BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|38327039 heat shock 70kDa protein 4 [Homo sapiens] (840 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|38327039 heat shock 70kDa protein 4 [Homo sapiens] 1665 0.0 gi|31541941 heat shock 70kDa protein 4-like [Homo sapiens] 1088 0.0 gi|42544159 heat shock 105kD [Homo sapiens] 1082 0.0 gi|195976805 hypoxia up-regulated 1 precursor [Homo sapiens] 314 2e-85 gi|5453832 hypoxia up-regulated 1 precursor [Homo sapiens] 314 2e-85 gi|34419635 heat shock 70kDa protein 6 (HSP70B') [Homo sapiens] 301 2e-81 gi|167466173 heat shock 70kDa protein 1B [Homo sapiens] 294 3e-79 gi|194248072 heat shock 70kDa protein 1A [Homo sapiens] 294 3e-79 gi|124256496 heat shock 70kDa protein 1-like [Homo sapiens] 293 6e-79 gi|5729877 heat shock 70kDa protein 8 isoform 1 [Homo sapiens] 288 1e-77 gi|16507237 heat shock 70kDa protein 5 [Homo sapiens] 284 2e-76 gi|13676857 heat shock 70kDa protein 2 [Homo sapiens] 271 2e-72 gi|24234686 heat shock 70kDa protein 8 isoform 2 [Homo sapiens] 270 5e-72 gi|24234688 heat shock 70kDa protein 9 precursor [Homo sapiens] 219 8e-57 gi|82880658 heat shock 70kDa protein 14 isoform 1 [Homo sapiens] 191 2e-48 gi|48928056 heat shock protein 70kDa family member 13 precursor ... 163 7e-40 gi|221219020 NYD-SP11 protein [Homo sapiens] 60 1e-08 gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 60 1e-08 gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 60 1e-08 gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 59 1e-08 gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 58 3e-08 gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 55 2e-07 gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 55 3e-07 gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 54 5e-07 gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 53 1e-06 gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 52 2e-06 gi|239752551 PREDICTED: hypothetical protein [Homo sapiens] 52 2e-06 gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 51 5e-06 gi|8922950 meiosis-specific nuclear structural 1 [Homo sapiens] 50 1e-05 gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 49 2e-05 >gi|38327039 heat shock 70kDa protein 4 [Homo sapiens] Length = 840 Score = 1665 bits (4312), Expect = 0.0 Identities = 840/840 (100%), Positives = 840/840 (100%) Query: 1 MSVVGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISNA 60 MSVVGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISNA Sbjct: 1 MSVVGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISNA 60 Query: 61 KNTVQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTAM 120 KNTVQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTAM Sbjct: 61 KNTVQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTAM 120 Query: 121 LLSKLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVALA 180 LLSKLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVALA Sbjct: 121 LLSKLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVALA 180 Query: 181 YGIYKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVL 240 YGIYKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVL Sbjct: 181 YGIYKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVL 240 Query: 241 VNHFCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMNDVDVSGT 300 VNHFCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMNDVDVSGT Sbjct: 241 VNHFCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMNDVDVSGT 300 Query: 301 MNRGKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEKISKFFGK 360 MNRGKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEKISKFFGK Sbjct: 301 MNRGKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEKISKFFGK 360 Query: 361 ELSTTLNADEAVTRGCALQCAILSPAFKVREFSITDVVPYPISLRWNSPAEEGSSDCEVF 420 ELSTTLNADEAVTRGCALQCAILSPAFKVREFSITDVVPYPISLRWNSPAEEGSSDCEVF Sbjct: 361 ELSTTLNADEAVTRGCALQCAILSPAFKVREFSITDVVPYPISLRWNSPAEEGSSDCEVF 420 Query: 421 SKNHAAPFSKVLTFYRKEPFTLEAYYSSPQDLPYPDPAIAQFSVQKVTPQSDGSSSKVKV 480 SKNHAAPFSKVLTFYRKEPFTLEAYYSSPQDLPYPDPAIAQFSVQKVTPQSDGSSSKVKV Sbjct: 421 SKNHAAPFSKVLTFYRKEPFTLEAYYSSPQDLPYPDPAIAQFSVQKVTPQSDGSSSKVKV 480 Query: 481 KVRVNVHGIFSVSSASLVEVHKSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPA 540 KVRVNVHGIFSVSSASLVEVHKSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPA Sbjct: 481 KVRVNVHGIFSVSSASLVEVHKSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPA 540 Query: 541 ENKAESEEMETSQAGSKDKKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIEN 600 ENKAESEEMETSQAGSKDKKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIEN Sbjct: 541 ENKAESEEMETSQAGSKDKKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIEN 600 Query: 601 EGKMIMQDKLEKERNDAKNAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLY 660 EGKMIMQDKLEKERNDAKNAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLY Sbjct: 601 EGKMIMQDKLEKERNDAKNAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLY 660 Query: 661 EDGEDQPKQVYVDKLAELKNLGQPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKE 720 EDGEDQPKQVYVDKLAELKNLGQPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKE Sbjct: 661 EDGEDQPKQVYVDKLAELKNLGQPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKE 720 Query: 721 DQYDHLDAADMTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKELTSTCS 780 DQYDHLDAADMTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKELTSTCS Sbjct: 721 DQYDHLDAADMTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKELTSTCS 780 Query: 781 PIISKPKPKVEPPKEEQKNAEQNGPVDGQGDNPGPQAAEQGTDTAVPSDSDKKLPEMDID 840 PIISKPKPKVEPPKEEQKNAEQNGPVDGQGDNPGPQAAEQGTDTAVPSDSDKKLPEMDID Sbjct: 781 PIISKPKPKVEPPKEEQKNAEQNGPVDGQGDNPGPQAAEQGTDTAVPSDSDKKLPEMDID 840 >gi|31541941 heat shock 70kDa protein 4-like [Homo sapiens] Length = 839 Score = 1088 bits (2813), Expect = 0.0 Identities = 541/853 (63%), Positives = 669/853 (78%), Gaps = 27/853 (3%) Query: 1 MSVVGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISNA 60 MSVVGIDLGF +CY+AVAR+GGIETIANEYSDRCTPACIS G + R+IG AAKSQ+++N Sbjct: 1 MSVVGIDLGFLNCYIAVARSGGIETIANEYSDRCTPACISLGSRTRAIGNAAKSQIVTNV 60 Query: 61 KNTVQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTAM 120 +NT+ GFK+ HGR+F DP V+ E+ L Y++ ++P G G+KV Y+EEER F EQVT M Sbjct: 61 RNTIHGFKKLHGRSFDDPIVQTERIRLPYELQKMPNGSAGVKVRYLEEERPFAIEQVTGM 120 Query: 121 LLSKLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVALA 180 LL+KLKET+E+ LKKPV DCV+S+P F+TDAERRSVM A Q+AGLNCLRLMNETTAVALA Sbjct: 121 LLAKLKETSENALKKPVADCVISIPSFFTDAERRSVMAAAQVAGLNCLRLMNETTAVALA 180 Query: 181 YGIYKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVL 240 YGIYKQDLP L+EKPRNVVF+DMGHSAYQV VCAFN+GKLKVLAT FD LGGR FDE L Sbjct: 181 YGIYKQDLPPLDEKPRNVVFIDMGHSAYQVLVCAFNKGKLKVLATTFDPYLGGRNFDEAL 240 Query: 241 VNHFCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMNDVDVSGT 300 V++FC+EF KYK+++K RALLRL QECEKLKKLMSANASDLPL+IECFMND+DVS Sbjct: 241 VDYFCDEFKTKYKINVKENSRALLRLYQECEKLKKLMSANASDLPLNIECFMNDLDVSSK 300 Query: 301 MNRGKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEKISKFFGK 360 MNR +F ++C LLARVEPPL++V+EQ L++EDI ++EIVGGATRIPAVKE+I+KFF K Sbjct: 301 MNRAQFEQLCASLLARVEPPLKAVMEQANLQREDISSIEIVGGATRIPAVKEQITKFFLK 360 Query: 361 ELSTTLNADEAVTRGCALQCAILSPAFKVREFSITDVVPYPISLRWNSPAEEGSSDCEVF 420 ++STTLNADEAV RGCALQCAILSPAFKVREFSITD+VPY I+LRW + E+GS +CEVF Sbjct: 361 DISTTLNADEAVARGCALQCAILSPAFKVREFSITDLVPYSITLRWKTSFEDGSGECEVF 420 Query: 421 SKNHAAPFSKVLTFYRKEPFTLEAYYSSPQDLPYPDPAIAQFSVQKVTPQSDGSSSKVKV 480 KNH APFSKV+TF++KEPF LEA+Y++ ++PYPD I F++Q V PQSDG SSKVKV Sbjct: 421 CKNHPAPFSKVITFHKKEPFELEAFYTNLHEVPYPDARIGSFTIQNVFPQSDGDSSKVKV 480 Query: 481 KVRVNVHGIFSVSSASLVEVH--KSEENEEPMETDQNAKEE-----EKMQVDQEEPHVEE 533 KVRVN+HGIFSV+SAS++E + + ++ PMET+ + K E +KMQVDQEE H + Sbjct: 481 KVRVNIHGIFSVASASVIEKQNLEGDHSDAPMETETSFKNENKDNMDKMQVDQEEGHQKC 540 Query: 534 QQQQTPAENKAESEEMETSQAGSKDKKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREM 593 + TP E + S K +++Q KK KVK ++DLPI++ L Q+ +++ Sbjct: 541 HAEHTPEEEIDHTGAKTKSAVSDKQDRLNQ--TLKKGKVK--SIDLPIQSSLCRQLGQDL 596 Query: 594 LNLYIENEGKMIMQDKLEKERNDAKNAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLE 653 LN YIENEGKMIMQDKLEKERNDAKNAVEEYVY+ RD+L YEKF++ +D + + LE Sbjct: 597 LNSYIENEGKMIMQDKLEKERNDAKNAVEEYVYDFRDRLGTVYEKFITPEDLSKLSAVLE 656 Query: 654 DTENWLYEDGEDQPKQVYVDKLAELKNLGQPIKIRFQESEERPKLFEELGKQIQQYMKII 713 DTENWLYEDGEDQPKQVYVDKL ELK GQPI++++ E EERPK +LGK+IQ MK+I Sbjct: 657 DTENWLYEDGEDQPKQVYVDKLQELKKYGQPIQMKYMEHEERPKALNDLGKKIQLVMKVI 716 Query: 714 SSFKNKEDQYDHLDAADMTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIK 773 +++NK+++YDHLD +M KVEK ++AM W+N+K+N QNK SLT DPVVK EI AK K Sbjct: 717 EAYRNKDERYDHLDPTEMEKVEKCISDAMSWLNSKMNAQNKLSLTQDPVVKVSEIVAKSK 776 Query: 774 ELTSTCSPIISKPKPKVEPPKEEQK-NAEQNGPVDGQGDNPGPQAAEQGTDTAVPSDSD- 831 EL + C+PII KPKPK E P+++ K N+E NGP+DGQ GT+T S D Sbjct: 777 ELDNFCNPIIYKPKPKAEVPEDKPKANSEHNGPMDGQ----------SGTETKSDSTKDS 826 Query: 832 ----KKLPEMDID 840 K EM++D Sbjct: 827 SQHTKSSGEMEVD 839 >gi|42544159 heat shock 105kD [Homo sapiens] Length = 858 Score = 1082 bits (2798), Expect = 0.0 Identities = 539/822 (65%), Positives = 652/822 (79%), Gaps = 20/822 (2%) Query: 1 MSVVGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISNA 60 MSVVG+D+G QSCY+AVARAGGIETIANE+SDRCTP+ ISFG KNR+IG AAK+Q I++A Sbjct: 1 MSVVGLDVGSQSCYIAVARAGGIETIANEFSDRCTPSVISFGSKNRTIGVAAKNQQITHA 60 Query: 61 KNTVQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTAM 120 NTV FKRFHGRAF+DPF++ EK NL+YD+V L G GIKV YM EE F+ EQ+TAM Sbjct: 61 NNTVSNFKRFHGRAFNDPFIQKEKENLSYDLVPLKNGGVGIKVMYMGEEHLFSVEQITAM 120 Query: 121 LLSKLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVALA 180 LL+KLKETAE+ LKKPV DCV+SVP F+TDAERRSV+DA QI GLNCLRLMN+ TAVAL Sbjct: 121 LLTKLKETAENSLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMNDMTAVALN 180 Query: 181 YGIYKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVL 240 YGIYKQDLP+L+EKPR VVFVDMGHSA+QVS CAFN+GKLKVL TAFD LGG+ FDE L Sbjct: 181 YGIYKQDLPSLDEKPRIVVFVDMGHSAFQVSACAFNKGKLKVLGTAFDPFLGGKNFDEKL 240 Query: 241 VNHFCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMNDVDVSGT 300 V HFC EF KYKLD KSKIRALLRL QECEKLKKLMS+N++DLPL+IECFMND DVSG Sbjct: 241 VEHFCAEFKTKYKLDAKSKIRALLRLYQECEKLKKLMSSNSTDLPLNIECFMNDKDVSGK 300 Query: 301 MNRGKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEKISKFFGK 360 MNR +F E+C +LL ++E PL S+LEQT LK ED+ AVEIVGGATRIPAVKE+I+KFFGK Sbjct: 301 MNRSQFEELCAELLQKIEVPLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAKFFGK 360 Query: 361 ELSTTLNADEAVTRGCALQCAILSPAFKVREFSITDVVPYPISLRWNSPAEEGSSDCEVF 420 ++STTLNADEAV RGCALQCAILSPAFKVREFS+TD VP+PISL WN +E+ EVF Sbjct: 361 DISTTLNADEAVARGCALQCAILSPAFKVREFSVTDAVPFPISLIWNHDSEDTEGVHEVF 420 Query: 421 SKNHAAPFSKVLTFYRKEPFTLEAYYSSPQDLPYPDPAIAQFSVQKVTPQSDGSSSKVKV 480 S+NHAAPFSKVLTF R+ PF LEA+YS PQ +PYP+ I +F VQ V+ Q DG S+VKV Sbjct: 421 SRNHAAPFSKVLTFLRRGPFELEAFYSDPQGVPYPEAKIGRFVVQNVSAQKDGEKSRVKV 480 Query: 481 KVRVNVHGIFSVSSASLVEVHKSEENEEPMETD---------QNAKEEEKMQVDQEE--- 528 KVRVN HGIF++S+AS+VE +EENE E D +N ++ +Q D E Sbjct: 481 KVRVNTHGIFTISTASMVEKVPTEENEMSSEADMECLNQRPPENPDTDKNVQQDNSEAGT 540 Query: 529 -PHVEEQQQQT---PAENKAESEEMETSQAG-SKDKKMDQPPQAKKAKVKTSTVDLPIEN 583 P V+ QQT P + SEE + A + +KK+DQPP+AKK K+K V+LPIE Sbjct: 541 QPQVQTDAQQTSQSPPSPELTSEENKIPDADKANEKKVDQPPEAKKPKIKVVNVELPIEA 600 Query: 584 QLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAKNAVEEYVYEMRDKLSGEYEKFVSED 643 L+WQ+ +++LN+YIE EGKMIMQDKLEKERNDAKNAVEEYVYE RDKL G YEKF+ E Sbjct: 601 NLVWQLGKDLLNMYIETEGKMIMQDKLEKERNDAKNAVEEYVYEFRDKLCGPYEKFICEQ 660 Query: 644 DRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKNLGQPIKIRFQESEERPKLFEELG 703 D +F L +TE+WLYE+GEDQ KQ YVDKL EL +G P+K+RFQE+EERPK+FEELG Sbjct: 661 DHQNFLRLLTETEDWLYEEGEDQAKQAYVDKLEELMKIGTPVKVRFQEAEERPKMFEELG 720 Query: 704 KQIQQYMKIISSFKNKEDQYDHLDAADMTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVV 763 +++Q Y KI + F+NK+++Y+H+D ++M KVEKS NE MEWMNN +N Q K+SL DPVV Sbjct: 721 QRLQHYAKIAADFRNKDEKYNHIDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLDQDPVV 780 Query: 764 KSKEIEAKIKELTSTCSPIISKPKPKVEPPKEEQKNAEQNGP 805 +++EI+ KIKEL +TC P++++PKPK+E PK E+ NGP Sbjct: 781 RAQEIKTKIKELNNTCEPVVTQPKPKIESPKLER---TPNGP 819 >gi|195976805 hypoxia up-regulated 1 precursor [Homo sapiens] Length = 999 Score = 314 bits (805), Expect = 2e-85 Identities = 257/939 (27%), Positives = 425/939 (45%), Gaps = 116/939 (12%) Query: 1 MSVVGIDLGFQSCYVAVARAG-GIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISN 59 ++V+ +DLG +S VA+ + G +E + N+ S R TP ++ R G +A S I N Sbjct: 33 LAVMSVDLGSESMKVAIVKPGVPMEIVLNKESRRKTPVIVTLKENERFFGDSAASMAIKN 92 Query: 60 AKNTVQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTA 119 K T++ F+ G+ +P V ++ + + + + F+ E+V Sbjct: 93 PKATLRYFQHLLGKQADNPHVALYQARFPEHELTFDPQRQTVHFQ-ISSQLQFSPEEVLG 151 Query: 120 MLLSKLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVAL 179 M+L+ + AE ++P+ D V++VP F+ AERR+V+ A ++AGL L+L+N+ TA AL Sbjct: 152 MVLNYSRSLAEDFAEQPIKDAVITVPVFFNQAERRAVLQAARMAGLKVLQLINDNTATAL 211 Query: 180 AYGIYKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGK---------LKVLATAFDTT 230 +YG++++ + +N++F DMG + ++ + K L++ FD T Sbjct: 212 SYGVFRR--KDINTTAQNIMFYDMGSGSTVCTIVTYQMVKTKEAGMQPQLQIRGVGFDRT 269 Query: 231 LGGRKFD----EVLVNHFCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPL 286 LGG + + E L F E+ + D++ RA+ +L +E +LK ++SANA D Sbjct: 270 LGGLEMELRLRERLAGLFNEQRKGQRAKDVRENPRAMAKLLREANRLKTVLSANA-DHMA 328 Query: 287 SIECFMNDVDVSGTMNRGKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATR 346 IE M+DVD + R +F E+C DL RV P++ L+ ++ ++I V +VGGATR Sbjct: 329 QIEGLMDDVDFKAKVTRVEFEELCADLFERVPGPVQQALQSAEMSLDEIEQVILVGGATR 388 Query: 347 IPAVKEKISKFFGK-ELSTTLNADEAVTRGCALQCAILSPAFKVREFSITDVVPYPISLR 405 +P V+E + K GK EL +NADEA G Q A LS AFKV+ F + D V YPI + Sbjct: 389 VPRVQEVLLKAVGKEELGKNINADEAAAMGAVYQAAALSKAFKVKPFVVRDAVVYPILVE 448 Query: 406 WNSPAEE-------GSSDCEVFSKNHAAPFSKVLTFYR-KEPFTLEAYYSSPQDLPYPDP 457 + EE + +FS+ P KV+TF R F Y DL + P Sbjct: 449 FTREVEEEPGIHSLKHNKRVLFSRMGPYPQRKVITFNRYSHDFNFHINYG---DLGFLGP 505 Query: 458 A-IAQFSVQKVT------------PQSDGSSSKVKVKVRVNVHGIFSVSSA-----SLVE 499 + F Q +T D S +K ++ G+ S+ +LVE Sbjct: 506 EDLRVFGSQNLTTVKLKGVGDSFKKYPDYESKGIKAHFNLDESGVLSLDRVESVFETLVE 565 Query: 500 VHKSEEN------------------------------EEPMETDQNAKEEEKMQV---DQ 526 EE+ EE + +K+E QV ++ Sbjct: 566 DSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDTVQEEEESPAEGSKDEPGEQVELKEE 625 Query: 527 EEPHVEEQQQQTPAENK----------AESEEMETSQAGSKDKKMD-------------- 562 E VE+ Q P E K E E + S+A +K + Sbjct: 626 AEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDKSEAQKPSEKAEAGPEGVAPAPEGEK 685 Query: 563 -QPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAKNAV 621 Q P K+ V+ V+L + + L + + L ++ + ++D ++ER A N++ Sbjct: 686 KQKPARKRRMVEEIGVELVVLD--LPDLPEDKLAQSVQKLQDLTLRDLEKQEREKAANSL 743 Query: 622 EEYVYEMRDKL-SGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKN 680 E +++E +DKL EY++ +E+ R + KL WL ++G + +KLAEL+ Sbjct: 744 EAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAASTWLEDEGVGATTVMLKEKLAELRK 803 Query: 681 LGQPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAADMTKVEKSTNE 740 L Q + R +E ++ P+ L + + + + +MT +EK NE Sbjct: 804 LCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGARLIPEMDQIFTEVEMTTLEKVINE 863 Query: 741 AMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKELTSTCSPIISKPKPKVEPPKEEQKNA 800 W N L Q K T PV+ SK+IEAK+ L +++K K P+ + KN Sbjct: 864 TWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDREVQYLLNKAKFTKPRPRPKDKNG 923 Query: 801 EQ-----NGPVDGQGDNPGPQAAEQGTDTAVPSDSDKKL 834 + N QG+ P A + T+ A P +K+ Sbjct: 924 TRAEPPLNASASDQGEKVIPPAGQ--TEDAEPISEPEKV 960 >gi|5453832 hypoxia up-regulated 1 precursor [Homo sapiens] Length = 999 Score = 314 bits (805), Expect = 2e-85 Identities = 257/939 (27%), Positives = 425/939 (45%), Gaps = 116/939 (12%) Query: 1 MSVVGIDLGFQSCYVAVARAG-GIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISN 59 ++V+ +DLG +S VA+ + G +E + N+ S R TP ++ R G +A S I N Sbjct: 33 LAVMSVDLGSESMKVAIVKPGVPMEIVLNKESRRKTPVIVTLKENERFFGDSAASMAIKN 92 Query: 60 AKNTVQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTA 119 K T++ F+ G+ +P V ++ + + + + F+ E+V Sbjct: 93 PKATLRYFQHLLGKQADNPHVALYQARFPEHELTFDPQRQTVHFQ-ISSQLQFSPEEVLG 151 Query: 120 MLLSKLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVAL 179 M+L+ + AE ++P+ D V++VP F+ AERR+V+ A ++AGL L+L+N+ TA AL Sbjct: 152 MVLNYSRSLAEDFAEQPIKDAVITVPVFFNQAERRAVLQAARMAGLKVLQLINDNTATAL 211 Query: 180 AYGIYKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGK---------LKVLATAFDTT 230 +YG++++ + +N++F DMG + ++ + K L++ FD T Sbjct: 212 SYGVFRR--KDINTTAQNIMFYDMGSGSTVCTIVTYQMVKTKEAGMQPQLQIRGVGFDRT 269 Query: 231 LGGRKFD----EVLVNHFCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPL 286 LGG + + E L F E+ + D++ RA+ +L +E +LK ++SANA D Sbjct: 270 LGGLEMELRLRERLAGLFNEQRKGQRAKDVRENPRAMAKLLREANRLKTVLSANA-DHMA 328 Query: 287 SIECFMNDVDVSGTMNRGKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATR 346 IE M+DVD + R +F E+C DL RV P++ L+ ++ ++I V +VGGATR Sbjct: 329 QIEGLMDDVDFKAKVTRVEFEELCADLFERVPGPVQQALQSAEMSLDEIEQVILVGGATR 388 Query: 347 IPAVKEKISKFFGK-ELSTTLNADEAVTRGCALQCAILSPAFKVREFSITDVVPYPISLR 405 +P V+E + K GK EL +NADEA G Q A LS AFKV+ F + D V YPI + Sbjct: 389 VPRVQEVLLKAVGKEELGKNINADEAAAMGAVYQAAALSKAFKVKPFVVRDAVVYPILVE 448 Query: 406 WNSPAEE-------GSSDCEVFSKNHAAPFSKVLTFYR-KEPFTLEAYYSSPQDLPYPDP 457 + EE + +FS+ P KV+TF R F Y DL + P Sbjct: 449 FTREVEEEPGIHSLKHNKRVLFSRMGPYPQRKVITFNRYSHDFNFHINYG---DLGFLGP 505 Query: 458 A-IAQFSVQKVT------------PQSDGSSSKVKVKVRVNVHGIFSVSSA-----SLVE 499 + F Q +T D S +K ++ G+ S+ +LVE Sbjct: 506 EDLRVFGSQNLTTVKLKGVGDSFKKYPDYESKGIKAHFNLDESGVLSLDRVESVFETLVE 565 Query: 500 VHKSEEN------------------------------EEPMETDQNAKEEEKMQV---DQ 526 EE+ EE + +K+E QV ++ Sbjct: 566 DSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDTVQEEEESPAEGSKDEPGEQVELKEE 625 Query: 527 EEPHVEEQQQQTPAENK----------AESEEMETSQAGSKDKKMD-------------- 562 E VE+ Q P E K E E + S+A +K + Sbjct: 626 AEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDKSEAQKPSEKAEAGPEGVAPAPEGEK 685 Query: 563 -QPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAKNAV 621 Q P K+ V+ V+L + + L + + L ++ + ++D ++ER A N++ Sbjct: 686 KQKPARKRRMVEEIGVELVVLD--LPDLPEDKLAQSVQKLQDLTLRDLEKQEREKAANSL 743 Query: 622 EEYVYEMRDKL-SGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKN 680 E +++E +DKL EY++ +E+ R + KL WL ++G + +KLAEL+ Sbjct: 744 EAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAASTWLEDEGVGATTVMLKEKLAELRK 803 Query: 681 LGQPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAADMTKVEKSTNE 740 L Q + R +E ++ P+ L + + + + +MT +EK NE Sbjct: 804 LCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGARLIPEMDQIFTEVEMTTLEKVINE 863 Query: 741 AMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKELTSTCSPIISKPKPKVEPPKEEQKNA 800 W N L Q K T PV+ SK+IEAK+ L +++K K P+ + KN Sbjct: 864 TWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDREVQYLLNKAKFTKPRPRPKDKNG 923 Query: 801 EQ-----NGPVDGQGDNPGPQAAEQGTDTAVPSDSDKKL 834 + N QG+ P A + T+ A P +K+ Sbjct: 924 TRAEPPLNASASDQGEKVIPPAGQ--TEDAEPISEPEKV 960 >gi|34419635 heat shock 70kDa protein 6 (HSP70B') [Homo sapiens] Length = 643 Score = 301 bits (770), Expect = 2e-81 Identities = 191/581 (32%), Positives = 310/581 (53%), Gaps = 27/581 (4%) Query: 4 VGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISNAKNT 63 VGIDLG V V + G +E +AN+ +R TP+ ++F R +G AAKSQ N NT Sbjct: 9 VGIDLGTTYSCVGVFQQGRVEILANDQGNRTTPSYVAFTDTERLVGDAAKSQAALNPHNT 68 Query: 64 VQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTAMLLS 123 V KR GR F+D V+++ + + +V G ++V Y E++ F E++++M+LS Sbjct: 69 VFDAKRLIGRKFADTTVQSDMKHWPFRVVS-EGGKPKVRVCYRGEDKTFYPEEISSMVLS 127 Query: 124 KLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVALAYGI 183 K+KETAE+ L +PV V++VP ++ D++R++ DA IAGLN LR++NE TA A+AYG+ Sbjct: 128 KMKETAEAYLGQPVKHAVITVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGL 187 Query: 184 YKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVLVNH 243 ++ RNV+ D+G + VSV + + G +V ATA DT LGG FD LVNH Sbjct: 188 DRRG-----AGERNVLIFDLGGGTFDVSVLSIDAGVFEVKATAGDTHLGGEDFDNRLVNH 242 Query: 244 FCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMNDVDVSGTMNR 303 F EEF +K+ D+ RAL RL CE+ K+ +S +++ L I+ VD ++ R Sbjct: 243 FMEEFRRKHGKDLSGNKRALRRLRTACERAKRTLS-SSTQATLEIDSLFEGVDFYTSITR 301 Query: 304 GKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEKISKFF-GKEL 362 +F E+C+DL P+ L KL K I+ V +VGG+TRIP V++ + FF GKEL Sbjct: 302 ARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDVVLVGGSTRIPKVQKLLQDFFNGKEL 361 Query: 363 STTLNADEAVTRGCALQCAIL--SPAFKVREFSITDVVPYPISLRWNSPAEEGSSDCEVF 420 + ++N DEAV G A+Q A+L KV++ + DV P + L G + Sbjct: 362 NKSINPDEAVAYGAAVQAAVLMGDKCEKVQDLLLLDVAPLSLGLE-----TAGGVMTTLI 416 Query: 421 SKNHAAPFSKVLTFYR---KEPFTLEAYYSSPQDLPYPDPAIAQFSVQKVTPQSDGSSSK 477 +N P + TF +P Y + + + + +F + + P G + Sbjct: 417 QRNATIPTKQTQTFTTYSDNQPGVFIQVYEGERAMTKDNNLLGRFELSGIPPAPRG-VPQ 475 Query: 478 VKVKVRVNVHGIFSVSSASLVEVHKSEENEEPMETDQN--AKEEEKMQVDQEEPHV---E 532 ++V ++ +GI SV++ + + N+ + D+ +KEE + V + E + E Sbjct: 476 IEVTFDIDANGILSVTA---TDRSTGKANKITITNDKGRLSKEEVERMVHEAEQYKAEDE 532 Query: 533 EQQQQTPAENKAESEEMETSQAGSKDKKMDQPPQAKKAKVK 573 Q+ + A+N E+ + ++ D+ P+ + K++ Sbjct: 533 AQRDRVAAKNSLEAHVFHVKGSLQEESLRDKIPEEDRRKMQ 573 >gi|167466173 heat shock 70kDa protein 1B [Homo sapiens] Length = 641 Score = 294 bits (752), Expect = 3e-79 Identities = 188/582 (32%), Positives = 309/582 (53%), Gaps = 27/582 (4%) Query: 2 SVVGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISNAK 61 + +GIDLG V V + G +E IAN+ +R TP+ ++F R IG AAK+QV N + Sbjct: 5 AAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQ 64 Query: 62 NTVQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTAML 121 NTV KR GR F DP V+++ + + ++ ++V+Y E + F E++++M+ Sbjct: 65 NTVFDAKRLIGRKFGDPVVQSDMKHWPFQVIN-DGDKPKVQVSYKGETKAFYPEEISSMV 123 Query: 122 LSKLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVALAY 181 L+K+KE AE+ L PV + V++VP ++ D++R++ DA IAGLN LR++NE TA A+AY Sbjct: 124 LTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAY 183 Query: 182 GIYKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVLV 241 G L + RNV+ D+G + VS+ + G +V ATA DT LGG FD LV Sbjct: 184 G-----LDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLV 238 Query: 242 NHFCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMNDVDVSGTM 301 NHF EEF +K+K DI RA+ RL CE+ K+ +S +++ L I+ +D ++ Sbjct: 239 NHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLS-SSTQASLEIDSLFEGIDFYTSI 297 Query: 302 NRGKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEKISKFF-GK 360 R +F E+C+DL P+ L KL K I+ + +VGG+TRIP V++ + FF G+ Sbjct: 298 TRARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGR 357 Query: 361 ELSTTLNADEAVTRGCALQCAIL--SPAFKVREFSITDVVPYPISLRWNSPAEEGSSDCE 418 +L+ ++N DEAV G A+Q AIL + V++ + DV P + L G Sbjct: 358 DLNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLE-----TAGGVMTA 412 Query: 419 VFSKNHAAPFSKV---LTFYRKEPFTLEAYYSSPQDLPYPDPAIAQFSVQKVTPQSDGSS 475 + +N P + T+ +P L Y + + + + +F + + P G Sbjct: 413 LIKRNSTIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPRG-V 471 Query: 476 SKVKVKVRVNVHGIFSVSSASLVEVHKSEENEEPMETDQN--AKEEEKMQVDQEEPHVEE 533 +++V ++ +GI +V++ + + N+ + D+ +KEE + V + E + E Sbjct: 472 PQIEVTFDIDANGILNVTA---TDKSTGKANKITITNDKGRLSKEEIERMVQEAEKYKAE 528 Query: 534 ---QQQQTPAENKAESEEMETSQAGSKDKKMDQPPQAKKAKV 572 Q+++ A+N ES A + + +A K KV Sbjct: 529 DEVQRERVSAKNALESYAFNMKSAVEDEGLKGKISEADKKKV 570 Score = 42.4 bits (98), Expect = 0.002 Identities = 26/99 (26%), Positives = 50/99 (50%), Gaps = 2/99 (2%) Query: 588 QIDREMLNLYIENEGKMIMQDKLEKERNDAKNAVEEYVYEMRDKLSGEYEK-FVSEDDRN 646 ++ +E + ++ K +D++++ER AKNA+E Y + M+ + E K +SE D+ Sbjct: 509 RLSKEEIERMVQEAEKYKAEDEVQRERVSAKNALESYAFNMKSAVEDEGLKGKISEADKK 568 Query: 647 SFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKNLGQPI 685 K ++ +WL + K + K EL+ + PI Sbjct: 569 KVLDKCQEVISWL-DANTLAEKDEFEHKRKELEQVCNPI 606 Score = 31.6 bits (70), Expect = 3.2 Identities = 31/133 (23%), Positives = 49/133 (36%), Gaps = 21/133 (15%) Query: 688 RFQESEERPKLFEELGKQ-------IQQYMKIISSFKNKEDQYDHLDAADMTKVEKSTNE 740 R + E+ K +E+ ++ ++ Y + S E + AD KV E Sbjct: 517 RMVQEAEKYKAEDEVQRERVSAKNALESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQE 576 Query: 741 AMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKELTSTCSPIISKPKPKVEPPKEEQKNA 800 + W++ + + + E E K KEL C+PIIS P A Sbjct: 577 VISWLD------------ANTLAEKDEFEHKRKELEQVCNPIISGLYQGAGGPGPGGFGA 624 Query: 801 EQNGPVDGQGDNP 813 + GP G G P Sbjct: 625 Q--GPKGGSGSGP 635 >gi|194248072 heat shock 70kDa protein 1A [Homo sapiens] Length = 641 Score = 294 bits (752), Expect = 3e-79 Identities = 188/582 (32%), Positives = 309/582 (53%), Gaps = 27/582 (4%) Query: 2 SVVGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISNAK 61 + +GIDLG V V + G +E IAN+ +R TP+ ++F R IG AAK+QV N + Sbjct: 5 AAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQ 64 Query: 62 NTVQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTAML 121 NTV KR GR F DP V+++ + + ++ ++V+Y E + F E++++M+ Sbjct: 65 NTVFDAKRLIGRKFGDPVVQSDMKHWPFQVIN-DGDKPKVQVSYKGETKAFYPEEISSMV 123 Query: 122 LSKLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVALAY 181 L+K+KE AE+ L PV + V++VP ++ D++R++ DA