Guide to the Human Genome
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Search of human proteins with 124487387

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|124487387 ring finger protein 207 [Homo sapiens]
         (634 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|124487387 ring finger protein 207 [Homo sapiens]                  1287   0.0  
gi|16519559 tripartite motif protein 9 isoform 2 [Homo sapiens]        81   3e-15
gi|190341104 tripartite motif protein 9 isoform 1 [Homo sapiens]       81   3e-15
gi|30794216 tripartite motif-containing 56 [Homo sapiens]              75   2e-13
gi|194248081 tripartite motif-containing 2 isoform 2 [Homo sapiens]    69   1e-11
gi|194248079 tripartite motif-containing 2 isoform 1 [Homo sapiens]    69   1e-11
gi|67089160 promyelocytic leukemia protein isoform 11 [Homo sapi...    65   2e-10
gi|67089157 promyelocytic leukemia protein isoform 2 [Homo sapiens]    65   2e-10
gi|15451765 promyelocytic leukemia protein isoform 9 [Homo sapiens]    65   2e-10
gi|67089154 promyelocytic leukemia protein isoform 8 [Homo sapiens]    65   2e-10
gi|4505903 promyelocytic leukemia protein isoform 6 [Homo sapiens]     65   2e-10
gi|15451775 promyelocytic leukemia protein isoform 7 [Homo sapiens]    65   2e-10
gi|15451779 promyelocytic leukemia protein isoform 10 [Homo sapi...    65   2e-10
gi|67089149 promyelocytic leukemia protein isoform 1 [Homo sapiens]    65   2e-10
gi|109637788 promyelocytic leukemia protein isoform 5 [Homo sapi...    65   2e-10
gi|32454739 tripartite motif-containing 3 [Homo sapiens]               65   2e-10
gi|32454737 tripartite motif-containing 3 [Homo sapiens]               65   2e-10
gi|5032179 tripartite motif-containing 28 protein [Homo sapiens]       64   3e-10
gi|224548923 tripartite motif-containing 45 isoform 2 [Homo sapi...    59   1e-08
gi|224548921 tripartite motif-containing 45 isoform 1 [Homo sapi...    59   1e-08
gi|78482627 ring finger protein 30 isoform 1 [Homo sapiens]            57   7e-08
gi|74027251 tripartite motif-containing 33 protein isoform beta ...    54   3e-07
gi|74027249 tripartite motif-containing 33 protein isoform alpha...    54   3e-07
gi|15208643 ADP-ribosylation factor domain protein 1 isoform gam...    54   6e-07
gi|15208641 ADP-ribosylation factor domain protein 1 isoform bet...    54   6e-07
gi|4502197 ADP-ribosylation factor domain protein 1 isoform alph...    54   6e-07
gi|21630277 tripartite motif-containing 11 [Homo sapiens]              53   7e-07
gi|134288906 tripartite motif-containing 67 [Homo sapiens]             52   1e-06
gi|15208660 tripartite motif protein 21 [Homo sapiens]                 52   2e-06
gi|149193331 tripartite motif protein 15 [Homo sapiens]                52   2e-06

>gi|124487387 ring finger protein 207 [Homo sapiens]
          Length = 634

 Score = 1287 bits (3331), Expect = 0.0
 Identities = 634/634 (100%), Positives = 634/634 (100%)

Query: 1   MSGAIFGPLEGPSSLDAPSIHPLVCPLCHVQYERPCLLDCFHDFCAGCLRGRATDGRLTC 60
           MSGAIFGPLEGPSSLDAPSIHPLVCPLCHVQYERPCLLDCFHDFCAGCLRGRATDGRLTC
Sbjct: 1   MSGAIFGPLEGPSSLDAPSIHPLVCPLCHVQYERPCLLDCFHDFCAGCLRGRATDGRLTC 60

Query: 61  PLCQHQTVLKGPSGLPPVDRLLQFLVDSSGDGVEAVRCANCDLECSEQDVETTYFCNTCG 120
           PLCQHQTVLKGPSGLPPVDRLLQFLVDSSGDGVEAVRCANCDLECSEQDVETTYFCNTCG
Sbjct: 61  PLCQHQTVLKGPSGLPPVDRLLQFLVDSSGDGVEAVRCANCDLECSEQDVETTYFCNTCG 120

Query: 121 QPLCARCRDETHRARMFARHDIVALGQRSRDVPQKCTLHAEPYLLFSTDKKLLLCIRCFR 180
           QPLCARCRDETHRARMFARHDIVALGQRSRDVPQKCTLHAEPYLLFSTDKKLLLCIRCFR
Sbjct: 121 QPLCARCRDETHRARMFARHDIVALGQRSRDVPQKCTLHAEPYLLFSTDKKLLLCIRCFR 180

Query: 181 DMQKESRAHCVDLESAYVQGCERLEQAVLAVKALQTATREAIALLQAMVEEVRHSAAEEE 240
           DMQKESRAHCVDLESAYVQGCERLEQAVLAVKALQTATREAIALLQAMVEEVRHSAAEEE
Sbjct: 181 DMQKESRAHCVDLESAYVQGCERLEQAVLAVKALQTATREAIALLQAMVEEVRHSAAEEE 240

Query: 241 DAIHALFGSMQDRLAERKALLLQAVQSQYEEKDKAFKEQLSHLATLLPTLQVHLVICSSF 300
           DAIHALFGSMQDRLAERKALLLQAVQSQYEEKDKAFKEQLSHLATLLPTLQVHLVICSSF
Sbjct: 241 DAIHALFGSMQDRLAERKALLLQAVQSQYEEKDKAFKEQLSHLATLLPTLQVHLVICSSF 300

Query: 301 LSLANKAEFLDLGYELMERLQGIVTRPHHLRPIQSSKIASDHRAEFARCLEPLLLLGPRR 360
           LSLANKAEFLDLGYELMERLQGIVTRPHHLRPIQSSKIASDHRAEFARCLEPLLLLGPRR
Sbjct: 301 LSLANKAEFLDLGYELMERLQGIVTRPHHLRPIQSSKIASDHRAEFARCLEPLLLLGPRR 360

Query: 361 VAAAASGANTLAGGLGPKALTGPHCPSPVGKMSGSPVQKPTLHRSISTKVLLAEGENTPF 420
           VAAAASGANTLAGGLGPKALTGPHCPSPVGKMSGSPVQKPTLHRSISTKVLLAEGENTPF
Sbjct: 361 VAAAASGANTLAGGLGPKALTGPHCPSPVGKMSGSPVQKPTLHRSISTKVLLAEGENTPF 420

Query: 421 AEHCRHYEDSYRHLQAEMQSLKDQVQELHRDLTKHHSLIKAEIMGDVLHKSLQLDVQIAS 480
           AEHCRHYEDSYRHLQAEMQSLKDQVQELHRDLTKHHSLIKAEIMGDVLHKSLQLDVQIAS
Sbjct: 421 AEHCRHYEDSYRHLQAEMQSLKDQVQELHRDLTKHHSLIKAEIMGDVLHKSLQLDVQIAS 480

Query: 481 EHASLEGMRVVFQEIWEEAYQRVANEQEIYEAQLHDLLQLRQENAYLTTITKQITPYVRS 540
           EHASLEGMRVVFQEIWEEAYQRVANEQEIYEAQLHDLLQLRQENAYLTTITKQITPYVRS
Sbjct: 481 EHASLEGMRVVFQEIWEEAYQRVANEQEIYEAQLHDLLQLRQENAYLTTITKQITPYVRS 540

Query: 541 IAKVKERLEPRFQAPVDEQSESLQNTHDDSRNNAASARNNPGSVPEKREKTSEPKGNSWA 600
           IAKVKERLEPRFQAPVDEQSESLQNTHDDSRNNAASARNNPGSVPEKREKTSEPKGNSWA
Sbjct: 541 IAKVKERLEPRFQAPVDEQSESLQNTHDDSRNNAASARNNPGSVPEKREKTSEPKGNSWA 600

Query: 601 PNGLSEEPLLKNMDHHRSKQKNGGDVPTWREHPT 634
           PNGLSEEPLLKNMDHHRSKQKNGGDVPTWREHPT
Sbjct: 601 PNGLSEEPLLKNMDHHRSKQKNGGDVPTWREHPT 634


>gi|16519559 tripartite motif protein 9 isoform 2 [Homo sapiens]
          Length = 550

 Score = 80.9 bits (198), Expect = 3e-15
 Identities = 73/273 (26%), Positives = 123/273 (45%), Gaps = 15/273 (5%)

Query: 58  LTCPLCQHQTVL--KGPSGLPPVDRLLQFLVDSSGDGVEAVRCANCDLECSEQDVETTYF 115
           +TCP C    +L  +G  G P  +R+L+ ++D       A     C L C +   E T  
Sbjct: 126 ITCPQCHRSLILDDRGLRGFPK-NRVLEGVIDRYQQSKAAA--LKCQL-CEKAPKEATVM 181

Query: 116 CNTCGQPLCARCRDETHRAR-MFARHDIV--ALGQRSRDV-PQK---CTLHA-EPYLLFS 167
           C  C    C  CR   H  R   A+H +V  A G+ SR + P+K   CT H  E + ++ 
Sbjct: 182 CEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSPRKVSTCTDHELENHSMYC 241

