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Search of human proteins with 38327039
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|38327039 heat shock 70kDa protein 4 [Homo sapiens]
(840 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|38327039 heat shock 70kDa protein 4 [Homo sapiens] 1665 0.0
gi|31541941 heat shock 70kDa protein 4-like [Homo sapiens] 1088 0.0
gi|42544159 heat shock 105kD [Homo sapiens] 1082 0.0
gi|195976805 hypoxia up-regulated 1 precursor [Homo sapiens] 314 2e-85
gi|5453832 hypoxia up-regulated 1 precursor [Homo sapiens] 314 2e-85
gi|34419635 heat shock 70kDa protein 6 (HSP70B') [Homo sapiens] 301 2e-81
gi|167466173 heat shock 70kDa protein 1B [Homo sapiens] 294 3e-79
gi|194248072 heat shock 70kDa protein 1A [Homo sapiens] 294 3e-79
gi|124256496 heat shock 70kDa protein 1-like [Homo sapiens] 293 6e-79
gi|5729877 heat shock 70kDa protein 8 isoform 1 [Homo sapiens] 288 1e-77
gi|16507237 heat shock 70kDa protein 5 [Homo sapiens] 284 2e-76
gi|13676857 heat shock 70kDa protein 2 [Homo sapiens] 271 2e-72
gi|24234686 heat shock 70kDa protein 8 isoform 2 [Homo sapiens] 270 5e-72
gi|24234688 heat shock 70kDa protein 9 precursor [Homo sapiens] 219 8e-57
gi|82880658 heat shock 70kDa protein 14 isoform 1 [Homo sapiens] 191 2e-48
gi|48928056 heat shock protein 70kDa family member 13 precursor ... 163 7e-40
gi|221219020 NYD-SP11 protein [Homo sapiens] 60 1e-08
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 60 1e-08
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 60 1e-08
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 59 1e-08
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 58 3e-08
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 55 2e-07
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 55 3e-07
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 54 5e-07
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 53 1e-06
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 52 2e-06
gi|239752551 PREDICTED: hypothetical protein [Homo sapiens] 52 2e-06
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 51 5e-06
gi|8922950 meiosis-specific nuclear structural 1 [Homo sapiens] 50 1e-05
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 49 2e-05
>gi|38327039 heat shock 70kDa protein 4 [Homo sapiens]
Length = 840
Score = 1665 bits (4312), Expect = 0.0
Identities = 840/840 (100%), Positives = 840/840 (100%)
Query: 1 MSVVGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISNA 60
MSVVGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISNA
Sbjct: 1 MSVVGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISNA 60
Query: 61 KNTVQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTAM 120
KNTVQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTAM
Sbjct: 61 KNTVQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTAM 120
Query: 121 LLSKLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVALA 180
LLSKLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVALA
Sbjct: 121 LLSKLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVALA 180
Query: 181 YGIYKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVL 240
YGIYKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVL
Sbjct: 181 YGIYKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVL 240
Query: 241 VNHFCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMNDVDVSGT 300
VNHFCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMNDVDVSGT
Sbjct: 241 VNHFCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMNDVDVSGT 300
Query: 301 MNRGKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEKISKFFGK 360
MNRGKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEKISKFFGK
Sbjct: 301 MNRGKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEKISKFFGK 360
Query: 361 ELSTTLNADEAVTRGCALQCAILSPAFKVREFSITDVVPYPISLRWNSPAEEGSSDCEVF 420
ELSTTLNADEAVTRGCALQCAILSPAFKVREFSITDVVPYPISLRWNSPAEEGSSDCEVF
Sbjct: 361 ELSTTLNADEAVTRGCALQCAILSPAFKVREFSITDVVPYPISLRWNSPAEEGSSDCEVF 420
Query: 421 SKNHAAPFSKVLTFYRKEPFTLEAYYSSPQDLPYPDPAIAQFSVQKVTPQSDGSSSKVKV 480
SKNHAAPFSKVLTFYRKEPFTLEAYYSSPQDLPYPDPAIAQFSVQKVTPQSDGSSSKVKV
Sbjct: 421 SKNHAAPFSKVLTFYRKEPFTLEAYYSSPQDLPYPDPAIAQFSVQKVTPQSDGSSSKVKV 480
Query: 481 KVRVNVHGIFSVSSASLVEVHKSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPA 540
KVRVNVHGIFSVSSASLVEVHKSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPA
Sbjct: 481 KVRVNVHGIFSVSSASLVEVHKSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPA 540
Query: 541 ENKAESEEMETSQAGSKDKKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIEN 600
ENKAESEEMETSQAGSKDKKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIEN
Sbjct: 541 ENKAESEEMETSQAGSKDKKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIEN 600
Query: 601 EGKMIMQDKLEKERNDAKNAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLY 660
EGKMIMQDKLEKERNDAKNAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLY
Sbjct: 601 EGKMIMQDKLEKERNDAKNAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLY 660
Query: 661 EDGEDQPKQVYVDKLAELKNLGQPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKE 720
EDGEDQPKQVYVDKLAELKNLGQPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKE
Sbjct: 661 EDGEDQPKQVYVDKLAELKNLGQPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKE 720
Query: 721 DQYDHLDAADMTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKELTSTCS 780
DQYDHLDAADMTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKELTSTCS
Sbjct: 721 DQYDHLDAADMTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKELTSTCS 780
Query: 781 PIISKPKPKVEPPKEEQKNAEQNGPVDGQGDNPGPQAAEQGTDTAVPSDSDKKLPEMDID 840
PIISKPKPKVEPPKEEQKNAEQNGPVDGQGDNPGPQAAEQGTDTAVPSDSDKKLPEMDID
Sbjct: 781 PIISKPKPKVEPPKEEQKNAEQNGPVDGQGDNPGPQAAEQGTDTAVPSDSDKKLPEMDID 840
>gi|31541941 heat shock 70kDa protein 4-like [Homo sapiens]
Length = 839
Score = 1088 bits (2813), Expect = 0.0
Identities = 541/853 (63%), Positives = 669/853 (78%), Gaps = 27/853 (3%)
Query: 1 MSVVGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISNA 60
MSVVGIDLGF +CY+AVAR+GGIETIANEYSDRCTPACIS G + R+IG AAKSQ+++N
Sbjct: 1 MSVVGIDLGFLNCYIAVARSGGIETIANEYSDRCTPACISLGSRTRAIGNAAKSQIVTNV 60
Query: 61 KNTVQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTAM 120
+NT+ GFK+ HGR+F DP V+ E+ L Y++ ++P G G+KV Y+EEER F EQVT M
Sbjct: 61 RNTIHGFKKLHGRSFDDPIVQTERIRLPYELQKMPNGSAGVKVRYLEEERPFAIEQVTGM 120
Query: 121 LLSKLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVALA 180
LL+KLKET+E+ LKKPV DCV+S+P F+TDAERRSVM A Q+AGLNCLRLMNETTAVALA
Sbjct: 121 LLAKLKETSENALKKPVADCVISIPSFFTDAERRSVMAAAQVAGLNCLRLMNETTAVALA 180
Query: 181 YGIYKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVL 240
YGIYKQDLP L+EKPRNVVF+DMGHSAYQV VCAFN+GKLKVLAT FD LGGR FDE L
Sbjct: 181 YGIYKQDLPPLDEKPRNVVFIDMGHSAYQVLVCAFNKGKLKVLATTFDPYLGGRNFDEAL 240
Query: 241 VNHFCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMNDVDVSGT 300
V++FC+EF KYK+++K RALLRL QECEKLKKLMSANASDLPL+IECFMND+DVS
Sbjct: 241 VDYFCDEFKTKYKINVKENSRALLRLYQECEKLKKLMSANASDLPLNIECFMNDLDVSSK 300
Query: 301 MNRGKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEKISKFFGK 360
MNR +F ++C LLARVEPPL++V+EQ L++EDI ++EIVGGATRIPAVKE+I+KFF K
Sbjct: 301 MNRAQFEQLCASLLARVEPPLKAVMEQANLQREDISSIEIVGGATRIPAVKEQITKFFLK 360
Query: 361 ELSTTLNADEAVTRGCALQCAILSPAFKVREFSITDVVPYPISLRWNSPAEEGSSDCEVF 420
++STTLNADEAV RGCALQCAILSPAFKVREFSITD+VPY I+LRW + E+GS +CEVF
Sbjct: 361 DISTTLNADEAVARGCALQCAILSPAFKVREFSITDLVPYSITLRWKTSFEDGSGECEVF 420
Query: 421 SKNHAAPFSKVLTFYRKEPFTLEAYYSSPQDLPYPDPAIAQFSVQKVTPQSDGSSSKVKV 480
KNH APFSKV+TF++KEPF LEA+Y++ ++PYPD I F++Q V PQSDG SSKVKV
Sbjct: 421 CKNHPAPFSKVITFHKKEPFELEAFYTNLHEVPYPDARIGSFTIQNVFPQSDGDSSKVKV 480
Query: 481 KVRVNVHGIFSVSSASLVEVH--KSEENEEPMETDQNAKEE-----EKMQVDQEEPHVEE 533
KVRVN+HGIFSV+SAS++E + + ++ PMET+ + K E +KMQVDQEE H +
Sbjct: 481 KVRVNIHGIFSVASASVIEKQNLEGDHSDAPMETETSFKNENKDNMDKMQVDQEEGHQKC 540
Query: 534 QQQQTPAENKAESEEMETSQAGSKDKKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREM 593
+ TP E + S K +++Q KK KVK ++DLPI++ L Q+ +++
Sbjct: 541 HAEHTPEEEIDHTGAKTKSAVSDKQDRLNQ--TLKKGKVK--SIDLPIQSSLCRQLGQDL 596
Query: 594 LNLYIENEGKMIMQDKLEKERNDAKNAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLE 653
LN YIENEGKMIMQDKLEKERNDAKNAVEEYVY+ RD+L YEKF++ +D + + LE
Sbjct: 597 LNSYIENEGKMIMQDKLEKERNDAKNAVEEYVYDFRDRLGTVYEKFITPEDLSKLSAVLE 656
Query: 654 DTENWLYEDGEDQPKQVYVDKLAELKNLGQPIKIRFQESEERPKLFEELGKQIQQYMKII 713
DTENWLYEDGEDQPKQVYVDKL ELK GQPI++++ E EERPK +LGK+IQ MK+I
Sbjct: 657 DTENWLYEDGEDQPKQVYVDKLQELKKYGQPIQMKYMEHEERPKALNDLGKKIQLVMKVI 716
Query: 714 SSFKNKEDQYDHLDAADMTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIK 773
+++NK+++YDHLD +M KVEK ++AM W+N+K+N QNK SLT DPVVK EI AK K
Sbjct: 717 EAYRNKDERYDHLDPTEMEKVEKCISDAMSWLNSKMNAQNKLSLTQDPVVKVSEIVAKSK 776
Query: 774 ELTSTCSPIISKPKPKVEPPKEEQK-NAEQNGPVDGQGDNPGPQAAEQGTDTAVPSDSD- 831
EL + C+PII KPKPK E P+++ K N+E NGP+DGQ GT+T S D
Sbjct: 777 ELDNFCNPIIYKPKPKAEVPEDKPKANSEHNGPMDGQ----------SGTETKSDSTKDS 826
Query: 832 ----KKLPEMDID 840
K EM++D
Sbjct: 827 SQHTKSSGEMEVD 839
>gi|42544159 heat shock 105kD [Homo sapiens]
Length = 858
Score = 1082 bits (2798), Expect = 0.0
Identities = 539/822 (65%), Positives = 652/822 (79%), Gaps = 20/822 (2%)
Query: 1 MSVVGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISNA 60
MSVVG+D+G QSCY+AVARAGGIETIANE+SDRCTP+ ISFG KNR+IG AAK+Q I++A
Sbjct: 1 MSVVGLDVGSQSCYIAVARAGGIETIANEFSDRCTPSVISFGSKNRTIGVAAKNQQITHA 60
Query: 61 KNTVQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTAM 120
NTV FKRFHGRAF+DPF++ EK NL+YD+V L G GIKV YM EE F+ EQ+TAM
Sbjct: 61 NNTVSNFKRFHGRAFNDPFIQKEKENLSYDLVPLKNGGVGIKVMYMGEEHLFSVEQITAM 120
Query: 121 LLSKLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVALA 180
LL+KLKETAE+ LKKPV DCV+SVP F+TDAERRSV+DA QI GLNCLRLMN+ TAVAL
Sbjct: 121 LLTKLKETAENSLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMNDMTAVALN 180
Query: 181 YGIYKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVL 240
YGIYKQDLP+L+EKPR VVFVDMGHSA+QVS CAFN+GKLKVL TAFD LGG+ FDE L
Sbjct: 181 YGIYKQDLPSLDEKPRIVVFVDMGHSAFQVSACAFNKGKLKVLGTAFDPFLGGKNFDEKL 240
Query: 241 VNHFCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMNDVDVSGT 300
V HFC EF KYKLD KSKIRALLRL QECEKLKKLMS+N++DLPL+IECFMND DVSG
Sbjct: 241 VEHFCAEFKTKYKLDAKSKIRALLRLYQECEKLKKLMSSNSTDLPLNIECFMNDKDVSGK 300
Query: 301 MNRGKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEKISKFFGK 360
MNR +F E+C +LL ++E PL S+LEQT LK ED+ AVEIVGGATRIPAVKE+I+KFFGK
Sbjct: 301 MNRSQFEELCAELLQKIEVPLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAKFFGK 360
Query: 361 ELSTTLNADEAVTRGCALQCAILSPAFKVREFSITDVVPYPISLRWNSPAEEGSSDCEVF 420
++STTLNADEAV RGCALQCAILSPAFKVREFS+TD VP+PISL WN +E+ EVF
Sbjct: 361 DISTTLNADEAVARGCALQCAILSPAFKVREFSVTDAVPFPISLIWNHDSEDTEGVHEVF 420
Query: 421 SKNHAAPFSKVLTFYRKEPFTLEAYYSSPQDLPYPDPAIAQFSVQKVTPQSDGSSSKVKV 480
S+NHAAPFSKVLTF R+ PF LEA+YS PQ +PYP+ I +F VQ V+ Q DG S+VKV
Sbjct: 421 SRNHAAPFSKVLTFLRRGPFELEAFYSDPQGVPYPEAKIGRFVVQNVSAQKDGEKSRVKV 480
Query: 481 KVRVNVHGIFSVSSASLVEVHKSEENEEPMETD---------QNAKEEEKMQVDQEE--- 528
KVRVN HGIF++S+AS+VE +EENE E D +N ++ +Q D E
Sbjct: 481 KVRVNTHGIFTISTASMVEKVPTEENEMSSEADMECLNQRPPENPDTDKNVQQDNSEAGT 540
Query: 529 -PHVEEQQQQT---PAENKAESEEMETSQAG-SKDKKMDQPPQAKKAKVKTSTVDLPIEN 583
P V+ QQT P + SEE + A + +KK+DQPP+AKK K+K V+LPIE
Sbjct: 541 QPQVQTDAQQTSQSPPSPELTSEENKIPDADKANEKKVDQPPEAKKPKIKVVNVELPIEA 600
Query: 584 QLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAKNAVEEYVYEMRDKLSGEYEKFVSED 643
L+WQ+ +++LN+YIE EGKMIMQDKLEKERNDAKNAVEEYVYE RDKL G YEKF+ E
Sbjct: 601 NLVWQLGKDLLNMYIETEGKMIMQDKLEKERNDAKNAVEEYVYEFRDKLCGPYEKFICEQ 660
Query: 644 DRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKNLGQPIKIRFQESEERPKLFEELG 703
D +F L +TE+WLYE+GEDQ KQ YVDKL EL +G P+K+RFQE+EERPK+FEELG
Sbjct: 661 DHQNFLRLLTETEDWLYEEGEDQAKQAYVDKLEELMKIGTPVKVRFQEAEERPKMFEELG 720
Query: 704 KQIQQYMKIISSFKNKEDQYDHLDAADMTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVV 763
+++Q Y KI + F+NK+++Y+H+D ++M KVEKS NE MEWMNN +N Q K+SL DPVV
Sbjct: 721 QRLQHYAKIAADFRNKDEKYNHIDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLDQDPVV 780
Query: 764 KSKEIEAKIKELTSTCSPIISKPKPKVEPPKEEQKNAEQNGP 805
+++EI+ KIKEL +TC P++++PKPK+E PK E+ NGP
Sbjct: 781 RAQEIKTKIKELNNTCEPVVTQPKPKIESPKLER---TPNGP 819
>gi|195976805 hypoxia up-regulated 1 precursor [Homo sapiens]
Length = 999
Score = 314 bits (805), Expect = 2e-85
Identities = 257/939 (27%), Positives = 425/939 (45%), Gaps = 116/939 (12%)
Query: 1 MSVVGIDLGFQSCYVAVARAG-GIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISN 59
++V+ +DLG +S VA+ + G +E + N+ S R TP ++ R G +A S I N
