Search of human proteins with 38424083

Search of human proteins with 38424083

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|38424083 short-chain dehydrogenase/reductase 10 isoform d
[Homo sapiens]
         (152 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|38424083 short-chain dehydrogenase/reductase 10 isoform d [Ho...   298   2e-81
gi|38424075 short-chain dehydrogenase/reductase 10 isoform a [Ho...   298   2e-81
gi|38424079 short-chain dehydrogenase/reductase 10 isoform c [Ho...   298   2e-81
gi|38424085 short-chain dehydrogenase/reductase 10 isoform b [Ho...   298   2e-81
gi|38348362 short-chain dehydrogenase/reductase 10 isoform e [Ho...   171   2e-43
gi|38424081 short-chain dehydrogenase/reductase 10 isoform f [Ho...   171   2e-43
gi|32455239 11-beta-hydroxysteroid dehydrogenase 1 [Homo sapiens]     127   5e-30
gi|5031765 11-beta-hydroxysteroid dehydrogenase 1 [Homo sapiens]      127   5e-30
gi|7706318 dehydrogenase/reductase (SDR family) member 7 [Homo s...    49   1e-06
gi|20149619 dehydrogenase/reductase (SDR family) member 7B [Homo...    49   2e-06
gi|44680136 3-hydroxybutyrate dehydrogenase, type 1 precursor [H...    46   1e-05
gi|44680133 3-hydroxybutyrate dehydrogenase, type 1 precursor [H...    46   1e-05
gi|17738292 3-hydroxybutyrate dehydrogenase, type 1 precursor [H...    46   1e-05
gi|150247226 retinol dehydrogenase 16 [Homo sapiens]                   46   1e-05
gi|157739938 dehydrogenase/reductase (SDR family) member 7C [Hom...    46   1e-05
gi|19743808 hydroxysteroid (17-beta) dehydrogenase 6 [Homo sapiens]    46   1e-05
gi|7657478 retinol dehydrogenase 8 (all-trans) [Homo sapiens]          46   1e-05
gi|4504503 hydroxysteroid (17-beta) dehydrogenase 2 [Homo sapiens]     45   2e-05
gi|142976729 estradiol 17-beta-dehydrogenase 11 [Homo sapiens]         43   1e-04
gi|22507405 short chain dehydrogenase/reductase family 9C, membe...    41   4e-04
gi|40548397 NADP-dependent retinol dehydrogenase/reductase [Homo...    40   6e-04
gi|210032112 hydroxysteroid (17-beta) dehydrogenase 13 isoform B...    40   6e-04
gi|210032110 hydroxysteroid (17-beta) dehydrogenase 13 isoform A...    40   6e-04
gi|214010158 NADP-dependent retinol dehydrogenase/reductase [Hom...    40   6e-04
gi|214010156 NADP-dependent retinol dehydrogenase/reductase [Hom...    40   6e-04
gi|22758144 NADP-dependent retinol dehydrogenase/reductase [Homo...    40   6e-04
gi|50726952 retinol dehydrogenase 5 (11-cis and 9-cis) [Homo sap...    40   8e-04
gi|59889578 dehydrogenase/reductase (SDR family) member 10 [Homo...    38   0.004
gi|7705855 hydroxysteroid (17-beta) dehydrogenase 12 [Homo sapiens]    37   0.005
gi|119392083 hydroxysteroid (11-beta) dehydrogenase 2 [Homo sapi...    37   0.008

>gi|38424083 short-chain dehydrogenase/reductase 10 isoform d [Homo
           sapiens]
          Length = 152

 Score =  298 bits (762), Expect = 2e-81
 Identities = 152/152 (100%), Positives = 152/152 (100%)

Query: 1   MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 60
           MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR
Sbjct: 1   MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 60

Query: 61  ELDVQDVNVAITMCVLGLRDRASAAEAVRGVTRVKAAPGPKAALAVIRGGATRAAGVFYP 120
           ELDVQDVNVAITMCVLGLRDRASAAEAVRGVTRVKAAPGPKAALAVIRGGATRAAGVFYP
Sbjct: 61  ELDVQDVNVAITMCVLGLRDRASAAEAVRGVTRVKAAPGPKAALAVIRGGATRAAGVFYP 120

