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Search of human proteins with 38373690
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|38373690 COP9 signalosome subunit 4 [Homo sapiens]
(406 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|38373690 COP9 signalosome subunit 4 [Homo sapiens] 793 0.0
gi|4506221 proteasome 26S non-ATPase subunit 12 isoform 1 [Homo ... 84 3e-16
gi|28872765 proteasome 26S non-ATPase subunit 12 isoform 2 [Homo... 84 3e-16
gi|28872725 proteasome 26S non-ATPase subunit 11 [Homo sapiens] 39 0.006
gi|118918407 spectrin repeat containing, nuclear envelope 2 isof... 38 0.019
gi|118918403 spectrin repeat containing, nuclear envelope 2 isof... 38 0.019
gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens] 34 0.21
gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens] 34 0.21
gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens] 34 0.21
gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens] 34 0.21
gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens] 34 0.21
gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens] 34 0.21
gi|13899233 tetratricopeptide repeat domain 25 [Homo sapiens] 32 1.0
gi|23238222 COP9 constitutive photomorphogenic homolog subunit 3... 32 1.3
gi|47059046 dachsous 2 isoform 1 [Homo sapiens] 31 1.8
gi|6912630 interferon-induced protein with tetratricopeptide rep... 31 1.8
gi|115430239 spectrin, beta, non-erythrocytic 4 isoform sigma5 [... 31 1.8
gi|148612801 KIAA1009 protein [Homo sapiens] 31 1.8
gi|115430237 spectrin, beta, non-erythrocytic 4 isoform sigma1 [... 31 1.8
gi|47778943 syntaxin 16 isoform a [Homo sapiens] 31 2.3
gi|187608545 centrosomal protein 55kDa [Homo sapiens] 31 2.3
gi|187608537 centrosomal protein 55kDa [Homo sapiens] 31 2.3
gi|198041692 syntaxin 16 isoform d [Homo sapiens] 31 2.3
gi|198041688 syntaxin 16 isoform c [Homo sapiens] 31 2.3
gi|34447229 syntaxin 16 isoform b [Homo sapiens] 31 2.3
gi|157502195 proteasome 26S non-ATPase subunit 13 isoform 2 [Hom... 31 2.3
gi|157502193 proteasome 26S non-ATPase subunit 13 isoform 1 [Hom... 31 2.3
gi|49640011 tetratricopeptide repeat domain 3 [Homo sapiens] 31 2.3
gi|49640009 tetratricopeptide repeat domain 3 [Homo sapiens] 31 2.3
gi|21361633 leucine rich repeat containing 40 [Homo sapiens] 30 3.0
>gi|38373690 COP9 signalosome subunit 4 [Homo sapiens]
Length = 406
Score = 793 bits (2047), Expect = 0.0
Identities = 406/406 (100%), Positives = 406/406 (100%)
Query: 1 MAAAVRQDLAQLMNSSGSHKDLAGKYRQILEKAIQLSGAEQLEALKAFVEAMVNENVSLV 60
MAAAVRQDLAQLMNSSGSHKDLAGKYRQILEKAIQLSGAEQLEALKAFVEAMVNENVSLV
Sbjct: 1 MAAAVRQDLAQLMNSSGSHKDLAGKYRQILEKAIQLSGAEQLEALKAFVEAMVNENVSLV 60
Query: 61 ISRQLLTDFCTHLPNLPDSTAKEIYHFTLEKIQPRVISFEEQVASIRQHLASIYEKEEDW 120
ISRQLLTDFCTHLPNLPDSTAKEIYHFTLEKIQPRVISFEEQVASIRQHLASIYEKEEDW
Sbjct: 61 ISRQLLTDFCTHLPNLPDSTAKEIYHFTLEKIQPRVISFEEQVASIRQHLASIYEKEEDW 120
Query: 121 RNAAQVLVGIPLETGQKQYNVDYKLETYLKIARLYLEDDDPVQAEAYINRASLLQNESTN 180
RNAAQVLVGIPLETGQKQYNVDYKLETYLKIARLYLEDDDPVQAEAYINRASLLQNESTN
Sbjct: 121 RNAAQVLVGIPLETGQKQYNVDYKLETYLKIARLYLEDDDPVQAEAYINRASLLQNESTN 180
Query: 181 EQLQIHYKVCYARVLDYRRKFIEAAQRYNELSYKTIVHESERLEALKHALHCTILASAGQ 240
EQLQIHYKVCYARVLDYRRKFIEAAQRYNELSYKTIVHESERLEALKHALHCTILASAGQ
Sbjct: 181 EQLQIHYKVCYARVLDYRRKFIEAAQRYNELSYKTIVHESERLEALKHALHCTILASAGQ 240
Query: 241 QRSRMLATLFKDERCQQLAAYGILEKMYLDRIIRGNQLQEFAAMLMPHQKATTADGSSIL 300
QRSRMLATLFKDERCQQLAAYGILEKMYLDRIIRGNQLQEFAAMLMPHQKATTADGSSIL
