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Search of human proteins with 40807351
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40807351 solute carrier family 36 (proton/amino acid
symporter), member 4 [Homo sapiens]
(504 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40807351 solute carrier family 36 (proton/amino acid symporte... 1003 0.0
gi|41352721 solute carrier family 36 member 1 [Homo sapiens] 481 e-136
gi|222418631 solute carrier family 36, member 2 [Homo sapiens] 465 e-131
gi|222446640 solute carrier family 36, member 3 isoform 2 [Homo ... 425 e-119
gi|222446642 solute carrier family 36, member 3 isoform 1 [Homo ... 405 e-113
gi|24429574 solute carrier family 38, member 6 [Homo sapiens] 80 6e-15
gi|17999520 solute carrier family 32, member 1 [Homo sapiens] 64 2e-10
gi|193788624 solute carrier family 38, member 5 [Homo sapiens] 60 4e-09
gi|117168277 amino acid transporter system A1 [Homo sapiens] 58 2e-08
gi|117168275 amino acid transporter system A1 [Homo sapiens] 58 2e-08
gi|5870893 solute carrier family 38, member 3 [Homo sapiens] 57 4e-08
gi|219689132 solute carrier family 38, member 4 [Homo sapiens] 54 3e-07
gi|18482385 solute carrier family 38, member 4 [Homo sapiens] 54 3e-07
gi|83921602 solute carrier family 38, member 10 isoform a [Homo ... 52 2e-06
gi|20070376 solute carrier family 38, member 10 isoform b [Homo ... 52 2e-06
gi|222418629 solute carrier family 38, member 9 [Homo sapiens] 47 4e-05
gi|21361602 solute carrier family 38, member 2 [Homo sapiens] 45 1e-04
gi|27735137 solute carrier family 38, member 11 [Homo sapiens] 39 0.014
gi|198041678 solute carrier family 12 (potassium-chloride transp... 34 0.36
gi|11968148 solute carrier family 12 (potassium-chloride transpo... 34 0.36
gi|123701900 solute carrier family 12 (potassium/chloride transp... 34 0.36
gi|157388943 transmembrane protein 104 [Homo sapiens] 32 1.0
gi|5729798 cysteinyl leukotriene receptor 1 [Homo sapiens] 32 1.4
gi|110224458 solute carrier family 12, member 6 isoform e [Homo ... 32 1.4
gi|110224456 solute carrier family 12, member 6 isoform d [Homo ... 32 1.4
gi|110224454 solute carrier family 12, member 6 isoform c [Homo ... 32 1.4
gi|110224452 solute carrier family 12, member 6 isoform c [Homo ... 32 1.4
gi|4826780 solute carrier family 12, member 6 isoform b [Homo sa... 32 1.4
gi|110224449 solute carrier family 12, member 6 isoform a [Homo ... 32 1.4
gi|225579067 solute carrier family 12, member 4 isoform e [Homo ... 32 1.8
>gi|40807351 solute carrier family 36 (proton/amino acid symporter),
member 4 [Homo sapiens]
Length = 504
Score = 1003 bits (2592), Expect = 0.0
Identities = 504/504 (100%), Positives = 504/504 (100%)
Query: 1 MEAAATPAAAGAARREELDMDVMRPLINEQNFDGTSDEEHEQELLPVQKHYQLDDQEGIS 60
MEAAATPAAAGAARREELDMDVMRPLINEQNFDGTSDEEHEQELLPVQKHYQLDDQEGIS
Sbjct: 1 MEAAATPAAAGAARREELDMDVMRPLINEQNFDGTSDEEHEQELLPVQKHYQLDDQEGIS 60
Query: 61 FVQTLMHLLKGNIGTGLLGLPLAIKNAGIVLGPISLVFIGIISVHCMHILVRCSHFLCLR 120
FVQTLMHLLKGNIGTGLLGLPLAIKNAGIVLGPISLVFIGIISVHCMHILVRCSHFLCLR
Sbjct: 61 FVQTLMHLLKGNIGTGLLGLPLAIKNAGIVLGPISLVFIGIISVHCMHILVRCSHFLCLR 120
Query: 121 FKKSTLGYSDTVSFAMEVSPWSCLQKQAAWGRSVVDFFLVITQLGFCSVYIVFLAENVKQ 180
FKKSTLGYSDTVSFAMEVSPWSCLQKQAAWGRSVVDFFLVITQLGFCSVYIVFLAENVKQ
Sbjct: 121 FKKSTLGYSDTVSFAMEVSPWSCLQKQAAWGRSVVDFFLVITQLGFCSVYIVFLAENVKQ 180
Query: 181 VHEGFLESKVFISNSTNSSNPCERRSVDLRIYMLCFLPFIILLVFIRELKNLFVLSFLAN 240
VHEGFLESKVFISNSTNSSNPCERRSVDLRIYMLCFLPFIILLVFIRELKNLFVLSFLAN
Sbjct: 181 VHEGFLESKVFISNSTNSSNPCERRSVDLRIYMLCFLPFIILLVFIRELKNLFVLSFLAN 240
Query: 241 VSMAVSLVIIYQYVVRNMPDPHNLPIVAGWKKYPLFFGTAVFAFEGIGVVLPLENQMKES 300
VSMAVSLVIIYQYVVRNMPDPHNLPIVAGWKKYPLFFGTAVFAFEGIGVVLPLENQMKES
Sbjct: 241 VSMAVSLVIIYQYVVRNMPDPHNLPIVAGWKKYPLFFGTAVFAFEGIGVVLPLENQMKES 300
Query: 301 KRFPQALNIGMGIVTTLYVTLATLGYMCFHDEIKGSITLNLPQDVWLYQSVKILYSFGIF 360
KRFPQALNIGMGIVTTLYVTLATLGYMCFHDEIKGSITLNLPQDVWLYQSVKILYSFGIF
Sbjct: 301 KRFPQALNIGMGIVTTLYVTLATLGYMCFHDEIKGSITLNLPQDVWLYQSVKILYSFGIF 360
Query: 361 VTYSIQFYVPAEIIIPGITSKFHTKWKQICEFGIRSFLVSITCAGAILIPRLDIVISFVG 420
VTYSIQFYVPAEIIIPGITSKFHTKWKQICEFGIRSFLVSITCAGAILIPRLDIVISFVG
Sbjct: 361 VTYSIQFYVPAEIIIPGITSKFHTKWKQICEFGIRSFLVSITCAGAILIPRLDIVISFVG 420
Query: 421 AVSSSTLALILPPLVEILTFSKEHYNIWMVLKNISIAFTGVVGFLLGTYITVEEIIYPTP 480
AVSSSTLALILPPLVEILTFSKEHYNIWMVLKNISIAFTGVVGFLLGTYITVEEIIYPTP
Sbjct: 421 AVSSSTLALILPPLVEILTFSKEHYNIWMVLKNISIAFTGVVGFLLGTYITVEEIIYPTP 480
Query: 481 KVVAGTPQSPFLNLNSTCLTSGLK 504
KVVAGTPQSPFLNLNSTCLTSGLK
Sbjct: 481 KVVAGTPQSPFLNLNSTCLTSGLK 504
>gi|41352721 solute carrier family 36 member 1 [Homo sapiens]
Length = 476
Score = 481 bits (1239), Expect = e-136
Identities = 247/439 (56%), Positives = 322/439 (73%), Gaps = 13/439 (2%)
Query: 60 SFVQTLMHLLKGNIGTGLLGLPLAIKNAGIVLGPISLVFIGIISVHCMHILVRCSHFLCL 119
++ QTL+HLLKGNIGTGLLGLPLA+KNAGIV+GPISL+ IGI++VHCM ILV+C+H C
