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Search of human proteins with 40068505
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40068505 seipin isoform 2 [Homo sapiens]
(398 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|171906569 seipin isoform 1 [Homo sapiens] 803 0.0
gi|195230753 seipin isoform 1 [Homo sapiens] 803 0.0
gi|40068505 seipin isoform 2 [Homo sapiens] 803 0.0
gi|21328446 hormone-sensitive lipase [Homo sapiens] 42 0.001
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 41 0.002
gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens] 41 0.002
gi|42476169 Paf1, RNA polymerase II associated factor, homolog [... 41 0.002
gi|119709834 castor homolog 1, zinc finger isoform a [Homo sapiens] 39 0.011
gi|156104891 general transcription factor IIF, polypeptide 1, 74... 38 0.014
gi|4826694 integral membrane protein DGCR2 [Homo sapiens] 37 0.024
gi|194097398 protein tyrosine phosphatase, receptor type, G prec... 37 0.024
gi|33286446 opioid growth factor receptor [Homo sapiens] 37 0.031
gi|40254947 thioredoxin-related transmembrane protein 4 [Homo sa... 37 0.031
gi|115511012 coiled-coil domain containing 136 [Homo sapiens] 37 0.041
gi|34482047 adaptor-related protein complex 3, beta 2 subunit [H... 36 0.053
gi|218505694 potassium channel tetramerisation domain containing... 36 0.053
gi|58331268 excision repair protein ERCC6-like [Homo sapiens] 36 0.053
gi|4506411 Ran GTPase activating protein 1 [Homo sapiens] 36 0.053
gi|17975763 myelin transcription factor 1 [Homo sapiens] 36 0.070
gi|57634514 SPANX-N2 protein [Homo sapiens] 36 0.070
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 36 0.070
gi|153945734 teashirt zinc finger homeobox 2 [Homo sapiens] 36 0.070
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 35 0.091
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 35 0.091
gi|169207217 PREDICTED: zinc finger homeobox 2 [Homo sapiens] 35 0.12
gi|239752280 PREDICTED: similar to family with sequence similari... 35 0.12
gi|169207592 PREDICTED: zinc finger homeobox 2 [Homo sapiens] 35 0.12
gi|169207014 PREDICTED: zinc finger homeobox 2 [Homo sapiens] 35 0.12
gi|5031579 A-kinase anchor protein 8 [Homo sapiens] 35 0.12
gi|210032463 family with sequence similarity 48, member B2 [Homo... 35 0.12
>gi|171906569 seipin isoform 1 [Homo sapiens]
Length = 462
Score = 803 bits (2074), Expect = 0.0
Identities = 398/398 (100%), Positives = 398/398 (100%)
Query: 1 MVNDPPVPALLWAQEVGQVLAGRARRLLLQFGVLFCTILLLLWVSVFLYGSFYYSYMPTV 60
MVNDPPVPALLWAQEVGQVLAGRARRLLLQFGVLFCTILLLLWVSVFLYGSFYYSYMPTV
Sbjct: 65 MVNDPPVPALLWAQEVGQVLAGRARRLLLQFGVLFCTILLLLWVSVFLYGSFYYSYMPTV 124
Query: 61 SHLSPVHFYYRTDCDSSTTSLCSFPVANVSLTKGGRDRVLMYGQPYRVTLELELPESPVN 120
SHLSPVHFYYRTDCDSSTTSLCSFPVANVSLTKGGRDRVLMYGQPYRVTLELELPESPVN
Sbjct: 125 SHLSPVHFYYRTDCDSSTTSLCSFPVANVSLTKGGRDRVLMYGQPYRVTLELELPESPVN 184
Query: 121 QDLGMFLVTISCYTRGGRIISTSSRSVMLHYRSDLLQMLDTLVFSSLLLFGFAEQKQLLE 180
QDLGMFLVTISCYTRGGRIISTSSRSVMLHYRSDLLQMLDTLVFSSLLLFGFAEQKQLLE
Sbjct: 185 QDLGMFLVTISCYTRGGRIISTSSRSVMLHYRSDLLQMLDTLVFSSLLLFGFAEQKQLLE 244
Query: 181 VELYADYRENSYVPTTGAIIEIHSKRIQLYGAYLRIHAHFTGLRYLLYNFPMTCAFIGVA 240
VELYADYRENSYVPTTGAIIEIHSKRIQLYGAYLRIHAHFTGLRYLLYNFPMTCAFIGVA
Sbjct: 245 VELYADYRENSYVPTTGAIIEIHSKRIQLYGAYLRIHAHFTGLRYLLYNFPMTCAFIGVA 304
Query: 241 SNFTFLSVIVLFSYMQWVWGGIWPRHRFSLQVNIRKRDNSRKEVQRRISAHQPGPEGQEE 300
SNFTFLSVIVLFSYMQWVWGGIWPRHRFSLQVNIRKRDNSRKEVQRRISAHQPGPEGQEE
Sbjct: 305 SNFTFLSVIVLFSYMQWVWGGIWPRHRFSLQVNIRKRDNSRKEVQRRISAHQPGPEGQEE 364
