Guide to the Human Genome
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Search of human proteins with 40254947

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|40254947 thioredoxin-related transmembrane protein 4 [Homo
sapiens]
         (349 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|40254947 thioredoxin-related transmembrane protein 4 [Homo sa...   715   0.0  
gi|151101292 thioredoxin domain containing 1 [Homo sapiens]           222   4e-58
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)...    57   3e-08
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)...    57   3e-08
gi|150378493 MYST histone acetyltransferase (monocytic leukemia)...    57   3e-08
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom...    55   9e-08
gi|17975763 myelin transcription factor 1 [Homo sapiens]               54   3e-07
gi|239756368 PREDICTED: similar to acidic (leucine-rich) nuclear...    53   4e-07
gi|239750893 PREDICTED: similar to acidic (leucine-rich) nuclear...    53   4e-07
gi|42794771 thioredoxin domain containing 5 isoform 1 precursor ...    53   4e-07
gi|224493972 thioredoxin domain containing 5 isoform 3 [Homo sap...    53   4e-07
gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 famil...    53   4e-07
gi|221219020 NYD-SP11 protein [Homo sapiens]                           52   6e-07
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]     52   6e-07
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]     52   6e-07
gi|105990539 neurofilament, light polypeptide 68kDa [Homo sapiens]     52   6e-07
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof...    52   6e-07
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof...    52   6e-07
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof...    52   6e-07
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof...    52   6e-07
gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isof...    52   6e-07
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof...    52   6e-07
gi|55956788 nucleolin [Homo sapiens]                                   52   8e-07
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    52   8e-07
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]           52   8e-07
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]           52   8e-07
gi|21361639 DIPB protein [Homo sapiens]                                51   1e-06
gi|42476169 Paf1, RNA polymerase II associated factor, homolog [...    51   1e-06
gi|75677335 digestive-organ expansion factor homolog [Homo sapiens]    51   1e-06
gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 fami...    51   2e-06

>gi|40254947 thioredoxin-related transmembrane protein 4 [Homo
           sapiens]
          Length = 349

 Score =  715 bits (1846), Expect = 0.0
 Identities = 349/349 (100%), Positives = 349/349 (100%)

Query: 1   MAGGRCGPQLTALLAAWIAAVAATAGPEEAALPPEQSRVQPMTASNWTLVMEGEWMLKFY 60
           MAGGRCGPQLTALLAAWIAAVAATAGPEEAALPPEQSRVQPMTASNWTLVMEGEWMLKFY
Sbjct: 1   MAGGRCGPQLTALLAAWIAAVAATAGPEEAALPPEQSRVQPMTASNWTLVMEGEWMLKFY 60

Query: 61  APWCPSCQQTDSEWEAFAKNGEILQISVGKVDVIQEPGLSGRFFVTTLPAFFHAKDGIFR 120
           APWCPSCQQTDSEWEAFAKNGEILQISVGKVDVIQEPGLSGRFFVTTLPAFFHAKDGIFR
Sbjct: 61  APWCPSCQQTDSEWEAFAKNGEILQISVGKVDVIQEPGLSGRFFVTTLPAFFHAKDGIFR 120

Query: 121 RYRGPGIFEDLQNYILEKKWQSVEPLTGWKSPASLTMSGMAGLFSISGKIWHLHNYFTVT 180
           RYRGPGIFEDLQNYILEKKWQSVEPLTGWKSPASLTMSGMAGLFSISGKIWHLHNYFTVT
Sbjct: 121 RYRGPGIFEDLQNYILEKKWQSVEPLTGWKSPASLTMSGMAGLFSISGKIWHLHNYFTVT 180

Query: 181 LGIPAWCSYVFFVIATLVFGLFMGLVLVVISECFYVPLPRHLSERSEQNRRSEEAHRAEQ 240
           LGIPAWCSYVFFVIATLVFGLFMGLVLVVISECFYVPLPRHLSERSEQNRRSEEAHRAEQ
Sbjct: 181 LGIPAWCSYVFFVIATLVFGLFMGLVLVVISECFYVPLPRHLSERSEQNRRSEEAHRAEQ 240

Query: 241 LQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEEEEEDNLAAGVDEERSEANDQG 300
           LQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEEEEEDNLAAGVDEERSEANDQG
Sbjct: 241 LQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEEEEEDNLAAGVDEERSEANDQG 300

Query: 301 PPGEDGVTREEVEPEEAEEGISEQPCPADTEVVEDSLRQRKSQHADKGL 349
           PPGEDGVTREEVEPEEAEEGISEQPCPADTEVVEDSLRQRKSQHADKGL
Sbjct: 301 PPGEDGVTREEVEPEEAEEGISEQPCPADTEVVEDSLRQRKSQHADKGL 349


>gi|151101292 thioredoxin domain containing 1 [Homo sapiens]
          Length = 280

 Score =  222 bits (565), Expect = 4e-58
 Identities = 102/234 (43%), Positives = 152/234 (64%), Gaps = 12/234 (5%)

Query: 36  QSRVQPMTASNWTLVMEGEWMLKFYAPWCPSCQQTDSEWEAFAKNGEILQISVGKVDVIQ 95
           +S V+ +T  NW  ++EG+WM++FYAPWCP+CQ    EWE+FA+ GE L++++ KVDV +
Sbjct: 28  RSNVRVITDENWRELLEGDWMIEFYAPWCPACQNLQPEWESFAEWGEDLEVNIAKVDVTE 87

Query: 96  EPGLSGRFFVTTLPAFFHAKDGIFRRYRGPGIFEDLQNYILEKKWQSVEPLTGWKSPASL 155
           +PGLSGRF +T LP  +H KDG FRRY+GP   +D  N+I +K+W+S+EP++ W  P S+
Sbjct: 88  QPGLSGRFIITALPTIYHCKDGEFRRYQGPRTKKDFINFISDKEWKSIEPVSSWFGPGSV 147

Query: 156 TMSGMAGLFSISGKIWHLHNYFTVTLGIPAWCSYVFFVIATLVFGLFMGLVLVVISEC-- 213
            MS M+ LF +S  I   HNYF   LG+P W SY  F +ATL  GL +GL ++ +++C  
Sbjct: 148 LMSSMSALFQLSMWIRTCHNYFIEDLGLPVWGSYTVFALATLFSGLLLGLCMIFVADCLC 207

Query: 214 ---------FYVPLPRHLSERSEQNRRSEEAHRAEQLQDAEEEKDDSNEEENKD 258
                    +  P  + LSE ++  ++ EE   A++ +D  EE+ +S E  NKD
Sbjct: 208 PSKRRRPQPYPYPSKKLLSESAQPLKKVEEEQEADE-EDVSEEEAESKEGTNKD 260


>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 38/129 (29%), Positives = 58/129 (44%), Gaps = 19/129 (14%)

Query: 216  VPLPRHLSERSEQNRRSEEAHRAEQLQDAEEE------KDDSN--EEENKDSLVDDEEEK 267
            +PLP    E  E    +EEA   E+   A  E       D SN  E E K+  V++EEEK
Sbjct: 1217 MPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEK 1276

Query: 268  EDLGDE-----------DEAEEEEEEDNLAAGVDEERSEANDQGPPGEDGVTREEVEPEE 316
              + +E           +E E EEEED  A     +  +A+D+     +   ++E+E + 
Sbjct: 1277 PRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQP 1336

Query: 317  AEEGISEQP 325
              E + E+P
Sbjct: 1337 TREDVKEEP 1345



 Score = 38.9 bits (89), Expect = 0.007
 Identities = 30/101 (29%), Positives = 50/101 (49%), Gaps = 5/101 (4%)

Query: 234  EAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEEEEEDNLAAGVDEER 293
            +A R  ++Q++EE  +    +E+     + +EE+E   + +EAEE EEED  AA  +   
Sbjct: 1197 KAGRKPKIQESEETVEP---KEDMPLPEERKEEEEMQAEAEEAEEGEEED--AASSEVPA 1251

Query: 294  SEANDQGPPGEDGVTREEVEPEEAEEGISEQPCPADTEVVE 334
            +   D     E      EVE EE +  +SE+   ++ E  E
Sbjct: 1252 ASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQE 1292



 Score = 37.0 bits (84), Expect = 0.026
 Identities = 29/116 (25%), Positives = 52/116 (44%), Gaps = 10/116 (8%)

Query: 224  ERSEQNRRSEEAHRAEQLQDAEEEKDDSNE---EENKDSLVDDEEEKEDLGDEDEAEEEE 280
            E  E     EE   AE  Q+ + + DD ++   E  K   ++++  +ED+ +E       
Sbjct: 1292 ELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGV---- 1347

Query: 281  EEDNLAAGVDEERSEANDQGPPGEDGVTREEVEPEEAEEGISEQPCPADTEVVEDS 336
            +E  L A + + R +  D+    E  +  EE +P      +SEQ   ++ +  EDS
Sbjct: 1348 QESFLDANMQKSREKIKDK---EETELDSEEEQPSHDTSVVSEQMAGSEDDHEEDS 1400



 Score = 29.6 bits (65), Expect = 4.2
 Identities = 28/123 (22%), Positives = 49/123 (39%), Gaps = 16/123 (13%)

Query: 220  RHLSERSEQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEE 279
            + L E+  +    EE    E   DA  +K     ++ +++ +D EEE+        +E+ 
Sbjct: 1330 KELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQ- 1388

Query: 280  EEEDNLAAGVDEERSEANDQGPPGEDGVTREEVEPEEAEEGISEQPCPADTEVVEDSLRQ 339
                   AG +++           ED  T+EE+   + EE I       +T     SL Q
Sbjct: 1389 ------MAGSEDDHE---------EDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQ 1433

Query: 340  RKS 342
             +S
Sbjct: 1434 EES 1436


>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 38/129 (29%), Positives = 58/129 (44%), Gaps = 19/129 (14%)

Query: 216  VPLPRHLSERSEQNRRSEEAHRAEQLQDAEEE------KDDSN--EEENKDSLVDDEEEK 267
            +PLP    E  E    +EEA   E+   A  E       D SN  E E K+  V++EEEK
Sbjct: 1217 MPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEK 1276

Query: 268  EDLGDE-----------DEAEEEEEEDNLAAGVDEERSEANDQGPPGEDGVTREEVEPEE 316
              + +E           +E E EEEED  A     +  +A+D+     +   ++E+E + 
Sbjct: 1277 PRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQP 1336

Query: 317  AEEGISEQP 325
              E + E+P
Sbjct: 1337 TREDVKEEP 1345



 Score = 38.9 bits (89), Expect = 0.007
 Identities = 30/101 (29%), Positives = 50/101 (49%), Gaps = 5/101 (4%)

Query: 234  EAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEEEEEDNLAAGVDEER 293
            +A R  ++Q++EE  +    +E+     + +EE+E   + +EAEE EEED  AA  +   
Sbjct: 1197 KAGRKPKIQESEETVEP---KEDMPLPEERKEEEEMQAEAEEAEEGEEED--AASSEVPA 1251

Query: 294  SEANDQGPPGEDGVTREEVEPEEAEEGISEQPCPADTEVVE 334
            +   D     E      EVE EE +  +SE+   ++ E  E
Sbjct: 1252 ASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQE 1292



 Score = 37.0 bits (84), Expect = 0.026
 Identities = 29/116 (25%), Positives = 52/116 (44%), Gaps = 10/116 (8%)

