Guide to the Human Genome
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Search of human proteins with 38327039

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|38327039 heat shock 70kDa protein 4 [Homo sapiens]
         (840 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|38327039 heat shock 70kDa protein 4 [Homo sapiens]                1665   0.0  
gi|31541941 heat shock 70kDa protein 4-like [Homo sapiens]           1088   0.0  
gi|42544159 heat shock 105kD [Homo sapiens]                          1082   0.0  
gi|195976805 hypoxia up-regulated 1 precursor [Homo sapiens]          314   2e-85
gi|5453832 hypoxia up-regulated 1 precursor [Homo sapiens]            314   2e-85
gi|34419635 heat shock 70kDa protein 6 (HSP70B') [Homo sapiens]       301   2e-81
gi|167466173 heat shock 70kDa protein 1B [Homo sapiens]               294   3e-79
gi|194248072 heat shock 70kDa protein 1A [Homo sapiens]               294   3e-79
gi|124256496 heat shock 70kDa protein 1-like [Homo sapiens]           293   6e-79
gi|5729877 heat shock 70kDa protein 8 isoform 1 [Homo sapiens]        288   1e-77
gi|16507237 heat shock 70kDa protein 5 [Homo sapiens]                 284   2e-76
gi|13676857 heat shock 70kDa protein 2 [Homo sapiens]                 271   2e-72
gi|24234686 heat shock 70kDa protein 8 isoform 2 [Homo sapiens]       270   5e-72
gi|24234688 heat shock 70kDa protein 9 precursor [Homo sapiens]       219   8e-57
gi|82880658 heat shock 70kDa protein 14 isoform 1 [Homo sapiens]      191   2e-48
gi|48928056 heat shock protein 70kDa family member 13 precursor ...   163   7e-40
gi|221219020 NYD-SP11 protein [Homo sapiens]                           60   1e-08
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m...    60   1e-08
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m...    60   1e-08
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li...    59   1e-08
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li...    58   3e-08
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]                       55   2e-07
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa...    55   3e-07
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap...    54   5e-07
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)...    53   1e-06
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi...    52   2e-06
gi|239752551 PREDICTED: hypothetical protein [Homo sapiens]            52   2e-06
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik...    51   5e-06
gi|8922950 meiosis-specific nuclear structural 1 [Homo sapiens]        50   1e-05
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa...    49   2e-05

>gi|38327039 heat shock 70kDa protein 4 [Homo sapiens]
          Length = 840

 Score = 1665 bits (4312), Expect = 0.0
 Identities = 840/840 (100%), Positives = 840/840 (100%)

Query: 1   MSVVGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISNA 60
           MSVVGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISNA
Sbjct: 1   MSVVGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISNA 60

Query: 61  KNTVQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTAM 120
           KNTVQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTAM
Sbjct: 61  KNTVQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTAM 120

Query: 121 LLSKLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVALA 180
           LLSKLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVALA
Sbjct: 121 LLSKLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVALA 180

Query: 181 YGIYKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVL 240
           YGIYKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVL
Sbjct: 181 YGIYKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVL 240

Query: 241 VNHFCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMNDVDVSGT 300
           VNHFCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMNDVDVSGT
Sbjct: 241 VNHFCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMNDVDVSGT 300

Query: 301 MNRGKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEKISKFFGK 360
           MNRGKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEKISKFFGK
Sbjct: 301 MNRGKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEKISKFFGK 360

Query: 361 ELSTTLNADEAVTRGCALQCAILSPAFKVREFSITDVVPYPISLRWNSPAEEGSSDCEVF 420
           ELSTTLNADEAVTRGCALQCAILSPAFKVREFSITDVVPYPISLRWNSPAEEGSSDCEVF
Sbjct: 361 ELSTTLNADEAVTRGCALQCAILSPAFKVREFSITDVVPYPISLRWNSPAEEGSSDCEVF 420

Query: 421 SKNHAAPFSKVLTFYRKEPFTLEAYYSSPQDLPYPDPAIAQFSVQKVTPQSDGSSSKVKV 480
           SKNHAAPFSKVLTFYRKEPFTLEAYYSSPQDLPYPDPAIAQFSVQKVTPQSDGSSSKVKV
Sbjct: 421 SKNHAAPFSKVLTFYRKEPFTLEAYYSSPQDLPYPDPAIAQFSVQKVTPQSDGSSSKVKV 480

Query: 481 KVRVNVHGIFSVSSASLVEVHKSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPA 540
           KVRVNVHGIFSVSSASLVEVHKSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPA
Sbjct: 481 KVRVNVHGIFSVSSASLVEVHKSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPA 540

Query: 541 ENKAESEEMETSQAGSKDKKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIEN 600
           ENKAESEEMETSQAGSKDKKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIEN
Sbjct: 541 ENKAESEEMETSQAGSKDKKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIEN 600

Query: 601 EGKMIMQDKLEKERNDAKNAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLY 660
           EGKMIMQDKLEKERNDAKNAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLY
Sbjct: 601 EGKMIMQDKLEKERNDAKNAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLY 660

Query: 661 EDGEDQPKQVYVDKLAELKNLGQPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKE 720
           EDGEDQPKQVYVDKLAELKNLGQPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKE
Sbjct: 661 EDGEDQPKQVYVDKLAELKNLGQPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKE 720

Query: 721 DQYDHLDAADMTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKELTSTCS 780
           DQYDHLDAADMTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKELTSTCS
Sbjct: 721 DQYDHLDAADMTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKELTSTCS 780

Query: 781 PIISKPKPKVEPPKEEQKNAEQNGPVDGQGDNPGPQAAEQGTDTAVPSDSDKKLPEMDID 840
           PIISKPKPKVEPPKEEQKNAEQNGPVDGQGDNPGPQAAEQGTDTAVPSDSDKKLPEMDID
Sbjct: 781 PIISKPKPKVEPPKEEQKNAEQNGPVDGQGDNPGPQAAEQGTDTAVPSDSDKKLPEMDID 840


>gi|31541941 heat shock 70kDa protein 4-like [Homo sapiens]
          Length = 839

 Score = 1088 bits (2813), Expect = 0.0
 Identities = 541/853 (63%), Positives = 669/853 (78%), Gaps = 27/853 (3%)

Query: 1   MSVVGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISNA 60
           MSVVGIDLGF +CY+AVAR+GGIETIANEYSDRCTPACIS G + R+IG AAKSQ+++N 
Sbjct: 1   MSVVGIDLGFLNCYIAVARSGGIETIANEYSDRCTPACISLGSRTRAIGNAAKSQIVTNV 60

Query: 61  KNTVQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTAM 120
           +NT+ GFK+ HGR+F DP V+ E+  L Y++ ++P G  G+KV Y+EEER F  EQVT M
Sbjct: 61  RNTIHGFKKLHGRSFDDPIVQTERIRLPYELQKMPNGSAGVKVRYLEEERPFAIEQVTGM 120

Query: 121 LLSKLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVALA 180
           LL+KLKET+E+ LKKPV DCV+S+P F+TDAERRSVM A Q+AGLNCLRLMNETTAVALA
Sbjct: 121 LLAKLKETSENALKKPVADCVISIPSFFTDAERRSVMAAAQVAGLNCLRLMNETTAVALA 180

Query: 181 YGIYKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVL 240
           YGIYKQDLP L+EKPRNVVF+DMGHSAYQV VCAFN+GKLKVLAT FD  LGGR FDE L
Sbjct: 181 YGIYKQDLPPLDEKPRNVVFIDMGHSAYQVLVCAFNKGKLKVLATTFDPYLGGRNFDEAL 240

Query: 241 VNHFCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMNDVDVSGT 300
           V++FC+EF  KYK+++K   RALLRL QECEKLKKLMSANASDLPL+IECFMND+DVS  
Sbjct: 241 VDYFCDEFKTKYKINVKENSRALLRLYQECEKLKKLMSANASDLPLNIECFMNDLDVSSK 300

Query: 301 MNRGKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEKISKFFGK 360
           MNR +F ++C  LLARVEPPL++V+EQ  L++EDI ++EIVGGATRIPAVKE+I+KFF K
Sbjct: 301 MNRAQFEQLCASLLARVEPPLKAVMEQANLQREDISSIEIVGGATRIPAVKEQITKFFLK 360

Query: 361 ELSTTLNADEAVTRGCALQCAILSPAFKVREFSITDVVPYPISLRWNSPAEEGSSDCEVF 420
           ++STTLNADEAV RGCALQCAILSPAFKVREFSITD+VPY I+LRW +  E+GS +CEVF
Sbjct: 361 DISTTLNADEAVARGCALQCAILSPAFKVREFSITDLVPYSITLRWKTSFEDGSGECEVF 420

Query: 421 SKNHAAPFSKVLTFYRKEPFTLEAYYSSPQDLPYPDPAIAQFSVQKVTPQSDGSSSKVKV 480
            KNH APFSKV+TF++KEPF LEA+Y++  ++PYPD  I  F++Q V PQSDG SSKVKV
Sbjct: 421 CKNHPAPFSKVITFHKKEPFELEAFYTNLHEVPYPDARIGSFTIQNVFPQSDGDSSKVKV 480

Query: 481 KVRVNVHGIFSVSSASLVEVH--KSEENEEPMETDQNAKEE-----EKMQVDQEEPHVEE 533
           KVRVN+HGIFSV+SAS++E    + + ++ PMET+ + K E     +KMQVDQEE H + 
Sbjct: 481 KVRVNIHGIFSVASASVIEKQNLEGDHSDAPMETETSFKNENKDNMDKMQVDQEEGHQKC 540

Query: 534 QQQQTPAENKAESEEMETSQAGSKDKKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREM 593
             + TP E    +     S    K  +++Q    KK KVK  ++DLPI++ L  Q+ +++
Sbjct: 541 HAEHTPEEEIDHTGAKTKSAVSDKQDRLNQ--TLKKGKVK--SIDLPIQSSLCRQLGQDL 596

Query: 594 LNLYIENEGKMIMQDKLEKERNDAKNAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLE 653
           LN YIENEGKMIMQDKLEKERNDAKNAVEEYVY+ RD+L   YEKF++ +D +  +  LE
Sbjct: 597 LNSYIENEGKMIMQDKLEKERNDAKNAVEEYVYDFRDRLGTVYEKFITPEDLSKLSAVLE 656

Query: 654 DTENWLYEDGEDQPKQVYVDKLAELKNLGQPIKIRFQESEERPKLFEELGKQIQQYMKII 713
           DTENWLYEDGEDQPKQVYVDKL ELK  GQPI++++ E EERPK   +LGK+IQ  MK+I
Sbjct: 657 DTENWLYEDGEDQPKQVYVDKLQELKKYGQPIQMKYMEHEERPKALNDLGKKIQLVMKVI 716

Query: 714 SSFKNKEDQYDHLDAADMTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIK 773
            +++NK+++YDHLD  +M KVEK  ++AM W+N+K+N QNK SLT DPVVK  EI AK K
Sbjct: 717 EAYRNKDERYDHLDPTEMEKVEKCISDAMSWLNSKMNAQNKLSLTQDPVVKVSEIVAKSK 776

Query: 774 ELTSTCSPIISKPKPKVEPPKEEQK-NAEQNGPVDGQGDNPGPQAAEQGTDTAVPSDSD- 831
           EL + C+PII KPKPK E P+++ K N+E NGP+DGQ           GT+T   S  D 
Sbjct: 777 ELDNFCNPIIYKPKPKAEVPEDKPKANSEHNGPMDGQ----------SGTETKSDSTKDS 826

Query: 832 ----KKLPEMDID 840
               K   EM++D
Sbjct: 827 SQHTKSSGEMEVD 839


>gi|42544159 heat shock 105kD [Homo sapiens]
          Length = 858

 Score = 1082 bits (2798), Expect = 0.0
 Identities = 539/822 (65%), Positives = 652/822 (79%), Gaps = 20/822 (2%)

Query: 1   MSVVGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISNA 60
           MSVVG+D+G QSCY+AVARAGGIETIANE+SDRCTP+ ISFG KNR+IG AAK+Q I++A
Sbjct: 1   MSVVGLDVGSQSCYIAVARAGGIETIANEFSDRCTPSVISFGSKNRTIGVAAKNQQITHA 60

Query: 61  KNTVQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTAM 120
            NTV  FKRFHGRAF+DPF++ EK NL+YD+V L  G  GIKV YM EE  F+ EQ+TAM
Sbjct: 61  NNTVSNFKRFHGRAFNDPFIQKEKENLSYDLVPLKNGGVGIKVMYMGEEHLFSVEQITAM 120

Query: 121 LLSKLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVALA 180
           LL+KLKETAE+ LKKPV DCV+SVP F+TDAERRSV+DA QI GLNCLRLMN+ TAVAL 
Sbjct: 121 LLTKLKETAENSLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMNDMTAVALN 180

Query: 181 YGIYKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVL 240
           YGIYKQDLP+L+EKPR VVFVDMGHSA+QVS CAFN+GKLKVL TAFD  LGG+ FDE L
Sbjct: 181 YGIYKQDLPSLDEKPRIVVFVDMGHSAFQVSACAFNKGKLKVLGTAFDPFLGGKNFDEKL 240

Query: 241 VNHFCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMNDVDVSGT 300
           V HFC EF  KYKLD KSKIRALLRL QECEKLKKLMS+N++DLPL+IECFMND DVSG 
Sbjct: 241 VEHFCAEFKTKYKLDAKSKIRALLRLYQECEKLKKLMSSNSTDLPLNIECFMNDKDVSGK 300

Query: 301 MNRGKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEKISKFFGK 360
           MNR +F E+C +LL ++E PL S+LEQT LK ED+ AVEIVGGATRIPAVKE+I+KFFGK
Sbjct: 301 MNRSQFEELCAELLQKIEVPLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAKFFGK 360

Query: 361 ELSTTLNADEAVTRGCALQCAILSPAFKVREFSITDVVPYPISLRWNSPAEEGSSDCEVF 420
           ++STTLNADEAV RGCALQCAILSPAFKVREFS+TD VP+PISL WN  +E+     EVF
Sbjct: 361 DISTTLNADEAVARGCALQCAILSPAFKVREFSVTDAVPFPISLIWNHDSEDTEGVHEVF 420

Query: 421 SKNHAAPFSKVLTFYRKEPFTLEAYYSSPQDLPYPDPAIAQFSVQKVTPQSDGSSSKVKV 480
           S+NHAAPFSKVLTF R+ PF LEA+YS PQ +PYP+  I +F VQ V+ Q DG  S+VKV
Sbjct: 421 SRNHAAPFSKVLTFLRRGPFELEAFYSDPQGVPYPEAKIGRFVVQNVSAQKDGEKSRVKV 480

Query: 481 KVRVNVHGIFSVSSASLVEVHKSEENEEPMETD---------QNAKEEEKMQVDQEE--- 528
           KVRVN HGIF++S+AS+VE   +EENE   E D         +N   ++ +Q D  E   
Sbjct: 481 KVRVNTHGIFTISTASMVEKVPTEENEMSSEADMECLNQRPPENPDTDKNVQQDNSEAGT 540

Query: 529 -PHVEEQQQQT---PAENKAESEEMETSQAG-SKDKKMDQPPQAKKAKVKTSTVDLPIEN 583
            P V+   QQT   P   +  SEE +   A  + +KK+DQPP+AKK K+K   V+LPIE 
Sbjct: 541 QPQVQTDAQQTSQSPPSPELTSEENKIPDADKANEKKVDQPPEAKKPKIKVVNVELPIEA 600

Query: 584 QLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAKNAVEEYVYEMRDKLSGEYEKFVSED 643
            L+WQ+ +++LN+YIE EGKMIMQDKLEKERNDAKNAVEEYVYE RDKL G YEKF+ E 
Sbjct: 601 NLVWQLGKDLLNMYIETEGKMIMQDKLEKERNDAKNAVEEYVYEFRDKLCGPYEKFICEQ 660

Query: 644 DRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKNLGQPIKIRFQESEERPKLFEELG 703
           D  +F   L +TE+WLYE+GEDQ KQ YVDKL EL  +G P+K+RFQE+EERPK+FEELG
Sbjct: 661 DHQNFLRLLTETEDWLYEEGEDQAKQAYVDKLEELMKIGTPVKVRFQEAEERPKMFEELG 720

Query: 704 KQIQQYMKIISSFKNKEDQYDHLDAADMTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVV 763
           +++Q Y KI + F+NK+++Y+H+D ++M KVEKS NE MEWMNN +N Q K+SL  DPVV
Sbjct: 721 QRLQHYAKIAADFRNKDEKYNHIDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLDQDPVV 780

Query: 764 KSKEIEAKIKELTSTCSPIISKPKPKVEPPKEEQKNAEQNGP 805
           +++EI+ KIKEL +TC P++++PKPK+E PK E+     NGP
Sbjct: 781 RAQEIKTKIKELNNTCEPVVTQPKPKIESPKLER---TPNGP 819


>gi|195976805 hypoxia up-regulated 1 precursor [Homo sapiens]
          Length = 999

 Score =  314 bits (805), Expect = 2e-85
 Identities = 257/939 (27%), Positives = 425/939 (45%), Gaps = 116/939 (12%)