Query: 301 STPQSDVTEDGESPEDPSGTEGQLSEEEKPDQQPLSGEEELEPEASDGSGSWEDAALLTE 360
STPQSDVTEDGESPEDPSGTEGQLSEEEKPDQQPLSGEEELEPEASDGSGSWEDAALLTE
Sbjct: 365 STPQSDVTEDGESPEDPSGTEGQLSEEEKPDQQPLSGEEELEPEASDGSGSWEDAALLTE 424
Query: 361 ANLPAPAPASASAPVLETLGSSEPAGGALRQRPTCSSS 398
ANLPAPAPASASAPVLETLGSSEPAGGALRQRPTCSSS
Sbjct: 425 ANLPAPAPASASAPVLETLGSSEPAGGALRQRPTCSSS 462
>gi|195230753 seipin isoform 1 [Homo sapiens]
Length = 462
Score = 803 bits (2074), Expect = 0.0
Identities = 398/398 (100%), Positives = 398/398 (100%)
Query: 1 MVNDPPVPALLWAQEVGQVLAGRARRLLLQFGVLFCTILLLLWVSVFLYGSFYYSYMPTV 60
MVNDPPVPALLWAQEVGQVLAGRARRLLLQFGVLFCTILLLLWVSVFLYGSFYYSYMPTV
Sbjct: 65 MVNDPPVPALLWAQEVGQVLAGRARRLLLQFGVLFCTILLLLWVSVFLYGSFYYSYMPTV 124
Query: 61 SHLSPVHFYYRTDCDSSTTSLCSFPVANVSLTKGGRDRVLMYGQPYRVTLELELPESPVN 120
SHLSPVHFYYRTDCDSSTTSLCSFPVANVSLTKGGRDRVLMYGQPYRVTLELELPESPVN
Sbjct: 125 SHLSPVHFYYRTDCDSSTTSLCSFPVANVSLTKGGRDRVLMYGQPYRVTLELELPESPVN 184
Query: 121 QDLGMFLVTISCYTRGGRIISTSSRSVMLHYRSDLLQMLDTLVFSSLLLFGFAEQKQLLE 180
QDLGMFLVTISCYTRGGRIISTSSRSVMLHYRSDLLQMLDTLVFSSLLLFGFAEQKQLLE
Sbjct: 185 QDLGMFLVTISCYTRGGRIISTSSRSVMLHYRSDLLQMLDTLVFSSLLLFGFAEQKQLLE 244
Query: 181 VELYADYRENSYVPTTGAIIEIHSKRIQLYGAYLRIHAHFTGLRYLLYNFPMTCAFIGVA 240
VELYADYRENSYVPTTGAIIEIHSKRIQLYGAYLRIHAHFTGLRYLLYNFPMTCAFIGVA
Sbjct: 245 VELYADYRENSYVPTTGAIIEIHSKRIQLYGAYLRIHAHFTGLRYLLYNFPMTCAFIGVA 304
Query: 241 SNFTFLSVIVLFSYMQWVWGGIWPRHRFSLQVNIRKRDNSRKEVQRRISAHQPGPEGQEE 300
SNFTFLSVIVLFSYMQWVWGGIWPRHRFSLQVNIRKRDNSRKEVQRRISAHQPGPEGQEE
Sbjct: 305 SNFTFLSVIVLFSYMQWVWGGIWPRHRFSLQVNIRKRDNSRKEVQRRISAHQPGPEGQEE 364
Query: 301 STPQSDVTEDGESPEDPSGTEGQLSEEEKPDQQPLSGEEELEPEASDGSGSWEDAALLTE 360
STPQSDVTEDGESPEDPSGTEGQLSEEEKPDQQPLSGEEELEPEASDGSGSWEDAALLTE
Sbjct: 365 STPQSDVTEDGESPEDPSGTEGQLSEEEKPDQQPLSGEEELEPEASDGSGSWEDAALLTE 424
Query: 361 ANLPAPAPASASAPVLETLGSSEPAGGALRQRPTCSSS 398
ANLPAPAPASASAPVLETLGSSEPAGGALRQRPTCSSS
Sbjct: 425 ANLPAPAPASASAPVLETLGSSEPAGGALRQRPTCSSS 462
>gi|40068505 seipin isoform 2 [Homo sapiens]
Length = 398
Score = 803 bits (2074), Expect = 0.0
Identities = 398/398 (100%), Positives = 398/398 (100%)
Query: 1 MVNDPPVPALLWAQEVGQVLAGRARRLLLQFGVLFCTILLLLWVSVFLYGSFYYSYMPTV 60
MVNDPPVPALLWAQEVGQVLAGRARRLLLQFGVLFCTILLLLWVSVFLYGSFYYSYMPTV
Sbjct: 1 MVNDPPVPALLWAQEVGQVLAGRARRLLLQFGVLFCTILLLLWVSVFLYGSFYYSYMPTV 60
Query: 61 SHLSPVHFYYRTDCDSSTTSLCSFPVANVSLTKGGRDRVLMYGQPYRVTLELELPESPVN 120
SHLSPVHFYYRTDCDSSTTSLCSFPVANVSLTKGGRDRVLMYGQPYRVTLELELPESPVN
Sbjct: 61 SHLSPVHFYYRTDCDSSTTSLCSFPVANVSLTKGGRDRVLMYGQPYRVTLELELPESPVN 120
Query: 121 QDLGMFLVTISCYTRGGRIISTSSRSVMLHYRSDLLQMLDTLVFSSLLLFGFAEQKQLLE 180
QDLGMFLVTISCYTRGGRIISTSSRSVMLHYRSDLLQMLDTLVFSSLLLFGFAEQKQLLE
Sbjct: 121 QDLGMFLVTISCYTRGGRIISTSSRSVMLHYRSDLLQMLDTLVFSSLLLFGFAEQKQLLE 180
Query: 181 VELYADYRENSYVPTTGAIIEIHSKRIQLYGAYLRIHAHFTGLRYLLYNFPMTCAFIGVA 240
VELYADYRENSYVPTTGAIIEIHSKRIQLYGAYLRIHAHFTGLRYLLYNFPMTCAFIGVA
Sbjct: 181 VELYADYRENSYVPTTGAIIEIHSKRIQLYGAYLRIHAHFTGLRYLLYNFPMTCAFIGVA 240
Query: 241 SNFTFLSVIVLFSYMQWVWGGIWPRHRFSLQVNIRKRDNSRKEVQRRISAHQPGPEGQEE 300
SNFTFLSVIVLFSYMQWVWGGIWPRHRFSLQVNIRKRDNSRKEVQRRISAHQPGPEGQEE
Sbjct: 241 SNFTFLSVIVLFSYMQWVWGGIWPRHRFSLQVNIRKRDNSRKEVQRRISAHQPGPEGQEE 300
Query: 301 STPQSDVTEDGESPEDPSGTEGQLSEEEKPDQQPLSGEEELEPEASDGSGSWEDAALLTE 360
STPQSDVTEDGESPEDPSGTEGQLSEEEKPDQQPLSGEEELEPEASDGSGSWEDAALLTE
Sbjct: 301 STPQSDVTEDGESPEDPSGTEGQLSEEEKPDQQPLSGEEELEPEASDGSGSWEDAALLTE 360
Query: 361 ANLPAPAPASASAPVLETLGSSEPAGGALRQRPTCSSS 398
ANLPAPAPASASAPVLETLGSSEPAGGALRQRPTCSSS
