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Search of human proteins with 39753957
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|39753957 lamina-associated polypeptide 1B [Homo sapiens]
(583 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|39753957 lamina-associated polypeptide 1B [Homo sapiens] 1160 0.0
gi|21450775 torsin A interacting protein 2 [Homo sapiens] 294 1e-79
gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens] 47 6e-05
gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu... 43 7e-04
gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2 pre... 43 7e-04
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 42 0.002
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 42 0.002
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 41 0.003
gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithora... 41 0.003
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 41 0.003
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 41 0.003
gi|33356174 pinin, desmosome associated protein [Homo sapiens] 41 0.003
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)... 41 0.003
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)... 41 0.003
gi|150378493 MYST histone acetyltransferase (monocytic leukemia)... 41 0.003
gi|4505257 moesin [Homo sapiens] 40 0.005
gi|148746195 trichohyalin [Homo sapiens] 40 0.005
gi|4759208 TAO kinase 2 isoform 1 [Homo sapiens] 40 0.005
gi|197209826 chromosome 2 open reading frame 21 isoform 1 [Homo ... 40 0.006
gi|45439370 TAO kinase 1 [Homo sapiens] 39 0.010
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 39 0.010
gi|153792074 proline rich 12 [Homo sapiens] 39 0.010
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 39 0.013
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 39 0.017
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 38 0.023
gi|226958575 RAS protein activator like 2 isoform 2 [Homo sapiens] 38 0.029
gi|4758808 RAS protein activator like 2 isoform 1 [Homo sapiens] 38 0.029
gi|195927037 DNA (cytosine-5-)-methyltransferase 1 isoform a [Ho... 38 0.029
gi|34878777 ring finger protein 20 [Homo sapiens] 37 0.038
gi|47578107 delangin isoform B [Homo sapiens] 37 0.038
>gi|39753957 lamina-associated polypeptide 1B [Homo sapiens]
Length = 583
Score = 1160 bits (3002), Expect = 0.0
Identities = 583/583 (100%), Positives = 583/583 (100%)
Query: 1 MAGDGRRAEAVREGWGVYVTPRAPIREGRGRLAPQNGGSSDAPAYRTPPSRQGRREVRFS 60
MAGDGRRAEAVREGWGVYVTPRAPIREGRGRLAPQNGGSSDAPAYRTPPSRQGRREVRFS
Sbjct: 1 MAGDGRRAEAVREGWGVYVTPRAPIREGRGRLAPQNGGSSDAPAYRTPPSRQGRREVRFS 60
Query: 61 DEPPEVYGDFEPLVAKERSPVGKRTRLEEFRSDSAKEEVRESAYYLRSRQRRQPRPQETE 120
DEPPEVYGDFEPLVAKERSPVGKRTRLEEFRSDSAKEEVRESAYYLRSRQRRQPRPQETE
Sbjct: 61 DEPPEVYGDFEPLVAKERSPVGKRTRLEEFRSDSAKEEVRESAYYLRSRQRRQPRPQETE 120
Query: 121 EMKTRRTTRLQQQHSEQPPLQPSPVMTRRGLRDSHSSEEDEASSQTDLSQTISKKTVRSI 180
EMKTRRTTRLQQQHSEQPPLQPSPVMTRRGLRDSHSSEEDEASSQTDLSQTISKKTVRSI
Sbjct: 121 EMKTRRTTRLQQQHSEQPPLQPSPVMTRRGLRDSHSSEEDEASSQTDLSQTISKKTVRSI 180
Query: 181 QEAPVSEDLVIRLRRPPLRYPRYEATSVQQKVNFSEEGETEEDDQDSSHSSVTTVKARSR 240
QEAPVSEDLVIRLRRPPLRYPRYEATSVQQKVNFSEEGETEEDDQDSSHSSVTTVKARSR
Sbjct: 181 QEAPVSEDLVIRLRRPPLRYPRYEATSVQQKVNFSEEGETEEDDQDSSHSSVTTVKARSR 240
Query: 241 DSDESGDKTTRSSSQYIESFWQSSQSQNFTAHDKQPSVLSSGYQKTPQEWAPQTARIRTR 300
DSDESGDKTTRSSSQYIESFWQSSQSQNFTAHDKQPSVLSSGYQKTPQEWAPQTARIRTR
Sbjct: 241 DSDESGDKTTRSSSQYIESFWQSSQSQNFTAHDKQPSVLSSGYQKTPQEWAPQTARIRTR 300
Query: 301 MQNDSILKSELGNQSPSTSSRQVTGQPQNASFVKRNRWWLLPLIAALASGSFWFFSTPEV 360
MQNDSILKSELGNQSPSTSSRQVTGQPQNASFVKRNRWWLLPLIAALASGSFWFFSTPEV
Sbjct: 301 MQNDSILKSELGNQSPSTSSRQVTGQPQNASFVKRNRWWLLPLIAALASGSFWFFSTPEV 360
Query: 361 ETTAVQEFQNQMNQLKNKYQGQDEKLWKRSQTFLEKHLNSSHPRSQPAILLLTAARDAEE 420
ETTAVQEFQNQMNQLKNKYQGQDEKLWKRSQTFLEKHLNSSHPRSQPAILLLTAARDAEE
Sbjct: 361 ETTAVQEFQNQMNQLKNKYQGQDEKLWKRSQTFLEKHLNSSHPRSQPAILLLTAARDAEE 420
Query: 421 ALRCLSEQIADAYSSFRSVRAIRIDGTDKATQDSDTVKLEVDQELSNGFKNGQNAAVVHR 480
ALRCLSEQIADAYSSFRSVRAIRIDGTDKATQDSDTVKLEVDQELSNGFKNGQNAAVVHR
Sbjct: 421 ALRCLSEQIADAYSSFRSVRAIRIDGTDKATQDSDTVKLEVDQELSNGFKNGQNAAVVHR 480
Query: 481 FESFPAGSTLIFYKYCDHENAAFKDVALVLTVLLEEETLGTSLGLKEVEEKVRDFLKVKF 540
FESFPAGSTLIFYKYCDHENAAFKDVALVLTVLLEEETLGTSLGLKEVEEKVRDFLKVKF
Sbjct: 481 FESFPAGSTLIFYKYCDHENAAFKDVALVLTVLLEEETLGTSLGLKEVEEKVRDFLKVKF 540
Query: 541 TNSNTPNSYNHMDPDKLNGLWSRISHLVLPVQPENALKRGICL 583
TNSNTPNSYNHMDPDKLNGLWSRISHLVLPVQPENALKRGICL
Sbjct: 541 TNSNTPNSYNHMDPDKLNGLWSRISHLVLPVQPENALKRGICL 583
>gi|21450775 torsin A interacting protein 2 [Homo sapiens]
Length = 470
Score = 294 bits (753), Expect = 1e-79
Identities = 149/244 (61%), Positives = 188/244 (77%), Gaps = 4/244 (1%)
Query: 343 LIAALASGSFWFFSTPEVETT---AVQEFQNQMNQLKNKYQGQDEKLWKRSQTFLEKHLN 399
++A +AS ++S+P + A++ F Q +QL++K+ GQ LW+R + FL+KHLN
Sbjct: 227 VVAVVASSVNSYYSSPAQQVPKNPALEAFLAQFSQLEDKFPGQSSFLWQRGRKFLQKHLN 286
Query: 400 SSHPRSQPAILLLTAARDAEEALRCLSEQIADAYSSFRSVRAIRIDGTDKATQDSDTVKL 459
+S+P ++PA ++ TAAR+ E L+CLS +ADAY+S + V I+IDG + QDSDTVKL
Sbjct: 287 ASNP-TEPATIIFTAAREGRETLKCLSHHVADAYTSSQKVSPIQIDGAGRTWQDSDTVKL 345
Query: 460 EVDQELSNGFKNGQNAAVVHRFESFPAGSTLIFYKYCDHENAAFKDVALVLTVLLEEETL 519
VD ELS GF+NGQ AAVVH FESFPAGSTLIFYKYCDHENAAFKDVALVLTVLLEEETL
Sbjct: 346 LVDLELSYGFENGQKAAVVHHFESFPAGSTLIFYKYCDHENAAFKDVALVLTVLLEEETL 405
Query: 520 GTSLGLKEVEEKVRDFLKVKFTNSNTPNSYNHMDPDKLNGLWSRISHLVLPVQPENALKR 579
S+G +E EEKVRD L KFTNS+TP S+NHMD DKL+GLWSRISHLVLPVQP ++++
Sbjct: 406 EASVGPRETEEKVRDLLWAKFTNSDTPTSFNHMDSDKLSGLWSRISHLVLPVQPVSSIEE 465
Query: 580 GICL 583
CL
Sbjct: 466 QGCL 469
>gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]
Length = 825
Score = 46.6 bits (109), Expect = 6e-05
Identities = 60/262 (22%), Positives = 98/262 (37%), Gaps = 45/262 (17%)
Query: 34 PQNGGSSDAPAYRTPPSRQGRREVRFSDEPPEVYGDFEPLVAKERSPVGKRTRLEEFRSD 93
P G +APA PP+ + E D +PL+ +E R E +