Sbjct: 241 QRSRMLATLFKDERCQQLAAYGILEKMYLDRIIRGNQLQEFAAMLMPHQKATTADGSSIL 300
Query: 301 DRAVIEHNLLSASKLYNNITFEELGALLEIPAAKAEKIASQMITEGRMNGFIDQIDGIVH 360
DRAVIEHNLLSASKLYNNITFEELGALLEIPAAKAEKIASQMITEGRMNGFIDQIDGIVH
Sbjct: 301 DRAVIEHNLLSASKLYNNITFEELGALLEIPAAKAEKIASQMITEGRMNGFIDQIDGIVH 360
Query: 361 FETREALPTWDKQIQSLCFQVNNLLEKISQTAPEWTAQAMEAQMAQ 406
FETREALPTWDKQIQSLCFQVNNLLEKISQTAPEWTAQAMEAQMAQ
Sbjct: 361 FETREALPTWDKQIQSLCFQVNNLLEKISQTAPEWTAQAMEAQMAQ 406
>gi|4506221 proteasome 26S non-ATPase subunit 12 isoform 1 [Homo
sapiens]
Length = 456
Score = 83.6 bits (205), Expect = 3e-16
Identities = 86/370 (23%), Positives = 169/370 (45%), Gaps = 34/370 (9%)
Query: 52 MVNENVSLVISRQ---------LLTDFCTHLPNLPDSTAKEIYHFTLEKIQPRVISFEEQ 102
++NEN+ L+ R+ ++ CT++ + D K TL + I E +
Sbjct: 82 LLNENIMLLSKRRSQLKQAVAKMVQQCCTYVEEITDLPIKLRLIDTLRMVTEGKIYVEIE 141
Query: 103 VASIRQHLASIYEKEEDWRNAAQVLVGIPLETGQKQYNVDYKLETYLKIARLYLEDDDPV 162
A + + LA+I E+ D + AA +L + +ET + ++E L+ RL L D +
Sbjct: 142 RARLTKTLATIKEQNGDVKEAASILQELQVETYGSMEKKE-RVEFILEQMRLCLAVKDYI 200
Query: 163 QAEAYINRAS--LLQNESTNEQLQIHYKVCYARVLDYRRKFIEAAQRYNELSYKT--IVH 218
+ + + + Q E+T E+L++ Y ++ + ++ + Y + Y T I
Sbjct: 201 RTQIISKKINTKFFQEENT-EKLKLKYYNLMIQLDQHEGSYLSICKHYRAI-YDTPCIQA 258
Query: 219 ESERLE-ALKHALHCTILASAGQQRSRMLATLFKDERCQQLAAYGILEKMYLD-RIIRGN 276
ESE+ + ALK + ILA ++S ++ + D++ +++ Y L K++ ++R +
Sbjct: 259 ESEKWQQALKSVVLYVILAPFDNEQSDLVHRISGDKKLEEIPKYKDLLKLFTTMELMRWS 318
Query: 277 QLQEFAAMLMP----HQKATTADGSSI--------LDRAVIEHNLLSASKLYNNITFEEL 324
L E M + AT GS+ L V+EHN+ +K Y IT + +
Sbjct: 319 TLVEDYGMELRKGSLESPATDVFGSTEEGEKRWKDLKNRVVEHNIRIMAKYYTRITMKRM 378
Query: 325 GALLEIPAAKAEKIASQMITEGRMNGFIDQIDGIVHF----ETREALPTWDKQIQSLCFQ 380
LL++ ++E S ++ + +D++ GI++F + L W +++ SL
Sbjct: 379 AQLLDLSVDESEAFLSNLVVNKTIFAKVDRLAGIINFQRPKDPNNLLNDWSQKLNSLMSL 438
Query: 381 VNNLLEKISQ 390
VN I++
Sbjct: 439 VNKTTHLIAK 448
>gi|28872765 proteasome 26S non-ATPase subunit 12 isoform 2 [Homo
sapiens]
Length = 436
Score = 83.6 bits (205), Expect = 3e-16
Identities = 86/370 (23%), Positives = 169/370 (45%), Gaps = 34/370 (9%)
Query: 52 MVNENVSLVISRQ---------LLTDFCTHLPNLPDSTAKEIYHFTLEKIQPRVISFEEQ 102
++NEN+ L+ R+ ++ CT++ + D K TL + I E +
Sbjct: 62 LLNENIMLLSKRRSQLKQAVAKMVQQCCTYVEEITDLPIKLRLIDTLRMVTEGKIYVEIE 121
Query: 103 VASIRQHLASIYEKEEDWRNAAQVLVGIPLETGQKQYNVDYKLETYLKIARLYLEDDDPV 162
A + + LA+I E+ D + AA +L + +ET + ++E L+ RL L D +
Sbjct: 122 RARLTKTLATIKEQNGDVKEAASILQELQVETYGSMEKKE-RVEFILEQMRLCLAVKDYI 180
Query: 163 QAEAYINRAS--LLQNESTNEQLQIHYKVCYARVLDYRRKFIEAAQRYNELSYKT--IVH 218
+ + + + Q E+T E+L++ Y ++ + ++ + Y + Y T I
Sbjct: 181 RTQIISKKINTKFFQEENT-EKLKLKYYNLMIQLDQHEGSYLSICKHYRAI-YDTPCIQA 238
Query: 219 ESERLE-ALKHALHCTILASAGQQRSRMLATLFKDERCQQLAAYGILEKMYLD-RIIRGN 276
ESE+ + ALK + ILA ++S ++ + D++ +++ Y L K++ ++R +
Sbjct: 239 ESEKWQQALKSVVLYVILAPFDNEQSDLVHRISGDKKLEEIPKYKDLLKLFTTMELMRWS 298
Query: 277 QLQEFAAMLMP----HQKATTADGSSI--------LDRAVIEHNLLSASKLYNNITFEEL 324
L E M + AT GS+ L V+EHN+ +K Y IT + +
Sbjct: 299 TLVEDYGMELRKGSLESPATDVFGSTEEGEKRWKDLKNRVVEHNIRIMAKYYTRITMKRM 358
Query: 325 GALLEIPAAKAEKIASQMITEGRMNGFIDQIDGIVHF----ETREALPTWDKQIQSLCFQ 380
LL++ ++E S ++ + +D++ GI++F + L W +++ SL
Sbjct: 359 AQLLDLSVDESEAFLSNLVVNKTIFAKVDRLAGIINFQRPKDPNNLLNDWSQKLNSLMSL 418
Query: 381 VNNLLEKISQ 390
VN I++
Sbjct: 419 VNKTTHLIAK 428
>gi|28872725 proteasome 26S non-ATPase subunit 11 [Homo sapiens]
Length = 422
Score = 39.3 bits (90), Expect = 0.006