Query: 168 TDKKLLLCIRCFRDMQKESRAHCVDLESAYVQGCERLEQAVLAVKALQTATREAIALLQA 227
              K+ +C +C  +  K S      L + +     +L QA+  +       +E +  L+ 
Sbjct: 242 VQCKMPVCYQCLEE-GKHSSHEVKALGAMWKLHKSQLSQALNGLSDRAKEAKEFLVQLRN 300

Query: 228 MVEEVRHSAAEEEDAIHALFGSMQDRLAERKALLLQAVQSQYEEKDKAFKEQLSHLATLL 287
           MV++++ ++ E E  + A   ++ D L  RKA LL  V  ++E K K  ++Q+SH    L
Sbjct: 301 MVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKVVRDQISHCTVKL 360

Query: 288 PTLQVHLVICSSFLSLANKAEFLDLGYELMERL 320
                 +  C   +   + + FL +   L+ R+
Sbjct: 361 RQTTGLMEYCLEVIKENDPSGFLQISDALIRRV 393



 Score = 33.9 bits (76), Expect = 0.47
 Identities = 12/28 (42%), Positives = 15/28 (53%)

Query: 23 LVCPLCHVQYERPCLLDCFHDFCAGCLR 50
          L CP+C   Y  P +L C H+ C  C R
Sbjct: 8  LKCPVCGSFYREPIILPCSHNLCQACAR 35


>gi|190341104 tripartite motif protein 9 isoform 1 [Homo sapiens]
          Length = 710

 Score = 80.9 bits (198), Expect = 3e-15
 Identities = 73/273 (26%), Positives = 123/273 (45%), Gaps = 15/273 (5%)

Query: 58  LTCPLCQHQTVL--KGPSGLPPVDRLLQFLVDSSGDGVEAVRCANCDLECSEQDVETTYF 115
           +TCP C    +L  +G  G P  +R+L+ ++D       A     C L C +   E T  
Sbjct: 126 ITCPQCHRSLILDDRGLRGFPK-NRVLEGVIDRYQQSKAAA--LKCQL-CEKAPKEATVM 181

Query: 116 CNTCGQPLCARCRDETHRAR-MFARHDIV--ALGQRSRDV-PQK---CTLHA-EPYLLFS 167
           C  C    C  CR   H  R   A+H +V  A G+ SR + P+K   CT H  E + ++ 
Sbjct: 182 CEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSPRKVSTCTDHELENHSMYC 241

Query: 168 TDKKLLLCIRCFRDMQKESRAHCVDLESAYVQGCERLEQAVLAVKALQTATREAIALLQA 227
              K+ +C +C  +  K S      L + +     +L QA+  +       +E +  L+ 
Sbjct: 242 VQCKMPVCYQCLEE-GKHSSHEVKALGAMWKLHKSQLSQALNGLSDRAKEAKEFLVQLRN 300

Query: 228 MVEEVRHSAAEEEDAIHALFGSMQDRLAERKALLLQAVQSQYEEKDKAFKEQLSHLATLL 287
           MV++++ ++ E E  + A   ++ D L  RKA LL  V  ++E K K  ++Q+SH    L
Sbjct: 301 MVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKVVRDQISHCTVKL 360

Query: 288 PTLQVHLVICSSFLSLANKAEFLDLGYELMERL 320
                 +  C   +   + + FL +   L+ R+
Sbjct: 361 RQTTGLMEYCLEVIKENDPSGFLQISDALIRRV 393



 Score = 33.9 bits (76), Expect = 0.47
 Identities = 12/28 (42%), Positives = 15/28 (53%)

Query: 23 LVCPLCHVQYERPCLLDCFHDFCAGCLR 50
          L CP+C   Y  P +L C H+ C  C R
Sbjct: 8  LKCPVCGSFYREPIILPCSHNLCQACAR 35


>gi|30794216 tripartite motif-containing 56 [Homo sapiens]
          Length = 755

 Score = 74.7 bits (182), Expect = 2e-13
 Identities = 90/337 (26%), Positives = 137/337 (40%), Gaps = 38/337 (11%)

Query: 12  PSSLDAPSIHPLVCPLCHVQYERPCLLDCFHDFCAGCLRGRATDGRLTCPLCQHQTVLKG 71
           PS L+A S   L C +C  Q   P  L C H +C  CL   A  GR+ CP C+ +TV   
Sbjct: 8   PSLLEALSSDFLACKICLEQLRAPKTLPCLHTYCQDCLAQLADGGRVRCPECR-ETVPVP 66

Query: 72  PSGLPP------VDRLLQFLVDSSGDGVEAVR--CANCDL-ECSEQDVETTYFCNTCGQP 122
           P G+        V+ LL  +   +   + A +  CA C L   +      T  C  C   
Sbjct: 67  PEGVASFKTNFFVNGLLDLVKARACGDLRAGKPACALCPLVGGTSTGGPATARCLDCADD 126

Query: 123 LCARCRDETHRARMFARHDIVAL----------GQRSRDVPQKCTLHAEPYLLFSTDK-K 171
           LC  C D     R    H +V L            R R   Q C  H    L F      
Sbjct: 127 LCQACADGHRCTRQTHTHRVVDLVGYRAGWYDEEARERQAAQ-CPQHPGEALRFLCQPCS 185

Query: 172 LLLCIRCFRDMQKESRAHCVDLESAY---VQGCERL----EQAVLAVKALQTATREAIAL 224
            LLC  C  D   +    C+ L  A      G E L    +  ++ ++A +   +EA+A 
Sbjct: 186 QLLCRECRLDPHLDH--PCLPLAEAVRARRPGLEGLLAGVDNNLVELEAARRVEKEALAR 243

Query: 225 LQAMVEEVRHSAAEEEDAIHALFGSMQDRLAERKALLLQAVQSQYEEKDKAFKEQLSHLA 284
           L+   E+      + E+A     G ++  LA+++ +L Q +++  E  ++A +E+L+ L 
Sbjct: 244 LR---EQAARVGTQVEEAAE---GVLRALLAQKQEVLGQ-LRAHVEAAEEAARERLAELE 296

Query: 285 TLLPTLQVHLVICSSFLSLANKAEFLDLGYELMERLQ 321
                 +         LSL  +AE L L   + +RL+
Sbjct: 297 GREQVARAAAAFARRVLSLGREAEILSLEGAIAQRLR 333


>gi|194248081 tripartite motif-containing 2 isoform 2 [Homo sapiens]
          Length = 744

 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 74/336 (22%), Positives = 129/336 (38%), Gaps = 77/336 (22%)

Query: 23  LVCPLCHVQYERPCLLDCFHDFCAGCLRG--RATDGRLTCPLCQHQTVL--KGPSGLPP- 77
           L+C +C  +Y+ P +L C H FC  CL+    A    L+CP+C+  ++L  KG + L   
Sbjct: 21  LICSICLERYKNPKVLPCLHTFCERCLQNYIPAHSLTLSCPVCRQTSILPEKGVAALQNN 80

Query: 78  --VDRLLQFLVDSSGDGVE--------AVRCANCDLECSEQDVET-TYFCNTCGQPLCAR 126
             +  L+  L  + G   E            A   L C   D     ++C +C   +C  
Sbjct: 81  FFITNLMDVLQRTPGSNAEESSILETVTAVAAGKPLSCPNHDGNVMEFYCQSCETAMCRE 140

Query: 127 CRDETHRARMFARHDIVALGQRSRDVPQKCTLHAEPYLLFSTDKKLLLCIRCFRDMQKES 186
           C +  H     A H  V L                                  +D+ ++ 
Sbjct: 141 CTEGEH-----AEHPTVPL----------------------------------KDVVEQH 161

Query: 187 RAHCVDLESAYVQGCERLEQAVLAVKALQTATREAIALLQAMVEEVRHSAAEEEDAIHAL 246
           +A               L+  + AV         A+  +  ++ ++ +  A   D IH+ 
Sbjct: 162 KA--------------SLQVQLDAVNKRLPEIDSALQFISEIIHQLTNQKASIVDDIHST 207

Query: 247 FGSMQDRLAERKALLLQAVQSQYEEKDKAFKEQLSHLATLLPTLQVHLVICSSF----LS 302
           F  +Q  L  RK++LL  ++  Y  K K  + QL    TLL   Q  +  CS+F    L+
Sbjct: 208 FDELQKTLNVRKSVLLMELEVNYGLKHKVLQSQLD---TLLQG-QESIKSCSNFTAQALN 263

Query: 303 LANKAEFLDLGYELMERLQGIVTRPHHLRPIQSSKI 338
              + E L +  ++ E+L  +  +   L P ++ ++
Sbjct: 264 HGTETEVLLVKKQMSEKLNELADQDFPLHPRENDQL 299


>gi|194248079 tripartite motif-containing 2 isoform 1 [Homo sapiens]
          Length = 771

 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 74/336 (22%), Positives = 129/336 (38%), Gaps = 77/336 (22%)

Query: 23  LVCPLCHVQYERPCLLDCFHDFCAGCLRG--RATDGRLTCPLCQHQTVL--KGPSGLPP- 77
           L+C +C  +Y+ P +L C H FC  CL+    A    L+CP+C+  ++L  KG + L   
Sbjct: 48  LICSICLERYKNPKVLPCLHTFCERCLQNYIPAHSLTLSCPVCRQTSILPEKGVAALQNN 107

