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Search of human proteins with 39812378
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|39812378 RAN binding protein 9 [Homo sapiens]
(729 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|39812378 RAN binding protein 9 [Homo sapiens] 1509 0.0
gi|40538736 RAN binding protein 10 [Homo sapiens] 848 0.0
gi|14249554 SPRY domain containing 3 [Homo sapiens] 85 2e-16
gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens] 81 3e-15
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 80 5e-15
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 80 7e-15
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 80 7e-15
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 79 1e-14
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] 79 1e-14
gi|157168329 formin 1 [Homo sapiens] 76 1e-13
gi|160707881 formin 2 [Homo sapiens] 76 1e-13
gi|56118221 amyloid beta (A4) precursor protein-binding, family ... 74 6e-13
gi|163965366 nascent polypeptide-associated complex alpha subuni... 73 8e-13
gi|42544125 splicing factor 1 isoform 2 [Homo sapiens] 73 1e-12
gi|110832843 TBP-associated factor 4 [Homo sapiens] 72 2e-12
gi|7706501 WW domain binding protein 11 [Homo sapiens] 71 3e-12
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 70 7e-12
gi|56549694 enabled homolog isoform a [Homo sapiens] 69 1e-11
gi|39930375 enabled homolog isoform b [Homo sapiens] 69 1e-11
gi|52485606 formin-like 2 [Homo sapiens] 69 2e-11
gi|208431824 forkhead box I3 [Homo sapiens] 69 2e-11
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 69 2e-11
gi|153792074 proline rich 12 [Homo sapiens] 69 2e-11
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] 68 3e-11
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 67 4e-11
gi|47132519 Ras association and pleckstrin homology domains 1 is... 67 6e-11
gi|33356148 formin-like 1 [Homo sapiens] 67 6e-11
gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Ho... 67 8e-11
gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Ho... 67 8e-11
gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Ho... 67 8e-11
>gi|39812378 RAN binding protein 9 [Homo sapiens]
Length = 729
Score = 1509 bits (3908), Expect = 0.0
Identities = 729/729 (100%), Positives = 729/729 (100%)
Query: 1 MSGQPPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGL 60
MSGQPPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGL
Sbjct: 1 MSGQPPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGL 60
Query: 61 GAAAAALLLHPPPPPPPATAAPPPPPPPPPPPASAAAPASGPPAPPGLAAGPGPAGGAPT 120
GAAAAALLLHPPPPPPPATAAPPPPPPPPPPPASAAAPASGPPAPPGLAAGPGPAGGAPT
Sbjct: 61 GAAAAALLLHPPPPPPPATAAPPPPPPPPPPPASAAAPASGPPAPPGLAAGPGPAGGAPT 120
Query: 121 PALVAGSSAAAPFPHGDSALNEQEKELQRRLKRLYPAVDEQETPLPRSWSPKDKFSYIGL 180
PALVAGSSAAAPFPHGDSALNEQEKELQRRLKRLYPAVDEQETPLPRSWSPKDKFSYIGL
Sbjct: 121 PALVAGSSAAAPFPHGDSALNEQEKELQRRLKRLYPAVDEQETPLPRSWSPKDKFSYIGL 180
Query: 181 SQNNLRVHYKGHGKTPKDAASVRATHPIPAACGIYYFEVKIVSKGRDGYMGIGLSAQGVN 240
SQNNLRVHYKGHGKTPKDAASVRATHPIPAACGIYYFEVKIVSKGRDGYMGIGLSAQGVN
Sbjct: 181 SQNNLRVHYKGHGKTPKDAASVRATHPIPAACGIYYFEVKIVSKGRDGYMGIGLSAQGVN 240
Query: 241 MNRLPGWDKHSYGYHGDDGHSFCSSGTGQPYGPTFTTGDVIGCCVNLINNTCFYTKNGHS 300
MNRLPGWDKHSYGYHGDDGHSFCSSGTGQPYGPTFTTGDVIGCCVNLINNTCFYTKNGHS
Sbjct: 241 MNRLPGWDKHSYGYHGDDGHSFCSSGTGQPYGPTFTTGDVIGCCVNLINNTCFYTKNGHS 300
Query: 301 LGIAFTDLPPNLYPTVGLQTPGEVVDANFGQHPFVFDIEDYMREWRTKIQAQIDRFPIGD 360
LGIAFTDLPPNLYPTVGLQTPGEVVDANFGQHPFVFDIEDYMREWRTKIQAQIDRFPIGD
Sbjct: 301 LGIAFTDLPPNLYPTVGLQTPGEVVDANFGQHPFVFDIEDYMREWRTKIQAQIDRFPIGD 360
Query: 361 REGEWQTMIQKMVSSYLVHHGYCATAEAFARSTDQTVLEELASIKNRQRIQKLVLAGRMG 420
REGEWQTMIQKMVSSYLVHHGYCATAEAFARSTDQTVLEELASIKNRQRIQKLVLAGRMG
Sbjct: 361 REGEWQTMIQKMVSSYLVHHGYCATAEAFARSTDQTVLEELASIKNRQRIQKLVLAGRMG 420
Query: 421 EAIETTQQLYPSLLERNPNLLFTLKVRQFIEMVNGTDSEVRCLGGRSPKSQDSYPVSPRP 480
EAIETTQQLYPSLLERNPNLLFTLKVRQFIEMVNGTDSEVRCLGGRSPKSQDSYPVSPRP
Sbjct: 421 EAIETTQQLYPSLLERNPNLLFTLKVRQFIEMVNGTDSEVRCLGGRSPKSQDSYPVSPRP 480
Query: 481 FSSPSMSPSHGMNIHNLASGKGSTAHFSGFESCSNGVISNKAHQSYCHSNKHQSSNLNVP 540
FSSPSMSPSHGMNIHNLASGKGSTAHFSGFESCSNGVISNKAHQSYCHSNKHQSSNLNVP
Sbjct: 481 FSSPSMSPSHGMNIHNLASGKGSTAHFSGFESCSNGVISNKAHQSYCHSNKHQSSNLNVP 540
Query: 541 ELNSINMSRSQQVNNFTSNDVDMETDHYSNGVGETSSNGFLNGSSKHDHEMEDCDTEMEV 600
ELNSINMSRSQQVNNFTSNDVDMETDHYSNGVGETSSNGFLNGSSKHDHEMEDCDTEMEV
Sbjct: 541 ELNSINMSRSQQVNNFTSNDVDMETDHYSNGVGETSSNGFLNGSSKHDHEMEDCDTEMEV 600
Query: 601 DSSQLRRQLCGGSQAAIERMIHFGRELQAMSEQLRRDCGKNTANKKMLKDAFSLLAYSDP 660
DSSQLRRQLCGGSQAAIERMIHFGRELQAMSEQLRRDCGKNTANKKMLKDAFSLLAYSDP
Sbjct: 601 DSSQLRRQLCGGSQAAIERMIHFGRELQAMSEQLRRDCGKNTANKKMLKDAFSLLAYSDP 660
Query: 661 WNSPVGNQLDPIQREPVCSALNSAILETHNLPKQPPLALAMGQATQCLGLMARSGIGSCA 720
WNSPVGNQLDPIQREPVCSALNSAILETHNLPKQPPLALAMGQATQCLGLMARSGIGSCA
Sbjct: 661 WNSPVGNQLDPIQREPVCSALNSAILETHNLPKQPPLALAMGQATQCLGLMARSGIGSCA 720
Query: 721 FATVEDYLH 729
FATVEDYLH
Sbjct: 721 FATVEDYLH 729
>gi|40538736 RAN binding protein 10 [Homo sapiens]
Length = 620
Score = 848 bits (2191), Expect = 0.0
Identities = 435/658 (66%), Positives = 499/658 (75%), Gaps = 61/658 (9%)
Query: 93 ASAAAPASGPPAPPGLAAGPGPAGGAPTPALVAGSSAAAPFPHGDSALNEQEKELQRRLK 152
A+ A P +G P P G ++G G GG P+P E+EL RRL+
Sbjct: 3 AATADPGAGNPQP-GDSSGGGAGGGLPSPG---------------------EQELSRRLQ 40
Query: 153 RLYPAVDEQETPLPRSWSPKDKFSYIGLSQNNLRVHYKGHGKTPKDAASVRATHPIPAAC 212
RLYPAV++QETPLPRSWSPKDK++YIGLSQ NLRVHYKGHGK KDAASVRATHPIPAAC
Sbjct: 41 RLYPAVNQQETPLPRSWSPKDKYNYIGLSQGNLRVHYKGHGKNHKDAASVRATHPIPAAC 100
Query: 213 GIYYFEVKIVSKGRDGYMGIGLSAQGVNMNRLPGWDKHSYGYHGDDGHSFCSSGTGQPYG 272
GIYYFEVKIVSKGRDGYMGIGLSAQGVNMNRLPGWDKHSYGYHGDDGHSFCSSGTGQPYG
Sbjct: 101 GIYYFEVKIVSKGRDGYMGIGLSAQGVNMNRLPGWDKHSYGYHGDDGHSFCSSGTGQPYG 160
Query: 273 PTFTTGDVIGCCVNLINNTCFYTKNGHSLGIAFTDLPPNLYPTVGLQTPGEVVDANFGQH 332
PTFTTGDVIGCCVNLIN TCFYTKNGHSLGIAFTDLP NLYPTVGLQTPGE+VDANFGQ
Sbjct: 161 PTFTTGDVIGCCVNLINGTCFYTKNGHSLGIAFTDLPANLYPTVGLQTPGEIVDANFGQQ 220
Query: 333 PFVFDIEDYMREWRTKIQAQIDRFPIGDREGEWQTMIQKMVSSYLVHHGYCATAEAFARS 392
PF+FDIEDYMREWR K+Q + FPI R GEWQ ++Q MVSSYLVHHGYCATA AFAR
Sbjct: 221 PFLFDIEDYMREWRAKVQGTVHCFPISARLGEWQAVLQNMVSSYLVHHGYCATATAFARM 280
Query: 393 TDQTVLEELASIKNRQRIQKLVLAGRMGEAIETTQQLYPSLLERNPNLLFTLKVRQFIEM 452
T+ + EE ASIKNRQ+IQKLVL GR+GEAIETTQ+ YP LLE NPNLLF LK RQF+EM
Sbjct: 281 TETPIQEEQASIKNRQKIQKLVLEGRVGEAIETTQRFYPGLLEHNPNLLFMLKCRQFVEM 340
Query: 453 VNGTDSEVRCLGGRSPKSQDSYPVSPRPFSSPSMSPSHGMNIHNLASGKGSTAHFSGFE- 511
VNGTDSEVR L RSPKSQDSYP SPS+SP HG + S H +G +
Sbjct: 341 VNGTDSEVRSLSSRSPKSQDSYP------GSPSLSPRHGPS--------SSHMHNTGADS 386
Query: 512 -SCSNGVISNKAHQSY-------------CHSNKHQSSNLNVPELNSINMSRSQQVNNFT 557
SCSNGV S K+ Q++ S+ S++N E NS + ++SQ ++ T
Sbjct: 387 PSCSNGVASTKSKQNHSKYPAPSSSSSSSSSSSSSSPSSVNYSESNSTDSTKSQH-HSST 445
Query: 558 SN------DVDMETDHYSNGVGETSSNGFLNGSSKHDHEMEDCDTEMEVDSSQLRRQLCG 611
SN +++ME +HY NGV + S +NG+ KH+ D E +D RRQLCG
Sbjct: 446 SNQETSDSEMEMEAEHYPNGVLGSMSTRIVNGAYKHEDLQTD---ESSMDDRHPRRQLCG 502
Query: 612 GSQAAIERMIHFGRELQAMSEQLRRDCGKNTANKKMLKDAFSLLAYSDPWNSPVGNQLDP 671
G+QAA ER+I FGRELQA+SEQL R+ GKN A+ +ML+DAFSLLAYSDPW+ PVG QLDP
Sbjct: 503 GNQAATERIILFGRELQALSEQLGREYGKNLAHTEMLQDAFSLLAYSDPWSCPVGQQLDP 562
Query: 672 IQREPVCSALNSAILETHNLPKQPPLALAMGQATQCLGLMARSGIGSCAFATVEDYLH 729
IQREPVC+ALNSAILE+ NLPKQPPL LA+GQA++CL LMAR+G+GSC+FA V+DYLH
Sbjct: 563 IQREPVCAALNSAILESQNLPKQPPLMLALGQASECLRLMARAGLGSCSFARVDDYLH 620
>gi|14249554 SPRY domain containing 3 [Homo sapiens]
Length = 442
Score = 85.1 bits (209), Expect = 2e-16
Identities = 40/97 (41%), Positives = 54/97 (55%), Gaps = 2/97 (2%)
Query: 187 VHYKGHGKTPKDAASVRATHPIPAACGIYYFEVKIVSKGRDGYMGIGLSAQGVNMNRLPG 246
+ Y G GK+ D +A HP+ +YFEV+IV G Y+ +GL+ + NR PG
Sbjct: 233 LEYLGKGKSIVDVGLAQARHPLSTRS--HYFEVEIVDPGEKCYIALGLARKDYPKNRHPG 290
Query: 247 WDKHSYGYHGDDGHSFCSSGTGQPYGPTFTTGDVIGC 283
W + S YH DDG F SG G P+GP GD++GC
Sbjct: 291 WSRGSVAYHADDGKIFHGSGVGDPFGPRCYKGDIMGC 327
Score = 78.6 bits (192), Expect = 2e-14
Identities = 47/141 (33%), Positives = 70/141 (49%), Gaps = 11/141 (7%)
Query: 216 YFEVKIVSKGRDGYMGIGLSAQGVNMNRLPGWDKHSYGYHGDDGHSFCSSGTGQPYGPTF 275
YFEV IV G G + +GL Q +++ PGW S YH DDG + G+ +G
Sbjct: 80 YFEVSIVDSGVRGTIAVGLVPQYYSLDHQPGWLPDSVAYHADDGKLYNGRAKGRQFGSKC 139
Query: 276 TTGDVIGCCVNLIN-----NTCFYTKNGHSLGIAFTDLPPN-LYPTVGLQTPGEVV---- 325
+GD IGC + ++ F+TKNG +G + P+ L+P VG+ + GE V
Sbjct: 140 NSGDRIGCGIEPVSFDVQTAQIFFTKNGKRVGSTIMPMSPDGLFPAVGMHSLGEEVRLHL 199
Query: 326 DANFG-QHPFVFDIEDYMREW 345
+A G + V ++ Y EW
Sbjct: 200 NAELGREDDSVMMVDSYEDEW 220
>gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens]
Length = 502
Score = 81.3 bits (199), Expect = 3e-15
Identities = 54/140 (38%), Positives = 59/140 (42%), Gaps = 46/140 (32%)
Query: 4 QPPPPPPQQQQQQQQLSPPP--------PAALAPVSGVVLPAPPAVSAGSSPAGSPGGGA 55
+P PPPP + QL PP L PV + P PP +P G P G
Sbjct: 311 EPLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPP------TPRGPPPPGR 364
Query: 56 GGEGLGAAAAALLLHPPPPPPPATA----------------APPPPPPPPPPPASAAAPA 99
GG PPPPPPPAT PPPPPPPPPPP+S PA
Sbjct: 365 GG-------------PPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPA 411
Query: 100 SGPPAPPGL--AAGPGPAGG 117
PP PP L A G P GG
Sbjct: 412 P-PPLPPALVPAGGLAPGGG 430
Score = 50.4 bits (119), Expect = 6e-06
Identities = 36/98 (36%), Positives = 43/98 (43%), Gaps = 17/98 (17%)
Query: 3 GQPPPPPPQQQQQQQQLSPPPPAA-------------LAPVSGVVLPAPPAVSAGSSPAG 49
G PPPPPP + L PPPP A P SG PAPP + PAG
Sbjct: 365 GGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNG-PAPPPLPPALVPAG 423
Query: 50 --SPGGGAGGEGLGAAAAALLLHPPPPPPPATAAPPPP 85
+PGGG G L + L+ P P ++A PPP
Sbjct: 424 GLAPGGGRGAL-LDQIRQGIQLNKTPGAPESSALQPPP 460
Score = 43.1 bits (100), Expect = 0.001
Identities = 33/117 (28%), Positives = 39/117 (33%), Gaps = 42/117 (35%)
Query: 59 GLGAAAAALLLHPPPPPPPATA-----------------------------APPPP---- 85
GL A + P PPPP + APPPP
Sbjct: 299 GLEAVRQEMRRQEPLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRG 358
Query: 86 --------PPPPPPPASAAAPASGPPAPPGLAAGPGPAGGAPTPALVAGSSAAAPFP 134
PPPPPPPA+ + PP PPG P P P P + + AP P
Sbjct: 359 PPPPGRGGPPPPPPPATGRS-GPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPP 414
Score = 32.3 bits (72), Expect = 1.6
Identities = 18/52 (34%), Positives = 24/52 (46%), Gaps = 5/52 (9%)
Query: 85 PPPPPPPPASAAAPASGPPAPPGLAAGPGPAGGAPTPALVAGSSAAAPFPHG 136
P PPPPPP+ + P PP + G +G P P + G + P P G
Sbjct: 312 PLPPPPPPSRG---GNQLPRPPIVGGNKGRSG--PLPPVPLGIAPPPPTPRG 358
>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
tract binding protein associated) [Homo sapiens]
Length = 707
Score = 80.5 bits (197), Expect = 5e-15
Identities = 51/139 (36%), Positives = 59/139 (42%), Gaps = 13/139 (9%)
Query: 6 PPPPPQQQQQQQQLSPPPPAALAPVSGVVLP-------APPAVSAGSSPAGSPGGGAGGE 58
PPPPP QQQQQ PPP P P PP S P + G G
Sbjct: 61 PPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGP-AP 119
Query: 59 GLGAAAAALLLHPPPPPPPATAAP---PPPPPPPPPPASAAAPASGPPAPP--GLAAGPG 113
G+G+A A PP PP + A P P P P PPP ++A P + PP PP G+ P
Sbjct: 120 GVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPP 179
Query: 114 PAGGAPTPALVAGSSAAAP 132
AGG P P P
Sbjct: 180 QAGGPPPPPAAVPGPGPGP 198
Score = 74.7 bits (182), Expect = 3e-13
Identities = 58/172 (33%), Positives = 65/172 (37%), Gaps = 44/172 (25%)
Query: 5 PPP------PPPQQ---------------QQQQQQLSPPPP-------AALAPVSGVVLP 36
PPP PPPQQ Q QQQ PPPP A P +
Sbjct: 63 PPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVG 122
Query: 37 APPAVSAGSSPAGSPGGGA-GGEGLGAAAAALLLHPPPPPPPATAAPPPPPPPPPPPASA 95
+ P S+ + PA P GA G G G P P PPPA + PP PPP PP+S
Sbjct: 123 SAPPASSSAPPATPPTSGAPPGSGPG---------PTPTPPPAVTSAPPGAPPPTPPSSG 173
Query: 96 A----APASGPPAPPGLAAGPGPA--GGAPTPALVAGSSAAAPFPHGDSALN 141
A GPP PP GPGP G G P P G L+
Sbjct: 174 VPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGLS 225
Score = 73.2 bits (178), Expect = 8e-13
Identities = 53/141 (37%), Positives = 62/141 (43%), Gaps = 27/141 (19%)
Query: 4 QPPP--PPPQQQQQQQQLSPPPP-------AALAPVSGVVLPAPPAVSAGSSPAGSPGGG 54
QPPP PPP Q QQQ PPPP A P + + P S+ + PA P G
Sbjct: 81 QPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSG 140
Query: 55 AG-GEGLGAAAA---ALLLHPP---PPPPPATAAPPPPPP---PPPPPASAAAPASGPPA 104
A G G G A+ PP PP PP++ P PP PPPPPA+ P GP
Sbjct: 141 APPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQ 200
Query: 105 PPG--------LAAGPGPAGG 117
PG + GP P GG
Sbjct: 201 GPGPGGPKGGKMPGGPKPGGG 221
Score = 44.7 bits (104), Expect = 3e-04
Identities = 39/113 (34%), Positives = 43/113 (38%), Gaps = 24/113 (21%)
Query: 37 APPAVSAGSSPAGSPGGGAGGEGLGAAAAALLLHPPPPPPPATAAPPPPP--PPP----- 89
+PP + G G G G G P PPPPP PPP PPP
Sbjct: 33 SPPPGMGLNQNRGPMGPGPGQSGPKP--------PIPPPPPHQQQQQPPPQQPPPQQPPP 84
Query: 90 --PPPASAAAPASGPPAPPG------LAAGPGPAGGAPTPALVAGSSAAAPFP 134
PPP PP PP +A GPGPA G + A A SSA P
Sbjct: 85 HQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGS-APPASSSAPPATP 136
Score = 41.6 bits (96), Expect = 0.003
Identities = 37/121 (30%), Positives = 38/121 (31%), Gaps = 12/121 (9%)
Query: 3 GQPPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAG---GEG 59
G P PPP PP P P SGV P A PA PG G G G G
Sbjct: 148 GPTPTPPPAVTSAPPGAPPPTP----PSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPG 203
Query: 60 LGAAAAALLLHPPPPPPPATAAPPPPPPPPPPPASAAAPASG----PPAPPGLAAGPGPA 115
G + P P P P PP P G PP GP P
Sbjct: 204 PGGPKGG-KMPGGPKPGGGPGLSTPGGHPKPPHRGGGEPRGGRQHHPPYHQQHHQGPPPG 262
Query: 116 G 116
G
Sbjct: 263 G 263
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 80.1 bits (196), Expect = 7e-15
Identities = 57/160 (35%), Positives = 66/160 (41%), Gaps = 28/160 (17%)