Sbjct: 361 ANLPAPAPASASAPVLETLGSSEPAGGALRQRPTCSSS 398
>gi|21328446 hormone-sensitive lipase [Homo sapiens]
Length = 1076
Score = 42.0 bits (97), Expect = 0.001
Identities = 37/134 (27%), Positives = 59/134 (44%), Gaps = 20/134 (14%)
Query: 273 NIRKRDNSRKEVQRRISAHQPGPEGQEESTPQSDVTEDGESPEDPSGTEGQLSEEEKPDQ 332
++ + D + QR I+ +PGPE + P+S + + + P+ + L+++E P Q
Sbjct: 7 SVSRSDWQPEPHQRPITPLEPGPEKTPIAQPESKTLQGSNTQQKPASNQRPLTQQETPAQ 66
Query: 333 QPLSGEEELEPEASDGSGSWEDAALLTEANLPAPAP------------ASASAPVL--ET 378
E + EP A S S E+ L + P +P AS P L E+
Sbjct: 67 H--DAESQKEPRAQQKSASQEE-FLAPQKPAPQQSPYIQRVLLTQQEAASQQGPGLGKES 123
Query: 379 LGSSEPAGGALRQR 392
+ EP ALRQR
Sbjct: 124 ITQQEP---ALRQR 134
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 41.2 bits (95), Expect = 0.002
Identities = 33/108 (30%), Positives = 46/108 (42%), Gaps = 5/108 (4%)
Query: 278 DNSRKEVQRRISAHQPGPEG-QEESTPQSDVTEDGESPEDPSGTEGQLSEEEKPDQQPLS 336
+ ++E + + G EG QEE +V E E E L EE P++ +
Sbjct: 1347 EGQQEEEAQLEEIEETGGEGLQEEGVQLEEVKEGPEGGLQGEALEEGLKEEGLPEEGSVH 1406
Query: 337 GEEELEPEASDGSGSWEDAALLTEANLPAPAPASASAPVLETLGSSEP 384
G+E E + DG GS ED + E ASASA G+ EP
Sbjct: 1407 GQELSEASSPDGKGSQEDDPVQEE----EAGRASASAEPCPAEGTEEP 1450
Score = 40.4 bits (93), Expect = 0.003
Identities = 31/98 (31%), Positives = 44/98 (44%), Gaps = 10/98 (10%)
Query: 295 PEGQEESTPQSDVTEDGESPEDPSGTEGQLSEEEKPDQQPLSGEEELEPEASD---GSGS 351
PE + E+ P+S+ E E+ D EG+ ++ E D + E E +PE+ D
Sbjct: 1838 PEAEGEAQPESEGVEAPEAEGDAQEAEGE-AQPESEDVEAPEAEGEAQPESEDVETPEAE 1896
Query: 352 WE-----DAALLTEANLPAPAPASASAPVLETLGSSEP 384
WE + A EA A P + S LET G EP
Sbjct: 1897 WEVQPESEGAEAPEAEKEA-QPETESVEALETEGEDEP 1933
Score = 35.8 bits (81), Expect = 0.070
Identities = 30/99 (30%), Positives = 44/99 (44%), Gaps = 21/99 (21%)
Query: 295 PEGQEESTPQSDVTEDGESPEDPSGTEGQLSEEEKPDQQPLSGEEELEPEASDGSGSWED 354
PE +EE+ P+ E E+PE EG+ E + + Q GE++ P+ S G G E+
Sbjct: 2215 PEAEEEAQPE---PEGVETPE----AEGEAQPESEGETQ---GEKKGSPQVSLGDGQSEE 2264
Query: 355 AALLTEANLPAPAPASASAPVLETLGSSEPAGGALRQRP 393
A +E++ P P P P G QRP
Sbjct: 2265 A---SESSSPVPEDRPTPPP--------SPGGDTPHQRP 2292
Score = 34.7 bits (78), Expect = 0.16
Identities = 33/98 (33%), Positives = 41/98 (41%), Gaps = 11/98 (11%)
Query: 295 PEGQEESTPQSDVTE----DGESPEDPSGTEGQLSEEEKPDQQPLSGEE--ELEPEASDG 348
PE + E+ P+S+ E +GE+ + G E Q +EEE Q L G E E E EA
Sbjct: 2135 PEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEA--QPELEGVEAPEAEGEAQPE 2192
Query: 349 SGSWEDAALLTEANLPAPAPASASAPVLETLGSSEPAG 386
S E EA P AP E EP G
Sbjct: 2193 SEGIEAPEAEGEAQ---PELEGVEAPEAEEEAQPEPEG 2227
Score = 32.3 bits (72), Expect = 0.77
Identities = 29/94 (30%), Positives = 37/94 (39%), Gaps = 10/94 (10%)
Query: 295 PEGQEESTPQSDVTEDGESPE-----DPSGTEGQLSEEEKPDQQPLSGEEELEPEASDGS 349
PE + E+ P+S ED E+PE P + E EK Q E LE E D
Sbjct: 1877 PEAEGEAQPES---EDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEP 1933
Query: 350 GSWEDAALLTEANLPAPAPASASAPVLETLGSSE 383
S + A EA A + P E + S E
Sbjct: 1934 ES--EGAEAQEAEEAAQEAEGQTQPESEVIESQE 1965
Score = 31.6 bits (70), Expect = 1.3
Identities = 26/98 (26%), Positives = 45/98 (45%), Gaps = 9/98 (9%)
Query: 295 PEGQEESTPQSDVTE----DGESPEDPSGTEGQLSE-EEKPDQQPL---SGEEELEPEAS 346
PE + E+ P+S+ E +GE+ + G E Q +E E +P+ + + EEE +PE
Sbjct: 2119 PETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELE 2178
Query: 347 DGSGSWEDAALLTEA-NLPAPAPASASAPVLETLGSSE 383
+ E+ + AP + P LE + + E
Sbjct: 2179 GVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPE 2216