Query: 78  --VDRLLQFLVDSSGDGVE--------AVRCANCDLECSEQDVET-TYFCNTCGQPLCAR 126
             +  L+  L  + G   E            A   L C   D     ++C +C   +C  
Sbjct: 108 FFITNLMDVLQRTPGSNAEESSILETVTAVAAGKPLSCPNHDGNVMEFYCQSCETAMCRE 167

Query: 127 CRDETHRARMFARHDIVALGQRSRDVPQKCTLHAEPYLLFSTDKKLLLCIRCFRDMQKES 186
           C +  H     A H  V L                                  +D+ ++ 
Sbjct: 168 CTEGEH-----AEHPTVPL----------------------------------KDVVEQH 188

Query: 187 RAHCVDLESAYVQGCERLEQAVLAVKALQTATREAIALLQAMVEEVRHSAAEEEDAIHAL 246
           +A               L+  + AV         A+  +  ++ ++ +  A   D IH+ 
Sbjct: 189 KA--------------SLQVQLDAVNKRLPEIDSALQFISEIIHQLTNQKASIVDDIHST 234

Query: 247 FGSMQDRLAERKALLLQAVQSQYEEKDKAFKEQLSHLATLLPTLQVHLVICSSF----LS 302
           F  +Q  L  RK++LL  ++  Y  K K  + QL    TLL   Q  +  CS+F    L+
Sbjct: 235 FDELQKTLNVRKSVLLMELEVNYGLKHKVLQSQLD---TLLQG-QESIKSCSNFTAQALN 290

Query: 303 LANKAEFLDLGYELMERLQGIVTRPHHLRPIQSSKI 338
              + E L +  ++ E+L  +  +   L P ++ ++
Sbjct: 291 HGTETEVLLVKKQMSEKLNELADQDFPLHPRENDQL 326


>gi|67089160 promyelocytic leukemia protein isoform 11 [Homo
           sapiens]
          Length = 781

 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 66/304 (21%), Positives = 118/304 (38%), Gaps = 24/304 (7%)

Query: 23  LVCPLCHVQYERPCLLDCFHDFCAGCLRGRATDGRLTCPLCQHQTVLKGPSGLPPVDRLL 82
           L C  C  + + P LL C H  C+GCL        + CP+CQ    L   +  P +D + 
Sbjct: 55  LRCQQCQAEAKCPKLLPCLHTLCSGCLEASG----MQCPICQAPWPLGADT--PALDNV- 107

Query: 83  QFLVDSSGDGVEAVR-CANCDLECSEQDVETTYFCNTCGQPLCARCRDE-----THRARM 136
               +S    +   R   +    C+       ++C  C Q LCA+C +       H AR 
Sbjct: 108 --FFESLQRRLSVYRQIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARP 165

Query: 137 FAR------HDIVALGQRSRDVPQKCTLHAEPYL--LFSTDKKLLLCIRCFRDMQKESRA 188
            A        + +   +++ ++      H  P L  ++       LC  C       S  
Sbjct: 166 LAELRNQSVREFLDGTRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSEL 225

Query: 189 HCVDLESAYVQGCERLEQAVLAVKALQTATREAIALLQAMVEEVRHSAAEEEDAIHALFG 248
            C D+ +   Q  E L+    A++   +A     A + A V ++  + AE E+ I     
Sbjct: 226 KC-DISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVR 284

Query: 249 SMQDRLAERKALLLQAVQSQYEEKDKAFKEQLSHLATLLPTLQVHLVICSSFLSLANKAE 308
            +   +  ++  LL+AV ++Y+   +    +L  L  +L  ++    +       A+  E
Sbjct: 285 QVVAHVRAQERELLEAVDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQE 344

Query: 309 FLDL 312
            LD+
Sbjct: 345 VLDM 348


>gi|67089157 promyelocytic leukemia protein isoform 2 [Homo sapiens]
          Length = 611

 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 66/304 (21%), Positives = 118/304 (38%), Gaps = 24/304 (7%)

Query: 23  LVCPLCHVQYERPCLLDCFHDFCAGCLRGRATDGRLTCPLCQHQTVLKGPSGLPPVDRLL 82
           L C  C  + + P LL C H  C+GCL        + CP+CQ    L   +  P +D + 
Sbjct: 55  LRCQQCQAEAKCPKLLPCLHTLCSGCLEASG----MQCPICQAPWPLGADT--PALDNV- 107

Query: 83  QFLVDSSGDGVEAVR-CANCDLECSEQDVETTYFCNTCGQPLCARCRDE-----THRARM 136
               +S    +   R   +    C+       ++C  C Q LCA+C +       H AR 
Sbjct: 108 --FFESLQRRLSVYRQIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARP 165

Query: 137 FAR------HDIVALGQRSRDVPQKCTLHAEPYL--LFSTDKKLLLCIRCFRDMQKESRA 188
            A        + +   +++ ++      H  P L  ++       LC  C       S  
Sbjct: 166 LAELRNQSVREFLDGTRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSEL 225

Query: 189 HCVDLESAYVQGCERLEQAVLAVKALQTATREAIALLQAMVEEVRHSAAEEEDAIHALFG 248
            C D+ +   Q  E L+    A++   +A     A + A V ++  + AE E+ I     
Sbjct: 226 KC-DISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVR 284

Query: 249 SMQDRLAERKALLLQAVQSQYEEKDKAFKEQLSHLATLLPTLQVHLVICSSFLSLANKAE 308
            +   +  ++  LL+AV ++Y+   +    +L  L  +L  ++    +       A+  E
Sbjct: 285 QVVAHVRAQERELLEAVDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQE 344

Query: 309 FLDL 312
            LD+
Sbjct: 345 VLDM 348


>gi|15451765 promyelocytic leukemia protein isoform 9 [Homo sapiens]
          Length = 829

 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 66/304 (21%), Positives = 118/304 (38%), Gaps = 24/304 (7%)

Query: 23  LVCPLCHVQYERPCLLDCFHDFCAGCLRGRATDGRLTCPLCQHQTVLKGPSGLPPVDRLL 82
           L C  C  + + P LL C H  C+GCL        + CP+CQ    L   +  P +D + 
Sbjct: 55  LRCQQCQAEAKCPKLLPCLHTLCSGCLEASG----MQCPICQAPWPLGADT--PALDNV- 107

Query: 83  QFLVDSSGDGVEAVR-CANCDLECSEQDVETTYFCNTCGQPLCARCRDE-----THRARM 136
               +S    +   R   +    C+       ++C  C Q LCA+C +       H AR 
Sbjct: 108 --FFESLQRRLSVYRQIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARP 165

Query: 137 FAR------HDIVALGQRSRDVPQKCTLHAEPYL--LFSTDKKLLLCIRCFRDMQKESRA 188
            A        + +   +++ ++      H  P L  ++       LC  C       S  
Sbjct: 166 LAELRNQSVREFLDGTRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSEL 225

Query: 189 HCVDLESAYVQGCERLEQAVLAVKALQTATREAIALLQAMVEEVRHSAAEEEDAIHALFG 248
            C D+ +   Q  E L+    A++   +A     A + A V ++  + AE E+ I     
Sbjct: 226 KC-DISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVR 284

Query: 249 SMQDRLAERKALLLQAVQSQYEEKDKAFKEQLSHLATLLPTLQVHLVICSSFLSLANKAE 308
            +   +  ++  LL+AV ++Y+   +    +L  L  +L  ++    +       A+  E
Sbjct: 285 QVVAHVRAQERELLEAVDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQE 344

Query: 309 FLDL 312
            LD+
Sbjct: 345 VLDM 348


>gi|67089154 promyelocytic leukemia protein isoform 8 [Homo sapiens]
          Length = 435

 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 66/304 (21%), Positives = 118/304 (38%), Gaps = 24/304 (7%)

Query: 23  LVCPLCHVQYERPCLLDCFHDFCAGCLRGRATDGRLTCPLCQHQTVLKGPSGLPPVDRLL 82
           L C  C  + + P LL C H  C+GCL        + CP+CQ    L   +  P +D + 
Sbjct: 55  LRCQQCQAEAKCPKLLPCLHTLCSGCLEASG----MQCPICQAPWPLGADT--PALDNV- 107

Query: 83  QFLVDSSGDGVEAVR-CANCDLECSEQDVETTYFCNTCGQPLCARCRDE-----THRARM 136
               +S    +   R   +    C+       ++C  C Q LCA+C +       H AR 
Sbjct: 108 --FFESLQRRLSVYRQIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARP 165

Query: 137 FAR------HDIVALGQRSRDVPQKCTLHAEPYL--LFSTDKKLLLCIRCFRDMQKESRA 188
            A        + +   +++ ++      H  P L  ++       LC  C       S  
Sbjct: 166 LAELRNQSVREFLDGTRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSEL 225

Query: 189 HCVDLESAYVQGCERLEQAVLAVKALQTATREAIALLQAMVEEVRHSAAEEEDAIHALFG 248
            C D+ +   Q  E L+    A++   +A     A + A V ++  + AE E+ I     
Sbjct: 226 KC-DISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVR 284

Query: 249 SMQDRLAERKALLLQAVQSQYEEKDKAFKEQLSHLATLLPTLQVHLVICSSFLSLANKAE 308
            +   +  ++  LL+AV ++Y+   +    +L  L  +L  ++    +       A+  E
Sbjct: 285 QVVAHVRAQERELLEAVDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQE 344