IAGLN LR++NE TA A+AY Sbjct: 124 LTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAY 183 Query: 182 GIYKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVLV 241 G L + RNV+ D+G + VS+ + G +V ATA DT LGG FD LV Sbjct: 184 G-----LDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLV 238 Query: 242 NHFCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMNDVDVSGTM 301 NHF EEF +K+K DI RA+ RL CE+ K+ +S +++ L I+ +D ++ Sbjct: 239 NHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLS-SSTQASLEIDSLFEGIDFYTSI 297 Query: 302 NRGKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEKISKFF-GK 360 R +F E+C+DL P+ L KL K I+ + +VGG+TRIP V++ + FF G+ Sbjct: 298 TRARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGR 357 Query: 361 ELSTTLNADEAVTRGCALQCAIL--SPAFKVREFSITDVVPYPISLRWNSPAEEGSSDCE 418 +L+ ++N DEAV G A+Q AIL + V++ + DV P + L G Sbjct: 358 DLNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLE-----TAGGVMTA 412 Query: 419 VFSKNHAAPFSKV---LTFYRKEPFTLEAYYSSPQDLPYPDPAIAQFSVQKVTPQSDGSS 475 + +N P + T+ +P L Y + + + + +F + + P G Sbjct: 413 LIKRNSTIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPRG-V 471 Query: 476 SKVKVKVRVNVHGIFSVSSASLVEVHKSEENEEPMETDQN--AKEEEKMQVDQEEPHVEE 533 +++V ++ +GI +V++ + + N+ + D+ +KEE + V + E + E Sbjct: 472 PQIEVTFDIDANGILNVTA---TDKSTGKANKITITNDKGRLSKEEIERMVQEAEKYKAE 528 Query: 534 ---QQQQTPAENKAESEEMETSQAGSKDKKMDQPPQAKKAKV 572 Q+++ A+N ES A + + +A K KV Sbjct: 529 DEVQRERVSAKNALESYAFNMKSAVEDEGLKGKISEADKKKV 570 Score = 42.4 bits (98), Expect = 0.002 Identities = 26/99 (26%), Positives = 50/99 (50%), Gaps = 2/99 (2%) Query: 588 QIDREMLNLYIENEGKMIMQDKLEKERNDAKNAVEEYVYEMRDKLSGEYEK-FVSEDDRN 646 ++ +E + ++ K +D++++ER AKNA+E Y + M+ + E K +SE D+ Sbjct: 509 RLSKEEIERMVQEAEKYKAEDEVQRERVSAKNALESYAFNMKSAVEDEGLKGKISEADKK 568 Query: 647 SFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKNLGQPI 685 K ++ +WL + K + K EL+ + PI Sbjct: 569 KVLDKCQEVISWL-DANTLAEKDEFEHKRKELEQVCNPI 606 Score = 31.6 bits (70), Expect = 3.2 Identities = 31/133 (23%), Positives = 49/133 (36%), Gaps = 21/133 (15%) Query: 688 RFQESEERPKLFEELGKQ-------IQQYMKIISSFKNKEDQYDHLDAADMTKVEKSTNE 740 R + E+ K +E+ ++ ++ Y + S E + AD KV E Sbjct: 517 RMVQEAEKYKAEDEVQRERVSAKNALESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQE 576 Query: 741 AMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKELTSTCSPIISKPKPKVEPPKEEQKNA 800 + W++ + + + E E K KEL C+PIIS P A Sbjct: 577 VISWLD------------ANTLAEKDEFEHKRKELEQVCNPIISGLYQGAGGPGPGGFGA 624 Query: 801 EQNGPVDGQGDNP 813 + GP G G P Sbjct: 625 Q--GPKGGSGSGP 635 >gi|124256496 heat shock 70kDa protein 1-like [Homo sapiens] Length = 641 Score = 293 bits (749), Expect = 6e-79 Identities = 189/580 (32%), Positives = 312/580 (53%), Gaps = 27/580 (4%) Query: 4 VGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISNAKNT 63 +GIDLG V V + G +E IAN+ +R TP+ ++F R IG AAK+QV N +NT Sbjct: 9 IGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPQNT 68 Query: 64 VQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTAMLLS 123 V KR GR F+DP V+A+ + ++ G + V+Y E + F E++++M+L+ Sbjct: 69 VFDAKRLIGRKFNDPVVQADMKLWPFQVIN-EGGKPKVLVSYKGENKAFYPEEISSMVLT 127 Query: 124 KLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVALAYGI 183 KLKETAE+ L PV + V++VP ++ D++R++ DA IAGLN LR++NE TA A+AYG+ Sbjct: 128 KLKETAEAFLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGL 187 Query: 184 YKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVLVNH 243 K + R+V+ D+G + VS+ + G +V ATA DT LGG FD LV+H Sbjct: 188 DKGG-----QGERHVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVSH 242 Query: 244 FCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMNDVDVSGTMNR 303 F EEF +K+K DI RA+ RL CE+ K+ +S +++ L I+ +D ++ R Sbjct: 243 FVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLS-SSTQANLEIDSLYEGIDFYTSITR 301 Query: 304 GKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEKISKFF-GKEL 362 +F E+C DL P+ L K+ K I+ + +VGG+TRIP V+ + +F G++L Sbjct: 302 ARFEELCADLFRGTLEPVEKALRDAKMDKAKIHDIVLVGGSTRIPKVQRLLQDYFNGRDL 361 Query: 363 STTLNADEAVTRGCALQCAIL--SPAFKVREFSITDVVPYPISLRWNSPAEEGSSDCEVF 420 + ++N DEAV G A+Q AIL + KV++ + DV P + L G + Sbjct: 362 NKSINPDEAVAYGAAVQAAILMGDKSEKVQDLLLLDVAPLSLGLE-----TAGGVMTALI 416 Query: 421 SKNHAAPFSKV---LTFYRKEPFTLEAYYSSPQDLPYPDPAIAQFSVQKVTPQSDGSSSK 477 +N P + T+ +P L Y + + + + +F + + P G + Sbjct: 417 KRNSTIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFDLTGIPPAPRG-VPQ 475 Query: 478 VKVKVRVNVHGIFSVSSASLVEVHKSEENEEPMETDQN--AKEE-EKMQVDQEEPHVEE- 533 ++V ++ +GI +V++ + + N+ + D+ +KEE E+M +D E+ E+ Sbjct: 476 IEVTFDIDANGILNVTA---TDKSTGKVNKITITNDKGRLSKEEIERMVLDAEKYKAEDE 532 Query: 534 -QQQQTPAENKAESEEMETSQAGSKDKKMDQPPQAKKAKV 572 Q+++ A+N ES S + + ++ K K+ Sbjct: 533 VQREKIAAKNALESYAFNMKSVVSDEGLKGKISESDKNKI 572 Score = 44.3 bits (103), Expect = 5e-04 Identities = 28/99 (28%), Positives = 52/99 (52%), Gaps = 2/99 (2%) Query: 588 QIDREMLNLYIENEGKMIMQDKLEKERNDAKNAVEEYVYEMRDKLSGEYEK-FVSEDDRN 646 ++ +E + + + K +D++++E+ AKNA+E Y + M+ +S E K +SE D+N Sbjct: 511 RLSKEEIERMVLDAEKYKAEDEVQREKIAAKNALESYAFNMKSVVSDEGLKGKISESDKN 570 Query: 647 SFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKNLGQPI 685 K + +WL E + K + K EL+ + PI Sbjct: 571 KILDKCNELLSWL-EVNQLAEKDEFDHKRKELEQMCNPI 608 Score = 32.3 bits (72), Expect = 1.9 Identities = 22/100 (22%), Positives = 43/100 (43%), Gaps = 14/100 (14%) Query: 686 KIRFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAADMTKVEKSTNEAMEWM 745 K + ++ +R K+ + ++ Y + S + E + +D K+ NE + W Sbjct: 526 KYKAEDEVQREKIAAK--NALESYAFNMKSVVSDEGLKGKISESDKNKILDKCNELLSW- 582 Query: 746 NNKLNLQNKQSLTMDPVVKSKEIEAKIKELTSTCSPIISK 785 L ++ + + E + K KEL C+PII+K Sbjct: 583 -----------LEVNQLAEKDEFDHKRKELEQMCNPIITK 611 >gi|5729877 heat shock 70kDa protein 8 isoform 1 [Homo sapiens] Length = 646 Score = 288 bits (738), Expect = 1e-77 Identities = 199/623 (31%), Positives = 322/623 (51%), Gaps = 36/623 (5%) Query: 4 VGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISNAKNT 63 VGIDLG V V + G +E IAN+ +R TP+ ++F R IG AAK+QV N NT Sbjct: 7 VGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNT 66 Query: 64 VQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTAMLLS 123 V KR GR F D V+++ + + +V G ++V Y E ++F E+V++M+L+ Sbjct: 67 VFDAKRLIGRRFDDAVVQSDMKHWPFMVVN-DAGRPKVQVEYKGETKSFYPEEVSSMVLT 125 Query: 124 KLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVALAYGI 183 K+KE AE+ L K V + VV+VP ++ D++R++ DA IAGLN LR++NE TA A+AYG+ Sbjct: 126 KMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGL 185 Query: 184 YKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVLVNH 243 K+ RNV+ D+G + VS+ G +V +TA DT LGG FD +VNH Sbjct: 186 DKK-----VGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNH 240 Query: 244 FCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMNDVDVSGTMNR 303 F EF +K+K DI RA+ RL CE+ K+ +S +++ + I+ +D ++ R Sbjct: 241 FIAEFKRKHKKDISENKRAVRRLRTACERAKRTLS-SSTQASIEIDSLYEGIDFYTSITR 299 Query: 304 GKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEKISKFF-GKEL 362 +F E+ DL P+ L KL K I+ + +VGG+TRIP +++ + FF GKEL Sbjct: 300 ARFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKEL 359 Query: 363 STTLNADEAVTRGCALQCAILS--PAFKVREFSITDVVPYPISLRWNSPAEEGSSDCEVF 420 + ++N DEAV G A+Q AILS + V++ + DV P + + G + Sbjct: 360 NKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIE-----TAGGVMTVLI 414 Query: 421 SKNHAAPFSKVLTFYR---KEPFTLEAYYSSPQDLPYPDPAIAQFSVQKVTPQSDGSSSK 477 +N P + TF +P L Y + + + + +F + + P G + Sbjct: 415 KRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRG-VPQ 473 Query: 478 VKVKVRVNVHGIFSVSSASLVEVHKSEENEEPMETDQN--AKEEEKMQVDQEEPHV---E 532 ++V ++ +GI +VS+ V+ +EN+ + D+ +KE+ + V + E + E Sbjct: 474 IEVTFDIDANGILNVSA---VDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDE 530 Query: 533 EQQQQTPAENKAESEEMETSQAGSKDKKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDRE 592 +Q+ + ++N ES +K + K K+ L N+++ +D+ Sbjct: 531 KQRDKVSSKNSLESYAFNMKATVEDEKLQGKINDEDKQKI------LDKCNEIINWLDK- 583 Query: 593 MLNLYIENEGKMIMQDKLEKERN 615 N E E Q +LEK N Sbjct: 584 --NQTAEKEEFEHQQKELEKVCN 604 Score = 39.3 bits (90), Expect = 0.015 Identities = 22/110 (20%), Positives = 56/110 (50%), Gaps = 10/110 (9%) Query: 588 QIDREMLNLYIENEGKMIMQDKLEKERNDAKNAVEEYVYEMR-----DKLSGEYEKFVSE 642 ++ +E + ++ K +D+ ++++ +KN++E Y + M+ +KL G+ +++ Sbjct: 509 RLSKEDIERMVQEAEKYKAEDEKQRDKVSSKNSLESYAFNMKATVEDEKLQGK----IND 564 Query: 643 DDRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKNLGQPIKIRFQES 692 +D+ K + NWL + + K+ + + EL+ + PI + +S Sbjct: 565 EDKQKILDKCNEIINWL-DKNQTAEKEEFEHQQKELEKVCNPIITKLYQS 613 Score = 31.6 bits (70), Expect = 3.2 Identities = 25/118 (21%), Positives = 50/118 (42%), Gaps = 12/118 (10%) Query: 679 KNLGQPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAADMTKVEKST 738 K+ G+ KI + R E++ + +Q+ K + + + D+ ++ + Sbjct: 493 KSTGKENKITITNDKGRLSK-EDIERMVQEAEKYKAEDEKQRDKVSSKNSLESYAFNMKA 551 Query: 739 NEAMEWMNNKLNLQNKQS-----------LTMDPVVKSKEIEAKIKELTSTCSPIISK 785 E + K+N ++KQ L + + +E E + KEL C+PII+K Sbjct: 552 TVEDEKLQGKINDEDKQKILDKCNEIINWLDKNQTAEKEEFEHQQKELEKVCNPIITK 609 >gi|16507237 heat shock 70kDa protein 5 [Homo sapiens] Length = 654 Score = 284 bits (727), Expect = 2e-76 Identities = 194/603 (32%), Positives = 316/603 (52%), Gaps = 44/603 (7%) Query: 2 SVVGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISFGPKN-RSIGAAAKSQVISNA 60 +VVGIDLG V V + G +E IAN+ +R TP+ ++F P+ R IG AAK+Q+ SN Sbjct: 29 TVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNP 88 Query: 61 KNTVQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYME------EERNFTT 114 +NTV KR GR ++DP V+ + L + +V+ T Y++ + + F Sbjct: 89 ENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTK------PYIQVDIGGGQTKTFAP 142 Query: 115 EQVTAMLLSKLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNET 174 E+++AM+L+K+KETAE+ L K V VV+VP ++ DA+R++ DA IAGLN +R++NE Sbjct: 143 EEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEP 202 Query: 175 TAVALAYGIYKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGR 234 TA A+AYG+ K+ E +N++ D+G + VS+ + G +V+AT DT LGG Sbjct: 203 TAAAIAYGLDKR------EGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGE 256 Query: 235 KFDEVLVNHFCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMND 294 FD+ ++ HF + + KK D++ RA+ +L +E EK K+ +S+ + IE F Sbjct: 257 DFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQ-HQARIEIESFYEG 315 Query: 295 VDVSGTMNRGKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEKI 354 D S T+ R KF E+ DL P++ VLE + LKK DI + +VGG+TRIP +++ + Sbjct: 316 EDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLV 375 Query: 355 SKFF-GKELSTTLNADEAVTRGCALQCAILSPAFKVREFSITDVVPYPISLRWNSPAEEG 413 +FF GKE S +N DEAV G A+Q +LS + + DV P + + G Sbjct: 376 KEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVCPLTLGIE-----TVG 430 Query: 414 SSDCEVFSKNHAAPFSKVLTFYR---KEPFTLEAYYSSPQDLPYPDPAIAQFSVQKVTPQ 470 ++ +N P K F +P Y + L + + F + + P Sbjct: 431 GVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPA 490 Query: 471 SDGSSSKVKVKVRVNVHGIFSVSSASLVEVHKSEENEEPMETDQN---AKEEEKMQVDQE 527 G +++V ++V+GI V++ + +N+ + DQN +E E+M D E Sbjct: 491 PRG-VPQIEVTFEIDVNGILRVTAE---DKGTGNKNKITITNDQNRLTPEEIERMVNDAE 546 Query: 528 EPHVEEQQQQTPAENKAESEEMETS---QAGSKDKKMDQPPQAKKAKVKTSTVDLPIENQ 584 + E+++ + + + E E S Q G K+K K + T++ +E + Sbjct: 547 KFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKL-----GGKLSSEDKETMEKAVEEK 601 Query: 585 LLW 587 + W Sbjct: 602 IEW 604 Score = 47.4 bits (111), Expect = 6e-05 Identities = 32/113 (28%), Positives = 56/113 (49%), Gaps = 5/113 (4%) Query: 592 EMLNLYIENEGKMIMQDKLEKERNDAKNAVEEYVYEMRDKLSGEYEKF---VSEDDRNSF 648 E + + + K +DK KER D +N +E Y Y +++++ G+ EK +S +D+ + Sbjct: 536 EEIERMVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQI-GDKEKLGGKLSSEDKETM 594 Query: 649 TLKLEDTENWLYEDGEDQPKQVYVDKLAELKNLGQPIKIRFQESEERPKLFEE 701 +E+ WL E +D + + K EL+ + QPI + S P EE Sbjct: 595 EKAVEEKIEWL-ESHQDADIEDFKAKKKELEEIVQPIISKLYGSAGPPPTGEE 646 Score = 35.4 bits (80), Expect = 0.22 Identities = 30/118 (25%), Positives = 54/118 (45%), Gaps = 14/118 (11%) Query: 688 RFQESEERPKLFEELGKQIQQYM-KIISSFKNKEDQYDHLDAADMTKVEKSTNEAMEWMN 746 +F E +++ K + +++ Y + + +KE L + D +EK+ E +EW Sbjct: 547 KFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEEKIEW-- 604 Query: 747 NKLNLQNKQSLTMDPVVKSKEIEAKIKELTSTCSPIISKPKPKV-EPPKEEQKNAEQN 803 L++ Q ++ + +AK KEL PIISK PP E+ AE++ Sbjct: 605 ----LESHQDADIE------DFKAKKKELEEIVQPIISKLYGSAGPPPTGEEDTAEKD 652 >gi|13676857 heat shock 70kDa protein 2 [Homo sapiens] Length = 639 Score = 271 bits (692), Expect = 2e-72 Identities = 179/580 (30%), Positives = 298/580 (51%), Gaps = 25/580 (4%) Query: 4 VGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISNAKNT 63 +GIDLG V V + G +E IAN+ +R TP+ ++F R IG AAK+QV N NT Sbjct: 8 IGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNT 67 Query: 64 VQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTAMLLS 123 + KR GR F D V+++ + + +V G ++V Y E + F E++++M+L+ Sbjct: 68 IFDAKRLIGRKFEDATVQSDMKHWPFRVVS-EGGKPKVQVEYKGETKTFFPEEISSMVLT 126 Query: 124 KLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVALAYGI 183 K+KE AE+ L V V++VP ++ D++R++ DA I GLN LR++NE TA A+AYG+ Sbjct: 127 KMKEIAEAYLGGKVHSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAAAIAYGL 186 Query: 184 YKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVLVNH 243 K+ E +NV+ D+G + VS+ G +V +TA DT LGG FD +V+H Sbjct: 187 DKKGCAGGE---KNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVSH 243 Query: 244 FCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMNDVDVSGTMNR 303 EEF +K+K DI RA+ RL CE+ K+ +S +++ + I+ VD ++ R Sbjct: 244 LAEEFKRKHKKDIGPNKRAVRRLRTACERAKRTLS-SSTQASIEIDSLYEGVDFYTSITR 302 Query: 304 GKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEKISKFF-GKEL 362 +F E+ DL P+ L KL K I + +VGG+TRIP +++ + FF GKEL Sbjct: 303 ARFEELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGKEL 362 Query: 363 STTLNADEAVTRGCALQCAIL--SPAFKVREFSITDVVPYPISLRWNSPAEEGSSDCEVF 420 + ++N DEAV G A+Q AIL + V++ + DV P + + G + Sbjct: 363 NKSINPDEAVAYGAAVQAAILIGDKSENVQDLLLLDVTPLSLGIE-----TAGGVMTPLI 417 Query: 421 SKNHAAPFSKVLTFYR---KEPFTLEAYYSSPQDLPYPDPAIAQFSVQKVTPQSDGSSSK 477 +N P + TF + L Y + + + + +F + + P G + Sbjct: 418 KRNTTIPTKQTQTFTTYSDNQSSVLVQVYEGERAMTKDNNLLGKFDLTGIPPAPRG-VPQ 476 Query: 478 VKVKVRVNVHGIFSVSSASLVEVHKSEENEEPMETDQN--AKEEEKMQVDQEEPHVEEQQ 535 ++V ++ +GI +V++A + +EN+ + D+ +K++ V + E + E + Sbjct: 477 IEVTFDIDANGILNVTAA---DKSTGKENKITITNDKGRLSKDDIDRMVQEAERYKSEDE 533 Query: 536 ---QQTPAENKAESEEMETSQAGSKDKKMDQPPQAKKAKV 572 + A+N ES Q +K + + K K+ Sbjct: 534 ANRDRVAAKNALESYTYNIKQTVEDEKLRGKISEQDKNKI 573 Score = 44.3 bits (103), Expect = 5e-04 Identities = 25/99 (25%), Positives = 50/99 (50%), Gaps = 2/99 (2%) Query: 588 QIDREMLNLYIENEGKMIMQDKLEKERNDAKNAVEEYVYEMRDKLSGE-YEKFVSEDDRN 646 ++ ++ ++ ++ + +D+ ++R AKNA+E Y Y ++ + E +SE D+N Sbjct: 512 RLSKDDIDRMVQEAERYKSEDEANRDRVAAKNALESYTYNIKQTVEDEKLRGKISEQDKN 571 Query: 647 SFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKNLGQPI 685 K ++ NWL + + K Y K EL+ + PI Sbjct: 572 KILDKCQEVINWL-DRNQMAEKDEYEHKQKELERVCNPI 609 >gi|24234686 heat shock 70kDa protein 8 isoform 2 [Homo sapiens] Length = 493 Score = 270 bits (689), Expect = 5e-72 Identities = 161/434 (37%), Positives = 244/434 (56%), Gaps = 15/434 (3%) Query: 4 VGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISNAKNT 63 VGIDLG V V + G +E IAN+ +R TP+ ++F R IG AAK+QV N NT Sbjct: 7 VGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNT 66 Query: 64 VQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTAMLLS 123 V KR GR F D V+++ + + +V G ++V Y E ++F E+V++M+L+ Sbjct: 67 VFDAKRLIGRRFDDAVVQSDMKHWPFMVVN-DAGRPKVQVEYKGETKSFYPEEVSSMVLT 125 Query: 124 KLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVALAYGI 183 K+KE AE+ L K V + VV+VP ++ D++R++ DA IAGLN LR++NE TA A+AYG+ Sbjct: 126 KMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGL 185 Query: 184 YKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVLVNH 243 K+ RNV+ D+G + VS+ G +V +TA DT LGG FD +VNH Sbjct: 186 DKK-----VGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNH 240 Query: 244 FCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMNDVDVSGTMNR 303 F EF +K+K DI RA+ RL CE+ K+ +S +++ + I+ +D ++ R Sbjct: 241 FIAEFKRKHKKDISENKRAVRRLRTACERAKRTLS-SSTQASIEIDSLYEGIDFYTSITR 299 Query: 304 GKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEKISKFF-GKEL 362 +F E+ DL P+ L KL K I+ + +VGG+TRIP +++ + FF GKEL Sbjct: 300 ARFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKEL 359 Query: 363 STTLNADEAVTRGCALQCAILS--PAFKVREFSITDVVPYPISLRWNSPAEEGSSDCEVF 420 + ++N DEAV G A+Q AILS + V++ + DV P + + G + Sbjct: 360 NKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIE-----TAGGVMTVLI 414 Query: 421 SKNHAAPFSKVLTF 434 +N P + TF Sbjct: 415 KRNTTIPTKQTQTF 428 >gi|24234688 heat shock 70kDa protein 9 precursor [Homo sapiens] Length = 679 Score = 219 bits (558), Expect = 8e-57 Identities = 158/573 (27%), Positives = 277/573 (48%), Gaps = 39/573 (6%) Query: 2 SVVGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISF-GPKNRSIGAAAKSQVISNA 60 +VVGIDLG + VAV + + N R TP+ ++F R +G AK Q ++N Sbjct: 54 AVVGIDLGTTNSCVAVMEGKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQAVTNP 113 Query: 61 KNTVQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTAM 120 NT KR GR + DP V+ + N+ + IV+ G ++ + ++ Q+ A Sbjct: 114 NNTFYATKRLIGRRYDDPEVQKDIKNVPFKIVRASNGDAWVEA----HGKLYSPSQIGAF 169 Query: 121 LLSKLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVALA 180 +L K+KETAE+ L + V++VP ++ D++R++ DA QI+GLN LR++NE TA ALA Sbjct: 170 VLMKMKETAENYLGHTAKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAAALA 229 Query: 181 YGIYKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVL 240 YG+ K + + + D+G + +S+ +G +V +T DT LGG FD+ L Sbjct: 230 YGLDKSE-------DKVIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTFLGGEDFDQAL 282 Query: 241 VNHFCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANAS---DLPLSIECFMNDVDV 297 + H +EF ++ +D+ AL R+ + EK K +S++ +LP + Sbjct: 283 LRHIVKEFKRETGVDLTKDNMALQRVREAAEKAKCELSSSVQTDINLPYLTMDSSGPKHL 342 Query: 298 SGTMNRGKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEKISKF 357 + + R +F + DL+ R P + ++ ++ K DI V +VGG TR+P V++ + Sbjct: 343 NMKLTRAQFEGIVTDLIRRTIAPCQKAMQDAEVSKSDIGEVILVGGMTRMPKVQQTVQDL 402 Query: 358 FGKELSTTLNADEAVTRGCALQCAILSPAFKVREFSITDVVPYPISLRWNSPAEEGSSDC 417 FG+ S +N DEAV G A+Q +L A V + + DV P + + G Sbjct: 403 FGRAPSKAVNPDEAVAIGAAIQGGVL--AGDVTDVLLLDVTPLSLGIE-----TLGGVFT 455 Query: 418 EVFSKNHAAPFSKVLTFYRKEPFTLEA---YYSSPQDLPYPDPAIAQFSVQKVTPQSDGS 474 ++ ++N P K F + +++ + + QF++ + P G Sbjct: 456 KLINRNTTIPTKKSQVFSTAADGQTQVEIKVCQGEREMAGDNKLLGQFTLIGIPPAPRG- 514 Query: 475 SSKVKVKVRVNVHGIFSVSSASLVEVHKSEENEEPMETDQN---AKEEEKMQVDQEEPHV 531 +++V ++ +GI VS+ K E+ + + +K++ + V E + Sbjct: 515 VPQIEVTFDIDANGIVHVSAKD-----KGTGREQQIVIQSSGGLSKDDIENMVKNAEKYA 569 Query: 532 EE---QQQQTPAENKAES--EEMETSQAGSKDK 559 EE ++++ A N AE + ET KD+ Sbjct: 570 EEDRRKKERVEAVNMAEGIIHDTETKMEEFKDQ 602 >gi|82880658 heat shock 70kDa protein 14 isoform 1 [Homo sapiens] Length = 509 Score = 191 bits (485), Expect = 2e-48 Identities = 123/391 (31%), Positives = 200/391 (51%), Gaps = 21/391 (5%) Query: 1 MSVVGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISNA 60 M+ +G+ LG S VAV + G +AN+ DR TPA +++ +G AAK I N Sbjct: 1 MAAIGVHLGCTSACVAVYKDGRAGVVANDAGDRVTPAVVAYSENEEIVGLAAKQSRIRNI 60 Query: 61 KNTVQGFKRFHGRAFSDPFVE---AEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQV 117 NTV K+ GR+ SDP + AE L + G ++ EE + E V Sbjct: 61 SNTVMKVKQILGRSSSDPQAQKYIAESKCLVIE----KNGKLRYEIDTGEETKFVNPEDV 116 Query: 118 TAMLLSKLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAV 177 ++ SK+KETA SVL D V++VP + + ++ ++ +A + AG N LRL++E +A Sbjct: 117 ARLIFSKMKETAHSVLGSDANDVVITVPFDFGEKQKNALGEAARAAGFNVLRLIHEPSAA 176 Query: 178 ALAYGIYKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGRKFD 237 LAYGI QD P + N++ +G ++ +SV N G +VL+T D +GG F Sbjct: 177 LLAYGI-GQDSPTGKS---NILVFKLGGTSLSLSVMEVNSGIYRVLSTNTDDNIGGAHFT 232 Query: 238 EVLVNHFCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMNDV-- 295 E L + EF + +K D++ RA+++L+ E K +S S CF++ + Sbjct: 233 ETLAQYLASEFQRSFKHDVRGNARAMMKLTNSAEVAKHSLSTLG-----SANCFLDSLYE 287 Query: 296 --DVSGTMNRGKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEK 353 D ++R +F +C+ L + +R +L+Q +DI V + GG++RIP +++ Sbjct: 288 GQDFDCNVSRARFELLCSPLFNKCIEAIRGLLDQNGFTADDINKVVLCGGSSRIPKLQQL 347 Query: 354 ISKFF-GKELSTTLNADEAVTRGCALQCAIL 383 I F EL ++ DE + G A++ IL Sbjct: 348 IKDLFPAVELLNSIPPDEVIPIGAAIEAGIL 378 >gi|48928056 heat shock protein 70kDa family member 13 precursor [Homo sapiens] Length = 471 Score = 163 bits (412), Expect = 7e-40 Identities = 124/424 (29%), Positives = 204/424 (48%), Gaps = 54/424 (12%) Query: 3 VVGIDLGFQSCYVAV--ARAGGIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISNA 60 V+GIDLG C V V G ++ I +E P+ +SF + +G + SN Sbjct: 33 VIGIDLGTTYCSVGVFFPGTGKVKVIPDENGHISIPSMVSFTDNDVYVGYESVELADSNP 92 Query: 61 KNTVQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTAM 120 +NT+ KRF G+ F+ +EAE + ++ G+ VT E + E V + Sbjct: 93 QNTIYDAKRFIGKIFTAEELEAEIGRYPFKVLN-KNGMVEFSVT-SNETITVSPEYVGSR 150 Query: 121 LLSKLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVALA 180 LL KLKE AE+ L PV + V+SVP + +R S ++A +AGL LR++NE TA A+A Sbjct: 151 LLLKLKEMAEAYLGMPVANAVISVPAEFDLKQRNSTIEAANLAGLKILRVINEPTAAAMA 210 Query: 181 YGIYKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVL 240 YG++K D+ +V+ +D+G VS+ G A + + LGG+ F++ L Sbjct: 211 YGLHKADV-------FHVLVIDLGGGTLDVSLLNKQGGMFLTRAMSGNNKLGGQDFNQRL 263 Query: 241 VNHFCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANAS------------------ 282 + + ++ + Y + S+ + RL Q E +K ++ + S Sbjct: 264 LQYLYKQIYQTYGF-VPSRKEEIHRLRQAVEMVKLNLTLHQSAQLSVLLTVEEQDRKEPH 322 Query: 283 ----DLPLSIECFMNDVDVSGTMNRG-------------------KFLEMCN-DLLARVE 318 +LP +D V+ RG K + N DL ++ Sbjct: 323 SSDTELPKDKLSSADDHRVNSGFGRGLSDKKSGESQVLFETEISRKLFDTLNEDLFQKIL 382 Query: 319 PPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEKISKFFGKELSTTLNADEAVTRGCAL 378 P++ VL++ L+K +I V +VGG+TRIP +++ I +FFGK+ +T+++ D AV G A+ Sbjct: 383 VPIQQVLKEGHLEKTEIDEVVLVGGSTRIPRIRQVIQEFFGKDPNTSVDPDLAVVTGVAI 442 Query: 379 QCAI 382 Q I Sbjct: 443 QAGI 446 >gi|221219020 NYD-SP11 protein [Homo sapiens] Length = 2873 Score = 59.7 bits (143), Expect = 1e-08 Identities = 70/292 (23%), Positives = 129/292 (44%), Gaps = 40/292 (13%) Query: 492 VSSASLVEVHKSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQ-------QQQTPAENKA 544 +SS S + +K EE E EE++ QV +E+ H++E+ +++ AE K Sbjct: 1529 LSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKR 1588 Query: 545 ESEEMETSQAGSKDKKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKM 604 EE + +Q K + ++ ++ K+ + V + Q DREM + EGK Sbjct: 1589 AQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKIT-------QDDREM----AQAEGKF 1637 Query: 605 IMQDKLEKERNDAKNAVEEYVYEMRDKLSGEYEKFVSEDDRNSFT-LKLEDTENWLYEDG 663 +++ +R + + E + + R KL+ ++EK E+++ + KL + +N L + Sbjct: 1638 AQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKV 1697 Query: 664 EDQPKQVYVDKLAELKNLGQPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQY 723 E+ P++ +NL K QE EE EEL S+K +E Sbjct: 1698 EELPQRE--------QNLDWQEKELAQELEELEWDMEEL------------SWKEEELNQ 1737 Query: 724 DHLDAADMTKVEKSTNEAMEWMNNKLN-LQNKQSLTMDPVVKSKEIEAKIKE 774 + + K EA+ W KL+ + K + + +++ KE A+ KE Sbjct: 1738 EEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKE 1789 Score = 47.4 bits (111), Expect = 6e-05 Identities = 33/146 (22%), Positives = 70/146 (47%), Gaps = 3/146 (2%) Query: 499 EVHKSEENE---EPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAG 555 E H SEE E + +E ++ EE+ + ++EE EE+ ++ E K E E E Sbjct: 2223 EEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEK 2282 Query: 556 SKDKKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERN 615 +++K + + KK +V+ + +++ + + E L+ E E +++++++E+ Sbjct: 2283 EEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKE 2342 Query: 616 DAKNAVEEYVYEMRDKLSGEYEKFVS 641 K + + E R K E+ +S Sbjct: 2343 ILKKEKQFKLQEQRRKSLRGRERVLS 2368 Score = 44.3 bits (103), Expect = 5e-04 Identities = 36/154 (23%), Positives = 77/154 (50%), Gaps = 8/154 (5%) Query: 494 SASLVEVHKSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQ 553 S+ + EV E E ME+ + E+++ +EE EE++++ E + E EE + + Sbjct: 2214 SSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEE 2273 Query: 554 AGSKDKKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKE 613 G ++K++++ + KK K K + E + +++ E+++ E E + + ++ E+E Sbjct: 2274 EG-EEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMS---EEETESLSDEEEEEE 2329 Query: 614 RNDAKNAVEEYVYEMRDKLSGEYEKFVSEDDRNS 647 ++EE V ++ L E + + E R S Sbjct: 2330 ----SCSLEEEVDREKEILKKEKQFKLQEQRRKS 2359 Score = 35.4 bits (80), Expect = 0.22 Identities = 59/293 (20%), Positives = 128/293 (43%), Gaps = 29/293 (9%) Query: 499 EVHKSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKD 558 E K E EE + + EE+ ++ QEE + Q+++ A++K + E E ++ Sbjct: 1745 EKKKLAEEEEALAWQREKLSEEETKLAQEE-ELLIQEKEKLAQHKEKMPEEEERLGRKRE 1803 Query: 559 KKMDQPPQ--AKKAKVKTSTVDLPIENQLLWQ---IDREMLNLYIENEGKMIMQDKL--- 610 + +++ + K+ + S +L +L+Q + +E NL E E ++ L Sbjct: 1804 QLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYN 1863 Query: 611 -------EKERNDAKNAV---EEYVYEMRDKLSGEYEKFVSEDDRNSFT-LKLEDTENWL 659 +K+ KN + + + ++ +KL+ E E + + ++ + T KL E+ L Sbjct: 1864 KERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSL 1923 Query: 660 YEDGEDQPKQVYVDKLAELKNLGQ---PIKIRFQESEERPKLFEELGKQIQQYMKIISSF 716 + E ++ KLA K + Q ++ ++E L E+ + ++ M+++ Sbjct: 1924 AKKQEKLAQEKM--KLALEKAMVQGKKRLRGELDIAKEEKALNLEMKRLAEEKMRLVEG- 1980 Query: 717 KNKEDQYDHLDAADMTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIE 769 ++ + + ++ K T E KL+L+ K L D ++ +E E Sbjct: 1981 ---KETLSKGETPETSRQRKMTQVEQELFERKLSLEEKILLHEDRILAMEESE 2030 >gi|239745153 PREDICTED: similar to Putative golgin subfamily A member 6-like protein 6 [Homo sapiens] Length = 655 Score = 59.7 bits (143), Expect = 1e-08 Identities = 52/275 (18%), Positives = 126/275 (45%), Gaps = 16/275 (5%) Query: 502 KSEENEEPM-ETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKK 560 K +E EE M E + +E+E+ QEE E++++ E+K +E + + K ++ Sbjct: 305 KIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIRE 364 Query: 561 MDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAKNA 620 ++ ++ K++ + + + +W+ + ++ + + KM Q+K +E+++ Sbjct: 365 QEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIRE 424 Query: 621 VEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKN 680 EE ++ +K+ E E+ + + + KL + E + E+ E K+ E + Sbjct: 425 QEEEMWRQEEKIR-ELEEMMQDQEE-----KLREVEEKMQEEEE---------KMQEQEE 469 Query: 681 LGQPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAADMTKVEKSTNE 740 Q + + QE EE+ E+L KQ ++ + +E++ + + EK + Sbjct: 470 KIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQ 529 Query: 741 AMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKEL 775 + ++ L ++ + V+ +E+E ++ +L Sbjct: 530 EEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKL 564 >gi|239745127 PREDICTED: similar to Putative golgin subfamily A member 6-like protein 6 [Homo sapiens] Length = 655 Score = 59.7 bits (143), Expect = 1e-08 Identities = 52/275 (18%), Positives = 126/275 (45%), Gaps = 16/275 (5%) Query: 502 KSEENEEPM-ETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKK 560 K +E EE M E + +E+E+ QEE E++++ E+K +E + + K ++ Sbjct: 305 KIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIRE 364 Query: 561 MDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAKNA 620 ++ ++ K++ + + + +W+ + ++ + + KM Q+K +E+++ Sbjct: 365 QEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIRE 424 Query: 621 VEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKN 680 EE ++ +K+ E E+ + + + KL + E + E+ E K+ E + Sbjct: 425 QEEEMWRQEEKIR-ELEEMMQDQEE-----KLREVEEKMQEEEE---------KMQEQEE 469 Query: 681 LGQPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAADMTKVEKSTNE 740 Q + + QE EE+ E+L KQ ++ + +E++ + + EK + Sbjct: 470 KIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQ 529 Query: 741 AMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKEL 775 + ++ L ++ + V+ +E+E ++ +L Sbjct: 530 EEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKL 564 >gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 828 Score = 59.3 bits (142), Expect = 1e-08 Identities = 47/195 (24%), Positives = 90/195 (46%), Gaps = 9/195 (4%) Query: 499 EVHKSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKD 558 E K + EE M ++ +E+EK DQEE EE++ + + E EEM Q K Sbjct: 525 EQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQE-EKM 583 Query: 559 KKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAK 618 ++ ++ + ++ K+ + + + +W+ + +M E E KM Q+++ E+ + Sbjct: 584 QEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQ--EEEDKMQEQEEMMWEQEEKM 641 Query: 619 NAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLAEL 678 EE ++E +K+ + EK +++ K++ E + E E Q + E Sbjct: 642 QEQEEKMWEQEEKMREQEEKMREQEE------KMQGQEEKMREQEEKMQGQEEKMREQEE 695 Query: 679 KNLGQPIKIRFQESE 693 K GQ K+ QE + Sbjct: 696 KMRGQEEKMWGQEEK 710 Score = 51.6 bits (122), Expect = 3e-06 Identities = 64/330 (19%), Positives = 147/330 (44%), Gaps = 33/330 (10%) Query: 502 KSEENEEPM--------ETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQ 553 K E EE M E ++ +E+EK +Q++ +E+Q Q E E EE Q Sbjct: 270 KMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQ 329 Query: 554 AGSKDKKMDQPPQAKKAKVKTSTVDLPIENQLLWQID----------REMLNLYIENEGK 603 K + ++ ++ +++ + + + +W+ D RE ++ E E K Sbjct: 330 E-EKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMW-EQEEK 387 Query: 604 MIMQDKLEKERNDAKNAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTEN--WLYE 661 M ++++ +ER EE + E +K+ + E ++++ +L + + W E Sbjct: 388 MQEEERI-REREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQE 446 Query: 662 DGEDQPKQVY--VDKLAELKNL-GQPIKIRFQES--EERPKLFEELGKQIQQYMKIISSF 716 ++Q ++++ +K+ + + + GQ K+ QE E+ +++E+ K Q K+ Sbjct: 447 KMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQE 506 Query: 717 KNKEDQYDHL-DAADMTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKEL 775 + +Q + L + + + +K + E M + Q ++ T D K +E E +++E Sbjct: 507 ERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMRE-EERMRER 565 Query: 776 TSTC---SPIISKPKPKVEPPKEEQKNAEQ 802 ++ + + K++ +E+ + E+ Sbjct: 566 EKKMREEEEMMREQEEKMQEQEEKMREQEE 595 Score = 48.9 bits (115), Expect = 2e-05 Identities = 65/327 (19%), Positives = 145/327 (44%), Gaps = 24/327 (7%) Query: 504 EENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKKMDQ 563 E++E E ++ +E+EKM +E+ EE+ ++ + + E E M + + ++ + Sbjct: 363 EQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENM 422 Query: 564 PPQAKKAKVKTSTVDLPIENQLLWQIDR--EMLNLYIENEGKMIMQDKL---EKE--RND 616 Q +K + LP + + LW+ ++ E E E K+ Q+++ EK+ R + Sbjct: 423 WEQEEK---EWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQE 479 Query: 617 AKNAVEEYVYEMRDKLSGEYEKFVSEDDRN-SFTLKLEDTENWLYE-----DGEDQPKQV 670 E+ ++E +K+ + +K +++R +L + E + E E++ ++ Sbjct: 480 KMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREE 539 Query: 671 YVDKLAELKNLGQPIKI----RFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHL 726 + E K Q K+ R +E E++ + EE+ ++ ++ M+ ++++ Sbjct: 540 KKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWE 599 Query: 727 DAADMTKVEKSTNEAMEWM---NNKLNLQNKQSLTMDPVVKSKEIEAKIKELTSTCSPII 783 M + E+ E E M + +Q ++ + + K +E E K+ E Sbjct: 600 QEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQE 659 Query: 784 SKPKPKVEPPK-EEQKNAEQNGPVDGQ 809 K + + E + +E+K EQ + GQ Sbjct: 660 EKMREQEEKMQGQEEKMREQEEKMQGQ 686 Score = 44.3 bits (103), Expect = 5e-04 Identities = 61/325 (18%), Positives = 139/325 (42%), Gaps = 22/325 (6%) Query: 497 LVEVHKSEENEEPMETDQNAKEEEKMQVDQEEP--HVEEQQQQTPAENKAESEEMETSQA 554 L +V + EE ++ +E+EK QEE EE+ ++ + + + E+M + Sbjct: 224 LPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEK 283 Query: 555 GSKDKKMDQPPQAK----KAKVKTSTVDLPIENQLLWQID---REMLNLYIENEGKMIMQ 607 ++++ + Q K + K++ + + + +W+ + RE E ++ Q Sbjct: 284 RLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQ 343 Query: 608 DKLEKERNDAKNAVEEYVYEMRDKL------SGEYEKFVSEDDRNSFTLKLEDTENWLYE 661 +K +E+ EE ++E ++L E EK ++++ ++ + E + E Sbjct: 344 EKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMRE 403 Query: 662 DGEDQPKQVYVDKLAELKNLGQPIKIRFQES---EERPKLFEELGKQIQQYMKIISSFKN 718 + E +Q + E +N+ + + +Q+ E++ KL+E+ K +Q KI + Sbjct: 404 EEETMREQEEKMQKQE-ENMWEQEEKEWQQQRLPEQKEKLWEQ-EKMQEQEEKIWEQEEK 461 Query: 719 KEDQYDHL-DAADMTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKELTS 777 DQ + M + EK + + + +++++ D + E + +++E Sbjct: 462 IRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEE 521 Query: 778 TCSPIISKPKPKVEPPKEEQKNAEQ 802 K + E +EE+K EQ Sbjct: 522 RMRE-QKKMWQQEEKMREEKKTQEQ 545 Score = 43.5 bits (101), Expect = 8e-04 Identities = 27/132 (20%), Positives = 65/132 (49%), Gaps = 1/132 (0%) Query: 502 KSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKKM 561 + EE ++ E ++ E+E+ +QEE E++++ E K +E + K ++ Sbjct: 620 EQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQ 679 Query: 562 DQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAKNAV 621 ++ Q ++ K++ + + + +W + +M + G+ M++K E+ R D K + Sbjct: 680 EEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIR-DQKEKM 738 Query: 622 EEYVYEMRDKLS 633 +E + E ++ S Sbjct: 739 QERLPEHEERCS 750 >gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 899 Score = 58.2 bits (139), Expect = 3e-08 Identities = 60/290 (20%), Positives = 131/290 (45%), Gaps = 20/290 (6%) Query: 499 EVHKSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKD 558 E K E E M ++ +E+EK DQEE ++E+++ E K EE + K Sbjct: 415 EQEKMWEQVEKMREEKKMQEQEKKTRDQEE-KMQEEERIREREKKMREEEETMREQEEKM 473 Query: 559 KKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDR--EMLNLYIENEGKMIMQDKL---EKE 613 +K ++ ++ K + LP + + LW+ ++ E E E K+ Q+++ EK+ Sbjct: 474 QKQEENMWEQEEK-EWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKK 532 Query: 614 --RNDAKNAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYED--GEDQPKQ 669 R + E+ ++E +K+ + +K +++R + ++ + W E+ E++ + Sbjct: 533 MWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMR 592 Query: 670 VYVDKLAELKNLGQPIKIRFQESEER-----PKLFEELGKQIQQYMKIISSFKNKEDQYD 724 K+ E + + + + + QE EE+ K++E+ K +Q K+ + +Q + Sbjct: 593 EREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEE 652 Query: 725 HLDAADMTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKE 774 + +K W + K+ Q K + + + +++E K +E Sbjct: 653 KMWEQQRLPEQKE----KLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQE 698 Score = 52.0 bits (123), Expect = 2e-06 Identities = 55/235 (23%), Positives = 106/235 (45%), Gaps = 25/235 (10%) Query: 502 KSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKKM 561 K E E E ++ +EEE+M +QEE E++++ E K +E + + K + Sbjct: 584 KMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQ 643 Query: 562 DQPPQAKKAKVKTSTVDLPIENQLLWQIDR-EMLNLYIENEGKMIMQDKLEKERN----- 615 ++ ++ K+ LP + + LW+ ++ + E E K+ Q+K+EK+ Sbjct: 644 EEKMWEQEEKM-WEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKK 702 Query: 616 --DAKNAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVD 673 D + EE R+K E E+ + E + K+++ E + E E+ +Q Sbjct: 703 TWDQEKMREEESMREREKKMREEEEMMREQEE-----KMQEQEEKMQEQEEEMWEQ---- 753 Query: 674 KLAELKNLGQPIKIRFQE--SEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHL 726 E K Q K+ Q+ E++ KL+E +++Q+ KI + DQ + + Sbjct: 754 ---EEKMWEQEEKMWEQQRLPEQKEKLWEH--EKMQEQEKIWEQEEKMRDQEEKM 803 Score = 48.9 bits (115), Expect = 2e-05 Identities = 51/223 (22%), Positives = 98/223 (43%), Gaps = 28/223 (12%) Query: 497 LVEVHKSEENEEPMETDQNAKEEEKMQV----------DQEEPHVEEQQQQTPAENKAES 546 L E K +E E+ E ++ E+EKM+ DQE+ EE ++ + + E Sbjct: 667 LWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEE 726 Query: 547 E---EMETSQAGSKDKKMDQPPQAKKAKVKTSTVD--------LPIENQLLWQIDREMLN 595 E E E ++K +Q + + + K + LP + + LW+ ++ Sbjct: 727 EMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQ 786 Query: 596 LYI-ENEGKMIMQDKLEKERNDAKNAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLED 654 I E E KM Q++ + + + EE + +K+ G+ EK ++++ + ++ Sbjct: 787 EKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEK----MWGQE 842 Query: 655 TENWLYEDGEDQPKQVYVDKLAEL--KNLGQPIKIRFQESEER 695 + W E+ ++ Q +K+ E K GQ K+R QE + R Sbjct: 843 EKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMR 885 Score = 47.4 bits (111), Expect = 6e-05 Identities = 54/300 (18%), Positives = 137/300 (45%), Gaps = 16/300 (5%) Query: 505 ENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKKMDQP 564 E +E E ++ +E+E+ +QEE E++++ E + +E + + K + ++ Sbjct: 339 EQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEER 398 Query: 565 PQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAKNAVEEY 624 + +++ + + ++ Q+++ + E KM Q+K +++ + K EE Sbjct: 399 MWEQDERLREKEERMREQEKMWEQVEK------MREEKKMQEQEKKTRDQEE-KMQEEER 451 Query: 625 VYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQV--YVDKLAELKNLG 682 + E K+ E E ++++ ++ ++ W E+ E Q +++ +KL E + + Sbjct: 452 IREREKKMREEEETMREQEEK----MQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKM- 506 Query: 683 QPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAADMTKVEKSTNEAM 742 Q + + E EE+ + EE+ Q ++ M + +EDQ + M E+ + Sbjct: 507 QEQEEKIWEQEEKIRDQEEMWGQ-EKKMWRQEKMREQEDQMWEQE-EKMRDQEQKMWDQE 564 Query: 743 EWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKELTSTCSPIISKPKPKVEPPKEEQKNAEQ 802 E M K Q K++ + ++ +E + ++ ++ + + K++ +E+ + E+ Sbjct: 565 ERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEE 624 Score = 47.4 bits (111), Expect = 6e-05 Identities = 52/284 (18%), Positives = 128/284 (45%), Gaps = 17/284 (5%) Query: 499 EVHKSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKD 558 E E+ E+ E ++ +E+E+ QEE E+++Q E K +E + +D Sbjct: 347 EEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQE---ERMWEQD 403 Query: 559 KKMDQPPQAKKAKVKT-STVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDA 617 +++ + + + + K V+ E + + + +++ + E KM ++++ +ER Sbjct: 404 ERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTR----DQEEKMQEEERI-REREKK 458 Query: 618 KNAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTEN--WLYEDGEDQPKQVY--VD 673 EE + E +K+ + E ++++ +L + + W E ++Q ++++ + Sbjct: 459 MREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEE 518 Query: 674 KLAELKNL-GQPIKIRFQES--EERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAAD 730 K+ + + + GQ K+ QE E+ +++E+ K Q K+ + E + + Sbjct: 519 KIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKT 578 Query: 731 MTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKE 774 + EK E + ++ ++ + + K +E E K++E Sbjct: 579 WDQEEKMREEE-RMREREKKMREEEEMMREQEEKMQEQEEKMQE 621 Score = 42.0 bits (97), Expect = 0.002 Identities = 60/319 (18%), Positives = 141/319 (44%), Gaps = 41/319 (12%) Query: 464 VQKVTPQSDGSSSKVKVKVRVNVHGIFSVSSASLVEVHKSEENEEPMETDQNAKEEEKMQ 523 +Q+ P ++ S++++ V+ + + L +V + EE ++ +E+EK Sbjct: 230 LQEKLPLAESEKSEIQLNVK-ELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKI 288 Query: 524 VDQEEP--HVEEQQQQTPAENKAESEEMETSQAGSKDKKMDQPPQAKKAK----VKTSTV 577 QEE EE+ ++ + + + E+M + ++++ + Q K+ + ++ Sbjct: 289 RKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEE 348 Query: 578 DLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAKNAVEEYVYEMRDKLSGEYE 637 + + + +W+ + +M E E KM Q++ E+ E+ + E K+ + E Sbjct: 349 QMQEQEEKMWEQEEKMR----EQEEKMWRQEERLWEQ-------EKQMREQEQKMRDQEE 397 Query: 638 KFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKNLGQPIKIRFQESEERPK 697 + +D+R L + E + E + V+K+ E K + + K + ++ EE+ + Sbjct: 398 RMWEQDER------LREKEERM---REQEKMWEQVEKMREEKKMQEQEK-KTRDQEEKMQ 447 Query: 698 LFEELGKQIQQYMKIISSFKNKEDQYDHLDAADMTKVEKS--TNEAMEWMNNKLNLQNKQ 755 E + ++ ++ + + + +E++ M K E++ E EW +L Q ++ Sbjct: 448 EEERIREREKKMREEEETMREQEEK--------MQKQEENMWEQEEKEWQQQRLPEQKEK 499 Query: 756 SLTMDPVVKSKEIEAKIKE 774 + K +E E KI E Sbjct: 500 LWEQE---KMQEQEEKIWE 515 >gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] Length = 793 Score = 55.5 bits (132), Expect = 2e-07 Identities = 54/295 (18%), Positives = 128/295 (43%), Gaps = 16/295 (5%) Query: 491 SVSSASLVEVHKSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEME 550 +++ ASL + +N+ ++ ++EEK + QE +EE + T + K + + E Sbjct: 124 TITDASLSLPSRRMQNDTA--ENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAE 181 Query: 551 TSQAGSKDKKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKL 610 ++ K+K+ ++ + K+ + + V++ +E + + E + + ++N + K Sbjct: 182 ENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTT-ESQEETVVMSLKNGQISSEEPKQ 240 Query: 611 EKERNDAKNAVEEY-VYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQ 669 E+ER + + + E DK E E+ E + +K E + E + ++ Sbjct: 241 EEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERE-RIKAEQDKKIADERARIEAEE 299 Query: 670 VYVDKLAELKNLGQPIKIRFQE---SEERPKLFEELGKQIQQYMKIISSFKN-------- 718 + E + + ++R +E +EER ++ EE + ++ +I K Sbjct: 300 KAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRI 359 Query: 719 KEDQYDHLDAADMTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIK 773 KE++ + + E+ +E L+ K+ + +K +++E KI+ Sbjct: 360 KEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIE 414 Score = 32.7 bits (73), Expect = 1.4 Identities = 56/317 (17%), Positives = 121/317 (38%), Gaps = 70/317 (22%) Query: 502 KSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKKM 561 + ++ + +E ++A +E K++ ++ E +E + E KA+ ++++T+ + ++ Sbjct: 384 EEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVN---EKKAQEDKLQTAVLKKQGEEK 440 Query: 562 DQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAKNAV 621 QAK+ K++ E I +K++K++ Sbjct: 441 GTKVQAKREKLQEDKPTFKKEE---------------------IKDEKIKKDKEP----- 474 Query: 622 EEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKNL 681 +E V D+ G E V + T KL+ TEN Sbjct: 475 KEEVKSFMDRKKGFTE--VKSQNGEFMTHKLKHTEN-------------------TFSRP 513 Query: 682 GQPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAADMTKVEKSTNEA 741 G + +E+E P++ E GK++++ + + ++ + K+++ EA Sbjct: 514 GGRASVDTKEAEGAPQV--EAGKRLEELRR----------RRGETESEEFEKLKQKQQEA 561 Query: 742 ---MEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKELTSTCSPIISKPKPKVEPPKEEQK 798 +E + K + K + K +E + K++E + K ++E + E Sbjct: 562 ALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEK-----RRLKEEIERRRAEAA 616 Query: 799 NAEQNGPVDGQGDNPGP 815 Q P DG D+ P Sbjct: 617 EKRQKMPEDGLSDDKKP 633 >gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 668 Score = 55.1 bits (131), Expect = 3e-07 Identities = 47/236 (19%), Positives = 111/236 (47%), Gaps = 27/236 (11%) Query: 499 EVHKSEENEEPMETDQNAKEEEKMQVDQEEPHVEE-----QQQQTPAENKAESEEMETSQ 553 E K +E EE ++ +E+E++ +E+ H +E +++ E K +E + + Sbjct: 454 EEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIRE 513 Query: 554 AGSKDKKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKE 613 K + ++ + ++ K++ + + +++ + + +M E E KM Q+K+ ++ Sbjct: 514 QEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKM----GEQEEKMQEQEKMRRQ 569 Query: 614 RNDAKNAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVD 673 + EE + E ++K+ + EK +++ K+ + E + E E +Q + Sbjct: 570 EEKIREQ-EEKIREQKEKIREQEEKIWEQEE------KIREQEEMMQEQEEKMWEQ--EE 620 Query: 674 KLAELKNLGQPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAA 729 K+ E + + QE EE+ + EE K +Q +++ + ++ +HL+AA Sbjct: 621 KMCEQEE-------KMQEQEEKMRRQEE--KMWEQEVRLRQQEEKMQEHQEHLEAA 667 Score = 52.8 bits (125), Expect = 1e-06 Identities = 63/287 (21%), Positives = 130/287 (45%), Gaps = 26/287 (9%) Query: 502 KSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKKM 561 K E E+ E ++ +EEEK++ +QE+ +E + E E EE Q +KKM Sbjct: 385 KMHEQEKIREQEEKRQEEEKIR-EQEKRQEQEAKMWRQEEKIREQEEKIREQ----EKKM 439 Query: 562 DQPPQAKKAKVKTSTVDLPIENQLLWQID---REMLNLYIENEGKMIMQDKLEKE----- 613 + + + K + E + +W+ + RE ++ + E KM Q+K+ K+ Sbjct: 440 WRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKE-KMHEQEKIRKQEEKVW 498 Query: 614 -RNDAKNAVEEYVYEMRDKLSGEYEKFVSEDDR-NSFTLKLEDTENWLYEDGEDQPKQVY 671 + + + EE + E +K+ + EK ++++ K+ + E + E E +Q Sbjct: 499 RQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQ-- 556 Query: 672 VDKLAELKNL-GQPIKIRFQES---EERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLD 727 +K+ E + + Q KIR QE E++ K+ E+ K +Q KI + +E+ + Sbjct: 557 EEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKI----REQEEMMQEQE 612 Query: 728 AADMTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKE 774 + EK + + + ++ ++ + V+ ++ E K++E Sbjct: 613 EKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 659 Score = 51.2 bits (121), Expect = 4e-06 Identities = 66/345 (19%), Positives = 142/345 (41%), Gaps = 32/345 (9%) Query: 504 EENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKKMDQ 563 E E+ E ++ +E+E+ +QEE +++ E K +E + K +++++ Sbjct: 311 EWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEE 370 Query: 564 PPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYI-------ENEGKMIMQDKLEKERND 616 K+ K++ + + ++ Q ++ I E E KM Q++ +E+ + Sbjct: 371 MMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEE 430 Query: 617 AKNAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLA 676 E+ ++ +K+ E EK E+ R E E W E+ + ++++ K Sbjct: 431 KIREQEKKMWRQEEKIH-EQEKIREEEKRQ------EQEEMWRQEEKIREQEEIWRQK-- 481 Query: 677 ELKNLGQPIKIRFQESE---ERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAADMTK 733 + + + KIR QE + + K+ ++ K +Q K+ + +Q + + + Sbjct: 482 --EKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKI-----RE 534 Query: 734 VEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKELTSTCSPIISKPKPKVEPP 793 E+ E E M + +Q M K + E KI+E I + K K+ Sbjct: 535 QEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEK----IREQKEKIR-- 588 Query: 794 KEEQKNAEQNGPVDGQGDNPGPQAAEQGTDTAVPSDSDKKLPEMD 838 ++E+K EQ + Q + Q + + ++K+ E + Sbjct: 589 EQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQE 633 Score = 45.1 bits (105), Expect = 3e-04 Identities = 52/242 (21%), Positives = 102/242 (42%), Gaps = 28/242 (11%) Query: 499 EVHKSEENEEPMETDQNAKEEEKMQ------VDQEEPHVEEQQQQTPAENK--------- 543 E K E EE + ++ +E+EK Q QEE E++++ E K Sbjct: 388 EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIH 447 Query: 544 ------AESEEMETSQAGSKDKKMDQPPQAKKAKVKTSTVD-LPIENQLLWQIDREMLN- 595 E + E + +++K+ + + + K K + + + + +W+ + +M + Sbjct: 448 EQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQ 507 Query: 596 --LYIENEGKMIMQDKLEKERNDAKNAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLE 653 E E KM Q++ +E+ + EE + E + + + EK ++++ K+ Sbjct: 508 EEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMR 567 Query: 654 DTENWLYEDGEDQPKQVYVDKLAELKNLGQPIKIRFQE---SEERPKLFEELGKQIQQYM 710 E + E E +Q + E K Q KIR QE E+ K++E+ K +Q Sbjct: 568 RQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEE 627 Query: 711 KI 712 K+ Sbjct: 628 KM 629 Score = 44.7 bits (104), Expect = 4e-04 Identities = 65/348 (18%), Positives = 155/348 (44%), Gaps = 35/348 (10%) Query: 503 SEENEEPM--ETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKK 560 +++ EE M + ++ + EEK+Q +QEE E++++ E K +E + K ++ Sbjct: 295 NQQQEEKMWRQEEKIQEWEEKIQ-EQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRR 353 Query: 561 MDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKL----EKERND 616 ++ K+ K++ +++W+ + ++ L E KM Q+K+ EK + + Sbjct: 354 QEEMMWEKEEKMRRL-------EEMMWEKEEKIREL----EEKMHEQEKIREQEEKRQEE 402 Query: 617 AKNAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDG-EDQPKQVYVDKL 675 K +E E K+ + EK ++++ ++ ++ + W E+ +Q K +K Sbjct: 403 EKIREQEKRQEQEAKMWRQEEKIREQEEK----IREQEKKMWRQEEKIHEQEKIREEEKR 458 Query: 676 AELKNL-GQPIKIRFQE----SEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAAD 730 E + + Q KIR QE +E+ E++ KQ ++ + ++E++ + Sbjct: 459 QEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKM 518 Query: 731 MTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKELTSTCSPIISKPKPKV 790 + EK + + + ++ ++ + + K E E K++E + + + K+ Sbjct: 519 WRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEK-----MRRQEEKI 573 Query: 791 EPPKEEQKNAEQNGPVDGQGDNPGPQAAEQGTDTAVPSDSDKKLPEMD 838 ++E+K EQ + Q + Q + + + ++K+ E + Sbjct: 574 R--EQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQE 619 >gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sapiens] Length = 570 Score = 54.3 bits (129), Expect = 5e-07 Identities = 42/197 (21%), Positives = 91/197 (46%), Gaps = 6/197 (3%) Query: 499 EVHKSEENEEPM-ETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSK 557 E K +E E M ++ +E+E+ +QEE E++++ E K +E E + K Sbjct: 374 EQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEK 433 Query: 558 DKKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDA 617 ++ ++ + ++ K++ + + +++ + + +M E EGKM Q+ +E+ + Sbjct: 434 MRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKM----GEQEGKMCEQEAKMQEQEEK 489 Query: 618 KNAVEEYVYEMRDKLSGEYEKFVSEDD-RNSFTLKLEDTENWLYEDGEDQPKQVYVDKLA 676 EE + E K+ + EK +++ K+ + E + E E +Q + Sbjct: 490 MRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQ 549 Query: 677 ELKNLGQPIKIRFQESE 693 E K Q +++R QE + Sbjct: 550 EEKMREQEVRLRQQEEK 566 Score = 49.3 bits (116), Expect = 1e-05 Identities = 48/276 (17%), Positives = 122/276 (44%), Gaps = 26/276 (9%) Query: 502 KSEENEEPM-ETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKK 560 K EE M E ++ + +E+M ++EE E +++ E E EE + ++++ Sbjct: 317 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQE 376 Query: 561 MDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAKNA 620 Q +AK +W+ + ++ E E K+ Q+++ +E+ + Sbjct: 377 KRQEQEAK-----------------MWRQEEKIR----EQEEKIREQEEMMQEQEEKMGE 415 Query: 621 VEEYVYEMRDKLSGEYEKFVSEDDR-NSFTLKLEDTENWLYEDGEDQPKQVYVDKLAELK 679 EE ++E +++ + EK ++++ K+ + E + E +++ Q +K+ E + Sbjct: 416 QEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIRE--QEEMMQEQEEKMGEQE 473 Query: 680 NLGQPIKIRFQESEERPKLFEE-LGKQIQQYMKIISSFKNKEDQYDHLDAADMTKVEKST 738 + + QE EE+ + EE + +Q ++ + + +E+ + + EK Sbjct: 474 GKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMC 533 Query: 739 NEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKE 774 + + + ++ ++ + V+ ++ E K++E Sbjct: 534 EQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQE 569 Score = 47.4 bits (111), Expect = 6e-05 Identities = 59/274 (21%), Positives = 116/274 (42%), Gaps = 29/274 (10%) Query: 505 ENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKKMDQP 564 + E+ E ++ +E+E+ +QEE +++ E K +E + K +++++ Sbjct: 293 QEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEE- 351 Query: 565 PQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAKNAVEEY 624 ++ K++ E ++ Q R+ E E KM Q++ +E+ + EE Sbjct: 352 KMHEQEKIREQEEKRQEEEKIREQEKRQ------EQEAKMWRQEEKIREQEEKIREQEEM 