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Search of human proteins with 40556393
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40556393 PHD finger protein 17 long isoform [Homo sapiens]
(842 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40556393 PHD finger protein 17 long isoform [Homo sapiens] 1729 0.0
gi|19923609 PHD finger protein 17 short isoform [Homo sapiens] 1045 0.0
gi|40556370 PHD finger protein 15 [Homo sapiens] 704 0.0
gi|117190334 PHD finger protein 16 [Homo sapiens] 681 0.0
gi|7662006 PHD finger protein 16 [Homo sapiens] 681 0.0
gi|11321642 bromodomain containing protein 1 [Homo sapiens] 224 3e-58
gi|51173722 bromodomain and PHD finger-containing protein 1 isof... 218 2e-56
gi|51173720 bromodomain and PHD finger-containing protein 1 isof... 218 2e-56
gi|148727368 bromodomain and PHD finger containing, 3 [Homo sapi... 214 2e-55
gi|57222568 myeloid/lymphoid or mixed-lineage leukemia (trithora... 142 2e-33
gi|57546899 myeloid/lymphoid or mixed-lineage leukemia transloca... 134 3e-31
gi|4757726 myeloid/lymphoid or mixed-lineage leukemia translocat... 134 3e-31
gi|55769548 PHD finger protein 14 isoform 2 [Homo sapiens] 132 1e-30
gi|55769550 PHD finger protein 14 isoform 1 [Homo sapiens] 132 1e-30
gi|45504380 jumonji domain containing 2B [Homo sapiens] 105 2e-22
gi|226442889 jumonji domain containing 2C isoform 2 [Homo sapiens] 96 1e-19
gi|109255247 jumonji domain containing 2C isoform 1 [Homo sapiens] 96 1e-19
gi|98986459 jumonji domain containing 2A [Homo sapiens] 95 3e-19
gi|226442893 jumonji domain containing 2C isoform 3 [Homo sapiens] 66 2e-10
gi|226442897 jumonji domain containing 2C isoform 4 [Homo sapiens] 66 2e-10
gi|6678764 metal response element binding transcription factor 2... 50 7e-06
gi|4505777 PHD finger protein 1 isoform a [Homo sapiens] 50 1e-05
gi|13435397 PHD finger protein 1 isoform b [Homo sapiens] 50 1e-05
gi|40807477 retinoic acid induced 1 [Homo sapiens] 48 3e-05
gi|13699811 WHSC1L1 protein isoform long [Homo sapiens] 46 2e-04
gi|194328736 PHD finger protein 10 isoform b [Homo sapiens] 46 2e-04
gi|194328734 PHD finger protein 10 isoform a [Homo sapiens] 46 2e-04
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 45 2e-04
gi|24308089 chromodomain helicase DNA binding protein 5 [Homo sa... 45 2e-04
gi|19913358 Wolf-Hirschhorn syndrome candidate 1 protein isoform... 45 4e-04
>gi|40556393 PHD finger protein 17 long isoform [Homo sapiens]
Length = 842
Score = 1729 bits (4479), Expect = 0.0
Identities = 842/842 (100%), Positives = 842/842 (100%)
Query: 1 MKRGRLPSSSEDSDDNGSLSTTWSQNSRSQHRRSSCSRHEDRKPSEVFRTDLITAMKLHD 60
MKRGRLPSSSEDSDDNGSLSTTWSQNSRSQHRRSSCSRHEDRKPSEVFRTDLITAMKLHD
Sbjct: 1 MKRGRLPSSSEDSDDNGSLSTTWSQNSRSQHRRSSCSRHEDRKPSEVFRTDLITAMKLHD 60
Query: 61 SYQLNPDEYYVLADPWRQEWEKGVQVPVSPGTIPQPVARVVSEEKSLMFIRPKKYIVSSG 120
SYQLNPDEYYVLADPWRQEWEKGVQVPVSPGTIPQPVARVVSEEKSLMFIRPKKYIVSSG
Sbjct: 61 SYQLNPDEYYVLADPWRQEWEKGVQVPVSPGTIPQPVARVVSEEKSLMFIRPKKYIVSSG 120
Query: 121 SEPPELGYVDIRTLADSVCRYDLNDMDAAWLELTNEEFKEMGMPELDEYTMERVLEEFEQ 180
SEPPELGYVDIRTLADSVCRYDLNDMDAAWLELTNEEFKEMGMPELDEYTMERVLEEFEQ
Sbjct: 121 SEPPELGYVDIRTLADSVCRYDLNDMDAAWLELTNEEFKEMGMPELDEYTMERVLEEFEQ 180
Query: 181 RCYDNMNHAIETEEGLGIEYDEDVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYGILKV 240
RCYDNMNHAIETEEGLGIEYDEDVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYGILKV
Sbjct: 181 RCYDNMNHAIETEEGLGIEYDEDVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYGILKV 240
Query: 241 PEGSWLCRTCALGVQPKCLLCPKKGGAMKPTRSGTKWVHVSCALWIPEVSIGSPEKMEPI 300
PEGSWLCRTCALGVQPKCLLCPKKGGAMKPTRSGTKWVHVSCALWIPEVSIGSPEKMEPI
Sbjct: 241 PEGSWLCRTCALGVQPKCLLCPKKGGAMKPTRSGTKWVHVSCALWIPEVSIGSPEKMEPI 300
Query: 301 TKVSHIPSSRWALVCSLCNEKFGASIQCSVKNCRTAFHVTCAFDRGLEMKTILAENDEVK 360
TKVSHIPSSRWALVCSLCNEKFGASIQCSVKNCRTAFHVTCAFDRGLEMKTILAENDEVK
Sbjct: 301 TKVSHIPSSRWALVCSLCNEKFGASIQCSVKNCRTAFHVTCAFDRGLEMKTILAENDEVK 360
Query: 361 FKSYCPKHSSHRKPEESLGKGAAQENGAPECSPRNPLEPFASLEQNREEAHRVSVRKQKL 420
FKSYCPKHSSHRKPEESLGKGAAQENGAPECSPRNPLEPFASLEQNREEAHRVSVRKQKL
Sbjct: 361 FKSYCPKHSSHRKPEESLGKGAAQENGAPECSPRNPLEPFASLEQNREEAHRVSVRKQKL 420
Query: 421 QQLEDEFYTFVNLLDVARALRLPEEVVDFLYQYWKLKRKVNFNKPLITPKKDEEDNLAKR 480
QQLEDEFYTFVNLLDVARALRLPEEVVDFLYQYWKLKRKVNFNKPLITPKKDEEDNLAKR
Sbjct: 421 QQLEDEFYTFVNLLDVARALRLPEEVVDFLYQYWKLKRKVNFNKPLITPKKDEEDNLAKR 480
Query: 481 EQDVLFRRLQLFTHLRQDLERVRNLTYMVTRREKIKRSVCKVQEQIFNLYTKLLEQERVS 540
EQDVLFRRLQLFTHLRQDLERVRNLTYMVTRREKIKRSVCKVQEQIFNLYTKLLEQERVS
Sbjct: 481 EQDVLFRRLQLFTHLRQDLERVRNLTYMVTRREKIKRSVCKVQEQIFNLYTKLLEQERVS 540
Query: 541 GVPSSCSSSSLENMLLFNSPSVGPDAPKIEDLKWHSAFFRKQMGTSLVHSLKKPHKRDPL 600
GVPSSCSSSSLENMLLFNSPSVGPDAPKIEDLKWHSAFFRKQMGTSLVHSLKKPHKRDPL
Sbjct: 541 GVPSSCSSSSLENMLLFNSPSVGPDAPKIEDLKWHSAFFRKQMGTSLVHSLKKPHKRDPL 600
Query: 601 QNSPGSEGKTLLKQPDLCGRREGMVVPESFLGLEKTFAEARLISAQQKNGVVMPDHGKRR 660
QNSPGSEGKTLLKQPDLCGRREGMVVPESFLGLEKTFAEARLISAQQKNGVVMPDHGKRR
