Guide to the Human Genome
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Search of human proteins with 39725952

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|39725952 angiogenic factor VG5Q [Homo sapiens]
         (714 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|39725952 angiogenic factor VG5Q [Homo sapiens]                    1452   0.0  
gi|5032031 RNA binding motif protein 5 [Homo sapiens]                  66   1e-10
gi|20127479 RNA binding motif protein 10 isoform 1 [Homo sapiens]      59   2e-08
gi|23111018 RNA binding motif protein 10 isoform 2 [Homo sapiens]      59   2e-08
gi|167900474 coiled-coil domain containing 75 [Homo sapiens]           53   1e-06
gi|8922313 G patch domain containing 2 [Homo sapiens]                  51   3e-06
gi|148747556 PIN2-interacting protein 1 [Homo sapiens]                 50   7e-06
gi|224282119 splicing factor, arginine/serine-rich 14 [Homo sapi...    49   1e-05
gi|224282117 splicing factor, arginine/serine-rich 14 [Homo sapi...    49   1e-05
gi|33469964 splicing factor 4 [Homo sapiens]                           48   4e-05
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    47   8e-05
gi|63003897 transcription factor NRF [Homo sapiens]                    47   8e-05
gi|4758648 kinesin family member 5B [Homo sapiens]                     45   3e-04
gi|50658069 phosphodiesterase 4D interacting protein isoform 2 [...    44   4e-04
gi|50658071 phosphodiesterase 4D interacting protein isoform 5 [...    44   4e-04
gi|157311604 phosphodiesterase 4D interacting protein isoform 1 ...    44   4e-04
gi|87299628 biorientation of chromosomes in cell division 1-like...    43   0.001
gi|50962882 G patch domain containing 8 [Homo sapiens]                 42   0.002
gi|38045919 huntingtin interacting protein 1 [Homo sapiens]            42   0.003
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]     41   0.003
gi|119226260 calcium homeostasis endoplasmic reticulum protein [...    41   0.003
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]     41   0.004
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]     41   0.004
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof...    41   0.004
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof...    41   0.004
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof...    41   0.004
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof...    41   0.004
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]           40   0.006
gi|58535453 CDK5 regulatory subunit associated protein 2 isoform...    40   0.008
gi|58535451 CDK5 regulatory subunit associated protein 2 isoform...    40   0.008

>gi|39725952 angiogenic factor VG5Q [Homo sapiens]
          Length = 714

 Score = 1452 bits (3758), Expect = 0.0
 Identities = 714/714 (100%), Positives = 714/714 (100%)

Query: 1   MASEAPSPPRSPPPPTSPEPELAQLRRKVEKLERELRSCKRQVREIEKLLHHTERLYQNA 60
           MASEAPSPPRSPPPPTSPEPELAQLRRKVEKLERELRSCKRQVREIEKLLHHTERLYQNA
Sbjct: 1   MASEAPSPPRSPPPPTSPEPELAQLRRKVEKLERELRSCKRQVREIEKLLHHTERLYQNA 60

Query: 61  ESNNQELRTQVEELSKILQRGRNEDNKKSDVEVQTENHAPWSISDYFYQTYYNDVSLPNK 120
           ESNNQELRTQVEELSKILQRGRNEDNKKSDVEVQTENHAPWSISDYFYQTYYNDVSLPNK
Sbjct: 61  ESNNQELRTQVEELSKILQRGRNEDNKKSDVEVQTENHAPWSISDYFYQTYYNDVSLPNK 120

Query: 121 VTELSDQQDQAIETSILNSKDHLQVENDAYPGTDRTENVKYRQVDHFASNSQEPASALAT 180
           VTELSDQQDQAIETSILNSKDHLQVENDAYPGTDRTENVKYRQVDHFASNSQEPASALAT
Sbjct: 121 VTELSDQQDQAIETSILNSKDHLQVENDAYPGTDRTENVKYRQVDHFASNSQEPASALAT 180

Query: 181 EDTSLEGSSLAESLRAAAEAAVSQTGFSYDENTGLYFDHSTGFYYDSENQLYYDPSTGIY 240
           EDTSLEGSSLAESLRAAAEAAVSQTGFSYDENTGLYFDHSTGFYYDSENQLYYDPSTGIY
Sbjct: 181 EDTSLEGSSLAESLRAAAEAAVSQTGFSYDENTGLYFDHSTGFYYDSENQLYYDPSTGIY 240

Query: 241 YYCDVESGRYQFHSRVDLQPYPTSSTKQSKDKKLKKKRKDPDSSATNEEKDLNSEDQKAF 300
           YYCDVESGRYQFHSRVDLQPYPTSSTKQSKDKKLKKKRKDPDSSATNEEKDLNSEDQKAF
Sbjct: 241 YYCDVESGRYQFHSRVDLQPYPTSSTKQSKDKKLKKKRKDPDSSATNEEKDLNSEDQKAF 300

Query: 301 SVEHTSCNEEENFANMKKKAKIGIHHKNSPPKVTVPTSGNTIESPLHENISNSTSFKDEK 360
           SVEHTSCNEEENFANMKKKAKIGIHHKNSPPKVTVPTSGNTIESPLHENISNSTSFKDEK
Sbjct: 301 SVEHTSCNEEENFANMKKKAKIGIHHKNSPPKVTVPTSGNTIESPLHENISNSTSFKDEK 360

Query: 361 IMETDSEPEEGEITDSQTEDSYDEAITSEGNVTAEDSEDEDEDKIWPPCIRVIVIRSPVL 420
           IMETDSEPEEGEITDSQTEDSYDEAITSEGNVTAEDSEDEDEDKIWPPCIRVIVIRSPVL
Sbjct: 361 IMETDSEPEEGEITDSQTEDSYDEAITSEGNVTAEDSEDEDEDKIWPPCIRVIVIRSPVL 420

Query: 421 QIGSLFIITAVNPATIGREKDMEHTLRIPEVGVSKFHAEIYFDHDLQSYVLVDQGSQNGT 480
           QIGSLFIITAVNPATIGREKDMEHTLRIPEVGVSKFHAEIYFDHDLQSYVLVDQGSQNGT
Sbjct: 421 QIGSLFIITAVNPATIGREKDMEHTLRIPEVGVSKFHAEIYFDHDLQSYVLVDQGSQNGT 480

Query: 481 IVNGKQILQPKTKCDPYVLEHGDEVKIGETVLSFHIHPGSDTCDGCEPGQVRAHLRLDKK 540
           IVNGKQILQPKTKCDPYVLEHGDEVKIGETVLSFHIHPGSDTCDGCEPGQVRAHLRLDKK
Sbjct: 481 IVNGKQILQPKTKCDPYVLEHGDEVKIGETVLSFHIHPGSDTCDGCEPGQVRAHLRLDKK 540

Query: 541 DESFVGPTLSKEEKELERRKELKKIRVKYGLQNTEYEDEKTLKNPKYKDRAGKRREQVGS 600
           DESFVGPTLSKEEKELERRKELKKIRVKYGLQNTEYEDEKTLKNPKYKDRAGKRREQVGS
Sbjct: 541 DESFVGPTLSKEEKELERRKELKKIRVKYGLQNTEYEDEKTLKNPKYKDRAGKRREQVGS 600

Query: 601 EGTFQRDDAPASVHSEITDSNKGRKMLEKMGWKKGEGLGKDGGGMKTPIQLQLRRTHAGL 660
           EGTFQRDDAPASVHSEITDSNKGRKMLEKMGWKKGEGLGKDGGGMKTPIQLQLRRTHAGL
Sbjct: 601 EGTFQRDDAPASVHSEITDSNKGRKMLEKMGWKKGEGLGKDGGGMKTPIQLQLRRTHAGL 660