Query: 224  ERSEQNRRSEEAHRAEQLQDAEEEKDDSNE---EENKDSLVDDEEEKEDLGDEDEAEEEE 280
            E  E     EE   AE  Q+ + + DD ++   E  K   ++++  +ED+ +E       
Sbjct: 1292 ELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGV---- 1347

Query: 281  EEDNLAAGVDEERSEANDQGPPGEDGVTREEVEPEEAEEGISEQPCPADTEVVEDS 336
            +E  L A + + R +  D+    E  +  EE +P      +SEQ   ++ +  EDS
Sbjct: 1348 QESFLDANMQKSREKIKDK---EETELDSEEEQPSHDTSVVSEQMAGSEDDHEEDS 1400



 Score = 29.6 bits (65), Expect = 4.2
 Identities = 28/123 (22%), Positives = 49/123 (39%), Gaps = 16/123 (13%)

Query: 220  RHLSERSEQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEE 279
            + L E+  +    EE    E   DA  +K     ++ +++ +D EEE+        +E+ 
Sbjct: 1330 KELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQ- 1388

Query: 280  EEEDNLAAGVDEERSEANDQGPPGEDGVTREEVEPEEAEEGISEQPCPADTEVVEDSLRQ 339
                   AG +++           ED  T+EE+   + EE I       +T     SL Q
Sbjct: 1389 ------MAGSEDDHE---------EDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQ 1433

Query: 340  RKS 342
             +S
Sbjct: 1434 EES 1436


>gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 38/129 (29%), Positives = 58/129 (44%), Gaps = 19/129 (14%)

Query: 216  VPLPRHLSERSEQNRRSEEAHRAEQLQDAEEE------KDDSN--EEENKDSLVDDEEEK 267
            +PLP    E  E    +EEA   E+   A  E       D SN  E E K+  V++EEEK
Sbjct: 1217 MPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEK 1276

Query: 268  EDLGDE-----------DEAEEEEEEDNLAAGVDEERSEANDQGPPGEDGVTREEVEPEE 316
              + +E           +E E EEEED  A     +  +A+D+     +   ++E+E + 
Sbjct: 1277 PRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQP 1336

Query: 317  AEEGISEQP 325
              E + E+P
Sbjct: 1337 TREDVKEEP 1345



 Score = 38.9 bits (89), Expect = 0.007
 Identities = 30/101 (29%), Positives = 50/101 (49%), Gaps = 5/101 (4%)

Query: 234  EAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEEEEEDNLAAGVDEER 293
            +A R  ++Q++EE  +    +E+     + +EE+E   + +EAEE EEED  AA  +   
Sbjct: 1197 KAGRKPKIQESEETVEP---KEDMPLPEERKEEEEMQAEAEEAEEGEEED--AASSEVPA 1251

Query: 294  SEANDQGPPGEDGVTREEVEPEEAEEGISEQPCPADTEVVE 334
            +   D     E      EVE EE +  +SE+   ++ E  E
Sbjct: 1252 ASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQE 1292



 Score = 37.0 bits (84), Expect = 0.026
 Identities = 29/116 (25%), Positives = 52/116 (44%), Gaps = 10/116 (8%)

Query: 224  ERSEQNRRSEEAHRAEQLQDAEEEKDDSNE---EENKDSLVDDEEEKEDLGDEDEAEEEE 280
            E  E     EE   AE  Q+ + + DD ++   E  K   ++++  +ED+ +E       
Sbjct: 1292 ELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGV---- 1347

Query: 281  EEDNLAAGVDEERSEANDQGPPGEDGVTREEVEPEEAEEGISEQPCPADTEVVEDS 336
            +E  L A + + R +  D+    E  +  EE +P      +SEQ   ++ +  EDS
Sbjct: 1348 QESFLDANMQKSREKIKDK---EETELDSEEEQPSHDTSVVSEQMAGSEDDHEEDS 1400



 Score = 29.6 bits (65), Expect = 4.2
 Identities = 28/123 (22%), Positives = 49/123 (39%), Gaps = 16/123 (13%)

Query: 220  RHLSERSEQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEE 279
            + L E+  +    EE    E   DA  +K     ++ +++ +D EEE+        +E+ 
Sbjct: 1330 KELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQ- 1388

Query: 280  EEEDNLAAGVDEERSEANDQGPPGEDGVTREEVEPEEAEEGISEQPCPADTEVVEDSLRQ 339
                   AG +++           ED  T+EE+   + EE I       +T     SL Q
Sbjct: 1389 ------MAGSEDDHE---------EDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQ 1433

Query: 340  RKS 342
             +S
Sbjct: 1434 EES 1436


>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
           sapiens]
          Length = 1152

 Score = 55.1 bits (131), Expect = 9e-08
 Identities = 39/113 (34%), Positives = 53/113 (46%), Gaps = 9/113 (7%)

Query: 220 RHLSERSEQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEE 279
           R    + E+N+  EE    E   + EEE+ D  EEE K+    +E E E++  E E EE 
Sbjct: 715 REQGHQKERNQEMEEGGEEEH-GEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEG 773

Query: 280 EEEDNLAAGVDEERSEANDQGP--------PGEDGVTREEVEPEEAEEGISEQ 324
           E +    AG +E+  E  DQG          GE+     EVE  E EEG  E+
Sbjct: 774 ERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGER 826



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 35/101 (34%), Positives = 46/101 (45%), Gaps = 4/101 (3%)

Query: 224 ERSEQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEEEEED 283
           E  E   R EE     +++  E E+     EE ++    +EEE E   +E E EEEE E 
Sbjct: 797 EEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGE- 855

Query: 284 NLAAGVDE-ERSEANDQGPPGEDGVTREEVEPEEAEEGISE 323
               G +E E  E  ++G  GE     EE E E  EEG  E
Sbjct: 856 --GKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGE 894



 Score = 49.3 bits (116), Expect = 5e-06
 Identities = 33/101 (32%), Positives = 49/101 (48%), Gaps = 5/101 (4%)

Query: 224 ERSEQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEEEEED 283
           E   + +  EE    E  ++ EE + +  EEE +    + EEE E  G+E+E E E EE+
Sbjct: 851 EEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEG---EGEEEGEGEGEEEEGEGEGEEE 907

Query: 284 NLAAGVDEE-RSEANDQGPPGEDGVTREEVEPEEAEEGISE 323
               G +EE   +  ++G  GE G   EE    E E+G  E
Sbjct: 908 GEGEGEEEEGEGKGEEEGEEGE-GEGEEEEGEGEGEDGEGE 947



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 30/106 (28%), Positives = 56/106 (52%), Gaps = 2/106 (1%)

Query: 220 RHLSERSEQNRRS-EEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEE 278
           + L+E+ E  +R  EE  + E+ Q  ++E++   EE  ++   + EEE+ D  +E+E E 
Sbjct: 694 KELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEG 753

Query: 279 EEEEDNLAAGVDEERSEANDQGPPGEDGVTREEVEPEEAEEGISEQ 324
           E +E+     V+ ER +   +    E+   +EE   EE ++G  E+
Sbjct: 754 EGKEEGEGEEVEGEREKEEGERKK-EERAGKEEKGEEEGDQGEGEE 798



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 32/101 (31%), Positives = 45/101 (44%), Gaps = 1/101 (0%)

Query: 224 ERSEQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEEEEED 283
           E  E      E    E+  + EEE+ +  EEE +    + E + E+ G+E E EEE EE 
Sbjct: 815 EGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEG 874

Query: 284 NLAAGVDEERSEANDQGPPGEDGVTREEVEPEEAEEGISEQ 324
                 +E   E  ++G  GE      E E EE  EG  E+
Sbjct: 875 EGEGEEEEGEGEGEEEG-EGEGEEEEGEGEGEEEGEGEGEE 914



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 36/111 (32%), Positives = 53/111 (47%), Gaps = 6/111 (5%)

Query: 220 RHLSERSEQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDE-EEKEDLGDEDEAEE 278
           R   E   +    E     E+ +  EEE +   EEE ++   ++E EE E  G+E+E E 
Sbjct: 826 REEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEG 885

Query: 279 EEEEDNLAAGVDEE-RSEANDQGP---PGEDGVTREEVEPEEAE-EGISEQ 324
           E EE+    G +EE   E  ++G      E+G  + E E EE E EG  E+
Sbjct: 886 EGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEE 936



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 34/106 (32%), Positives = 51/106 (48%), Gaps = 10/106 (9%)

Query: 224 ERSEQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEEEEED 283
           +R E+  +  E     + ++ E E++    E  K+     EE+ E+ GD+ E EEEE E 
Sbjct: 744 DREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETE- 802

Query: 284 NLAAGVDEERSEAND-QGPPGEDGV---TREEVEPE-EAEEGISEQ 324
               G  EE+ E  + +G   E+G      EE E E E EEG  E+
Sbjct: 803 ----GRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEE 844



 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 38/116 (32%), Positives = 53/116 (45%), Gaps = 18/116 (15%)

Query: 221 HLSERS-EQNRRSEEAH----RAEQLQDAEEEKDDSNEEENKDSLVDDEEEKED------ 269
           H  ER+ E     EE H      E  ++ EEEK+   +EE +   V+ E EKE+      
Sbjct: 719 HQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKE 778

Query: 270 --LGDEDEAEEE----EEEDNLAAGVDEERSEAND-QGPPGEDGVTREEVEPEEAE 318
              G E++ EEE    E E+    G  EE+ E  + +G   E+G    E E EE E
Sbjct: 779 ERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGE 834



 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 34/106 (32%), Positives = 47/106 (44%), Gaps = 6/106 (5%)

Query: 224 ERSEQNRRSEEAHRAEQLQDAEEEKDDSNEE-----ENKDSLVDDEEEKEDLGDEDEAEE 278
           E  E+    EE    E   + EE + +  EE     E ++   + EEE E  G+E+E E 
Sbjct: 860 EEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEG 919

Query: 279 EEEEDNLAAGVDEERSEANDQGPPGEDGVTREEVEPE-EAEEGISE 323
           + EE+      + E  E   +G  GE     EE E E E EEG  E
Sbjct: 920 KGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGE 965



 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 34/100 (34%), Positives = 46/100 (46%), Gaps = 7/100 (7%)

Query: 224  ERSEQNRRSEEAHRAEQLQDAE---EEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEEE 280
            E  E     EE     + +D E   EE++   E E ++   + EEE E  G+E E E EE
Sbjct: 924  EGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEE 983

Query: 281  EEDNLAAGVDEERSEANDQGPPGEDGVTREEVEPEEAEEG 320
            EE       +E   E  ++G   E+G    E E EE EEG
Sbjct: 984  EEGEGEGEEEEGEEEGEEEGEGEEEG----EGEGEEEEEG 1019



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 30/95 (31%), Positives = 44/95 (46%), Gaps = 1/95 (1%)

Query: 224  ERSEQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEEEEED 283
            E  E     EE     + ++ EEE ++  E E +     +EEE+ ++  E E EE E E 
Sbjct: 975  EEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEG 1034

Query: 284  NLAAGVDEERSEANDQGPPGEDGVTREEVEPEEAE 318
                G +EE  E   +G   E+   REE E EE +
Sbjct: 1035 EEEEG-EEEGEEREKEGEGEENRRNREEEEEEEGK 1068



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 35/103 (33%), Positives = 48/103 (46%), Gaps = 8/103 (7%)