Query: 5 PPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGS--SPAGSPGGGAG------ 56
PPPP P PPPP GV + +PP++ G+ SP G A
Sbjct: 588 PPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPP 647
Query: 57 -GEGLGAAAAALL----LHPPPPPPPATAAPPPPPPP-------PPPPASAAAPASGPPA 104
EG+G + + L PPPPP P +A PPPPPP PPPP A PP
Sbjct: 648 LPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPP 707
Query: 105 PPGLAAGPG-------PAG-GAPTPALVAGSSAAAPFPHG 136
PP L GPG P G G P P G PF G
Sbjct: 708 PPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFG 747
Score = 79.0 bits (193), Expect = 1e-14
Identities = 60/169 (35%), Positives = 72/169 (42%), Gaps = 24/169 (14%)
Query: 5 PPPPPPQQQQQQQQLSPPP--PAALA-----PVSG-VVLPAPPAVSAG---SSPAGSPGG 53
PPPPPP +S PP P A P+SG +P PP + G SP+ PGG
Sbjct: 604 PPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGG 663
Query: 54 GAGGEGLGAAAAALLLHPPPPPPPATAAPPPPPP--------PPPPPASAAAPASGPPAP 105
A +A + PPPPP P +A PPPPP PPPPP P PP P
Sbjct: 664 TAIPPPPPLPGSARI-PPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPP 722
Query: 106 ----PGLAAGPGPAGGAPTPALVAGSSAAAPFPHGDSALNEQEKELQRR 150
PG+ P G P P G AA P G + + E+Q R
Sbjct: 723 FPGGPGIPPPPPGMGMPPPPPFGFGVPAAPVLPFGLTPKKLYKPEVQLR 771
Score = 60.8 bits (146), Expect = 4e-09
Identities = 43/128 (33%), Positives = 53/128 (41%), Gaps = 30/128 (23%)
Query: 27 LAPVSGVVLPAPPAV-SAGSSPAGSPGGGAGGEGLGAAAAALLLHPPPPPP--PATAAPP 83
+A +S + PP+V S P P G G + PPPP P T PP
Sbjct: 553 MASLSAAAITVPPSVPSRAPVPPAPPLPGDSGT----------IIPPPPAPGDSTTPPPP 602
Query: 84 PPPPPPPPPASAAAPASGPPAPPGLAA----------------GPGPAG-GAPTPALVAG 126
PPPPPPPPP S PP+ PG A P P G G P+P+ + G
Sbjct: 603 PPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPG 662
Query: 127 SSAAAPFP 134
+A P P
Sbjct: 663 GTAIPPPP 670
Score = 49.7 bits (117), Expect = 1e-05
Identities = 38/111 (34%), Positives = 43/111 (38%), Gaps = 45/111 (40%)
Query: 2 SGQPPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLG 61
+G PPPPPP + + PPPP P P GG G+
Sbjct: 689 AGIPPPPPP--LPGEAGMPPPPP-----------PLP-----------------GGPGI- 717
Query: 62 AAAAALLLHPPPPPPPATAAPPPPPP----PPPPPASAAAPASGPPAPPGL 108
PPPPP P PPPPP PPPPP PA+ P P GL
Sbjct: 718 ---------PPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAA-PVLPFGL 758
Score = 43.1 bits (100), Expect = 0.001
Identities = 30/93 (32%), Positives = 43/93 (46%), Gaps = 15/93 (16%)
Query: 60 LGAAAAALLLHPPPPPPPATAAPPPPPPP---------PPPPASAAAPASGPPAPPGLAA 110
+ + +AA + PP P + AP PP PP PPPPA + PP PP
Sbjct: 553 MASLSAAAITVPPSVP---SRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPP 609
Query: 111 GPGPAGG--APTPALVAGSSAAAPFP-HGDSAL 140
P P G + P+L G++ + P P GD+ +
Sbjct: 610 PPLPGGVCISSPPSLPGGTAISPPPPLSGDATI 642
>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
Length = 1272
Score = 80.1 bits (196), Expect = 7e-15
Identities = 57/160 (35%), Positives = 66/160 (41%), Gaps = 28/160 (17%)
Query: 5 PPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGS--SPAGSPGGGAG------ 56
PPPP P PPPP GV + +PP++ G+ SP G A
Sbjct: 597 PPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPP 656
Query: 57 -GEGLGAAAAALL----LHPPPPPPPATAAPPPPPPP-------PPPPASAAAPASGPPA 104
EG+G + + L PPPPP P +A PPPPPP PPPP A PP
Sbjct: 657 LPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPP 716
Query: 105 PPGLAAGPG-------PAG-GAPTPALVAGSSAAAPFPHG 136
PP L GPG P G G P P G PF G
Sbjct: 717 PPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFG 756
Score = 79.0 bits (193), Expect = 1e-14
Identities = 60/169 (35%), Positives = 72/169 (42%), Gaps = 24/169 (14%)
Query: 5 PPPPPPQQQQQQQQLSPPP--PAALA-----PVSG-VVLPAPPAVSAG---SSPAGSPGG 53
PPPPPP +S PP P A P+SG +P PP + G SP+ PGG
Sbjct: 613 PPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGG 672
Query: 54 GAGGEGLGAAAAALLLHPPPPPPPATAAPPPPPP--------PPPPPASAAAPASGPPAP 105
A +A + PPPPP P +A PPPPP PPPPP P PP P
Sbjct: 673 TAIPPPPPLPGSARI-PPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPP 731
Query: 106 ----PGLAAGPGPAGGAPTPALVAGSSAAAPFPHGDSALNEQEKELQRR 150
PG+ P G P P G AA P G + + E+Q R
Sbjct: 732 FPGGPGIPPPPPGMGMPPPPPFGFGVPAAPVLPFGLTPKKLYKPEVQLR 780
Score = 60.8 bits (146), Expect = 4e-09
Identities = 43/128 (33%), Positives = 53/128 (41%), Gaps = 30/128 (23%)
Query: 27 LAPVSGVVLPAPPAV-SAGSSPAGSPGGGAGGEGLGAAAAALLLHPPPPPP--PATAAPP 83
+A +S + PP+V S P P G G + PPPP P T PP
Sbjct: 562 MASLSAAAITVPPSVPSRAPVPPAPPLPGDSGT----------IIPPPPAPGDSTTPPPP 611
Query: 84 PPPPPPPPPASAAAPASGPPAPPGLAA----------------GPGPAG-GAPTPALVAG 126
PPPPPPPPP S PP+ PG A P P G G P+P+ + G
Sbjct: 612 PPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPG 671
Query: 127 SSAAAPFP 134
+A P P
Sbjct: 672 GTAIPPPP 679
Score = 49.7 bits (117), Expect = 1e-05
Identities = 38/111 (34%), Positives = 43/111 (38%), Gaps = 45/111 (40%)
Query: 2 SGQPPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLG 61
+G PPPPPP + + PPPP P P GG G+
Sbjct: 698 AGIPPPPPP--LPGEAGMPPPPP-----------PLP-----------------GGPGI- 726
Query: 62 AAAAALLLHPPPPPPPATAAPPPPPP----PPPPPASAAAPASGPPAPPGL 108
PPPPP P PPPPP PPPPP PA+ P P GL
Sbjct: 727 ---------PPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAA-PVLPFGL 767
Score = 43.1 bits (100), Expect = 0.001
Identities = 30/93 (32%), Positives = 43/93 (46%), Gaps = 15/93 (16%)
Query: 60 LGAAAAALLLHPPPPPPPATAAPPPPPPP---------PPPPASAAAPASGPPAPPGLAA 110
+ + +AA + PP P + AP PP PP PPPPA + PP PP
Sbjct: 562 MASLSAAAITVPPSVP---SRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPP 618
Query: 111 GPGPAGG--APTPALVAGSSAAAPFP-HGDSAL 140
P P G + P+L G++ + P P GD+ +
Sbjct: 619 PPLPGGVCISSPPSLPGGTAISPPPPLSGDATI 651
>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
sapiens]
Length = 505
Score = 79.3 bits (194), Expect = 1e-14
Identities = 49/123 (39%), Positives = 56/123 (45%), Gaps = 25/123 (20%)
Query: 4 QPPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGAA 63
Q PPPPP + PPP P PP ++G P + G GA A
Sbjct: 275 QAPPPPPPSRG-----GPPP------------PPPPPHNSGPPPPPARGRGAPPPPPSRA 317
Query: 64 AAALLLHPPPPPP--PATAAPPPPPP---PPPPPASAAAPASGPPAPPGLAAGPGPAGGA 118
A PPPPPP P+ A PPPPP PPPPPA ++ SGPP PP G GP
Sbjct: 318 PTAA---PPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPP 374
Query: 119 PTP 121
P P
Sbjct: 375 PPP 377
Score = 71.6 bits (174), Expect = 2e-12
Identities = 48/151 (31%), Positives = 65/151 (43%), Gaps = 28/151 (18%)
Query: 3 GQPPPPPPQQQQ------QQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAG 56
G PPPPPP + + +PPPP + AP + P PP+ + + P P
Sbjct: 286 GPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPP-PPPPSRPSVAVPPPPPNR--- 341
Query: 57 GEGLGAAAAALLLHPPPPPPPATAAPPPPPPPPPPPASAAAPASGPPAPPGLAAGPGPAG 116
++PPPPP ++AP PPPPPP A PP PP P P G
Sbjct: 342 ------------MYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPP-----PPPPG 384
Query: 117 GAPTPALVAGSSAAAPFPHGD-SALNEQEKE 146
P P L + P G+ +AL +Q +E
Sbjct: 385 PPPPPGLPSDGDHQVPTTAGNKAALLDQIRE 415
Score = 60.8 bits (146), Expect = 4e-09
Identities = 35/98 (35%), Positives = 43/98 (43%), Gaps = 22/98 (22%)
Query: 59 GLGAAAAALLLHPPPPPPPATAAPPPPPPPP---------------PPPASAAAPASGPP 103
G+ A L PPPPPP+ PPPPPPPP PPP + AP + PP
Sbjct: 264 GVEAVKNELRRQAPPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPP 323
Query: 104 AP----PGLAAGPGPAG---GAPTPALVAGSSAAAPFP 134
P P +A P P P PAL + + + P P
Sbjct: 324 PPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPP 361
>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
Length = 639
Score = 79.0 bits (193), Expect = 1e-14
Identities = 52/147 (35%), Positives = 65/147 (44%), Gaps = 27/147 (18%)
Query: 2 SGQPPPPP----PQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGG 57
SGQPPPPP P QQQQQQ PPPP + + S LP + ++ AG+
Sbjct: 486 SGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQ 545
Query: 58 EGLGAAAAA-----------LLLHPPPPPPPATAAPPPPPPPPPPPASAAAPASGPPAPP 106
+ AAAA+ ++ PP PP PPPPPPPPP ++ A PP PP
Sbjct: 546 QQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMYAPPPPPPP 605
Query: 107 GL------------AAGPGPAGGAPTP 121
+ AG P G P P
Sbjct: 606 PMDPSNFVTMMGMGVAGMPPFGMPPAP 632
Score = 59.7 bits (143), Expect = 9e-09
Identities = 49/154 (31%), Positives = 60/154 (38%), Gaps = 27/154 (17%)
Query: 7 PPPPQQQQQQQQLSPPPPAALAP-VSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGAAAA 65
PPPP Q PPPP P G P P GS+P GS G +G G
Sbjct: 420 PPPPWMQP------PPPPMNQGPHPPGHHGPPPMDQYLGSTPVGS-GVYRLHQGKGMMPP 472
Query: 66 ALLLHPPPPPPPATAAPPPPPP------------PPPPPASAAAPASGPPAP-------P 106
+ PPPPPP + PPPPP PPPPP +++ AS P P
Sbjct: 473 PPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTT 532
Query: 107 GLAAGPGPAGGAPTPALVAGSSAAAPFPHGDSAL 140
+AG G A +S AP G+ +
Sbjct: 533 TTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTM 566
Score = 45.4 bits (106), Expect = 2e-04
Identities = 42/154 (27%), Positives = 53/154 (34%), Gaps = 61/154 (39%)
Query: 20 SPPPPAALAPVSGVVLPAPPAVSAGSSPA----GSPGGGAGGEGLGAAAAALLL------ 69
+PPPP+ ++ PP +++G S + G GGG GG G G + L
Sbjct: 352 NPPPPSLMSTTQS----RPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGG 407
Query: 70 --------HPPPPPPPATAAPPPP------------PPP--------------------- 88
+P PPPP PPPP PPP
Sbjct: 408 HGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGK 467
Query: 89 ---PPPPASAAAPASGPPAPPGLAAGPGPAGGAP 119
PPPP P PP PP P P+G P
Sbjct: 468 GMMPPPPMGMMPP---PPPPPSGQPPPPPSGPLP 498
Score = 42.7 bits (99), Expect = 0.001
Identities = 38/147 (25%), Positives = 50/147 (34%), Gaps = 14/147 (9%)
Query: 4 QPPPPPPQQQQQQQQLSPPPPA----ALAPV-SGVV-------LPAPPAVSAGSSPAGSP 51
QPPPPP Q PPP PV SGV + PP + P P
Sbjct: 426 QPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPP 485
Query: 52 GGGAGGEGLGAAAA--ALLLHPPPPPPPATAAPPPPPPPPPPPASAAAPASGPPAPPGLA 109
G G PPPPPPP+++ P P + ++G + P
Sbjct: 486 SGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQ 545
Query: 110 AGPGPAGGAPTPALVAGSSAAAPFPHG 136
A +P + G+ P P G
Sbjct: 546 QQQAAAAASPGAPQMQGNPTMVPLPPG 572
Score = 34.3 bits (77), Expect = 0.42
Identities = 30/113 (26%), Positives = 43/113 (38%), Gaps = 15/113 (13%)
Query: 7 PPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGAAAAA 66
P PQ Q + ++ + +A + P P +V + S PA +P A AA
Sbjct: 297 PGDPQSAQDKARMDKEYLSLMAELGEA--PVPASVGSTSGPATTPLASA------PRPAA 348
Query: 67 LLLHPPPPPPPATAAPPPPPPPPPPPASAAAPASGPPAPPGLAAGPGPAGGAP 119
+PPPP +T PP + P+ P GPG GG P
Sbjct: 349 PANNPPPPSLMSTT-------QSRPPWMNSGPSESRPYHGMHGGGPGGPGGGP 394
>gi|157168329 formin 1 [Homo sapiens]
Length = 1196
Score = 75.9 bits (185), Expect = 1e-13
Identities = 47/117 (40%), Positives = 54/117 (46%), Gaps = 25/117 (21%)
Query: 8 PPPQQQQQQQQLSPPPPAALAPVS------GVVLPAPPAVSAGSSPAGSPGGGAGGEGLG 61
P QQ+ PPPPA++ P G + PAPP + P P
Sbjct: 633 PMEGMASNQQKALPPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPP------ 686
Query: 62 AAAAALLLHPPPPPPPATAAPPPPPPPPPPPASAAAPASG--PPA--PPGLAAGPGP 114
PPP PPP++A PPPPPPPPP P S A P G PPA PPGLA P P
Sbjct: 687 ---------PPPLPPPSSAGPPPPPPPPPLPNSPAPPNPGGPPPAPPPPGLAPPPPP 734
Score = 71.6 bits (174), Expect = 2e-12
Identities = 59/168 (35%), Positives = 70/168 (41%), Gaps = 34/168 (20%)
Query: 18 QLSPPPP-----AALAPVSGVV------LPAPPAVSAGSSPAGSPGGGAGGEGLGAAAAA 66
QLSPP AAL P+ G+ LP PPA P S GLG+
Sbjct: 617 QLSPPNDHKDIHAALQPMEGMASNQQKALPPPPASIPPPPPLPS--------GLGS---- 664
Query: 67 LLLHPPPPPPPATAAPP---PPPPPPP-PPASAAAPASGPPAPPGLAAGPGPAGGAPTPA 122
L P PP PP +A PP PPPPPPP PP S+A P PP PP + P G P PA
Sbjct: 665 --LSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPPPPPLPNSPAPPNPGGPPPA 722
Query: 123 LVAGSSAAAPFPHGDSALNEQEKELQRRLKRLYPAVDEQETPLPRSWS 170
A P P L + R+ PA++ P W+
Sbjct: 723 PPPPGLAPPPPPGLFFGLGSSSSQCPRK-----PAIEPSCPMKPLYWT 765
Score = 57.0 bits (136), Expect = 6e-08
Identities = 41/114 (35%), Positives = 43/114 (37%), Gaps = 50/114 (43%)
Query: 2 SGQPPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLG 61
+G P PPPP PPPP PP SAG P
Sbjct: 676 AGPPLPPPP----------PPPPPL-----------PPPSSAGPPPP------------- 701
Query: 62 AAAAALLLHPPPPPPPATAAPPPP--PPPPPPPASAAAPASGPPAPPGLAAGPG 113
PPPPP P + APP P PPP PPP P PP PPGL G G
Sbjct: 702 ---------PPPPPLPNSPAPPNPGGPPPAPPP-----PGLAPPPPPGLFFGLG 741
Score = 32.3 bits (72), Expect = 1.6
Identities = 15/46 (32%), Positives = 19/46 (41%)
Query: 5 PPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGS 50
PPPPPP +P P P G+ P PP + G + S
Sbjct: 700 PPPPPPPLPNSPAPPNPGGPPPAPPPPGLAPPPPPGLFFGLGSSSS 745
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 75.9 bits (185), Expect = 1e-13
Identities = 53/156 (33%), Positives = 62/156 (39%), Gaps = 44/156 (28%)
Query: 5 PPPPPPQQQQQQQQLSPPPPAA------LAPVSGVVLPAPPAVSAGSSPAGSPGGGAG-- 56
PPPPPP + PPPP L P+ G +P PP + + P P GAG
Sbjct: 909 PPPPPPLPGAG---IPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIP 965
Query: 57 ------GEGLGAAAAALLLHPPPPPPPATAAPPPPP------PPPPP------PASAAAP 98
G G+ PPPPP P PPPPP PPPPP P P
Sbjct: 966 LPPPLPGAGI----------PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1015
Query: 99 ASGPPAPPGLAAGPGPAGGAPTPALVAGSSAAAPFP 134
+G P PP P P G P P + G+ P P
Sbjct: 1016 GAGIPPPP-----PLPGAGIPPPPPLPGAGIPPPPP 1046
Score = 73.6 bits (179), Expect = 6e-13
Identities = 51/145 (35%), Positives = 59/145 (40%), Gaps = 28/145 (19%)
Query: 2 SGQPPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLG 61
+G PPPPP PPPP P+ G +P PP + P P GAG
Sbjct: 940 AGIPPPPP-----LPGAAIPPPP----PLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPP 990
Query: 62 AAAAALLLHPPPPPPPATAAPPPPP------PPPPP------PASAAAPASGPPAPPGLA 109
A + PPPPP P PPPPP PPPPP P P +G P PP
Sbjct: 991 PLPGAGI--PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP--- 1045
Query: 110 AGPGPAGGAPTPALVAGSSAAAPFP 134
P P G P P + G+ P P
