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Search of human proteins with 38424075
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|38424075 short-chain dehydrogenase/reductase 10 isoform a
[Homo sapiens]
(205 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|38424075 short-chain dehydrogenase/reductase 10 isoform a [Ho... 409 e-115
gi|38424079 short-chain dehydrogenase/reductase 10 isoform c [Ho... 358 2e-99
gi|38424085 short-chain dehydrogenase/reductase 10 isoform b [Ho... 358 2e-99
gi|38424083 short-chain dehydrogenase/reductase 10 isoform d [Ho... 298 3e-81
gi|38348362 short-chain dehydrogenase/reductase 10 isoform e [Ho... 231 2e-61
gi|38424081 short-chain dehydrogenase/reductase 10 isoform f [Ho... 171 3e-43
gi|32455239 11-beta-hydroxysteroid dehydrogenase 1 [Homo sapiens] 139 1e-33
gi|5031765 11-beta-hydroxysteroid dehydrogenase 1 [Homo sapiens] 139 1e-33
gi|7706318 dehydrogenase/reductase (SDR family) member 7 [Homo s... 52 4e-07
gi|20149619 dehydrogenase/reductase (SDR family) member 7B [Homo... 50 1e-06
gi|7657478 retinol dehydrogenase 8 (all-trans) [Homo sapiens] 50 1e-06
gi|157739938 dehydrogenase/reductase (SDR family) member 7C [Hom... 48 5e-06
gi|150247226 retinol dehydrogenase 16 [Homo sapiens] 47 1e-05
gi|44680136 3-hydroxybutyrate dehydrogenase, type 1 precursor [H... 47 1e-05
gi|44680133 3-hydroxybutyrate dehydrogenase, type 1 precursor [H... 47 1e-05
gi|17738292 3-hydroxybutyrate dehydrogenase, type 1 precursor [H... 47 1e-05
gi|19743808 hydroxysteroid (17-beta) dehydrogenase 6 [Homo sapiens] 47 1e-05
gi|59889578 dehydrogenase/reductase (SDR family) member 10 [Homo... 46 3e-05
gi|4504503 hydroxysteroid (17-beta) dehydrogenase 2 [Homo sapiens] 45 3e-05
gi|142976729 estradiol 17-beta-dehydrogenase 11 [Homo sapiens] 43 2e-04
gi|210032112 hydroxysteroid (17-beta) dehydrogenase 13 isoform B... 43 2e-04
gi|210032110 hydroxysteroid (17-beta) dehydrogenase 13 isoform A... 43 2e-04
gi|22507405 short chain dehydrogenase/reductase family 9C, membe... 42 4e-04
gi|50726952 retinol dehydrogenase 5 (11-cis and 9-cis) [Homo sap... 41 8e-04
gi|40548397 NADP-dependent retinol dehydrogenase/reductase [Homo... 40 0.001
gi|214010158 NADP-dependent retinol dehydrogenase/reductase [Hom... 40 0.001
gi|214010156 NADP-dependent retinol dehydrogenase/reductase [Hom... 40 0.001
gi|22758144 NADP-dependent retinol dehydrogenase/reductase [Homo... 40 0.001
gi|119392083 hydroxysteroid (11-beta) dehydrogenase 2 [Homo sapi... 39 0.002
gi|223718074 hydroxysteroid (17-beta) dehydrogenase 1 [Homo sapi... 39 0.003
>gi|38424075 short-chain dehydrogenase/reductase 10 isoform a [Homo
sapiens]
Length = 205
Score = 409 bits (1051), Expect = e-115
Identities = 205/205 (100%), Positives = 205/205 (100%)
Query: 1 MKVLLLTGLGALFFAYYWDDNFDPGGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVS 60
MKVLLLTGLGALFFAYYWDDNFDPGGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVS
Sbjct: 1 MKVLLLTGLGALFFAYYWDDNFDPGGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVS 60