Sbjct: 601 QNSPGSEGKTLLKQPDLCGRREGMVVPESFLGLEKTFAEARLISAQQKNGVVMPDHGKRR 660
Query: 661 DNRFHCDLIKGDLKDKSFKQSHKPLRSTDVSQRHLDNTRAATSPGVGQSAPGTRKEIVPK 720
DNRFHCDLIKGDLKDKSFKQSHKPLRSTDVSQRHLDNTRAATSPGVGQSAPGTRKEIVPK
Sbjct: 661 DNRFHCDLIKGDLKDKSFKQSHKPLRSTDVSQRHLDNTRAATSPGVGQSAPGTRKEIVPK 720
Query: 721 CNGSLIKVNYNQTAVKVPTTPASPVKNWGGFRIPKKGERQQQGEAHDGACHQHSDYPYLG 780
CNGSLIKVNYNQTAVKVPTTPASPVKNWGGFRIPKKGERQQQGEAHDGACHQHSDYPYLG
Sbjct: 721 CNGSLIKVNYNQTAVKVPTTPASPVKNWGGFRIPKKGERQQQGEAHDGACHQHSDYPYLG 780
Query: 781 LGRVPAKERAKSKLKSDNENDGYVPDVEMSDSESEASEKKCIHTSSTISRRTDIIRRSIL 840
LGRVPAKERAKSKLKSDNENDGYVPDVEMSDSESEASEKKCIHTSSTISRRTDIIRRSIL
Sbjct: 781 LGRVPAKERAKSKLKSDNENDGYVPDVEMSDSESEASEKKCIHTSSTISRRTDIIRRSIL 840
Query: 841 AS 842
AS
Sbjct: 841 AS 842
>gi|19923609 PHD finger protein 17 short isoform [Homo sapiens]
Length = 509
Score = 1045 bits (2701), Expect = 0.0
Identities = 502/502 (100%), Positives = 502/502 (100%)
Query: 1 MKRGRLPSSSEDSDDNGSLSTTWSQNSRSQHRRSSCSRHEDRKPSEVFRTDLITAMKLHD 60
MKRGRLPSSSEDSDDNGSLSTTWSQNSRSQHRRSSCSRHEDRKPSEVFRTDLITAMKLHD
Sbjct: 1 MKRGRLPSSSEDSDDNGSLSTTWSQNSRSQHRRSSCSRHEDRKPSEVFRTDLITAMKLHD 60
Query: 61 SYQLNPDEYYVLADPWRQEWEKGVQVPVSPGTIPQPVARVVSEEKSLMFIRPKKYIVSSG 120
SYQLNPDEYYVLADPWRQEWEKGVQVPVSPGTIPQPVARVVSEEKSLMFIRPKKYIVSSG
Sbjct: 61 SYQLNPDEYYVLADPWRQEWEKGVQVPVSPGTIPQPVARVVSEEKSLMFIRPKKYIVSSG 120
Query: 121 SEPPELGYVDIRTLADSVCRYDLNDMDAAWLELTNEEFKEMGMPELDEYTMERVLEEFEQ 180
SEPPELGYVDIRTLADSVCRYDLNDMDAAWLELTNEEFKEMGMPELDEYTMERVLEEFEQ
Sbjct: 121 SEPPELGYVDIRTLADSVCRYDLNDMDAAWLELTNEEFKEMGMPELDEYTMERVLEEFEQ 180
Query: 181 RCYDNMNHAIETEEGLGIEYDEDVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYGILKV 240
RCYDNMNHAIETEEGLGIEYDEDVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYGILKV
Sbjct: 181 RCYDNMNHAIETEEGLGIEYDEDVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYGILKV 240
Query: 241 PEGSWLCRTCALGVQPKCLLCPKKGGAMKPTRSGTKWVHVSCALWIPEVSIGSPEKMEPI 300
PEGSWLCRTCALGVQPKCLLCPKKGGAMKPTRSGTKWVHVSCALWIPEVSIGSPEKMEPI
Sbjct: 241 PEGSWLCRTCALGVQPKCLLCPKKGGAMKPTRSGTKWVHVSCALWIPEVSIGSPEKMEPI 300
Query: 301 TKVSHIPSSRWALVCSLCNEKFGASIQCSVKNCRTAFHVTCAFDRGLEMKTILAENDEVK 360
TKVSHIPSSRWALVCSLCNEKFGASIQCSVKNCRTAFHVTCAFDRGLEMKTILAENDEVK
Sbjct: 301 TKVSHIPSSRWALVCSLCNEKFGASIQCSVKNCRTAFHVTCAFDRGLEMKTILAENDEVK 360
Query: 361 FKSYCPKHSSHRKPEESLGKGAAQENGAPECSPRNPLEPFASLEQNREEAHRVSVRKQKL 420
FKSYCPKHSSHRKPEESLGKGAAQENGAPECSPRNPLEPFASLEQNREEAHRVSVRKQKL
Sbjct: 361 FKSYCPKHSSHRKPEESLGKGAAQENGAPECSPRNPLEPFASLEQNREEAHRVSVRKQKL 420
Query: 421 QQLEDEFYTFVNLLDVARALRLPEEVVDFLYQYWKLKRKVNFNKPLITPKKDEEDNLAKR 480
QQLEDEFYTFVNLLDVARALRLPEEVVDFLYQYWKLKRKVNFNKPLITPKKDEEDNLAKR
Sbjct: 421 QQLEDEFYTFVNLLDVARALRLPEEVVDFLYQYWKLKRKVNFNKPLITPKKDEEDNLAKR 480
Query: 481 EQDVLFRRLQLFTHLRQDLERV 502
EQDVLFRRLQLFTHLRQDLERV
Sbjct: 481 EQDVLFRRLQLFTHLRQDLERV 502
>gi|40556370 PHD finger protein 15 [Homo sapiens]
Length = 790
Score = 704 bits (1817), Expect = 0.0
Identities = 423/862 (49%), Positives = 525/862 (60%), Gaps = 96/862 (11%)
Query: 2 KRGRLPSSSEDSDDNGSLSTTWSQNSRSQ---HRRSSCSRHEDRKPSEVFRTDLITAMKL 58
KR + SS++SD S +T+ S + S+ +S R ++KPSEVFRTDLITAMK+
Sbjct: 4 KRRKYSISSDNSDTTDSHATSTSASRCSKLPSSTKSGWPRQNEKKPSEVFRTDLITAMKI 63
Query: 59 HDSYQLNPDEYYVLADPWRQEWEKGVQVPVSPGTIPQPVARVVSE-EKSLMFIRPKKYIV 117
DSYQL+PD+YY+LADPWRQEWEKGVQVP IP+PV R++ E P ++
Sbjct: 64 PDSYQLSPDDYYILADPWRQEWEKGVQVPAGAEAIPEPVVRILPPLEGPPAQASPSSTML 123
Query: 118 SSGSEPPELGYVDIRTLADSVCRYDLNDMDAAWLELTNEEFKEMGMPELDEYTMERVLEE 177
GS+P G RYDL+++DA WLEL N E KEM PELDE T+ERVLEE
Sbjct: 124 GEGSQPDWPGG----------SRYDLDEIDAYWLELINSELKEMERPELDELTLERVLEE 173
Query: 178 FEQRCYDNMNHAIETEEGLGIEYDEDVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYGI 237
E C+ NM AIET+EGLGIEYDEDVVCDVC+SP+GEDGNEMVFCDKCN+CVHQACYGI
Sbjct: 174 LETLCHQNMARAIETQEGLGIEYDEDVVCDVCRSPEGEDGNEMVFCDKCNVCVHQACYGI 233
Query: 238 LKVPEGSWLCRTCALGVQPKCLLCPKKGGAMKPTRSGTKWVHVSCALWIPEVSIGSPEKM 297
LKVP GSWLCRTCALGVQPKCLLCPK+GGA+KPTRSGTKWVHVSCALWIPEVSIG PEKM
Sbjct: 234 LKVPTGSWLCRTCALGVQPKCLLCPKRGGALKPTRSGTKWVHVSCALWIPEVSIGCPEKM 293
Query: 298 EPITKVSHIPSSRWALVCSLCNEKFGASIQCSVKNCRTAFHVTCAFDRGLEMKTILAEND 357
EPITK+SHIP+SRWAL CSLC E G IQCS+ +C TAFHVTCAFD GLEM+TILA+ND
Sbjct: 294 EPITKISHIPASRWALSCSLCKECTGTCIQCSMPSCVTAFHVTCAFDHGLEMRTILADND 353
Query: 358 EVKFKSYCPKHSSHRKPEESLGKGAAQENGAPECSPRN-PLEPFASLEQNREEAHRVSVR 416
EVKFKS+C +HS +G P P + P EP Q E+ +V++R
Sbjct: 354 EVKFKSFCQEHS----------------DGGPRNEPTSEPTEP----SQAGEDLEKVTLR 393
Query: 417 KQKLQQLEDEFYTFVNLLDVARALRLPEEVVDFLYQYWKLKRKVNFNKPLITPKKDEEDN 476
KQ+LQQLE++FY V +VA L L E +VDF+YQYWKLKRK N N+PL+TPK DE DN
Sbjct: 394 KQRLQQLEEDFYELVEPAEVAERLDLAEALVDFIYQYWKLKRKANANQPLLTPKTDEVDN 453
Query: 477 LAKREQDVLFRRLQLFTHLRQDLERVRNLTYMVTRREKIKRSVCKVQEQIFNLYTKLLEQ 536
LA++EQDVL+RRL+LFTHLRQDLERVRNL YMVTRRE+ K ++CK+QEQIF+L KL+EQ
Sbjct: 454 LAQQEQDVLYRRLKLFTHLRQDLERVRNLCYMVTRRERTKHAICKLQEQIFHLQMKLIEQ 513