Sbjct: 1046 --PLPGAGIPPPPPLPGAGIPPPPP 1068
Score = 72.8 bits (177), Expect = 1e-12
Identities = 54/156 (34%), Positives = 61/156 (39%), Gaps = 24/156 (15%)
Query: 1 MSGQPPPPPPQQQQQQQQLSPPPPAA----LAPVSGVVLPAPPAVSAGSSPAGSPGGGAG 56
+ G PPPP L PP P A P+ G +P PP + P P GAG
Sbjct: 948 LPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1007
Query: 57 GEGLGAAAAALLLHPPPPPPPATAAPPPPP------PPPPPPASAAAP-------ASGPP 103
A + PPPPP P PPPPP PPPPP A P A PP
Sbjct: 1008 IPPPPPLPGAGI--PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1065
Query: 104 APPGLAAG-----PGPAGGAPTPALVAGSSAAAPFP 134
PP AG P P G P P + G+ P P
Sbjct: 1066 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1101
Score = 72.4 bits (176), Expect = 1e-12
Identities = 54/164 (32%), Positives = 63/164 (38%), Gaps = 33/164 (20%)
Query: 2 SGQPPPPP-------PQQQQQQQQLSPPPPAALA------PVSGVVLPAPPAVSAGSSPA 48
+G PPPPP P + PPPP A P+ G +P PP + P
Sbjct: 1017 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1076
Query: 49 GSPGGGAGGEGLGAAAAALLLHPPPPPPPATAAPPPPP------PPPPP------PASAA 96
P GAG A + PPPPP P PPPPP PPPPP P
Sbjct: 1077 PPPLPGAGIPPPPPLPGAGI--PPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1134
Query: 97 APASGPPAPPGL------AAGPGPAGGAPTPALVAGSSAAAPFP 134
P +G P PP L P P G P P + G+ P P
Sbjct: 1135 LPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1178
Score = 68.9 bits (167), Expect = 2e-11
Identities = 52/147 (35%), Positives = 58/147 (39%), Gaps = 37/147 (25%)
Query: 6 PPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGAAAA 65
P PPP Q + L PPPP P+ G +P PP + P GAG
Sbjct: 897 PQPPPLQGTEM--LPPPPP----PLPGAGIPPPPPLPGAGILPLPPLPGAG--------- 941
Query: 66 ALLLHPPPPPPPATAAPPPPP------PPPPPPASAAAP-------ASGPPAPPGLAAG- 111
PPPPP P A PPPPP P PPP A P A PP PP AG
Sbjct: 942 ----IPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 997
Query: 112 ----PGPAGGAPTPALVAGSSAAAPFP 134
P P G P P + G+ P P
Sbjct: 998 PPPPPLPGAGIPPPPPLPGAGIPPPPP 1024
Score = 68.6 bits (166), Expect = 2e-11
Identities = 52/151 (34%), Positives = 59/151 (39%), Gaps = 40/151 (26%)
Query: 2 SGQPPPPP-------PQQQQQQQQLSPPPPAALA------PVSGVVLPAPPAVSAGSSPA 48
+G PPPPP P + PPPP A P+ GV +P PP + P
Sbjct: 1061 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPP 1120
Query: 49 GSPGGGAGGEGLGAAAAALLLHPPPPPPPATAAPPPPP--P---PPPPPASAAAPASGPP 103
P GAG PPPPP P PPPPP PPPPP P +G P
Sbjct: 1121 PPPLPGAG-------------IPPPPPLPGAGIPPPPPLPRVGIPPPPP----LPGAGIP 1163
Query: 104 APPGLAAGPGPAGGAPTPALVAGSSAAAPFP 134
PP P P G P P + G P P
Sbjct: 1164 PPP-----PLPGAGIPPPPPLPGVGIPPPPP 1189
Score = 66.6 bits (161), Expect = 8e-11
Identities = 56/180 (31%), Positives = 67/180 (37%), Gaps = 46/180 (25%)
Query: 2 SGQPPPPP-------PQQQQQQQQLSPPPPAALA------PVSGVVLPAPPAVSAGSSPA 48
+G PPPPP P + PPPP A P+ GV +P PP + P
Sbjct: 1138 AGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPP 1197
Query: 49 GSPGGGAGGEGLGAAAAALLLHPPPPPPPATAAPPPPPPPPPPPASA-----AAPASGPP 103
P GAG PPPPP P PP P PP PPP + P SGPP
Sbjct: 1198 PPPLPGAG-------------IPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPP 1244
Query: 104 APPGLAAGPGPAGGAPTPALVAGSSAAAPFPHG--------DSALNEQEKELQRRLKRLY 155
P + + PTP + P P G D +Q E R +K LY
Sbjct: 1245 LLPQVGSST-----LPTPQVC--GFLPPPLPSGLFGLGMNQDKGSRKQPIEPCRPMKPLY 1297
Score = 62.0 bits (149), Expect = 2e-09
Identities = 47/153 (30%), Positives = 60/153 (39%), Gaps = 38/153 (24%)
Query: 3 GQPPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGA 62
GQP PP + Q S + A + +P+PP + S + PG G
Sbjct: 823 GQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLG-------- 874
Query: 63 AAAALLLHPPPPPP---------PATAAPPPPP---------PPPPPPASAAAPASGPPA 104
+ PPPPPP P+TA P PPP PPPP P + P PP
Sbjct: 875 ------MVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPP---PPP 925
Query: 105 PPG---LAAGPGPAGGAPTPALVAGSSAAAPFP 134
PG L P P G P P + G++ P P
Sbjct: 926 LPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPP 958
Score = 58.2 bits (139), Expect = 3e-08
Identities = 52/153 (33%), Positives = 59/153 (38%), Gaps = 39/153 (25%)
Query: 5 PPPPPPQQQQQQQQLS----PPPPAALAPVSGVVL--PAPPAVSAGSSPAGSPGGGAGGE 58
PPPPPP L P PP P+ G + P PP + P P GAG
Sbjct: 877 PPPPPPLPGMTVPTLPSTAIPQPP----PLQGTEMLPPPPPPLPGAGIPPPPPLPGAG-- 930
Query: 59 GLGAAAAALLLHPPPPPPPATAAPPPP-PP---PPPPPASAAA-------PASG-PPAPP 106
+ P PP P A PPPP P PPPPP A P +G PP PP
Sbjct: 931 ----------ILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPP 980
Query: 107 GLAAG-----PGPAGGAPTPALVAGSSAAAPFP 134
AG P P G P P + G+ P P
Sbjct: 981 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1013
Score = 47.0 bits (110), Expect = 6e-05
Identities = 43/122 (35%), Positives = 49/122 (40%), Gaps = 14/122 (11%)
Query: 11 QQQQQQQQLS-----PPPPAALAPVSGVVLPAP-----PAVSAGSSPAGSPGGGAGGEGL 60
QQQQQQQQL PP A++P G L P+ AG +P GSP L
Sbjct: 218 QQQQQQQQLQGAEEPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAP-GSPDTEQALSAL 276
Query: 61 GAAAAALLLHP--PPPPPPATAAPPPPPPPPPPPASAAAPASGPPAPPGLAAGPG-PAGG 117
+L P P PP P P P AA + A P AGPG A G
Sbjct: 277 SDLPESLAAEPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAG 336
Query: 118 AP 119
AP
Sbjct: 337 AP 338
Score = 45.4 bits (106), Expect = 2e-04
Identities = 45/148 (30%), Positives = 54/148 (36%), Gaps = 15/148 (10%)
Query: 11 QQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAG---------SPGGGAGGEGLG 61
QQQQQQ QL + G PA P + P P GGA GE G
Sbjct: 207 QQQQQQLQLQLQQQQQQQQLQGAEEPAAPPTAVSPQPGAFLGLDRFLLGPSGGA-GEAPG 265
Query: 62 AAAAALLLHPPPPPPPATAAPPPPPPPPPPPASAAAPASGPPAPPGL--AAGPGPAGGA- 118
+ L P + AA P P PP P P S P+ P AA P+ A
Sbjct: 266 SPDTEQALSALSDLPESLAAEPREPQQPPSP--GGLPVSEAPSLPAAQPAAKDSPSSTAF 323
Query: 119 PTPALVAGSSAAAPFPHGDSALNEQEKE 146
P P G AA G +E+ +E
Sbjct: 324 PFPEAGPGEEAAGAPVRGAGDTDEEGEE 351
Score = 37.4 bits (85), Expect = 0.050
Identities = 43/159 (27%), Positives = 50/159 (31%), Gaps = 16/159 (10%)
Query: 4 QPPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGAA 63
QPP P + L PAA S P P A G AG+P GAG
Sbjct: 292 QPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEA-GPGEEAAGAPVRGAGDTDEEGE 350
Query: 64 AAALLLHPPPPP-----------PPATAAPPPPPPPPPPPASAAAPASGPPAPPGLAAGP 112
A P P P P P A AAA G PAP P
Sbjct: 351 EDAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPEEEAQGPDAPAAASLPGSPAPSQRCFKP 410
Query: 113 GPAGGAPTPALVAGSSAAAPFP-HGDSALNEQEKELQRR 150
P TP + ++ P H S Q ++RR
Sbjct: 411 YP---LITPCYIKTTTRQLSSPNHSPSQSPNQSPRIKRR 446
Score = 32.3 bits (72), Expect = 1.6
Identities = 22/79 (27%), Positives = 30/79 (37%), Gaps = 7/79 (8%)
Query: 32 GVVLPAPPAVSAGSSPAGSPGGGAGGEGLGAAAAALLLHP-------PPPPPPATAAPPP 84
G VL PP P PG +G + + +L++ P P + + PP
Sbjct: 752 GGVLTLPPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPP 811
Query: 85 PPPPPPPPASAAAPASGPP 103
PPP A P S PP
Sbjct: 812 PPPSLLWSAGQGQPGSQPP 830
>gi|56118221 amyloid beta (A4) precursor protein-binding, family B,
member 1 interacting protein [Homo sapiens]
Length = 666
Score = 73.6 bits (179), Expect = 6e-13
Identities = 45/113 (39%), Positives = 49/113 (43%), Gaps = 24/113 (21%)
Query: 6 PPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGAAAA 65
PPPPP +L PPPP + P V P PP+ + G AG E
Sbjct: 555 PPPPPPPPLDDPELPPPPPDFMEPPPDFVPPPPPSYA----------GIAGSE------- 597
Query: 66 ALLLHPPPPPPPATAAPPPPPPPPPPPASAAAPASGPPAPPGLAAGPGPAGGA 118
L PPPPPPPA A P P PPP A A PP PP PG GGA
Sbjct: 598 ---LPPPPPPPPAPAPAPVPDSARPPP----AVAKRPPVPPKRQENPGHPGGA 643
Score = 72.0 bits (175), Expect = 2e-12
Identities = 49/120 (40%), Positives = 52/120 (43%), Gaps = 21/120 (17%)
Query: 23 PPAALAPVSGVVLPAPPAVSAGSSPAGSPGG-----GAGGEGLGAAAAALLLHPPPPPPP 77
P A AP S LP PP V S +GSP G GG GL A L PPPPPP
Sbjct: 506 PRAPHAPKSS--LPPPPPVRRSSDTSGSPATPLKAKGTGGGGLPAPPDDFLPPPPPPPPL 563
Query: 78 ATAAPPPPPP----------PPPPPASAAAPAS----GPPAPPGLAAGPGPAGGAPTPAL 123
PPPPP PPPPP+ A S PP PP A P P P PA+
Sbjct: 564 DDPELPPPPPDFMEPPPDFVPPPPPSYAGIAGSELPPPPPPPPAPAPAPVPDSARPPPAV 623
Score = 39.3 bits (90), Expect = 0.013
Identities = 25/56 (44%), Positives = 27/56 (48%), Gaps = 2/56 (3%)
Query: 66 ALLLHPPPPPPPATAAPPPPPPPPPPPASAAAPASGPPAPPGLAAGPGPAGGAPTP 121
AL H P P A AP P PPPP ++ SG PA P A G G GG P P
Sbjct: 496 ALGNHHDPAVPRAPHAPKSSLP-PPPPVRRSSDTSGSPATPLKAKGTG-GGGLPAP 549
Score = 35.0 bits (79), Expect = 0.25
Identities = 17/43 (39%), Positives = 20/43 (46%), Gaps = 4/43 (9%)
Query: 52 GGGAGGEGLGAAAAALLLH----PPPPPPPATAAPPPPPPPPP 90
G + G G AA + + PPPP P P PPPPP P
Sbjct: 106 GAASLGYGTNVAATGISQYEDDLPPPPADPVLDLPLPPPPPEP 148
Score = 34.3 bits (77), Expect = 0.42
Identities = 24/65 (36%), Positives = 26/65 (40%), Gaps = 17/65 (26%)
Query: 1 MSGQPPPPPPQQQQQQQQLSPPPPA-ALAPVSGVVLPAPPAVSAGSSP------AGSPGG 53
++G PPPP PPPPA A APV P P P G PGG
Sbjct: 593 IAGSELPPPP----------PPPPAPAPAPVPDSARPPPAVAKRPPVPPKRQENPGHPGG 642
Query: 54 GAGGE 58
GGE
Sbjct: 643 AGGGE 647
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 73.2 bits (178), Expect = 8e-13
Identities = 49/140 (35%), Positives = 57/140 (40%), Gaps = 18/140 (12%)
Query: 5 PPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGAAA 64
PP P + +P PPAA P L PP A ++PA +P GG
Sbjct: 1087 PPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGG------- 1139
Query: 65 AALLLHPPPPPPPATAAPPPPPP-----PPPPPASAAAPASGPPAPPGLAAGPGPAGGAP 119
L PPP P T A PP P PPP + PA+ PP+P G A P P G
Sbjct: 1140 ---LATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPT 1196
Query: 120 TPALVAGS---SAAAPFPHG 136
TPA S A P P G
Sbjct: 1197 TPAATPPSPKGGLATPSPKG 1216
Score = 69.3 bits (168), Expect = 1e-11
Identities = 51/141 (36%), Positives = 57/141 (40%), Gaps = 14/141 (9%)
Query: 5 PPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGAAA 64
P P P+Q S P A A PAP + A SP G+P A
Sbjct: 900 PATPAPKQAPALSMTSSSPKKARAT------PAPKGIPASPSPKGAPTPPAATPPSPKGG 953
Query: 65 AALLLHPPPPPPPATAAPPPP--PPPPPPPASAAAPASGPPAPPGLAAGPGPAGGAPTPA 122
A P PPA P P P P P + PA+ PP+P G A P P GAPTP
Sbjct: 954 PATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPK-GAPTPP 1012
Query: 123 LVA-----GSSAAAPFPHGDS 138
V GS AA PFP G S
Sbjct: 1013 AVTPPSPKGSPAATPFPKGAS 1033
Score = 63.5 bits (153), Expect = 6e-10
Identities = 43/133 (32%), Positives = 51/133 (38%), Gaps = 15/133 (11%)
Query: 5 PPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGAAA 64
PP P + +P PAA P L PP A ++PA +P GG
Sbjct: 1133 PPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGG------- 1185
Query: 65 AALLLHPPPPPPPATAAPPPPPP-----PPPPPASAAAPASGPPAPPGLAAGPGPAGGAP 119
L P P P T A PP P P P + PA+ PP+P G A P P G
Sbjct: 1186 ---LATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPT 1242
Query: 120 TPALVAGSSAAAP 132
TPA S P
Sbjct: 1243 TPAATPPSPKGGP 1255
Score = 59.3 bits (142), Expect = 1e-08
Identities = 44/134 (32%), Positives = 55/134 (41%), Gaps = 15/134 (11%)
Query: 5 PPPPPPQQQQQQQQLSPPPPAAL--APVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGA 62
PP P + +P PPAA +P G P+P A + PA +P GG +
Sbjct: 947 PPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPK--GAPTPPAATPPSPKGGPATPS 1004
Query: 63 AAAALLLHPPPPPPPATAAPPP---PPPPPPPPASAAAPASGPPAPPGL-AAGPGPAGGA 118
A P PPA P P P P P ++ PA+ PP+P G AA P P G
Sbjct: 1005 PKGA-------PTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAP 1057
Query: 119 PTPALVAGSSAAAP 132
TPA S P
Sbjct: 1058 TTPAATLPSPKGGP 1071
Score = 58.9 bits (141), Expect = 2e-08
Identities = 48/145 (33%), Positives = 54/145 (37%), Gaps = 24/145 (16%)
Query: 5 PPPPPPQQQQQQQQLSPPPPAALAP--------VSGVVLPAPPAVSAGSSPAGSPGGGAG 56
PP P + +P PPAA P S P PPAV+ SP GSP
Sbjct: 970 PPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTP-PSPKGSPAATPF 1028
Query: 57 GEGLGAAAAALLLHPPPPPPPATAAPPPPPPPPPPPASAAAPASGPPAP-------PGLA 109
+G AA PP P A P P P P A+ +P GP P P A
Sbjct: 1029 PKGASTPPAAT---PPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAA 1085
Query: 110 AGPGPAGGAPTPALVAGSSAAAPFP 134
P P GG TP S AP P
Sbjct: 1086 TPPSPKGGPATP-----SPKGAPMP 1105
Score = 57.4 bits (137), Expect = 5e-08
Identities = 49/156 (31%), Positives = 57/156 (36%), Gaps = 28/156 (17%)
Query: 3 GQPPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGS----SPAGSPGGGAGGE 58
G P PPP+ +P PPAA P L PP A + +P GG A
Sbjct: 1253 GGPATPPPKG-------APTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSP 1305
Query: 59 GLGAAAAALLLHPPPP-----PPPATAAPPPPPPPPPPPASAAAPASGP-----PAPPGL 108
GA P P PPP A PP PP P + PA+ P P P
Sbjct: 1306 PKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSS 1365
Query: 109 AAGPGPAGGAPT----PALVAGS---SAAAPFPHGD 137
GP P P+ PA+ S A P P GD
Sbjct: 1366 KEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGD 1401
Score = 56.2 bits (134), Expect = 1e-07
Identities = 40/124 (32%), Positives = 48/124 (38%), Gaps = 9/124 (7%)
Query: 3 GQPPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGA 62
G P P + L+ PPP P+P A SP G+P A
Sbjct: 1147 GAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPA---ATPP 1203
Query: 63 AAAALLLHPPPPPPPATAAPPPPPP-----PPPPPASAAAPASGPPAPPGLAAGPGPAGG 117
+ L P P P T A PP P P P + PA+ PP+P G A P P G
Sbjct: 1204 SPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATP-PPKG 1262
Query: 118 APTP 121
APTP
Sbjct: 1263 APTP 1266
Score = 55.8 bits (133), Expect = 1e-07
Identities = 52/160 (32%), Positives = 60/160 (37%), Gaps = 25/160 (15%)
Query: 3 GQPPPP---PPQQQQQQQQLSP---PPPAALAPVSGVVLPA----------PPAVSAGSS 46
G P PP PP + SP P P A+ P S PA PPA + S
Sbjct: 984 GAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATP-PS 1042
Query: 47 PAGSPGGGAGGEGLGAAAAALLLHPPPPPPPATAAPPPPPPPPPPPASAAAPAS----GP 102
P GSP +G AA L P P + P PP PP+ PA+ G
Sbjct: 1043 PKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGA 1102
Query: 103 PAPPGLAAGPGPAGGAPTP---ALVAGSSAAAPFPHGDSA 139