Query: 61 YVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDV 120
YVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDV
Sbjct: 61 YVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDV 120
Query: 121 NVAITMCVLGLRDRASAAEAVRGVTRVKAAPGPKAALAVIRGGATRAAGVFYPWRFRLLC 180
NVAITMCVLGLRDRASAAEAVRGVTRVKAAPGPKAALAVIRGGATRAAGVFYPWRFRLLC
Sbjct: 121 NVAITMCVLGLRDRASAAEAVRGVTRVKAAPGPKAALAVIRGGATRAAGVFYPWRFRLLC 180
Query: 181 LLRRWLPRPRAWFIRQELNVTAAAA 205
LLRRWLPRPRAWFIRQELNVTAAAA
Sbjct: 181 LLRRWLPRPRAWFIRQELNVTAAAA 205
>gi|38424079 short-chain dehydrogenase/reductase 10 isoform c [Homo
sapiens]
Length = 199
Score = 358 bits (918), Expect = 2e-99
Identities = 181/181 (100%), Positives = 181/181 (100%)
Query: 25 GGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSS 84
GGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSS
Sbjct: 19 GGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSS 78
Query: 85 LLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVRGV 144
LLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVRGV
Sbjct: 79 LLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVRGV 138
Query: 145 TRVKAAPGPKAALAVIRGGATRAAGVFYPWRFRLLCLLRRWLPRPRAWFIRQELNVTAAA 204
TRVKAAPGPKAALAVIRGGATRAAGVFYPWRFRLLCLLRRWLPRPRAWFIRQELNVTAAA
Sbjct: 139 TRVKAAPGPKAALAVIRGGATRAAGVFYPWRFRLLCLLRRWLPRPRAWFIRQELNVTAAA 198
Query: 205 A 205
A
Sbjct: 199 A 199
>gi|38424085 short-chain dehydrogenase/reductase 10 isoform b [Homo
sapiens]
Length = 286
Score = 358 bits (918), Expect = 2e-99
Identities = 181/181 (100%), Positives = 181/181 (100%)
Query: 25 GGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSS 84
GGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSS
Sbjct: 106 GGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSS 165
Query: 85 LLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVRGV 144
LLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVRGV
Sbjct: 166 LLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVRGV 225
Query: 145 TRVKAAPGPKAALAVIRGGATRAAGVFYPWRFRLLCLLRRWLPRPRAWFIRQELNVTAAA 204
TRVKAAPGPKAALAVIRGGATRAAGVFYPWRFRLLCLLRRWLPRPRAWFIRQELNVTAAA
Sbjct: 226 TRVKAAPGPKAALAVIRGGATRAAGVFYPWRFRLLCLLRRWLPRPRAWFIRQELNVTAAA 285
Query: 205 A 205
A
Sbjct: 286 A 286
Score = 57.4 bits (137), Expect = 8e-09
Identities = 25/27 (92%), Positives = 25/27 (92%)
Query: 1 MKVLLLTGLGALFFAYYWDDNFDPGGL 27
MKVLLLTGLGALFFAYYWDDNFDP L
Sbjct: 1 MKVLLLTGLGALFFAYYWDDNFDPASL 27
>gi|38424083 short-chain dehydrogenase/reductase 10 isoform d [Homo
sapiens]
Length = 152
Score = 298 bits (762), Expect = 3e-81
Identities = 152/152 (100%), Positives = 152/152 (100%)
Query: 54 MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 113
MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR
Sbjct: 1 MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 60
Query: 114 ELDVQDVNVAITMCVLGLRDRASAAEAVRGVTRVKAAPGPKAALAVIRGGATRAAGVFYP 173
ELDVQDVNVAITMCVLGLRDRASAAEAVRGVTRVKAAPGPKAALAVIRGGATRAAGVFYP
Sbjct: 61 ELDVQDVNVAITMCVLGLRDRASAAEAVRGVTRVKAAPGPKAALAVIRGGATRAAGVFYP 120
Query: 174 WRFRLLCLLRRWLPRPRAWFIRQELNVTAAAA 205