Query: 309 FLDL 312
            LD+
Sbjct: 345 VLDM 348


>gi|4505903 promyelocytic leukemia protein isoform 6 [Homo sapiens]
          Length = 633

 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 66/304 (21%), Positives = 118/304 (38%), Gaps = 24/304 (7%)

Query: 23  LVCPLCHVQYERPCLLDCFHDFCAGCLRGRATDGRLTCPLCQHQTVLKGPSGLPPVDRLL 82
           L C  C  + + P LL C H  C+GCL        + CP+CQ    L   +  P +D + 
Sbjct: 55  LRCQQCQAEAKCPKLLPCLHTLCSGCLEASG----MQCPICQAPWPLGADT--PALDNV- 107

Query: 83  QFLVDSSGDGVEAVR-CANCDLECSEQDVETTYFCNTCGQPLCARCRDE-----THRARM 136
               +S    +   R   +    C+       ++C  C Q LCA+C +       H AR 
Sbjct: 108 --FFESLQRRLSVYRQIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARP 165

Query: 137 FAR------HDIVALGQRSRDVPQKCTLHAEPYL--LFSTDKKLLLCIRCFRDMQKESRA 188
            A        + +   +++ ++      H  P L  ++       LC  C       S  
Sbjct: 166 LAELRNQSVREFLDGTRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSEL 225

Query: 189 HCVDLESAYVQGCERLEQAVLAVKALQTATREAIALLQAMVEEVRHSAAEEEDAIHALFG 248
            C D+ +   Q  E L+    A++   +A     A + A V ++  + AE E+ I     
Sbjct: 226 KC-DISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVR 284

Query: 249 SMQDRLAERKALLLQAVQSQYEEKDKAFKEQLSHLATLLPTLQVHLVICSSFLSLANKAE 308
            +   +  ++  LL+AV ++Y+   +    +L  L  +L  ++    +       A+  E
Sbjct: 285 QVVAHVRAQERELLEAVDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQE 344

Query: 309 FLDL 312
            LD+
Sbjct: 345 VLDM 348


>gi|15451775 promyelocytic leukemia protein isoform 7 [Homo sapiens]
          Length = 423

 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 66/304 (21%), Positives = 118/304 (38%), Gaps = 24/304 (7%)

Query: 23  LVCPLCHVQYERPCLLDCFHDFCAGCLRGRATDGRLTCPLCQHQTVLKGPSGLPPVDRLL 82
           L C  C  + + P LL C H  C+GCL        + CP+CQ    L   +  P +D + 
Sbjct: 55  LRCQQCQAEAKCPKLLPCLHTLCSGCLEASG----MQCPICQAPWPLGADT--PALDNV- 107

Query: 83  QFLVDSSGDGVEAVR-CANCDLECSEQDVETTYFCNTCGQPLCARCRDE-----THRARM 136
               +S    +   R   +    C+       ++C  C Q LCA+C +       H AR 
Sbjct: 108 --FFESLQRRLSVYRQIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARP 165

Query: 137 FAR------HDIVALGQRSRDVPQKCTLHAEPYL--LFSTDKKLLLCIRCFRDMQKESRA 188
            A        + +   +++ ++      H  P L  ++       LC  C       S  
Sbjct: 166 LAELRNQSVREFLDGTRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSEL 225

Query: 189 HCVDLESAYVQGCERLEQAVLAVKALQTATREAIALLQAMVEEVRHSAAEEEDAIHALFG 248
            C D+ +   Q  E L+    A++   +A     A + A V ++  + AE E+ I     
Sbjct: 226 KC-DISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVR 284

Query: 249 SMQDRLAERKALLLQAVQSQYEEKDKAFKEQLSHLATLLPTLQVHLVICSSFLSLANKAE 308
            +   +  ++  LL+AV ++Y+   +    +L  L  +L  ++    +       A+  E
Sbjct: 285 QVVAHVRAQERELLEAVDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQE 344

Query: 309 FLDL 312
            LD+
Sbjct: 345 VLDM 348


>gi|15451779 promyelocytic leukemia protein isoform 10 [Homo
           sapiens]
          Length = 585

 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 66/304 (21%), Positives = 118/304 (38%), Gaps = 24/304 (7%)

Query: 23  LVCPLCHVQYERPCLLDCFHDFCAGCLRGRATDGRLTCPLCQHQTVLKGPSGLPPVDRLL 82
           L C  C  + + P LL C H  C+GCL        + CP+CQ    L   +  P +D + 
Sbjct: 55  LRCQQCQAEAKCPKLLPCLHTLCSGCLEASG----MQCPICQAPWPLGADT--PALDNV- 107

Query: 83  QFLVDSSGDGVEAVR-CANCDLECSEQDVETTYFCNTCGQPLCARCRDE-----THRARM 136
               +S    +   R   +    C+       ++C  C Q LCA+C +       H AR 
Sbjct: 108 --FFESLQRRLSVYRQIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARP 165

Query: 137 FAR------HDIVALGQRSRDVPQKCTLHAEPYL--LFSTDKKLLLCIRCFRDMQKESRA 188
            A        + +   +++ ++      H  P L  ++       LC  C       S  
Sbjct: 166 LAELRNQSVREFLDGTRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSEL 225

Query: 189 HCVDLESAYVQGCERLEQAVLAVKALQTATREAIALLQAMVEEVRHSAAEEEDAIHALFG 248
            C D+ +   Q  E L+    A++   +A     A + A V ++  + AE E+ I     
Sbjct: 226 KC-DISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVR 284

Query: 249 SMQDRLAERKALLLQAVQSQYEEKDKAFKEQLSHLATLLPTLQVHLVICSSFLSLANKAE 308
            +   +  ++  LL+AV ++Y+   +    +L  L  +L  ++    +       A+  E
Sbjct: 285 QVVAHVRAQERELLEAVDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQE 344

Query: 309 FLDL 312
            LD+
Sbjct: 345 VLDM 348


>gi|67089149 promyelocytic leukemia protein isoform 1 [Homo sapiens]
          Length = 882

 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 66/304 (21%), Positives = 118/304 (38%), Gaps = 24/304 (7%)

Query: 23  LVCPLCHVQYERPCLLDCFHDFCAGCLRGRATDGRLTCPLCQHQTVLKGPSGLPPVDRLL 82
           L C  C  + + P LL C H  C+GCL        + CP+CQ    L   +  P +D + 
Sbjct: 55  LRCQQCQAEAKCPKLLPCLHTLCSGCLEASG----MQCPICQAPWPLGADT--PALDNV- 107

Query: 83  QFLVDSSGDGVEAVR-CANCDLECSEQDVETTYFCNTCGQPLCARCRDE-----THRARM 136
               +S    +   R   +    C+       ++C  C Q LCA+C +       H AR 
Sbjct: 108 --FFESLQRRLSVYRQIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARP 165

Query: 137 FAR------HDIVALGQRSRDVPQKCTLHAEPYL--LFSTDKKLLLCIRCFRDMQKESRA 188
            A        + +   +++ ++      H  P L  ++       LC  C       S  
Sbjct: 166 LAELRNQSVREFLDGTRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSEL 225

Query: 189 HCVDLESAYVQGCERLEQAVLAVKALQTATREAIALLQAMVEEVRHSAAEEEDAIHALFG 248
            C D+ +   Q  E L+    A++   +A     A + A V ++  + AE E+ I     
Sbjct: 226 KC-DISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVR 284

Query: 249 SMQDRLAERKALLLQAVQSQYEEKDKAFKEQLSHLATLLPTLQVHLVICSSFLSLANKAE 308
            +   +  ++  LL+AV ++Y+   +    +L  L  +L  ++    +       A+  E
Sbjct: 285 QVVAHVRAQERELLEAVDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQE 344

Query: 309 FLDL 312
            LD+
Sbjct: 345 VLDM 348


>gi|109637788 promyelocytic leukemia protein isoform 5 [Homo
           sapiens]
          Length = 560

 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 66/304 (21%), Positives = 118/304 (38%), Gaps = 24/304 (7%)

Query: 23  LVCPLCHVQYERPCLLDCFHDFCAGCLRGRATDGRLTCPLCQHQTVLKGPSGLPPVDRLL 82
           L C  C  + + P LL C H  C+GCL        + CP+CQ    L   +  P +D + 
Sbjct: 55  LRCQQCQAEAKCPKLLPCLHTLCSGCLEASG----MQCPICQAPWPLGADT--PALDNV- 107

Query: 83  QFLVDSSGDGVEAVR-CANCDLECSEQDVETTYFCNTCGQPLCARCRDE-----THRARM 136
               +S    +   R   +    C+       ++C  C Q LCA+C +       H AR 
Sbjct: 108 --FFESLQRRLSVYRQIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARP 165

Query: 137 FAR------HDIVALGQRSRDVPQKCTLHAEPYL--LFSTDKKLLLCIRCFRDMQKESRA 188
            A        + +   +++ ++      H  P L  ++       LC  C       S  
Sbjct: 166 LAELRNQSVREFLDGTRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSEL 225