Sbjct: 33 LAVMSVDLGSESMKVAIVKPGVPMEIVLNKESRRKTPVIVTLKENERFFGDSAASMAIKN 92
Query: 60 AKNTVQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTA 119
K T++ F+ G+ +P V ++ + + + + F+ E+V
Sbjct: 93 PKATLRYFQHLLGKQADNPHVALYQARFPEHELTFDPQRQTVHFQ-ISSQLQFSPEEVLG 151
Query: 120 MLLSKLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVAL 179
M+L+ + AE ++P+ D V++VP F+ AERR+V+ A ++AGL L+L+N+ TA AL
Sbjct: 152 MVLNYSRSLAEDFAEQPIKDAVITVPVFFNQAERRAVLQAARMAGLKVLQLINDNTATAL 211
Query: 180 AYGIYKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGK---------LKVLATAFDTT 230
+YG++++ + +N++F DMG + ++ + K L++ FD T
Sbjct: 212 SYGVFRR--KDINTTAQNIMFYDMGSGSTVCTIVTYQMVKTKEAGMQPQLQIRGVGFDRT 269
Query: 231 LGGRKFD----EVLVNHFCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPL 286
LGG + + E L F E+ + D++ RA+ +L +E +LK ++SANA D
Sbjct: 270 LGGLEMELRLRERLAGLFNEQRKGQRAKDVRENPRAMAKLLREANRLKTVLSANA-DHMA 328
Query: 287 SIECFMNDVDVSGTMNRGKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATR 346
IE M+DVD + R +F E+C DL RV P++ L+ ++ ++I V +VGGATR
Sbjct: 329 QIEGLMDDVDFKAKVTRVEFEELCADLFERVPGPVQQALQSAEMSLDEIEQVILVGGATR 388
Query: 347 IPAVKEKISKFFGK-ELSTTLNADEAVTRGCALQCAILSPAFKVREFSITDVVPYPISLR 405
+P V+E + K GK EL +NADEA G Q A LS AFKV+ F + D V YPI +
Sbjct: 389 VPRVQEVLLKAVGKEELGKNINADEAAAMGAVYQAAALSKAFKVKPFVVRDAVVYPILVE 448
Query: 406 WNSPAEE-------GSSDCEVFSKNHAAPFSKVLTFYR-KEPFTLEAYYSSPQDLPYPDP 457
+ EE + +FS+ P KV+TF R F Y DL + P
Sbjct: 449 FTREVEEEPGIHSLKHNKRVLFSRMGPYPQRKVITFNRYSHDFNFHINYG---DLGFLGP 505
Query: 458 A-IAQFSVQKVT------------PQSDGSSSKVKVKVRVNVHGIFSVSSA-----SLVE 499
+ F Q +T D S +K ++ G+ S+ +LVE
Sbjct: 506 EDLRVFGSQNLTTVKLKGVGDSFKKYPDYESKGIKAHFNLDESGVLSLDRVESVFETLVE 565
Query: 500 VHKSEEN------------------------------EEPMETDQNAKEEEKMQV---DQ 526
EE+ EE + +K+E QV ++
Sbjct: 566 DSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDTVQEEEESPAEGSKDEPGEQVELKEE 625
Query: 527 EEPHVEEQQQQTPAENK----------AESEEMETSQAGSKDKKMD-------------- 562
E VE+ Q P E K E E + S+A +K +
Sbjct: 626 AEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDKSEAQKPSEKAEAGPEGVAPAPEGEK 685
Query: 563 -QPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAKNAV 621
Q P K+ V+ V+L + + L + + L ++ + ++D ++ER A N++
Sbjct: 686 KQKPARKRRMVEEIGVELVVLD--LPDLPEDKLAQSVQKLQDLTLRDLEKQEREKAANSL 743
Query: 622 EEYVYEMRDKL-SGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKN 680
E +++E +DKL EY++ +E+ R + KL WL ++G + +KLAEL+
Sbjct: 744 EAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAASTWLEDEGVGATTVMLKEKLAELRK 803
Query: 681 LGQPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAADMTKVEKSTNE 740
L Q + R +E ++ P+ L + + + + +MT +EK NE
Sbjct: 804 LCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGARLIPEMDQIFTEVEMTTLEKVINE 863
Query: 741 AMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKELTSTCSPIISKPKPKVEPPKEEQKNA 800
W N L Q K T PV+ SK+IEAK+ L +++K K P+ + KN
Sbjct: 864 TWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDREVQYLLNKAKFTKPRPRPKDKNG 923
Query: 801 EQ-----NGPVDGQGDNPGPQAAEQGTDTAVPSDSDKKL 834
+ N QG+ P A + T+ A P +K+
Sbjct: 924 TRAEPPLNASASDQGEKVIPPAGQ--TEDAEPISEPEKV 960
>gi|5453832 hypoxia up-regulated 1 precursor [Homo sapiens]
Length = 999
Score = 314 bits (805), Expect = 2e-85
Identities = 257/939 (27%), Positives = 425/939 (45%), Gaps = 116/939 (12%)
Query: 1 MSVVGIDLGFQSCYVAVARAG-GIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISN 59
++V+ +DLG +S VA+ + G +E + N+ S R TP ++ R G +A S I N
Sbjct: 33 LAVMSVDLGSESMKVAIVKPGVPMEIVLNKESRRKTPVIVTLKENERFFGDSAASMAIKN 92
Query: 60 AKNTVQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTA 119
K T++ F+ G+ +P V ++ + + + + F+ E+V
Sbjct: 93 PKATLRYFQHLLGKQADNPHVALYQARFPEHELTFDPQRQTVHFQ-ISSQLQFSPEEVLG 151
Query: 120 MLLSKLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVAL 179
M+L+ + AE ++P+ D V++VP F+ AERR+V+ A ++AGL L+L+N+ TA AL
Sbjct: 152 MVLNYSRSLAEDFAEQPIKDAVITVPVFFNQAERRAVLQAARMAGLKVLQLINDNTATAL 211
Query: 180 AYGIYKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGK---------LKVLATAFDTT 230
+YG++++ + +N++F DMG + ++ + K L++ FD T
Sbjct: 212 SYGVFRR--KDINTTAQNIMFYDMGSGSTVCTIVTYQMVKTKEAGMQPQLQIRGVGFDRT 269
Query: 231 LGGRKFD----EVLVNHFCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPL 286
LGG + + E L F E+ + D++ RA+ +L +E +LK ++SANA D
Sbjct: 270 LGGLEMELRLRERLAGLFNEQRKGQRAKDVRENPRAMAKLLREANRLKTVLSANA-DHMA 328
Query: 287 SIECFMNDVDVSGTMNRGKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATR 346
IE M+DVD + R +F E+C DL RV P++ L+ ++ ++I V +VGGATR
Sbjct: 329 QIEGLMDDVDFKAKVTRVEFEELCADLFERVPGPVQQALQSAEMSLDEIEQVILVGGATR 388
Query: 347 IPAVKEKISKFFGK-ELSTTLNADEAVTRGCALQCAILSPAFKVREFSITDVVPYPISLR 405
+P V+E + K GK EL +NADEA G Q A LS AFKV+ F + D V YPI +
Sbjct: 389 VPRVQEVLLKAVGKEELGKNINADEAAAMGAVYQAAALSKAFKVKPFVVRDAVVYPILVE 448
Query: 406 WNSPAEE-------GSSDCEVFSKNHAAPFSKVLTFYR-KEPFTLEAYYSSPQDLPYPDP 457
+ EE + +FS+ P KV+TF R F Y DL + P
Sbjct: 449 FTREVEEEPGIHSLKHNKRVLFSRMGPYPQRKVITFNRYSHDFNFHINYG---DLGFLGP 505
Query: 458 A-IAQFSVQKVT------------PQSDGSSSKVKVKVRVNVHGIFSVSSA-----SLVE 499
+ F Q +T D S +K ++ G+ S+ +LVE
Sbjct: 506 EDLRVFGSQNLTTVKLKGVGDSFKKYPDYESKGIKAHFNLDESGVLSLDRVESVFETLVE 565
Query: 500 VHKSEEN------------------------------EEPMETDQNAKEEEKMQV---DQ 526
EE+ EE + +K+E QV ++
Sbjct: 566 DSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDTVQEEEESPAEGSKDEPGEQVELKEE 625
Query: 527 EEPHVEEQQQQTPAENK----------AESEEMETSQAGSKDKKMD-------------- 562
E VE+ Q P E K E E + S+A +K +
Sbjct: 626 AEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDKSEAQKPSEKAEAGPEGVAPAPEGEK 685
Query: 563 -QPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAKNAV 621
Q P K+ V+ V+L + + L + + L ++ + ++D ++ER A N++
Sbjct: 686 KQKPARKRRMVEEIGVELVVLD--LPDLPEDKLAQSVQKLQDLTLRDLEKQEREKAANSL 743
Query: 622 EEYVYEMRDKL-SGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKN 680
E +++E +DKL EY++ +E+ R + KL WL ++G + +KLAEL+
Sbjct: 744 EAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAASTWLEDEGVGATTVMLKEKLAELRK 803
Query: 681 LGQPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAADMTKVEKSTNE 740
L Q + R +E ++ P+ L + + + + +MT +EK NE
Sbjct: 804 LCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGARLIPEMDQIFTEVEMTTLEKVINE 863
Query: 741 AMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKELTSTCSPIISKPKPKVEPPKEEQKNA 800
W N L Q K T PV+ SK+IEAK+ L +++K K P+ + KN
Sbjct: 864 TWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDREVQYLLNKAKFTKPRPRPKDKNG 923
Query: 801 EQ-----NGPVDGQGDNPGPQAAEQGTDTAVPSDSDKKL 834
+ N QG+ P A + T+ A P +K+
Sbjct: 924 TRAEPPLNASASDQGEKVIPPAGQ--TEDAEPISEPEKV 960
>gi|34419635 heat shock 70kDa protein 6 (HSP70B') [Homo sapiens]
Length = 643
Score = 301 bits (770), Expect = 2e-81
Identities = 191/581 (32%), Positives = 310/581 (53%), Gaps = 27/581 (4%)
Query: 4 VGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISNAKNT 63
VGIDLG V V + G +E +AN+ +R TP+ ++F R +G AAKSQ N NT
Sbjct: 9 VGIDLGTTYSCVGVFQQGRVEILANDQGNRTTPSYVAFTDTERLVGDAAKSQAALNPHNT 68
Query: 64 VQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTAMLLS 123
V KR GR F+D V+++ + + +V G ++V Y E++ F E++++M+LS
Sbjct: 69 VFDAKRLIGRKFADTTVQSDMKHWPFRVVS-EGGKPKVRVCYRGEDKTFYPEEISSMVLS 127
Query: 124 KLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVALAYGI 183
K+KETAE+ L +PV V++VP ++ D++R++ DA IAGLN LR++NE TA A+AYG+
Sbjct: 128 KMKETAEAYLGQPVKHAVITVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGL 187
Query: 184 YKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVLVNH 243
++ RNV+ D+G + VSV + + G +V ATA DT LGG FD LVNH
Sbjct: 188 DRRG-----AGERNVLIFDLGGGTFDVSVLSIDAGVFEVKATAGDTHLGGEDFDNRLVNH 242
Query: 244 FCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMNDVDVSGTMNR 303
F EEF +K+ D+ RAL RL CE+ K+ +S +++ L I+ VD ++ R
Sbjct: 243 FMEEFRRKHGKDLSGNKRALRRLRTACERAKRTLS-SSTQATLEIDSLFEGVDFYTSITR 301
Query: 304 GKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEKISKFF-GKEL 362
+F E+C+DL P+ L KL K I+ V +VGG+TRIP V++ + FF GKEL
Sbjct: 302 ARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDVVLVGGSTRIPKVQKLLQDFFNGKEL 361
Query: 363 STTLNADEAVTRGCALQCAIL--SPAFKVREFSITDVVPYPISLRWNSPAEEGSSDCEVF 420
+ ++N DEAV G A+Q A+L KV++ + DV P + L G +
Sbjct: 362 NKSINPDEAVAYGAAVQAAVLMGDKCEKVQDLLLLDVAPLSLGLE-----TAGGVMTTLI 416
Query: 421 SKNHAAPFSKVLTFYR---KEPFTLEAYYSSPQDLPYPDPAIAQFSVQKVTPQSDGSSSK 477
+N P + TF +P Y + + + + +F + + P G +
Sbjct: 417 QRNATIPTKQTQTFTTYSDNQPGVFIQVYEGERAMTKDNNLLGRFELSGIPPAPRG-VPQ 475
Query: 478 VKVKVRVNVHGIFSVSSASLVEVHKSEENEEPMETDQN--AKEEEKMQVDQEEPHV---E 532
++V ++ +GI SV++ + + N+ + D+ +KEE + V + E + E
Sbjct: 476 IEVTFDIDANGILSVTA---TDRSTGKANKITITNDKGRLSKEEVERMVHEAEQYKAEDE 532
Query: 533 EQQQQTPAENKAESEEMETSQAGSKDKKMDQPPQAKKAKVK 573
Q+ + A+N E+ + ++ D+ P+ + K++
Sbjct: 533 AQRDRVAAKNSLEAHVFHVKGSLQEESLRDKIPEEDRRKMQ 573
>gi|167466173 heat shock 70kDa protein 1B [Homo sapiens]
Length = 641
Score = 294 bits (752), Expect = 3e-79
Identities = 188/582 (32%), Positives = 309/582 (53%), Gaps = 27/582 (4%)
Query: 2 SVVGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISNAK 61
+ +GIDLG V V + G +E IAN+ +R TP+ ++F R IG AAK+QV N +
Sbjct: 5 AAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQ 64
Query: 62 NTVQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTAML 121
NTV KR GR F DP V+++ + + ++ ++V+Y E + F E++++M+
Sbjct: 65 NTVFDAKRLIGRKFGDPVVQSDMKHWPFQVIN-DGDKPKVQVSYKGETKAFYPEEISSMV 123
Query: 122 LSKLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVALAY 181
L+K+KE AE+ L PV + V++VP ++ D++R++ DA IAGLN LR++NE TA A+AY
Sbjct: 124 LTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAY 183
Query: 182 GIYKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVLV 241
G L + RNV+ D+G + VS+ + G +V ATA DT LGG FD LV
Sbjct: 184 G-----LDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLV 238
Query: 242 NHFCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMNDVDVSGTM 301
NHF EEF +K+K DI RA+ RL CE+ K+ +S +++ L I+ +D ++
Sbjct: 239 NHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLS-SSTQASLEIDSLFEGIDFYTSI 297
Query: 302 NRGKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEKISKFF-GK 360
R +F E+C+DL P+ L KL K I+ + +VGG+TRIP V++ + FF G+
Sbjct: 298 TRARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGR 357
Query: 361 ELSTTLNADEAVTRGCALQCAIL--SPAFKVREFSITDVVPYPISLRWNSPAEEGSSDCE 418
+L+ ++N DEAV G A+Q AIL + V++ + DV P + L G
Sbjct: 358 DLNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLE-----TAGGVMTA 412
Query: 419 VFSKNHAAPFSKV---LTFYRKEPFTLEAYYSSPQDLPYPDPAIAQFSVQKVTPQSDGSS 475
+ +N P + T+ +P L Y + + + + +F + + P G
Sbjct: 413 LIKRNSTIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPRG-V 471
Query: 476 SKVKVKVRVNVHGIFSVSSASLVEVHKSEENEEPMETDQN--AKEEEKMQVDQEEPHVEE 533
+++V ++ +GI +V++ + + N+ + D+ +KEE + V + E + E
Sbjct: 472 PQIEVTFDIDANGILNVTA---TDKSTGKANKITITNDKGRLSKEEIERMVQEAEKYKAE 528
Query: 534 ---QQQQTPAENKAESEEMETSQAGSKDKKMDQPPQAKKAKV 572
Q+++ A+N ES A + + +A K KV
Sbjct: 529 DEVQRERVSAKNALESYAFNMKSAVEDEGLKGKISEADKKKV 570
Score = 42.4 bits (98), Expect = 0.002
Identities = 26/99 (26%), Positives = 50/99 (50%), Gaps = 2/99 (2%)
Query: 588 QIDREMLNLYIENEGKMIMQDKLEKERNDAKNAVEEYVYEMRDKLSGEYEK-FVSEDDRN 646
++ +E + ++ K +D++++ER AKNA+E Y + M+ + E K +SE D+
Sbjct: 509 RLSKEEIERMVQEAEKYKAEDEVQRERVSAKNALESYAFNMKSAVEDEGLKGKISEADKK 568
Query: 647 SFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKNLGQPI 685
K ++ +WL + K + K EL+ + PI
Sbjct: 569 KVLDKCQEVISWL-DANTLAEKDEFEHKRKELEQVCNPI 606
Score = 31.6 bits (70), Expect = 3.2
Identities = 31/133 (23%), Positives = 49/133 (36%), Gaps = 21/133 (15%)
Query: 688 RFQESEERPKLFEELGKQ-------IQQYMKIISSFKNKEDQYDHLDAADMTKVEKSTNE 740
R + E+ K +E+ ++ ++ Y + S E + AD KV E
Sbjct: 517 RMVQEAEKYKAEDEVQRERVSAKNALESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQE 576
Query: 741 AMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKELTSTCSPIISKPKPKVEPPKEEQKNA 800
+ W++ + + + E E K KEL C+PIIS P A
Sbjct: 577 VISWLD------------ANTLAEKDEFEHKRKELEQVCNPIISGLYQGAGGPGPGGFGA 624
Query: 801 EQNGPVDGQGDNP 813
+ GP G G P
Sbjct: 625 Q--GPKGGSGSGP 635
>gi|194248072 heat shock 70kDa protein 1A [Homo sapiens]
Length = 641
Score = 294 bits (752), Expect = 3e-79
Identities = 188/582 (32%), Positives = 309/582 (53%), Gaps = 27/582 (4%)
Query: 2 SVVGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISNAK 61
+ +GIDLG V V + G +E IAN+ +R TP+ ++F R IG AAK+QV N +
Sbjct: 5 AAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQ 64
Query: 62 NTVQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTAML 121
NTV KR GR F DP V+++ + + ++ ++V+Y E + F E++++M+