Query: 661 GTGKPSSFEDVHLLQNKNKKNWDKARERFTENFPETKPQKDDPGTMPWVKGTLE 714
           GTGKPSSFEDVHLLQNKNKKNWDKARERFTENFPETKPQKDDPGTMPWVKGTLE
Sbjct: 661 GTGKPSSFEDVHLLQNKNKKNWDKARERFTENFPETKPQKDDPGTMPWVKGTLE 714


>gi|5032031 RNA binding motif protein 5 [Homo sapiens]
          Length = 815

 Score = 65.9 bits (159), Expect = 1e-10
 Identities = 61/230 (26%), Positives = 90/230 (39%), Gaps = 25/230 (10%)

Query: 161 YRQVDHFASNSQEPASALATEDTSLEGSSLAESLRAAAEAAVSQTGFSYDENTGLYFDHS 220
           Y Q  +   +  E A    +  T    +S    +     A    + + YDE++G Y+D +
Sbjct: 416 YNQTSNPPGSPTEEAQPSTSTSTQAPAASPTGVVPGTKYAVPDTSTYQYDESSGYYYDPT 475

Query: 221 TGFYYDSENQLYYDPSTGIYYYCDVESGRY------QFHSRVDLQPYPTSSTKQSKDKKL 274
           TG YYD  +Q YY+  T  Y Y D E   Y        H +  L P      K+ K+KK 
Sbjct: 476 TGLYYDPNSQYYYNSLTQQYLYWDGEKETYVPAAESSSHQQSGLPP-----AKEGKEKKE 530

Query: 275 KKKRKDPDSSATNEE---KDLN--SEDQKAFSVEHTSCNEEE---------NFANMKKKA 320
           K K K     A + E   K LN   E+ K       S  EEE          FA  +KK 
Sbjct: 531 KPKSKTAQQIAKDMERWAKSLNKQKENFKNSFQPVNSLREEERRESAAADAGFALFEKKG 590

Query: 321 KIGIHHKNSPPKVTVPTSGNTIESPLHENISNSTSFKDEKIMETDSEPEE 370
            +    +  P  V      N ++  L    S  +  ++E +   +SE E+
Sbjct: 591 ALAERQQLIPELVRNGDEENPLKRGLVAAYSGDSDNEEELVERLESEEEK 640



 Score = 59.7 bits (143), Expect = 9e-09
 Identities = 43/123 (34%), Positives = 64/123 (52%), Gaps = 18/123 (14%)

Query: 549 LSKEEKELERRKELKKIRVKYGLQNTEYEDEKTLKNPKYKDRAGKRREQVG----SEGTF 604
           L K+  ++ RR  L +  ++  L+  E E        KY+DRA +RRE+ G     E   
Sbjct: 671 LHKQNMDIYRRSRLSEQELE-ALELRERE-------MKYRDRAAERREKYGIPEPPEPKR 722

Query: 605 QRDDAPASVHSE------ITDSNKGRKMLEKMGWKKGEGLGKDGGGMKTPIQLQLRRTHA 658
           ++     +V+ E      I  SN G KML+ MGW++G GLG+   G+  PI+ Q+R   A
Sbjct: 723 KKQFDAGTVNYEQPTKDGIDHSNIGNKMLQAMGWREGSGLGRKCQGITAPIEAQVRLKGA 782

Query: 659 GLG 661
           GLG
Sbjct: 783 GLG 785


>gi|20127479 RNA binding motif protein 10 isoform 1 [Homo sapiens]
          Length = 930

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 41/125 (32%), Positives = 61/125 (48%), Gaps = 19/125 (15%)

Query: 549 LSKEEKELERRKELKKIRVKYGLQNTEYEDEKTLKNPKYKDRAGKRREQVGSEGTFQRDD 608
           L K+  E+ RR  L +          E  ++  ++  KY+DRA +RRE+ G     +   
Sbjct: 783 LHKQNLEIHRRAHLSE-------NELEALEKNDMEQMKYRDRAAERREKYGIPEPPEPKR 835

Query: 609 ------APASVHSE------ITDSNKGRKMLEKMGWKKGEGLGKDGGGMKTPIQLQLRRT 656
                 + ASV  E      +   N G +ML+ MGWK+G GLG+   G+ TPI+ Q R  
Sbjct: 836 RKYGGISTASVDFEQPTRDGLGSDNIGSRMLQAMGWKEGSGLGRKKQGIVTPIEAQTRVR 895

Query: 657 HAGLG 661
            +GLG
Sbjct: 896 GSGLG 900



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 39/136 (28%), Positives = 60/136 (44%), Gaps = 19/136 (13%)

Query: 188 SSLAESLRAAAEAAVSQ------TGFSYDENTGLYFDHSTGFYYDSENQLYYDPSTGIYY 241
           S+L  +    A+ + SQ      + + YDE +G Y+D  TG YYD  +Q YY+  +  Y 
Sbjct: 547 SALPPATSPTAQESYSQYPVPDVSTYQYDETSGYYYDPQTGLYYDPNSQYYYNAQSQQYL 606

Query: 242 YCDVESGRY--QFHSRVDLQPYPTSSTKQSKDKKLKKKRKDPDSSATNEEKDLNSEDQKA 299
           Y D E   Y        D      + +K+ K+KK K K K     A + E+   S ++  
Sbjct: 607 YWDGERRTYVPALEQSADGHKETGAPSKEGKEKKEKHKTKTAQQIAKDMERWARSLNK-- 664

Query: 300 FSVEHTSCNEEENFAN 315
                    ++ENF N
Sbjct: 665 ---------QKENFKN 671


>gi|23111018 RNA binding motif protein 10 isoform 2 [Homo sapiens]
          Length = 852

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 41/125 (32%), Positives = 61/125 (48%), Gaps = 19/125 (15%)

Query: 549 LSKEEKELERRKELKKIRVKYGLQNTEYEDEKTLKNPKYKDRAGKRREQVGSEGTFQRDD 608
           L K+  E+ RR  L +          E  ++  ++  KY+DRA +RRE+ G     +   
Sbjct: 705 LHKQNLEIHRRAHLSE-------NELEALEKNDMEQMKYRDRAAERREKYGIPEPPEPKR 757

Query: 609 ------APASVHSE------ITDSNKGRKMLEKMGWKKGEGLGKDGGGMKTPIQLQLRRT 656
                 + ASV  E      +   N G +ML+ MGWK+G GLG+   G+ TPI+ Q R  
Sbjct: 758 RKYGGISTASVDFEQPTRDGLGSDNIGSRMLQAMGWKEGSGLGRKKQGIVTPIEAQTRVR 817

Query: 657 HAGLG 661
            +GLG
Sbjct: 818 GSGLG 822



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 39/136 (28%), Positives = 60/136 (44%), Gaps = 19/136 (13%)

Query: 188 SSLAESLRAAAEAAVSQ------TGFSYDENTGLYFDHSTGFYYDSENQLYYDPSTGIYY 241
           S+L  +    A+ + SQ      + + YDE +G Y+D  TG YYD  +Q YY+  +  Y 
Sbjct: 469 SALPPATSPTAQESYSQYPVPDVSTYQYDETSGYYYDPQTGLYYDPNSQYYYNAQSQQYL 528

Query: 242 YCDVESGRY--QFHSRVDLQPYPTSSTKQSKDKKLKKKRKDPDSSATNEEKDLNSEDQKA 299
           Y D E   Y        D      + +K+ K+KK K K K     A + E+   S ++  
Sbjct: 529 YWDGERRTYVPALEQSADGHKETGAPSKEGKEKKEKHKTKTAQQIAKDMERWARSLNK-- 586

Query: 300 FSVEHTSCNEEENFAN 315
                    ++ENF N
Sbjct: 587 ---------QKENFKN 593


>gi|167900474 coiled-coil domain containing 75 [Homo sapiens]
          Length = 259

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 39/138 (28%), Positives = 64/138 (46%), Gaps = 4/138 (2%)