Score = 30.0 bits (66), Expect = 3.8
Identities = 17/62 (27%), Positives = 33/62 (53%), Gaps = 1/62 (1%)
Query: 295 PEGQEESTPQSDVTEDGESP-EDPSGTEGQLSEEEKPDQQPLSGEEELEPEASDGSGSWE 353
PE ++E+ P+++ E E+ ED +EG ++E + Q G+ + E E + + E
Sbjct: 1909 PEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEE 1968
Query: 354 DA 355
+A
Sbjct: 1969 EA 1970
Score = 30.0 bits (66), Expect = 3.8
Identities = 27/105 (25%), Positives = 43/105 (40%), Gaps = 13/105 (12%)
Query: 296 EGQEESTPQSDVTE-----DGESPEDPSG----TEGQLSEE----EKPDQQPLSGEEELE 342
E +EE+ P+SD E +GE ++ G TEG E E P+ + + E E E
Sbjct: 2011 EAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGE 2070
Query: 343 PEASDGSGSWEDAALLTEANLPAPAPASASAPVLETLGSSEPAGG 387
+ ++G E + + P S E G ++ A G
Sbjct: 2071 VQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEG 2115
Score = 29.6 bits (65), Expect = 5.0
Identities = 20/69 (28%), Positives = 31/69 (44%), Gaps = 8/69 (11%)
Query: 300 ESTPQSDVTEDGESPEDPSGTEGQLSEEEKPDQQPLSGEEELEPEA--------SDGSGS 351
E ++ V E+ + E GTEG+ +EE + EE L+ E ++G G
Sbjct: 1290 EQLAENTVQEEVQLEETKEGTEGEGLQEEAVQLEETKTEEGLQEEGVQLEETKETEGEGQ 1349
Query: 352 WEDAALLTE 360
E+ A L E
Sbjct: 1350 QEEEAQLEE 1358
Score = 29.3 bits (64), Expect = 6.5
Identities = 17/52 (32%), Positives = 25/52 (48%), Gaps = 1/52 (1%)
Query: 296 EGQEESTPQSDVTEDGESPEDPSGTEGQLSEEEKPDQQPLSGEEELEPEASD 347
E + E P+S+ E E+ E EGQ E + + EEE +PE+ D
Sbjct: 1926 ETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQ-EAEEEAQPESED 1976
>gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens]
Length = 4374
Score = 40.8 bits (94), Expect = 0.002
Identities = 23/70 (32%), Positives = 34/70 (48%)
Query: 280 SRKEVQRRISAHQPGPEGQEESTPQSDVTEDGESPEDPSGTEGQLSEEEKPDQQPLSGEE 339
S + R S + PE +EE T + D + E +D E + E+E+ DQ+ GEE
Sbjct: 2394 STLQANREDSMNILDPEDEEEHTQEEDSSGSNEDEDDSQDEEEEEEEDEEDDQEDDEGEE 2453
Query: 340 ELEPEASDGS 349
E + DGS
Sbjct: 2454 GDEDDDDDGS 2463
>gi|42476169 Paf1, RNA polymerase II associated factor, homolog
[Homo sapiens]
Length = 531
Score = 40.8 bits (94), Expect = 0.002
Identities = 31/96 (32%), Positives = 47/96 (48%), Gaps = 10/96 (10%)
Query: 274 IRKRDNSRKEVQ----RRISAHQPGPEGQEESTPQSDVTEDGESPEDPSGTEGQLSEEEK 329
++ RD + KE++ R+ PE +EE +++ E G S E+ +G SE+E
Sbjct: 351 VKHRDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQE--KGSSSEKEG 408
Query: 330 PDQQPLSGEEELEP----EASDGSGSWEDAALLTEA 361
+ + E E E EASD SGS ED + EA
Sbjct: 409 SEDEHSGSESEREEGDRDEASDKSGSGEDESSEDEA 444
>gi|119709834 castor homolog 1, zinc finger isoform a [Homo sapiens]
Length = 1759
Score = 38.5 bits (88), Expect = 0.011
Identities = 32/113 (28%), Positives = 46/113 (40%), Gaps = 4/113 (3%)
Query: 290 AHQPGPEGQEESTPQSDVTED----GESPEDPSGTEGQLSEEEKPDQQPLSGEEELEPEA 345
A PGP P+ GES ++ E +L EEE D + +E+ + E
Sbjct: 1646 AGDPGPPDAAAPGPREGAAAAAAAAGESSQEDEEEELELPEEEAEDDEDEDDDEDDDDED 1705
Query: 346 SDGSGSWEDAALLTEANLPAPAPASASAPVLETLGSSEPAGGALRQRPTCSSS 398
D ED +E +LP A +A A ++ A GA PT +SS
Sbjct: 1706 DDEDDDDEDLRTDSEESLPEAAAEAAGAGARTPALAALAALGAPGPAPTAASS 1758
Score = 37.7 bits (86), Expect = 0.018
Identities = 25/81 (30%), Positives = 39/81 (48%), Gaps = 4/81 (4%)
Query: 298 QEESTPQSDVTEDGESPEDPSGTEGQLSEEEKPDQQPLSGEEELEPEASD---GSGSWED 354
+EE + ED E +D + + +E+ D+ + EE PEA+ G+G+
Sbjct: 1679 EEELELPEEEAEDDEDEDDDEDDDDEDDDEDDDDEDLRTDSEESLPEAAAEAAGAGARTP 1738
Query: 355 A-ALLTEANLPAPAPASASAP 374
A A L P PAP +AS+P
Sbjct: 1739 ALAALAALGAPGPAPTAASSP 1759
>gi|156104891 general transcription factor IIF, polypeptide 1, 74kDa