Query: 1   MSVVGIDLGFQSCYVAVARAG-GIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISN 59
           ++V+ +DLG +S  VA+ + G  +E + N+ S R TP  ++     R  G +A S  I N
Sbjct: 33  LAVMSVDLGSESMKVAIVKPGVPMEIVLNKESRRKTPVIVTLKENERFFGDSAASMAIKN 92

Query: 60  AKNTVQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTA 119
            K T++ F+   G+   +P V   ++      +        +    +  +  F+ E+V  
Sbjct: 93  PKATLRYFQHLLGKQADNPHVALYQARFPEHELTFDPQRQTVHFQ-ISSQLQFSPEEVLG 151

Query: 120 MLLSKLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVAL 179
           M+L+  +  AE   ++P+ D V++VP F+  AERR+V+ A ++AGL  L+L+N+ TA AL
Sbjct: 152 MVLNYSRSLAEDFAEQPIKDAVITVPVFFNQAERRAVLQAARMAGLKVLQLINDNTATAL 211

Query: 180 AYGIYKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGK---------LKVLATAFDTT 230
           +YG++++    +    +N++F DMG  +   ++  +   K         L++    FD T
Sbjct: 212 SYGVFRR--KDINTTAQNIMFYDMGSGSTVCTIVTYQMVKTKEAGMQPQLQIRGVGFDRT 269

Query: 231 LGGRKFD----EVLVNHFCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPL 286
           LGG + +    E L   F E+   +   D++   RA+ +L +E  +LK ++SANA D   
Sbjct: 270 LGGLEMELRLRERLAGLFNEQRKGQRAKDVRENPRAMAKLLREANRLKTVLSANA-DHMA 328

Query: 287 SIECFMNDVDVSGTMNRGKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATR 346
            IE  M+DVD    + R +F E+C DL  RV  P++  L+  ++  ++I  V +VGGATR
Sbjct: 329 QIEGLMDDVDFKAKVTRVEFEELCADLFERVPGPVQQALQSAEMSLDEIEQVILVGGATR 388

Query: 347 IPAVKEKISKFFGK-ELSTTLNADEAVTRGCALQCAILSPAFKVREFSITDVVPYPISLR 405
           +P V+E + K  GK EL   +NADEA   G   Q A LS AFKV+ F + D V YPI + 
Sbjct: 389 VPRVQEVLLKAVGKEELGKNINADEAAAMGAVYQAAALSKAFKVKPFVVRDAVVYPILVE 448

Query: 406 WNSPAEE-------GSSDCEVFSKNHAAPFSKVLTFYR-KEPFTLEAYYSSPQDLPYPDP 457
           +    EE         +   +FS+    P  KV+TF R    F     Y    DL +  P
Sbjct: 449 FTREVEEEPGIHSLKHNKRVLFSRMGPYPQRKVITFNRYSHDFNFHINYG---DLGFLGP 505

Query: 458 A-IAQFSVQKVT------------PQSDGSSSKVKVKVRVNVHGIFSVSSA-----SLVE 499
             +  F  Q +T               D  S  +K    ++  G+ S+        +LVE
Sbjct: 506 EDLRVFGSQNLTTVKLKGVGDSFKKYPDYESKGIKAHFNLDESGVLSLDRVESVFETLVE 565

Query: 500 VHKSEEN------------------------------EEPMETDQNAKEEEKMQV---DQ 526
               EE+                              EE     + +K+E   QV   ++
Sbjct: 566 DSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDTVQEEEESPAEGSKDEPGEQVELKEE 625

Query: 527 EEPHVEEQQQQTPAENK----------AESEEMETSQAGSKDKKMD-------------- 562
            E  VE+  Q  P E K           E E  + S+A    +K +              
Sbjct: 626 AEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDKSEAQKPSEKAEAGPEGVAPAPEGEK 685

Query: 563 -QPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAKNAV 621
            Q P  K+  V+   V+L + +  L  +  + L   ++    + ++D  ++ER  A N++
Sbjct: 686 KQKPARKRRMVEEIGVELVVLD--LPDLPEDKLAQSVQKLQDLTLRDLEKQEREKAANSL 743

Query: 622 EEYVYEMRDKL-SGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKN 680
           E +++E +DKL   EY++  +E+ R   + KL     WL ++G      +  +KLAEL+ 
Sbjct: 744 EAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAASTWLEDEGVGATTVMLKEKLAELRK 803

Query: 681 LGQPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAADMTKVEKSTNE 740
           L Q +  R +E ++ P+    L   +      +   +   +        +MT +EK  NE
Sbjct: 804 LCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGARLIPEMDQIFTEVEMTTLEKVINE 863

Query: 741 AMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKELTSTCSPIISKPKPKVEPPKEEQKNA 800
              W N  L  Q K   T  PV+ SK+IEAK+  L      +++K K     P+ + KN 
Sbjct: 864 TWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDREVQYLLNKAKFTKPRPRPKDKNG 923

Query: 801 EQ-----NGPVDGQGDNPGPQAAEQGTDTAVPSDSDKKL 834
            +     N     QG+   P A +  T+ A P    +K+
Sbjct: 924 TRAEPPLNASASDQGEKVIPPAGQ--TEDAEPISEPEKV 960


>gi|5453832 hypoxia up-regulated 1 precursor [Homo sapiens]
          Length = 999

 Score =  314 bits (805), Expect = 2e-85
 Identities = 257/939 (27%), Positives = 425/939 (45%), Gaps = 116/939 (12%)

Query: 1   MSVVGIDLGFQSCYVAVARAG-GIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISN 59
           ++V+ +DLG +S  VA+ + G  +E + N+ S R TP  ++     R  G +A S  I N
Sbjct: 33  LAVMSVDLGSESMKVAIVKPGVPMEIVLNKESRRKTPVIVTLKENERFFGDSAASMAIKN 92

Query: 60  AKNTVQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTA 119
            K T++ F+   G+   +P V   ++      +        +    +  +  F+ E+V  
Sbjct: 93  PKATLRYFQHLLGKQADNPHVALYQARFPEHELTFDPQRQTVHFQ-ISSQLQFSPEEVLG 151

Query: 120 MLLSKLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVAL 179
           M+L+  +  AE   ++P+ D V++VP F+  AERR+V+ A ++AGL  L+L+N+ TA AL
Sbjct: 152 MVLNYSRSLAEDFAEQPIKDAVITVPVFFNQAERRAVLQAARMAGLKVLQLINDNTATAL 211

Query: 180 AYGIYKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGK---------LKVLATAFDTT 230
           +YG++++    +    +N++F DMG  +   ++  +   K         L++    FD T
Sbjct: 212 SYGVFRR--KDINTTAQNIMFYDMGSGSTVCTIVTYQMVKTKEAGMQPQLQIRGVGFDRT 269

Query: 231 LGGRKFD----EVLVNHFCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPL 286
           LGG + +    E L   F E+   +   D++   RA+ +L +E  +LK ++SANA D   
Sbjct: 270 LGGLEMELRLRERLAGLFNEQRKGQRAKDVRENPRAMAKLLREANRLKTVLSANA-DHMA 328

Query: 287 SIECFMNDVDVSGTMNRGKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATR 346
            IE  M+DVD    + R +F E+C DL  RV  P++  L+  ++  ++I  V +VGGATR
Sbjct: 329 QIEGLMDDVDFKAKVTRVEFEELCADLFERVPGPVQQALQSAEMSLDEIEQVILVGGATR 388

Query: 347 IPAVKEKISKFFGK-ELSTTLNADEAVTRGCALQCAILSPAFKVREFSITDVVPYPISLR 405
           +P V+E + K  GK EL   +NADEA   G   Q A LS AFKV+ F + D V YPI + 
Sbjct: 389 VPRVQEVLLKAVGKEELGKNINADEAAAMGAVYQAAALSKAFKVKPFVVRDAVVYPILVE 448

Query: 406 WNSPAEE-------GSSDCEVFSKNHAAPFSKVLTFYR-KEPFTLEAYYSSPQDLPYPDP 457
           +    EE         +   +FS+    P  KV+TF R    F     Y    DL +  P
Sbjct: 449 FTREVEEEPGIHSLKHNKRVLFSRMGPYPQRKVITFNRYSHDFNFHINYG---DLGFLGP 505

Query: 458 A-IAQFSVQKVT------------PQSDGSSSKVKVKVRVNVHGIFSVSSA-----SLVE 499
             +  F  Q +T               D  S  +K    ++  G+ S+        +LVE
Sbjct: 506 EDLRVFGSQNLTTVKLKGVGDSFKKYPDYESKGIKAHFNLDESGVLSLDRVESVFETLVE 565

Query: 500 VHKSEEN------------------------------EEPMETDQNAKEEEKMQV---DQ 526
               EE+                              EE     + +K+E   QV   ++
Sbjct: 566 DSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDTVQEEEESPAEGSKDEPGEQVELKEE 625

Query: 527 EEPHVEEQQQQTPAENK----------AESEEMETSQAGSKDKKMD-------------- 562
            E  VE+  Q  P E K           E E  + S+A    +K +              
Sbjct: 626 AEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDKSEAQKPSEKAEAGPEGVAPAPEGEK 685

Query: 563 -QPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAKNAV 621
            Q P  K+  V+   V+L + +  L  +  + L   ++    + ++D  ++ER  A N++
Sbjct: 686 KQKPARKRRMVEEIGVELVVLD--LPDLPEDKLAQSVQKLQDLTLRDLEKQEREKAANSL 743

Query: 622 EEYVYEMRDKL-SGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKN 680
           E +++E +DKL   EY++  +E+ R   + KL     WL ++G      +  +KLAEL+ 
Sbjct: 744 EAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAASTWLEDEGVGATTVMLKEKLAELRK 803

Query: 681 LGQPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAADMTKVEKSTNE 740
           L Q +  R +E ++ P+    L   +      +   +   +        +MT +EK  NE
Sbjct: 804 LCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGARLIPEMDQIFTEVEMTTLEKVINE 863

Query: 741 AMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKELTSTCSPIISKPKPKVEPPKEEQKNA 800
              W N  L  Q K   T  PV+ SK+IEAK+  L      +++K K     P+ + KN 
Sbjct: 864 TWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDREVQYLLNKAKFTKPRPRPKDKNG 923

Query: 801 EQ-----NGPVDGQGDNPGPQAAEQGTDTAVPSDSDKKL 834
            +     N     QG+   P A +  T+ A P    +K+
Sbjct: 924 TRAEPPLNASASDQGEKVIPPAGQ--TEDAEPISEPEKV 960


>gi|34419635 heat shock 70kDa protein 6 (HSP70B') [Homo sapiens]
          Length = 643

 Score =  301 bits (770), Expect = 2e-81
 Identities = 191/581 (32%), Positives = 310/581 (53%), Gaps = 27/581 (4%)

Query: 4   VGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISNAKNT 63
           VGIDLG     V V + G +E +AN+  +R TP+ ++F    R +G AAKSQ   N  NT
Sbjct: 9   VGIDLGTTYSCVGVFQQGRVEILANDQGNRTTPSYVAFTDTERLVGDAAKSQAALNPHNT 68

Query: 64  VQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTAMLLS 123
           V   KR  GR F+D  V+++  +  + +V    G   ++V Y  E++ F  E++++M+LS
Sbjct: 69  VFDAKRLIGRKFADTTVQSDMKHWPFRVVS-EGGKPKVRVCYRGEDKTFYPEEISSMVLS 127

Query: 124 KLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVALAYGI 183
           K+KETAE+ L +PV   V++VP ++ D++R++  DA  IAGLN LR++NE TA A+AYG+
Sbjct: 128 KMKETAEAYLGQPVKHAVITVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGL 187

Query: 184 YKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVLVNH 243
            ++         RNV+  D+G   + VSV + + G  +V ATA DT LGG  FD  LVNH
Sbjct: 188 DRRG-----AGERNVLIFDLGGGTFDVSVLSIDAGVFEVKATAGDTHLGGEDFDNRLVNH 242

Query: 244 FCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMNDVDVSGTMNR 303
           F EEF +K+  D+    RAL RL   CE+ K+ +S +++   L I+     VD   ++ R
Sbjct: 243 FMEEFRRKHGKDLSGNKRALRRLRTACERAKRTLS-SSTQATLEIDSLFEGVDFYTSITR 301

Query: 304 GKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEKISKFF-GKEL 362
            +F E+C+DL      P+   L   KL K  I+ V +VGG+TRIP V++ +  FF GKEL
Sbjct: 302 ARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDVVLVGGSTRIPKVQKLLQDFFNGKEL 361

Query: 363 STTLNADEAVTRGCALQCAIL--SPAFKVREFSITDVVPYPISLRWNSPAEEGSSDCEVF 420
           + ++N DEAV  G A+Q A+L      KV++  + DV P  + L        G     + 
Sbjct: 362 NKSINPDEAVAYGAAVQAAVLMGDKCEKVQDLLLLDVAPLSLGLE-----TAGGVMTTLI 416

Query: 421 SKNHAAPFSKVLTFYR---KEPFTLEAYYSSPQDLPYPDPAIAQFSVQKVTPQSDGSSSK 477
            +N   P  +  TF      +P      Y   + +   +  + +F +  + P   G   +
Sbjct: 417 QRNATIPTKQTQTFTTYSDNQPGVFIQVYEGERAMTKDNNLLGRFELSGIPPAPRG-VPQ 475

Query: 478 VKVKVRVNVHGIFSVSSASLVEVHKSEENEEPMETDQN--AKEEEKMQVDQEEPHV---E 532
           ++V   ++ +GI SV++    +    + N+  +  D+   +KEE +  V + E +    E
Sbjct: 476 IEVTFDIDANGILSVTA---TDRSTGKANKITITNDKGRLSKEEVERMVHEAEQYKAEDE 532

Query: 533 EQQQQTPAENKAESEEMETSQAGSKDKKMDQPPQAKKAKVK 573
            Q+ +  A+N  E+       +  ++   D+ P+  + K++
Sbjct: 533 AQRDRVAAKNSLEAHVFHVKGSLQEESLRDKIPEEDRRKMQ 573


>gi|167466173 heat shock 70kDa protein 1B [Homo sapiens]
          Length = 641

 Score =  294 bits (752), Expect = 3e-79
 Identities = 188/582 (32%), Positives = 309/582 (53%), Gaps = 27/582 (4%)

Query: 2   SVVGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISNAK 61
           + +GIDLG     V V + G +E IAN+  +R TP+ ++F    R IG AAK+QV  N +
Sbjct: 5   AAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQ 64

Query: 62  NTVQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTAML 121
           NTV   KR  GR F DP V+++  +  + ++        ++V+Y  E + F  E++++M+
Sbjct: 65  NTVFDAKRLIGRKFGDPVVQSDMKHWPFQVIN-DGDKPKVQVSYKGETKAFYPEEISSMV 123

Query: 122 LSKLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVALAY 181
           L+K+KE AE+ L  PV + V++VP ++ D++R++  DA  IAGLN LR++NE TA A+AY
Sbjct: 124 LTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAY 183

Query: 182 GIYKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVLV 241
           G     L    +  RNV+  D+G   + VS+   + G  +V ATA DT LGG  FD  LV
Sbjct: 184 G-----LDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLV 238

Query: 242 NHFCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMNDVDVSGTM 301
           NHF EEF +K+K DI    RA+ RL   CE+ K+ +S +++   L I+     +D   ++
Sbjct: 239 NHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLS-SSTQASLEIDSLFEGIDFYTSI 297

Query: 302 NRGKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEKISKFF-GK 360
            R +F E+C+DL      P+   L   KL K  I+ + +VGG+TRIP V++ +  FF G+
Sbjct: 298 TRARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGR 357

Query: 361 ELSTTLNADEAVTRGCALQCAIL--SPAFKVREFSITDVVPYPISLRWNSPAEEGSSDCE 418
           +L+ ++N DEAV  G A+Q AIL    +  V++  + DV P  + L        G     
Sbjct: 358 DLNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLE-----TAGGVMTA 412

Query: 419 VFSKNHAAPFSKV---LTFYRKEPFTLEAYYSSPQDLPYPDPAIAQFSVQKVTPQSDGSS 475
           +  +N   P  +     T+   +P  L   Y   + +   +  + +F +  + P   G  
Sbjct: 413 LIKRNSTIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPRG-V 471

Query: 476 SKVKVKVRVNVHGIFSVSSASLVEVHKSEENEEPMETDQN--AKEEEKMQVDQEEPHVEE 533
            +++V   ++ +GI +V++    +    + N+  +  D+   +KEE +  V + E +  E
Sbjct: 472 PQIEVTFDIDANGILNVTA---TDKSTGKANKITITNDKGRLSKEEIERMVQEAEKYKAE 528

Query: 534 ---QQQQTPAENKAESEEMETSQAGSKDKKMDQPPQAKKAKV 572
              Q+++  A+N  ES       A   +    +  +A K KV
Sbjct: 529 DEVQRERVSAKNALESYAFNMKSAVEDEGLKGKISEADKKKV 570



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 26/99 (26%), Positives = 50/99 (50%), Gaps = 2/99 (2%)