Query: 537 ERVSGVPSSCSSSSLENMLLFNS---PSVGPDAPKIEDLKWHSAFFRKQMGTSLVHSLKK 593
+ G+ S+S + FNS SV A + +W L
Sbjct: 514 DLCRGL----STSFPIDGTFFNSWLAQSVQITAENMAMSEW---------------PLNN 554
Query: 594 PHKRDPLQNSPGSEGKTLLKQPD--LCGRREGMVVPESFLGLEKTFAEARLISAQQKNGV 651
H+ DP +PG + LL+ + L R+ + P K RL A++K
Sbjct: 555 GHREDP---APGLLSEELLQDEETLLSFMRDPSLRPGD--PARKARGRTRL-PAKKKPPP 608
Query: 652 VMPDHG--------KRRDNRFHCDLIKGDLKDKSFKQSHKPLRSTDVSQRHLDNTRAATS 703
P G K + D G K + KP R T HL ++ AA
Sbjct: 609 PPPQDGPGSRTTPDKAPKKTWGQD--AGSGKGGQGPPTRKPPRRT---SSHLPSSPAAGD 663
Query: 704 PGVGQSAPGTRKEIVPKCNGSLIKVNYNQTAVKVPTTPASPVKNWGGFRIPKKGE--RQQ 761
+ + P + + P+ V + + V+VP ASP K G R P++ + R+
Sbjct: 664 CPI-LATPESPPPLAPETPDEAASVAAD-SDVQVPGPAASP-KPLGRLRPPRESKVTRRL 720
Query: 762 QGEAHDGACHQHSDYPYLGLGRVPA-KERAKSKLKSDNENDGYVPDVEMSDSESEASEKK 820
G D G+G A ER K L D E DGY D EMSDS+ EA E
Sbjct: 721 PGARPDA-----------GMGPPSAVAERPKVSLHFDTETDGYFSDGEMSDSDVEA-EDG 768
Query: 821 CIHTSSTISRRTDIIRRSILAS 842
+ + +++R +LAS
Sbjct: 769 GVQRGPREAGAEEVVRMGVLAS 790
>gi|117190334 PHD finger protein 16 [Homo sapiens]
Length = 823
Score = 681 bits (1756), Expect = 0.0
Identities = 331/563 (58%), Positives = 421/563 (74%), Gaps = 25/563 (4%)
Query: 1 MKRGRLPSSSEDSDDNGSLSTTWSQNSRSQHRRSSCSRHEDRKPSEVFRTDLITAMKLHD 60
MKR R SSS+ SD++ S S T S S +R S +E +KP+EVFR DLI+AMKL D
Sbjct: 1 MKRHRPVSSSDSSDESPSTSFT----SGSMYRIKSKIPNEHKKPAEVFRKDLISAMKLPD 56
Query: 61 SYQLNPDEYYVLADPWRQEWEKGVQVPVSPGTIPQPVARVVSEE-KSLMFIRPKKYIVSS 119
S+ +NPD YY+ AD W++EWEKGVQVP SP T+PQP R+++E+ K ++FIRP+KYI S
Sbjct: 57 SHHINPDSYYLFADTWKEEWEKGVQVPASPDTVPQPSLRIIAEKVKDVLFIRPRKYIHCS 116
Query: 120 GSEPPELGYVDIRTLADSVCRYDLNDMDAAWLELTNEEFKEMGMPELDEYTMERVLEEFE 179
+ E GY++I LA SVCRYDL+DMD WL+ NE+ EMG +DE ME+ +E E
Sbjct: 117 SPDTTEPGYINIMELAASVCRYDLDDMDIFWLQELNEDLAEMGCGPVDENLMEKTVEVLE 176
Query: 180 QRCYDNMNHAIETEEGLGIEYDEDVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYGILK 239
+ C++NMNHAIETEEGLGIEYDEDV+CDVC+SPD E+GN+MVFCDKCN+CVHQACYGILK
Sbjct: 177 RHCHENMNHAIETEEGLGIEYDEDVICDVCRSPDSEEGNDMVFCDKCNVCVHQACYGILK 236
Query: 240 VPEGSWLCRTCALGVQPKCLLCPKKGGAMKPTRSGTKWVHVSCALWIPEVSIGSPEKMEP 299
VPEGSWLCR+C LG+ P+C+LCPKKGGA+K T++GTKW HVSCALWIPEVSI PE+MEP
Sbjct: 237 VPEGSWLCRSCVLGIYPQCVLCPKKGGALKTTKTGTKWAHVSCALWIPEVSIACPERMEP 296
Query: 300 ITKVSHIPSSRWALVCSLCNEKFGASIQCSVKNCRTAFHVTCAFDRGLEMKTILAENDEV 359
ITK+SHIP SRWALVC+LC K GA IQCS+K+C TAFHVTCAF+ GLEMKTIL E DEV
Sbjct: 297 ITKISHIPPSRWALVCNLCKLKTGACIQCSIKSCITAFHVTCAFEHGLEMKTILDEGDEV 356
Query: 360 KFKSYCPKHSSHRKPEESLGKGAAQENGAPECSPRNPLEPFASLEQNREEAHRVSVRKQK 419
KFKSYC KHS +R + LG+ + A EQ++ ++ + S+R QK
Sbjct: 357 KFKSYCLKHSQNR---QKLGEAEYPHHRAK--------------EQSQAKSEKTSLRAQK 399
Query: 420 LQQLEDEFYTFVNLLDVARALRLPEEVVDFLYQYWKLKRKVNFNKPLITPKKDEEDNLAK 479
L++LE+EFY+ V + DVA L +P VDF+Y YWKLKRK NFNKPL PK+DEE+ L +
Sbjct: 400 LRELEEEFYSLVRVEDVAAELGMPTLAVDFIYNYWKLKRKSNFNKPLFPPKEDEENGLVQ 459
Query: 480 REQDVLFRRLQLFTHLRQDLERVRNLTYMVTRREKIKRSVCKVQEQIFNLYTKLLEQERV 539
+++ + R+++F HLRQDLERVRNL YM++RREK+K S K+QEQIF L +LL QE
Sbjct: 460 PKEESIHTRMRMFMHLRQDLERVRNLCYMISRREKLKLSHNKIQEQIFGLQVQLLNQEID 519
Query: 540 SGVPSSCSSSSLENMLLFNSPSV 562
+G+P +++LEN L + P +
Sbjct: 520 AGLP---LTNALENSLFYPPPRI 539
Score = 35.0 bits (79), Expect = 0.29
Identities = 14/22 (63%), Positives = 18/22 (81%)
Query: 799 ENDGYVPDVEMSDSESEASEKK 820
ENDGY PD+E+SDSE+E+ K
Sbjct: 763 ENDGYCPDLELSDSEAESDGNK 784
>gi|7662006 PHD finger protein 16 [Homo sapiens]
Length = 823
Score = 681 bits (1756), Expect = 0.0
Identities = 331/563 (58%), Positives = 421/563 (74%), Gaps = 25/563 (4%)
Query: 1 MKRGRLPSSSEDSDDNGSLSTTWSQNSRSQHRRSSCSRHEDRKPSEVFRTDLITAMKLHD 60
MKR R SSS+ SD++ S S T S S +R S +E +KP+EVFR DLI+AMKL D
Sbjct: 1 MKRHRPVSSSDSSDESPSTSFT----SGSMYRIKSKIPNEHKKPAEVFRKDLISAMKLPD 56
Query: 61 SYQLNPDEYYVLADPWRQEWEKGVQVPVSPGTIPQPVARVVSEE-KSLMFIRPKKYIVSS 119
S+ +NPD YY+ AD W++EWEKGVQVP SP T+PQP R+++E+ K ++FIRP+KYI S
Sbjct: 57 SHHINPDSYYLFADTWKEEWEKGVQVPASPDTVPQPSLRIIAEKVKDVLFIRPRKYIHCS 116
Query: 120 GSEPPELGYVDIRTLADSVCRYDLNDMDAAWLELTNEEFKEMGMPELDEYTMERVLEEFE 179
+ E GY++I LA SVCRYDL+DMD WL+ NE+ EMG +DE ME+ +E E
Sbjct: 117 SPDTTEPGYINIMELAASVCRYDLDDMDIFWLQELNEDLAEMGCGPVDENLMEKTVEVLE 176
Query: 180 QRCYDNMNHAIETEEGLGIEYDEDVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYGILK 239
+ C++NMNHAIETEEGLGIEYDEDV+CDVC+SPD E+GN+MVFCDKCN+CVHQACYGILK
Sbjct: 177 RHCHENMNHAIETEEGLGIEYDEDVICDVCRSPDSEEGNDMVFCDKCNVCVHQACYGILK 236
Query: 240 VPEGSWLCRTCALGVQPKCLLCPKKGGAMKPTRSGTKWVHVSCALWIPEVSIGSPEKMEP 299
VPEGSWLCR+C LG+ P+C+LCPKKGGA+K T++GTKW HVSCALWIPEVSI PE+MEP
Sbjct: 237 VPEGSWLCRSCVLGIYPQCVLCPKKGGALKTTKTGTKWAHVSCALWIPEVSIACPERMEP 296
Query: 300 ITKVSHIPSSRWALVCSLCNEKFGASIQCSVKNCRTAFHVTCAFDRGLEMKTILAENDEV 359
ITK+SHIP SRWALVC+LC K GA IQCS+K+C TAFHVTCAF+ GLEMKTIL E DEV
Sbjct: 297 ITKISHIPPSRWALVCNLCKLKTGACIQCSIKSCITAFHVTCAFEHGLEMKTILDEGDEV 356
Query: 360 KFKSYCPKHSSHRKPEESLGKGAAQENGAPECSPRNPLEPFASLEQNREEAHRVSVRKQK 419