Sbjct: 48 TWFQTLIHLLKGNIGTGLLGLPLAVKNAGIVMGPISLLIIGIVAVHCMGILVKCAHHFCR 107
Query: 120 RFKKSTLGYSDTVSFAMEVSPWSCLQKQAAWGRSVVDFFLVITQLGFCSVYIVFLAENVK 179
R KS + Y DTV + +E SP S L+ A WGR VVDFFL++TQLGFC VY VFLA+N K
Sbjct: 108 RLNKSFVDYGDTVMYGLESSPCSWLRNHAHWGRRVVDFFLIVTQLGFCCVYFVFLADNFK 167
Query: 180 QVHEGFLESKVFISNSTNSSNPCERRSVDLRIYMLCFLPFIILLVFIRELKNLFVLSFLA 239
QV E + +N N+ ++D R+YML FLPF++LLVFIR L+ L + S LA
Sbjct: 168 QVIEA---ANGTTNNCHNNETVILTPTMDSRLYMLSFLPFLVLLVFIRNLRALSIFSLLA 224
Query: 240 NVSMAVSLVIIYQYVVRNMPDPHNLPIVAGWKKYPLFFGTAVFAFEGIGVVLPLENQMKE 299
N++M VSLV+IYQ++V+ +PDP +LP+VA WK YPLFFGTA+F+FEGIG+VLPLEN+MK+
Sbjct: 225 NITMLVSLVMIYQFIVQRIPDPSHLPLVAPWKTYPLFFGTAIFSFEGIGMVLPLENKMKD 284
Query: 300 SKRFPQALNIGMGIVTTLYVTLATLGYMCFHDEIKGSITLNLPQDVWLYQSVKILYSFGI 359
++FP L +GM IVT LY++L LGY+ F I+GSITLNLP + WLYQSVK+LYS GI
Sbjct: 285 PRKFPLILYLGMVIVTILYISLGCLGYLQFGANIQGSITLNLP-NCWLYQSVKLLYSIGI 343
Query: 360 FVTYSIQFYVPAEIIIPGITSKFHTKWKQICEFGIRSFLVSITCAGAILIPRLDIVISFV 419
F TY++QFYVPAEIIIP S+ + + + +R+ LV +TC AILIPRLD+VIS V
Sbjct: 344 FFTYALQFYVPAEIIIPFFVSRAPEHCELVVDLFVRTVLVCLTCILAILIPRLDLVISLV 403
Query: 420 GAVSSSTLALILPPLVEILTFSKEHYNIWMVLKNISIAFTGVVGFLLGTYITVEEIIYPT 479
G+VSSS LALI+PPL+E+ TF E + + K+ I+ G VGF++GTY + E+I P+
Sbjct: 404 GSVSSSALALIIPPLLEVTTFYSEGMSPLTIFKDALISILGFVGFVVGTYEALYELIQPS 463
Query: 480 PKVVAGTPQSPFLNLNSTC 498
+P +NSTC
Sbjct: 464 --------NAPIF-INSTC 473
>gi|222418631 solute carrier family 36, member 2 [Homo sapiens]
Length = 483
Score = 465 bits (1197), Expect = e-131
Identities = 242/480 (50%), Positives = 330/480 (68%), Gaps = 21/480 (4%)
Query: 4 AATPAAAGAARREELDMDVMRPLINE---QNFDGTSDEEHEQELLPVQKHYQLDDQEGIS 60
+ T + G + +D+M P + +N D T +E E ++K +GI+
Sbjct: 2 SVTKSTEGPQGAVAIKLDLMSPPESAKKLENKDSTFLDESPSESAGLKK------TKGIT 55
Query: 61 FVQTLMHLLKGNIGTGLLGLPLAIKNAGIVLGPISLVFIGIISVHCMHILVRCSHFLCLR 120
Q L+HL+KGN+GTG+LGLPLA+KNAGI++GP+SL+ +G I+ HCMHILV+C+ C R
Sbjct: 56 VFQALIHLVKGNMGTGILGLPLAVKNAGILMGPLSLLVMGFIACHCMHILVKCAQRFCKR 115
Query: 121 FKKSTLGYSDTVSFAMEVSPWSCLQKQAAWGRSVVDFFLVITQLGFCSVYIVFLAENVKQ 180
K + Y DTV +E +P + LQ A WGR +V FFL+ITQLGFC VYIVFLA+N+KQ
Sbjct: 116 LNKPFMDYGDTVMHGLEANPNAWLQNHAHWGRHIVSFFLIITQLGFCCVYIVFLADNLKQ 175
Query: 181 VHEGFLESKVFISNSTNSSNPCER----RSVDLRIYMLCFLPFIILLVFIRELKNLFVLS 236
V E ++++TN+ E ++D R+YML FLPF++LLV IR L+ L + S
Sbjct: 176 VVEA-------VNSTTNNCYSNETVILTPTMDSRLYMLSFLPFLVLLVLIRNLRILTIFS 228
Query: 237 FLANVSMAVSLVIIYQYVVRNMPDPHNLPIVAGWKKYPLFFGTAVFAFEGIGVVLPLENQ 296
LAN+SM VSLVII QY+ + +PDP LP+VA WK YPLFFGTA+F+FE IGVVLPLEN+
Sbjct: 229 MLANISMLVSLVIIIQYITQEIPDPSRLPLVASWKTYPLFFGTAIFSFESIGVVLPLENK 288
Query: 297 MKESKRFPQALNIGMGIVTTLYVTLATLGYMCFHDEIKGSITLNLPQDVWLYQSVKILYS 356
MK ++ FP L++GM IVT+LY+ +A LGY+ F D+IK SI+LNLP + WLYQSVK+LY
Sbjct: 289 MKNARHFPAILSLGMSIVTSLYIGMAALGYLRFGDDIKASISLNLP-NCWLYQSVKLLYI 347
Query: 357 FGIFVTYSIQFYVPAEIIIPGITSKFHTKWKQICEFGIRSFLVSITCAGAILIPRLDIVI 416
GI TY++QFYVPAEIIIP S+ T+W + IR +V +TC AILIPRLD+VI
Sbjct: 348 AGILCTYALQFYVPAEIIIPFAISRVSTRWALPLDLSIRLVMVCLTCLLAILIPRLDLVI 407
Query: 417 SFVGAVSSSTLALILPPLVEILTFSKEHYNIWMVLKNISIAFTGVVGFLLGTYITVEEII 476
S VG+VS + LALI+PPL+E+ TF E + + K+ I+ G VGF++GTY ++E++
Sbjct: 408 SLVGSVSGTALALIIPPLLEVTTFYSEGMSPLTIFKDALISILGFVGFVVGTYQALDELL 467
>gi|222446640 solute carrier family 36, member 3 isoform 2 [Homo
sapiens]
Length = 470
Score = 425 bits (1092), Expect = e-119
Identities = 216/438 (49%), Positives = 300/438 (68%), Gaps = 18/438 (4%)
Query: 56 QEGISFVQTLMHLLKGNIGTGLLGLPLAIKNAGIVLGPISLVFIGIISVHCMHILVRCSH 115
+ G+S +QTL+HLLK NIGTGLLGLPLAIKNAG+++GP+SL+ IG+++VHCM IL+ C+
Sbjct: 39 EAGLSMMQTLIHLLKCNIGTGLLGLPLAIKNAGLLVGPVSLLAIGVLTVHCMVILLNCAQ 98
Query: 116 FLCLRFKKSTLGYSDTVSFAMEVSPWSCLQKQAAWGRSVVDFFLVITQLGFCSVYIVFLA 175
L R +K+ + Y + + +E P + L+ A WGR V F LVITQLGFCSVY +F+A
Sbjct: 99 HLSQRLQKTFVNYGEATMYGLETCPNTWLRAHAVWGRYTVSFLLVITQLGFCSVYFMFMA 158
Query: 176 ENVKQVHEGFLESKVFISNSTNSSNPCERRSV-------DLRIYMLCFLPFIILLVFIRE 228
+N++Q+ + + +SN C+ R + D+R YML LPF+ILLVFI+
Sbjct: 159 DNLQQM----------VEKAHVTSNICQPREILTLTPILDIRFYMLIILPFLILLVFIQN 208
Query: 229 LKNLFVLSFLANVSMAVSLVIIYQYVVRNMPDPHNLPIVAGWKKYPLFFGTAVFAFEGIG 288
LK L V S LAN++ S+ +I++Y++ +P P NLP++A WK + LFFGTA+F FEG+G
Sbjct: 209 LKVLSVFSTLANITTLGSMALIFEYIMEGIPYPSNLPLMANWKTFLLFFGTAIFTFEGVG 268
Query: 289 VVLPLENQMKESKRFPQALNIGMGIVTTLYVTLATLGYMCFHDEIKGSITLNLPQDVWLY 348
+VLPL+NQMK ++F L +GM IV LY+ L TLGYM F + + SITLNLP + WLY
Sbjct: 269 MVLPLKNQMKHPQQFSFVLYLGMSIVIILYILLGTLGYMKFGSDTQASITLNLP-NCWLY 327
Query: 349 QSVKILYSFGIFVTYSIQFYVPAEIIIPGITSKFHTKWKQICEFGIRSFLVSITCAGAIL 408
QSVK++YS GIF TY++QF+VPAEIIIP S+ W + +RS LV +TC AIL
Sbjct: 328 QSVKLMYSIGIFFTYALQFHVPAEIIIPFAISQVSESWALFVDLSVRSALVCLTCVSAIL 387
Query: 409 IPRLDIVISFVGAVSSSTLALILPPLVEILTFSKEHYNIWMVLKNISIAFTGVVGFLLGT 468
IPRLD+VIS VG+VSSS LALI+P L+EI+ F E + + K+I I+ G++G + GT
Sbjct: 388 IPRLDLVISLVGSVSSSALALIIPALLEIVIFYSEDMSCVTIAKDIMISIVGLLGCIFGT 447