Query: 567 VKYGLQNTEYEDEKTLKNPKYKDRAGKRREQVGSEGTFQRDDAPASVHSEITDSNKGRKM 626
           ++ GL       E   K  K ++   K R++   E   +R D    + + +   NKG  +
Sbjct: 19  IRPGLPMLRQIREARRKEEKQQEANLKNRQKSLKEEEQERRDI--GLKNALGCENKGFAL 76

Query: 627 LEKMGWKKGEGLGKDGGGMKTPIQLQLRRTHAGLGTGKPSSFEDVHLLQNKNKK--NWDK 684
           L+KMG+K G+ LGK GGG+  PI L ++   +G+G       +    L++  KK    ++
Sbjct: 77  LQKMGYKSGQALGKSGGGIVEPIPLNIKTGKSGIGHEASLKRKAEEKLESYRKKIHMKNQ 136

Query: 685 ARERFTENFPETKPQKDD 702
           A E+  E F      K D
Sbjct: 137 AEEKAAEQFRMRLKNKQD 154


>gi|8922313 G patch domain containing 2 [Homo sapiens]
          Length = 528

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 24/51 (47%), Positives = 30/51 (58%)

Query: 617 ITDSNKGRKMLEKMGWKKGEGLGKDGGGMKTPIQLQLRRTHAGLGTGKPSS 667
           I ++N G +ML+ MGW  G GLG+DG G+  PIQ   R    GLG   P S
Sbjct: 465 ILENNIGNRMLQNMGWTPGSGLGRDGKGISEPIQAMQRPKGLGLGFPLPKS 515


>gi|148747556 PIN2-interacting protein 1 [Homo sapiens]
          Length = 328

 Score = 50.1 bits (118), Expect = 7e-06
 Identities = 22/43 (51%), Positives = 29/43 (67%)

Query: 619 DSNKGRKMLEKMGWKKGEGLGKDGGGMKTPIQLQLRRTHAGLG 661
           DS  G++MLEKMGW KG+GLG    G    I++Q++  H GLG
Sbjct: 26  DSKFGQRMLEKMGWSKGKGLGAQEQGATDHIKVQVKNNHLGLG 68


>gi|224282119 splicing factor, arginine/serine-rich 14 [Homo sapiens]
          Length = 1082

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 23/55 (41%), Positives = 32/55 (58%)

Query: 616  EITDSNKGRKMLEKMGWKKGEGLGKDGGGMKTPIQLQLRRTHAGLGTGKPSSFED 670
            ++TD N G +ML+KMGWK+G GLG  G G++ P+ +       GLG       ED
Sbjct: 1008 KLTDKNLGFQMLQKMGWKEGHGLGSLGKGIREPVSVGTPSEGEGLGADGQEHKED 1062


>gi|224282117 splicing factor, arginine/serine-rich 14 [Homo sapiens]
          Length = 1082

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 23/55 (41%), Positives = 32/55 (58%)

Query: 616  EITDSNKGRKMLEKMGWKKGEGLGKDGGGMKTPIQLQLRRTHAGLGTGKPSSFED 670
            ++TD N G +ML+KMGWK+G GLG  G G++ P+ +       GLG       ED
Sbjct: 1008 KLTDKNLGFQMLQKMGWKEGHGLGSLGKGIREPVSVGTPSEGEGLGADGQEHKED 1062


>gi|33469964 splicing factor 4 [Homo sapiens]
          Length = 645

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 23/52 (44%), Positives = 32/52 (61%), Gaps = 1/52 (1%)

Query: 616 EITDSNKGRKMLEKMGWKKGEGLGKDGGGMKTPIQLQLRRTH-AGLGTGKPS 666
           ++T  N G +ML KMGWK+GEGLG +G G+K P+         AG G  +P+
Sbjct: 559 KLTVENIGYQMLMKMGWKEGEGLGSEGQGIKNPVNKGTTTVDGAGFGIDRPA 610


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 46.6 bits (109), Expect = 8e-05
 Identities = 62/319 (19%), Positives = 121/319 (37%), Gaps = 33/319 (10%)

Query: 83   NEDNKKSDVEVQTENHAPWSISDYFYQTYYNDVSLPNKVTELSDQQDQAIETSILNSKDH 142
            ++ +  SD    + +      SD    +  +D S  +  ++ SD  D +  +   NS D 
Sbjct: 726  SDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSD- 784

Query: 143  LQVENDAYPGTDRTENVKYRQVDHFASNSQEPASALATEDTSLEGSSLAESLRAAAEAAV 202
                ND+   +D +++         +SNS + + +  + D+    SS  +S  ++  +  
Sbjct: 785  ---SNDSSNSSDSSDSSNSSD----SSNSSDSSDSSDSSDSDSSNSS--DSSNSSDSSDS 835

Query: 203  SQTGFSYDENTGLYFDHSTGFYYDSENQLYYDPSTGIYYYCDVESGRYQFHSRVDLQPYP 262
            S +  S D +     D S G   DS N+     S+      D        +S        
Sbjct: 836  SNSSDSSDSS-----DSSDGSDSDSSNRSDSSNSS------DSSDSSDSSNSSDSSDSSD 884

Query: 263  TSSTKQSKDKKLKKKRKDPDSSATNEEKDLNSEDQKAFSVEHTSCNEEENFANMKKKAKI 322
            ++ +  S D        D DSS ++   D +     + S E ++ ++  N ++       
Sbjct: 885  SNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSS----- 939

Query: 323  GIHHKNSPPKVTVPTSGNTIESPLHENISNSTSFKDEKIMETDSEPEEGEITDSQTEDSY 382
                 NS        S N+ +S    + SNS+   D     +DS         S + DS 
Sbjct: 940  -----NSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSN--SSDSSDSSNSSDSSDSSDSS 992

Query: 383  DEAITSEGNVTAEDSEDED 401
            D + +S+ + +++ S+  D
Sbjct: 993  DSSDSSDSSNSSDSSDSSD 1011



 Score = 37.0 bits (84), Expect = 0.064
 Identities = 53/284 (18%), Positives = 112/284 (39%), Gaps = 23/284 (8%)

Query: 125 SDQQDQAIETSILNSKDHLQVENDAYPGTDRTENVKYRQVDHFASNSQEPASALATEDTS 184
           SD  D +  +   +S D    ++++   +D +++      D  +S+S   + +  + D+S
Sbjct: 552 SDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSS 611

Query: 185 LEGSSLAESLRAAAEAAVSQTGFSYDENTGLYFDHSTGFYYDSENQLYYDPSTGIYYYCD 244
            + S  ++S  + ++++ S++  S  ++     D S     DS +      S+      D
Sbjct: 612 -DSSDSSDSSDSKSDSSKSESDSSDSDSKS---DSSDSNSSDSSDNSDSSDSSNSSNSSD 667

Query: 245 VESGRYQFHSRVDLQPYPTSSTKQSKDKKLKKKRKDPDSSATNEEKDLNSEDQKAFSVEH 304
                    S        +S +  S D          +SS +++  D +S D    S  +
Sbjct: 668 SSDSSDSSDSSSSSDSSNSSDSSDSSDSS-----NSSESSDSSDSSDSDSSDSSDSSNSN 722

Query: 305 TSCNEEENFANMKKKAKIGIHHKNSPPKVTVPTSGNTIESPLHENISNSTSFKD--EKIM 362
           +S ++  N ++    +       NS        S N+ +S    + SNS+   D  +   
Sbjct: 723 SSDSDSSNSSDSSDSS-------NSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSD 775

Query: 363 ETDSEPEEGEITDSQTEDSYDEAITSEGNVTAE-----DSEDED 401
            +DS         S + DS D + +S+ + +++     DS D D
Sbjct: 776 SSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSD 819



 Score = 36.6 bits (83), Expect = 0.083
 Identities = 53/325 (16%), Positives = 121/325 (37%), Gaps = 7/325 (2%)

Query: 83   NEDNKKSDVEVQTENHAPWSISDYFYQTYYNDVSLPNKVTELSDQQDQAIETSILNSKDH 142
            + D+  SD    + +      SD    +  +D S  +  ++ SD  D +  +   NS D 
Sbjct: 968  SSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDS 1027