WRFRLLCLLRRWLPRPRAWFIRQELNVTAAAA
Sbjct: 121 WRFRLLCLLRRWLPRPRAWFIRQELNVTAAAA 152
>gi|38348362 short-chain dehydrogenase/reductase 10 isoform e [Homo
sapiens]
Length = 315
Score = 231 bits (590), Expect = 2e-61
Identities = 119/121 (98%), Positives = 119/121 (98%)
Query: 25 GGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSS 84
GGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSS
Sbjct: 106 GGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSS 165
Query: 85 LLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVRGV 144
LLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVR
Sbjct: 166 LLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVRSS 225
Query: 145 T 145
T
Sbjct: 226 T 226
Score = 57.4 bits (137), Expect = 8e-09
Identities = 25/27 (92%), Positives = 25/27 (92%)
Query: 1 MKVLLLTGLGALFFAYYWDDNFDPGGL 27
MKVLLLTGLGALFFAYYWDDNFDP L
Sbjct: 1 MKVLLLTGLGALFFAYYWDDNFDPASL 27
>gi|38424081 short-chain dehydrogenase/reductase 10 isoform f [Homo
sapiens]
Length = 181
Score = 171 bits (434), Expect = 3e-43
Identities = 90/92 (97%), Positives = 90/92 (97%)
Query: 54 MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 113
MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR
Sbjct: 1 MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 60
Query: 114 ELDVQDVNVAITMCVLGLRDRASAAEAVRGVT 145
ELDVQDVNVAITMCVLGLRDRASAAEAVR T
Sbjct: 61 ELDVQDVNVAITMCVLGLRDRASAAEAVRSST 92
>gi|32455239 11-beta-hydroxysteroid dehydrogenase 1 [Homo sapiens]
Length = 292
Score = 139 bits (351), Expect = 1e-33
Identities = 76/148 (51%), Positives = 95/148 (64%)
Query: 25 GGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSS 84
GGLD L+LNHI R M+VNF+SYV LT ALP L S GS+VVVSS
Sbjct: 111 GGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSS 170
Query: 85 LLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVRGV 144
L G+V YSA+KFALDGFF S+R+E V VNV+IT+CVLGL D +A +AV G+
Sbjct: 171 LAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGI 230
Query: 145 TRVKAAPGPKAALAVIRGGATRAAGVFY 172
++AAP + AL +I+GGA R V+Y
Sbjct: 231 VHMQAAPKEECALEIIKGGALRQEEVYY 258
>gi|5031765 11-beta-hydroxysteroid dehydrogenase 1 [Homo sapiens]
Length = 292
Score = 139 bits (351), Expect = 1e-33
Identities = 76/148 (51%), Positives = 95/148 (64%)
Query: 25 GGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSS 84
GGLD L+LNHI R M+VNF+SYV LT ALP L S GS+VVVSS
Sbjct: 111 GGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSS 170
Query: 85 LLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVRGV 144
L G+V YSA+KFALDGFF S+R+E V VNV+IT+CVLGL D +A +AV G+
Sbjct: 171 LAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGI 230
Query: 145 TRVKAAPGPKAALAVIRGGATRAAGVFY 172
++AAP + AL +I+GGA R V+Y
Sbjct: 231 VHMQAAPKEECALEIIKGGALRQEEVYY 258
>gi|7706318 dehydrogenase/reductase (SDR family) member 7 [Homo
sapiens]
Length = 339
Score = 52.0 bits (123), Expect = 4e-07
Identities = 35/104 (33%), Positives = 51/104 (49%), Gaps = 1/104 (0%)
Query: 25 GGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSK-GSLVVVS 83