Sbjct: 65 NTVFDAKRLIGRKFGDPVVQSDMKHWPFQVIN-DGDKPKVQVSYKGETKAFYPEEISSMV 123
Query: 122 LSKLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVALAY 181
L+K+KE AE+ L PV + V++VP ++ D++R++ DA IAGLN LR++NE TA A+AY
Sbjct: 124 LTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAY 183
Query: 182 GIYKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVLV 241
G L + RNV+ D+G + VS+ + G +V ATA DT LGG FD LV
Sbjct: 184 G-----LDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLV 238
Query: 242 NHFCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMNDVDVSGTM 301
NHF EEF +K+K DI RA+ RL CE+ K+ +S +++ L I+ +D ++
Sbjct: 239 NHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLS-SSTQASLEIDSLFEGIDFYTSI 297
Query: 302 NRGKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEKISKFF-GK 360
R +F E+C+DL P+ L KL K I+ + +VGG+TRIP V++ + FF G+
Sbjct: 298 TRARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGR 357
Query: 361 ELSTTLNADEAVTRGCALQCAIL--SPAFKVREFSITDVVPYPISLRWNSPAEEGSSDCE 418
+L+ ++N DEAV G A+Q AIL + V++ + DV P + L G
Sbjct: 358 DLNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLE-----TAGGVMTA 412
Query: 419 VFSKNHAAPFSKV---LTFYRKEPFTLEAYYSSPQDLPYPDPAIAQFSVQKVTPQSDGSS 475
+ +N P + T+ +P L Y + + + + +F + + P G
Sbjct: 413 LIKRNSTIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPRG-V 471
Query: 476 SKVKVKVRVNVHGIFSVSSASLVEVHKSEENEEPMETDQN--AKEEEKMQVDQEEPHVEE 533
+++V ++ +GI +V++ + + N+ + D+ +KEE + V + E + E
Sbjct: 472 PQIEVTFDIDANGILNVTA---TDKSTGKANKITITNDKGRLSKEEIERMVQEAEKYKAE 528
Query: 534 ---QQQQTPAENKAESEEMETSQAGSKDKKMDQPPQAKKAKV 572
Q+++ A+N ES A + + +A K KV
Sbjct: 529 DEVQRERVSAKNALESYAFNMKSAVEDEGLKGKISEADKKKV 570
Score = 42.4 bits (98), Expect = 0.002
Identities = 26/99 (26%), Positives = 50/99 (50%), Gaps = 2/99 (2%)
Query: 588 QIDREMLNLYIENEGKMIMQDKLEKERNDAKNAVEEYVYEMRDKLSGEYEK-FVSEDDRN 646
++ +E + ++ K +D++++ER AKNA+E Y + M+ + E K +SE D+
Sbjct: 509 RLSKEEIERMVQEAEKYKAEDEVQRERVSAKNALESYAFNMKSAVEDEGLKGKISEADKK 568
Query: 647 SFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKNLGQPI 685
K ++ +WL + K + K EL+ + PI
Sbjct: 569 KVLDKCQEVISWL-DANTLAEKDEFEHKRKELEQVCNPI 606
Score = 31.6 bits (70), Expect = 3.2
Identities = 31/133 (23%), Positives = 49/133 (36%), Gaps = 21/133 (15%)
Query: 688 RFQESEERPKLFEELGKQ-------IQQYMKIISSFKNKEDQYDHLDAADMTKVEKSTNE 740
R + E+ K +E+ ++ ++ Y + S E + AD KV E
Sbjct: 517 RMVQEAEKYKAEDEVQRERVSAKNALESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQE 576
Query: 741 AMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKELTSTCSPIISKPKPKVEPPKEEQKNA 800
+ W++ + + + E E K KEL C+PIIS P A
Sbjct: 577 VISWLD------------ANTLAEKDEFEHKRKELEQVCNPIISGLYQGAGGPGPGGFGA 624
Query: 801 EQNGPVDGQGDNP 813
+ GP G G P
Sbjct: 625 Q--GPKGGSGSGP 635
>gi|124256496 heat shock 70kDa protein 1-like [Homo sapiens]
Length = 641
Score = 293 bits (749), Expect = 6e-79
Identities = 189/580 (32%), Positives = 312/580 (53%), Gaps = 27/580 (4%)
Query: 4 VGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISNAKNT 63
+GIDLG V V + G +E IAN+ +R TP+ ++F R IG AAK+QV N +NT
Sbjct: 9 IGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPQNT 68
Query: 64 VQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTAMLLS 123
V KR GR F+DP V+A+ + ++ G + V+Y E + F E++++M+L+
Sbjct: 69 VFDAKRLIGRKFNDPVVQADMKLWPFQVIN-EGGKPKVLVSYKGENKAFYPEEISSMVLT 127
Query: 124 KLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVALAYGI 183
KLKETAE+ L PV + V++VP ++ D++R++ DA IAGLN LR++NE TA A+AYG+
Sbjct: 128 KLKETAEAFLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGL 187
Query: 184 YKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVLVNH 243
K + R+V+ D+G + VS+ + G +V ATA DT LGG FD LV+H
Sbjct: 188 DKGG-----QGERHVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVSH 242
Query: 244 FCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMNDVDVSGTMNR 303
F EEF +K+K DI RA+ RL CE+ K+ +S +++ L I+ +D ++ R
Sbjct: 243 FVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLS-SSTQANLEIDSLYEGIDFYTSITR 301
Query: 304 GKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEKISKFF-GKEL 362
+F E+C DL P+ L K+ K I+ + +VGG+TRIP V+ + +F G++L
Sbjct: 302 ARFEELCADLFRGTLEPVEKALRDAKMDKAKIHDIVLVGGSTRIPKVQRLLQDYFNGRDL 361
Query: 363 STTLNADEAVTRGCALQCAIL--SPAFKVREFSITDVVPYPISLRWNSPAEEGSSDCEVF 420
+ ++N DEAV G A+Q AIL + KV++ + DV P + L G +
Sbjct: 362 NKSINPDEAVAYGAAVQAAILMGDKSEKVQDLLLLDVAPLSLGLE-----TAGGVMTALI 416
Query: 421 SKNHAAPFSKV---LTFYRKEPFTLEAYYSSPQDLPYPDPAIAQFSVQKVTPQSDGSSSK 477
+N P + T+ +P L Y + + + + +F + + P G +
Sbjct: 417 KRNSTIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFDLTGIPPAPRG-VPQ 475
Query: 478 VKVKVRVNVHGIFSVSSASLVEVHKSEENEEPMETDQN--AKEE-EKMQVDQEEPHVEE- 533
++V ++ +GI +V++ + + N+ + D+ +KEE E+M +D E+ E+
Sbjct: 476 IEVTFDIDANGILNVTA---TDKSTGKVNKITITNDKGRLSKEEIERMVLDAEKYKAEDE 532
Query: 534 -QQQQTPAENKAESEEMETSQAGSKDKKMDQPPQAKKAKV 572
Q+++ A+N ES S + + ++ K K+
Sbjct: 533 VQREKIAAKNALESYAFNMKSVVSDEGLKGKISESDKNKI 572
Score = 44.3 bits (103), Expect = 5e-04
Identities = 28/99 (28%), Positives = 52/99 (52%), Gaps = 2/99 (2%)
Query: 588 QIDREMLNLYIENEGKMIMQDKLEKERNDAKNAVEEYVYEMRDKLSGEYEK-FVSEDDRN 646
++ +E + + + K +D++++E+ AKNA+E Y + M+ +S E K +SE D+N
Sbjct: 511 RLSKEEIERMVLDAEKYKAEDEVQREKIAAKNALESYAFNMKSVVSDEGLKGKISESDKN 570
Query: 647 SFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKNLGQPI 685
K + +WL E + K + K EL+ + PI
Sbjct: 571 KILDKCNELLSWL-EVNQLAEKDEFDHKRKELEQMCNPI 608
Score = 32.3 bits (72), Expect = 1.9
Identities = 22/100 (22%), Positives = 43/100 (43%), Gaps = 14/100 (14%)
Query: 686 KIRFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAADMTKVEKSTNEAMEWM 745
K + ++ +R K+ + ++ Y + S + E + +D K+ NE + W
Sbjct: 526 KYKAEDEVQREKIAAK--NALESYAFNMKSVVSDEGLKGKISESDKNKILDKCNELLSW- 582
Query: 746 NNKLNLQNKQSLTMDPVVKSKEIEAKIKELTSTCSPIISK 785
L ++ + + E + K KEL C+PII+K
Sbjct: 583 -----------LEVNQLAEKDEFDHKRKELEQMCNPIITK 611
>gi|5729877 heat shock 70kDa protein 8 isoform 1 [Homo sapiens]
Length = 646
Score = 288 bits (738), Expect = 1e-77
Identities = 199/623 (31%), Positives = 322/623 (51%), Gaps = 36/623 (5%)
Query: 4 VGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISNAKNT 63
VGIDLG V V + G +E IAN+ +R TP+ ++F R IG AAK+QV N NT
Sbjct: 7 VGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNT 66
Query: 64 VQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTAMLLS 123
V KR GR F D V+++ + + +V G ++V Y E ++F E+V++M+L+
Sbjct: 67 VFDAKRLIGRRFDDAVVQSDMKHWPFMVVN-DAGRPKVQVEYKGETKSFYPEEVSSMVLT 125
Query: 124 KLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVALAYGI 183
K+KE AE+ L K V + VV+VP ++ D++R++ DA IAGLN LR++NE TA A+AYG+
Sbjct: 126 KMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGL 185
Query: 184 YKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVLVNH 243
K+ RNV+ D+G + VS+ G +V +TA DT LGG FD +VNH
Sbjct: 186 DKK-----VGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNH 240
Query: 244 FCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMNDVDVSGTMNR 303
F EF +K+K DI RA+ RL CE+ K+ +S +++ + I+ +D ++ R
Sbjct: 241 FIAEFKRKHKKDISENKRAVRRLRTACERAKRTLS-SSTQASIEIDSLYEGIDFYTSITR 299
Query: 304 GKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEKISKFF-GKEL 362
+F E+ DL P+ L KL K I+ + +VGG+TRIP +++ + FF GKEL
Sbjct: 300 ARFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKEL 359
Query: 363 STTLNADEAVTRGCALQCAILS--PAFKVREFSITDVVPYPISLRWNSPAEEGSSDCEVF 420
+ ++N DEAV G A+Q AILS + V++ + DV P + + G +
Sbjct: 360 NKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIE-----TAGGVMTVLI 414
Query: 421 SKNHAAPFSKVLTFYR---KEPFTLEAYYSSPQDLPYPDPAIAQFSVQKVTPQSDGSSSK 477
+N P + TF +P L Y + + + + +F + + P G +
Sbjct: 415 KRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRG-VPQ 473
Query: 478 VKVKVRVNVHGIFSVSSASLVEVHKSEENEEPMETDQN--AKEEEKMQVDQEEPHV---E 532
++V ++ +GI +VS+ V+ +EN+ + D+ +KE+ + V + E + E
Sbjct: 474 IEVTFDIDANGILNVSA---VDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDE 530
Query: 533 EQQQQTPAENKAESEEMETSQAGSKDKKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDRE 592
+Q+ + ++N ES +K + K K+ L N+++ +D+
Sbjct: 531 KQRDKVSSKNSLESYAFNMKATVEDEKLQGKINDEDKQKI------LDKCNEIINWLDK- 583
Query: 593 MLNLYIENEGKMIMQDKLEKERN 615
N E E Q +LEK N
Sbjct: 584 --NQTAEKEEFEHQQKELEKVCN 604
Score = 39.3 bits (90), Expect = 0.015
Identities = 22/110 (20%), Positives = 56/110 (50%), Gaps = 10/110 (9%)
Query: 588 QIDREMLNLYIENEGKMIMQDKLEKERNDAKNAVEEYVYEMR-----DKLSGEYEKFVSE 642
++ +E + ++ K +D+ ++++ +KN++E Y + M+ +KL G+ +++
Sbjct: 509 RLSKEDIERMVQEAEKYKAEDEKQRDKVSSKNSLESYAFNMKATVEDEKLQGK----IND 564
Query: 643 DDRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKNLGQPIKIRFQES 692
+D+ K + NWL + + K+ + + EL+ + PI + +S
Sbjct: 565 EDKQKILDKCNEIINWL-DKNQTAEKEEFEHQQKELEKVCNPIITKLYQS 613
Score = 31.6 bits (70), Expect = 3.2
Identities = 25/118 (21%), Positives = 50/118 (42%), Gaps = 12/118 (10%)
Query: 679 KNLGQPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAADMTKVEKST 738
K+ G+ KI + R E++ + +Q+ K + + + D+ ++ +
Sbjct: 493 KSTGKENKITITNDKGRLSK-EDIERMVQEAEKYKAEDEKQRDKVSSKNSLESYAFNMKA 551
Query: 739 NEAMEWMNNKLNLQNKQS-----------LTMDPVVKSKEIEAKIKELTSTCSPIISK 785
E + K+N ++KQ L + + +E E + KEL C+PII+K
Sbjct: 552 TVEDEKLQGKINDEDKQKILDKCNEIINWLDKNQTAEKEEFEHQQKELEKVCNPIITK 609
>gi|16507237 heat shock 70kDa protein 5 [Homo sapiens]
Length = 654
Score = 284 bits (727), Expect = 2e-76
Identities = 194/603 (32%), Positives = 316/603 (52%), Gaps = 44/603 (7%)
Query: 2 SVVGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISFGPKN-RSIGAAAKSQVISNA 60
+VVGIDLG V V + G +E IAN+ +R TP+ ++F P+ R IG AAK+Q+ SN
Sbjct: 29 TVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNP 88
Query: 61 KNTVQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYME------EERNFTT 114
+NTV KR GR ++DP V+ + L + +V+ T Y++ + + F
Sbjct: 89 ENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTK------PYIQVDIGGGQTKTFAP 142
Query: 115 EQVTAMLLSKLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNET 174
E+++AM+L+K+KETAE+ L K V VV+VP ++ DA+R++ DA IAGLN +R++NE
Sbjct: 143 EEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEP 202
Query: 175 TAVALAYGIYKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGR 234
TA A+AYG+ K+ E +N++ D+G + VS+ + G +V+AT DT LGG
Sbjct: 203 TAAAIAYGLDKR------EGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGE 256
Query: 235 KFDEVLVNHFCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMND 294
FD+ ++ HF + + KK D++ RA+ +L +E EK K+ +S+ + IE F
Sbjct: 257 DFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQ-HQARIEIESFYEG 315
Query: 295 VDVSGTMNRGKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEKI 354
D S T+ R KF E+ DL P++ VLE + LKK DI + +VGG+TRIP +++ +
Sbjct: 316 EDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLV 375
Query: 355 SKFF-GKELSTTLNADEAVTRGCALQCAILSPAFKVREFSITDVVPYPISLRWNSPAEEG 413
+FF GKE S +N DEAV G A+Q +LS + + DV P + + G
Sbjct: 376 KEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVCPLTLGIE-----TVG 430
Query: 414 SSDCEVFSKNHAAPFSKVLTFYR---KEPFTLEAYYSSPQDLPYPDPAIAQFSVQKVTPQ 470
++ +N P K F +P Y + L + + F + + P
Sbjct: 431 GVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPA 490
Query: 471 SDGSSSKVKVKVRVNVHGIFSVSSASLVEVHKSEENEEPMETDQN---AKEEEKMQVDQE 527
G +++V ++V+GI V++ + +N+ + DQN +E E+M D E
Sbjct: 491 PRG-VPQIEVTFEIDVNGILRVTAE---DKGTGNKNKITITNDQNRLTPEEIERMVNDAE 546
Query: 528 EPHVEEQQQQTPAENKAESEEMETS---QAGSKDKKMDQPPQAKKAKVKTSTVDLPIENQ 584
+ E+++ + + + E E S Q G K+K K + T++ +E +
Sbjct: 547 KFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKL-----GGKLSSEDKETMEKAVEEK 601
Query: 585 LLW 587
+ W
Sbjct: 602 IEW 604
Score = 47.4 bits (111), Expect = 6e-05
Identities = 32/113 (28%), Positives = 56/113 (49%), Gaps = 5/113 (4%)
Query: 592 EMLNLYIENEGKMIMQDKLEKERNDAKNAVEEYVYEMRDKLSGEYEKF---VSEDDRNSF 648
E + + + K +DK KER D +N +E Y Y +++++ G+ EK +S +D+ +
Sbjct: 536 EEIERMVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQI-GDKEKLGGKLSSEDKETM 594
Query: 649 TLKLEDTENWLYEDGEDQPKQVYVDKLAELKNLGQPIKIRFQESEERPKLFEE 701
+E+ WL E +D + + K EL+ + QPI + S P EE
Sbjct: 595 EKAVEEKIEWL-ESHQDADIEDFKAKKKELEEIVQPIISKLYGSAGPPPTGEE 646
Score = 35.4 bits (80), Expect = 0.22
Identities = 30/118 (25%), Positives = 54/118 (45%), Gaps = 14/118 (11%)
Query: 688 RFQESEERPKLFEELGKQIQQYM-KIISSFKNKEDQYDHLDAADMTKVEKSTNEAMEWMN 746
+F E +++ K + +++ Y + + +KE L + D +EK+ E +EW
Sbjct: 547 KFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEEKIEW-- 604
Query: 747 NKLNLQNKQSLTMDPVVKSKEIEAKIKELTSTCSPIISKPKPKV-EPPKEEQKNAEQN 803
L++ Q ++ + +AK KEL PIISK PP E+ AE++
Sbjct: 605 ----LESHQDADIE------DFKAKKKELEEIVQPIISKLYGSAGPPPTGEEDTAEKD 652