Query: 121 WRFRLLCLLRRWLPRPRAWFIRQELNVTAAAA 152
           WRFRLLCLLRRWLPRPRAWFIRQELNVTAAAA
Sbjct: 121 WRFRLLCLLRRWLPRPRAWFIRQELNVTAAAA 152


>gi|38424075 short-chain dehydrogenase/reductase 10 isoform a [Homo
           sapiens]
          Length = 205

 Score =  298 bits (762), Expect = 2e-81
 Identities = 152/152 (100%), Positives = 152/152 (100%)

Query: 1   MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 60
           MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR
Sbjct: 54  MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 113

Query: 61  ELDVQDVNVAITMCVLGLRDRASAAEAVRGVTRVKAAPGPKAALAVIRGGATRAAGVFYP 120
           ELDVQDVNVAITMCVLGLRDRASAAEAVRGVTRVKAAPGPKAALAVIRGGATRAAGVFYP
Sbjct: 114 ELDVQDVNVAITMCVLGLRDRASAAEAVRGVTRVKAAPGPKAALAVIRGGATRAAGVFYP 173

Query: 121 WRFRLLCLLRRWLPRPRAWFIRQELNVTAAAA 152
           WRFRLLCLLRRWLPRPRAWFIRQELNVTAAAA
Sbjct: 174 WRFRLLCLLRRWLPRPRAWFIRQELNVTAAAA 205


>gi|38424079 short-chain dehydrogenase/reductase 10 isoform c [Homo
           sapiens]
          Length = 199

 Score =  298 bits (762), Expect = 2e-81
 Identities = 152/152 (100%), Positives = 152/152 (100%)

Query: 1   MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 60
           MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR
Sbjct: 48  MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 107

Query: 61  ELDVQDVNVAITMCVLGLRDRASAAEAVRGVTRVKAAPGPKAALAVIRGGATRAAGVFYP 120
           ELDVQDVNVAITMCVLGLRDRASAAEAVRGVTRVKAAPGPKAALAVIRGGATRAAGVFYP
Sbjct: 108 ELDVQDVNVAITMCVLGLRDRASAAEAVRGVTRVKAAPGPKAALAVIRGGATRAAGVFYP 167

Query: 121 WRFRLLCLLRRWLPRPRAWFIRQELNVTAAAA 152
           WRFRLLCLLRRWLPRPRAWFIRQELNVTAAAA
Sbjct: 168 WRFRLLCLLRRWLPRPRAWFIRQELNVTAAAA 199


>gi|38424085 short-chain dehydrogenase/reductase 10 isoform b [Homo
           sapiens]
          Length = 286

 Score =  298 bits (762), Expect = 2e-81
 Identities = 152/152 (100%), Positives = 152/152 (100%)

Query: 1   MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 60
           MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR
Sbjct: 135 MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 194

Query: 61  ELDVQDVNVAITMCVLGLRDRASAAEAVRGVTRVKAAPGPKAALAVIRGGATRAAGVFYP 120
           ELDVQDVNVAITMCVLGLRDRASAAEAVRGVTRVKAAPGPKAALAVIRGGATRAAGVFYP
Sbjct: 195 ELDVQDVNVAITMCVLGLRDRASAAEAVRGVTRVKAAPGPKAALAVIRGGATRAAGVFYP 254

Query: 121 WRFRLLCLLRRWLPRPRAWFIRQELNVTAAAA 152
           WRFRLLCLLRRWLPRPRAWFIRQELNVTAAAA
Sbjct: 255 WRFRLLCLLRRWLPRPRAWFIRQELNVTAAAA 286


>gi|38348362 short-chain dehydrogenase/reductase 10 isoform e [Homo
           sapiens]
          Length = 315

 Score =  171 bits (434), Expect = 2e-43
 Identities = 90/92 (97%), Positives = 90/92 (97%)

