936 -LKACSLAASEGLSSAQPNGPPEAEPR-PPQSPASTASFIFSKGSRKLQLERPVSPETQA 993
Query: 1214 -LDRLQAPELANVA------------------------GLTPPATPPHQLWKPLAA 1244
L R EL +++ G+ PPA+P + +PL A
Sbjct: 994 DLQRNLVAELRSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSYPRAEPLTA 1049
Score = 65.5 bits (158), Expect = 4e-10
Identities = 163/714 (22%), Positives = 234/714 (32%), Gaps = 133/714 (18%)
Query: 691 TDPRRGAVSSALGGSAP-QLLVESESLDP---------PKTIIPEVKEVVDSLKIESGTS 740
T P AV GG+ P + L + S+ P P ++P +VV + T
Sbjct: 318 TRPMSLAVPGLTGGAGPAEPLSPAMSISPQATYLSKLIPHAVLPPTVDVVALGRCSLRTL 377
Query: 741 ATTHEARPRPLSLSEYRRRRQQRQAETEERSPQPPTGKWPSLPETPTGLADIPCLVIPPA 800
+ P S+ R + R P + W + T ++D L
Sbjct: 378 SRCSLHSASPASVRSLGRFSSVSSPQPRSRHPSSSSDTWSHSQSSDTIVSDGSTL----- 432
Query: 801 PAKKTALQRSPETPLEICLVPVGPSPASPSPEPPVSKPVASSPTEQVPSQ--------EM 852
+ K + PE+ V P S P +S T + S +
Sbjct: 433 -SSKGGSEGQPESSTASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSL 491
Query: 853 PLLARPSPPVQSVSPAVPTPPSMSAALPFPAGGLGMPPSLPPPPLQPPSLPLSMGPVLPD 912
L RP PP + T L P G LG+PP P Q P LP P
Sbjct: 492 RKLKRPPPPPRR------THSLHQRGLAVPDGPLGLPPK--PERKQQPQLPR------PP 537
Query: 913 PFTHYAPLPSWPCYPHVSPSGYPCLPPPPTVPLVSGTPGAYAVPPTCSVPWAPPPAPVSP 972
+ PC P+ + S P L +PG PP P + S
Sbjct: 538 TTGGSEGAGAAPCPPNPANSWVPGL-----------SPGGSRRPPRSPERTLSPSSGYSS 586
Query: 973 YSSTCTYGPLGWGPGPQHAPFWSTVPPPPL------PPASIGRAVPQPKMESRGTPAGPP 1026
S T T P G GP +P + P P P AS+ ++ + S + P
Sbjct: 587 QSGTPTLPPKGLA-GPPASPGKAQPPKPERVTSLRSPGASVSSSLTS--LCSSSSDPAPS 643
Query: 1027 ENVLPLSMAPPLSLG----LPGHGAPQTEPTKVEVKPVPASPHPKHKVSALVQSPQMKAL 1082
+ P + P LG +P H KV P P SP P S +P + A
Sbjct: 644 DRSGPQILTP---LGDRFVIPPH-------PKV---PAPFSPPPSKPRSPNPAAPALAAP 690
Query: 1083 ACVSAEGVTVEEPASERLKPETQETRPREKPPLPATKAVPTPRQSTVPKLPAVHPARLRK 1142
A V T + P+T T +E P + ++ P P+ HP
Sbjct: 691 AVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPP------PSYHP----- 739
Query: 1143 LSFLPTPRTQGSEDVVQAFISEIGIEASDLSSLLEQFEKSEAKKECPPPAPADSLAVGNS 1202
P P T+ E VV EA S E+ + PPPAP + +
Sbjct: 740 ----PPPPTKKPEVVV---------EAPSASETAEEPLQDPNWPPPPPPAPEEQ----DL 782
Query: 1203 GGVDIPQEKRPLDRLQAPELANVAGLTPPATPPHQLWKPLAAVSLLAKAKSPKSTAQEGT 1262
D P + + +PE A P+ P + P A+ S + + G+
Sbjct: 783 SMADFPPPEEAFFSVASPEPAG------PSGSPELVSSPAASSS----SATALQIQPPGS 832
Query: 1263 LKPEGVTEAKHPAAVRLQEGVHGPSRVHVGSGDHDYCVRSRTPPKK--MPALVIPEVGSR 1320
P A PA+ P + VG C + PP++ LV P +
Sbjct: 833 PDPPPAPPAPAPASSAPGHVAKLPQKEPVG------CSKGGGPPREDVGAPLVTPSLLQM 886
Query: 1321 WNVKRHQDITIKPVLSLGPAAPPPPCIAASREPLDHRTSSEQADPSAPCLAPSS 1374
++ P +LGP+AP P R L R S P APSS
Sbjct: 887 VRLRSVGAPGGAPTPALGPSAPQKPL----RRALSGRAS--------PVPAPSS 928
Score = 59.7 bits (143), Expect = 2e-08
Identities = 135/585 (23%), Positives = 187/585 (31%), Gaps = 116/585 (19%)
Query: 589 SVEADPTAVGPVLAGPVPVDPGLVDLASTSSELVEPLPAEPVLINPVLADSAAVDPAVVP 648
S PT LAGP P PG P +P + + + A+V ++
Sbjct: 586 SQSGTPTLPPKGLAGP-PASPGKAQ------------PPKPERVTSLRSPGASVSSSLTS 632
Query: 649 I-SDNLPPVDAVPSGPAPV----DLALVDPVPNDLTPVDPVLVKSRPTDPRRGAVSSALG 703