KFKSYC KHS +R + LG+ + A EQ++ ++ + S+R QK
Sbjct: 357 KFKSYCLKHSQNR---QKLGEAEYPHHRAK--------------EQSQAKSEKTSLRAQK 399
Query: 420 LQQLEDEFYTFVNLLDVARALRLPEEVVDFLYQYWKLKRKVNFNKPLITPKKDEEDNLAK 479
L++LE+EFY+ V + DVA L +P VDF+Y YWKLKRK NFNKPL PK+DEE+ L +
Sbjct: 400 LRELEEEFYSLVRVEDVAAELGMPTLAVDFIYNYWKLKRKSNFNKPLFPPKEDEENGLVQ 459
Query: 480 REQDVLFRRLQLFTHLRQDLERVRNLTYMVTRREKIKRSVCKVQEQIFNLYTKLLEQERV 539
+++ + R+++F HLRQDLERVRNL YM++RREK+K S K+QEQIF L +LL QE
Sbjct: 460 PKEESIHTRMRMFMHLRQDLERVRNLCYMISRREKLKLSHNKIQEQIFGLQVQLLNQEID 519
Query: 540 SGVPSSCSSSSLENMLLFNSPSV 562
+G+P +++LEN L + P +
Sbjct: 520 AGLP---LTNALENSLFYPPPRI 539
Score = 35.0 bits (79), Expect = 0.29
Identities = 14/22 (63%), Positives = 18/22 (81%)
Query: 799 ENDGYVPDVEMSDSESEASEKK 820
ENDGY PD+E+SDSE+E+ K
Sbjct: 763 ENDGYCPDLELSDSEAESDGNK 784
>gi|11321642 bromodomain containing protein 1 [Homo sapiens]
Length = 1058
Score = 224 bits (570), Expect = 3e-58
Identities = 149/480 (31%), Positives = 222/480 (46%), Gaps = 65/480 (13%)
Query: 87 PVSPGTIPQPVARVVSEEKSLMFIRPKKYIVSSGSEPPELGYVDIRTLADSVCRYDLNDM 146
P S +P+P R+V RP Y EL D+ YD+++
Sbjct: 111 PASASALPEPKVRIVEYSPPSAPRRPPVYYKFIEKSAEEL---------DNEVEYDMDEE 161
Query: 147 DAAWLELTNEEFKEMGMPELDEYTMERVLEEFEQRCYDNMNHAIETEEGLGIEYDEDVVC 206
D AWLE+ NE+ K +P + + E +++ FE+ + E + + DED VC
Sbjct: 162 DYAWLEIVNEKRKGDCVPAVSQSMFEFLMDRFEKESHCENQKQGEQQSLI----DEDAVC 217
Query: 207 DVCQSPDGEDGNEMVFCDKCNICVHQACYGILKVPEGSWLCRTC--ALGVQPKCLLCPKK 264
+C + ++ N ++FCD CN+ VHQ CYG+ +PEG WLCR C + C+LCP K
Sbjct: 218 CICMDGECQNSNVILFCDMCNLAVHQECYGVPYIPEGQWLCRHCLQSRARPADCVLCPNK 277
Query: 265 GGAMKPTRSGTKWVHVSCALWIPEVSIGSPEKMEPITKVSHIPSSRWALVCSLCNEK-FG 323
GGA K T +W HV CALWIPEV + +EPI V +IP +RW L C LC +K G
Sbjct: 278 GGAFKKT-DDDRWGHVVCALWIPEVGFANTVFIEPIDGVRNIPPARWKLTCYLCKQKGVG 336
Query: 324 ASIQCSVKNCRTAFHVTCAFDRGLEMK-------TILAENDEVKFKSYCPKHS---SHRK 373
A IQC NC TAFHVTCA GL MK T V+ +YC H+ R+
Sbjct: 337 ACIQCHKANCYTAFHVTCAQKAGLYMKMEPVKELTGGGTTFSVRKTAYCDVHTPPGCTRR 396
Query: 374 PEESLGKGAAQENGAPECSPRNPLEPFASLEQNREEAHRVS-----------------VR 416
P G +NG C + ++ S + R++A + +
Sbjct: 397 PLNIYG-DVEMKNGV--CRKESSVKTVRSTSKVRKKAKKAKKALAEPCAVLPTVCAPYIP 453
Query: 417 KQKLQQLEDEFYTFVNLLDVARALRLPEEVVDFLYQYWKLKRKVNFNKPL-------ITP 469
Q+L ++ ++ A++ ++ V+ + YW LKR PL +
Sbjct: 454 PQRLNRIANQV-----------AIQRKKQFVERAHSYWLLKRLSRNGAPLLRRLQSSLQS 502
Query: 470 KKDEEDNLAKREQDVLFRRLQLFTHLRQDLERVRNLTYMVTRREKIKRSVCKVQEQIFNL 529
++ + E +L+ + LR DLER R L ++ +REK+KR KV++ L
Sbjct: 503 QRSSQQRENDEEMKAAKEKLKYWQRLRHDLERARLLIELLRKREKLKREQVKVEQVAMEL 562
>gi|51173722 bromodomain and PHD finger-containing protein 1 isoform
2 [Homo sapiens]
Length = 1214
Score = 218 bits (555), Expect = 2e-56
Identities = 138/429 (32%), Positives = 201/429 (46%), Gaps = 55/429 (12%)
Query: 136 DSVCRYDLNDMDAAWLELTNEEFKEMGMPELDEYTMERVLEEFEQRCYDNMNHAIETEEG 195
D YD+++ D WL++ NE K G+ + + E +++ E+ Y ++ +
Sbjct: 210 DEEVEYDMDEEDYIWLDIMNERRKTEGVSPIPQEIFEYLMDRLEKESYFESHNKGDPNAL 269
Query: 196 LGIEYDEDVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYGILKVPEGSWLCRTCALGVQ 255
+ DED VC +C + ++ N ++FCD CN+ VHQ CYG+ +PEG WLCR C
Sbjct: 270 V----DEDAVCCICNDGECQNSNVILFCDMCNLAVHQECYGVPYIPEGQWLCRRCLQSPS 325
Query: 256 --PKCLLCPKKGGAMKPTRSGTKWVHVSCALWIPEVSIGSPEKMEPITKVSHIPSSRWAL 313
C LCP KGGA K T G +W HV CALWIPEV + +EPI + HIP +RW L
Sbjct: 326 RAVDCALCPNKGGAFKQTDDG-RWAHVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKL 384
Query: 314 VCSLCNEK-FGASIQCSVKNCRTAFHVTCAFDRGLEMKT-------ILAENDEVKFKSYC 365
C +C ++ GA IQC NC TAFHVTCA GL MK + V+ +YC
Sbjct: 385 TCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLYMKMEPVRETGANGTSFSVRKTAYC 444
Query: 366 ----PKHSSHRKPEESLGKGAAQENGAPE----CSPRNPLEPFASLEQNREEAHRVSVRK 417
P S+ R P S +G E+ + S + A ++A ++ K
Sbjct: 445 DIHTPPGSARRLPALSHSEGEEDEDEEEDEGKGWSSEKVKKAKAKSRIKMKKARKILAEK 504
Query: 418 QKLQQL-------EDEFYTFVNLLDVARALRLPEEVVDFLYQYWKLKRKVNFNKPLI--- 467
+ + N L + R + + L+ YW LKR+ PL+
Sbjct: 505 RAAAPVVSVPCIPPHRLSKITNRLTIQR----KSQFMQRLHSYWTLKRQSRNGVPLLRRL 560
Query: 468 ------------TPKKDEEDNLAKREQDVLFRRLQLFTHLRQDLERVRNLTYMVTRREKI 515
+ E+ N A +EQ L+ + LR DLER R L ++ +REK+
Sbjct: 561 QTHLQSQRNCDQVGRDSEDKNWALKEQ------LKSWQRLRHDLERARLLVELIRKREKL 614
Query: 516 KRSVCKVQE 524
KR KVQ+
Sbjct: 615 KRETIKVQQ 623
>gi|51173720 bromodomain and PHD finger-containing protein 1 isoform
1 [Homo sapiens]
Length = 1220
Score = 218 bits (555), Expect = 2e-56
Identities = 138/429 (32%), Positives = 201/429 (46%), Gaps = 55/429 (12%)
Query: 136 DSVCRYDLNDMDAAWLELTNEEFKEMGMPELDEYTMERVLEEFEQRCYDNMNHAIETEEG 195
D YD+++ D WL++ NE K G+ + + E +++ E+ Y ++ +
Sbjct: 210 DEEVEYDMDEEDYIWLDIMNERRKTEGVSPIPQEIFEYLMDRLEKESYFESHNKGDPNAL 269
Query: 196 LGIEYDEDVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYGILKVPEGSWLCRTCALGVQ 255
+ DED VC +C + ++ N ++FCD CN+ VHQ CYG+ +PEG WLCR C
Sbjct: 270 V----DEDAVCCICNDGECQNSNVILFCDMCNLAVHQECYGVPYIPEGQWLCRRCLQSPS 325