>gi|13676857 heat shock 70kDa protein 2 [Homo sapiens]
Length = 639
Score = 271 bits (692), Expect = 2e-72
Identities = 179/580 (30%), Positives = 298/580 (51%), Gaps = 25/580 (4%)
Query: 4 VGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISNAKNT 63
+GIDLG V V + G +E IAN+ +R TP+ ++F R IG AAK+QV N NT
Sbjct: 8 IGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNT 67
Query: 64 VQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTAMLLS 123
+ KR GR F D V+++ + + +V G ++V Y E + F E++++M+L+
Sbjct: 68 IFDAKRLIGRKFEDATVQSDMKHWPFRVVS-EGGKPKVQVEYKGETKTFFPEEISSMVLT 126
Query: 124 KLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVALAYGI 183
K+KE AE+ L V V++VP ++ D++R++ DA I GLN LR++NE TA A+AYG+
Sbjct: 127 KMKEIAEAYLGGKVHSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAAAIAYGL 186
Query: 184 YKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVLVNH 243
K+ E +NV+ D+G + VS+ G +V +TA DT LGG FD +V+H
Sbjct: 187 DKKGCAGGE---KNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVSH 243
Query: 244 FCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMNDVDVSGTMNR 303
EEF +K+K DI RA+ RL CE+ K+ +S +++ + I+ VD ++ R
Sbjct: 244 LAEEFKRKHKKDIGPNKRAVRRLRTACERAKRTLS-SSTQASIEIDSLYEGVDFYTSITR 302
Query: 304 GKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEKISKFF-GKEL 362
+F E+ DL P+ L KL K I + +VGG+TRIP +++ + FF GKEL
Sbjct: 303 ARFEELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGKEL 362
Query: 363 STTLNADEAVTRGCALQCAIL--SPAFKVREFSITDVVPYPISLRWNSPAEEGSSDCEVF 420
+ ++N DEAV G A+Q AIL + V++ + DV P + + G +
Sbjct: 363 NKSINPDEAVAYGAAVQAAILIGDKSENVQDLLLLDVTPLSLGIE-----TAGGVMTPLI 417
Query: 421 SKNHAAPFSKVLTFYR---KEPFTLEAYYSSPQDLPYPDPAIAQFSVQKVTPQSDGSSSK 477
+N P + TF + L Y + + + + +F + + P G +
Sbjct: 418 KRNTTIPTKQTQTFTTYSDNQSSVLVQVYEGERAMTKDNNLLGKFDLTGIPPAPRG-VPQ 476
Query: 478 VKVKVRVNVHGIFSVSSASLVEVHKSEENEEPMETDQN--AKEEEKMQVDQEEPHVEEQQ 535
++V ++ +GI +V++A + +EN+ + D+ +K++ V + E + E +
Sbjct: 477 IEVTFDIDANGILNVTAA---DKSTGKENKITITNDKGRLSKDDIDRMVQEAERYKSEDE 533
Query: 536 ---QQTPAENKAESEEMETSQAGSKDKKMDQPPQAKKAKV 572
+ A+N ES Q +K + + K K+
Sbjct: 534 ANRDRVAAKNALESYTYNIKQTVEDEKLRGKISEQDKNKI 573
Score = 44.3 bits (103), Expect = 5e-04
Identities = 25/99 (25%), Positives = 50/99 (50%), Gaps = 2/99 (2%)
Query: 588 QIDREMLNLYIENEGKMIMQDKLEKERNDAKNAVEEYVYEMRDKLSGE-YEKFVSEDDRN 646
++ ++ ++ ++ + +D+ ++R AKNA+E Y Y ++ + E +SE D+N
Sbjct: 512 RLSKDDIDRMVQEAERYKSEDEANRDRVAAKNALESYTYNIKQTVEDEKLRGKISEQDKN 571
Query: 647 SFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKNLGQPI 685
K ++ NWL + + K Y K EL+ + PI
Sbjct: 572 KILDKCQEVINWL-DRNQMAEKDEYEHKQKELERVCNPI 609
>gi|24234686 heat shock 70kDa protein 8 isoform 2 [Homo sapiens]
Length = 493
Score = 270 bits (689), Expect = 5e-72
Identities = 161/434 (37%), Positives = 244/434 (56%), Gaps = 15/434 (3%)
Query: 4 VGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISNAKNT 63
VGIDLG V V + G +E IAN+ +R TP+ ++F R IG AAK+QV N NT
Sbjct: 7 VGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNT 66
Query: 64 VQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTAMLLS 123
V KR GR F D V+++ + + +V G ++V Y E ++F E+V++M+L+
Sbjct: 67 VFDAKRLIGRRFDDAVVQSDMKHWPFMVVN-DAGRPKVQVEYKGETKSFYPEEVSSMVLT 125
Query: 124 KLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVALAYGI 183
K+KE AE+ L K V + VV+VP ++ D++R++ DA IAGLN LR++NE TA A+AYG+
Sbjct: 126 KMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGL 185
Query: 184 YKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVLVNH 243
K+ RNV+ D+G + VS+ G +V +TA DT LGG FD +VNH
Sbjct: 186 DKK-----VGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNH 240
Query: 244 FCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMNDVDVSGTMNR 303
F EF +K+K DI RA+ RL CE+ K+ +S +++ + I+ +D ++ R
Sbjct: 241 FIAEFKRKHKKDISENKRAVRRLRTACERAKRTLS-SSTQASIEIDSLYEGIDFYTSITR 299
Query: 304 GKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEKISKFF-GKEL 362
+F E+ DL P+ L KL K I+ + +VGG+TRIP +++ + FF GKEL
Sbjct: 300 ARFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKEL 359
Query: 363 STTLNADEAVTRGCALQCAILS--PAFKVREFSITDVVPYPISLRWNSPAEEGSSDCEVF 420
+ ++N DEAV G A+Q AILS + V++ + DV P + + G +
Sbjct: 360 NKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIE-----TAGGVMTVLI 414
Query: 421 SKNHAAPFSKVLTF 434
+N P + TF
Sbjct: 415 KRNTTIPTKQTQTF 428
>gi|24234688 heat shock 70kDa protein 9 precursor [Homo sapiens]
Length = 679
Score = 219 bits (558), Expect = 8e-57
Identities = 158/573 (27%), Positives = 277/573 (48%), Gaps = 39/573 (6%)
Query: 2 SVVGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISF-GPKNRSIGAAAKSQVISNA 60
+VVGIDLG + VAV + + N R TP+ ++F R +G AK Q ++N
Sbjct: 54 AVVGIDLGTTNSCVAVMEGKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQAVTNP 113
Query: 61 KNTVQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTAM 120
NT KR GR + DP V+ + N+ + IV+ G ++ + ++ Q+ A
Sbjct: 114 NNTFYATKRLIGRRYDDPEVQKDIKNVPFKIVRASNGDAWVEA----HGKLYSPSQIGAF 169
Query: 121 LLSKLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVALA 180
+L K+KETAE+ L + V++VP ++ D++R++ DA QI+GLN LR++NE TA ALA
Sbjct: 170 VLMKMKETAENYLGHTAKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAAALA 229
Query: 181 YGIYKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVL 240
YG+ K + + + D+G + +S+ +G +V +T DT LGG FD+ L
Sbjct: 230 YGLDKSE-------DKVIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTFLGGEDFDQAL 282
Query: 241 VNHFCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANAS---DLPLSIECFMNDVDV 297
+ H +EF ++ +D+ AL R+ + EK K +S++ +LP +
Sbjct: 283 LRHIVKEFKRETGVDLTKDNMALQRVREAAEKAKCELSSSVQTDINLPYLTMDSSGPKHL 342
Query: 298 SGTMNRGKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEKISKF 357
+ + R +F + DL+ R P + ++ ++ K DI V +VGG TR+P V++ +
Sbjct: 343 NMKLTRAQFEGIVTDLIRRTIAPCQKAMQDAEVSKSDIGEVILVGGMTRMPKVQQTVQDL 402
Query: 358 FGKELSTTLNADEAVTRGCALQCAILSPAFKVREFSITDVVPYPISLRWNSPAEEGSSDC 417
FG+ S +N DEAV G A+Q +L A V + + DV P + + G
Sbjct: 403 FGRAPSKAVNPDEAVAIGAAIQGGVL--AGDVTDVLLLDVTPLSLGIE-----TLGGVFT 455
Query: 418 EVFSKNHAAPFSKVLTFYRKEPFTLEA---YYSSPQDLPYPDPAIAQFSVQKVTPQSDGS 474
++ ++N P K F + +++ + + QF++ + P G
Sbjct: 456 KLINRNTTIPTKKSQVFSTAADGQTQVEIKVCQGEREMAGDNKLLGQFTLIGIPPAPRG- 514
Query: 475 SSKVKVKVRVNVHGIFSVSSASLVEVHKSEENEEPMETDQN---AKEEEKMQVDQEEPHV 531
+++V ++ +GI VS+ K E+ + + +K++ + V E +
Sbjct: 515 VPQIEVTFDIDANGIVHVSAKD-----KGTGREQQIVIQSSGGLSKDDIENMVKNAEKYA 569
Query: 532 EE---QQQQTPAENKAES--EEMETSQAGSKDK 559
EE ++++ A N AE + ET KD+
Sbjct: 570 EEDRRKKERVEAVNMAEGIIHDTETKMEEFKDQ 602
>gi|82880658 heat shock 70kDa protein 14 isoform 1 [Homo sapiens]
Length = 509
Score = 191 bits (485), Expect = 2e-48
Identities = 123/391 (31%), Positives = 200/391 (51%), Gaps = 21/391 (5%)
Query: 1 MSVVGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISNA 60
M+ +G+ LG S VAV + G +AN+ DR TPA +++ +G AAK I N
Sbjct: 1 MAAIGVHLGCTSACVAVYKDGRAGVVANDAGDRVTPAVVAYSENEEIVGLAAKQSRIRNI 60
Query: 61 KNTVQGFKRFHGRAFSDPFVE---AEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQV 117
NTV K+ GR+ SDP + AE L + G ++ EE + E V
Sbjct: 61 SNTVMKVKQILGRSSSDPQAQKYIAESKCLVIE----KNGKLRYEIDTGEETKFVNPEDV 116
Query: 118 TAMLLSKLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAV 177
++ SK+KETA SVL D V++VP + + ++ ++ +A + AG N LRL++E +A
Sbjct: 117 ARLIFSKMKETAHSVLGSDANDVVITVPFDFGEKQKNALGEAARAAGFNVLRLIHEPSAA 176
Query: 178 ALAYGIYKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGRKFD 237
LAYGI QD P + N++ +G ++ +SV N G +VL+T D +GG F
Sbjct: 177 LLAYGI-GQDSPTGKS---NILVFKLGGTSLSLSVMEVNSGIYRVLSTNTDDNIGGAHFT 232
Query: 238 EVLVNHFCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMNDV-- 295
E L + EF + +K D++ RA+++L+ E K +S S CF++ +
Sbjct: 233 ETLAQYLASEFQRSFKHDVRGNARAMMKLTNSAEVAKHSLSTLG-----SANCFLDSLYE 287
Query: 296 --DVSGTMNRGKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEK 353
D ++R +F +C+ L + +R +L+Q +DI V + GG++RIP +++
Sbjct: 288 GQDFDCNVSRARFELLCSPLFNKCIEAIRGLLDQNGFTADDINKVVLCGGSSRIPKLQQL 347
Query: 354 ISKFF-GKELSTTLNADEAVTRGCALQCAIL 383
I F EL ++ DE + G A++ IL
Sbjct: 348 IKDLFPAVELLNSIPPDEVIPIGAAIEAGIL 378
>gi|48928056 heat shock protein 70kDa family member 13 precursor
[Homo sapiens]
Length = 471
Score = 163 bits (412), Expect = 7e-40
Identities = 124/424 (29%), Positives = 204/424 (48%), Gaps = 54/424 (12%)
Query: 3 VVGIDLGFQSCYVAV--ARAGGIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISNA 60
V+GIDLG C V V G ++ I +E P+ +SF + +G + SN
Sbjct: 33 VIGIDLGTTYCSVGVFFPGTGKVKVIPDENGHISIPSMVSFTDNDVYVGYESVELADSNP 92
Query: 61 KNTVQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTAM 120
+NT+ KRF G+ F+ +EAE + ++ G+ VT E + E V +
Sbjct: 93 QNTIYDAKRFIGKIFTAEELEAEIGRYPFKVLN-KNGMVEFSVT-SNETITVSPEYVGSR 150
Query: 121 LLSKLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVALA 180
LL KLKE AE+ L PV + V+SVP + +R S ++A +AGL LR++NE TA A+A
Sbjct: 151 LLLKLKEMAEAYLGMPVANAVISVPAEFDLKQRNSTIEAANLAGLKILRVINEPTAAAMA 210
Query: 181 YGIYKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVL 240
YG++K D+ +V+ +D+G VS+ G A + + LGG+ F++ L
Sbjct: 211 YGLHKADV-------FHVLVIDLGGGTLDVSLLNKQGGMFLTRAMSGNNKLGGQDFNQRL 263
Query: 241 VNHFCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANAS------------------ 282
+ + ++ + Y + S+ + RL Q E +K ++ + S
Sbjct: 264 LQYLYKQIYQTYGF-VPSRKEEIHRLRQAVEMVKLNLTLHQSAQLSVLLTVEEQDRKEPH 322
Query: 283 ----DLPLSIECFMNDVDVSGTMNRG-------------------KFLEMCN-DLLARVE 318
+LP +D V+ RG K + N DL ++
Sbjct: 323 SSDTELPKDKLSSADDHRVNSGFGRGLSDKKSGESQVLFETEISRKLFDTLNEDLFQKIL 382
Query: 319 PPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEKISKFFGKELSTTLNADEAVTRGCAL 378
P++ VL++ L+K +I V +VGG+TRIP +++ I +FFGK+ +T+++ D AV G A+
Sbjct: 383 VPIQQVLKEGHLEKTEIDEVVLVGGSTRIPRIRQVIQEFFGKDPNTSVDPDLAVVTGVAI 442
Query: 379 QCAI 382
Q I
Sbjct: 443 QAGI 446
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 59.7 bits (143), Expect = 1e-08
Identities = 70/292 (23%), Positives = 129/292 (44%), Gaps = 40/292 (13%)
Query: 492 VSSASLVEVHKSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQ-------QQQTPAENKA 544
+SS S + +K EE E EE++ QV +E+ H++E+ +++ AE K
Sbjct: 1529 LSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKR 1588
Query: 545 ESEEMETSQAGSKDKKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKM 604
EE + +Q K + ++ ++ K+ + V + Q DREM + EGK
Sbjct: 1589 AQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKIT-------QDDREM----AQAEGKF 1637
Query: 605 IMQDKLEKERNDAKNAVEEYVYEMRDKLSGEYEKFVSEDDRNSFT-LKLEDTENWLYEDG 663
+++ +R + + E + + R KL+ ++EK E+++ + KL + +N L +
Sbjct: 1638 AQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKV 1697
Query: 664 EDQPKQVYVDKLAELKNLGQPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQY 723
E+ P++ +NL K QE EE EEL S+K +E
Sbjct: 1698 EELPQRE--------QNLDWQEKELAQELEELEWDMEEL------------SWKEEELNQ 1737
Query: 724 DHLDAADMTKVEKSTNEAMEWMNNKLN-LQNKQSLTMDPVVKSKEIEAKIKE 774
+ + K EA+ W KL+ + K + + +++ KE A+ KE
Sbjct: 1738 EEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKE 1789
Score = 47.4 bits (111), Expect = 6e-05
Identities = 33/146 (22%), Positives = 70/146 (47%), Gaps = 3/146 (2%)
Query: 499 EVHKSEENE---EPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAG 555
E H SEE E + +E ++ EE+ + ++EE EE+ ++ E K E E E
Sbjct: 2223 EEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEK 2282
Query: 556 SKDKKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERN 615
+++K + + KK +V+ + +++ + + E L+ E E +++++++E+
Sbjct: 2283 EEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKE 2342
Query: 616 DAKNAVEEYVYEMRDKLSGEYEKFVS 641
K + + E R K E+ +S
Sbjct: 2343 ILKKEKQFKLQEQRRKSLRGRERVLS 2368
Score = 44.3 bits (103), Expect = 5e-04
Identities = 36/154 (23%), Positives = 77/154 (50%), Gaps = 8/154 (5%)
Query: 494 SASLVEVHKSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQ 553
S+ + EV E E ME+ + E+++ +EE EE++++ E + E EE + +
Sbjct: 2214 SSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEE 2273
Query: 554 AGSKDKKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKE 613
G ++K++++ + KK K K + E + +++ E+++ E E + + ++ E+E
Sbjct: 2274 EG-EEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMS---EEETESLSDEEEEEE 2329
Query: 614 RNDAKNAVEEYVYEMRDKLSGEYEKFVSEDDRNS 647
++EE V ++ L E + + E R S
Sbjct: 2330 ----SCSLEEEVDREKEILKKEKQFKLQEQRRKS 2359
Score = 35.4 bits (80), Expect = 0.22
Identities = 59/293 (20%), Positives = 128/293 (43%), Gaps = 29/293 (9%)
Query: 499 EVHKSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKD 558
E K E EE + + EE+ ++ QEE + Q+++ A++K + E E ++
Sbjct: 1745 EKKKLAEEEEALAWQREKLSEEETKLAQEE-ELLIQEKEKLAQHKEKMPEEEERLGRKRE 1803