Query: 143  LQVENDAYPGTDRTENVKYRQVDHFASNSQEPASALATEDTSLEGSSLAESLRAAAEAAV 202
                +D+   +D +++         + +S    S+ +++ +    SS +     ++E++ 
Sbjct: 1028 SN-SSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSD 1086

Query: 203  SQTGFSYDENTGLYFDHSTGFYYDSENQLYYDPSTGIYYYCDVESGRYQFHSRVDLQPYP 262
            S    +  +++       +    DS +      S+      D         S        
Sbjct: 1087 SSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSD 1146

Query: 263  TSSTKQSKDKKLKKKRKDP-DSSATNEEKDLNSEDQKAFSVEHTSCNEEENFANMKKKAK 321
            +S +  S D        D  DSS +++  D ++    + S + +  ++  + ++    + 
Sbjct: 1147 SSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSD 1206

Query: 322  IGIHHKNSPPKVTVPTSGNTIESPLHENISNSTSFKDEKIMETDSEPEEGEITDSQTEDS 381
                  +S    +  +S ++  S  +E+ S+S+   D       S+  +   +   T DS
Sbjct: 1207 SSDSSDSSDSSDSSDSSDSSDSSDSNES-SDSSDSSDSSDSSNSSDSSDSSDSSDSTSDS 1265

Query: 382  YDEAITSE----GNVTAEDSEDEDE 402
             DE+ +      GN    DS+ + E
Sbjct: 1266 NDESDSQSKSGNGNNNGSDSDSDSE 1290



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 65/290 (22%), Positives = 105/290 (36%), Gaps = 42/290 (14%)

Query: 125 SDQQDQAIETSILNSKDHLQVE---NDAYPGTDRTENVKYRQVDHFASNSQEPASALATE 181
           +D +D+ IE S  N  +  ++    N    GT   E       D    NS    S    +
Sbjct: 193 TDNEDEIIENSCRNEGNTSEITPQINSKRNGTKEAEVTPGTGEDAGLDNSDGSPSGNGAD 252

Query: 182 DTSLEGSSLAESLRAAAEAAVSQTGFSYD-ENTGLYFDHSTGFYYDSENQLYYDPSTGIY 240
           +   EGS   E   A      S      + ++ G   DH +    +S+++ YYDP     
Sbjct: 253 EDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGKEDDHDSSIGQNSDSKEYYDP----- 307

Query: 241 YYCDVESGRYQFHSRVDLQPYPTSSTKQSKDKKLKKK-RKDPDSSATNEEKDLNSEDQKA 299
                  G+   H+ VD         K SK ++      +D  S    + + LN  + K 
Sbjct: 308 ------EGKEDPHNEVD-------GDKTSKSEENSAGIPEDNGSQRIEDTQKLNHRESK- 353

Query: 300 FSVEHTSCNEEENFANMKKKAKIGIHHKNSPPKVTVPTSGNTIESPLHENISNSTSFKDE 359
             VE+    E E  A  K + K GI  K        P+SGN     + + +      K++
Sbjct: 354 -RVENRITKESETHAVGKSQDK-GIEIKG-------PSSGN---RNITKEVGKGNEGKED 401

Query: 360 K-----IMETDSEPEEGEITDSQTEDSYDEAITSEGNV-TAEDSEDEDED 403
           K     I+   +   +GE+ + +      E     G+  T  DS  +  D
Sbjct: 402 KGQHGMILGKGNVKTQGEVVNIEGPGQKSEPGNKVGHSNTGSDSNSDGYD 451



 Score = 35.8 bits (81), Expect = 0.14
 Identities = 28/141 (19%), Positives = 55/141 (39%), Gaps = 5/141 (3%)

Query: 263 TSSTKQSKDKKLKKKRKDPDSSATNEEKDLNSEDQKAFSVEHTSCNEEENFANMKKKAKI 322
           +SS   S D        D DSS ++   D +     + S + +  ++ ++ ++  +    
Sbjct: 576 SSSDSDSSDSD-SSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSS 634

Query: 323 GIHHKNSPPKVTVPTSGNTIESPLHENISNSTSFKDEKIMETDSEPEEGEITDSQTEDSY 382
               K+         S +  +S    N SNS+   D     +DS         S + DS 
Sbjct: 635 DSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDS----SDSSDSSSSSDSSNSSDSS 690

Query: 383 DEAITSEGNVTAEDSEDEDED 403
           D + +S  + +++ S+  D D
Sbjct: 691 DSSDSSNSSESSDSSDSSDSD 711



 Score = 35.4 bits (80), Expect = 0.19
 Identities = 59/335 (17%), Positives = 124/335 (37%), Gaps = 16/335 (4%)

Query: 83  NEDNKKSDVEVQTENHAPWSISDYFYQTYYNDVSLPNKVTELSDQQDQAIETSILNSKDH 142
           ++ N  SD +    + +  S SD    +  +D S  +  ++ SD  D +   S  +  + 
Sbjct: 572 SDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSES 631

Query: 143 LQVENDAYP------GTDRTENVKYRQVDHFASNSQEPASALATEDTSLEGSS----LAE 192
              ++D+         +D ++N       + +++S    S+ +++ +S   SS     ++
Sbjct: 632 DSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSD 691

Query: 193 SLRAAAEAAVSQTGFSYDENTGLYFDHSTGFYYDSENQLYYDPSTGIYYYCDVESGRYQF 252
           S  ++  +  S +  S D ++    D S     DS++    D S       D        
Sbjct: 692 SSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNS-SDSSDSSDSS 750

Query: 253 HSRVDLQPYPTSSTKQSKDKKLKKKRKDPDSSATNEEKDLNSEDQKAFSVEHTSCNEEEN 312
           +S        +S++  S D        D  +S+ + +   NS D    S    S N  ++
Sbjct: 751 NSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSS-NSSDSSDSSNSSDSSNSSDS 809

Query: 313 FANMKKKAKIGIHHKNSPPKVTVPTSGNTIESPLHENISNST----SFKDEKIMETDSEP 368
             +         +  +S        S N+ +S    + S+ +    S + +    +DS  
Sbjct: 810 SDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSD 869

Query: 369 EEGEITDSQTEDSYDEAITSEGNVTAEDSEDEDED 403
                  S + DS D   +S  + +++ S   D D
Sbjct: 870 SSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSD 904



 Score = 31.2 bits (69), Expect = 3.5
 Identities = 33/187 (17%), Positives = 69/187 (36%), Gaps = 11/187 (5%)

Query: 218 DHSTGFYYDSENQLYYDPSTGIYYYCDVESGRYQFHSRVDLQPYPTSSTKQSKDKKLKKK 277
           D    + +D ++    DP++      D  +G    +S  D           + D+     
Sbjct: 448 DGYDSYDFDDKSMQGDDPNSS-----DESNGNDDANSESDNNSSSRGDASYNSDESKDNG 502

Query: 278 RKDPDSSATNEEKDLNSEDQKAFSVEHTSCNEEENFANMKKKAKIGIHHKNSPPKVTVPT 337
                  A +++ D  S+   + S  + +   ++N  +   K K      +S        
Sbjct: 503 NGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSD 562

Query: 338 SGNTIESPLHENISNSTSFKDEKIMETDSEPEEGEITDSQTEDSYDEAITSEGNVTAEDS 397
           S ++ +S   +  SNS+S  D     +DS+  +   +DS    +  ++  S  +  + DS
Sbjct: 563 SSDSSDSDSSD--SNSSSDSDS----SDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDS 616

Query: 398 EDEDEDK 404
            D  + K
Sbjct: 617 SDSSDSK 623


>gi|63003897 transcription factor NRF [Homo sapiens]
          Length = 690

 Score = 46.6 bits (109), Expect = 8e-05
 Identities = 25/66 (37%), Positives = 35/66 (53%), Gaps = 1/66 (1%)