Query: 469 YITVEEIIYPTPKVVAGT 486
Y + E+ P +A +
Sbjct: 448 YQALYELPQPISHSMANS 465
>gi|222446642 solute carrier family 36, member 3 isoform 1 [Homo
sapiens]
Length = 511
Score = 405 bits (1040), Expect = e-113
Identities = 216/479 (45%), Positives = 300/479 (62%), Gaps = 59/479 (12%)
Query: 56 QEGISFVQTLMHLLKGNIGTGLLGLPLAIKNAGIVLGPISLVFIGIISVHCMHILVRCSH 115
+ G+S +QTL+HLLK NIGTGLLGLPLAIKNAG+++GP+SL+ IG+++VHCM IL+ C+
Sbjct: 39 EAGLSMMQTLIHLLKCNIGTGLLGLPLAIKNAGLLVGPVSLLAIGVLTVHCMVILLNCAQ 98
Query: 116 FLCLRFKKSTLGYSDTVSFAMEVSPWSCLQKQAAWGR----------------------- 152
L R +K+ + Y + + +E P + L+ A WGR
Sbjct: 99 HLSQRLQKTFVNYGEATMYGLETCPNTWLRAHAVWGRWNLALSPRLECSGKISAHCNPHL 158
Query: 153 ------------------SVVDFFLVITQLGFCSVYIVFLAENVKQVHEGFLESKVFISN 194
V F LVITQLGFCSVY +F+A+N++Q+ +
Sbjct: 159 QGSSNSPAQASRVAGIYRYTVSFLLVITQLGFCSVYFMFMADNLQQM----------VEK 208
Query: 195 STNSSNPCERRSV-------DLRIYMLCFLPFIILLVFIRELKNLFVLSFLANVSMAVSL 247
+ +SN C+ R + D+R YML LPF+ILLVFI+ LK L V S LAN++ S+
Sbjct: 209 AHVTSNICQPREILTLTPILDIRFYMLIILPFLILLVFIQNLKVLSVFSTLANITTLGSM 268
Query: 248 VIIYQYVVRNMPDPHNLPIVAGWKKYPLFFGTAVFAFEGIGVVLPLENQMKESKRFPQAL 307
+I++Y++ +P P NLP++A WK + LFFGTA+F FEG+G+VLPL+NQMK ++F L
Sbjct: 269 ALIFEYIMEGIPYPSNLPLMANWKTFLLFFGTAIFTFEGVGMVLPLKNQMKHPQQFSFVL 328
Query: 308 NIGMGIVTTLYVTLATLGYMCFHDEIKGSITLNLPQDVWLYQSVKILYSFGIFVTYSIQF 367
+GM IV LY+ L TLGYM F + + SITLNLP + WLYQSVK++YS GIF TY++QF
Sbjct: 329 YLGMSIVIILYILLGTLGYMKFGSDTQASITLNLP-NCWLYQSVKLMYSIGIFFTYALQF 387
Query: 368 YVPAEIIIPGITSKFHTKWKQICEFGIRSFLVSITCAGAILIPRLDIVISFVGAVSSSTL 427
+VPAEIIIP S+ W + +RS LV +TC AILIPRLD+VIS VG+VSSS L
Sbjct: 388 HVPAEIIIPFAISQVSESWALFVDLSVRSALVCLTCVSAILIPRLDLVISLVGSVSSSAL 447
Query: 428 ALILPPLVEILTFSKEHYNIWMVLKNISIAFTGVVGFLLGTYITVEEIIYPTPKVVAGT 486
ALI+P L+EI+ F E + + K+I I+ G++G + GTY + E+ P +A +
Sbjct: 448 ALIIPALLEIVIFYSEDMSCVTIAKDIMISIVGLLGCIFGTYQALYELPQPISHSMANS 506
>gi|24429574 solute carrier family 38, member 6 [Homo sapiens]
Length = 456
Score = 79.7 bits (195), Expect = 6e-15
Identities = 103/453 (22%), Positives = 185/453 (40%), Gaps = 50/453 (11%)
Query: 37 DEEHEQELLPVQKHYQLDDQE--GISFVQTLMHLLKGNIGTGLLGLPLAIKNAGIVLGPI 94
+E +EL P+ + +L Q G+SF ++ +L+ +G+G+LGL + N G+
Sbjct: 22 EEAEAEELSPLLSN-ELHRQRSPGVSFGLSVFNLMNAIMGSGILGLAYVMANTGVFGFSF 80
Query: 95 SLVFIGIISVHCMHILVRCSHFLCLRFKKSTLGYSDTVSFAMEVSPWSCLQKQAAWGRSV 154
L+ + +++ + +H+L L + + + Y D FA + G+ V
Sbjct: 81 LLLTVALLASYSVHLL------LSMCIQTAVTSYEDLGLFAFGLP-----------GKLV 123
Query: 155 VDFFLVITQLGFCSVYIVFLAENVKQVHEGFLESKV----FISNSTNSSNPCERRSVDLR 210
V ++I +G S Y++ + + FL ++ T C V +
Sbjct: 124 VAGTIIIQNIGAMSSYLLIIKTELPAAIAEFLTGDYSRYWYLDGQTLLIIIC----VGI- 178
Query: 211 IYMLCFLPFIILLVFIRELKNLFVLSFLANV-----SMAVSLVIIY---QYVVRNMPDPH 262
++ L LP I L + L F++ F V S+ L + Y + + N+ D
Sbjct: 179 VFPLALLPKIGFLGYTSSLSFFFMMFFALVVIIKKWSIPCPLTLNYVEKGFQISNVTDDC 238
Query: 263 NLPIVAGWKKYPLFFGTAVFAFEGIGVVLPL--ENQMKESKRFPQALNIGMGIVTTLYVT 320
+ K+ T F+F +LP+ E Q KR N + + +Y
Sbjct: 239 KPKLFHFSKESAYALPTMAFSFLCHTSILPIYCELQSPSKKRMQNVTNTAIALSFLIYFI 298
Query: 321 LATLGYMCFHDEIKGSI----TLNLPQDVWLYQSVKILYSFGIFVTYSIQFYVPAEIIIP 376
A GY+ F+D+++ + + L DV + +VK+ F + +T + + + +
Sbjct: 299 SALFGYLTFYDKVESELLKGYSKYLSHDV-VVMTVKLCILFAVLLTVPLIHFPARKAVTM 357
Query: 377 GITSKFHTKWKQICEFGIRSFLVSITCAGAILIPRLDIVISFVGAVSSSTLALILPPLVE 436
S F W I F I L I AI +P + V VGA +S+ L I P L
Sbjct: 358 MFFSNFPFSW--IRHFLITLALNIIIVLLAIYVPDIRNVFGVVGASTSTCLIFIFPGLF- 414
Query: 437 ILTFSKEHYNIWMVLKNISIAFTGVVGFLLGTY 469
L S+E + W K + + G L+G +
Sbjct: 415 YLKLSREDFLSW---KKLGAFVLLIFGILVGNF 444
>gi|17999520 solute carrier family 32, member 1 [Homo sapiens]
Length = 525
Score = 64.3 bits (155), Expect = 2e-10
Identities = 79/377 (20%), Positives = 147/377 (38%), Gaps = 42/377 (11%)
Query: 74 GTGLLGLPLAIKNAGIVLGPISLVFIGIISVHCMHILVRCSHFLCLRFKKSTLGYSDTVS 133
G +LGLP AI + G LG ++F ++ + IL+ C ++++ G V
Sbjct: 131 GMFVLGLPYAILHGGY-LGLFLIIFAAVVCCYTGKILIACL------YEENEDGEVVRVR 183
Query: 134 FA-MEVSPWSCLQKQAAWGRSVVDFFLVITQLGFCSVYIVFLAENVKQVHEGFLESKVFI 192
+ + ++ C + G VV+ +I + C +Y+V + G
Sbjct: 184 DSYVAIANACCAPRFPTLGGRVVNVAQIIELVMTCILYVVVSGNLMYNSFPGL------- 236
Query: 193 SNSTNSSNPCERRSVDLRIYMLCFLPFIILLVFIRELKNLFVLSFLANVSMAVSLVIIYQ 252
P ++S + I LP F++ LK + S L ++ V +++
Sbjct: 237 --------PVSQKSWSI-IATAVLLP----CAFLKNLKAVSKFSLLCTLAHFVINILVIA 283
Query: 253 YVVRNMPDP--HNLPIVAGWKKYPLFFGTAVFAFEGIGVVLPLENQMKESKRFPQALNIG 310
Y + D + KK+P+ G VF++ + LE M++ F +N
Sbjct: 284 YCLSRARDWAWEKVKFYIDVKKFPISIGIIVFSYTSQIFLPSLEGNMQQPSEFHCMMNWT 343
Query: 311 MGIVTTLYVTLATLGYMCFHDEIKGSITLNLPQDVWLYQSVKILYSFGIFVTYSIQFYVP 370
L A + Y+ + DE K IT NLP + V I ++Y + F+
Sbjct: 344 HIAACVLKGLFALVAYLTWADETKEVITDNLPGSI--RAVVNIFLVAKALLSYPLPFFAA 401
Query: 371 AEIIIPGITSKFHTKWKQICEFG----------IRSFLVSITCAGAILIPRLDIVISFVG 420
E++ + + + C G +R LV T AI +P +++ G