Query: 588 QIDREMLNLYIENEGKMIMQDKLEKERNDAKNAVEEYVYEMRDKLSGEYEK-FVSEDDRN 646
           ++ +E +   ++   K   +D++++ER  AKNA+E Y + M+  +  E  K  +SE D+ 
Sbjct: 509 RLSKEEIERMVQEAEKYKAEDEVQRERVSAKNALESYAFNMKSAVEDEGLKGKISEADKK 568

Query: 647 SFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKNLGQPI 685
               K ++  +WL +      K  +  K  EL+ +  PI
Sbjct: 569 KVLDKCQEVISWL-DANTLAEKDEFEHKRKELEQVCNPI 606



 Score = 31.6 bits (70), Expect = 3.2
 Identities = 31/133 (23%), Positives = 49/133 (36%), Gaps = 21/133 (15%)

Query: 688 RFQESEERPKLFEELGKQ-------IQQYMKIISSFKNKEDQYDHLDAADMTKVEKSTNE 740
           R  +  E+ K  +E+ ++       ++ Y   + S    E     +  AD  KV     E
Sbjct: 517 RMVQEAEKYKAEDEVQRERVSAKNALESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQE 576

Query: 741 AMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKELTSTCSPIISKPKPKVEPPKEEQKNA 800
            + W++             + + +  E E K KEL   C+PIIS        P      A
Sbjct: 577 VISWLD------------ANTLAEKDEFEHKRKELEQVCNPIISGLYQGAGGPGPGGFGA 624

Query: 801 EQNGPVDGQGDNP 813
           +  GP  G G  P
Sbjct: 625 Q--GPKGGSGSGP 635


>gi|194248072 heat shock 70kDa protein 1A [Homo sapiens]
          Length = 641

 Score =  294 bits (752), Expect = 3e-79
 Identities = 188/582 (32%), Positives = 309/582 (53%), Gaps = 27/582 (4%)

Query: 2   SVVGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISNAK 61
           + +GIDLG     V V + G +E IAN+  +R TP+ ++F    R IG AAK+QV  N +
Sbjct: 5   AAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQ 64

Query: 62  NTVQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTAML 121
           NTV   KR  GR F DP V+++  +  + ++        ++V+Y  E + F  E++++M+
Sbjct: 65  NTVFDAKRLIGRKFGDPVVQSDMKHWPFQVIN-DGDKPKVQVSYKGETKAFYPEEISSMV 123

Query: 122 LSKLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVALAY 181
           L+K+KE AE+ L  PV + V++VP ++ D++R++  DA  IAGLN LR++NE TA A+AY
Sbjct: 124 LTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAY 183

Query: 182 GIYKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVLV 241
           G     L    +  RNV+  D+G   + VS+   + G  +V ATA DT LGG  FD  LV
Sbjct: 184 G-----LDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLV 238

Query: 242 NHFCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMNDVDVSGTM 301
           NHF EEF +K+K DI    RA+ RL   CE+ K+ +S +++   L I+     +D   ++
Sbjct: 239 NHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLS-SSTQASLEIDSLFEGIDFYTSI 297

Query: 302 NRGKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEKISKFF-GK 360
            R +F E+C+DL      P+   L   KL K  I+ + +VGG+TRIP V++ +  FF G+
Sbjct: 298 TRARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGR 357

Query: 361 ELSTTLNADEAVTRGCALQCAIL--SPAFKVREFSITDVVPYPISLRWNSPAEEGSSDCE 418
           +L+ ++N DEAV  G A+Q AIL    +  V++  + DV P  + L        G     
Sbjct: 358 DLNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLE-----TAGGVMTA 412

Query: 419 VFSKNHAAPFSKV---LTFYRKEPFTLEAYYSSPQDLPYPDPAIAQFSVQKVTPQSDGSS 475
           +  +N   P  +     T+   +P  L   Y   + +   +  + +F +  + P   G  
Sbjct: 413 LIKRNSTIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPRG-V 471

Query: 476 SKVKVKVRVNVHGIFSVSSASLVEVHKSEENEEPMETDQN--AKEEEKMQVDQEEPHVEE 533
            +++V   ++ +GI +V++    +    + N+  +  D+   +KEE +  V + E +  E
Sbjct: 472 PQIEVTFDIDANGILNVTA---TDKSTGKANKITITNDKGRLSKEEIERMVQEAEKYKAE 528

Query: 534 ---QQQQTPAENKAESEEMETSQAGSKDKKMDQPPQAKKAKV 572
              Q+++  A+N  ES       A   +    +  +A K KV
Sbjct: 529 DEVQRERVSAKNALESYAFNMKSAVEDEGLKGKISEADKKKV 570



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 26/99 (26%), Positives = 50/99 (50%), Gaps = 2/99 (2%)

Query: 588 QIDREMLNLYIENEGKMIMQDKLEKERNDAKNAVEEYVYEMRDKLSGEYEK-FVSEDDRN 646
           ++ +E +   ++   K   +D++++ER  AKNA+E Y + M+  +  E  K  +SE D+ 
Sbjct: 509 RLSKEEIERMVQEAEKYKAEDEVQRERVSAKNALESYAFNMKSAVEDEGLKGKISEADKK 568

Query: 647 SFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKNLGQPI 685
               K ++  +WL +      K  +  K  EL+ +  PI
Sbjct: 569 KVLDKCQEVISWL-DANTLAEKDEFEHKRKELEQVCNPI 606



 Score = 31.6 bits (70), Expect = 3.2
 Identities = 31/133 (23%), Positives = 49/133 (36%), Gaps = 21/133 (15%)

Query: 688 RFQESEERPKLFEELGKQ-------IQQYMKIISSFKNKEDQYDHLDAADMTKVEKSTNE 740
           R  +  E+ K  +E+ ++       ++ Y   + S    E     +  AD  KV     E
Sbjct: 517 RMVQEAEKYKAEDEVQRERVSAKNALESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQE 576

Query: 741 AMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKELTSTCSPIISKPKPKVEPPKEEQKNA 800
            + W++             + + +  E E K KEL   C+PIIS        P      A
Sbjct: 577 VISWLD------------ANTLAEKDEFEHKRKELEQVCNPIISGLYQGAGGPGPGGFGA 624

Query: 801 EQNGPVDGQGDNP 813
           +  GP  G G  P
Sbjct: 625 Q--GPKGGSGSGP 635


>gi|124256496 heat shock 70kDa protein 1-like [Homo sapiens]
          Length = 641

 Score =  293 bits (749), Expect = 6e-79
 Identities = 189/580 (32%), Positives = 312/580 (53%), Gaps = 27/580 (4%)

Query: 4   VGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISNAKNT 63
           +GIDLG     V V + G +E IAN+  +R TP+ ++F    R IG AAK+QV  N +NT
Sbjct: 9   IGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPQNT 68

Query: 64  VQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTAMLLS 123
           V   KR  GR F+DP V+A+     + ++    G   + V+Y  E + F  E++++M+L+
Sbjct: 69  VFDAKRLIGRKFNDPVVQADMKLWPFQVIN-EGGKPKVLVSYKGENKAFYPEEISSMVLT 127

Query: 124 KLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVALAYGI 183
           KLKETAE+ L  PV + V++VP ++ D++R++  DA  IAGLN LR++NE TA A+AYG+
Sbjct: 128 KLKETAEAFLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGL 187

Query: 184 YKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVLVNH 243
            K       +  R+V+  D+G   + VS+   + G  +V ATA DT LGG  FD  LV+H
Sbjct: 188 DKGG-----QGERHVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVSH 242

Query: 244 FCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMNDVDVSGTMNR 303
           F EEF +K+K DI    RA+ RL   CE+ K+ +S +++   L I+     +D   ++ R
Sbjct: 243 FVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLS-SSTQANLEIDSLYEGIDFYTSITR 301

Query: 304 GKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEKISKFF-GKEL 362
            +F E+C DL      P+   L   K+ K  I+ + +VGG+TRIP V+  +  +F G++L
Sbjct: 302 ARFEELCADLFRGTLEPVEKALRDAKMDKAKIHDIVLVGGSTRIPKVQRLLQDYFNGRDL 361

Query: 363 STTLNADEAVTRGCALQCAIL--SPAFKVREFSITDVVPYPISLRWNSPAEEGSSDCEVF 420
           + ++N DEAV  G A+Q AIL    + KV++  + DV P  + L        G     + 
Sbjct: 362 NKSINPDEAVAYGAAVQAAILMGDKSEKVQDLLLLDVAPLSLGLE-----TAGGVMTALI 416

Query: 421 SKNHAAPFSKV---LTFYRKEPFTLEAYYSSPQDLPYPDPAIAQFSVQKVTPQSDGSSSK 477
            +N   P  +     T+   +P  L   Y   + +   +  + +F +  + P   G   +
Sbjct: 417 KRNSTIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFDLTGIPPAPRG-VPQ 475

Query: 478 VKVKVRVNVHGIFSVSSASLVEVHKSEENEEPMETDQN--AKEE-EKMQVDQEEPHVEE- 533
           ++V   ++ +GI +V++    +    + N+  +  D+   +KEE E+M +D E+   E+ 
Sbjct: 476 IEVTFDIDANGILNVTA---TDKSTGKVNKITITNDKGRLSKEEIERMVLDAEKYKAEDE 532

Query: 534 -QQQQTPAENKAESEEMETSQAGSKDKKMDQPPQAKKAKV 572
            Q+++  A+N  ES         S +    +  ++ K K+
Sbjct: 533 VQREKIAAKNALESYAFNMKSVVSDEGLKGKISESDKNKI 572



 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 28/99 (28%), Positives = 52/99 (52%), Gaps = 2/99 (2%)

Query: 588 QIDREMLNLYIENEGKMIMQDKLEKERNDAKNAVEEYVYEMRDKLSGEYEK-FVSEDDRN 646
           ++ +E +   + +  K   +D++++E+  AKNA+E Y + M+  +S E  K  +SE D+N
Sbjct: 511 RLSKEEIERMVLDAEKYKAEDEVQREKIAAKNALESYAFNMKSVVSDEGLKGKISESDKN 570

Query: 647 SFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKNLGQPI 685
               K  +  +WL E  +   K  +  K  EL+ +  PI
Sbjct: 571 KILDKCNELLSWL-EVNQLAEKDEFDHKRKELEQMCNPI 608



 Score = 32.3 bits (72), Expect = 1.9
 Identities = 22/100 (22%), Positives = 43/100 (43%), Gaps = 14/100 (14%)

Query: 686 KIRFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAADMTKVEKSTNEAMEWM 745
           K + ++  +R K+  +    ++ Y   + S  + E     +  +D  K+    NE + W 
Sbjct: 526 KYKAEDEVQREKIAAK--NALESYAFNMKSVVSDEGLKGKISESDKNKILDKCNELLSW- 582

Query: 746 NNKLNLQNKQSLTMDPVVKSKEIEAKIKELTSTCSPIISK 785
                      L ++ + +  E + K KEL   C+PII+K
Sbjct: 583 -----------LEVNQLAEKDEFDHKRKELEQMCNPIITK 611


>gi|5729877 heat shock 70kDa protein 8 isoform 1 [Homo sapiens]
          Length = 646

 Score =  288 bits (738), Expect = 1e-77
 Identities = 199/623 (31%), Positives = 322/623 (51%), Gaps = 36/623 (5%)

Query: 4   VGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISNAKNT 63
           VGIDLG     V V + G +E IAN+  +R TP+ ++F    R IG AAK+QV  N  NT
Sbjct: 7   VGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNT 66

Query: 64  VQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTAMLLS 123
           V   KR  GR F D  V+++  +  + +V    G   ++V Y  E ++F  E+V++M+L+
Sbjct: 67  VFDAKRLIGRRFDDAVVQSDMKHWPFMVVN-DAGRPKVQVEYKGETKSFYPEEVSSMVLT 125

Query: 124 KLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVALAYGI 183
           K+KE AE+ L K V + VV+VP ++ D++R++  DA  IAGLN LR++NE TA A+AYG+
Sbjct: 126 KMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGL 185

Query: 184 YKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVLVNH 243
            K+         RNV+  D+G   + VS+     G  +V +TA DT LGG  FD  +VNH
Sbjct: 186 DKK-----VGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNH 240

Query: 244 FCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMNDVDVSGTMNR 303
           F  EF +K+K DI    RA+ RL   CE+ K+ +S +++   + I+     +D   ++ R
Sbjct: 241 FIAEFKRKHKKDISENKRAVRRLRTACERAKRTLS-SSTQASIEIDSLYEGIDFYTSITR 299

Query: 304 GKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEKISKFF-GKEL 362
            +F E+  DL      P+   L   KL K  I+ + +VGG+TRIP +++ +  FF GKEL
Sbjct: 300 ARFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKEL 359

Query: 363 STTLNADEAVTRGCALQCAILS--PAFKVREFSITDVVPYPISLRWNSPAEEGSSDCEVF 420
           + ++N DEAV  G A+Q AILS   +  V++  + DV P  + +        G     + 
Sbjct: 360 NKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIE-----TAGGVMTVLI 414

Query: 421 SKNHAAPFSKVLTFYR---KEPFTLEAYYSSPQDLPYPDPAIAQFSVQKVTPQSDGSSSK 477
            +N   P  +  TF      +P  L   Y   + +   +  + +F +  + P   G   +
Sbjct: 415 KRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRG-VPQ 473

Query: 478 VKVKVRVNVHGIFSVSSASLVEVHKSEENEEPMETDQN--AKEEEKMQVDQEEPHV---E 532
           ++V   ++ +GI +VS+   V+    +EN+  +  D+   +KE+ +  V + E +    E
Sbjct: 474 IEVTFDIDANGILNVSA---VDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDE 530

Query: 533 EQQQQTPAENKAESEEMETSQAGSKDKKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDRE 592
           +Q+ +  ++N  ES           +K   +     K K+      L   N+++  +D+ 
Sbjct: 531 KQRDKVSSKNSLESYAFNMKATVEDEKLQGKINDEDKQKI------LDKCNEIINWLDK- 583

Query: 593 MLNLYIENEGKMIMQDKLEKERN 615
             N   E E     Q +LEK  N
Sbjct: 584 --NQTAEKEEFEHQQKELEKVCN 604



 Score = 39.3 bits (90), Expect = 0.015
 Identities = 22/110 (20%), Positives = 56/110 (50%), Gaps = 10/110 (9%)

Query: 588 QIDREMLNLYIENEGKMIMQDKLEKERNDAKNAVEEYVYEMR-----DKLSGEYEKFVSE 642
           ++ +E +   ++   K   +D+ ++++  +KN++E Y + M+     +KL G+    +++
Sbjct: 509 RLSKEDIERMVQEAEKYKAEDEKQRDKVSSKNSLESYAFNMKATVEDEKLQGK----IND 564

Query: 643 DDRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKNLGQPIKIRFQES 692
           +D+     K  +  NWL +  +   K+ +  +  EL+ +  PI  +  +S
Sbjct: 565 EDKQKILDKCNEIINWL-DKNQTAEKEEFEHQQKELEKVCNPIITKLYQS 613



 Score = 31.6 bits (70), Expect = 3.2
 Identities = 25/118 (21%), Positives = 50/118 (42%), Gaps = 12/118 (10%)

Query: 679 KNLGQPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAADMTKVEKST 738
           K+ G+  KI     + R    E++ + +Q+  K  +  + + D+    ++ +        
Sbjct: 493 KSTGKENKITITNDKGRLSK-EDIERMVQEAEKYKAEDEKQRDKVSSKNSLESYAFNMKA 551

Query: 739 NEAMEWMNNKLNLQNKQS-----------LTMDPVVKSKEIEAKIKELTSTCSPIISK 785
               E +  K+N ++KQ            L  +   + +E E + KEL   C+PII+K
Sbjct: 552 TVEDEKLQGKINDEDKQKILDKCNEIINWLDKNQTAEKEEFEHQQKELEKVCNPIITK 609


>gi|16507237 heat shock 70kDa protein 5 [Homo sapiens]
          Length = 654

 Score =  284 bits (727), Expect = 2e-76
 Identities = 194/603 (32%), Positives = 316/603 (52%), Gaps = 44/603 (7%)

Query: 2   SVVGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISFGPKN-RSIGAAAKSQVISNA 60
           +VVGIDLG     V V + G +E IAN+  +R TP+ ++F P+  R IG AAK+Q+ SN 
Sbjct: 29  TVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNP 88

Query: 61  KNTVQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYME------EERNFTT 114
           +NTV   KR  GR ++DP V+ +   L + +V+  T        Y++      + + F  
Sbjct: 89  ENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTK------PYIQVDIGGGQTKTFAP 142

Query: 115 EQVTAMLLSKLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNET 174
           E+++AM+L+K+KETAE+ L K V   VV+VP ++ DA+R++  DA  IAGLN +R++NE 
Sbjct: 143 EEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEP 202

Query: 175 TAVALAYGIYKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGR 234
           TA A+AYG+ K+      E  +N++  D+G   + VS+   + G  +V+AT  DT LGG 
Sbjct: 203 TAAAIAYGLDKR------EGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGE 256