Query: 559 KKMDQPPQ--AKKAKVKTSTVDLPIENQLLWQ---IDREMLNLYIENEGKMIMQDKL--- 610
+ +++ + K+ + S +L +L+Q + +E NL E E ++ L
Sbjct: 1804 QLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYN 1863
Query: 611 -------EKERNDAKNAV---EEYVYEMRDKLSGEYEKFVSEDDRNSFT-LKLEDTENWL 659
+K+ KN + + + ++ +KL+ E E + + ++ + T KL E+ L
Sbjct: 1864 KERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSL 1923
Query: 660 YEDGEDQPKQVYVDKLAELKNLGQ---PIKIRFQESEERPKLFEELGKQIQQYMKIISSF 716
+ E ++ KLA K + Q ++ ++E L E+ + ++ M+++
Sbjct: 1924 AKKQEKLAQEKM--KLALEKAMVQGKKRLRGELDIAKEEKALNLEMKRLAEEKMRLVEG- 1980
Query: 717 KNKEDQYDHLDAADMTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIE 769
++ + + ++ K T E KL+L+ K L D ++ +E E
Sbjct: 1981 ---KETLSKGETPETSRQRKMTQVEQELFERKLSLEEKILLHEDRILAMEESE 2030
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 59.7 bits (143), Expect = 1e-08
Identities = 52/275 (18%), Positives = 126/275 (45%), Gaps = 16/275 (5%)
Query: 502 KSEENEEPM-ETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKK 560
K +E EE M E + +E+E+ QEE E++++ E+K +E + + K ++
Sbjct: 305 KIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIRE 364
Query: 561 MDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAKNA 620
++ ++ K++ + + + +W+ + ++ + + KM Q+K +E+++
Sbjct: 365 QEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIRE 424
Query: 621 VEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKN 680
EE ++ +K+ E E+ + + + KL + E + E+ E K+ E +
Sbjct: 425 QEEEMWRQEEKIR-ELEEMMQDQEE-----KLREVEEKMQEEEE---------KMQEQEE 469
Query: 681 LGQPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAADMTKVEKSTNE 740
Q + + QE EE+ E+L KQ ++ + +E++ + + EK +
Sbjct: 470 KIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQ 529
Query: 741 AMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKEL 775
+ ++ L ++ + V+ +E+E ++ +L
Sbjct: 530 EEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKL 564
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 59.7 bits (143), Expect = 1e-08
Identities = 52/275 (18%), Positives = 126/275 (45%), Gaps = 16/275 (5%)
Query: 502 KSEENEEPM-ETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKK 560
K +E EE M E + +E+E+ QEE E++++ E+K +E + + K ++
Sbjct: 305 KIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIRE 364
Query: 561 MDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAKNA 620
++ ++ K++ + + + +W+ + ++ + + KM Q+K +E+++
Sbjct: 365 QEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIRE 424
Query: 621 VEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKN 680
EE ++ +K+ E E+ + + + KL + E + E+ E K+ E +
Sbjct: 425 QEEEMWRQEEKIR-ELEEMMQDQEE-----KLREVEEKMQEEEE---------KMQEQEE 469
Query: 681 LGQPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAADMTKVEKSTNE 740
Q + + QE EE+ E+L KQ ++ + +E++ + + EK +
Sbjct: 470 KIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQ 529
Query: 741 AMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKEL 775
+ ++ L ++ + V+ +E+E ++ +L
Sbjct: 530 EEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKL 564
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 59.3 bits (142), Expect = 1e-08
Identities = 47/195 (24%), Positives = 90/195 (46%), Gaps = 9/195 (4%)
Query: 499 EVHKSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKD 558
E K + EE M ++ +E+EK DQEE EE++ + + E EEM Q K
Sbjct: 525 EQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQE-EKM 583
Query: 559 KKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAK 618
++ ++ + ++ K+ + + + +W+ + +M E E KM Q+++ E+ +
Sbjct: 584 QEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQ--EEEDKMQEQEEMMWEQEEKM 641
Query: 619 NAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLAEL 678
EE ++E +K+ + EK +++ K++ E + E E Q + E
Sbjct: 642 QEQEEKMWEQEEKMREQEEKMREQEE------KMQGQEEKMREQEEKMQGQEEKMREQEE 695
Query: 679 KNLGQPIKIRFQESE 693
K GQ K+ QE +
Sbjct: 696 KMRGQEEKMWGQEEK 710
Score = 51.6 bits (122), Expect = 3e-06
Identities = 64/330 (19%), Positives = 147/330 (44%), Gaps = 33/330 (10%)
Query: 502 KSEENEEPM--------ETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQ 553
K E EE M E ++ +E+EK +Q++ +E+Q Q E E EE Q
Sbjct: 270 KMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQ 329
Query: 554 AGSKDKKMDQPPQAKKAKVKTSTVDLPIENQLLWQID----------REMLNLYIENEGK 603
K + ++ ++ +++ + + + +W+ D RE ++ E E K
Sbjct: 330 E-EKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMW-EQEEK 387
Query: 604 MIMQDKLEKERNDAKNAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTEN--WLYE 661
M ++++ +ER EE + E +K+ + E ++++ +L + + W E
Sbjct: 388 MQEEERI-REREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQE 446
Query: 662 DGEDQPKQVY--VDKLAELKNL-GQPIKIRFQES--EERPKLFEELGKQIQQYMKIISSF 716
++Q ++++ +K+ + + + GQ K+ QE E+ +++E+ K Q K+
Sbjct: 447 KMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQE 506
Query: 717 KNKEDQYDHL-DAADMTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKEL 775
+ +Q + L + + + +K + E M + Q ++ T D K +E E +++E
Sbjct: 507 ERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMRE-EERMRER 565
Query: 776 TSTC---SPIISKPKPKVEPPKEEQKNAEQ 802
++ + + K++ +E+ + E+
Sbjct: 566 EKKMREEEEMMREQEEKMQEQEEKMREQEE 595
Score = 48.9 bits (115), Expect = 2e-05
Identities = 65/327 (19%), Positives = 145/327 (44%), Gaps = 24/327 (7%)
Query: 504 EENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKKMDQ 563
E++E E ++ +E+EKM +E+ EE+ ++ + + E E M + + ++ +
Sbjct: 363 EQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENM 422
Query: 564 PPQAKKAKVKTSTVDLPIENQLLWQIDR--EMLNLYIENEGKMIMQDKL---EKE--RND 616
Q +K + LP + + LW+ ++ E E E K+ Q+++ EK+ R +
Sbjct: 423 WEQEEK---EWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQE 479
Query: 617 AKNAVEEYVYEMRDKLSGEYEKFVSEDDRN-SFTLKLEDTENWLYE-----DGEDQPKQV 670
E+ ++E +K+ + +K +++R +L + E + E E++ ++
Sbjct: 480 KMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREE 539
Query: 671 YVDKLAELKNLGQPIKI----RFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHL 726
+ E K Q K+ R +E E++ + EE+ ++ ++ M+ ++++
Sbjct: 540 KKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWE 599
Query: 727 DAADMTKVEKSTNEAMEWM---NNKLNLQNKQSLTMDPVVKSKEIEAKIKELTSTCSPII 783
M + E+ E E M + +Q ++ + + K +E E K+ E
Sbjct: 600 QEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQE 659
Query: 784 SKPKPKVEPPK-EEQKNAEQNGPVDGQ 809
K + + E + +E+K EQ + GQ
Sbjct: 660 EKMREQEEKMQGQEEKMREQEEKMQGQ 686
Score = 44.3 bits (103), Expect = 5e-04
Identities = 61/325 (18%), Positives = 139/325 (42%), Gaps = 22/325 (6%)
Query: 497 LVEVHKSEENEEPMETDQNAKEEEKMQVDQEEP--HVEEQQQQTPAENKAESEEMETSQA 554
L +V + EE ++ +E+EK QEE EE+ ++ + + + E+M +
Sbjct: 224 LPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEK 283
Query: 555 GSKDKKMDQPPQAK----KAKVKTSTVDLPIENQLLWQID---REMLNLYIENEGKMIMQ 607
++++ + Q K + K++ + + + +W+ + RE E ++ Q
Sbjct: 284 RLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQ 343
Query: 608 DKLEKERNDAKNAVEEYVYEMRDKL------SGEYEKFVSEDDRNSFTLKLEDTENWLYE 661
+K +E+ EE ++E ++L E EK ++++ ++ + E + E
Sbjct: 344 EKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMRE 403
Query: 662 DGEDQPKQVYVDKLAELKNLGQPIKIRFQES---EERPKLFEELGKQIQQYMKIISSFKN 718
+ E +Q + E +N+ + + +Q+ E++ KL+E+ K +Q KI +
Sbjct: 404 EEETMREQEEKMQKQE-ENMWEQEEKEWQQQRLPEQKEKLWEQ-EKMQEQEEKIWEQEEK 461
Query: 719 KEDQYDHL-DAADMTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKELTS 777
DQ + M + EK + + + +++++ D + E + +++E
Sbjct: 462 IRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEE 521
Query: 778 TCSPIISKPKPKVEPPKEEQKNAEQ 802
K + E +EE+K EQ
Sbjct: 522 RMRE-QKKMWQQEEKMREEKKTQEQ 545
Score = 43.5 bits (101), Expect = 8e-04
Identities = 27/132 (20%), Positives = 65/132 (49%), Gaps = 1/132 (0%)
Query: 502 KSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKKM 561
+ EE ++ E ++ E+E+ +QEE E++++ E K +E + K ++
Sbjct: 620 EQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQ 679
Query: 562 DQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAKNAV 621
++ Q ++ K++ + + + +W + +M + G+ M++K E+ R D K +
Sbjct: 680 EEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIR-DQKEKM 738
Query: 622 EEYVYEMRDKLS 633
+E + E ++ S
Sbjct: 739 QERLPEHEERCS 750
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 58.2 bits (139), Expect = 3e-08
Identities = 60/290 (20%), Positives = 131/290 (45%), Gaps = 20/290 (6%)
Query: 499 EVHKSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKD 558
E K E E M ++ +E+EK DQEE ++E+++ E K EE + K
Sbjct: 415 EQEKMWEQVEKMREEKKMQEQEKKTRDQEE-KMQEEERIREREKKMREEEETMREQEEKM 473
Query: 559 KKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDR--EMLNLYIENEGKMIMQDKL---EKE 613
+K ++ ++ K + LP + + LW+ ++ E E E K+ Q+++ EK+
Sbjct: 474 QKQEENMWEQEEK-EWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKK 532
Query: 614 --RNDAKNAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYED--GEDQPKQ 669
R + E+ ++E +K+ + +K +++R + ++ + W E+ E++ +
Sbjct: 533 MWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMR 592
Query: 670 VYVDKLAELKNLGQPIKIRFQESEER-----PKLFEELGKQIQQYMKIISSFKNKEDQYD 724
K+ E + + + + + QE EE+ K++E+ K +Q K+ + +Q +
Sbjct: 593 EREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEE 652
Query: 725 HLDAADMTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKE 774
+ +K W + K+ Q K + + + +++E K +E
Sbjct: 653 KMWEQQRLPEQKE----KLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQE 698
Score = 52.0 bits (123), Expect = 2e-06
Identities = 55/235 (23%), Positives = 106/235 (45%), Gaps = 25/235 (10%)
Query: 502 KSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKKM 561
K E E E ++ +EEE+M +QEE E++++ E K +E + + K +
Sbjct: 584 KMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQ 643
Query: 562 DQPPQAKKAKVKTSTVDLPIENQLLWQIDR-EMLNLYIENEGKMIMQDKLEKERN----- 615
++ ++ K+ LP + + LW+ ++ + E E K+ Q+K+EK+
Sbjct: 644 EEKMWEQEEKM-WEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKK 702
Query: 616 --DAKNAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVD 673
D + EE R+K E E+ + E + K+++ E + E E+ +Q
Sbjct: 703 TWDQEKMREEESMREREKKMREEEEMMREQEE-----KMQEQEEKMQEQEEEMWEQ---- 753
Query: 674 KLAELKNLGQPIKIRFQE--SEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHL 726
E K Q K+ Q+ E++ KL+E +++Q+ KI + DQ + +
Sbjct: 754 ---EEKMWEQEEKMWEQQRLPEQKEKLWEH--EKMQEQEKIWEQEEKMRDQEEKM 803
Score = 48.9 bits (115), Expect = 2e-05
Identities = 51/223 (22%), Positives = 98/223 (43%), Gaps = 28/223 (12%)
Query: 497 LVEVHKSEENEEPMETDQNAKEEEKMQV----------DQEEPHVEEQQQQTPAENKAES 546
L E K +E E+ E ++ E+EKM+ DQE+ EE ++ + + E
Sbjct: 667 LWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEE 726
Query: 547 E---EMETSQAGSKDKKMDQPPQAKKAKVKTSTVD--------LPIENQLLWQIDREMLN 595
E E E ++K +Q + + + K + LP + + LW+ ++
Sbjct: 727 EMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQ 786
Query: 596 LYI-ENEGKMIMQDKLEKERNDAKNAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLED 654
I E E KM Q++ + + + EE + +K+ G+ EK ++++ + ++
Sbjct: 787 EKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEK----MWGQE 842
Query: 655 TENWLYEDGEDQPKQVYVDKLAEL--KNLGQPIKIRFQESEER 695
+ W E+ ++ Q +K+ E K GQ K+R QE + R
Sbjct: 843 EKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMR 885
Score = 47.4 bits (111), Expect = 6e-05
Identities = 54/300 (18%), Positives = 137/300 (45%), Gaps = 16/300 (5%)
Query: 505 ENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKKMDQP 564
E +E E ++ +E+E+ +QEE E++++ E + +E + + K + ++
Sbjct: 339 EQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEER 398
Query: 565 PQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAKNAVEEY 624
+ +++ + + ++ Q+++ + E KM Q+K +++ + K EE
Sbjct: 399 MWEQDERLREKEERMREQEKMWEQVEK------MREEKKMQEQEKKTRDQEE-KMQEEER 451
Query: 625 VYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQV--YVDKLAELKNLG 682
+ E K+ E E ++++ ++ ++ W E+ E Q +++ +KL E + +
Sbjct: 452 IREREKKMREEEETMREQEEK----MQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKM- 506
Query: 683 QPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAADMTKVEKSTNEAM 742
Q + + E EE+ + EE+ Q ++ M + +EDQ + M E+ +
Sbjct: 507 QEQEEKIWEQEEKIRDQEEMWGQ-EKKMWRQEKMREQEDQMWEQE-EKMRDQEQKMWDQE 564
Query: 743 EWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKELTSTCSPIISKPKPKVEPPKEEQKNAEQ 802
E M K Q K++ + ++ +E + ++ ++ + + K++ +E+ + E+
Sbjct: 565 ERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEE 624
Score = 47.4 bits (111), Expect = 6e-05
Identities = 52/284 (18%), Positives = 128/284 (45%), Gaps = 17/284 (5%)
Query: 499 EVHKSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKD 558
E E+ E+ E ++ +E+E+ QEE E+++Q E K +E + +D
Sbjct: 347 EEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQE---ERMWEQD 403