Query: 596 EQVGSEGTFQRDDAPASVHSEITDSNKGRKMLEKMGWKKGEGLGKDGGGMKTPIQLQLRR 655
           E V S    Q   A  +   +I + N G ++L KMGW  G GLGK G G++ PI ++ + 
Sbjct: 528 EDVISRNEIQGRSAEEAYKQQIKEDNIGNQLLRKMGWTGG-GLGKSGEGIREPISVKEQH 586

Query: 656 THAGLG 661
              GLG
Sbjct: 587 KREGLG 592


>gi|4758648 kinesin family member 5B [Homo sapiens]
          Length = 963

 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 36/159 (22%), Positives = 74/159 (46%), Gaps = 15/159 (9%)

Query: 19  EPELAQLRRKVEKLERELRSCKRQVREIEKLLHHTERLYQNAESNNQELRTQVEELSKIL 78
           E    +  +K+E+ E+EL +C+ ++ + E  +       QN E   ++L   V+ LS+ L
Sbjct: 612 ESTQTESNKKMEENEKELAACQLRISQHEAKIKSLTEYLQNVEQKKRQLEESVDALSEEL 671

Query: 79  -----QRGRNEDNKKSDVEVQTENHAPWSISDYFY---QTYYNDVS-----LPNKVTELS 125
                Q   +E  K+   +VQT N    ++        +T+   +S     +  K   ++
Sbjct: 672 VQLRAQEKVHEMEKEHLNKVQTANEVKQAVEQQIQSHRETHQKQISSLRDEVEAKAKLIT 731

Query: 126 DQQDQAIETSILNSKDHLQVENDAYPGTDRTENVKYRQV 164
           D QDQ     ++  ++ L+VE++    TD+ ++ K  ++
Sbjct: 732 DLQDQ--NQKMMLEQERLRVEHEKLKATDQEKSRKLHEL 768


>gi|50658069 phosphodiesterase 4D interacting protein isoform 2
           [Homo sapiens]
          Length = 969

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 39/175 (22%), Positives = 80/175 (45%), Gaps = 16/175 (9%)

Query: 21  ELAQLRRKVEKLERELRSCKRQVREIEKLLHHTERLYQNAESNNQELRTQVEELSKILQR 80
           E+ +L+R V + ER+L   K+ V+ +E   H +E+  + +  +NQELR  +++L + LQ 
Sbjct: 354 EIQKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQKEASWKHNQELRKALQQLQEELQN 413

Query: 81  GRN-----EDNKKSDVEVQTEN--HAPWSIS--DYFYQTYYNDVSLPNKVTELSDQQDQA 131
                   E  K +++  Q +N  H   S+S  +   Q +        ++ +  D  D+ 
Sbjct: 414 KSQQLRAWEAEKYNEIRTQEQNIQHLNHSLSHKEQLLQEF-------RELLQYRDNSDKT 466

Query: 132 IETSILNSKDHLQVENDAYPGTDRTENVKYRQVDHFASNSQEPASALATEDTSLE 186
           +E + +  +   Q  +D     +R  + K+  ++      ++   A+   D  LE
Sbjct: 467 LEANEMLLEKLRQRIHDKAVALERAIDEKFSALEEKEKELRQLRLAVRERDHDLE 521


>gi|50658071 phosphodiesterase 4D interacting protein isoform 5
           [Homo sapiens]
          Length = 1132

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 39/175 (22%), Positives = 80/175 (45%), Gaps = 16/175 (9%)

Query: 21  ELAQLRRKVEKLERELRSCKRQVREIEKLLHHTERLYQNAESNNQELRTQVEELSKILQR 80
           E+ +L+R V + ER+L   K+ V+ +E   H +E+  + +  +NQELR  +++L + LQ 
Sbjct: 517 EIQKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQKEASWKHNQELRKALQQLQEELQN 576

Query: 81  GRN-----EDNKKSDVEVQTEN--HAPWSIS--DYFYQTYYNDVSLPNKVTELSDQQDQA 131
                   E  K +++  Q +N  H   S+S  +   Q +        ++ +  D  D+ 
Sbjct: 577 KSQQLRAWEAEKYNEIRTQEQNIQHLNHSLSHKEQLLQEF-------RELLQYRDNSDKT 629

Query: 132 IETSILNSKDHLQVENDAYPGTDRTENVKYRQVDHFASNSQEPASALATEDTSLE 186
           +E + +  +   Q  +D     +R  + K+  ++      ++   A+   D  LE
Sbjct: 630 LEANEMLLEKLRQRIHDKAVALERAIDEKFSALEEKEKELRQLRLAVRERDHDLE 684


>gi|157311604 phosphodiesterase 4D interacting protein isoform 1
           [Homo sapiens]
          Length = 2346

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 39/175 (22%), Positives = 80/175 (45%), Gaps = 16/175 (9%)

Query: 21  ELAQLRRKVEKLERELRSCKRQVREIEKLLHHTERLYQNAESNNQELRTQVEELSKILQR 80
           E+ +L+R V + ER+L   K+ V+ +E   H +E+  + +  +NQELR  +++L + LQ 
Sbjct: 354 EIQKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQKEASWKHNQELRKALQQLQEELQN 413

Query: 81  GRN-----EDNKKSDVEVQTEN--HAPWSIS--DYFYQTYYNDVSLPNKVTELSDQQDQA 131
                   E  K +++  Q +N  H   S+S  +   Q +        ++ +  D  D+ 
Sbjct: 414 KSQQLRAWEAEKYNEIRTQEQNIQHLNHSLSHKEQLLQEF-------RELLQYRDNSDKT 466

Query: 132 IETSILNSKDHLQVENDAYPGTDRTENVKYRQVDHFASNSQEPASALATEDTSLE 186
           +E + +  +   Q  +D     +R  + K+  ++      ++   A+   D  LE
Sbjct: 467 LEANEMLLEKLRQRIHDKAVALERAIDEKFSALEEKEKELRQLRLAVRERDHDLE 521


>gi|87299628 biorientation of chromosomes in cell division 1-like
           [Homo sapiens]
          Length = 3051

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 82/391 (20%), Positives = 148/391 (37%), Gaps = 76/391 (19%)

Query: 266 TKQSKDKKLKKKRKDPDSSATNE-EKDLNSEDQKAFSVEHTSCNEEENFANMKKKAKIGI 324
           + + K+K   K  K PDS+   E +K+   + +K F  +H+  +E+      +K+AK   
Sbjct: 311 SSEQKNKSTDKGEKKPDSNEKGERKKEKKEKTEKKF--DHSKKSEDTQKVKDEKQAK--- 365

Query: 325 HHKNSPPKVTVPTSGNTIESPLHENISNSTSFKDEKIME-TDSEPEEGEITD--SQTEDS 381
             +     + +P+  N+ ++   E      S  D  +   TD        +D  S  ED+
Sbjct: 366 --EKEVESLKLPSEKNSNKAKTVEGTKEDFSLIDSDVDGLTDITVSSVHTSDLSSFEEDT 423

Query: 382 YDEAITS----EGNVTAEDSEDEDEDKIWPPCIRVIVIRSPVLQIGSLFIITAVNPATIG 437
            +E +TS    EG +T++D E   ++K                        T  + ++ G
Sbjct: 424 EEEVVTSDSMEEGEITSDDEEKNKQNK----------------------TKTQTSDSSEG 461

Query: 438 REKDMEHTLRIPEVGVSKFHAEIYFDHDLQSYVLVDQGSQNGTIVNGKQILQPKTKCDPY 497
           + K + H         SK+++      D    + V+Q  Q  +I   K+    + + +  
Sbjct: 462 KTKSVRHAYVHKPYLYSKYYS------DSDDELTVEQRRQ--SIAKEKEERLLRRQINRE 513