+ S + P + SGP + D ++ P P P P K R +P A+++
Sbjct: 633 LCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAV 692
Query: 704 GSAPQLLVESESLDPPK---TIIPEVKEVVDSLKIESGTSATTHEARPRPLSLSEYRRRR 760
P ++ PP T+ P + V S S P P +
Sbjct: 693 VPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVE 752
Query: 761 QQRQAETEERSPQPPTGKWPSLPETPTGLADIPCLVIPPAPAKKTALQRSPETPLEICLV 820
+ET E Q P WP P PPAP ++ P E
Sbjct: 753 APSASETAEEPLQDPN--WPPPP--------------PPAPEEQDLSMADFPPPEEAFFS 796
Query: 821 PVGPSPASPSPEPP-VSKPVASSPTEQVPSQEMPLLARPSPPVQSVSPAVPTPPSMSAAL 879
P PA PS P VS P ASS S + AL
Sbjct: 797 VASPEPAGPSGSPELVSSPAASS-------------------------------SSATAL 825
Query: 880 PFPAGGLGMPPSLPPPPLQPPSLPLSMGPVLPDPFTHYAPLPSWPCYPHVSPSGYPCLPP 939
G PP PP P S P H A LP G PP
Sbjct: 826 QIQPPGSPDPPPAPPAPAPASSAP-----------GHVAKLPQKEPVGCSKGGG----PP 870
Query: 940 PPTVPLVSGTPGAYAVPPTCSVPWAPPPAPVSPYSSTCTYGPLGWGPGPQHAPFWSTVPP 999
V TP + SV AP AP T GP + P
Sbjct: 871 REDVGAPLVTPSLLQMVRLRSV-GAPGGAP------TPALGP--------------SAPQ 909
Query: 1000 PPLPPASIGRAVPQPKMESRGTPAGPPENVLPLSMAPPLSLGLPGHGAPQTEPTKVEVKP 1059
PL A GRA P P S G A L+ + LS P +G P+ EP + P
Sbjct: 910 KPLRRALSGRASPVP-APSSGLHAAVRLKACSLAASEGLSSAQP-NGPPEAEPRPPQ-SP 966
Query: 1060 VPASPHPKHKVSALVQ-----SPQMKALACVSAEGVTVEEPASERLKPETQETRPREKPP 1114
+ K S +Q SP+ + A + V SE+ P+ + P+ PP
Sbjct: 967 ASTASFIFSKGSRKLQLERPVSPETQ--ADLQRNLVAELRSISEQRPPQAPKKSPKAPPP 1024
Query: 1115 LPATKAVPTPRQSTVPKLPAVHPARLRKLSFLPTPRTQGSEDVVQ 1159
+ +V P ++ P P P + LP + + ++ +
Sbjct: 1025 VARKPSVGVPPPAS-PSYPRAEPLTAPPTNGLPHTQDRTKRELAE 1068
Score = 50.8 bits (120), Expect = 1e-05
Identities = 177/781 (22%), Positives = 271/781 (34%), Gaps = 131/781 (16%)
Query: 140 SENLSPFDSIPDSELLVSPREGSSLHKLLTLSRTPPERDLITPVDPLGPSTGSSRGSGVE 199
+E LSP SI SP + + L KL+ + PP D++ LG + + S
Sbjct: 335 AEPLSPAMSI-------SP-QATYLSKLIPHAVLPPTVDVVA----LGRCSLRTL-SRCS 381
Query: 200 MSLPDPSWDFSPPSFLETSSPKLPSWRPPRSRPRWGQSPPPQQR-SDGEEEEEVASFSGQ 258
+ P+ S F SSP+ S P S W S SDG GQ
Sbjct: 382 LHSASPASVRSLGRFSSVSSPQPRSRHPSSSSDTWSHSQSSDTIVSDGSTLSSKGGSEGQ 441
Query: 259 ILAGELDNCVSSIPDFPMHLACPEEEDKATAAE-MAVPAAGDESISSLSELVRAMHPYCL 317
+ N V P P A A++ +++ ++G S S+S L + P
Sbjct: 442 PESSTASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVS-LRKLKRPPPP 500
Query: 318 PNLTHLASLEDELQEQPDDLTLPEGCVVLEIVGQAATAGDDLEIPVVVRQVSPG-PRPVL 376
P TH SL L +P+G + L P R+ P PRP
Sbjct: 501 PRRTH--SLHQR------GLAVPDGPLGLP--------------PKPERKQQPQLPRPPT 538
Query: 377 LDDSLETSSALQLLMPTLESETEAAVPKVTLCSEKEGLSLNSEEKLDSACLLKPREVVEP 436
S +A P + + VP ++ + + E L + +
Sbjct: 539 TGGSEGAGAA-----PCPPNPANSWVPGLSPGGSRRP-PRSPERTLSPSSGYSSQSGTPT 592
Query: 437 VVPKEPQNPPANAAPGSQRARKGRKKKSKEQPAACVEGYARRLRSSSRGQSTV---GTEV 493
+ PK PPA+ PG + K + S P A V L SSS + G ++
Sbjct: 593 LPPKGLAGPPAS--PGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQI 650
Query: 494 TSQV-DNLQKQPQEELQKESGPLQGKGK-PRAWARAWAAALENSSPKNLERSAGQS---- 547
+ + D P ++ P K + P A A AA P + ++ QS
Sbjct: 651 LTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTP 710