Query: 256 --PKCLLCPKKGGAMKPTRSGTKWVHVSCALWIPEVSIGSPEKMEPITKVSHIPSSRWAL 313
C LCP KGGA K T G +W HV CALWIPEV + +EPI + HIP +RW L
Sbjct: 326 RAVDCALCPNKGGAFKQTDDG-RWAHVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKL 384
Query: 314 VCSLCNEK-FGASIQCSVKNCRTAFHVTCAFDRGLEMKT-------ILAENDEVKFKSYC 365
C +C ++ GA IQC NC TAFHVTCA GL MK + V+ +YC
Sbjct: 385 TCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLYMKMEPVRETGANGTSFSVRKTAYC 444
Query: 366 ----PKHSSHRKPEESLGKGAAQENGAPE----CSPRNPLEPFASLEQNREEAHRVSVRK 417
P S+ R P S +G E+ + S + A ++A ++ K
Sbjct: 445 DIHTPPGSARRLPALSHSEGEEDEDEEEDEGKGWSSEKVKKAKAKSRIKMKKARKILAEK 504
Query: 418 QKLQQL-------EDEFYTFVNLLDVARALRLPEEVVDFLYQYWKLKRKVNFNKPLI--- 467
+ + N L + R + + L+ YW LKR+ PL+
Sbjct: 505 RAAAPVVSVPCIPPHRLSKITNRLTIQR----KSQFMQRLHSYWTLKRQSRNGVPLLRRL 560
Query: 468 ------------TPKKDEEDNLAKREQDVLFRRLQLFTHLRQDLERVRNLTYMVTRREKI 515
+ E+ N A +EQ L+ + LR DLER R L ++ +REK+
Sbjct: 561 QTHLQSQRNCDQVGRDSEDKNWALKEQ------LKSWQRLRHDLERARLLVELIRKREKL 614
Query: 516 KRSVCKVQE 524
KR KVQ+
Sbjct: 615 KRETIKVQQ 623
>gi|148727368 bromodomain and PHD finger containing, 3 [Homo
sapiens]
Length = 1205
Score = 214 bits (546), Expect = 2e-55
Identities = 158/511 (30%), Positives = 230/511 (45%), Gaps = 73/511 (14%)
Query: 87 PVSPGTIPQPVARVVSEEK--------SLMFIRPKKYIVSSGSEP--PELGYVDIRTLA- 135
P PG +P ++ +E S +P +V SG +P P L R +
Sbjct: 84 PQFPGKSKKPSSKGKKKESCSKHASGTSFHLPQPSFRMVDSGIQPEAPPLPAAYYRYIEK 143
Query: 136 -----DSVCRYDLNDMDAAWLELTNEEFKEMGMPELDEYTMERVLEEFEQRCYDNMNHAI 190
D+ YD+++ D AWL++ NE+ + G + T E +++ E+ Y + +
Sbjct: 144 PPEDLDAEVEYDMDEEDLAWLDMVNEKRRVDGHSLVSADTFELLVDRLEKESYLE-SRSS 202
Query: 191 ETEEGLGIEYDEDVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYGILKVPEGSWLCRTC 250
++ L DED C VC + + N ++FCD CN+ VHQ CYG+ +PEG WLCR C
Sbjct: 203 GAQQSL---IDEDAFCCVCLDDECHNSNVILFCDICNLAVHQECYGVPYIPEGQWLCRCC 259
Query: 251 ALGVQ--PKCLLCPKKGGAMKPTRSGTKWVHVSCALWIPEVSIGSPEKMEPITKVSHIPS 308
C+LCP KGGA K T G W HV CA+WIPEV + +EPI + +IP
Sbjct: 260 LQSPSRPVDCILCPNKGGAFKQTSDG-HWAHVVCAIWIPEVCFANTVFLEPIEGIDNIPP 318
Query: 309 SRWALVCSLCNEK-FGASIQCSVKNCRTAFHVTCAFDRGLEMK-------TILAENDEVK 360
+RW L C +C +K GA+IQC NC TAFHVTCA GL MK ++ V+
Sbjct: 319 ARWKLTCYICKQKGLGAAIQCHKVNCYTAFHVTCAQRAGLFMKIEPMRETSLNGTIFTVR 378
Query: 361 FKSYCPKHS-----------------SHRKPEESLGKGAAQENGAPECSPRN-------- 395
+YC HS S EE L +G +E E
Sbjct: 379 KTAYCEAHSPPGAATARRKGDSPRSISETGDEEGLKEGDGEEEEEEEVEEEEQEAQGGVS 438
Query: 396 ------PLEPFASLEQ----NREEAHRVSVRKQKLQQLEDEFYTFVNLLDVARALRLPEE 445
P + SL+Q EEA + + + + +N + + + +
Sbjct: 439 GSLKGVPKKSKMSLKQKIKKEPEEAGQDTPSTLPMLAVPQIPSYRLNKICSGLSFQRKNQ 498
Query: 446 VVDFLYQYWKLKRKVNFNKPLIT---PKKDEEDNLAKREQD----VLFRRLQLFTHLRQD 498
+ L+ YW LKR+ PLI + N +REQD + L+ + LR D
Sbjct: 499 FMQRLHNYWLLKRQARNGVPLIRRLHSHLQSQRNAEQREQDEKTSAVKEELKYWQKLRHD 558
Query: 499 LERVRNLTYMVTRREKIKRSVCKVQEQIFNL 529
LER R L ++ +REK+KR KVQ+ L
Sbjct: 559 LERARLLIELIRKREKLKREQVKVQQAAMEL 589
>gi|57222568 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 6 [Homo sapiens]
Length = 1093
Score = 142 bits (357), Expect = 2e-33
Identities = 86/241 (35%), Positives = 116/241 (48%), Gaps = 24/241 (9%)
Query: 206 CDVCQSPDGEDGNEMVFCD--KCNICVHQACYGILKVPEGSWLCRTC---ALGVQPKCLL 260
C VC G N +V+CD C++ VHQACYGI++VP G W CR C + +C L
Sbjct: 8 CCVCSDERGWAENPLVYCDGHACSVAVHQACYGIVQVPTGPWFCRKCESQERAARVRCEL 67
Query: 261 CPKKGGAMKPTRSGTKWVHVSCALWIPEVSIGSPEKMEPITKVSHIPSSRWALVCSLCNE 320
CP K GA+K T +G W HV CAL+IPEV + MEPI + ++P R+ C +C E
Sbjct: 68 CPHKDGALKRTDNG-GWAHVVCALYIPEVQFANVLTMEPIV-LQYVPHDRFNKTCYICEE 125
Query: 321 K-------FGASIQCSVKNCRTAFHVTCAFDRGLEMKTILAENDEVKFKSYCPKHSSHRK 373
+ GA + C+ CR AFHVTCA GL + + E D VK+ YC H S K
Sbjct: 126 QGRESKAASGACMTCNRHGCRQAFHVTCAQMAGLLCEEEVLEVDNVKYCGYCKYHFSKMK 185
Query: 374 PEESL----------GKGAAQENGAPECSPRNPLEPFASLEQNREEAHRVSVRKQKLQQL 423
G G+ G+ S R S +Q + H +K+ +
Sbjct: 186 TSRHSSGGGGGGAGGGGGSMGGGGSGFISGRRSRSASPSTQQEKHPTHHERGQKKSRKDK 245
Query: 424 E 424
E
Sbjct: 246 E 246
>gi|57546899 myeloid/lymphoid or mixed-lineage leukemia translocated
to, 10 isoform b [Homo sapiens]
Length = 1011
Score = 134 bits (338), Expect = 3e-31
Identities = 74/180 (41%), Positives = 97/180 (53%), Gaps = 14/180 (7%)
Query: 206 CDVCQSPDGEDGNEMVFCDK--CNICVHQACYGILKVPEGSWLCRTC---ALGVQPKCLL 260
C VC G N +V+CD C++ VHQACYGI++VP G W CR C + +C L
Sbjct: 25 CCVCSDERGWAENPLVYCDGHGCSVAVHQACYGIVQVPTGPWFCRKCESQERAARVRCEL 84
Query: 261 CPKKGGAMKPTRSGTKWVHVSCALWIPEVSIGSPEKMEPITKVSHIPSSRWALVCSLCNE 320
CP K GA+K T +G W HV CAL+IPEV + MEPI + +P R+ C +C+E
Sbjct: 85 CPHKDGALKRTDNG-GWAHVVCALYIPEVQFANVSTMEPIV-LQSVPHDRYNKTCYICDE 142
Query: 321 K-------FGASIQCSVKNCRTAFHVTCAFDRGLEMKTILAENDEVKFKSYCPKHSSHRK 373
+ GA + C+ CR AFHVTCA GL + D V++ YC H S K
Sbjct: 143 QGRESKAATGACMTCNKHGCRQAFHVTCAQFAGLLCEEEGNGADNVQYCGYCKYHFSKLK 202
>gi|4757726 myeloid/lymphoid or mixed-lineage leukemia translocated
to, 10 isoform a [Homo sapiens]