Query: 222 LSERSEQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEK---EDLGDEDEAEE 278
           + E   +    EE    E+ +   EE++   EEE  +   ++E E+   E+ G+E E E 
Sbjct: 819 VEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEG 878

Query: 279 EEEEDNLAAGVDEERSEANDQGPPGEDGVTREEVEPE-EAEEG 320
           EEEE     G  EE  E   +   GE G   EE E E E EEG
Sbjct: 879 EEEE---GEGEGEEEGEGEGEEEEGE-GEGEEEGEGEGEEEEG 917



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 37/131 (28%), Positives = 59/131 (45%), Gaps = 11/131 (8%)

Query: 224  ERSEQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEK-----EDLGDEDEAEE 278
            E  E     EE     + ++ E E ++  E E ++   + EEE+     E+   E+E EE
Sbjct: 942  EDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEE 1001

Query: 279  EEEEDNLAAGVDEERSEANDQGP-PGEDGVTREEVEPEEAEEGISEQPCPADTEVVEDSL 337
            E E +    G  EE  E   +G   GE+G    E E EE EE   E+    +    E++ 
Sbjct: 1002 EGEGEEEGEGEGEEEEEGEVEGEVEGEEG--EGEGEEEEGEEEGEEREKEGEG---EENR 1056

Query: 338  RQRKSQHADKG 348
            R R+ +  ++G
Sbjct: 1057 RNREEEEEEEG 1067



 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 33/97 (34%), Positives = 42/97 (43%), Gaps = 4/97 (4%)

Query: 224 ERSEQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEEEEED 283
           E  E  R  EE  R ++ +  +EEK    EEE  D    +EEE E  G+E E   E E  
Sbjct: 762 EEVEGEREKEEGERKKEERAGKEEK---GEEEG-DQGEGEEEETEGRGEEKEEGGEVEGG 817

Query: 284 NLAAGVDEERSEANDQGPPGEDGVTREEVEPEEAEEG 320
            +  G  E   E  +     E+G   EE    E EEG
Sbjct: 818 EVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEG 854



 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 35/123 (28%), Positives = 52/123 (42%), Gaps = 14/123 (11%)

Query: 227  EQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEK-EDLGDEDEAEEEEEEDNL 285
            E+     E     + +  EEE +   EEE ++   + EEE+ E  G++ E E EEEE   
Sbjct: 896  EEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEW 955

Query: 286  AAGVDEERSEANDQGP-PGEDGV------------TREEVEPEEAEEGISEQPCPADTEV 332
                +E   E  ++G   GE+G               EE E E  EEG  E+    + E 
Sbjct: 956  EGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEE 1015

Query: 333  VED 335
             E+
Sbjct: 1016 EEE 1018



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 34/106 (32%), Positives = 49/106 (46%), Gaps = 10/106 (9%)

Query: 224 ERSEQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDE-----DEAEE 278
           E+ E  R+ EE    E+  + E ++ +  EEE +    + EE  E  G E      E EE
Sbjct: 769 EKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREE 828

Query: 279 EEEEDNLAAGVDEERSEANDQGPPGEDGVTREEVEPEEAEEGISEQ 324
           EEEE       +EE  E  ++   GE+     + E EE EEG  E+
Sbjct: 829 EEEEGE----GEEEEGEGEEEEGEGEEEEGEGKGE-EEGEEGEGEE 869



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 30/121 (24%), Positives = 58/121 (47%), Gaps = 10/121 (8%)

Query: 227 EQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEEEEEDNLA 286
           E+ +  ++  R E  +  E EK+ + +EE K    +++E+KE     ++  ++E    + 
Sbjct: 673 EREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKE----REQGHQKERNQEME 728

Query: 287 AGVDEERSEANDQGPPGEDGVTREEVEPEEAEEGISEQPCPADTEVVEDSLRQRKSQHAD 346
            G +EE  E  ++    E+    EE E E  EEG  E+    + E  ++   ++K + A 
Sbjct: 729 EGGEEEHGEGEEEEGDREE---EEEKEGEGKEEGEGEE---VEGEREKEEGERKKEERAG 782

Query: 347 K 347
           K
Sbjct: 783 K 783



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 36/105 (34%), Positives = 46/105 (43%), Gaps = 15/105 (14%)

Query: 234 EAHRAEQLQDAEEEKDDSNEEENKDSLVDDE-EEKEDLGDEDEAE--------EEEEEDN 284
           E    E   + EEE +   EEE  +   ++E EE E  G+E+E E        E EEE+ 
Sbjct: 894 EGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEG 953

Query: 285 LAAGVDEE-----RSEANDQGPPGEDGVTREEVEPE-EAEEGISE 323
              G +EE       E   +G  GE     EE E E E EEG  E
Sbjct: 954 EWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEE 998



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 27/96 (28%), Positives = 41/96 (42%), Gaps = 2/96 (2%)

Query: 224  ERSEQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEEEEED 283
            E  E     EE    E+  + E E+++  E E +    + E E E+   E+E EE E+E 
Sbjct: 991  EEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEG 1050

Query: 284  NLAAGVDEERSEANDQGPPGEDGVTREEVEPEEAEE 319
                       E  ++G   E G   EE E ++ EE
Sbjct: 1051 EGEENRRNREEEEEEEGKYQETG--EEENERQDGEE 1084



 Score = 38.9 bits (89), Expect = 0.007
 Identities = 26/98 (26%), Positives = 44/98 (44%), Gaps = 1/98 (1%)

Query: 224  ERSEQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEEEEED 283
            E   +    E     E+  + EEE +   EEE +  +  + E +E  G+ +E E EEE +
Sbjct: 985  EGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGE 1044

Query: 284  NLAAGVDEERSEANDQGPPGEDGVTREEVEPE-EAEEG 320
                  + E +  N +    E+G  +E  E E E ++G
Sbjct: 1045 EREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDG 1082



 Score = 37.7 bits (86), Expect = 0.015
 Identities = 33/101 (32%), Positives = 45/101 (44%), Gaps = 10/101 (9%)

Query: 227 EQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAE---EEEEED 283
           E+     E     + +  EEE +   EEE +     +EEE E  G+E+  E   E EEE+
Sbjct: 879 EEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGE--GEEEEGEGKGEEEGEEGEGEGEEEE 936

Query: 284 NLAAGVDEERSEANDQGP-PGEDGVTREEVEPEEAEEGISE 323
               G D E     ++G   GE+    EE E E  EEG  E
Sbjct: 937 GEGEGEDGEGEGEEEEGEWEGEE----EEGEGEGEEEGEGE 973



 Score = 37.7 bits (86), Expect = 0.015
 Identities = 29/101 (28%), Positives = 42/101 (41%), Gaps = 1/101 (0%)

Query: 224 ERSEQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEEEEED 283
           E   +    EE     + ++ E E ++  E E ++   + + E+E    E E EEEE E 
Sbjct: 880 EEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEG 939

Query: 284 NLAAGVDEERSEANDQGPPGEDGVTREEVEPE-EAEEGISE 323
               G  E   E  +     E+G    E E E E EEG  E
Sbjct: 940 EGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGE 980



 Score = 36.2 bits (82), Expect = 0.045
 Identities = 36/108 (33%), Positives = 54/108 (50%), Gaps = 20/108 (18%)

Query: 224 ERSEQNRRSEEAHRA----EQLQDAEE-EKDDSNEEENKDSLVDDEEEK----EDLGDED 274
           E+ E+++   E  R     ++L + EE +K D  E+E K+     ++E+    E+ G+E+
Sbjct: 675 EKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEE 734

Query: 275 EAE-EEEEEDNLAAGVDEERSEANDQGPPGEDGVTREEVEPE-EAEEG 320
             E EEEE D       EE  E   +G    +G   EEVE E E EEG
Sbjct: 735 HGEGEEEEGDR------EEEEEKEGEGKEEGEG---EEVEGEREKEEG 773


>gi|17975763 myelin transcription factor 1 [Homo sapiens]
          Length = 1121

 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 35/119 (29%), Positives = 63/119 (52%), Gaps = 14/119 (11%)

Query: 222 LSERSEQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEEEE 281
           L  +S ++  SEE+ + + +   EEE ++  EEE ++   ++EEE+E+  +E+E EEEEE
Sbjct: 235 LCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEE 294

Query: 282 EDNLAAGVDEERSEANDQGPPGEDGVTREEVEPEEAEEG------ISEQPCPADTEVVE 334
           E+      +EE  E  ++  P  D + +E+     A++        S  P P  + +VE
Sbjct: 295 EE------EEEEEEEEEEAAP--DVIFQEDTSHTSAQKAPELRGPESPSPKPEYSVIVE 345



 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 34/125 (27%), Positives = 57/125 (45%), Gaps = 12/125 (9%)

Query: 221 HLSERSEQNRRSEEAHRAEQLQ--DAEEEKDDSNEEEN-------KDSLVDDEEEKEDLG 271
           HL + + +   SEE  +   +Q  DAEE  + + E          +D+  ++  +++ + 
Sbjct: 196 HLLQEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGIL 255

Query: 272 DEDEAEEEEEEDNLAAGVDEERSEANDQGPPGEDGVTREEVEPEEAEEGISEQPCPADTE 331
             +E +EEEEE+      DEE  E  ++    E+    EE E EE EE   E+    D  
Sbjct: 256 SHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEE---EEEEEEEEEEEEEEEEEAAPDVI 312

Query: 332 VVEDS 336
             ED+
Sbjct: 313 FQEDT 317



 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 26/117 (22%), Positives = 51/117 (43%)

Query: 221 HLSERSEQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEEE 280
           H  E  E+    EE    E+ ++ EEE+++  EEE ++   ++EEE+E+    D   +E+
Sbjct: 257 HEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQED 316

Query: 281 EEDNLAAGVDEERSEANDQGPPGEDGVTREEVEPEEAEEGISEQPCPADTEVVEDSL 337
                A    E R   +    P    +     + ++ E+  S +    D   ++D +
Sbjct: 317 TSHTSAQKAPELRGPESPSPKPEYSVIVEVRSDDDKDEDTHSRKSTVTDESEMQDMM 373


>gi|239756368 PREDICTED: similar to acidic (leucine-rich) nuclear
           phosphoprotein 32 family, member B [Homo sapiens]
          Length = 272

 Score = 53.1 bits (126), Expect = 4e-07
 Identities = 29/100 (29%), Positives = 55/100 (55%), Gaps = 4/100 (4%)

Query: 224 ERSEQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDL---GDEDEAEEEE 280
           E  + + + +   + E+ ++ E+EKD  NE+  ++ L ++E+E ED+    D+DE  EEE
Sbjct: 174 EAPDSDAQVDGVDKEEEDEEGEDEKDXENEDGEEEELDEEEDEDEDVEGDDDKDEVSEEE 233

Query: 281 EEDNLAAGVDEERSEANDQGPPGEDGVTREEVEPEEAEEG 320
           EE  L    D+E  + +++      G  R+  E ++ E+G
Sbjct: 234 EEFGLDKDEDDEDEDEDEEEEESGKGENRKR-ETDDEEDG 272



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 28/99 (28%), Positives = 53/99 (53%), Gaps = 2/99 (2%)

Query: 239 EQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEEEEEDNLAAGVD--EERSEA 296
           ++  D++ + D  ++EE  +   D+++ + + G+E+E +EEE+ED    G D  +E SE 
Sbjct: 173 QEAPDSDAQVDGVDKEEEDEEGEDEKDXENEDGEEEELDEEEDEDEDVEGDDDKDEVSEE 232