Query: 1   MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 60
           MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR
Sbjct: 135 MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 194

Query: 61  ELDVQDVNVAITMCVLGLRDRASAAEAVRGVT 92
           ELDVQDVNVAITMCVLGLRDRASAAEAVR  T
Sbjct: 195 ELDVQDVNVAITMCVLGLRDRASAAEAVRSST 226


>gi|38424081 short-chain dehydrogenase/reductase 10 isoform f
          [Homo sapiens]
          Length = 181

 Score =  171 bits (434), Expect = 2e-43
 Identities = 90/92 (97%), Positives = 90/92 (97%)

Query: 1  MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 60
          MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR
Sbjct: 1  MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 60

Query: 61 ELDVQDVNVAITMCVLGLRDRASAAEAVRGVT 92
          ELDVQDVNVAITMCVLGLRDRASAAEAVR  T
Sbjct: 61 ELDVQDVNVAITMCVLGLRDRASAAEAVRSST 92


>gi|32455239 11-beta-hydroxysteroid dehydrogenase 1 [Homo sapiens]
          Length = 292

 Score =  127 bits (318), Expect = 5e-30
 Identities = 66/119 (55%), Positives = 84/119 (70%)

Query: 1   MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 60
           M+VNF+SYV LT  ALP L  S GS+VVVSSL G+V       YSA+KFALDGFF S+R+
Sbjct: 140 MEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRK 199

Query: 61  ELDVQDVNVAITMCVLGLRDRASAAEAVRGVTRVKAAPGPKAALAVIRGGATRAAGVFY 119
           E  V  VNV+IT+CVLGL D  +A +AV G+  ++AAP  + AL +I+GGA R   V+Y
Sbjct: 200 EYSVSRVNVSITLCVLGLIDTETAMKAVSGIVHMQAAPKEECALEIIKGGALRQEEVYY 258


>gi|5031765 11-beta-hydroxysteroid dehydrogenase 1 [Homo sapiens]
          Length = 292

 Score =  127 bits (318), Expect = 5e-30
 Identities = 66/119 (55%), Positives = 84/119 (70%)

Query: 1   MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 60
           M+VNF+SYV LT  ALP L  S GS+VVVSSL G+V       YSA+KFALDGFF S+R+
Sbjct: 140 MEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRK 199

Query: 61  ELDVQDVNVAITMCVLGLRDRASAAEAVRGVTRVKAAPGPKAALAVIRGGATRAAGVFY 119
           E  V  VNV+IT+CVLGL D  +A +AV G+  ++AAP  + AL +I+GGA R   V+Y
Sbjct: 200 EYSVSRVNVSITLCVLGLIDTETAMKAVSGIVHMQAAPKEECALEIIKGGALRQEEVYY 258


>gi|7706318 dehydrogenase/reductase (SDR family) member 7 [Homo
           sapiens]
          Length = 339

 Score = 49.3 bits (116), Expect = 1e-06
 Identities = 27/75 (36%), Positives = 41/75 (54%), Gaps = 1/75 (1%)

Query: 1   MQVNFVSYVQLTSRALPSLTDSK-GSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLR 59
           +++N++  V LT   LP + + K G +V V+S+LG +    S  Y A+K AL GFF  LR
Sbjct: 159 IELNYLGTVSLTKCVLPHMIERKQGKIVTVNSILGIISVPLSIGYCASKHALRGFFNGLR 218

Query: 60  RELDVQDVNVAITMC 74
            EL      +   +C
Sbjct: 219 TELATYPGIIVSNIC 233


>gi|20149619 dehydrogenase/reductase (SDR family) member 7B [Homo
           sapiens]
          Length = 325

 Score = 48.9 bits (115), Expect = 2e-06
 Identities = 24/72 (33%), Positives = 41/72 (56%), Gaps = 1/72 (1%)