Sbjct: 400 PAEGALEEAPAKVEPPTVE------------ETLADVQPLLPEE----APREEARELQLS 443
Query: 94 SAKEEVRESAYYLRSRQRRQPRPQETEEMKTRRTTRLQQQHSEQPPLQPSPVMTRRGLRD 153
+A E E A + + P P+ET + + +Q + +PP +P R L +
Sbjct: 444 TAMETPAEEA----PTEFQSPLPKETTAEEA--SAEIQLLAATEPPADETPAEARSPLSE 497
Query: 154 SHSSEEDEASSQTDLSQTISKKTVRSIQEAPVSEDLVIRLRRPPLRYPRYEATSVQQKVN 213
S+EE A Q+ L++ + +EA L+ + P + T + +
Sbjct: 498 ETSAEEAHAEVQSPLAEE------TTAEEASAEIQLLAAIEAPA------DETPAEAQSP 545
Query: 214 FSEEGETEE---DDQDSSHSSVTTVKARSRDSDESGDKTTRSSSQYIESFWQSSQSQNFT 270
SEE EE + Q S V+ +A SG++TT + S+ Q
Sbjct: 546 LSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAEEA--------SAAIQLLA 597
Query: 271 AHDKQPSVLSSGYQKTPQEWAP 292
A + + Q P E AP
Sbjct: 598 ATEASAEEAPAEVQPPPAEEAP 619
>gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1
precursor [Homo sapiens]
Length = 513
Score = 43.1 bits (100), Expect = 7e-04
Identities = 56/230 (24%), Positives = 96/230 (41%), Gaps = 23/230 (10%)
Query: 49 PSRQGRREVRFSDEPPEVYGDFEPLVAKERSPV-----GKRTRLEEFRSDS---AKEEVR 100
PSR+ R+ R S+E D + + +S + T L + R DS ++E+ +
Sbjct: 263 PSRKIFRKSRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSK 322
Query: 101 ESAYYLRSRQRRQPRPQETEE--MKTRRTTRLQQQHSEQPPLQPSPVMTRRGLRDSHSSE 158
E+ S+ P + ++E + ++ + Q+ +P T + D +
Sbjct: 323 ENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVED----Q 378
Query: 159 EDEASSQTDLSQTISKKTVRSIQEAPVSEDLV-IRLRRPPLRYPRYEATSVQQKVNF--- 214
ED SS+ D S T+S S +E SE + P E +S Q+ +
Sbjct: 379 EDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSS 438
Query: 215 -----SEEGETEEDDQDSSHSSVTTVKARSRDSDESGDKTTRSSSQYIES 259
SEE +EEDD DS SS + + S +S S ++ + + IES
Sbjct: 439 SAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSSSEEDGQLKNIEIES 488
>gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2
precursor [Homo sapiens]
Length = 497
Score = 43.1 bits (100), Expect = 7e-04
Identities = 56/230 (24%), Positives = 96/230 (41%), Gaps = 23/230 (10%)
Query: 49 PSRQGRREVRFSDEPPEVYGDFEPLVAKERSPV-----GKRTRLEEFRSDS---AKEEVR 100
PSR+ R+ R S+E D + + +S + T L + R DS ++E+ +
Sbjct: 247 PSRKIFRKSRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSK 306
Query: 101 ESAYYLRSRQRRQPRPQETEE--MKTRRTTRLQQQHSEQPPLQPSPVMTRRGLRDSHSSE 158
E+ S+ P + ++E + ++ + Q+ +P T + D +
Sbjct: 307 ENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVED----Q 362
Query: 159 EDEASSQTDLSQTISKKTVRSIQEAPVSEDLV-IRLRRPPLRYPRYEATSVQQKVNF--- 214
ED SS+ D S T+S S +E SE + P E +S Q+ +
Sbjct: 363 EDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSS 422
Query: 215 -----SEEGETEEDDQDSSHSSVTTVKARSRDSDESGDKTTRSSSQYIES 259
SEE +EEDD DS SS + + S +S S ++ + + IES
Sbjct: 423 SAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSSSEEDGQLKNIEIES 472
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 42.0 bits (97), Expect = 0.002
Identities = 72/315 (22%), Positives = 120/315 (38%), Gaps = 42/315 (13%)
Query: 22 RAPIREGRGRL-APQNGGSSDAPAYRTPPSRQGRREVRFSDEPPEVYGDFEPLVAKERSP 80
R P R GR R P G S + RTP R GR R P G ++ R+P
Sbjct: 650 RTPARRGRSRSRTPARRGRSRS---RTPARRSGRSRSR----TPARRGR-----SRSRTP 697
Query: 81 VGKRTRLEEFRSDSAKEEVRESAYYLRSRQRRQPRPQETEEMKTRRTTRLQQQHSEQPPL 140
R+R ++ VR + R+ QRR +E RT++ + + + P +
Sbjct: 698 RRGRSR--------SRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEM 749
Query: 141 QPSPVMTRRGLRDSHSSEEDEASSQTDLSQTISKKTVRSIQEAPV--------SEDLVIR 192
+ S + +RR S SS +A S+ L +++S + Q++ S +
Sbjct: 750 KKSRISSRRS--RSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAK 807
Query: 193 LRRPPLRYPRYEATSVQQKVNFSEEGETEEDDQDSSHSSVTTVKARSRDSDESGDKTTRS 252
R PP R + +QK S+ + S H V + + S S +S
Sbjct: 808 SRTPPRRSRSSSSPPPKQK---SKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQS 864
Query: 253 SSQYIESFWQSS-----QSQNFTAHDKQPSVLSSGYQKTPQEWAP---QTARIRTRMQND 304
+ S ++SS +S+ + H S TP +P + + + +
Sbjct: 865 VTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIIS 924
Query: 305 SILKSELGNQSPSTS 319
+S G+ SPS S
Sbjct: 925 PRQRSHSGSSSPSPS 939
Score = 38.9 bits (89), Expect = 0.013
Identities = 75/333 (22%), Positives = 115/333 (34%), Gaps = 45/333 (13%)
Query: 6 RRAEAVREGWGVYVTPRAPIREGRGRLAPQNGGSSDAPAYRTPPSRQGRREVRFSDEPPE 65
RR+ + + WG R+P R GR R + G S R SR RR R P
Sbjct: 514 RRSRSAQR-WG---RSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRG-RSHSRSPA 568
Query: 66 VYGDFEPLV----AKERSPVGKRTRLEEFRSDSAKEEVRESAYYLRSRQRRQPRPQETEE 121
G + RS R R + R A RSR R R +
Sbjct: 569 TRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTR 628
Query: 122 MKTRRTTRLQQQHSEQPPLQPSPVMTRRGLRDSHSSEEDEASSQTDLSQTISKKTVRSIQ 181
RR +R S P + +R R S A S+T ++++ RS
Sbjct: 629 SPVRRRSR-----SRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRS 683
Query: 182 EAPVSEDLVIRLRRPPLRYPRYEATSVQQKVNFSEEGETEEDDQDSSHSSVTTVKARSRD 241
P R R R PR + + V + SHS + RS
Sbjct: 684 RTPA------RRGRSRSRTPRRGRSRSRSLVR-----------RGRSHSRTPQRRGRSGS 726
Query: 242 SDESGDKTTRSSSQYIESFWQSSQSQNFTAHDKQPSVLSSGYQK---TPQEWAPQTARIR 298
S E +K+ S +S++ ++ + + S +SS + +P+ A +R
Sbjct: 727 SSERKNKSRTS----------QRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLR 776
Query: 299 TRMQNDSILKSELGNQSPSTSSRQVTGQPQNAS 331
+ S + +Q+P SR + QP+ S
Sbjct: 777 RSLSGSSPCPKQ-KSQTPPRRSRSGSSQPKAKS 808
Score = 36.6 bits (83), Expect = 0.065
Identities = 41/165 (24%), Positives = 65/165 (39%), Gaps = 17/165 (10%)
Query: 132 QQHSEQPPLQPSPVMTRRGLRDSHSSEEDEASSQTDLSQTISKKTVRSIQEA---PVSED 188
QQ S LQP+ RR S SS +SS + S + S + S E PV +
Sbjct: 2516 QQPSALAALQPAK--ERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPE 2573
Query: 189 LVIRLRRPPLRYPRYEATSVQQKVNFSEEGETEEDDQDSSHSSVTTVKARSRDSDESGDK 248
+ ++ P P+ + E + + SS SS ++ + S S S
Sbjct: 2574 VALKRVPSPTPAPKEAVREGRPP----EPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSS 2629
Query: 249 TTRSSSQYIESFWQSSQSQNFTAHDKQPSVLSSGYQKTPQEWAPQ 293
++ SSS SS S + ++ PS G Q P+ +P+
Sbjct: 2630 SSSSSS--------SSSSSSSSSSSSSPSPAKPGPQALPKPASPK 2666