Sbjct: 402 VEVLEKSLFQEGSRAFFPACYSGDGRLKSWGLTLRCALVVFTLLMAIYVPHFALLMGLTG 461
Query: 421 AVSSSTLALILPPLVEI 437
+++ + L +LP L +
Sbjct: 462 SLTGAGLCFLLPSLFHL 478
>gi|193788624 solute carrier family 38, member 5 [Homo sapiens]
Length = 472
Score = 60.5 bits (145), Expect = 4e-09
Identities = 95/473 (20%), Positives = 183/473 (38%), Gaps = 89/473 (18%)
Query: 46 PVQKHYQLDDQEG-ISFVQTLMHLLKGNIGTGLLGLPLAIKNAGIVLGPISLVFIGIISV 104
P K Q D EG SF ++ +L +G+G+LGL A+ + G++ L+ I ++S
Sbjct: 34 PGSKPVQFMDFEGKTSFGMSVFNLSNAIMGSGILGLAYAMAHTGVIFFLALLLCIALLSS 93
Query: 105 HCMHILVRCSHFLCLRFKKSTLGYSDTVSFAMEVSPWSCLQKQAAWGRSVVDFFLVITQL 164
+ +H+L+ C+ +R Y A + G+ VV + + +
Sbjct: 94 YSIHLLLTCAGIAGIR------AYEQLGQRAFGPA-----------GKVVVATVICLHNV 136
Query: 165 GFCSVYIVFLAENVKQVHEGFL----ESKVFISNSTNSSNPCERRSVDLRIYMLCFLPFI 220
G S Y+ + + V FL E F+ + +L + +
Sbjct: 137 GAMSSYLFIIKSELPLVIGTFLYMDPEGDWFLKGN-----------------LLIIIVSV 179
Query: 221 ILLVFIRELKNLFVLSFLANVSMAVSLV----IIYQYVVRNMPDPHN-----------LP 265
++++ + +K+L L + + +S+ L +IY+ HN LP
Sbjct: 180 LIILPLALMKHLGYLGYTSGLSLTCMLFFLVSVIYKKFQLGCAIGHNETAMESEALVGLP 239
Query: 266 -------------IVAGWKKYPLFFGTAVFAFEGIGVVLPLENQM-KESKRFPQAL-NIG 310
V Y + FAF VLP+ ++ + SKR QA+ N+
Sbjct: 240 SQGLNSSCEAQMFTVDSQMSYTV--PIMAFAFVCHPEVLPIYTELCRPSKRRMQAVANVS 297
Query: 311 MGIVTTLYVTLATLGYMCFHDEIKGSITLNLPQDVWLYQSVKILYSFGIFVTYSIQFY-- 368
+G + +Y AT GY+ F+ +K + Q L V++ + +T + +
Sbjct: 298 IGAMFCMYGLTATFGYLTFYSSVKAEMLHMYSQKDPLILCVRLAVLLAVTLTVPVVLFPI 357
Query: 369 --VPAEIIIPGITSKFHTKWKQICEFGIRSFLVSITCAGAILIPRLDIVISFVGAVSSST 426
+++ PG W + I L+ + I +P + + +G+ S+ +
Sbjct: 358 RRALQQLLFPGKA----FSWPR--HVAIALILLVLVNVLVICVPTIRDIFGVIGSTSAPS 411
Query: 427 LALILPPL--VEILTFSKEHYNIWMVLKNISIAFTGV------VGFLLGTYIT 471
L ILP + + I+ E + W ++ + GV +GF+ + T
Sbjct: 412 LIFILPSIFYLRIVPSEVEPFLSWPKIQALCFGVLGVLFMAVSLGFMFANWAT 464
>gi|117168277 amino acid transporter system A1 [Homo sapiens]
Length = 487
Score = 58.2 bits (139), Expect = 2e-08
Identities = 83/396 (20%), Positives = 157/396 (39%), Gaps = 56/396 (14%)
Query: 60 SFVQTLMHLLKGNIGTGLLGLPLAIKNAGIVLGPISLVFIGIISVHCMHILVRCSHFL-C 118
S ++ +L +G+G+LGL A+ N GI+L + L + ++S++ +++L+ CS C
Sbjct: 72 SLGMSVFNLSNAIMGSGILGLAFALANTGILLFLVLLTSVTLLSIYSINLLLICSKETGC 131
Query: 119 LRFKKSTLGYSDTVSFAMEVSPWSCLQKQAAWGRSVVDFFLVITQLGFCSVYIVFLAENV 178
+ ++K LG Q G+ V+ + G Y+ F+ +N
Sbjct: 132 MVYEK--LGE----------------QVFGTTGKFVIFGATSLQNTGAMLSYL-FIVKNE 172
Query: 179 KQVHEGFLESKVFISNSTNSSNPCERRSVDLRIYMLCFLPFIILLVFIRELKNLFVLSFL 238
FL K VD R+ ++ IIL + + LKNL L +
Sbjct: 173 LPSAIKFLMGK---------EETFSAWYVDGRVLVVIVTFGIILPLCL--LKNLGYLGYT 221
Query: 239 ANVSMAVSLVIIYQYVVRNMPDPHNLPIVAGW------------KKYPLFFGTAVFAFEG 286
+ S++ + + + + P +P + KY F V+A
Sbjct: 222 SGFSLSCMVFFLIVVIYKKFQIPCIVPELNSTISANSTNADTCTPKYVTFNSKTVYALPT 281
Query: 287 IGV-------VLPLENQMKE--SKRFPQALNIGMGIVTTLYVTLATLGYMCFHDEIKGSI 337
I VLP+ +++K+ K+ NI + +Y A GY+ F+D ++ +
Sbjct: 282 IAFAFVCHPSVLPIYSELKDRSQKKMQMVSNISFFAMFVMYFLTAIFGYLTFYDNVQSDL 341
Query: 338 TLNL-PQDVWLYQSVKILYSFGIFVTYSIQFYVPAEIIIPGITSKFHTKWKQICEFGIRS 396
+D L +V++ + +T + F+ + + K TK+ +
Sbjct: 342 LHKYQSKDDILILTVRLAVIVAVILTVPVLFFTVRSSLFE-LAKK--TKFNLCRHTVVTC 398
Query: 397 FLVSITCAGAILIPRLDIVISFVGAVSSSTLALILP 432
L+ + I IP + + VG S++ L ILP
Sbjct: 399 ILLVVINLLVIFIPSMKDIFGVVGVTSANMLIFILP 434
>gi|117168275 amino acid transporter system A1 [Homo sapiens]
Length = 487
Score = 58.2 bits (139), Expect = 2e-08
Identities = 83/396 (20%), Positives = 157/396 (39%), Gaps = 56/396 (14%)
Query: 60 SFVQTLMHLLKGNIGTGLLGLPLAIKNAGIVLGPISLVFIGIISVHCMHILVRCSHFL-C 118
S ++ +L +G+G+LGL A+ N GI+L + L + ++S++ +++L+ CS C
Sbjct: 72 SLGMSVFNLSNAIMGSGILGLAFALANTGILLFLVLLTSVTLLSIYSINLLLICSKETGC 131
Query: 119 LRFKKSTLGYSDTVSFAMEVSPWSCLQKQAAWGRSVVDFFLVITQLGFCSVYIVFLAENV 178
+ ++K LG Q G+ V+ + G Y+ F+ +N
Sbjct: 132 MVYEK--LGE----------------QVFGTTGKFVIFGATSLQNTGAMLSYL-FIVKNE 172
Query: 179 KQVHEGFLESKVFISNSTNSSNPCERRSVDLRIYMLCFLPFIILLVFIRELKNLFVLSFL 238
FL K VD R+ ++ IIL + + LKNL L +
Sbjct: 173 LPSAIKFLMGK---------EETFSAWYVDGRVLVVIVTFGIILPLCL--LKNLGYLGYT 221
Query: 239 ANVSMAVSLVIIYQYVVRNMPDPHNLPIVAGW------------KKYPLFFGTAVFAFEG 286
+ S++ + + + + P +P + KY F V+A
Sbjct: 222 SGFSLSCMVFFLIVVIYKKFQIPCIVPELNSTISANSTNADTCTPKYVTFNSKTVYALPT 281
Query: 287 IGV-------VLPLENQMKE--SKRFPQALNIGMGIVTTLYVTLATLGYMCFHDEIKGSI 337
I VLP+ +++K+ K+ NI + +Y A GY+ F+D ++ +
Sbjct: 282 IAFAFVCHPSVLPIYSELKDRSQKKMQMVSNISFFAMFVMYFLTAIFGYLTFYDNVQSDL 341
Query: 338 TLNL-PQDVWLYQSVKILYSFGIFVTYSIQFYVPAEIIIPGITSKFHTKWKQICEFGIRS 396
+D L +V++ + +T + F+ + + K TK+ +
Sbjct: 342 LHKYQSKDDILILTVRLAVIVAVILTVPVLFFTVRSSLFE-LAKK--TKFNLCRHTVVTC 398
Query: 397 FLVSITCAGAILIPRLDIVISFVGAVSSSTLALILP 432
L+ + I IP + + VG S++ L ILP
Sbjct: 399 ILLVVINLLVIFIPSMKDIFGVVGVTSANMLIFILP 434
>gi|5870893 solute carrier family 38, member 3 [Homo sapiens]
Length = 504
Score = 57.0 bits (136), Expect = 4e-08