Query: 235 KFDEVLVNHFCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMND 294
            FD+ ++ HF + + KK   D++   RA+ +L +E EK K+ +S+      + IE F   
Sbjct: 257 DFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQ-HQARIEIESFYEG 315

Query: 295 VDVSGTMNRGKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEKI 354
            D S T+ R KF E+  DL      P++ VLE + LKK DI  + +VGG+TRIP +++ +
Sbjct: 316 EDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLV 375

Query: 355 SKFF-GKELSTTLNADEAVTRGCALQCAILSPAFKVREFSITDVVPYPISLRWNSPAEEG 413
            +FF GKE S  +N DEAV  G A+Q  +LS      +  + DV P  + +        G
Sbjct: 376 KEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVCPLTLGIE-----TVG 430

Query: 414 SSDCEVFSKNHAAPFSKVLTFYR---KEPFTLEAYYSSPQDLPYPDPAIAQFSVQKVTPQ 470
               ++  +N   P  K   F      +P      Y   + L   +  +  F +  + P 
Sbjct: 431 GVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPA 490

Query: 471 SDGSSSKVKVKVRVNVHGIFSVSSASLVEVHKSEENEEPMETDQN---AKEEEKMQVDQE 527
             G   +++V   ++V+GI  V++    +     +N+  +  DQN    +E E+M  D E
Sbjct: 491 PRG-VPQIEVTFEIDVNGILRVTAE---DKGTGNKNKITITNDQNRLTPEEIERMVNDAE 546

Query: 528 EPHVEEQQQQTPAENKAESEEMETS---QAGSKDKKMDQPPQAKKAKVKTSTVDLPIENQ 584
           +   E+++ +   + + E E    S   Q G K+K        K +     T++  +E +
Sbjct: 547 KFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKL-----GGKLSSEDKETMEKAVEEK 601

Query: 585 LLW 587
           + W
Sbjct: 602 IEW 604



 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 32/113 (28%), Positives = 56/113 (49%), Gaps = 5/113 (4%)

Query: 592 EMLNLYIENEGKMIMQDKLEKERNDAKNAVEEYVYEMRDKLSGEYEKF---VSEDDRNSF 648
           E +   + +  K   +DK  KER D +N +E Y Y +++++ G+ EK    +S +D+ + 
Sbjct: 536 EEIERMVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQI-GDKEKLGGKLSSEDKETM 594

Query: 649 TLKLEDTENWLYEDGEDQPKQVYVDKLAELKNLGQPIKIRFQESEERPKLFEE 701
              +E+   WL E  +D   + +  K  EL+ + QPI  +   S   P   EE
Sbjct: 595 EKAVEEKIEWL-ESHQDADIEDFKAKKKELEEIVQPIISKLYGSAGPPPTGEE 646



 Score = 35.4 bits (80), Expect = 0.22
 Identities = 30/118 (25%), Positives = 54/118 (45%), Gaps = 14/118 (11%)

Query: 688 RFQESEERPKLFEELGKQIQQYM-KIISSFKNKEDQYDHLDAADMTKVEKSTNEAMEWMN 746
           +F E +++ K   +   +++ Y   + +   +KE     L + D   +EK+  E +EW  
Sbjct: 547 KFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEEKIEW-- 604

Query: 747 NKLNLQNKQSLTMDPVVKSKEIEAKIKELTSTCSPIISKPKPKV-EPPKEEQKNAEQN 803
               L++ Q   ++      + +AK KEL     PIISK       PP  E+  AE++
Sbjct: 605 ----LESHQDADIE------DFKAKKKELEEIVQPIISKLYGSAGPPPTGEEDTAEKD 652


>gi|13676857 heat shock 70kDa protein 2 [Homo sapiens]
          Length = 639

 Score =  271 bits (692), Expect = 2e-72
 Identities = 179/580 (30%), Positives = 298/580 (51%), Gaps = 25/580 (4%)

Query: 4   VGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISNAKNT 63
           +GIDLG     V V + G +E IAN+  +R TP+ ++F    R IG AAK+QV  N  NT
Sbjct: 8   IGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNT 67

Query: 64  VQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTAMLLS 123
           +   KR  GR F D  V+++  +  + +V    G   ++V Y  E + F  E++++M+L+
Sbjct: 68  IFDAKRLIGRKFEDATVQSDMKHWPFRVVS-EGGKPKVQVEYKGETKTFFPEEISSMVLT 126

Query: 124 KLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVALAYGI 183
           K+KE AE+ L   V   V++VP ++ D++R++  DA  I GLN LR++NE TA A+AYG+
Sbjct: 127 KMKEIAEAYLGGKVHSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAAAIAYGL 186

Query: 184 YKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVLVNH 243
            K+     E   +NV+  D+G   + VS+     G  +V +TA DT LGG  FD  +V+H
Sbjct: 187 DKKGCAGGE---KNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVSH 243

Query: 244 FCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMNDVDVSGTMNR 303
             EEF +K+K DI    RA+ RL   CE+ K+ +S +++   + I+     VD   ++ R
Sbjct: 244 LAEEFKRKHKKDIGPNKRAVRRLRTACERAKRTLS-SSTQASIEIDSLYEGVDFYTSITR 302

Query: 304 GKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEKISKFF-GKEL 362
            +F E+  DL      P+   L   KL K  I  + +VGG+TRIP +++ +  FF GKEL
Sbjct: 303 ARFEELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGKEL 362

Query: 363 STTLNADEAVTRGCALQCAIL--SPAFKVREFSITDVVPYPISLRWNSPAEEGSSDCEVF 420
           + ++N DEAV  G A+Q AIL    +  V++  + DV P  + +        G     + 
Sbjct: 363 NKSINPDEAVAYGAAVQAAILIGDKSENVQDLLLLDVTPLSLGIE-----TAGGVMTPLI 417

Query: 421 SKNHAAPFSKVLTFYR---KEPFTLEAYYSSPQDLPYPDPAIAQFSVQKVTPQSDGSSSK 477
            +N   P  +  TF      +   L   Y   + +   +  + +F +  + P   G   +
Sbjct: 418 KRNTTIPTKQTQTFTTYSDNQSSVLVQVYEGERAMTKDNNLLGKFDLTGIPPAPRG-VPQ 476

Query: 478 VKVKVRVNVHGIFSVSSASLVEVHKSEENEEPMETDQN--AKEEEKMQVDQEEPHVEEQQ 535
           ++V   ++ +GI +V++A   +    +EN+  +  D+   +K++    V + E +  E +
Sbjct: 477 IEVTFDIDANGILNVTAA---DKSTGKENKITITNDKGRLSKDDIDRMVQEAERYKSEDE 533

Query: 536 ---QQTPAENKAESEEMETSQAGSKDKKMDQPPQAKKAKV 572
               +  A+N  ES      Q    +K   +  +  K K+
Sbjct: 534 ANRDRVAAKNALESYTYNIKQTVEDEKLRGKISEQDKNKI 573



 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 25/99 (25%), Positives = 50/99 (50%), Gaps = 2/99 (2%)

Query: 588 QIDREMLNLYIENEGKMIMQDKLEKERNDAKNAVEEYVYEMRDKLSGE-YEKFVSEDDRN 646
           ++ ++ ++  ++   +   +D+  ++R  AKNA+E Y Y ++  +  E     +SE D+N
Sbjct: 512 RLSKDDIDRMVQEAERYKSEDEANRDRVAAKNALESYTYNIKQTVEDEKLRGKISEQDKN 571

Query: 647 SFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKNLGQPI 685
               K ++  NWL +  +   K  Y  K  EL+ +  PI
Sbjct: 572 KILDKCQEVINWL-DRNQMAEKDEYEHKQKELERVCNPI 609


>gi|24234686 heat shock 70kDa protein 8 isoform 2 [Homo sapiens]
          Length = 493

 Score =  270 bits (689), Expect = 5e-72
 Identities = 161/434 (37%), Positives = 244/434 (56%), Gaps = 15/434 (3%)

Query: 4   VGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISNAKNT 63
           VGIDLG     V V + G +E IAN+  +R TP+ ++F    R IG AAK+QV  N  NT
Sbjct: 7   VGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNT 66

Query: 64  VQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTAMLLS 123
           V   KR  GR F D  V+++  +  + +V    G   ++V Y  E ++F  E+V++M+L+
Sbjct: 67  VFDAKRLIGRRFDDAVVQSDMKHWPFMVVN-DAGRPKVQVEYKGETKSFYPEEVSSMVLT 125

Query: 124 KLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVALAYGI 183
           K+KE AE+ L K V + VV+VP ++ D++R++  DA  IAGLN LR++NE TA A+AYG+
Sbjct: 126 KMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGL 185

Query: 184 YKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVLVNH 243
            K+         RNV+  D+G   + VS+     G  +V +TA DT LGG  FD  +VNH
Sbjct: 186 DKK-----VGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNH 240

Query: 244 FCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMNDVDVSGTMNR 303
           F  EF +K+K DI    RA+ RL   CE+ K+ +S +++   + I+     +D   ++ R
Sbjct: 241 FIAEFKRKHKKDISENKRAVRRLRTACERAKRTLS-SSTQASIEIDSLYEGIDFYTSITR 299

Query: 304 GKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEKISKFF-GKEL 362
            +F E+  DL      P+   L   KL K  I+ + +VGG+TRIP +++ +  FF GKEL
Sbjct: 300 ARFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKEL 359

Query: 363 STTLNADEAVTRGCALQCAILS--PAFKVREFSITDVVPYPISLRWNSPAEEGSSDCEVF 420
           + ++N DEAV  G A+Q AILS   +  V++  + DV P  + +        G     + 
Sbjct: 360 NKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIE-----TAGGVMTVLI 414

Query: 421 SKNHAAPFSKVLTF 434
            +N   P  +  TF
Sbjct: 415 KRNTTIPTKQTQTF 428


>gi|24234688 heat shock 70kDa protein 9 precursor [Homo sapiens]
          Length = 679

 Score =  219 bits (558), Expect = 8e-57
 Identities = 158/573 (27%), Positives = 277/573 (48%), Gaps = 39/573 (6%)

Query: 2   SVVGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISF-GPKNRSIGAAAKSQVISNA 60
           +VVGIDLG  +  VAV      + + N    R TP+ ++F     R +G  AK Q ++N 
Sbjct: 54  AVVGIDLGTTNSCVAVMEGKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQAVTNP 113

Query: 61  KNTVQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTAM 120
            NT    KR  GR + DP V+ +  N+ + IV+   G   ++       + ++  Q+ A 
Sbjct: 114 NNTFYATKRLIGRRYDDPEVQKDIKNVPFKIVRASNGDAWVEA----HGKLYSPSQIGAF 169

Query: 121 LLSKLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVALA 180
           +L K+KETAE+ L     + V++VP ++ D++R++  DA QI+GLN LR++NE TA ALA
Sbjct: 170 VLMKMKETAENYLGHTAKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAAALA 229

Query: 181 YGIYKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVL 240
           YG+ K +        + +   D+G   + +S+    +G  +V +T  DT LGG  FD+ L
Sbjct: 230 YGLDKSE-------DKVIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTFLGGEDFDQAL 282

Query: 241 VNHFCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANAS---DLPLSIECFMNDVDV 297
           + H  +EF ++  +D+     AL R+ +  EK K  +S++     +LP           +
Sbjct: 283 LRHIVKEFKRETGVDLTKDNMALQRVREAAEKAKCELSSSVQTDINLPYLTMDSSGPKHL 342

Query: 298 SGTMNRGKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEKISKF 357
           +  + R +F  +  DL+ R   P +  ++  ++ K DI  V +VGG TR+P V++ +   
Sbjct: 343 NMKLTRAQFEGIVTDLIRRTIAPCQKAMQDAEVSKSDIGEVILVGGMTRMPKVQQTVQDL 402

Query: 358 FGKELSTTLNADEAVTRGCALQCAILSPAFKVREFSITDVVPYPISLRWNSPAEEGSSDC 417
           FG+  S  +N DEAV  G A+Q  +L  A  V +  + DV P  + +        G    
Sbjct: 403 FGRAPSKAVNPDEAVAIGAAIQGGVL--AGDVTDVLLLDVTPLSLGIE-----TLGGVFT 455

Query: 418 EVFSKNHAAPFSKVLTFYRKEPFTLEA---YYSSPQDLPYPDPAIAQFSVQKVTPQSDGS 474
           ++ ++N   P  K   F        +         +++   +  + QF++  + P   G 
Sbjct: 456 KLINRNTTIPTKKSQVFSTAADGQTQVEIKVCQGEREMAGDNKLLGQFTLIGIPPAPRG- 514

Query: 475 SSKVKVKVRVNVHGIFSVSSASLVEVHKSEENEEPMETDQN---AKEEEKMQVDQEEPHV 531
             +++V   ++ +GI  VS+       K    E+ +    +   +K++ +  V   E + 
Sbjct: 515 VPQIEVTFDIDANGIVHVSAKD-----KGTGREQQIVIQSSGGLSKDDIENMVKNAEKYA 569

Query: 532 EE---QQQQTPAENKAES--EEMETSQAGSKDK 559
           EE   ++++  A N AE    + ET     KD+
Sbjct: 570 EEDRRKKERVEAVNMAEGIIHDTETKMEEFKDQ 602


>gi|82880658 heat shock 70kDa protein 14 isoform 1 [Homo sapiens]
          Length = 509

 Score =  191 bits (485), Expect = 2e-48
 Identities = 123/391 (31%), Positives = 200/391 (51%), Gaps = 21/391 (5%)

Query: 1   MSVVGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISNA 60
           M+ +G+ LG  S  VAV + G    +AN+  DR TPA +++      +G AAK   I N 
Sbjct: 1   MAAIGVHLGCTSACVAVYKDGRAGVVANDAGDRVTPAVVAYSENEEIVGLAAKQSRIRNI 60

Query: 61  KNTVQGFKRFHGRAFSDPFVE---AEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQV 117
            NTV   K+  GR+ SDP  +   AE   L  +      G    ++   EE +    E V
Sbjct: 61  SNTVMKVKQILGRSSSDPQAQKYIAESKCLVIE----KNGKLRYEIDTGEETKFVNPEDV 116

Query: 118 TAMLLSKLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAV 177
             ++ SK+KETA SVL     D V++VP  + + ++ ++ +A + AG N LRL++E +A 
Sbjct: 117 ARLIFSKMKETAHSVLGSDANDVVITVPFDFGEKQKNALGEAARAAGFNVLRLIHEPSAA 176

Query: 178 ALAYGIYKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGRKFD 237
            LAYGI  QD P  +    N++   +G ++  +SV   N G  +VL+T  D  +GG  F 
Sbjct: 177 LLAYGI-GQDSPTGKS---NILVFKLGGTSLSLSVMEVNSGIYRVLSTNTDDNIGGAHFT 232

Query: 238 EVLVNHFCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMNDV-- 295
           E L  +   EF + +K D++   RA+++L+   E  K  +S        S  CF++ +  
Sbjct: 233 ETLAQYLASEFQRSFKHDVRGNARAMMKLTNSAEVAKHSLSTLG-----SANCFLDSLYE 287

Query: 296 --DVSGTMNRGKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEK 353
             D    ++R +F  +C+ L  +    +R +L+Q     +DI  V + GG++RIP +++ 
Sbjct: 288 GQDFDCNVSRARFELLCSPLFNKCIEAIRGLLDQNGFTADDINKVVLCGGSSRIPKLQQL 347

Query: 354 ISKFF-GKELSTTLNADEAVTRGCALQCAIL 383
           I   F   EL  ++  DE +  G A++  IL
Sbjct: 348 IKDLFPAVELLNSIPPDEVIPIGAAIEAGIL 378


>gi|48928056 heat shock protein 70kDa family member 13 precursor
           [Homo sapiens]
          Length = 471

 Score =  163 bits (412), Expect = 7e-40
 Identities = 124/424 (29%), Positives = 204/424 (48%), Gaps = 54/424 (12%)

Query: 3   VVGIDLGFQSCYVAV--ARAGGIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISNA 60
           V+GIDLG   C V V     G ++ I +E      P+ +SF   +  +G  +     SN 
Sbjct: 33  VIGIDLGTTYCSVGVFFPGTGKVKVIPDENGHISIPSMVSFTDNDVYVGYESVELADSNP 92

Query: 61  KNTVQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTAM 120
           +NT+   KRF G+ F+   +EAE     + ++    G+    VT   E    + E V + 
Sbjct: 93  QNTIYDAKRFIGKIFTAEELEAEIGRYPFKVLN-KNGMVEFSVT-SNETITVSPEYVGSR 150

Query: 121 LLSKLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVALA 180
           LL KLKE AE+ L  PV + V+SVP  +   +R S ++A  +AGL  LR++NE TA A+A
Sbjct: 151 LLLKLKEMAEAYLGMPVANAVISVPAEFDLKQRNSTIEAANLAGLKILRVINEPTAAAMA 210

Query: 181 YGIYKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVL 240
           YG++K D+        +V+ +D+G     VS+     G     A + +  LGG+ F++ L
Sbjct: 211 YGLHKADV-------FHVLVIDLGGGTLDVSLLNKQGGMFLTRAMSGNNKLGGQDFNQRL 263