P PP A P P GG TP +A P P G A
Sbjct: 1103 PMPPA-ATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLA 1141
Score = 55.8 bits (133), Expect = 1e-07
Identities = 43/136 (31%), Positives = 53/136 (38%), Gaps = 6/136 (4%)
Query: 5 PPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSP----GGGAGGEGL 60
PP P + +P PAA P PP A + PA +P GG A
Sbjct: 1225 PPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHK 1284
Query: 61 GAAAAALLLHPPPPPPPATAAPPPPPPPPPPPASAAAPASGPPAPPGLAAGPGPAGGAPT 120
GA A++ P P PAT+ PP P PP A+ +P P PP A PA P+
Sbjct: 1285 GAPNPAVVTPPSPKGGPATS--PPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPS 1342
Query: 121 PALVAGSSAAAPFPHG 136
P A P G
Sbjct: 1343 PKGTPTLPATTPSSKG 1358
Score = 55.1 bits (131), Expect = 2e-07
Identities = 53/164 (32%), Positives = 58/164 (35%), Gaps = 30/164 (18%)
Query: 3 GQPPPP---PPQQQQQQQQLSPP-----PPAALAPV-SGVVLPAPPAVSAGSSPAG---S 50
G P PP PP + P PPAA P G P A ++PA S
Sbjct: 1007 GAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPS 1066
Query: 51 PGGGAGGEGLGAAAAALLLHPPPPP-----PPATAAPPPPPPPPPPPASAAA-------- 97
P GG L A PP P P AP PP PP P A
Sbjct: 1067 PKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAP 1126
Query: 98 --PASGPPAPPGLAAGPGPAGGAPTPALVAGS---SAAAPFPHG 136
PA+ PP+P G A P P G TPA S A P P G
Sbjct: 1127 TTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKG 1170
Score = 54.3 bits (129), Expect = 4e-07
Identities = 43/135 (31%), Positives = 52/135 (38%), Gaps = 11/135 (8%)
Query: 5 PPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGAAA 64
PP P + +P PAA P L P A ++PA +P GG +
Sbjct: 1179 PPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPK 1238
Query: 65 AALLLHPPPPPPPATAAPPPPPPPPPPPASAAAPASGPPAPPGLAAGPGPAGGAPTPALV 124
A PP P PPP P P PA+ PP+ G A P P GAP PA+V
Sbjct: 1239 GAPTTPAATPPSPKGGPATPPPKGAPTP-----PAATPPSLKGGLATP-PHKGAPNPAVV 1292
Query: 125 AGSSAAAPFPHGDSA 139
P P G A
Sbjct: 1293 -----TPPSPKGGPA 1302
Score = 46.2 bits (108), Expect = 1e-04
Identities = 43/148 (29%), Positives = 52/148 (35%), Gaps = 15/148 (10%)
Query: 7 PPPPQQQQQQQQL---SPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGAA 63
PP P+ L +P PAA P P A + PA +P GG +
Sbjct: 1040 PPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSP 1099
Query: 64 AAALL--LHPPPPPPPATAAPPPPPPPPPPPASAAAPASG--PPAPPGL-----AAGPGP 114
A + PP P A PP P P A+ +P G P P G A P P
Sbjct: 1100 KGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSP 1159
Query: 115 AGGAPTP---ALVAGSSAAAPFPHGDSA 139
GG TP +A P P G A
Sbjct: 1160 KGGLATPPPKGAPTTPAATPPSPKGGLA 1187
Score = 44.7 bits (104), Expect = 3e-04
Identities = 33/119 (27%), Positives = 45/119 (37%), Gaps = 6/119 (5%)
Query: 19 LSPPPPAALAPVSGVV-----LPAPPAVSAGSSPAGSPGGGAGGEGLGAAAAALLLHPPP 73
LS PA LAP ++ +P+P A +P +P + E A +
Sbjct: 1534 LSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGA 1593
Query: 74 PPPPATAAPPPPPPPPPPPASAAAPASGPPAPPGLAAGPGPAGGAPTPALVAGSSAAAP 132
P P PP P P A PA PP+P A P P G +P + S +P
Sbjct: 1594 PSPKELLIPPAVTSPSPKEAPTP-PAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSP 1651
Score = 43.5 bits (101), Expect = 7e-04
Identities = 47/176 (26%), Positives = 61/176 (34%), Gaps = 14/176 (7%)
Query: 10 PQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSA--GSSPAGSPGGGAGGEGLGAAAAAL 67
P ++ L PP +P +P P A S A SP GA +
Sbjct: 1539 PATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKE 1598
Query: 68 LLHPPPPPPPATA-APPPPPPPPPPP---ASAAAPASGPPAPPGLAAGPGPAGGAPTPAL 123
LL PP P+ AP PP PP P + AP P +PP P +PT
Sbjct: 1599 LLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPP---VTPSSLKDSPTSPA 1655
Query: 124 VAGSSAAAPFPHGDSALNEQEKELQRRLKRLYPAVDEQETPL---PRSWSPKDKFS 176
A P L K+ LK + A + TP+ P P+ K S
Sbjct: 1656 SVTCKMGATVPQASKGL--PAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKS 1709
Score = 42.4 bits (98), Expect = 0.002
Identities = 35/112 (31%), Positives = 42/112 (37%), Gaps = 17/112 (15%)
Query: 39 PAVSAGSSPAGSPGGGAGGEGLGAAAAALLLHPPPPPPPATAAPPPPPPPPPPPASAAAP 98
PA + +P G + + L P P P+ P P P PA AP
Sbjct: 850 PATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAP 909
Query: 99 A-----SGP------PAPPGLAAGPGPAGGAPTPALVAGSSAAAPFPHGDSA 139
A S P PAP G+ A P P GAPTP +A P P G A
Sbjct: 910 ALSMTSSSPKKARATPAPKGIPASPSPK-GAPTP-----PAATPPSPKGGPA 955
Score = 42.4 bits (98), Expect = 0.002
Identities = 30/127 (23%), Positives = 40/127 (31%), Gaps = 15/127 (11%)
Query: 3 GQPPPPPPQQQQQQQQLSPPPPAALAPVSGVVL-----PAPPAVSAGSSPAGSPGGGAGG 57
G P PPP+ ++PP P + P P+ G +P + GG
Sbjct: 1322 GSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGG 1381
Query: 58 EGLGAAAAALLLHPPPPPPPATAAPPPPPPPPPPPASAAAPASGPPAPPGLAAGPGPAGG 117
+ PP P A P P P P +P P P P+ G
Sbjct: 1382 PAM----------TPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKG 1431
Query: 118 APTPALV 124
TP V
Sbjct: 1432 DLTPPAV 1438
Score = 42.0 bits (97), Expect = 0.002
Identities = 47/188 (25%), Positives = 64/188 (34%), Gaps = 26/188 (13%)
Query: 3 GQPPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAP------PAVSAGSSPAGSPGGGAG 56
G PP + ++PP +P G +P+P PAV SP +P
Sbjct: 1368 GPTPPAATPSHKGGPAMTPP-----SPKRGPAIPSPKGDPTSPAVIP-LSPKKAPATPVT 1421
Query: 57 GEGLGAAAAALLLHPPPPP-----PPATAAPPPPPPPPPPPASAAAPA------SGPPAP 105
EG + L P P PAT+AP P P PA PPAP
Sbjct: 1422 REGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAP 1481
Query: 106 PGLAAGPGPAGGAPTPALVAGSSAAAPFPHGDSALNEQEKELQRRLKRLYPAVDEQETPL 165
+A P TPA + + A P S+ E R + P
Sbjct: 1482 KQVATSSSPKKAPATPAPMGAPTLPAVIP---SSPKEVPATPSSRRDPIAPTATLLSKKT 1538
Query: 166 PRSWSPKD 173
P + +PK+
Sbjct: 1539 PATLAPKE 1546
Score = 42.0 bits (97), Expect = 0.002
Identities = 49/151 (32%), Positives = 55/151 (36%), Gaps = 27/151 (17%)
Query: 5 PPPP--PPQQQQQQQQLSPPP-PAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLG 61
PP P PP +Q SP PA AP+ LPA SSP P +
Sbjct: 1472 PPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAV----IPSSPKEVPATPSSRRDPI 1527
Query: 62 AAAAALL-------------LHPPP---PPPPATAAPPPPPPPPPPPASAAAPASGPPA- 104
A A LL L PP P P T A P P P P+S AS PPA
Sbjct: 1528 APTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSS--KEASSPPAV 1585
Query: 105 -PPGLAAGPGPAGGAPTPALVAGSSAAAPFP 134
P P P PA+ + S AP P
Sbjct: 1586 TPSTYKGAPSPKELLIPPAVTSPSPKEAPTP 1616
Score = 35.4 bits (80), Expect = 0.19
Identities = 34/123 (27%), Positives = 46/123 (37%), Gaps = 8/123 (6%)
Query: 5 PP--PPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAG--SPGGGAGGEGL 60
PP P P + + LS PA L PV A SP G +P L
Sbjct: 1714 PPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPL 1773
Query: 61 GAAAAALLLHPPPPPPPATAAPPPPPPPPPPPASAAAPASGPPAPPGLAAGPGPAGGAPT 120
AAA +L P P + + P PP P + + + PP L + PG +P+
Sbjct: 1774 TAAAFEKVL----PKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPS 1829
Query: 121 PAL 123
L
Sbjct: 1830 KPL 1832
Score = 30.8 bits (68), Expect = 4.7
Identities = 22/60 (36%), Positives = 26/60 (43%), Gaps = 7/60 (11%)
Query: 79 TAAPPPPPPPPPPPASAAAPASGPPAPPGLAAGPGPAGGAPTPALVAGSSAAAPFPHGDS 138
TAA P P PPP S A P P AA A P+P+ +A + PFP S
Sbjct: 35 TAALGQPGPTLPPPCSPA-----PQQCPLSAA--NQASPFPSPSTIASTPLEVPFPQSSS 87
Score = 30.8 bits (68), Expect = 4.7
Identities = 23/61 (37%), Positives = 29/61 (47%), Gaps = 5/61 (8%)
Query: 76 PPATAAPPPPPPPPPPPASAAAPASGPPAPPGLAAG----PGPAGGAPTPALVAGSSAAA 131
P T PP P P P SAA AS P+P +A+ P P + T AL G++ A
Sbjct: 41 PGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGT-ALPLGTAPEA 99
Query: 132 P 132
P
Sbjct: 100 P 100
Score = 30.8 bits (68), Expect = 4.7
Identities = 36/148 (24%), Positives = 48/148 (32%), Gaps = 35/148 (23%)
Query: 3 GQPPPP----PPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGE 58
G P P PP + +P PPA V P+P A +P G+
Sbjct: 1592 GAPSPKELLIPPAVTSPSPKEAPTPPA-------VTPPSPEKGPATPAPKGT-------- 1636
Query: 59 GLGAAAAALLLHPPPPPPPATAAPPPPPPPPPPPASAAAPASGPPAPPGLAAGPGPAGGA 118
P PP T + P P + A+ P A GL A GP A
Sbjct: 1637 --------------PTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPT--A 1680
Query: 119 PTPALVAGSSAAAPFPHGDSALNEQEKE 146
LVA + + P + Q K+
Sbjct: 1681 LKEVLVAPAPESTPIITAPTRKGPQTKK 1708
Score = 30.0 bits (66), Expect = 7.9
Identities = 31/118 (26%), Positives = 46/118 (38%), Gaps = 15/118 (12%)
Query: 19 LSPPPPAALAPVSGVVLPA--PPAVSAGS-SPAGSPGGGAGGEGLGAAAAALLLHPPPPP 75
++P P AP++ +VL P +V + S PAG+P G +G+ +A + P
Sbjct: 710 VAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKE 769
Query: 76 PP-------ATAAPPPP-----PPPPPPPASAAAPASGPPAPPGLAAGPGPAGGAPTP 121
P ATA+ P P S + PP G A P G +P
Sbjct: 770 CPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSP 827
>gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]
Length = 638
Score = 72.8 bits (177), Expect = 1e-12
Identities = 47/120 (39%), Positives = 56/120 (46%), Gaps = 16/120 (13%)
Query: 2 SGQPPPPP----PQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGG 57
SGQPPPPP P QQQQQQ PPPP + + S LP + ++ AG+
Sbjct: 486 SGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQ 545
Query: 58 EGLGAAAAAL---------LLHPPPP---PPPATAAPPPPPPPPPPPASAAAPASGPPAP 105
+ AAAA+ + P PP PP APPPPPPPPP A P G P
Sbjct: 546 QQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMIPPRGGDGP 605
Score = 59.7 bits (143), Expect = 9e-09
Identities = 49/154 (31%), Positives = 60/154 (38%), Gaps = 27/154 (17%)
Query: 7 PPPPQQQQQQQQLSPPPPAALAP-VSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGAAAA 65
PPPP Q PPPP P G P P GS+P GS G +G G
Sbjct: 420 PPPPWMQP------PPPPMNQGPHPPGHHGPPPMDQYLGSTPVGS-GVYRLHQGKGMMPP 472
Query: 66 ALLLHPPPPPPPATAAPPPPPP------------PPPPPASAAAPASGPPAP-------P 106
+ PPPPPP + PPPPP PPPPP +++ AS P P
Sbjct: 473 PPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTT 532
Query: 107 GLAAGPGPAGGAPTPALVAGSSAAAPFPHGDSAL 140
+AG G A +S AP G+ +
Sbjct: 533 TTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTM 566
Score = 48.5 bits (114), Expect = 2e-05
Identities = 55/212 (25%), Positives = 68/212 (32%), Gaps = 44/212 (20%)
Query: 4 QPPPPPPQQQQQQQQLSPPPPA----ALAPV-SGVV-------LPAPPAVSAGSSPAGSP 51
QPPPPP Q PPP PV SGV + PP + P P
Sbjct: 426 QPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPP 485
Query: 52 GGGAGGEGLGAAAA--ALLLHPPPPPPPATAAPPPPPPP-----------------PPPP 92
G G PPPPPPP+++ P P PP
Sbjct: 486 SGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQ 545
Query: 93 ASAAAPASGP------------PAPPGLAAGPGPAGGAPTPALVAGSSAAAPFPHGDSAL 140
AA A+ P P PPG+ P P P GS+ P G
Sbjct: 546 QQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMIPPRGGDGP 605
Query: 141 NEQEKELQRRLKRLYPAVDEQETPLPRSWSPK 172
+ + ++ R L L P Q+ P W K
Sbjct: 606 SHESEDFPRPLVTL-PGRQPQQRPWWTGWFGK 636
Score = 45.4 bits (106), Expect = 2e-04
Identities = 42/154 (27%), Positives = 53/154 (34%), Gaps = 61/154 (39%)
Query: 20 SPPPPAALAPVSGVVLPAPPAVSAGSSPA----GSPGGGAGGEGLGAAAAALLL------ 69
+PPPP+ ++ PP +++G S + G GGG GG G G + L
Sbjct: 352 NPPPPSLMSTTQS----RPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGG 407
Query: 70 --------HPPPPPPPATAAPPPP------------PPP--------------------- 88
+P PPPP PPPP PPP
Sbjct: 408 HGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGK 467
Query: 89 ---PPPPASAAAPASGPPAPPGLAAGPGPAGGAP 119
PPPP P PP PP P P+G P
Sbjct: 468 GMMPPPPMGMMPP---PPPPPSGQPPPPPSGPLP 498
Score = 34.3 bits (77), Expect = 0.42
Identities = 30/113 (26%), Positives = 43/113 (38%), Gaps = 15/113 (13%)
Query: 7 PPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGAAAAA 66
P PQ Q + ++ + +A + P P +V + S PA +P A AA
Sbjct: 297 PGDPQSAQDKARMDKEYLSLMAELGEA--PVPASVGSTSGPATTPLASA------PRPAA 348
Query: 67 LLLHPPPPPPPATAAPPPPPPPPPPPASAAAPASGPPAPPGLAAGPGPAGGAP 119
+PPPP +T PP + P+ P GPG GG P
Sbjct: 349 PANNPPPPSLMSTT-------QSRPPWMNSGPSESRPYHGMHGGGPGGPGGGP 394
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 71.6 bits (174), Expect = 2e-12
Identities = 52/126 (41%), Positives = 59/126 (46%), Gaps = 22/126 (17%)
Query: 24 PAALAPVS-----GVVLPAPPAVSAGSSPAGSPGGGAGGEGLGAAAAALLLHPPPPPPPA 78
PAAL P+ G V+ PP V A + PA + A AAA PPPPP PA
Sbjct: 222 PAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAA---PPPPPPAPA 278
Query: 79 TAAPPP-----PP---PPPPPPASA--AAPASGPPAPPGLAAGPGPAGGAPTPALVAGSS 128
T A PP PP P PPPA+A A PAP A GP G P P G++
Sbjct: 279 TLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGP----GAA 334
Query: 129 AAAPFP 134
AAAP P
Sbjct: 335 AAAPAP 340
Score = 68.6 bits (166), Expect = 2e-11
Identities = 45/120 (37%), Positives = 51/120 (42%), Gaps = 34/120 (28%)
Query: 20 SPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGAAAAALLLHPPPPPPPAT 79
+PP PAA P+PPA A ++PA +P PPPPP PAT
Sbjct: 248 APPAPAA---------PSPPAAPAPAAPAAAP-------------------PPPPPAPAT 279
Query: 80 AAPPPPPPPPPPPASAAAPASGPPAPPGLAAGPGPAGGAPTPALVAGSSAAAPFPHGDSA 139
A PP P PP A+ A P PP A G AG AP PA AG A G A
Sbjct: 280 LARPPGHPAGPPTAAPAVP------PPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGA 333
Score = 62.8 bits (151), Expect = 1e-09
Identities = 48/138 (34%), Positives = 59/138 (42%), Gaps = 20/138 (14%)
Query: 5 PPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAV----SAGSSP-----AGSPGGGA 55
PPPPPP + PP A P + +P P A SAG++P AG P G +
Sbjct: 270 PPPPPPAPATLAR---PPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVS 326
Query: 56 GGEGLGAAAAALLLHPPPPPPPATAAPPPPPPPPPPPASAAAPASGPPA-PPGLAAGPGP 114
G G GAAAAA P P A P PPA+ ASGP + + GP
Sbjct: 327 GQPGPGAAAAA-------PAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTM 379
Query: 115 AGGAPTPALVAGSSAAAP 132
G P+PA V + P
Sbjct: 380 QGALPSPAAVPPPAPGTP 397
Score = 54.7 bits (130), Expect = 3e-07
Identities = 46/133 (34%), Positives = 53/133 (39%), Gaps = 6/133 (4%)
Query: 3 GQPPPPPPQQQQQQQQLSPPPPAALAPVSGVVL--PAPPAVSAGSSPAGSPGGGAGGEGL 60