Query: 297 NDQGPPGEDGVTREEVEPEEAEEGISEQPCPADTEVVED 335
            ++    +D    +E E EE EE    +    +T+  ED
Sbjct: 233 EEEFGLDKDEDDEDEDEDEEEEESGKGENRKRETDDEED 271



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 26/95 (27%), Positives = 44/95 (46%), Gaps = 2/95 (2%)

Query: 250 DSNEEENKDSLVDDEEEKEDLGDEDEAEEEEEEDNLAAGVDEERSEANDQGPPGEDGVTR 309
           D  ++E  DS  D + +  D  +EDE  E+E++     G +EE  E  D+    E    +
Sbjct: 169 DPEDQEAPDS--DAQVDGVDKEEEDEEGEDEKDXENEDGEEEELDEEEDEDEDVEGDDDK 226

Query: 310 EEVEPEEAEEGISEQPCPADTEVVEDSLRQRKSQH 344
           +EV  EE E G+ +     D +  E+     K ++
Sbjct: 227 DEVSEEEEEFGLDKDEDDEDEDEDEEEEESGKGEN 261



 Score = 36.2 bits (82), Expect = 0.045
 Identities = 17/62 (27%), Positives = 34/62 (54%)

Query: 222 LSERSEQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEEEE 281
           L E  +++   E     +++ + EEE     +E+++D   D+EEE+   G+  + E ++E
Sbjct: 210 LDEEEDEDEDVEGDDDKDEVSEEEEEFGLDKDEDDEDEDEDEEEEESGKGENRKRETDDE 269

Query: 282 ED 283
           ED
Sbjct: 270 ED 271



 Score = 33.9 bits (76), Expect = 0.22
 Identities = 23/71 (32%), Positives = 39/71 (54%), Gaps = 3/71 (4%)

Query: 223 SERSEQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSL-VDDEEEKEDLGDEDEAEEEEE 281
           +E  E+    EE    E ++  +++KD+ +EEE +  L  D+++E ED  DE+E E  + 
Sbjct: 202 NEDGEEEELDEEEDEDEDVE-GDDDKDEVSEEEEEFGLDKDEDDEDEDE-DEEEEESGKG 259

Query: 282 EDNLAAGVDEE 292
           E+      DEE
Sbjct: 260 ENRKRETDDEE 270


>gi|239750893 PREDICTED: similar to acidic (leucine-rich) nuclear
           phosphoprotein 32 family, member B [Homo sapiens]
          Length = 272

 Score = 53.1 bits (126), Expect = 4e-07
 Identities = 29/100 (29%), Positives = 55/100 (55%), Gaps = 4/100 (4%)

Query: 224 ERSEQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDL---GDEDEAEEEE 280
           E  + + + +   + E+ ++ E+EKD  NE+  ++ L ++E+E ED+    D+DE  EEE
Sbjct: 174 EAPDSDAQVDGVDKEEEDEEGEDEKDXENEDGEEEELDEEEDEDEDVEGDDDKDEVSEEE 233

Query: 281 EEDNLAAGVDEERSEANDQGPPGEDGVTREEVEPEEAEEG 320
           EE  L    D+E  + +++      G  R+  E ++ E+G
Sbjct: 234 EEFGLDKDEDDEDEDEDEEEEESGKGENRKR-ETDDEEDG 272



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 28/99 (28%), Positives = 53/99 (53%), Gaps = 2/99 (2%)

Query: 239 EQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEEEEEDNLAAGVD--EERSEA 296
           ++  D++ + D  ++EE  +   D+++ + + G+E+E +EEE+ED    G D  +E SE 
Sbjct: 173 QEAPDSDAQVDGVDKEEEDEEGEDEKDXENEDGEEEELDEEEDEDEDVEGDDDKDEVSEE 232

Query: 297 NDQGPPGEDGVTREEVEPEEAEEGISEQPCPADTEVVED 335
            ++    +D    +E E EE EE    +    +T+  ED
Sbjct: 233 EEEFGLDKDEDDEDEDEDEEEEESGKGENRKRETDDEED 271



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 26/95 (27%), Positives = 44/95 (46%), Gaps = 2/95 (2%)

Query: 250 DSNEEENKDSLVDDEEEKEDLGDEDEAEEEEEEDNLAAGVDEERSEANDQGPPGEDGVTR 309
           D  ++E  DS  D + +  D  +EDE  E+E++     G +EE  E  D+    E    +
Sbjct: 169 DPEDQEAPDS--DAQVDGVDKEEEDEEGEDEKDXENEDGEEEELDEEEDEDEDVEGDDDK 226

Query: 310 EEVEPEEAEEGISEQPCPADTEVVEDSLRQRKSQH 344
           +EV  EE E G+ +     D +  E+     K ++
Sbjct: 227 DEVSEEEEEFGLDKDEDDEDEDEDEEEEESGKGEN 261



 Score = 36.2 bits (82), Expect = 0.045
 Identities = 17/62 (27%), Positives = 34/62 (54%)

Query: 222 LSERSEQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEEEE 281
           L E  +++   E     +++ + EEE     +E+++D   D+EEE+   G+  + E ++E
Sbjct: 210 LDEEEDEDEDVEGDDDKDEVSEEEEEFGLDKDEDDEDEDEDEEEEESGKGENRKRETDDE 269

Query: 282 ED 283
           ED
Sbjct: 270 ED 271



 Score = 33.9 bits (76), Expect = 0.22
 Identities = 23/71 (32%), Positives = 39/71 (54%), Gaps = 3/71 (4%)

Query: 223 SERSEQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSL-VDDEEEKEDLGDEDEAEEEEE 281
           +E  E+    EE    E ++  +++KD+ +EEE +  L  D+++E ED  DE+E E  + 
Sbjct: 202 NEDGEEEELDEEEDEDEDVE-GDDDKDEVSEEEEEFGLDKDEDDEDEDE-DEEEEESGKG 259

Query: 282 EDNLAAGVDEE 292
           E+      DEE
Sbjct: 260 ENRKRETDDEE 270


>gi|42794771 thioredoxin domain containing 5 isoform 1 precursor
           [Homo sapiens]
          Length = 432

 Score = 53.1 bits (126), Expect = 4e-07
 Identities = 39/125 (31%), Positives = 58/125 (46%), Gaps = 8/125 (6%)

Query: 27  PEEAALPPEQSRVQP----MTASNWTL-VMEGEWMLKFYAPWCPSCQQTDSEWEAFAKNG 81
           PE    PP    ++     ++ASN+ L V +G+  +KF+APWC  C+     WE  A   
Sbjct: 175 PEPEVEPPSAPELKQGLYELSASNFELHVAQGDHFIKFFAPWCGHCKALAPTWEQLALGL 234

Query: 82  EILQ-ISVGKVDVIQEPGLSGRFFVTTLPAFFHAKDG-IFRRYRGPGIFEDLQNYILEKK 139
           E  + + +GKVD  Q   L     V   P     +DG    +Y+G    E L+ Y+ E +
Sbjct: 235 EHSETVKIGKVDCTQHYELCSGNQVRGYPTLLWFRDGKKVDQYKGKRDLESLREYV-ESQ 293

Query: 140 WQSVE 144
            Q  E
Sbjct: 294 LQRTE 298



 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 48/183 (26%), Positives = 77/183 (42%), Gaps = 22/183 (12%)

Query: 3   GGRCGPQLTALLAAWIAAVAATAGPEEAALPPEQSRVQPMTASNWTL-VMEGEWMLKFYA 61
           GGR G +     AA  AA    A   E    P    +   TA  +T  +      + F+A
Sbjct: 31  GGRWGARAQEAAAA--AADGPPAADGEDGQDPHSKHLY--TADMFTHGIQSAAHFVMFFA 86

Query: 62  PWCPSCQQTDSEWEAFA---KNGEILQISVGKV------DVIQEPGLSGRFFVTTLPAFF 112
           PWC  CQ+    W        + E  ++ V KV      DV    G+ G     TL  F 
Sbjct: 87  PWCGHCQRLQPTWNDLGDKYNSMEDAKVYVAKVDCTAHSDVCSAQGVRG---YPTLKLFK 143

Query: 113 HAKDGIFRRYRGPGIFEDLQNYILEK-KWQSVEPLTGWKSPASLTMSGMAGLFSISGKIW 171
             ++ +  +Y+GP  F+ L+N++L+    + V P    + P++  +    GL+ +S   +
Sbjct: 144 PGQEAV--KYQGPRDFQTLENWMLQTLNEEPVTPEPEVEPPSAPELK--QGLYELSASNF 199

Query: 172 HLH 174
            LH
Sbjct: 200 ELH 202



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 29/102 (28%), Positives = 45/102 (44%), Gaps = 8/102 (7%)

Query: 24  TAGPEEA---ALPPEQSR--VQPMTASNWT-LVMEGEWMLKFYAPWCPSCQQTDSEWEAF 77
           T  P EA   A  PE  +  V  +T +N+   + EG   +KFYAPWC  C+     WE  
Sbjct: 304 TVTPSEAPVLAAEPEADKGTVLALTENNFDDTIAEGITFIKFYAPWCGHCKTLAPTWEEL 363

Query: 78  AKN--GEILQISVGKVDVIQEPGLSGRFFVTTLPAFFHAKDG 117
           +K     +  + + +VD   E  +  ++ V   P     + G
Sbjct: 364 SKKEFPGLAGVKIAEVDCTAERNICSKYSVRGYPTLLLFRGG 405


>gi|224493972 thioredoxin domain containing 5 isoform 3 [Homo
           sapiens]
          Length = 324

 Score = 53.1 bits (126), Expect = 4e-07
 Identities = 39/125 (31%), Positives = 58/125 (46%), Gaps = 8/125 (6%)

Query: 27  PEEAALPPEQSRVQP----MTASNWTL-VMEGEWMLKFYAPWCPSCQQTDSEWEAFAKNG 81
           PE    PP    ++     ++ASN+ L V +G+  +KF+APWC  C+     WE  A   
Sbjct: 67  PEPEVEPPSAPELKQGLYELSASNFELHVAQGDHFIKFFAPWCGHCKALAPTWEQLALGL 126

Query: 82  EILQ-ISVGKVDVIQEPGLSGRFFVTTLPAFFHAKDG-IFRRYRGPGIFEDLQNYILEKK 139
           E  + + +GKVD  Q   L     V   P     +DG    +Y+G    E L+ Y+ E +
Sbjct: 127 EHSETVKIGKVDCTQHYELCSGNQVRGYPTLLWFRDGKKVDQYKGKRDLESLREYV-ESQ 185

Query: 140 WQSVE 144
            Q  E
Sbjct: 186 LQRTE 190



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 29/102 (28%), Positives = 45/102 (44%), Gaps = 8/102 (7%)

Query: 24  TAGPEEA---ALPPEQSR--VQPMTASNWT-LVMEGEWMLKFYAPWCPSCQQTDSEWEAF 77
           T  P EA   A  PE  +  V  +T +N+   + EG   +KFYAPWC  C+     WE  
Sbjct: 196 TVTPSEAPVLAAEPEADKGTVLALTENNFDDTIAEGITFIKFYAPWCGHCKTLAPTWEEL 255

Query: 78  AKN--GEILQISVGKVDVIQEPGLSGRFFVTTLPAFFHAKDG 117
           +K     +  + + +VD   E  +  ++ V   P     + G
Sbjct: 256 SKKEFPGLAGVKIAEVDCTAERNICSKYSVRGYPTLLLFRGG 297


>gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 family,
           member B [Homo sapiens]
          Length = 251

 Score = 53.1 bits (126), Expect = 4e-07
 Identities = 26/82 (31%), Positives = 48/82 (58%)

Query: 239 EQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEEEEEDNLAAGVDEERSEAND 298
           ++  D++ E D  +EEE  +   D+E+E ++ G+E+E +EE++ED    G +++   + +
Sbjct: 153 QEAPDSDAEVDGVDEEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDEDDDEVSEE 212

Query: 299 QGPPGEDGVTREEVEPEEAEEG 320
           +   G D    +E E EE EEG
Sbjct: 213 EEEFGLDEEDEDEDEDEEEEEG 234



 Score = 53.1 bits (126), Expect = 4e-07
 Identities = 33/88 (37%), Positives = 48/88 (54%), Gaps = 5/88 (5%)

Query: 233 EEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEEEEEDNLAAGVDEE 292
           +E    E+ +D E+E D+  EEE  D   D++E+ E   D+DE  EEEEE     G+DEE
Sbjct: 166 DEEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDEDDDEVSEEEEE----FGLDEE 221

Query: 293 RSEANDQGPPGEDGVTREEVEPEEAEEG 320
             E  D+    E+G   E+ + E  +EG
Sbjct: 222 -DEDEDEDEEEEEGGKGEKRKRETDDEG 248



 Score = 48.5 bits (114), Expect = 9e-06
 Identities = 23/77 (29%), Positives = 42/77 (54%)

Query: 224 ERSEQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEEEEED 283
           E  E     ++    E+  D E+++D+  E +  D  V +EEE+  L +EDE E+E+EE+
Sbjct: 172 EEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDEDDDEVSEEEEEFGLDEEDEDEDEDEEE 231

Query: 284 NLAAGVDEERSEANDQG 300
                 ++ + E +D+G
Sbjct: 232 EEGGKGEKRKRETDDEG 248



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 32/102 (31%), Positives = 51/102 (50%), Gaps = 5/102 (4%)

Query: 250 DSNEEENKDSLVDDEEEKEDLGDEDEAEEEEEEDNLAAGVDEERSEANDQGPPGEDGVTR 309
           D  ++E  DS  D E +  D  +EDE  E+EE+++   G +EE  E +D+    E     
Sbjct: 149 DREDQEAPDS--DAEVDGVDEEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDEDD 206

Query: 310 EEVEPEEAEEGISEQPCPADTEVVED---SLRQRKSQHADKG 348
           +EV  EE E G+ E+    D +  E+      +RK +  D+G
Sbjct: 207 DEVSEEEEEFGLDEEDEDEDEDEEEEEGGKGEKRKRETDDEG 248



 Score = 31.6 bits (70), Expect = 1.1
 Identities = 20/69 (28%), Positives = 33/69 (47%), Gaps = 9/69 (13%)

Query: 224 ERSEQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDED--------- 274
           E  E+    EE    E ++  E++ + S EEE      +DE+E ED  +E+         
Sbjct: 183 EDGEEEEFDEEDDEDEDVEGDEDDDEVSEEEEEFGLDEEDEDEDEDEEEEEGGKGEKRKR 242

Query: 275 EAEEEEEED 283
           E ++E E+D
Sbjct: 243 ETDDEGEDD 251



 Score = 31.6 bits (70), Expect = 1.1
 Identities = 18/65 (27%), Positives = 36/65 (55%), Gaps = 4/65 (6%)

Query: 224 ERSEQNRRSEEAHRAEQLQD----AEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEE 279
           E  E +   +E    E  +D    +EEE++   +EE++D   D+EEE+   G++ + E +
Sbjct: 186 EEEEFDEEDDEDEDVEGDEDDDEVSEEEEEFGLDEEDEDEDEDEEEEEGGKGEKRKRETD 245

Query: 280 EEEDN 284
           +E ++
Sbjct: 246 DEGED 250


>gi|221219020 NYD-SP11 protein [Homo sapiens]
          Length = 2873

 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 36/119 (30%), Positives = 59/119 (49%), Gaps = 4/119 (3%)

Query: 218  LPRHLSERSEQNRRSEEAHR-AEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEA 276
            L R   +R E  R  +   + + Q+ + E E+  S E E   SL+D+ E++E L  E+E 
Sbjct: 2193 LKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEME---SLLDELEKQESLSSEEEE 2249

Query: 277  EEEEEEDNLAAGVDEERSEANDQGPPGEDGVTREEVEPEEAEEGISEQPCPADTEVVED 335
            E EEEE+     V EE  E  ++    E  V +EE E ++ ++   ++      EV E+
Sbjct: 2250 EREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEE 2308



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 32/126 (25%), Positives = 60/126 (47%), Gaps = 4/126 (3%)

Query: 217  PLPRHLSERSEQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEA 276
            P  +  S+  E       +   E L D  E+++  + EE ++   ++E E+E++ +E+E 
Sbjct: 2209 PKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEE 2268

Query: 277  EEEEEEDNLAAGVDEERSEANDQGPPGEDGVTREEVEPEEAEEGISEQPCPADTEVVEDS 336
             +EEEE        EE  +   +    ++ V  +E   EE EE +SE+    +TE + D 
Sbjct: 2269 RKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEE----ETESLSDE 2324

Query: 337  LRQRKS 342
              + +S
Sbjct: 2325 EEEEES 2330



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 20/65 (30%), Positives = 40/65 (61%), Gaps = 3/65 (4%)

Query: 220  RHLSERSEQNRRSEEAHRAEQLQDAEE---EKDDSNEEENKDSLVDDEEEKEDLGDEDEA 276
            + + +  E+ ++ ++  + E++Q+ EE   EK++   EE  +SL D+EEE+E    E+E 
Sbjct: 2278 KQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEV 2337

Query: 277  EEEEE 281
            + E+E
Sbjct: 2338 DREKE 2342



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 29/105 (27%), Positives = 52/105 (49%), Gaps = 15/105 (14%)

Query: 222  LSERSEQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEE--------------EK 267
            LS   E+ R  EE    E++++ EEE+ +  E E K    ++EE              EK
Sbjct: 2243 LSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEK 2302

Query: 268  EDLGDE-DEAEEEEEEDNLAAGVDEERSEANDQGPPGEDGVTREE 311
            E++ +E +E   EEE ++L+   +EE S + ++    E  + ++E
Sbjct: 2303 EEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKE 2347



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 31/116 (26%), Positives = 55/116 (47%), Gaps = 17/116 (14%)

Query: 222  LSERSEQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEEEE 281
            L E  +Q   S E     + ++  EE++   EEE        E ++E+ G+E + E+EEE
Sbjct: 2234 LDELEKQESLSSEEEEEREEEEEREEEEVREEEE--------ERKEEEEGEEKQVEKEEE 2285

Query: 282  EDNLAAGVDEERSEANDQGPPGEDGVTREEVEPEEAEEGIS-----EQPCPADTEV 332
            E       ++++ E  ++    E+   +EE+  EE  E +S     E+ C  + EV
Sbjct: 2286 EKK-KKKKEKKKEEVQEKEEVFEE---KEEIMSEEETESLSDEEEEEESCSLEEEV 2337



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 25/93 (26%), Positives = 47/93 (50%), Gaps = 1/93 (1%)

Query: 224  ERSEQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEEEEED 283
            ER E+  R EE  R E+ ++ +EE++   ++  K+     +++KE   +E + +EE  E+
Sbjct: 2250 EREEEEEREEEEVREEE-EERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEE 2308

Query: 284  NLAAGVDEERSEANDQGPPGEDGVTREEVEPEE 316
                  +EE    +D+    E     EEV+ E+
Sbjct: 2309 KEEIMSEEETESLSDEEEEEESCSLEEEVDREK 2341


>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
          Length = 770

 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 37/109 (33%), Positives = 53/109 (48%), Gaps = 11/109 (10%)

Query: 226 SEQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAE----EEEE 281
           SE+   S E+  AE    +EEE+++  EEE + S  ++ EE+E+  +E+E E     EE 
Sbjct: 260 SERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEA 319

Query: 282 EDNLAAGV-------DEERSEANDQGPPGEDGVTREEVEPEEAEEGISE 323
            +  A  V       DEER   N      E    R+  E EEAEE + E
Sbjct: 320 SEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGE 368



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 31/115 (26%), Positives = 53/115 (46%), Gaps = 3/115 (2%)

Query: 219 PRHLSERSE--QNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEA 276
           PR   ER E    R+  +  + E+ +D   +  D ++ E K S  +    +   G E+E 
Sbjct: 224 PRPPRERFELGDGRKPVKEEKMEE-RDLLSDLQDISDSERKTSSAESSSAESGSGSEEEE 282

Query: 277 EEEEEEDNLAAGVDEERSEANDQGPPGEDGVTREEVEPEEAEEGISEQPCPADTE 331
           EEEEEE+   +  +E   E  ++    E+  +  E   E++ E +SE+    D E
Sbjct: 283 EEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEE 337



 Score = 28.9 bits (63), Expect = 7.2
 Identities = 18/66 (27%), Positives = 29/66 (43%), Gaps = 5/66 (7%)

Query: 227 EQNRRSEEAHRAE-----QLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEEEE 281
           E+ RR E+  +AE        D + ++D   E E +D  ++          ED  E+  E
Sbjct: 19  EKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRGE 78

Query: 282 EDNLAA 287
           ED+  A
Sbjct: 79  EDDSLA 84


>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
          Length = 780

 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 37/109 (33%), Positives = 53/109 (48%), Gaps = 11/109 (10%)

Query: 226 SEQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAE----EEEE 281
           SE+   S E+  AE    +EEE+++  EEE + S  ++ EE+E+  +E+E E     EE 
Sbjct: 270 SERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEA 329

Query: 282 EDNLAAGV-------DEERSEANDQGPPGEDGVTREEVEPEEAEEGISE 323
            +  A  V       DEER   N      E    R+  E EEAEE + E
Sbjct: 330 SEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGE 378



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 31/115 (26%), Positives = 53/115 (46%), Gaps = 3/115 (2%)

Query: 219 PRHLSERSE--QNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEA 276
           PR   ER E    R+  +  + E+ +D   +  D ++ E K S  +    +   G E+E 
Sbjct: 234 PRPPRERFELGDGRKPVKEEKMEE-RDLLSDLQDISDSERKTSSAESSSAESGSGSEEEE 292

Query: 277 EEEEEEDNLAAGVDEERSEANDQGPPGEDGVTREEVEPEEAEEGISEQPCPADTE 331
           EEEEEE+   +  +E   E  ++    E+  +  E   E++ E +SE+    D E
Sbjct: 293 EEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEE 347



 Score = 28.9 bits (63), Expect = 7.2
 Identities = 18/66 (27%), Positives = 29/66 (43%), Gaps = 5/66 (7%)

Query: 227 EQNRRSEEAHRAE-----QLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEEEE 281
           E+ RR E+  +AE        D + ++D   E E +D  ++          ED  E+  E
Sbjct: 19  EKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRGE 78

Query: 282 EDNLAA 287
           ED+  A
Sbjct: 79  EDDSLA 84


>gi|105990539 neurofilament, light polypeptide 68kDa [Homo sapiens]
          Length = 543