Query: 1   MQVNFVSYVQLTSRALPSLTDSK-GSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLR 59
           M+ N+   V LT   LPS+   + G +V +SS+ G++   F + Y+A+K A   FF  LR
Sbjct: 163 METNYFGPVALTKALLPSMIKRRQGHIVAISSIQGKMSIPFRSAYAASKHATQAFFDCLR 222

Query: 60  RELDVQDVNVAI 71
            E++  ++ V +
Sbjct: 223 AEMEQYEIEVTV 234


>gi|44680136 3-hydroxybutyrate dehydrogenase, type 1 precursor [Homo
           sapiens]
          Length = 343

 Score = 46.2 bits (108), Expect = 1e-05
 Identities = 24/70 (34%), Positives = 39/70 (55%)

Query: 2   QVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRE 61
           +VN    V++T   LP +  +KG +V +SS+LGR+     +PY   KF ++ F   LR E
Sbjct: 166 EVNLWGTVRMTKSFLPLIRRAKGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYE 225

Query: 62  LDVQDVNVAI 71
           +    V V++
Sbjct: 226 MYPLGVKVSV 235


>gi|44680133 3-hydroxybutyrate dehydrogenase, type 1 precursor [Homo
           sapiens]
          Length = 343

 Score = 46.2 bits (108), Expect = 1e-05
 Identities = 24/70 (34%), Positives = 39/70 (55%)

Query: 2   QVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRE 61
           +VN    V++T   LP +  +KG +V +SS+LGR+     +PY   KF ++ F   LR E
Sbjct: 166 EVNLWGTVRMTKSFLPLIRRAKGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYE 225

Query: 62  LDVQDVNVAI 71
           +    V V++
Sbjct: 226 MYPLGVKVSV 235


>gi|17738292 3-hydroxybutyrate dehydrogenase, type 1 precursor [Homo
           sapiens]
          Length = 343

 Score = 46.2 bits (108), Expect = 1e-05
 Identities = 24/70 (34%), Positives = 39/70 (55%)

Query: 2   QVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRE 61
           +VN    V++T   LP +  +KG +V +SS+LGR+     +PY   KF ++ F   LR E
Sbjct: 166 EVNLWGTVRMTKSFLPLIRRAKGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYE 225

Query: 62  LDVQDVNVAI 71
           +    V V++
Sbjct: 226 MYPLGVKVSV 235


>gi|150247226 retinol dehydrogenase 16 [Homo sapiens]
          Length = 317

 Score = 46.2 bits (108), Expect = 1e-05
 Identities = 26/71 (36%), Positives = 42/71 (59%), Gaps = 1/71 (1%)

Query: 1   MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 60
           + VN +  + +T   LP +  ++G +V VSS++GRV + F   Y  +K+ ++ F  SLRR
Sbjct: 134 LDVNLLGVIDVTLSLLPLVRRARGRVVNVSSVMGRV-SLFGGGYCISKYGVEAFSDSLRR 192

Query: 61  ELDVQDVNVAI 71
           EL    V VA+
Sbjct: 193 ELSYFGVKVAM 203


>gi|157739938 dehydrogenase/reductase (SDR family) member 7C [Homo
           sapiens]
          Length = 311

 Score = 46.2 bits (108), Expect = 1e-05
 Identities = 24/71 (33%), Positives = 41/71 (57%), Gaps = 1/71 (1%)

Query: 1   MQVNFVSYVQLTSRALPSLTDSK-GSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLR 59
           M  N+   + LT   LP++   + G +V+V+++ G+    F T Y+A+K A  GFF  LR
Sbjct: 147 MDANYFGPITLTKALLPNMISRRTGQIVLVNNIQGKFGIPFRTTYAASKHAALGFFDCLR 206

Query: 60  RELDVQDVNVA 70
            E++  DV ++
Sbjct: 207 AEVEEYDVVIS 217


>gi|19743808 hydroxysteroid (17-beta) dehydrogenase 6 [Homo sapiens]
          Length = 317

 Score = 45.8 bits (107), Expect = 1e-05
 Identities = 25/71 (35%), Positives = 42/71 (59%), Gaps = 1/71 (1%)