G P PPP + + P P +P +V PAPPA P GS G A +
Sbjct: 84 GAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAP---V 140
Query: 61 GAAAAALLLHPPPPPPPATAAPPPPPPPPPPPASAAAPASGPPAPPGLAAGPGPAGGA-P 119
AAAA P P PA A P P P GP PG AGPG A
Sbjct: 141 PAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNG 200
Query: 120 TPALVAGSSAAAP 132
+ AL+ AAAP
Sbjct: 201 SAALLNSHHAAAP 213
Score = 54.7 bits (130), Expect = 3e-07
Identities = 55/174 (31%), Positives = 66/174 (37%), Gaps = 44/174 (25%)
Query: 3 GQPPPPPPQQQQQQQQLSPPPPAA-LAPV----SGVVLPAPPAVSAGSSPAGSPGGGAGG 57
G P PP ++ P PPAA L P +G P P A + + P +P G A
Sbjct: 101 GPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPA-- 158
Query: 58 EGLGAAAAALLLHPPPPPPPATAAPPPPPPPPPPPAS--------------AAAPA---- 99
+ G AA A P P P P P P P P A+ AAAPA
Sbjct: 159 KPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLV 218
Query: 100 -SGPPA----------------PP--GLAAGPGPAGGAPTPALVAGSSAAAPFP 134
+GP A PP G AA P PA +P A + AAAP P
Sbjct: 219 NNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPP 272
Score = 53.5 bits (127), Expect = 7e-07
Identities = 42/117 (35%), Positives = 46/117 (39%), Gaps = 10/117 (8%)
Query: 27 LAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGAAAAALLLHPPPPPPPATAAP---P 83
LAP + V A +GSP G AG G A A P PPP A P
Sbjct: 43 LAPRTPEVRAAAAGALGNHVVSGSPAGAAGA-GPAAPAEGAPGAAPEPPPAGRARPGGGG 101
Query: 84 PPPPPPPPPASAAAPASGPPAPPGLAAGPGPAGG----APTPALVAGSSAAAPFPHG 136
P P PP P PA PAPP P P G AP PA A ++ P P G
Sbjct: 102 PQRPGPPSPRRPLVPAG--PAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAG 156
Score = 53.1 bits (126), Expect = 9e-07
Identities = 42/134 (31%), Positives = 53/134 (39%), Gaps = 18/134 (13%)
Query: 19 LSPPPPAALAPVSGV----VLPAPPAVSAGSSPA----GSPGGGA----GGEGLGAAAAA 66
L+P P A +G V+ PA +AG+ PA G+PG G
Sbjct: 43 LAPRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGP 102
Query: 67 LLLHPPPPPPPATAAPPPPPPPP--PPPASAAAPASGPPAPPGLAAGPGPAGGAPT---- 120
PP P P A P PP PPP +A + PA +AAGP PA P
Sbjct: 103 QRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAG 162
Query: 121 PALVAGSSAAAPFP 134
PA +A + P P
Sbjct: 163 PAALAARAGPGPGP 176
>gi|7706501 WW domain binding protein 11 [Homo sapiens]
Length = 641
Score = 71.2 bits (173), Expect = 3e-12
Identities = 49/133 (36%), Positives = 53/133 (39%), Gaps = 10/133 (7%)
Query: 5 PPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPG--GGAGGEGLGA 62
PP P Q Q + PPP P + P PP P G+P G GL
Sbjct: 393 PPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMPGLRG 452
Query: 63 AAAALLLHPPPPPPPATAAPPPPPPP---PPPPASAAAPASGPPAPPGLAAGPGPAGGAP 119
LL PP PPP PPP PPP P PP P PPAPPG+ P P G
Sbjct: 453 PLPRLL--PPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGI---PPPRPGMM 507
Query: 120 TPALVAGSSAAAP 132
P LV A P
Sbjct: 508 RPPLVPPLGPAPP 520
Score = 55.1 bits (131), Expect = 2e-07
Identities = 38/118 (32%), Positives = 45/118 (38%), Gaps = 4/118 (3%)
Query: 17 QQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGAAAAALLLHPPPPPP 76
QQ +PP + + +P PP + +P P G G G A PP P
Sbjct: 389 QQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMP 448
Query: 77 PATAAPPPPPPPPPPPASAAAPASGPPAPPGLAAGPGPAGGAPTPALVAGSSAAAPFP 134
P PP PPP P GP PPGL GP P G P P L + P P
Sbjct: 449 GLRGPLPRLLPPGPPPGRPPGPPPGP--PPGLPPGPPPRG--PPPRLPPPAPPGIPPP 502
Score = 52.0 bits (123), Expect = 2e-06
Identities = 46/151 (30%), Positives = 53/151 (35%), Gaps = 33/151 (21%)
Query: 3 GQPPPPPPQQQQQQQQLSPPPPAALAP------VSGVVLPAPPAVSAGSSPAGSPGGGAG 56
G PP PP + L P PP P + G+ P P + G P PG G
Sbjct: 414 GPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPG 473
Query: 57 GEGLGAAAAALLLHPP--PPPPPATAAPP--PPPPPP----PPPASAAAPASGP--PAPP 106
PP PP PP PP PPP PP P P P P PAPP
Sbjct: 474 P-------------PPGLPPGPPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPP 520
Query: 107 GLAAGPGPAGGAPTPALVAGSSAAAPFPHGD 137
GL P P P +++ P D
Sbjct: 521 GLF----PPAPLPNPGVLSAPPNLIQRPKAD 547
Score = 45.1 bits (105), Expect = 2e-04
Identities = 27/64 (42%), Positives = 30/64 (46%), Gaps = 7/64 (10%)
Query: 58 EGLGAAAAALLLHPPPPPPPATAAPPPPPPPP--PPPASAAAPASGPPAPPGLAAGPGPA 115
+G A++ P PP APP P PPP PPP AP PP PP PGP
Sbjct: 381 DGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPP----APPLRPPGPP-TGLPPGPP 435
Query: 116 GGAP 119
GAP
Sbjct: 436 PGAP 439
Score = 35.0 bits (79), Expect = 0.25
Identities = 26/85 (30%), Positives = 34/85 (40%), Gaps = 13/85 (15%)
Query: 13 QQQQQQLSPPPPAALAP----VSGVVLPA--PPAVSAGSSPAGSPGGGAGGEGLGAAAAA 66
Q + + P P AP + + LP PP++ +S G P +
Sbjct: 132 QHVEVESIPLPDMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPTRAV-------SILP 184
Query: 67 LLLHPPPPPPPATAAPPPPPPPPPP 91
LL H P PP P PPP PPPP
Sbjct: 185 LLGHGVPRLPPGRKPPGPPPGPPPP 209
Score = 32.7 bits (73), Expect = 1.2
Identities = 30/97 (30%), Positives = 36/97 (37%), Gaps = 11/97 (11%)
Query: 3 GQPPPPPPQQQQQQQQLSPP--PPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGL 60
G+PP PPP PP PP L P + +P PP P P L
Sbjct: 465 GRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIP-PPRPGMMRPPLVPP--------L 515
Query: 61 GAAAAALLLHPPPPPPPATAAPPPPPPPPPPPASAAA 97
G A L P P P +APP P ++AA
Sbjct: 516 GPAPPGLFPPAPLPNPGVLSAPPNLIQRPKADDTSAA 552
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 70.1 bits (170), Expect = 7e-12
Identities = 48/132 (36%), Positives = 50/132 (37%), Gaps = 14/132 (10%)
Query: 3 GQPPPPPPQQQQQQQQLSPPPPAALA--PVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGL 60
G PPP P Q + L PP P P G VLP P A P G+
Sbjct: 225 GPPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPF 284
Query: 61 GAAAAALLLHPPPPPPPATAAPPPPPPPPPPPASAAAPASGPPAPPGLAAG--------- 111
G L PP PPPP PPP PPPP P PP PPG
Sbjct: 285 GQPPLGPL--PPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPH 342
Query: 112 -PGPAGGAPTPA 122
PGP GAP PA
Sbjct: 343 LPGPPPGAPPPA 354
Score = 57.8 bits (138), Expect = 4e-08
Identities = 51/157 (32%), Positives = 55/157 (35%), Gaps = 30/157 (19%)
Query: 3 GQPPPPP---PQQQQQQQQLSPPPPAALAPVSGV-VLPAPPAVSAGSSPAGSPGGGAGGE 58
G PPPP P Q Q L P PP PV G P PP G P P
Sbjct: 270 GDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGP------- 322
Query: 59 GLGAAAAALLLHPPPPP----PPATAAPPPPPPPPPPPASAAAPASGPP--APPGLAAGP 112
PP PP PP T APPP P PPP A AP P PP + P
Sbjct: 323 -----------FPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMP 371
Query: 113 GPAGGAPTPALVAGSSAAAPFPHGDSALNEQEKELQR 149
P P G P+ GD +E + R
Sbjct: 372 TSDSRGPPPTDPYG--RPPPYDRGDYGPPGREMDTAR 406
Score = 56.6 bits (135), Expect = 8e-08
Identities = 46/142 (32%), Positives = 51/142 (35%), Gaps = 13/142 (9%)
Query: 1 MSGQPPPPPPQQQQ--QQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGE 58
+ GQ P P +Q Q ++ +SG PP GSS A P GG G
Sbjct: 149 LHGQNPVVTPCNKQFLSQFEMQSRKTTQSGQMSGEGKAGPPG---GSSRAAFPQGGRGRG 205
Query: 59 GLGAAAAALLLHP-------PPPPPPATAAPPPPP-PPPPPPASAAAPASGPPAPPGLAA 110
A P PPPP PA PP PP PP PP P G PP LA
Sbjct: 206 RFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAG 265
Query: 111 GPGPAGGAPTPALVAGSSAAAP 132
P P P L G P
Sbjct: 266 PPNRGDRPPPPVLFPGQPFGQP 287
Score = 43.1 bits (100), Expect = 0.001
Identities = 34/101 (33%), Positives = 38/101 (37%), Gaps = 16/101 (15%)
Query: 43 AGSSPAGSPGGGA------GGEGLGAAAAALLLHPPPPPPPATAAPPPPPPPPPPPASAA 96
+G AG PGG + GG G G A+ P P A P PPPP P +
Sbjct: 181 SGEGKAGPPGGSSRAAFPQGGRGRGRFPGAV---PGGDRFPGPAGPGGPPPPFPAGQT-- 235
Query: 97 APASGPPAPPGLAAGPGPAGGAPTPALVAGSSAAAPFPHGD 137
PP PP GP G P P V A P GD
Sbjct: 236 -----PPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGD 271
>gi|56549694 enabled homolog isoform a [Homo sapiens]
Length = 591
Score = 69.3 bits (168), Expect = 1e-11
Identities = 41/113 (36%), Positives = 46/113 (40%), Gaps = 33/113 (29%)
Query: 2 SGQPPPPPPQQQQQQQQLSPPPPAALAP---VSGVVLPAPPAVSAGSSPAGSPGGGAGGE 58
+ QP P QQ L+PPPP L P + V LP PP
Sbjct: 294 ASQPAETPSQQGIVLGPLAPPPPPPLPPGPAQASVALPPPPG------------------ 335
Query: 59 GLGAAAAALLLHPPPPPPPATAAPPPPPPPPPPPASAAAPASGPPAPPGLAAG 111
PPPPPP + PPPPPPPPP P P PPAPP A+G
Sbjct: 336 ------------PPPPPPLPSTGPPPPPPPPPLPNQVPPPPPPPPAPPLPASG 376
Score = 63.2 bits (152), Expect = 8e-10
Identities = 43/133 (32%), Positives = 57/133 (42%), Gaps = 24/133 (18%)
Query: 11 QQQQQQQQL----------SPPPPAALAPVSGVV---LPAPPAVSAGSSPAGSPGGGAGG 57
Q+Q +++QL + P + P++ V+ + P + A S PA +P
Sbjct: 248 QEQLEREQLEWERERRISSAAAPASVETPLNSVLGDSSASEPGLQAASQPAETPSQQ--- 304
Query: 58 EGLGAAAAALLLHPPPPPPP-----ATAAPPPPPPPPPPPASAAAPASGPPAPPGLAAGP 112
G L PPPP PP + A PPPP PPPPPP + P PP PP P
Sbjct: 305 ---GIVLGPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPPPPPPPLPNQVP 361
Query: 113 GPAGGAPTPALVA 125
P P P L A
Sbjct: 362 PPPPPPPAPPLPA 374
>gi|39930375 enabled homolog isoform b [Homo sapiens]
Length = 570
Score = 69.3 bits (168), Expect = 1e-11
Identities = 41/113 (36%), Positives = 46/113 (40%), Gaps = 33/113 (29%)
Query: 2 SGQPPPPPPQQQQQQQQLSPPPPAALAP---VSGVVLPAPPAVSAGSSPAGSPGGGAGGE 58
+ QP P QQ L+PPPP L P + V LP PP
Sbjct: 294 ASQPAETPSQQGIVLGPLAPPPPPPLPPGPAQASVALPPPPG------------------ 335
Query: 59 GLGAAAAALLLHPPPPPPPATAAPPPPPPPPPPPASAAAPASGPPAPPGLAAG 111
PPPPPP + PPPPPPPPP P P PPAPP A+G
Sbjct: 336 ------------PPPPPPLPSTGPPPPPPPPPLPNQVPPPPPPPPAPPLPASG 376
Score = 63.2 bits (152), Expect = 8e-10
Identities = 43/133 (32%), Positives = 57/133 (42%), Gaps = 24/133 (18%)
Query: 11 QQQQQQQQL----------SPPPPAALAPVSGVV---LPAPPAVSAGSSPAGSPGGGAGG 57
Q+Q +++QL + P + P++ V+ + P + A S PA +P
Sbjct: 248 QEQLEREQLEWERERRISSAAAPASVETPLNSVLGDSSASEPGLQAASQPAETPSQQ--- 304
Query: 58 EGLGAAAAALLLHPPPPPPP-----ATAAPPPPPPPPPPPASAAAPASGPPAPPGLAAGP 112
G L PPPP PP + A PPPP PPPPPP + P PP PP P
Sbjct: 305 ---GIVLGPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPPPPPPPLPNQVP 361
Query: 113 GPAGGAPTPALVA 125
P P P L A
Sbjct: 362 PPPPPPPAPPLPA 374
>gi|52485606 formin-like 2 [Homo sapiens]
Length = 1092
Score = 68.9 bits (167), Expect = 2e-11
Identities = 44/111 (39%), Positives = 54/111 (48%), Gaps = 22/111 (19%)
Query: 39 PAVSAGSSPAGSP--GGGAGGEGLGAAAAALLLHPPPPPPPATAAP------------PP 84
P V++G+ GS G + G +GAA++ L PPPP PP++ P PP
Sbjct: 495 PVVASGTLSMGSEVVAGNSVGPTMGAASSGPLPPPPPPLPPSSDTPETVQNGPVTPPMPP 554
Query: 85 PPPPPPPPASAAAPASGPPAPPGLAAGPGPAG-GAPTPALVAGSSAAAPFP 134
PPPPPPPP P PP PP L PGPA P P L +A P P
Sbjct: 555 PPPPPPPP----PPPPPPPPPPPL---PGPAAETVPAPPLAPPLPSAPPLP 598
Score = 67.0 bits (162), Expect = 6e-11
Identities = 43/127 (33%), Positives = 47/127 (37%), Gaps = 40/127 (31%)
Query: 5 PPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGAAA 64
PPPPPP L P +G V P P
Sbjct: 527 PPPPPP--------LPPSSDTPETVQNGPVTPPMP------------------------- 553
Query: 65 AALLLHPPPPPPPATAAPPPPPPPPPPPASAAAPASGPPAPPGLAAGPGPAGGAPTPALV 124
PPPPPPP PPPPPPPPP P AA PP P L + P P G +P +V
Sbjct: 554 ------PPPPPPPPPPPPPPPPPPPPLPGPAAETVPAPPLAPPLPSAP-PLPGTSSPTVV 606
Query: 125 AGSSAAA 131
S AA
Sbjct: 607 FNSGLAA 613
Score = 36.6 bits (83), Expect = 0.085
Identities = 22/68 (32%), Positives = 27/68 (39%), Gaps = 1/68 (1%)
Query: 5 PPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGAAA 64
PPPPPP PPPP P + V PAPP S PG + +
Sbjct: 553 PPPPPPPPPPPPPPPPPPPPPLPGPAAETV-PAPPLAPPLPSAPPLPGTSSPTVVFNSGL 611
Query: 65 AALLLHPP 72
AA+ + P
Sbjct: 612 AAVKIKKP 619
>gi|208431824 forkhead box I3 [Homo sapiens]
Length = 420
Score = 68.9 bits (167), Expect = 2e-11
Identities = 49/120 (40%), Positives = 50/120 (41%), Gaps = 10/120 (8%)
Query: 4 QPPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSP-AGSPGGGAGGEGLGA 62
QP PPP PPAA AP APPA +A PG G A
Sbjct: 14 QPGLPPPAATAAAPGA---PPAARAPYGLADYAAPPAAAANPYLWLNGPGVGGPPSAAAA 70
Query: 63 AAAALLLHPPPPPPPATAAPPPPPPPPPPPASA------AAPASGPPAPPGLAAGPGPAG 116
AAAA L PPPPPPP AA P PPP A PA PA P AGPG G
Sbjct: 71 AAAAYLGAPPPPPPPGAAAGPFLQPPPAAGTFGCSQRPFAQPAPAAPASPAAPAGPGELG 130
Score = 43.9 bits (102), Expect = 5e-04
Identities = 43/122 (35%), Positives = 51/122 (41%), Gaps = 33/122 (27%)
Query: 38 PPAVSAGSSPAGSPGGGAGGEGLGAAAAALLLHPPPPPPPATAAPP-----PPPPPPPPP 92
PP + ++P G+P GL AA PPA AA P P PP
Sbjct: 18 PPPAATAAAP-GAPPAARAPYGLADYAA----------PPAAAANPYLWLNGPGVGGPPS 66
Query: 93 ASAAAPAS-----GPPAPPGLAAG----PGPAGGA--------PTPALVAGSSAAAPFPH 135
A+AAA A+ PP PPG AAG P PA G PA A +S AAP
Sbjct: 67 AAAAAAAAYLGAPPPPPPPGAAAGPFLQPPPAAGTFGCSQRPFAQPAPAAPASPAAPAGP 126
Query: 136 GD 137
G+
Sbjct: 127 GE 128
Score = 36.6 bits (83), Expect = 0.085
Identities = 27/72 (37%), Positives = 31/72 (43%), Gaps = 1/72 (1%)
Query: 3 GQPPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGA 62
G PPPPPP L PPP A S A PA +A +SPA G G G A
Sbjct: 77 GAPPPPPPPGAAAGPFLQPPPAAGTFGCSQRPF-AQPAPAAPASPAAPAGPGELGWLSMA 135
Query: 63 AAAALLLHPPPP 74
+ L+ PP
Sbjct: 136 SREDLMKMVRPP 147
>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
preproprotein [Homo sapiens]
Length = 331
Score = 68.9 bits (167), Expect = 2e-11
Identities = 48/151 (31%), Positives = 55/151 (36%), Gaps = 22/151 (14%)
Query: 3 GQPPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGA 62
G+P PPPQ + + SPP P G P P G P GG +G
Sbjct: 75 GKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQG--- 131
Query: 63 AAAALLLHPPPP-----PPPA-----TAAPPPPPPPPPPPASAAAPASGPPAPPGLAAGP 112
PPPP PPP + PP P PPP P GPP PPG GP
Sbjct: 132 --------PPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQP-QGPPPPPGKPQGP 182
Query: 113 GPAGGAPTPALVAGSSAAAPFPHGDSALNEQ 143
P GG P P GD + + Q
Sbjct: 183 PPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQ 213
Score = 65.1 bits (157), Expect = 2e-10
Identities = 43/125 (34%), Positives = 49/125 (39%), Gaps = 22/125 (17%)
Query: 3 GQPPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGA 62
G+P PPPQ + + SPP P G P P G P GG +G