[Homo sapiens]
Length = 517
Score = 38.1 bits (87), Expect = 0.014
Identities = 29/114 (25%), Positives = 58/114 (50%), Gaps = 13/114 (11%)
Query: 279 NSRKEVQRRISAHQP--GPEGQEESTPQSDVTEDGESPEDPSGTEGQLSEEEKPDQQPLS 336
+S++E + + A Q GP+G +E + S+ +E+ + PE+ EEE+ + P
Sbjct: 280 SSQEEPESKAKAPQQEEGPKGVDEQSDSSEESEEEKPPEED-------KEEEEEKKAPTP 332
Query: 337 GEEELEPEASDGSGSWEDAALLTEANLPAPAPASASAPVLETLGSSEPAGGALR 390
E++ ++S+ S S E++ + +EA+ + P E +P+GG+ R
Sbjct: 333 QEKKRRKDSSEESDSSEESDIDSEASSALFMAKKKTPPKRE----RKPSGGSSR 382
>gi|4826694 integral membrane protein DGCR2 [Homo sapiens]
Length = 550
Score = 37.4 bits (85), Expect = 0.024
Identities = 28/109 (25%), Positives = 43/109 (39%), Gaps = 6/109 (5%)
Query: 286 RRISAHQPGPEGQEESTPQSDVTEDGES------PEDPSGTEGQLSEEEKPDQQPLSGEE 339
RRI GP+G +++DGE P T + + +PD P E
Sbjct: 394 RRIPGFDYGPDGFGTGLTPLHLSDDGEGGTFHFHDPPPPYTAYKYPDIGQPDDPPPPYEA 453
Query: 340 ELEPEASDGSGSWEDAALLTEANLPAPAPASASAPVLETLGSSEPAGGA 388
+ P++ + +DA E +LPAP + +L L P GA
Sbjct: 454 SIHPDSVFYDPADDDAFEPVEVSLPAPGDGGSEGALLRRLEQPLPTAGA 502
>gi|194097398 protein tyrosine phosphatase, receptor type, G
precursor [Homo sapiens]
Length = 1445
Score = 37.4 bits (85), Expect = 0.024
Identities = 23/78 (29%), Positives = 34/78 (43%), Gaps = 10/78 (12%)
Query: 293 PGPEGQEESTPQSDVTEDGESPEDPSGTEGQLSEEEKPDQQPLSGEEELEPEASDGSGSW 352
PGP+G T + TE+GE E +G+ EE GE++ E + G
Sbjct: 562 PGPDGDSSPTKDGEGTEEGEKDEKSESEDGEREHEE-------DGEKDSEKKEKSGVTHA 614
Query: 353 EDAALLTEANLPAPAPAS 370
+ TE P+P P+S
Sbjct: 615 AEERNQTE---PSPTPSS 629
>gi|33286446 opioid growth factor receptor [Homo sapiens]
Length = 677
Score = 37.0 bits (84), Expect = 0.031
Identities = 27/82 (32%), Positives = 37/82 (45%), Gaps = 6/82 (7%)
Query: 294 GPEGQEESTPQSDVTEDGESPEDPSGTEGQLSEEEKPDQQPL--SGEEELE-PEASDG-- 348
G G +E TP S G SP P+G E S E P +P +G+E E P + G
Sbjct: 506 GRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPR 565
Query: 349 -SGSWEDAALLTEANLPAPAPA 369
+G D + + P P+PA
Sbjct: 566 PAGPAGDEPAESPSETPGPSPA 587
Score = 29.6 bits (65), Expect = 5.0
Identities = 23/90 (25%), Positives = 33/90 (36%), Gaps = 3/90 (3%)
Query: 277 RDNSRKEVQRRISAHQPGPEGQEESTPQSDVTEDGESPEDPSGTEGQLSEEEKPDQQPLS 336
RD + GP G E + S+ G P P+G E S E P P +
Sbjct: 591 RDEPAESPSETPGPRPAGPAGDEPAESPSETP--GPRPAGPAGDEPAESPSETPGPSP-A 647
Query: 337 GEEELEPEASDGSGSWEDAALLTEANLPAP 366
G EP + + +DA + + A P
Sbjct: 648 GPTRDEPAKAGEAAELQDAEVESSAKSGKP 677
>gi|40254947 thioredoxin-related transmembrane protein 4 [Homo
sapiens]
Length = 349
Score = 37.0 bits (84), Expect = 0.031
Identities = 46/191 (24%), Positives = 71/191 (37%), Gaps = 27/191 (14%)
Query: 211 GAYLRIHAHFTGLRYLLYNFPMTCAFIGVASNFTFLSVIVLFSYMQWVWGGI-------W 263
G +H +FT + P C+++ F ++ +V +M V I
Sbjct: 168 GKIWHLHNYFT----VTLGIPAWCSYV-----FFVIATLVFGLFMGLVLVVISECFYVPL 218
Query: 264 PRHRFSLQVNIRKRDNSRKEVQRRISAHQPGPEGQEESTPQS--DVTEDGESPEDPSGTE 321
PRH ++ R N R E R Q E +++S + D D E ++ G E
Sbjct: 219 PRH-----LSERSEQNRRSEEAHRAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDE 273
Query: 322 GQLSEEEKPDQQPLSGEEELEPEASDGSGSWEDAALLTEANLPAPAPASASAPVLETLGS 381
+ EEE+ D +G +E EA+D ED E P A
Sbjct: 274 DEAEEEEEEDNL-AAGVDEERSEANDQGPPGEDGVTREEVE---PEEAEEGISEQPCPAD 329
Query: 382 SEPAGGALRQR 392
+E +LRQR
Sbjct: 330 TEVVEDSLRQR 340
>gi|115511012 coiled-coil domain containing 136 [Homo sapiens]
Length = 1154
Score = 36.6 bits (83), Expect = 0.041
Identities = 27/101 (26%), Positives = 46/101 (45%), Gaps = 9/101 (8%)