405 Query: 625 VYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKNLGQP 684 + E +K+ GE E+ K+ + E + E E +Q + E K Q Sbjct: 406 MQEQEEKM-GEQEE------------KMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQE 452 Query: 685 IKIRFQE---SEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAADMTKVEKSTNEA 741 KIR QE E+ K+ E+ GK +Q K+ ++++ + + EK E Sbjct: 453 EKIREQEEMMQEQEEKMGEQEGKMCEQEAKM-----QEQEEKMRRQEEKIREQEKKIREQ 507 Query: 742 MEWMNNKLNLQNKQSLTM-DPVVKSKEIEAKIKE 774 E + + + +Q M + K E E K++E Sbjct: 508 EEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE 541 >gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4 [Homo sapiens] Length = 2073 Score = 53.1 bits (126), Expect = 1e-06 Identities = 92/405 (22%), Positives = 161/405 (39%), Gaps = 60/405 (14%) Query: 436 RKEPFTLEAYYSSPQDLPYPDPAIAQFSVQKVTPQSDGSSSKVKVKVRVNVHGIFSVSSA 495 RK F L Y +P + P QK T + S S ++++ V G + Sbjct: 1265 RKTGFKLNLY--TPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLPQ- 1321 Query: 496 SLVEVHKSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAG 555 E ++ EE P+ + + E+ + + + E EE++++ E + E EE E G Sbjct: 1322 ---EENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEE--GGG 1376 Query: 556 SKDKKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERN 615 + +K D +K + + ST + D L+ + E E ++ E N Sbjct: 1377 NVEKDPDGAKSQEKEEPEISTE----------KEDSARLDDHEEEE-----EEDEEPSHN 1421 Query: 616 DAKNAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWL---YEDGEDQPKQVY- 671 + +A +E M S E EK E R SF LE+ E +L + G P+ + Sbjct: 1422 EDHDADDEDDSHME---SAEVEK--EELPRESFKEVLENQETFLDLNVQPGHSNPEVLMD 1476 Query: 672 --VDKLA----ELKNL-GQPIKIRFQESEERPKLFEELGKQIQQYMK-IISSFKNKEDQY 723 VD A E K L G P + ES+E P E+ KQ Q+ K + + FK Sbjct: 1477 CGVDLTASCNSEPKELAGDPEAV--PESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPAT 1534 Query: 724 DHLDAADMTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKELTSTCSPII 783 +D+ + V+ T E+ E Q T +++E ++ T Sbjct: 1535 MEIDSETVQAVQSLTQESSE-----------QDDTFQDCAETQEACRSLQNYTR------ 1577 Query: 784 SKPKPKVEPPKEEQKNAEQNGPVDGQGDNPGPQAAEQGTDTAVPS 828 + P++ ++ + ++ + PV +PG Q+ +VP+ Sbjct: 1578 ADQSPQIATTLDDCQQSDHSSPVSSVHSHPG-QSVRSVNSPSVPA 1621 Score = 37.7 bits (86), Expect = 0.045 Identities = 17/60 (28%), Positives = 32/60 (53%) Query: 505 ENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKKMDQP 564 E + +E + + EEE+ + D+EE EE++++ E + E EE E S ++ +P Sbjct: 1057 ERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKP 1116 Score = 36.6 bits (83), Expect = 0.100 Identities = 21/89 (23%), Positives = 41/89 (46%) Query: 489 IFSVSSASLVEVHKSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEE 548 + +S S E + E+ EE E ++ ++EE+ + ++EE E Q P K +S Sbjct: 1061 LLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVA 1120 Query: 549 METSQAGSKDKKMDQPPQAKKAKVKTSTV 577 ++ + KK + + + V T T+ Sbjct: 1121 IKRKRPFVLKKKRGRKRRRINSSVTTETI 1149 Score = 32.0 bits (71), Expect = 2.5 Identities = 70/360 (19%), Positives = 129/360 (35%), Gaps = 70/360 (19%) Query: 500 VHKSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDK 559 +H E E Q + ++ ++EE EE++++ E + E EE E + ++ Sbjct: 1046 LHSPESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEN 1105 Query: 560 KMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAKN 619 PP+ K + ++ I+ + +++ K ++R + Sbjct: 1106 IQSSPPRLTKPQ-----------------------SVAIKRKRPFVLKKKRGRKRRRINS 1142 Query: 620 AV-EEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLAEL 678 +V E + E + L+ E F + D+ E + EDG ++ + K + Sbjct: 1143 SVTTETISETTEVLN---EPFDNSDEERPMPQLEPTCEIEVEEDG----RKPVLRKAFQ- 1194 Query: 679 KNLGQPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAADMTKVE--- 735 QP K R E EE GK + N D +L E Sbjct: 1195 ---HQPGKKRQTEEEE--------GKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLK 1243 Query: 736 ------KSTNEAM-EWMNN-------KLNLQNKQSLTMDPVVK-SKEIEAKIKELTSTCS 780 K T + +W N KLNL M+P + + E + + E ++ S Sbjct: 1244 CKQVWPKGTKRGLSKWRQNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPS 1303 Query: 781 PIISKPKPKVEP----PKEEQKNAEQNGPVDGQGDNPGPQAAEQGTDTAVPSDSDKKLPE 836 PI + + K P+EE + E PV +P E+ D + + +++ E Sbjct: 1304 PIRIEEEVKETGEALLPQEENRREETCAPV-----SPNTSPGEKPEDDLIKPEEEEEEEE 1358 >gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapiens] Length = 436 Score = 52.4 bits (124), Expect = 2e-06 Identities = 55/245 (22%), Positives = 107/245 (43%), Gaps = 22/245 (8%) Query: 499 EVHKSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKD 558 ++ K EE E +Q K+EE+M +E+ +E+Q Q E + EE Q ++ Sbjct: 214 QMQKQEEQMGEQE-EQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQ---EE 269 Query: 559 KKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAK 618 + +Q Q K K +T + E + + E + E E +M Q++ +E+ + Sbjct: 270 QMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMR---EQEEQMREQEEQMREQEEQM 326 Query: 619 NAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLAEL 678 EE ++E ++++ + E+ ++++ + E E KQ + E Sbjct: 327 GKQEEQMWEQKEQMWEQKEQMWKQEEQ-------------MGEQEEQMQKQEEQVRKQEE 373 Query: 679 KNLGQPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAADMTKVEKST 738 + Q ++R QE + R K E++G+Q +Q + + +E+Q M K E+ Sbjct: 374 QMRKQEEQMRKQEEQMR-KQEEQMGEQKEQMGEQKEQMREQEEQMGE-QKEQMRKQEEHM 431 Query: 739 NEAME 743 E E Sbjct: 432 GEQKE 436 Score = 42.4 bits (98), Expect = 0.002 Identities = 41/258 (15%), Positives = 112/258 (43%), Gaps = 11/258 (4%) Query: 504 EENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKKMDQ 563 E+ + E + +E+E +QE E+++Q E + + +E + + + +K ++ Sbjct: 175 EQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEE 234 Query: 564 PPQAKKAKVKTSTVDLPIENQLLWQIDREMLNL--YIENEGKMIMQDKLEKERNDAKNAV 621 ++ +V+ + + + + + + +M + + + +++ K + E+ + Sbjct: 235 QMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQ 294 Query: 622 EEYVYEMRDKLSGEYEKF-VSEDDRNSFTLKLEDTENWLYEDGE---DQPKQVYVDKLAE 677 EE + E +++ + E+ E+ ++ E ++E E +Q +Q++ + Sbjct: 295 EEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQE--- 351 Query: 678 LKNLGQPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAADMTKVEKS 737 + +G+ + ++ E+ K E++ KQ +Q K + +E+Q M + ++ Sbjct: 352 -EQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGE-QKEQMGEQKEQ 409 Query: 738 TNEAMEWMNNKLNLQNKQ 755 E E M + KQ Sbjct: 410 MREQEEQMGEQKEQMRKQ 427 Score = 39.3 bits (90), Expect = 0.015 Identities = 70/325 (21%), Positives = 132/325 (40%), Gaps = 26/325 (8%) Query: 497 LVEVHKSE------ENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEME 550 LVE KSE E + +ETD+ +E QV ++E V EQ+ Q E + + E E Sbjct: 22 LVETEKSEIQLHIKELKRKLETDKIPLPQEG-QVREQEGQVREQEGQV-REQEGQVREQE 79 Query: 551 TSQAGSKDKKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKL 610 + + +Q Q ++ + + + + Q Q+ RE E EG++ Q+ Sbjct: 80 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQ-EGQV-REQEGQVREQEGQVREQEGQ 137 Query: 611 EKERNDAKNAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQV 670 +E+ E V E ++ E E V E + ++ + E + E E Q ++ Sbjct: 138 VREQEGQVREQEGQVREQEGQVR-EQEGQVREQEG-----QVREQEGQVREQ-EGQVREQ 190 Query: 671 YVDKLAELKNLGQPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLD--- 727 + +G+ + ++ E+ K E++G+Q +Q K +E+Q + Sbjct: 191 EGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQV 250 Query: 728 ---AADMTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKELTSTCSPIIS 784 M K E+ E E M + KQ + ++ E E +++E Sbjct: 251 QKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEE 310 Query: 785 KPKPKVEPPKEEQKNAEQNGPVDGQ 809 + + + E +E++ EQ G + Q Sbjct: 311 QMREQEEQMREQE---EQMGKQEEQ 332 Score = 36.6 bits (83), Expect = 0.100 Identities = 27/149 (18%), Positives = 71/149 (47%), Gaps = 11/149 (7%) Query: 497 LVEVHKSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGS 556 L + ++E+ E+ E ++ +E+E+ +QEE E+++Q E + +E + + Sbjct: 279 LKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWE--Q 336 Query: 557 KDKKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERND 616 K++ +Q Q K + + E + Q E + + E +M Q++ +++ + Sbjct: 337 KEQMWEQKEQMWKQEEQMG------EQEEQMQKQEEQVR---KQEEQMRKQEEQMRKQEE 387 Query: 617 AKNAVEEYVYEMRDKLSGEYEKFVSEDDR 645 EE + E ++++ + E+ ++++ Sbjct: 388 QMRKQEEQMGEQKEQMGEQKEQMREQEEQ 416 >gi|239752551 PREDICTED: hypothetical protein [Homo sapiens] Length = 238 Score = 52.0 bits (123), Expect = 2e-06 Identities = 50/218 (22%), Positives = 97/218 (44%), Gaps = 11/218 (5%) Query: 505 ENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKKMDQP 564 E E E ++ +EEE+M +QEE E++++ E K +E + + K + ++ Sbjct: 3 EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 62 Query: 565 PQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAKNAVEEY 624 ++ K+ LP + + +W+ D E L E + M ++EK R + K EE Sbjct: 63 MWEQEEKM-WEQQRLPEQKEKMWEQD-ERLREKEERMREQKMWQQVEKMR-EKKKTQEEK 119 Query: 625 VYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKNLGQP 684 + E +K+ + E +++ K+++ E ++E E +Q + E K GQ Sbjct: 120 MQEQEEKMQEQEEMMWEQEE------KMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQE 173 Query: 685 IKIRFQE--SEERPKLFEELGKQIQQYMKIISSFKNKE 720 K+R E E + + Q+ M++ KN + Sbjct: 174 EKMRDVEPAGGEAGEGSPQDNPTAQEIMQLFCGMKNAQ 211 Score = 46.6 bits (109), Expect = 1e-04 Identities = 45/184 (24%), Positives = 78/184 (42%), Gaps = 14/184 (7%) Query: 499 EVHKSEENEEPMETDQNAK---EEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAG 555 E K EE M +Q K +EEKM+ +E+ +E++ Q E E EE Q Sbjct: 9 EREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEE 68 Query: 556 SKDKKMDQPPQAKKAKVKTSTV---DLPIENQLLWQIDREML-------NLYIENEGKMI 605 ++ P Q +K + + + + Q +WQ +M E E KM Sbjct: 69 KMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEKMQ 128 Query: 606 MQDKLEKERNDAKNAVEEYVYEMRDKLSGEYEKFVSEDDR-NSFTLKLEDTENWLYEDGE 664 Q+++ E+ + EE ++E +K+ + EK ++++ K+ D E E GE Sbjct: 129 EQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVEPAGGEAGE 188 Query: 665 DQPK 668 P+ Sbjct: 189 GSPQ 192 Score = 45.8 bits (107), Expect = 2e-04 Identities = 41/193 (21%), Positives = 93/193 (48%), Gaps = 16/193 (8%) Query: 517 KEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKKMDQPPQAKKAKVKTST 576 +EEE+M+ ++E+ EE++ E K + +E + + K + ++ Q ++ K+ Sbjct: 2 REEERMR-EREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 60 Query: 577 VDLPIENQLLWQIDREMLNLYIENEGKMIMQDK--LEKERNDAKNAVEEYVYEMRDKLSG 634 + + + +W+ R E + KM QD+ EKE + + + V +MR+K Sbjct: 61 EKMWEQEEKMWEQQR-----LPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKT 115 Query: 635 EYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKNLGQPIKIRFQESEE 694 + EK +++ K+++ E ++E E +Q +K+ E + + + + +E EE Sbjct: 116 QEEKMQEQEE------KMQEQEEMMWEQEEKMQEQ--EEKMWEQEEKMREQEEKMREQEE 167 Query: 695 RPKLFEELGKQIQ 707 + + EE + ++ Sbjct: 168 KMQGQEEKMRDVE 180 >gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like protein 6 [Homo sapiens] Length = 724 Score = 50.8 bits (120), Expect = 5e-06 Identities = 49/247 (19%), Positives = 111/247 (44%), Gaps = 27/247 (10%) Query: 505 ENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEM--------------- 549 + E+ E ++ +E+E+ QEE + EQ++ E + E EEM Sbjct: 482 QEEKIREQEEKIREQEEKMWRQEEK-IHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWR 540 Query: 550 ---ETSQAGSKDKKMDQPPQAKKAKVKTSTVDLPIENQLLWQID---REMLNLYIENEGK 603 + + K +K ++ ++ K+ + + + +W+ + RE E E K Sbjct: 541 QKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEK 600 Query: 604 MIMQDKLEKERNDAKNAVEEYVYEMRDKLSGEYEKFVSEDDR-NSFTLKLEDTENWLYED 662 + Q+++ +E+ + EE + E +K+ + EK ++++ K+ + E + E Sbjct: 601 IREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIRE- 659 Query: 663 GEDQPKQVYVDKLAELKNLGQPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQ 722 +++ Q +K+ E + + + QE EE+ + EE K +Q +++ + ++ Sbjct: 660 -QEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEE--KMWEQEVRLRQQEEKMQEH 716 Query: 723 YDHLDAA 729 +HL+AA Sbjct: 717 QEHLEAA 723 Score = 49.3 bits (116), Expect = 1e-05 Identities = 67/350 (19%), Positives = 155/350 (44%), Gaps = 30/350 (8%) Query: 503 SEENEEPM--ETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKK 560 +++ EE M + ++ + EEK+Q +QEE E++++ E K +E + K ++ Sbjct: 356 NQQQEEKMWRQEEKIQEWEEKIQ-EQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRR 414 Query: 561 MDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKL----EKERND 616 ++ K+ K++ + +++W+ + ++ L E KM Q+K+ EK + + Sbjct: 415 QEEMMWEKEEKMRR-------QEEMMWEKEEKIREL----EEKMHEQEKIREQEEKRQEE 463 Query: 617 AKNAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDG-EDQPKQVYVDKL 675 K +E E K+ + EK ++++ ++ ++ + W E+ +Q K +K Sbjct: 464 EKIREQEKRQEQEAKMWRQEEKIREQEEK----IREQEEKMWRQEEKIHEQEKIREEEKR 519 Query: 676 AELKNL-GQPIKIRFQES--EERPKLFEE---LGKQIQQYMKIISSFKNKEDQYDHLDAA 729 E + + Q KIR QE ++ K+ E+ + KQ ++ + ++E++ + Sbjct: 