 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 32/92 (34%), Positives = 52/92 (56%), Gaps = 2/92 (2%)

Query: 235 AHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEEEE-EDNLAAGVDEER 293
           +H  E+  + EE  + +  EE KD    + E +E+  D++EAEEEE  E+  AA  + E 
Sbjct: 445 SHVQEEQIEVEETIEAAKAEEAKDEPPSEGEAEEEEKDKEEAEEEEAAEEEEAAKEESEE 504

Query: 294 SEANDQGPPGEDGVTREEVEPEEAE-EGISEQ 324
           ++  ++G  GE+G   +E E EE + EG  E+
Sbjct: 505 AKEEEEGGEGEEGEETKEAEEEEKKVEGAGEE 536



 Score = 35.4 bits (80), Expect = 0.077
 Identities = 20/66 (30%), Positives = 31/66 (46%)

Query: 217 PLPRHLSERSEQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEA 276
           P      E  +    +EE   AE+ + A+EE +++ EEE      + EE KE   +E + 
Sbjct: 471 PSEGEAEEEEKDKEEAEEEEAAEEEEAAKEESEEAKEEEEGGEGEEGEETKEAEEEEKKV 530

Query: 277 EEEEEE 282
           E   EE
Sbjct: 531 EGAGEE 536



 Score = 31.6 bits (70), Expect = 1.1
 Identities = 17/70 (24%), Positives = 33/70 (47%)

Query: 279 EEEEDNLAAGVDEERSEANDQGPPGEDGVTREEVEPEEAEEGISEQPCPADTEVVEDSLR 338
           +EE+  +   ++  ++E     PP E     EE + EEAEE  + +   A  E  E++  
Sbjct: 448 QEEQIEVEETIEAAKAEEAKDEPPSEGEAEEEEKDKEEAEEEEAAEEEEAAKEESEEAKE 507

Query: 339 QRKSQHADKG 348
           + +    ++G
Sbjct: 508 EEEGGEGEEG 517


>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           9 [Homo sapiens]
          Length = 771

 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 37/109 (33%), Positives = 53/109 (48%), Gaps = 11/109 (10%)

Query: 226 SEQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAE----EEEE 281
           SE+   S E+  AE    +EEE+++  EEE + S  ++ EE+E+  +E+E E     EE 
Sbjct: 261 SERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEA 320

Query: 282 EDNLAAGV-------DEERSEANDQGPPGEDGVTREEVEPEEAEEGISE 323
            +  A  V       DEER   N      E    R+  E EEAEE + E
Sbjct: 321 SEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGE 369



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 31/115 (26%), Positives = 53/115 (46%), Gaps = 3/115 (2%)

Query: 219 PRHLSERSE--QNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEA 276
           PR   ER E    R+  +  + E+ +D   +  D ++ E K S  +    +   G E+E 
Sbjct: 225 PRPPRERFELGDGRKPVKEEKMEE-RDLLSDLQDISDSERKTSSAESSSAESGSGSEEEE 283

Query: 277 EEEEEEDNLAAGVDEERSEANDQGPPGEDGVTREEVEPEEAEEGISEQPCPADTE 331
           EEEEEE+   +  +E   E  ++    E+  +  E   E++ E +SE+    D E
Sbjct: 284 EEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEE 338



 Score = 29.3 bits (64), Expect = 5.5
 Identities = 28/127 (22%), Positives = 51/127 (40%), Gaps = 19/127 (14%)

Query: 227 EQNRRSEEAHRAE-----QLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEE-E 280
           E+ RR E+  +AE        D + ++D   E E +D  ++          ED  E+  E
Sbjct: 19  EKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRGE 78

Query: 281 EEDNLAAGVDEERSEANDQGPPGEDGVTREEVEPEEAEEGISEQPCPADTEVVEDSLRQR 340
           E+D+LA    ++ S              +E+V   + E+   ++      +  E   R+R
Sbjct: 79  EDDSLAIKPPQQMSR-------------KEKVHHRKDEKRKEKKHARVKEKEREHERRKR 125

Query: 341 KSQHADK 347
             +  DK
Sbjct: 126 HREEQDK 132


>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           8 [Homo sapiens]
          Length = 780

 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 37/109 (33%), Positives = 53/109 (48%), Gaps = 11/109 (10%)

Query: 226 SEQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAE----EEEE 281
           SE+   S E+  AE    +EEE+++  EEE + S  ++ EE+E+  +E+E E     EE 
Sbjct: 270 SERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEA 329

Query: 282 EDNLAAGV-------DEERSEANDQGPPGEDGVTREEVEPEEAEEGISE 323
            +  A  V       DEER   N      E    R+  E EEAEE + E
Sbjct: 330 SEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGE 378



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 31/115 (26%), Positives = 53/115 (46%), Gaps = 3/115 (2%)

Query: 219 PRHLSERSE--QNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEA 276
           PR   ER E    R+  +  + E+ +D   +  D ++ E K S  +    +   G E+E 
Sbjct: 234 PRPPRERFELGDGRKPVKEEKMEE-RDLLSDLQDISDSERKTSSAESSSAESGSGSEEEE 292

Query: 277 EEEEEEDNLAAGVDEERSEANDQGPPGEDGVTREEVEPEEAEEGISEQPCPADTE 331
           EEEEEE+   +  +E   E  ++    E+  +  E   E++ E +SE+    D E
Sbjct: 293 EEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEE 347



 Score = 29.3 bits (64), Expect = 5.5
 Identities = 28/127 (22%), Positives = 51/127 (40%), Gaps = 19/127 (14%)

Query: 227 EQNRRSEEAHRAE-----QLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEE-E 280
           E+ RR E+  +AE        D + ++D   E E +D  ++          ED  E+  E
Sbjct: 19  EKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRGE 78

Query: 281 EEDNLAAGVDEERSEANDQGPPGEDGVTREEVEPEEAEEGISEQPCPADTEVVEDSLRQR 340
           E+D+LA    ++ S              +E+V   + E+   ++      +  E   R+R
Sbjct: 79  EDDSLAIKPPQQMSR-------------KEKVHHRKDEKRKEKKHARVKEKEREHERRKR 125

Query: 341 KSQHADK 347
             +  DK
Sbjct: 126 HREEQDK 132


>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           5 [Homo sapiens]
          Length = 748

 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 37/109 (33%), Positives = 53/109 (48%), Gaps = 11/109 (10%)

Query: 226 SEQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAE----EEEE 281
           SE+   S E+  AE    +EEE+++  EEE + S  ++ EE+E+  +E+E E     EE 
Sbjct: 238 SERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEA 297

Query: 282 EDNLAAGV-------DEERSEANDQGPPGEDGVTREEVEPEEAEEGISE 323
            +  A  V       DEER   N      E    R+  E EEAEE + E
Sbjct: 298 SEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGE 346



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 31/115 (26%), Positives = 53/115 (46%), Gaps = 3/115 (2%)

Query: 219 PRHLSERSE--QNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEA 276
           PR   ER E    R+  +  + E+ +D   +  D ++ E K S  +    +   G E+E 
Sbjct: 202 PRPPRERFELGDGRKPVKEEKMEE-RDLLSDLQDISDSERKTSSAESSSAESGSGSEEEE 260

Query: 277 EEEEEEDNLAAGVDEERSEANDQGPPGEDGVTREEVEPEEAEEGISEQPCPADTE 331
           EEEEEE+   +  +E   E  ++    E+  +  E   E++ E +SE+    D E
Sbjct: 261 EEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEE 315


>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           4 [Homo sapiens]
          Length = 737

 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 37/109 (33%), Positives = 53/109 (48%), Gaps = 11/109 (10%)

Query: 226 SEQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAE----EEEE 281
           SE+   S E+  AE    +EEE+++  EEE + S  ++ EE+E+  +E+E E     EE 
Sbjct: 227 SERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEA 286

Query: 282 EDNLAAGV-------DEERSEANDQGPPGEDGVTREEVEPEEAEEGISE 323
            +  A  V       DEER   N      E    R+  E EEAEE + E
Sbjct: 287 SEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGE 335



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 31/115 (26%), Positives = 53/115 (46%), Gaps = 3/115 (2%)

Query: 219 PRHLSERSE--QNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEA 276
           PR   ER E    R+  +  + E+ +D   +  D ++ E K S  +    +   G E+E 
Sbjct: 191 PRPPRERFELGDGRKPVKEEKMEE-RDLLSDLQDISDSERKTSSAESSSAESGSGSEEEE 249

Query: 277 EEEEEEDNLAAGVDEERSEANDQGPPGEDGVTREEVEPEEAEEGISEQPCPADTE 331
           EEEEEE+   +  +E   E  ++    E+  +  E   E++ E +SE+    D E
Sbjct: 250 EEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEE 304


>gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           3 [Homo sapiens]
          Length = 526

 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 37/109 (33%), Positives = 53/109 (48%), Gaps = 11/109 (10%)

Query: 226 SEQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAE----EEEE 281
           SE+   S E+  AE    +EEE+++  EEE + S  ++ EE+E+  +E+E E     EE 
Sbjct: 16  SERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEA 75

Query: 282 EDNLAAGV-------DEERSEANDQGPPGEDGVTREEVEPEEAEEGISE 323
            +  A  V       DEER   N      E    R+  E EEAEE + E
Sbjct: 76  SEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGE 124



 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 24/90 (26%), Positives = 42/90 (46%)

Query: 242 QDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEEEEEDNLAAGVDEERSEANDQGP 301
           +D   +  D ++ E K S  +    +   G E+E EEEEEE+   +  +E   E  ++  
Sbjct: 4   RDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEE 63

Query: 302 PGEDGVTREEVEPEEAEEGISEQPCPADTE 331
             E+  +  E   E++ E +SE+    D E
Sbjct: 64  EEEETGSNSEEASEQSAEEVSEEEMSEDEE 93



 Score = 32.3 bits (72), Expect = 0.65
 Identities = 28/94 (29%), Positives = 39/94 (41%), Gaps = 20/94 (21%)

Query: 261 VDDEEEKEDLGDEDEAEE----EEEEDNLAAGVDEERSEANDQGPPGEDGVTREEVEPEE 316
           + D E K    +   AE     EEEE        EE  E  ++G   E+    EE E EE
Sbjct: 13  ISDSERKTSSAESSSAESGSGSEEEE--------EEEEEEEEEGSTSEESEEEEEEEEEE 64

Query: 317 AE------EGISEQPCP--ADTEVVEDSLRQRKS 342
            E      E  SEQ     ++ E+ ED  R+ ++
Sbjct: 65  EEETGSNSEEASEQSAEEVSEEEMSEDEERENEN 98


>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           2 [Homo sapiens]
          Length = 782

 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 37/109 (33%), Positives = 53/109 (48%), Gaps = 11/109 (10%)

Query: 226 SEQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAE----EEEE 281
           SE+   S E+  AE    +EEE+++  EEE + S  ++ EE+E+  +E+E E     EE 
Sbjct: 272 SERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEA 331

Query: 282 EDNLAAGV-------DEERSEANDQGPPGEDGVTREEVEPEEAEEGISE 323
            +  A  V       DEER   N      E    R+  E EEAEE + E
Sbjct: 332 SEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGE 380



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 31/115 (26%), Positives = 53/115 (46%), Gaps = 3/115 (2%)

Query: 219 PRHLSERSE--QNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEA 276
           PR   ER E    R+  +  + E+ +D   +  D ++ E K S  +    +   G E+E 
Sbjct: 236 PRPPRERFELGDGRKPVKEEKMEE-RDLLSDLQDISDSERKTSSAESSSAESGSGSEEEE 294