Query: 559 KKMDQPPQAKKAKVKT-STVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDA 617
+++ + + + + K V+ E + + + +++ + E KM ++++ +ER
Sbjct: 404 ERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTR----DQEEKMQEEERI-REREKK 458
Query: 618 KNAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTEN--WLYEDGEDQPKQVY--VD 673
EE + E +K+ + E ++++ +L + + W E ++Q ++++ +
Sbjct: 459 MREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEE 518
Query: 674 KLAELKNL-GQPIKIRFQES--EERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAAD 730
K+ + + + GQ K+ QE E+ +++E+ K Q K+ + E + +
Sbjct: 519 KIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKT 578
Query: 731 MTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKE 774
+ EK E + ++ ++ + + K +E E K++E
Sbjct: 579 WDQEEKMREEE-RMREREKKMREEEEMMREQEEKMQEQEEKMQE 621
Score = 42.0 bits (97), Expect = 0.002
Identities = 60/319 (18%), Positives = 141/319 (44%), Gaps = 41/319 (12%)
Query: 464 VQKVTPQSDGSSSKVKVKVRVNVHGIFSVSSASLVEVHKSEENEEPMETDQNAKEEEKMQ 523
+Q+ P ++ S++++ V+ + + L +V + EE ++ +E+EK
Sbjct: 230 LQEKLPLAESEKSEIQLNVK-ELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKI 288
Query: 524 VDQEEP--HVEEQQQQTPAENKAESEEMETSQAGSKDKKMDQPPQAKKAK----VKTSTV 577
QEE EE+ ++ + + + E+M + ++++ + Q K+ + ++
Sbjct: 289 RKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEE 348
Query: 578 DLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAKNAVEEYVYEMRDKLSGEYE 637
+ + + +W+ + +M E E KM Q++ E+ E+ + E K+ + E
Sbjct: 349 QMQEQEEKMWEQEEKMR----EQEEKMWRQEERLWEQ-------EKQMREQEQKMRDQEE 397
Query: 638 KFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKNLGQPIKIRFQESEERPK 697
+ +D+R L + E + E + V+K+ E K + + K + ++ EE+ +
Sbjct: 398 RMWEQDER------LREKEERM---REQEKMWEQVEKMREEKKMQEQEK-KTRDQEEKMQ 447
Query: 698 LFEELGKQIQQYMKIISSFKNKEDQYDHLDAADMTKVEKS--TNEAMEWMNNKLNLQNKQ 755
E + ++ ++ + + + +E++ M K E++ E EW +L Q ++
Sbjct: 448 EEERIREREKKMREEEETMREQEEK--------MQKQEENMWEQEEKEWQQQRLPEQKEK 499
Query: 756 SLTMDPVVKSKEIEAKIKE 774
+ K +E E KI E
Sbjct: 500 LWEQE---KMQEQEEKIWE 515
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 55.5 bits (132), Expect = 2e-07
Identities = 54/295 (18%), Positives = 128/295 (43%), Gaps = 16/295 (5%)
Query: 491 SVSSASLVEVHKSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEME 550
+++ ASL + +N+ ++ ++EEK + QE +EE + T + K + + E
Sbjct: 124 TITDASLSLPSRRMQNDTA--ENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAE 181
Query: 551 TSQAGSKDKKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKL 610
++ K+K+ ++ + K+ + + V++ +E + + E + + ++N + K
Sbjct: 182 ENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTT-ESQEETVVMSLKNGQISSEEPKQ 240
Query: 611 EKERNDAKNAVEEY-VYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQ 669
E+ER + + + E DK E E+ E + +K E + E + ++
Sbjct: 241 EEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERE-RIKAEQDKKIADERARIEAEE 299
Query: 670 VYVDKLAELKNLGQPIKIRFQE---SEERPKLFEELGKQIQQYMKIISSFKN-------- 718
+ E + + ++R +E +EER ++ EE + ++ +I K
Sbjct: 300 KAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRI 359
Query: 719 KEDQYDHLDAADMTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIK 773
KE++ + + E+ +E L+ K+ + +K +++E KI+
Sbjct: 360 KEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIE 414
Score = 32.7 bits (73), Expect = 1.4
Identities = 56/317 (17%), Positives = 121/317 (38%), Gaps = 70/317 (22%)
Query: 502 KSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKKM 561
+ ++ + +E ++A +E K++ ++ E +E + E KA+ ++++T+ + ++
Sbjct: 384 EEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVN---EKKAQEDKLQTAVLKKQGEEK 440
Query: 562 DQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAKNAV 621
QAK+ K++ E I +K++K++
Sbjct: 441 GTKVQAKREKLQEDKPTFKKEE---------------------IKDEKIKKDKEP----- 474
Query: 622 EEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKNL 681
+E V D+ G E V + T KL+ TEN
Sbjct: 475 KEEVKSFMDRKKGFTE--VKSQNGEFMTHKLKHTEN-------------------TFSRP 513
Query: 682 GQPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAADMTKVEKSTNEA 741
G + +E+E P++ E GK++++ + + ++ + K+++ EA
Sbjct: 514 GGRASVDTKEAEGAPQV--EAGKRLEELRR----------RRGETESEEFEKLKQKQQEA 561
Query: 742 ---MEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKELTSTCSPIISKPKPKVEPPKEEQK 798
+E + K + K + K +E + K++E + K ++E + E
Sbjct: 562 ALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEK-----RRLKEEIERRRAEAA 616
Query: 799 NAEQNGPVDGQGDNPGP 815
Q P DG D+ P
Sbjct: 617 EKRQKMPEDGLSDDKKP 633
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 55.1 bits (131), Expect = 3e-07
Identities = 47/236 (19%), Positives = 111/236 (47%), Gaps = 27/236 (11%)
Query: 499 EVHKSEENEEPMETDQNAKEEEKMQVDQEEPHVEE-----QQQQTPAENKAESEEMETSQ 553
E K +E EE ++ +E+E++ +E+ H +E +++ E K +E + +
Sbjct: 454 EEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIRE 513
Query: 554 AGSKDKKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKE 613
K + ++ + ++ K++ + + +++ + + +M E E KM Q+K+ ++
Sbjct: 514 QEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKM----GEQEEKMQEQEKMRRQ 569
Query: 614 RNDAKNAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVD 673
+ EE + E ++K+ + EK +++ K+ + E + E E +Q +
Sbjct: 570 EEKIREQ-EEKIREQKEKIREQEEKIWEQEE------KIREQEEMMQEQEEKMWEQ--EE 620
Query: 674 KLAELKNLGQPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAA 729
K+ E + + QE EE+ + EE K +Q +++ + ++ +HL+AA
Sbjct: 621 KMCEQEE-------KMQEQEEKMRRQEE--KMWEQEVRLRQQEEKMQEHQEHLEAA 667
Score = 52.8 bits (125), Expect = 1e-06
Identities = 63/287 (21%), Positives = 130/287 (45%), Gaps = 26/287 (9%)
Query: 502 KSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKKM 561
K E E+ E ++ +EEEK++ +QE+ +E + E E EE Q +KKM
Sbjct: 385 KMHEQEKIREQEEKRQEEEKIR-EQEKRQEQEAKMWRQEEKIREQEEKIREQ----EKKM 439
Query: 562 DQPPQAKKAKVKTSTVDLPIENQLLWQID---REMLNLYIENEGKMIMQDKLEKE----- 613
+ + + K + E + +W+ + RE ++ + E KM Q+K+ K+
Sbjct: 440 WRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKE-KMHEQEKIRKQEEKVW 498
Query: 614 -RNDAKNAVEEYVYEMRDKLSGEYEKFVSEDDR-NSFTLKLEDTENWLYEDGEDQPKQVY 671
+ + + EE + E +K+ + EK ++++ K+ + E + E E +Q
Sbjct: 499 RQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQ-- 556
Query: 672 VDKLAELKNL-GQPIKIRFQES---EERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLD 727
+K+ E + + Q KIR QE E++ K+ E+ K +Q KI + +E+ +
Sbjct: 557 EEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKI----REQEEMMQEQE 612
Query: 728 AADMTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKE 774
+ EK + + + ++ ++ + V+ ++ E K++E
Sbjct: 613 EKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 659
Score = 51.2 bits (121), Expect = 4e-06
Identities = 66/345 (19%), Positives = 142/345 (41%), Gaps = 32/345 (9%)
Query: 504 EENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKKMDQ 563
E E+ E ++ +E+E+ +QEE +++ E K +E + K +++++
Sbjct: 311 EWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEE 370
Query: 564 PPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYI-------ENEGKMIMQDKLEKERND 616
K+ K++ + + ++ Q ++ I E E KM Q++ +E+ +
Sbjct: 371 MMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEE 430
Query: 617 AKNAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLA 676
E+ ++ +K+ E EK E+ R E E W E+ + ++++ K
Sbjct: 431 KIREQEKKMWRQEEKIH-EQEKIREEEKRQ------EQEEMWRQEEKIREQEEIWRQK-- 481
Query: 677 ELKNLGQPIKIRFQESE---ERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAADMTK 733
+ + + KIR QE + + K+ ++ K +Q K+ + +Q + + +
Sbjct: 482 --EKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKI-----RE 534
Query: 734 VEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKELTSTCSPIISKPKPKVEPP 793
E+ E E M + +Q M K + E KI+E I + K K+
Sbjct: 535 QEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEK----IREQKEKIR-- 588
Query: 794 KEEQKNAEQNGPVDGQGDNPGPQAAEQGTDTAVPSDSDKKLPEMD 838
++E+K EQ + Q + Q + + ++K+ E +
Sbjct: 589 EQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQE 633
Score = 45.1 bits (105), Expect = 3e-04
Identities = 52/242 (21%), Positives = 102/242 (42%), Gaps = 28/242 (11%)
Query: 499 EVHKSEENEEPMETDQNAKEEEKMQ------VDQEEPHVEEQQQQTPAENK--------- 543
E K E EE + ++ +E+EK Q QEE E++++ E K
Sbjct: 388 EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIH 447
Query: 544 ------AESEEMETSQAGSKDKKMDQPPQAKKAKVKTSTVD-LPIENQLLWQIDREMLN- 595
E + E + +++K+ + + + K K + + + + +W+ + +M +
Sbjct: 448 EQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQ 507
Query: 596 --LYIENEGKMIMQDKLEKERNDAKNAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLE 653
E E KM Q++ +E+ + EE + E + + + EK ++++ K+
Sbjct: 508 EEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMR 567
Query: 654 DTENWLYEDGEDQPKQVYVDKLAELKNLGQPIKIRFQE---SEERPKLFEELGKQIQQYM 710
E + E E +Q + E K Q KIR QE E+ K++E+ K +Q
Sbjct: 568 RQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEE 627
Query: 711 KI 712
K+
Sbjct: 628 KM 629
Score = 44.7 bits (104), Expect = 4e-04
Identities = 65/348 (18%), Positives = 155/348 (44%), Gaps = 35/348 (10%)
Query: 503 SEENEEPM--ETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKK 560
+++ EE M + ++ + EEK+Q +QEE E++++ E K +E + K ++
Sbjct: 295 NQQQEEKMWRQEEKIQEWEEKIQ-EQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRR 353
Query: 561 MDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKL----EKERND 616
++ K+ K++ +++W+ + ++ L E KM Q+K+ EK + +
Sbjct: 354 QEEMMWEKEEKMRRL-------EEMMWEKEEKIREL----EEKMHEQEKIREQEEKRQEE 402
Query: 617 AKNAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDG-EDQPKQVYVDKL 675
K +E E K+ + EK ++++ ++ ++ + W E+ +Q K +K
Sbjct: 403 EKIREQEKRQEQEAKMWRQEEKIREQEEK----IREQEKKMWRQEEKIHEQEKIREEEKR 458
Query: 676 AELKNL-GQPIKIRFQE----SEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAAD 730
E + + Q KIR QE +E+ E++ KQ ++ + ++E++ +
Sbjct: 459 QEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKM 518
Query: 731 MTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKELTSTCSPIISKPKPKV 790
+ EK + + + ++ ++ + + K E E K++E + + + K+
Sbjct: 519 WRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEK-----MRRQEEKI 573
Query: 791 EPPKEEQKNAEQNGPVDGQGDNPGPQAAEQGTDTAVPSDSDKKLPEMD 838
++E+K EQ + Q + Q + + + ++K+ E +
Sbjct: 574 R--EQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQE 619
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 54.3 bits (129), Expect = 5e-07
Identities = 42/197 (21%), Positives = 91/197 (46%), Gaps = 6/197 (3%)
Query: 499 EVHKSEENEEPM-ETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSK 557
E K +E E M ++ +E+E+ +QEE E++++ E K +E E + K
Sbjct: 374 EQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEK 433
Query: 558 DKKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDA 617
++ ++ + ++ K++ + + +++ + + +M E EGKM Q+ +E+ +
Sbjct: 434 MRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKM----GEQEGKMCEQEAKMQEQEEK 489
Query: 618 KNAVEEYVYEMRDKLSGEYEKFVSEDD-RNSFTLKLEDTENWLYEDGEDQPKQVYVDKLA 676
EE + E K+ + EK +++ K+ + E + E E +Q +
Sbjct: 490 MRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQ 549
Query: 677 ELKNLGQPIKIRFQESE 693
E K Q +++R QE +
Sbjct: 550 EEKMREQEVRLRQQEEK 566
Score = 49.3 bits (116), Expect = 1e-05
Identities = 48/276 (17%), Positives = 122/276 (44%), Gaps = 26/276 (9%)
Query: 502 KSEENEEPM-ETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKK 560
K EE M E ++ + +E+M ++EE E +++ E E EE + ++++
Sbjct: 317 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQE 376
Query: 561 MDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAKNA 620
Q +AK +W+ + ++ E E K+ Q+++ +E+ +
Sbjct: 377 KRQEQEAK-----------------MWRQEEKIR----EQEEKIREQEEMMQEQEEKMGE 415
Query: 621 VEEYVYEMRDKLSGEYEKFVSEDDR-NSFTLKLEDTENWLYEDGEDQPKQVYVDKLAELK 679
EE ++E +++ + EK ++++ K+ + E + E +++ Q +K+ E +
Sbjct: 416 QEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIRE--QEEMMQEQEEKMGEQE 473
Query: 680 NLGQPIKIRFQESEERPKLFEE-LGKQIQQYMKIISSFKNKEDQYDHLDAADMTKVEKST 738
+ + QE EE+ + EE + +Q ++ + + +E+ + + EK
Sbjct: 474 GKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMC 533
Query: 739 NEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKE 774
+ + + ++ ++ + V+ ++ E K++E
Sbjct: 534 EQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQE 569
Score = 47.4 bits (111), Expect = 6e-05
Identities = 59/274 (21%), Positives = 116/274 (42%), Gaps = 29/274 (10%)
Query: 505 ENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKKMDQP 564
+ E+ E ++ +E+E+ +QEE +++ E K +E + K +++++
Sbjct: 293 QEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEE- 351
Query: 565 PQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAKNAVEEY 624
++ K++ E ++ Q R+ E E KM Q++ +E+ + EE