Query: 498 VLEHGDEVKIGETVLSFHIHPGSDTCDGCEPGQVRAHLRLDKKDESFVGPTLS------K 551
            LE   + K  +T  S               GQ R+ + L++     + P  +      K
Sbjct: 514 KLEEKRKQKAEKTKSS------------KTKGQGRSSVDLEESSTKSLEPKAARIKEVLK 561

Query: 552 EEKELERRKELKKIRVKYG---------LQNTEYEDEKTLKN----PKYKDRAGKRREQV 598
           E K LE++  L K R K            Q  E + ++TLK      K K  + K  + V
Sbjct: 562 ERKVLEKKVALSKKRKKDSRNVEENSKKKQQYEEDSKETLKTSEHCEKEKISSSKELKHV 621

Query: 599 GSEGTFQRDDAPASVHSEITDSNKGRKMLEK 629
            ++    +     S    + D NK    LE+
Sbjct: 622 HAKSEPSKPARRLSESLHVVDENKNESKLER 652



 Score = 32.7 bits (73), Expect = 1.2
 Identities = 38/150 (25%), Positives = 64/150 (42%), Gaps = 16/150 (10%)

Query: 259 QPYPTSSTKQSKDKKLKKKRKDPDSSATNEEKDLNSEDQ-KAFSVEHTSCNEEENFANMK 317
           +P      ++ K+KK K ++K   S  + + + +  E Q K   VE      E+N     
Sbjct: 325 KPDSNEKGERKKEKKEKTEKKFDHSKKSEDTQKVKDEKQAKEKEVESLKLPSEKN----S 380

Query: 318 KKAKIGIHHKNSPPKVTVPTSGNTIESPLHENISNSTSFKD---EKIMETDSEPEEGEIT 374
            KAK     K     +     G T  +    + S+ +SF++   E+++ +DS  EEGEIT
Sbjct: 381 NKAKTVEGTKEDFSLIDSDVDGLTDITVSSVHTSDLSSFEEDTEEEVVTSDSM-EEGEIT 439

Query: 375 DSQTEDSYDEAITSEGNVTAEDSEDEDEDK 404
                   D+   ++ N T   + D  E K
Sbjct: 440 S-------DDEEKNKQNKTKTQTSDSSEGK 462



 Score = 30.0 bits (66), Expect = 7.8
 Identities = 78/400 (19%), Positives = 157/400 (39%), Gaps = 56/400 (14%)

Query: 26   RRKVEKLERELRSCKRQVREIEKLLHHTERLYQNAESNNQELRTQVEELSKILQRGRNED 85
            R+   + ER+L    +  + + + +  T+   +  E+N +E R   E+     +  R+ D
Sbjct: 789  RKSKHRNERKLSVLGKDGKPVSEYIIKTDENVRK-ENNKKERRLSAEKTKAEHKSRRSSD 847

Query: 86   NKKSDVEVQTENHA--------PWSISDYFYQTYYNDVSL-PNKVTELSDQQDQAI--ET 134
            +K     + ++ H          +S       +   D +L P +V     ++ +++  E 
Sbjct: 848  SKIQKDSLGSKQHGITLQRRSESYSEDKCDMDSTNMDSNLKPEEVVHKEKRRTKSLLEEK 907

Query: 135  SILNSKDHLQ------VENDAYPG-TDRTENVKYRQVDHFASNSQEPASALATEDTSLEG 187
             +L SK   Q      VE +   G T +    K  +  +   N  E       ED   E 
Sbjct: 908  LVLKSKSKTQGKQVKVVETELQEGATKQATTPKPDKEKNTEENDSEKQRKSKVEDKPFEE 967

Query: 188  SSLAESLRAAAEAAVSQTGFSYDENTGLYFDHSTGFYYDSENQLYYDPSTGIYYYCDVES 247
            + +   L  A+ +A                 HST    DS ++    P     Y  D +S
Sbjct: 968  TGVEPVLETASSSA-----------------HST--QKDSSHRAKL-PLAKEKYKSDKDS 1007

Query: 248  GRYQFHSRVDLQPYPTSSTKQSKDKKLKKKRKDPDSSATNEEKDLNSEDQKAFSVEHTSC 307
               +   ++       S    SKD K    +KD + S   + K+++S  +KA    ++S 
Sbjct: 1008 TSTRLERKLSDGHKSRSLKHSSKDIK----KKDENKSDDKDGKEVDSSHEKARG--NSSL 1061

Query: 308  NEEENFANM--KKKAKIGIHHKNSPPKVTVPT----SGNTIESPLHENISNSTSFKDEKI 361
             E++    +   ++  +         K+   T    SG++++ P  +   + T   +++ 
Sbjct: 1062 MEKKLSRRLCENRRGSLSQEMAKGEEKLAANTLSTPSGSSLQRP--KKSGDMTLIPEQEP 1119

Query: 362  METDSEP-EEGEITDSQTEDSYDEAITSEGNVTAEDSEDE 400
            ME DSEP  E     S+T+D+ +    S+ ++ +E+ + +
Sbjct: 1120 MEIDSEPGVENVFEVSKTQDNRNN--NSQQDIDSENMKQK 1157


>gi|50962882 G patch domain containing 8 [Homo sapiens]
          Length = 1502

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 20/51 (39%), Positives = 29/51 (56%)

Query: 611 ASVHSEITDSNKGRKMLEKMGWKKGEGLGKDGGGMKTPIQLQLRRTHAGLG 661
           AS+   I   N G ++L+K GWK G+GLGK   G   PI + ++    G+G
Sbjct: 32  ASLDKPIESDNIGHRLLQKHGWKLGQGLGKSLQGRTDPIPIVVKYDVMGMG 82


>gi|38045919 huntingtin interacting protein 1 [Homo sapiens]
          Length = 1037

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 41/187 (21%), Positives = 80/187 (42%), Gaps = 5/187 (2%)

Query: 23  AQLRRKVEKLERELRSCKRQVREIEKLLHHTERLYQNAESNNQELRTQVEELSKILQRGR 82
           AQL     + +R +   K  V E+E  L   + L Q A  + + LR +++EL +  +   
Sbjct: 389 AQLENMKTESQRVVLQLKGHVSELEADLAEQQHLRQQAADDCEFLRAELDELRRQREDTE 448

Query: 83  NEDNKKSDVE--VQTENHAPWSISDYFYQTYYNDVSLPNKVTELSDQQDQAIETSILNSK 140
                 S++E   Q        + + + +   N   L  K  E++ Q   A +  +   +
Sbjct: 449 KAQRSLSEIERKAQANEQRYSKLKEKYSELVQNHADLLRKNAEVTKQVSMARQAQVDLER 508

Query: 141 DHLQVENDAYPGTDRTENVKYRQVDHFASNSQEPASA---LATEDTSLEGSSLAESLRAA 197
           +  ++E+     +D+ +     Q++   S  QE A++   L     SLE S+ +E+  AA
Sbjct: 509 EKKELEDSLERISDQGQRKTQEQLEVLESLKQELATSQRELQVLQGSLETSAQSEANWAA 568

Query: 198 AEAAVSQ 204
             A + +
Sbjct: 569 EFAELEK 575


>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
          Length = 2230

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 42/169 (24%), Positives = 73/169 (43%), Gaps = 32/169 (18%)

Query: 19  EPELAQLRRKVEKLERELRSCKRQVREIE--------KLLHH---TERLYQNAESNNQEL 67
           E +LAQL++K+  LE E     +QV E+E        +L  H    + L Q  E  N E+
Sbjct: 818 EEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEM 877

Query: 68  RTQVEELSKILQRGRNEDNKKSDVEVQTENHAPWSISDYFYQTYYNDVSLPNKVTELSDQ 127
             +V+ L+++ +    + NK+ +                  QT    V   N + ++ + 
Sbjct: 878 EQKVKSLTQVYESKLEDGNKEQE------------------QTKQILVEKENMILQMREG 919