Identities = 22/88 (25%), Positives = 50/88 (56%), Gaps = 4/88 (4%)
Query: 304 VIEHNLLSASKLYNNITFEELGALLEIPAAKAEKIASQMITEGRMNGFIDQIDGI-VHFE 362
++E NL+ + ++ + E + +L+++ A E+ SQMI + + +G +DQ +G+ + F+
Sbjct: 330 LLEQNLIRVIEPFSRVQIEHISSLIKLSKADVERKLSQMILDKKFHGILDQGEGVLIIFD 389
Query: 363 TREALPTWD---KQIQSLCFQVNNLLEK 387
T++ + IQ++ V++L K
Sbjct: 390 EPPVDKTYEAALETIQNMSKVVDSLYNK 417
>gi|118918407 spectrin repeat containing, nuclear envelope 2 isoform 5
[Homo sapiens]
Length = 6907
Score = 37.7 bits (86), Expect = 0.019
Identities = 53/232 (22%), Positives = 94/232 (40%), Gaps = 42/232 (18%)
Query: 1 MAAAVRQDLAQLMNSSGSH-----KDLAGKYRQILEKAIQLSGAEQLE----------AL 45
+A V+ + L GS +DL +Y+ ++ K+ Q S +QLE A+
Sbjct: 2785 LAEEVKDKVPSLTTYEGSDLNNTLEDLRNQYQMLVLKSTQRS--QQLEFKLEERSNFFAI 2842
Query: 46 KAFVEAMVNENVSLVISRQLLTDFCTHLPNLPDSTAKEIYHFTLEKIQPRVISFEEQVAS 105
+ MV E+ +L+I R + + +H TLE Q + + +++
Sbjct: 2843 IRKFQLMVQESETLIIPR---------VETAATEAELKHHHVTLEASQKELQEIDSGIST 2893
Query: 106 IRQHLASIYEKEEDWRN--AAQVLVGIPLETGQKQ---YNVDYKLETYLKIARLYLEDDD 160
Q L +IYE+ + L + + T + Q N ++E +K R + E
Sbjct: 2894 HLQELTNIYEELNVFERLFLEDQLKNLKIRTNRIQRFIQNTCNEVEHKIKFCRQFHEKTS 2953
Query: 161 PVQAEA-YINRASLLQNESTNEQLQ----------IHYKVCYARVLDYRRKF 201
+Q EA I R LL N+ N+ ++ K C +VL ++ F
Sbjct: 2954 ALQEEADSIQRNELLLNQEVNKGVKEEIYNLKDRLTAIKCCILQVLKLKKVF 3005
>gi|118918403 spectrin repeat containing, nuclear envelope 2 isoform 1
[Homo sapiens]
Length = 6885
Score = 37.7 bits (86), Expect = 0.019
Identities = 53/232 (22%), Positives = 94/232 (40%), Gaps = 42/232 (18%)
Query: 1 MAAAVRQDLAQLMNSSGSH-----KDLAGKYRQILEKAIQLSGAEQLE----------AL 45
+A V+ + L GS +DL +Y+ ++ K+ Q S +QLE A+
Sbjct: 2785 LAEEVKDKVPSLTTYEGSDLNNTLEDLRNQYQMLVLKSTQRS--QQLEFKLEERSNFFAI 2842
Query: 46 KAFVEAMVNENVSLVISRQLLTDFCTHLPNLPDSTAKEIYHFTLEKIQPRVISFEEQVAS 105
+ MV E+ +L+I R + + +H TLE Q + + +++
Sbjct: 2843 IRKFQLMVQESETLIIPR---------VETAATEAELKHHHVTLEASQKELQEIDSGIST 2893
Query: 106 IRQHLASIYEKEEDWRN--AAQVLVGIPLETGQKQ---YNVDYKLETYLKIARLYLEDDD 160
Q L +IYE+ + L + + T + Q N ++E +K R + E
Sbjct: 2894 HLQELTNIYEELNVFERLFLEDQLKNLKIRTNRIQRFIQNTCNEVEHKIKFCRQFHEKTS 2953
Query: 161 PVQAEA-YINRASLLQNESTNEQLQ----------IHYKVCYARVLDYRRKF 201
+Q EA I R LL N+ N+ ++ K C +VL ++ F
Sbjct: 2954 ALQEEADSIQRNELLLNQEVNKGVKEEIYNLKDRLTAIKCCILQVLKLKKVF 3005
>gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens]
Length = 983
Score = 34.3 bits (77), Expect = 0.21
Identities = 50/229 (21%), Positives = 94/229 (41%), Gaps = 38/229 (16%)
Query: 4 AVRQDLAQLMN-SSGSHKDLAGKYRQILEKAIQLSGAEQLEALKAFVEAMVNENVSLVIS 62
A + L QL N S +D + + K + +L LK V+A +VS+
Sbjct: 682 AEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLN-----ELTQLKQLVDAQKENSVSITEH 736
Query: 63 RQLLTDFCTHLPNLPDSTAKEIYHFTLEKIQPRVISFEEQVASIRQHLAS------IYEK 116
Q++T T AKE+ EE+++++++HLAS EK
Sbjct: 737 LQVITTLRT--------AAKEM---------------EEKISNLKEHLASKEVEVAKLEK 773
Query: 117 EEDWRNAAQVLVGIPLETGQK-QYNVDYKLETYLKIARLYLEDDDPVQAEAYINRASLLQ 175
+ AA +P + +K Q +++ ++ + +++ + V +E R+ + Q
Sbjct: 774 QLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQ 833
Query: 176 NESTNEQLQIHYKVCYARVLDYRRKFIEAAQRYNELSYKTIVHESERLE 224
+ E +Q K V + +KF +A + E+ K S +LE
Sbjct: 834 VKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEM--KRYAESSSKLE 880
>gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens]
Length = 972
Score = 34.3 bits (77), Expect = 0.21
Identities = 50/229 (21%), Positives = 94/229 (41%), Gaps = 38/229 (16%)