Score = 34.3 bits (77), Expect = 0.32
Identities = 50/223 (22%), Positives = 86/223 (38%), Gaps = 42/223 (18%)
Query: 49 PSRQGRREVRFSDEPPEVYGDFEPLVAKERSPVGKRTRLEEF---------------RSD 93
P R+ R + + EPP+ Y + RSP K+ + ++ R
Sbjct: 153 PQRRAREAKQPAPEPPKPYSLVRES-SSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKK 211
Query: 94 SAKEEVRESAYYLRSRQRRQPRPQETEEMKTRRTTRLQQQHSEQPPLQPSPVMTRRGLRD 153
S+K++ S + R+ R P P+ + K ++ R + P+P R
Sbjct: 212 SSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRS-------TTPAPKSRR----- 259
Query: 154 SHSSEEDEASSQTDLSQTISKKTVRSIQEAPVSEDLVIRLRRP-PLRYPRYEATSVQQKV 212
+H S +++S +D S++ RS A + + R P P R E +
Sbjct: 260 AHRSTSADSASSSDTSRS------RSRSAAAKTHTTALAGRSPSPASGRRGEGDA----- 308
Query: 213 NFSEEGETEEDDQDSSHSSVTTVKARSRDSDESGDKTTRSSSQ 255
FSE G T Q S T + S D+ DK +S+++
Sbjct: 309 PFSEPGTT--STQRPSSPETATKQPSSPYEDKDKDKKEKSATR 349
Score = 31.6 bits (70), Expect = 2.1
Identities = 46/202 (22%), Positives = 73/202 (36%), Gaps = 40/202 (19%)
Query: 20 TPRAPIREGRGRLAPQNGGSSDAPAYRTPPSRQGRREVRFSDEPPEVYGDFEPLVAKERS 79
TP P G PQ S D+ P S V+ S P E Y L K +S
Sbjct: 1003 TPPGPSLSGSKSPCPQEK-SKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQS 1061
Query: 80 PVGKRTRLEEFRSDSAKEEVRESAYYLRSRQRRQPRPQETEEMKTRRTTRLQQQHSEQPP 139
+ RSD++ EVR+S HSE P
Sbjct: 1062 QTSP-----DHRSDTSSPEVRQS-------------------------------HSESPS 1085
Query: 140 LQPSPVMTRRGLRDSHSSEEDEASSQTDLSQTISKKTVRSIQEAPVSEDLVIRLRRPPLR 199
LQ + +G R SS E +S++ + Q + + + ++ +S + R +
Sbjct: 1086 LQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPE-QSRFQSDSSS 1144
Query: 200 YPRYEATSV--QQKVNFSEEGE 219
YP ++ S+ Q ++ +E E
Sbjct: 1145 YPTVDSNSLLGQSRLETAESKE 1166
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 41.6 bits (96), Expect = 0.002
Identities = 45/234 (19%), Positives = 87/234 (37%), Gaps = 5/234 (2%)
Query: 46 RTPPSRQGRREVRFSDEPPEVYGDFEPLVAKERSPVGKRTRLEEFRSDSAKEEVRESAYY 105
R P S++ R + GD ++ + R E +D +E RE +
Sbjct: 29 RRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRH 88
Query: 106 L---RSRQRRQPRPQETEEMKTR-RTTRLQQQHSEQPPLQPSPVMTRRGLRDSHSSEEDE 161
R R+R++ R +E E R R + +++ + Q + RD + + E
Sbjct: 89 RKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRE 148
Query: 162 ASSQTDLSQTISKKTVRSIQEAPVSEDLVIRLRRPPLRYPRYEATSVQQKVNFSEEGETE 221
Q D + ++T R ++ + R R R E ++K N +E+ +E
Sbjct: 149 RERQRDAEKERERQTDRE-RQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSE 207
Query: 222 EDDQDSSHSSVTTVKARSRDSDESGDKTTRSSSQYIESFWQSSQSQNFTAHDKQ 275
+ T R R +D D+ ++ + + + S+ T DK+
Sbjct: 208 RGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKE 261
Score = 36.2 bits (82), Expect = 0.086
Identities = 44/203 (21%), Positives = 76/203 (37%), Gaps = 6/203 (2%)
Query: 76 KERSPVGKRTRLEEFRSDSAKEEVRESAYYLRSRQRRQPRPQETEEMKTR--RTTRLQQQ 133
++R G+R R E + D+ KE R++ R RQ + R +E E K R R R +Q+
Sbjct: 139 RDRQTDGQRER--ERQRDAEKERERQTDRE-RQRQTERNRQKEREREKNRQERRERERQR 195
Query: 134 HSEQPPLQPSPVMTRRGLRDSHSSEEDEASSQTDLSQTISKKTVRSIQEAPVSEDLVIR- 192
E R R+ + E E QTD + +KT R ++ E R
Sbjct: 196 EKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERE 255
Query: 193 LRRPPLRYPRYEATSVQQKVNFSEEGETEEDDQDSSHSSVTTVKARSRDSDESGDKTTRS 252
R R + + + E +T+ Q + T + R R + ++
Sbjct: 256 TERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNR 315
Query: 253 SSQYIESFWQSSQSQNFTAHDKQ 275
+ + + Q T D++
Sbjct: 316 KRERERERERERERQRETERDRE 338
Score = 35.8 bits (81), Expect = 0.11
Identities = 42/192 (21%), Positives = 68/192 (35%), Gaps = 22/192 (11%)
Query: 76 KERSPVGKRTRLEEFRSDSAKEEVRE--------------SAYYLRSRQRRQPRPQETEE 121
+ER +R R E ++ KE RE R RQRR R +ETE
Sbjct: 240 REREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETER 299
Query: 122 MKTRRTTRLQQ-----QHSEQPPLQPSPVMTRRGLRDSHSSEEDEASSQTDLSQTISKKT 176
+ R+ R ++ + + + R RD E + QT++ + +++T
Sbjct: 300 KRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQT 359
Query: 177 VRSIQEAPVSEDLVIRLRRPPLRYPRYEATSVQQKVNFSEEGETEEDDQDSSHSSVTTVK 236
R + E R R R E + + E E D+D T K
Sbjct: 360 GREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRE---TEK 416
Query: 237 ARSRDSDESGDK 248
R R+ D ++
Sbjct: 417 QREREKDRESER 428
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 41.2 bits (95), Expect = 0.003
Identities = 62/245 (25%), Positives = 96/245 (39%), Gaps = 43/245 (17%)
Query: 22 RAPIREGRGRLAPQNGGSSDAPAYRTPPSRQGRREVRFSDEPPEVYGDFEPLVAKERSPV 81
R+P +E + R + + D R+P + RR+ RSP
Sbjct: 501 RSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQ--------------------SRSPN 540
Query: 82 GKRTRLEEFRSDSAKEEVRESAYYLRSRQRRQPR-PQETEEMKTRRTTRLQQQH--SEQP 138
+R R + RS S + E R+S + R RR+ R P + E + R++ ++ H S P
Sbjct: 541 KERDR-SQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSP 599
Query: 139 PLQPSPVMTRRGLRDSHSSEEDEASSQTDLSQ--TISKKTVRSIQEAPVSEDLVIRLRRP 196
Q R ++ S S + + SQ T SK++ S P S D +R
Sbjct: 600 NKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPD----WKRS 655
Query: 197 PLRYPRY------EATSVQQKVNFSEEGETEEDDQDSSHSSVTTVKARSRDSDESGDKTT 250
P R TS F G+T QD S + TT KA G++++
Sbjct: 656 PTRTSSLSQNRTPSKTSSHSPSTFPSGGQTL--SQDDSQADATTSKATL-----PGERSS 708
Query: 251 RSSSQ 255
SSS+
Sbjct: 709 SSSSK 713
>gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 1 [Homo sapiens]
Length = 559
Score = 41.2 bits (95), Expect = 0.003
Identities = 58/285 (20%), Positives = 105/285 (36%), Gaps = 37/285 (12%)
Query: 28 GRGRLAPQNGGSSDAPAYRTPPSRQGRREVRFSDEPPEVYGDFEPLVAKERSPVGKRTRL 87
G GRL + A++ P + +E + P+ G P KR
Sbjct: 234 GEGRLPKEEKAPPPKAAFKEP--KMALKETKLESTSPK--GGPPPPPPPPPRASSKRPAT 289
Query: 88 EEFRSDSAKEEVRESAYYLRSRQRRQPRPQETEEMKTRRTTRLQQQ-HSEQPPLQPSPVM 146
+ SAK++ + S+ RS PR + ++ + + E+ + P
Sbjct: 290 ADSPKPSAKKQKKSSSKGSRSAPGTSPRTSSSSSFSDKKPAKDKSSTRGEKVKAESEPRE 349
Query: 147 TRRGLRDSHSSEEDEASSQTDLSQTISKKTVRSIQEAPVSE-DLVIRLRRPPLRYPRYEA 205
++ L S+ EDEAS +++ +Q+ + S + S+ + + PLR