Query: 548 ----SPAKEGPL---DLYPKLADTIQTNPIPTHLSLVDSAQASPMPVDSVEA---DPTAV 597
+P +E P+ D P + +P P + +P ++ E DP
Sbjct: 711 QTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWP 770
Query: 598 GPVLAGPVPVDPGLVDLASTSS---ELVEPLPAEP-----VLINPVLADSAAVDPAVVPI 649
P P D + D + P PA P ++ +P + S+A + P
Sbjct: 771 PPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPP 830
Query: 650 SDNLPPVDAVPSGPAPVD--------LALVDPV--------PND------LTPVDPVLVK 687
PP P PAP L +PV P + +TP +V+
Sbjct: 831 GSPDPP--PAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVR 888
Query: 688 SRPTDPRRGAVSSALGGSAPQLLVE-------SESLDPPKTIIPEVKEVVDSLKIESGTS 740
R GA + ALG SAPQ + S P + V+ SL G S
Sbjct: 889 LRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLS 948
Query: 741 ATTH----EARPRP----LSLSEYRRRRQQRQAETEERSPQPPTGKWPSLPETPTGL--- 789
+ EA PRP S + + + R+ + E P PET L
Sbjct: 949 SAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLER----------PVSPETQADLQRN 998
Query: 790 --ADIPCLVIPPAPAKKTALQRSPETPLEICLVPVGPSPASPSPEPPVSKPVASSPTEQV 847
A++ + P A ++SP+ P + P P SP P ++P+ + PT +
Sbjct: 999 LVAELRSISEQRPPQ---APKKSPKAPPPVARKPSVGVPPPASPSYPRAEPLTAPPTNGL 1055
Query: 848 P 848
P
Sbjct: 1056 P 1056
Score = 37.7 bits (86), Expect = 0.094
Identities = 48/178 (26%), Positives = 70/178 (39%), Gaps = 9/178 (5%)
Query: 1338 GPAAPPPPCIAASREP--LDHRTSSEQADPSAPCLAPSSLLSPEASPCRNDMNTRTPPEP 1395
GPA P P ++ S + L P+ +A S C +++ +P
Sbjct: 333 GPAEPLSPAMSISPQATYLSKLIPHAVLPPTVDVVALGRCSLRTLSRC--SLHSASPASV 390
Query: 1396 SAKQRSMRCYRKACRSASPSSQGWQGRRGRNSRS-VSSGSNRTSEASSSSSSSSSSSRSR 1454
+ R RS PSS ++S + VS GS +S+ S SS++
Sbjct: 391 RSLGRFSSVSSPQPRSRHPSSSSDTWSHSQSSDTIVSDGSTLSSKGGSEGQPESSTA--- 447
Query: 1455 SRSLSPPHKRWRRSSCSSSGRSRRCSSSSSSSSSSSSSSSSSSSSRSRSRSPSPRRRS 1512
S S+ PP + S SG S +S + S SS S S S R R P P RR+
Sbjct: 448 SNSVVPPPQGGSGRG-SPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPPPPPRRT 504
Score = 36.2 bits (82), Expect = 0.27
Identities = 52/182 (28%), Positives = 76/182 (41%), Gaps = 18/182 (9%)
Query: 1363 ADPSAPCLAPSSLLSPEASPCRNDMNTRTPPEPSAKQRSMRCY-----RKACRSASPSSQ 1417
A P+ P L+P+ +SP+A+ + P RC R + SASP+S
Sbjct: 332 AGPAEP-LSPAMSISPQATYLSKLIPHAVLPPTVDVVALGRCSLRTLSRCSLHSASPASV 390
Query: 1418 GWQGRRGR------NSRSVSSGSNRTSEASSSSS--SSSSSSRSRSRSLSPPHKRWRRSS 1469
GR SR SS S+ S + SS + S S+ S+ S P +S
Sbjct: 391 RSLGRFSSVSSPQPRSRHPSSSSDTWSHSQSSDTIVSDGSTLSSKGGSEGQPESSTASNS 450
Query: 1470 C--SSSGRSRRCSSSSSSSSSSSSSSSSSSSSRSRSRSPSPRRRSDRRRRYSSYRSHDHY 1527
G S R S S S++ +S + S SS + RS S R+ +R R+H +
Sbjct: 451 VVPPPQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKL--KRPPPPPRRTHSLH 508
Query: 1528 QR 1529
QR
Sbjct: 509 QR 510
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 85.1 bits (209), Expect = 5e-16
Identities = 77/263 (29%), Positives = 102/263 (38%), Gaps = 41/263 (15%)
Query: 835 VSKPVASSPTEQVPSQEMPLLARPSPPVQSVSPAVPTPPSMSAAL--PFPAGGLGMPPSL 892
++K + + E + PS P ++ P P P S + P PA G P
Sbjct: 542 LTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPP 601
Query: 893 PPPPLQPPSLPLSMGPVLPDPFTHYAPLPSWPCYPHVSP----SGYPCLPPPPT------ 942