520 QEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEK 579 Query: 730 DMTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKELTSTCSPIISKPKPK 789 + EK + + + ++ ++ +T + K E E K+ E K + + Sbjct: 580 VWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQ 639 Query: 790 VEPPKEEQKN-AEQNGPVDGQGDNPGPQAAEQGTDTAVPSDSDKKLPEMD 838 E +E++K EQ + Q + Q + + ++K+ E + Sbjct: 640 EEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQE 689 Score = 48.5 bits (114), Expect = 3e-05 Identities = 28/135 (20%), Positives = 66/135 (48%), Gaps = 11/135 (8%) Query: 504 EENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKKMDQ 563 E+ E+ E ++ +E+E+M +QEE E++++ E K + +E + + K ++ ++ Sbjct: 589 EQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEK 648 Query: 564 PPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAKNAVEE 623 + ++ K++ + + + +W E E KM Q++ +E+ + EE Sbjct: 649 KIREQEEKIREQEEMMQEQEEKMW-----------EQEEKMCEQEEKMQEQEEKMRRQEE 697 Query: 624 YVYEMRDKLSGEYEK 638 ++E +L + EK Sbjct: 698 KMWEQEVRLRQQEEK 712 Score = 47.4 bits (111), Expect = 6e-05 Identities = 59/284 (20%), Positives = 125/284 (44%), Gaps = 18/284 (6%) Query: 502 KSEENEEPM-ETDQNAKEEEKMQVDQEEP--HVEEQQQQTPAENKAESEEMETSQAGSKD 558 K EE M E ++ + +E+M ++EE +EE+ + + E + E + ++ Sbjct: 411 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQE 470 Query: 559 KKMDQPPQ--AKKAKVKTSTVDLPIENQLLWQIDREMLNL-YIENEGKMIMQDKLEKERN 615 K+ +Q + ++ K++ + + + +W+ + ++ I E K Q++ E R Sbjct: 471 KRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEK--RQEQEEMWRQ 528 Query: 616 DAKNAVEEYVYEMRDKLSGEYEKFVSEDDRN-SFTLKLEDTENWLYEDGEDQPKQVYVDK 674 + K +E ++ ++K+ + EK ++++ K+ D E + E E +Q + Sbjct: 529 EEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIR 588 Query: 675 LAELKNLGQPIKIRFQE---SEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAADM 731 E K Q KIR QE E+ K+ E+ K +Q K+ ++++ + Sbjct: 589 EQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKM-----QEQEEKMRRQEEKI 643 Query: 732 TKVEKSTNEAMEWMNNKLNLQNKQSLTM-DPVVKSKEIEAKIKE 774 + EK E E + + + +Q M + K E E K++E Sbjct: 644 REQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE 687 Score = 30.4 bits (67), Expect = 7.1 Identities = 19/79 (24%), Positives = 39/79 (49%), Gaps = 1/79 (1%) Query: 502 KSEENEEPMET-DQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKK 560 K +E EE M ++ +E+EK +QEE E+++ E K +E + + K ++ Sbjct: 628 KMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE 687 Query: 561 MDQPPQAKKAKVKTSTVDL 579 ++ + ++ K+ V L Sbjct: 688 QEEKMRRQEEKMWEQEVRL 706 >gi|8922950 meiosis-specific nuclear structural 1 [Homo sapiens] Length = 495 Score = 49.7 bits (117), Expect = 1e-05 Identities = 70/322 (21%), Positives = 142/322 (44%), Gaps = 49/322 (15%) Query: 500 VHKSEENEEPMETDQNAKEEEKMQVD----QEEPHVEEQQQQTPAENKAESEEMETSQAG 555 + K+EEN+ E K+EEK+ ++ + E +E+ +Q EN E E+E Sbjct: 73 IQKAEENKRLKELQ--LKQEEKLAMELAKLKHESLKDEKMRQQVRENSIELRELEKKLKA 130 Query: 556 SKDKKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDK-LEKER 614 + K A+K +K + + D E+ +E ++I ++ E +R Sbjct: 131 AYMNKERAAQIAEKDAIKYEQM----------KRDAEIAKTMMEEHKRIIKEENAAEDKR 180 Query: 615 NDAKNA----VEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQV 670 N AK +E+ + E K YE+ + E L +++ +YE+ + + +Q Sbjct: 181 NKAKAQYYLDLEKQLEEQEKKKQEAYEQLLKE------KLMIDEIVRKIYEEDQLEKQQ- 233 Query: 671 YVDKLAELKNLGQPIKIRFQESEE--RPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDA 728 KL ++ + + I+ FQ+ + R K EE+ ++ ++ ++ + + +E+ Sbjct: 234 ---KLEKMNAMRRYIE-EFQKEQALWRKKKREEMEEENRKIIEFANMQQQREED------ 283 Query: 729 ADMTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKE-IEAKIKELTSTCSPIISKPK 787 M KV+++ + +L LQN + ++ +++ +E +E +EL I K K Sbjct: 284 -RMAKVQENEEK-------RLQLQNALTQKLEEMLRQREDLEQVRQELYQEEQAEIYKSK 335 Query: 788 PKVEPPKEEQKNAEQNGPVDGQ 809 K E K+ +K E + Q Sbjct: 336 LKEEAEKKLRKQKEMKQDFEEQ 357 Score = 37.7 bits (86), Expect = 0.045 Identities = 53/242 (21%), Positives = 101/242 (41%), Gaps = 35/242 (14%) Query: 502 KSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKKM 561 K +ENEE QNA ++ ++ ++ +E+ +Q+ E +AE + SK K+ Sbjct: 287 KVQENEEKRLQLQNALTQKLEEMLRQREDLEQVRQELYQEEQAEIYK-------SKLKEE 339 Query: 562 DQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAKNAV 621 + K+ ++K + +L+ Q +E EN K ++ E +R + NA Sbjct: 340 AEKKLRKQKEMKQDFEEQMALKELVLQAAKE----EEENFRKTMLAKFAEDDRIELMNAQ 395 Query: 622 EEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKNL 681 ++ + ++ + + EK + E + K + E W + Q +Q +++ + E Sbjct: 396 KQRMKQLEHRRA--VEKLIEERRQQFLADKQRELEEWQLQ----QRRQGFINAIIE---- 445 Query: 682 GQPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAADMTKVEKSTNEA 741 EER KL +E + Y+ KED D L + KV + +E Sbjct: 446 -----------EERLKLLKEHATNLLGYLP--KGVFKKEDDIDLL-GEEFRKVYQQRSEI 491 Query: 742 ME 743 E Sbjct: 492 CE 493 >gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 750 Score = 48.9 bits (115), Expect = 2e-05 Identities = 66/353 (18%), Positives = 141/353 (39%), Gaps = 28/353 (7%) Query: 504 EENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKKMDQ 563 E+ E+ E ++ + +E+M ++EE +++ E K +E + K ++ ++ Sbjct: 325 EQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEE 384 Query: 564 PPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYI-------ENEGKMIMQDKLEKERND 616 K+ K++ + + ++ Q ++ I E E KM Q++ +E+ + Sbjct: 385 MMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEE 444 Query: 617 AKNAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLA 676 E+ ++ +K+ E EK E+ R E E W E+ + ++++ K Sbjct: 445 KIREQEKKMWRQEEKIH-EQEKIREEEKRQ------EQEEMWRQEEKIHEQEEIWRQK-- 495 Query: 677 ELKNLGQPIKIRFQES----------EERPKLFEELGKQIQQYMKIISSFKNKEDQYDHL 726 K Q KIR QE E+ K+ E+ K +Q KI + ++ Sbjct: 496 -EKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMH 554 Query: 727 DAADMTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKELTSTCSPIISKP 786 + + + EK + + + ++ ++ K +E E K +E K Sbjct: 555 EQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKI 614 Query: 787 KPKVEPPKE-EQKNAEQNGPVDGQGDNPGPQAAEQGTDTAVPSDSDKKLPEMD 838 + + E +E E+K EQ + Q + Q + G + ++K+ E + Sbjct: 615 REQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQE 667 Score = 47.0 bits (110), Expect = 7e-05 Identities = 28/135 (20%), Positives = 65/135 (48%), Gaps = 11/135 (8%) Query: 504 EENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKKMDQ 563 E+ E+ E ++ +E+E+M +QEE E++++ E K + +E + K ++ ++ Sbjct: 623 EQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEK 682 Query: 564 PPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAKNAVEE 623 + ++ K++ + + + +W E E KM Q++ +E+ + EE Sbjct: 683 KIREQEEKIREQEEMMQEQEEKMW-----------EQEEKMCEQEEKMQEQEEKMRRQEE 731 Query: 624 YVYEMRDKLSGEYEK 638 ++E +L + EK Sbjct: 732 KMWEQEVRLRQQEEK 746 Score = 46.2 bits (108), Expect = 1e-04 Identities = 65/277 (23%), Positives = 117/277 (42%), Gaps = 25/277 (9%) Query: 505 ENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKKMDQP 564 + E+ E ++ +E+EK QEE + EQ++ E + E EEM +++K+ + Sbjct: 435 QEEKIREQEEKIREQEKKMWRQEEK-IHEQEKIREEEKRQEQEEM-----WRQEEKIHEQ 488 Query: 565 PQAKKAKVKTSTVDLPIENQ--LLWQID---REMLNLYIENEGKMIMQDKLEKERNDAKN 619 + + K K + I Q +W+ + RE E E KM Q+ EK R + Sbjct: 489 EEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQE--EKIREQEEM 546 Query: 620 AVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLAELK 679 EE ++K+ E ++ ED K+ + E ++ E +Q + E K Sbjct: 547 WREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEK 606 Query: 680 NLGQPIKIRFQES--EERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAADMTKVEKS 737 Q KIR QE +E+ + E ++I++ ++ + K + + K+++ Sbjct: 607 MWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQ 666 Query: 738 TNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKE 774 E M K+ Q K K +E E KI+E Sbjct: 667 -EETMWRQEEKIREQEK---------KIREQEEKIRE 693 Score = 45.8 bits (107), Expect = 2e-04 Identities = 42/197 (21%), Positives = 89/197 (45%), Gaps = 13/197 (6%) Query: 499 EVHKSEENEEPM-ETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSK 557 E K +E E+ M ++ +E+E+ QEE E+++++ E K +E + + K Sbjct: 561 EEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEK 620 Query: 558 DKKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDA 617 ++ ++ + ++ K++ E + + Q E + E E KM Q++ +E+ + Sbjct: 621 IQEQEEKIREQEEKIR--------EQEEMTQEQEEKMG---EQEEKMCEQEEKMQEQEET 669 Query: 618 KNAVEEYVYEMRDKLSGEYEKFVSEDD-RNSFTLKLEDTENWLYEDGEDQPKQVYVDKLA 676 EE + E K+ + EK +++ K+ + E + E E +Q + Sbjct: 670 MWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQ 729 Query: 677 ELKNLGQPIKIRFQESE 693 E K Q +++R QE + Sbjct: 730 EEKMWEQEVRLRQQEEK 746 Score = 45.1 bits (105), Expect = 3e-04 Identities = 60/294 (20%), Positives = 123/294 (41%), Gaps = 27/294 (9%) Query: 502 KSEENEEPMETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKKM 561 K E E+ E ++ +EEEK +QE+ +E + E E EE Q +KKM Sbjct: 399 KMHEQEKIREQEEKRQEEEK-IREQEKRQEQEAKMWRQEEKIREQEEKIREQ----EKKM 453 Query: 562 DQPPQAKKAKVKTSTVDLPIENQLLWQID---REMLNLYIENEGKMIMQDKLEKERNDAK 618 + + + K + E + +W+ + E ++ + E ++K+ K+ Sbjct: 454 WRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVW 513 Query: 619 NAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYED---GEDQPKQVYVDKL 675 EE + E +K+ + EK ++++ ++ E ++E E++ +Q DK+ Sbjct: 514 RQ-EEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKM 572 Query: 676 ---------AELKNLGQPIKIRFQE---SEERPKLF---EELGKQIQQYMKIISSFKNKE 720 E K Q KIR QE E+ K++ E++ +Q ++ + + +E Sbjct: 573 WRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQE 632 Query: 721 DQYDHLDAADMTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKE 774 ++ + + EK + + + +Q ++ K +E E KI+E Sbjct: 633 EKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIRE 686 Score = 44.3 bits (103), Expect = 5e-04 Identities = 70/309 (22%), Positives = 131/309 (42%), Gaps = 56/309 (18%) Query: 503 SEENEEPM--ETDQNAKEEEKMQVDQEEPHVEEQQQQTPAENKAESEEMETSQAGSKDKK 560 +++ EE M + ++ + EEK+Q +E+ +E++ + E EEM K++K Sbjct: 295 NQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEM----MWEKEEK 350 Query: 561 MDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAKNA 620 M + + +++W E E KM Q+++ E+ + Sbjct: 351 MRR------------------QEEMMW-----------EKEEKMRRQEEMMWEKEEKMRR 381 Query: 621 VEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKN 680 EE ++E +K+ EK ++ K+ + E E E++ ++ + E K Sbjct: 382 QEEMMWEKEEKIRELEEKMHEQE-------KIREQEEKRQE--EEKIREQEKRQEQEAKM 432 Query: 681 LGQPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAADMTKVEKSTNE 740 Q KIR QE K+ E+ K +Q KI K +E++ + +M + E+ +E Sbjct: 433 WRQEEKIREQEE----KIREQEKKMWRQEEKIHEQEKIREEE-KRQEQEEMWRQEEKIHE 487 Query: 741 AME-W-MNNKLNLQNKQSLTMDPVV-----KSKEIEAKIKELTSTCSPIISKPKPKVEPP 793 E W K++ Q ++ + V K +E E KI+E K + + E Sbjct: 488 QEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMW 547 Query: 794 KEEQKNAEQ 802 +EE+K EQ Sbjct: 548 REEEKMHEQ 556 Score = 44.3 bits (103), Expect = 5e-04 Identities = 57/290 (19%), Positives = 117/290 (40%), Gaps = 33/290 (11%) Query: 502 KSEENEEPM-ETDQNAKEEEKMQVDQEEP--HVEEQQQQTPAENKAESEEMETSQAGSKD 558 K EE M E ++ + +E+M ++EE +EE+ + + E + E + ++ Sbjct: 364 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQE 423 Query: 559 KKMDQPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQD----KLEKER 614 K+ +Q + + + K RE E E KM Q+ + EK R Sbjct: 424 KRQEQEAKMWRQEEKI----------------REQEEKIREQEKKMWRQEEKIHEQEKIR 467 Query: 615 NDAKNAVEEYVYEMRDKLSGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVDK 674 + K +E ++ +K+ + E + ++ + K+ E ++ E +Q + Sbjct: 468 EEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIR 527 Query: 675 LAELKNLGQPIKIRFQES--------EERPKLFEELGKQIQQ--YMKIISSFKNKEDQYD 724 E K Q KIR QE E+ K++EE +Q Q+ + + +E++ Sbjct: 528 EQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVW 587 Query: 725 HLDAADMTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKE 774 + + EK + + + ++ ++ + K +E E KI+E Sbjct: 588 RQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIRE 637 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.312 0.129 0.360 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 31,315,269 Number of Sequences: 37866 Number of extensions: 1474647 Number of successful extensions: 12633 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 201 Number of HSP's successfully gapped in prelim test: 540 Number of HSP's that attempted gapping in prelim test: 7884 Number of HSP's gapped (non-prelim): 3227 length of query: 840 length of database: 18,247,518 effective HSP length: 111 effective length of query: 729 effective length of database: 14,044,392 effective search space: 10238361768 effective search space used: 10238361768 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.