Query: 241 VNHFCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANAS------------------ 282
           + +  ++  + Y   + S+   + RL Q  E +K  ++ + S                  
Sbjct: 264 LQYLYKQIYQTYGF-VPSRKEEIHRLRQAVEMVKLNLTLHQSAQLSVLLTVEEQDRKEPH 322

Query: 283 ----DLPLSIECFMNDVDVSGTMNRG-------------------KFLEMCN-DLLARVE 318
               +LP       +D  V+    RG                   K  +  N DL  ++ 
Sbjct: 323 SSDTELPKDKLSSADDHRVNSGFGRGLSDKKSGESQVLFETEISRKLFDTLNEDLFQKIL 382

Query: 319 PPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEKISKFFGKELSTTLNADEAVTRGCAL 378
            P++ VL++  L+K +I  V +VGG+TRIP +++ I +FFGK+ +T+++ D AV  G A+
Sbjct: 383 VPIQQVLKEGHLEKTEIDEVVLVGGSTRIPRIRQVIQEFFGKDPNTSVDPDLAVVTGVAI 442

Query: 379 QCAI 382
           Q  I
Sbjct: 443 QAGI 446


>gi|221219020 NYD-SP11 protein [Homo sapiens]
          Length = 2873

 Score = 59.7 bits (143), Expect = 1e-08
 Identities = 70/292 (23%), Positives = 129/292 (44%), Gaps = 40/292 (13%)

Query: 492  VSSASLVEVHKSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQ-------QQQTPAENKA 544
            +SS S  + +K EE     E      EE++ QV +E+ H++E+       +++  AE K 
Sbjct: 1529 LSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKR 1588

Query: 545  ESEEMETSQAGSKDKKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKM 604
              EE + +Q   K  + ++    ++ K+  + V +        Q DREM     + EGK 
Sbjct: 1589 AQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKIT-------QDDREM----AQAEGKF 1637

Query: 605  IMQDKLEKERNDAKNAVEEYVYEMRDKLSGEYEKFVSEDDRNSFT-LKLEDTENWLYEDG 663
              +++   +R +  +   E + + R KL+ ++EK   E+++ +    KL + +N L +  
Sbjct: 1638 AQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKV 1697

Query: 664  EDQPKQVYVDKLAELKNLGQPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQY 723
            E+ P++         +NL    K   QE EE     EEL            S+K +E   
Sbjct: 1698 EELPQRE--------QNLDWQEKELAQELEELEWDMEEL------------SWKEEELNQ 1737

Query: 724  DHLDAADMTKVEKSTNEAMEWMNNKLN-LQNKQSLTMDPVVKSKEIEAKIKE 774
            +     +  K      EA+ W   KL+  + K +   + +++ KE  A+ KE
Sbjct: 1738 EEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKE 1789



 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 33/146 (22%), Positives = 70/146 (47%), Gaps = 3/146 (2%)

Query: 499  EVHKSEENE---EPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAG 555
            E H SEE E   + +E  ++   EE+ + ++EE   EE+ ++   E K E E  E     
Sbjct: 2223 EEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEK 2282

Query: 556  SKDKKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERN 615
             +++K  +  + KK +V+        + +++ + + E L+   E E    +++++++E+ 
Sbjct: 2283 EEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKE 2342

Query: 616  DAKNAVEEYVYEMRDKLSGEYEKFVS 641
              K   +  + E R K     E+ +S
Sbjct: 2343 ILKKEKQFKLQEQRRKSLRGRERVLS 2368



 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 36/154 (23%), Positives = 77/154 (50%), Gaps = 8/154 (5%)

Query: 494  SASLVEVHKSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQ 553
            S+ + EV   E   E ME+  +  E+++    +EE   EE++++   E + E EE +  +
Sbjct: 2214 SSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEE 2273

Query: 554  AGSKDKKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKE 613
             G ++K++++  + KK K K    +   E + +++   E+++   E E + +  ++ E+E
Sbjct: 2274 EG-EEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMS---EEETESLSDEEEEEE 2329

Query: 614  RNDAKNAVEEYVYEMRDKLSGEYEKFVSEDDRNS 647
                  ++EE V   ++ L  E +  + E  R S
Sbjct: 2330 ----SCSLEEEVDREKEILKKEKQFKLQEQRRKS 2359



 Score = 35.4 bits (80), Expect = 0.22
 Identities = 59/293 (20%), Positives = 128/293 (43%), Gaps = 29/293 (9%)

Query: 499  EVHKSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKD 558
            E  K  E EE +   +    EE+ ++ QEE  +  Q+++  A++K +  E E      ++
Sbjct: 1745 EKKKLAEEEEALAWQREKLSEEETKLAQEE-ELLIQEKEKLAQHKEKMPEEEERLGRKRE 1803

Query: 559  KKMDQPPQ--AKKAKVKTSTVDLPIENQLLWQ---IDREMLNLYIENEGKMIMQDKL--- 610
            + +++  +   K+ +   S  +L     +L+Q   + +E  NL  E E     ++ L   
Sbjct: 1804 QLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYN 1863

Query: 611  -------EKERNDAKNAV---EEYVYEMRDKLSGEYEKFVSEDDRNSFT-LKLEDTENWL 659
                   +K+    KN +    + + ++ +KL+ E E  + + ++ + T  KL   E+ L
Sbjct: 1864 KERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSL 1923

Query: 660  YEDGEDQPKQVYVDKLAELKNLGQ---PIKIRFQESEERPKLFEELGKQIQQYMKIISSF 716
             +  E   ++    KLA  K + Q    ++     ++E   L  E+ +  ++ M+++   
Sbjct: 1924 AKKQEKLAQEKM--KLALEKAMVQGKKRLRGELDIAKEEKALNLEMKRLAEEKMRLVEG- 1980

Query: 717  KNKEDQYDHLDAADMTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIE 769
               ++     +  + ++  K T    E    KL+L+ K  L  D ++  +E E
Sbjct: 1981 ---KETLSKGETPETSRQRKMTQVEQELFERKLSLEEKILLHEDRILAMEESE 2030


>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
           member 6-like protein 6 [Homo sapiens]
          Length = 655

 Score = 59.7 bits (143), Expect = 1e-08
 Identities = 52/275 (18%), Positives = 126/275 (45%), Gaps = 16/275 (5%)

Query: 502 KSEENEEPM-ETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKK 560
           K +E EE M E +   +E+E+    QEE   E++++    E+K   +E +  +   K ++
Sbjct: 305 KIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIRE 364

Query: 561 MDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAKNA 620
            ++    ++ K++     +  + + +W+ + ++     + + KM  Q+K  +E+++    
Sbjct: 365 QEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIRE 424

Query: 621 VEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKN 680
            EE ++   +K+  E E+ + + +      KL + E  + E+ E         K+ E + 
Sbjct: 425 QEEEMWRQEEKIR-ELEEMMQDQEE-----KLREVEEKMQEEEE---------KMQEQEE 469

Query: 681 LGQPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAADMTKVEKSTNE 740
             Q  + + QE EE+    E+L KQ ++  +       +E++    +     + EK   +
Sbjct: 470 KIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQ 529

Query: 741 AMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKEL 775
             +    ++ L  ++    +  V+ +E+E ++ +L
Sbjct: 530 EEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKL 564


>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
           member 6-like protein 6 [Homo sapiens]
          Length = 655

 Score = 59.7 bits (143), Expect = 1e-08
 Identities = 52/275 (18%), Positives = 126/275 (45%), Gaps = 16/275 (5%)

Query: 502 KSEENEEPM-ETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKK 560
           K +E EE M E +   +E+E+    QEE   E++++    E+K   +E +  +   K ++
Sbjct: 305 KIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIRE 364

Query: 561 MDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAKNA 620
            ++    ++ K++     +  + + +W+ + ++     + + KM  Q+K  +E+++    
Sbjct: 365 QEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIRE 424

Query: 621 VEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKN 680
            EE ++   +K+  E E+ + + +      KL + E  + E+ E         K+ E + 
Sbjct: 425 QEEEMWRQEEKIR-ELEEMMQDQEE-----KLREVEEKMQEEEE---------KMQEQEE 469

Query: 681 LGQPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAADMTKVEKSTNE 740
             Q  + + QE EE+    E+L KQ ++  +       +E++    +     + EK   +
Sbjct: 470 KIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQ 529

Query: 741 AMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKEL 775
             +    ++ L  ++    +  V+ +E+E ++ +L
Sbjct: 530 EEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKL 564


>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 828

 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 47/195 (24%), Positives = 90/195 (46%), Gaps = 9/195 (4%)

Query: 499 EVHKSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKD 558
           E  K  + EE M  ++  +E+EK   DQEE   EE++ +   +   E EEM   Q   K 
Sbjct: 525 EQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQE-EKM 583

Query: 559 KKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAK 618
           ++ ++  + ++ K+      +  + + +W+ + +M     E E KM  Q+++  E+ +  
Sbjct: 584 QEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQ--EEEDKMQEQEEMMWEQEEKM 641

Query: 619 NAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLAEL 678
              EE ++E  +K+  + EK   +++      K++  E  + E  E    Q    +  E 
Sbjct: 642 QEQEEKMWEQEEKMREQEEKMREQEE------KMQGQEEKMREQEEKMQGQEEKMREQEE 695

Query: 679 KNLGQPIKIRFQESE 693
           K  GQ  K+  QE +
Sbjct: 696 KMRGQEEKMWGQEEK 710



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 64/330 (19%), Positives = 147/330 (44%), Gaps = 33/330 (10%)

Query: 502 KSEENEEPM--------ETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQ 553
           K  E EE M        E ++  +E+EK   +Q++   +E+Q Q   E   E EE    Q
Sbjct: 270 KMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQ 329

Query: 554 AGSKDKKMDQPPQAKKAKVKTSTVDLPIENQLLWQID----------REMLNLYIENEGK 603
              K  + ++    ++ +++     +  + + +W+ D          RE   ++ E E K
Sbjct: 330 E-EKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMW-EQEEK 387

Query: 604 MIMQDKLEKERNDAKNAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTEN--WLYE 661
           M  ++++ +ER       EE + E  +K+  + E    ++++     +L + +   W  E
Sbjct: 388 MQEEERI-REREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQE 446

Query: 662 DGEDQPKQVY--VDKLAELKNL-GQPIKIRFQES--EERPKLFEELGKQIQQYMKIISSF 716
             ++Q ++++   +K+ + + + GQ  K+  QE   E+  +++E+  K   Q  K+    
Sbjct: 447 KMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQE 506

Query: 717 KNKEDQYDHL-DAADMTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKEL 775
           +   +Q + L +  +  + +K   +  E M  +   Q ++  T D   K +E E +++E 
Sbjct: 507 ERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMRE-EERMRER 565

Query: 776 TSTC---SPIISKPKPKVEPPKEEQKNAEQ 802
                    ++ + + K++  +E+ +  E+
Sbjct: 566 EKKMREEEEMMREQEEKMQEQEEKMREQEE 595



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 65/327 (19%), Positives = 145/327 (44%), Gaps = 24/327 (7%)

Query: 504 EENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKKMDQ 563
           E++E   E ++  +E+EKM   +E+   EE+ ++   + + E E M   +   + ++ + 
Sbjct: 363 EQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENM 422

Query: 564 PPQAKKAKVKTSTVDLPIENQLLWQIDR--EMLNLYIENEGKMIMQDKL---EKE--RND 616
             Q +K   +     LP + + LW+ ++  E      E E K+  Q+++   EK+  R +
Sbjct: 423 WEQEEK---EWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQE 479

Query: 617 AKNAVEEYVYEMRDKLSGEYEKFVSEDDRN-SFTLKLEDTENWLYE-----DGEDQPKQV 670
                E+ ++E  +K+  + +K   +++R      +L + E  + E       E++ ++ 
Sbjct: 480 KMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREE 539

Query: 671 YVDKLAELKNLGQPIKI----RFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHL 726
              +  E K   Q  K+    R +E E++ +  EE+ ++ ++ M+       ++++    
Sbjct: 540 KKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWE 599

Query: 727 DAADMTKVEKSTNEAMEWM---NNKLNLQNKQSLTMDPVVKSKEIEAKIKELTSTCSPII 783
               M + E+   E  E M     +  +Q ++ +  +   K +E E K+ E         
Sbjct: 600 QEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQE 659

Query: 784 SKPKPKVEPPK-EEQKNAEQNGPVDGQ 809
            K + + E  + +E+K  EQ   + GQ
Sbjct: 660 EKMREQEEKMQGQEEKMREQEEKMQGQ 686



 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 61/325 (18%), Positives = 139/325 (42%), Gaps = 22/325 (6%)

Query: 497 LVEVHKSEENEEPMETDQNAKEEEKMQVDQEEP--HVEEQQQQTPAENKAESEEMETSQA 554
           L +V  +   EE    ++  +E+EK    QEE     EE+ ++   + + + E+M   + 
Sbjct: 224 LPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEK 283

Query: 555 GSKDKKMDQPPQAK----KAKVKTSTVDLPIENQLLWQID---REMLNLYIENEGKMIMQ 607
             ++++ +   Q K    + K++     +  + + +W+ +   RE        E ++  Q
Sbjct: 284 RLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQ 343

Query: 608 DKLEKERNDAKNAVEEYVYEMRDKL------SGEYEKFVSEDDRNSFTLKLEDTENWLYE 661
           +K  +E+       EE ++E  ++L        E EK   ++++     ++ + E  + E
Sbjct: 344 EKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMRE 403

Query: 662 DGEDQPKQVYVDKLAELKNLGQPIKIRFQES---EERPKLFEELGKQIQQYMKIISSFKN 718
           + E   +Q    +  E +N+ +  +  +Q+    E++ KL+E+  K  +Q  KI    + 
Sbjct: 404 EEETMREQEEKMQKQE-ENMWEQEEKEWQQQRLPEQKEKLWEQ-EKMQEQEEKIWEQEEK 461

Query: 719 KEDQYDHL-DAADMTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKELTS 777
             DQ +       M + EK   +  +    +  +++++    D   +  E + +++E   
Sbjct: 462 IRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEE 521

Query: 778 TCSPIISKPKPKVEPPKEEQKNAEQ 802
                  K   + E  +EE+K  EQ
Sbjct: 522 RMRE-QKKMWQQEEKMREEKKTQEQ 545



 Score = 43.5 bits (101), Expect = 8e-04
 Identities = 27/132 (20%), Positives = 65/132 (49%), Gaps = 1/132 (0%)

Query: 502 KSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKKM 561
           + EE ++  E ++   E+E+   +QEE   E++++    E K   +E +      K ++ 
Sbjct: 620 EQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQ 679

Query: 562 DQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAKNAV 621
           ++  Q ++ K++     +  + + +W  + +M     +  G+  M++K E+ R D K  +
Sbjct: 680 EEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIR-DQKEKM 738

Query: 622 EEYVYEMRDKLS 633
           +E + E  ++ S
Sbjct: 739 QERLPEHEERCS 750


>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 899

 Score = 58.2 bits (139), Expect = 3e-08
 Identities = 60/290 (20%), Positives = 131/290 (45%), Gaps = 20/290 (6%)

Query: 499 EVHKSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKD 558
           E  K  E  E M  ++  +E+EK   DQEE  ++E+++    E K   EE    +   K 
Sbjct: 415 EQEKMWEQVEKMREEKKMQEQEKKTRDQEE-KMQEEERIREREKKMREEEETMREQEEKM 473

Query: 559 KKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDR--EMLNLYIENEGKMIMQDKL---EKE 613
           +K ++    ++ K +     LP + + LW+ ++  E      E E K+  Q+++   EK+
Sbjct: 474 QKQEENMWEQEEK-EWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKK 532

Query: 614 --RNDAKNAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYED--GEDQPKQ 669
             R +     E+ ++E  +K+  + +K   +++R     + ++ + W  E+   E++  +
Sbjct: 533 MWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMR 592

Query: 670 VYVDKLAELKNLGQPIKIRFQESEER-----PKLFEELGKQIQQYMKIISSFKNKEDQYD 724
               K+ E + + +  + + QE EE+      K++E+  K  +Q  K+    +   +Q +
Sbjct: 593 EREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEE 652

Query: 725 HLDAADMTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKE 774
            +        +K       W + K+  Q K     + + + +++E K +E
Sbjct: 653 KMWEQQRLPEQKE----KLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQE 698



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 55/235 (23%), Positives = 106/235 (45%), Gaps = 25/235 (10%)

Query: 502 KSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKKM 561
           K  E E   E ++  +EEE+M  +QEE   E++++    E K   +E +  +   K  + 
Sbjct: 584 KMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQ 643

Query: 562 DQPPQAKKAKVKTSTVDLPIENQLLWQIDR-EMLNLYIENEGKMIMQDKLEKERN----- 615
           ++    ++ K+      LP + + LW+ ++ +      E E K+  Q+K+EK+       
Sbjct: 644 EEKMWEQEEKM-WEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKK 702

Query: 616 --DAKNAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVD 673
             D +   EE     R+K   E E+ + E +      K+++ E  + E  E+  +Q    
Sbjct: 703 TWDQEKMREEESMREREKKMREEEEMMREQEE-----KMQEQEEKMQEQEEEMWEQ---- 753