Length = 1027
Score = 134 bits (338), Expect = 3e-31
Identities = 74/180 (41%), Positives = 97/180 (53%), Gaps = 14/180 (7%)
Query: 206 CDVCQSPDGEDGNEMVFCDK--CNICVHQACYGILKVPEGSWLCRTC---ALGVQPKCLL 260
C VC G N +V+CD C++ VHQACYGI++VP G W CR C + +C L
Sbjct: 25 CCVCSDERGWAENPLVYCDGHGCSVAVHQACYGIVQVPTGPWFCRKCESQERAARVRCEL 84
Query: 261 CPKKGGAMKPTRSGTKWVHVSCALWIPEVSIGSPEKMEPITKVSHIPSSRWALVCSLCNE 320
CP K GA+K T +G W HV CAL+IPEV + MEPI + +P R+ C +C+E
Sbjct: 85 CPHKDGALKRTDNG-GWAHVVCALYIPEVQFANVSTMEPIV-LQSVPHDRYNKTCYICDE 142
Query: 321 K-------FGASIQCSVKNCRTAFHVTCAFDRGLEMKTILAENDEVKFKSYCPKHSSHRK 373
+ GA + C+ CR AFHVTCA GL + D V++ YC H S K
Sbjct: 143 QGRESKAATGACMTCNKHGCRQAFHVTCAQFAGLLCEEEGNGADNVQYCGYCKYHFSKLK 202
>gi|55769548 PHD finger protein 14 isoform 2 [Homo sapiens]
Length = 888
Score = 132 bits (333), Expect = 1e-30
Identities = 100/361 (27%), Positives = 154/361 (42%), Gaps = 62/361 (17%)
Query: 201 DEDVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYGI--------LKVPEGS---WLCRT 249
D ++C VC + ED +E++ CD C I VH+ CYG+ E S W C
Sbjct: 317 DHILICCVCLGDNSEDADEIIQCDNCGITVHEGCYGVDGESDSIMSSASENSTEPWFCDA 376
Query: 250 CALGVQPKCLLCPKKGGAMKPTRSGTKWVHVSCALWIPEVSIGSPEKMEPITKVSHIPSS 309
C GV P C LCP + G K T +G +WVH+ CAL++P V+ G +K+ P+T S
Sbjct: 377 CKCGVSPSCELCPNQDGIFKETDAG-RWVHIVCALYVPGVAFGDIDKLRPVTLTEMNYSK 435
Query: 310 RWALVCSLCNE----KFGASIQCSVKNCRTAFHVTCAFDRGLEMKTILAENDEVKFKSYC 365
A CS C + + G I C CR FHVTCA GL + E+ F +YC
Sbjct: 436 YGAKECSFCEDPRFARTGVCISCDAGMCRAYFHVTCAQKEGLLSEAAAEEDIADPFFAYC 495
Query: 366 PKHSSHRKPE---------ESLGKGAAQENGAPECSPRNPLEPFASLEQNREEAH----- 411
+H+ + +S K + QE + SP A L+Q R +A
Sbjct: 496 KQHADRLDRKWKRKNYLALQSYCKMSLQER-EKQLSPEAQARINARLQQYRAKAELARST 554
Query: 412 ----------------------RVSVRKQKLQQLEDEFYTFVN-----LLDVARALRLPE 444
R +RK +L + + + N +D R + P
Sbjct: 555 RPQAWVPREKLPRPLTSSASAIRKLMRKAELMGISTDIFPVDNSDTSSSVDGRRKHKQPA 614
Query: 445 EVVDFLYQYWKLKRKVNFNKPLITPKKDEEDNLAKREQDVLFRRLQLFTHLRQDLERVRN 504
DF+ Y++ ++ + + +K+ +D L + EQ+ L + L + LE ++N
Sbjct: 615 LTADFVNYYFERNMRMIQIQENMAEQKNIKDKL-ENEQEKLHVE---YNKLCESLEELQN 670
Query: 505 L 505
L
Sbjct: 671 L 671
>gi|55769550 PHD finger protein 14 isoform 1 [Homo sapiens]
Length = 948
Score = 132 bits (333), Expect = 1e-30
Identities = 100/361 (27%), Positives = 154/361 (42%), Gaps = 62/361 (17%)
Query: 201 DEDVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYGI--------LKVPEGS---WLCRT 249
D ++C VC + ED +E++ CD C I VH+ CYG+ E S W C
Sbjct: 317 DHILICCVCLGDNSEDADEIIQCDNCGITVHEGCYGVDGESDSIMSSASENSTEPWFCDA 376
Query: 250 CALGVQPKCLLCPKKGGAMKPTRSGTKWVHVSCALWIPEVSIGSPEKMEPITKVSHIPSS 309
C GV P C LCP + G K T +G +WVH+ CAL++P V+ G +K+ P+T S
Sbjct: 377 CKCGVSPSCELCPNQDGIFKETDAG-RWVHIVCALYVPGVAFGDIDKLRPVTLTEMNYSK 435
Query: 310 RWALVCSLCNE----KFGASIQCSVKNCRTAFHVTCAFDRGLEMKTILAENDEVKFKSYC 365
A CS C + + G I C CR FHVTCA GL + E+ F +YC
Sbjct: 436 YGAKECSFCEDPRFARTGVCISCDAGMCRAYFHVTCAQKEGLLSEAAAEEDIADPFFAYC 495
Query: 366 PKHSSHRKPE---------ESLGKGAAQENGAPECSPRNPLEPFASLEQNREEAH----- 411
+H+ + +S K + QE + SP A L+Q R +A
Sbjct: 496 KQHADRLDRKWKRKNYLALQSYCKMSLQER-EKQLSPEAQARINARLQQYRAKAELARST 554
Query: 412 ----------------------RVSVRKQKLQQLEDEFYTFVN-----LLDVARALRLPE 444
R +RK +L + + + N +D R + P
Sbjct: 555 RPQAWVPREKLPRPLTSSASAIRKLMRKAELMGISTDIFPVDNSDTSSSVDGRRKHKQPA 614
Query: 445 EVVDFLYQYWKLKRKVNFNKPLITPKKDEEDNLAKREQDVLFRRLQLFTHLRQDLERVRN 504
DF+ Y++ ++ + + +K+ +D L + EQ+ L + L + LE ++N
Sbjct: 615 LTADFVNYYFERNMRMIQIQENMAEQKNIKDKL-ENEQEKLHVE---YNKLCESLEELQN 670
Query: 505 L 505
L
Sbjct: 671 L 671
Score = 32.3 bits (72), Expect = 1.9
Identities = 15/50 (30%), Positives = 24/50 (48%), Gaps = 7/50 (14%)
Query: 206 CDVCQSPDGEDGNEMVFCDKCNICVHQACYG--ILKVPEGS---WLCRTC 250
C C+ D +V CD+C +C H C + K P+ + W+C+ C
Sbjct: 871 CATCKGTG--DNENLVRCDECRLCYHFGCLDPPLKKSPKQTGYGWICQEC 918
>gi|45504380 jumonji domain containing 2B [Homo sapiens]
Length = 1096
Score = 105 bits (261), Expect = 2e-22
Identities = 64/167 (38%), Positives = 90/167 (53%), Gaps = 18/167 (10%)
Query: 214 GEDGNE-MVFCDKCNICVHQACYGILK--VPEGSWLCRTCALGV-QPKCLLCPKKGGAMK 269
G+DG ++ C KC + VH +CYGI V EG W C CA +C LC +GGA++
Sbjct: 750 GDDGTSPLIACGKCCLQVHASCYGIRPELVNEG-WTCSRCAAHAWTAECCLCNLRGGALQ 808
Query: 270 PTRSGTKWVHVSCALWIPEVSIGSPEKMEPITKVSHIPSSRWALVCSLCNEKF----GAS 325
T + +W+HV CA+ +PE + + P+ +S IP RW L C C ++ GA
Sbjct: 809 MT-TDRRWIHVICAIAVPEARFLNVIERHPVD-ISAIPEQRWKLKCVYCRKRMKKVSGAC 866
Query: 326 IQCSVKNCRTAFHVTCAFDRGLEMKTILAENDEVKF--KSYCPKHSS 370
IQCS ++C T+FHVTCA G +L E D+ + C KH S
Sbjct: 867 IQCSYEHCSTSFHVTCAHAAG-----VLMEPDDWPYVVSITCLKHKS 908
>gi|226442889 jumonji domain containing 2C isoform 2 [Homo sapiens]
Length = 1047
Score = 95.9 bits (237), Expect = 1e-19
Identities = 58/145 (40%), Positives = 79/145 (54%), Gaps = 13/145 (8%)
Query: 215 EDGNEMVF-CDKCNICVHQACYGIL--KVPEGSWLCRTCALGV-QPKCLLCPKKGGAMKP 270
EDG ++ C KC + VH +CYGI ++ +G WLC C +C LC +GGA+K
