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Search of human proteins with 40548384
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40548384 multidrug resistance-related protein [Homo sapiens]
(117 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40548384 multidrug resistance-related protein [Homo sapiens] 252 5e-68
gi|40548382 multidrug resistance-related protein [Homo sapiens] 252 5e-68
gi|226442736 ring finger protein 222 [Homo sapiens] 33 0.048
gi|239756718 PREDICTED: ring finger protein 222 [Homo sapiens] 33 0.048
gi|239751213 PREDICTED: ring finger protein 222 [Homo sapiens] 33 0.048
gi|239745703 PREDICTED: ring finger protein 222 [Homo sapiens] 33 0.048
gi|157412249 RUN and SH3 domain containing 1 isoform c [Homo sap... 30 0.53
gi|157412245 RUN and SH3 domain containing 1 isoform a [Homo sap... 30 0.53
gi|42476123 RUN and SH3 domain containing 1 isoform d [Homo sapi... 30 0.53
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] 30 0.53
gi|169163761 PREDICTED: hypothetical protein isoform 1 [Homo sap... 29 0.70
gi|106879204 exocyst complex component 3-like [Homo sapiens] 29 0.70
gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens] 29 0.91
gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens] 29 0.91
gi|4885065 amyloid precursor-like protein 1 isoform 2 precursor ... 29 0.91
gi|67782338 amyloid precursor-like protein 1 isoform 1 precursor... 29 0.91
gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] 29 0.91
gi|122937293 tubulin tyrosine ligase-like family, member 8 [Homo... 29 0.91
gi|222352129 von Willebrand factor A domain containing 5B2 [Homo... 28 1.2
gi|165932370 FAT tumor suppressor homolog 4 [Homo sapiens] 28 1.2
gi|15529976 zinc finger protein 764 [Homo sapiens] 28 1.2
gi|149944516 tet oncogene family member 3 [Homo sapiens] 28 2.0
gi|239757605 PREDICTED: hypothetical protein [Homo sapiens] 27 2.6
gi|239755810 PREDICTED: hypothetical protein [Homo sapiens] 27 2.6
gi|239752107 PREDICTED: hypothetical protein [Homo sapiens] 27 2.6
gi|239750310 PREDICTED: hypothetical protein [Homo sapiens] 27 2.6
gi|239749721 PREDICTED: hypothetical protein [Homo sapiens] 27 2.6
gi|239746611 PREDICTED: hypothetical protein XP_002343792 [Homo ... 27 2.6
gi|239744621 PREDICTED: hypothetical protein [Homo sapiens] 27 2.6
gi|239743976 PREDICTED: hypothetical protein [Homo sapiens] 27 2.6
>gi|40548384 multidrug resistance-related protein [Homo sapiens]
Length = 117