Query: 674 KLAELKNLGQPIKIRFQE--SEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHL 726
              E K   Q  K+  Q+   E++ KL+E   +++Q+  KI    +   DQ + +
Sbjct: 754 ---EEKMWEQEEKMWEQQRLPEQKEKLWEH--EKMQEQEKIWEQEEKMRDQEEKM 803



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 51/223 (22%), Positives = 98/223 (43%), Gaps = 28/223 (12%)

Query: 497 LVEVHKSEENEEPMETDQNAKEEEKMQV----------DQEEPHVEEQQQQTPAENKAES 546
           L E  K +E E+  E ++   E+EKM+           DQE+   EE  ++   + + E 
Sbjct: 667 LWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEE 726

Query: 547 E---EMETSQAGSKDKKMDQPPQAKKAKVKTSTVD--------LPIENQLLWQIDREMLN 595
           E   E E      ++K  +Q  +  + + K    +        LP + + LW+ ++    
Sbjct: 727 EMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQ 786

Query: 596 LYI-ENEGKMIMQDKLEKERNDAKNAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLED 654
             I E E KM  Q++  + + +     EE +    +K+ G+ EK   ++++    +  ++
Sbjct: 787 EKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEK----MWGQE 842

Query: 655 TENWLYEDGEDQPKQVYVDKLAEL--KNLGQPIKIRFQESEER 695
            + W  E+  ++  Q   +K+ E   K  GQ  K+R QE + R
Sbjct: 843 EKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMR 885



 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 54/300 (18%), Positives = 137/300 (45%), Gaps = 16/300 (5%)

Query: 505 ENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKKMDQP 564
           E +E  E ++  +E+E+   +QEE   E++++    E +   +E +  +   K +  ++ 
Sbjct: 339 EQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEER 398

Query: 565 PQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAKNAVEEY 624
              +  +++     +  + ++  Q+++      +  E KM  Q+K  +++ + K   EE 
Sbjct: 399 MWEQDERLREKEERMREQEKMWEQVEK------MREEKKMQEQEKKTRDQEE-KMQEEER 451

Query: 625 VYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQV--YVDKLAELKNLG 682
           + E   K+  E E    ++++    ++ ++   W  E+ E Q +++    +KL E + + 
Sbjct: 452 IREREKKMREEEETMREQEEK----MQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKM- 506

Query: 683 QPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAADMTKVEKSTNEAM 742
           Q  + +  E EE+ +  EE+  Q ++ M      + +EDQ    +   M   E+   +  
Sbjct: 507 QEQEEKIWEQEEKIRDQEEMWGQ-EKKMWRQEKMREQEDQMWEQE-EKMRDQEQKMWDQE 564

Query: 743 EWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKELTSTCSPIISKPKPKVEPPKEEQKNAEQ 802
           E M  K   Q K++   +  ++ +E   + ++       ++ + + K++  +E+ +  E+
Sbjct: 565 ERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEE 624



 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 52/284 (18%), Positives = 128/284 (45%), Gaps = 17/284 (5%)

Query: 499 EVHKSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKD 558
           E    E+ E+  E ++  +E+E+    QEE   E+++Q    E K   +E    +   +D
Sbjct: 347 EEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQE---ERMWEQD 403

Query: 559 KKMDQPPQAKKAKVKT-STVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDA 617
           +++ +  +  + + K    V+   E + + + +++      + E KM  ++++ +ER   
Sbjct: 404 ERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTR----DQEEKMQEEERI-REREKK 458

Query: 618 KNAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTEN--WLYEDGEDQPKQVY--VD 673
               EE + E  +K+  + E    ++++     +L + +   W  E  ++Q ++++   +
Sbjct: 459 MREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEE 518

Query: 674 KLAELKNL-GQPIKIRFQES--EERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAAD 730
           K+ + + + GQ  K+  QE   E+  +++E+  K   Q  K+    +  E +    +   
Sbjct: 519 KIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKT 578

Query: 731 MTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKE 774
             + EK   E       +  ++ ++ +  +   K +E E K++E
Sbjct: 579 WDQEEKMREEE-RMREREKKMREEEEMMREQEEKMQEQEEKMQE 621



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 60/319 (18%), Positives = 141/319 (44%), Gaps = 41/319 (12%)

Query: 464 VQKVTPQSDGSSSKVKVKVRVNVHGIFSVSSASLVEVHKSEENEEPMETDQNAKEEEKMQ 523
           +Q+  P ++   S++++ V+  +      +   L +V  +   EE    ++  +E+EK  
Sbjct: 230 LQEKLPLAESEKSEIQLNVK-ELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKI 288

Query: 524 VDQEEP--HVEEQQQQTPAENKAESEEMETSQAGSKDKKMDQPPQAKKAK----VKTSTV 577
             QEE     EE+ ++   + + + E+M   +   ++++ +   Q K+ +    ++    
Sbjct: 289 RKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEE 348

Query: 578 DLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAKNAVEEYVYEMRDKLSGEYE 637
            +  + + +W+ + +M     E E KM  Q++   E+       E+ + E   K+  + E
Sbjct: 349 QMQEQEEKMWEQEEKMR----EQEEKMWRQEERLWEQ-------EKQMREQEQKMRDQEE 397

Query: 638 KFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKNLGQPIKIRFQESEERPK 697
           +   +D+R      L + E  +    E +     V+K+ E K + +  K + ++ EE+ +
Sbjct: 398 RMWEQDER------LREKEERM---REQEKMWEQVEKMREEKKMQEQEK-KTRDQEEKMQ 447

Query: 698 LFEELGKQIQQYMKIISSFKNKEDQYDHLDAADMTKVEKS--TNEAMEWMNNKLNLQNKQ 755
             E + ++ ++  +   + + +E++        M K E++    E  EW   +L  Q ++
Sbjct: 448 EEERIREREKKMREEEETMREQEEK--------MQKQEENMWEQEEKEWQQQRLPEQKEK 499

Query: 756 SLTMDPVVKSKEIEAKIKE 774
               +   K +E E KI E
Sbjct: 500 LWEQE---KMQEQEEKIWE 515


>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
          Length = 793

 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 54/295 (18%), Positives = 128/295 (43%), Gaps = 16/295 (5%)

Query: 491 SVSSASLVEVHKSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEME 550
           +++ ASL    +  +N+     ++  ++EEK +  QE   +EE +  T +  K +  + E
Sbjct: 124 TITDASLSLPSRRMQNDTA--ENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAE 181

Query: 551 TSQAGSKDKKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKL 610
            ++   K+K+ ++  + K+  +  + V++ +E +   +   E + + ++N      + K 
Sbjct: 182 ENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTT-ESQEETVVMSLKNGQISSEEPKQ 240

Query: 611 EKERNDAKNAVEEY-VYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQ 669
           E+ER    + +  +   E  DK   E E+   E +     +K E  +    E    + ++
Sbjct: 241 EEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERE-RIKAEQDKKIADERARIEAEE 299

Query: 670 VYVDKLAELKNLGQPIKIRFQE---SEERPKLFEELGKQIQQYMKIISSFKN-------- 718
               +  E +   +  ++R +E   +EER ++ EE  +  ++  +I    K         
Sbjct: 300 KAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRI 359

Query: 719 KEDQYDHLDAADMTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIK 773
           KE++    +     + E+     +E       L+ K+    +  +K +++E KI+
Sbjct: 360 KEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIE 414



 Score = 32.7 bits (73), Expect = 1.4
 Identities = 56/317 (17%), Positives = 121/317 (38%), Gaps = 70/317 (22%)

Query: 502 KSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKKM 561
           + ++  + +E  ++A +E K++ ++ E  +E +      E KA+ ++++T+    + ++ 
Sbjct: 384 EEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVN---EKKAQEDKLQTAVLKKQGEEK 440

Query: 562 DQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAKNAV 621
               QAK+ K++        E                      I  +K++K++       
Sbjct: 441 GTKVQAKREKLQEDKPTFKKEE---------------------IKDEKIKKDKEP----- 474

Query: 622 EEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKNL 681
           +E V    D+  G  E  V   +    T KL+ TEN                        
Sbjct: 475 KEEVKSFMDRKKGFTE--VKSQNGEFMTHKLKHTEN-------------------TFSRP 513

Query: 682 GQPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAADMTKVEKSTNEA 741
           G    +  +E+E  P++  E GK++++  +          +    ++ +  K+++   EA
Sbjct: 514 GGRASVDTKEAEGAPQV--EAGKRLEELRR----------RRGETESEEFEKLKQKQQEA 561

Query: 742 ---MEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKELTSTCSPIISKPKPKVEPPKEEQK 798
              +E +  K   + K     +   K +E + K++E          + K ++E  + E  
Sbjct: 562 ALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEK-----RRLKEEIERRRAEAA 616

Query: 799 NAEQNGPVDGQGDNPGP 815
              Q  P DG  D+  P
Sbjct: 617 EKRQKMPEDGLSDDKKP 633


>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 668

 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 47/236 (19%), Positives = 111/236 (47%), Gaps = 27/236 (11%)

Query: 499 EVHKSEENEEPMETDQNAKEEEKMQVDQEEPHVEE-----QQQQTPAENKAESEEMETSQ 553
           E  K +E EE    ++  +E+E++   +E+ H +E     +++    E K   +E +  +
Sbjct: 454 EEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIRE 513

Query: 554 AGSKDKKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKE 613
              K  + ++  + ++ K++     +  + +++ + + +M     E E KM  Q+K+ ++
Sbjct: 514 QEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKM----GEQEEKMQEQEKMRRQ 569

Query: 614 RNDAKNAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVD 673
               +   EE + E ++K+  + EK   +++      K+ + E  + E  E   +Q   +
Sbjct: 570 EEKIREQ-EEKIREQKEKIREQEEKIWEQEE------KIREQEEMMQEQEEKMWEQ--EE 620

Query: 674 KLAELKNLGQPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAA 729
           K+ E +        + QE EE+ +  EE  K  +Q +++    +  ++  +HL+AA
Sbjct: 621 KMCEQEE-------KMQEQEEKMRRQEE--KMWEQEVRLRQQEEKMQEHQEHLEAA 667



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 63/287 (21%), Positives = 130/287 (45%), Gaps = 26/287 (9%)

Query: 502 KSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKKM 561
           K  E E+  E ++  +EEEK++ +QE+   +E +     E   E EE    Q    +KKM
Sbjct: 385 KMHEQEKIREQEEKRQEEEKIR-EQEKRQEQEAKMWRQEEKIREQEEKIREQ----EKKM 439

Query: 562 DQPPQAKKAKVKTSTVDLPIENQLLWQID---REMLNLYIENEGKMIMQDKLEKE----- 613
            +  +    + K    +   E + +W+ +   RE   ++ + E KM  Q+K+ K+     
Sbjct: 440 WRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKE-KMHEQEKIRKQEEKVW 498

Query: 614 -RNDAKNAVEEYVYEMRDKLSGEYEKFVSEDDR-NSFTLKLEDTENWLYEDGEDQPKQVY 671
            + +  +  EE + E  +K+  + EK   ++++      K+ + E  + E  E   +Q  
Sbjct: 499 RQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQ-- 556

Query: 672 VDKLAELKNL-GQPIKIRFQES---EERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLD 727
            +K+ E + +  Q  KIR QE    E++ K+ E+  K  +Q  KI    + +E+     +
Sbjct: 557 EEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKI----REQEEMMQEQE 612

Query: 728 AADMTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKE 774
                + EK   +  +    +  ++ ++    +  V+ ++ E K++E
Sbjct: 613 EKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 659



 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 66/345 (19%), Positives = 142/345 (41%), Gaps = 32/345 (9%)

Query: 504 EENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKKMDQ 563
           E  E+  E ++  +E+E+   +QEE    +++     E K   +E    +   K +++++
Sbjct: 311 EWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEE 370

Query: 564 PPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYI-------ENEGKMIMQDKLEKERND 616
               K+ K++     +  + ++  Q ++      I       E E KM  Q++  +E+ +
Sbjct: 371 MMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEE 430

Query: 617 AKNAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLA 676
                E+ ++   +K+  E EK   E+ R       E  E W  E+   + ++++  K  
Sbjct: 431 KIREQEKKMWRQEEKIH-EQEKIREEEKRQ------EQEEMWRQEEKIREQEEIWRQK-- 481

Query: 677 ELKNLGQPIKIRFQESE---ERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAADMTK 733
             + + +  KIR QE +   +  K+ ++  K  +Q  K+    +   +Q + +      +
Sbjct: 482 --EKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKI-----RE 534

Query: 734 VEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKELTSTCSPIISKPKPKVEPP 793
            E+   E  E M  +     +Q   M    K +  E KI+E        I + K K+   
Sbjct: 535 QEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEK----IREQKEKIR-- 588

Query: 794 KEEQKNAEQNGPVDGQGDNPGPQAAEQGTDTAVPSDSDKKLPEMD 838
           ++E+K  EQ   +  Q +    Q  +         + ++K+ E +
Sbjct: 589 EQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQE 633



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 52/242 (21%), Positives = 102/242 (42%), Gaps = 28/242 (11%)

Query: 499 EVHKSEENEEPMETDQNAKEEEKMQ------VDQEEPHVEEQQQQTPAENK--------- 543
           E  K  E EE  + ++  +E+EK Q        QEE   E++++    E K         
Sbjct: 388 EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIH 447

Query: 544 ------AESEEMETSQAGSKDKKMDQPPQAKKAKVKTSTVD-LPIENQLLWQIDREMLN- 595
                  E +  E  +   +++K+ +  +  + K K    + +  + + +W+ + +M + 
Sbjct: 448 EQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQ 507

Query: 596 --LYIENEGKMIMQDKLEKERNDAKNAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLE 653
                E E KM  Q++  +E+ +     EE + E  + +  + EK   ++++     K+ 
Sbjct: 508 EEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMR 567

Query: 654 DTENWLYEDGEDQPKQVYVDKLAELKNLGQPIKIRFQE---SEERPKLFEELGKQIQQYM 710
             E  + E  E   +Q    +  E K   Q  KIR QE    E+  K++E+  K  +Q  
Sbjct: 568 RQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEE 627

Query: 711 KI 712
           K+
Sbjct: 628 KM 629



 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 65/348 (18%), Positives = 155/348 (44%), Gaps = 35/348 (10%)

Query: 503 SEENEEPM--ETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKK 560
           +++ EE M  + ++  + EEK+Q +QEE   E++++    E K   +E    +   K ++
Sbjct: 295 NQQQEEKMWRQEEKIQEWEEKIQ-EQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRR 353

Query: 561 MDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKL----EKERND 616
            ++    K+ K++          +++W+ + ++  L    E KM  Q+K+    EK + +
Sbjct: 354 QEEMMWEKEEKMRRL-------EEMMWEKEEKIREL----EEKMHEQEKIREQEEKRQEE 402

Query: 617 AKNAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDG-EDQPKQVYVDKL 675
            K   +E   E   K+  + EK   ++++    ++ ++ + W  E+   +Q K    +K 
Sbjct: 403 EKIREQEKRQEQEAKMWRQEEKIREQEEK----IREQEKKMWRQEEKIHEQEKIREEEKR 458

Query: 676 AELKNL-GQPIKIRFQE----SEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAAD 730
            E + +  Q  KIR QE     +E+    E++ KQ ++  +      ++E++    +   
Sbjct: 459 QEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKM 518

Query: 731 MTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKELTSTCSPIISKPKPKV 790
             + EK   +  +    +  ++ ++ +  +   K  E E K++E        + + + K+
Sbjct: 519 WRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEK-----MRRQEEKI 573

Query: 791 EPPKEEQKNAEQNGPVDGQGDNPGPQAAEQGTDTAVPSDSDKKLPEMD 838
              ++E+K  EQ   +  Q +    Q  +      +  + ++K+ E +
Sbjct: 574 R--EQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQE 619


>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
           sapiens]
          Length = 570

 Score = 54.3 bits (129), Expect = 5e-07
 Identities = 42/197 (21%), Positives = 91/197 (46%), Gaps = 6/197 (3%)

Query: 499 EVHKSEENEEPM-ETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSK 557
           E  K +E E  M   ++  +E+E+   +QEE   E++++    E K   +E E  +   K
Sbjct: 374 EQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEK 433

Query: 558 DKKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDA 617
            ++ ++  + ++ K++     +  + +++ + + +M     E EGKM  Q+   +E+ + 
Sbjct: 434 MRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKM----GEQEGKMCEQEAKMQEQEEK 489

Query: 618 KNAVEEYVYEMRDKLSGEYEKFVSEDD-RNSFTLKLEDTENWLYEDGEDQPKQVYVDKLA 676
               EE + E   K+  + EK   +++       K+ + E  + E  E   +Q    +  
Sbjct: 490 MRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQ 549

Query: 677 ELKNLGQPIKIRFQESE 693
           E K   Q +++R QE +
Sbjct: 550 EEKMREQEVRLRQQEEK 566



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 48/276 (17%), Positives = 122/276 (44%), Gaps = 26/276 (9%)