Query: 4 AVRQDLAQLMN-SSGSHKDLAGKYRQILEKAIQLSGAEQLEALKAFVEAMVNENVSLVIS 62
A + L QL N S +D + + K + +L LK V+A +VS+
Sbjct: 671 AEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLN-----ELTQLKQLVDAQKENSVSITEH 725
Query: 63 RQLLTDFCTHLPNLPDSTAKEIYHFTLEKIQPRVISFEEQVASIRQHLAS------IYEK 116
Q++T T AKE+ EE+++++++HLAS EK
Sbjct: 726 LQVITTLRT--------AAKEM---------------EEKISNLKEHLASKEVEVAKLEK 762
Query: 117 EEDWRNAAQVLVGIPLETGQK-QYNVDYKLETYLKIARLYLEDDDPVQAEAYINRASLLQ 175
+ AA +P + +K Q +++ ++ + +++ + V +E R+ + Q
Sbjct: 763 QLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQ 822
Query: 176 NESTNEQLQIHYKVCYARVLDYRRKFIEAAQRYNELSYKTIVHESERLE 224
+ E +Q K V + +KF +A + E+ K S +LE
Sbjct: 823 VKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEM--KRYAESSSKLE 869
>gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens]
Length = 951
Score = 34.3 bits (77), Expect = 0.21
Identities = 50/229 (21%), Positives = 94/229 (41%), Gaps = 38/229 (16%)
Query: 4 AVRQDLAQLMN-SSGSHKDLAGKYRQILEKAIQLSGAEQLEALKAFVEAMVNENVSLVIS 62
A + L QL N S +D + + K + +L LK V+A +VS+
Sbjct: 650 AEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLN-----ELTQLKQLVDAQKENSVSITEH 704
Query: 63 RQLLTDFCTHLPNLPDSTAKEIYHFTLEKIQPRVISFEEQVASIRQHLAS------IYEK 116
Q++T T AKE+ EE+++++++HLAS EK
Sbjct: 705 LQVITTLRT--------AAKEM---------------EEKISNLKEHLASKEVEVAKLEK 741
Query: 117 EEDWRNAAQVLVGIPLETGQK-QYNVDYKLETYLKIARLYLEDDDPVQAEAYINRASLLQ 175
+ AA +P + +K Q +++ ++ + +++ + V +E R+ + Q
Sbjct: 742 QLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQ 801
Query: 176 NESTNEQLQIHYKVCYARVLDYRRKFIEAAQRYNELSYKTIVHESERLE 224
+ E +Q K V + +KF +A + E+ K S +LE
Sbjct: 802 VKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEM--KRYAESSSKLE 848
>gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 34.3 bits (77), Expect = 0.21
Identities = 50/229 (21%), Positives = 94/229 (41%), Gaps = 38/229 (16%)
Query: 4 AVRQDLAQLMN-SSGSHKDLAGKYRQILEKAIQLSGAEQLEALKAFVEAMVNENVSLVIS 62
A + L QL N S +D + + K + +L LK V+A +VS+
Sbjct: 679 AEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLN-----ELTQLKQLVDAQKENSVSITEH 733
Query: 63 RQLLTDFCTHLPNLPDSTAKEIYHFTLEKIQPRVISFEEQVASIRQHLAS------IYEK 116
Q++T T AKE+ EE+++++++HLAS EK
Sbjct: 734 LQVITTLRT--------AAKEM---------------EEKISNLKEHLASKEVEVAKLEK 770
Query: 117 EEDWRNAAQVLVGIPLETGQK-QYNVDYKLETYLKIARLYLEDDDPVQAEAYINRASLLQ 175
+ AA +P + +K Q +++ ++ + +++ + V +E R+ + Q
Sbjct: 771 QLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQ 830
Query: 176 NESTNEQLQIHYKVCYARVLDYRRKFIEAAQRYNELSYKTIVHESERLE 224
+ E +Q K V + +KF +A + E+ K S +LE
Sbjct: 831 VKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEM--KRYAESSSKLE 877
>gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 34.3 bits (77), Expect = 0.21
Identities = 50/229 (21%), Positives = 94/229 (41%), Gaps = 38/229 (16%)
Query: 4 AVRQDLAQLMN-SSGSHKDLAGKYRQILEKAIQLSGAEQLEALKAFVEAMVNENVSLVIS 62
A + L QL N S +D + + K + +L LK V+A +VS+
Sbjct: 679 AEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLN-----ELTQLKQLVDAQKENSVSITEH 733
Query: 63 RQLLTDFCTHLPNLPDSTAKEIYHFTLEKIQPRVISFEEQVASIRQHLAS------IYEK 116
Q++T T AKE+ EE+++++++HLAS EK
Sbjct: 734 LQVITTLRT--------AAKEM---------------EEKISNLKEHLASKEVEVAKLEK 770
Query: 117 EEDWRNAAQVLVGIPLETGQK-QYNVDYKLETYLKIARLYLEDDDPVQAEAYINRASLLQ 175
+ AA +P + +K Q +++ ++ + +++ + V +E R+ + Q
Sbjct: 771 QLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQ 830
Query: 176 NESTNEQLQIHYKVCYARVLDYRRKFIEAAQRYNELSYKTIVHESERLE 224
+ E +Q K V + +KF +A + E+ K S +LE