Sbjct: 136 GKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQG--- 192
Query: 63 AAAALLLHPPPP-----PPPA-----TAAPPPPPPPPPPPASAAAPASGPPAPPGLAAGP 112
PPPP PPP ++ PP P PPP P GPP PPG GP
Sbjct: 193 --------PPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQP-QGPPPPPGKPQGP 243
Query: 113 GPAGG 117
P GG
Sbjct: 244 PPQGG 248
Score = 59.3 bits (142), Expect = 1e-08
Identities = 50/147 (34%), Positives = 52/147 (35%), Gaps = 28/147 (19%)
Query: 3 GQPPPPPPQQQQQQQQLSPPP--PAALAPVSG--VVLPAPPAVSAGSSPAG-------SP 51
G+P PPPQ Q Q PPP P P G P PP G P G SP
Sbjct: 95 GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSP 154
Query: 52 GGGAGGEGLGAAAAALLLHPPPPPPPATAAPPPPPPPP--PPPASAAAPASGPPAPPGLA 109
G G PPP PPPPP P PPP P GPP PPG
Sbjct: 155 PGKPQG-------------PPPQGGNQPQGPPPPPGKPQGPPPQGGKKP-QGPP-PPGKP 199
Query: 110 AGPGPAGGAPTPALVAGSSAAAPFPHG 136
GP P G + P P G
Sbjct: 200 QGPPPQGDKSRSSQSPPGKPQGPPPQG 226
Score = 57.8 bits (138), Expect = 4e-08
Identities = 44/123 (35%), Positives = 49/123 (39%), Gaps = 16/123 (13%)
Query: 3 GQPPPPPPQQQQQQQQLSPPP--PAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGL 60
G+P PPPQ Q Q PPP P P G PP P G P G
Sbjct: 156 GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPP-------PPGKPQGPPPQGDK 208
Query: 61 GAAAAALLLHPPPPPPPA---TAAPPPPPPPP--PPPASAAAPASGPPAPPGLAAGPGPA 115
++ + P PPP PPPPP P PPP P GPP PPG GP
Sbjct: 209 SRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKP-QGPP-PPGKPQGPPAQ 266
Query: 116 GGA 118
GG+
Sbjct: 267 GGS 269
Score = 53.5 bits (127), Expect = 7e-07
Identities = 44/148 (29%), Positives = 49/148 (33%), Gaps = 26/148 (17%)
Query: 1 MSGQPPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGL 60
++G P P PQ + Q PPPP P P G+ P G P G+
Sbjct: 32 IAGNPQGPSPQGGNKPQ--GPPPPPGK--------PQGPPPQGGNKPQGPP---PPGKPQ 78
Query: 61 GAAAAALLLHPPPPPPPATAAPPP-----PPPPPPPPASAAAP-------ASGPPAPPGL 108
G P PP PPP P PPPPP P GPP PPG
Sbjct: 79 GPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPP-PPGK 137
Query: 109 AAGPGPAGGAPTPALVAGSSAAAPFPHG 136
GP P G P P G
Sbjct: 138 PQGPPPQGDKSRSPRSPPGKPQGPPPQG 165
Score = 53.1 bits (126), Expect = 9e-07
Identities = 39/115 (33%), Positives = 43/115 (37%), Gaps = 21/115 (18%)
Query: 3 GQPPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGA--GGEGL 60
G+P PPPQ Q Q PPPP P P G+ P G P G G
Sbjct: 217 GKPQGPPPQGGNQPQ--GPPPPPGK--------PQGPPPQGGNKPQGPPPPGKPQGPPAQ 266
Query: 61 GAAAAALLLHPPPPP--PPATAAPPPPPPPPP-------PPASAAAPASGPPAPP 106
G + + PP P PP P PPPP P A A GPP PP
Sbjct: 267 GGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPP 321
Score = 50.1 bits (118), Expect = 7e-06
Identities = 40/133 (30%), Positives = 45/133 (33%), Gaps = 45/133 (33%)
Query: 39 PAVSAGSSPAGSPGGGAGGEGLGAAAAALLLHPPPPPPPATAAPPP--------PPPP-- 88
P++ AG+ SP GG +G PPPPP PPP PPPP
Sbjct: 29 PSLIAGNPQGPSPQGGNKPQG------------PPPPPGKPQGPPPQGGNKPQGPPPPGK 76
Query: 89 P----------------------PPPASAAAPASGPPAPPGLAAGPGPAGGAPTPALVAG 126
P PPP P GPP PPG GP P GG
Sbjct: 77 PQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQP-QGPPPPPGKPQGPPPQGGNRPQGPPPP 135
Query: 127 SSAAAPFPHGDSA 139
P P GD +
Sbjct: 136 GKPQGPPPQGDKS 148
Score = 45.1 bits (105), Expect = 2e-04
Identities = 34/110 (30%), Positives = 37/110 (33%), Gaps = 24/110 (21%)
Query: 3 GQPPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGS------SPAGSPGGGAG 56
G+P PPPQ + Q PPPP P P GS SP G P G
Sbjct: 238 GKPQGPPPQGGNKPQ--GPPPPGK---------PQGPPAQGGSKSQSARSPPGKPQGPPQ 286
Query: 57 GEGLGAAAAALLLHPPPPPPPATAAPPPPPPPPPPPASAAAPASGPPAPP 106
EG PPPP P PP P P G P+ P
Sbjct: 287 QEGNNPQG-------PPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRP 329
Score = 30.8 bits (68), Expect = 4.7
Identities = 27/88 (30%), Positives = 29/88 (32%), Gaps = 33/88 (37%)
Query: 2 SGQPPPPPPQ---QQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGE 58
S + PP PQ QQ+ PPPPA P P P PAG P G
Sbjct: 273 SARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQ----PQAP-------PAGQPQG----- 316
Query: 59 GLGAAAAALLLHPPPPPPPATAAPPPPP 86
PP PP P PP
Sbjct: 317 --------------PPRPPQGGRPSRPP 330
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 68.6 bits (166), Expect = 2e-11
Identities = 39/102 (38%), Positives = 44/102 (43%), Gaps = 24/102 (23%)
Query: 4 QPPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGAA 63
+PPP PP Q Q PPPP LP+PP + A + + P
Sbjct: 1456 KPPPTPPPAPTPQPQPPPPPPPPQP-----ALPSPPPLVAPTPSSPPP------------ 1498
Query: 64 AAALLLHPPPPPPPATAAPPPPPPPPPPPASAAAPASGPPAP 105
PP PPPP A P PPPPPPP A AAP P AP
Sbjct: 1499 -------PPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAP 1533
Score = 64.7 bits (156), Expect = 3e-10
Identities = 38/114 (33%), Positives = 43/114 (37%), Gaps = 11/114 (9%)
Query: 21 PPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGAAAAALLLHPPPPPPPATA 80
PPP L + P PP + P P A PPPPPPP A
Sbjct: 1433 PPPLPGLPSANSNGTPEPPLLEEKPPPTPPP-----------APTPQPQPPPPPPPPQPA 1481
Query: 81 APPPPPPPPPPPASAAAPASGPPAPPGLAAGPGPAGGAPTPALVAGSSAAAPFP 134
P PPP P P+S P PP PP + + P P A P AAP P
Sbjct: 1482 LPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSP 1535
Score = 59.3 bits (142), Expect = 1e-08
Identities = 41/134 (30%), Positives = 49/134 (36%), Gaps = 10/134 (7%)
Query: 23 PPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGAAAAALLLHPPPPPPPATAAP 82
PP A P PP A + P P G LL PPP P A
Sbjct: 1408 PPLA-GPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPT 1466
Query: 83 PPPPPPPPP---------PASAAAPASGPPAPPGLAAGPGPAGGAPTPALVAGSSAAAPF 133
P P PPPPP P AP P PP L P PA +P P ++ A
Sbjct: 1467 PQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAP 1526
Query: 134 PHGDSALNEQEKEL 147
P +A + ++ EL
Sbjct: 1527 PEEPAAPSPEDPEL 1540
Score = 53.1 bits (126), Expect = 9e-07
Identities = 57/203 (28%), Positives = 69/203 (33%), Gaps = 64/203 (31%)
Query: 5 PPPPPPQQQQQQQQLSPPPPAALAPVSG----VVLPAPPAVSAGS----SPAGSPGGGAG 56
PPPPPP Q Q P P L G +VLP PP S +P+ SP
Sbjct: 764 PPPPPPTAQSTQ----PTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKV 819
Query: 57 GEGLGAAAAALLLHPPPPPPPATAAPPPPPPP-------------PPPPASAAAPASG-- 101
G L A PPPPPP PPPPP P P P+ P
Sbjct: 820 GVHLLEPATRDGAPQPPPPPP----PPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLD 875
Query: 102 ---------------PPAPPGLAAGP------GPAG--------GAPTPALVAGSSAAAP 132
PPAP GP PAG G P V +S P
Sbjct: 876 PPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSICFP 935
Query: 133 FPHGDSALNEQEKELQRRLKRLY 155
DS L ++E+ ++ ++
Sbjct: 936 ----DSLLQDEERSFFPTMEEMF 954
Score = 52.0 bits (123), Expect = 2e-06
Identities = 35/105 (33%), Positives = 46/105 (43%), Gaps = 7/105 (6%)
Query: 3 GQPPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGA 62
G+ PP + + PP P A P P P ++G+ P +PG G
Sbjct: 963 GKAGPPEDEGDPKAGAGPPPGPPAYDPYG----PYCPGRASGAGPE-TPGLGLDPNKPPE 1017
Query: 63 AAAALLLHPPP--PPPPATAAPPPPPPPPPPPASAAAPASGPPAP 105
+ + P P AAPPPPPPPPPPPA A+ P G +P
Sbjct: 1018 LPSTVNAEPLGLIQSGPHQAAPPPPPPPPPPPAPASEPKGGLTSP 1062
Score = 49.3 bits (116), Expect = 1e-05
Identities = 49/162 (30%), Positives = 53/162 (32%), Gaps = 46/162 (28%)
Query: 2 SGQPPPPPPQQQQQQQQLS----------------------PPPPAALAPVSGVVLPAPP 39
S QPPPPPP Q LS P P A P P
Sbjct: 297 SAQPPPPPPPAHALQHYLSCGGSYPSMGHRANLACSPLGGGEPSPGAGEPSKA----GPS 352
Query: 40 AVSAGSS-----PAGSPGGGAGG---------------EGLGAAAAALLLHPPPPPPPAT 79
+AG+S P + GGGAGG G G AA PPPP +T
Sbjct: 353 GATAGASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKGGYGAAAGGATRPPPPRST 412
Query: 80 AAPPPPPPPPPPPASAAAPASGPPAPPGLAAGPGPAGGAPTP 121
A P P A A ASG G A PG G P
Sbjct: 413 ATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQPQGLLGP 454
Score = 48.5 bits (114), Expect = 2e-05
Identities = 43/127 (33%), Positives = 48/127 (37%), Gaps = 15/127 (11%)
Query: 4 QPPPPPPQQQQQQQQLSPPPPA-ALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGA 62
+PPPP + Q L P A A SG A S G P G G A G+G G
Sbjct: 405 RPPPPRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQ-PQGLLGPQAYGQGFGG 463
Query: 63 AAAALLLHPPPPPPPATAAPPPPPPPPPPPASAAAPASGPPAPPGLAAG------PGPAG 116
A L P + PP PP PPPP A + P G G PGPA
Sbjct: 464 GQAQDL----SKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEPYPGPAA 519
Query: 117 ---GAPT 120
G PT
Sbjct: 520 HSQGLPT 526
Score = 47.8 bits (112), Expect = 4e-05
Identities = 48/133 (36%), Positives = 52/133 (39%), Gaps = 23/133 (17%)
Query: 4 QPP--PPPP--------QQQQQQQQL----SPPPPAALAPVSGVVLPAPP-AVSAGSSPA 48
QPP PPPP Q Q QL P P A G+ +P + S G SPA
Sbjct: 481 QPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGLPTASPSLSYSTGHSPA 540
Query: 49 GSP-GGGAGGEGLGAAAAALLLH--PPPPPPPATAAPPPPPPPPPP-----PASAAAPAS 100
S GGG G LG A H P PPAT PP P P A+AP
Sbjct: 541 LSGHGGGWGPSSLGGGGEASPSHIIRPLQSPPATGRPPGVGSPGAPGKYLSSVLASAPFL 600
Query: 101 GPPAPPGLAAGPG 113
PP AAG G
Sbjct: 601 APPGAGSYAAGAG 613
Score = 45.8 bits (107), Expect = 1e-04
Identities = 40/129 (31%), Positives = 49/129 (37%), Gaps = 21/129 (16%)
Query: 4 QPPPPPPQQQQQQQQLSPPPPAALAPVSGVVLP---APPAVSAGSSPAGSPGGGAGGEGL 60
+P P P Q SPP L+P + L AP S+ + GG G GL
Sbjct: 160 RPFPVPSSLSLQDPPFSPPANGLLSPHDVLHLKPSQAPTVPSSLGFERLAGGGVLGPAGL 219
Query: 61 GAAAAALLLHPPPPPPPATAAPPPPPPPPPP--------PASAAAPASGPPAPPGLAAGP 112
G P PP PP PPPPP +S+AA A+ + P L
Sbjct: 220 G----------PAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFS 269
Query: 113 GPAGGAPTP 121
G A G P P
Sbjct: 270 GAAPGPPPP 278
Score = 41.6 bits (96), Expect = 0.003
Identities = 43/153 (28%), Positives = 56/153 (36%), Gaps = 47/153 (30%)
Query: 4 QPPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGAA 63
+P PP P PPPP L P + A SS A + + + +
Sbjct: 228 RPGPPDP----------PPPPRHL--------PTQFNLLASSSAAAAAAEQSSPQLYNFS 269
Query: 64 AAALLLHPPPPPP----------------PATAAPPPPPPPPPP-----PASAAAPASGP 102
AA P PPPP PA+A PPPPPPP + P+ G
Sbjct: 270 GAA----PGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGH 325
Query: 103 PA----PPGLAAGPGPAGGAPTPALVAGSSAAA 131
A P P P G P+ A +G++A A
Sbjct: 326 RANLACSPLGGGEPSPGAGEPSKAGPSGATAGA 358
Score = 40.8 bits (94), Expect = 0.005
Identities = 50/175 (28%), Positives = 59/175 (33%), Gaps = 64/175 (36%)
Query: 8 PPPQQQQQQQQLSPP---PPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGG------- 57
PP Q LSPP PP+ P G+ P PPA A P S G GG
Sbjct: 1296 PPLYQAGLTPPLSPPKSVPPSV--PARGLQ-PQPPATPAVPHPPPSGAFGLGGALEAAES 1352
Query: 58 EGLG------------------------------------------AAAAALLLHPPPPP 75
EGLG ++A + L PP
Sbjct: 1353 EGLGLGCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAG 1412
Query: 76 PPATAAPPPP--------PPPPPPPASAAAPASGPPAPPGLAAGPGPA-GGAPTP 121
P T+ P P P PPP P +A ++G P PP L P P APTP
Sbjct: 1413 PKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTP 1467
Score = 39.7 bits (91), Expect = 0.010
Identities = 30/91 (32%), Positives = 34/91 (37%), Gaps = 28/91 (30%)
Query: 54 GAGGEGLGAAAAALLLHPPPPPPPATAAPPPPPP----------------PPPPPASAAA 97
GAG + LGA L PPPPP TA P P PPPPP +
Sbjct: 750 GAGAKELGA-----FLQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPS 804
Query: 98 PASGPPAPPGLAA-------GPGPAGGAPTP 121
S P+P A+ P GAP P
Sbjct: 805 VLSHAPSPSPSASKVGVHLLEPATRDGAPQP 835
Score = 35.0 bits (79), Expect = 0.25
Identities = 32/117 (27%), Positives = 45/117 (38%), Gaps = 22/117 (18%)
Query: 70 HPP-------PPPPPATAAPPPPPP---PPPPPASAAAPASGPPAPPGLAAGPGPAGGAP 119
HPP PP P + PP P P PPA+ A P P GL GGA
Sbjct: 1295 HPPLYQAGLTPPLSPPKSVPPSVPARGLQPQPPATPAVPHPPPSGAFGL-------GGAL 1347
Query: 120 TPALVAGSSAAAPFPHGDSALNEQEKELQRRLKRLYPAVDEQETPLPRSWSPKDKFS 176
A G P P ++EL+R L+ L ++E + ++ ++ S
Sbjct: 1348 EAAESEGLGLGCPSP-----CKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESIS 1399
Score = 35.0 bits (79), Expect = 0.25
Identities = 20/43 (46%), Positives = 20/43 (46%), Gaps = 9/43 (20%)
Query: 5 PPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSP 47
PPPPPP PPPP A AP L APP A SP
Sbjct: 1502 PPPPPPAMPSPP----PPPPPAAAP-----LAAPPEEPAAPSP 1535
Score = 33.5 bits (75), Expect = 0.72
Identities = 55/199 (27%), Positives = 63/199 (31%), Gaps = 50/199 (25%)
Query: 5 PPPPPPQQQQQQQQLSP--------PPPAALAPVSGVV-----LPAPPAVSAGSSPAGSP 51
P P P Q SP P P L +SG + P+ A+SA PA
Sbjct: 100 PQPGPSASSLLSQFRSPSWQTAMHTPGPTELF-ISGALPGSSTFPSSSALSAYQHPASF- 157
Query: 52 GGGAGGEGLGAAAAALLLHPPPPPPPATAAPPP-------PPPPPPPPASAA-------- 96
G ++L L PP PPA P P P P+S
Sbjct: 158 -----GSRPFPVPSSLSLQDPPFSPPANGLLSPHDVLHLKPSQAPTVPSSLGFERLAGGG 212
Query: 97 -------APASGPPAPPGLAAGPGPAGGAPTP-ALVAGSSAAAPFPHGDSALNEQEKELQ 148
PA PP PG P P PT L+A SSAAA A EQ
Sbjct: 213 VLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAA-------AAAEQSSPQL 265
Query: 149 RRLKRLYPAVDEQETPLPR 167
P E LPR
Sbjct: 266 YNFSGAAPGPPPPERALPR 284
Score = 32.0 bits (71), Expect = 2.1
Identities = 35/148 (23%), Positives = 50/148 (33%), Gaps = 35/148 (23%)
Query: 2 SGQPPP----PPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPA----------------- 40
S PPP PPP+ + ++ S PP + +P PPA
Sbjct: 1689 SSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETA---MPEPPAPEKPSLLRPVEKEKEKE 1745
Query: 41 -VSAGSSPAGSPGGGAGGE-------GLGAAAAALLLHPPPPPPPATAAPPPPPPPPPPP 92
V+ G P +G + G A + L P P A PPP
Sbjct: 1746 KVTRGERPLRGERATSGRQTRPERSLATGQPATSRL---PKARPTKVKAEPPPKKRKKWL 1802
Query: 93 ASAAAPASGPPAPPGLAAGPGPAGGAPT 120
A A+ PPG ++ + GAP+
Sbjct: 1803 KEAGGNATAGGGPPGSSSDSESSPGAPS 1830
Score = 31.6 bits (70), Expect = 2.7
Identities = 36/117 (30%), Positives = 42/117 (35%), Gaps = 18/117 (15%)
Query: 20 SPP----PPAALAP------VSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGAAAAALLL 69
SPP PP +P +S V+ AP G AGS GAGG + LL
Sbjct: 570 SPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPG---AGSYAAGAGGYKGKGDGSELLA 626