Sbjct: 350 AKKALEVEESNSEDEASFKSESAQSSPSNSSSSSDSSSDSDFEPSQNHSQGPLR------ 403
Query: 206 TSVQQKVNFSEEGETEEDDQDSSHSSVTTVKARSRDSDESGDKTTRSSSQYIESFWQSSQ 265
+ E+ ++EE D+D S S +E+ KT + + S+
Sbjct: 404 -------SMVEDLQSEESDEDDSSS-----------GEEAAGKTNPGRDSRLS--FSDSE 443
Query: 266 SQNFTAHDKQPSVLSSGYQKTPQEWAPQTARIRTRMQNDSILKSE 310
S N S L S PQ+ P +++ R +S K E
Sbjct: 444 SDN-----SADSSLPSREPPPPQKPPPPNSKVSGRRSPESCSKPE 483
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 41.2 bits (95), Expect = 0.003
Identities = 39/196 (19%), Positives = 81/196 (41%), Gaps = 29/196 (14%)
Query: 92 SDSAKEEVRESAYYLR------------SRQRRQPRPQETEEMKTRRTTRLQQQHSEQPP 139
SDS EE ++ Y R S + ++ +P+E +E+K R ++ + SE
Sbjct: 1286 SDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSD 1345
Query: 140 LQPSPVMTRRGLRDSHSSEEDEASSQTDLSQTISKKTVRSIQEAPVSEDLVIRLRRPPLR 199
Q S G+ + S EDE +T RS ++A + E+ ++ R
Sbjct: 1346 FQES------GVSEEVSESEDEQRPRT-----------RSAKKAELEENQRSYKQKKKRR 1388
Query: 200 YPRYEATSVQQKVNFSEEGETEEDDQDSSHSSVTTVKARSRDSDESGDKTTRSSSQYIES 259
+ + S + + SEE E E+++++ + D +S K + + ++
Sbjct: 1389 RIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKD 1448
Query: 260 FWQSSQSQNFTAHDKQ 275
+++QN +++
Sbjct: 1449 DKLRTETQNALKEEEE 1464
Score = 30.8 bits (68), Expect = 3.6
Identities = 43/231 (18%), Positives = 90/231 (38%), Gaps = 33/231 (14%)
Query: 83 KRTRLEEFRSDSAKEEVRESAYYLRSRQRRQPRPQETEEMKTRRTTRLQQQHSEQPPLQP 142
++T+ E DS E+ +S + + + + R T++ + ++HS++
Sbjct: 770 RQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSE----DEKHSKKG---- 821
Query: 143 SPVMTRRGLRDSHSSEEDEASSQTDLSQTISKKTVRSIQEAPVSEDLVIRLR-RPPLRYP 201
M +G ++ +S+E S D + ++T S + + ++ LR R P +
Sbjct: 822 ---MDNQGHKNLKTSQE---GSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQ 875
Query: 202 RYEATSVQQKVNFSEEGETE-------EDDQDSSHSSVTTVKARSRDSDESGDKTTRSSS 254
+T K++ E+ T E + S H T K K S
Sbjct: 876 ASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTCK-----------KVQDGLS 924
Query: 255 QYIESFWQSSQSQNFTAHDKQPSVLSSGYQKTPQEWAPQTARIRTRMQNDS 305
E F + QS + DK+ S + +K P ++ + ++ + ++ S
Sbjct: 925 DIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSS 975
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 41.2 bits (95), Expect = 0.003
Identities = 39/196 (19%), Positives = 81/196 (41%), Gaps = 29/196 (14%)
Query: 92 SDSAKEEVRESAYYLR------------SRQRRQPRPQETEEMKTRRTTRLQQQHSEQPP 139
SDS EE ++ Y R S + ++ +P+E +E+K R ++ + SE
Sbjct: 1324 SDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSD 1383
Query: 140 LQPSPVMTRRGLRDSHSSEEDEASSQTDLSQTISKKTVRSIQEAPVSEDLVIRLRRPPLR 199
Q S G+ + S EDE +T RS ++A + E+ ++ R
Sbjct: 1384 FQES------GVSEEVSESEDEQRPRT-----------RSAKKAELEENQRSYKQKKKRR 1426
Query: 200 YPRYEATSVQQKVNFSEEGETEEDDQDSSHSSVTTVKARSRDSDESGDKTTRSSSQYIES 259
+ + S + + SEE E E+++++ + D +S K + + ++
Sbjct: 1427 RIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKD 1486
Query: 260 FWQSSQSQNFTAHDKQ 275
+++QN +++
Sbjct: 1487 DKLRTETQNALKEEEE 1502
Score = 30.8 bits (68), Expect = 3.6
Identities = 43/231 (18%), Positives = 90/231 (38%), Gaps = 33/231 (14%)
Query: 83 KRTRLEEFRSDSAKEEVRESAYYLRSRQRRQPRPQETEEMKTRRTTRLQQQHSEQPPLQP 142
++T+ E DS E+ +S + + + + R T++ + ++HS++
Sbjct: 808 RQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSE----DEKHSKKG---- 859
Query: 143 SPVMTRRGLRDSHSSEEDEASSQTDLSQTISKKTVRSIQEAPVSEDLVIRLR-RPPLRYP 201
M +G ++ +S+E S D + ++T S + + ++ LR R P +
Sbjct: 860 ---MDNQGHKNLKTSQE---GSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQ 913
Query: 202 RYEATSVQQKVNFSEEGETE-------EDDQDSSHSSVTTVKARSRDSDESGDKTTRSSS 254
+T K++ E+ T E + S H T K K S
Sbjct: 914 ASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTCK-----------KVQDGLS 962
Query: 255 QYIESFWQSSQSQNFTAHDKQPSVLSSGYQKTPQEWAPQTARIRTRMQNDS 305
E F + QS + DK+ S + +K P ++ + ++ + ++ S
Sbjct: 963 DIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSS 1013
>gi|33356174 pinin, desmosome associated protein [Homo sapiens]
Length = 717
Score = 41.2 bits (95), Expect = 0.003
Identities = 58/285 (20%), Positives = 101/285 (35%), Gaps = 38/285 (13%)
Query: 64 PEVYGDFEP-LVAKERSPVGKRTRLEEFRSDSAKEEVRESAYYLRSRQRRQPRPQETEEM 122
PE+ + EP K SP + + +S ++E +ES +P+P+ +
Sbjct: 427 PEMEFEIEPDKECKSLSPGKENVSALDMEKESEEKEEKES----------EPQPEPVAQP 476
Query: 123 KTRRTTRLQQQHSEQPPLQPSPVMTRRGLRDSHSSEEDEASSQTDLSQTISKKTVRSIQE 182
+ + +LQ Q QP LQ P S DLS + + T + QE
Sbjct: 477 QPQSQPQLQLQSQSQPVLQSQP-----------------PSQPEDLSLAVLQPTPQVTQE 519
Query: 183 A----------PVSEDLVIRLRRPPLRYPRYEATSVQQKVNFSEEGETEEDDQDSSHSSV 232
PV + + P+ E+ S + + S + + S SS
Sbjct: 520 QGHLLPERKDFPVESVKLTEVPVEPVLTVHPESKSKTKTRSRSRGRARNKTSKSRSRSSS 579
Query: 233 TTVKARSRDSDESGDKTTRSSSQYIESFWQSSQSQNFTAHDKQPSVLSSGYQKTPQEWAP 292
++ + S S SG ++ SS S SS + ++ D S SS ++
Sbjct: 580 SSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRG 639
Query: 293 QTARIRTRMQNDSILKSELGNQSPSTSSRQVTGQPQNASFVKRNR 337
+ R D + G + SS+ + + S K +R
Sbjct: 640 HNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSSRDTKGSKDKNSR 684
>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 40.8 bits (94), Expect = 0.003
Identities = 45/208 (21%), Positives = 87/208 (41%), Gaps = 26/208 (12%)
Query: 64 PEVYGDFEPLVAKERSPVGKRTRLEEF------------RSDSAKEEVRESAYYLRSR-- 109
P++ E + KE P+ + + EE D+A EV ++ S
Sbjct: 1202 PKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSP 1261
Query: 110 --QRRQPRPQETEEMKTRRTTRLQQQHSEQPPLQ-PSPVMTRRGLRDSHSSEEDEASSQT 166
+ ++P +E EE K R + +Q EQ L+ P P ++ +++ +A +
Sbjct: 1262 ETETKEPEVEEEEE-KPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDED 1320
Query: 167 DLSQTISKKTVRSIQEAPVSEDLVIRLRRPPLRYPRYEATSVQQKVNFSEEGETE---ED 223
D +KK + ++E P ED+ P ++ +A + + ++ ETE E+
Sbjct: 1321 DGHLESTKK--KELEEQPTREDV---KEEPGVQESFLDANMQKSREKIKDKEETELDSEE 1375
Query: 224 DQDSSHSSVTTVKARSRDSDESGDKTTR 251
+Q S +SV + + + D D T+
Sbjct: 1376 EQPSHDTSVVSEQMAGSEDDHEEDSHTK 1403
Score = 29.6 bits (65), Expect = 8.0