G +D LV N + S R L+++N++ V LT LP + + K G +V V+
Sbjct: 130 GRIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVLPHMIERKQGKIVTVN 189
Query: 84 SLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITMC 127
S+LG + S Y A+K AL GFF LR EL + +C
Sbjct: 190 SILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGIIVSNIC 233
>gi|20149619 dehydrogenase/reductase (SDR family) member 7B [Homo
sapiens]
Length = 325
Score = 50.1 bits (118), Expect = 1e-06
Identities = 32/102 (31%), Positives = 55/102 (53%), Gaps = 3/102 (2%)
Query: 25 GGLDYLVLNHIGGAPAGT-RARSPQATRWLMQVNFVSYVQLTSRALPSLTDSK-GSLVVV 82
G +D LV N+ G + GT + + +M+ N+ V LT LPS+ + G +V +
Sbjct: 134 GYVDILV-NNAGISYRGTIMDTTVDVDKRVMETNYFGPVALTKALLPSMIKRRQGHIVAI 192
Query: 83 SSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAI 124
SS+ G++ F + Y+A+K A FF LR E++ ++ V +
Sbjct: 193 SSIQGKMSIPFRSAYAASKHATQAFFDCLRAEMEQYEIEVTV 234
>gi|7657478 retinol dehydrogenase 8 (all-trans) [Homo sapiens]
Length = 311
Score = 50.1 bits (118), Expect = 1e-06
Identities = 33/92 (35%), Positives = 48/92 (52%), Gaps = 1/92 (1%)
Query: 25 GGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSK-GSLVVVS 83
G +D LV N G S A + + NF V+L LP + + G +VV+S
Sbjct: 82 GEVDVLVNNAGMGLVGPLEGLSLAAMQNVFDTNFFGAVRLVKAVLPGMKRRRQGHIVVIS 141
Query: 84 SLLGRVPTSFSTPYSAAKFALDGFFGSLRREL 115
S++G F+ Y+A+KFAL+GFF SL +L
Sbjct: 142 SVMGLQGVIFNDVYAASKFALEGFFESLAIQL 173
>gi|157739938 dehydrogenase/reductase (SDR family) member 7C [Homo
sapiens]
Length = 311
Score = 48.1 bits (113), Expect = 5e-06
Identities = 29/100 (29%), Positives = 51/100 (51%), Gaps = 1/100 (1%)
Query: 25 GGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSK-GSLVVVS 83
G +D L+ N S + + +M N+ + LT LP++ + G +V+V+
Sbjct: 118 GCVDILINNASVKVKGPAHKISLELDKKIMDANYFGPITLTKALLPNMISRRTGQIVLVN 177
Query: 84 SLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVA 123
++ G+ F T Y+A+K A GFF LR E++ DV ++
Sbjct: 178 NIQGKFGIPFRTTYAASKHAALGFFDCLRAEVEEYDVVIS 217
>gi|150247226 retinol dehydrogenase 16 [Homo sapiens]
Length = 317
Score = 47.0 bits (110), Expect = 1e-05
Identities = 26/72 (36%), Positives = 43/72 (59%), Gaps = 1/72 (1%)
Query: 53 LMQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLR 112
++ VN + + +T LP + ++G +V VSS++GRV + F Y +K+ ++ F SLR
Sbjct: 133 ILDVNLLGVIDVTLSLLPLVRRARGRVVNVSSVMGRV-SLFGGGYCISKYGVEAFSDSLR 191
Query: 113 RELDVQDVNVAI 124
REL V VA+
Sbjct: 192 RELSYFGVKVAM 203
>gi|44680136 3-hydroxybutyrate dehydrogenase, type 1 precursor [Homo
sapiens]
Length = 343
Score = 46.6 bits (109), Expect = 1e-05
Identities = 25/79 (31%), Positives = 43/79 (54%)
Query: 46 SPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALD 105
S + + + +VN V++T LP + +KG +V +SS+LGR+ +PY KF ++
Sbjct: 157 SLETYKQVAEVNLWGTVRMTKSFLPLIRRAKGRVVNISSMLGRMANPARSPYCITKFGVE 216
Query: 106 GFFGSLRRELDVQDVNVAI 124
F LR E+ V V++
Sbjct: 217 AFSDCLRYEMYPLGVKVSV 235
>gi|44680133 3-hydroxybutyrate dehydrogenase, type 1 precursor [Homo
sapiens]
Length = 343
Score = 46.6 bits (109), Expect = 1e-05
Identities = 25/79 (31%), Positives = 43/79 (54%)