Sbjct: 709 EDGTSLLISCAKCCVRVHASCYGIPSHEICDG-WLCARCKRNAWTAECCLCNLRGGALKQ 767
Query: 271 TRSGTKWVHVSCALWIPEVSIGS-PEKMEPITKVSHIPSSRWALVCSLCNEKF----GAS 325
T++ KW HV CA+ +PEV + PE+ + V IP R L C C + GA
Sbjct: 768 TKNN-KWAHVMCAVAVPEVRFTNVPERTQ--IDVGRIPLQRLKLKCIFCRHRVKRVSGAC 824
Query: 326 IQCSVKNCRTAFHVTCAFDRGLEMK 350
IQCS C +FHVTCA G+ M+
Sbjct: 825 IQCSYGRCPASFHVTCAHAAGVLME 849
>gi|109255247 jumonji domain containing 2C isoform 1 [Homo sapiens]
Length = 1056
Score = 95.9 bits (237), Expect = 1e-19
Identities = 58/145 (40%), Positives = 79/145 (54%), Gaps = 13/145 (8%)
Query: 215 EDGNEMVF-CDKCNICVHQACYGIL--KVPEGSWLCRTCALGV-QPKCLLCPKKGGAMKP 270
EDG ++ C KC + VH +CYGI ++ +G WLC C +C LC +GGA+K
Sbjct: 709 EDGTSLLISCAKCCVRVHASCYGIPSHEICDG-WLCARCKRNAWTAECCLCNLRGGALKQ 767
Query: 271 TRSGTKWVHVSCALWIPEVSIGS-PEKMEPITKVSHIPSSRWALVCSLCNEKF----GAS 325
T++ KW HV CA+ +PEV + PE+ + V IP R L C C + GA
Sbjct: 768 TKNN-KWAHVMCAVAVPEVRFTNVPERTQ--IDVGRIPLQRLKLKCIFCRHRVKRVSGAC 824
Query: 326 IQCSVKNCRTAFHVTCAFDRGLEMK 350
IQCS C +FHVTCA G+ M+
Sbjct: 825 IQCSYGRCPASFHVTCAHAAGVLME 849
>gi|98986459 jumonji domain containing 2A [Homo sapiens]
Length = 1064
Score = 94.7 bits (234), Expect = 3e-19
Identities = 63/178 (35%), Positives = 90/178 (50%), Gaps = 17/178 (9%)
Query: 215 EDGNE-MVFCDKCNICVHQACYGI--LKVPEGSWLCRTC-ALGVQPKCLLCPKKGGAMKP 270
EDG +V C KC++ VH +CYG+ K E W+C C A ++ C LC +GGA++
Sbjct: 729 EDGTSILVSCKKCSVRVHASCYGVPPAKASE-DWMCSRCSANALEEDCCLCSLRGGALQR 787
Query: 271 TRSGTKWVHVSCALWIPEVSIGSPEKMEPITKVSHIPSSRWALVCSLCNEK----FGASI 326
+WVHVSCA+ I E + + P+ VS IP R+ L C C ++ G +
Sbjct: 788 ANDD-RWVHVSCAVAILEARFVNIAERSPVD-VSKIPLPRFKLKCIFCKKRRKRTAGCCV 845
Query: 327 QCSVKNCRTAFHVTCAFDRGLEMKTILAENDEVKFKSYCPKHSSHRKPEESLGKGAAQ 384
QCS C TAFHV+CA G ++ + D+ F + H+ P KGA Q
Sbjct: 846 QCSHGRCPTAFHVSCAQAAG-----VMMQPDDWPFVVFITCF-RHKIPNLERAKGALQ 897
>gi|226442893 jumonji domain containing 2C isoform 3 [Homo sapiens]
Length = 813
Score = 65.9 bits (159), Expect = 2e-10
Identities = 41/104 (39%), Positives = 58/104 (55%), Gaps = 9/104 (8%)
Query: 215 EDGNEMVF-CDKCNICVHQACYGI--LKVPEGSWLCRTCALGV-QPKCLLCPKKGGAMKP 270
EDG ++ C KC + VH +CYGI ++ +G WLC C +C LC +GGA+K
Sbjct: 709 EDGTSLLISCAKCCVRVHASCYGIPSHEICDG-WLCARCKRNAWTAECCLCNLRGGALKQ 767
Query: 271 TRSGTKWVHVSCALWIPEVSIGS-PEKMEPITKVSHIPSSRWAL 313
T++ KW HV CA+ +PEV + PE+ + V IP R L
Sbjct: 768 TKN-NKWAHVMCAVAVPEVRFTNVPERTQ--IDVGRIPLQRLKL 808
>gi|226442897 jumonji domain containing 2C isoform 4 [Homo sapiens]
Length = 835
Score = 65.9 bits (159), Expect = 2e-10
Identities = 41/104 (39%), Positives = 58/104 (55%), Gaps = 9/104 (8%)
Query: 215 EDGNEMVF-CDKCNICVHQACYGI--LKVPEGSWLCRTCALGV-QPKCLLCPKKGGAMKP 270
EDG ++ C KC + VH +CYGI ++ +G WLC C +C LC +GGA+K
Sbjct: 731 EDGTSLLISCAKCCVRVHASCYGIPSHEICDG-WLCARCKRNAWTAECCLCNLRGGALKQ 789
Query: 271 TRSGTKWVHVSCALWIPEVSIGS-PEKMEPITKVSHIPSSRWAL 313
T++ KW HV CA+ +PEV + PE+ + V IP R L
Sbjct: 790 TKN-NKWAHVMCAVAVPEVRFTNVPERTQ--IDVGRIPLQRLKL 830
>gi|6678764 metal response element binding transcription factor 2
[Homo sapiens]
Length = 593
Score = 50.4 bits (119), Expect = 7e-06
Identities = 27/73 (36%), Positives = 35/73 (47%), Gaps = 13/73 (17%)
Query: 203 DVVCDVCQSPDGEDGNEMVFCDKCNICVHQACY------GILKVPEGSWLCRTCALGVQP 256
++VC +CQ E NEMV CDKC HQ C+ ++ E WLCR C
Sbjct: 102 EMVCTICQEEYSEAPNEMVICDKCGQGYHQLCHTPHIDSSVIDSDE-KWLCRQCVFAT-- 158
Query: 257 KCLLCPKKGGAMK 269
K+GGA+K
Sbjct: 159 ----TTKRGGALK 167
>gi|4505777 PHD finger protein 1 isoform a [Homo sapiens]
Length = 457
Score = 49.7 bits (117), Expect = 1e-05
Identities = 27/74 (36%), Positives = 40/74 (54%), Gaps = 13/74 (17%)
Query: 202 EDVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYGILKVP---EG---SWLCRTCALGVQ 255
E+++C VC+S GN +V C+KC HQ C+ + + P EG SW+CR C +
Sbjct: 86 EELLCCVCRSETVVPGNRLVSCEKCRHAYHQDCH-VPRAPAPGEGEGTSWVCRQCVFAI- 143
Query: 256 PKCLLCPKKGGAMK 269
K+GGA+K
Sbjct: 144 -----ATKRGGALK 152
>gi|13435397 PHD finger protein 1 isoform b [Homo sapiens]
Length = 567
Score = 49.7 bits (117), Expect = 1e-05
Identities = 27/74 (36%), Positives = 40/74 (54%), Gaps = 13/74 (17%)
Query: 202 EDVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYGILKVP---EG---SWLCRTCALGVQ 255
E+++C VC+S GN +V C+KC HQ C+ + + P EG SW+CR C +
Sbjct: 86 EELLCCVCRSETVVPGNRLVSCEKCRHAYHQDCH-VPRAPAPGEGEGTSWVCRQCVFAI- 143
Query: 256 PKCLLCPKKGGAMK 269
K+GGA+K
Sbjct: 144 -----ATKRGGALK 152
>gi|40807477 retinoic acid induced 1 [Homo sapiens]
Length = 1906
Score = 48.1 bits (113), Expect = 3e-05
Identities = 35/110 (31%), Positives = 49/110 (44%), Gaps = 16/110 (14%)
Query: 261 CPKKGGAMKPTRSGTKWVHVSCALWIPEVSI--GSPEKMEPITKVSHIPSSRWALVCSLC 318
C K+ A + WVH +CA+W V + G ++ KV+ ++CS C
Sbjct: 1807 CSKEAPAEPGGEAQEHWVHEACAVWTGGVYLVAGKLFGLQEAMKVAV------DMMCSSC 1860
Query: 319 NEKFGASIQCSVKNCRTAFHVTCAFDRGLEMKTILAENDEVKFKSYCPKH 368
E GA+I C K C +H CA D G + EN +K CPKH
Sbjct: 1861 QEA-GATIGCCHKGCLHTYHYPCASDAGC---IFIEENFSLK----CPKH 1902
