Guide to the Human Genome
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Search of human proteins with 38327034

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|38327034 ubiquitination factor E4B isoform 2 [Homo sapiens]
         (1173 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|38327034 ubiquitination factor E4B isoform 2 [Homo sapiens]       2336   0.0  
gi|157739864 ubiquitination factor E4B isoform 1 [Homo sapiens]      1820   0.0  
gi|38327029 ubiquitination factor E4A [Homo sapiens]                  277   5e-74
gi|119943102 CREB binding protein isoform b [Homo sapiens]             43   0.002
gi|119943104 CREB binding protein isoform a [Homo sapiens]             43   0.002
gi|7662344 U-box domain containing 5 isoform a [Homo sapiens]          40   0.013
gi|40806196 U-box domain containing 5 isoform b [Homo sapiens]         40   0.013
gi|4503257 death-domain associated protein isoform a [Homo sapiens]    39   0.022
gi|215422388 death-domain associated protein isoform a [Homo sap...    39   0.022
gi|215422366 death-domain associated protein isoform b [Homo sap...    39   0.022
gi|56181387 STIP1 homology and U-box containing protein 1 [Homo ...    39   0.029
gi|40068059 CBF1 interacting corepressor [Homo sapiens]                38   0.050
gi|50345997 E1A binding protein p300 [Homo sapiens]                    38   0.050
gi|189571685 WD repeat, sterile alpha motif and U-box domain con...    38   0.050
gi|189571683 WD repeat, sterile alpha motif and U-box domain con...    38   0.050
gi|189571681 WD repeat, sterile alpha motif and U-box domain con...    38   0.050
gi|126090892 aggrecan isoform 2 precursor [Homo sapiens]               38   0.065
gi|126090883 aggrecan isoform 1 precursor [Homo sapiens]               38   0.065
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]         38   0.065
gi|150010577 tyrosine kinase, non-receptor, 1 [Homo sapiens]           38   0.065
gi|19924099 synapsin I isoform Ia [Homo sapiens]                       37   0.085
gi|19924097 synapsin I isoform Ib [Homo sapiens]                       37   0.085
gi|13994287 BTE-binding protein 4 [Homo sapiens]                       37   0.14 
gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [...    37   0.14 
gi|51093836 hypothetical protein LOC126859 isoform 1 [Homo sapiens]    37   0.14 
gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithor...    36   0.19 
gi|38176300 nestin [Homo sapiens]                                      36   0.25 
gi|138175817 zinc finger protein 236 [Homo sapiens]                    36   0.25 
gi|40538736 RAN binding protein 10 [Homo sapiens]                      35   0.32 
gi|239742580 PREDICTED: similar to Putative POM121-like protein ...    35   0.42 

>gi|38327034 ubiquitination factor E4B isoform 2 [Homo sapiens]
          Length = 1173

 Score = 2336 bits (6053), Expect = 0.0
 Identities = 1173/1173 (100%), Positives = 1173/1173 (100%)

Query: 1    MEELSADEIRRRRLARLAGGQTSQPTTPLTSPQRENPPGPPIAASAPGPSQSLGLNVHNM 60
            MEELSADEIRRRRLARLAGGQTSQPTTPLTSPQRENPPGPPIAASAPGPSQSLGLNVHNM
Sbjct: 1    MEELSADEIRRRRLARLAGGQTSQPTTPLTSPQRENPPGPPIAASAPGPSQSLGLNVHNM 60

Query: 61   TPATSPIGASGVAHRSQSSEGVSSLSSSPSNSLETQSQSLSRSQSMDIDGVSCEKSMSQV 120
            TPATSPIGASGVAHRSQSSEGVSSLSSSPSNSLETQSQSLSRSQSMDIDGVSCEKSMSQV
Sbjct: 61   TPATSPIGASGVAHRSQSSEGVSSLSSSPSNSLETQSQSLSRSQSMDIDGVSCEKSMSQV 120

Query: 121  DVDSGIENMEVDENDRREKRSLSDKEPSSGPEVSEEQALQLVCKIFRVSWKDRDRDVIFL 180
            DVDSGIENMEVDENDRREKRSLSDKEPSSGPEVSEEQALQLVCKIFRVSWKDRDRDVIFL
Sbjct: 121  DVDSGIENMEVDENDRREKRSLSDKEPSSGPEVSEEQALQLVCKIFRVSWKDRDRDVIFL 180

Query: 181  SSLSAQFKQNPKEVFSDFKDLIGQILMEVLMMSTQTRDENPFASLTATSQPIAAAARSPD 240
            SSLSAQFKQNPKEVFSDFKDLIGQILMEVLMMSTQTRDENPFASLTATSQPIAAAARSPD
Sbjct: 181  SSLSAQFKQNPKEVFSDFKDLIGQILMEVLMMSTQTRDENPFASLTATSQPIAAAARSPD 240

Query: 241  RNLLLNTGSNPGTSPMFCSVASFGASSLSSLGASGGASNWDSYSDHFTIETCKETDMLNY 300
            RNLLLNTGSNPGTSPMFCSVASFGASSLSSLGASGGASNWDSYSDHFTIETCKETDMLNY
Sbjct: 241  RNLLLNTGSNPGTSPMFCSVASFGASSLSSLGASGGASNWDSYSDHFTIETCKETDMLNY 300

Query: 301  LIECFDRVGIEEKKAPKMCSQPAVSQLLSNIRSQCISHTALVLQGSLTQPRSLQQPSFLV 360
            LIECFDRVGIEEKKAPKMCSQPAVSQLLSNIRSQCISHTALVLQGSLTQPRSLQQPSFLV
Sbjct: 301  LIECFDRVGIEEKKAPKMCSQPAVSQLLSNIRSQCISHTALVLQGSLTQPRSLQQPSFLV 360

Query: 361  PYMLCRNLPYGFIQELVRTTHQDEEVFKQIFIPILQGLALAAKECSLDSDYFKYPLMALG 420
            PYMLCRNLPYGFIQELVRTTHQDEEVFKQIFIPILQGLALAAKECSLDSDYFKYPLMALG
Sbjct: 361  PYMLCRNLPYGFIQELVRTTHQDEEVFKQIFIPILQGLALAAKECSLDSDYFKYPLMALG 420

Query: 421  ELCETKFGKTHPVCNLVASLRLWLPKSLSPGCGRELQRLSYLGAFFSFSVFAEDDVKVVE 480
            ELCETKFGKTHPVCNLVASLRLWLPKSLSPGCGRELQRLSYLGAFFSFSVFAEDDVKVVE
Sbjct: 421  ELCETKFGKTHPVCNLVASLRLWLPKSLSPGCGRELQRLSYLGAFFSFSVFAEDDVKVVE 480

Query: 481  KYFSGPAITLENTRVVSQSLQHYLELGRQELFKILHSILLNGETREAALSYMAAVVNANM 540
            KYFSGPAITLENTRVVSQSLQHYLELGRQELFKILHSILLNGETREAALSYMAAVVNANM
Sbjct: 481  KYFSGPAITLENTRVVSQSLQHYLELGRQELFKILHSILLNGETREAALSYMAAVVNANM 540

Query: 541  KKAQMQTDDRLVSTDGFMLNFLWVLQQLSTKIKLETVDPTYIFHPRCRITLPNDETRVNA 600
            KKAQMQTDDRLVSTDGFMLNFLWVLQQLSTKIKLETVDPTYIFHPRCRITLPNDETRVNA
Sbjct: 541  KKAQMQTDDRLVSTDGFMLNFLWVLQQLSTKIKLETVDPTYIFHPRCRITLPNDETRVNA 600

Query: 601  TMEDVNDWLTELYGDQPPFSEPKFPTECFFLTLHAHHLSILPSCRRYIRRLRAIRELNRT 660
            TMEDVNDWLTELYGDQPPFSEPKFPTECFFLTLHAHHLSILPSCRRYIRRLRAIRELNRT
Sbjct: 601  TMEDVNDWLTELYGDQPPFSEPKFPTECFFLTLHAHHLSILPSCRRYIRRLRAIRELNRT 660