Identities = 91/466 (19%), Positives = 178/466 (38%), Gaps = 78/466 (16%)
Query: 46 PVQKHYQLDDQEGISFVQTLMHLLKGNIGTGLLGLPLAIKNAGIVLGPISLVFIGIISVH 105
P ++ + D + SF ++ +L +G+G+LGL A+ N GI+L L + ++S +
Sbjct: 53 PSKEPHFTDFEGKTSFGMSVFNLSNAIMGSGILGLAYAMANTGIILFLFLLTAVALLSSY 112
Query: 106 CMHILVRCSHFLCLRFKKSTLGYSDTVSFAMEVSPWSCLQKQAAWGRSVVDFFLVITQLG 165
+H+L++ S + +R + LGY + G+ + + +G
Sbjct: 113 SIHLLLKSSGVVGIRAYEQ-LGY----------------RAFGTPGKLAAALAITLQNIG 155
Query: 166 FCSVYIVFLAENVKQVHEGFLESKVFISNSTNSSNPCERRSVDLRIYMLCFLPFIILLVF 225
S Y+ + + V + FL + S+ + N + +L + I+ L
Sbjct: 156 AMSSYLYIIKSELPLVIQTFLNLEEKTSDWYMNGN---------YLVILVSVTIILPLAL 206
Query: 226 IRELKNL-FVLSFLANVSMAVSLVIIYQYVVRNMPDPHNLPIVAGWKKY----------- 273
+R+L L + F + + + +IY+ P P N G +
Sbjct: 207 MRQLGYLGYSSGFSLSCMVFFLIAVIYKKFHVPCPLPPNFNNTTGNFSHVEIVKEKVQLQ 266
Query: 274 ----------PLFF----------GTAVFAFEGIGVVLPLENQMKE--SKRFPQALNIGM 311
P +F FAF VLP+ ++K+ K+ N+ +
Sbjct: 267 VEPEASAFCTPSYFTLNSQTAYTIPIMAFAFVCHPEVLPIYTELKDPSKKKMQHISNLSI 326
Query: 312 GIVTTLYVTLATLGYMCFHDEIKGSITLNL----PQDVWLYQSVKILYSFGIFVTYSIQF 367
++ +Y A GY+ F++ ++ + P DV L V++ + +T I
Sbjct: 327 AVMYIMYFLAALFGYLTFYNGVESELLHTYSKVDPFDV-LILCVRVAVLTAVTLTVPIVL 385
Query: 368 YVPAEIIIPGITSKFHTKWKQICEFGIRSFLVSI---TCAGAILI--PRLDIVISFVGAV 422
+ I + W +R L+++ TC ++I P + + +GA
Sbjct: 386 FPVRRAIQQMLFPNQEFSW-------LRHVLIAVGLLTCINLLVIFAPNILGIFGVIGAT 438
Query: 423 SSSTLALILPPLVEILTFSKEHYNIWMVLKNISIAFTGVVGFLLGT 468
S+ L I P + E K +++ F ++GFLL T
Sbjct: 439 SAPFLIFIFPAIFYFRIMPTEKEPARSTPKILALCF-AMLGFLLMT 483
>gi|219689132 solute carrier family 38, member 4 [Homo sapiens]
Length = 547
Score = 54.3 bits (129), Expect = 3e-07
Identities = 49/210 (23%), Positives = 94/210 (44%), Gaps = 17/210 (8%)
Query: 281 VFAFEGIGVVLPLENQMKE-SKRFPQAL-NIGMGIVTTLYVTLATLGYMCFHDEIKGSI- 337
VFAF VLP+ +++K+ S+R Q + NI + + +Y+ A GY+ F+ E++ +
Sbjct: 340 VFAFVCHPEVLPIYSELKDRSRRKMQTVSNISITGMLVMYLLAALFGYLTFYGEVEDELL 399
Query: 338 -------TLNLPQDVWLYQSVKILYSFGIFVTYSIQFYVPAEIIIPGITSKFHTKWKQIC 390
TL++P V++ + +T I + +I + K W I
Sbjct: 400 HAYSKVYTLDIP-----LLMVRLAVLVAVTLTVPIVLFPIRTSVITLLFPKRPFSW--IR 452
Query: 391 EFGIRSFLVSITCAGAILIPRLDIVISFVGAVSSSTLALILPPLVEILTFSKEHYNIWMV 450
F I + L+++ IL+P + + F+GA S++ L ILP + + KE +
Sbjct: 453 HFLIAAVLIALNNVLVILVPTIKYIFGFIGASSATMLIFILPAVFYLKLVKKETFRSPQK 512
Query: 451 LKNISIAFTGVVGFLLGTYITVEEIIYPTP 480
+ + G+ + + + + IY P
Sbjct: 513 VGALIFLVVGIFFMIGSMALIIIDWIYDPP 542
Score = 42.7 bits (99), Expect = 8e-04
Identities = 44/209 (21%), Positives = 88/209 (42%), Gaps = 31/209 (14%)
Query: 60 SFVQTLMHLLKGNIGTGLLGLPLAIKNAGIVLGPISLVFIGIISVHCMHILVRCSHFLCL 119
SF + +L +G+G+LGL A+ N GI+L I L+ + I+S++ +H+L++ +
Sbjct: 76 SFGMSSFNLSNAIMGSGILGLSYAMANTGIILFIIMLLAVAILSLYSVHLLLKTAK---- 131
Query: 120 RFKKSTLGYSDTVSFAMEVSPWSCLQKQAAWGRSVVDFFLVITQ-LGFCSVYIVFLAENV 178
+ +L Y +K W + F + Q +G S Y+ + +
Sbjct: 132 --EGGSLIYE------------KLGEKAFGWPGKIGAFVSITMQNIGAMSSYLFIIKYEL 177
Query: 179 KQVHEGFLESKVFISNSTNSSNPCERRSVDLRIYMLCFLPFIILLVFIRELKNLFVLSFL 238
+V F+ + + N Y++ F+ I+L + LKNL L +
Sbjct: 178 PEVIRAFMGLEENTGEWYLNGN-----------YLIIFVSVGIILP-LSLLKNLGYLGYT 225
Query: 239 ANVSMAVSLVIIYQYVVRNMPDPHNLPIV 267
+ S+ + + + + P LP++
Sbjct: 226 SGFSLTCMVFFVSVVIYKKFQIPCPLPVL 254
>gi|18482385 solute carrier family 38, member 4 [Homo sapiens]
Length = 547
Score = 54.3 bits (129), Expect = 3e-07
Identities = 49/210 (23%), Positives = 94/210 (44%), Gaps = 17/210 (8%)
Query: 281 VFAFEGIGVVLPLENQMKE-SKRFPQAL-NIGMGIVTTLYVTLATLGYMCFHDEIKGSI- 337
VFAF VLP+ +++K+ S+R Q + NI + + +Y+ A GY+ F+ E++ +
Sbjct: 340 VFAFVCHPEVLPIYSELKDRSRRKMQTVSNISITGMLVMYLLAALFGYLTFYGEVEDELL 399
Query: 338 -------TLNLPQDVWLYQSVKILYSFGIFVTYSIQFYVPAEIIIPGITSKFHTKWKQIC 390
TL++P V++ + +T I + +I + K W I
Sbjct: 400 HAYSKVYTLDIP-----LLMVRLAVLVAVTLTVPIVLFPIRTSVITLLFPKRPFSW--IR 452
Query: 391 EFGIRSFLVSITCAGAILIPRLDIVISFVGAVSSSTLALILPPLVEILTFSKEHYNIWMV 450
F I + L+++ IL+P + + F+GA S++ L ILP + + KE +
Sbjct: 453 HFLIAAVLIALNNVLVILVPTIKYIFGFIGASSATMLIFILPAVFYLKLVKKETFRSPQK 512
Query: 451 LKNISIAFTGVVGFLLGTYITVEEIIYPTP 480
+ + G+ + + + + IY P
Sbjct: 513 VGALIFLVVGIFFMIGSMALIIIDWIYDPP 542
Score = 42.7 bits (99), Expect = 8e-04
Identities = 44/209 (21%), Positives = 88/209 (42%), Gaps = 31/209 (14%)
Query: 60 SFVQTLMHLLKGNIGTGLLGLPLAIKNAGIVLGPISLVFIGIISVHCMHILVRCSHFLCL 119
SF + +L +G+G+LGL A+ N GI+L I L+ + I+S++ +H+L++ +
Sbjct: 76 SFGMSSFNLSNAIMGSGILGLSYAMANTGIILFIIMLLAVAILSLYSVHLLLKTAK---- 131
Query: 120 RFKKSTLGYSDTVSFAMEVSPWSCLQKQAAWGRSVVDFFLVITQ-LGFCSVYIVFLAENV 178
+ +L Y +K W + F + Q +G S Y+ + +
Sbjct: 132 --EGGSLIYE------------KLGEKAFGWPGKIGAFVSITMQNIGAMSSYLFIIKYEL 177
Query: 179 KQVHEGFLESKVFISNSTNSSNPCERRSVDLRIYMLCFLPFIILLVFIRELKNLFVLSFL 238
+V F+ + + N Y++ F+ I+L + LKNL L +
Sbjct: 178 PEVIRAFMGLEENTGEWYLNGN-----------YLIIFVSVGIILP-LSLLKNLGYLGYT 225
Query: 239 ANVSMAVSLVIIYQYVVRNMPDPHNLPIV 267