Score = 252 bits (643), Expect = 5e-68
Identities = 117/117 (100%), Positives = 117/117 (100%)
Query: 1 MTVLEAVLEIQAITGSRLLSMVPGPARPPGSCWDPTQCTRTWLLSHTPRRRWISGLPRAS 60
MTVLEAVLEIQAITGSRLLSMVPGPARPPGSCWDPTQCTRTWLLSHTPRRRWISGLPRAS
Sbjct: 1 MTVLEAVLEIQAITGSRLLSMVPGPARPPGSCWDPTQCTRTWLLSHTPRRRWISGLPRAS 60
Query: 61 CRLGEEPPPLPYCDQAYGEELSIRHRETWAWLSRTDTAWPGAPGVKQARILGELLLV 117
CRLGEEPPPLPYCDQAYGEELSIRHRETWAWLSRTDTAWPGAPGVKQARILGELLLV
Sbjct: 61 CRLGEEPPPLPYCDQAYGEELSIRHRETWAWLSRTDTAWPGAPGVKQARILGELLLV 117
>gi|40548382 multidrug resistance-related protein [Homo sapiens]
Length = 117
Score = 252 bits (643), Expect = 5e-68
Identities = 117/117 (100%), Positives = 117/117 (100%)
Query: 1 MTVLEAVLEIQAITGSRLLSMVPGPARPPGSCWDPTQCTRTWLLSHTPRRRWISGLPRAS 60
MTVLEAVLEIQAITGSRLLSMVPGPARPPGSCWDPTQCTRTWLLSHTPRRRWISGLPRAS
Sbjct: 1 MTVLEAVLEIQAITGSRLLSMVPGPARPPGSCWDPTQCTRTWLLSHTPRRRWISGLPRAS 60
Query: 61 CRLGEEPPPLPYCDQAYGEELSIRHRETWAWLSRTDTAWPGAPGVKQARILGELLLV 117
CRLGEEPPPLPYCDQAYGEELSIRHRETWAWLSRTDTAWPGAPGVKQARILGELLLV
Sbjct: 61 CRLGEEPPPLPYCDQAYGEELSIRHRETWAWLSRTDTAWPGAPGVKQARILGELLLV 117
>gi|226442736 ring finger protein 222 [Homo sapiens]
Length = 220
Score = 33.1 bits (74), Expect = 0.048
Identities = 26/73 (35%), Positives = 31/73 (42%), Gaps = 1/73 (1%)
Query: 23 PGPARPPGSCWDPTQCTRTWLLSHTPRRRWISGLPRASCRLGEEPPPLPYCDQAYGEELS 82
PG ARPPGS Q LL PR I + R LGE+ LP A E S
Sbjct: 120 PGQARPPGSPGQSAQLPLD-LLPSLPRESQIFVISRHGMPLGEQDSVLPRRSLAELSEAS 178
Query: 83 IRHRETWAWLSRT 95
+ R A+ R+
Sbjct: 179 LAPRSARAFCCRS 191
>gi|239756718 PREDICTED: ring finger protein 222 [Homo sapiens]
Length = 220
Score = 33.1 bits (74), Expect = 0.048
Identities = 26/73 (35%), Positives = 31/73 (42%), Gaps = 1/73 (1%)
Query: 23 PGPARPPGSCWDPTQCTRTWLLSHTPRRRWISGLPRASCRLGEEPPPLPYCDQAYGEELS 82
PG ARPPGS Q LL PR I + R LGE+ LP A E S
Sbjct: 120 PGQARPPGSPGQSAQLPLD-LLPSLPRESQIFVISRHGMPLGEQDSVLPRRSLAELSEAS 178
Query: 83 IRHRETWAWLSRT 95
+ R A+ R+
Sbjct: 179 LAPRSARAFCCRS 191
>gi|239751213 PREDICTED: ring finger protein 222 [Homo sapiens]
Length = 220
Score = 33.1 bits (74), Expect = 0.048
Identities = 26/73 (35%), Positives = 31/73 (42%), Gaps = 1/73 (1%)
Query: 23 PGPARPPGSCWDPTQCTRTWLLSHTPRRRWISGLPRASCRLGEEPPPLPYCDQAYGEELS 82
PG ARPPGS Q LL PR I + R LGE+ LP A E S
Sbjct: 120 PGQARPPGSPGQSAQLPLD-LLPSLPRESQIFVISRHGMPLGEQDSVLPRRSLAELSEAS 178
Query: 83 IRHRETWAWLSRT 95
+ R A+ R+
Sbjct: 179 LAPRSARAFCCRS 191
>gi|239745703 PREDICTED: ring finger protein 222 [Homo sapiens]
Length = 220