PPPP PP PL G + P PS P +SP SG +PPPP
Sbjct: 602 PPPPPPPPP-PLPGGVCISSP-------PSLPGGTAISPPPPLSGDATIPPPPPLPEGVG 653
Query: 943 VPLVSGTPGAYAVPPTCSVPWA---PPPAPVSPYSSTCTYGPLGWGPGPQHAPFWSTVPP 999
+P S PG A+PP +P + PPP P P G G P P P + +PP
Sbjct: 654 IPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLP-------GSAGIPPPPPPLPGEAGMPP 706
Query: 1000 PPLPPASIGRAVPQPKMESRGTPAGPPENVLPLSMAPPLSLGLPGHGAPQTEPTKVEVKP 1059
PP PP G +P P G PP + + PP G+P AP V P
Sbjct: 707 PP-PPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVP--AAP--------VLP 755
Query: 1060 VPASPHPKHKVSALVQSPQMKAL 1082
+P +K ++ P L
Sbjct: 756 FGLTPKKLYKPEVQLRRPNWSKL 778
Score = 84.0 bits (206), Expect = 1e-15
Identities = 93/339 (27%), Positives = 124/339 (36%), Gaps = 52/339 (15%)
Query: 714 ESLDPPKTIIPEVKEVVDSLKIESGTSATTHEARPRPLSL-SEYRRRRQQRQAETE---E 769
+ +D K E K K++S +A HE + + S++ ++ Q Q E +
Sbjct: 458 QMIDKTKVEKSEAKAAELEKKLDSELTAR-HELQVEMKKMESDFEQKLQDLQGEKDALHS 516
Query: 770 RSPQPPTGKWPSLPETPTGLADIPCLVIPPAPAKKTALQRSPETPLEICLVPVGPSPASP 829
Q T K E ++ L AKK L + V PS S
Sbjct: 517 EKQQIATEKQDLEAEVSQLTGEVAKLTKELEDAKKEMAS------LSAAAITVPPSVPSR 570
Query: 830 SPEPPVSKPVASSPTEQVPSQEMPLLARPSPPVQSVSPAVPTPPSMSAALPFPAG-GLGM 888
+P P P +P ++ P P S +P P PP P P G +
Sbjct: 571 APVP---------PAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPP-PLPGGVCISS 620
Query: 889 PPSLPPPPLQPPSLPLSMGPVLPDPFTHYAPLPSWPCYPHVSPSGYP---CLPPPPTVP- 944
PPSLP P PLS +P P PLP P SPS P +PPPP +P
Sbjct: 621 PPSLPGGTAISPPPPLSGDATIPPP----PPLPEGVGIP--SPSSLPGGTAIPPPPPLPG 674
Query: 945 LVSGTPGAYAVPPTCSVPWAPPPAPVSPYSSTCTYGPLGWGPGPQHAPFWSTVPPPP--- 1001
P +P + +P PPP P G G P P P +PPPP
Sbjct: 675 SARIPPPPPPLPGSAGIPPPPPPLP----------GEAGMPPPPPPLPGGPGIPPPPPFP 724
Query: 1002 ----LPPASIGRAVPQPKMESRGTPAGPPENVLPLSMAP 1036
+PP G +P P G PA P VLP + P
Sbjct: 725 GGPGIPPPPPGMGMPPPPPFGFGVPAAP---VLPFGLTP 760
Score = 43.9 bits (102), Expect = 0.001
Identities = 50/180 (27%), Positives = 61/180 (33%), Gaps = 38/180 (21%)
Query: 945 LVSGTPGAYAVPPTCSVPWAPPPAPVSPYSSTCTYGPLGWGPGPQHAPFWSTVPPPPLPP 1004
+ S + A VPP+ PPAP P S T P PG P PPPP PP
Sbjct: 553 MASLSAAAITVPPSVPSRAPVPPAPPLPGDSG-TIIPPPPAPGDSTTPPPPPPPPPPPPP 611
Query: 1005 ASIGRAVPQPKMESRGTPAGPPENVLPLSMAPPLSLGLPGHGAPQTEPTKVEVKPVPASP 1064
G + P GT PP PPLS G P E +P SP
Sbjct: 612 LPGGVCISSPPSLPGGTAISPP---------PPLS----GDATIPPPPPLPEGVGIP-SP 657
Query: 1065 HPKHKVSALVQSPQMKALACVSAEGVTVEEPASERLKPETQETRPREKPPLPATKAVPTP 1124
+A+ P + P S R+ P PPLP + +P P
Sbjct: 658 SSLPGGTAIPPPPPL---------------PGSARIPPPP--------PPLPGSAGIPPP 694
>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
Length = 1272
Score = 85.1 bits (209), Expect = 5e-16
Identities = 77/263 (29%), Positives = 102/263 (38%), Gaps = 41/263 (15%)
Query: 835 VSKPVASSPTEQVPSQEMPLLARPSPPVQSVSPAVPTPPSMSAAL--PFPAGGLGMPPSL 892
++K + + E + PS P ++ P P P S + P PA G P
Sbjct: 551 LTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPP 610
Query: 893 PPPPLQPPSLPLSMGPVLPDPFTHYAPLPSWPCYPHVSP----SGYPCLPPPPT------ 942
PPPP PP PL G + P PS P +SP SG +PPPP