Query: 189 HCVDLESAYVQGCERLEQAVLAVKALQTATREAIALLQAMVEEVRHSAAEEEDAIHALFG 248
            C D+ +   Q  E L+    A++   +A     A + A V ++  + AE E+ I     
Sbjct: 226 KC-DISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVR 284

Query: 249 SMQDRLAERKALLLQAVQSQYEEKDKAFKEQLSHLATLLPTLQVHLVICSSFLSLANKAE 308
            +   +  ++  LL+AV ++Y+   +    +L  L  +L  ++    +       A+  E
Sbjct: 285 QVVAHVRAQERELLEAVDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQE 344

Query: 309 FLDL 312
            LD+
Sbjct: 345 VLDM 348


>gi|32454739 tripartite motif-containing 3 [Homo sapiens]
          Length = 744

 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 74/341 (21%), Positives = 129/341 (37%), Gaps = 74/341 (21%)

Query: 18  PSIHP-----LVCPLCHVQYERPCLLDCFHDFCAGCLRG--RATDGRLTCPLCQHQTVL- 69
           P + P     LVC +C  +Y+ P +L C H FC  CL+    A    L+CP+C+  ++L 
Sbjct: 10  PEVQPMDKQFLVCSICLDRYQCPKVLPCLHTFCERCLQNYIPAQSLTLSCPVCRQTSILP 69

Query: 70  -KGPSGLPP---VDRLLQFLVDSSGDGVEAVR-------CANCDLECSEQDVET-TYFCN 117
            +G S L     +  L++  +  + DG             A   L C   + +T  ++C 
Sbjct: 70  EQGVSALQNNFFISSLME-AMQQAPDGAHDPEDPHPLSVVAGRPLSCPNHEGKTMEFYCE 128

Query: 118 TCGQPLCARCRDETHRARMFARHDIVALGQRSRDVPQKCTLHAEPYLLFSTDKKLLLCIR 177
            C   +C  CR   HR      H  V L                                
Sbjct: 129 ACETAMCGECRAGEHR-----EHGTVLL-------------------------------- 151

Query: 178 CFRDMQKESRAHCVDLESAYVQGCERLEQAVLAVKALQTATREAIALLQAMVEEVRHSAA 237
             RD+ ++ +A               L++ + AV+        AIAL+  + ++++   A
Sbjct: 152 --RDVVEQHKA--------------ALQRQLEAVRGRLPQLSAAIALVGGISQQLQERKA 195

Query: 238 EEEDAIHALFGSMQDRLAERKALLLQAVQSQYEEKDKAFKEQLSHLATLLPTLQVHLVIC 297
           E    I A F  ++  L +RK  L+  +++    K K  + QL  L      +       
Sbjct: 196 EALAQISAAFEDLEQALQQRKQALVSDLETICGAKQKVLQSQLDTLRQGQEHIGSSCSFA 255

Query: 298 SSFLSLANKAEFLDLGYELMERLQGIVTRPHHLRPIQSSKI 338
              L L +  E L +   + ERL  +  +    RP +++++
Sbjct: 256 EQALRLGSAPEVLLVRKHMRERLAALAAQAFPERPHENAQL 296


>gi|32454737 tripartite motif-containing 3 [Homo sapiens]
          Length = 744

 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 74/341 (21%), Positives = 129/341 (37%), Gaps = 74/341 (21%)

Query: 18  PSIHP-----LVCPLCHVQYERPCLLDCFHDFCAGCLRG--RATDGRLTCPLCQHQTVL- 69
           P + P     LVC +C  +Y+ P +L C H FC  CL+    A    L+CP+C+  ++L 
Sbjct: 10  PEVQPMDKQFLVCSICLDRYQCPKVLPCLHTFCERCLQNYIPAQSLTLSCPVCRQTSILP 69

Query: 70  -KGPSGLPP---VDRLLQFLVDSSGDGVEAVR-------CANCDLECSEQDVET-TYFCN 117
            +G S L     +  L++  +  + DG             A   L C   + +T  ++C 
Sbjct: 70  EQGVSALQNNFFISSLME-AMQQAPDGAHDPEDPHPLSVVAGRPLSCPNHEGKTMEFYCE 128

Query: 118 TCGQPLCARCRDETHRARMFARHDIVALGQRSRDVPQKCTLHAEPYLLFSTDKKLLLCIR 177
            C   +C  CR   HR      H  V L                                
Sbjct: 129 ACETAMCGECRAGEHR-----EHGTVLL-------------------------------- 151

Query: 178 CFRDMQKESRAHCVDLESAYVQGCERLEQAVLAVKALQTATREAIALLQAMVEEVRHSAA 237
             RD+ ++ +A               L++ + AV+        AIAL+  + ++++   A
Sbjct: 152 --RDVVEQHKA--------------ALQRQLEAVRGRLPQLSAAIALVGGISQQLQERKA 195

Query: 238 EEEDAIHALFGSMQDRLAERKALLLQAVQSQYEEKDKAFKEQLSHLATLLPTLQVHLVIC 297
           E    I A F  ++  L +RK  L+  +++    K K  + QL  L      +       
Sbjct: 196 EALAQISAAFEDLEQALQQRKQALVSDLETICGAKQKVLQSQLDTLRQGQEHIGSSCSFA 255

Query: 298 SSFLSLANKAEFLDLGYELMERLQGIVTRPHHLRPIQSSKI 338
              L L +  E L +   + ERL  +  +    RP +++++
Sbjct: 256 EQALRLGSAPEVLLVRKHMRERLAALAAQAFPERPHENAQL 296


>gi|5032179 tripartite motif-containing 28 protein [Homo sapiens]
          Length = 835

 Score = 64.3 bits (155), Expect = 3e-10
 Identities = 96/406 (23%), Positives = 153/406 (37%), Gaps = 66/406 (16%)

Query: 25  CPLCHVQYE---RPCLLDCFHDFCAGCLR-------------GRATDGRLT-CPLCQHQT 67
           C +C  +      P LL C H  C+ CL              G A DG +  CP+C+ Q 
Sbjct: 65  CGVCRERLRPEREPRLLPCLHSACSACLGPAAPAAANSSGDGGAAGDGTVVDCPVCKQQC 124

Query: 68  VLKGPSGLPPVDRLLQFLVDSSGD--GVEAVRCANCDLECSEQDVETTYFCNTCGQPLCA 125
             K        D +  + +  SG     +A     C   C E +   T +C  C +PLC 
Sbjct: 125 FSK--------DIVENYFMRDSGSKAATDAQDANQCCTSC-EDNAPATSYCVECSEPLCE 175

Query: 126 RCRDETHRARMFARHDIVALG-QRSRDVPQK--CTLHA-EPYLLFSTDKKLLLCIRCFRD 181
            C +   R +    H + + G  +SRD  +   C +H  EP +LF      L C  C  +
Sbjct: 176 TCVEAHQRVKYTKDHTVRSTGPAKSRDGERTVYCNVHKHEPLVLFCESCDTLTCRDCQLN 235

Query: 182 MQKESRAHCVDLESAYVQGCERLEQAVLAVKALQTATREAIALLQAMVEEVRHSAAEEED 241
             K       D +  +++   R ++ +LA  +L     +  A LQ   +EVR S  +  D
Sbjct: 236 AHK-------DHQYQFLEDAVRNQRKLLA--SLVKRLGDKHATLQKSTKEVRSSIRQVSD 286

Query: 242 A-------IHALFGSMQDRLAERKALLLQAVQSQYEEKDKAFKEQLSHLATLLPTLQVHL 294
                   +      +   L +R  +L+   Q   E + +  + Q     T +   Q H+
Sbjct: 287 VQKRVQVDVKMAILQIMKELNKRGRVLVNDAQKVTEGQQERLERQ-HWTMTKIQKHQEHI 345

Query: 295 VICSSF-LSLANKAEFL---DLGYELMERLQGIVTRPHHLRPIQSSKIASDHRAEFARCL 350
           +  +S+ L   N    L    L Y  + R   ++  P  + P    K   D  A + +  
Sbjct: 346 LRFASWALESDNNTALLLSKKLIYFQLHRALKMIVDP--VEPHGEMKFQWDLNA-WTKSA 402

Query: 351 EPLLLLGPRRVAAAASGANTLAGGLGPKALTGPHCPSPVGKM-SGS 395
           E        ++ A   G N+     GP  +  P  P P+ K  SGS
Sbjct: 403 EAF-----GKIVAERPGTNS----TGPAPMAPPRAPGPLSKQGSGS 439


>gi|224548923 tripartite motif-containing 45 isoform 2 [Homo
           sapiens]
          Length = 562

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 87/369 (23%), Positives = 138/369 (37%), Gaps = 58/369 (15%)

Query: 25  CPLCHVQYERPCLLDCFHDFCAGCL-----------RGRATDGR---------------- 57
           CPLC   ++ P LL C H  C  CL           RG  +D                  
Sbjct: 29  CPLCLGLFKAPRLLPCLHTVCTTCLEQLEPFSVVDIRGGDSDTSSEGSIFQELKPRSLQS 88

Query: 58  ---LTCPLCQHQTVLK-GPSGLPPVDRLLQ---FLVDSSGDGVEAVRCANCDLECSEQDV 110
              + CP+C  Q  L  G      +D L      L    G+G   V    CDL C++++V
Sbjct: 89  QIGILCPVCDAQVDLPMGGVKALTIDHLAVNDVMLESLRGEGQGLV----CDL-CNDREV 143