Query: 275 RKRDNSRKEVQRRISAHQPGPEGQEESTPQ--SDVTEDGESPEDPSGTEGQLSEEEKPDQ 332
RK D KE +++ + + +EE+ Q ++ + PE+ TE Q EE + D+
Sbjct: 1028 RKLDGLAKEEEKKEEMEEEKKQVKEEAKEQCGDELVAEPADPEEAKSTEDQ--EENEEDK 1085
Query: 333 QPLSGEEELEPEASDGSGSWE-----DAALLTEANLPAPAP 368
+ EE+ E E D S E + L+E+ +P P
Sbjct: 1086 EEEEKEEDSEEEEDDADSSLESPEENNPLRLSESKKSSPTP 1126
>gi|34482047 adaptor-related protein complex 3, beta 2 subunit [Homo
sapiens]
Length = 1082
Score = 36.2 bits (82), Expect = 0.053
Identities = 27/99 (27%), Positives = 41/99 (41%), Gaps = 5/99 (5%)
Query: 279 NSRKEVQRRISAHQPGPEGQEESTPQSDVTEDGESPEDPSGTEGQLSEEE-----KPDQQ 333
+S E + + G ES+ +SD + E E G+E + SEE+ K
Sbjct: 692 DSDPESESESDSKSSSESGSGESSSESDNEDQDEDEEKGRGSESEQSEEDGKRKTKKKVP 751
Query: 334 PLSGEEELEPEASDGSGSWEDAALLTEANLPAPAPASAS 372
GE E SD S S ++ + +E+ PAS S
Sbjct: 752 ERKGEASSSDEGSDSSSSSSESEMTSESEEEQLEPASWS 790
Score = 32.3 bits (72), Expect = 0.77
Identities = 25/87 (28%), Positives = 40/87 (45%), Gaps = 8/87 (9%)
Query: 281 RKEVQRRI---SAHQPGPEGQEESTPQSDVTEDGESPEDPSGTEGQLSEEEKPDQQPLSG 337
RKE ++ S + GP +S P+S+ D +S + SG+ SE + DQ
Sbjct: 670 RKEKEKPFYSDSEGESGPTESADSDPESESESDSKSSSE-SGSGESSSESDNEDQD---- 724
Query: 338 EEELEPEASDGSGSWEDAALLTEANLP 364
E+E + S+ S ED T+ +P
Sbjct: 725 EDEEKGRGSESEQSEEDGKRKTKKKVP 751
>gi|218505694 potassium channel tetramerisation domain containing 1
isoform b [Homo sapiens]
Length = 865
Score = 36.2 bits (82), Expect = 0.053
Identities = 19/53 (35%), Positives = 28/53 (52%)
Query: 296 EGQEESTPQSDVTEDGESPEDPSGTEGQLSEEEKPDQQPLSGEEELEPEASDG 348
E +E+ + +T D E ED G + EEE+ ++ L +E LEPE S G
Sbjct: 60 EEEEDEIQEVQITGDEEEEEDGGGGLEEDEEEEEEEEMGLDWDEPLEPEDSAG 112
>gi|58331268 excision repair protein ERCC6-like [Homo sapiens]
Length = 1250
Score = 36.2 bits (82), Expect = 0.053
Identities = 33/115 (28%), Positives = 51/115 (44%), Gaps = 12/115 (10%)
Query: 264 PRHRFSLQV--NIRKRDNSRKEVQRRISAHQPGPEGQEESTPQSDVTEDGESPED--PSG 319
P FS Q+ ++ K NSR+ + R S + E+ + D + + + PED G
Sbjct: 1071 PGRFFSSQIPSSVNKSMNSRRSLASRRSLINMVLDHVEDMEERLDDSSEAKGPEDYPEEG 1130
Query: 320 TEGQLSEEEKPDQQPLSGEEELEPEASDGSGSW----EDAALLTEANLPAPAPAS 370
E E K ++ SGE +S+ SW + +AL E +L AP P S
Sbjct: 1131 VEESSGEASKYTEEDPSGETL----SSENKSSWLMTSKPSALAQETSLGAPEPLS 1181
>gi|4506411 Ran GTPase activating protein 1 [Homo sapiens]
Length = 587
Score = 36.2 bits (82), Expect = 0.053
Identities = 23/70 (32%), Positives = 32/70 (45%), Gaps = 4/70 (5%)
Query: 309 EDGESPEDPSGTEGQLSEEEKPDQQPLSGEEELEPEASDGSGSWEDAAL----LTEANLP 364
ED E E+ E + EEE+ D++ EEE E E G E +A + + N
Sbjct: 361 EDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQGEKSATPSRKILDPNTG 420
Query: 365 APAPASASAP 374
PAP +S P
Sbjct: 421 EPAPVLSSPP 430
>gi|17975763 myelin transcription factor 1 [Homo sapiens]
Length = 1121
Score = 35.8 bits (81), Expect = 0.070
Identities = 23/88 (26%), Positives = 39/88 (44%), Gaps = 4/88 (4%)
Query: 285 QRRISAHQPGPEGQEESTPQSDVTEDGESPEDPSGTEGQLSEEEKPDQQPLSGEEELEPE 344
Q+ I +H+ E +EE + + E+ E E+ E + EEE+ +++ EEE P+
Sbjct: 251 QKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPD 310
Query: 345 A----SDGSGSWEDAALLTEANLPAPAP 368
S + A L P+P P
Sbjct: 311 VIFQEDTSHTSAQKAPELRGPESPSPKP 338
Score = 30.0 bits (66), Expect = 3.8
Identities = 16/61 (26%), Positives = 29/61 (47%)
Query: 289 SAHQPGPEGQEESTPQSDVTEDGESPEDPSGTEGQLSEEEKPDQQPLSGEEELEPEASDG 348
S+ Q G EE + + E+ E ++ E + EEE+ +++ EEE E E +
Sbjct: 248 SSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEA 307
Query: 349 S 349
+
Sbjct: 308 A 308
>gi|57634514 SPANX-N2 protein [Homo sapiens]