Sbjct: 611 PPPPPPPPP-PLPGGVCISSP-------PSLPGGTAISPPPPLSGDATIPPPPPLPEGVG 662
Query: 943 VPLVSGTPGAYAVPPTCSVPWA---PPPAPVSPYSSTCTYGPLGWGPGPQHAPFWSTVPP 999
+P S PG A+PP +P + PPP P P G G P P P + +PP
Sbjct: 663 IPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLP-------GSAGIPPPPPPLPGEAGMPP 715
Query: 1000 PPLPPASIGRAVPQPKMESRGTPAGPPENVLPLSMAPPLSLGLPGHGAPQTEPTKVEVKP 1059
PP PP G +P P G PP + + PP G+P AP V P
Sbjct: 716 PP-PPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVP--AAP--------VLP 764
Query: 1060 VPASPHPKHKVSALVQSPQMKAL 1082
+P +K ++ P L
Sbjct: 765 FGLTPKKLYKPEVQLRRPNWSKL 787
Score = 84.0 bits (206), Expect = 1e-15
Identities = 93/339 (27%), Positives = 124/339 (36%), Gaps = 52/339 (15%)
Query: 714 ESLDPPKTIIPEVKEVVDSLKIESGTSATTHEARPRPLSL-SEYRRRRQQRQAETE---E 769
+ +D K E K K++S +A HE + + S++ ++ Q Q E +
Sbjct: 467 QMIDKTKVEKSEAKAAELEKKLDSELTAR-HELQVEMKKMESDFEQKLQDLQGEKDALHS 525
Query: 770 RSPQPPTGKWPSLPETPTGLADIPCLVIPPAPAKKTALQRSPETPLEICLVPVGPSPASP 829
Q T K E ++ L AKK L + V PS S
Sbjct: 526 EKQQIATEKQDLEAEVSQLTGEVAKLTKELEDAKKEMAS------LSAAAITVPPSVPSR 579
Query: 830 SPEPPVSKPVASSPTEQVPSQEMPLLARPSPPVQSVSPAVPTPPSMSAALPFPAG-GLGM 888
+P P P +P ++ P P S +P P PP P P G +
Sbjct: 580 APVP---------PAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPP-PLPGGVCISS 629
Query: 889 PPSLPPPPLQPPSLPLSMGPVLPDPFTHYAPLPSWPCYPHVSPSGYP---CLPPPPTVP- 944
PPSLP P PLS +P P PLP P SPS P +PPPP +P
Sbjct: 630 PPSLPGGTAISPPPPLSGDATIPPP----PPLPEGVGIP--SPSSLPGGTAIPPPPPLPG 683
Query: 945 LVSGTPGAYAVPPTCSVPWAPPPAPVSPYSSTCTYGPLGWGPGPQHAPFWSTVPPPP--- 1001
P +P + +P PPP P G G P P P +PPPP
Sbjct: 684 SARIPPPPPPLPGSAGIPPPPPPLP----------GEAGMPPPPPPLPGGPGIPPPPPFP 733
Query: 1002 ----LPPASIGRAVPQPKMESRGTPAGPPENVLPLSMAP 1036
+PP G +P P G PA P VLP + P
Sbjct: 734 GGPGIPPPPPGMGMPPPPPFGFGVPAAP---VLPFGLTP 769
Score = 43.9 bits (102), Expect = 0.001
Identities = 50/180 (27%), Positives = 61/180 (33%), Gaps = 38/180 (21%)
Query: 945 LVSGTPGAYAVPPTCSVPWAPPPAPVSPYSSTCTYGPLGWGPGPQHAPFWSTVPPPPLPP 1004
+ S + A VPP+ PPAP P S T P PG P PPPP PP
Sbjct: 562 MASLSAAAITVPPSVPSRAPVPPAPPLPGDSG-TIIPPPPAPGDSTTPPPPPPPPPPPPP 620
Query: 1005 ASIGRAVPQPKMESRGTPAGPPENVLPLSMAPPLSLGLPGHGAPQTEPTKVEVKPVPASP 1064
G + P GT PP PPLS G P E +P SP
Sbjct: 621 LPGGVCISSPPSLPGGTAISPP---------PPLS----GDATIPPPPPLPEGVGIP-SP 666
Query: 1065 HPKHKVSALVQSPQMKALACVSAEGVTVEEPASERLKPETQETRPREKPPLPATKAVPTP 1124
+A+ P + P S R+ P PPLP + +P P
Sbjct: 667 SSLPGGTAIPPPPPL---------------PGSARIPPPP--------PPLPGSAGIPPP 703
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 84.7 bits (208), Expect = 7e-16
Identities = 105/413 (25%), Positives = 138/413 (33%), Gaps = 96/413 (23%)
Query: 772 PQPPTGKWPSLPETPTGLA-----DIPCLVIPPAPAKKTALQRSPETPLEIC------LV 820
P PP P LP P A + P V+P ++K R P TP +
Sbjct: 431 PPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRG--RPPLTPSQRAEREAARAG 488
Query: 821 PVGPSPASPSPEPPVSKPVASSPTEQVPSQE---------MPLLAR-------------- 857
P G SP +P+P P SPT S MP+++
Sbjct: 489 PEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMD 548