Query: 661  VEDLKNNESQWKDSPLATRHREMLKRCKTQLKKLVRCKACADAGLLDESFLRRCLNFYGL 720
            VEDLKNNESQWKDSPLATRHREMLKRCKTQLKKLVRCKACADAGLLDESFLRRCLNFYGL
Sbjct: 661  VEDLKNNESQWKDSPLATRHREMLKRCKTQLKKLVRCKACADAGLLDESFLRRCLNFYGL 720

Query: 721  LIQLLLRILDPAYPDITLPLNSDVPKVFAALPEFYVEDVAEFLFFIVQYSPQALYEPCTQ 780
            LIQLLLRILDPAYPDITLPLNSDVPKVFAALPEFYVEDVAEFLFFIVQYSPQALYEPCTQ
Sbjct: 721  LIQLLLRILDPAYPDITLPLNSDVPKVFAALPEFYVEDVAEFLFFIVQYSPQALYEPCTQ 780

Query: 781  DIVMFLVVMLCNQNYIRNPYLVAKLVEVMFMTNPAVQPRTQKFFEMIENHPLSTKLLVPS 840
            DIVMFLVVMLCNQNYIRNPYLVAKLVEVMFMTNPAVQPRTQKFFEMIENHPLSTKLLVPS
Sbjct: 781  DIVMFLVVMLCNQNYIRNPYLVAKLVEVMFMTNPAVQPRTQKFFEMIENHPLSTKLLVPS 840

Query: 841  LMKFYTDVEHTGATSEFYDKFTIRYHISTIFKSLWQNIAHHGTFMEEFNSGKQFVRYINM 900
            LMKFYTDVEHTGATSEFYDKFTIRYHISTIFKSLWQNIAHHGTFMEEFNSGKQFVRYINM
Sbjct: 841  LMKFYTDVEHTGATSEFYDKFTIRYHISTIFKSLWQNIAHHGTFMEEFNSGKQFVRYINM 900

Query: 901  LINDTTFLLDESLESLKRIHEVQEEMKNKEQWDQLPRDQQQARQSQLAQDERVSRSYLAL 960
            LINDTTFLLDESLESLKRIHEVQEEMKNKEQWDQLPRDQQQARQSQLAQDERVSRSYLAL
Sbjct: 901  LINDTTFLLDESLESLKRIHEVQEEMKNKEQWDQLPRDQQQARQSQLAQDERVSRSYLAL 960

Query: 961  ATETVDMFHILTKQVQKPFLRPELGPRLAAMLNFNLQQLCGPKCRDLKVENPEKYGFEPK 1020
            ATETVDMFHILTKQVQKPFLRPELGPRLAAMLNFNLQQLCGPKCRDLKVENPEKYGFEPK
Sbjct: 961  ATETVDMFHILTKQVQKPFLRPELGPRLAAMLNFNLQQLCGPKCRDLKVENPEKYGFEPK 1020

Query: 1021 KLLDQLTDIYLQLDCARFAKAIADDQRSYSKELFEEVISKMRKAGIKSTIAIEKFKLLAE 1080
            KLLDQLTDIYLQLDCARFAKAIADDQRSYSKELFEEVISKMRKAGIKSTIAIEKFKLLAE
Sbjct: 1021 KLLDQLTDIYLQLDCARFAKAIADDQRSYSKELFEEVISKMRKAGIKSTIAIEKFKLLAE 1080

Query: 1081 KVEEIVAKNARAEIDYSDAPDEFRDPLMDTLMTDPVRLPSGTIMDRSIILRHLLNSPTDP 1140
            KVEEIVAKNARAEIDYSDAPDEFRDPLMDTLMTDPVRLPSGTIMDRSIILRHLLNSPTDP
Sbjct: 1081 KVEEIVAKNARAEIDYSDAPDEFRDPLMDTLMTDPVRLPSGTIMDRSIILRHLLNSPTDP 1140

Query: 1141 FNRQTLTESMLEPVPELKEQIQAWMREKQNSDH 1173
            FNRQTLTESMLEPVPELKEQIQAWMREKQNSDH
Sbjct: 1141 FNRQTLTESMLEPVPELKEQIQAWMREKQNSDH 1173


>gi|157739864 ubiquitination factor E4B isoform 1 [Homo sapiens]
          Length = 1302

 Score = 1820 bits (4714), Expect = 0.0
 Identities = 919/948 (96%), Positives = 920/948 (97%), Gaps = 6/948 (0%)

Query: 229  SQPIAAAARSPDRNLLLNTGSNPGTSPMFCSVASFGASSLS---SLGASGGASNWDSYSD 285
            S P A  A S  R    +TG  P   P   S  S   SSL    SLGASGGASNWDSYSD
Sbjct: 358  SSPQAVPASS-SRQRPSSTG--PPLPPASPSATSRRPSSLRISPSLGASGGASNWDSYSD 414

Query: 286  HFTIETCKETDMLNYLIECFDRVGIEEKKAPKMCSQPAVSQLLSNIRSQCISHTALVLQG 345
            HFTIETCKETDMLNYLIECFDRVGIEEKKAPKMCSQPAVSQLLSNIRSQCISHTALVLQG
Sbjct: 415  HFTIETCKETDMLNYLIECFDRVGIEEKKAPKMCSQPAVSQLLSNIRSQCISHTALVLQG 474

Query: 346  SLTQPRSLQQPSFLVPYMLCRNLPYGFIQELVRTTHQDEEVFKQIFIPILQGLALAAKEC 405
            SLTQPRSLQQPSFLVPYMLCRNLPYGFIQELVRTTHQDEEVFKQIFIPILQGLALAAKEC
Sbjct: 475  SLTQPRSLQQPSFLVPYMLCRNLPYGFIQELVRTTHQDEEVFKQIFIPILQGLALAAKEC 534

Query: 406  SLDSDYFKYPLMALGELCETKFGKTHPVCNLVASLRLWLPKSLSPGCGRELQRLSYLGAF 465
            SLDSDYFKYPLMALGELCETKFGKTHPVCNLVASLRLWLPKSLSPGCGRELQRLSYLGAF
Sbjct: 535  SLDSDYFKYPLMALGELCETKFGKTHPVCNLVASLRLWLPKSLSPGCGRELQRLSYLGAF 594

Query: 466  FSFSVFAEDDVKVVEKYFSGPAITLENTRVVSQSLQHYLELGRQELFKILHSILLNGETR 525
            FSFSVFAEDDVKVVEKYFSGPAITLENTRVVSQSLQHYLELGRQELFKILHSILLNGETR
Sbjct: 595  FSFSVFAEDDVKVVEKYFSGPAITLENTRVVSQSLQHYLELGRQELFKILHSILLNGETR 654

Query: 526  EAALSYMAAVVNANMKKAQMQTDDRLVSTDGFMLNFLWVLQQLSTKIKLETVDPTYIFHP 585
            EAALSYMAAVVNANMKKAQMQTDDRLVSTDGFMLNFLWVLQQLSTKIKLETVDPTYIFHP
Sbjct: 655  EAALSYMAAVVNANMKKAQMQTDDRLVSTDGFMLNFLWVLQQLSTKIKLETVDPTYIFHP 714

Query: 586  RCRITLPNDETRVNATMEDVNDWLTELYGDQPPFSEPKFPTECFFLTLHAHHLSILPSCR 645
            RCRITLPNDETRVNATMEDVNDWLTELYGDQPPFSEPKFPTECFFLTLHAHHLSILPSCR
Sbjct: 715  RCRITLPNDETRVNATMEDVNDWLTELYGDQPPFSEPKFPTECFFLTLHAHHLSILPSCR 774