Query: 128 QDQAIE--TSILNSK-DHLQVENDAYPGTDRTENVKYRQVDHFASNSQE 173
           Q + IE  T  L++K D + + N+ Y    + +  K  +V   A   QE
Sbjct: 920 QKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQE 968


>gi|119226260 calcium homeostasis endoplasmic reticulum protein
           [Homo sapiens]
          Length = 916

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 29/121 (23%), Positives = 48/121 (39%), Gaps = 2/121 (1%)

Query: 532 RAHLRLDKKDESFVGPTLSKEEKELERRKELKKIRVKYGLQNTEYEDEKTLKN--PKYKD 589
           R++ R  K   S+         +   R +   + R +     +  +     K+  P  + 
Sbjct: 752 RSNSRSSKSSGSYSRSRSRSCSRSYSRSRSRSRSRSRSSRSRSRSQSRSRSKSYSPGRRR 811

Query: 590 RAGKRREQVGSEGTFQRDDAPASVHSEITDSNKGRKMLEKMGWKKGEGLGKDGGGMKTPI 649
           R+  R     S      + AP    S + + NKG +ML KMGW    GLG    G++ PI
Sbjct: 812 RSRSRSPTPPSSAGLGSNSAPPIPDSRLGEENKGHQMLVKMGWSGSGGLGAKEQGIQDPI 871

Query: 650 Q 650
           +
Sbjct: 872 K 872


>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
          Length = 770

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 37/159 (23%), Positives = 70/159 (44%), Gaps = 25/159 (15%)

Query: 253 HSRVDLQPYPTSSTKQSKDKKL----KKKRKDPDSSATNEEKDLNSEDQKAFSVEHTSCN 308
           HSR +         K+ +++K+    K++R+  +     EE+    E ++  S  H +  
Sbjct: 148 HSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMR 207

Query: 309 EEENFANMKKKAKIGIHHKNSPPKVTVPTSGNTIESPLHENIS---NSTSFKDEKIMETD 365
           E+ +    K KA    H   SPP+            P  E           K+EK+ E D
Sbjct: 208 EDYSD---KVKAS---HWSRSPPR------------PPRERFELGDGRKPVKEEKMEERD 249

Query: 366 SEPEEGEITDSQTEDSYDEAITSEGNVTAEDSEDEDEDK 404
              +  +I+DS+ + S  E+ ++E    +E+ E+E+E++
Sbjct: 250 LLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEE 288



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 33/131 (25%), Positives = 61/131 (46%), Gaps = 9/131 (6%)

Query: 10  RSPPPPTSPEPELAQLRR--KVEKL-ERELRSCKRQVREIEKLLHHTERLYQNAESNNQE 66
           RSPP P     EL   R+  K EK+ ER+L S  + + + E+     E    +AES +  
Sbjct: 221 RSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAES--SSAESGSGS 278

Query: 67  LRTQVEELSKILQRGRNEDNKKSDVEVQTENHAPWSISDYFYQTYYNDVSLPNKVTELSD 126
              + EE  +  +   +E++++ + E + E     S S+   +    +VS      E+S+
Sbjct: 279 EEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVS----EEEMSE 334

Query: 127 QQDQAIETSIL 137
            +++  E  +L
Sbjct: 335 DEERENENHLL 345


>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
          Length = 780

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 37/159 (23%), Positives = 70/159 (44%), Gaps = 25/159 (15%)

Query: 253 HSRVDLQPYPTSSTKQSKDKKL----KKKRKDPDSSATNEEKDLNSEDQKAFSVEHTSCN 308
           HSR +         K+ +++K+    K++R+  +     EE+    E ++  S  H +  
Sbjct: 158 HSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMR 217

Query: 309 EEENFANMKKKAKIGIHHKNSPPKVTVPTSGNTIESPLHENIS---NSTSFKDEKIMETD 365
           E+ +    K KA    H   SPP+            P  E           K+EK+ E D
Sbjct: 218 EDYSD---KVKAS---HWSRSPPR------------PPRERFELGDGRKPVKEEKMEERD 259

Query: 366 SEPEEGEITDSQTEDSYDEAITSEGNVTAEDSEDEDEDK 404
              +  +I+DS+ + S  E+ ++E    +E+ E+E+E++
Sbjct: 260 LLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEE 298



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 33/131 (25%), Positives = 61/131 (46%), Gaps = 9/131 (6%)

Query: 10  RSPPPPTSPEPELAQLRR--KVEKL-ERELRSCKRQVREIEKLLHHTERLYQNAESNNQE 66
           RSPP P     EL   R+  K EK+ ER+L S  + + + E+     E    +AES +  
Sbjct: 231 RSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAES--SSAESGSGS 288

Query: 67  LRTQVEELSKILQRGRNEDNKKSDVEVQTENHAPWSISDYFYQTYYNDVSLPNKVTELSD 126
              + EE  +  +   +E++++ + E + E     S S+   +    +VS      E+S+
Sbjct: 289 EEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVS----EEEMSE 344

Query: 127 QQDQAIETSIL 137
            +++  E  +L
Sbjct: 345 DEERENENHLL 355


>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           9 [Homo sapiens]
          Length = 771

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 37/159 (23%), Positives = 70/159 (44%), Gaps = 25/159 (15%)

Query: 253 HSRVDLQPYPTSSTKQSKDKKL----KKKRKDPDSSATNEEKDLNSEDQKAFSVEHTSCN 308
           HSR +         K+ +++K+    K++R+  +     EE+    E ++  S  H +  
Sbjct: 149 HSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMR 208

Query: 309 EEENFANMKKKAKIGIHHKNSPPKVTVPTSGNTIESPLHENIS---NSTSFKDEKIMETD 365
           E+ +    K KA    H   SPP+            P  E           K+EK+ E D
Sbjct: 209 EDYSD---KVKAS---HWSRSPPR------------PPRERFELGDGRKPVKEEKMEERD 250

Query: 366 SEPEEGEITDSQTEDSYDEAITSEGNVTAEDSEDEDEDK 404
              +  +I+DS+ + S  E+ ++E    +E+ E+E+E++
Sbjct: 251 LLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEE 289



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 33/131 (25%), Positives = 61/131 (46%), Gaps = 9/131 (6%)

Query: 10  RSPPPPTSPEPELAQLRR--KVEKL-ERELRSCKRQVREIEKLLHHTERLYQNAESNNQE 66
           RSPP P     EL   R+  K EK+ ER+L S  + + + E+     E    +AES +  
Sbjct: 222 RSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAES--SSAESGSGS 279

Query: 67  LRTQVEELSKILQRGRNEDNKKSDVEVQTENHAPWSISDYFYQTYYNDVSLPNKVTELSD 126
              + EE  +  +   +E++++ + E + E     S S+   +    +VS      E+S+
Sbjct: 280 EEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVS----EEEMSE 335

Query: 127 QQDQAIETSIL 137
            +++  E  +L
Sbjct: 336 DEERENENHLL 346


>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           5 [Homo sapiens]
          Length = 748

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 37/159 (23%), Positives = 70/159 (44%), Gaps = 25/159 (15%)

Query: 253 HSRVDLQPYPTSSTKQSKDKKL----KKKRKDPDSSATNEEKDLNSEDQKAFSVEHTSCN 308
           HSR +         K+ +++K+    K++R+  +     EE+    E ++  S  H +  
Sbjct: 126 HSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMR 185

Query: 309 EEENFANMKKKAKIGIHHKNSPPKVTVPTSGNTIESPLHENIS---NSTSFKDEKIMETD 365
           E+ +    K KA    H   SPP+            P  E           K+EK+ E D
Sbjct: 186 EDYSD---KVKAS---HWSRSPPR------------PPRERFELGDGRKPVKEEKMEERD 227

Query: 366 SEPEEGEITDSQTEDSYDEAITSEGNVTAEDSEDEDEDK 404
              +  +I+DS+ + S  E+ ++E    +E+ E+E+E++
Sbjct: 228 LLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEE 266



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 33/131 (25%), Positives = 61/131 (46%), Gaps = 9/131 (6%)