Query: 70 HPPPPPPPATAAPP-----PPPPPPPPPASAAAPASGPPAPPGLAAGPGPAGGAPTP 121
P PP T P PP S A G + G G +GGA P
Sbjct: 627 GPGGPPAERTEDEEFLIQHLLQAPSPPRTSGADGLVGEDGAADASKGLGGSGGAGGP 683
>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
Length = 1682
Score = 67.8 bits (164), Expect = 3e-11
Identities = 47/134 (35%), Positives = 55/134 (41%), Gaps = 19/134 (14%)
Query: 8 PPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGAAAAAL 67
PP ++ + + P PPAAL+ SG G SP G G E G
Sbjct: 195 PPVKRAAEPPVVQPVPPAALSGPSG---------EEGLSPGGKRRRGCNSEQTGLPPGLP 245
Query: 68 LLHPPPPPPPATAAPPPPPPPPPPPASAAAPASGPPAP------PGLAAGPGPAGGAPTP 121
L PP PPPP PPPPPPPPP P A +P P G A GP G AP
Sbjct: 246 LPPPPLPPPP----PPPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPE 301
Query: 122 ALVAGSSAAAPFPH 135
S P+P+
Sbjct: 302 RQEQRHSLPHPYPY 315
Score = 48.9 bits (115), Expect = 2e-05
Identities = 45/163 (27%), Positives = 61/163 (37%), Gaps = 39/163 (23%)
Query: 11 QQQQQQQQLSPPPPAALAPVSGVVLPAP---------PAVSAGSSPAGSPGGGAGGEGLG 61
+QQQ + ++P PP P + + P P PAV+ ++ + A E
Sbjct: 711 EQQQHEAGVAPQPPLK-EPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEK 769
Query: 62 AAAAALLLHPPPPPPPATAAPPPPPPPPPPP-----------------------ASAAAP 98
AL PPPPP A PP P PPPPP + AA
Sbjct: 770 KPPPAL----PPPPPLAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAV 825
Query: 99 ASGPPAPPGLAAGPGPAGGAPT--PALVAGSSAAAPFPHGDSA 139
++ P P PGP GA P A S+ +P P S+
Sbjct: 826 STRPGPLPTTQYSPGPPSGATALPPTSAAPSAQGSPQPSASSS 868
Score = 47.4 bits (111), Expect = 5e-05
Identities = 45/168 (26%), Positives = 63/168 (37%), Gaps = 11/168 (6%)
Query: 5 PPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGAAA 64
PPPPP + Q PPPP +P S +L + +V G G A G
Sbjct: 776 PPPPPLAKFPPPSQPQPPPPPPPSPAS--LLKSLASVLEGQKYCYRGTGAAVSTRPGPLP 833
Query: 65 AALLLHPPPPPPPATAAPPPPPPP-----PPPPASAAAP--ASGPPAPPGLAAGPGPAGG 117
+ P PP ATA PP P P P AS+++ SG P AG P G
Sbjct: 834 TTQ--YSPGPPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPG 891
Query: 118 APTPALVAGSSAAAPFPHGDSALNEQEKELQRRLKRLYPAVDEQETPL 165
TP + P L E + + ++R+ + + P+
Sbjct: 892 PMTPTQPPPPLSLPPARSESEVLEEISRACETLVERVGRSATDPADPV 939
Score = 44.3 bits (103), Expect = 4e-04
Identities = 39/119 (32%), Positives = 47/119 (39%), Gaps = 23/119 (19%)
Query: 3 GQPPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGA 62
G P PPPP PPPP P+ G+ P ++ + G G E G+
Sbjct: 243 GLPLPPPPLPPPP-----PPPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGS 297
Query: 63 AAAA------LLLHPPPPPPPA-TAAPP--------PPPPPPPPPAS---AAAPASGPP 103
A L HP P P PA TA PP PP P P PP + PA+ PP
Sbjct: 298 APPERQEQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPP 356
Score = 42.0 bits (97), Expect = 0.002
Identities = 34/113 (30%), Positives = 45/113 (39%), Gaps = 13/113 (11%)
Query: 3 GQPPPPPPQQQQQQQQLSPPPPA-ALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLG 61
G P P PP ++ L PP ++ P PP + SS + S G
Sbjct: 510 GPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNS--------GSH 561
Query: 62 AAAAALLLHPPPPPPPATAAPPPPPPPPPPPASAAAPASGPPAPPGLAAGPGP 114
+++ A + PPPP A + P P PP P A P P P LA P P
Sbjct: 562 SSSPAGPVSFPPPPYLARSIDPLPRPPSP----AQNPQDPPLVPLTLALPPAP 610
Score = 40.0 bits (92), Expect = 0.008
Identities = 39/129 (30%), Positives = 48/129 (37%), Gaps = 37/129 (28%)
Query: 7 PPPPQQQQQQQQLSPPPPAA-------LAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEG 59
PPPP + L PP A L P++ + PAPP+ S + +GS
Sbjct: 572 PPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALPPAPPS-SCHQNTSGS--------- 621
Query: 60 LGAAAAALLLHPPPPPPPATAAPPPP---PPPPPPPASAAAPASGPPAPPGL----AAGP 112
P P P + P P P PPP P S A P PPG+ A GP
Sbjct: 622 ---------FRRPESPRPRVSFPKTPEVGPGPPPGPLSKAP----QPVPPGVGELPARGP 668
Query: 113 GPAGGAPTP 121
PTP
Sbjct: 669 RLFDFPPTP 677
Score = 38.5 bits (88), Expect = 0.022
Identities = 21/51 (41%), Positives = 21/51 (41%)
Query: 71 PPPPPPPATAAPPPPPPPPPPPASAAAPASGPPAPPGLAAGPGPAGGAPTP 121
PPPPP P PPPPP PA AA G GP AP P
Sbjct: 468 PPPPPCPRLLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPP 518
Score = 35.0 bits (79), Expect = 0.25
Identities = 30/127 (23%), Positives = 39/127 (30%), Gaps = 28/127 (22%)
Query: 11 QQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGE------------ 58
Q+ + +SP A P + P P + SS + S G G
Sbjct: 366 QRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHY 425
Query: 59 -------------GLGAAAAALLLHPPPPPPPATAAPPPPPPPPPPPASAAAPASGPPAP 105
G A ++ P P + PP P PPPPP PP P
Sbjct: 426 QTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLL---RPPPP 482
Query: 106 PGLAAGP 112
P GP
Sbjct: 483 PAWLKGP 489
Score = 35.0 bits (79), Expect = 0.25
Identities = 18/43 (41%), Positives = 20/43 (46%)
Query: 61 GAAAAALLLHPPPPPPPATAAPPPPPPPPPPPASAAAPASGPP 103
GA+ A P PP PA +A P PP P A A GPP
Sbjct: 1040 GASKAKPPTAPAPPSAPAPSAQPTPPSASVPGKKAREEAPGPP 1082
Score = 33.1 bits (74), Expect = 0.94
Identities = 30/91 (32%), Positives = 35/91 (38%), Gaps = 25/91 (27%)
Query: 51 PGGGAGGEGL---GAAAAALLLHPPPPPPPATA------------APPPPPPPPPPPASA 95
PG A E G + A PP PPP +A PP P P PP S
Sbjct: 8 PGARAAREAFALGGLSCAGAWSSCPPHPPPRSAWLPGGRCSASIGQPPLPAPLPPSHGS- 66
Query: 96 AAPASGPPAPPGLAAGPGPAGGAPTPALVAG 126
+SG P+ P A GAPTP + G
Sbjct: 67 ---SSGHPSKPYYAP------GAPTPRPLHG 88
Score = 32.3 bits (72), Expect = 1.6
Identities = 17/50 (34%), Positives = 21/50 (42%), Gaps = 2/50 (4%)
Query: 60 LGAAAAALLLHPPPPPPPATAAPPPPPPPPPPPASAAAPASGPPAPPGLA 109
LG A+ A P P PP+ AP P PP P PPG++
Sbjct: 1038 LGGASKAK--PPTAPAPPSAPAPSAQPTPPSASVPGKKAREEAPGPPGVS 1085
Score = 32.0 bits (71), Expect = 2.1
Identities = 37/132 (28%), Positives = 50/132 (37%), Gaps = 17/132 (12%)
Query: 9 PPQQQQQQQQLSPPPP------AALAPVSGVVLPAPP--------AVSAGSSPAGSPGGG 54
PP++Q+Q+ L P P A P +V APP A S G PA P G
Sbjct: 299 PPERQEQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGS 358
Query: 55 AGGEG-LGAAAAALLLHPPPPPPPATAAPPPPPPPPPPPASAAAPASGPPAPPGLAAGPG 113
E + + + P AP PP P S+++ +S G+ PG
Sbjct: 359 DLRESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPG 418
Query: 114 PAGG--APTPAL 123
G TPAL
Sbjct: 419 IPGADHYQTPAL 430
Score = 31.2 bits (69), Expect = 3.6
Identities = 18/56 (32%), Positives = 22/56 (39%), Gaps = 2/56 (3%)
Query: 77 PATAAPPPPPPPPPPPASAAAPASGPPAPPGLAAGPGPAGGAPTPALVAGSSAAAP 132
P TA P PP P P A P++ P PGP G + L S + P
Sbjct: 1046 PPTA--PAPPSAPAPSAQPTPPSASVPGKKAREEAPGPPGVSRADMLKLRSLSEGP 1099
Score = 30.4 bits (67), Expect = 6.1
Identities = 27/83 (32%), Positives = 30/83 (36%), Gaps = 25/83 (30%)
Query: 68 LLHPPPPPP----PA-----------------TAAPPPPPPPPPPPASAAAPASGPPAPP 106
LL PPPPP PA T PP P PPP P GPPA
Sbjct: 476 LLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFL---GPPA-S 531
Query: 107 GLAAGPGPAGGAPTPALVAGSSA 129
+ G + PTP SS+
Sbjct: 532 RFSVGTQDSHTPPTPPTPTTSSS 554
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 67.4 bits (163), Expect = 4e-11
Identities = 47/147 (31%), Positives = 54/147 (36%), Gaps = 23/147 (15%)
Query: 3 GQPPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGA 62
G+P PPPQ + + SPP P G P P G P GG +G
Sbjct: 96 GKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQG--- 152
Query: 63 AAAALLLHPPPP-----PPPA------TAAPPPPPPPPPPPASAAAPASGPPAPPGLAAG 111
PPPP PPP ++ PP P PPP P GPP PPG G
Sbjct: 153 --------PPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQP-QGPPPPPGKPQG 203
Query: 112 PGPAGGAPTPALVAGSSAAAPFPHGDS 138
P P GG P P GD+
Sbjct: 204 PPPQGGNKPQGPPPPGKPQGPPPQGDN 230
Score = 63.5 bits (153), Expect = 6e-10
Identities = 48/148 (32%), Positives = 53/148 (35%), Gaps = 24/148 (16%)
Query: 3 GQPPPPPPQ-QQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLG 61
G+P PPPQ + + SPP P G P P G P GG +G
Sbjct: 157 GKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQG-- 214
Query: 62 AAAAALLLHPPPP-----PPPA------TAAPPPPPPPPPPPASAAAPASGPPAPPGLAA 110
PPPP PPP +A PP P PPP P GPP PPG
Sbjct: 215 ---------PPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQP-QGPPPPPGKPQ 264
Query: 111 GPGPAGGAPTPALVAGSSAAAPFPHGDS 138
GP P GG P P G S
Sbjct: 265 GPPPQGGNKPQGPPPPGKPQGPPPQGGS 292
Score = 63.5 bits (153), Expect = 6e-10
Identities = 48/148 (32%), Positives = 53/148 (35%), Gaps = 24/148 (16%)
Query: 3 GQPPPPPPQQQQQQQQL-SPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLG 61
G+P PPPQ + Q SPP P G P P G P GG +G
Sbjct: 219 GKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQG-- 276
Query: 62 AAAAALLLHPPPP-----PPPA------TAAPPPPPPPPPPPASAAAPASGPPAPPGLAA 110
PPPP PPP ++ PP P PPP P GPP PPG
Sbjct: 277 ---------PPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQP-QGPPPPPGKPQ 326
Query: 111 GPGPAGGAPTPALVAGSSAAAPFPHGDS 138
GP P GG P P G S
Sbjct: 327 GPPPQGGNKPQGPPPPGKPQGPPPQGGS 354
Score = 62.8 bits (151), Expect = 1e-09
Identities = 45/138 (32%), Positives = 50/138 (36%), Gaps = 26/138 (18%)
Query: 3 GQPPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGA 62
G+P PPPQ Q Q PPPP P P G+ P G P G
Sbjct: 55 GKPQGPPPQGGNQPQ--GPPPPPGK--------PQGPPPQGGNKPQGPPPPGKP------ 98
Query: 63 AAAALLLHPPPPPPPATAAPPPPPPPP--PPPASAAAPASGPPAPPGLAAGPGPAGGAPT 120
PPP + +P PP P PPP P GPP PPG GP P GG
Sbjct: 99 -------QGPPPQGDKSRSPRSPPGKPQGPPPQGGNQP-QGPPPPPGKPQGPPPQGGNKP 150
Query: 121 PALVAGSSAAAPFPHGDS 138
P P GD+
Sbjct: 151 QGPPPPGKPQGPPPQGDN 168
Score = 54.3 bits (129), Expect = 4e-07
Identities = 53/169 (31%), Positives = 57/169 (33%), Gaps = 40/169 (23%)
Query: 3 GQPPPPPPQQQQQQQQLSPPP--PAALAPVSGVVL--PAPPAVSAGSSPAGS-------- 50
G+P PPPQ Q Q PPP P P G P PP G P G
Sbjct: 240 GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRS 299
Query: 51 -PGGGAGGEGLGAAAAALLLHPPPPP-----PPATAA-----PPPPPPPPPPPASAAAPA 99
PG G G PPPPP PP PPPP P PP + +
Sbjct: 300 PPGKPQGPPPQGGNQPQ---GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKS 356
Query: 100 SGPPAPPGLAAG------------PGPAGGAP--TPALVAGSSAAAPFP 134
+PPG G P PAGG P A AG P P
Sbjct: 357 RSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRP 405
Score = 52.4 bits (124), Expect = 1e-06
Identities = 42/126 (33%), Positives = 47/126 (37%), Gaps = 23/126 (18%)
Query: 3 GQPPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGA--GGEGL 60
G+P PPPQ Q Q PPPP P P G+ P G P G G
Sbjct: 302 GKPQGPPPQGGNQPQ--GPPPPPGK--------PQGPPPQGGNKPQGPPPPGKPQGPPPQ 351
Query: 61 GAAAAALLLHPPPPP--PPATAAPPPPPPPPP----PPASAAAPASGPPAPPGLAAGPGP 114
G + + PP P PP P PPPP P A PA P PP P
Sbjct: 352 GGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPP-----RPP 406
Query: 115 AGGAPT 120
GG P+
Sbjct: 407 QGGRPS 412
Score = 47.4 bits (111), Expect = 5e-05
Identities = 27/75 (36%), Positives = 29/75 (38%), Gaps = 6/75 (8%)
Query: 70 HPPPPPPPATAAPPPPPPPP-----PPPASAAAPASGPPAPPGLAAGPGPAGGAPTPALV 124
+P PP P PP PP PPP P GPP PPG GP P GG
Sbjct: 35 NPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQP-QGPPPPPGKPQGPPPQGGNKPQGPP 93
Query: 125 AGSSAAAPFPHGDSA 139
P P GD +
Sbjct: 94 PPGKPQGPPPQGDKS 108
Score = 43.1 bits (100), Expect = 0.001
Identities = 31/103 (30%), Positives = 36/103 (34%), Gaps = 20/103 (19%)
Query: 39 PAVSAGSSPAGSPGGGAGGEGLGAAAAALLLHPPPPPPPATAAPPP-----PPPPPPPPA 93
P++ AG+ P GG +G PP PP PPP P PPPPP
Sbjct: 29 PSLIAGNPQGAPPQGGNKPQG------------PPSPPGKPQGPPPQGGNQPQGPPPPPG 76
Query: 94 SAAAPASGPPAPPGLAAGPGPAGGAPTPALVAGSSAAAPFPHG 136
P PP GP P G P S + P G
Sbjct: 77 KPQGP---PPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPG 116
Score = 30.8 bits (68), Expect = 4.7
Identities = 27/88 (30%), Positives = 29/88 (32%), Gaps = 33/88 (37%)
Query: 2 SGQPPPPPPQ---QQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGE 58
S + PP PQ QQ+ PPPPA P P P PAG P G
Sbjct: 358 SARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQ----PQAP-------PAGQPQG----- 401
Query: 59 GLGAAAAALLLHPPPPPPPATAAPPPPP 86
PP PP P PP
Sbjct: 402 --------------PPRPPQGGRPSRPP 415
>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
1 [Homo sapiens]
Length = 1250
Score = 67.0 bits (162), Expect = 6e-11
Identities = 58/187 (31%), Positives = 72/187 (38%), Gaps = 28/187 (14%)
Query: 6 PPPPPQQQQQQQQLSPPPPAALAPVSGVVL---------PAPPAVSAGSSPAGSPGGGAG 56
P PPP +QQ + PPP+ L+PV VV P PPA+ S P
Sbjct: 834 PVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAME--SQPLKPVPANVA 891
Query: 57 GEGLGAAAAALLLHPPPPPPPATAAPPPPP------PPPPPPASAAAPASGPPAPPGLAA 110
+ A A P P P+ PPPPP PPPPP PA PP PP +
Sbjct: 892 PQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPS---PVPAPPPPPPPTASP 948
Query: 111 GP---GPAGGAPTPALVAGSSAAAPFPHGDSALNEQEKELQRRLKRLYPAVD---EQETP 164
P G G + G P P +S++ KR P+VD + TP
Sbjct: 949 TPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKR--PSVDSLVSKFTP 1006
Query: 165 LPRSWSP 171
S SP
Sbjct: 1007 PAESGSP 1013
Score = 66.2 bits (160), Expect = 1e-10
Identities = 48/139 (34%), Positives = 60/139 (43%), Gaps = 16/139 (11%)
Query: 1 MSGQPPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGL 60
++ Q PPPP + Q L P PA +AP S + A P S P SP +
Sbjct: 865 IASQFPPPPTPPAMESQPLK-PVPANVAPQSPPAVKAKPKWQPSSIPVPSP------DFP 917
Query: 61 GAAAAALLLHPPPPPPPATAAPPPPPPPPPPPASAAAPASGPPA-PPGLAAGPGPAGGAP 119
+ L+ PPPPP P P PPPPPPP AS SG P + PG P
Sbjct: 918 PPPPESSLVFPPPPPSPV----PAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPP 973
Query: 120 TP----ALVAGSSAAAPFP 134
TP ++ + S A P P
Sbjct: 974 TPQRNSSIKSSSGAEHPEP 992
Score = 62.0 bits (149), Expect = 2e-09
Identities = 47/134 (35%), Positives = 51/134 (38%), Gaps = 30/134 (22%)
Query: 5 PPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGAA- 63
PPPPPP PPPP P LP+ A SAGS+ A+
Sbjct: 629 PPPPPP----------PPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQ 678
Query: 64 -AAALLLHPPPP-------------PPPATAAPPPPPPPPPPPASAAAPASGPPAPPGLA 109
+ AL P PP PP PPPPPPPPP P SA A P P L