Query: 646  RYIRRLRAIRELNRTVEDLKNNESQWKDSPLATRHREMLKRCKTQLKKLVRCKACADAGL 705
            RYIRRLRAIRELNRTVEDLKNNESQWKDSPLATRHREMLKRCKTQLKKLVRCKACADAGL
Sbjct: 775  RYIRRLRAIRELNRTVEDLKNNESQWKDSPLATRHREMLKRCKTQLKKLVRCKACADAGL 834

Query: 706  LDESFLRRCLNFYGLLIQLLLRILDPAYPDITLPLNSDVPKVFAALPEFYVEDVAEFLFF 765
            LDESFLRRCLNFYGLLIQLLLRILDPAYPDITLPLNSDVPKVFAALPEFYVEDVAEFLFF
Sbjct: 835  LDESFLRRCLNFYGLLIQLLLRILDPAYPDITLPLNSDVPKVFAALPEFYVEDVAEFLFF 894

Query: 766  IVQYSPQALYEPCTQDIVMFLVVMLCNQNYIRNPYLVAKLVEVMFMTNPAVQPRTQKFFE 825
            IVQYSPQALYEPCTQDIVMFLVVMLCNQNYIRNPYLVAKLVEVMFMTNPAVQPRTQKFFE
Sbjct: 895  IVQYSPQALYEPCTQDIVMFLVVMLCNQNYIRNPYLVAKLVEVMFMTNPAVQPRTQKFFE 954

Query: 826  MIENHPLSTKLLVPSLMKFYTDVEHTGATSEFYDKFTIRYHISTIFKSLWQNIAHHGTFM 885
            MIENHPLSTKLLVPSLMKFYTDVEHTGATSEFYDKFTIRYHISTIFKSLWQNIAHHGTFM
Sbjct: 955  MIENHPLSTKLLVPSLMKFYTDVEHTGATSEFYDKFTIRYHISTIFKSLWQNIAHHGTFM 1014

Query: 886  EEFNSGKQFVRYINMLINDTTFLLDESLESLKRIHEVQEEMKNKEQWDQLPRDQQQARQS 945
            EEFNSGKQFVRYINMLINDTTFLLDESLESLKRIHEVQEEMKNKEQWDQLPRDQQQARQS
Sbjct: 1015 EEFNSGKQFVRYINMLINDTTFLLDESLESLKRIHEVQEEMKNKEQWDQLPRDQQQARQS 1074

Query: 946  QLAQDERVSRSYLALATETVDMFHILTKQVQKPFLRPELGPRLAAMLNFNLQQLCGPKCR 1005
            QLAQDERVSRSYLALATETVDMFHILTKQVQKPFLRPELGPRLAAMLNFNLQQLCGPKCR
Sbjct: 1075 QLAQDERVSRSYLALATETVDMFHILTKQVQKPFLRPELGPRLAAMLNFNLQQLCGPKCR 1134

Query: 1006 DLKVENPEKYGFEPKKLLDQLTDIYLQLDCARFAKAIADDQRSYSKELFEEVISKMRKAG 1065
            DLKVENPEKYGFEPKKLLDQLTDIYLQLDCARFAKAIADDQRSYSKELFEEVISKMRKAG
Sbjct: 1135 DLKVENPEKYGFEPKKLLDQLTDIYLQLDCARFAKAIADDQRSYSKELFEEVISKMRKAG 1194

Query: 1066 IKSTIAIEKFKLLAEKVEEIVAKNARAEIDYSDAPDEFRDPLMDTLMTDPVRLPSGTIMD 1125
            IKSTIAIEKFKLLAEKVEEIVAKNARAEIDYSDAPDEFRDPLMDTLMTDPVRLPSGTIMD
Sbjct: 1195 IKSTIAIEKFKLLAEKVEEIVAKNARAEIDYSDAPDEFRDPLMDTLMTDPVRLPSGTIMD 1254

Query: 1126 RSIILRHLLNSPTDPFNRQTLTESMLEPVPELKEQIQAWMREKQNSDH 1173
            RSIILRHLLNSPTDPFNRQTLTESMLEPVPELKEQIQAWMREKQNSDH
Sbjct: 1255 RSIILRHLLNSPTDPFNRQTLTESMLEPVPELKEQIQAWMREKQNSDH 1302



 Score =  527 bits (1357), Expect = e-149
 Identities = 276/285 (96%), Positives = 276/285 (96%), Gaps = 3/285 (1%)

Query: 1   MEELSADEIRRRRLARLAGGQTSQPTTPLTSPQRENPPGPPIAASAPGPSQSLGLNVHNM 60
           MEELSADEIRRRRLARLAGGQTSQPTTPLTSPQRENPPGPPIAASAPGPSQSLGLNVHNM
Sbjct: 1   MEELSADEIRRRRLARLAGGQTSQPTTPLTSPQRENPPGPPIAASAPGPSQSLGLNVHNM 60

Query: 61  TPATSPIGASGVAHRSQSSEGVSSLSSSPSNSLETQSQSLSRSQSMDIDGVSCEKSMSQV 120
           TPATSPIGASGVAHRSQSSEGVSSLSSSPSNSLETQSQSLSRSQSMDIDGVSCEKSMSQV
Sbjct: 61  TPATSPIGASGVAHRSQSSEGVSSLSSSPSNSLETQSQSLSRSQSMDIDGVSCEKSMSQV 120

Query: 121 DVDSGIENMEVDENDRREKRSLSDKEPSSGPEVSEEQALQLVCKIFRVSWKDRDRDVIFL 180
           DVDSGIENMEVDENDRREKRSLSDKEPSSGPEVSEEQALQLVCKIFRVSWKDRDRDVIFL
Sbjct: 121 DVDSGIENMEVDENDRREKRSLSDKEPSSGPEVSEEQALQLVCKIFRVSWKDRDRDVIFL 180

Query: 181 SSLSAQFKQNPKEVFSDFKDLIGQILMEVLMMSTQTRDENPFASLTATSQPIAAAARSPD 240
           SSLSAQFKQNPKEVFSDFKDLIGQILMEVLMMSTQTRDENPFASLTATSQPIAAAARSPD
Sbjct: 181 SSLSAQFKQNPKEVFSDFKDLIGQILMEVLMMSTQTRDENPFASLTATSQPIAAAARSPD 240

Query: 241 RNLLLNTGSNPGTSPMFCSVASFGASSLSSLGASGGA---SNWDS 282
           RNLLLNTGSNPGTSPMFCSVASFGASSLSSL  S  A   S W S
Sbjct: 241 RNLLLNTGSNPGTSPMFCSVASFGASSLSSLYESSPAPTPSFWSS 285


>gi|38327029 ubiquitination factor E4A [Homo sapiens]
          Length = 1073

 Score =  277 bits (708), Expect = 5e-74
 Identities = 246/931 (26%), Positives = 434/931 (46%), Gaps = 89/931 (9%)

Query: 294  ETDMLNYLIECFDRVGIEEKKAPKMCSQPAV---SQLLSNIRSQCISHTALVLQGSLTQP 350
            E  +  YL  CF R   E  K P+     AV   +  +SN R+  ++    V Q    Q 
Sbjct: 170  ERHIFCYLYSCFQRAKEEITKVPENLLPFAVQCRNLTVSNTRTVLLTPEIYVDQNIHEQL 229

Query: 351  RSLQQPSFLVPYMLCRNLPYG----FIQELVRTTHQDEEV--FKQIFIPILQGLALAAKE 404
              L   +          + +     F++E++     DEEV  F ++ IP+   L    K+
Sbjct: 230  VDLMLEAIQGAREYMNKIYFEDVTEFLEEVIEALILDEEVRTFPEVMIPVFDILLGRIKD 289