Sbjct: 831 VKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEM--KRYAESSSKLE 877
>gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 34.3 bits (77), Expect = 0.21
Identities = 50/229 (21%), Positives = 94/229 (41%), Gaps = 38/229 (16%)
Query: 4 AVRQDLAQLMN-SSGSHKDLAGKYRQILEKAIQLSGAEQLEALKAFVEAMVNENVSLVIS 62
A + L QL N S +D + + K + +L LK V+A +VS+
Sbjct: 679 AEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLN-----ELTQLKQLVDAQKENSVSITEH 733
Query: 63 RQLLTDFCTHLPNLPDSTAKEIYHFTLEKIQPRVISFEEQVASIRQHLAS------IYEK 116
Q++T T AKE+ EE+++++++HLAS EK
Sbjct: 734 LQVITTLRT--------AAKEM---------------EEKISNLKEHLASKEVEVAKLEK 770
Query: 117 EEDWRNAAQVLVGIPLETGQK-QYNVDYKLETYLKIARLYLEDDDPVQAEAYINRASLLQ 175
+ AA +P + +K Q +++ ++ + +++ + V +E R+ + Q
Sbjct: 771 QLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQ 830
Query: 176 NESTNEQLQIHYKVCYARVLDYRRKFIEAAQRYNELSYKTIVHESERLE 224
+ E +Q K V + +KF +A + E+ K S +LE
Sbjct: 831 VKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEM--KRYAESSSKLE 877
>gi|13899233 tetratricopeptide repeat domain 25 [Homo sapiens]
Length = 672
Score = 32.0 bits (71), Expect = 1.0
Identities = 23/82 (28%), Positives = 38/82 (46%), Gaps = 1/82 (1%)
Query: 150 KIARLYLEDDDPVQAEAYINRASLLQNESTNEQLQIHYKVCYARVLDYRRKFIEAAQRYN 209
+I R YLE D QA+ Y ++ E + + Q++ V A+ R F A +
Sbjct: 402 EIGRCYLELDQAWQAQNYGEKSQQCAEEEGDIEWQLNASVLVAQAQVKLRDFESAVNNFE 461
Query: 210 E-LSYKTIVHESERLEALKHAL 230
+ L +VH +E +A+ AL
Sbjct: 462 KALERAKLVHNNEAQQAIISAL 483
>gi|23238222 COP9 constitutive photomorphogenic homolog subunit 3
[Homo sapiens]
Length = 423
Score = 31.6 bits (70), Expect = 1.3
Identities = 21/98 (21%), Positives = 48/98 (48%), Gaps = 5/98 (5%)
Query: 269 LDRIIRGNQLQEFAAMLMPHQKATTADGSSILDR----AVIEHNLLSASKLYNNITFEEL 324
L ++ N E ++ H + T D + L + ++ + N+ +K + ++ +++
Sbjct: 263 LAQVYSTNNPSELRNLVNKHSETFTRDNNMGLVKQCLSSLYKKNIQRLTKTFLTLSLQDM 322
Query: 325 GALLEIPAAK-AEKIASQMITEGRMNGFIDQIDGIVHF 361
+ +++ + AEK MI +G + I+Q DG+V F
Sbjct: 323 ASRVQLSGPQEAEKYVLHMIEDGEIFASINQKDGMVSF 360
>gi|47059046 dachsous 2 isoform 1 [Homo sapiens]
Length = 2916
Score = 31.2 bits (69), Expect = 1.8
Identities = 49/226 (21%), Positives = 84/226 (37%), Gaps = 34/226 (15%)
Query: 132 LETGQKQYNVDYKLETYLKIARLYLEDDDPVQAEAYINRASLLQNESTNEQLQIHYKVCY 191
+E G + N +Y E +K L L +D V + + S + ++ T E + Y +
Sbjct: 2080 VEIGIEDMN-NYAPEFTVKSYNLSLSEDALVGST--LVTFSNIDHDWTRENTYVEYSIIS 2136
Query: 192 ARVLD---YRRKFIEAAQRYNELSYKTIVHESERLEALKHALHCTILASAGQQRSRMLAT 248
+ KF + Y ++ Y ++H +R + H L ILAS
Sbjct: 2137 GNSQNNFHVETKFFHSEYPYKQVGYLVLLHSLDREASASHEL--VILAS----------- 2183
Query: 249 LFKDERCQQLAAYGILEKMYLDRIIRGNQLQEFAAMLMPHQKATTADGSSIL-------- 300
D C L++ ++ LD + N + H K +T GS I
Sbjct: 2184 ---DSGCPPLSSTAVISIQVLD--VNDNPPNFSSLSYHTHVKESTPLGSHITVVSANDRD 2238
Query: 301 --DRAVIEHNLLSASKLYNNITFEELGALLEIPAAKAEKIASQMIT 344
A I +N++S ++ + E G L I EK+ +T
Sbjct: 2239 TGSHAEIIYNIISGNEKGHFYLEENTGVLYLIKPLDYEKMTKFTLT 2284
>gi|6912630 interferon-induced protein with tetratricopeptide
repeats 5 [Homo sapiens]
Length = 482
Score = 31.2 bits (69), Expect = 1.8
Identities = 25/80 (31%), Positives = 35/80 (43%), Gaps = 15/80 (18%)
Query: 148 YLKIARLYLEDDDPVQAEAYINRASLLQNESTNEQLQIHYKVCYARVLDYRRKFIEAAQR 207
Y +A +Y E AE +A L+N + + + QIHY Y R ++ RK
Sbjct: 341 YTDLANMYAEGGQYSNAEDIFRKALRLENITDDHKHQIHYH--YGRFQEFHRK------- 391
Query: 208 YNELSYKTIVHESERLEALK 227
S T +H LEALK
Sbjct: 392 ----SENTAIH--HYLEALK 405