Query: 46 SPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALD 105
S + + + +VN V++T LP + +KG +V +SS+LGR+ +PY KF ++
Sbjct: 157 SLETYKQVAEVNLWGTVRMTKSFLPLIRRAKGRVVNISSMLGRMANPARSPYCITKFGVE 216
Query: 106 GFFGSLRRELDVQDVNVAI 124
F LR E+ V V++
Sbjct: 217 AFSDCLRYEMYPLGVKVSV 235
>gi|17738292 3-hydroxybutyrate dehydrogenase, type 1 precursor [Homo
sapiens]
Length = 343
Score = 46.6 bits (109), Expect = 1e-05
Identities = 25/79 (31%), Positives = 43/79 (54%)
Query: 46 SPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALD 105
S + + + +VN V++T LP + +KG +V +SS+LGR+ +PY KF ++
Sbjct: 157 SLETYKQVAEVNLWGTVRMTKSFLPLIRRAKGRVVNISSMLGRMANPARSPYCITKFGVE 216
Query: 106 GFFGSLRRELDVQDVNVAI 124
F LR E+ V V++
Sbjct: 217 AFSDCLRYEMYPLGVKVSV 235
>gi|19743808 hydroxysteroid (17-beta) dehydrogenase 6 [Homo sapiens]
Length = 317
Score = 46.6 bits (109), Expect = 1e-05
Identities = 25/72 (34%), Positives = 43/72 (59%), Gaps = 1/72 (1%)
Query: 53 LMQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLR 112
+++VN + +Q+T LP + ++G +V VSS+LGRV F Y +K+ ++ F LR
Sbjct: 133 MLKVNLIGVIQVTLSMLPLVRRARGRIVNVSSILGRV-AFFVGGYCVSKYGVEAFSDILR 191
Query: 113 RELDVQDVNVAI 124
RE+ V ++I
Sbjct: 192 REIQHFGVKISI 203
>gi|59889578 dehydrogenase/reductase (SDR family) member 10 [Homo
sapiens]
Length = 270
Score = 45.8 bits (107), Expect = 3e-05
Identities = 30/82 (36%), Positives = 46/82 (56%), Gaps = 3/82 (3%)
Query: 25 GGLDYLVLNHIGGAPAGTRAR--SPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVV 82
G LD V+N+ G P R S Q R L+++N + LT ALP L S+G+++ +
Sbjct: 81 GRLD-CVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALPYLRKSQGNVINI 139
Query: 83 SSLLGRVPTSFSTPYSAAKFAL 104
SSL+G + + + PY A K A+
Sbjct: 140 SSLVGAIGQAQAVPYVATKGAV 161
>gi|4504503 hydroxysteroid (17-beta) dehydrogenase 2 [Homo sapiens]
Length = 387
Score = 45.4 bits (106), Expect = 3e-05
Identities = 33/97 (34%), Positives = 45/97 (46%), Gaps = 2/97 (2%)
Query: 29 YLVLNHIG--GAPAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLL 86
+ V+N+ G G P + M VNF V++T LP L SKG LV VSS+
Sbjct: 162 WAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTVEVTKTFLPLLRKSKGRLVNVSSMG 221
Query: 87 GRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVA 123
G P Y ++K A+ F +R EL + VA
Sbjct: 222 GGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKVA 258
>gi|142976729 estradiol 17-beta-dehydrogenase 11 [Homo sapiens]
Length = 300
Score = 42.7 bits (99), Expect = 2e-04
Identities = 37/148 (25%), Positives = 65/148 (43%), Gaps = 4/148 (2%)
Query: 55 QVNFVSYVQLTSRALPSLT-DSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 113
+VN +++ T LP++T ++ G +V V+S G V F Y ++KFA GF +L
Sbjct: 142 EVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTD 201
Query: 114 ELDVQDVNVAITMCVLGLRDRASAAEAVRGVTRVKAAPGPKAAL-AVIRGGATRAAGVFY 172
EL + T C+ + + T + P+ + ++ G T +F
Sbjct: 202 ELAALQITGVKTTCL--CPNFVNTGFIKNPSTSLGPTLEPEEVVNRLMHGILTEQKMIFI 259
Query: 173 PWRFRLLCLLRRWLPRPRAWFIRQELNV 200
P L L R LP ++Q+++V
Sbjct: 260 PSSIAFLTTLERILPERFLAVLKQKISV 287