Query: 1   MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 60
           ++VN +  +Q+T   LP +  ++G +V VSS+LGRV   F   Y  +K+ ++ F   LRR
Sbjct: 134 LKVNLIGVIQVTLSMLPLVRRARGRIVNVSSILGRV-AFFVGGYCVSKYGVEAFSDILRR 192

Query: 61  ELDVQDVNVAI 71
           E+    V ++I
Sbjct: 193 EIQHFGVKISI 203


>gi|7657478 retinol dehydrogenase 8 (all-trans) [Homo sapiens]
          Length = 311

 Score = 45.8 bits (107), Expect = 1e-05
 Identities = 25/60 (41%), Positives = 37/60 (61%), Gaps = 1/60 (1%)

Query: 4   NFVSYVQLTSRALPSLTDSK-GSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRREL 62
           NF   V+L    LP +   + G +VV+SS++G     F+  Y+A+KFAL+GFF SL  +L
Sbjct: 114 NFFGAVRLVKAVLPGMKRRRQGHIVVISSVMGLQGVIFNDVYAASKFALEGFFESLAIQL 173


>gi|4504503 hydroxysteroid (17-beta) dehydrogenase 2 [Homo sapiens]
          Length = 387

 Score = 45.1 bits (105), Expect = 2e-05
 Identities = 28/70 (40%), Positives = 36/70 (51%)

Query: 1   MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 60
           M VNF   V++T   LP L  SKG LV VSS+ G  P      Y ++K A+  F   +R 
Sbjct: 189 MAVNFFGTVEVTKTFLPLLRKSKGRLVNVSSMGGGAPMERLASYGSSKAAVTMFSSVMRL 248

Query: 61  ELDVQDVNVA 70
           EL    + VA
Sbjct: 249 ELSKWGIKVA 258


>gi|142976729 estradiol 17-beta-dehydrogenase 11 [Homo sapiens]
          Length = 300

 Score = 42.7 bits (99), Expect = 1e-04
 Identities = 37/148 (25%), Positives = 65/148 (43%), Gaps = 4/148 (2%)

Query: 2   QVNFVSYVQLTSRALPSLT-DSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 60
           +VN +++   T   LP++T ++ G +V V+S  G V   F   Y ++KFA  GF  +L  
Sbjct: 142 EVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTD 201

Query: 61  ELDVQDVNVAITMCVLGLRDRASAAEAVRGVTRVKAAPGPKAAL-AVIRGGATRAAGVFY 119
           EL    +    T C+    +  +        T +     P+  +  ++ G  T    +F 
Sbjct: 202 ELAALQITGVKTTCL--CPNFVNTGFIKNPSTSLGPTLEPEEVVNRLMHGILTEQKMIFI 259

Query: 120 PWRFRLLCLLRRWLPRPRAWFIRQELNV 147
           P     L  L R LP      ++Q+++V
Sbjct: 260 PSSIAFLTTLERILPERFLAVLKQKISV 287


>gi|22507405 short chain dehydrogenase/reductase family 9C, member 7
           [Homo sapiens]
          Length = 313

 Score = 40.8 bits (94), Expect = 4e-04
 Identities = 25/71 (35%), Positives = 38/71 (53%), Gaps = 1/71 (1%)

Query: 1   MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 60
           + VN V  +++T   LP +  ++G +V +SS  GRV       Y  +KF ++ F  S+RR
Sbjct: 130 INVNLVGLIEVTLHMLPMVKRARGRVVNMSSSGGRVAV-IGGGYCVSKFGVEAFSDSIRR 188

Query: 61  ELDVQDVNVAI 71
           EL    V V I
Sbjct: 189 ELYYFGVKVCI 199


>gi|40548397 NADP-dependent retinol dehydrogenase/reductase [Homo
           sapiens]
          Length = 319

 Score = 40.4 bits (93), Expect = 6e-04
 Identities = 22/70 (31%), Positives = 42/70 (60%), Gaps = 1/70 (1%)