+ S+ + + + + P LP++
Sbjct: 226 SGFSLTCMVFFVSVVIYKKFQIPCPLPVL 254
>gi|83921602 solute carrier family 38, member 10 isoform a [Homo
sapiens]
Length = 1119
Score = 51.6 bits (122), Expect = 2e-06
Identities = 82/442 (18%), Positives = 170/442 (38%), Gaps = 69/442 (15%)
Query: 65 LMHLLKGNIGTGLLGLPLAIKNAGIVLGPISLVFIGIISVHCMHILVRCSHFLCLRFKKS 124
+ +++ +G +L +P K GIVLG + LVF ++ LV+ + L +++
Sbjct: 12 ITNIVNSIVGVSVLTMPFCFKQCGIVLGALLLVFCSWMTHQSCMFLVKSAS---LSKRRT 68
Query: 125 TLGYSDTVSFAMEVSPWSCLQKQAAWGRSVVDFFLVITQLGFCSVYIVFLAE---NVKQV 181
G + G+ +V+ ++ LG C + V + + N
Sbjct: 69 YAGLA--------------FHAYGKAGKMLVETSMIGLMLGTCIAFYVVIGDLGSNFFAR 114
Query: 182 HEGFLESKVFISNSTNSSNPCERRSVDLRIYMLCFLPFIILLVFIRELKNLFVLSFLANV 241
GF F R+++L + I+L L+ + S +
Sbjct: 115 LFGFQVGGTF------------------RMFLLFAVSLCIVLPL--SLQRNMMASIQSFS 154
Query: 242 SMAVSLVIIYQYVVRNMPDPHNLPIVAGWKKYPLFFGTAVF--------AFEGIGVVLPL 293
+MA+ ++ +V+ H L ++ VF +F VLP
Sbjct: 155 AMALLFYTVFMFVIVLSSLKHGLFSGQWLRRVSYVRWEGVFRCIPIFGMSFACQSQVLPT 214
Query: 294 ENQMKES--KRFPQALNIGMGIVTTLYVTLATLGYMCFHDEIKGSITLNLPQDVWLYQSV 351
+ + E K + +VTT YV + GY+ F + G++ ++ P ++ + + +
Sbjct: 215 YDSLDEPSVKTMSSIFASSLNVVTTFYVMVGFFGYVSFTEATAGNVLMHFPSNL-VTEML 273
Query: 352 KILYSFGIFVTYSIQFYVPAEIIIPGITSKFHTKWKQICEFG------IRSFLVSI---T 402
++ + + V + + +P + + + K G ++ +S+ T
Sbjct: 274 RVGFMMSVAVGFPMMI-LPCRQALSTLLCEQQQKDGTFAAGGYMPPLRFKALTLSVVFGT 332
Query: 403 CAGAILIPRLDIVISFVGAVSSSTLALILPPLVEILTFSKEHYNIWMVLKNISIAFTGVV 462
G ILIP ++ ++ GA S + I P L+ + K H N L + + + G +
Sbjct: 333 MVGGILIPNVETILGLTGATMGSLICFICPALI----YKKIHKN---ALSSQVVLWVG-L 384
Query: 463 GFLLGTYITVEEIIYPTPKVVA 484
G L+ + +T + P+ +A
Sbjct: 385 GVLVVSTVTTLSVSEEVPEDLA 406
>gi|20070376 solute carrier family 38, member 10 isoform b [Homo
sapiens]
Length = 780
Score = 51.6 bits (122), Expect = 2e-06
Identities = 82/442 (18%), Positives = 170/442 (38%), Gaps = 69/442 (15%)
Query: 65 LMHLLKGNIGTGLLGLPLAIKNAGIVLGPISLVFIGIISVHCMHILVRCSHFLCLRFKKS 124
+ +++ +G +L +P K GIVLG + LVF ++ LV+ + L +++
Sbjct: 12 ITNIVNSIVGVSVLTMPFCFKQCGIVLGALLLVFCSWMTHQSCMFLVKSAS---LSKRRT 68
Query: 125 TLGYSDTVSFAMEVSPWSCLQKQAAWGRSVVDFFLVITQLGFCSVYIVFLAE---NVKQV 181
G + G+ +V+ ++ LG C + V + + N
Sbjct: 69 YAGLA--------------FHAYGKAGKMLVETSMIGLMLGTCIAFYVVIGDLGSNFFAR 114
Query: 182 HEGFLESKVFISNSTNSSNPCERRSVDLRIYMLCFLPFIILLVFIRELKNLFVLSFLANV 241
GF F R+++L + I+L L+ + S +
Sbjct: 115 LFGFQVGGTF------------------RMFLLFAVSLCIVLPL--SLQRNMMASIQSFS 154
Query: 242 SMAVSLVIIYQYVVRNMPDPHNLPIVAGWKKYPLFFGTAVF--------AFEGIGVVLPL 293
+MA+ ++ +V+ H L ++ VF +F VLP
Sbjct: 155 AMALLFYTVFMFVIVLSSLKHGLFSGQWLRRVSYVRWEGVFRCIPIFGMSFACQSQVLPT 214
Query: 294 ENQMKES--KRFPQALNIGMGIVTTLYVTLATLGYMCFHDEIKGSITLNLPQDVWLYQSV 351
+ + E K + +VTT YV + GY+ F + G++ ++ P ++ + + +
Sbjct: 215 YDSLDEPSVKTMSSIFASSLNVVTTFYVMVGFFGYVSFTEATAGNVLMHFPSNL-VTEML 273
Query: 352 KILYSFGIFVTYSIQFYVPAEIIIPGITSKFHTKWKQICEFG------IRSFLVSI---T 402
++ + + V + + +P + + + K G ++ +S+ T
Sbjct: 274 RVGFMMSVAVGFPMMI-LPCRQALSTLLCEQQQKDGTFAAGGYMPPLRFKALTLSVVFGT 332
Query: 403 CAGAILIPRLDIVISFVGAVSSSTLALILPPLVEILTFSKEHYNIWMVLKNISIAFTGVV 462
G ILIP ++ ++ GA S + I P L+ + K H N L + + + G +
Sbjct: 333 MVGGILIPNVETILGLTGATMGSLICFICPALI----YKKIHKN---ALSSQVVLWVG-L 384
Query: 463 GFLLGTYITVEEIIYPTPKVVA 484
G L+ + +T + P+ +A
Sbjct: 385 GVLVVSTVTTLSVSEEVPEDLA 406
>gi|222418629 solute carrier family 38, member 9 [Homo sapiens]
Length = 561
Score = 47.0 bits (110), Expect = 4e-05
Identities = 79/456 (17%), Positives = 164/456 (35%), Gaps = 73/456 (16%)
Query: 64 TLMHLLKGNIGTGLLGLPLAIKNAGIVLGPISLVFIGIISVHCMHILVRCSHFLCLRFKK 123
T+ + +GT +L +P IK AG G ++ +G+++++C + +V+
Sbjct: 122 TIFMIWNTMMGTSILSIPWGIKQAGFTTGMCVIILMGLLTLYCCYRVVK----------- 170
Query: 124 STLGYSDTVSFAMEVSPWS----CLQKQAAWGRSVVDFFLVITQLGFCSVYIVFLAENVK 179
S T+ F+++ + W C ++G+ F +++ +G VY V ++ +
Sbjct: 171 -----SRTMMFSLDTTSWEYPDVCRHYFGSFGQWSSLLFSLVSLIGAMIVYWVLMSNFLF 225
Query: 180 QVHEGFLESKVFISN-----STNSSNPC----------------------------ERRS 206
+ I++ STN+SNP E+
Sbjct: 226 NTGKFIFNFIHHINDTDTILSTNNSNPVICPSAGSGGHPDNSSMIFYANDTGAQQFEKWW 285
Query: 207 VDLRIYMLCFLPFIILLVFIRELKNLFVLSFLANVSMAVSLVIIYQYVVR---------N 257
R + ++ L+ + + L VS+ + ++ VR
Sbjct: 286 DKSRTVPFYLVGLLLPLLNFKSPSFFSKFNILGTVSVLYLIFLVTFKAVRLGFHLEFHWF 345
Query: 258 MPDPHNLPIVAGWKKYPLFFGTAVFAFEGIGVVLPLENQMKESKRFPQALNIGMGIVTTL 317
+P +P + ++P G AF ++ L K+ + + L I +VT
Sbjct: 346 IPTEFFVPEIR--FQFPQLTGVLTLAFFIHNCIITLLKNNKKQENNVRDLCIAYMLVTLT 403
Query: 318 YVTLATLGYMCF------HDEIKGSITLNLPQDVWLYQSVKILYSFGIFVTYSIQFYVPA 371
Y+ + L + F D I+ + N P L +I F + Y + Y+
Sbjct: 404 YLYIGVLVFASFPSPPLSKDCIEQNFLDNFPSSDTLSFIARIFLLFQMMTVYPLLGYLAR 463
Query: 372 EIIIPGITSKFHTKWKQICEFGIRSFLVSITCAGAILIPRLDIVISFVGAVSSSTLALIL 431
++ I + + + +V A P + +I + GA I
Sbjct: 464 VQLLGHIFGDIYPSIFHVLILNL--IIVGAGVIMACFYPNIGGIIRYSGAACGLAFVFIY 521
Query: 432 PPLVEILTFSKEHYNIW-MVLKNISIAFTGVVGFLL 466