Query: 858 ---PSPPVQSVSPAVPTPPSMSAALPFPAGGLGMPPSLPPPPLQPPSLPLSMGPVLPDPF 914
P PP VSP + P + S +P + PP P PP P LP +L +P
Sbjct: 549 EDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPT 608
Query: 915 THYAPLPSWPCYPHVSPSGYPCLPPPPTVPLVSGTPGAYAVPPTCSVPWAPPPAPVSPYS 974
+ L P +P P PPP S P P + P A + Y
Sbjct: 609 FRWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAP-----QFTPSEAHLKIYE 663
Query: 975 STCTYGPLGWGPGPQHAPFWSTVPPPPLPPASIGRAVPQPKMESRGTPAGPPENVLPLSM 1034
S T PLG AP P P PPA A P+P+ R
Sbjct: 664 SVLTPPPLG-------AP---EAPEPEPPPADDSPAEPEPRAVGRTN------------- 700
Query: 1035 APPLSLGLPGHGAPQTEPTKVEVKPVPASPHPKHKVSALVQSPQMKALACVSAEGVTVEE 1094
L LP T P K EV P H AL PQ +A + +
Sbjct: 701 ----HLSLPRFAPVVTTPVKAEVSP--------HGAPALSNGPQTQAQLLQPLQAL---- 744
Query: 1095 PASERLKPETQETRPREKPPLPATKAVPTPRQSTVPKLPAVHPARLRKLSFLP 1147
+TQ PP P + P+P+Q +P + AR+ + LP
Sbjct: 745 --------QTQLLPQALPPPQPQLQPPPSPQQ-----MPPLEKARIAGVGSLP 784
Score = 66.6 bits (161), Expect = 2e-10
Identities = 112/448 (25%), Positives = 152/448 (33%), Gaps = 119/448 (26%)
Query: 845 EQVPSQEMPLLARPSPPVQSVSPAVPTPPSMSAALPFPAGGLGMPPSLPPPPLQPPSLPL 904
E +P+ E P PP+ TPP+ S P P P + PPPPL PP P
Sbjct: 389 EMMPAAEKEEAKLPPPPL--------TPPAPSPPPPLPP-----PSTSPPPPLCPPPPPP 435
Query: 905 SMGPVLPDPFTHYAPLPSWPCYPHVSPSGYPCLPPPPTVPLVSGTPGAYAVPPTCSVPWA 964
P LP P PPPP +P VP TCS
Sbjct: 436 VSPPPLPSP------------------------PPPPAQEEQEESPPP-VVPATCSRKRG 470
Query: 965 PPP-------------------APVSPYSSTCTYGPLGWGP--GPQHAPFWSTVPP--PP 1001
PP +P +P ST T GP P P+ F + P
Sbjct: 471 RPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMP 530
Query: 1002 LPPASIGRAVPQPKMESRGTPAGPPENVLPLSMAPPLSLGLPGHGAPQTEPTKVEVKPVP 1061
+ A R + P+ P PP+ + + PP++ P PQ E PVP
Sbjct: 531 VVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPP---VPQ------EPAPVP 581
Query: 1062 ASPHPKHKVSALVQSPQMKALACVSAEGVTVEEPASERLKPETQETRPREKPPLPATKAV 1121
+ P S V P+ + ++ + R T+E PP PA
Sbjct: 582 SPPRAPTPPSTPVPLPEKRR---------SILREPTFRWTSLTREL----PPPPPAPPPP 628
Query: 1122 PTPRQSTVPKLPAVHPARLRKLSFLPTPRTQGSEDVVQAFISEIGIEASDLSSLLEQFEK 1181
P P P + P LR F P SE ++ +
Sbjct: 629 PAPSPPPAPATSSRRPLLLRAPQFTP---------------SEAHLKIYESVLTPPPLGA 673
Query: 1182 SEAKKECPPPA---PA--DSLAVGNSGGVDIPQ--------EKRPLDRLQAPELANVAGL 1228
EA + PPPA PA + AVG + + +P+ K + AP L+N
Sbjct: 674 PEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSN---- 729
Query: 1229 TPPATPPHQLWKPLAAV--SLLAKAKSP 1254
P T QL +PL A+ LL +A P
Sbjct: 730 -GPQTQA-QLLQPLQALQTQLLPQALPP 755
Score = 53.1 bits (126), Expect = 2e-06
Identities = 111/497 (22%), Positives = 158/497 (31%), Gaps = 132/497 (26%)
Query: 762 QRQAETEERSPQPPTGKWPSLPETPTGLADIPCLVIPPAPAKKTALQRSPETPLEICLVP 821
+R +P+PP +W S P L P L +PP + TAL TP L P
Sbjct: 1911 RRSRRPSPLAPRPPPSRWASPP-----LKTSPQLRVPPPTSVVTAL-----TPTSGELAP 1960
Query: 822 VGPSPASPSPE---------------PPVSKPVASSPTEQVPSQEMPLLA------RPSP 860
GP+P+ P PE A+S P QE + A P
Sbjct: 1961 PGPAPSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGP 2020
Query: 861 PVQSVSPAVPTPPSMSAALPFPAGGLGMPPSLPPPPLQPPSLPLSMGPVLPDPFTHYAPL 920
S + PT S + FP + P P P + G + D A