Query: 277 EEEEEEDNLAAGVDEERSEANDQGPPGEDGVTREEVEPEEAEEGISEQPCPADTE 331
           EEEEEE+   +  +E   E  ++    E+  +  E   E++ E +SE+    D E
Sbjct: 295 EEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEE 349



 Score = 28.5 bits (62), Expect = 9.4
 Identities = 18/66 (27%), Positives = 29/66 (43%), Gaps = 5/66 (7%)

Query: 227 EQNRRSEEAHRAE-----QLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEEEE 281
           E+ RR E+  +AE        D + ++D   E E +D  ++          ED  E+  E
Sbjct: 19  EKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRGE 78

Query: 282 EDNLAA 287
           ED+  A
Sbjct: 79  EDDSLA 84


>gi|55956788 nucleolin [Homo sapiens]
          Length = 710

 Score = 52.0 bits (123), Expect = 8e-07
 Identities = 32/138 (23%), Positives = 62/138 (44%), Gaps = 37/138 (26%)

Query: 225 RSEQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSL----------------VDDEEEKE 268
           ++ +N + E++   E     E+E+DD +E+E++D +                 DDE++++
Sbjct: 135 KNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDED 194

Query: 269 DLGDEDEAEEEEEED---------------------NLAAGVDEERSEANDQGPPGEDGV 307
           D  D+D+ E++ EE+                     N+A   DEE  + ++     ED  
Sbjct: 195 DEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDE 254

Query: 308 TREEVEPEEAEEGISEQP 325
             ++ + EE EE   E+P
Sbjct: 255 DDDDEDDEEEEEEEEEEP 272



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 26/76 (34%), Positives = 41/76 (53%), Gaps = 3/76 (3%)

Query: 242 QDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEEEEEDNLAAGVDEERSEANDQGP 301
           +D +EE+DD +E+++ D   +D+E+ +D  DE+E EEEEEE    A    ++  A  +  
Sbjct: 234 EDEDEEEDDEDEDDDDD---EDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAA 290

Query: 302 PGEDGVTREEVEPEEA 317
           P       E  EP  A
Sbjct: 291 PEAKKQKVEGTEPTTA 306



 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 31/124 (25%), Positives = 58/124 (46%), Gaps = 31/124 (25%)

Query: 224 ERSEQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDE-------- 275
           E  +++     A +A     A E++DD ++E+++D    D++++ED  +E+         
Sbjct: 163 EDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDED----DDDDEEDDSEEEAMETTPAKG 218

Query: 276 --------------AEEEEEEDNLAAGVDEERSEANDQGPPGEDGVTREEVEPEEAEEGI 321
                         AE+E+EE++     DE+  + +D+    +D    EE E EE EE +
Sbjct: 219 KKAAKVVPVKAKNVAEDEDEEED-----DEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPV 273

Query: 322 SEQP 325
            E P
Sbjct: 274 KEAP 277



 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 25/99 (25%), Positives = 49/99 (49%), Gaps = 17/99 (17%)

Query: 243 DAEEEKDDSNEEENKDS-----------------LVDDEEEKEDLGDEDEAEEEEEEDNL 285
           D ++E+DDS EE  + +                 + +DE+E+ED  DED+ ++E++ED+ 
Sbjct: 198 DDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDD 257

Query: 286 AAGVDEERSEANDQGPPGEDGVTREEVEPEEAEEGISEQ 324
               +EE  E  ++      G  ++E+  ++A     +Q
Sbjct: 258 DEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQ 296



 Score = 30.0 bits (66), Expect = 3.2
 Identities = 18/71 (25%), Positives = 34/71 (47%), Gaps = 4/71 (5%)

Query: 235 AHRAEQLQDAEEEKDDSNEEENKDSLVDD----EEEKEDLGDEDEAEEEEEEDNLAAGVD 290
           A   ++ +D E+E DD +E++  D   DD    EEE+E+   E   + ++E     A  +
Sbjct: 233 AEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPE 292

Query: 291 EERSEANDQGP 301
            ++ +     P
Sbjct: 293 AKKQKVEGTEP 303


>gi|155030232 proline, glutamic acid and leucine rich protein 1
           [Homo sapiens]
          Length = 1130

 Score = 52.0 bits (123), Expect = 8e-07
 Identities = 29/88 (32%), Positives = 47/88 (53%)

Query: 226 SEQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEEEEEDNL 285
           S++    EE    E+ ++ EEE+D   EEE+++   ++EEE+E+  +E+  EEE E +  
Sbjct: 886 SDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEE 945

Query: 286 AAGVDEERSEANDQGPPGEDGVTREEVE 313
               DEE  E  ++    E G    EVE
Sbjct: 946 EEEEDEEEEEELEEVEDLEFGTAGGEVE 973



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 29/87 (33%), Positives = 48/87 (55%), Gaps = 8/87 (9%)

Query: 233 EEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEEEEEDNLAAGVDEE 292
           EE      +  ++EE+++  EEE ++   ++EEE+ED  +E+E EEE  E+      +EE
Sbjct: 875 EEDLTVININSSDEEEEEEEEEEEEEE--EEEEEEEDFEEEEEDEEEYFEE------EEE 926

Query: 293 RSEANDQGPPGEDGVTREEVEPEEAEE 319
             E  ++    E+G   EE E E+ EE
Sbjct: 927 EEEEFEEEFEEEEGELEEEEEEEDEEE 953



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 25/71 (35%), Positives = 41/71 (57%)

Query: 249 DDSNEEENKDSLVDDEEEKEDLGDEDEAEEEEEEDNLAAGVDEERSEANDQGPPGEDGVT 308
           + S+EEE ++   ++EEE+E+  +ED  EEEE+E+      +EE  E  ++    E  + 
Sbjct: 884 NSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELE 943

Query: 309 REEVEPEEAEE 319
            EE E +E EE
Sbjct: 944 EEEEEEDEEEE 954



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 39/122 (31%), Positives = 61/122 (50%), Gaps = 18/122 (14%)

Query: 224  ERSEQNRRSEEAHRAEQLQDAEEEKDDSNEE-ENKDSLVDDEEEKEDLGDEDEAEEEEEE 282
            E  E++   EE    E  ++ EEE+++  EE E ++  +++EEE+ED   E+E EE EE 
Sbjct: 904  EEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEED---EEEEEELEEV 960

Query: 283  DNL----AAGVDEERSEANDQGPPG---EDGVTREEVEPE-------EAEEGISEQPCPA 328
            ++L    A G  EE +      PP     +   + + EPE       E EE  +E+   A
Sbjct: 961  EDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGA 1020

Query: 329  DT 330
            DT
Sbjct: 1021 DT 1022



 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 28/77 (36%), Positives = 42/77 (54%), Gaps = 4/77 (5%)

Query: 262 DDEEEKEDLGDEDEAEEEEEEDNLAAGVDEER---SEANDQGPPGEDGVTREEVEPEEAE 318
           D+EEE+E+  +E+E EEEEEE++     ++E     E  ++    E+    EE E EE E
Sbjct: 887 DEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEE 946

Query: 319 EGISEQPCPADTEVVED 335
           E   E+    + E VED
Sbjct: 947 EEEDEEE-EEELEEVED 962



 Score = 30.0 bits (66), Expect = 3.2
 Identities = 16/58 (27%), Positives = 28/58 (48%)

Query: 245  EEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEEEEEDNLAAGVDEERSEANDQGPP 302
            EEE +D +++         EEE E   + +  +E+E++D  A   D      +D+ PP
Sbjct: 1066 EEETEDGSDKVQPPPETPAEEEMETETEAEALQEKEQDDTAAMLADFIDCPPDDEKPP 1123


>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
          Length = 709

 Score = 52.0 bits (123), Expect = 8e-07
 Identities = 31/84 (36%), Positives = 48/84 (57%), Gaps = 6/84 (7%)

Query: 223 SERSEQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEEE-- 280
           S+    N  +EE    E +++ EE ++D+ E+E  D   ++EEE+E+  +E+E EEEE  
Sbjct: 191 SDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEY 250

Query: 281 ---EEDNLAAGVD-EERSEANDQG 300
              E D    G D + RSEA+D G
Sbjct: 251 EQDERDQKEEGNDYDTRSEASDSG 274



 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 28/95 (29%), Positives = 47/95 (49%), Gaps = 2/95 (2%)

Query: 224 ERSEQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEEEEED 283
           E        E+ +  E  ++  EE  + +EE  +D+  +++EE ++ G+E+E EEEEEE+
Sbjct: 184 ETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDA--EEDEEVDEDGEEEEEEEEEEEE 241

Query: 284 NLAAGVDEERSEANDQGPPGEDGVTREEVEPEEAE 318
                 +E   +  DQ   G D  TR E     +E
Sbjct: 242 EEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSE 276



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 38/138 (27%), Positives = 64/138 (46%), Gaps = 15/138 (10%)

Query: 211 SECFYVPLPRHLSERSEQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDL 270
           SE   + + R  S  S+ ++  EE +  E   D E     S++E+  ++  ++E  +ED+
Sbjct: 152 SERIGLEVDRRASRSSQSSK--EEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDV 209

Query: 271 GDEDEAEEEEEEDNLAAGVDEERSEANDQGPPGEDGVTREEVEPEEAEEGISEQPCPADT 330
            +++E EE+ EED     VDE+          GE+    EE E EE EE   E       
Sbjct: 210 EEDEEVEEDAEEDE---EVDED----------GEEEEEEEEEEEEEEEEEEEEYEQDERD 256

Query: 331 EVVEDSLRQRKSQHADKG 348
           +  E +    +S+ +D G
Sbjct: 257 QKEEGNDYDTRSEASDSG 274



 Score = 36.6 bits (83), Expect = 0.034
 Identities = 19/87 (21%), Positives = 39/87 (44%)

Query: 224 ERSEQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEEEEED 283
           E  E     EE     + ++ EEE+++  EEE ++    DE ++++ G++ +   E  + 
Sbjct: 214 EVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDS 273

Query: 284 NLAAGVDEERSEANDQGPPGEDGVTRE 310
              +    + S  +  G  G D   +E
Sbjct: 274 GSESVSFTDGSVRSGSGTDGSDEKKKE 300



 Score = 35.8 bits (81), Expect = 0.059
 Identities = 24/101 (23%), Positives = 50/101 (49%), Gaps = 7/101 (6%)

Query: 222 LSERSEQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEEEE 281
           + E +E++   +E    E+ ++ EEE+++  EEE  +   D+ ++KE+  D D   E  +
Sbjct: 215 VEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQ--DERDQKEEGNDYDTRSEASD 272

Query: 282 EDNLAAGVDEERSEANDQGPPGEDGVTREEVEPEEAEEGIS 322
             + +       ++ + +   G DG   ++ E + A  GIS
Sbjct: 273 SGSESVSF----TDGSVRSGSGTDGSDEKKKERKRA-RGIS 308


>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
          Length = 727

 Score = 52.0 bits (123), Expect = 8e-07
 Identities = 31/84 (36%), Positives = 48/84 (57%), Gaps = 6/84 (7%)

Query: 223 SERSEQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEEE-- 280
           S+    N  +EE    E +++ EE ++D+ E+E  D   ++EEE+E+  +E+E EEEE  
Sbjct: 191 SDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEY 250