Length = 180
Score = 35.8 bits (81), Expect = 0.070
Identities = 31/114 (27%), Positives = 48/114 (42%), Gaps = 8/114 (7%)
Query: 275 RKRDNSRKEVQRRISAHQPGPEGQEESTPQSDVTE-DGESPEDPSGTEGQLSEEEKPDQQ 333
+ R+NS VQ EG + D +E + ED +EG E+E D
Sbjct: 72 QSRENSINPVQEEEDEGLDSAEGSSQEDEDLDSSEGSSQEDEDLDSSEGSSQEDEDLDSS 131
Query: 334 PLSGEEELEPEASDGSGSWEDAALLTEANLPAPAPASASAPVLETLGSSEPAGG 387
S +E+ + ++S+GS S ED +L P +S L++ S GG
Sbjct: 132 EGSSQEDEDLDSSEGS-SQED------EDLDPPEGSSQEDEDLDSSEGSSQEGG 178
>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
Length = 2217
Score = 35.8 bits (81), Expect = 0.070
Identities = 29/103 (28%), Positives = 44/103 (42%), Gaps = 6/103 (5%)
Query: 290 AHQPGPEGQEESTPQSDVTEDGESPEDPSGTEGQLSEEEKPDQQPLSGEEELEPEASDGS 349
A P PE E S P + E+ +D + + QLS +E+P ++L +A +
Sbjct: 1319 AEHPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPS---FLASQQLLSQAGPSN 1375
Query: 350 GSWEDAALLTEANLPAPA-PASASAPVLETLGSSEPAGGALRQ 391
A L ++ P A P +AP T+ EPA G Q
Sbjct: 1376 PPGAPPAPLAPSSPPVTALPQDGAAPATSTM--PEPASGTASQ 1416
>gi|153945734 teashirt zinc finger homeobox 2 [Homo sapiens]
Length = 1034
Score = 35.8 bits (81), Expect = 0.070
Identities = 35/129 (27%), Positives = 55/129 (42%), Gaps = 13/129 (10%)
Query: 274 IRKRDNSRKEVQRRISAHQPGPEGQEESTPQSDVTEDGESPEDPSGTE-GQLSEEEKPDQ 332
++K + E + P E S + D E+P + TE G L EEEK +
Sbjct: 600 VKKESEDKDEAVKECGKESPHEEASSFSHSEGDSFRKSETPPEAKKTELGPLKEEEKLMK 659
Query: 333 QPLSGEEELEPEASDGSGSWEDAALLTE--ANLPAPAPASASAPVLET-LG-SSEPAGGA 388
+ G E+ +P+ + + + + L LP P SA VL LG ++EP
Sbjct: 660 E---GSEKEKPQPLEPTSALSNGCALANHAPALPCINPLSALQSVLNNHLGKATEPL--- 713
Query: 389 LRQRPTCSS 397
+ P+CSS
Sbjct: 714 --RSPSCSS 720
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 35.4 bits (80), Expect = 0.091
Identities = 29/109 (26%), Positives = 41/109 (37%), Gaps = 10/109 (9%)
Query: 299 EESTPQSDVTEDGESPEDPSGTEGQLSEEEKPDQQPLSG----------EEELEPEASDG 348
EE T ++ VTE+ E+ E + EEE +++ G EE PE
Sbjct: 458 EEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAK 517
Query: 349 SGSWEDAALLTEANLPAPAPASASAPVLETLGSSEPAGGALRQRPTCSS 397
S E+A EA P A + A V + PA + P S
Sbjct: 518 SPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKS 566
>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
[Homo sapiens]
Length = 2073
Score = 35.4 bits (80), Expect = 0.091
Identities = 26/74 (35%), Positives = 36/74 (48%), Gaps = 5/74 (6%)
Query: 282 KEVQRRISAHQPGPEGQEEST--PQSDVTEDGESPEDPSGTEGQLSEEEKPDQQPLSGEE 339
+EV+ A P E + E T P S T GE PED + EEE+ +++ EE
Sbjct: 1309 EEVKETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEE---EE 1365
Query: 340 ELEPEASDGSGSWE 353
E E E +G G+ E
Sbjct: 1366 EEEGEEEEGGGNVE 1379
Score = 30.4 bits (67), Expect = 2.9
Identities = 22/66 (33%), Positives = 28/66 (42%), Gaps = 12/66 (18%)
Query: 296 EGQEESTPQSDVTEDGESPE-------DPSGTEGQLSEE-----EKPDQQPLSGEEELEP 343
E +EE + + E+GE E DP G + Q EE EK D L EE E
Sbjct: 1354 EEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEE 1413
Query: 344 EASDGS 349
E + S
Sbjct: 1414 EDEEPS 1419
>gi|169207217 PREDICTED: zinc finger homeobox 2 [Homo sapiens]
Length = 2790
Score = 35.0 bits (79), Expect = 0.12
Identities = 23/73 (31%), Positives = 34/73 (46%), Gaps = 12/73 (16%)
Query: 297 GQEESTPQSDVTEDGESPEDPSGTEGQLSEEEKPDQQPLSGEEELEPEASDGSGSWEDAA 356
G+EE + + E+ + E P+G EG L E P GEE + EA+ G +
Sbjct: 1926 GEEEEEVEEEEVEEEQGLEPPAGPEGPLPE-------PPDGEELSQAEATKAGGKEPE-- 1976
Query: 357 LLTEANLPAPAPA 369
E P+P+PA
Sbjct: 1977 ---EKATPSPSPA 1986