P L+ I++ +E W ++ ++ I GV ++
Sbjct: 522 PSLIYIISLHQEERLTWPKLIFHVFIIILGVANLIV 557
>gi|21361602 solute carrier family 38, member 2 [Homo sapiens]
Length = 506
Score = 45.4 bits (106), Expect = 1e-04
Identities = 27/83 (32%), Positives = 48/83 (57%), Gaps = 4/83 (4%)
Query: 37 DEEHEQELLPV---QKHYQLDDQEGI-SFVQTLMHLLKGNIGTGLLGLPLAIKNAGIVLG 92
D E++ LL +K Y+ + G SF ++ +L +G+G+LGL A+ N GI L
Sbjct: 45 DPENQNFLLESNLGKKKYETEFHPGTTSFGMSVFNLSNAIVGSGILGLSYAMANTGIALF 104
Query: 93 PISLVFIGIISVHCMHILVRCSH 115
I L F+ I S++ +H+L++ ++
Sbjct: 105 IILLTFVSIFSLYSVHLLLKTAN 127
Score = 38.9 bits (89), Expect = 0.011
Identities = 36/170 (21%), Positives = 73/170 (42%), Gaps = 11/170 (6%)
Query: 281 VFAFEGIGVVLPLENQMKES--KRFPQALNIGMGIVTTLYVTLATLGYMCFHDEIKGSIT 338
+F+F VLP+ ++K+ +R I + +Y+ A GY+ F++ ++ +
Sbjct: 300 IFSFVCHPAVLPIYEELKDRSRRRMMNVSKISFFAMFLMYLLAALFGYLTFYEHVESELL 359
Query: 339 LN----LPQDVWLYQSVKILYSFGIFVTYSIQFY-VPAEIIIPGITSKFHTKWKQICEFG 393
L D+ L V++ + +T + + + + + SK + W+
Sbjct: 360 HTYSSILGTDILLL-IVRLAVLMAVTLTVPVVIFPIRSSVTHLLCASKDFSWWRHSL--- 415
Query: 394 IRSFLVSITCAGAILIPRLDIVISFVGAVSSSTLALILPPLVEILTFSKE 443
I +++ T I +P + + F+GA ++S L ILP I KE
Sbjct: 416 ITVSILAFTNLLVIFVPTIRDIFGFIGASAASMLIFILPSAFYIKLVKKE 465
>gi|27735137 solute carrier family 38, member 11 [Homo sapiens]
Length = 384
Score = 38.5 bits (88), Expect = 0.014
Identities = 28/126 (22%), Positives = 58/126 (46%), Gaps = 5/126 (3%)
Query: 309 IGMGIVTTLYVTL--ATLGYMCFHDEIKGSITLNLPQDVWLYQSVKILYSFGIFVTYSIQ 366
I M IV ++++ + AT GY+ F +G + N ++ L + Y + +TY ++
Sbjct: 178 IHMSIVISVFICIFFATCGYLTFTGFTQGDLFENYCRNDDLVTFGRFCYGVTVILTYPME 237
Query: 367 FYVPAEIIIPGITSKFHTKWKQICEFGIRSFLVSITCAGAILIPRLDIVISFVGAVSSST 426
+V E+I F + + ++++ ++LI L IV+ G + ++
Sbjct: 238 CFVTREVI---ANVFFGGNLSSVFHIVVTVMVITVATLVSLLIDCLGIVLELNGVLCATP 294
Query: 427 LALILP 432
L I+P
Sbjct: 295 LIFIIP 300
>gi|198041678 solute carrier family 12 (potassium-chloride
transporter), member 5 isoform 1 [Homo sapiens]
Length = 1139
Score = 33.9 bits (76), Expect = 0.36
Identities = 21/60 (35%), Positives = 34/60 (56%), Gaps = 3/60 (5%)
Query: 208 DLRIYMLCFLPFIILLVFIR-ELKNLFVLSFLANVSMAVSLVIIYQYVVRNMPDPHNLPI 266
++R+Y C L + +VF+ + N F L FL V + S++ IY V+++ DP N PI
Sbjct: 252 NMRVYGTCVLTCMATVVFVGVKYVNKFALVFLGCVIL--SILAIYAGVIKSAFDPPNFPI 309
>gi|11968148 solute carrier family 12 (potassium-chloride
transporter), member 5 isoform 2 [Homo sapiens]
Length = 1116
Score = 33.9 bits (76), Expect = 0.36
Identities = 21/60 (35%), Positives = 34/60 (56%), Gaps = 3/60 (5%)
Query: 208 DLRIYMLCFLPFIILLVFIR-ELKNLFVLSFLANVSMAVSLVIIYQYVVRNMPDPHNLPI 266
++R+Y C L + +VF+ + N F L FL V + S++ IY V+++ DP N PI
Sbjct: 229 NMRVYGTCVLTCMATVVFVGVKYVNKFALVFLGCVIL--SILAIYAGVIKSAFDPPNFPI 286
>gi|123701900 solute carrier family 12 (potassium/chloride
transporters), member 7 [Homo sapiens]
Length = 1083
Score = 33.9 bits (76), Expect = 0.36
Identities = 20/60 (33%), Positives = 36/60 (60%), Gaps = 3/60 (5%)
Query: 208 DLRIYMLCFLPFIILLVFIR-ELKNLFVLSFLANVSMAVSLVIIYQYVVRNMPDPHNLPI 266
++R+Y C L + L+VF+ + N L FLA V +S++ IY V+++ DP ++P+
Sbjct: 250 NMRVYGTCTLVLMALVVFVGVKYVNKLALVFLACV--VLSILAIYAGVIKSAFDPPDIPV 307
>gi|157388943 transmembrane protein 104 [Homo sapiens]
Length = 496
Score = 32.3 bits (72), Expect = 1.0
Identities = 81/423 (19%), Positives = 156/423 (36%), Gaps = 57/423 (13%)
Query: 65 LMHLLKGNIGTGLLGLPLAIKNAGIVLGPISLVFIGIIS-------VHCMHILVRCSHFL 117
L+++ +GTG L +P A AG ++ + LVF+G +S + M H+
Sbjct: 18 LVYMFNLIVGTGALTMPKAFATAGWLVSLVLLVFLGFMSFVTTTFVIEAMAAANAQLHWK 77
Query: 118 CLRFKK-------STLGYSDTV----SFAMEVSPWSCLQKQAA----------------- 149
+ K ST SD + E P +Q++ +
Sbjct: 78 RMENLKEEEDDDSSTASDSDVLIRDNYERAEKRPILSVQRRGSPNPFEITDRVEMGQMAS 137
Query: 150 -----WGRSVVDFFLVITQLGFCSVYIVFLAENVKQV---HEGFLESKVFISNSTNSSNP 201
G ++ F +++ G ++Y + ++ QV G V N ++
Sbjct: 138 MFFNKVGVNLFYFCIIVYLYGDLAIYAAAVPFSLMQVTCSATGNDSCGVEADTKYNDTDR 197
Query: 202 C---ERRSVDLRIYMLCFLPFIILLVF--IRELKNLFVLSFLAN-VSMAVSLVIIYQYVV 255
C RR RIY+ F + F +++ K L +L+ L ++ AV +V+ +
Sbjct: 198 CWGPLRRVDAYRIYLAIFTLLLGPFTFFDVQKTKYLQILTSLMRWIAFAVMIVLALIRIG 257
Query: 256 RNMPDPHNLPIVAGWKKYPLFFGTAVFAFEGIGVVLPLENQMKESKRFPQALNIGMGIVT 315
+ H P +A + FG V++F + L + + + + + ++
Sbjct: 258 HGQGEGH--PPLADFSGVRNLFGVCVYSFMCQHSLPSLITPVSSKRHLTRLVFLDYVLIL 315
Query: 316 TLYVTLATLGYMCFH-DEIKGSITLNLPQ-DVWLYQSVKILYSFGIFVTYSIQFYVPAEI 373
Y L+ CF D + TLN + DV +V+ T S F + A
Sbjct: 316 AFYGLLSFTAIFCFRGDSLMDMYTLNFARCDVVGLAAVRFFLGLFPVFTISTNFPIIAVT 375
Query: 374 IIPGITSKFHTKWKQICEFGIRSFLVSITCAGAILIP----RLDIVISFVGAVSSSTLAL 429
+ + FH + R +IT +L+ L+ ++ GA + + +
Sbjct: 376 LRNNWKTLFHREGGTYPWVVDRVVFPTITLVPPVLVAFCTHDLESLVGITGAYAGTGIQY 435
Query: 430 ILP 432
++P
Sbjct: 436 VIP 438
>gi|5729798 cysteinyl leukotriene receptor 1 [Homo sapiens]
Length = 337
Score = 32.0 bits (71), Expect = 1.4
Identities = 36/148 (24%), Positives = 66/148 (44%), Gaps = 14/148 (9%)