Query: 405  CSLDSDYFKYPLMALGELCETKFGKTHPVCNLVASLRLWLPKSLSPGCGRELQRLSYLGA 464
              L        L  L      K          +A + +   +   P  G+  Q+ + LG 
Sbjct: 290  LELCQILLYAYLDILLYFTRQKD---------MAKVFVEYIQPKDPTNGQMYQK-TLLGV 339

Query: 465  FFSFSVFAEDDVKVVEK--YFSGPAITL-ENTRVVSQSLQHYLELGRQELFKILHSIL-L 520
              S S   +    VVE   YF  P+ +  +  +V   ++  ++    ++++++L ++L L
Sbjct: 340  ILSISCLLKTP-GVVENHGYFLNPSRSSPQEIKVQEANIHQFMAQFHEKIYQMLKNLLQL 398

Query: 521  NGETREAALSYMAAVVNANMKKAQMQTDD------RLVSTDGFMLNFLWVLQQLSTKI-- 572
            + ET+   LS++   ++AN  + ++  +       ++ ++D F LN    L +L      
Sbjct: 399  SPETKHCILSWLGNCLHANAGRTKIWANQMPEIFFQMYASDAFFLNLGAALLKLCQPFCK 458

Query: 573  ----KLETVDPTYIFHPRCRITLPNDETRV--NATMEDVNDWLTELYGDQPPFSEPKFPT 626
                +L T +PTY     C +   NDE R   N  M  ++     +    P   EPKFP 
Sbjct: 459  PRSSRLLTFNPTY-----CALKELNDEERKIKNVHMRGLDKETCLI----PAVQEPKFPQ 509

Query: 627  ECFFLTLHAHHLSILPSCRRYIRRLRAIRELNRTVEDLKNNESQWKD-----SPLATRHR 681
                +T +      L     Y+   R   ++ +  ++L   +  W+D     SP A   R
Sbjct: 510  NYNLVTENL----ALTEYTLYLGFHRLHDQMVKINQNLHRLQVAWRDAQQSSSPAADNLR 565

Query: 682  EMLKRCKTQLKKLVRCKACADAGLLDESFLRRCLNFYGLLIQLLLRIL---DPAYP-DIT 737
            E       Q ++L+         + +   L+ CLN    +  LL+++    + + P ++T
Sbjct: 566  E-------QFERLMTIYLSTKTAMTEPQMLQNCLNLQVSMAVLLVQLAIGNEGSQPIELT 618

Query: 738  LPLNSDVPKVFAALPEFYVEDVAEFLFFIVQYSPQALYEPCT--QDIVMFLVVMLCNQNY 795
             PL  D     A +PEF+ +++ +FL F+ +++   L       + ++ F+ +   +   
Sbjct: 619  FPL-PDGYSSLAYVPEFFADNLGDFLIFLRRFADDILETSADSLEHVLHFITIFTGSIER 677

Query: 796  IRNPYLVAKLVEVMFMTNPAVQPRTQKFFEMIENHPLS------TKLLVPSLMKFYTDVE 849
            ++NP+L AKL EV+    P +          + +             L  +L+K + D+E
Sbjct: 678  MKNPHLRAKLAEVLEAVMPHLDQTPNPLVSSVFHRKRVFCNFQYAPQLAEALIKVFVDIE 737

Query: 850  HTGATSEFYDKFTIRYHISTIFKSLW---------QNIAHHGTFMEEFNSGKQFVRYINM 900
             TG   +F  KF  R  +  I + +W         +++A + +   E  +   F+R++N+
Sbjct: 738  FTGDPHQFEQKFNYRRPMYPILRYMWGTDTYRESIKDLADYASKNLEAMNPPLFLRFLNL 797

Query: 901  LINDTTFLLDESLESLKRIHEVQEEMKNKEQWDQLPRDQQQARQSQLAQDERVSRSYLAL 960
            L+ND  FLLDE+++ L +I ++Q+  K++ +WD L  + ++ +++ L    +++R +  +
Sbjct: 798  LMNDAIFLLDEAIQYLSKI-KIQQIEKDRGEWDSLTPEARREKEAGLQMFGQLARFHNIM 856

Query: 961  ATETVDMFHILTKQVQKPFLRPELGPRLAAMLNFNLQQLCGPKCRDLKVENPEKYGFEPK 1020
            + ET+     LT +++  F+ P L  R+ +MLN+ LQ L GPK   LKV++  ++ F+P+
Sbjct: 857  SNETIGTLAFLTSEIKSLFVHPFLAERIISMLNYFLQHLVGPKMGALKVKDFSEFDFKPQ 916

Query: 1021 KLLDQLTDIYLQL-DCARFAKAIADDQRSYSKELFEEVISKMRKAGIKSTIAIEKFKLLA 1079
            +L+  +  IYL L D   F   +  D RSYS  LF + +  ++K   K    I  F  LA
Sbjct: 917  QLVSDICTIYLNLGDEENFCATVPKDGRSYSPTLFAQTVRVLKKIN-KPGNMIMAFSNLA 975

Query: 1080 EKVEEIVAKNARAEIDYSDAPDEFRDPLMDTLMTDPVRLPSGTI-MDRSIILRHLLNSPT 1138
            E+++ +     + E  Y+DA DEF DP+M TLM DPV LPS  + +DRS I RHLL+  T
Sbjct: 976  ERIKSLADLQQQEEETYADACDEFLDPIMSTLMCDPVVLPSSRVTVDRSTIARHLLSDQT 1035

Query: 1139 DPFNRQTLTESMLEPVPELKEQIQAWMREKQ 1169
            DPFNR  LT   + P  ELKE+IQ W+ E++
Sbjct: 1036 DPFNRSPLTMDQIRPNTELKEKIQRWLAERK 1066


>gi|119943102 CREB binding protein isoform b [Homo sapiens]
          Length = 2404

 Score = 43.1 bits (100), Expect = 0.002
 Identities = 47/188 (25%), Positives = 73/188 (38%), Gaps = 20/188 (10%)

Query: 22   TSQPTTPL-----TSPQRENPPGPPIAASAPG-PSQSLGLNVHNMTPATSPIGASGVAHR 75
            T QP TP+      +PQ       P+ A  PG P      ++ N  P  S + AS   + 
Sbjct: 889  TPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRVPTPSSV-ASAETNS 947

Query: 76   SQSSEGVSSLSSSPSNSLET------QSQSLSRSQSMDIDGVSCEKSMSQVDV-DSGIEN 128
             Q    V  L        E       +S+   RS+ M+ D     +   + D+ +   E 
Sbjct: 948  QQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSEMMEEDLQGASQVKEETDIAEQKSEP 1007

Query: 129  MEVDENDRREKRSLSDKEPSS--GPEVSEEQALQLVCKIFRVSWKDRDRDVIFLSSLSAQ 186
            MEVDE     K  + ++E SS  G         Q   KIF    K  +     + +L A 
Sbjct: 1008 MEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQPRKKIF----KPEELRQALMPTLEAL 1063

Query: 187  FKQNPKEV 194
            ++Q+P+ +
Sbjct: 1064 YRQDPESL 1071


>gi|119943104 CREB binding protein isoform a [Homo sapiens]
          Length = 2442

 Score = 43.1 bits (100), Expect = 0.002
 Identities = 47/188 (25%), Positives = 73/188 (38%), Gaps = 20/188 (10%)

Query: 22   TSQPTTPL-----TSPQRENPPGPPIAASAPG-PSQSLGLNVHNMTPATSPIGASGVAHR 75
            T QP TP+      +PQ       P+ A  PG P      ++ N  P  S + AS   + 
Sbjct: 927  TPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRVPTPSSV-ASAETNS 985

Query: 76   SQSSEGVSSLSSSPSNSLET------QSQSLSRSQSMDIDGVSCEKSMSQVDV-DSGIEN 128
             Q    V  L        E       +S+   RS+ M+ D     +   + D+ +   E 
Sbjct: 986  QQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSEMMEEDLQGASQVKEETDIAEQKSEP 1045