>gi|115430239 spectrin, beta, non-erythrocytic 4 isoform sigma5
[Homo sapiens]
Length = 678
Score = 31.2 bits (69), Expect = 1.8
Identities = 32/114 (28%), Positives = 54/114 (47%), Gaps = 13/114 (11%)
Query: 2 AAAVRQDLAQLMNSSGSHKDLAGKYRQILEKAIQLSGAEQLEALKAFVEAMVNENVSLVI 61
A AVR+ L QL ++ ++ A + +Q+L+ A Q+ EQ A VEA + E L++
Sbjct: 265 AEAVRRGLEQLQSAWAGLREAAERRQQVLDAAFQV---EQYYFDVAEVEAWLGEQELLMM 321
Query: 62 SRQLLTDFCTHLPNLPDSTAKEIYHFTLEKIQPRVISFEEQVASIRQHLASIYE 115
S D + L L H LE+ V ++EE +A + + ++ E
Sbjct: 322 SEDKGKDEQSTLQLLKK-------HLQLEQ---GVENYEESIAQLSRQCRALLE 365
>gi|148612801 KIAA1009 protein [Homo sapiens]
Length = 1403
Score = 31.2 bits (69), Expect = 1.8
Identities = 27/112 (24%), Positives = 51/112 (45%), Gaps = 4/112 (3%)
Query: 113 IYEKEEDWRNAAQVLVGIPLETGQKQYNVDYKLETYLKIARLYLEDDDPVQAEAYINRAS 172
+ E E+ WR A ++ I +K+ ++ KLE ++ + ++ + + YI +A
Sbjct: 619 VQEAEDKWRGAQALIEQIKATFSEKEKELENKLE---ELKKQQEKELFKLNQDNYILQAK 675
Query: 173 LLQNESTN-EQLQIHYKVCYARVLDYRRKFIEAAQRYNELSYKTIVHESERL 223
L E TN +Q +H+ V + K I+ + E + E+ERL
Sbjct: 676 LSSFEETNKKQRWLHFGEAADPVTGEKLKQIQKEIQEQETLLQGYQQENERL 727
>gi|115430237 spectrin, beta, non-erythrocytic 4 isoform sigma1 [Homo
sapiens]
Length = 2564
Score = 31.2 bits (69), Expect = 1.8
Identities = 32/114 (28%), Positives = 54/114 (47%), Gaps = 13/114 (11%)
Query: 2 AAAVRQDLAQLMNSSGSHKDLAGKYRQILEKAIQLSGAEQLEALKAFVEAMVNENVSLVI 61
A AVR+ L QL ++ ++ A + +Q+L+ A Q+ EQ A VEA + E L++
Sbjct: 1589 AEAVRRGLEQLQSAWAGLREAAERRQQVLDAAFQV---EQYYFDVAEVEAWLGEQELLMM 1645
Query: 62 SRQLLTDFCTHLPNLPDSTAKEIYHFTLEKIQPRVISFEEQVASIRQHLASIYE 115
S D + L L H LE+ V ++EE +A + + ++ E
Sbjct: 1646 SEDKGKDEQSTLQLLKK-------HLQLEQ---GVENYEESIAQLSRQCRALLE 1689
>gi|47778943 syntaxin 16 isoform a [Homo sapiens]
Length = 325
Score = 30.8 bits (68), Expect = 2.3
Identities = 23/83 (27%), Positives = 40/83 (48%), Gaps = 9/83 (10%)
Query: 69 FCTHLPNLPDSTAKEIYH--FTLEK---IQPRVISFEEQVASIRQHLASIYEKEEDWRNA 123
F T +P + D +YH FT ++ ++ + EE+ IRQ + SI + E +R+
Sbjct: 198 FDTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIVQSISDLNEIFRDL 257
Query: 124 AQVLVGIPLETGQKQYNVDYKLE 146
++V E G +DY +E
Sbjct: 258 GAMIV----EQGTVLDRIDYNVE 276
>gi|187608545 centrosomal protein 55kDa [Homo sapiens]
Length = 464
Score = 30.8 bits (68), Expect = 2.3
Identities = 58/293 (19%), Positives = 117/293 (39%), Gaps = 33/293 (11%)
Query: 24 GKYRQILEKAIQLSGAEQLEALKAFVEAMVNENVSLVISRQLLTDFCTHLPNLPDSTAKE 83
G+ R+ + KA+ +E+ + LK + A + L L T PN +S+
Sbjct: 111 GERREQVLKAL----SEEKDVLKQQLSAATSRIAELESKTNTLRLSQTVAPNCFNSSINN 166
Query: 84 IYHF------TLEKIQPRVISFEEQVASIRQHLASIYEKEEDWRNAAQVLVGIPLETGQK 137
I+ LEK Q ++ +++ ++ LA I+E E+ AA +P +T +
Sbjct: 167 IHEMEIQLKDALEKNQQWLVYDQQREVYVKGLLAKIFELEKKTETAAH---SLPQQTKKP 223
Query: 138 QYNVDYKLETYLKIARLYLEDDDPVQAEAYINRASLLQNESTNEQLQIHYKVCYARVLDY 197
+ E YL+ + +D A + L T QL + ++
Sbjct: 224 E------SEGYLQEEKQKCYNDLLASA-----KKDLEVERQTITQLSF-------ELSEF 265
Query: 198 RRKFIEAAQRYNELSYKTIVHESERLEALKHALHCTILASAGQQRSRMLATLFKDERCQQ 257
RRK+ E + + L+ ++ L+ H T ++ + + ++E+ +
Sbjct: 266 RRKYEETQKEVHNLNQLLYSQRRADVQHLEDDRHKTEKIQKLREENDIARGKLEEEKKRS 325
Query: 258 LAAYGILEKMYLDRIIRGNQLQEFAAMLMPHQKATTAD-GSSILDRAVIEHNL 309
++ +Y +++ + Q A+L +A T D + LDR ++H L
Sbjct: 326 EELLSQVQFLYTS-LLKQQEEQTRVALLEQQMQACTLDFENEKLDRQHVQHQL 377
Score = 30.4 bits (67), Expect = 3.0
Identities = 32/144 (22%), Positives = 65/144 (45%), Gaps = 14/144 (9%)
Query: 133 ETGQKQYNVDYKLETYLKIARLYLEDD-------DPVQAEAYINRASLLQNESTNEQLQI 185