Query: 111 ETTYFCNTCGQPLCARCRDETHRARMFARHDIVAL----GQRSRDVPQKCTLH-AEPYLL 165
           E    C TC   LC  C     R +    H +V L    G      P  C +H AE   L
Sbjct: 144 EKR--CQTCKANLCHFCCQAHRRQKKTTYHTMVDLKDLKGYSRIGKPILCPVHPAEELRL 201

Query: 166 FSTDKKLLLCIRCFRDMQKESRAHCVDLESAYVQG-----CERLEQAVLAVKALQTATRE 220
           F       +C  C   +  E R H  D  S  +        E L+     V+AL+ A  +
Sbjct: 202 FCEFCDRPVCQDC---VVGEHREHPCDFTSNVIHKHGDSVWELLKGTQPHVEALEEALAQ 258

Query: 221 AIALLQAMVEEVRHSAAEEEDAIHALFGSMQDRLAERKALLLQAVQSQYEEKDKAFKEQL 280
              +  A+ + V   AA+          +++    E +  LL+ ++    +K+ + + Q 
Sbjct: 259 IHIINSALQKRVEAVAADVRTFSEGYIKAIE----EHRDKLLKQLEDIRAQKENSLQLQK 314

Query: 281 SHLATLLPTLQVHLVICSSFLSLANKAEFLDLGYELMERLQGIVTRPHHLRPIQSSKIAS 340
           + L  LL  ++  +      L+  +  E L     ++ERL+ +    +  RP  + KI  
Sbjct: 315 AQLEQLLADMRTGVEFTEHLLTSGSDLEILITKRVVVERLRKLNKVQYSTRPGVNDKIRF 374

Query: 341 DHRAEFARC 349
             + +  +C
Sbjct: 375 CPQEKAGQC 383


>gi|224548921 tripartite motif-containing 45 isoform 1 [Homo
           sapiens]
          Length = 580

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 87/369 (23%), Positives = 138/369 (37%), Gaps = 58/369 (15%)

Query: 25  CPLCHVQYERPCLLDCFHDFCAGCL-----------RGRATDGR---------------- 57
           CPLC   ++ P LL C H  C  CL           RG  +D                  
Sbjct: 29  CPLCLGLFKAPRLLPCLHTVCTTCLEQLEPFSVVDIRGGDSDTSSEGSIFQELKPRSLQS 88

Query: 58  ---LTCPLCQHQTVLK-GPSGLPPVDRLLQ---FLVDSSGDGVEAVRCANCDLECSEQDV 110
              + CP+C  Q  L  G      +D L      L    G+G   V    CDL C++++V
Sbjct: 89  QIGILCPVCDAQVDLPMGGVKALTIDHLAVNDVMLESLRGEGQGLV----CDL-CNDREV 143

Query: 111 ETTYFCNTCGQPLCARCRDETHRARMFARHDIVAL----GQRSRDVPQKCTLH-AEPYLL 165
           E    C TC   LC  C     R +    H +V L    G      P  C +H AE   L
Sbjct: 144 EKR--CQTCKANLCHFCCQAHRRQKKTTYHTMVDLKDLKGYSRIGKPILCPVHPAEELRL 201

Query: 166 FSTDKKLLLCIRCFRDMQKESRAHCVDLESAYVQG-----CERLEQAVLAVKALQTATRE 220
           F       +C  C   +  E R H  D  S  +        E L+     V+AL+ A  +
Sbjct: 202 FCEFCDRPVCQDC---VVGEHREHPCDFTSNVIHKHGDSVWELLKGTQPHVEALEEALAQ 258

Query: 221 AIALLQAMVEEVRHSAAEEEDAIHALFGSMQDRLAERKALLLQAVQSQYEEKDKAFKEQL 280
              +  A+ + V   AA+          +++    E +  LL+ ++    +K+ + + Q 
Sbjct: 259 IHIINSALQKRVEAVAADVRTFSEGYIKAIE----EHRDKLLKQLEDIRAQKENSLQLQK 314

Query: 281 SHLATLLPTLQVHLVICSSFLSLANKAEFLDLGYELMERLQGIVTRPHHLRPIQSSKIAS 340
           + L  LL  ++  +      L+  +  E L     ++ERL+ +    +  RP  + KI  
Sbjct: 315 AQLEQLLADMRTGVEFTEHLLTSGSDLEILITKRVVVERLRKLNKVQYSTRPGVNDKIRF 374

Query: 341 DHRAEFARC 349
             + +  +C
Sbjct: 375 CPQEKAGQC 383


>gi|78482627 ring finger protein 30 isoform 1 [Homo sapiens]
          Length = 400

 Score = 56.6 bits (135), Expect = 7e-08
 Identities = 66/291 (22%), Positives = 113/291 (38%), Gaps = 37/291 (12%)

Query: 6   FGPLEGPSSLDAPSIHPLVCPLCHVQYERPC-LLDCFHDFCAGCL-------------RG 51
           F PL G +         L+CP+C   + +P  +L C H+ C  C              RG
Sbjct: 7   FKPLLGDAHSMDNLEKQLICPICLEMFSKPVVILPCQHNLCRKCANDVFQASNPLWQSRG 66

Query: 52  RAT---DGRLTCPLCQHQTVL--KGPSGLPP---VDRLLQFLVDSSGDGVEAVRCANCDL 103
             T    GR  CP C+H+ VL   G  GL     V+ ++      S   + +   A   L
Sbjct: 67  STTVSSGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESSRPLHSK--AEQHL 124

Query: 104 ECSEQDVE-TTYFCNTCGQPLCARCR-DETHRARMFARHDIVALGQRSRDVPQKCTLHAE 161
            C E + E    +C +C  P C+ C+    H+    A    +   Q+ +D+         
Sbjct: 125 MCEEHEEEKINIYCLSCEVPTCSLCKVFGAHKDCEVAPLPTIYKRQKKQDLT-------- 176

Query: 162 PYLLFSTDKKLLLCIRCFRDMQKESRAHCVDLESAYVQGCERLEQAVLAVKALQTATREA 221
             LL   +        C  D+   S    +  ++  +   E L   +  + A     +  
Sbjct: 177 --LLPRLECSGTNTTYCSLDLPSSSDPPILASQNTKIIDSE-LSDGIAMLVAGNDRVQAV 233

Query: 222 IALLQAMVEEVRHSAAEEEDAIHALFGSMQDRLAERKALLLQAVQSQYEEK 272
           I  ++ + + +  ++  ++  ++  F S+   L ERK  LLQA+  + EEK
Sbjct: 234 ITQMEEVCQTIEDNSRRQKQLLNQRFESLCAVLEERKGELLQALAREQEEK 284


>gi|74027251 tripartite motif-containing 33 protein isoform beta
           [Homo sapiens]
          Length = 1110

 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 75/333 (22%), Positives = 117/333 (35%), Gaps = 68/333 (20%)

Query: 3   GAIFGPLEGPSSLDAP--SIHPL---------VCPLCHVQYE-----RPCLLDCFHDFCA 46
           GA+  P   P+S  AP  S  P           C +C    +      P LL C H FC 
Sbjct: 92  GAVSTPAPAPASAPAPGPSAGPPPGPPASLLDTCAVCQQSLQSRREAEPKLLPCLHSFCL 151

Query: 47  GCL------------RGRATD----GRLTCPLCQHQTVLKGPSGLPPVDRLLQFLV---- 86
            CL             G   D    G + CP+C+ +           +D +  + V    
Sbjct: 152 RCLPEPERQLSVPIPGGSNGDIQQVGVIRCPVCRQE--------CRQIDLVDNYFVKDTS 203

Query: 87  --DSSGDGVEAVRCANCDLECSEQDVETTYFCNTCGQPLCARCRDETHRARMFARH---- 140
              SS D      C +C     E +     FC  CG+ LC  C +   R +    H    
Sbjct: 204 EAPSSSDEKSEQVCTSC-----EDNASAVGFCVECGEWLCKTCIEAHQRVKFTKDHLIRK 258

Query: 141 ------DIVALGQRSRDVPQKCTLHAEPYL-LFSTDKKLLLCIRCFRDMQKESRAHCVDL 193
                  + A GQR    P  C +H +  L LF      L C  C     KE R     L
Sbjct: 259 KEDVSESVGASGQR----PVFCPVHKQEQLKLFCETCDRLTCRDCQLLEHKEHRYQF--L 312

Query: 194 ESAYVQGCERLEQAVLAVKALQTATREAIALLQAMVEEVRHSAAEEEDAIHALFGSMQDR 253
           E A+      +E  +  +   +     A   +Q  ++EV  +    E  I     ++ + 
Sbjct: 313 EEAFQNQKGAIENLLAKLLEKKNYVHFAATQVQNRIKEVNETNKRVEQEIKVAIFTLINE 372

Query: 254 LAERKALLLQAVQSQYEEKDKAFKEQLSHLATL 286
           + ++   LLQ +++  +E+     +Q + +  L
Sbjct: 373 INKKGKSLLQQLENVTKERQMKLLQQQNDITGL 405


>gi|74027249 tripartite motif-containing 33 protein isoform alpha
           [Homo sapiens]
          Length = 1127

 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 75/333 (22%), Positives = 117/333 (35%), Gaps = 68/333 (20%)