>gi|210032112 hydroxysteroid (17-beta) dehydrogenase 13 isoform B
[Homo sapiens]
Length = 264
Score = 42.7 bits (99), Expect = 2e-04
Identities = 39/174 (22%), Positives = 73/174 (41%), Gaps = 5/174 (2%)
Query: 30 LVLNHIGGA-PAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTD-SKGSLVVVSSLLG 87
+V+N+ G PA + + +VN + + +T LPS+ + + G +V V+S+ G
Sbjct: 80 IVVNNAGTVYPADLLSTKDEEITKTFEVNILGHFWITKALLPSMMERNHGHIVTVASVCG 139
Query: 88 RVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVRGVTRV 147
+ PY ++KFA GF L EL T C+ + + TR+
Sbjct: 140 HEGIPYLIPYCSSKFAAVGFHRGLTSELQALGKTGIKTSCLCPV--FVNTGFTKNPSTRL 197
Query: 148 -KAAPGPKAALAVIRGGATRAAGVFYPWRFRLLCLLRRWLPRPRAWFIRQELNV 200
+ ++I G T +F P + L+++LP + + + N+
Sbjct: 198 WPVLETDEVVRSLIDGILTNKKMIFVPSYINIFLRLQKFLPERASAILNRMQNI 251
>gi|210032110 hydroxysteroid (17-beta) dehydrogenase 13 isoform A
[Homo sapiens]
Length = 300
Score = 42.7 bits (99), Expect = 2e-04
Identities = 39/174 (22%), Positives = 73/174 (41%), Gaps = 5/174 (2%)
Query: 30 LVLNHIGGA-PAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTD-SKGSLVVVSSLLG 87
+V+N+ G PA + + +VN + + +T LPS+ + + G +V V+S+ G
Sbjct: 116 IVVNNAGTVYPADLLSTKDEEITKTFEVNILGHFWITKALLPSMMERNHGHIVTVASVCG 175
Query: 88 RVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVRGVTRV 147
+ PY ++KFA GF L EL T C+ + + TR+
Sbjct: 176 HEGIPYLIPYCSSKFAAVGFHRGLTSELQALGKTGIKTSCLCPV--FVNTGFTKNPSTRL 233
Query: 148 -KAAPGPKAALAVIRGGATRAAGVFYPWRFRLLCLLRRWLPRPRAWFIRQELNV 200
+ ++I G T +F P + L+++LP + + + N+
Sbjct: 234 WPVLETDEVVRSLIDGILTNKKMIFVPSYINIFLRLQKFLPERASAILNRMQNI 287
>gi|22507405 short chain dehydrogenase/reductase family 9C, member 7
[Homo sapiens]
Length = 313
Score = 42.0 bits (97), Expect = 4e-04
Identities = 36/113 (31%), Positives = 50/113 (44%), Gaps = 16/113 (14%)
Query: 20 DNFDPGGLDYLVLNHIGGAPAGTRARSPQATRWL--------MQVNFVSYVQLTSRALPS 71
D GL LV N G P+G WL + VN V +++T LP
Sbjct: 95 DKVGEQGLWALVNNAGVGLPSGPN-------EWLTKDDFVKVINVNLVGLIEVTLHMLPM 147
Query: 72 LTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAI 124
+ ++G +V +SS GRV Y +KF ++ F S+RREL V V I
Sbjct: 148 VKRARGRVVNMSSSGGRVAV-IGGGYCVSKFGVEAFSDSIRRELYYFGVKVCI 199
>gi|50726952 retinol dehydrogenase 5 (11-cis and 9-cis) [Homo
sapiens]
Length = 318
Score = 40.8 bits (94), Expect = 8e-04
Identities = 27/89 (30%), Positives = 48/89 (53%), Gaps = 5/89 (5%)
Query: 40 AGTRARSPQATR----WLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFST 95
AG +P TR ++ VN + + +T LP L ++G ++ ++S+LGR+ +
Sbjct: 115 AGIIGPTPWLTRDDFQRVLNVNTMGPIGVTLALLPLLQQARGRVINITSVLGRLAAN-GG 173
Query: 96 PYSAAKFALDGFFGSLRRELDVQDVNVAI 124
Y +KF L+ F SLRR++ + V+I
Sbjct: 174 GYCVSKFGLEAFSDSLRRDVAHFGIRVSI 202
>gi|40548397 NADP-dependent retinol dehydrogenase/reductase [Homo
sapiens]
Length = 319
Score = 40.4 bits (93), Expect = 0.001
Identities = 22/70 (31%), Positives = 42/70 (60%), Gaps = 1/70 (1%)
Query: 54 MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 113
++VN + +T LP + ++G ++ VSS+ GR+ Y+ +K+A++GF SLRR
Sbjct: 134 IEVNLFGLISVTLNMLPLVKKAQGRVINVSSVGGRLAI-VGGGYTPSKYAVEGFNDSLRR 192
Query: 114 ELDVQDVNVA 123