Query: 129  MEVDENDRREKRSLSDKEPSS--GPEVSEEQALQLVCKIFRVSWKDRDRDVIFLSSLSAQ 186
            MEVDE     K  + ++E SS  G         Q   KIF    K  +     + +L A 
Sbjct: 1046 MEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQPRKKIF----KPEELRQALMPTLEAL 1101

Query: 187  FKQNPKEV 194
            ++Q+P+ +
Sbjct: 1102 YRQDPESL 1109


>gi|7662344 U-box domain containing 5 isoform a [Homo sapiens]
          Length = 541

 Score = 40.0 bits (92), Expect = 0.013
 Identities = 25/75 (33%), Positives = 39/75 (52%), Gaps = 7/75 (9%)

Query: 1098 DAPDEFRDPLMDTLMTDPVRLPSGTIMDRSIILRHLLNS------PTDPFNRQTLT-ESM 1150
            D P+EF DP+   +M  P+ LPSG ++D+S + +   +       P+DPF     T  S 
Sbjct: 258  DVPEEFLDPITLEIMPCPMLLPSGKVIDQSTLEKCNRSEATWGRVPSDPFTGVAFTPHSQ 317

Query: 1151 LEPVPELKEQIQAWM 1165
              P P LK +I  ++
Sbjct: 318  PLPHPSLKARIDHFL 332


>gi|40806196 U-box domain containing 5 isoform b [Homo sapiens]
          Length = 487

 Score = 40.0 bits (92), Expect = 0.013
 Identities = 25/75 (33%), Positives = 39/75 (52%), Gaps = 7/75 (9%)

Query: 1098 DAPDEFRDPLMDTLMTDPVRLPSGTIMDRSIILRHLLNS------PTDPFNRQTLT-ESM 1150
            D P+EF DP+   +M  P+ LPSG ++D+S + +   +       P+DPF     T  S 
Sbjct: 258  DVPEEFLDPITLEIMPCPMLLPSGKVIDQSTLEKCNRSEATWGRVPSDPFTGVAFTPHSQ 317

Query: 1151 LEPVPELKEQIQAWM 1165
              P P LK +I  ++
Sbjct: 318  PLPHPSLKARIDHFL 332


>gi|4503257 death-domain associated protein isoform a [Homo sapiens]
          Length = 740

 Score = 39.3 bits (90), Expect = 0.022
 Identities = 40/205 (19%), Positives = 83/205 (40%), Gaps = 19/205 (9%)

Query: 70  SGVAHRSQSSEGVSSLSSSPSNSLETQSQSLSRSQSMDIDGVSCEKSMSQVDVDSGIENM 129
           SG      +S+G  S S + ++  + +       +  + +      S  + D++   E  
Sbjct: 415 SGEGPSGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQ 474

Query: 130 EVDENDRREKRSLS----DKEPSSGPEVSEEQALQLVCKIFRVSWKDRDRDVIFLSSLSA 185
           E DE +  E+ + +    DK P S  ++S E+ L+   +I R S + +++  I   SL +
Sbjct: 475 EDDEEEDEEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLS 534

Query: 186 QFK------------QNPKEVFSDFKDLIGQIL---MEVLMMSTQTRDENPFASLTATSQ 230
           +              + P+E+  + +  + Q+    +E L + T +  E   +S    S+
Sbjct: 535 EEPLAPSSIDAESNGEQPEELTLEEESPVSQLFELEIEALPLDTPSSVETDISSSRKQSE 594

Query: 231 PIAAAARSPDRNLLLNTGSNPGTSP 255
                       ++ +T  N G SP
Sbjct: 595 EPFTTVLENGAGMVSSTSFNGGVSP 619


>gi|215422388 death-domain associated protein isoform a [Homo
           sapiens]
          Length = 740

 Score = 39.3 bits (90), Expect = 0.022
 Identities = 40/205 (19%), Positives = 83/205 (40%), Gaps = 19/205 (9%)

Query: 70  SGVAHRSQSSEGVSSLSSSPSNSLETQSQSLSRSQSMDIDGVSCEKSMSQVDVDSGIENM 129
           SG      +S+G  S S + ++  + +       +  + +      S  + D++   E  
Sbjct: 415 SGEGPSGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQ 474

Query: 130 EVDENDRREKRSLS----DKEPSSGPEVSEEQALQLVCKIFRVSWKDRDRDVIFLSSLSA 185
           E DE +  E+ + +    DK P S  ++S E+ L+   +I R S + +++  I   SL +
Sbjct: 475 EDDEEEDEEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLS 534

Query: 186 QFK------------QNPKEVFSDFKDLIGQIL---MEVLMMSTQTRDENPFASLTATSQ 230
           +              + P+E+  + +  + Q+    +E L + T +  E   +S    S+
Sbjct: 535 EEPLAPSSIDAESNGEQPEELTLEEESPVSQLFELEIEALPLDTPSSVETDISSSRKQSE 594

Query: 231 PIAAAARSPDRNLLLNTGSNPGTSP 255
                       ++ +T  N G SP
Sbjct: 595 EPFTTVLENGAGMVSSTSFNGGVSP 619


>gi|215422366 death-domain associated protein isoform b [Homo
           sapiens]
          Length = 752

 Score = 39.3 bits (90), Expect = 0.022
 Identities = 40/205 (19%), Positives = 83/205 (40%), Gaps = 19/205 (9%)

Query: 70  SGVAHRSQSSEGVSSLSSSPSNSLETQSQSLSRSQSMDIDGVSCEKSMSQVDVDSGIENM 129
           SG      +S+G  S S + ++  + +       +  + +      S  + D++   E  
Sbjct: 427 SGEGPSGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQ 486

Query: 130 EVDENDRREKRSLS----DKEPSSGPEVSEEQALQLVCKIFRVSWKDRDRDVIFLSSLSA 185
           E DE +  E+ + +    DK P S  ++S E+ L+   +I R S + +++  I   SL +
Sbjct: 487 EDDEEEDEEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLS 546

Query: 186 QFK------------QNPKEVFSDFKDLIGQIL---MEVLMMSTQTRDENPFASLTATSQ 230
           +              + P+E+  + +  + Q+    +E L + T +  E   +S    S+
Sbjct: 547 EEPLAPSSIDAESNGEQPEELTLEEESPVSQLFELEIEALPLDTPSSVETDISSSRKQSE 606

Query: 231 PIAAAARSPDRNLLLNTGSNPGTSP 255
                       ++ +T  N G SP
Sbjct: 607 EPFTTVLENGAGMVSSTSFNGGVSP 631


>gi|56181387 STIP1 homology and U-box containing protein 1 [Homo
            sapiens]
          Length = 303

 Score = 38.9 bits (89), Expect = 0.029
 Identities = 26/71 (36%), Positives = 32/71 (45%), Gaps = 1/71 (1%)

Query: 1098 DAPDEFRDPLMDTLMTDPVRLPSGTIMDRSIILRHLLN-SPTDPFNRQTLTESMLEPVPE 1156
            D PD     +   LM +P   PSG   DR  I  HL      DP  R  LT+  L P   
Sbjct: 226  DIPDYLCGKISFELMREPCITPSGITYDRKDIEEHLQRVGHFDPVTRSPLTQEQLIPNLA 285

Query: 1157 LKEQIQAWMRE 1167
            +KE I A++ E
Sbjct: 286  MKEVIDAFISE 296


>gi|40068059 CBF1 interacting corepressor [Homo sapiens]
          Length = 450

 Score = 38.1 bits (87), Expect = 0.050
 Identities = 25/76 (32%), Positives = 40/76 (52%), Gaps = 5/76 (6%)

Query: 74  HRSQSSEGVSSLSSSPSNSLETQSQSLSRSQSMDIDGVSCEKSMSQVDVDSGIENMEVDE 133
           H+S SS   SS SSS + + E+ S+S S ++   I     +K+       SG  N + +E
Sbjct: 255 HKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKC-----SGHNNSDSEE 309