Query: 1   MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 60
           ++VN    + +T   LP +  ++G ++ VSS+ GR+       Y+ +K+A++GF  SLRR
Sbjct: 134 IEVNLFGLISVTLNMLPLVKKAQGRVINVSSVGGRLAI-VGGGYTPSKYAVEGFNDSLRR 192

Query: 61  ELDVQDVNVA 70
           ++    V+V+
Sbjct: 193 DMKAFGVHVS 202


>gi|210032112 hydroxysteroid (17-beta) dehydrogenase 13 isoform B
           [Homo sapiens]
          Length = 264

 Score = 40.4 bits (93), Expect = 6e-04
 Identities = 34/148 (22%), Positives = 63/148 (42%), Gaps = 4/148 (2%)

Query: 2   QVNFVSYVQLTSRALPSLTD-SKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 60
           +VN + +  +T   LPS+ + + G +V V+S+ G     +  PY ++KFA  GF   L  
Sbjct: 106 EVNILGHFWITKALLPSMMERNHGHIVTVASVCGHEGIPYLIPYCSSKFAAVGFHRGLTS 165

Query: 61  ELDVQDVNVAITMCVLGLRDRASAAEAVRGVTRV-KAAPGPKAALAVIRGGATRAAGVFY 119
           EL         T C+  +    +        TR+       +   ++I G  T    +F 
Sbjct: 166 ELQALGKTGIKTSCLCPV--FVNTGFTKNPSTRLWPVLETDEVVRSLIDGILTNKKMIFV 223

Query: 120 PWRFRLLCLLRRWLPRPRAWFIRQELNV 147
           P    +   L+++LP   +  + +  N+
Sbjct: 224 PSYINIFLRLQKFLPERASAILNRMQNI 251


>gi|210032110 hydroxysteroid (17-beta) dehydrogenase 13 isoform A
           [Homo sapiens]
          Length = 300

 Score = 40.4 bits (93), Expect = 6e-04
 Identities = 34/148 (22%), Positives = 63/148 (42%), Gaps = 4/148 (2%)

Query: 2   QVNFVSYVQLTSRALPSLTD-SKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 60
           +VN + +  +T   LPS+ + + G +V V+S+ G     +  PY ++KFA  GF   L  
Sbjct: 142 EVNILGHFWITKALLPSMMERNHGHIVTVASVCGHEGIPYLIPYCSSKFAAVGFHRGLTS 201

Query: 61  ELDVQDVNVAITMCVLGLRDRASAAEAVRGVTRV-KAAPGPKAALAVIRGGATRAAGVFY 119
           EL         T C+  +    +        TR+       +   ++I G  T    +F 
Sbjct: 202 ELQALGKTGIKTSCLCPV--FVNTGFTKNPSTRLWPVLETDEVVRSLIDGILTNKKMIFV 259

Query: 120 PWRFRLLCLLRRWLPRPRAWFIRQELNV 147
           P    +   L+++LP   +  + +  N+
Sbjct: 260 PSYINIFLRLQKFLPERASAILNRMQNI 287


>gi|214010158 NADP-dependent retinol dehydrogenase/reductase [Homo
           sapiens]
          Length = 319

 Score = 40.4 bits (93), Expect = 6e-04
 Identities = 22/70 (31%), Positives = 42/70 (60%), Gaps = 1/70 (1%)

Query: 1   MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 60
           ++VN    + +T   LP +  ++G ++ VSS+ GR+       Y+ +K+A++GF  SLRR
Sbjct: 134 IEVNLFGLISVTLNMLPLVKKAQGRVINVSSVGGRLAI-VGGGYTPSKYAVEGFNDSLRR 192

Query: 61  ELDVQDVNVA 70
           ++    V+V+
Sbjct: 193 DMKAFGVHVS 202


>gi|214010156 NADP-dependent retinol dehydrogenase/reductase [Homo
           sapiens]
          Length = 319

 Score = 40.4 bits (93), Expect = 6e-04
 Identities = 22/70 (31%), Positives = 42/70 (60%), Gaps = 1/70 (1%)