Sbjct: 352 KMHEQEKIREQEEKRQEEEKIREQEKRQ------EQEAKMWRQEEKIREQEEKIREQEEM 405
Query: 625 VYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKNLGQP 684
+ E +K+ GE E+ K+ + E + E E +Q + E K Q
Sbjct: 406 MQEQEEKM-GEQEE------------KMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQE 452
Query: 685 IKIRFQE---SEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAADMTKVEKSTNEA 741
KIR QE E+ K+ E+ GK +Q K+ ++++ + + EK E
Sbjct: 453 EKIREQEEMMQEQEEKMGEQEGKMCEQEAKM-----QEQEEKMRRQEEKIREQEKKIREQ 507
Query: 742 MEWMNNKLNLQNKQSLTM-DPVVKSKEIEAKIKE 774
E + + + +Q M + K E E K++E
Sbjct: 508 EEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE 541
>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
[Homo sapiens]
Length = 2073
Score = 53.1 bits (126), Expect = 1e-06
Identities = 92/405 (22%), Positives = 161/405 (39%), Gaps = 60/405 (14%)
Query: 436 RKEPFTLEAYYSSPQDLPYPDPAIAQFSVQKVTPQSDGSSSKVKVKVRVNVHGIFSVSSA 495
RK F L Y +P + P QK T + S S ++++ V G +
Sbjct: 1265 RKTGFKLNLY--TPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLPQ- 1321
Query: 496 SLVEVHKSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAG 555
E ++ EE P+ + + E+ + + + E EE++++ E + E EE E G
Sbjct: 1322 ---EENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEE--GGG 1376
Query: 556 SKDKKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERN 615
+ +K D +K + + ST + D L+ + E E ++ E N
Sbjct: 1377 NVEKDPDGAKSQEKEEPEISTE----------KEDSARLDDHEEEE-----EEDEEPSHN 1421
Query: 616 DAKNAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWL---YEDGEDQPKQVY- 671
+ +A +E M S E EK E R SF LE+ E +L + G P+ +
Sbjct: 1422 EDHDADDEDDSHME---SAEVEK--EELPRESFKEVLENQETFLDLNVQPGHSNPEVLMD 1476
Query: 672 --VDKLA----ELKNL-GQPIKIRFQESEERPKLFEELGKQIQQYMK-IISSFKNKEDQY 723
VD A E K L G P + ES+E P E+ KQ Q+ K + + FK
Sbjct: 1477 CGVDLTASCNSEPKELAGDPEAV--PESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPAT 1534
Query: 724 DHLDAADMTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKELTSTCSPII 783
+D+ + V+ T E+ E Q T +++E ++ T
Sbjct: 1535 MEIDSETVQAVQSLTQESSE-----------QDDTFQDCAETQEACRSLQNYTR------ 1577
Query: 784 SKPKPKVEPPKEEQKNAEQNGPVDGQGDNPGPQAAEQGTDTAVPS 828
+ P++ ++ + ++ + PV +PG Q+ +VP+
Sbjct: 1578 ADQSPQIATTLDDCQQSDHSSPVSSVHSHPG-QSVRSVNSPSVPA 1621
Score = 37.7 bits (86), Expect = 0.045
Identities = 17/60 (28%), Positives = 32/60 (53%)
Query: 505 ENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKKMDQP 564
E + +E + + EEE+ + D+EE EE++++ E + E EE E S ++ +P
Sbjct: 1057 ERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKP 1116
Score = 36.6 bits (83), Expect = 0.100
Identities = 21/89 (23%), Positives = 41/89 (46%)
Query: 489 IFSVSSASLVEVHKSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEE 548
+ +S S E + E+ EE E ++ ++EE+ + ++EE E Q P K +S
Sbjct: 1061 LLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVA 1120
Query: 549 METSQAGSKDKKMDQPPQAKKAKVKTSTV 577
++ + KK + + + V T T+
Sbjct: 1121 IKRKRPFVLKKKRGRKRRRINSSVTTETI 1149
Score = 32.0 bits (71), Expect = 2.5
Identities = 70/360 (19%), Positives = 129/360 (35%), Gaps = 70/360 (19%)
Query: 500 VHKSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDK 559
+H E E Q + ++ ++EE EE++++ E + E EE E + ++
Sbjct: 1046 LHSPESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEN 1105
Query: 560 KMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAKN 619
PP+ K + ++ I+ + +++ K ++R +
Sbjct: 1106 IQSSPPRLTKPQ-----------------------SVAIKRKRPFVLKKKRGRKRRRINS 1142
Query: 620 AV-EEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLAEL 678
+V E + E + L+ E F + D+ E + EDG ++ + K +
Sbjct: 1143 SVTTETISETTEVLN---EPFDNSDEERPMPQLEPTCEIEVEEDG----RKPVLRKAFQ- 1194
Query: 679 KNLGQPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAADMTKVE--- 735
QP K R E EE GK + N D +L E
Sbjct: 1195 ---HQPGKKRQTEEEE--------GKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLK 1243
Query: 736 ------KSTNEAM-EWMNN-------KLNLQNKQSLTMDPVVK-SKEIEAKIKELTSTCS 780
K T + +W N KLNL M+P + + E + + E ++ S
Sbjct: 1244 CKQVWPKGTKRGLSKWRQNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPS 1303
Query: 781 PIISKPKPKVEP----PKEEQKNAEQNGPVDGQGDNPGPQAAEQGTDTAVPSDSDKKLPE 836
PI + + K P+EE + E PV +P E+ D + + +++ E
Sbjct: 1304 PIRIEEEVKETGEALLPQEENRREETCAPV-----SPNTSPGEKPEDDLIKPEEEEEEEE 1358
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 52.4 bits (124), Expect = 2e-06
Identities = 55/245 (22%), Positives = 107/245 (43%), Gaps = 22/245 (8%)
Query: 499 EVHKSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKD 558
++ K EE E +Q K+EE+M +E+ +E+Q Q E + EE Q ++
Sbjct: 214 QMQKQEEQMGEQE-EQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQ---EE 269
Query: 559 KKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAK 618
+ +Q Q K K +T + E + + E + E E +M Q++ +E+ +
Sbjct: 270 QMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMR---EQEEQMREQEEQMREQEEQM 326
Query: 619 NAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLAEL 678
EE ++E ++++ + E+ ++++ + E E KQ + E
Sbjct: 327 GKQEEQMWEQKEQMWEQKEQMWKQEEQ-------------MGEQEEQMQKQEEQVRKQEE 373
Query: 679 KNLGQPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAADMTKVEKST 738
+ Q ++R QE + R K E++G+Q +Q + + +E+Q M K E+
Sbjct: 374 QMRKQEEQMRKQEEQMR-KQEEQMGEQKEQMGEQKEQMREQEEQMGE-QKEQMRKQEEHM 431
Query: 739 NEAME 743
E E
Sbjct: 432 GEQKE 436
Score = 42.4 bits (98), Expect = 0.002
Identities = 41/258 (15%), Positives = 112/258 (43%), Gaps = 11/258 (4%)
Query: 504 EENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKKMDQ 563
E+ + E + +E+E +QE E+++Q E + + +E + + + +K ++
Sbjct: 175 EQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEE 234
Query: 564 PPQAKKAKVKTSTVDLPIENQLLWQIDREMLNL--YIENEGKMIMQDKLEKERNDAKNAV 621
++ +V+ + + + + + + +M + + + +++ K + E+ +
Sbjct: 235 QMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQ 294
Query: 622 EEYVYEMRDKLSGEYEKF-VSEDDRNSFTLKLEDTENWLYEDGE---DQPKQVYVDKLAE 677
EE + E +++ + E+ E+ ++ E ++E E +Q +Q++ +
Sbjct: 295 EEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQE--- 351
Query: 678 LKNLGQPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAADMTKVEKS 737
+ +G+ + ++ E+ K E++ KQ +Q K + +E+Q M + ++
Sbjct: 352 -EQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGE-QKEQMGEQKEQ 409
Query: 738 TNEAMEWMNNKLNLQNKQ 755
E E M + KQ
Sbjct: 410 MREQEEQMGEQKEQMRKQ 427
Score = 39.3 bits (90), Expect = 0.015
Identities = 70/325 (21%), Positives = 132/325 (40%), Gaps = 26/325 (8%)
Query: 497 LVEVHKSE------ENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEME 550
LVE KSE E + +ETD+ +E QV ++E V EQ+ Q E + + E E
Sbjct: 22 LVETEKSEIQLHIKELKRKLETDKIPLPQEG-QVREQEGQVREQEGQV-REQEGQVREQE 79
Query: 551 TSQAGSKDKKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKL 610
+ + +Q Q ++ + + + + Q Q+ RE E EG++ Q+
Sbjct: 80 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQ-EGQV-REQEGQVREQEGQVREQEGQ 137
Query: 611 EKERNDAKNAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQV 670
+E+ E V E ++ E E V E + ++ + E + E E Q ++
Sbjct: 138 VREQEGQVREQEGQVREQEGQVR-EQEGQVREQEG-----QVREQEGQVREQ-EGQVREQ 190
Query: 671 YVDKLAELKNLGQPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLD--- 727
+ +G+ + ++ E+ K E++G+Q +Q K +E+Q +
Sbjct: 191 EGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQV 250
Query: 728 ---AADMTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKELTSTCSPIIS 784
M K E+ E E M + KQ + ++ E E +++E
Sbjct: 251 QKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEE 310
Query: 785 KPKPKVEPPKEEQKNAEQNGPVDGQ 809
+ + + E +E++ EQ G + Q
Sbjct: 311 QMREQEEQMREQE---EQMGKQEEQ 332
Score = 36.6 bits (83), Expect = 0.100
Identities = 27/149 (18%), Positives = 71/149 (47%), Gaps = 11/149 (7%)
Query: 497 LVEVHKSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGS 556
L + ++E+ E+ E ++ +E+E+ +QEE E+++Q E + +E + +
Sbjct: 279 LKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWE--Q 336
Query: 557 KDKKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERND 616
K++ +Q Q K + + E + Q E + + E +M Q++ +++ +
Sbjct: 337 KEQMWEQKEQMWKQEEQMG------EQEEQMQKQEEQVR---KQEEQMRKQEEQMRKQEE 387
Query: 617 AKNAVEEYVYEMRDKLSGEYEKFVSEDDR 645
EE + E ++++ + E+ ++++
Sbjct: 388 QMRKQEEQMGEQKEQMGEQKEQMREQEEQ 416
>gi|239752551 PREDICTED: hypothetical protein [Homo sapiens]
Length = 238
Score = 52.0 bits (123), Expect = 2e-06
Identities = 50/218 (22%), Positives = 97/218 (44%), Gaps = 11/218 (5%)
Query: 505 ENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKKMDQP 564
E E E ++ +EEE+M +QEE E++++ E K +E + + K + ++
Sbjct: 3 EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 62
Query: 565 PQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAKNAVEEY 624
++ K+ LP + + +W+ D E L E + M ++EK R + K EE
Sbjct: 63 MWEQEEKM-WEQQRLPEQKEKMWEQD-ERLREKEERMREQKMWQQVEKMR-EKKKTQEEK 119
Query: 625 VYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKNLGQP 684
+ E +K+ + E +++ K+++ E ++E E +Q + E K GQ
Sbjct: 120 MQEQEEKMQEQEEMMWEQEE------KMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQE 173
Query: 685 IKIRFQE--SEERPKLFEELGKQIQQYMKIISSFKNKE 720
K+R E E + + Q+ M++ KN +
Sbjct: 174 EKMRDVEPAGGEAGEGSPQDNPTAQEIMQLFCGMKNAQ 211
Score = 46.6 bits (109), Expect = 1e-04
Identities = 45/184 (24%), Positives = 78/184 (42%), Gaps = 14/184 (7%)
Query: 499 EVHKSEENEEPMETDQNAK---EEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAG 555
E K EE M +Q K +EEKM+ +E+ +E++ Q E E EE Q
Sbjct: 9 EREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEE 68
Query: 556 SKDKKMDQPPQAKKAKVKTSTV---DLPIENQLLWQIDREML-------NLYIENEGKMI 605
++ P Q +K + + + + Q +WQ +M E E KM
Sbjct: 69 KMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEKMQ 128
Query: 606 MQDKLEKERNDAKNAVEEYVYEMRDKLSGEYEKFVSEDDR-NSFTLKLEDTENWLYEDGE 664
Q+++ E+ + EE ++E +K+ + EK ++++ K+ D E E GE
Sbjct: 129 EQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVEPAGGEAGE 188
Query: 665 DQPK 668
P+
Sbjct: 189 GSPQ 192
Score = 45.8 bits (107), Expect = 2e-04
Identities = 41/193 (21%), Positives = 93/193 (48%), Gaps = 16/193 (8%)
Query: 517 KEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKKMDQPPQAKKAKVKTST 576
+EEE+M+ ++E+ EE++ E K + +E + + K + ++ Q ++ K+
Sbjct: 2 REEERMR-EREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 60
Query: 577 VDLPIENQLLWQIDREMLNLYIENEGKMIMQDK--LEKERNDAKNAVEEYVYEMRDKLSG 634
+ + + +W+ R E + KM QD+ EKE + + + V +MR+K
Sbjct: 61 EKMWEQEEKMWEQQR-----LPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKT 115
Query: 635 EYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKNLGQPIKIRFQESEE 694
+ EK +++ K+++ E ++E E +Q +K+ E + + + + +E EE
Sbjct: 116 QEEKMQEQEE------KMQEQEEMMWEQEEKMQEQ--EEKMWEQEEKMREQEEKMREQEE 167
Query: 695 RPKLFEELGKQIQ 707
+ + EE + ++
Sbjct: 168 KMQGQEEKMRDVE 180
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 50.8 bits (120), Expect = 5e-06
Identities = 49/247 (19%), Positives = 111/247 (44%), Gaps = 27/247 (10%)
Query: 505 ENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEM--------------- 549
+ E+ E ++ +E+E+ QEE + EQ++ E + E EEM
Sbjct: 482 QEEKIREQEEKIREQEEKMWRQEEK-IHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWR 540
Query: 550 ---ETSQAGSKDKKMDQPPQAKKAKVKTSTVDLPIENQLLWQID---REMLNLYIENEGK 603
+ + K +K ++ ++ K+ + + + +W+ + RE E E K
Sbjct: 541 QKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEK 600
Query: 604 MIMQDKLEKERNDAKNAVEEYVYEMRDKLSGEYEKFVSEDDR-NSFTLKLEDTENWLYED 662
+ Q+++ +E+ + EE + E +K+ + EK ++++ K+ + E + E
Sbjct: 601 IREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIRE- 659
Query: 663 GEDQPKQVYVDKLAELKNLGQPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQ 722
+++ Q +K+ E + + + QE EE+ + EE K +Q +++ + ++
Sbjct: 660 -QEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEE--KMWEQEVRLRQQEEKMQEH 716
Query: 723 YDHLDAA 729
+HL+AA
Sbjct: 717 QEHLEAA 723
Score = 49.3 bits (116), Expect = 1e-05
Identities = 67/350 (19%), Positives = 155/350 (44%), Gaps = 30/350 (8%)
Query: 503 SEENEEPM--ETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKK 560
+++ EE M + ++ + EEK+Q +QEE E++++ E K +E + K ++
Sbjct: 356 NQQQEEKMWRQEEKIQEWEEKIQ-EQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRR 414
Query: 561 MDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKL----EKERND 616
++ K+ K++ + +++W+ + ++ L E KM Q+K+ EK + +
Sbjct: 415 QEEMMWEKEEKMRR-------QEEMMWEKEEKIREL----EEKMHEQEKIREQEEKRQEE 463
Query: 617 AKNAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDG-EDQPKQVYVDKL 675
K +E E K+ + EK ++++ ++ ++ + W E+ +Q K +K
Sbjct: 464 EKIREQEKRQEQEAKMWRQEEKIREQEEK----IREQEEKMWRQEEKIHEQEKIREEEKR 519
Query: 676 AELKNL-GQPIKIRFQES--EERPKLFEE---LGKQIQQYMKIISSFKNKEDQYDHLDAA 729
E + + Q KIR QE ++ K+ E+ + KQ ++ + ++E++ +