Query: 502 KSEENEEPM-ETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKK 560
           K    EE M E ++  + +E+M  ++EE   E +++    E   E EE    +   ++++
Sbjct: 317 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQE 376

Query: 561 MDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAKNA 620
             Q  +AK                 +W+ + ++     E E K+  Q+++ +E+ +    
Sbjct: 377 KRQEQEAK-----------------MWRQEEKIR----EQEEKIREQEEMMQEQEEKMGE 415

Query: 621 VEEYVYEMRDKLSGEYEKFVSEDDR-NSFTLKLEDTENWLYEDGEDQPKQVYVDKLAELK 679
            EE ++E  +++  + EK   ++++      K+ + E  + E  +++  Q   +K+ E +
Sbjct: 416 QEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIRE--QEEMMQEQEEKMGEQE 473

Query: 680 NLGQPIKIRFQESEERPKLFEE-LGKQIQQYMKIISSFKNKEDQYDHLDAADMTKVEKST 738
                 + + QE EE+ +  EE + +Q ++  +     + +E+     +     + EK  
Sbjct: 474 GKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMC 533

Query: 739 NEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKE 774
            +  +    +  ++ ++    +  V+ ++ E K++E
Sbjct: 534 EQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQE 569



 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 59/274 (21%), Positives = 116/274 (42%), Gaps = 29/274 (10%)

Query: 505 ENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKKMDQP 564
           + E+  E ++  +E+E+   +QEE    +++     E K   +E    +   K +++++ 
Sbjct: 293 QEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEE- 351

Query: 565 PQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAKNAVEEY 624
              ++ K++        E ++  Q  R+      E E KM  Q++  +E+ +     EE 
Sbjct: 352 KMHEQEKIREQEEKRQEEEKIREQEKRQ------EQEAKMWRQEEKIREQEEKIREQEEM 405

Query: 625 VYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKNLGQP 684
           + E  +K+ GE E+            K+ + E  + E  E   +Q    +  E K   Q 
Sbjct: 406 MQEQEEKM-GEQEE------------KMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQE 452

Query: 685 IKIRFQE---SEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAADMTKVEKSTNEA 741
            KIR QE    E+  K+ E+ GK  +Q  K+      ++++        + + EK   E 
Sbjct: 453 EKIREQEEMMQEQEEKMGEQEGKMCEQEAKM-----QEQEEKMRRQEEKIREQEKKIREQ 507

Query: 742 MEWMNNKLNLQNKQSLTM-DPVVKSKEIEAKIKE 774
            E +  +  +  +Q   M +   K  E E K++E
Sbjct: 508 EEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE 541


>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
            [Homo sapiens]
          Length = 2073

 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 92/405 (22%), Positives = 161/405 (39%), Gaps = 60/405 (14%)

Query: 436  RKEPFTLEAYYSSPQDLPYPDPAIAQFSVQKVTPQSDGSSSKVKVKVRVNVHGIFSVSSA 495
            RK  F L  Y  +P + P           QK T +   S S ++++  V   G   +   
Sbjct: 1265 RKTGFKLNLY--TPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLPQ- 1321

Query: 496  SLVEVHKSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAG 555
               E ++ EE   P+  + +  E+ +  + + E   EE++++   E + E EE E    G
Sbjct: 1322 ---EENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEE--GGG 1376

Query: 556  SKDKKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERN 615
            + +K  D     +K + + ST           + D   L+ + E E     ++  E   N
Sbjct: 1377 NVEKDPDGAKSQEKEEPEISTE----------KEDSARLDDHEEEE-----EEDEEPSHN 1421

Query: 616  DAKNAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWL---YEDGEDQPKQVY- 671
            +  +A +E    M    S E EK   E  R SF   LE+ E +L    + G   P+ +  
Sbjct: 1422 EDHDADDEDDSHME---SAEVEK--EELPRESFKEVLENQETFLDLNVQPGHSNPEVLMD 1476

Query: 672  --VDKLA----ELKNL-GQPIKIRFQESEERPKLFEELGKQIQQYMK-IISSFKNKEDQY 723
              VD  A    E K L G P  +   ES+E P   E+  KQ Q+  K + + FK      
Sbjct: 1477 CGVDLTASCNSEPKELAGDPEAV--PESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPAT 1534

Query: 724  DHLDAADMTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKELTSTCSPII 783
              +D+  +  V+  T E+ E           Q  T     +++E    ++  T       
Sbjct: 1535 MEIDSETVQAVQSLTQESSE-----------QDDTFQDCAETQEACRSLQNYTR------ 1577

Query: 784  SKPKPKVEPPKEEQKNAEQNGPVDGQGDNPGPQAAEQGTDTAVPS 828
            +   P++    ++ + ++ + PV     +PG Q+       +VP+
Sbjct: 1578 ADQSPQIATTLDDCQQSDHSSPVSSVHSHPG-QSVRSVNSPSVPA 1621



 Score = 37.7 bits (86), Expect = 0.045
 Identities = 17/60 (28%), Positives = 32/60 (53%)

Query: 505  ENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKKMDQP 564
            E  + +E  + + EEE+ + D+EE   EE++++   E + E EE E     S   ++ +P
Sbjct: 1057 ERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKP 1116



 Score = 36.6 bits (83), Expect = 0.100
 Identities = 21/89 (23%), Positives = 41/89 (46%)

Query: 489  IFSVSSASLVEVHKSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEE 548
            +  +S  S  E  + E+ EE  E ++  ++EE+ + ++EE   E  Q   P   K +S  
Sbjct: 1061 LLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVA 1120

Query: 549  METSQAGSKDKKMDQPPQAKKAKVKTSTV 577
            ++  +     KK  +  +   + V T T+
Sbjct: 1121 IKRKRPFVLKKKRGRKRRRINSSVTTETI 1149



 Score = 32.0 bits (71), Expect = 2.5
 Identities = 70/360 (19%), Positives = 129/360 (35%), Gaps = 70/360 (19%)

Query: 500  VHKSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDK 559
            +H  E      E  Q  +  ++   ++EE   EE++++   E + E EE E  +   ++ 
Sbjct: 1046 LHSPESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEN 1105

Query: 560  KMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAKN 619
                PP+  K +                       ++ I+ +   +++ K  ++R    +
Sbjct: 1106 IQSSPPRLTKPQ-----------------------SVAIKRKRPFVLKKKRGRKRRRINS 1142

Query: 620  AV-EEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLAEL 678
            +V  E + E  + L+   E F + D+           E  + EDG    ++  + K  + 
Sbjct: 1143 SVTTETISETTEVLN---EPFDNSDEERPMPQLEPTCEIEVEEDG----RKPVLRKAFQ- 1194

Query: 679  KNLGQPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAADMTKVE--- 735
                QP K R  E EE        GK    +        N  D   +L        E   
Sbjct: 1195 ---HQPGKKRQTEEEE--------GKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLK 1243

Query: 736  ------KSTNEAM-EWMNN-------KLNLQNKQSLTMDPVVK-SKEIEAKIKELTSTCS 780
                  K T   + +W  N       KLNL       M+P  + + E + +  E  ++ S
Sbjct: 1244 CKQVWPKGTKRGLSKWRQNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPS 1303

Query: 781  PIISKPKPKVEP----PKEEQKNAEQNGPVDGQGDNPGPQAAEQGTDTAVPSDSDKKLPE 836
            PI  + + K       P+EE +  E   PV     +P     E+  D  +  + +++  E
Sbjct: 1304 PIRIEEEVKETGEALLPQEENRREETCAPV-----SPNTSPGEKPEDDLIKPEEEEEEEE 1358


>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 436

 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 55/245 (22%), Positives = 107/245 (43%), Gaps = 22/245 (8%)

Query: 499 EVHKSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKD 558
           ++ K EE     E +Q  K+EE+M   +E+   +E+Q Q   E   + EE    Q   ++
Sbjct: 214 QMQKQEEQMGEQE-EQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQ---EE 269

Query: 559 KKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAK 618
           +  +Q  Q  K K +T   +   E +   +   E +    E E +M  Q++  +E+ +  
Sbjct: 270 QMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMR---EQEEQMREQEEQMREQEEQM 326

Query: 619 NAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLAEL 678
              EE ++E ++++  + E+   ++++             + E  E   KQ    +  E 
Sbjct: 327 GKQEEQMWEQKEQMWEQKEQMWKQEEQ-------------MGEQEEQMQKQEEQVRKQEE 373

Query: 679 KNLGQPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAADMTKVEKST 738
           +   Q  ++R QE + R K  E++G+Q +Q  +     + +E+Q        M K E+  
Sbjct: 374 QMRKQEEQMRKQEEQMR-KQEEQMGEQKEQMGEQKEQMREQEEQMGE-QKEQMRKQEEHM 431

Query: 739 NEAME 743
            E  E
Sbjct: 432 GEQKE 436



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 41/258 (15%), Positives = 112/258 (43%), Gaps = 11/258 (4%)

Query: 504 EENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKKMDQ 563
           E+  +  E +   +E+E    +QE    E+++Q    E + + +E +  +   + +K ++
Sbjct: 175 EQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEE 234

Query: 564 PPQAKKAKVKTSTVDLPIENQLLWQIDREMLNL--YIENEGKMIMQDKLEKERNDAKNAV 621
               ++ +V+     +  + + + + + +M      +  + + +++ K + E+ +     
Sbjct: 235 QMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQ 294

Query: 622 EEYVYEMRDKLSGEYEKF-VSEDDRNSFTLKLEDTENWLYEDGE---DQPKQVYVDKLAE 677
           EE + E  +++  + E+    E+       ++   E  ++E  E   +Q +Q++  +   
Sbjct: 295 EEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQE--- 351

Query: 678 LKNLGQPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAADMTKVEKS 737
            + +G+  +   ++ E+  K  E++ KQ +Q  K     + +E+Q        M + ++ 
Sbjct: 352 -EQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGE-QKEQMGEQKEQ 409

Query: 738 TNEAMEWMNNKLNLQNKQ 755
             E  E M  +     KQ
Sbjct: 410 MREQEEQMGEQKEQMRKQ 427



 Score = 39.3 bits (90), Expect = 0.015
 Identities = 70/325 (21%), Positives = 132/325 (40%), Gaps = 26/325 (8%)

Query: 497 LVEVHKSE------ENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEME 550
           LVE  KSE      E +  +ETD+    +E  QV ++E  V EQ+ Q   E + +  E E
Sbjct: 22  LVETEKSEIQLHIKELKRKLETDKIPLPQEG-QVREQEGQVREQEGQV-REQEGQVREQE 79

Query: 551 TSQAGSKDKKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKL 610
                 + +  +Q  Q ++ + +    +  +  Q   Q+ RE      E EG++  Q+  
Sbjct: 80  GQVREQEGQVREQEGQVREQEGQVREQEGQVREQ-EGQV-REQEGQVREQEGQVREQEGQ 137

Query: 611 EKERNDAKNAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQV 670
            +E+       E  V E   ++  E E  V E +      ++ + E  + E  E Q ++ 
Sbjct: 138 VREQEGQVREQEGQVREQEGQVR-EQEGQVREQEG-----QVREQEGQVREQ-EGQVREQ 190

Query: 671 YVDKLAELKNLGQPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLD--- 727
                 +   +G+  +   ++ E+  K  E++G+Q +Q  K       +E+Q    +   
Sbjct: 191 EGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQV 250

Query: 728 ---AADMTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKELTSTCSPIIS 784
                 M K E+   E  E M  +     KQ    +   ++ E E +++E          
Sbjct: 251 QKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEE 310

Query: 785 KPKPKVEPPKEEQKNAEQNGPVDGQ 809
           + + + E  +E++   EQ G  + Q
Sbjct: 311 QMREQEEQMREQE---EQMGKQEEQ 332



 Score = 36.6 bits (83), Expect = 0.100
 Identities = 27/149 (18%), Positives = 71/149 (47%), Gaps = 11/149 (7%)

Query: 497 LVEVHKSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGS 556
           L +  ++E+ E+  E ++  +E+E+   +QEE   E+++Q    E +   +E +  +   
Sbjct: 279 LKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWE--Q 336

Query: 557 KDKKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERND 616
           K++  +Q  Q  K + +        E +   Q   E +    + E +M  Q++  +++ +
Sbjct: 337 KEQMWEQKEQMWKQEEQMG------EQEEQMQKQEEQVR---KQEEQMRKQEEQMRKQEE 387

Query: 617 AKNAVEEYVYEMRDKLSGEYEKFVSEDDR 645
                EE + E ++++  + E+   ++++
Sbjct: 388 QMRKQEEQMGEQKEQMGEQKEQMREQEEQ 416


>gi|239752551 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 238

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 50/218 (22%), Positives = 97/218 (44%), Gaps = 11/218 (5%)

Query: 505 ENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKKMDQP 564
           E E   E ++  +EEE+M  +QEE   E++++    E K   +E +  +   K  + ++ 
Sbjct: 3   EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 62

Query: 565 PQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAKNAVEEY 624
              ++ K+      LP + + +W+ D E L    E   +  M  ++EK R + K   EE 
Sbjct: 63  MWEQEEKM-WEQQRLPEQKEKMWEQD-ERLREKEERMREQKMWQQVEKMR-EKKKTQEEK 119

Query: 625 VYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKNLGQP 684
           + E  +K+  + E    +++      K+++ E  ++E  E   +Q    +  E K  GQ 
Sbjct: 120 MQEQEEKMQEQEEMMWEQEE------KMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQE 173

Query: 685 IKIRFQE--SEERPKLFEELGKQIQQYMKIISSFKNKE 720
            K+R  E    E  +   +     Q+ M++    KN +
Sbjct: 174 EKMRDVEPAGGEAGEGSPQDNPTAQEIMQLFCGMKNAQ 211



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 45/184 (24%), Positives = 78/184 (42%), Gaps = 14/184 (7%)

Query: 499 EVHKSEENEEPMETDQNAK---EEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAG 555
           E  K    EE M  +Q  K   +EEKM+  +E+   +E++ Q   E   E EE    Q  
Sbjct: 9   EREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEE 68

Query: 556 SKDKKMDQPPQAKKAKVKTSTV---DLPIENQLLWQIDREML-------NLYIENEGKMI 605
              ++   P Q +K   +   +   +  +  Q +WQ   +M            E E KM 
Sbjct: 69  KMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEKMQ 128

Query: 606 MQDKLEKERNDAKNAVEEYVYEMRDKLSGEYEKFVSEDDR-NSFTLKLEDTENWLYEDGE 664
            Q+++  E+ +     EE ++E  +K+  + EK   ++++      K+ D E    E GE
Sbjct: 129 EQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVEPAGGEAGE 188

Query: 665 DQPK 668
             P+
Sbjct: 189 GSPQ 192



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 41/193 (21%), Positives = 93/193 (48%), Gaps = 16/193 (8%)

Query: 517 KEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKKMDQPPQAKKAKVKTST 576
           +EEE+M+ ++E+   EE++     E K + +E +  +   K  + ++  Q ++ K+    
Sbjct: 2   REEERMR-EREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 60

Query: 577 VDLPIENQLLWQIDREMLNLYIENEGKMIMQDK--LEKERNDAKNAVEEYVYEMRDKLSG 634
             +  + + +W+  R       E + KM  QD+   EKE    +  + + V +MR+K   
Sbjct: 61  EKMWEQEEKMWEQQR-----LPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKT 115

Query: 635 EYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKNLGQPIKIRFQESEE 694
           + EK   +++      K+++ E  ++E  E   +Q   +K+ E +   +  + + +E EE
Sbjct: 116 QEEKMQEQEE------KMQEQEEMMWEQEEKMQEQ--EEKMWEQEEKMREQEEKMREQEE 167

Query: 695 RPKLFEELGKQIQ 707
           + +  EE  + ++
Sbjct: 168 KMQGQEEKMRDVE 180


>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
           protein 6 [Homo sapiens]
          Length = 724

 Score = 50.8 bits (120), Expect = 5e-06
 Identities = 49/247 (19%), Positives = 111/247 (44%), Gaps = 27/247 (10%)

Query: 505 ENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEM--------------- 549
           + E+  E ++  +E+E+    QEE  + EQ++    E + E EEM               
Sbjct: 482 QEEKIREQEEKIREQEEKMWRQEEK-IHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWR 540

Query: 550 ---ETSQAGSKDKKMDQPPQAKKAKVKTSTVDLPIENQLLWQID---REMLNLYIENEGK 603
              +  +   K +K ++    ++ K+      +  + + +W+ +   RE      E E K
Sbjct: 541 QKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEK 600

Query: 604 MIMQDKLEKERNDAKNAVEEYVYEMRDKLSGEYEKFVSEDDR-NSFTLKLEDTENWLYED 662
           +  Q+++ +E+ +     EE + E  +K+  + EK   ++++      K+ + E  + E 
Sbjct: 601 IREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIRE- 659

Query: 663 GEDQPKQVYVDKLAELKNLGQPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQ 722
            +++  Q   +K+ E +      + + QE EE+ +  EE  K  +Q +++    +  ++ 
Sbjct: 660 -QEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEE--KMWEQEVRLRQQEEKMQEH 716