Query: 1   MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 60
           ++VN    + +T   LP +  ++G ++ VSS+ GR+       Y+ +K+A++GF  SLRR
Sbjct: 134 IEVNLFGLISVTLNMLPLVKKAQGRVINVSSVGGRLAI-VGGGYTPSKYAVEGFNDSLRR 192

Query: 61  ELDVQDVNVA 70
           ++    V+V+
Sbjct: 193 DMKAFGVHVS 202


>gi|22758144 NADP-dependent retinol dehydrogenase/reductase [Homo
           sapiens]
          Length = 319

 Score = 40.4 bits (93), Expect = 6e-04
 Identities = 22/70 (31%), Positives = 42/70 (60%), Gaps = 1/70 (1%)

Query: 1   MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 60
           ++VN    + +T   LP +  ++G ++ VSS+ GR+       Y+ +K+A++GF  SLRR
Sbjct: 134 IEVNLFGLISVTLNMLPLVKKAQGRVINVSSVGGRLAI-VGGGYTPSKYAVEGFNDSLRR 192

Query: 61  ELDVQDVNVA 70
           ++    V+V+
Sbjct: 193 DMKAFGVHVS 202


>gi|50726952 retinol dehydrogenase 5 (11-cis and 9-cis) [Homo
           sapiens]
          Length = 318

 Score = 40.0 bits (92), Expect = 8e-04
 Identities = 22/71 (30%), Positives = 41/71 (57%), Gaps = 1/71 (1%)

Query: 1   MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 60
           + VN +  + +T   LP L  ++G ++ ++S+LGR+  +    Y  +KF L+ F  SLRR
Sbjct: 133 LNVNTMGPIGVTLALLPLLQQARGRVINITSVLGRLAAN-GGGYCVSKFGLEAFSDSLRR 191

Query: 61  ELDVQDVNVAI 71
           ++    + V+I
Sbjct: 192 DVAHFGIRVSI 202


>gi|59889578 dehydrogenase/reductase (SDR family) member 10 [Homo
           sapiens]
          Length = 270

 Score = 37.7 bits (86), Expect = 0.004
 Identities = 18/51 (35%), Positives = 32/51 (62%)

Query: 1   MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFAL 51
           +++N +    LT  ALP L  S+G+++ +SSL+G +  + + PY A K A+
Sbjct: 111 LELNLLGTYTLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAV 161


>gi|7705855 hydroxysteroid (17-beta) dehydrogenase 12 [Homo sapiens]
          Length = 312

 Score = 37.4 bits (85), Expect = 0.005
 Identities = 21/62 (33%), Positives = 34/62 (54%), Gaps = 1/62 (1%)

Query: 1   MQVNFVSYVQLTSRALPSLTD-SKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLR 59
           + +N +S  ++T   LP + + SKG+++ +SS  G +P    T YSA K  +D F   L 
Sbjct: 158 ININILSVCKMTQLVLPGMVERSKGAILNISSGSGMLPVPLLTIYSATKTFVDFFSQCLH 217

Query: 60  RE 61
            E
Sbjct: 218 EE 219


>gi|119392083 hydroxysteroid (11-beta) dehydrogenase 2 [Homo
           sapiens]
          Length = 405

 Score = 36.6 bits (83), Expect = 0.008
 Identities = 24/71 (33%), Positives = 34/71 (47%)

Query: 1   MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 60
           M+VNF   ++LT   LP L  S+G +V V S  G +P      Y  +K A+     +   
Sbjct: 189 MEVNFFGALELTKGLLPLLRSSRGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSC 248

Query: 61  ELDVQDVNVAI 71
           EL    V V+I
Sbjct: 249 ELLPWGVKVSI 259


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.136    0.407 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,136,352
Number of Sequences: 37866
Number of extensions: 190328
Number of successful extensions: 766
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 37
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 721
Number of HSP's gapped (non-prelim): 52
length of query: 152
length of database: 18,247,518
effective HSP length: 93
effective length of query: 59
effective length of database: 14,725,980
effective search space: 868832820
effective search space used: 868832820
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 57 (26.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.