>gi|239752280 PREDICTED: similar to family with sequence similarity
48, member B2 [Homo sapiens]
Length = 779
Score = 35.0 bits (79), Expect = 0.12
Identities = 34/129 (26%), Positives = 49/129 (37%), Gaps = 17/129 (13%)
Query: 275 RKRDNSRKEVQRRISAHQPGPEGQEESTPQS-DVTEDGESPEDPSGTEGQLSEEEKPDQQ 333
R +++ VQ ++ PG S P S ++PE P Q S K ++
Sbjct: 365 RAVSQAQESVQSKVKG--PGKMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKH 422
Query: 334 P------------LSGEEELEPEASDG--SGSWEDAALLTEANLPAPAPASASAPVLETL 379
P +S P+ + + AA A PAPAPA A+AP L
Sbjct: 423 PPPRTQLPSSSGKISSGNSFPPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAAAPALAAA 482
Query: 380 GSSEPAGGA 388
+ AGGA
Sbjct: 483 AVAAAAGGA 491
>gi|169207592 PREDICTED: zinc finger homeobox 2 [Homo sapiens]
Length = 2706
Score = 35.0 bits (79), Expect = 0.12
Identities = 23/73 (31%), Positives = 34/73 (46%), Gaps = 12/73 (16%)
Query: 297 GQEESTPQSDVTEDGESPEDPSGTEGQLSEEEKPDQQPLSGEEELEPEASDGSGSWEDAA 356
G+EE + + E+ + E P+G EG L E P GEE + EA+ G +
Sbjct: 1842 GEEEEEVEEEEVEEEQGLEPPAGPEGPLPE-------PPDGEELSQAEATKAGGKEPE-- 1892
Query: 357 LLTEANLPAPAPA 369
E P+P+PA
Sbjct: 1893 ---EKATPSPSPA 1902
>gi|169207014 PREDICTED: zinc finger homeobox 2 [Homo sapiens]
Length = 2706
Score = 35.0 bits (79), Expect = 0.12
Identities = 23/73 (31%), Positives = 34/73 (46%), Gaps = 12/73 (16%)
Query: 297 GQEESTPQSDVTEDGESPEDPSGTEGQLSEEEKPDQQPLSGEEELEPEASDGSGSWEDAA 356
G+EE + + E+ + E P+G EG L E P GEE + EA+ G +
Sbjct: 1842 GEEEEEVEEEEVEEEQGLEPPAGPEGPLPE-------PPDGEELSQAEATKAGGKEPE-- 1892
Query: 357 LLTEANLPAPAPA 369
E P+P+PA
Sbjct: 1893 ---EKATPSPSPA 1902
>gi|5031579 A-kinase anchor protein 8 [Homo sapiens]
Length = 692
Score = 35.0 bits (79), Expect = 0.12
Identities = 30/96 (31%), Positives = 40/96 (41%), Gaps = 5/96 (5%)
Query: 293 PGPEGQEESTPQSDVTEDGESPEDPSGTEGQLSEEEKP-DQQPLSGEEELEPEASDGSGS 351
P PE E T+ E+ DP QL EE+ P G + EA++
Sbjct: 595 PAPESSGEPAEDEGPTDTAEAGSDPQAE--QLLEEQVPCGTAHEKGVPKARSEAAEAGNG 652
Query: 352 WEDAALLTEA--NLPAPAPASASAPVLETLGSSEPA 385
E A E+ APAPA+A A V +T S+ A
Sbjct: 653 AETMAAEAESAQTRVAPAPAAADAEVEQTDAESKDA 688
>gi|210032463 family with sequence similarity 48, member B2 [Homo
sapiens]
Length = 817
Score = 35.0 bits (79), Expect = 0.12
Identities = 34/129 (26%), Positives = 49/129 (37%), Gaps = 17/129 (13%)
Query: 275 RKRDNSRKEVQRRISAHQPGPEGQEESTPQS-DVTEDGESPEDPSGTEGQLSEEEKPDQQ 333
R +++ VQ ++ PG S P S ++PE P Q S K ++
Sbjct: 403 RAVSQAQESVQSKVKG--PGKMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKH 460
Query: 334 P------------LSGEEELEPEASDG--SGSWEDAALLTEANLPAPAPASASAPVLETL 379
P +S P+ + + AA A PAPAPA A+AP L
Sbjct: 461 PPPRTQLPSSSGKISSGNSFPPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAAAPALAAA 520
Query: 380 GSSEPAGGA 388
+ AGGA
Sbjct: 521 AVAAAAGGA 529
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.405
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,948,611
Number of Sequences: 37866
Number of extensions: 849859
Number of successful extensions: 7053
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 106
Number of HSP's successfully gapped in prelim test: 322
Number of HSP's that attempted gapping in prelim test: 5725
Number of HSP's gapped (non-prelim): 1291
length of query: 398
length of database: 18,247,518
effective HSP length: 104
effective length of query: 294
effective length of database: 14,309,454
effective search space: 4206979476
effective search space used: 4206979476
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.