Score = 33.1 bits (74), Expect = 0.048
Identities = 26/73 (35%), Positives = 31/73 (42%), Gaps = 1/73 (1%)
Query: 23 PGPARPPGSCWDPTQCTRTWLLSHTPRRRWISGLPRASCRLGEEPPPLPYCDQAYGEELS 82
PG ARPPGS Q LL PR I + R LGE+ LP A E S
Sbjct: 120 PGQARPPGSPGQSAQLPLD-LLPSLPRESQIFVISRHGMPLGEQDSVLPRRSLAELSEAS 178
Query: 83 IRHRETWAWLSRT 95
+ R A+ R+
Sbjct: 179 LAPRSARAFCCRS 191
>gi|157412249 RUN and SH3 domain containing 1 isoform c [Homo
sapiens]
Length = 492
Score = 29.6 bits (65), Expect = 0.53
Identities = 25/79 (31%), Positives = 31/79 (39%), Gaps = 14/79 (17%)
Query: 29 PGSCWDP-TQCTRTWLLSHT---PRRRWISGLPRASCRLGEEPPPLPYCDQAYGEELSIR 84
PGS W+ TQ +R + T P RW G + G + PLP + A G L
Sbjct: 316 PGSWWEQLTQASRVYASGGTEGFPLSRWAPGRHGTAAEEGAQERPLPTDEMAPGRGL--- 372
Query: 85 HRETWAWLSRTDTAWPGAP 103
WL R PG P
Sbjct: 373 ------WLGRL-FGVPGGP 384
>gi|157412245 RUN and SH3 domain containing 1 isoform a [Homo
sapiens]
Length = 902
Score = 29.6 bits (65), Expect = 0.53
Identities = 25/79 (31%), Positives = 31/79 (39%), Gaps = 14/79 (17%)
Query: 29 PGSCWDP-TQCTRTWLLSHT---PRRRWISGLPRASCRLGEEPPPLPYCDQAYGEELSIR 84
PGS W+ TQ +R + T P RW G + G + PLP + A G L
Sbjct: 726 PGSWWEQLTQASRVYASGGTEGFPLSRWAPGRHGTAAEEGAQERPLPTDEMAPGRGL--- 782
Query: 85 HRETWAWLSRTDTAWPGAP 103
WL R PG P
Sbjct: 783 ------WLGRL-FGVPGGP 794
>gi|42476123 RUN and SH3 domain containing 1 isoform d [Homo
sapiens]
Length = 433
Score = 29.6 bits (65), Expect = 0.53
Identities = 25/79 (31%), Positives = 31/79 (39%), Gaps = 14/79 (17%)
Query: 29 PGSCWDP-TQCTRTWLLSHT---PRRRWISGLPRASCRLGEEPPPLPYCDQAYGEELSIR 84
PGS W+ TQ +R + T P RW G + G + PLP + A G L
Sbjct: 257 PGSWWEQLTQASRVYASGGTEGFPLSRWAPGRHGTAAEEGAQERPLPTDEMAPGRGL--- 313
Query: 85 HRETWAWLSRTDTAWPGAP 103
WL R PG P
Sbjct: 314 ------WLGRL-FGVPGGP 325
>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
Length = 1682
Score = 29.6 bits (65), Expect = 0.53
Identities = 25/83 (30%), Positives = 31/83 (37%), Gaps = 29/83 (34%)
Query: 19 LSMVPGPARPPGSCWDPTQCTRTWLLSHTPRRRWISGLPRASCRLGEE------------ 66
LS+ PGP+ PP P C R LL P W+ G +CR E
Sbjct: 459 LSLPPGPSSPP-----PPPCPR--LLRPPPPPAWLKG---PACRAAREDGEILEELFFGT 508
Query: 67 -------PPPLPYCDQAYGEELS 82
PPPLP+ + G S
Sbjct: 509 EGPPRPAPPPLPHREGFLGPPAS 531
>gi|169163761 PREDICTED: hypothetical protein isoform 1 [Homo
sapiens]
Length = 166
Score = 29.3 bits (64), Expect = 0.70
Identities = 13/25 (52%), Positives = 16/25 (64%)
Query: 47 TPRRRWISGLPRASCRLGEEPPPLP 71
+P RR I L RA+ RL + PPP P