Identities = 39/167 (23%), Positives = 66/167 (39%), Gaps = 15/167 (8%)
Query: 131 QQQHSEQPPLQPSPVMTRRGLRDSHSSEEDEASSQTDLSQTISKKTVRSIQEAPVSEDLV 190
++ +E+P Q + G SH ++E ++ S ++ K V APVS
Sbjct: 795 EEGENEEPQCQERELEISVGKSVSHENKEQDSYSV----ESEKKPEVM----APVSST-- 844
Query: 191 IRLRRPPLRYPRYEATSVQQKVNF--SEEGETEE--DDQDSSHSSVTTVKARSRDSDESG 246
RL + L + A S + + +T+E D+DS T A E G
Sbjct: 845 -RLSKQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSAPQEQYGECG 903
Query: 247 DKTTRSSSQYIESFWQSSQSQNFTAHDKQPSVLSSGYQKTPQEWAPQ 293
+K+ + QY ES Q S+ + D +P + + + W Q
Sbjct: 904 EKSEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQ 950
>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 40.8 bits (94), Expect = 0.003
Identities = 45/208 (21%), Positives = 87/208 (41%), Gaps = 26/208 (12%)
Query: 64 PEVYGDFEPLVAKERSPVGKRTRLEEF------------RSDSAKEEVRESAYYLRSR-- 109
P++ E + KE P+ + + EE D+A EV ++ S
Sbjct: 1202 PKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSP 1261
Query: 110 --QRRQPRPQETEEMKTRRTTRLQQQHSEQPPLQ-PSPVMTRRGLRDSHSSEEDEASSQT 166
+ ++P +E EE K R + +Q EQ L+ P P ++ +++ +A +
Sbjct: 1262 ETETKEPEVEEEEE-KPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDED 1320
Query: 167 DLSQTISKKTVRSIQEAPVSEDLVIRLRRPPLRYPRYEATSVQQKVNFSEEGETE---ED 223
D +KK + ++E P ED+ P ++ +A + + ++ ETE E+
Sbjct: 1321 DGHLESTKK--KELEEQPTREDV---KEEPGVQESFLDANMQKSREKIKDKEETELDSEE 1375
Query: 224 DQDSSHSSVTTVKARSRDSDESGDKTTR 251
+Q S +SV + + + D D T+
Sbjct: 1376 EQPSHDTSVVSEQMAGSEDDHEEDSHTK 1403
Score = 29.6 bits (65), Expect = 8.0
Identities = 39/167 (23%), Positives = 66/167 (39%), Gaps = 15/167 (8%)
Query: 131 QQQHSEQPPLQPSPVMTRRGLRDSHSSEEDEASSQTDLSQTISKKTVRSIQEAPVSEDLV 190
++ +E+P Q + G SH ++E ++ S ++ K V APVS
Sbjct: 795 EEGENEEPQCQERELEISVGKSVSHENKEQDSYSV----ESEKKPEVM----APVSST-- 844
Query: 191 IRLRRPPLRYPRYEATSVQQKVNF--SEEGETEE--DDQDSSHSSVTTVKARSRDSDESG 246
RL + L + A S + + +T+E D+DS T A E G
Sbjct: 845 -RLSKQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSAPQEQYGECG 903
Query: 247 DKTTRSSSQYIESFWQSSQSQNFTAHDKQPSVLSSGYQKTPQEWAPQ 293
+K+ + QY ES Q S+ + D +P + + + W Q
Sbjct: 904 EKSEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQ 950
>gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 40.8 bits (94), Expect = 0.003
Identities = 45/208 (21%), Positives = 87/208 (41%), Gaps = 26/208 (12%)
Query: 64 PEVYGDFEPLVAKERSPVGKRTRLEEF------------RSDSAKEEVRESAYYLRSR-- 109
P++ E + KE P+ + + EE D+A EV ++ S
Sbjct: 1202 PKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSP 1261
Query: 110 --QRRQPRPQETEEMKTRRTTRLQQQHSEQPPLQ-PSPVMTRRGLRDSHSSEEDEASSQT 166
+ ++P +E EE K R + +Q EQ L+ P P ++ +++ +A +
Sbjct: 1262 ETETKEPEVEEEEE-KPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDED 1320
Query: 167 DLSQTISKKTVRSIQEAPVSEDLVIRLRRPPLRYPRYEATSVQQKVNFSEEGETE---ED 223
D +KK + ++E P ED+ P ++ +A + + ++ ETE E+
Sbjct: 1321 DGHLESTKK--KELEEQPTREDV---KEEPGVQESFLDANMQKSREKIKDKEETELDSEE 1375
Query: 224 DQDSSHSSVTTVKARSRDSDESGDKTTR 251
+Q S +SV + + + D D T+
Sbjct: 1376 EQPSHDTSVVSEQMAGSEDDHEEDSHTK 1403
Score = 29.6 bits (65), Expect = 8.0
Identities = 39/167 (23%), Positives = 66/167 (39%), Gaps = 15/167 (8%)
Query: 131 QQQHSEQPPLQPSPVMTRRGLRDSHSSEEDEASSQTDLSQTISKKTVRSIQEAPVSEDLV 190
++ +E+P Q + G SH ++E ++ S ++ K V APVS
Sbjct: 795 EEGENEEPQCQERELEISVGKSVSHENKEQDSYSV----ESEKKPEVM----APVSST-- 844
Query: 191 IRLRRPPLRYPRYEATSVQQKVNF--SEEGETEE--DDQDSSHSSVTTVKARSRDSDESG 246
RL + L + A S + + +T+E D+DS T A E G
Sbjct: 845 -RLSKQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSAPQEQYGECG 903
Query: 247 DKTTRSSSQYIESFWQSSQSQNFTAHDKQPSVLSSGYQKTPQEWAPQ 293
+K+ + QY ES Q S+ + D +P + + + W Q
Sbjct: 904 EKSEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQ 950
>gi|4505257 moesin [Homo sapiens]
Length = 577
Score = 40.4 bits (93), Expect = 0.005
Identities = 39/208 (18%), Positives = 84/208 (40%), Gaps = 16/208 (7%)
Query: 83 KRTRLEEFRSDSAKEEVRESAYYLRSRQRRQPRPQETEEMKTRRTTRLQQQH-------- 134
K+ + E + + E E L+ + + + Q+ E +TRR L+Q+
Sbjct: 328 KKREMAEKEKEKIEREKEELMERLKQIEEQTKKAQQELEEQTRRALELEQERKRAQSEAE 387
Query: 135 ---SEQPPLQPSPVMTRRGLRDSHSSEEDEASSQTDLSQTISK-KTVRSIQEAPVSE-DL 189
E+ + + + RD ++E A +L+ IS+ + R +E+ E
Sbjct: 388 KLAKERQEAEEAKEALLQASRDQKKTQEQLALEMAELTARISQLEMARQKKESEAVEWQQ 447
Query: 190 VIRLRRPPLRYPRYEATSVQQKVNFSEEGETEEDDQDSSHSSVTT---VKARSRDSDESG 246
++ + L R E + + +E E E+D+QD + + + A ++D E
Sbjct: 448 KAQMVQEDLEKTRAELKTAMSTPHVAEPAENEQDEQDENGAEASADLRADAMAKDRSEEE 507
Query: 247 DKTTRSSSQYIESFWQSSQSQNFTAHDK 274
T ++ ++ ++ S+ A D+
Sbjct: 508 RTTEAEKNERVQKHLKALTSELANARDE 535
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 40.4 bits (93), Expect = 0.005
Identities = 46/204 (22%), Positives = 86/204 (42%), Gaps = 33/204 (16%)
Query: 51 RQGRREVRFSDEPPEVYGDFEPLVAKERSPVGKRTRLEEFRSDSAKEEVRESAYYLRSRQ 110
R+ RE ++ +E E+ + E L+ +ER KR R E R K+E+++ L +
Sbjct: 982 RRQEREKKYREEE-ELQQEEEQLLREERE---KRRRQEWERQYRKKDELQQEEEQLLREE 1037
Query: 111 RRQPRPQETE-------------------EMKTRRTTRLQQQHSEQPPLQPS-------- 143
R + R QE E E +TRR L++Q+ ++ LQ
Sbjct: 1038 REKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREE 1097
Query: 144 PVMTRRGLRDSHSSEEDEASSQTD--LSQTISKKTVRSIQEAPVSEDLVIRLRRPPLRYP 201
P RR R+ EE+E + + L + K+ + ++ E+ V + LR
Sbjct: 1098 PEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREE 1157
Query: 202 RYEATSVQQKVNFSEEGETEEDDQ 225
+ + + + EE E +++++
Sbjct: 1158 PEKRRRQELERQYREEEELQQEEE 1181
Score = 38.9 bits (89), Expect = 0.013
Identities = 38/157 (24%), Positives = 73/157 (46%), Gaps = 8/157 (5%)
Query: 71 EPLVAKERSPVGKRTRLEEFRSDSAKEEVRESAYYLRSRQRRQPRPQETEEMKTRRTTRL 130
E L +ER KR R E+ R +E++++ L +R + R QE E + R+ +L
Sbjct: 911 EELQREERE---KRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERER-QYRKDKKL 966
Query: 131 QQQHSEQPPLQPSPVMTRRGLRDSHSSEEDEASSQTD--LSQTISKKTVRSIQEAPVSED 188
QQ+ E+ L P RR R+ EE+E + + L + K+ + + +D