Query: 281 ---EEDNLAAGVD-EERSEANDQG 300
              E D    G D + RSEA+D G
Sbjct: 251 EQDERDQKEEGNDYDTRSEASDSG 274



 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 28/95 (29%), Positives = 47/95 (49%), Gaps = 2/95 (2%)

Query: 224 ERSEQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEEEEED 283
           E        E+ +  E  ++  EE  + +EE  +D+  +++EE ++ G+E+E EEEEEE+
Sbjct: 184 ETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDA--EEDEEVDEDGEEEEEEEEEEEE 241

Query: 284 NLAAGVDEERSEANDQGPPGEDGVTREEVEPEEAE 318
                 +E   +  DQ   G D  TR E     +E
Sbjct: 242 EEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSE 276



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 38/138 (27%), Positives = 64/138 (46%), Gaps = 15/138 (10%)

Query: 211 SECFYVPLPRHLSERSEQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDL 270
           SE   + + R  S  S+ ++  EE +  E   D E     S++E+  ++  ++E  +ED+
Sbjct: 152 SERIGLEVDRRASRSSQSSK--EEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDV 209

Query: 271 GDEDEAEEEEEEDNLAAGVDEERSEANDQGPPGEDGVTREEVEPEEAEEGISEQPCPADT 330
            +++E EE+ EED     VDE+          GE+    EE E EE EE   E       
Sbjct: 210 EEDEEVEEDAEEDE---EVDED----------GEEEEEEEEEEEEEEEEEEEEYEQDERD 256

Query: 331 EVVEDSLRQRKSQHADKG 348
           +  E +    +S+ +D G
Sbjct: 257 QKEEGNDYDTRSEASDSG 274



 Score = 36.6 bits (83), Expect = 0.034
 Identities = 19/87 (21%), Positives = 39/87 (44%)

Query: 224 ERSEQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEEEEED 283
           E  E     EE     + ++ EEE+++  EEE ++    DE ++++ G++ +   E  + 
Sbjct: 214 EVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDS 273

Query: 284 NLAAGVDEERSEANDQGPPGEDGVTRE 310
              +    + S  +  G  G D   +E
Sbjct: 274 GSESVSFTDGSVRSGSGTDGSDEKKKE 300



 Score = 35.8 bits (81), Expect = 0.059
 Identities = 24/101 (23%), Positives = 50/101 (49%), Gaps = 7/101 (6%)

Query: 222 LSERSEQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEEEE 281
           + E +E++   +E    E+ ++ EEE+++  EEE  +   D+ ++KE+  D D   E  +
Sbjct: 215 VEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQ--DERDQKEEGNDYDTRSEASD 272

Query: 282 EDNLAAGVDEERSEANDQGPPGEDGVTREEVEPEEAEEGIS 322
             + +       ++ + +   G DG   ++ E + A  GIS
Sbjct: 273 SGSESVSF----TDGSVRSGSGTDGSDEKKKERKRA-RGIS 308


>gi|21361639 DIPB protein [Homo sapiens]
          Length = 344

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 35/105 (33%), Positives = 53/105 (50%), Gaps = 17/105 (16%)

Query: 223 SERSEQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEEEEE 282
           SE  E++   EE+   E+ +  EE +D+S+EE  +DS    EEE      EDE E E EE
Sbjct: 93  SEAGEESESEEESESEEESETEEESEDESDEESEEDS----EEEM-----EDEQESEAEE 143

Query: 283 DNLAAGVDEERSEANDQGPPGEDGVTREEVEPEEAEEGISEQPCP 327
           DN      +E  E+  +G    +     E+E E   E ++++ CP
Sbjct: 144 DN------QEEGESEAEGETEAESEFDPEIEME--AERVAKRKCP 180



 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 36/118 (30%), Positives = 57/118 (48%), Gaps = 13/118 (11%)

Query: 233 EEAH-RAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEEEEEDNLAAGVDE 291
           EEA  + EQ ++ E E  + +E E +    ++ E +E+   EDE++EE EED+     DE
Sbjct: 79  EEAEVKVEQEREIESEAGEESESEEESESEEESETEEE--SEDESDEESEEDSEEEMEDE 136

Query: 292 ERSEANDQGPPGEDGVTREEVEPEEAEEGISEQPCPADTEVVEDSLRQRKSQHADKGL 349
           + SEA +            + E E   EG +E     D E+  ++ R  K +  D GL
Sbjct: 137 QESEAEED----------NQEEGESEAEGETEAESEFDPEIEMEAERVAKRKCPDHGL 184


>gi|42476169 Paf1, RNA polymerase II associated factor, homolog
           [Homo sapiens]
          Length = 531

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 33/121 (27%), Positives = 63/121 (52%), Gaps = 3/121 (2%)

Query: 224 ERSEQNRRSEEAHRAE-QLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEEEEE 282
           + +E+   ++EA +A+ +  + EEE+++  E E K++   DEE+++    E E  E+E  
Sbjct: 355 DMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHS 414

Query: 283 DNLAAGVDEERSEANDQGPPGEDGVTREEVEPEEAEEGISEQPCPADTEVVEDSLRQRKS 342
            + +   + +R EA+D+   GED  + +E      +E I      AD+E   DS  + + 
Sbjct: 415 GSESEREEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGS--DADSEDDADSDDEDRG 472

Query: 343 Q 343
           Q
Sbjct: 473 Q 473



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 29/128 (22%), Positives = 55/128 (42%), Gaps = 1/128 (0%)

Query: 218 LPRHLSERSEQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAE 277
           L  H  E  E+     E   A    D E+EK  S+E+E  +      E + + GD DEA 
Sbjct: 371 LENHEPEEEEEEEMETEEKEAGG-SDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEAS 429

Query: 278 EEEEEDNLAAGVDEERSEANDQGPPGEDGVTREEVEPEEAEEGISEQPCPADTEVVEDSL 337
           ++       +  DE R+  + +   G D  + ++ + ++ + G ++     D++   +  
Sbjct: 430 DKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDNDSDSGSNGG 489

Query: 338 RQRKSQHA 345
            QR   H+
Sbjct: 490 GQRSRSHS 497



 Score = 34.3 bits (77), Expect = 0.17
 Identities = 29/108 (26%), Positives = 49/108 (45%), Gaps = 10/108 (9%)

Query: 236 HRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEEEEEDNLAAGVDEERSE 295
           HR    ++ E ++    + EN +   ++EEE E   +E EA   +EE    +  ++E SE
Sbjct: 353 HRDMNEKELEAQEARKAQLENHEPEEEEEEEMET--EEKEAGGSDEEQEKGSSSEKEGSE 410

Query: 296 ANDQGPPGEDGVTREEVEPEEAEEGISEQPCPADTEVVEDSLRQRKSQ 343
               G   E    REE + +EA    S++    + E  ED  R  + +
Sbjct: 411 DEHSGSESE----REEGDRDEA----SDKSGSGEDESSEDEARAARDK 450


>gi|75677335 digestive-organ expansion factor homolog [Homo sapiens]
          Length = 756

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 34/111 (30%), Positives = 51/111 (45%), Gaps = 13/111 (11%)

Query: 244 AEEEKDDSNEEENKDSLVDDEEEKEDLGDED-------EAEEEEEEDNLAAGVDEERSEA 296
           +EEE++D  EEE +DS+VDD E  ++ G  D        AE  E  +N+A   D E  E 
Sbjct: 83  SEEEEEDEEEEEEEDSIVDDAEMNDEDGGSDVSVEEEMAAESTESPENVALSADPEGKED 142

Query: 297 NDQGPPGEDGVTREEVEPEEAEEGISEQPCPADTEVVEDSLRQRKSQHADK 347
            ++ PPG       +  PEE  +   E     +T  +E+      S  A +
Sbjct: 143 GEE-PPG-----TSQTSPEEFTDAKHESLFSLETNFLEEESGDNSSLKASQ 187



 Score = 33.5 bits (75), Expect = 0.29
 Identities = 38/134 (28%), Positives = 59/134 (44%), Gaps = 31/134 (23%)

Query: 220 RHLSERSEQNRRSEEAHRAE------QLQDAEEEKDDSNEEENKDSLVD----------- 262
           +HL +  E++   +   R E      QL ++ +  D  ++ E++   V            
Sbjct: 22  KHLRDFGEEHPFYDRVSRKEAKPQICQLSESSDSSDSESDSESEPQQVSGYHRLLATLKN 81

Query: 263 -DEEEKEDLGDEDEAEEEEEEDNLAAGVDEERSEANDQGPPGEDGVTREEVEPEEAEEGI 321
             EEE+ED  +E    EEEEED++   VD+  +E ND+   G   V+ EE    E+ E  
Sbjct: 82  VSEEEEED--EE----EEEEEDSI---VDD--AEMNDE--DGGSDVSVEEEMAAESTESP 128

Query: 322 SEQPCPADTEVVED 335
                 AD E  ED
Sbjct: 129 ENVALSADPEGKED 142


>gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 family,
           member E isoform 1 [Homo sapiens]
          Length = 268

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 34/122 (27%), Positives = 62/122 (50%), Gaps = 9/122 (7%)

Query: 229 NRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEEEEEDNLAAG 288
           ++   EA  +E+  D + ++DD  EEEN+    +  EE+E+  +E++ +E+E+ED   + 
Sbjct: 149 DQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSE 208

Query: 289 VDEERSEANDQGPPGEDGVTREEVEPEEAEEGISEQPCPADTEVVEDSLR--QRKSQHAD 346
           + E   E       G   + +EE++ EE ++   E+    + E  E  LR  +RK    D
Sbjct: 209 LGEGEEEV------GLSYLMKEEIQDEEDDDDYVEEG-EEEEEEEEGGLRGEKRKRDAED 261

Query: 347 KG 348
            G
Sbjct: 262 DG 263



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 27/111 (24%), Positives = 52/111 (46%), Gaps = 7/111 (6%)

Query: 227 EQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDEDEAEEEEEEDNLA 286
           E N   +     ++  D ++E+++ NE    +   ++EEE+E+  ++++ +E+E    L 
Sbjct: 151 EDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELG 210

Query: 287 AGVDE------ERSEANDQGPPGEDGVTREEVEPEEAEEGISEQPCPADTE 331
            G +E       + E  D+    +D V   E E EE E G+  +    D E
Sbjct: 211 EGEEEVGLSYLMKEEIQDE-EDDDDYVEEGEEEEEEEEGGLRGEKRKRDAE 260



 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 26/97 (26%), Positives = 46/97 (47%), Gaps = 15/97 (15%)

Query: 224 ERSEQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEE--------KEDLGDE-- 273
           E  E      E +  E+ ++ EE++D+  +E+   S + + EE        KE++ DE  
Sbjct: 172 EEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEED 231

Query: 274 -----DEAEEEEEEDNLAAGVDEERSEANDQGPPGED 305
                +E EEEEEE+      ++ + +A D G   +D
Sbjct: 232 DDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD 268


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.132    0.397 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,462,992
Number of Sequences: 37866
Number of extensions: 831860
Number of successful extensions: 29513
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 751
Number of HSP's successfully gapped in prelim test: 673
Number of HSP's that attempted gapping in prelim test: 7749
Number of HSP's gapped (non-prelim): 9063
length of query: 349
length of database: 18,247,518
effective HSP length: 103
effective length of query: 246
effective length of database: 14,347,320
effective search space: 3529440720
effective search space used: 3529440720
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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