Sbjct: 105 SPNRRCIRDLSRAALRLPQPPPPQP 129
>gi|106879204 exocyst complex component 3-like [Homo sapiens]
Length = 746
Score = 29.3 bits (64), Expect = 0.70
Identities = 13/28 (46%), Positives = 15/28 (53%)
Query: 18 LLSMVPGPARPPGSCWDPTQCTRTWLLS 45
L S+VP PA P SC C R LL+
Sbjct: 718 LFSLVPAPALAPASCLPSGSCARALLLA 745
>gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]
Length = 1669
Score = 28.9 bits (63), Expect = 0.91
Identities = 25/83 (30%), Positives = 31/83 (37%), Gaps = 18/83 (21%)
Query: 23 PGPARPPGSCWDPTQCTRTWLLSHTPRRRWISGLPRASCRLGEEPPPLPYCDQAYGEELS 82
PGP PG P T P+ + GLP +G PP LP D G+
Sbjct: 1215 PGPQGQPGLPGSPGHATEGPKGDRGPQGQ--PGLPGLPGPMG--PPGLPGIDGVKGD--- 1267
Query: 83 IRHRETWAWLSRTDTAWPGAPGV 105
+ + WPGAPGV
Sbjct: 1268 -----------KGNPGWPGAPGV 1279
>gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]
Length = 1073
Score = 28.9 bits (63), Expect = 0.91
Identities = 11/17 (64%), Positives = 13/17 (76%), Gaps = 1/17 (5%)
Query: 22 VPGPARPPGSCWDPTQC 38
+PGP PPG C DP+QC
Sbjct: 1042 LPGPPGPPGQC-DPSQC 1057
>gi|4885065 amyloid precursor-like protein 1 isoform 2 precursor
[Homo sapiens]
Length = 650
Score = 28.9 bits (63), Expect = 0.91
Identities = 25/79 (31%), Positives = 30/79 (37%), Gaps = 1/79 (1%)
Query: 1 MTVLEAVLEIQAITGSRLLSMVPGPARPPGSCWDPTQCTRTWLLSHTPRRRWISGLPRAS 60
+ +L +L Q GS L PG A PGS C R L RW R+
Sbjct: 24 LPLLLLLLRAQPAIGS-LAGGSPGAAEAPGSAQVAGLCGRLTLHRDLRTGRWEPDPQRSR 82
Query: 61 CRLGEEPPPLPYCDQAYGE 79
L + L YC Q Y E
Sbjct: 83 RCLRDPQRVLEYCRQMYPE 101
>gi|67782338 amyloid precursor-like protein 1 isoform 1 precursor
[Homo sapiens]
Length = 651
Score = 28.9 bits (63), Expect = 0.91
Identities = 25/79 (31%), Positives = 30/79 (37%), Gaps = 1/79 (1%)
Query: 1 MTVLEAVLEIQAITGSRLLSMVPGPARPPGSCWDPTQCTRTWLLSHTPRRRWISGLPRAS 60
+ +L +L Q GS L PG A PGS C R L RW R+
Sbjct: 24 LPLLLLLLRAQPAIGS-LAGGSPGAAEAPGSAQVAGLCGRLTLHRDLRTGRWEPDPQRSR 82
Query: 61 CRLGEEPPPLPYCDQAYGE 79
L + L YC Q Y E
Sbjct: 83 RCLRDPQRVLEYCRQMYPE 101
>gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]
Length = 1626
Score = 28.9 bits (63), Expect = 0.91
Identities = 11/17 (64%), Positives = 13/17 (76%), Gaps = 1/17 (5%)
Query: 22 VPGPARPPGSCWDPTQC 38
+PGP PPG C DP+QC
Sbjct: 1595 LPGPPGPPGQC-DPSQC 1610
>gi|122937293 tubulin tyrosine ligase-like family, member 8 [Homo
sapiens]
Length = 834
Score = 28.9 bits (63), Expect = 0.91
Identities = 25/81 (30%), Positives = 28/81 (34%), Gaps = 9/81 (11%)
Query: 25 PARPPGSCWDPTQCTRTWLLSHTPRRRWISGLPRASCRLGEEPPPLPYCDQAYGEELSIR 84