Query: 3   GAIFGPLEGPSSLDAP--SIHPL---------VCPLCHVQYE-----RPCLLDCFHDFCA 46
           GA+  P   P+S  AP  S  P           C +C    +      P LL C H FC 
Sbjct: 92  GAVSTPAPAPASAPAPGPSAGPPPGPPASLLDTCAVCQQSLQSRREAEPKLLPCLHSFCL 151

Query: 47  GCL------------RGRATD----GRLTCPLCQHQTVLKGPSGLPPVDRLLQFLV---- 86
            CL             G   D    G + CP+C+ +           +D +  + V    
Sbjct: 152 RCLPEPERQLSVPIPGGSNGDIQQVGVIRCPVCRQE--------CRQIDLVDNYFVKDTS 203

Query: 87  --DSSGDGVEAVRCANCDLECSEQDVETTYFCNTCGQPLCARCRDETHRARMFARH---- 140
              SS D      C +C     E +     FC  CG+ LC  C +   R +    H    
Sbjct: 204 EAPSSSDEKSEQVCTSC-----EDNASAVGFCVECGEWLCKTCIEAHQRVKFTKDHLIRK 258

Query: 141 ------DIVALGQRSRDVPQKCTLHAEPYL-LFSTDKKLLLCIRCFRDMQKESRAHCVDL 193
                  + A GQR    P  C +H +  L LF      L C  C     KE R     L
Sbjct: 259 KEDVSESVGASGQR----PVFCPVHKQEQLKLFCETCDRLTCRDCQLLEHKEHRYQF--L 312

Query: 194 ESAYVQGCERLEQAVLAVKALQTATREAIALLQAMVEEVRHSAAEEEDAIHALFGSMQDR 253
           E A+      +E  +  +   +     A   +Q  ++EV  +    E  I     ++ + 
Sbjct: 313 EEAFQNQKGAIENLLAKLLEKKNYVHFAATQVQNRIKEVNETNKRVEQEIKVAIFTLINE 372

Query: 254 LAERKALLLQAVQSQYEEKDKAFKEQLSHLATL 286
           + ++   LLQ +++  +E+     +Q + +  L
Sbjct: 373 INKKGKSLLQQLENVTKERQMKLLQQQNDITGL 405


>gi|15208643 ADP-ribosylation factor domain protein 1 isoform gamma
           [Homo sapiens]
          Length = 546

 Score = 53.5 bits (127), Expect = 6e-07
 Identities = 65/303 (21%), Positives = 107/303 (35%), Gaps = 38/303 (12%)

Query: 35  PCLLDCFHDFCAGCLRGRATDGR-LTCPLCQHQTVLKGPSG----------LPPVDRLLQ 83
           P LL C H  C  CL      GR + CP  +  T L G SG          L  ++RL  
Sbjct: 46  PRLLLCGHTVCHDCLTRLPLHGRAIRCPFDRQVTDL-GDSGVWGLKKNFALLELLERLQN 104

Query: 84  FLVDSSGDGVEAVRCANCDL-ECSEQDVE-TTYFCNTCGQPLCARCRDETHRARMFARHD 141
             +   G   E++  +   +  C E +    + +C  C   LC+ C   TH  +  A+H 
Sbjct: 105 GPIGQYGAAEESIGISGESIIRCDEDEAHLASVYCTVCATHLCSECSQVTHSTKTLAKHR 164

Query: 142 IVALGQRSRDVPQKCTLHAEPYLLF-----STDKKLLLCIRCFRDMQKESRAHCVDLESA 196
            V L  +  +    C+ H    + F           L+C  C    + +   H V    A
Sbjct: 165 RVPLADKPHE-KTMCSQHQVHAIEFVCLEEGCQTSPLMCCVCKEYGKHQGHKHSVLEPEA 223

Query: 197 YVQGCERLEQAVLA---VKALQTATREAIALLQ---------------AMVEEVRHSAAE 238
                  L+ A       + +   +R+ + ++Q               A  E V  +A  
Sbjct: 224 NQIRASILDMAHCIRTFTEEISDYSRKLVGIVQHIEGGEQIVEDGIGMAHTEHVPGTAEN 283

Query: 239 EEDAIHALFGSMQDRLAERKALLLQAVQSQYEEKDKAFKEQLSHLATLLPTLQVHLVICS 298
               I A F  + + L  ++ + L  V +   EK    ++Q   +  LL  +    + C 
Sbjct: 284 ARSCIRAYFYDLHETLCRQEEMALSVVDAHVREKLIWLRQQQEDMTILLSEVSAACLHCE 343

Query: 299 SFL 301
             L
Sbjct: 344 KTL 346


>gi|15208641 ADP-ribosylation factor domain protein 1 isoform beta
           [Homo sapiens]
          Length = 569

 Score = 53.5 bits (127), Expect = 6e-07
 Identities = 65/303 (21%), Positives = 107/303 (35%), Gaps = 38/303 (12%)

Query: 35  PCLLDCFHDFCAGCLRGRATDGR-LTCPLCQHQTVLKGPSG----------LPPVDRLLQ 83
           P LL C H  C  CL      GR + CP  +  T L G SG          L  ++RL  
Sbjct: 46  PRLLLCGHTVCHDCLTRLPLHGRAIRCPFDRQVTDL-GDSGVWGLKKNFALLELLERLQN 104

Query: 84  FLVDSSGDGVEAVRCANCDL-ECSEQDVE-TTYFCNTCGQPLCARCRDETHRARMFARHD 141
             +   G   E++  +   +  C E +    + +C  C   LC+ C   TH  +  A+H 
Sbjct: 105 GPIGQYGAAEESIGISGESIIRCDEDEAHLASVYCTVCATHLCSECSQVTHSTKTLAKHR 164

Query: 142 IVALGQRSRDVPQKCTLHAEPYLLF-----STDKKLLLCIRCFRDMQKESRAHCVDLESA 196
            V L  +  +    C+ H    + F           L+C  C    + +   H V    A
Sbjct: 165 RVPLADKPHE-KTMCSQHQVHAIEFVCLEEGCQTSPLMCCVCKEYGKHQGHKHSVLEPEA 223

Query: 197 YVQGCERLEQAVLA---VKALQTATREAIALLQ---------------AMVEEVRHSAAE 238
                  L+ A       + +   +R+ + ++Q               A  E V  +A  
Sbjct: 224 NQIRASILDMAHCIRTFTEEISDYSRKLVGIVQHIEGGEQIVEDGIGMAHTEHVPGTAEN 283

Query: 239 EEDAIHALFGSMQDRLAERKALLLQAVQSQYEEKDKAFKEQLSHLATLLPTLQVHLVICS 298
               I A F  + + L  ++ + L  V +   EK    ++Q   +  LL  +    + C 
Sbjct: 284 ARSCIRAYFYDLHETLCRQEEMALSVVDAHVREKLIWLRQQQEDMTILLSEVSAACLHCE 343

Query: 299 SFL 301
             L
Sbjct: 344 KTL 346


>gi|4502197 ADP-ribosylation factor domain protein 1 isoform alpha
           [Homo sapiens]
          Length = 574

 Score = 53.5 bits (127), Expect = 6e-07
 Identities = 65/303 (21%), Positives = 107/303 (35%), Gaps = 38/303 (12%)

Query: 35  PCLLDCFHDFCAGCLRGRATDGR-LTCPLCQHQTVLKGPSG----------LPPVDRLLQ 83
           P LL C H  C  CL      GR + CP  +  T L G SG          L  ++RL  
Sbjct: 46  PRLLLCGHTVCHDCLTRLPLHGRAIRCPFDRQVTDL-GDSGVWGLKKNFALLELLERLQN 104

Query: 84  FLVDSSGDGVEAVRCANCDL-ECSEQDVE-TTYFCNTCGQPLCARCRDETHRARMFARHD 141
             +   G   E++  +   +  C E +    + +C  C   LC+ C   TH  +  A+H 
Sbjct: 105 GPIGQYGAAEESIGISGESIIRCDEDEAHLASVYCTVCATHLCSECSQVTHSTKTLAKHR 164

Query: 142 IVALGQRSRDVPQKCTLHAEPYLLF-----STDKKLLLCIRCFRDMQKESRAHCVDLESA 196
            V L  +  +    C+ H    + F           L+C  C    + +   H V    A
Sbjct: 165 RVPLADKPHE-KTMCSQHQVHAIEFVCLEEGCQTSPLMCCVCKEYGKHQGHKHSVLEPEA 223

Query: 197 YVQGCERLEQAVLA---VKALQTATREAIALLQ---------------AMVEEVRHSAAE 238
                  L+ A       + +   +R+ + ++Q               A  E V  +A  
Sbjct: 224 NQIRASILDMAHCIRTFTEEISDYSRKLVGIVQHIEGGEQIVEDGIGMAHTEHVPGTAEN 283

Query: 239 EEDAIHALFGSMQDRLAERKALLLQAVQSQYEEKDKAFKEQLSHLATLLPTLQVHLVICS 298
               I A F  + + L  ++ + L  V +   EK    ++Q   +  LL  +    + C 
Sbjct: 284 ARSCIRAYFYDLHETLCRQEEMALSVVDAHVREKLIWLRQQQEDMTILLSEVSAACLHCE 343

Query: 299 SFL 301
             L
Sbjct: 344 KTL 346


>gi|21630277 tripartite motif-containing 11 [Homo sapiens]
          Length = 468