++ V+V+
Sbjct: 193 DMKAFGVHVS 202
>gi|214010158 NADP-dependent retinol dehydrogenase/reductase [Homo
sapiens]
Length = 319
Score = 40.4 bits (93), Expect = 0.001
Identities = 22/70 (31%), Positives = 42/70 (60%), Gaps = 1/70 (1%)
Query: 54 MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 113
++VN + +T LP + ++G ++ VSS+ GR+ Y+ +K+A++GF SLRR
Sbjct: 134 IEVNLFGLISVTLNMLPLVKKAQGRVINVSSVGGRLAI-VGGGYTPSKYAVEGFNDSLRR 192
Query: 114 ELDVQDVNVA 123
++ V+V+
Sbjct: 193 DMKAFGVHVS 202
>gi|214010156 NADP-dependent retinol dehydrogenase/reductase [Homo
sapiens]
Length = 319
Score = 40.4 bits (93), Expect = 0.001
Identities = 22/70 (31%), Positives = 42/70 (60%), Gaps = 1/70 (1%)
Query: 54 MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 113
++VN + +T LP + ++G ++ VSS+ GR+ Y+ +K+A++GF SLRR
Sbjct: 134 IEVNLFGLISVTLNMLPLVKKAQGRVINVSSVGGRLAI-VGGGYTPSKYAVEGFNDSLRR 192
Query: 114 ELDVQDVNVA 123
++ V+V+
Sbjct: 193 DMKAFGVHVS 202
>gi|22758144 NADP-dependent retinol dehydrogenase/reductase [Homo
sapiens]
Length = 319
Score = 40.4 bits (93), Expect = 0.001
Identities = 22/70 (31%), Positives = 42/70 (60%), Gaps = 1/70 (1%)
Query: 54 MQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRR 113
++VN + +T LP + ++G ++ VSS+ GR+ Y+ +K+A++GF SLRR
Sbjct: 134 IEVNLFGLISVTLNMLPLVKKAQGRVINVSSVGGRLAI-VGGGYTPSKYAVEGFNDSLRR 192
Query: 114 ELDVQDVNVA 123
++ V+V+
Sbjct: 193 DMKAFGVHVS 202
>gi|119392083 hydroxysteroid (11-beta) dehydrogenase 2 [Homo
sapiens]
Length = 405
Score = 39.3 bits (90), Expect = 0.002
Identities = 29/80 (36%), Positives = 39/80 (48%), Gaps = 1/80 (1%)
Query: 46 SPQAT-RWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFAL 104
SP AT R M+VNF ++LT LP L S+G +V V S G +P Y +K A+
Sbjct: 180 SPVATFRSCMEVNFFGALELTKGLLPLLRSSRGRIVTVGSPAGDMPYPCLGAYGTSKAAV 239
Query: 105 DGFFGSLRRELDVQDVNVAI 124
+ EL V V+I
Sbjct: 240 ALLMDTFSCELLPWGVKVSI 259
>gi|223718074 hydroxysteroid (17-beta) dehydrogenase 1 [Homo
sapiens]
Length = 328
Score = 38.9 bits (89), Expect = 0.003
Identities = 31/104 (29%), Positives = 48/104 (46%), Gaps = 1/104 (0%)
Query: 25 GGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTD-SKGSLVVVS 83
G +D LV N G A A ++ VN V V++ LP + G ++V
Sbjct: 83 GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTG 142
Query: 84 SLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITMC 127
S+ G + F+ Y A+KFAL+G SL L V++++ C
Sbjct: 143 SVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIEC 186
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.138 0.427
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,543,540
Number of Sequences: 37866
Number of extensions: 309565
Number of successful extensions: 1031
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 987
Number of HSP's gapped (non-prelim): 53
length of query: 205
length of database: 18,247,518
effective HSP length: 97
effective length of query: 108
effective length of database: 14,574,516
effective search space: 1574047728
effective search space used: 1574047728
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.