P P WDP Q L+ P + GL A L PPP + L
Sbjct: 695 PVAQPAKSWDPNQ------LNAHPLEPVLRGLKTAEGAL--RPPPGGKGEGTVCSRLP-H 745
Query: 85 HRETWAWLSRTDTAWPGAPGV 105
H A T T W G PGV
Sbjct: 746 HGHHVAACQTTGTTWDGGPGV 766
>gi|222352129 von Willebrand factor A domain containing 5B2 [Homo
sapiens]
Length = 1242
Score = 28.5 bits (62), Expect = 1.2
Identities = 12/17 (70%), Positives = 12/17 (70%), Gaps = 1/17 (5%)
Query: 23 PGPARPPGSCWD-PTQC 38
PGP RPPG C D PT C
Sbjct: 165 PGPPRPPGLCDDSPTSC 181
>gi|165932370 FAT tumor suppressor homolog 4 [Homo sapiens]
Length = 4981
Score = 28.5 bits (62), Expect = 1.2
Identities = 20/53 (37%), Positives = 25/53 (47%), Gaps = 8/53 (15%)
Query: 25 PARPPGSCWDP------TQCTRT-WLLSHTPRRRWISGL-PRASCRLGEEPPP 69
P R G W P +Q R WLLS P + W+ G PR ++ EE PP
Sbjct: 5 PDRATGRPWLPLHTLSVSQLLRVFWLLSLLPGQAWVHGAEPRQVFQVLEEQPP 57
>gi|15529976 zinc finger protein 764 [Homo sapiens]
Length = 408
Score = 28.5 bits (62), Expect = 1.2
Identities = 16/51 (31%), Positives = 27/51 (52%), Gaps = 9/51 (17%)
Query: 64 GEEPPPLPYCDQAYGEELSIRHRETWAWLSRTDTAWPGAPGVKQARILGEL 114
GE+P P P C + +G++ ++ + W+ R PGA G + R+ G L
Sbjct: 339 GEKPYPCPQCGRRFGQKSAVAKHQ---WVHR-----PGAGG-HRGRVAGRL 380
>gi|149944516 tet oncogene family member 3 [Homo sapiens]
Length = 1660
Score = 27.7 bits (60), Expect = 2.0
Identities = 19/60 (31%), Positives = 25/60 (41%), Gaps = 1/60 (1%)
Query: 4 LEAVLEIQAITGSRLLSMVPGPARPPGSCWDPTQCTRTWLLSHTPRRRWISGLPRASCRL 63
LE ++ + G +PGP PPG P TR L S P+ GLP + L
Sbjct: 151 LEGKIKSVVMEGGEERPRLPGPL-PPGEAGLPAPSTRPLLSSEVPQISPQEGLPLSQSAL 209
>gi|239757605 PREDICTED: hypothetical protein [Homo sapiens]
Length = 115
Score = 27.3 bits (59), Expect = 2.6
Identities = 16/36 (44%), Positives = 17/36 (47%), Gaps = 5/36 (13%)
Query: 39 TRTWLLSHTPRRRW-----ISGLPRASCRLGEEPPP 69
T W L+ TPRRRW SG PR S P P
Sbjct: 2 TNPWALALTPRRRWWPRARPSGQPRPSRGSSLVPAP 37
>gi|239755810 PREDICTED: hypothetical protein [Homo sapiens]
Length = 499
Score = 27.3 bits (59), Expect = 2.6
Identities = 19/46 (41%), Positives = 20/46 (43%), Gaps = 8/46 (17%)
Query: 24 GPARPP-GSCWDPTQCTRTWLLSHTPRRRWISGLPRASCRLGEEPP 68
GP P GS WDP T L H R PRA C L +PP
Sbjct: 340 GPRAPDAGSFWDPNPQT---LAPHPQASR----RPRAGCSLSLQPP 378
>gi|239752107 PREDICTED: hypothetical protein [Homo sapiens]
Length = 115
Score = 27.3 bits (59), Expect = 2.6
Identities = 16/36 (44%), Positives = 17/36 (47%), Gaps = 5/36 (13%)
Query: 39 TRTWLLSHTPRRRW-----ISGLPRASCRLGEEPPP 69
T W L+ TPRRRW SG PR S P P