Query: 10  RSPPPPTSPEPELAQLRR--KVEKL-ERELRSCKRQVREIEKLLHHTERLYQNAESNNQE 66
           RSPP P     EL   R+  K EK+ ER+L S  + + + E+     E    +AES +  
Sbjct: 199 RSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAES--SSAESGSGS 256

Query: 67  LRTQVEELSKILQRGRNEDNKKSDVEVQTENHAPWSISDYFYQTYYNDVSLPNKVTELSD 126
              + EE  +  +   +E++++ + E + E     S S+   +    +VS      E+S+
Sbjct: 257 EEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVS----EEEMSE 312

Query: 127 QQDQAIETSIL 137
            +++  E  +L
Sbjct: 313 DEERENENHLL 323


>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           4 [Homo sapiens]
          Length = 737

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 37/159 (23%), Positives = 70/159 (44%), Gaps = 25/159 (15%)

Query: 253 HSRVDLQPYPTSSTKQSKDKKL----KKKRKDPDSSATNEEKDLNSEDQKAFSVEHTSCN 308
           HSR +         K+ +++K+    K++R+  +     EE+    E ++  S  H +  
Sbjct: 115 HSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMR 174

Query: 309 EEENFANMKKKAKIGIHHKNSPPKVTVPTSGNTIESPLHENIS---NSTSFKDEKIMETD 365
           E+ +    K KA    H   SPP+            P  E           K+EK+ E D
Sbjct: 175 EDYSD---KVKAS---HWSRSPPR------------PPRERFELGDGRKPVKEEKMEERD 216

Query: 366 SEPEEGEITDSQTEDSYDEAITSEGNVTAEDSEDEDEDK 404
              +  +I+DS+ + S  E+ ++E    +E+ E+E+E++
Sbjct: 217 LLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEE 255



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 33/131 (25%), Positives = 61/131 (46%), Gaps = 9/131 (6%)

Query: 10  RSPPPPTSPEPELAQLRR--KVEKL-ERELRSCKRQVREIEKLLHHTERLYQNAESNNQE 66
           RSPP P     EL   R+  K EK+ ER+L S  + + + E+     E    +AES +  
Sbjct: 188 RSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAES--SSAESGSGS 245

Query: 67  LRTQVEELSKILQRGRNEDNKKSDVEVQTENHAPWSISDYFYQTYYNDVSLPNKVTELSD 126
              + EE  +  +   +E++++ + E + E     S S+   +    +VS      E+S+
Sbjct: 246 EEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVS----EEEMSE 301

Query: 127 QQDQAIETSIL 137
            +++  E  +L
Sbjct: 302 DEERENENHLL 312


>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           2 [Homo sapiens]
          Length = 782

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 37/159 (23%), Positives = 70/159 (44%), Gaps = 25/159 (15%)

Query: 253 HSRVDLQPYPTSSTKQSKDKKL----KKKRKDPDSSATNEEKDLNSEDQKAFSVEHTSCN 308
           HSR +         K+ +++K+    K++R+  +     EE+    E ++  S  H +  
Sbjct: 160 HSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMR 219

Query: 309 EEENFANMKKKAKIGIHHKNSPPKVTVPTSGNTIESPLHENIS---NSTSFKDEKIMETD 365
           E+ +    K KA    H   SPP+            P  E           K+EK+ E D
Sbjct: 220 EDYSD---KVKAS---HWSRSPPR------------PPRERFELGDGRKPVKEEKMEERD 261

Query: 366 SEPEEGEITDSQTEDSYDEAITSEGNVTAEDSEDEDEDK 404
              +  +I+DS+ + S  E+ ++E    +E+ E+E+E++
Sbjct: 262 LLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEE 300



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 33/131 (25%), Positives = 61/131 (46%), Gaps = 9/131 (6%)

Query: 10  RSPPPPTSPEPELAQLRR--KVEKL-ERELRSCKRQVREIEKLLHHTERLYQNAESNNQE 66
           RSPP P     EL   R+  K EK+ ER+L S  + + + E+     E    +AES +  
Sbjct: 233 RSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAES--SSAESGSGS 290

Query: 67  LRTQVEELSKILQRGRNEDNKKSDVEVQTENHAPWSISDYFYQTYYNDVSLPNKVTELSD 126
              + EE  +  +   +E++++ + E + E     S S+   +    +VS      E+S+
Sbjct: 291 EEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVS----EEEMSE 346

Query: 127 QQDQAIETSIL 137
            +++  E  +L
Sbjct: 347 DEERENENHLL 357


>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
          Length = 2426

 Score = 40.4 bits (93), Expect = 0.006
 Identities = 17/38 (44%), Positives = 24/38 (63%)

Query: 623  GRKMLEKMGWKKGEGLGKDGGGMKTPIQLQLRRTHAGL 660
            G  ++ KMGW++GEGLGK+  G K PI +  +    GL
Sbjct: 2309 GAVLMRKMGWREGEGLGKNKEGNKEPILVDFKTDRKGL 2346


>gi|58535453 CDK5 regulatory subunit associated protein 2 isoform b
           [Homo sapiens]
          Length = 1814

 Score = 40.0 bits (92), Expect = 0.008
 Identities = 32/127 (25%), Positives = 62/127 (48%), Gaps = 13/127 (10%)

Query: 24  QLRRKVEKLERELRSCKRQVREIEKLLHHTERLYQNAESNNQELRTQVEELSKILQRGRN 83
           +LRR ++K+ +EL   +++   +EK L    R     +   ++LR +VE+L       RN
Sbjct: 396 RLRRSIKKITQELSDLQQERERLEKDLEEAHREKSKGDCTIRDLRNEVEKL-------RN 448

Query: 84  EDNKKSDVEVQTENHAPWSISDYFYQTYYNDVSLPNKVTELSDQQDQAIETSILNSKDHL 143
           E N++   E   EN     +S+   +  +N   +   +TE ++Q+D  ++    N KD  
Sbjct: 449 EVNER---EKAMENRYKSLLSE-SNKKLHNQEQVIKHLTESTNQKDVLLQK--FNEKDLE 502

Query: 144 QVENDAY 150
            ++ + Y
Sbjct: 503 VIQQNCY 509


>gi|58535451 CDK5 regulatory subunit associated protein 2 isoform a
           [Homo sapiens]
          Length = 1893

 Score = 40.0 bits (92), Expect = 0.008
 Identities = 32/127 (25%), Positives = 62/127 (48%), Gaps = 13/127 (10%)

Query: 24  QLRRKVEKLERELRSCKRQVREIEKLLHHTERLYQNAESNNQELRTQVEELSKILQRGRN 83
           +LRR ++K+ +EL   +++   +EK L    R     +   ++LR +VE+L       RN
Sbjct: 396 RLRRSIKKITQELSDLQQERERLEKDLEEAHREKSKGDCTIRDLRNEVEKL-------RN 448

Query: 84  EDNKKSDVEVQTENHAPWSISDYFYQTYYNDVSLPNKVTELSDQQDQAIETSILNSKDHL 143
           E N++   E   EN     +S+   +  +N   +   +TE ++Q+D  ++    N KD  
Sbjct: 449 EVNER---EKAMENRYKSLLSE-SNKKLHNQEQVIKHLTESTNQKDVLLQK--FNEKDLE 502

Query: 144 QVENDAY 150
            ++ + Y
Sbjct: 503 VIQQNCY 509


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.308    0.128    0.364 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,799,503
Number of Sequences: 37866
Number of extensions: 1559052
Number of successful extensions: 15370
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 183
Number of HSP's successfully gapped in prelim test: 454
Number of HSP's that attempted gapping in prelim test: 12727
Number of HSP's gapped (non-prelim): 2949
length of query: 714
length of database: 18,247,518
effective HSP length: 109
effective length of query: 605
effective length of database: 14,120,124
effective search space: 8542675020
effective search space used: 8542675020
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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