Sbjct: 2021 GDSSEEESSPT----SRYIHFPVTVVSAPGLAPSATPGAPRIEQLDG--VDDGTDSEAEA 2074
Query: 921 PSWPCYPHVSPSGYPCLPPPPTVPLVSGTPGAYAVPPTCSVPWAPPPAPVSPYSSTCTYG 980
P PSG P V G G A PP P+ + + G
Sbjct: 2075 VQQPRGQGTPPSG-----PGVVRAGVLGAAGDRARPP------EDLPSEIVDFVLKNLGG 2123
Query: 981 PLGWGPGPQHAPFWSTVPPPPLPPASIGRAVPQPKMESRGTPAGPPENVLPLSMAPPLSL 1040
P G GP+ PP PP + G QP +PA P L AP + +
Sbjct: 2124 PGDGGAGPREESL------PPAPPLANG---SQPSQGLTASPADPTRTFAWLPGAPGVRV 2174
Query: 1041 GLPGHGAPQTEPTKVEVKPVPASPHPKHKVSALVQSPQMKALACVSAEGVTVEEPASERL 1100
+ + P P P P LV + + ++ EG V P
Sbjct: 2175 --------------LSLGPAPEPPKPATSKIILV-NKLGQVFVKMAGEGEPVPPPV---- 2215
Query: 1101 KPETQETRPREKPPLPATKAVPTPRQSTVPKLPAVHPARLRKLSFLPTPRTQGSEDVVQA 1160
++PPLP T + P T+P P L LP
Sbjct: 2216 ----------KQPPLPPTISPTAPTSWTLPPGPL--------LGVLPV------------ 2245
Query: 1161 FISEIGIEASDLSSLLEQFEKSEAKKECPPPAPADSLAVGNSGGVDIPQEKRPLDRLQAP 1220
+G+ + PPP P V +SG P++ ++
Sbjct: 2246 ----VGV-----------------VRPAPPPPPPPLTLVLSSGPASPPRQ-----AIRVK 2279
Query: 1221 ELANVAGLTPPATPPHQ 1237
++ +G +PPA PP++
Sbjct: 2280 RVSTFSGRSPPAPPPYK 2296
Score = 47.0 bits (110), Expect = 2e-04
Identities = 147/688 (21%), Positives = 213/688 (30%), Gaps = 158/688 (22%)
Query: 624 PLPAEPVLINPVLADSAAVDPAVVPISDNLPPVDAVPSGPAPVDLALVDPVPNDLTPVDP 683
PL P L P +V A+ P S L P PS P P DL P D+ V
Sbjct: 1932 PLKTSPQLRVP---PPTSVVTALTPTSGELAPPGPAPSPPPPEDLG---PDFEDMEVVSG 1985
Query: 684 V----------LVKSRPTDPR---RGAVSSALGGSAPQLLVESESLDPPKTIIPEVKEVV 730
+ L+ + P GA+ S+ GG E P I VV
Sbjct: 1986 LSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDS---SEEESSPTSRYIHFPVTVV 2042
Query: 731 DSLKIESGTSATTHEARPRPLSLSEYRRRRQQRQAETEERSPQPPTGKWPSLPETPTGLA 790
+ G + + PR L ++E + Q P G+ P+G
Sbjct: 2043 SA----PGLAPSATPGAPRIEQLDGV-----DDGTDSEAEAVQQPRGQGTP----PSGPG 2089
Query: 791 DIPCLVIPPAPAKKTALQRSPETPLEICLVPVG-PSPASPSPEPPVSKPVASSPTEQVPS 849
+ V+ A + + P ++ L +G P P P
Sbjct: 2090 VVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESLPPA---------- 2139
Query: 850 QEMPLLARPSPPVQSVSPAVPTPPSMSAALPFPAG----GLGMPPSLPPPPLQPPSLPLS 905
P LA S P Q ++ + P A LP G LG P P P L
Sbjct: 2140 ---PPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNK 2196
Query: 906 MGPVLPDPFTHYAPLPSWPCYPHVSPSGYPCLPPPPTVPLVSGTPGAYAVPPTCSVPWAP 965
+G V P+P P + PP P +S PT W
Sbjct: 2197 LGQVFVKMAGEGEPVP-------------PPVKQPPLPPTIS---------PTAPTSWTL 2234
Query: 966 PPAPVSPYSSTCTYGPLGWGPGPQHAPFWSTVPPPPLPPASIGRAVPQPKMESRGTPAGP 1025
PP P+ LG P PPPP PP ++ + S G PA P
Sbjct: 2235 PPGPL-----------LGVLP---VVGVVRPAPPPPPPPLTL--------VLSSG-PASP 2271
Query: 1026 PENVLPLSMAPPLSLGLPGHGAPQTEPTKVEVKPVPASPHPKHKVSALVQSPQMKALACV 1085
P + + S G P P K +P A +PQ+ L
Sbjct: 2272 PRQAIRVKRVSTFS----GRSPPAPPPYK--------APRLDEDGEASEDTPQVPGLGSG 2319
Query: 1086 SAEGVTVEEPASERLKPETQETRPREKPPLPATKAVPTPRQSTVPKLPAVHPARLRKLSF 1145
V ++ P + ++P PA + P P Q P LP
Sbjct: 2320 GFSRVRMKTPT-------VRGVLDLDRPGEPAGEESPGPLQERSPLLPLPEDG------- 2365
Query: 1146 LPTPRTQGSEDVVQAFISEIGIEASDLSSLLEQFEKSEAKKECPPPAPADSLAVGNSGGV 1205
P G D++ L S + + E PP+P D