Query: 134 NDRREKRSLSDKEPSS 149
            D+ +KR L ++  SS
Sbjct: 310 KDKSKKRKLHEELSSS 325


>gi|50345997 E1A binding protein p300 [Homo sapiens]
          Length = 2414

 Score = 38.1 bits (87), Expect = 0.050
 Identities = 42/188 (22%), Positives = 79/188 (42%), Gaps = 18/188 (9%)

Query: 25   PTTPLTSPQRENPPGPPIAASA------PGPSQSLGLNVHNMT-PATSPIGASGVAHRSQ 77
            PT P T   ++  P  P A SA      P   QS   +V   T P   P  A+ ++  + 
Sbjct: 886  PTPPTTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVPTPTAPLLPPQPATPLSQPAV 945

Query: 78   SSEG-VSSLSSSPSNSLETQ-------SQSLSRSQSMDIDGVSCEKSMSQVDVDSGIENM 129
            S EG VS+  S+ S  + +Q       SQ +     M++D      +  +   +S +E+ 
Sbjct: 946  SIEGQVSNPPSTSSTEVNSQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVEDC 1005

Query: 130  EVDENDRREKRS---LSDKEPSSGPEVSEEQALQLVCKIFRVSWKDRDRDVIFLSSLSAQ 186
            +++  +  E+ +      KE    P  S  Q+     +  +  +K  +     + +L A 
Sbjct: 1006 KMESTETEERSTELKTEIKEEEDQPSTSATQSSPAPGQSKKKIFKPEELRQALMPTLEAL 1065

Query: 187  FKQNPKEV 194
            ++Q+P+ +
Sbjct: 1066 YRQDPESL 1073


>gi|189571685 WD repeat, sterile alpha motif and U-box domain
            containing 1 [Homo sapiens]
          Length = 476

 Score = 38.1 bits (87), Expect = 0.050
 Identities = 27/110 (24%), Positives = 44/110 (40%), Gaps = 1/110 (0%)

Query: 1061 MRKAGIKSTIAIEKFKLLAEKVEEIVAKNARAEIDYSDAPDEFRDPLMDTLMTDPVRLPS 1120
            + K  +   + IE   L ++ + +I     + +   S  PDEF  P+   LM DPV    
Sbjct: 366  LTKESLADDLKIESLGLRSKVLRKIEELRTKVKSLSSGIPDEFICPITRELMKDPVIASD 425

Query: 1121 GTIMDRSIILRHLLNSP-TDPFNRQTLTESMLEPVPELKEQIQAWMREKQ 1169
            G   ++  +   +     T P     L  ++L P   LK  I  W+   Q
Sbjct: 426  GYSYEKEAMENWISKKKRTSPMTNLVLPSAVLTPNRTLKMAINRWLETHQ 475


>gi|189571683 WD repeat, sterile alpha motif and U-box domain
            containing 1 [Homo sapiens]
          Length = 476

 Score = 38.1 bits (87), Expect = 0.050
 Identities = 27/110 (24%), Positives = 44/110 (40%), Gaps = 1/110 (0%)

Query: 1061 MRKAGIKSTIAIEKFKLLAEKVEEIVAKNARAEIDYSDAPDEFRDPLMDTLMTDPVRLPS 1120
            + K  +   + IE   L ++ + +I     + +   S  PDEF  P+   LM DPV    
Sbjct: 366  LTKESLADDLKIESLGLRSKVLRKIEELRTKVKSLSSGIPDEFICPITRELMKDPVIASD 425

Query: 1121 GTIMDRSIILRHLLNSP-TDPFNRQTLTESMLEPVPELKEQIQAWMREKQ 1169
            G   ++  +   +     T P     L  ++L P   LK  I  W+   Q
Sbjct: 426  GYSYEKEAMENWISKKKRTSPMTNLVLPSAVLTPNRTLKMAINRWLETHQ 475


>gi|189571681 WD repeat, sterile alpha motif and U-box domain
            containing 1 [Homo sapiens]
          Length = 476

 Score = 38.1 bits (87), Expect = 0.050
 Identities = 27/110 (24%), Positives = 44/110 (40%), Gaps = 1/110 (0%)

Query: 1061 MRKAGIKSTIAIEKFKLLAEKVEEIVAKNARAEIDYSDAPDEFRDPLMDTLMTDPVRLPS 1120
            + K  +   + IE   L ++ + +I     + +   S  PDEF  P+   LM DPV    
Sbjct: 366  LTKESLADDLKIESLGLRSKVLRKIEELRTKVKSLSSGIPDEFICPITRELMKDPVIASD 425

Query: 1121 GTIMDRSIILRHLLNSP-TDPFNRQTLTESMLEPVPELKEQIQAWMREKQ 1169
            G   ++  +   +     T P     L  ++L P   LK  I  W+   Q
Sbjct: 426  GYSYEKEAMENWISKKKRTSPMTNLVLPSAVLTPNRTLKMAINRWLETHQ 475


>gi|126090892 aggrecan isoform 2 precursor [Homo sapiens]
          Length = 2416

 Score = 37.7 bits (86), Expect = 0.065
 Identities = 35/142 (24%), Positives = 55/142 (38%), Gaps = 15/142 (10%)

Query: 14   LARLAGGQTSQPTTPLTSPQRENPPGPPIAASAPGPSQSLGLNVHNMTPATSPIGASGVA 73
            ++ L  G+  + T P        P G  +  +APG  +  GL    +   T+P       
Sbjct: 1277 ISGLPSGEVLETTAPGVEEISGLPSGEVLETTAPGVDEISGLPSGEVLETTAP------- 1329

Query: 74   HRSQSSEGVSSLSSSPSNS-LETQSQSLSRSQSMDIDGVSCEKSMSQVDVDSGIENMEVD 132
                   GV  +S  PS   LET + ++     +   G   E S+S V+  SG+ + EV 
Sbjct: 1330 -------GVEEISGLPSGEVLETSTSAVGDLSGLPSGGEVLEISVSGVEDISGLPSGEVV 1382

Query: 133  ENDRREKRSLSDKEPSSGPEVS 154
            E        +S+     G E S
Sbjct: 1383 ETSASGIEDVSELPSGEGLETS 1404


>gi|126090883 aggrecan isoform 1 precursor [Homo sapiens]
          Length = 2317

 Score = 37.7 bits (86), Expect = 0.065
 Identities = 35/142 (24%), Positives = 55/142 (38%), Gaps = 15/142 (10%)

Query: 14   LARLAGGQTSQPTTPLTSPQRENPPGPPIAASAPGPSQSLGLNVHNMTPATSPIGASGVA 73
            ++ L  G+  + T P        P G  +  +APG  +  GL    +   T+P       
Sbjct: 1277 ISGLPSGEVLETTAPGVEEISGLPSGEVLETTAPGVDEISGLPSGEVLETTAP------- 1329

Query: 74   HRSQSSEGVSSLSSSPSNS-LETQSQSLSRSQSMDIDGVSCEKSMSQVDVDSGIENMEVD 132
                   GV  +S  PS   LET + ++     +   G   E S+S V+  SG+ + EV 
Sbjct: 1330 -------GVEEISGLPSGEVLETSTSAVGDLSGLPSGGEVLEISVSGVEDISGLPSGEVV 1382

Query: 133  ENDRREKRSLSDKEPSSGPEVS 154
            E        +S+     G E S
Sbjct: 1383 ETSASGIEDVSELPSGEGLETS 1404


>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
          Length = 2968

 Score = 37.7 bits (86), Expect = 0.065
 Identities = 28/98 (28%), Positives = 39/98 (39%)