 Score = 53.1 bits (126), Expect = 7e-07
 Identities = 61/232 (26%), Positives = 88/232 (37%), Gaps = 30/232 (12%)

Query: 87  DSSGDGVEAVRCANCDLECSEQDVETTY---FCNTC-----GQP----LCARCRDETHRA 134
           D S +  E   CA C L+     V T     FC  C     GQP     C  CR+ + + 
Sbjct: 5   DLSTNLQEEATCAIC-LDYFTDPVMTDCGHNFCRECIRRCWGQPEGPYACPECRELSPQR 63

Query: 135 RMFARHDIVALGQRSR------DVPQK-CTLHAEPYLLFSTDKKLLLCIRCFRDMQKESR 187
            +     +  + + +R       VPQ  C  H EP   F  D+  LLC  C R    E  
Sbjct: 64  NLRPNRPLAKMAEMARRLHPPSPVPQGVCPAHREPLAAFCGDELRLLCAACERS--GEHW 121

Query: 188 AHCV--------DLESAYVQGCERLEQAVLAVKALQTATREAIALLQAMVEEVRHSAAEE 239
           AH V        DL++   +  E L + +      Q    E   L Q MVE  R +   E
Sbjct: 122 AHRVRPLQDAAEDLKAKLEKSLEHLRKQMQDALLFQAQADETCVLWQKMVESQRQNVLGE 181

Query: 240 EDAIHALFGSMQDRLAERKALLLQAVQSQYEEKDKAFKEQLSHLATLLPTLQ 291
            + +  L    + +L +R       V  +  E      +Q +HLA L+  L+
Sbjct: 182 FERLRRLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQSAHLAELIAELE 233


>gi|134288906 tripartite motif-containing 67 [Homo sapiens]
          Length = 783

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 76/364 (20%), Positives = 135/364 (37%), Gaps = 66/364 (18%)

Query: 46  AGCLRGRATDGRLTCPLCQHQTVL--KGPSGLPPVDRLLQFLVDSSGDGVEAVR------ 97
           A C    ++   +TCP C     L  +G  G    +RLL+ +V     G  AV       
Sbjct: 145 AACSSLSSSSSSITCPQCHRSASLDHRGLRGFQR-NRLLEAIVQRYQQGRGAVPGTSAAA 203

Query: 98  ----CANCDLECSEQDVETTYFCNTCGQPLCARCRDETHRAR-MFARHDIVAL------- 145
               C  CD    E        C  C    C+ C+ + H +R  FA+H +V         
Sbjct: 204 AVAICQLCDRTPPEP---AATLCEQCDVLYCSACQLKCHPSRGPFAKHRLVQPPPPPPPP 260

Query: 146 ---------------------------------GQRSRDVPQKCTLHAEPYLLFSTDKKL 172
                                            G  +R  P       E Y ++    + 
Sbjct: 261 AEAASGPTGTAQGAPSGGGGCKSPGGAGAGATGGSTARKFPTCPEHEMENYSMYCVSCRT 320

Query: 173 LLCIRCFRDMQKESRAHCVDLESAYVQGCERLEQAVLAVKALQTATREAIALLQAMVEEV 232
            +C  C  +  + ++     L + + Q   +L QA+  V       +E +  L+ +++++
Sbjct: 321 PVCYLCLEE-GRHAKHEVKPLGAMWKQHKAQLSQALNGVSDKAKEAKEFLVQLKNILQQI 379

Query: 233 RHSAAEEEDAIHALFGSMQDRLAERKALLLQAVQSQYEEKDKAFKEQLSHLATLLPTLQV 292
           + +  + E  + A   ++ D L  +KA LL  V  + E K K   +Q++H    L     
Sbjct: 380 QENGLDYEACLVAQCDALVDALTRQKAKLLTKVTKEREHKLKMVWDQINHCTLKLRQSTG 439

Query: 293 HLVICSSFLSLANKAEFLDLGYELMERLQGIVTRPHHLRPIQSSKIASDHRAEFARCL-- 350
            +  C   +   + + FL +   L++R+Q  V++   ++     K++    AEF   L  
Sbjct: 440 LMEYCLEVIKENDPSGFLQISDALIKRVQ--VSQEQWVKGALEPKVS----AEFDLTLDS 493

Query: 351 EPLL 354
           EPLL
Sbjct: 494 EPLL 497



 Score = 32.3 bits (72), Expect = 1.4
 Identities = 24/82 (29%), Positives = 33/82 (40%), Gaps = 18/82 (21%)

Query: 23  LVCPLCHVQYERPCLLDCFHDFCAGCLRGRATDGRLTCPLCQHQTVLKGPSGLPPVDRLL 82
           L CP+C   +  P +L C H+ C  C R  A               ++ P G      L 
Sbjct: 5   LKCPVCGSLFREPIILPCSHNVCLPCARTIA---------------VQTPDG---EQHLP 46

Query: 83  QFLVDSSGDGVEAVRCANCDLE 104
           Q L+ S G G++A   A   LE
Sbjct: 47  QPLLLSRGSGLQAGAAAAASLE 68


>gi|15208660 tripartite motif protein 21 [Homo sapiens]
          Length = 475

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 57/246 (23%), Positives = 100/246 (40%), Gaps = 15/246 (6%)

Query: 23  LVCPLCHVQYERPCLLDCFHDFCAGCLRGRATDGRLTCPLCQHQTVLKGPSGLPPVDRLL 82
           + CP+C   +  P  ++C H FC  C+      G   CP+C+ + +LK    L P +R L
Sbjct: 14  VTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGSVCPVCRQRFLLK---NLRP-NRQL 69

Query: 83  QFLVDSSGDGVEAVRCANCDLECSEQDVETTYFCNTCGQPLCARCRDETHRARMFARHDI 142
             +V++  +  +  R       C+        FC   G+ LC  C     ++R    H +
Sbjct: 70  ANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCA----QSRKHRDHAM 125

Query: 143 VALGQRSRDVPQKCTLH-AEPYLLFSTDKKLLLCIRCFR-DMQKESRAHCVDLESAYVQG 200
           V L + +++  +K  +   E        +KL + I   R D +K        + + +VQ 
Sbjct: 126 VPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQ 185

Query: 201 CERL-EQAVLAVKALQTATREAIALLQAMVEEVRHSAAEEEDAIHALFGSMQDRLAERKA 259
              L E+    ++ L+   RE + +L     E     A++  A+  L   +  R      
Sbjct: 186 KNFLVEEEQRQLQELEKDEREQLRIL----GEKEAKLAQQSQALQELISELDRRCHSSAL 241

Query: 260 LLLQAV 265
            LLQ V
Sbjct: 242 ELLQEV 247


>gi|149193331 tripartite motif protein 15 [Homo sapiens]
          Length = 465

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 70/289 (24%), Positives = 113/289 (39%), Gaps = 52/289 (17%)

Query: 12  PSSLDAPSIHPL-VCPLCHVQYERPCLLDCFHDFCAGCL-----RGRATDGR-LTCPLCQ 64
           P++     +H L  C LC    E    + C H FC  CL      G  + G+ L CPLCQ
Sbjct: 2   PATPSLKVVHELPACTLCAGPLEDAVTIPCGHTFCRLCLPALSQMGAQSSGKILLCPLCQ 61

Query: 65  HQTVLKGPSGLPPVDRLLQFLVDSSGDGVEAVRCANCDLECSEQDVETTYFCNTCGQPLC 124
            +   + P    P+  L                    +  C E   +  +FC    + LC
Sbjct: 62  EEEQAETPMAPVPLGPL-------------------GETYCEEHGEKIYFFCENDAEFLC 102

Query: 125 ARCRD-ETHRARMFARHDIVALGQRSRDVPQKCTLHAEPYLLFSTDKKLLLCIRCFRDM- 182
             CR+  TH+A     H +  L +  +    +     E     ST++  +  ++C  D  
Sbjct: 103 VFCREGPTHQA-----HTVGFLDEAIQPYRDRLRSRLE---ALSTERDEIEDVKCQEDQK 154

Query: 183 ------QKESRAHCVDLESAYVQGCERLEQAVLAVKALQTA-TREAIALLQAMVEEVRHS 235
                 Q ES+ H   +E+A+    ERL+Q +   + L  A  RE    +    +E    
Sbjct: 155 LQVLLTQIESKKH--QVETAF----ERLQQELEQQRCLLLARLRELEQQIWKERDEYITK 208

Query: 236 AAEEEDAIHALFGSMQDRLAERKALLLQAV---QSQYEEKDKAFKEQLS 281
            +EE   + A    ++++  +  + LLQ V   QS+ E K     E +S
Sbjct: 209 VSEEVTRLGAQVKELEEKCQQPASELLQDVRVNQSRCEMKTFVSPEAIS 257


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.133    0.397 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,333,653
Number of Sequences: 37866
Number of extensions: 1206918
Number of successful extensions: 6424
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 134
Number of HSP's successfully gapped in prelim test: 246
Number of HSP's that attempted gapping in prelim test: 5835
Number of HSP's gapped (non-prelim): 735
length of query: 634
length of database: 18,247,518
effective HSP length: 108
effective length of query: 526
effective length of database: 14,157,990
effective search space: 7447102740
effective search space used: 7447102740
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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