Query: 723 YDHLDAA 729
            +HL+AA
Sbjct: 717 QEHLEAA 723



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 67/350 (19%), Positives = 155/350 (44%), Gaps = 30/350 (8%)

Query: 503 SEENEEPM--ETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKK 560
           +++ EE M  + ++  + EEK+Q +QEE   E++++    E K   +E    +   K ++
Sbjct: 356 NQQQEEKMWRQEEKIQEWEEKIQ-EQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRR 414

Query: 561 MDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKL----EKERND 616
            ++    K+ K++        + +++W+ + ++  L    E KM  Q+K+    EK + +
Sbjct: 415 QEEMMWEKEEKMRR-------QEEMMWEKEEKIREL----EEKMHEQEKIREQEEKRQEE 463

Query: 617 AKNAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDG-EDQPKQVYVDKL 675
            K   +E   E   K+  + EK   ++++    ++ ++ + W  E+   +Q K    +K 
Sbjct: 464 EKIREQEKRQEQEAKMWRQEEKIREQEEK----IREQEEKMWRQEEKIHEQEKIREEEKR 519

Query: 676 AELKNL-GQPIKIRFQES--EERPKLFEE---LGKQIQQYMKIISSFKNKEDQYDHLDAA 729
            E + +  Q  KIR QE    ++ K+ E+   + KQ ++  +      ++E++    +  
Sbjct: 520 QEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEK 579

Query: 730 DMTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKELTSTCSPIISKPKPK 789
              + EK   +  +    +  ++ ++ +T +   K  E E K+ E          K + +
Sbjct: 580 VWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQ 639

Query: 790 VEPPKEEQKN-AEQNGPVDGQGDNPGPQAAEQGTDTAVPSDSDKKLPEMD 838
            E  +E++K   EQ   +  Q +    Q  +         + ++K+ E +
Sbjct: 640 EEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQE 689



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 28/135 (20%), Positives = 66/135 (48%), Gaps = 11/135 (8%)

Query: 504 EENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKKMDQ 563
           E+ E+  E ++  +E+E+M  +QEE   E++++    E K + +E +  +   K ++ ++
Sbjct: 589 EQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEK 648

Query: 564 PPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAKNAVEE 623
             + ++ K++     +  + + +W           E E KM  Q++  +E+ +     EE
Sbjct: 649 KIREQEEKIREQEEMMQEQEEKMW-----------EQEEKMCEQEEKMQEQEEKMRRQEE 697

Query: 624 YVYEMRDKLSGEYEK 638
            ++E   +L  + EK
Sbjct: 698 KMWEQEVRLRQQEEK 712



 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 59/284 (20%), Positives = 125/284 (44%), Gaps = 18/284 (6%)

Query: 502 KSEENEEPM-ETDQNAKEEEKMQVDQEEP--HVEEQQQQTPAENKAESEEMETSQAGSKD 558
           K    EE M E ++  + +E+M  ++EE    +EE+  +     + E +  E  +   ++
Sbjct: 411 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQE 470

Query: 559 KKMDQPPQ--AKKAKVKTSTVDLPIENQLLWQIDREMLNL-YIENEGKMIMQDKLEKERN 615
           K+ +Q  +   ++ K++     +  + + +W+ + ++     I  E K   Q++ E  R 
Sbjct: 471 KRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEK--RQEQEEMWRQ 528

Query: 616 DAKNAVEEYVYEMRDKLSGEYEKFVSEDDRN-SFTLKLEDTENWLYEDGEDQPKQVYVDK 674
           + K   +E ++  ++K+  + EK   ++++      K+ D E  + E  E   +Q    +
Sbjct: 529 EEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIR 588

Query: 675 LAELKNLGQPIKIRFQE---SEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAADM 731
             E K   Q  KIR QE    E+  K+ E+  K  +Q  K+      ++++        +
Sbjct: 589 EQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKM-----QEQEEKMRRQEEKI 643

Query: 732 TKVEKSTNEAMEWMNNKLNLQNKQSLTM-DPVVKSKEIEAKIKE 774
            + EK   E  E +  +  +  +Q   M +   K  E E K++E
Sbjct: 644 REQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE 687



 Score = 30.4 bits (67), Expect = 7.1
 Identities = 19/79 (24%), Positives = 39/79 (49%), Gaps = 1/79 (1%)

Query: 502 KSEENEEPMET-DQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKK 560
           K +E EE M   ++  +E+EK   +QEE   E+++     E K   +E +  +   K ++
Sbjct: 628 KMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE 687

Query: 561 MDQPPQAKKAKVKTSTVDL 579
            ++  + ++ K+    V L
Sbjct: 688 QEEKMRRQEEKMWEQEVRL 706


>gi|8922950 meiosis-specific nuclear structural 1 [Homo sapiens]
          Length = 495

 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 70/322 (21%), Positives = 142/322 (44%), Gaps = 49/322 (15%)

Query: 500 VHKSEENEEPMETDQNAKEEEKMQVD----QEEPHVEEQQQQTPAENKAESEEMETSQAG 555
           + K+EEN+   E     K+EEK+ ++    + E   +E+ +Q   EN  E  E+E     
Sbjct: 73  IQKAEENKRLKELQ--LKQEEKLAMELAKLKHESLKDEKMRQQVRENSIELRELEKKLKA 130

Query: 556 SKDKKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDK-LEKER 614
           +   K      A+K  +K   +          + D E+    +E   ++I ++   E +R
Sbjct: 131 AYMNKERAAQIAEKDAIKYEQM----------KRDAEIAKTMMEEHKRIIKEENAAEDKR 180

Query: 615 NDAKNA----VEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQV 670
           N AK      +E+ + E   K    YE+ + E       L +++    +YE+ + + +Q 
Sbjct: 181 NKAKAQYYLDLEKQLEEQEKKKQEAYEQLLKE------KLMIDEIVRKIYEEDQLEKQQ- 233

Query: 671 YVDKLAELKNLGQPIKIRFQESEE--RPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDA 728
              KL ++  + + I+  FQ+ +   R K  EE+ ++ ++ ++  +  + +E+       
Sbjct: 234 ---KLEKMNAMRRYIE-EFQKEQALWRKKKREEMEEENRKIIEFANMQQQREED------ 283

Query: 729 ADMTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKE-IEAKIKELTSTCSPIISKPK 787
             M KV+++  +       +L LQN  +  ++ +++ +E +E   +EL       I K K
Sbjct: 284 -RMAKVQENEEK-------RLQLQNALTQKLEEMLRQREDLEQVRQELYQEEQAEIYKSK 335

Query: 788 PKVEPPKEEQKNAEQNGPVDGQ 809
            K E  K+ +K  E     + Q
Sbjct: 336 LKEEAEKKLRKQKEMKQDFEEQ 357



 Score = 37.7 bits (86), Expect = 0.045
 Identities = 53/242 (21%), Positives = 101/242 (41%), Gaps = 35/242 (14%)

Query: 502 KSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKKM 561
           K +ENEE     QNA  ++  ++ ++   +E+ +Q+   E +AE  +       SK K+ 
Sbjct: 287 KVQENEEKRLQLQNALTQKLEEMLRQREDLEQVRQELYQEEQAEIYK-------SKLKEE 339

Query: 562 DQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAKNAV 621
            +    K+ ++K    +     +L+ Q  +E      EN  K ++    E +R +  NA 
Sbjct: 340 AEKKLRKQKEMKQDFEEQMALKELVLQAAKE----EEENFRKTMLAKFAEDDRIELMNAQ 395

Query: 622 EEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKNL 681
           ++ + ++  + +   EK + E  +     K  + E W  +    Q +Q +++ + E    
Sbjct: 396 KQRMKQLEHRRA--VEKLIEERRQQFLADKQRELEEWQLQ----QRRQGFINAIIE---- 445

Query: 682 GQPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAADMTKVEKSTNEA 741
                      EER KL +E    +  Y+        KED  D L   +  KV +  +E 
Sbjct: 446 -----------EERLKLLKEHATNLLGYLP--KGVFKKEDDIDLL-GEEFRKVYQQRSEI 491

Query: 742 ME 743
            E
Sbjct: 492 CE 493


>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 750

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 66/353 (18%), Positives = 141/353 (39%), Gaps = 28/353 (7%)

Query: 504 EENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKKMDQ 563
           E+ E+  E ++  + +E+M  ++EE    +++     E K   +E    +   K ++ ++
Sbjct: 325 EQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEE 384

Query: 564 PPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYI-------ENEGKMIMQDKLEKERND 616
               K+ K++     +  + ++  Q ++      I       E E KM  Q++  +E+ +
Sbjct: 385 MMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEE 444

Query: 617 AKNAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLA 676
                E+ ++   +K+  E EK   E+ R       E  E W  E+   + ++++  K  
Sbjct: 445 KIREQEKKMWRQEEKIH-EQEKIREEEKRQ------EQEEMWRQEEKIHEQEEIWRQK-- 495

Query: 677 ELKNLGQPIKIRFQES----------EERPKLFEELGKQIQQYMKIISSFKNKEDQYDHL 726
             K   Q  KIR QE           E+  K+ E+  K  +Q  KI    +   ++    
Sbjct: 496 -EKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMH 554

Query: 727 DAADMTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKELTSTCSPIISKP 786
           +   + + EK   +  +    +  ++ ++        K +E E K +E          K 
Sbjct: 555 EQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKI 614

Query: 787 KPKVEPPKE-EQKNAEQNGPVDGQGDNPGPQAAEQGTDTAVPSDSDKKLPEMD 838
           + + E  +E E+K  EQ   +  Q +    Q  + G       + ++K+ E +
Sbjct: 615 REQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQE 667



 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 28/135 (20%), Positives = 65/135 (48%), Gaps = 11/135 (8%)

Query: 504 EENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKKMDQ 563
           E+ E+  E ++  +E+E+M  +QEE   E++++    E K + +E    +   K ++ ++
Sbjct: 623 EQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEK 682

Query: 564 PPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAKNAVEE 623
             + ++ K++     +  + + +W           E E KM  Q++  +E+ +     EE
Sbjct: 683 KIREQEEKIREQEEMMQEQEEKMW-----------EQEEKMCEQEEKMQEQEEKMRRQEE 731

Query: 624 YVYEMRDKLSGEYEK 638
            ++E   +L  + EK
Sbjct: 732 KMWEQEVRLRQQEEK 746



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 65/277 (23%), Positives = 117/277 (42%), Gaps = 25/277 (9%)

Query: 505 ENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKKMDQP 564
           + E+  E ++  +E+EK    QEE  + EQ++    E + E EEM       +++K+ + 
Sbjct: 435 QEEKIREQEEKIREQEKKMWRQEEK-IHEQEKIREEEKRQEQEEM-----WRQEEKIHEQ 488

Query: 565 PQAKKAKVKTSTVDLPIENQ--LLWQID---REMLNLYIENEGKMIMQDKLEKERNDAKN 619
            +  + K K    +  I  Q   +W+ +   RE      E E KM  Q+  EK R   + 
Sbjct: 489 EEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQE--EKIREQEEM 546

Query: 620 AVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLAELK 679
             EE     ++K+  E ++   ED       K+ + E  ++   E   +Q    +  E K
Sbjct: 547 WREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEK 606

Query: 680 NLGQPIKIRFQES--EERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAADMTKVEKS 737
              Q  KIR QE   +E+ +   E  ++I++  ++    + K  + +        K+++ 
Sbjct: 607 MWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQ 666

Query: 738 TNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKE 774
             E M     K+  Q K         K +E E KI+E
Sbjct: 667 -EETMWRQEEKIREQEK---------KIREQEEKIRE 693



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 42/197 (21%), Positives = 89/197 (45%), Gaps = 13/197 (6%)

Query: 499 EVHKSEENEEPM-ETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSK 557
           E  K +E E+ M   ++  +E+E+    QEE   E+++++   E K   +E +  +   K
Sbjct: 561 EEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEK 620

Query: 558 DKKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDA 617
            ++ ++  + ++ K++        E + + Q   E +    E E KM  Q++  +E+ + 
Sbjct: 621 IQEQEEKIREQEEKIR--------EQEEMTQEQEEKMG---EQEEKMCEQEEKMQEQEET 669

Query: 618 KNAVEEYVYEMRDKLSGEYEKFVSEDD-RNSFTLKLEDTENWLYEDGEDQPKQVYVDKLA 676
               EE + E   K+  + EK   +++       K+ + E  + E  E   +Q    +  
Sbjct: 670 MWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQ 729

Query: 677 ELKNLGQPIKIRFQESE 693
           E K   Q +++R QE +
Sbjct: 730 EEKMWEQEVRLRQQEEK 746



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 60/294 (20%), Positives = 123/294 (41%), Gaps = 27/294 (9%)

Query: 502 KSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKKM 561
           K  E E+  E ++  +EEEK   +QE+   +E +     E   E EE    Q    +KKM
Sbjct: 399 KMHEQEKIREQEEKRQEEEK-IREQEKRQEQEAKMWRQEEKIREQEEKIREQ----EKKM 453

Query: 562 DQPPQAKKAKVKTSTVDLPIENQLLWQID---REMLNLYIENEGKMIMQDKLEKERNDAK 618
            +  +    + K    +   E + +W+ +    E   ++ + E     ++K+ K+     
Sbjct: 454 WRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVW 513

Query: 619 NAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYED---GEDQPKQVYVDKL 675
              EE + E  +K+  + EK   ++++     ++   E  ++E     E++ +Q   DK+
Sbjct: 514 RQ-EEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKM 572

Query: 676 ---------AELKNLGQPIKIRFQE---SEERPKLF---EELGKQIQQYMKIISSFKNKE 720
                     E K   Q  KIR QE    E+  K++   E++ +Q ++  +     + +E
Sbjct: 573 WRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQE 632

Query: 721 DQYDHLDAADMTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKE 774
           ++    +     + EK   +  +    +  +Q ++        K +E E KI+E
Sbjct: 633 EKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIRE 686



 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 70/309 (22%), Positives = 131/309 (42%), Gaps = 56/309 (18%)

Query: 503 SEENEEPM--ETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKK 560
           +++ EE M  + ++  + EEK+Q  +E+   +E++ +   E     EEM       K++K
Sbjct: 295 NQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEM----MWEKEEK 350

Query: 561 MDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAKNA 620
           M +                  + +++W           E E KM  Q+++  E+ +    
Sbjct: 351 MRR------------------QEEMMW-----------EKEEKMRRQEEMMWEKEEKMRR 381

Query: 621 VEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKN 680
            EE ++E  +K+    EK   ++       K+ + E    E  E++ ++    +  E K 
Sbjct: 382 QEEMMWEKEEKIRELEEKMHEQE-------KIREQEEKRQE--EEKIREQEKRQEQEAKM 432

Query: 681 LGQPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAADMTKVEKSTNE 740
             Q  KIR QE     K+ E+  K  +Q  KI    K +E++    +  +M + E+  +E
Sbjct: 433 WRQEEKIREQEE----KIREQEKKMWRQEEKIHEQEKIREEE-KRQEQEEMWRQEEKIHE 487

Query: 741 AME-W-MNNKLNLQNKQSLTMDPVV-----KSKEIEAKIKELTSTCSPIISKPKPKVEPP 793
             E W    K++ Q ++    +  V     K +E E KI+E          K + + E  
Sbjct: 488 QEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMW 547

Query: 794 KEEQKNAEQ 802
           +EE+K  EQ
Sbjct: 548 REEEKMHEQ 556



 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 57/290 (19%), Positives = 117/290 (40%), Gaps = 33/290 (11%)

Query: 502 KSEENEEPM-ETDQNAKEEEKMQVDQEEP--HVEEQQQQTPAENKAESEEMETSQAGSKD 558
           K    EE M E ++  + +E+M  ++EE    +EE+  +     + E +  E  +   ++
Sbjct: 364 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQE 423

Query: 559 KKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQD----KLEKER 614
           K+ +Q  +  + + K                 RE      E E KM  Q+    + EK R
Sbjct: 424 KRQEQEAKMWRQEEKI----------------REQEEKIREQEKKMWRQEEKIHEQEKIR 467

Query: 615 NDAKNAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVDK 674
            + K   +E ++   +K+  + E +  ++  +    K+   E  ++   E   +Q    +
Sbjct: 468 EEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIR 527

Query: 675 LAELKNLGQPIKIRFQES--------EERPKLFEELGKQIQQ--YMKIISSFKNKEDQYD 724
             E K   Q  KIR QE          E+ K++EE  +Q Q+    +     + +E++  
Sbjct: 528 EQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVW 587

Query: 725 HLDAADMTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKE 774
             +     + EK   +  +    +  ++ ++    +   K +E E KI+E
Sbjct: 588 RQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIRE 637


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.129    0.360 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,315,269
Number of Sequences: 37866
Number of extensions: 1474647
Number of successful extensions: 12633
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 201
Number of HSP's successfully gapped in prelim test: 540
Number of HSP's that attempted gapping in prelim test: 7884
Number of HSP's gapped (non-prelim): 3227
length of query: 840
length of database: 18,247,518
effective HSP length: 111
effective length of query: 729
effective length of database: 14,044,392
effective search space: 10238361768
effective search space used: 10238361768
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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