Query: 54   GLNVHNMTPATSPIGASGVAHRSQSSEGVSSLSSSPSNSLETQSQSLSRSQSMDIDGVSC 113
            G    N + A+S   +   +  S SS   SS SSS S+S  + S S S S S      S 
Sbjct: 2596 GTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2655

Query: 114  EKSMSQVDVDSGIENMEVDENDRREKRSLSDKEPSSGP 151
              S S     S   +   DE+        +   P++GP
Sbjct: 2656 SSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGP 2693



 Score = 33.5 bits (75), Expect = 1.2
 Identities = 24/71 (33%), Positives = 34/71 (47%)

Query: 43   AASAPGPSQSLGLNVHNMTPATSPIGASGVAHRSQSSEGVSSLSSSPSNSLETQSQSLSR 102
            AAS    S S   +  + + ++S   +S  +  S SS   SS SSS S+S  + S S S 
Sbjct: 2609 AASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2668

Query: 103  SQSMDIDGVSC 113
            S S   +  SC
Sbjct: 2669 SSSTTDEDSSC 2679


>gi|150010577 tyrosine kinase, non-receptor, 1 [Homo sapiens]
          Length = 661

 Score = 37.7 bits (86), Expect = 0.065
 Identities = 36/141 (25%), Positives = 58/141 (41%), Gaps = 21/141 (14%)

Query: 16  RLAGGQTSQPTTPLTSPQRENPPG----PPIAASAPGPSQSLGLNV---HNMTPATSPIG 68
           R  GG +S P         + PPG    PP+++S+P PSQ     +       P   P+G
Sbjct: 507 RPTGGGSSPPEIRQARAVPQGPPGLPPRPPLSSSSPQPSQPSRERLPWPKRKPPHNHPMG 566

Query: 69  ASGVAHRSQSSEGVSSLSSSPSNSLETQSQSLSRSQSMDIDGVS---CEKSMSQV--DVD 123
             G    +  S G+ S         + + Q       + + GV+   C+ ++     DV 
Sbjct: 567 MPGARKAAALSGGLLS---------DPELQRKIMEVELSVHGVTHQECQTALGATGGDVV 617

Query: 124 SGIENMEVDENDRREKRSLSD 144
           S I N++VD+      RS +D
Sbjct: 618 SAIRNLKVDQLFHLSSRSRAD 638


>gi|19924099 synapsin I isoform Ia [Homo sapiens]
          Length = 705

 Score = 37.4 bits (85), Expect = 0.085
 Identities = 29/102 (28%), Positives = 46/102 (45%), Gaps = 3/102 (2%)

Query: 11  RRRLARLAGGQTSQPTTPLTSPQRENPPGPPIAASAPGPSQSLGLNVHNMTPATSPIGAS 70
           RRRL+  +    + P   +T  QR  PP PP  A +PG +   G      +   +P  A+
Sbjct: 5   RRRLSD-SNFMANLPNGYMTDLQRPQPPPPPPGAHSPGATPGPGTATAERSSGVAP--AA 61

Query: 71  GVAHRSQSSEGVSSLSSSPSNSLETQSQSLSRSQSMDIDGVS 112
             A  S  S G     SS SN+++  + + + + S  + G S
Sbjct: 62  SPAAPSPGSSGGGGFFSSLSNAVKQTTAAAAATFSEQVGGGS 103


>gi|19924097 synapsin I isoform Ib [Homo sapiens]
          Length = 669

 Score = 37.4 bits (85), Expect = 0.085
 Identities = 29/102 (28%), Positives = 46/102 (45%), Gaps = 3/102 (2%)

Query: 11  RRRLARLAGGQTSQPTTPLTSPQRENPPGPPIAASAPGPSQSLGLNVHNMTPATSPIGAS 70
           RRRL+  +    + P   +T  QR  PP PP  A +PG +   G      +   +P  A+
Sbjct: 5   RRRLSD-SNFMANLPNGYMTDLQRPQPPPPPPGAHSPGATPGPGTATAERSSGVAP--AA 61

Query: 71  GVAHRSQSSEGVSSLSSSPSNSLETQSQSLSRSQSMDIDGVS 112
             A  S  S G     SS SN+++  + + + + S  + G S
Sbjct: 62  SPAAPSPGSSGGGGFFSSLSNAVKQTTAAAAATFSEQVGGGS 103


>gi|13994287 BTE-binding protein 4 [Homo sapiens]
          Length = 252

 Score = 36.6 bits (83), Expect = 0.14
 Identities = 22/61 (36%), Positives = 28/61 (45%)

Query: 31  SPQRENPPGPPIAASAPGPSQSLGLNVHNMTPATSPIGASGVAHRSQSSEGVSSLSSSPS 90
           SP    PP PP AAS PGP  +   ++   +      G  G A    S    SS +SSPS
Sbjct: 52  SPGTPGPPPPPPAASGPGPGAAAAPHLLAASILADLRGGPGAAPGGASPASSSSAASSPS 111

Query: 91  N 91
           +
Sbjct: 112 S 112


>gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [Homo
            sapiens]
          Length = 3969

 Score = 36.6 bits (83), Expect = 0.14
 Identities = 58/266 (21%), Positives = 98/266 (36%), Gaps = 6/266 (2%)

Query: 2    EELSADEIRRRRLARLAGGQTSQPTTPLTSPQRENPPGPPIAASAPGPSQSLGLNVHNMT 61
            E  S     R R  RL+  + S  T P +     +    P+A SA  P+ +   +    +
Sbjct: 747  EPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQS 806

Query: 62   PATSPIGASGVAHRSQSSEGVSSLSSSPSNSLETQSQSLSRSQSMDIDGVSCEKSMSQVD 121
              ++          S  +E  SS S +P     T      R ++ D    + E+     D
Sbjct: 807  GESAEKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKD---KAPEELSKDRD 863

Query: 122  VDSGIENMEVDENDR-REKRSLSDKEPSSGPEVSEEQALQLVCKIFRVS-WKDRDRDVIF 179
             D  +E  +  E DR REK +  +       + SE Q+   +  + RVS  K    DV  
Sbjct: 864  ADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQSSSALYPVGRVSKEKVVGEDVAT 923

Query: 180  LSSLSAQFKQNPKEVFSDFKDLIGQILMEVLMMSTQTRDENPFASLTATSQPIAAAARSP 239
             SS      +          D+    L +   + T+   +    +L  T+  +   A S 
Sbjct: 924  SSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEKTNLDLGPTAPSL 983

Query: 240  DRNLLLNTGSNPGTSPMFCSVASFGA 265
            ++   L   S P +S +  S +S G+
Sbjct: 984  EKEKTLCL-STPSSSTVKHSTSSIGS 1008



 Score = 34.3 bits (77), Expect = 0.72
 Identities = 21/61 (34%), Positives = 29/61 (47%), Gaps = 5/61 (8%)

Query: 37  PPGPPIAASAPG-----PSQSLGLNVHNMTPATSPIGASGVAHRSQSSEGVSSLSSSPSN 91
           PPGPP+    PG     P+ +        + A  P GA+  +  S SS   SS SSS ++
Sbjct: 41  PPGPPVGGGGPGAPPSPPAVAAAAAAAGSSGAGVPGGAAAASAASSSSASSSSSSSSSAS 100

Query: 92  S 92
           S
Sbjct: 101 S 101



 Score = 31.2 bits (69), Expect = 6.1
 Identities = 20/54 (37%), Positives = 25/54 (46%), Gaps = 3/54 (5%)

Query: 37  PPGPPIAASAPGPSQSLGLNVHNMTPATSPIGASGVAHRSQSSEGVSSLSSSPS 90
           PP PP  A+A   + S G  V     A S   +S  +  S SS   SS SS P+
Sbjct: 54  PPSPPAVAAAAAAAGSSGAGVPGGAAAASAASSSSASSSSSSS---SSASSGPA 104


>gi|51093836 hypothetical protein LOC126859 isoform 1 [Homo sapiens]
          Length = 1012