Query: 275 LFFGTAVFAFEGIGVVLPLENQMKESKRFPQALNIGMGIVTTLYVTLATLGYMCF---HD 331
+FF TA+ F I +V P++N +++ + + +G+ I +V L + ++ D
Sbjct: 111 IFFMTAMSFFRCIAIVFPVQNINLVTQKKARFVCVGIWI----FVILTSSPFLMAKPQKD 166
Query: 332 EIKGSITLNLPQDVWLYQSVKILYSFGIFVTYSIQFYVPAEIIIPGITSKFHTKWKQICE 391
E + PQD V +L+ +FV F +P III T T K+ +
Sbjct: 167 EKNNTKCFEPPQDNQTKNHVLVLHYVSLFV----GFIIPFVIIIVCYTMIILTLLKKSMK 222
Query: 392 FGIRSFLVSITCAGAILIPRLDIVISFV 419
+ S +I G I++ ++SF+
Sbjct: 223 KNLSSHKKAI---GMIMVVTAAFLVSFM 247
>gi|110224458 solute carrier family 12, member 6 isoform e [Homo
sapiens]
Length = 1135
Score = 32.0 bits (71), Expect = 1.4
Identities = 27/106 (25%), Positives = 47/106 (44%), Gaps = 19/106 (17%)
Query: 164 LGFCSVYIVFLAENVKQVH--EGFLESKVFISNSTNSSNPCERRSVDLRIYMLCFLPFII 221
LG +++V++ H + ES ++N +R+Y FL ++
Sbjct: 270 LGAIEIFLVYIVPRAAIFHSDDALKESAAMLNN--------------MRVYGTAFLVLMV 315
Query: 222 LLVFIR-ELKNLFVLSFLANVSMAVSLVIIYQYVVRNMPDPHNLPI 266
L+VFI N F FLA V VS++ IY +++ P + P+
Sbjct: 316 LVVFIGVRYVNKFASLFLACV--IVSILAIYAGAIKSSFAPPHFPV 359
>gi|110224456 solute carrier family 12, member 6 isoform d [Homo
sapiens]
Length = 1141
Score = 32.0 bits (71), Expect = 1.4
Identities = 27/106 (25%), Positives = 47/106 (44%), Gaps = 19/106 (17%)
Query: 164 LGFCSVYIVFLAENVKQVH--EGFLESKVFISNSTNSSNPCERRSVDLRIYMLCFLPFII 221
LG +++V++ H + ES ++N +R+Y FL ++
Sbjct: 276 LGAIEIFLVYIVPRAAIFHSDDALKESAAMLNN--------------MRVYGTAFLVLMV 321
Query: 222 LLVFIR-ELKNLFVLSFLANVSMAVSLVIIYQYVVRNMPDPHNLPI 266
L+VFI N F FLA V VS++ IY +++ P + P+
Sbjct: 322 LVVFIGVRYVNKFASLFLACV--IVSILAIYAGAIKSSFAPPHFPV 365
>gi|110224454 solute carrier family 12, member 6 isoform c [Homo
sapiens]
Length = 1091
Score = 32.0 bits (71), Expect = 1.4
Identities = 27/106 (25%), Positives = 47/106 (44%), Gaps = 19/106 (17%)
Query: 164 LGFCSVYIVFLAENVKQVH--EGFLESKVFISNSTNSSNPCERRSVDLRIYMLCFLPFII 221
LG +++V++ H + ES ++N +R+Y FL ++
Sbjct: 226 LGAIEIFLVYIVPRAAIFHSDDALKESAAMLNN--------------MRVYGTAFLVLMV 271
Query: 222 LLVFIR-ELKNLFVLSFLANVSMAVSLVIIYQYVVRNMPDPHNLPI 266
L+VFI N F FLA V VS++ IY +++ P + P+
Sbjct: 272 LVVFIGVRYVNKFASLFLACV--IVSILAIYAGAIKSSFAPPHFPV 315
>gi|110224452 solute carrier family 12, member 6 isoform c [Homo
sapiens]
Length = 1091
Score = 32.0 bits (71), Expect = 1.4
Identities = 27/106 (25%), Positives = 47/106 (44%), Gaps = 19/106 (17%)
Query: 164 LGFCSVYIVFLAENVKQVH--EGFLESKVFISNSTNSSNPCERRSVDLRIYMLCFLPFII 221
LG +++V++ H + ES ++N +R+Y FL ++
Sbjct: 226 LGAIEIFLVYIVPRAAIFHSDDALKESAAMLNN--------------MRVYGTAFLVLMV 271
Query: 222 LLVFIR-ELKNLFVLSFLANVSMAVSLVIIYQYVVRNMPDPHNLPI 266
L+VFI N F FLA V VS++ IY +++ P + P+
Sbjct: 272 LVVFIGVRYVNKFASLFLACV--IVSILAIYAGAIKSSFAPPHFPV 315
>gi|4826780 solute carrier family 12, member 6 isoform b [Homo
sapiens]
Length = 1099
Score = 32.0 bits (71), Expect = 1.4
Identities = 27/106 (25%), Positives = 47/106 (44%), Gaps = 19/106 (17%)
Query: 164 LGFCSVYIVFLAENVKQVH--EGFLESKVFISNSTNSSNPCERRSVDLRIYMLCFLPFII 221
LG +++V++ H + ES ++N +R+Y FL ++
Sbjct: 234 LGAIEIFLVYIVPRAAIFHSDDALKESAAMLNN--------------MRVYGTAFLVLMV 279
Query: 222 LLVFIR-ELKNLFVLSFLANVSMAVSLVIIYQYVVRNMPDPHNLPI 266
L+VFI N F FLA V VS++ IY +++ P + P+
Sbjct: 280 LVVFIGVRYVNKFASLFLACV--IVSILAIYAGAIKSSFAPPHFPV 323
>gi|110224449 solute carrier family 12, member 6 isoform a [Homo
sapiens]
Length = 1150
Score = 32.0 bits (71), Expect = 1.4
Identities = 27/106 (25%), Positives = 47/106 (44%), Gaps = 19/106 (17%)
Query: 164 LGFCSVYIVFLAENVKQVH--EGFLESKVFISNSTNSSNPCERRSVDLRIYMLCFLPFII 221
LG +++V++ H + ES ++N +R+Y FL ++
Sbjct: 285 LGAIEIFLVYIVPRAAIFHSDDALKESAAMLNN--------------MRVYGTAFLVLMV 330
Query: 222 LLVFIR-ELKNLFVLSFLANVSMAVSLVIIYQYVVRNMPDPHNLPI 266
L+VFI N F FLA V VS++ IY +++ P + P+
Sbjct: 331 LVVFIGVRYVNKFASLFLACV--IVSILAIYAGAIKSSFAPPHFPV 374
>gi|225579067 solute carrier family 12, member 4 isoform e [Homo
sapiens]
Length = 1054
Score = 31.6 bits (70), Expect = 1.8
Identities = 20/60 (33%), Positives = 35/60 (58%), Gaps = 3/60 (5%)
Query: 208 DLRIYMLCFLPFIILLVFIR-ELKNLFVLSFLANVSMAVSLVIIYQYVVRNMPDPHNLPI 266
++R+Y FL F+ L+VF+ + N F FLA V +S++ IY ++++ DP P+
Sbjct: 219 NMRVYGTIFLTFMTLVVFVGVKYVNKFASLFLACV--IISILSIYAGGIKSIFDPPVFPV 276
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.326 0.141 0.426
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,620,041
Number of Sequences: 37866
Number of extensions: 741967
Number of successful extensions: 2278
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 19
Number of HSP's that attempted gapping in prelim test: 2237
Number of HSP's gapped (non-prelim): 46
length of query: 504
length of database: 18,247,518
effective HSP length: 107
effective length of query: 397
effective length of database: 14,195,856
effective search space: 5635754832
effective search space used: 5635754832
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.