Sbjct: 967 QQK--EEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKD 1024
Query: 189 LVIRLRRPPLRYPRYEATSVQQKVNFSEEGETEEDDQ 225
+ + LR R + +++ + EE E +++++
Sbjct: 1025 ELQQEEEQLLREEREKRRLQERERQYREEEELQQEEE 1061
Score = 35.4 bits (80), Expect = 0.15
Identities = 42/177 (23%), Positives = 73/177 (41%), Gaps = 10/177 (5%)
Query: 55 REVRFSDEPPEVYGDFEPLVAKE----RSPVGKRTRLEEFRSDSAKEEVRESAYYLRSRQ 110
RE R E Y E L +E R KR R E R +EE+++ L R+
Sbjct: 1068 RETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLL-RE 1126
Query: 111 RRQPRPQETEEMKTRRTTRLQQQHSEQPPLQPSPVMTRRGLRDSHSSEEDEASSQTDLSQ 170
R+ R ++ E + R +QQ+ E+ L+ P RR + EE+E + +
Sbjct: 1127 EREKRRRQELERQYREEEEVQQE--EEQLLREEPEKRRRQELERQYREEEELQQEEEQLL 1184
Query: 171 TISKKTVRSIQEAPVSEDLVIRLRRPPLRYPRYEATSVQQKVNFSEEGETEEDDQDS 227
++ R +E E+ ++ ++ R RY + + + E E E +D+
Sbjct: 1185 REEQEKRRQERERQYREEEELQRQK---RKQRYRDEDQRSDLKWQWEPEKENAVRDN 1238
Score = 34.3 bits (77), Expect = 0.32
Identities = 35/118 (29%), Positives = 50/118 (42%), Gaps = 7/118 (5%)
Query: 48 PPSRQGRREVRFSDEPPEVYGDFEPLVAKERSPVGKRTRLEEFRSDSAKEEVRESAYYLR 107
P R+ + R E E+ + E L+ +ER KR R E R +EEV++ L
Sbjct: 1098 PEKRRRQERERQCREEEELQQEEEQLLREERE---KRRRQELERQYREEEEVQQEEEQLL 1154
Query: 108 SRQRRQPRPQETEEMKTRRTTRLQQQHSEQPPLQPSPVMTRRGLRDSHSSEEDEASSQ 165
+ + R QE E + R LQQ E+ L RR R+ EE+E Q
Sbjct: 1155 REEPEKRRRQELER-QYREEEELQQ---EEEQLLREEQEKRRQERERQYREEEELQRQ 1208
Score = 32.0 bits (71), Expect = 1.6
Identities = 49/201 (24%), Positives = 78/201 (38%), Gaps = 26/201 (12%)
Query: 86 RLEEFRSDSA---KEEVRESAYYLRSRQRRQPR-PQETEE-----MKTRRTTRL-QQQHS 135
RLE+ R + ++E R R +RRQ R +E EE +K RL Q++
Sbjct: 557 RLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERR 616
Query: 136 EQPPLQPSPVMTRRGLRDSHSSEEDEASSQTDLSQTISKKTVRSIQEAPVSEDLVIRLRR 195
EQ + P RR + SEE E Q L + ++ + ++ E L RL+R
Sbjct: 617 EQRLKREEPEEERR--QQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKR 674
Query: 196 PPLRYPRYEATSVQQKVNFSE-----------EGETEEDDQDSSHSSVTTVKARSRDSDE 244
R + + +++ E + E+E D + S S + R E
Sbjct: 675 EHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQE 734
Query: 245 SGDKTTRSSSQYIESFWQSSQ 265
+K R S E WQ +
Sbjct: 735 QEEKRRRRES---ELQWQEEE 752
Score = 30.8 bits (68), Expect = 3.6
Identities = 29/160 (18%), Positives = 65/160 (40%), Gaps = 13/160 (8%)
Query: 51 RQGRREVRFSDEPPEVYGDFEPLVAKERSPVGKRTRLEEFRSDSAKEEVRESAYYLRSRQ 110
R+ R++ F +E + + E ++ KE + + E R +EE + R
Sbjct: 230 RRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEE---EPQRQRELQEEEEQLRKLERQEL 286
Query: 111 RRQPRPQETEEMKTRRTTRLQQQHSEQPPLQPSPVMTRRGLRDSHSSEEDEASSQTDLSQ 170
RR+ + +E ++ + RR +L+++ E+ RR ++ +++ Q + +
Sbjct: 287 RRERQEEEQQQQRLRREQQLRRKQEEE----------RREQQEERREQQERREQQEERRE 336
Query: 171 TISKKTVRSIQEAPVSEDLVIRLRRPPLRYPRYEATSVQQ 210
++ +E + + R LR + E QQ
Sbjct: 337 QQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQ 376
Score = 30.0 bits (66), Expect = 6.1
Identities = 37/183 (20%), Positives = 73/183 (39%), Gaps = 23/183 (12%)
Query: 51 RQGRREVRFSDEPPEVYGDFEPLVAKERSPVGKRTRLEEFRSDSAKEEVRESAY----YL 106
R+ + + R E ++ + E L+ +ER ++ R ++R D ++ E
Sbjct: 921 RRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEK 980
Query: 107 RSRQRRQPRPQETEEM------------KTRRTTRLQQQHSEQPPLQPSPVMTRRGLRDS 154
R RQ R+ + +E EE+ + RR ++Q+ ++ LQ R R+
Sbjct: 981 RRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREK 1040
Query: 155 HSSEEDEASSQTDLSQTISKKTVRSIQEAPVSEDLVIRLRRPPLRYPRYEATSVQQKVNF 214
+E E Q ++ ++ +E + E+ R R+ R R E Q++
Sbjct: 1041 RRLQERE-------RQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQL 1093
Query: 215 SEE 217
E
Sbjct: 1094 LRE 1096
Score = 29.6 bits (65), Expect = 8.0
Identities = 52/273 (19%), Positives = 98/273 (35%), Gaps = 21/273 (7%)
Query: 76 KERSPVGKRTRLEEFRSDSAKEEVRESAYYLRSRQRRQPRPQETEE----MKTRRTTRLQ 131
+ER R EE R K + E R R +Q R ++ E +K RL+
Sbjct: 500 QERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLE 559
Query: 132 QQHSEQPPLQPSPVMTRRGLRDSHSSEEDEASSQTD--LSQTISKKTVRSIQEAPVSEDL 189
Q+ EQ + + L+ + + + L Q + ++ V +++ E
Sbjct: 560 QERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQR 619
Query: 190 VIR-----LRRPPLRYPRYEATSVQQKVNFSEEGETE-----EDDQDSSHSSVTTVKARS 239
+ R RR L + QQ++ ++ E E++++ +
Sbjct: 620 LKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEE 679
Query: 240 RDSDESGDKTTRSSSQYIESFWQSSQSQNFTAHDKQPSVLSSGYQKTPQEWAPQTARIRT 299
R E ++ + + I+S Q Q + D + S + S +K + Q +
Sbjct: 680 RREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKR 739
Query: 300 RMQNDSILKSELGNQSPSTSSRQVTGQPQNASF 332
R + +SEL Q + RQ + Q F
Sbjct: 740 RRR-----ESELQWQEEERAHRQQQEEEQRRDF 767
>gi|4759208 TAO kinase 2 isoform 1 [Homo sapiens]
Length = 1049
Score = 40.4 bits (93), Expect = 0.005
Identities = 27/98 (27%), Positives = 49/98 (50%), Gaps = 1/98 (1%)
Query: 374 QLKNKYQGQDEKLWKRSQTFLEKHLNSSHPRSQPAILLLTAARDAEEALRCLSEQIADAY 433
Q+K ++Q + K+ R L HL + P++Q LL + L L+EQ +
Sbjct: 749 QIKKQFQ-ETCKIQTRQYKALRAHLLETTPKAQHKSLLKRLKEEQTRKLAILAEQYDQSI 807
Query: 434 SSFRSVRAIRIDGTDKATQDSDTVKLEVDQELSNGFKN 471
S S +A+R+D T +A + +L+ + EL N +++
Sbjct: 808 SEMLSSQALRLDETQEAEFQALRQQLQQELELLNAYQS 845
>gi|197209826 chromosome 2 open reading frame 21 isoform 1 [Homo
sapiens]
Length = 3258
Score = 40.0 bits (92), Expect = 0.006
Identities = 55/239 (23%), Positives = 93/239 (38%), Gaps = 20/239 (8%)
Query: 60 SDEPPEVYGDFEPLVAKERSPVGKRTRLEEFRSDSAKEEVRESAYYLRSRQRRQPRPQET 119
S P V D + L A+ G +R+ +S+ ++ + R R RQ R
Sbjct: 3018 SQSEPNVLDDSQGLAAE-----GSLSRVASIQSEPGQQNLLVQQPLGRKRGLRQLRRPLL 3072
Query: 120 EEMKTRRTTRLQQ-------QHSEQPPLQPSPVMTRRGLRDSHSSEEDEASSQTDLSQTI 172
KT+ R +Q + S QP +PS +R + + E A+ L T
Sbjct: 3073 SRQKTQTEPRNRQGARLSTTRRSIQPKTKPSADQ-KRSVTFIEAQPEPAAAPTDALPATG 3131
Query: 173 SKKTVRSI-QEAPVSEDLVIRLRRPPLRYPRYEATSVQQKVNF-SEEGETEEDDQDSSHS 230
+ P + D + P + + S +Q NF +EEGE EED + +
Sbjct: 3132 QLQGCSPAPSRKPEAMDEPVLTSSPAIVVADLHSVSPKQSENFPTEEGEKEEDTEAQGAT 3191