Sbjct: 2 TNPWALALTPRRRWWPRARPSGQPRPSRGSSLVPAP 37
>gi|239750310 PREDICTED: hypothetical protein [Homo sapiens]
Length = 499
Score = 27.3 bits (59), Expect = 2.6
Identities = 19/46 (41%), Positives = 20/46 (43%), Gaps = 8/46 (17%)
Query: 24 GPARPP-GSCWDPTQCTRTWLLSHTPRRRWISGLPRASCRLGEEPP 68
GP P GS WDP T L H R PRA C L +PP
Sbjct: 340 GPRAPDAGSFWDPNPQT---LAPHPQASR----RPRAGCSLSLQPP 378
>gi|239749721 PREDICTED: hypothetical protein [Homo sapiens]
Length = 378
Score = 27.3 bits (59), Expect = 2.6
Identities = 20/54 (37%), Positives = 23/54 (42%), Gaps = 8/54 (14%)
Query: 23 PGPARPPGSCWDPTQCTRTWLLSHTPRRRWISGLPRASCRLGEEPPPLPYCDQA 76
PG ARPP S D + + LS PRR G LG P P+P A
Sbjct: 23 PGKARPPSSSGDQRRHPQ---LSRPPRRDLTGG-----SDLGPPPRPVPQLPDA 68
>gi|239746611 PREDICTED: hypothetical protein XP_002343792 [Homo
sapiens]
Length = 115
Score = 27.3 bits (59), Expect = 2.6
Identities = 16/36 (44%), Positives = 17/36 (47%), Gaps = 5/36 (13%)
Query: 39 TRTWLLSHTPRRRW-----ISGLPRASCRLGEEPPP 69
T W L+ TPRRRW SG PR S P P
Sbjct: 2 TNPWALALTPRRRWWPRARPSGQPRPSRGSSLVPAP 37
>gi|239744621 PREDICTED: hypothetical protein [Homo sapiens]
Length = 536
Score = 27.3 bits (59), Expect = 2.6
Identities = 19/46 (41%), Positives = 20/46 (43%), Gaps = 8/46 (17%)
Query: 24 GPARPP-GSCWDPTQCTRTWLLSHTPRRRWISGLPRASCRLGEEPP 68
GP P GS WDP T L H R PRA C L +PP
Sbjct: 377 GPRAPDAGSFWDPNPQT---LAPHPQASR----RPRAGCSLSLQPP 415
>gi|239743976 PREDICTED: hypothetical protein [Homo sapiens]
Length = 378
Score = 27.3 bits (59), Expect = 2.6
Identities = 20/54 (37%), Positives = 23/54 (42%), Gaps = 8/54 (14%)
Query: 23 PGPARPPGSCWDPTQCTRTWLLSHTPRRRWISGLPRASCRLGEEPPPLPYCDQA 76
PG ARPP S D + + LS PRR G LG P P+P A
Sbjct: 23 PGKARPPSSSGDQRRHPQ---LSRPPRRDLTGG-----SDLGPPPRPVPQLPDA 68
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.137 0.467
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,416,784
Number of Sequences: 37866
Number of extensions: 351432
Number of successful extensions: 1059
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 39
Number of HSP's that attempted gapping in prelim test: 1031
Number of HSP's gapped (non-prelim): 64
length of query: 117
length of database: 18,247,518
effective HSP length: 87
effective length of query: 30
effective length of database: 14,953,176
effective search space: 448595280
effective search space used: 448595280
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 55 (25.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.