 Score = 36.6 bits (83), Expect = 0.14
 Identities = 33/146 (22%), Positives = 68/146 (46%), Gaps = 23/146 (15%)

Query: 970  ILTKQVQKPFLRPELGPRLAAMLNFNLQQLCGPKCRDLKVENPEKYGFEPKKLLDQLTDI 1029
            +L ++  K F+ PE+        +F   +    + R L+ EN E+   +P    ++    
Sbjct: 829  LLEEEAVKEFIEPEIDE------SFKEDEEESKEDRKLQEENKERAEEQPSTSTEK---- 878

Query: 1030 YLQLDCARFAKAIADDQRSYSKELFE-EVISKMRKAGIKSTIAIEKFKLLA------EKV 1082
                   +  + I +D+  +SK LFE +V+S  R++  + T+A +  + +A      EK+
Sbjct: 879  ------EKLIRFIGEDENVHSKPLFETDVLSSWRESAKQGTLAQKYLEAMAVIEHMQEKL 932

Query: 1083 EEIVAKNARAEIDYSDAPDEFRDPLM 1108
             E+  +  +AE  + DA ++    L+
Sbjct: 933  LEVENRARQAEEKFEDAYEKLHHTLI 958


>gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithorax
           homolog, Drosophila); translocated to, 3 [Homo sapiens]
          Length = 568

 Score = 36.2 bits (82), Expect = 0.19
 Identities = 34/139 (24%), Positives = 57/139 (41%), Gaps = 1/139 (0%)

Query: 56  NVHNMTPATSPIGASGVAHRSQSSEGVSSLSSSPSNSLETQSQSLSRSQSMDIDGVSCEK 115
           ++H  + ++S   +S  +  S SS   SS SSS S+S  + S S S S S     +   K
Sbjct: 145 SIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHK 204

Query: 116 SMSQVDVDSGIENMEVDENDRREKRSLSDKEPSSGPEVSEEQAL-QLVCKIFRVSWKDRD 174
                D        +    D  +    S K+P     + EE+ + ++  K  +   K+  
Sbjct: 205 EKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPKPMSKEPK 264

Query: 175 RDVIFLSSLSAQFKQNPKE 193
            D   L+  S Q K+ P +
Sbjct: 265 PDSNLLTITSGQDKKAPSK 283


>gi|38176300 nestin [Homo sapiens]
          Length = 1621

 Score = 35.8 bits (81), Expect = 0.25
 Identities = 37/160 (23%), Positives = 68/160 (42%), Gaps = 20/160 (12%)

Query: 908  LLDESLESLKRIHEVQEEMKNKEQWDQLPRDQQQARQSQLAQDERVSRSYLALATETVDM 967
            L  E+ E L+ + +     +NKE +  L ++ Q+  ++   +D+ + R    L TE    
Sbjct: 692  LTKENQEPLRSLED-----ENKEAFRSLEKENQEPLKTLEEEDQSIVRP---LETENHKS 743

Query: 968  FHILTKQVQKPF--LRPELGPRLAAMLNFNLQQLCGPKCRDLKVENPEKYGFEPKKLLDQ 1025
               L +Q Q+    L  E   R  ++   +           + +  PEK   EP K LDQ
Sbjct: 744  LRSLEEQDQETLRTLEKETQQRRRSLGEQD----------QMTLRPPEKVDLEPLKSLDQ 793

Query: 1026 LTDIYLQLDCARFAKAIADDQRSYSKELFEEVISKMRKAG 1065
                 L+ +   F K++ ++     K L  E++  ++ AG
Sbjct: 794  EIARPLENENQEFLKSLKEESVEAVKSLETEILESLKSAG 833


>gi|138175817 zinc finger protein 236 [Homo sapiens]
          Length = 1845

 Score = 35.8 bits (81), Expect = 0.25
 Identities = 32/150 (21%), Positives = 67/150 (44%), Gaps = 18/150 (12%)

Query: 18  AGGQTSQPTTPLTSPQRE-----NPPGPPIAASAPGPSQSLGLNVHNMTPATSPIGASGV 72
           A   +SQP++   S   +     + P P  +  +P P Q L + V              +
Sbjct: 342 ATSASSQPSSQAVSDVIQQLLELSEPAPVESGQSPQPGQQLSITVGIN---------QDI 392

Query: 73  AHRSQSSEGVSSLSSS--PSNSLETQSQSLSRSQSMDIDGVSCEKSMSQVDVDSGIENME 130
             ++  + G+SS+ ++  P++S   ++ S   +Q+ D+  VS E++    D +   E   
Sbjct: 393 LQQALENSGLSSIPAAAHPNDSCHAKT-SAPHAQNPDVSSVSNEQT-DPTDAEQEKEQES 450

Query: 131 VDENDRREKRSLSDKEPSSGPEVSEEQALQ 160
            ++ D++EK+ +  K P     + EE  ++
Sbjct: 451 PEKLDKKEKKMIKKKSPFLPGSIREENGVR 480


>gi|40538736 RAN binding protein 10 [Homo sapiens]
          Length = 620

 Score = 35.4 bits (80), Expect = 0.32
 Identities = 36/131 (27%), Positives = 64/131 (48%), Gaps = 11/131 (8%)

Query: 9   IRRRRLARLAGGQTSQPTTPLT-SPQRENP-PGPPIAASAPGPSQSLGLNVHNMTPATSP 66
           ++ R+   +  G  S+  +  + SP+ ++  PG P  +   GPS S   ++HN T A SP
Sbjct: 332 LKCRQFVEMVNGTDSEVRSLSSRSPKSQDSYPGSPSLSPRHGPSSS---HMHN-TGADSP 387

Query: 67  IGASGVAH----RSQSSEGVSSLSSSPSNSLETQS-QSLSRSQSMDIDGVSCEKSMSQVD 121
             ++GVA     ++ S     S SSS S+S  + S  S++ S+S   D    +   S  +
Sbjct: 388 SCSNGVASTKSKQNHSKYPAPSSSSSSSSSSSSSSPSSVNYSESNSTDSTKSQHHSSTSN 447

Query: 122 VDSGIENMEVD 132
            ++    ME++
Sbjct: 448 QETSDSEMEME 458


>gi|239742580 PREDICTED: similar to Putative POM121-like protein
           1-like [Homo sapiens]
          Length = 897

 Score = 35.0 bits (79), Expect = 0.42
 Identities = 35/144 (24%), Positives = 58/144 (40%), Gaps = 13/144 (9%)

Query: 25  PTTPLTSPQRENPPGPPIAASAPGPSQSL----GLNVHNMTPATSPIGASGVAHRSQSSE 80
           P+T   S ++  PPGP  ++S P P+ S        V ++ PAT    +     R   S 
Sbjct: 268 PSTAPVSGKKHRPPGPLFSSSDPLPATSYHSRDTAQVTSLIPATFTAASRDAGMRRTRSA 327

Query: 81  GVSSLSSSPSNSLETQSQSLSRSQSMDIDGVSCEKSMSQVDVDSGIENMEVDENDR---- 136
             ++ ++ P ++L   S SL  +    +DG      ++     +  +  EV  N R    
Sbjct: 328 PAAATAAPPPSTLNNTSGSLLNA----VDG-GPSHFLASATAAARAQRSEVRYNQRSQTS 382

Query: 137 REKRSLSDKEPSSGPEVSEEQALQ 160
           R +  L     SS    S  + LQ
Sbjct: 383 RTRSCLKRNASSSSSSHSSTEGLQ 406


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.133    0.387 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 44,367,353
Number of Sequences: 37866
Number of extensions: 2032627
Number of successful extensions: 11400
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 131
Number of HSP's that attempted gapping in prelim test: 11065
Number of HSP's gapped (non-prelim): 442
length of query: 1173
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1060
effective length of database: 13,968,660
effective search space: 14806779600
effective search space used: 14806779600
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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