Query: 231 SVTTVKARSRDSDESGDKTTRSSSQYIESFWQSSQSQNFTAHDKQPSVLSSGYQKTPQE 289
+ + + A+ D D+ T S Q+ ++ S+ + +LSS + TP E
Sbjct: 3192 AHSPLSAQLSDPDDFTGLETSSLLQHGDTVLHISEENGM-----ENPLLSSQFTFTPTE 3245
>gi|45439370 TAO kinase 1 [Homo sapiens]
Length = 1001
Score = 39.3 bits (90), Expect = 0.010
Identities = 31/113 (27%), Positives = 52/113 (46%), Gaps = 8/113 (7%)
Query: 359 EVETTAVQEFQNQMNQLKNKY-----QGQDE-KLWKRSQTFLEKHLNSSHPRSQPAILLL 412
E+ V E + Q LK+K Q QD K+ R L HL + P+S+ +L
Sbjct: 699 ELRRKHVMEVRQQPKSLKSKELQIKKQFQDTCKIQTRQYKALRNHLLETTPKSEHKAVLK 758
Query: 413 TAARDAEEALRCLSEQIADAYSSFRSVRAIRIDGTDKATQDSDTVKLEVDQEL 465
+ L L+EQ + + S +A+R+D +A + +K+++ QEL
Sbjct: 759 RLKEEQTRKLAILAEQYDHSINEMLSTQALRLDEAQEA--ECQVLKMQLQQEL 809
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 39.3 bits (90), Expect = 0.010
Identities = 58/318 (18%), Positives = 122/318 (38%), Gaps = 27/318 (8%)
Query: 45 YRTPPSRQGRREVRFSDEPPEVYGDFE-----PLVAKERSPVGKRTRLEEFRSDS----- 94
YRTP + R R S+ PP + + + + ER G ++ L E + +
Sbjct: 341 YRTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVR 400
Query: 95 -AKEEVRESAYYLRSRQRRQPRPQETEEMKTRRTTRLQQQHSEQPPLQPSPVMTRRGLRD 153
+ ++ + S R+ + ++ ++ K+ R +++SE+ + V R +
Sbjct: 401 VKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKS 460
Query: 154 SHSSEEDEASSQTDLSQTIS-KKTVRSIQEAPVSEDLVIRLRRPPLRYPRYEATSVQQKV 212
S+E S + D + +K +RS + E++ + ++ + E + ++K
Sbjct: 461 RSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEK- 519
Query: 213 NFSEEGETEEDDQDSSHSSVTTVKARSRDSD-ESGDKTTRSSSQYIESFWQSSQSQNFTA 271
+ E ++ E D S ++RSR+ D G + S ++ S+
Sbjct: 520 SKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRT 579
Query: 272 HDKQPSVLSSGYQKTPQEW-------------APQTARIRTRMQNDSILKSELGNQSPST 318
HD+ S ++ QE+ P +R + R + +S +S S
Sbjct: 580 HDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSR 639
Query: 319 SSRQVTGQPQNASFVKRN 336
+ + Q +S K N
Sbjct: 640 NKDKYRNQESKSSHRKEN 657
Score = 37.4 bits (85), Expect = 0.038
Identities = 53/217 (24%), Positives = 80/217 (36%), Gaps = 44/217 (20%)
Query: 74 VAKERSPVGKRTRLEEFRSDSAKEEVRESAYYL-RSRQRRQPRPQETEEMKTRRTTRLQQ 132
+ K + RTR E RS VR + RSR + R +E E RR R +
Sbjct: 551 ITKGKHSYNSRTR-ERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEY---RRRGRSRS 606
Query: 133 QHSEQPPLQPSPVMTRRGLRDSHSSEEDEASSQTDLSQTISKKTVRSIQEAPVSEDLVIR 192
+ PP + RR RDS SSE +E+ S
Sbjct: 607 RERRTPPGRSRSKDRRRRRRDSRSSEREESQS---------------------------- 638
Query: 193 LRRPPLRYPRYEATSVQQKVNFSEEGETEEDDQDSSHSSVTTVKARSRDSDESGDKTTRS 252
R +Y E+ S +K N E E + H+S + + D D+S +
Sbjct: 639 --RNKDKYRNQESKSSHRKEN--SESEKRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQ 694
Query: 253 SSQYIESFWQSSQSQNFTAHDKQPSVLSSGYQKTPQE 289
SSQ ++ +SS +N K+ + S +K Q+
Sbjct: 695 SSQ--DNELKSSMLKN-----KEDEKIRSSVEKENQK 724
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 39.3 bits (90), Expect = 0.010
Identities = 34/140 (24%), Positives = 57/140 (40%), Gaps = 10/140 (7%)
Query: 21 PRAPIREGRGRLAPQNGGSSDAPAYRTP--PSRQGRREVRFSDEPPEVYGDFEPLVAKER 78
P P+R P + G S AP + P P + E S++PPE P A
Sbjct: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQ----TPETAMPE 1725
Query: 79 SPVGKR-TRLEEFRSDSAKEEVRESAYYLRSRQR---RQPRPQETEEMKTRRTTRLQQQH 134
P ++ + L + KE+V LR + RQ RP+ + T+RL +
Sbjct: 1726 PPAPEKPSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPATSRLPKAR 1785
Query: 135 SEQPPLQPSPVMTRRGLRDS 154
+ +P P ++ L+++
Sbjct: 1786 PTKVKAEPPPKKRKKWLKEA 1805
>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
8 [Homo sapiens]
Length = 780
Score = 38.9 bits (89), Expect = 0.013
Identities = 48/224 (21%), Positives = 79/224 (35%), Gaps = 23/224 (10%)
Query: 51 RQGRREVRFSDEPPEVYGDFEPLVAKERSPVGKRTRLEEFRSDSAKEEVRESAYYLRSRQ 110
RQ RRE+ E D L + ++ E + KE+ + R+ +
Sbjct: 139 RQKRREMAREHSRRERGNDGVCLFRDRLEQLERKRERERKMREQQKEQREQKERERRAEE 198
Query: 111 RRQPRPQETEEMKTRRTTR------LQQQHSEQPPLQPSPVMTRRGLRDSHSSEEDEASS 164
RR+ R E RT R ++ H + P P P R L D ++E
Sbjct: 199 RRKEREARREVSAHHRTMREDYSDKVKASHWSRSP--PRPPRERFELGDGRKPVKEEKME 256
Query: 165 QTDLSQTISKKTVRSIQEAPVSEDLVIRLRRPPLRYPRYEATSVQQKVNFSEEGETEEDD 224
+ DL + +Q+ SE R A S EE E EE++
Sbjct: 257 ERDL--------LSDLQDISDSE-------RKTSSAESSSAESGSGSEEEEEEEEEEEEE 301
Query: 225 QDSSHSSVTTVKARSRDSDESGDKTTRSSSQYIESFWQSSQSQN 268
+S S + + +E+G + +S Q E + S++
Sbjct: 302 GSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSED 345
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 38.5 bits (88), Expect = 0.017
Identities = 48/205 (23%), Positives = 90/205 (43%), Gaps = 13/205 (6%)
Query: 51 RQGRREVRFSDEPPEVYGDFEPLVAKERSPVGKRTRLEEFRSDSAKEEVRESAYYLRSRQ 110
R+ R R + E + E A+ER +R R E + D +++ RE +R +
Sbjct: 753 REERERERERERERERERERERERARERDKERERQRDWEDK-DKGRDDRREKREEIR--E 809
Query: 111 RRQPRPQETEEMKTRRTTRLQQQHSEQPPLQPSPVMTRRGLRDSHSSEEDEASSQTDLSQ 170
R PR +E K+++ R + + S P P D+++S +D+ LSQ
Sbjct: 810 DRNPRDGH-DERKSKK--RYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQ 866
Query: 171 TISKKTVRSIQEAPVSEDLVIRLR---RPPLRYP---RYEATSVQQKVNFSEEGETEEDD 224
+ + RS+ + ++ED R + R P R RYE +++KV+ ++ + +
Sbjct: 867 VVRPQESRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEI 926
Query: 225 QDSSHSSVTTVKARSRDSD-ESGDK 248
+SS + + D E+ D+
Sbjct: 927 LESSRMRAQDIIGHHQSEDRETSDR 951
Score = 30.4 bits (67), Expect = 4.7
Identities = 41/198 (20%), Positives = 72/198 (36%), Gaps = 13/198 (6%)
Query: 49 PSRQGRREVRFSDEPPEVYGDFEPLVAKER-----SPVGKRTRLEEFRSDSAKEEVRESA 103
P R R + R S +G+ + +ER SP+ + R +E D +EE R
Sbjct: 609 PERDNRDQARDSSFERR-HGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDR 667
Query: 104 YYLRSRQRRQPRPQETEEMKTRRTTRLQQQHSEQPPLQPSPVMTRRGLRDSHSSEEDEAS 163
R +R + R +E E + R R +++ E+ + + R R+ E E
Sbjct: 668 VDDRRDERARERDRERERDRERERERERERDRER---EKERELERERAREREREREKERD 724
Query: 164 SQTDLSQTISKKTVRSIQEAPVSEDLVIRLRRPPLRYPRYEATSVQQKVNFSEEGETEED 223
+ D + ++ R + E R R R E +++ E E