>gi|13699811 WHSC1L1 protein isoform long [Homo sapiens]
Length = 1437
Score = 45.8 bits (107), Expect = 2e-04
Identities = 25/89 (28%), Positives = 41/89 (46%), Gaps = 8/89 (8%)
Query: 202 EDVVCDVCQSPDGEDGNEMVFCD-KCNICVHQACYGILKVPEGSWLCRTCALGVQPKCLL 260
+D VC +C+S G+ ++ C+ +C H C G+ +P+ ++C C G P C
Sbjct: 700 KDTVCQICES----SGDSLIPCEGECCKHFHLECLGLASLPDSKFICMECKTGQHP-CFS 754
Query: 261 CPKKGGAMKPTRSGT--KWVHVSCALWIP 287
C G +K G K+ H +C P
Sbjct: 755 CKVSGKDVKRCSVGACGKFYHEACVRKFP 783
Score = 35.4 bits (80), Expect = 0.22
Identities = 14/39 (35%), Positives = 19/39 (48%), Gaps = 1/39 (2%)
Query: 215 EDGNEMVFCDKCNICVHQACYGILKVPEGSWLCRTCALG 253
E G ++ C+ C H C I ++PEG W C C G
Sbjct: 918 EKGGRLLCCESCPASFHPECLSI-EMPEGCWNCNDCKAG 955
Score = 35.4 bits (80), Expect = 0.22
Identities = 18/54 (33%), Positives = 22/54 (40%), Gaps = 7/54 (12%)
Query: 216 DGNEMVFCDK--CNICVHQACYGILKVPEGSW-----LCRTCALGVQPKCLLCP 262
DG E+V CDK C H C + + P G W C C+ C CP
Sbjct: 1329 DGGELVMCDKKDCPKAYHLLCLNLTQPPYGKWECPWHQCDECSSAAVSFCEFCP 1382
>gi|194328736 PHD finger protein 10 isoform b [Homo sapiens]
Length = 496
Score = 45.8 bits (107), Expect = 2e-04
Identities = 18/45 (40%), Positives = 25/45 (55%), Gaps = 2/45 (4%)
Query: 206 CDVCQSPDGEDGNEMVFCDKCNICVHQACYGILKVPEGSWLCRTC 250
C +C P E+ EM+FCD C+ H C G+ +P G W+C C
Sbjct: 434 CIICGQPHHEE--EMMFCDMCDRGYHTFCVGLGAIPSGRWICDCC 476
>gi|194328734 PHD finger protein 10 isoform a [Homo sapiens]
Length = 498
Score = 45.8 bits (107), Expect = 2e-04
Identities = 18/45 (40%), Positives = 25/45 (55%), Gaps = 2/45 (4%)
Query: 206 CDVCQSPDGEDGNEMVFCDKCNICVHQACYGILKVPEGSWLCRTC 250
C +C P E+ EM+FCD C+ H C G+ +P G W+C C
Sbjct: 436 CIICGQPHHEE--EMMFCDMCDRGYHTFCVGLGAIPSGRWICDCC 478
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 45.4 bits (106), Expect = 2e-04
Identities = 35/120 (29%), Positives = 54/120 (45%), Gaps = 20/120 (16%)
Query: 257 KCLLCPKKGGAMKPTRSG------TKWVHVSCALWIPEVSIGSPEKMEPITKVSHIPSSR 310
+C LC K G A +W HV+CA+W EV E+ + K H +R
Sbjct: 1580 QCALCLKYGDADSKEAGRLLYIGQNEWTHVNCAIWSAEVF----EENDGSLKNVHAAVAR 1635
Query: 311 W-ALVCSLCNEKFGASIQCSVKNCRTAFHVTCAFDRGLEMKTILAENDEVKFKSYCPKHS 369
+ C LC K GA++ C + +C + FH CA + ++D+ K +C KH+
Sbjct: 1636 GRQMRCELC-LKPGATVGCCLSSCLSNFHFMCA-----RASYCIFQDDK---KVFCQKHT 1686
>gi|24308089 chromodomain helicase DNA binding protein 5 [Homo
sapiens]
Length = 1954
Score = 45.4 bits (106), Expect = 2e-04
Identities = 22/60 (36%), Positives = 28/60 (46%), Gaps = 7/60 (11%)
Query: 193 EEGLGIEYDEDVVCDVCQSPDGEDGNEMVFCDKCNICVHQACYG--ILKVPEGSWLCRTC 250
++G G E D C+VCQ G E++ CD C H C + K PEG W C C
Sbjct: 333 DDGDGYETDHQDYCEVCQQ-----GGEIILCDTCPRAYHLVCLDPELEKAPEGKWSCPHC 387
Score = 43.5 bits (101), Expect = 8e-04
Identities = 29/80 (36%), Positives = 37/80 (46%), Gaps = 19/80 (23%)
Query: 191 ETEEGLGIEYDED---VVCDVCQSPDGEDGNEMVFCDKCNICVHQACYG--ILKVPEGSW 245
E EEG G E +ED C VC+ DG E++ CD C H C + ++P G W
Sbjct: 402 EEEEG-GCEEEEDDHMEFCRVCK-----DGGELLCCDACPSSYHLHCLNPPLPEIPNGEW 455
Query: 246 LCRTCALGVQPKCLLCPKKG 265
LC P+C P KG
Sbjct: 456 LC--------PRCTCPPLKG 467
>gi|19913358 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
[Homo sapiens]
Length = 1365
Score = 44.7 bits (104), Expect = 4e-04
Identities = 27/95 (28%), Positives = 45/95 (47%), Gaps = 11/95 (11%)
Query: 197 GIEYDEDVVCDVCQSPDGEDGNEMVFCD-KCNICVHQACYGILKVPEGSWLCRTCALGVQ 255
G+ ++ VC +C+ P ++ C+ C H AC G+ + PEG + C CA G+
Sbjct: 661 GVTAKKEYVCQLCEKP-----GSLLLCEGPCCGAFHLACLGLSRRPEGRFTCSECASGIH 715
Query: 256 PKCLLCPKKGGAMK---PTRSGTKWVHVSCALWIP 287
C +C + +K T+ G K+ H +C P
Sbjct: 716 -SCFVCKESKTDVKRCVVTQCG-KFYHEACVKKYP 748
Score = 37.0 bits (84), Expect = 0.077
Identities = 16/48 (33%), Positives = 22/48 (45%), Gaps = 6/48 (12%)
Query: 206 CDVCQSPDGEDGNEMVFCDKCNICVHQACYGILKVPEGSWLCRTCALG 253
C VC G ++ C+ C H C I ++P+GSW C C G
Sbjct: 834 CFVCSK-----GGSLLCCESCPAAFHPDCLNI-EMPDGSWFCNDCRAG 875
Score = 37.0 bits (84), Expect = 0.077
Identities = 20/54 (37%), Positives = 27/54 (50%), Gaps = 7/54 (12%)
Query: 216 DGNEMVFCDK--CNICVHQACYGILKVPEGSWLC--RTCALGVQPK---CLLCP 262
DG ++V CD+ C H +C G+ K P G W C C + +P C LCP
Sbjct: 1247 DGGQLVLCDRKFCTKAYHLSCLGLGKRPFGKWECPWHHCDVCGKPSTSFCHLCP 1300
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.132 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,570,373
Number of Sequences: 37866
Number of extensions: 1846361
Number of successful extensions: 6213
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 41
Number of HSP's successfully gapped in prelim test: 121
Number of HSP's that attempted gapping in prelim test: 5900
Number of HSP's gapped (non-prelim): 321
length of query: 842
length of database: 18,247,518
effective HSP length: 111
effective length of query: 731
effective length of database: 14,044,392
effective search space: 10266450552
effective search space used: 10266450552
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.