Sbjct: 2366 -PPQVPDGPPDLL-------------LESQWHHYSGEASSSEEEPPSPDDK-------EN 2404
Query: 1206 DIPQEKRPLDRLQAPELANVAGLTPPATPPHQLWKPLAAVSLLAKAKSPKSTAQEGTLKP 1265
P+ P R E+++ G + A W+ +L+ K + + A+ L
Sbjct: 2405 QAPKRTGPHLRF---EISSEDGFSVEAESLEGAWR-----TLIEKVQEARGHARLRHLSF 2456
Query: 1266 EGVTEAK-----HPAAVRLQEGVHGPSR 1288
G++ A+ H A + L E + G R
Sbjct: 2457 SGMSGARLLGIHHDAVIFLAEQLPGAQR 2484
Score = 38.5 bits (88), Expect = 0.055
Identities = 126/558 (22%), Positives = 176/558 (31%), Gaps = 127/558 (22%)
Query: 890 PSLPPPPLQPPSLPLSMGPVLPDPFTHYAPLPSWPCYPHVSPSGYPCLPPPPTVPLVSGT 949
PS PP + P PL ++P ++P+ + P + P PP P S +
Sbjct: 1810 PSSEPPGGEDP--PLDTDVLVPGAPERHSPIQNLD--PPLRPDSGSAPPPAPR----SFS 1861
Query: 950 PGAYAVP-------PTCSVPWAPPPAPVSPYSSTCTYGPLGWGPGPQHAPFWSTVPPP-- 1000
VP P V + P P+P SP S T H P TV P
Sbjct: 1862 GARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLT------------HHIP---TVGDPDF 1906
Query: 1001 PLPPASIGRAVPQPKMESRGTPAGPPENVLPLSMAPPLSLGLPGHGAPQTEPTKVEVKPV 1060
P PP R P A PP P PP P PT E+ P
Sbjct: 1907 PAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPP-----PTSVVTALTPTSGELAPP 1961
Query: 1061 PASPHP------------------------KHKVSALVQSPQMKALACVSAEGVTVEEPA 1096
+P P S L P + + A G + P
Sbjct: 1962 GPAPSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPG 2021
Query: 1097 SERLKPETQETR----PREKPPLPATKAVPTPRQSTVPKLPAVHPARLRKLSFLPTPRTQ 1152
+ + +R P P TP + +L V + + PR Q
Sbjct: 2022 DSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQ 2081
Query: 1153 GS----EDVVQA-FISEIGIEA---SDLSSLLEQFEKSEAKKECPPPAPADSLAVGNSGG 1204
G+ VV+A + G A DL S + F +L GG
Sbjct: 2082 GTPPSGPGVVRAGVLGAAGDRARPPEDLPSEIVDF-------------VLKNLGGPGDGG 2128
Query: 1205 VDIPQEKRPLDRLQAPELANVA----GLT-PPATPPHQL-WKPLA-AVSLLAKAKSPKST 1257
+E P AP LAN + GLT PA P W P A V +L+ +P+
Sbjct: 2129 AGPREESLP----PAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPE-P 2183
Query: 1258 AQEGTLKPEGVTEAKHPAAVRLQEGVHGPSRVHVGSGDHDYCVRSRTPPKKMPALVIPEV 1317
+ T K V + EG P V + PP +P + P
Sbjct: 2184 PKPATSKIILVNKLGQVFVKMAGEGEPVPPPV-------------KQPP--LPPTISPTA 2228
Query: 1318 GSRWNVKRHQDITIKPVLSLGPAAPPPPCIAASREPLDHRTSSEQADPSAPCLAPSSLLS 1377
+ W + + + PV+ + APPPP PL SS A P + +
Sbjct: 2229 PTSWTLPPGPLLGVLPVVGVVRPAPPPP-----PPPLTLVLSSGPASPPRQAIRVKRV-- 2281
Query: 1378 PEASPCRNDMNTRTPPEP 1395
+ + R+PP P
Sbjct: 2282 -------STFSGRSPPAP 2292
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.129 0.382
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 86,241,393
Number of Sequences: 37866
Number of extensions: 5783359
Number of successful extensions: 82959
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 710
Number of HSP's successfully gapped in prelim test: 2301
Number of HSP's that attempted gapping in prelim test: 32957
Number of HSP's gapped (non-prelim): 26623
length of query: 1664
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1548
effective length of database: 13,855,062
effective search space: 21447635976
effective search space used: 21447635976
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.