Sbjct: 520 QEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEK 579
Query: 730 DMTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKELTSTCSPIISKPKPK 789
+ EK + + + ++ ++ +T + K E E K+ E K + +
Sbjct: 580 VWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQ 639
Query: 790 VEPPKEEQKN-AEQNGPVDGQGDNPGPQAAEQGTDTAVPSDSDKKLPEMD 838
E +E++K EQ + Q + Q + + ++K+ E +
Sbjct: 640 EEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQE 689
Score = 48.5 bits (114), Expect = 3e-05
Identities = 28/135 (20%), Positives = 66/135 (48%), Gaps = 11/135 (8%)
Query: 504 EENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKKMDQ 563
E+ E+ E ++ +E+E+M +QEE E++++ E K + +E + + K ++ ++
Sbjct: 589 EQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEK 648
Query: 564 PPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAKNAVEE 623
+ ++ K++ + + + +W E E KM Q++ +E+ + EE
Sbjct: 649 KIREQEEKIREQEEMMQEQEEKMW-----------EQEEKMCEQEEKMQEQEEKMRRQEE 697
Query: 624 YVYEMRDKLSGEYEK 638
++E +L + EK
Sbjct: 698 KMWEQEVRLRQQEEK 712
Score = 47.4 bits (111), Expect = 6e-05
Identities = 59/284 (20%), Positives = 125/284 (44%), Gaps = 18/284 (6%)
Query: 502 KSEENEEPM-ETDQNAKEEEKMQVDQEEP--HVEEQQQQTPAENKAESEEMETSQAGSKD 558
K EE M E ++ + +E+M ++EE +EE+ + + E + E + ++
Sbjct: 411 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQE 470
Query: 559 KKMDQPPQ--AKKAKVKTSTVDLPIENQLLWQIDREMLNL-YIENEGKMIMQDKLEKERN 615
K+ +Q + ++ K++ + + + +W+ + ++ I E K Q++ E R
Sbjct: 471 KRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEK--RQEQEEMWRQ 528
Query: 616 DAKNAVEEYVYEMRDKLSGEYEKFVSEDDRN-SFTLKLEDTENWLYEDGEDQPKQVYVDK 674
+ K +E ++ ++K+ + EK ++++ K+ D E + E E +Q +
Sbjct: 529 EEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIR 588
Query: 675 LAELKNLGQPIKIRFQE---SEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAADM 731
E K Q KIR QE E+ K+ E+ K +Q K+ ++++ +
Sbjct: 589 EQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKM-----QEQEEKMRRQEEKI 643
Query: 732 TKVEKSTNEAMEWMNNKLNLQNKQSLTM-DPVVKSKEIEAKIKE 774
+ EK E E + + + +Q M + K E E K++E
Sbjct: 644 REQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE 687
Score = 30.4 bits (67), Expect = 7.1
Identities = 19/79 (24%), Positives = 39/79 (49%), Gaps = 1/79 (1%)
Query: 502 KSEENEEPMET-DQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKK 560
K +E EE M ++ +E+EK +QEE E+++ E K +E + + K ++
Sbjct: 628 KMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE 687
Query: 561 MDQPPQAKKAKVKTSTVDL 579
++ + ++ K+ V L
Sbjct: 688 QEEKMRRQEEKMWEQEVRL 706
>gi|8922950 meiosis-specific nuclear structural 1 [Homo sapiens]
Length = 495
Score = 49.7 bits (117), Expect = 1e-05
Identities = 70/322 (21%), Positives = 142/322 (44%), Gaps = 49/322 (15%)
Query: 500 VHKSEENEEPMETDQNAKEEEKMQVD----QEEPHVEEQQQQTPAENKAESEEMETSQAG 555
+ K+EEN+ E K+EEK+ ++ + E +E+ +Q EN E E+E
Sbjct: 73 IQKAEENKRLKELQ--LKQEEKLAMELAKLKHESLKDEKMRQQVRENSIELRELEKKLKA 130
Query: 556 SKDKKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDK-LEKER 614
+ K A+K +K + + D E+ +E ++I ++ E +R
Sbjct: 131 AYMNKERAAQIAEKDAIKYEQM----------KRDAEIAKTMMEEHKRIIKEENAAEDKR 180
Query: 615 NDAKNA----VEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQV 670
N AK +E+ + E K YE+ + E L +++ +YE+ + + +Q
Sbjct: 181 NKAKAQYYLDLEKQLEEQEKKKQEAYEQLLKE------KLMIDEIVRKIYEEDQLEKQQ- 233
Query: 671 YVDKLAELKNLGQPIKIRFQESEE--RPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDA 728
KL ++ + + I+ FQ+ + R K EE+ ++ ++ ++ + + +E+
Sbjct: 234 ---KLEKMNAMRRYIE-EFQKEQALWRKKKREEMEEENRKIIEFANMQQQREED------ 283
Query: 729 ADMTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKE-IEAKIKELTSTCSPIISKPK 787
M KV+++ + +L LQN + ++ +++ +E +E +EL I K K
Sbjct: 284 -RMAKVQENEEK-------RLQLQNALTQKLEEMLRQREDLEQVRQELYQEEQAEIYKSK 335
Query: 788 PKVEPPKEEQKNAEQNGPVDGQ 809
K E K+ +K E + Q
Sbjct: 336 LKEEAEKKLRKQKEMKQDFEEQ 357
Score = 37.7 bits (86), Expect = 0.045
Identities = 53/242 (21%), Positives = 101/242 (41%), Gaps = 35/242 (14%)
Query: 502 KSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKKM 561
K +ENEE QNA ++ ++ ++ +E+ +Q+ E +AE + SK K+
Sbjct: 287 KVQENEEKRLQLQNALTQKLEEMLRQREDLEQVRQELYQEEQAEIYK-------SKLKEE 339
Query: 562 DQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAKNAV 621
+ K+ ++K + +L+ Q +E EN K ++ E +R + NA
Sbjct: 340 AEKKLRKQKEMKQDFEEQMALKELVLQAAKE----EEENFRKTMLAKFAEDDRIELMNAQ 395
Query: 622 EEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKNL 681
++ + ++ + + EK + E + K + E W + Q +Q +++ + E
Sbjct: 396 KQRMKQLEHRRA--VEKLIEERRQQFLADKQRELEEWQLQ----QRRQGFINAIIE---- 445
Query: 682 GQPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAADMTKVEKSTNEA 741
EER KL +E + Y+ KED D L + KV + +E
Sbjct: 446 -----------EERLKLLKEHATNLLGYLP--KGVFKKEDDIDLL-GEEFRKVYQQRSEI 491
Query: 742 ME 743
E
Sbjct: 492 CE 493
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 48.9 bits (115), Expect = 2e-05
Identities = 66/353 (18%), Positives = 141/353 (39%), Gaps = 28/353 (7%)
Query: 504 EENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKKMDQ 563
E+ E+ E ++ + +E+M ++EE +++ E K +E + K ++ ++
Sbjct: 325 EQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEE 384
Query: 564 PPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYI-------ENEGKMIMQDKLEKERND 616
K+ K++ + + ++ Q ++ I E E KM Q++ +E+ +
Sbjct: 385 MMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEE 444
Query: 617 AKNAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLA 676
E+ ++ +K+ E EK E+ R E E W E+ + ++++ K
Sbjct: 445 KIREQEKKMWRQEEKIH-EQEKIREEEKRQ------EQEEMWRQEEKIHEQEEIWRQK-- 495
Query: 677 ELKNLGQPIKIRFQES----------EERPKLFEELGKQIQQYMKIISSFKNKEDQYDHL 726
K Q KIR QE E+ K+ E+ K +Q KI + ++
Sbjct: 496 -EKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMH 554
Query: 727 DAADMTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKELTSTCSPIISKP 786
+ + + EK + + + ++ ++ K +E E K +E K
Sbjct: 555 EQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKI 614
Query: 787 KPKVEPPKE-EQKNAEQNGPVDGQGDNPGPQAAEQGTDTAVPSDSDKKLPEMD 838
+ + E +E E+K EQ + Q + Q + G + ++K+ E +
Sbjct: 615 REQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQE 667
Score = 47.0 bits (110), Expect = 7e-05
Identities = 28/135 (20%), Positives = 65/135 (48%), Gaps = 11/135 (8%)
Query: 504 EENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKKMDQ 563
E+ E+ E ++ +E+E+M +QEE E++++ E K + +E + K ++ ++
Sbjct: 623 EQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEK 682
Query: 564 PPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAKNAVEE 623
+ ++ K++ + + + +W E E KM Q++ +E+ + EE
Sbjct: 683 KIREQEEKIREQEEMMQEQEEKMW-----------EQEEKMCEQEEKMQEQEEKMRRQEE 731
Query: 624 YVYEMRDKLSGEYEK 638
++E +L + EK
Sbjct: 732 KMWEQEVRLRQQEEK 746
Score = 46.2 bits (108), Expect = 1e-04
Identities = 65/277 (23%), Positives = 117/277 (42%), Gaps = 25/277 (9%)
Query: 505 ENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKKMDQP 564
+ E+ E ++ +E+EK QEE + EQ++ E + E EEM +++K+ +
Sbjct: 435 QEEKIREQEEKIREQEKKMWRQEEK-IHEQEKIREEEKRQEQEEM-----WRQEEKIHEQ 488
Query: 565 PQAKKAKVKTSTVDLPIENQ--LLWQID---REMLNLYIENEGKMIMQDKLEKERNDAKN 619
+ + K K + I Q +W+ + RE E E KM Q+ EK R +
Sbjct: 489 EEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQE--EKIREQEEM 546
Query: 620 AVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLAELK 679
EE ++K+ E ++ ED K+ + E ++ E +Q + E K
Sbjct: 547 WREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEK 606
Query: 680 NLGQPIKIRFQES--EERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAADMTKVEKS 737
Q KIR QE +E+ + E ++I++ ++ + K + + K+++
Sbjct: 607 MWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQ 666
Query: 738 TNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKE 774
E M K+ Q K K +E E KI+E
Sbjct: 667 -EETMWRQEEKIREQEK---------KIREQEEKIRE 693
Score = 45.8 bits (107), Expect = 2e-04
Identities = 42/197 (21%), Positives = 89/197 (45%), Gaps = 13/197 (6%)
Query: 499 EVHKSEENEEPM-ETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSK 557
E K +E E+ M ++ +E+E+ QEE E+++++ E K +E + + K
Sbjct: 561 EEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEK 620
Query: 558 DKKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDA 617
++ ++ + ++ K++ E + + Q E + E E KM Q++ +E+ +
Sbjct: 621 IQEQEEKIREQEEKIR--------EQEEMTQEQEEKMG---EQEEKMCEQEEKMQEQEET 669
Query: 618 KNAVEEYVYEMRDKLSGEYEKFVSEDD-RNSFTLKLEDTENWLYEDGEDQPKQVYVDKLA 676
EE + E K+ + EK +++ K+ + E + E E +Q +
Sbjct: 670 MWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQ 729
Query: 677 ELKNLGQPIKIRFQESE 693
E K Q +++R QE +
Sbjct: 730 EEKMWEQEVRLRQQEEK 746
Score = 45.1 bits (105), Expect = 3e-04
Identities = 60/294 (20%), Positives = 123/294 (41%), Gaps = 27/294 (9%)
Query: 502 KSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKKM 561
K E E+ E ++ +EEEK +QE+ +E + E E EE Q +KKM
Sbjct: 399 KMHEQEKIREQEEKRQEEEK-IREQEKRQEQEAKMWRQEEKIREQEEKIREQ----EKKM 453
Query: 562 DQPPQAKKAKVKTSTVDLPIENQLLWQID---REMLNLYIENEGKMIMQDKLEKERNDAK 618
+ + + K + E + +W+ + E ++ + E ++K+ K+
Sbjct: 454 WRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVW 513
Query: 619 NAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYED---GEDQPKQVYVDKL 675
EE + E +K+ + EK ++++ ++ E ++E E++ +Q DK+
Sbjct: 514 RQ-EEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKM 572
Query: 676 ---------AELKNLGQPIKIRFQE---SEERPKLF---EELGKQIQQYMKIISSFKNKE 720
E K Q KIR QE E+ K++ E++ +Q ++ + + +E
Sbjct: 573 WRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQE 632
Query: 721 DQYDHLDAADMTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKE 774
++ + + EK + + + +Q ++ K +E E KI+E
Sbjct: 633 EKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIRE 686
Score = 44.3 bits (103), Expect = 5e-04
Identities = 70/309 (22%), Positives = 131/309 (42%), Gaps = 56/309 (18%)
Query: 503 SEENEEPM--ETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKK 560
+++ EE M + ++ + EEK+Q +E+ +E++ + E EEM K++K
Sbjct: 295 NQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEM----MWEKEEK 350
Query: 561 MDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAKNA 620
M + + +++W E E KM Q+++ E+ +
Sbjct: 351 MRR------------------QEEMMW-----------EKEEKMRRQEEMMWEKEEKMRR 381
Query: 621 VEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKN 680
EE ++E +K+ EK ++ K+ + E E E++ ++ + E K
Sbjct: 382 QEEMMWEKEEKIRELEEKMHEQE-------KIREQEEKRQE--EEKIREQEKRQEQEAKM 432
Query: 681 LGQPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAADMTKVEKSTNE 740
Q KIR QE K+ E+ K +Q KI K +E++ + +M + E+ +E
Sbjct: 433 WRQEEKIREQEE----KIREQEKKMWRQEEKIHEQEKIREEE-KRQEQEEMWRQEEKIHE 487
Query: 741 AME-W-MNNKLNLQNKQSLTMDPVV-----KSKEIEAKIKELTSTCSPIISKPKPKVEPP 793
E W K++ Q ++ + V K +E E KI+E K + + E
Sbjct: 488 QEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMW 547
Query: 794 KEEQKNAEQ 802
+EE+K EQ
Sbjct: 548 REEEKMHEQ 556
Score = 44.3 bits (103), Expect = 5e-04
Identities = 57/290 (19%), Positives = 117/290 (40%), Gaps = 33/290 (11%)
Query: 502 KSEENEEPM-ETDQNAKEEEKMQVDQEEP--HVEEQQQQTPAENKAESEEMETSQAGSKD 558
K EE M E ++ + +E+M ++EE +EE+ + + E + E + ++
Sbjct: 364 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQE 423
Query: 559 KKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQD----KLEKER 614
K+ +Q + + + K RE E E KM Q+ + EK R
Sbjct: 424 KRQEQEAKMWRQEEKI----------------REQEEKIREQEKKMWRQEEKIHEQEKIR 467
Query: 615 NDAKNAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVDK 674
+ K +E ++ +K+ + E + ++ + K+ E ++ E +Q +
Sbjct: 468 EEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIR 527
Query: 675 LAELKNLGQPIKIRFQES--------EERPKLFEELGKQIQQ--YMKIISSFKNKEDQYD 724
E K Q KIR QE E+ K++EE +Q Q+ + + +E++
Sbjct: 528 EQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVW 587
Query: 725 HLDAADMTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKE 774
+ + EK + + + ++ ++ + K +E E KI+E
Sbjct: 588 RQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIRE 637
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.129 0.360
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,315,269
Number of Sequences: 37866
Number of extensions: 1474647
Number of successful extensions: 12633
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 201
Number of HSP's successfully gapped in prelim test: 540
Number of HSP's that attempted gapping in prelim test: 7884
Number of HSP's gapped (non-prelim): 3227
length of query: 840
length of database: 18,247,518
effective HSP length: 111
effective length of query: 729
effective length of database: 14,044,392
effective search space: 10238361768
effective search space used: 10238361768
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.