ET ++ +N++ L + + +LEDD ++ E I R L + + +E+L
Sbjct: 271 ETQKEVHNLNQLLYSQRRADVQHLEDDRHKTEKIQKLREENDIARGKLEEEKKRSEELLS 330
Query: 186 HYKVCYARVLDYRRKFIEAAQRYNELSYKTIVHESERLEA--LKHALHCTILASAGQQRS 243
+ Y +L + + A ++ T+ E+E+L+ ++H LH IL + R+
Sbjct: 331 QVQFLYTSLLKQQEEQTRVALLEQQMQACTLDFENEKLDRQHVQHQLH-VILKELRKARN 389
Query: 244 RMLATLFKDERCQQLAAYGILEKM 267
++ E +QL + I E +
Sbjct: 390 QITQL----ESLKQLHEFAITEPL 409
>gi|187608537 centrosomal protein 55kDa [Homo sapiens]
Length = 464
Score = 30.8 bits (68), Expect = 2.3
Identities = 58/293 (19%), Positives = 117/293 (39%), Gaps = 33/293 (11%)
Query: 24 GKYRQILEKAIQLSGAEQLEALKAFVEAMVNENVSLVISRQLLTDFCTHLPNLPDSTAKE 83
G+ R+ + KA+ +E+ + LK + A + L L T PN +S+
Sbjct: 111 GERREQVLKAL----SEEKDVLKQQLSAATSRIAELESKTNTLRLSQTVAPNCFNSSINN 166
Query: 84 IYHF------TLEKIQPRVISFEEQVASIRQHLASIYEKEEDWRNAAQVLVGIPLETGQK 137
I+ LEK Q ++ +++ ++ LA I+E E+ AA +P +T +
Sbjct: 167 IHEMEIQLKDALEKNQQWLVYDQQREVYVKGLLAKIFELEKKTETAAH---SLPQQTKKP 223
Query: 138 QYNVDYKLETYLKIARLYLEDDDPVQAEAYINRASLLQNESTNEQLQIHYKVCYARVLDY 197
+ E YL+ + +D A + L T QL + ++
Sbjct: 224 E------SEGYLQEEKQKCYNDLLASA-----KKDLEVERQTITQLSF-------ELSEF 265
Query: 198 RRKFIEAAQRYNELSYKTIVHESERLEALKHALHCTILASAGQQRSRMLATLFKDERCQQ 257
RRK+ E + + L+ ++ L+ H T ++ + + ++E+ +
Sbjct: 266 RRKYEETQKEVHNLNQLLYSQRRADVQHLEDDRHKTEKIQKLREENDIARGKLEEEKKRS 325
Query: 258 LAAYGILEKMYLDRIIRGNQLQEFAAMLMPHQKATTAD-GSSILDRAVIEHNL 309
++ +Y +++ + Q A+L +A T D + LDR ++H L
Sbjct: 326 EELLSQVQFLYTS-LLKQQEEQTRVALLEQQMQACTLDFENEKLDRQHVQHQL 377
Score = 30.4 bits (67), Expect = 3.0
Identities = 32/144 (22%), Positives = 65/144 (45%), Gaps = 14/144 (9%)
Query: 133 ETGQKQYNVDYKLETYLKIARLYLEDD-------DPVQAEAYINRASLLQNESTNEQLQI 185
ET ++ +N++ L + + +LEDD ++ E I R L + + +E+L
Sbjct: 271 ETQKEVHNLNQLLYSQRRADVQHLEDDRHKTEKIQKLREENDIARGKLEEEKKRSEELLS 330
Query: 186 HYKVCYARVLDYRRKFIEAAQRYNELSYKTIVHESERLEA--LKHALHCTILASAGQQRS 243
+ Y +L + + A ++ T+ E+E+L+ ++H LH IL + R+
Sbjct: 331 QVQFLYTSLLKQQEEQTRVALLEQQMQACTLDFENEKLDRQHVQHQLH-VILKELRKARN 389
Query: 244 RMLATLFKDERCQQLAAYGILEKM 267
++ E +QL + I E +
Sbjct: 390 QITQL----ESLKQLHEFAITEPL 409
>gi|198041692 syntaxin 16 isoform d [Homo sapiens]
Length = 308
Score = 30.8 bits (68), Expect = 2.3
Identities = 23/83 (27%), Positives = 40/83 (48%), Gaps = 9/83 (10%)
Query: 69 FCTHLPNLPDSTAKEIYH--FTLEK---IQPRVISFEEQVASIRQHLASIYEKEEDWRNA 123
F T +P + D +YH FT ++ ++ + EE+ IRQ + SI + E +R+
Sbjct: 181 FDTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIVQSISDLNEIFRDL 240
Query: 124 AQVLVGIPLETGQKQYNVDYKLE 146
++V E G +DY +E
Sbjct: 241 GAMIV----EQGTVLDRIDYNVE 259
>gi|198041688 syntaxin 16 isoform c [Homo sapiens]
Length = 321
Score = 30.8 bits (68), Expect = 2.3
Identities = 23/83 (27%), Positives = 40/83 (48%), Gaps = 9/83 (10%)
Query: 69 FCTHLPNLPDSTAKEIYH--FTLEK---IQPRVISFEEQVASIRQHLASIYEKEEDWRNA 123
F T +P + D +YH FT ++ ++ + EE+ IRQ + SI + E +R+
Sbjct: 194 FDTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIVQSISDLNEIFRDL 253
Query: 124 AQVLVGIPLETGQKQYNVDYKLE 146
++V E G +DY +E
Sbjct: 254 GAMIV----EQGTVLDRIDYNVE 272
>gi|34447229 syntaxin 16 isoform b [Homo sapiens]
Length = 304
Score = 30.8 bits (68), Expect = 2.3
Identities = 23/83 (27%), Positives = 40/83 (48%), Gaps = 9/83 (10%)
Query: 69 FCTHLPNLPDSTAKEIYH--FTLEK---IQPRVISFEEQVASIRQHLASIYEKEEDWRNA 123
F T +P + D +YH FT ++ ++ + EE+ IRQ + SI + E +R+
Sbjct: 177 FDTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIVQSISDLNEIFRDL 236
Query: 124 AQVLVGIPLETGQKQYNVDYKLE 146
++V E G +DY +E
Sbjct: 237 GAMIV----EQGTVLDRIDYNVE 255
>gi|157502195 proteasome 26S non-ATPase subunit 13 isoform 2 [Homo
sapiens]
Length = 378
Score = 30.8 bits (68), Expect = 2.3
Identities = 13/45 (28%), Positives = 25/45 (55%)
Query: 316 YNNITFEELGALLEIPAAKAEKIASQMITEGRMNGFIDQIDGIVH 360
+ +TFEE+ +I + E + + ++ G + G ID++D VH
Sbjct: 290 HRQLTFEEIAKSAKITVNEVELLVMKALSVGLVKGSIDEVDKRVH 334
>gi|157502193 proteasome 26S non-ATPase subunit 13 isoform 1 [Homo
sapiens]
Length = 376
Score = 30.8 bits (68), Expect = 2.3
Identities = 13/45 (28%), Positives = 25/45 (55%)
Query: 316 YNNITFEELGALLEIPAAKAEKIASQMITEGRMNGFIDQIDGIVH 360
+ +TFEE+ +I + E + + ++ G + G ID++D VH
Sbjct: 288 HRQLTFEEIAKSAKITVNEVELLVMKALSVGLVKGSIDEVDKRVH 332
>gi|49640011 tetratricopeptide repeat domain 3 [Homo sapiens]
Length = 2025
Score = 30.8 bits (68), Expect = 2.3
Identities = 42/173 (24%), Positives = 75/173 (43%), Gaps = 19/173 (10%)
Query: 19 HKDLAGKYRQILE--KAIQLSGAEQLEALKAFVEAMVNENVSLVISRQLLTDFCTHLPNL 76
H+ L + +++ E + I+L G E+ L+ ++ + EN IS+ L F L
Sbjct: 1499 HQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENK---ISKTELDWFLQDLE-- 1553
Query: 77 PDSTAKEIYHFTLEK--IQPRVISFEEQVASIRQHLASIYEKEEDWRNAAQVLVGIPLET 134
+EI + EK IQ R+ S ++++ + +K + ++ + LE
Sbjct: 1554 -----REIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEHELHLDQSLEI 1608
Query: 135 GQKQYNVDYKLETYLKIARLYLEDDDPVQAEAYINRASLLQN--ESTNEQLQI 185
N K+E Y+K + ED + A S+L+N ES +LQI
Sbjct: 1609 SNTLTNEKMKIEEYIKKGK---EDYEESHQRAVAAEVSVLENWKESEVYKLQI 1658
>gi|49640009 tetratricopeptide repeat domain 3 [Homo sapiens]
Length = 2025
Score = 30.8 bits (68), Expect = 2.3
Identities = 42/173 (24%), Positives = 75/173 (43%), Gaps = 19/173 (10%)
Query: 19 HKDLAGKYRQILE--KAIQLSGAEQLEALKAFVEAMVNENVSLVISRQLLTDFCTHLPNL 76
H+ L + +++ E + I+L G E+ L+ ++ + EN IS+ L F L
Sbjct: 1499 HQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENK---ISKTELDWFLQDLE-- 1553
Query: 77 PDSTAKEIYHFTLEK--IQPRVISFEEQVASIRQHLASIYEKEEDWRNAAQVLVGIPLET 134
+EI + EK IQ R+ S ++++ + +K + ++ + LE
Sbjct: 1554 -----REIKKWQQEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEHELHLDQSLEI 1608
Query: 135 GQKQYNVDYKLETYLKIARLYLEDDDPVQAEAYINRASLLQN--ESTNEQLQI 185
N K+E Y+K + ED + A S+L+N ES +LQI
Sbjct: 1609 SNTLTNEKMKIEEYIKKGK---EDYEESHQRAVAAEVSVLENWKESEVYKLQI 1658
>gi|21361633 leucine rich repeat containing 40 [Homo sapiens]
Length = 602
Score = 30.4 bits (67), Expect = 3.0
Identities = 23/74 (31%), Positives = 38/74 (51%), Gaps = 5/74 (6%)
Query: 127 LVGIPLETGQKQYNVDYKLETYLKIARLYLEDDDPVQAEAYINRASLLQNESTNEQLQIH 186
L G PL T +++ + + LK R ++DD P Q+E+ A L +ES ++ IH
Sbjct: 341 LEGNPLRTIRREI-ISKGTQEVLKYLRSKIKDDGPSQSESATETAMTLPSES---RVNIH 396
Query: 187 YKVCYARVLDYRRK 200
+ ++LDY K
Sbjct: 397 -AIITLKILDYSDK 409
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.131 0.362
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,610,761
Number of Sequences: 37866
Number of extensions: 490920
Number of successful extensions: 1507
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 31
Number of HSP's that attempted gapping in prelim test: 1488
Number of HSP's gapped (non-prelim): 46
length of query: 406
length of database: 18,247,518
effective HSP length: 105
effective length of query: 301
effective length of database: 14,271,588
effective search space: 4295747988
effective search space used: 4295747988
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.