Sbjct: 679 HSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSL- 737
Query: 110 AGPGPAGGAPTPAL 123
P AP P L
Sbjct: 738 ----PQFSAPPPPL 747
Score = 54.7 bits (130), Expect = 3e-07
Identities = 43/138 (31%), Positives = 49/138 (35%), Gaps = 34/138 (24%)
Query: 6 PPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGAAAA 65
PP PP Q Q + P L P +GVV P PP P P G+ L A
Sbjct: 686 PPTPPVMQSQSVK-----PQILVPPNGVVPPPPP-------PPPPPTPGSAMAQLKPAPC 733
Query: 66 A------------LLLH----------PPPPPPPATAAPPPPPPPPPPPASAAAPASGPP 103
A L +H P PPPPP AP PP PP P + AP S
Sbjct: 734 APSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKT 793
Query: 104 APPGLAAGPGPAGGAPTP 121
P + P P P
Sbjct: 794 VAPVVTQAAPPTPTPPVP 811
Score = 53.5 bits (127), Expect = 7e-07
Identities = 41/145 (28%), Positives = 54/145 (37%), Gaps = 7/145 (4%)
Query: 2 SGQPPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLG 61
S PPP Q Q Q++PP P P+ + P P + PA +
Sbjct: 741 SAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQ 800
Query: 62 AAAAALLLHPPPPPPPATAAPPPPP---PPPPPPASAAAPASGPPAPPGLAAGPGPAGGA 118
AA P PP PPA P P PP PP P P A P P+ +
Sbjct: 801 AAPPT----PTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLS 856
Query: 119 PTPALVAGSSAAAPFPHGDSALNEQ 143
P P++V ++ P P A+ Q
Sbjct: 857 PVPSVVKQIASQFPPPPTPPAMESQ 881
Score = 50.4 bits (119), Expect = 6e-06
Identities = 26/65 (40%), Positives = 32/65 (49%), Gaps = 4/65 (6%)
Query: 68 LLHPPPPPP----PATAAPPPPPPPPPPPASAAAPASGPPAPPGLAAGPGPAGGAPTPAL 123
L+ P P P P TA+ P PP PPPPP P PP PP L + P+ G+ P
Sbjct: 605 LVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMF 664
Query: 124 VAGSS 128
V S+
Sbjct: 665 VKYST 669
Score = 45.8 bits (107), Expect = 1e-04
Identities = 51/186 (27%), Positives = 64/186 (34%), Gaps = 42/186 (22%)
Query: 6 PPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPG------GGAGGEG 59
PPPPP+ + PPPP + PV P PP S +GSPG GG+
Sbjct: 917 PPPPPESSL----VFPPPPPS--PVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGK- 969
Query: 60 LGAAAAALLLHPPPPP------PPATAAPPPPPPPP---------PPPASAAAPASGPPA 104
PPP P ++ A P P P PPA + +P+
Sbjct: 970 ----------KPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLP 1019
Query: 105 PPGLAAGPGP--AGGAPTPALVAGS--SAAAPFPHGDSALNEQEKELQRRLKRLYPAVDE 160
PP PG G P ++ SA AP G + E P E
Sbjct: 1020 PPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPE 1079
Query: 161 QETPLP 166
E PLP
Sbjct: 1080 TELPLP 1085
Score = 41.6 bits (96), Expect = 0.003
Identities = 44/175 (25%), Positives = 54/175 (30%), Gaps = 9/175 (5%)
Query: 5 PPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGAAA 64
PPPPPP S P + S PP +S S G E +
Sbjct: 938 PPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSV 997
Query: 65 AALLLHPPPPPPPATAAPPPPPPPPPPPASAAAPASGPPAPPGLAAGPGPAGGAPTPALV 124
+L+ PP + + PPP PP SG P L G A
Sbjct: 998 DSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRG 1057
Query: 125 AGSSAAAPFPHGDSALNEQEKELQRRLKRL-YPAVDEQET--------PLPRSWS 170
S P P DS E + L + PAV T P P+ WS
Sbjct: 1058 KDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWS 1112
Score = 30.4 bits (67), Expect = 6.1
Identities = 19/57 (33%), Positives = 26/57 (45%), Gaps = 2/57 (3%)
Query: 77 PATAAPPPPPPPPP--PPASAAAPASGPPAPPGLAAGPGPAGGAPTPALVAGSSAAA 131
P T+ PP P P P +A+ P+ P PP P P P P L + S+ +A
Sbjct: 601 PYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSA 657
>gi|33356148 formin-like 1 [Homo sapiens]
Length = 1100
Score = 67.0 bits (162), Expect = 6e-11
Identities = 43/131 (32%), Positives = 51/131 (38%), Gaps = 18/131 (13%)
Query: 2 SGQPPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLG 61
+G P P + +PPPP P+ G LP+P + P P G+
Sbjct: 523 TGSPSPDLAPAAEPAPGAAPPPPP---PLPG--LPSPQEAPPSAPPQAPPLPGSP----- 572
Query: 62 AAAAALLLHPPPPPPPATAAPPPPPPPPPPPASAAAPASGPPAPPGLAAGPGPAGGAPTP 121
PPP PP PPPPPPPPPPP + PP PP GP A G
Sbjct: 573 --------EPPPAPPLPGDLPPPPPPPPPPPGTDGPVPPPPPPPPPPPGGPPDALGRRDS 624
Query: 122 ALVAGSSAAAP 132
L G A P
Sbjct: 625 ELGPGVKAKKP 635
Score = 55.5 bits (132), Expect = 2e-07
Identities = 41/128 (32%), Positives = 44/128 (34%), Gaps = 48/128 (37%)
Query: 24 PAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGAAAAALLLHPPPPPPPATAAP- 82
P A+A SG P P + SP +P A GAA PPPPPP P
Sbjct: 505 PVAVATPSGGDAPTPGVPTGSPSPDLAP---AAEPAPGAA--------PPPPPPLPGLPS 553
Query: 83 -------------------------------PPPPPPPPPPASAAAPASGPPAPPGLAAG 111
PPPPPPPPPP P PP PP
Sbjct: 554 PQEAPPSAPPQAPPLPGSPEPPPAPPLPGDLPPPPPPPPPPPGTDGPVPPPPPPP----- 608
Query: 112 PGPAGGAP 119
P P GG P
Sbjct: 609 PPPPGGPP 616
Score = 53.9 bits (128), Expect = 5e-07
Identities = 32/85 (37%), Positives = 37/85 (43%), Gaps = 1/85 (1%)
Query: 52 GGGAGGEGLGAAAAALLLHPPPPPPPATAAPPPPPPPPPPPASAAAPASGPPAPPGLAAG 111
GG A G+ + + L P P P AAPPPPPP P P+ AP S PP P L
Sbjct: 513 GGDAPTPGVPTGSPSPDLAPAAEPAPG-AAPPPPPPLPGLPSPQEAPPSAPPQAPPLPGS 571
Query: 112 PGPAGGAPTPALVAGSSAAAPFPHG 136
P P P P + P P G
Sbjct: 572 PEPPPAPPLPGDLPPPPPPPPPPPG 596
Score = 40.8 bits (94), Expect = 0.005
Identities = 31/93 (33%), Positives = 34/93 (36%), Gaps = 42/93 (45%)
Query: 1 MSGQPPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGL 60
+ G P PPP +PP P L P P PP P G+ G
Sbjct: 568 LPGSPEPPP----------APPLPGDLPP------PPPPP----PPPPGTDG-------- 599
Query: 61 GAAAAALLLHPPPPPPPATAAPPPPPPPPPPPA 93
P PPPPP PPPPPP PP A
Sbjct: 600 ----------PVPPPPP----PPPPPPGGPPDA 618
Score = 38.5 bits (88), Expect = 0.022
Identities = 37/135 (27%), Positives = 43/135 (31%), Gaps = 10/135 (7%)
Query: 1 MSGQPPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPA-GSPGGGAGGEG 59
M PP P++ PPAA S + L G PG E
Sbjct: 453 MGASRRPPEPEKA---------PPAAPTRPSALELKVEELEEKGLIRILRGPGDAVSIEI 503
Query: 60 LGAAAAALLLHPPPPPPPATAAPPPPPPPPPPPASAAAPASGPPAPPGLAAGPGPAGGAP 119
L A A P P T +P P P PA AAP PP P + P P
Sbjct: 504 LPVAVATPSGGDAPTPGVPTGSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPP 563
Query: 120 TPALVAGSSAAAPFP 134
+ GS P P
Sbjct: 564 QAPPLPGSPEPPPAP 578
>gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 66.6 bits (161), Expect = 8e-11
Identities = 46/131 (35%), Positives = 52/131 (39%), Gaps = 17/131 (12%)
Query: 5 PPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGAAA 64
PPPPPP Q PPPPA L GV+ PAPP ++ P + AA
Sbjct: 353 PPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPP--------VARAA 404
Query: 65 AALLLHPPPPPPPATAAPPPPPPPPPPPASAAAPASGPPAPPGLAAGPGPAGGAPTPALV 124
P P P PPPPPPPP S P LA P+G PTP
Sbjct: 405 PVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALA--HPPSGLHPTP--- 459
Query: 125 AGSSAAAPFPH 135
+ AP PH
Sbjct: 460 ----STAPGPH 466
Score = 65.5 bits (158), Expect = 2e-10
Identities = 48/150 (32%), Positives = 63/150 (42%), Gaps = 23/150 (15%)
Query: 4 QPPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAG-SPGGGAGGEGLGA 62
+PPPPPP + P P ++ +G++ P + + G +P SP L +
Sbjct: 277 EPPPPPPMHGAGDAK---PIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPS 333
Query: 63 AAAALLLH-----------PPPPPPPATAAPPPPPPPPPPPASAAA----PASGPPAPPG 107
A + L PPPPPPPATA P PPPP P A PA P APP
Sbjct: 334 ALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPL 393
Query: 108 LAAGPGPAGGAPTPALVAGSSAAAPFPHGD 137
+ P A AP V + P P G+
Sbjct: 394 VQPSPPVARAAP----VCETVPVHPLPQGE 419
Score = 64.7 bits (156), Expect = 3e-10
Identities = 41/133 (30%), Positives = 54/133 (40%), Gaps = 33/133 (24%)
Query: 4 QPPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPA-GSPGGGAGGEGLGA 62
+P PPP + P P ++ +G++ P + + G +P SP
Sbjct: 274 RPHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSP----------- 322
Query: 63 AAAALLLHPPPPPPPATAA--------------PPPPPPPPPPPASAAAPASGPPAPPGL 108
PPPPPPP +A PPP PPPPPPPA+A + PP P L
Sbjct: 323 -------TPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPL 375
Query: 109 AAGPGPAGGAPTP 121
PG AP P
Sbjct: 376 QIAPGVLHPAPPP 388
Score = 41.6 bits (96), Expect = 0.003
Identities = 33/108 (30%), Positives = 37/108 (34%), Gaps = 41/108 (37%)
Query: 1 MSGQPPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGL 60
+ G PPPPPP P PP + P S V + A
Sbjct: 420 VQGLPPPPPP---------PPLPPPGIRPSSPVTVTA----------------------- 447
Query: 61 GAAAAALLLHPPP--PPPPATAAPPPPPPPPPPPASAAAPASGPPAPP 106
L HPP P P+TA P P PP P S PAS P P
Sbjct: 448 -------LAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKRHP 488
>gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 66.6 bits (161), Expect = 8e-11
Identities = 46/131 (35%), Positives = 52/131 (39%), Gaps = 17/131 (12%)
Query: 5 PPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGAAA 64
PPPPPP Q PPPPA L GV+ PAPP ++ P + AA
Sbjct: 353 PPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPP--------VARAA 404
Query: 65 AALLLHPPPPPPPATAAPPPPPPPPPPPASAAAPASGPPAPPGLAAGPGPAGGAPTPALV 124
P P P PPPPPPPP S P LA P+G PTP
Sbjct: 405 PVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALA--HPPSGLHPTP--- 459
Query: 125 AGSSAAAPFPH 135
+ AP PH
Sbjct: 460 ----STAPGPH 466
Score = 65.5 bits (158), Expect = 2e-10
Identities = 48/150 (32%), Positives = 63/150 (42%), Gaps = 23/150 (15%)
Query: 4 QPPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAG-SPGGGAGGEGLGA 62
+PPPPPP + P P ++ +G++ P + + G +P SP L +
Sbjct: 277 EPPPPPPMHGAGDAK---PIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPS 333
Query: 63 AAAALLLH-----------PPPPPPPATAAPPPPPPPPPPPASAAA----PASGPPAPPG 107
A + L PPPPPPPATA P PPPP P A PA P APP
Sbjct: 334 ALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPL 393
Query: 108 LAAGPGPAGGAPTPALVAGSSAAAPFPHGD 137
+ P A AP V + P P G+
Sbjct: 394 VQPSPPVARAAP----VCETVPVHPLPQGE 419
Score = 64.7 bits (156), Expect = 3e-10
Identities = 41/133 (30%), Positives = 54/133 (40%), Gaps = 33/133 (24%)
Query: 4 QPPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPA-GSPGGGAGGEGLGA 62
+P PPP + P P ++ +G++ P + + G +P SP
Sbjct: 274 RPHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSP----------- 322
Query: 63 AAAALLLHPPPPPPPATAA--------------PPPPPPPPPPPASAAAPASGPPAPPGL 108
PPPPPPP +A PPP PPPPPPPA+A + PP P L
Sbjct: 323 -------TPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPL 375
Query: 109 AAGPGPAGGAPTP 121
PG AP P
Sbjct: 376 QIAPGVLHPAPPP 388
Score = 41.6 bits (96), Expect = 0.003
Identities = 33/108 (30%), Positives = 37/108 (34%), Gaps = 41/108 (37%)
Query: 1 MSGQPPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGL 60
+ G PPPPPP P PP + P S V + A
Sbjct: 420 VQGLPPPPPP---------PPLPPPGIRPSSPVTVTA----------------------- 447
Query: 61 GAAAAALLLHPPP--PPPPATAAPPPPPPPPPPPASAAAPASGPPAPP 106
L HPP P P+TA P P PP P S PAS P P
Sbjct: 448 -------LAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKRHP 488
>gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 66.6 bits (161), Expect = 8e-11
Identities = 46/131 (35%), Positives = 52/131 (39%), Gaps = 17/131 (12%)
Query: 5 PPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGAAA 64
PPPPPP Q PPPPA L GV+ PAPP ++ P + AA
Sbjct: 353 PPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPP--------VARAA 404
Query: 65 AALLLHPPPPPPPATAAPPPPPPPPPPPASAAAPASGPPAPPGLAAGPGPAGGAPTPALV 124
P P P PPPPPPPP S P LA P+G PTP
Sbjct: 405 PVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALA--HPPSGLHPTP--- 459
Query: 125 AGSSAAAPFPH 135
+ AP PH
Sbjct: 460 ----STAPGPH 466
Score = 65.5 bits (158), Expect = 2e-10
Identities = 48/150 (32%), Positives = 63/150 (42%), Gaps = 23/150 (15%)
Query: 4 QPPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAG-SPGGGAGGEGLGA 62
+PPPPPP + P P ++ +G++ P + + G +P SP L +
Sbjct: 277 EPPPPPPMHGAGDAK---PIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPS 333
Query: 63 AAAALLLH-----------PPPPPPPATAAPPPPPPPPPPPASAAA----PASGPPAPPG 107
A + L PPPPPPPATA P PPPP P A PA P APP
Sbjct: 334 ALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPL 393
Query: 108 LAAGPGPAGGAPTPALVAGSSAAAPFPHGD 137
+ P A AP V + P P G+
Sbjct: 394 VQPSPPVARAAP----VCETVPVHPLPQGE 419
Score = 64.7 bits (156), Expect = 3e-10
Identities = 41/133 (30%), Positives = 54/133 (40%), Gaps = 33/133 (24%)
Query: 4 QPPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPA-GSPGGGAGGEGLGA 62
+P PPP + P P ++ +G++ P + + G +P SP
Sbjct: 274 RPHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSP----------- 322
Query: 63 AAAALLLHPPPPPPPATAA--------------PPPPPPPPPPPASAAAPASGPPAPPGL 108
PPPPPPP +A PPP PPPPPPPA+A + PP P L
Sbjct: 323 -------TPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPL 375
Query: 109 AAGPGPAGGAPTP 121
PG AP P
Sbjct: 376 QIAPGVLHPAPPP 388
Score = 41.6 bits (96), Expect = 0.003
Identities = 33/108 (30%), Positives = 37/108 (34%), Gaps = 41/108 (37%)
Query: 1 MSGQPPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGL 60
+ G PPPPPP P PP + P S V + A
Sbjct: 420 VQGLPPPPPP---------PPLPPPGIRPSSPVTVTA----------------------- 447
Query: 61 GAAAAALLLHPPP--PPPPATAAPPPPPPPPPPPASAAAPASGPPAPP 106
L HPP P P+TA P P PP P S PAS P P
Sbjct: 448 -------LAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKRHP 488
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.132 0.404
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,603,597
Number of Sequences: 37866
Number of extensions: 2772688
Number of successful extensions: 115415
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1829
Number of HSP's successfully gapped in prelim test: 1671
Number of HSP's that attempted gapping in prelim test: 24019
Number of HSP's gapped (non-prelim): 31782
length of query: 729
length of database: 18,247,518
effective HSP length: 110
effective length of query: 619
effective length of database: 14,082,258
effective search space: 8716917702
effective search space used: 8716917702
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.