Sbjct: 725 RERDRDRDHDRERERERERDREKE----REREREERERERERERERERERERERERARER 780
Query: 224 DQDSSHSSVTTVKARSRD 241
D++ K + RD
Sbjct: 781 DKERERQRDWEDKDKGRD 798
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 38.1 bits (87), Expect = 0.023
Identities = 32/160 (20%), Positives = 62/160 (38%), Gaps = 4/160 (2%)
Query: 11 VREGWGVYVTPRAPIREGRGRLAPQNGGSSDAPAYRTPPSRQGRREVRFSDEPPEVYGDF 70
VRE G +RE G++ Q G + Q + + E G+
Sbjct: 166 VREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQ 225
Query: 71 EPLVAKERSPVG---KRTRLEEFRSDSAKEEVRESAYYLRSRQRRQPRPQETEEMKTRRT 127
E + K+ +G ++ + +E + +E++R+ +R Q Q R QE + +K +
Sbjct: 226 EEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMR-EQEEQMREQEEQMLKQKEQ 284
Query: 128 TRLQQQHSEQPPLQPSPVMTRRGLRDSHSSEEDEASSQTD 167
T ++Q EQ R + +E++ Q +
Sbjct: 285 TEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEE 324
>gi|226958575 RAS protein activator like 2 isoform 2 [Homo sapiens]
Length = 1280
Score = 37.7 bits (86), Expect = 0.029
Identities = 45/190 (23%), Positives = 75/190 (39%), Gaps = 25/190 (13%)
Query: 112 RQPRPQETEEMKTRRTTRLQQQHSEQP-----------PLQPSPVMTRRGLRDSHSSEED 160
+ P T+ +T L QQ S Q L ++ L+D+H+++ +
Sbjct: 803 KSPSQDNTDSYFRGKTLLLVQQASSQSMTYSEKDERESSLPNGRSVSLMDLQDTHAAQVE 862
Query: 161 EAS-----------SQTDLSQTISKKTVRSIQEAPVSEDLVIRLRRPPLRYPR-YEATSV 208
AS SQ ++Q S K +R Q P S V R P L P + S
Sbjct: 863 HASVMLDVPIRLTGSQLSITQVASIKQLRETQSTPQSAPQVRRPLHPALNQPGGLQPLSF 922
Query: 209 QQKVNFSEEG--ETEEDDQDSSHSSVTTVKARSRDSDESGDKTTRSSSQYIESFWQSSQS 266
Q V + DSS +++T +RS+ + E + S+S + +S+QS
Sbjct: 923 QNPVYHLNNPIPAMPKASIDSSLENLSTASSRSQSNSEDFKLSGPSNSSMEDFTKRSTQS 982
Query: 267 QNFTAHDKQP 276
++F+ P
Sbjct: 983 EDFSRRHTVP 992
>gi|4758808 RAS protein activator like 2 isoform 1 [Homo sapiens]
Length = 1139
Score = 37.7 bits (86), Expect = 0.029
Identities = 45/190 (23%), Positives = 75/190 (39%), Gaps = 25/190 (13%)
Query: 112 RQPRPQETEEMKTRRTTRLQQQHSEQP-----------PLQPSPVMTRRGLRDSHSSEED 160
+ P T+ +T L QQ S Q L ++ L+D+H+++ +
Sbjct: 662 KSPSQDNTDSYFRGKTLLLVQQASSQSMTYSEKDERESSLPNGRSVSLMDLQDTHAAQVE 721
Query: 161 EAS-----------SQTDLSQTISKKTVRSIQEAPVSEDLVIRLRRPPLRYPR-YEATSV 208
AS SQ ++Q S K +R Q P S V R P L P + S
Sbjct: 722 HASVMLDVPIRLTGSQLSITQVASIKQLRETQSTPQSAPQVRRPLHPALNQPGGLQPLSF 781
Query: 209 QQKVNFSEEG--ETEEDDQDSSHSSVTTVKARSRDSDESGDKTTRSSSQYIESFWQSSQS 266
Q V + DSS +++T +RS+ + E + S+S + +S+QS
Sbjct: 782 QNPVYHLNNPIPAMPKASIDSSLENLSTASSRSQSNSEDFKLSGPSNSSMEDFTKRSTQS 841
Query: 267 QNFTAHDKQP 276
++F+ P
Sbjct: 842 EDFSRRHTVP 851
>gi|195927037 DNA (cytosine-5-)-methyltransferase 1 isoform a [Homo
sapiens]
Length = 1632
Score = 37.7 bits (86), Expect = 0.029
Identities = 47/246 (19%), Positives = 89/246 (36%), Gaps = 33/246 (13%)
Query: 3 GDGRRAEAVREGWGVYVTPRAPIREGRGRLAPQNGGSSDAPAYRTPPSRQGRREVRFSDE 62
G+ R+EA R G +P P+ + R ++ G +A R PP+ + +
Sbjct: 110 GNQARSEARRVGMADANSPPKPLSKPRTPRRSKSDG--EAKRSRDPPAS--------ASQ 159
Query: 63 PPEVYGDFEPLVAKERSPVGKRTRLEEFRSDSAKEEVRESAYYLRSRQRRQPRPQETEEM 122
+ + P R + T F AK + +E + +S + + ++ +E
Sbjct: 160 VTGIRAEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEK 219
Query: 123 KTRRTTRLQQQHSEQPPLQPSPVMTRRGLRDSHSSEEDEASSQTDLSQTISKKTVRSIQE 182
+ R T+R + +P P + G R E DE + SQT + ++E
Sbjct: 220 RRRVTSR---ERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKE 276
Query: 183 APVSEDLVIRLRRPPLRYPRYEATSVQQKVNFSEEGETEEDDQDSSHSSVTTVKARSRDS 242
P E + V E+ + +E D+ S + A+ R
Sbjct: 277 EPDRE--------------------ARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPE 316
Query: 243 DESGDK 248
++ +K
Sbjct: 317 EKEPEK 322
>gi|34878777 ring finger protein 20 [Homo sapiens]
Length = 975
Score = 37.4 bits (85), Expect = 0.038
Identities = 40/185 (21%), Positives = 77/185 (41%), Gaps = 17/185 (9%)
Query: 61 DEPPEVYGDFEPLVAKERSPVGKRTRLEEFRSDSAKEEVRESAYYLRSRQRRQ-PRPQET 119
DEP E+ D E L ++ + + E +S +EE R R+RR+ R +E
Sbjct: 531 DEPAELKPDSEDLSSQSSASKASQEDANEIKSKRDEEE--------RERERREKERERER 582
Query: 120 EEMKTRRTTRLQQQHSEQPPLQPSPVMTRRGLRDSHSSEEDEASSQTDL-------SQTI 172
E K + R +Q+ E + S +G D +E E Q + SQ
Sbjct: 583 EREKEKEREREKQKLKESEKERDSAKDKEKGKHDDGRKKEAEIIKQLKIELKKAQESQKE 642
Query: 173 SKKTVRSIQEAPVSEDLVIRLRRPPLRYPRYEATSVQQKVNFSEEGETEEDDQDSSHSSV 232
K + + AP + ++L + + E ++Q++ E+ E +E+ + + ++
Sbjct: 643 MKLLLDMYRSAPKEQRDKVQLMAAE-KKSKAELEDLRQRLKDLEDKEKKENKKMADEDAL 701
Query: 233 TTVKA 237
++A
Sbjct: 702 RKIRA 706
>gi|47578107 delangin isoform B [Homo sapiens]
Length = 2697
Score = 37.4 bits (85), Expect = 0.038
Identities = 34/177 (19%), Positives = 70/177 (39%), Gaps = 5/177 (2%)
Query: 132 QQHSEQPPLQPSPVMTRRGLRDSHSSEEDEASSQTDLSQTISKKTVRSIQEAPVSEDLVI 191
+ H E P + P +++ ++ S S + ++ L +T S + + +E+L
Sbjct: 594 ENHPETPKKKSDPELSKSEMKQSESRLAESKPNENRLVETKSSENKLETKVETQTEELKQ 653
Query: 192 RLRRPPLRYPRYEATSVQQKVNFSEEGETEEDDQDSSHSSVTTVKARSRDSDESGDKTTR 251
R + E+T V+ K N + +T+ +D ++ T K+R + G+
Sbjct: 654 NESRTT-ECKQNESTIVEPKQNENRLSDTKPNDNKQNNGRSETTKSRPETPKQKGESRPE 712
Query: 252 SSSQYIESFWQSSQSQNFTAHDKQPSVLSSGYQKTPQ---EWAPQTARIRTRMQNDS 305
+ Q + + Q + P +TP+ E P+T + R + DS
Sbjct: 713 TPKQKSDGH-PETPKQKGDGRPETPKQKGESRPETPKQKNEGRPETPKHRHDNRRDS 768
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.126 0.359
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,802,929
Number of Sequences: 37866
Number of extensions: 1084192
Number of successful extensions: 5281
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 38
Number of HSP's successfully gapped in prelim test: 281
Number of HSP's that attempted gapping in prelim test: 4747
Number of HSP's gapped (non-prelim): 720
length of query: 583
length of database: 18,247,518
effective HSP length: 108
effective length of query: 475
effective length of database: 14,157,990
effective search space: 6725045250
effective search space used: 6725045250
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.